LOCUS       DARYXW010000001        64995 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.001, whole genome shotgun sequence.
ACCESSION   DARYXW010000001 DARYXW010000000
VERSION     DARYXW010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 64995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64995
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.001"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            194..1429
                     /gene="arcA"
                     /locus_tag="TV191_000001"
     CDS             194..1429
                     /gene="arcA"
                     /locus_tag="TV191_000001"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEL1506559.1"
                     /translation="MTAQTPIHVYSEIGKLKKVLLHRPGKEIENLMPDYLERLLFDDI
                     PFLEDAQKEHDAFAQALRDEGVEVLYLETLAAESLVTPEIREAFIDEYLSEANIRGRA
                     TKKAIRELLMSIEDNQELIEKTMAGVQKSELPEIPAAEKGLTDLVESSYPFAIDPMPN
                     LYFTRDPFATIGTGVSLNHMFSETRNRETIYGKYIFTHHPIYGGGKVPMVYDRNETTR
                     IEGGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKQNLGFKKVLAFEFANNRKFMHL
                     DTVFTMVDYDKFTIHPEIEGDLRVYSVTYENEELRIVEETGDLAELLAANLGVERVEL
                     IRCGGDNLVAAGREQWNDGSNTLTIAPGVVVVYNRNTITNAILESKGLKLIKIHGSEL
                     VRGRGGPRCMSMPFEREDI"
     gene            1439..1870
                     /locus_tag="TV191_000002"
     CDS             1439..1870
                     /locus_tag="TV191_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1506560.1"
                     /translation="MTRVIVGNQPFQRAASLYIRYQVFVLERQIDRQDEFDCFDDNDR
                     VYAVLYDGDQPVSTARFLPTAKDQARLTRVATLRQYRGRGYGAQVIEALEQYAREQAY
                     ERLVIHSEISAQSFYEGLGYQAFGEPYDEDGEPCQSVEKYL"
     gene            1885..2898
                     /gene="argF"
                     /locus_tag="TV191_000003"
     CDS             1885..2898
                     /gene="argF"
                     /locus_tag="TV191_000003"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000195397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEL1506561.1"
                     /translation="MTQVFQGRSFLAEKDFTREEFEYLIDFAAHLKDLKKRGIPHHYL
                     EGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMF
                     DGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVKENFGKLEGLTLVY
                     CGDGRNNVANSLLVAGTLLGVNVHIFSPKELFPAEDIVKLAEGYAKASGAHVLVTDNA
                     DEAVKGADVLYTDVWVSMGEEDKFEERVKLLKPYQVNMELVKKAANDNLIFLHCLPAF
                     HDTNTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLFI
                     PKV"
     gene            3060..4553
                     /locus_tag="TV191_000004"
     CDS             3060..4553
                     /locus_tag="TV191_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEL1506562.1"
                     /translation="MTEEKKRGFKIPSSYTVLFIIIAIMAVLTWFIPAGAYETAKDGG
                     VISGTYQTVKSNPQGFFDILMAPVRGMLGVKGTEGAIQVSFFILMVGGFLRVVNKTGA
                     LDTGIASVVRKNKGREKLLIAILIPLFALGGTTYGMGEETMAFYPLLIPVMIAVGFDS
                     IVAVAIILIGSQIGCLASTINPFATGVAADAAGVSIADGMIWRIIQWVVLVGMSIWFV
                     YSYASKIEKDPSKSLVADKAEEHKEFFQLQNSGEDLTSRQRKVLAIFTLTFVIMILSL
                     IPWEDFDIQLFTNINTWLTTTPVLGGIIGKTMGAFGTWYFPEITMLFIMMGVLVAVVY
                     RMSEDDFFSAFLSGAGEFLGVAIICAVARGIQVIMNGGMITATILHWGETGLAGLSSQ
                     VFVVLAYIFYLPMSFLIPSTSGLAGATMGIMAPLGQFSNVPAHLVITAFQSASGILNM
                     ISPTSAIVMGALALGRIDLGTWWKFIGKFIVMVMLVSVLLLVVATFF"
     gene            4570..5901
                     /locus_tag="TV191_000005"
     CDS             4570..5901
                     /locus_tag="TV191_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEL1506563.1"
                     /translation="METYIQPRHQEACVAAIKKIVSYPSVLNEGENDTPFGQAIQDVL
                     EATLALCQDLGFNTYIDPKGYYGYAELGDQTEVLAILCHLDVVPAGDLKLWHKDPFTC
                     IEKDGCLYGRGTQDDKGPSMMALFATKALMDAGVVFNKRIRFIFGTDEETLWRCMNRY
                     NEVEEEATFGFAPDSSFPLTYAEKGLLQAKLVGKGSPKLNLEVGQAYNVVPARASYQG
                     DKLEALKEELDRLGFEYVVKDDELTVYGLAQHAKDAPDGINALIRLAKALVVLEPEPV
                     LDFLAHVVDEDGRAVNIFGPVQDEPSGGLSFNVAGLTLTKEMTEIRLDIRIPVLADKD
                     TLVDQLSQKAQDYGLAYEEFDYLAPLYVPLDSELVTTLLEVYRKKTGDQSPAQSSGGA
                     TFARTMANCVAFGALFPDAVQTEHQENEHIVLADAYRAMDIYAEAIYRLTR"
     gene            5919..6869
                     /gene="arcC"
                     /locus_tag="TV191_000006"
     CDS             5919..6869
                     /gene="arcC"
                     /locus_tag="TV191_000006"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEL1506564.1"
                     /translation="MTKQKIVVALGGNAILSTDASAKAQQEALVSTSKSLVKLIKEGH
                     EVIITHGNGPQVGNLLLQQAAADSEKNPAMPLDTCVAMTEGSIGFWLVNALDNELQAQ
                     GITKEVAAVVTQVIVDENDPAFKNPTKPIGPFLTEEDAKKQMAESGASFKEDAGRGWR
                     KVVPSPKPIGIKEANVIRSLVDSGVVVVSAGGGGVPVVKDPASKTLTGVEAVIDKDFA
                     SQTLSELVDADLFIVLTGVDNVYVNFNKPDQRKLEEVTVSQMKEYIAQDQFAPGSMLP
                     KVEAAIAFVENKSNAKAIITSLENIDNVLSANAGTQIIAG"
     gene            7089..8081
                     /locus_tag="TV191_000007"
     CDS             7089..8081
                     /locus_tag="TV191_000007"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEL1506565.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLIAKLDVVEVQGPILSRVGDGM
                     QDNLSGVENPVSVHVLNIPNATFEVVHSLAKWKRHTLARFGFNEGEGLVVNMKALRPD
                     EDSLDQTHSVYVDQWDWEKVIPDGQRNLAYLKETVETIYKVIRLTELAVEARYDIEAV
                     LPKKITFIHTEELVARYPDLTPKERENAITKEFDAVFLIGIGGVLPDGKPHDGRAPDY
                     DDWTSESENGYHGLNGDILVWNEQLGTAFELFSMGIRVDEEALKRQVDITGDQERLQF
                     DWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKKHIGEVQTSVWPQEVRDTYDNIL"
     gene            8253..8792
                     /gene="rsmD"
                     /locus_tag="TV191_000008"
     CDS             8253..8792
                     /gene="rsmD"
                     /locus_tag="TV191_000008"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEL1506566.1"
                     /translation="MRIVSGEFGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFKGGR
                     VLDLFAGSGGLSIEAISRGMSEAVLVERDRKAQAIIQANIKMTKASQQFTLLKMNAER
                     ALDHLSGQFDVVFLDPPYAKETIVANIEALVEKNLLSDDVMIVCETDRSVALPEAIAW
                     LGIWKEKQYGISKVTVYVR"
     gene            8782..9282
                     /gene="coaD"
                     /locus_tag="TV191_000009"
     CDS             8782..9282
                     /gene="coaD"
                     /locus_tag="TV191_000009"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEL1506567.1"
                     /translation="MSGKIGLYTGSFDPVTNGHMDMIKRASHLFEHVYVGIFNNPNKQ
                     SFFTFELRAQMLSEAVCALPNVTVVSAEHGLAVDLARELSVTHLIRGLRNTADFDYEI
                     GLEYFNHRLAPDIETIYLMATHDLQPVSSSRIRELIAFRAPITGLVPQAVINQVEKMN
                     ENNKKN"
     gene            9260..10297
                     /locus_tag="TV191_000010"
     CDS             9260..10297
                     /locus_tag="TV191_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEL1506568.1"
                     /translation="MKTIKKIKWWLIGFVALLFLLLTLFFPLPYYIEMPGGAYDIRSV
                     LTVNGKEDKEKGAYQFVVVSLSRATLAKLLYAWLTPFTEISTMEDTTGGYSDADYLRI
                     NRFYMETSQNSAVYQALTLAGKEVSFDYKGVYVLDVSKDSSFKGVLHLADTVTGVNGK
                     TFTTSADLIDYVSHLTLGDEVQVQFTTAGESKTEKGKIIKLKNGKNGIGITLTDHTQV
                     ISGDEVDFSTGGVGGPSAGLMFTLDIYDQINHEDLRKGRVIAGTGTIGKDGKVGDIGG
                     AGLKVAAAAAAGADIFFVPNNPVHKDVKKANPKAISNYEEAKKAAKRLKTAMKIIPVK
                     TVQDAISYLKK"
     gene            10859..11473
                     /locus_tag="TV191_000011"
     CDS             10859..11473
                     /locus_tag="TV191_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEL1506569.1"
                     /translation="MKRDILPEMYNYNKFPGPEFIHFDHYVKAEGIELLLLKNEKNAF
                     NTTSFGQRFTEILLKYDYIVGDWGNEQLRLKGFYKDHHDVKKASRISRLEDYIKEFCN
                     FGCAYFVLENPNPKDMPKEEERPSRRRKSSKANRRRNQPQHSQQAPAKDNFKKLTKDR
                     SADKPSFTSKKRPAPNKTKGNQRRSRTSQLNHKTDHFIIRKKDN"
     gene            11477..12559
                     /gene="rlmN"
                     /locus_tag="TV191_000012"
     CDS             11477..12559
                     /gene="rlmN"
                     /locus_tag="TV191_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEL1506570.1"
                     /translation="MKPSIYGLTRDELIAWAIDNGQKAFRATQIWDWLYRKRVQSFDE
                     MTNISKEFVAILKDSFCINPLKQRVAQESADGTVKYLFELPDGMLIETVLMRQHYGQS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNSGEITAQIMMVQNYFDKRAQDERVSHVVVM
                     GIGEPFDNYQNVMTFLRTINDDHGLAIGARHITVSTSGLAHKIREFANEGVQVNLAVS
                     LHAPNNELRSSIMRINRSFPLDKLFSAIEYYIETTNRRVTFEYIMLNKVNDGVEQAQE
                     LADLTKRIRKLSYVNLIPYNPVSEHDQYSRSPKERVAAFYDILKKNGVNCVVRQEHGT
                     DIDAACGQLRSNTMKKDRQKAAAART"
     gene            13841..14371
                     /locus_tag="TV191_000013"
     CDS             13841..14371
                     /locus_tag="TV191_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEL1506571.1"
                     /translation="MTNTLVENIYASVTHNISKKEASKNEKTKAVLNQAVADLSVAAS
                     IVHQVHWYMRGPGFLYLHPKMDELLDRLNANLDEMSERLITIGGAPYSTLEEFSQHSK
                     LDETKGSYDKSVAQHLARLVEVYLYLTSLYQVGLDITDEEGDAASNDLFTAAKADAEK
                     TIWMLQAERGQGPAIF"
     gene            14744..14977
                     /locus_tag="TV191_000014"
     CDS             14744..14977
                     /locus_tag="TV191_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEL1506572.1"
                     /translation="MKTLYDVQQLLKGFGIVIYMGKRLYDIEMMKIELQRLYDGGLLD
                     KQAYLTAELILRREHRLELKREGQENESKIDRD"
     gene            14952..15923
                     /locus_tag="TV191_000015"
     CDS             14952..15923
                     /locus_tag="TV191_000015"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEL1506573.1"
                     /translation="MSQKLIGIDLGGTTIKFGILTSEGDVQEKWAIETNVLEDGKHIV
                     PDIVASLKHRLDLYGLTKDDFIGIGMGSPGAVNRTDHTVTGAFNLNWRGTQEVGSVIE
                     RELGIPFAIDNDANVAALGERWVGAGDNNPDVVFMTLGTGVGGGIIADGNLIHGVAGA
                     GGEIGHMIVEPLKGFACTCGSQGCLETVASATGVVKVARLLAEAYEGDSSIKAAIDNG
                     EAVSSKDIFVAAEAGDAFANSVVEKVSYYLGLAAANISNILNPDSVVIGGGVSAAGEF
                     LRSRVEKYFMTFTFPQVRQSTKIKIAELGNDAGIIGAASLARQFITE"
     gene            15933..16313
                     /locus_tag="TV191_000016"
     CDS             15933..16313
                     /locus_tag="TV191_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEL1506574.1"
                     /translation="MSPLTMIGWVLLAGVIAYYLWNYVSYRRMAKQVDNDTFKELMRQ
                     GQVIDLRDPASFRARHILGARNFPAQQFTTSIKALRKDKPILLYENVRPQYRVKAVKT
                     LRKAGYTDLYVLKAGLDYWNGKVK"
     gene            16709..18550
                     /gene="typA"
                     /locus_tag="TV191_000017"
     CDS             16709..18550
                     /gene="typA"
                     /locus_tag="TV191_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEL1506575.1"
                     /translation="MTKFREDIRNVAIIAHVDHGKTTLVDELLKQSHTLDERKELQER
                     AMDSNDLEKERGITILAKNTAVAYNDVRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQNLTPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LEFPVVYASAINGTSSLSDDPADQEKTMAPIFDTIIDHIPAPVDNSAEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERKEIQEAKAG
                     DLIAVSGMEDIFVGETITPTDCVEALPVLRIDEPTLQMTFLVNNSPFAGREGKWVTSR
                     KVEERLLVELQTDVSLRVEPTESPDKWIVSGRGELHLSILIETMRREGYELQVSRPEV
                     IIKEIDGVKCEPFERVQIDTPEEYQGAIIQSLSERKGDMLDMQMVGNGQTRLIFLIPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPVVAGEIGGRHRGALVSIENGKATTYSIMR
                     IEERGTIFVNPGTEVYEGMIVGENSRDNDLGVNITTAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAARDKANKKKKSAE"
     gene            18632..18886
                     /locus_tag="TV191_000018"
     CDS             18632..18886
                     /locus_tag="TV191_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEL1506576.1"
                     /translation="MFYLIIAALITSYYLFMAPKSVRNTLGMIGLVGLVALLIVLAGL
                     SFIKIMQTPKEIFVGLAMIVLGYYALRDIQKIPKKPKSKH"
     gene            19032..20393
                     /locus_tag="TV191_000019"
     CDS             19032..20393
                     /locus_tag="TV191_000019"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEL1506577.1"
                     /translation="MKTITEFQNKKVLILGLAKSGEAAARLLARLGAIVTVNDSKPFE
                     ENPAAQALLEEGIRVICGSHPLELLDEDFYCMVKNPGIRYDNPMVVRALDKAISILTE
                     VELAYLVSEAPIIGITGSNGKTTTTTMIADVLNAGNHSALLAGNIGFPASEVAQAATA
                     KDILVMELSSFQLLGTEQFQPHIAVITNLVPTHLDYHGSFEDYIAAKWRIQHRMTDKD
                     YLVLNADQELVKSLAQKTKASPVFFSTKEKVDGAYLADGYLYFKEERLMSAAELGVPG
                     RHNIENALATIAVAKLRGISNQVISRTLSHFRGVKHRLQLVGTLNQVTFYNDSKSTNI
                     LACQKALSGFDNSKVILIAGGLDRGNEFDELVPDLVGLKKMILLGESAERMKRAADKA
                     GVSYLDAKDVAAATKIAFEQAKAGDIILLSPANASWDMYPSFESRGDEFLAAYDALKG
                     EAQ"
     gene            20390..21472
                     /locus_tag="TV191_000020"
     CDS             20390..21472
                     /locus_tag="TV191_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEL1506578.1"
                     /translation="MTKKIIFTGGGTAGHVTLNLILIPKFIKDGWEVHYIGDDKGIEH
                     QEIKKSGLDVTFHAIATGKLRRYFSWQNLLDIFKVGFGVMQSLFIIARLRPKALFSKG
                     GFVSVPPVIAARLLGVPAFIHESDLSMGLANRIAYRFATTMYTTFEQEQTLAKLKHVG
                     AVTKVTGPGSRSVTSKQLEAVLEYFDPNLKTLLFIGGSAGARVFNRFITDHPELKEDF
                     NIINISGDPSLNELSWHLYRVDYVTDLYQPLMEMADLVVTRGGSNTLFELLAMRKLQL
                     IIPLGKEASRGDQLENAHYFTTRGYAEQLLEQELTLPHFQEKVREVFAKQSDYLSAMK
                     SSSELQSPESFYQLLSADISSATKEN"
     gene            21473..22663
                     /locus_tag="TV191_000021"
     CDS             21473..22663
                     /locus_tag="TV191_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HEL1506579.1"
                     /translation="MADKTKHSEEKAALTEWQKRNIEFLNKKQQQAEKDKKLKEKLLN
                     EKIAQAQGEAASKADQEDTDEAEEKTEVSQAGTDEGEPLPEASEQEVPSPKDKPLKVP
                     KEKSPKQQALQKGWPVLLVSFVVLCLSIFMITPYSKVKDFSVKGNKKTSVEDLVRDSG
                     IKSSDYWITLLASPGSYENAVLKANPWVKKVALRYGFPNHFRFDVTEFDIIAYAQVAE
                     GFQLILENGKRVAAVKQAALPKSFLILNLEHEKEIQDVINRLTKIPSDLVKAIKSVSS
                     ANSQTTKDLLLLEMHDGNLIRVPRSQLELKLPYYQKIKKNLDTASIVDMEVGIYTTTA
                     EIENMPEVPASAQASQADKPAEASPEQGEEQATQEQPSPETPANPEATNPSVAQPTEQ
                     ANQQ"
     gene            22875..24239
                     /gene="ftsA"
                     /locus_tag="TV191_000022"
     CDS             22875..24239
                     /gene="ftsA"
                     /locus_tag="TV191_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEL1506580.1"
                     /translation="MARNGFFTGLDIGTSSIKVLVAEFISGEMNVIGVSNVPSTGVKD
                     GIIIDIEAAAAAIKTAVEQAEEKAGMTIERVNVGLPANLLQIEPTQGMIPVPSESKEI
                     KDEDVDSVVKSALTKSITPEREVISLVPEEFIVDGFQGIRDPRGMMGIRLEMRGLIYT
                     GPSTILHNLRKTVERAGIKVENIIISPLAMAKAVLNEGEREFGATVIDMGGGQTTVAS
                     MRAQELQYTNIYAEGGEYITKDISKVLKTSMSIAEALKYNFGQADMAEASLTDTVKVD
                     VVGSDEPVEVTERYLSEIISARVRHILDRVKQDLERGRLLDLPGGIVLIGGGAIMPGV
                     VEVAQEIFGTNVKLHIPNQVGIRNPMFANVISLVEYVGMMSEVDVLAQNAVSGEELLR
                     RKPIDFTGQEAYLPDYNETRGFEPAPNYEQQVPQADYEPQEPAEPKQKISERVRGIFG
                     SMFD"
     gene            24263..25591
                     /gene="ftsZ"
                     /locus_tag="TV191_000023"
     CDS             24263..25591
                     /gene="ftsZ"
                     /locus_tag="TV191_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEL1506581.1"
                     /translation="MAFSFDTASIQGAIIKVIGVGGGGGNAINRMIDEGVAGVEFIAA
                     NTDIQALSSSKAETVVQLGPKLTRGLGAGGQPEVGRKAAEESEEVLTEALTGADMVFI
                     TAGMGGGSGTGAAPVIARIAKSLGALTVAVVTRPFGFEGNKRSNFAIEGIQELREQVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITSPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERIVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDMTLTEA
                     EEASEIVGQAAGQGVNIWLGTSIDDSMRDEIRVTVVATGVRQDKAEQASGFRQPRTYT
                     QSNAQQAAGAQYASEQVRQTAQPSFDRRSSSFDFDMGETREMPKSQQAMPAHGHNHNQ
                     GSAFGNWDLRRDNIARPAEGELDNQLNMSTFSSNDDIDDELETPPFFKNR"
     gene            25594..26265
                     /locus_tag="TV191_000024"
     CDS             25594..26265
                     /locus_tag="TV191_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEL1506582.1"
                     /translation="MDLQKNKDIVFENIRLATQAANRPENSVSVIAVTKYVDKAVAGQ
                     LIDMGIEHIAENRIDKFLDKYEALKDRQVTWHFIGTLQRRKVKEVINKVDYFHALDSV
                     KLALEIEKRADHPVKCFLQVNISEEESKHGFKIAELDAAIEEISKMEKLHLVGIMTMA
                     PIDASQQELRSIFQKANQLRKNLQSKKRKNMPFTELSMGMSNDYPIAIQEGSTFVRIG
                     TSFFH"
     gene            26278..26940
                     /locus_tag="TV191_000025"
     CDS             26278..26940
                     /locus_tag="TV191_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEL1506583.1"
                     /translation="MAIKDAFNKMISYFDTDGVSEVEEELSSKKQEEPVTKSQQTSRP
                     NQQQQAARASQPQQPKQARPQMQAQQRPQSQSRAAYAERPYQGQSQARVSHDYNDRRA
                     TSAPSASSRREQYQHAAHQEQTTIALKYPRKYEDAQEIVDLLIVNECVLIDFQYMLDA
                     QARRCLDFIDGASKVLYGTLQRVGSSMYLLTPSNVSVNIEEMNIPNNGQDIGFDFDMK
                     RR"
     gene            26945..27202
                     /locus_tag="TV191_000026"
     CDS             26945..27202
                     /locus_tag="TV191_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEL1506584.1"
                     /translation="MIFILLILLKLIKVYSYLLLVYALLSWFPGAYDSWLGRLVSDIV
                     EPILKPFRSLNLQFAGLDFTIYLVMIGLNVLSEILIRVLIS"
     gene            27199..27993
                     /locus_tag="TV191_000027"
     CDS             27199..27993
                     /locus_tag="TV191_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEL1506585.1"
                     /translation="MTVQTMLYQHFQPDEHPFIERMLDLIARVEANYLLEVTDFLNPR
                     EVTILKGLVAATNLQCFSSTDYYPSEYGRVIVAPDYYCLDKADFDLALIEVTYNAKFN
                     QLTHAQILGTLINELGIKRALLGDIFVEIGHAQVMINRQLLSYCLGTIAKIAKARVKL
                     KEIDLDQLLNLTANQQVLTDIMVSSLRVDRLIATVLKQSRNQAIRLVEAGKVKVNYQL
                     VTKASQPVAVGDLISIRGYGRFSILTDNGFTKNGKYKLTLSKMMRK"
     gene            28003..28758
                     /locus_tag="TV191_000028"
     CDS             28003..28758
                     /locus_tag="TV191_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HEL1506586.1"
                     /translation="MALTALEIKDKTFKTKFRGYSEEEVNEFLEIVVDDYEALVRKNR
                     DNEAKIRELEEKLSYFDEMKESLSQSVILAQETAEKVKSSANAEATNLVSKATYDAQH
                     LLDESKAKANQLLRDATDEAKRVAIETEELKRQTRVFHQRLVSAIESQLSLSNSPEWD
                     ELLQPTAVYLQNSDAAFKEVVKTVLNEDIPEADDSNSFDATRQFTPEELEELQRRVEE
                     SNKELEAYQVQREEQASEPEVNLSETQTFKLNI"
     gene            29029..31827
                     /locus_tag="TV191_000029"
     CDS             29029..31827
                     /locus_tag="TV191_000029"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEL1506587.1"
                     /translation="MKLKETLNLGKTAFPMRAGLPNKEPQWQKAWDEAEIYKKRQALN
                     EGKPAFHLHDGPPYANGNIHVGHALNKISKDIIVRAKSMSGYQAPFVPGWDTHGLPIE
                     QVLAKQGVKRKEMDLADYLDMCRQYALSQVDKQRDDFKRLGVSADWDNPYVTLDPSFE
                     ADQIRVFGAMADKGYIYRGAKPVYWSWSSESALAEAEIEYHDIDSTSLYYANRVKDGK
                     GILDTDTYVVVWTTTPFTVTASRGLTVGPDMDYVVVRPAGSDRNYVVAEGLLDSLAAK
                     FAWESFEILANHKGSDLEYIVTEHPWDSEVDELVILGDHVTLDSGTGIVHTAPGFGED
                     DYNVGMTYGLEVAVTVDERGLMMENAGPDFHGQFYGKVTPIVIEKLGDLLLAQEVINH
                     SYPFDWRTKKPIIWRAVPQWFASVSDFRQEILDEIDKTTFHPTWGKTRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTKEVTDHVADLFQEHGSIIWWQKEAKELLPEGF
                     THPGSPNGVFTKETDIMDVWFDSGSSWNGVMNARDHLAYPADLYLEGSDQYRGWFNSS
                     LITSVAVNGHAPYKAILSQGFVLDGKGEKMSKSKGNIISPNDVAKQYGADILRLWVAS
                     VDTDNDVRVSMDILGQVSETYRKIRNTLRFLLANTSDFNPHTDKVAYAELAAVDKYMT
                     IKFNKLVGAINTAYERYDFMTIYKAVVNFVTVDLSAFYLDFAKDVVYIEAANSLARRR
                     MQTVFYDILVNITKLLTPILPHTAEEIWSYLEHEPEDFVQLSELPQAQTFDNQDTILE
                     EWEAFMTLRAQAQKALEEARHDKIIGKSLEAHLTIYASPEVKTLLTALDSDIALLLIV
                     SQLTISEEPAPENAVSFDDVAFTVARAQGEVCERSRRIDPTTRMRSYNAFVCDHSAKI
                     IEENFPEAVAEGFDSAAN"
     gene            complement(32305..32607)
                     /locus_tag="TV191_000030"
     CDS             complement(32305..32607)
                     /locus_tag="TV191_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEL1506588.1"
                     /translation="MRLINTTSSHPELVRNQLQNTDAHLVEVYSAGNTDVIFTQAPKH
                     YELLISNKYRAIKEDELEVIREFFLKRKIDQSIVIPGHSKTLHTNNLIEISFQTSV"
     gene            complement(32669..33118)
                     /locus_tag="TV191_000031"
     CDS             complement(32669..33118)
                     /locus_tag="TV191_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL1506589.1"
                     /translation="MTVPIFGDKIDDQHYTARYGVYAVIPNSAKTEIILVQAPNGAWF
                     LPGGEIEAGESQLQALERELVEELGFAADIGYYYGQADEYFYSRHRDTYYYNPAYLYE
                     VTSFQAISKPLEDFNHLAWFLPIADAITVLKRDSHRWGVEEWQKKHH"
     gene            complement(33278..35530)
                     /locus_tag="TV191_000032"
     CDS             complement(33278..35530)
                     /locus_tag="TV191_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEL1506590.1"
                     /translation="MLCQNCNLNESTIHLYTSINGKQRQIDLCQNCYQIMKTDPKNPI
                     LGGYNGNQKAQQPSQNPFFDDFFGDLNNFRAFGQLPNTPPTQSGGHNGGGHNGYRPNH
                     TQPAQEANKGLLEEFGINITEMAKRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGE
                     PGVGKTAVVEGLAQKIVDGDVPQKLQSKQVIRLDVVSLVQGTGIRGQFEERMQKLMEE
                     IRKRHDVILFIDEIHEIVGAGAVGDGSMDAGNILKPALARGELQLVGATTLNEYRIIE
                     KDAALERRMQPVKVDEPSVEETITILKGIQPKYEDYHHVKYSQSAIEAAANLSNRYIQ
                     DRFLPDKAIDLLDEAGSKMNLTLNFVDPKDIDKRLIEAENLKTQATRDEDYERAAYFR
                     DQIAKYKEMQAQKLDEQDIPIITDKTIEAIVEQKTNIPVGDLKEKEQSQLVNLAADLK
                     KHVIGQDDAVDKIAKAIRRNRVGLGAPNRPIGSFLFVGPTGVGKTELSKQLAIELFGS
                     ADNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPYSLILLDEIEKAH
                     PDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKTEASVGFGAAREGRTNS
                     VLGELSHFFSPEFMNRFDGIIEFQPLSKDNLLHIVHLMLDDVNHRLAHNNIRLDVTQK
                     VKEKLVELGYDPKMGARPLRRTIQDYIEDAITDFYLEHPAEKDMRAVLTSNGHIIIKP
                     VVKSQAKQAD"
     gene            35812..36042
                     /locus_tag="TV191_000033"
     CDS             35812..36042
                     /locus_tag="TV191_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003105222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1797 family protein"
                     /protein_id="HEL1506591.1"
                     /translation="MESHLVRIINRLELMVTDGGNLKRNFERDGVVVAEVAFVNDPEN
                     GPVFILRDIEARESYSFDSIDLIAMEIYDLLY"
     gene            complement(36524..37462)
                     /locus_tag="TV191_000034"
     CDS             complement(36524..37462)
                     /locus_tag="TV191_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1506592.1"
                     /translation="MKKTIRKYSVCSAAIALATMASLGTAGNARAEDYTRLESYPDPA
                     ELIRDGLGDGEVRVYLHTLRQFMQTYLQNLELQAKKGGPQGPVGPAGPRGERGEQGPV
                     GPMGPRGDKGETGETGPKGEQGPAGPKGDRGERGEKGEQGQRGEKGEQGQRGEKGEQG
                     QRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGE
                     KGEQGQRGEKGEQKPKGDQGKDTKPSAPKAPEKTPAPKAPEKSAQPKAPAPKSAPAAQ
                     KSTLPATGETNHPFFTLAALSVITSAGVLNLKKKKS"
     gene            37804..38487
                     /locus_tag="TV191_000035"
     CDS             37804..38487
                     /locus_tag="TV191_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL1506593.1"
                     /translation="MDFTFLPKYWAYFNYGVLVTMMISACVVFFGTIIGLLVTLIKRS
                     HIKPLSWLVSLYVWIFRGTPMVVQIMIAFAWLHFNDLPIVGFGVLDLDFSRLLPGIII
                     ISLNSGAYISEIVRAGIEAVPKGQLEAAYSLGIRPKNAMRYVILPQAFKNILPALGNE
                     LITIIKDSALLQTIGVMELWNGAQSVVTATYLPITPLLFAAFYYLMITTILSQLLGCL
                     ERKLAQGGR"
     gene            38489..39226
                     /locus_tag="TV191_000036"
     CDS             38489..39226
                     /locus_tag="TV191_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1506594.1"
                     /translation="MTETVISIRQLHKSFGKHEVLKGIDLTINQGEVVVIIGPSGSGK
                     STLLRTMNLLEVPTKGHISFEGVDITDKANDIFKMREKMGMVFQQFNLFPNMTVLENI
                     TLSPIKTKGMSRAGAEQRAYELLERVGLRDKAAAYPASLSGGQQQRIAIARGLAMDPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAKEVADRVIFMDGGLV
                     IEEGSPVQVFEAPKEERTKDFLSKVLS"
     gene            39670..41364
                     /locus_tag="TV191_000037"
     CDS             39670..41364
                     /locus_tag="TV191_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEL1506595.1"
                     /translation="MDYKAVYQEWLHNDFFNEEIKADLEAIKHDEAEIQDRFYKVLEF
                     GTAGLRGKLGAGTNRMNIYMVGKAAQALANTIIDHGPEAVSRGIAISYDVRYKSKEFA
                     ELTCSIMAANGIKSYIYKGIRPTPMCSYAIRALNCISGVMITASHNPQAYNGYKAYWE
                     EGSQILDDIANQIAVHMDAIERFEDVKQIPFEEALASGLTSYIDDSIEEAYKKEVLGL
                     TINDTDIDKSVRVVYTPLNGVGNLPVREVLKRRGFDHVFVVPEQEMPDPDFTTVGYPN
                     PEVPKAFAYSERLGQEVGAAILIATDPDCDRVALEVRAADGSYVFLNGNKIGALLSYY
                     IFSQRHARHNLPDNPVLVKSIVTGDLSKAIAAKYDVETVETLTGFKNICGKANDYDIT
                     KEKTYVFGYEESIGFCYGTFVRDKDAVSASMMVVEMAAYYKQRGQSLLDVLQDIYKEF
                     GYYNERQVALELEGVEGQKRIARIMEDFRNEPIEHAGAMSLKTIVDFKDGYLDFPKQN
                     CLKYYFDDGSWYALRPSGTEPKIKLYIYTIGETEADSIAKLDAIESACQAKMDSVS"
     gene            41476..42330
                     /locus_tag="TV191_000038"
     CDS             41476..42330
                     /locus_tag="TV191_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEL1506596.1"
                     /translation="MVQIIDGKALAQKMQAALAKKVESLKAEKGIVPGLVVILVGDNP
                     ASQVYVRNKERAALAAGFKSETVRLSDSVCQEELIELIEQYNQDDTIHGILVQLPLPH
                     HINDKSIILAIDPKKDVDGFHPMNTGHLWSGRPNMVPCTPAGIMEMFHDYGIELEGKN
                     AVIVGRSNIVGKPMAQLLLDKNATVTLTHSRTRRLADICRRADILIVAIGQGHFITKE
                     FVKEGAVVIDVGMNRDVNGRLIGDVAFDEVSELASMITPVPGGVGPMTITMLLEQTYQ
                     AALRRVSQ"
     gene            42327..43181
                     /locus_tag="TV191_000039"
     CDS             42327..43181
                     /locus_tag="TV191_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEL1506597.1"
                     /translation="MIIDQSFVARVVVPRQADSHKGSYGRVLLVGGLYPYGGAIIMVA
                     LACVHSGAGLVTVATDRETIAALHSHLPEAMAIAVDDEELLLSQLGMADLILIGPGLS
                     ENSRAARLFELVLAHVADHQVLVIDGSALRLLAKRAADVKQLRCPLVLTPHQKEWEAL
                     SGLAIDQQYDAANQAALKHFPRATILVAKSSATKIYHGNQIYRLRVGGPYQATGGMGD
                     TLAGMIAGIAVQFPESSLVAKVACATYLHSAIADELAKTAYVVLPTAISYELPRWLKA
                     ISTGQKLG"
     gene            43465..44805
                     /locus_tag="TV191_000040"
     CDS             43465..44805
                     /locus_tag="TV191_000040"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEL1506598.1"
                     /translation="MADYLSVTQLTKYLKLKFDRDPYLERVYLTGQVSNFRKRPNHQY
                     FSLKDEGAVIQATMWAGAYKKLGFDLEEGMKLNVVGRIQLYEPNGSYSMIIEKAEPDG
                     IGALALQFEQLRQKLAGEGFFDERHKQALPQFVTKVGIVTSPSGAVIRDIITTISRRF
                     PGVSILLFPTKVQGEGAAQEVAANITKANQREDLDLLIVGRGGGSIEDLWAFNEEIVV
                     QAIFESRLPVISSVGHETDTTLADFVADRRAATPTAAAELATPITKTDIVSWIAEQQS
                     RSYQACLRYIRQGQERVDKLSYSVIFRQPERLYDAYSQRLDRLTTSLMTTFKETLSGA
                     KQEHLILEHRLASVNVQARLERYQDRLATAHRLLIANMTNQYDSKLAGFERAQAALLS
                     LDTSRIIARGYALLKKDGVVAACVKDIKKGDHLSIIMRDGQLEVEVEDVNEKNI"
     gene            44783..44998
                     /locus_tag="TV191_000041"
     CDS             44783..44998
                     /locus_tag="TV191_000041"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEL1506599.1"
                     /translation="MSTKKIFEERLQELEAIVTRLENGDVPLEEAISEFQKGMVLSKD
                     LQKTLQAAEKTLVKVMQADGTELEMDA"
     gene            44998..45867
                     /locus_tag="TV191_000042"
     CDS             44998..45867
                     /locus_tag="TV191_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEL1506600.1"
                     /translation="MDKLTRINATIHQYYDRQSTVSADLEEAILYSVDGGGKRLRPLM
                     LLELLEGFGLALTDAHYAVAAAVEMIHTGSLIHDDLPAMDNDDYRRGRLTSHKQFNEA
                     TAILAGDSLFLDPFALIAGADLPADLLVQLIQQFSLASGTFGMVGGQLLDMKGEHQLL
                     DIQELSDIHANKTGKLLTLPFVAAGIIAEQSADVLSCLWEAGRLVGQAFQIRDDILDL
                     TASFADLGKTPQKDLAAAKSTYPSLLGLERSRAILEESLSQALAIFSRLEREEGFESQ
                     AIIKRIEGLRLNG"
     gene            45860..46687
                     /locus_tag="TV191_000043"
     CDS             45860..46687
                     /locus_tag="TV191_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEL1506601.1"
                     /translation="MAKERVDVLAYRQGLFETREQAKRGVMAGLVISAISGLRFDKPG
                     EKIDEGIELRLKGEKLKYVSRGGLKLEKALQVFGISVQDKVTIDIGASTGGFTDVMLQ
                     AGARLVYAVDVGTNQLVWKLRQDSRVRSMEQYNFRYAKLADFSEGQPAFASIDVSFIS
                     LSLILPTLHCILQEGAEAVALIKPQFEAGREQIGKKGIVKDRLIHEKVIKQVADTALN
                     CGFIVKGLDFSPIQGGHGNIEFLAHLVKGKGSKAIDDQLIQSVVSSAHKEFKQHEKE"
     gene            46674..47144
                     /locus_tag="TV191_000044"
     CDS             46674..47144
                     /locus_tag="TV191_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEL1506602.1"
                     /translation="MKKSERLDLIKKMVLSHEIETQHELLKLLADYGLELTQATISRD
                     MNEIGIVKIPSGTGRYVYGLSQDSGKRVVQRPASIKKTILEMSEKTAGLEQHIHLNVV
                     PGNSKLIKRYLMTDFSGQLFSLIADDDSLLLIAKSEADADHIRQELSLWMQGLV"
     gene            47162..48823
                     /gene="recN"
                     /locus_tag="TV191_000045"
     CDS             47162..48823
                     /gene="recN"
                     /locus_tag="TV191_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEL1506603.1"
                     /translation="MLLEISIKNFAIIEEISLNFENGMTVLTGETGAGKSIIIDAMNM
                     LLGARASTEVIRHGADKAEIEGFFSVDANPHLAAVLAESGISMEEELILRRDIFANGR
                     SVSRINGQMVTVSTLKKLGQFLVDIHGQHDQEELMRPQLHQHILDSFGDEAFDQLKQS
                     YQQIFDRYKALRRQALEKQKNEKEHQARLDLLAFQIGEIEAADLVRGEDDLLNQERQR
                     LLNHKKIADTLTSAYLSLDNEDFSSLSQVRSSMNELLSIEDLAPEYQLISAGVSEAYY
                     ILEEVTKQLSDTIDQLDFDAGRLQDIELRLDSINSLTRKYGGGVNDVLDYYANITKEY
                     QLLSGDDRSSDELERELKVLEKQLVMTASQLSDKRHALALELEADIKAELRELYMEKA
                     DFKVHFTRSKFNREGNESLEFYISTNPGEGFKPLVKVASGGELSRLMLAIKAAISKKE
                     DKTSIVFDEVDTGVSGRVAQAIAKKIYKIGSYGQVLAISHLPQVIAIADNQYFISKES
                     KEESTVSKAKLLTQEERIEEIAKMIAGADVTETARNQARELLGKD"
     gene            49044..49916
                     /locus_tag="TV191_000046"
     CDS             49044..49916
                     /locus_tag="TV191_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1506604.1"
                     /translation="MLKKRMGLASLLVLMTFVYQCCSVTAEQYSDTEVEVLQISEEKS
                     QIMENQEALKDLTTSSDQLKKEALKPKEAATNKSKQEASTVYLAEDDPVTIDSSDEES
                     NQDIIADSVPDLVIKGDQVDVSEVMVSVKEDSSKVAKQRTDAAQRYSIAKHQLTQKLE
                     AFNAATDQLLTMIAKKSDLTGQYYVVGHSLGEMLAAQNEKKLAEQLVMQQKHKKGLGS
                     SVTILDELGRVISDISGHKGMLPFNRKISFKVHQVRYDLPLTGDRTVLPAQLAGLLLL
                     LIGLMLPKVANKKS"
     gene            50054..50905
                     /locus_tag="TV191_000047"
     CDS             50054..50905
                     /locus_tag="TV191_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL1506605.1"
                     /translation="MELKMGTIKIVADSSMTIEPELIKSLDITVVPLSVMIDSKLYSD
                     NELKEEGQFLQLMRASKSLPKTSQPPVGLFADIYERLVKEGATAIVAIHLSPALSGTI
                     EASRQGAEIAAAPVTVLDSGFTDQALKFQVVEAARLAQAGASLEEILEAVEDIKRKTE
                     LYIGVSALEHLVKGGRIGRVTGLLSSLLNIRVVMEMKNDTLQTLVKGRGNKTFTKWLD
                     SYLAENSQRQIAEVAISYAGQRDFADSLKKTIATVFDGPITVLETGSIIQTHTGEGAF
                     AVMVRYE"
     gene            50898..51740
                     /locus_tag="TV191_000048"
     CDS             50898..51740
                     /locus_tag="TV191_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HEL1506606.1"
                     /translation="MNKRGFLGGLIFFFSVFALSFVILAVLIPKSDPQLKKSDFLKNK
                     KISLNYIAIGDSLTEGVGDLTNQGGFVPLLSGDLGDYFNATVNTENYGVSGNTSQQIL
                     TRMTENKEITEQLKKANLMTLTVGGNDVLAVIRKNLANLKVSSFKKPARQYQERLRKI
                     LDLARKDNQDLPIFVLGIYNPFYLNFQELTEMQTVINDWNKKTQEVVDDYDHVYFVPI
                     NDLLYKGVDGKEGIVQSTGEQTTIVNDALFSGDHFHPNNTGYQIMSDAVMETIRKNGK
                     EIKP"
     gene            51718..52305
                     /locus_tag="TV191_000049"
     CDS             51718..52305
                     /locus_tag="TV191_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HEL1506607.1"
                     /translation="MEKKLNLNWWKWAFLLLLAFNAAFLAVIGSRIIQIREPKSELIN
                     QKAAKNIKIGTLTTTKEQLNEAVVSYLKDFQTEKMTYKVYATSSTILFEGTYQLLGYE
                     VPLYIYFQPHRLTNGAIQLQVLSFSVGTLSLPEKDVLQYLKSSYKLPKFVEVLPKQSA
                     IIINLQQLENDANIYLKAQKIDLVKDDIRFDIYKK"
     gene            52403..52678
                     /locus_tag="TV191_000050"
     CDS             52403..52678
                     /locus_tag="TV191_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEL1506608.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVDAVFSAIEAFLAEGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIAASKVPAFKAGKALKDAVK"
     gene            complement(52739..53443)
                     /locus_tag="TV191_000051"
     CDS             complement(52739..53443)
                     /locus_tag="TV191_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosyltransferase"
                     /protein_id="HEL1506609.1"
                     /translation="MLVVQPSTIKAQSYDEGQTVVFEPYGNSFKPYYKFSEPDVTKYI
                     ITNRWRSQTAFTEAEKKMMYQYTYASASPINLALEQVMGDTSQLDAQLQQSVALLDSA
                     THKLTIPWNIIVYRYVYETFLTELGTSEEELARYYHDKTFDPQILSAIKPGTHYTKQG
                     FMSTTAIKNAAMPHRSVELRIQVPQGSQAAFVQPYSFYPYEMELLFPRQCTLEIIGAN
                     LSDDHTRLLIETRLLP"
     gene            complement(53754..54962)
                     /locus_tag="TV191_000052"
     CDS             complement(53754..54962)
                     /locus_tag="TV191_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1506610.1"
                     /translation="MRKNDYQLLASRAINKIGNTVYDYSNSSGIAGLGATGRQYLGYY
                     QLAEGLISLILNPIGGAIADRYKRRQLLLWTDAIGAISCGLLALIANPTIMLYGLITV
                     NALLAISYAFSGTAFRAYVVTLVETERLVHFNAQLEIVSQIISISSPMLAFLVMDCFG
                     IKTALALDSISFLLSFLCLYTIKDKERHITKQSSQGNRLQLLTDIKEGLQFIYHDNDI
                     FSLLIIASLVNFFIAAFNYLIPFSNQLLGSQSSYASLLSMGALGAILGAFMANKLFKN
                     NQQSLLLSLGLSGLGMLLITAMALLKLPVIVIALGNLWFECFLTIFNIHFFSIVQKKV
                     PEALLGRVFSSIVTTAILLMPLATTIMTCIPASVHLATFAVIGIGIMATASLAYYCNY
                     RQSSKKKPFI"
     gene            complement(55017..55910)
                     /locus_tag="TV191_000053"
     CDS             complement(55017..55910)
                     /locus_tag="TV191_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1506611.1"
                     /translation="MTNHQLGKAFRSIRQNRNITLQQLASKDVSLSQLSRFERGESDL
                     SVTKFLTALDSMQVEISEFMDIAANFKQTEQIQFMSQLIKLEYARDIEGFKQLQKQEL
                     AKHQADPDTNRYYLNSILLQGFICKCNPSIPFPKAYLDEVTDYLFRTESWHIYELILI
                     GNLYLFIDIPLLDKMGKEILNNHTYYESISTNKHLVTITLLNIWETCIHRHQLDYARY
                     YQKQILALLNNETKLYEKTIFLFLKGLEDYQRGQCLSGIKDMTTAISIFESLDCPHLA
                     HNYQKDFERFVASSSLICKKT"
     gene            56279..56452
                     /locus_tag="TV191_000054"
     CDS             56279..56452
                     /locus_tag="TV191_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1506612.1"
                     /translation="MPIIVILGLAIFSVVKVIIFLCFYKAFEKKQLKKLEQDQKETKQ
                     AIDQEESKKAFPF"
     gene            complement(56497..57432)
                     /locus_tag="TV191_000055"
     CDS             complement(56497..57432)
                     /locus_tag="TV191_000055"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEL1506613.1"
                     /translation="MVSTATKIATFAFNNCLMNAAGVYCMTKEELLAIEASEAGSFVT
                     KTGTLAPRQGNPEPRYADTALGSINSMGLPNHGYQYYLDIVTEMQKDQASKHHFLSVV
                     GMSAEETETILKAIQASDYQGLVELNLSCPNVPGKPQLAYDFEATDQLLKKIFSYYTK
                     PLGIKLPPYFDIVHFDQAAAIFNQYPLAFANCVNSIGNGLVIDDEQVVIKPKNGFGGI
                     GGDYIKPTALANVHAFYQRLNSSIQIIGTGGVKTGRDAFEHILCGAAMVQIGTALHQE
                     GPAIFKRITKELQDIMAEKGYQTLDDFRGQLQYKP"
     gene            57675..58370
                     /locus_tag="TV191_000056"
     CDS             57675..58370
                     /locus_tag="TV191_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003084158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEL1506614.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIAFDLAFTSVLKRAIKTTNLALEYSDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPDMAKDDEHSAHTDRRYAHLDHSVIPDAENLKVTLERAL
                     PFWEDKIAPALVDGKNVFVGAHGNSIRALVKHIKQLSDDEIMNVEIPNFPPLVFEFDD
                     KLNLTAEYYLGGE"
     gene            58479..59000
                     /locus_tag="TV191_000057"
     CDS             58479..59000
                     /locus_tag="TV191_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEL1506615.1"
                     /translation="MKVKERREAITDRLSQAQEAISATSLAKALGVSRQVIVGDIALL
                     RAQQLDIISTPKGYILSNALFSHHYSARIVCQHGPEQTRQELELILAHDGIVTNVEVE
                     HPIYGMLTAPLNIKSSADINNFIEKLGASKAELLSSLTEGLHTHLLSCPDQEAFEEIK
                     RDLAAAGILYGEQ"
     gene            59395..59934
                     /locus_tag="TV191_000058"
     CDS             59395..59934
                     /locus_tag="TV191_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1506616.1"
                     /translation="MTKKPTQLIAYSSILVAFAILIPMIMPIKLIIGPASFTLASHLP
                     LFLAIFISIPVAILVGIGTGLGFLLAGFPMIIVMRAFSHVLFAAIAAFMLKRQPKWLE
                     TPLRTFVFGIIANVIHGLAEFLVVYLMTATAATDLSYFWSMLMLVGFGSLLHGMVDFY
                     LALFIWRFLRQKGHLSVTS"
     gene            60073..60843
                     /locus_tag="TV191_000059"
     CDS             60073..60843
                     /locus_tag="TV191_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEL1506617.1"
                     /translation="MKTPEQILAATITIGEHKVAKPFLAKAILGFIGGAMISLGYLLY
                     VRIAASGLETFGAFSSILGACAFPIGLIIILMAGGELITGNMMAVSAAFFAKKIKAKD
                     LMANWLVITLFNILGALFVAFVFGHFLGLTATGSFKEEVIEVAHAKLAATPLQAIVSG
                     IGCNWFVGLALWLCYGASDATGKLLGTWFPVMTFVALGFQHSVANAFVIPAAIFEGGA
                     SWIDFATNFALVYVGNVLGGAIFVSLFYYKAYDHSKEA"
     gene            60955..63009
                     /locus_tag="TV191_000060"
     CDS             60955..63009
                     /locus_tag="TV191_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HEL1506618.1"
                     /translation="MASWIKKKKASIPRRIHLLFLVIVFLFVALILRLAQMQIYEKDF
                     YKAKLTASTVYKVKSSMPRGTIFDRNGKVLVSNRIKDVVTYTRSPKASAKDIKALAHQ
                     LAAYISYPEAKVTVRAKKDYYLADPEAYAKTVQALPQKDKVDRFGNKLVEAQIYQNAA
                     ASLKETDLTYSDQELKVIAIFNQMNAAAVFSTVKLKTSALSEQDIAIIMANKSKLPGI
                     SVGTDWERQVEETSLAAIIGRVSSEEAGLPKEEAKAYLKKGYSLNDRVGTSYLEKQYE
                     EVLQGKHEIREIKTSRSGEVISDKIVEKGQMGRNLKLSVPLDFQQGVEQILNQHFQTE
                     LKNGQAAYSEGIYAVALNPNTGAILAMAGLSHNPKTGELQKDALGTITDVFTPGSVVK
                     GATLAAGWQAGVIQGNQVLIDQPIQFGGSQPINSWFTSGQHPITASQALEYSSNTYMV
                     QVALRMMGQDYVTGMTLANTGMKETMKKLRAAYAEFGMGVATGVDLPGESSGYLIDQY
                     NTANVLTEAFGQFDNYTTMQLAQYVSTIANGGSRLAPHIVEGIYQDNDQSGPGKLSKA
                     IETTLLNKVHLAADSLAIIQDGFYQVVNSGSGYATGRALAGGPVTISAKTGTAETYAK
                     DKNGQALSTFNLNVVAYGPSASPQIAVAVMYPHATDSLAKAHQYVAKDIINLYMKMYK
                     NQ"
     gene            63021..63617
                     /gene="recR"
                     /locus_tag="TV191_000061"
     CDS             63021..63617
                     /gene="recR"
                     /locus_tag="TV191_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEL1506619.1"
                     /translation="MLYPIPIAKLIESYSKLPGIGVKTATRLAFYTIGMSDEDVNDFA
                     KNLLAAKRELTYCSICGNLTDDDPCHICTDSSRDKEIILVVEDSKDVSAMEKIQEYHG
                     YYHVLHGLISPMNGVGPDDINLKSLITRLMAGEATEVIVATNATADGEATAMYISRLL
                     KPAGIKVTRLARGLAVGSDIEYADEVTLLRAIENRTEL"
     gene            63765..64811
                     /locus_tag="TV191_000062"
     CDS             63765..64811
                     /locus_tag="TV191_000062"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEL1506620.1"
                     /translation="MSKQTLILLYGGRSAEREVSVLSAESVMRAVDYTKFFVKTYFIS
                     QTGQFIKTQEFSSRPTLTERLMTNDTIRLEQQIRPSDIYEEGAVVFPVLHGPMGEDGS
                     IQGFLEVLKMPYVGTNILSSSVAMDKITTKRVLESAGIPQVAYTVYIEGQDLDRCLAE
                     TEAVLSYPVFVKPANMGSSVGISKAESEEELRAAILLALTYDSRILIEQGVLAREIEV
                     GLLGNTDVKSTLPGEVVKNVDFYDYQAKYIDNEITMAIPAAIDESAMTSMRTYAETAF
                     KAIGACGLSRCDFFLGQDGQIYLNELNTMPGFTQWSMYPLLWEHMGLSYAELIEELVR
                     LAQEMFEKREGHLI"
BASE COUNT        18167 a        12229 c        15743 g        18856 t
ORIGIN      
        1 tgtaaaaaac aaacaagaaa acgtatacaa aaacataaac attcattttc aggcgaaaaa
       61 gtgtaatcgt ttacacagat tggctgtgag aaatacccta tttttgaatg ctgcttggag
      121 taaactaggg gtgtaagcaa aagctaagag tcttagcagt gaattcacaa aacattagaa
      181 agaggtaatt cttatgactg ctcaaacacc gattcatgtt tactctgaaa ttggcaagct
      241 gaaaaaggtt ttgctccata ggcctggcaa ggaaattgaa aacctgatgc cagactactt
      301 ggaacgtcta ttatttgacg atattccatt tttggaggac gctcaaaaag agcatgatgc
      361 ttttgcacaa gcattacgag atgaaggcgt agaggtgcta taccttgaaa cactagctgc
      421 tgaatcactt gtaacaccag aaattcgtga agccttcatt gatgaatacc taagcgaagc
      481 taatattcgt ggaagggcaa ctaaaaaagc tattcgtgag ctactgatgt ctattgaaga
      541 caatcaggaa ttgattgaaa aaacaatggc aggtgtgcaa aaatcagaat tgcctgagat
      601 tccagcagca gaaaaaggct tgactgactt ggttgaatca agctatcctt ttgcgattga
      661 cccaatgcca aacctttatt tcacacgtga tccgtttgca actattggta caggtgtttc
      721 gcttaaccac atgttctcag aaacacgcaa tcgtgaaaca atctatggta agtacatttt
      781 cacacatcac ccaatctacg gtggcggcaa ggtacctatg gtttatgacc gtaacgaaac
      841 cactcgtatc gagggtggag atgagctggt tctttcaaaa gatgtgcttg cagtaggtat
      901 ctcacagcgg acagacgcag catcaattga aaagctcttg gttaacatct ttaaacaaaa
      961 tcttggcttc aagaaggttt tggcctttga atttgctaac aatcgtaaat tcatgcacct
     1021 agataccgtc tttacaatgg tggattatga taagttcacg attcacccag aaatcgaagg
     1081 agatcttcgc gtttactcag tgacctatga aaatgaagag cttcgtattg tagaagaaac
     1141 tggtgatttg gctgagcttt tagctgctaa tctgggagtt gagcgtgttg agcttattcg
     1201 ctgtggtggt gataaccttg tggcagctgg tcgtgagcaa tggaacgacg gctcaaacac
     1261 gctaacaatc gcaccaggtg tcgtggttgt ttataaccgt aacactatta cgaatgccat
     1321 tcttgaatca aagggcttga agctcattaa gattcatgga agtgaattgg ttcgcggtcg
     1381 tggtggacct cgttgcatgt caatgccgtt tgaacgtgaa gacatctagg agaggcaaat
     1441 gacaagggtt attgttggaa atcagccttt tcaacgggca gctagcttat atattcgcta
     1501 tcaggttttt gtcttagaac ggcagattga tcggcaagat gaatttgatt gcttcgacga
     1561 taacgatcgc gtgtatgcag tcttgtatga tggtgatcag cctgtatcca cagctcgctt
     1621 tttacccaca gctaaagatc aggctcgtct aacaagagtt gctacgctgc gtcagtatcg
     1681 tggtaggggc tatggtgcgc aggtgataga agcgcttgag cagtatgcca gagagcaagc
     1741 ttacgagcga ttggttattc atagcgagat tagcgcacag tcattttatg aaggtcttgg
     1801 ctatcaagcc tttggcgagc cttatgatga agacggtgag ccttgtcaat cagtagaaaa
     1861 atatttataa aaaggagaat ttaaatgaca caagtatttc aaggacgtag cttcttagca
     1921 gaaaaagact ttacacgtga ggaatttgaa tacctcattg attttgcagc acacttgaaa
     1981 gaccttaaaa agcgtggtat tccacatcac tatttagaag gtaaaaatat tgccctcttg
     2041 tttgaaaaaa catcaacgcg cacacgtgct gcctttacaa ctgcggcgat tgatttagga
     2101 gctcatcctg aataccttgg cgctaacgat attcagcttg gtaaaaagga atcaacagag
     2161 gacacagcta aggtattggg tcgtatgttt gatgggattg aattccgtgg ctttagccaa
     2221 cgtatggttg aagaattggc agaattctca ggtgttccag tgtggaatgg cttgactgat
     2281 gaatggcacc caacccaaat gcttgcggac taccttactg tcaaggaaaa ctttggtaag
     2341 cttgaaggct tgaccttggt ttactgtggt gatggacgca acaacgttgc taattcactg
     2401 ttagtagcag gtaccttact aggtgtgaat gttcatatct tctcaccaaa agagctcttc
     2461 ccagcagaag acatcgtgaa gctggctgag ggctatgcta aagcatcagg tgcgcatgtg
     2521 ttagttactg acaatgctga tgaggctgta aagggcgcag atgtgcttta cactgatgtg
     2581 tgggtgtcaa tgggtgaaga agacaagttt gaagagcgtg tgaagctctt gaagccatat
     2641 caagtgaaca tggagcttgt taaaaaagcc gccaacgaca accttatctt cttacattgc
     2701 ttgccagcct tccatgacac aaatactgtt tacggaaaag acgttgctga gaaatttggt
     2761 gtagaagaaa tggaagtaac agatgaggtc ttccgcagca aatacgctcg tcactttgac
     2821 caagcagaaa accgtatgca cactattaaa gcggttatgg ccgcaactct tggtaatctt
     2881 ttcattccaa aagtgtaagc tgtgattggt accttttaat ttattttagc tcatttcatt
     2941 aatttaacat ttaactacta aaaaacgtac tttaactaca tgacgagtcg ttctggttct
     3001 cgtgtccttg accggaactg ggacggctta tttttatgaa aaggtaagag gtaatcacta
     3061 tgacagaaga aaaaaaacga ggttttaaaa ttccttcttc ttacactgtt ttgtttatca
     3121 tcattgctat tatggcagta ttaacctggt ttattccagc tggtgcttat gagactgcta
     3181 aggatggcgg tgtgatttca gggacctacc aaacggttaa gtcaaaccct cagggctttt
     3241 ttgacatttt aatggcacct gttcgaggca tgctaggtgt caaagggact gaaggggcaa
     3301 ttcaggtttc tttctttatt ttgatggttg gtggcttttt aagggttgtc aacaagacag
     3361 gtgcgcttga tacagggatt gcttctgttg tgcgtaaaaa taagggtaga gaaaagctgc
     3421 ttattgcgat tttgattcct ttgtttgcac ttggtggcac aacctacgga atgggagaag
     3481 aaacaatggc gttttaccct cttcttattc cggtaatgat tgcggttggc tttgatagca
     3541 ttgttgcagt agctattatc ctgattggtt cacagattgg ctgtttggcc tcaaccatca
     3601 atccctttgc tactggagtg gcagcagatg cagccggtgt tagtatcgca gatggtatga
     3661 tttggcggat tatccaatgg gttgtccttg ttggtatgtc tatctggttt gtttacagtt
     3721 acgctagcaa gattgaaaaa gacccaagca agtccttggt tgctgacaaa gctgaagaac
     3781 ataaggaatt cttccagctg caaaattccg gtgaggattt gactagtcgt caacgaaagg
     3841 ttttagccat ttttaccttg acatttgtca tcatgattct tagcttgatt ccttgggaag
     3901 attttgacat tcaattattt acaaatatca acacttggct aacaacaaca cctgttttag
     3961 gtggtattat tggtaaaaca atgggagcct ttggtacttg gtatttccca gaaattacca
     4021 tgctctttat catgatgggt gttttagtgg ctgttgttta tcgcatgagt gaagatgact
     4081 tcttctcagc ctttctaagt ggtgcaggtg agttcctcgg tgttgcgatt atttgtgcgg
     4141 tagcgcgtgg tatccaagtg atcatgaatg gtggtatgat tacagcaacc attcttcatt
     4201 ggggtgaaac aggtcttgca ggcttgtcat cacaggtctt tgttgtcttg gcctatattt
     4261 tctatttgcc aatgtccttc ttgattccat caacatcagg acttgccggt gcaacaatgg
     4321 gaatcatggc tccgcttgga caattctcaa atgttcctgc tcatttggtt atcacagcct
     4381 tccaatcagc atcaggtatc ttaaacatga tttcaccaac ctctgctatt gttatgggag
     4441 cgctcgcact tggacgtatt gatctaggta cttggtggaa atttatcggc aagtttatcg
     4501 ttatggtaat gcttgttagt gttttgttgt tagtagtagc gacattcttt taagagatag
     4561 gaggctccta tggaaaccta tatccaacca agacaccaag aggcttgtgt agccgcgatt
     4621 aaaaaaatag tatcttaccc ttctgtgcta aatgaggggg aaaatgacac accctttggc
     4681 caagccattc aagatgttct tgaagcaacc ttagccctgt gccaagatct tggttttaat
     4741 acctatattg atcctaaagg ctattatggc tatgctgaat tgggcgatca aacagaggtg
     4801 cttgctatcc tttgtcactt agatgtggtg cctgctggtg atttgaagct gtggcataaa
     4861 gatcccttta cttgtattga aaaagatggc tgcttgtatg gacgtggcac tcaagatgac
     4921 aaggggccat cgatgatggc actctttgcc actaaagcac ttatggacgc tggtgtggtc
     4981 tttaacaaac gcattcgctt tatctttgga acagacgaag aaaccctctg gcgctgtatg
     5041 aaccgttata atgaagtaga ggaggaggca acctttggtt ttgccccaga ctcaagcttc
     5101 ccattgacct atgctgaaaa ggggctttta caagctaagc tagttggtaa gggatcgcct
     5161 aaactcaatc ttgaggtggg tcaggcctat aatgtcgttc cagctagagc ctcttatcag
     5221 ggagacaagt tggaggcatt aaaggaagag cttgacaggc ttggctttga atatgttgtc
     5281 aaagatgacg agctaaccgt ctatggactt gctcagcatg ccaaggacgc tccagatggg
     5341 attaatgccc ttatcaggct tgcaaaggct cttgtagtgc ttgagccaga gccagtcctt
     5401 gactttcttg ctcatgtggt tgatgaagac ggcagagcag tcaatatttt tggtccagtt
     5461 caggacgagc catcaggagg gcttagcttc aacgtagctg gtcttacctt aacaaaagag
     5521 atgacagaga ttcgtttgga cattcggatt ccggtcttag cagataaaga taccttagta
     5581 gaccagttaa gccaaaaagc gcaggactac ggtctagctt acgaggaatt tgattatttg
     5641 gcacccttat atgtgccctt ggacagcgag ctagtaacta ccctgttaga ggtatatcgt
     5701 aaaaaaacag gggaccaatc gccagcccaa tcatcaggtg gagcaacctt tgctcgtaca
     5761 atggctaatt gtgtggcctt tggagcatta tttcctgatg ctgttcaaac agaacaccaa
     5821 gaaaatgaac atatcgtctt agcagatgcc tatcgtgcaa tggatattta cgcggaagcc
     5881 atctaccgac taacacgata agatgaggag tatcatatat gacaaaacaa aaaattgttg
     5941 tcgcacttgg aggaaatgca atcctctcaa cagacgcgtc agctaaggca caacaagagg
     6001 ccttggtttc gacatcaaaa tcactagtga agttaatcaa agaaggccat gaggtgatta
     6061 tcacgcatgg caatggtccg caggttggta atctcttatt gcagcaggca gcagctgatt
     6121 ctgagaaaaa tccagccatg ccattagata cctgcgttgc catgacagaa ggcagcattg
     6181 gcttttggtt agtcaacgcc ctagacaatg agctgcaagc ccaaggcatc acaaaggaag
     6241 tggcagcagt tgtcacccag gtcattgttg atgaaaatga ccctgccttt aaaaatccga
     6301 ctaaaccaat tggtcctttc ttaaccgaag aagacgctaa aaagcaaatg gcagaatcag
     6361 gtgctagctt taaggaggac gctggtcgtg gctggcgtaa ggtggtgcca tcaccaaagc
     6421 caattggtat caaagaagct aatgtgatta gaagcttagt tgattctggt gttgtggtgg
     6481 tcagtgctgg tggtggcggt gtgccagttg ttaaagaccc tgcaagtaaa acgcttaccg
     6541 gtgtggaagc tgttattgat aaagactttg ctagccaaac cctttcagaa ttggttgacg
     6601 ctgatctctt tattgtcttg acaggtgttg ataatgtcta tgttaacttt aacaagcctg
     6661 atcaaagaaa attggaagag gtaacggttt ctcaaatgaa ggaatacatc gctcaggacc
     6721 aatttgctcc cggaagcatg ctgcctaagg tggaggctgc aattgctttt gtggaaaaca
     6781 aatcaaatgc caaagctatc atcacatcgt tagaaaatat tgacaatgtt ctctcagcaa
     6841 atgctggtac acaaattatc gcaggctaat tcagatgact gcacaatgag cttaggcttt
     6901 tgtgctttga taggttttag ctgataagct tgaaaaattg atttaaaagg ttaaattagg
     6961 ttaatttagc cttttctttt acttttaatc ggtgtataat aagcgtaata tttttttatt
     7021 tttactcatg attagaatgg taaaaaataa aggtgactta gtcgcgaaaa tgatttaaag
     7081 gaggagctat gaaaaaaagc tttattcatc aacaagagga aatttccttt gttaaaaata
     7141 catttacgca gtatttgatt gctaagcttg atgttgttga ggtgcaaggt cctattttaa
     7201 gtagggtcgg agacggcatg caggacaatt tatctggggt tgaaaatccg gtatctgtcc
     7261 atgtcttgaa cattcctaat gcaacctttg aggtggtgca ttcgctagca aaatggaagc
     7321 gtcatacctt agcacgtttt ggctttaatg aaggtgaagg tcttgtggtg aatatgaaag
     7381 cgctccgtcc tgatgaagat tcgctagacc agacgcattc agtgtatgtg gaccagtggg
     7441 attgggagaa ggttatccct gatggtcagc gcaatctagc ttacctcaaa gaaactgtcg
     7501 aaacgattta caaggttatc cgcttgacag agctagctgt tgaggcacgc tatgatattg
     7561 aagctgtctt gccaaagaaa attaccttca ttcacaccga ggagcttgtt gccagatacc
     7621 ctgatttgac accaaaggag cgtgaaaatg ctatcacaaa agaatttgat gcggtatttt
     7681 tgattggtat tggcggtgta ttgccagatg gcaagccaca tgacggtcgt gcgccagact
     7741 atgatgactg gaccagtgag tcagaaaatg gctaccatgg cttaaatggt gatattctcg
     7801 tttggaatga gcagctaggc acagcctttg agctattctc aatgggaatt cgtgttgatg
     7861 aagaggctct aaagcgtcag gtggacatta ctggagatca ggaacgccta caatttgatt
     7921 ggcacaaatc gctgctaaat ggtctgttcc ccctaaccat cggtggagga attggtcaat
     7981 cgcgtatggc catgtttttg cttcgtaaaa agcacattgg agaggtccaa acatcggtgt
     8041 ggccacaaga ggttcgcgat acctacgaca atattttata gatgatacgg aggctaggtt
     8101 tttacctata gcctctattt ttgtccctaa gtgatgcttc attagagctc atttagtgct
     8161 aagcaggctc gtcagttata taataggtca aaaatttgaa aaaatgaatc atttttaagg
     8221 cttgacacta gatttttgtt ataatatcag ttatgagaat tgtatcaggt gaatttggag
     8281 ggcgtcccct aaaaacgctc gaaggcaaga ctactcgacc cacatcagat aaggtacgtg
     8341 gcgcgatttt taatatgatt ggtccttatt ttaagggcgg acgtgtctta gacttgtttg
     8401 ctggatcagg tggcctatca atagaggcta tttctagggg catgtcagag gcagtgctgg
     8461 ttgagcgtga tcgtaaggcg caagccatta tccaagccaa tattaagatg acaaaagcta
     8521 gccagcaatt tacgctatta aaaatgaacg ctgagcgtgc acttgatcac ttatccggtc
     8581 agtttgatgt ggtgtttttg gacccacctt atgctaagga aacgatagta gccaatatag
     8641 aggccttggt ggagaaaaat cttttaagcg acgatgtgat gattgtttgt gagacggatc
     8701 ggtcggtagc tctgccagag gcaattgcct ggctagggat ctggaaagaa aaacaatatg
     8761 gaattagcaa ggtaacagta tatgtcaggt aagattggac tttatacagg gtcatttgac
     8821 ccagtgacaa atggacacat ggatatgatt aagcgtgcta gccatttgtt tgagcatgtt
     8881 tatgtcggga tttttaacaa tccaaataag cagagctttt ttacttttga gctgcgagct
     8941 caaatgctaa gcgaagcggt ttgtgccttg ccaaatgtga cagtggtttc tgccgagcat
     9001 ggtcttgcag ttgacctggc tagggagctg tctgtgaccc accttatccg agggcttcgc
     9061 aatacagctg attttgacta tgagataggc ttagagtatt ttaatcatag actagcccct
     9121 gatattgaga ccatttacct gatggcgact catgacctgc agcccgttag ctccagtcgt
     9181 atcagagagt tgattgcatt tagagcgcca attactggtt tggttccgca ggctgttatt
     9241 aatcaagtgg agaaaatgaa tgaaaacaat aaaaaaaatt aaatggtggc tgattggctt
     9301 tgttgccttg ctttttctac tgttgacact gtttttcccc ttgccttatt atattgaaat
     9361 gccaggtgga gcctatgata ttcgctcggt attgactgtc aatggcaaag aggataagga
     9421 aaagggagct tatcagtttg ttgtagtgag cctcagtcgg gccaccttgg ctaaattgct
     9481 ctatgcttgg ctaacgcctt tcactgagat tagcaccatg gaagatacta ctggtggcta
     9541 tagcgatgct gactacctgc gaattaatcg cttttatatg gaaacctctc aaaacagcgc
     9601 tgtttatcag gcccttactc tagcaggcaa ggaggtaagc tttgattata agggtgttta
     9661 tgtcttagac gtcagcaagg attctagctt taaaggtgtg ctgcacctag cagatacagt
     9721 gacaggtgtc aatggtaaaa catttacaac gtctgccgat ctgattgatt atgtttctca
     9781 tttgaccttg ggagatgagg tgcaggtaca atttacaacc gctggtgagt caaagactga
     9841 aaaaggaaag attattaagc ttaaaaacgg taaaaatggg attggcatta ccctgacaga
     9901 ccacacacag gtcatttctg gtgatgaggt cgactttagc actggaggtg tgggtggacc
     9961 aagtgcaggc ttgatgttta ctcttgatat ttatgatcaa atcaatcacg aagacttgcg
    10021 caagggacgt gtgattgctg gtacaggaac cattggcaag gatggaaaag ttggagatat
    10081 tggcggggcg ggcctaaagg tggctgccgc cgccgctgct ggtgctgata ttttctttgt
    10141 tccaaataat cctgtgcata aggacgtcaa aaaagcaaat cctaaggcta ttagcaatta
    10201 cgaggaggct aaaaaagcag ctaaacgact aaagacagca atgaaaatta ttcctgtgaa
    10261 aaccgttcaa gatgctataa gctaccttaa aaaatagaag caatgcgaag caggctaata
    10321 gggcatgctc tgtcttgctt ctagttggtg gaatttagct agctcaaagg tcttgagacc
    10381 taagcataag gtctagacag tattctagag ctagacctta tgcttgatcc tgaacaagga
    10441 agaccgccaa agaagaacaa aatcctcagg ccaaaagagc ccgtagggaa atattgccat
    10501 tatctatcaa ggctttttga agaaaatcac ttaaagacag tagggcgtta ggctttactg
    10561 tcttagtttt tcttgcctga agtcatggct gctgatgatg ttacatcaag gcttactagc
    10621 cagcagagca caaggagcag ctttggctta ggtttatttt ctctgctgac tagtaaagaa
    10681 ggttgctgtc agtctgctta caaaaaccta aaaatagtgt ataataggta ggctatgggc
    10741 tgtcaggagt cgctagcctg cttacccaga ccagcccttt gagaagagca agcatggctc
    10801 ttctcagaat aacccaggat taacagacat caaaattaat gctaaggaaa ggagctatat
    10861 gaaaagagat attttaccag agatgtataa ttacaataaa tttcccggtc cggaatttat
    10921 tcattttgat cattatgtca aggctgaagg cattgagtta ttgctgctga aaaatgaaaa
    10981 aaatgctttt aacacaacga gctttggtca gcgcttcaca gagatattat taaagtatga
    11041 ctatattgtt ggagattggg gcaatgaaca gctgcgtctc aagggctttt acaaggatca
    11101 tcatgatgtc aaaaaagcta gtcgtatttc tcgcctagaa gactatatta aagaattttg
    11161 taactttggc tgtgcctatt ttgttttgga aaaccctaat cccaaggaca tgccaaaaga
    11221 ggaggaaagg ccatcaaggc gcaggaaatc gtctaaagcc aatcgccgca gaaatcagcc
    11281 tcagcatagt cagcaggcac ctgctaaaga caacttcaaa aagctaacca aggataggtc
    11341 agcggacaag ccaagcttta ccagcaaaaa gcgcccagct cctaataaga ccaagggaaa
    11401 ccaaaggcgc tctcgtacta gtcaactgaa ccataaaacg gatcacttta tcatcagaaa
    11461 gaaggacaat taatctatga aaccatcaat ctatggccta acgcgcgacg agctaattgc
    11521 ttgggcgatt gacaatggtc aaaaggcatt cagagcgaca cagatttggg actggcttta
    11581 cagaaaacgg gttcaatcct ttgatgaaat gactaacatt tctaaggaat ttgttgccat
    11641 tctaaaggac agcttttgta ttaatccctt gaagcagcgt gttgctcagg aatcagctga
    11701 tggaacggtt aagtatttgt ttgaattgcc agatggtatg ctgattgaaa cggttttgat
    11761 gcgtcagcac tatgggcagt cggtctgtgt aactacgcag gttggctgta atataggctg
    11821 caccttctgc gctagtggct tgattaaaaa gcaacgggat ttaaacagtg gtgaaatcac
    11881 tgcacaaatt atgatggtgc aaaactattt tgataagcgt gctcaagacg aacgtgtcag
    11941 ccatgttgtt gtgatgggga ttggagagcc ctttgataat tatcaaaatg tgatgacctt
    12001 tcttcggacg atcaatgatg atcatgggct tgctattggt gctcgtcaca ttactgtttc
    12061 aacctcaggc ttggctcaca agattcgtga atttgccaat gaaggagtcc aagttaatct
    12121 ggctgtgtca ctgcatgcac ctaataatga gctgcgctca agtatcatga ggatcaatcg
    12181 ttccttccca cttgataagc tcttttcagc aatcgaatat tacattgaaa caactaatcg
    12241 tcgtgtgacc tttgagtata tcatgcttaa taaggttaat gatggggtag agcaggcaca
    12301 ggaattggca gatttgacca aaaggattcg caagctgtct tatgttaacc tgattcccta
    12361 taatcctgtc tcagagcatg accaatacag tagaagtcct aaggagcgtg tggcagcctt
    12421 ttatgacatt ctaaagaaaa atggagtgaa ctgtgtcgtt cgtcaggagc atggtacaga
    12481 tattgatgct gcctgcggtc agctgcgctc taataccatg aaaaaggacc gacaaaaagc
    12541 agcagctgca aggacatgat gacttggtca aggttgctga tttgattgat aggagatgga
    12601 gataaaaatc tgacctcaaa taaagcaaac aaataggtct agttttctga gatcccgaaa
    12661 gcaggtcttg ttcgtttttt aatgaatgag actaggtcat aaagtacatg cgttaagaat
    12721 gtctaaagtg cagctctttt tgtcccagcc tccctctttt atcttggtag cagttgtcaa
    12781 gtaattgcta agcaacagtg ttttatcttt attggctgta aaaaaagata tagtgccttt
    12841 attcacacct tttctgaatc acttgagcct tgttctgacc gctccttttg gtgcttctga
    12901 tccatatagc ctaagctttt cagagctatg aatcgaggca aaataatagg tgttagccct
    12961 agctgcttga tgtagctagg gcttttgtga cctagctgcc agtgagcctt tcaaatagca
    13021 atatggctat aaggcccagt gtcagatagg gaataaaagg gattttctta gtttgtagaa
    13081 gtaggcaggc tagaattccg atcagactgg caatttggac gatccataac aaagagctaa
    13141 gcttgaccac aagagcaaga ttagctaggt aaagaaaatc tccggcacca atattgatag
    13201 gaaaagctac gcttagcagt gcaagcaaaa gcaatagcac tgttaacagg ttaatgctat
    13261 aaaatggcag cagaaacaaa aagctcatca gccagatgag caaaggatac tcttgactgt
    13321 ctaaatcaaa aaagcacagt agcaaagaga agcataggag ataaagctgt gtccaggtca
    13381 agccgcaaag ggcagccagt ccgaaaatga ggctggtgat tatttctaaa taaggaagca
    13441 taacccagtg cttttgttca tgcttagagt tgtaagtggg ctttgccata ggaaaaaaga
    13501 ggcttgaaag atgaagttga cctatataga gcttgaccca agcctttgct tgctgttcag
    13561 aaaacaggtt aagtattagc cgaaagaggt ttcccacaag aaaaccacaa tagcaataaa
    13621 aaatagtgtt catacttatt tatccgaaaa acaatttaaa ttcttgcaat attttaaaaa
    13681 acggtgtaca atgaaactat aaaacgagaa tgattctaaa taagctgttg atacttatct
    13741 gaattggctc gttatcgtcg aatggagctg acaagagagt gacttttctt gctgcatacc
    13801 attcatgccc ttttatatct atcagtaagg agagtttatt atgacaaaca cactcgttga
    13861 aaacatttat gcatcagtaa ctcataatat ttctaaaaaa gaagcatcaa aaaatgaaaa
    13921 aaccaaggct gttttaaatc aagcagtagc agatctatct gtagcagctt caattgttca
    13981 tcaggttcat tggtacatgc gtggtcctgg ctttttatac ctgcacccta agatggatga
    14041 gctattagac cgcttgaacg cgaacctaga tgagatgagt gagcgcttga ttactattgg
    14101 tggggcaccc tactcaaccc tagaggagtt ttcacagcat tctaagctag atgaaacaaa
    14161 gggaagctat gataagtcag tagctcagca tttagctcgt ttggtagagg tttaccttta
    14221 ccttaccagt ctttatcagg ttggtttaga cattactgat gaagagggtg atgctgcttc
    14281 aaatgatttg ttcacagcag caaaggctga cgctgaaaag actatttgga tgctacaggc
    14341 agagcgtggt caaggtcctg ctattttcta aagcgtcata caactgatat aacataaaaa
    14401 aggcagagcg tggtatagcc ctgtcttttt aacgccttta aagtcagcta ttagtgctag
    14461 tgatgtcagg tctcacagct tttttatgat ggatgaccaa catttttaga ccttgtcacc
    14521 acagcagagc atgtggcatt tagtccacct tgggctcacg tcgatggtct tacttatgat
    14581 atatcaaggc ttgtgacatt accgttgcct tttatcttca gtctgagctg ctggttccta
    14641 ctgctgatgc tgcttgatag tgttatagtg attttcagaa atatggaaag cgattgcata
    14701 attgtcttga aatctcatgc gtaatttgct aaaatctagt tatatgaaaa cattatacga
    14761 tgtacagcag ctgttaaaag gctttggtat tgttatctac atgggaaagc ggctttatga
    14821 tattgaaatg atgaaaatag agctgcaaag gctatatgat ggtggcttgt tggataaaca
    14881 ggcttattta actgctgagc tgattttacg acgtgagcat cgattagagc taaaaagaga
    14941 agggcaagaa aatgagtcaa aaattgatag ggattgattt gggcggaacc acgattaaat
    15001 ttggtatttt aacctcagag ggtgacgttc aggaaaaatg ggcgattgag acaaatgttt
    15061 tagaggacgg taaacatatc gttccagata ttgtcgcctc actcaagcat cgccttgacc
    15121 tttatggact gactaaggac gattttatcg gtattggtat gggctcacct ggagctgtca
    15181 atcgcacaga tcatactgtt acaggggcct ttaacctcaa ctggagaggc acccaagagg
    15241 tgggatctgt tattgaaagg gagctaggaa ttccctttgc tattgataat gacgcaaatg
    15301 ttgcggccct cggcgagcgc tgggtcggtg caggtgacaa taatcctgat gtggtcttta
    15361 tgaccttagg aacaggtgtt ggtggtggta tcatcgctga tgggaacttg attcatggtg
    15421 tggctggagc tggtggtgag attgggcaca tgatagtaga gccgcttaag ggctttgctt
    15481 gcacctgtgg ctcacagggc tgcctggaga cagtggcctc tgctacaggt gttgttaagg
    15541 ttgctcgtct tttagcagaa gcctacgaag gagattcaag cattaaggca gcgattgata
    15601 atggagaggc tgtctcaagc aaggacattt ttgttgcagc ggaggctggt gatgcctttg
    15661 ccaactctgt tgttgaaaag gtcagttatt atctaggact ggcagcggct aatatctcaa
    15721 atattttgaa ccctgattcg gtcgttattg gcggtggtgt atctgctgcg ggtgagtttt
    15781 tacgttcacg tgttgaaaag tactttatga cctttacctt tccgcaggtt agacagtcca
    15841 ctaaaatcaa aatagcagag cttggtaatg atgctggtat tattggtgca gctagccttg
    15901 caagacaatt tatcacagaa taggagttaa tgatgtcacc acttacaatg attggctggg
    15961 tattgcttgc gggagtgatt gcctattacc tttggaatta tgtttcctat agaagaatgg
    16021 caaagcaggt tgataatgat acctttaagg agctgatgcg tcaggggcaa gtgattgacc
    16081 tgcgcgatcc agcttccttt agggcaaggc atatcctagg cgctagaaat tttcctgccc
    16141 agcagtttac tacctctatt aaggctttga gaaaggacaa gccaatcttg ctttatgaaa
    16201 atgtaagacc tcaatatcgg gtcaaagcag tcaaaacatt acgtaaggct ggctatacgg
    16261 acctttatgt cctaaaagcg ggactagatt attggaatgg taaggttaaa tagccttata
    16321 gtcctttttg ctgagctaac gtttgctgct atgtgtcgga acgttgcaag cagcagctta
    16381 tctaagcttg tcatgctagt ttcacagccc aaagtggctg gccgtataaa cgcagctgct
    16441 tttagatgcc ggtaggagct tttgtcagct tctttaggga ttgttttaag tgatgtagag
    16501 aggccgttct gagagaaagc cttgtagtta gaaaaagaga tgagaaagct aaggctcttg
    16561 ctgctgttgt aagagttagc tttctttttc ttttttgtgt ggcgcattta agggcttgaa
    16621 aacatttaca attccctcag atcggttttt taaaaaaatt tgtgttatac tgttttagtt
    16681 aaaactattt atgctacaag aggaaaaaat gacaaaattt agagaagata ttcgtaacgt
    16741 tgctattatt gcccacgttg accatgggaa aacaacgctc gttgatgaat tactaaagca
    16801 atcccataca ctagatgagc gcaaagagct tcaagaacgt gcgatggatt caaatgacct
    16861 tgaaaaagag cgtggtatta ccattcttgc taaaaatacc gcagtagctt ataacgatgt
    16921 tcgtattaat atcatggata ctcctgggca cgctgacttt ggaggcgagg ttgagcgtat
    16981 catgaaaatg gttgatggtg ttgtccttgt tgttgacgct tacgagggaa ccatgcctca
    17041 aacacgcttt gtgctgaaga aggccttaga acaaaattta accccaatcg ttgtggttaa
    17101 taagattgat aagccatcag ctcgtccagc tgaggttgtt gatgaggttc ttgagctttt
    17161 cattgagctt ggtgcagacg atgatcagct ggagttccct gttgtttacg cttcggcgat
    17221 caatggcaca tcttcgttgt cagatgatcc tgctgatcag gaaaaaacaa tggctccgat
    17281 ttttgatacc attatcgatc atattccagc acctgttgat aactcagctg agccccttca
    17341 attccaggtg tcacttcttg attacaatga ttttgtaggt cgtattggga tcggtcgtgt
    17401 ctttcgtggg actgttaagg ttggagatca ggtgacgctt tcaaagcttg atggcaccac
    17461 taaaaatttc cgcgttacta agctgtttgg cttcttcggg cttgagcgca aggagattca
    17521 agaggccaag gctggtgact tgattgcagt ttctggtatg gaggacattt tcgttggtga
    17581 gacgattaca ccaacggatt gtgtggaggc tttgcctgtt cttcgcattg atgagccgac
    17641 acttcaaatg accttcttgg ttaacaactc tccctttgct ggtcgtgaag gcaaatgggt
    17701 aacctctcgt aaggttgagg agcgtttgct tgtggagctt caaacagatg tgtcccttcg
    17761 tgttgagcca acagaatcac cagataaatg gattgtgtca ggtcgtggtg agctgcatct
    17821 atctatttta attgagacca tgcgtcgtga gggctatgag cttcaggtat cgcgtccaga
    17881 ggttatcatt aaggaaattg atggtgtcaa gtgtgagcct tttgaacgtg tacagattga
    17941 cacaccagag gaatatcaag gtgctattat ccaatccttg tcagaacgta agggggatat
    18001 gcttgatatg cagatggttg gtaatggtca aacgcgtctt atttttctca ttcctgcccg
    18061 cggcttgatt ggttattcga ctgaattttt atcaatgaca cgtggctatg gtatcatgaa
    18121 tcataccttt gatcagtatc tgccagtggt tgctggtgag attggtggac gccatcgtgg
    18181 agcgctggtt tcgattgaaa acggtaaggc aacaacctac tcaatcatgc gtattgaaga
    18241 gcgcggaaca atctttgtta acccaggaac tgaggtttat gagggcatga ttgttggtga
    18301 aaattctcgt gacaatgacc ttggggttaa tatcacaact gctaagcaga tgaccaacgt
    18361 tcgttcagca acaaaggatc agacagctgt tatcaaaaca ccacgtattc taacccttga
    18421 ggaatctctt gaattcttga atgatgacga atacatggag gtaacgccag aatcaatccg
    18481 cttgcgcaag caaattttga acaaagcagc gcgtgataaa gctaataaaa agaaaaaatc
    18541 agcagaataa aggctggttg gtctgagcat cacactccct tgccgcttta actagtaagc
    18601 taggttggca gaggattgaa aggagctttc tgtgttttat cttattattg cagccttgat
    18661 tacctcttat tacctgttta tggcaccaaa gagcgtccgt aacacactag gtatgattgg
    18721 tttggttggt ttggttgccc tattgattgt gctagctggc ttaagtttta tcaaaatcat
    18781 gcaaacgccc aaggaaattt tcgttggtct agccatgata gtattgggct actatgccct
    18841 aagggacatt caaaaaatcc ctaaaaaacc aaagagtaaa cattagcatc aagcattgag
    18901 tcaaatctta atagggtttg actttttctg tctttgtact ggccttatgc gctgctatct
    18961 gtaaaatctt gaaaaagcag ttaaataagg gtaaaatagt agtcaaatag acatagatag
    19021 tgtggataaa aatgaagaca ataacggaat tccaaaataa aaaggtattg attcttggcc
    19081 tggccaaatc gggcgaagca gcagctaggc ttttagcccg gttgggagct attgtgacag
    19141 ttaatgatag caagcccttt gaggaaaatc ccgcagcaca ggctcttctt gaggagggca
    19201 taagggttat ttgtggtagc caccccttgg agctgttaga tgaagacttt tattgtatgg
    19261 ttaaaaaccc agggattcgc tatgacaacc cgatggtggt acgcgcctta gataaggcta
    19321 tttctattct aacagaggtt gagctggctt atttggtatc tgaagcacct atcattggta
    19381 ttacgggctc aaatggtaaa accactacaa ccacaatgat tgctgatgtg ctaaatgctg
    19441 ggaaccattc agctcttttg gctgggaata tcggctttcc tgcttcagag gtggctcaag
    19501 ctgctacagc aaaggatata ctggtcatgg aattgtcttc ctttcagctg ctggggactg
    19561 agcagtttca gccacatatt gcagtcatta ctaacctagt gcctactcat cttgattatc
    19621 atgggagttt tgaggactat atagcggcca agtggcgcat tcaacatcga atgaccgata
    19681 aggattacct tgtgttaaat gctgatcaag agctggtaaa atcattggct caaaagacta
    19741 aagcaagtcc tgtctttttt tctaccaaag aaaaagttga tggtgcttat ttggcagatg
    19801 ggtatcttta tttcaaagag gagaggctga tgtcagcagc tgagcttggt gttcctggaa
    19861 ggcataacat tgaaaatgct cttgccacca ttgctgttgc aaagctaaga ggcatttcta
    19921 atcaagtgat atcaaggact ttgtctcact ttaggggggt gaagcaccgc cttcagttag
    19981 ttggtacatt gaatcaagtg accttctaca atgacagcaa gtcaaccaat atcttggctt
    20041 gtcaaaaagc cttgtcgggc tttgataata gcaaggttat cctgattgct ggtggcttgg
    20101 atcgtggcaa tgaatttgat gagctggtgc cagacctcgt tggtcttaaa aagatgattc
    20161 ttttagggga atccgcagag cgtatgaagc gagctgcaga caaggcagga gtgtcctatc
    20221 ttgatgccaa agatgttgca gctgccacta aaatagcctt tgagcaggca aaggctggtg
    20281 atattatctt gctgagccca gccaatgcta gctgggatat gtatccaagc tttgaaagcc
    20341 gcggcgacga gtttttagca gcctatgacg cgttaaaagg agaggctcaa tgaccaagaa
    20401 aatcattttt accggtggtg gaacagctgg tcatgtcact ttaaacctta tcctcatacc
    20461 gaagtttatc aaagatggct gggaggttca ctatattggt gatgacaaag gcattgagca
    20521 tcaggagatc aaaaagtcag gtcttgatgt cacctttcat gctattgcaa ctggaaaatt
    20581 aaggcgttat ttctcttggc aaaacctgct tgatatcttc aaggtaggct ttggtgtcat
    20641 gcaatcactt tttatcatag ctagactaag gcctaaggct ctcttttcaa agggaggctt
    20701 tgtgtcggtt cctcctgtga ttgctgcaag gcttttaggg gtgccggcct ttattcatga
    20761 gtcggatctt tctatgggct tggctaatag gattgcttat cggtttgcaa caacgatgta
    20821 tacaaccttt gagcaagagc agacactggc aaagctcaag catgttggag cggttaccaa
    20881 ggtgacaggt cctgggagtc gatcggtgac ttctaagcag cttgaagctg ttttggagta
    20941 ttttgatcct aatttaaaaa cacttttgtt tattggaggc tccgcagggg ctagggtgtt
    21001 taaccgcttt atcactgacc atcctgagct aaaggaagac tttaatatca tcaatatctc
    21061 tggcgatcct agcctaaatg agcttagttg gcatctttac cgcgtggatt atgtgactga
    21121 tctgtatcaa ccgctcatgg aaatggctga tctggtagtg actcgcggag gctctaacac
    21181 actttttgaa ttattagcga tgagaaagct ccagcttatt atcccacttg gcaaagaggc
    21241 cagtcgaggt gatcagcttg agaatgctca ttattttaca acaaggggct atgctgagca
    21301 attattggag caggaattga ccctgcctca ttttcaagag aaagtgagag aagtctttgc
    21361 taagcaatcg gactatttat ctgcaatgaa gagctctagc gagctccaat caccagaaag
    21421 cttttaccag cttttaagtg ccgacattag ctccgcgaca aaggaaaatt aaatggcaga
    21481 taagacaaaa cattcagaag aaaaagccgc tttgaccgaa tggcaaaagc gtaatattga
    21541 atttctcaac aagaagcagc agcaggctga gaaagacaaa aaactaaaag aaaaattatt
    21601 aaatgagaaa atagcgcaag ctcagggaga ggcagcttca aaggctgacc aagaagatac
    21661 agatgaagct gaggagaaaa ctgaggtaag ccaagcgggt actgatgagg gtgagccgct
    21721 gccagaagca tcagagcagg aagtcccctc cccaaaagac aagccattaa aagtccccaa
    21781 agaaaaaagt ccaaagcagc aggcacttca aaagggctgg cctgtattgc tggtgtcgtt
    21841 tgtggttttg tgcctgtcga tttttatgat cacaccctat agtaaggtca aggatttctc
    21901 cgtcaagggc aataaaaaaa caagcgttga ggacttagtt agagacagtg ggatcaagtc
    21961 atctgattac tggattactc tattagcctc tccgggttct tatgaaaatg cggttttaaa
    22021 agccaatccc tgggtgaaaa aggtggcttt gcgttacggc tttcccaatc atttccgctt
    22081 tgatgtgaca gagtttgata ttattgccta cgctcaggta gctgaagggt ttcaactgat
    22141 cctagaaaat ggcaagcgag ttgctgctgt caagcaggct gctttgccta aatccttttt
    22201 gattttaaat cttgagcatg aaaaagagat tcaagatgtc attaatcgct tgaccaaaat
    22261 cccaagtgac ctagtcaagg ctatcaaatc agtgtcatcg gccaattcac agacaactaa
    22321 ggatttgctg cttcttgaaa tgcacgatgg caaccttatc agggtacctc ggtcacagct
    22381 tgagctaaag ctgccttatt accaaaaaat caagaagaat cttgatactg ctagcattgt
    22441 tgatatggag gttggtatct atacgaccac tgctgaaatt gaaaacatgc ctgaggtgcc
    22501 agcgtctgct caagcttctc aggcagataa gcctgctgag gcttcaccag agcagggtga
    22561 agagcaggcc acacaggagc agcctagccc tgaaacacct gctaatcctg aggccacaaa
    22621 tccctcagtc gcccagccta ctgagcaggc aaatcaacag taatcgttta gggtaagaga
    22681 agggggcaaa aaagcattta aggctcttaa attaggccct tgttgaacgg caaaaaaaca
    22741 ttaagtttat ataacaaaaa acgtaaaatg gtaacatttt acgttttttt atgatataat
    22801 attccctgaa taattctgct ttttagcagt gtttttgaat agtaaaagtt tggaaagtaa
    22861 gtgaggtcga gtgaatggct agaaatggct tttttactgg tttggacatt ggaacaagct
    22921 cgataaaggt tttggtagca gagtttatct ctggcgagat gaatgttatt ggtgtgagca
    22981 atgttccgag tactggcgta aaagatggca taatcattga tatagaggca gcagccgctg
    23041 ctattaaaac tgcagtagaa caagctgaag aaaaagcagg aatgacaatt gaaagggtca
    23101 atgttgggct gccagcaaac ctccttcaaa ttgagccgac acaaggcatg attcctgttc
    23161 ctagcgaatc aaaagaaatc aaagatgaag acgttgatag cgttgttaag tcagcactaa
    23221 ctaagagcat tactccagag cgagaggtga tttccttagt ccctgaagag tttattgtag
    23281 acggctttca gggcattcga gatcctcgtg gcatgatggg gatcaggctt gaaatgcgcg
    23341 gtctgattta cactggacca agcacaatcc tgcataactt aagaaagaca gttgagcgtg
    23401 ctgggattaa ggttgaaaac atcatcattt ctcctttggc aatggctaag gcggtgttaa
    23461 atgaaggtga acgtgaattt ggtgctacgg tcattgacat gggtggagga caaaccaccg
    23521 ttgcctcaat gcgagcacag gaattgcagt acaccaatat ctatgcagag ggtggcgagt
    23581 atatcacaaa ggatatctct aaggttctta aaacgtcaat gtcaattgca gaggccttga
    23641 agtacaattt tgggcaggct gatatggcag aggcaagctt gactgacact gttaaggttg
    23701 atgttgttgg cagtgatgag ccagttgagg taacagagcg ttacttatca gagattatct
    23761 cggctcgtgt tcgccatatt ctagatcgtg ttaagcagga tttagaaaga ggacgcctgc
    23821 ttgatttacc tggtggcatt gtgctgatag gtggcggcgc cattatgccg ggcgtggttg
    23881 aggttgctca agagattttt ggaaccaatg ttaagcttca tattccaaat caggttggta
    23941 ttcgtaaccc aatgtttgcc aatgtcatta gcttggtcga gtacgttggt atgatgtcag
    24001 aggtggacgt tttagcgcaa aatgctgtat caggcgagga attgctaaga cgtaagccga
    24061 tcgactttac tggccaagaa gcttacttgc cagactacaa tgagactagg ggatttgaac
    24121 cggctcctaa ttatgagcag caagtgcccc aagcagacta cgagcctcaa gaacccgctg
    24181 aaccaaagca aaagatttca gagcgtgttc gtggcatttt tggaagtatg tttgattaaa
    24241 agtaataaag tgaggaaata aaatggcatt ttcatttgat acggcatcca ttcaaggtgc
    24301 aatcattaag gtaatcggtg ttggtggagg tggcggaaac gctattaacc gcatgattga
    24361 tgagggggtt gcaggtgttg agtttatcgc tgcaaacact gatattcagg cattaagctc
    24421 atcaaaagca gaaacagttg ttcagcttgg tcctaaatta actcgtggtc ttggtgctgg
    24481 aggtcagcca gaggttggtc gtaaggcagc agaggaaagc gaagaggttc tcacagaagc
    24541 tttgactggc gctgatatgg tctttatcac tgctggtatg ggtggaggct ctggaacagg
    24601 agcagctcca gtgattgctc gtatcgctaa gagcctagga gccttgactg tggcagttgt
    24661 aacacgtcca tttggctttg aaggcaacaa acgcagtaat tttgccattg aggggattca
    24721 ggagctaaga gagcaggttg ataccttatt gatcatctca aataataacc tgcttgaaat
    24781 tgttgacaaa aagacaccat tgcttgaagc gcttagcgaa gcagacaatg ttttgcgtca
    24841 gggtgtacaa gggattactg atctgattac aagccctggc ttgattaatc ttgactttgc
    24901 cgatgttaag actgtgatgg caaataaagg caatgcactt atggggatcg gtattggttc
    24961 tggtgaggaa cgtattgtag aggcagctcg taaggctatc tactcaccat tacttgaaac
    25021 aacaattgac ggtgctgaag atgttatcgt taacgtgaca ggtggacttg atatgaccct
    25081 cacagaggct gaggaggcat ctgaaattgt tggtcaggca gcaggtcaag gcgttaacat
    25141 ctggctagga acatcgattg atgactctat gagagacgaa attcgcgtaa cagttgttgc
    25201 aacaggtgtt cgtcaggata aggcggagca agcctcagga tttcgtcagc cacgcaccta
    25261 cactcagtct aacgctcagc aggctgctgg agcacaatat gcttcagagc aggtgagaca
    25321 gactgcgcag ccaagctttg atcgtcgttc atcaagcttt gattttgata tgggtgaaac
    25381 acgtgagatg cctaagtctc agcaagctat gccagctcat ggccacaatc ataatcaggg
    25441 ctcagctttt ggaaattggg acttacgtcg agacaatatt gctcgtccag cagaaggtga
    25501 gcttgacaat caattgaaca tgtcaacctt ctcatcaaat gatgacattg atgatgaatt
    25561 agaaacacca ccatttttca aaaatcgtta atgatggatt tacaaaaaaa taaggatatt
    25621 gtttttgaaa atattcgctt agccactcag gcagccaacc ggcctgaaaa cagtgtgtca
    25681 gttatcgctg tcacaaaata tgtggacaag gcagttgcag gtcagctgat tgatatgggg
    25741 attgagcata tcgctgagaa ccgtattgat aagtttctag ataaatatga agccttgaaa
    25801 gataggcaag ttacttggca ttttatcggt actttacagc gtcgaaaggt aaaggaagtg
    25861 attaataagg ttgattattt tcatgcctta gattcagtaa aactggcttt agaaattgaa
    25921 aagagagctg accaccctgt gaagtgtttt ctacaagtta atatttctga agaagaaagc
    25981 aagcatggtt ttaagattgc tgagcttgat gctgctattg aggaaatcag caagatggaa
    26041 aagcttcatc ttgtcggtat catgacaatg gcacctattg atgccagtca gcaagagctt
    26101 agaagcattt tccaaaaagc aaatcaatta agaaaaaact tgcagtcaaa aaagagaaag
    26161 aatatgccgt ttacagaatt gagtatgggc atgagtaacg attatccaat tgctattcaa
    26221 gaaggctcaa cctttgttcg tattggaaca tctttctttc actaaatgga gaataagatg
    26281 gcaattaaag acgcatttaa taagatgatt tcttattttg atactgatgg ggtcagtgaa
    26341 gtagaagagg agctatcctc taaaaagcaa gaagagcctg tgactaaatc acaacagacc
    26401 agcagaccta atcagcagca acaagcagct agagcgagtc agccccagca gcctaagcag
    26461 gctagacctc agatgcaagc tcagcaaaga ccacaatcac aatcaagagc tgcctatgct
    26521 gagcgaccat atcaaggtca aagtcaagca cgtgtttctc atgactacaa tgacagaagg
    26581 gcgacgtcag ccccgtctgc ttctagtcgt cgtgagcaat atcagcatgc tgctcatcaa
    26641 gagcaaacaa ctattgcctt gaagtatcct cgtaagtatg aggacgccca agaaattgtt
    26701 gatcttttga ttgttaatga gtgtgtgctg atcgattttc aatacatgct agatgctcag
    26761 gcaaggcgtt gcctagattt tattgacggt gctagtaagg tattgtatgg tactctgcaa
    26821 agggttggtt cttccatgta tctgttgacc ccatcaaatg tatctgttaa tattgaagag
    26881 atgaatatcc caaataatgg ccaagatatt ggttttgatt ttgatatgaa gagacgctag
    26941 tgtgatgatt tttatactgt tgatacttct aaagctaatt aaggtttatt cctatttgct
    27001 gctagtctat gccttactgt cttggtttcc tggagcctac gactcttggc ttggcaggct
    27061 ggtcagcgat atagtagagc ctatcttaaa accctttaga tcattgaacc tacagtttgc
    27121 gggcttggac tttactattt acctagtgat gattggtcta aatgttttaa gtgagatctt
    27181 gataagagtg ttgatctcat gactgttcaa acaatgcttt atcagcattt tcagcctgat
    27241 gaacacccat ttattgaaag aatgcttgac ttgatcgctc gtgttgaggc taattattta
    27301 ttagaggtta ctgatttttt aaatccgcga gaggtcacga ttttaaaagg cttagtcgca
    27361 gcaaccaatc tgcagtgctt tagctctact gattattatc ctagtgaata tggtcgtgtg
    27421 attgttgctc ctgactatta ttgtctagat aaggcagatt ttgacttggc tttgattgag
    27481 gtgacctata atgctaagtt taatcagctg acacatgcac agattttagg caccttaatt
    27541 aatgaattgg gaatcaaaag agccttactt ggcgatattt ttgttgagat aggtcatgct
    27601 caggtcatga ttaatcgaca gctgttaagc tattgtttag gaacgattgc taaaatagca
    27661 aaagctaggg tcaagctcaa agaaattgat cttgatcagc tgttaaatct gacagctaat
    27721 cagcaggttc tgactgatat aatggtatct agtctacgcg ttgatcgctt gattgctacc
    27781 gtattaaagc aatctagaaa tcaggcgata aggcttgttg aagcaggcaa ggtcaaggtt
    27841 aactatcagc ttgtcactaa agcctctcag cctgtagctg ttggtgattt aatcagcatt
    27901 cgtggctacg gtaggtttag catactaaca gacaatggct tcacaaaaaa tgggaaatat
    27961 aagctaacac ttagcaaaat gatgcgtaaa taaggagata taatggcact tacagcacta
    28021 gaaattaaag ataaaacgtt taagacaaag tttcgtggct acagtgaaga ggaagtaaat
    28081 gaatttcttg agattgttgt agacgattat gaggctttgg ttcgcaaaaa tcgtgataat
    28141 gaagctaaga taagagagct tgaagaaaag ctgtcttact ttgatgagat gaaggaatca
    28201 ttgagtcaat ctgttatcct agcccaggaa acagctgaaa aagtgaaatc ctcagcaaat
    28261 gctgaagcaa ccaatttggt cagcaaggca acctatgatg ctcagcattt acttgatgag
    28321 tcaaaagcaa aggctaacca actgttgcgc gacgcaacag atgaagcaaa gcgcgttgct
    28381 attgagacag aggaattaaa gcgccagaca cgcgttttcc atcagcgctt ggtttcagct
    28441 attgagtcac agctaagctt atccaattcg cctgagtggg acgaattgtt gcagccaaca
    28501 gctgtctacc ttcaaaactc tgatgcagcc tttaaagagg tggttaaaac tgtccttaat
    28561 gaagatattc ctgaggctga tgacagcaat tcctttgatg caacacgtca gtttacacca
    28621 gaggagctag aggagctgca gcgtcgtgtt gaagaaagca ataaggagct agaagcctat
    28681 caggtgcagc gagaagagca agctagcgag cctgaagtga acctaagcga gacacagacc
    28741 tttaaattga atatttaatc ataagaaaaa caggattgaa tgcccaaaat cacagcaagt
    28801 aggagatgat gagagtccta tattccctga gcatgacaat tatcattttc ttcaatcatc
    28861 actgaatgac agtaagtgac gagggaggct caccttacga gcaaagaggg aacagcaaaa
    28921 gggattttac tgttctgaat taaggtggta ccacgagctt tcgtcctttt tgagacgggg
    28981 ctttttttgt aattctgata agatattgac taaaaggagt ttgacaagat gaaattaaaa
    29041 gaaacactta acttaggcaa aacggccttt ccaatgcgtg ccggtctacc caacaaggag
    29101 ccacaatggc aaaaggcttg ggacgaggct gagatttaca aaaaacgtca agccttaaat
    29161 gaaggcaagc ctgcctttca cctgcacgat gggcctccct atgcaaatgg taatatccat
    29221 gtcggacatg cgctgaataa aatttcaaaa gacattattg tacgtgccaa atctatgtca
    29281 ggctatcaag cgccttttgt tccaggttgg gatactcatg gccttcctat tgagcaggtc
    29341 ttggctaagc agggggttaa gcgtaaagag atggatctgg ctgactatct tgacatgtgt
    29401 cgtcagtacg cgttaagtca ggttgataag caaagagacg actttaagcg tctcggtgta
    29461 tctgctgatt gggacaatcc ttatgttacc ttagatccaa gctttgaagc cgatcaaatt
    29521 cgtgtctttg gtgcgatggc tgataagggc tacatttatc gtggggcaaa gcctgtgtat
    29581 tggtcatggt cctctgaatc tgctcttgct gaggcagaaa tcgaatacca tgatattgat
    29641 tctacatcgc tttactatgc taatagggtt aaagatggta agggaatcct tgatactgac
    29701 acctatgttg tggtttggac gaccacacca tttacggtaa cagcttctcg tggtctaaca
    29761 gttggacctg atatggatta tgtggttgtt agacctgcag gttcagaccg taactatgtg
    29821 gtggcagaag gactgctaga cagtctggct gctaagtttg cttgggaatc atttgagatt
    29881 ttggccaatc ataagggctc tgacttggaa tacattgtaa ccgagcaccc ttgggacagt
    29941 gaggttgatg agctagtcat tcttggcgat catgtgacgc tagattcagg tacaggtatc
    30001 gttcatacag cacctggctt tggtgaagat gactacaacg ttggtatgac atatggactt
    30061 gaggttgcag ttacagttga tgagcgtggt ttgatgatgg aaaatgcagg tcctgatttt
    30121 catggtcaat tttatggcaa ggtaactccg attgttattg aaaagcttgg agacctattg
    30181 cttgctcaag aagtgatcaa ccactcctat ccatttgatt ggcgcacgaa aaaaccaatt
    30241 atttggcggg ctgttcctca gtggtttgct tctgtgtctg acttccgtca agagattcta
    30301 gatgagattg acaaaacaac attccacccg acatggggaa agacacgact ctacaatatg
    30361 attcgtgatc gtggcgattg ggtgatctct cgtcagcgtg cttggggtgt tccactgcct
    30421 attttctatg cagaggacgg cacagccatt atgactaagg aggtaactga tcacgtcgca
    30481 gatctgttcc aagagcatgg gtccattatt tggtggcaaa aagaggctaa ggagctttta
    30541 cctgaaggct tcacacaccc aggctctcca aatggggtat ttaccaaaga gacagatatc
    30601 atggacgtct ggtttgattc agggtcttct tggaatggtg tgatgaatgc tcgtgatcat
    30661 cttgcttatc cagctgacct ctaccttgag ggctccgatc aatatcgtgg ttggttcaac
    30721 tcatcactga ttacctcagt tgcggttaat ggtcatgcac cgtataaggc tatcctatca
    30781 cagggctttg tccttgatgg taagggtgaa aaaatgtcta aatctaaagg aaatatcatt
    30841 tcacctaatg atgttgcaaa gcaatatggt gctgatattc tccgtctctg ggtagcttct
    30901 gttgatacag ataatgatgt gcgtgtgtca atggatatcc taggacaggt ctctgaaacc
    30961 tatcgtaaaa tccgtaacac gcttcgcttc ttgcttgcta atacatcaga cttcaatcca
    31021 catacagata aggtggctta tgctgagctt gctgctgttg ataagtacat gaccatcaag
    31081 tttaacaagc tagtaggagc tatcaatact gcctatgagc gttatgactt catgacgatt
    31141 tacaaggctg tggttaactt tgtgacggtt gacttatctg ctttctacct tgattttgcc
    31201 aaagatgtgg tctacattga ggctgctaac agcctggcac gtcgtcgtat gcagactgtc
    31261 ttttatgata ttttggttaa tatcactaag ctattgactc cgatccttcc acatacggca
    31321 gaggaaatct ggtcatattt agagcatgag ccagaagact ttgtacagct atcagagctg
    31381 ccacaggctc agacttttga taatcaagat actatcctag aggaatggga agcctttatg
    31441 acgcttcggg cacaggcgca aaaggctttg gaggaagcac gtcatgacaa gattattggt
    31501 aagtccttag aagctcatct gacaatttat gcaagtccag aggttaagac actgttgaca
    31561 gctctagata gcgatattgc actgctattg attgtctctc agctaaccat tagtgaggag
    31621 ccagctcctg agaatgctgt cagctttgat gatgttgcct ttacggtagc tcgtgcgcaa
    31681 ggagaggttt gtgagcgttc acgtcgtatc gatccaacga ccagaatgcg gtcttataat
    31741 gcctttgttt gtgaccacag tgcgaaaatt atcgaagaaa acttcccaga agcagtagca
    31801 gaaggctttg actcagctgc taattaagca actaacagct ctgttcccga gttaaataag
    31861 cattggcgtg cttttgccaa tccagcagca aggtgctagt cggtctgggc gtacctgcct
    31921 tactagggac tctttgtgtg ggagctgata agtgacctgc cttgagcttg gcaggtctag
    31981 gcttctttat aggttcacga tttacgattg actgggctta gagaagggct agtcctgcta
    32041 ggcggcattg gatatgaact gagtagtcat catagctata aaaaaacaag cgcagactca
    32101 cgtcagctta atcgtgagcg gcgcttgttt tttcttggtt ggggggtgaa ggcgaggagc
    32161 tattaaagct aatattaagc gatcaaaaaa gcctagacca ctagtcatgt tgtctaagct
    32221 tcagctgtta gagaggagct ttctgagtgg aaggtagcct atgctgatag gtgctgcctt
    32281 agccttttag cagtagtatt aaggctagac agacgtctgg aaggaaattt caatcaaatt
    32341 attggtgtgc agggtttttg agtgacctgg aatcacaata gattggtcaa tcttacgctt
    32401 taagaaaaat tcgcgaatca cttcaagctc gtcctctttg atggcacgat atttatttga
    32461 aatgagtagc tcataatgct tgggtgcttg cgtaaagatg acgtcagtgt taccagctga
    32521 gtaaacttca acgaggtgag catctgtatt ttgcagctga tttctgacaa gctcggggtg
    32581 actgctggtg gtattaataa gtctcataaa tcttctcctg actattttta cttttattat
    32641 agcactattt ttaaattgat tacggatttt aatggtgctt tttctgccat tcttcgacgc
    32701 cccatctgtg gctatcacgc tttaagactg ttatggcgtc cgcaatagga agaaaccaag
    32761 ccagatggtt aaagtcttcc aagggctttg agatagcttg gaatgatgtc acctcgtaca
    32821 ggtaggcagg attatagtag taggtatcgc ggtgacgaga atagaagtat tcgtctgctt
    32881 gaccataata ataaccaata tcagcagcaa atcccagctc ctcaactagc tcacgctcca
    32941 gtgcctgtag ctggctttca ccagcctcta tttctcctcc tggcaaaaac caagcaccat
    33001 ttggagcctg cactaggata atctctgttt tagccgagtt aggaatcact gcatagacac
    33061 cgtaacgtgc ggtgtaatgc tggtcatcta tcttatcacc aaatattgga acggtcatat
    33121 cgcttctcct ttgttttatt atactaaatt tttggtcatt attctcataa aactgtagat
    33181 ttatcaaaaa tgtttcataa aaaaatgctc gtcaaaaaga gagaaaatgc tgtctgcttt
    33241 tctctctgct tttctctctg ctttttggta tgccctgtta gtccgcctgc ttcgcctgag
    33301 atttgactac aggcttgatt ataatgtgtc cattagaggt caagacagct cgcatgtctt
    33361 tttctgctgg gtgctcaagg tagaagtcag taatggcgtc ctcaatgtag tcctgaatgg
    33421 tgcggcgcaa tggtcgtgct cccatcttag gatcatagcc tagctcaacg agcttttctt
    33481 tgaccttttg ggtgacatca aggcgaatgt tattgtgagc aaggcggtgg ttaacatcat
    33541 cgagcattaa atgaacgata tgtaaaagat tgtccttgct tagtggctga aactcaataa
    33601 tgccatcaaa gcgattcatg aactcggggc taaagaaatg actgagctct cctaaaacag
    33661 agtttgtccg cccttctcta gcagcgccaa agcctactga ggcctctgtt ttgccagtgc
    33721 cagcatttga tgtcatgatg ataatagtgt ccttaaagct aacggtacgt ccttgtccgt
    33781 cggttaatcg tccgtcatct aggacctgta aaaacatgtg catgacatca gggtgagcct
    33841 tttcgatctc atctaacaaa atgagcgagt aagggttgcg gcgcacctgc tctgttaact
    33901 gacctgcctc ctcatagccg acgtagccgg gaggggcacc gacaagctta gccacagcgt
    33961 gcttttccat gtattcagac atgtcaaagc gaatcatgtt atcagcagag ccaaaaagct
    34021 caatggctaa ttgcttggaa agctctgttt taccgacacc agttgggcca acaaagagga
    34081 aggagccgat aggacgattt ggggctccca gtccaacacg attacgacgg atagcttttg
    34141 caattttatc aacagcatcg tcttgaccga taacatgctt tttgagatcg gcggccagat
    34201 tgactagctg tgattgttcc ttttccttta aatcaccaac tggaatattg gttttttgct
    34261 caacgattgc ttcgatggtc ttgtcagtga tgattggaat atcctgctca tctagctttt
    34321 gagcctgcat ttctttatat ttggcgattt gatcgcggaa ataggctgct cgctcataat
    34381 cctcatcacg tgtggcttgt gtcttgaggt tttcagcctc aatcaaacgc ttatcaatgt
    34441 ctttggggtc aacaaagtta agggttaggt tcatctttga gccggcttca tctagcaggt
    34501 caatggcctt atcaggcaag aagcggtctt gaatatagcg gttggagagg ttagcagctg
    34561 cttcaatagc cgactggcta tatttgacat ggtgatagtc ctcatatttg ggttggattc
    34621 cttttaggat agtgattgtt tcttcaaccg aaggctcgtc caccttaacc ggctgcatgc
    34681 gtcgctcaag ggctgcgtcc ttttcgatga tgcgatattc attgagagtg gtcgctccca
    34741 ctaattgaag ctcaccacga gcaagtgctg gctttaaaat atttcctgcg tccatgctgc
    34801 cgtcaccaac tgcaccagct cccacaattt catggatttc atcaataaat agaatcacgt
    34861 catggcgctt gcggatttcc tccatgagct tttgcatgcg ctcttcaaat tggccacgaa
    34921 tacctgtccc ctgaacgagg ctaaccacat caaggcgaat cacctgctta ctctgtagct
    34981 tttgtggcac atcgccatca acgatttttt gagcaaggcc ttcaacgaca gcagtcttac
    35041 caacacctgg ttctccgatt aggacagggt tatttttggt acgacggttg agaatctcga
    35101 tcacgcggat aatctcatcg tcacgtccga tgacaggatc aatatcacca cgcttagcca
    35161 tttcagtgat attaatgccg aattcctcaa gcaaaccttt gttagcctct tgtgctggct
    35221 gtgtgtgatt gggacggtag ccattgtgac ctccgccatt atggccgcct gattgggtag
    35281 gtggtgtatt gggcaattga ccgaaggctc taaaattgtt caggtcacca aaaaagtcat
    35341 caaagaaagg gttttgagaa ggctgctgcg ccttttggtt gccattatag cctcctaaga
    35401 taggattttt agggtctgtt ttcatgattt ggtagcaatt ttgacagagg tcaatctgcc
    35461 tttgctttcc gttaatgctt gtataaagat gaatggttga ttcgtttaaa ttacagtttt
    35521 gacaaagcat atcatacctc caaggggtta tctaaaaagt caaggtcatt tagtcaaaaa
    35581 tggtcaaact ttatagtcat attatagcac cttaggcttg gaaatcaagt aaaaagcttc
    35641 attattagca ctttcaggta tagagtgata atctctataa atcttgctgc tcattggttc
    35701 aaaaaagtcg tcaaagggga taaaataaag agaaaatggc tacttttctt gtttgttttc
    35761 gatgatttat gttaaaatat atagggacaa taaacgaata ggagaaacga aatggaatca
    35821 catttagtga gaatcatcaa ccgtctggag ctgatggtaa cagatggcgg taatttaaag
    35881 agaaactttg agcgagatgg tgttgttgtt gcagaggttg catttgtcaa cgatcctgaa
    35941 aatggtccag tctttatttt acgtgatatt gaagcgcgtg agtcatattc atttgatagc
    36001 atcgatttga ttgcgatgga aatttacgat ttgttatatt aagctattga tgatgacatg
    36061 ggcttgctgg gaggcaggtc agacagagga caagctggtg atttactggt ttgtttttat
    36121 tatcccttaa agcctcaaga cagctccagg aaaggccttt ctcctatggt ctttctagcc
    36181 ggtagggctt gatagtgatt aatagtgatc tgctctagca cggtcttgag cttttactgt
    36241 cagaggcttg tgaccttagc cactcgcagt aaagggtact ggcccagtaa gcaaggtagg
    36301 ctaagtatca atgtgaagtt ctaaccttga tcttagtgaa atatttttga ggtgaattaa
    36361 gatgttaaaa gtccttagaa tgctcatttc taagggtttt gttgtgtcta gctgttggtg
    36421 tttgaaagag cggtggtatg ataaagagag gtcagaaaag acctctctga tgtttgtgat
    36481 tagctgttag ctattgccat aggggaaaga cacaatagct agcttagctt ttctttttct
    36541 ttaggtttag gacgcctgcg ctagtgatga cgctaagggc tgcaagggtg aagaatgggt
    36601 gatttgtctc ccctgtagct ggtagcgtgc tcttttgagc tgctggtgct gacttaggcg
    36661 ctggtgcttt aggctgagct gatttttctg gagcctttgg tgcaggtgtc ttttcaggtg
    36721 cttttggagc tgatggtttt gtatcttttc cttgatcacc ctttggtttt tgctcgcctt
    36781 tttcgccgcg ttgtccttgc tcgccttttt cgccgcgttg tccttgctca cctttttcac
    36841 cgcgttgtcc ttgctcacct ttttcaccgc gttgtccttg ctcacctttt tcaccgcgtt
    36901 gtccttgctc acctttttca ccgcgttgtc cttgctcgcc tttttcaccg cgttgtcctt
    36961 gctcaccttt ttcaccgcgt tgtccttgct cacctttttc accgcgttgt ccttgctcgc
    37021 ctttttcgcc gcgttgtcct tgctcacctt tttcgccgcg ttcgcctctg tcacccttag
    37081 ggccggctgg tccttgttca cctttaggac ctgtttctcc ggtttcgcct ttatctccac
    37141 gtggtcccat aggcccaaca ggaccttgct ctccgcgttc ccctctaggt ccggcaggcc
    37201 ccacaggtcc ctgaggacca ccttttttag cttgtagttc taagttttgt aagtaggttt
    37261 gcatgaattg tcttaatgta tgtaggtata ctcttacttc gccatctccg agtccgtccc
    37321 taattagttc agctggatct ggataggact ctaatcgcgt ataatcttca gctcgggcat
    37381 ttccagctgt tcctaggctg gccattgttg ctagggcaat ggctgctgag cagacgctgt
    37441 acttgcgtat tgtttttttc atctttctct cctttgatga tagtatcatt actttttcaa
    37501 aattctttcc cgaagaagag tttaacatgg tagcttgcta tgagaaacag ctaggcgcca
    37561 ctttgtctcc gtagtttttt taattcaatg ctgaatcgtc tgattttatc agagggttat
    37621 tgtttttaaa ggcgaggagt tgctttgctc agctagtcta gcaagttcac aggtcagctt
    37681 atgtttctta tcaagcttgt ttgtttttga gaatattttt cgataaaaag atgttgtatt
    37741 aatattcatg ttatagtata attatattcg ttgccatgac tttatgaatg ttaggagata
    37801 ggaatggatt ttaccttttt acccaaatac tgggcttatt tcaattatgg tgtgcttgta
    37861 accatgatga tttcagcctg tgttgtcttt tttggcacga ttataggtct tttagtgacc
    37921 ctgataaaac gcagtcatat caagcctttg tcttggcttg tcagtcttta tgtctggatt
    37981 tttcgtggaa cgccgatggt ggtacagatc atgattgctt ttgcttggct gcatttcaac
    38041 gatctgccca ttgtaggctt tggtgtgttg gatttggatt tttcaagact gcttcctggt
    38101 attattatta tttccttgaa tagcggtgct tacatatctg aaatcgtcag ggctgggatt
    38161 gaggcggtgc caaaggggca gctggaggct gcttactctc ttggtatccg tcctaagaac
    38221 gccatgcgct atgtgatttt gcctcaggcc tttaagaata ttttgccggc cttgggcaat
    38281 gaattgatca ccattatcaa ggatagtgcc ttgcttcaga cgattggtgt gatggagctt
    38341 tggaatggag ctcagtcggt tgtgacggcg acctatctgc ctattacacc cttgctgttt
    38401 gcggcctttt attacttgat gataacaaca atattgtcgc aattattagg ctgcttggag
    38461 cgcaagctag cacagggagg gagataagat gactgagaca gtgatttcga ttcgtcagtt
    38521 gcataagagc tttggcaagc atgaggtgct aaaaggaata gacctgacca ttaatcaggg
    38581 tgaggttgtg gtgattattg ggccatctgg ctcaggaaag tccacgctat tgcgcacgat
    38641 gaatttgctt gaggtgccaa caaagggaca catcagcttt gagggcgtcg atattacgga
    38701 taaggcaaat gatattttca agatgcgtga gaagatgggc atggtttttc agcagtttaa
    38761 tctgtttccc aatatgacag tgctggaaaa catcaccctg tcacccatca aaacaaaagg
    38821 aatgtcaagg gctggcgcgg agcagagagc ttatgagctg cttgagcgag ttgggctgag
    38881 agataaggct gctgcctatc cggcaagctt atccggtggt cagcagcagc gcattgcgat
    38941 tgcgcgcggc ttggcaatgg atcccgatgt gctgctcttt gatgagccga cctcagcgct
    39001 tgaccctgag atggtgggtg aggttttggc tgttatgcag gatttggcaa aatcaggcat
    39061 gacgatggtt attgtaacgc atgaaatggg ctttgccaaa gaggtggcgg atcgcgtgat
    39121 ttttatggac ggtggtcttg tgattgaaga gggcagtcca gttcaggtat ttgaagctcc
    39181 taaggaggag cggaccaagg actttttgag caaggtattg tcatagctgg cgcagctaaa
    39241 gggcagcatg tcacctcaag gtctggctat tagtcaattg gctgtttgtt ttgggcattt
    39301 tgtttgtaaa aggcttagaa agtctggttg gtgctgtagc catatctggc tttgctacgc
    39361 ttgggctgct agctggtcag tgggtatcat agtgattgga ggtgtggtct ctttattggt
    39421 caacattgct gtggcaggct agcacagggg ctttgcttgt tgtgctgggt aaggggtttc
    39481 atttgcatga ctgttaacat tgcttaattg atgaattagg ttgacttttg ttttattgtt
    39541 tgatactatt caggtaagtc tgtcattaga aagcgctttg cttttttgat gatggaaatc
    39601 atgatcatat gatcacgtct taggtaatat gttgttgtca acatggtggt ctgaaagtag
    39661 gaggataata tggactacaa agctgtttat caggagtggc tgcacaatga ttttttcaat
    39721 gaagaaatca aggcagattt agaggcgatt aagcatgatg aggctgagat tcaagaccgt
    39781 ttttataagg tgcttgagtt tgggacagca ggacttagag gaaagctcgg tgctgggacc
    39841 aaccgtatga atatttacat ggttggtaag gctgcgcagg ctttagctaa taccattatt
    39901 gatcatgggc cagaggcagt ctcacgcggg attgccatca gctatgatgt gcgctataag
    39961 tctaaggaat tcgcagaatt gacctgctcg atcatggcag ccaatgggat caagtcttat
    40021 atctacaagg ggattcgtcc gacaccgatg tgctcttatg cgattcgtgc cttgaactgt
    40081 atctctggtg tcatgattac tgctagtcac aatcctcagg cctacaatgg ctacaaggct
    40141 tattgggaag aggggtcaca gatcctagat gacattgcta atcagatagc ggttcatatg
    40201 gacgctattg agcgctttga ggacgttaag cagataccct ttgaggaggc attggcaagt
    40261 ggtctgacca gctatattga tgatagtata gaggaggcct ataagaaaga ggttttaggc
    40321 ttgaccatca atgatactga tattgataag tcagtgcgtg tggtttatac acctttgaat
    40381 ggcgttggta atttgcctgt tcgtgaggta ttgaagagac gaggctttga tcatgtcttt
    40441 gtagtgccgg agcaggaaat gccagaccca gatttcacaa cagttggtta tccaaatcca
    40501 gaggtaccaa aggcctttgc ttattcagaa agactagggc aagaagtagg agcagctatt
    40561 ctgattgcga ctgatccgga ctgtgatcgt gtggcactag aggttcgagc tgctgacggt
    40621 agttatgtct ttcttaatgg taataagatt ggtgctttgt tgtcctacta tatcttttca
    40681 cagcgtcatg ctaggcataa tcttcctgac aatcctgtcc ttgtcaaatc aattgtaaca
    40741 ggggatttat caaaagctat tgccgctaaa tatgacgttg aaacggttga gactcttaca
    40801 ggctttaaaa acatctgtgg taaggctaat gactatgaca tcacaaagga gaagacctac
    40861 gtctttggct atgaggaaag cattggtttt tgttacggta cctttgtgcg tgataaggac
    40921 gcggttagcg cctcaatgat ggtggtagaa atggctgcct actacaagca aaggggtcag
    40981 tcactcttag atgtgcttca agacatttac aaggaatttg gctattacaa tgagcgtcag
    41041 gtagcgctag agctagaggg tgttgagggg cagaagcgta ttgcacgtat catggaggac
    41101 tttagaaatg agcctattga gcatgcaggt gctatgagct tgaagaccat tgtagacttt
    41161 aaggacggct accttgattt tccaaagcaa aattgtttga aatattattt tgatgatggg
    41221 tcatggtatg cgctgagacc atctggaaca gagcctaaga tcaagcttta catctatact
    41281 attggtgaaa cagaggcaga cagcattgct aagctagacg ctattgagtc agcttgtcaa
    41341 gcaaagatgg acagtgtcag ctaattgttc aagctctgca acagaaaatc agctaatcaa
    41401 taagcaaaaa ggaaaaggaa gtgacagtgc ttcctttttt cgttataata gttaaaaaat
    41461 tagcaaggag tgcatatggt acagattatt gatgggaagg ccctagcaca gaaaatgcag
    41521 gcagcattgg ctaagaaggt agagagctta aaggcagaaa aaggaattgt tccaggcctt
    41581 gttgtcattc tggtaggaga caaccctgct agtcaggttt acgtccgtaa taaggaacgc
    41641 gctgccttag cagcaggctt taaaagtgaa accgttcgct tgtctgattc agtctgtcag
    41701 gaagagttga tagagctcat tgagcaatat aatcaagatg atacgattca tggtatttta
    41761 gtgcagcttc ctcttccgca ccatattaat gacaaaagca ttatccttgc tattgatcct
    41821 aaaaaggacg tcgatggctt tcaccctatg aatacaggtc atctgtggtc aggtcgtccg
    41881 aatatggtcc cttgtactcc ggcagggatt atggagatgt ttcatgacta tggtatcgaa
    41941 cttgaaggga aaaatgctgt tattgtcggg cgctcaaata ttgttgggaa gcctatggcg
    42001 cagctactgt tggataaaaa tgctacggta acgcttaccc attcgcgcac gcgccgactg
    42061 gcagatattt gtcgtcgtgc tgatatcttg attgttgcta ttggtcaggg gcattttatc
    42121 acaaaggagt ttgttaaaga gggtgctgtt gttatagatg ttggtatgaa tcgtgacgtc
    42181 aatgggcgat tgattggaga cgtcgccttt gatgaggtgt cagagctggc tagcatgatt
    42241 actcctgttc cgggtggtgt tggaccgatg accattacta tgcttttgga gcaaacctat
    42301 caagcagctc taagaagggt gagtcaatga ttatagatca atcgtttgtt gctagggttg
    42361 ttgttccgcg gcaggctgac tcccataagg ggagttacgg cagagtactg ttagtaggtg
    42421 gcttgtatcc atacggtggt gctattatta tggtagcgct ggcctgtgtt catagtggtg
    42481 ctggcctagt aactgttgca actgatagag aaactattgc tgccttgcat agtcatttgc
    42541 cagaggcgat ggctattgcg gtagatgatg aggaattact gttatctcag ctaggtatgg
    42601 cagacctgat tttgattggt ccggggctgt cggagaatag cagagcagct aggctgtttg
    42661 aattggtcct tgcacatgtc gctgatcatc aggtattggt cattgatggc tctgccttaa
    42721 ggcttttagc gaaaagggca gctgatgtta agcagctgag gtgccctctt gtgttaacgc
    42781 cacaccaaaa ggaatgggag gcgctgtcag gtttagcgat tgatcagcag tatgatgctg
    42841 ccaaccaagc agctctcaag cattttccaa gggctacgat tttggttgct aaaagctcag
    42901 caaccaagat ttatcatggc aaccagatct accggctaag agtgggcgga ccttatcagg
    42961 ctacaggtgg tatgggggat accttggcag gtatgatagc aggaatagct gtccagtttc
    43021 cagagtcaag cttggtggct aaggttgctt gtgcgaccta tctgcactct gcgattgctg
    43081 atgagctggc aaagactgcc tatgtggttt tgccgactgc tattagctat gagcttccta
    43141 gatggctaaa ggcaatcagc acaggccaga agctaggttg aggctgtgct gcgaggtcgt
    43201 ttgggaaaag cggttaattg gtaggcatga cagcagctgg tttcagtcgt ttagctattt
    43261 tgagtttaga gctgctagct taagactggg tgctgcttta tgattcaagg aagctatcat
    43321 tggaaaaact tgtgtcaagc tgtagaagcc ctagctggct tctttttttg tctctttttt
    43381 gctcactatt tatgtggaaa catgatataa ttgcattagt atacagttgg agcagttagg
    43441 cttcatgaag tgaaaggtaa actgatggca gactatttat ccgtcactca gctgacaaaa
    43501 tatttaaaat tgaaatttga tcgagaccct tatctggagc gtgtctatct cactggtcag
    43561 gtatctaatt tcagaaaaag accaaatcac caatattttt ccttaaagga cgagggagcg
    43621 gtgattcagg ccaccatgtg ggcaggagct tataaaaagc ttggctttga tttagaagag
    43681 ggcatgaagc tcaatgtggt tgggcgtatt cagctctatg agccaaatgg ctcgtattca
    43741 atgatcattg aaaaggctga gccagacggt attggtgctt tggcgctgca atttgagcag
    43801 ctcaggcaaa agctggctgg tgaaggcttc tttgatgaga ggcataagca ggccctgccg
    43861 caatttgtga caaaggtagg tattgtgacg agtccaagtg gggctgtgat tcgtgatatt
    43921 atcacaacca tctcaaggcg ttttcctggg gtgagtattc ttttgtttcc aacaaaggtt
    43981 cagggtgagg gggcagctca agaggttgct gctaatatta ctaaggctaa ccagcgtgag
    44041 gatctggatt tgttgattgt tggacgcggc ggtggctcga ttgaggacct gtgggctttc
    44101 aatgaggaaa tcgttgttca ggctattttt gagtctcgcc tgcctgttat ttccagcgta
    44161 ggacatgaga cagatacaac cttggctgat tttgtggctg atcgcagagc tgccacccca
    44221 accgcagctg cagagctggc gacacctatt acaaaaacag atattgtctc ttggattgct
    44281 gagcagcaga gccggtccta tcaagcctgt ctgcgctata tcagacaagg gcaggagcgg
    44341 gtggataagc tttcttattc tgttattttc aggcagccag agaggctcta tgatgcttat
    44401 agtcaacgct tagataggct tacgacctcc ttgatgacca cttttaaaga gacattatca
    44461 ggagctaagc aggagcactt gattttggag catcgtttag cctctgtcaa tgtacaggca
    44521 aggcttgagc gttatcagga tcgtctggca actgcgcatc gtctcttgat agccaatatg
    44581 accaatcaat atgacagtaa gctagcaggc tttgagcgag ctcaagctgc cttgctgtcg
    44641 cttgatacga gccgtatcat tgcccgcggc tatgccctgt taaaaaagga cggtgtagta
    44701 gctgcttgtg ttaaggacat taaaaaggga gatcatctta gtattatcat gcgtgatggt
    44761 caattagaag tagaggtaga agatgtcaac gaaaaaaata tttgaagagc gtttacaaga
    44821 attagaggct attgtgacga ggctagaaaa tggtgatgtg ccactagaag aggccatctc
    44881 tgaatttcaa aagggtatgg tgctgtccaa ggaccttcaa aaaaccttac aagcagctga
    44941 aaagacactt gttaaggtca tgcaggcaga tggcacagag ctagaaatgg atgcctaatg
    45001 gataagctaa caagaattaa tgccacgatt catcagtatt atgacaggca gtctactgtt
    45061 tcagcagatc tggaggaggc cattttatat tctgttgatg gtggaggaaa gaggctccgt
    45121 ccactcatgt tattggagct gctagagggc tttggtcttg ccttgacaga cgctcattac
    45181 gcggttgctg ctgctgttga gatgattcat acaggaagtt tgattcacga tgatttgcct
    45241 gctatggata acgatgatta ccgtcgcggg cgactaacta gccacaagca atttaatgaa
    45301 gcaactgcta ttttggcagg agatagtctt tttttggacc cttttgctct aatcgcaggg
    45361 gcagatttgc cggctgacct gctggtgcaa ttgattcagc agttttcctt agcgtcagga
    45421 acctttggca tggtcggtgg tcagctcttg gacatgaagg gtgagcatca gctgctggat
    45481 attcaggagc tatctgatat tcatgccaat aaaacaggga aattgttgac ccttcctttt
    45541 gtggctgcgg gtatcatagc tgagcagtca gcagacgttt tgtcttgtct gtgggaggct
    45601 ggtaggcttg ttggacaggc ctttcagata agagatgata tattagacct tacggctagc
    45661 tttgctgatc ttggcaagac accgcaaaag gaccttgctg ctgcaaaatc aacctatccg
    45721 agtctgcttg gtttagagcg ctcaagggct attttggagg agtctttgag tcaagcgcta
    45781 gctattttta gcagactaga aagggaagaa ggctttgagt ctcaggctat tatcaaaagg
    45841 atcgaggggt tgcgactaaa tggctaaaga aagagtagat gtgctagcct atagacaggg
    45901 actttttgaa acgcgagaac aggccaagcg cggtgtgatg gctgggctag ttatatcagc
    45961 tataagtggc ttacgctttg ataagcctgg tgaaaagatt gatgagggga tcgaactaag
    46021 gctcaagggt gagaagctta agtatgtcag ccgagggggt ctcaagctgg aaaaagcctt
    46081 gcaggtcttt gggatctctg tgcaggataa ggtgacaatt gatattggtg cttcaacagg
    46141 tggctttaca gatgttatgc tacaggcagg agctaggctg gtttacgctg ttgatgttgg
    46201 aaccaatcaa ttggtctgga agctcaggca ggatagtcgt gttcgaagca tggagcagta
    46261 caattttcgc tatgcaaagc tagcagattt ttcagaaggt cagccagcct ttgccagcat
    46321 tgatgtgtcc tttatttctc ttagcctgat actgccgaca ttgcactgta ttttgcagga
    46381 aggggcagag gctgttgctc tgatcaagcc acagtttgaa gcagggcgcg agcagattgg
    46441 caaaaaaggg attgtcaagg atagactgat tcatgaaaaa gtgattaagc aggtggcaga
    46501 tactgctctt aattgcggat ttatcgttaa ggggcttgat ttttcgccta tccaaggtgg
    46561 tcatggcaat attgaatttt tggctcattt agtcaaggga aagggctcca aggctattga
    46621 tgatcagctc atacagagcg ttgttagcag tgcacataag gaatttaaac agcatgaaaa
    46681 agagtgaacg attagattta ataaaaaaaa tggttttgtc tcatgagatt gagactcagc
    46741 atgagctatt aaagctccta gctgattatg ggctagagct aactcaggcc actatttcaa
    46801 gagacatgaa tgaaattggc attgtcaaaa ttccatctgg aactgggcgt tatgtctatg
    46861 gcttgtcaca ggatagtggc aagcgggtgg tgcaaaggcc tgcctctatc aaaaaaacga
    46921 ttttggaaat gtctgaaaaa acagcgggct tggagcagca tattcacctc aacgttgttc
    46981 caggcaatag caagctaatc aaacgttatt tgatgacaga cttttcaggt caattgttta
    47041 gcctgattgc agatgatgat agtttgctgt tgattgcaaa atcagaagca gacgctgatc
    47101 atatccgtca ggaattgtcc ctttggatgc agggattggt ctaaaaaata gagagaagcc
    47161 gatgttatta gaaatttcca ttaagaattt tgctatcata gaggaaatct ctttaaactt
    47221 tgaaaacggt atgaccgtac tgactgggga gacaggggca ggaaagtcca ttatcattga
    47281 tgcgatgaac atgctgctgg gtgcgcgcgc aagcactgag gtgattcgac atggtgctga
    47341 taaggcagag attgagggct tcttttcggt tgatgctaat cctcatttag ccgctgtgct
    47401 ggcagaatca gggattagca tggaagagga gttgattctt cgtcgtgata tttttgctaa
    47461 cggtcgtagc gtcagccgta tcaatggtca aatggtcact gtcagcaccc taaaaaaact
    47521 tgggcagttt ttagtggata ttcatggtca gcatgatcag gaggaattga tgcgtccaca
    47581 gctgcaccag catattttgg atagttttgg agatgaggcc tttgaccagc tcaagcagtc
    47641 ctatcagcag atttttgatc gctataaggc tttgcgaagg caggctcttg agaagcaaaa
    47701 aaatgaaaaa gaacatcagg cgcgccttga cctgctggcc tttcagatag gggaaattga
    47761 ggcagcagat ttggttagag gagaagatga cctgcttaac caagaaaggc agcgattgct
    47821 caatcacaaa aagattgctg ataccttaac cagtgcctac ctttccttgg ataatgagga
    47881 cttttccagt ctctcacagg tccgctctag catgaatgag ttgctgtcta ttgaggacct
    47941 tgccccagag tatcagctta tatcagctgg tgtgtcagag gcttattata ttcttgagga
    48001 ggtcacaaag caattatctg ataccatcga ccagcttgat tttgatgcag gcagattgca
    48061 ggacattgag ctgcgtttag acagcattaa tagtctgaca agaaaatatg gcggtggtgt
    48121 gaatgatgtt ttggactact atgccaatat taccaaggaa taccagttat taagcggaga
    48181 tgaccgttcc tctgatgagc tagaaaggga attaaaggtc cttgagaagc aactggtgat
    48241 gactgcctca cagctaagtg acaagcgtca tgccctggct ctagagctag aagccgacat
    48301 caaagctgag ctgagagagc tttatatgga aaaggcggac tttaaggtcc actttacaag
    48361 gtcaaagttt aatcgagaag gcaatgaaag cttagaattt tatatctcaa ccaatccagg
    48421 tgagggcttt aagccgctgg ttaaggttgc ttcaggtggt gagctttccc gcttgatgct
    48481 tgctatcaag gctgccattt ctaaaaaaga ggacaagacg agtattgtct ttgacgaggt
    48541 ggatactgga gtttcaggac gtgtggccca ggccattgct aaaaaaatat ataaaattgg
    48601 cagctatggt caggtattag cgatttcgca tttgccacag gtgattgcta ttgcagataa
    48661 ccagtatttt atttccaagg aaagcaagga ggagtcgaca gtgtctaagg ctaagctgtt
    48721 gacacaggag gagcggatcg aggagattgc gaagatgatt gcaggagctg atgtcacaga
    48781 gacagcaaga aatcaagcgc gtgaattgct aggtaaggac tgagtatcat agcaaaagca
    48841 gaacagtagc tttagagcaa gcttgcctgc tgcacttgtc gctacatgtt cagaatgagc
    48901 cacctgaaag gcaagcaaga aggctagctc ttatgcgtat gctatcagaa gctaagtctt
    48961 tttgtctctt gcattggcga gtgattgatt gataatatta tgataaatag aaggactaaa
    49021 agaatactga ctgaggaggt aaaatgctga aaaaaagaat gggcttggct agtctgctag
    49081 tgttgatgac ctttgtgtat cagtgctgtt cagttactgc tgagcagtat tccgatactg
    49141 aggttgaggt gctgcagatt agcgaggaga aaagccagat catggaaaat caagaggcgc
    49201 ttaaagacct caccacgtcg tctgatcagc taaagaagga agctttaaag cctaaagagg
    49261 cagctaccaa caagagcaag caagaggctt cgacagttta tttagctgag gacgatcctg
    49321 taaccattga tagctctgac gaggaaagca atcaagatat catagcggat tctgttcctg
    49381 atttggttat taaaggtgat caggtggatg tatctgaggt tatggtctct gtaaaggagg
    49441 attcatcgaa agttgctaag caaagaactg acgcagcgca gcggtacagt atagccaagc
    49501 atcaattgac ccaaaagctt gaggccttta atgcggcaac ggaccaattg ctgaccatga
    49561 ttgctaaaaa atctgatttg actggtcagt attatgtggt tgggcattcg ttgggagaaa
    49621 tgctggctgc tcaaaatgag aaaaagcttg ctgagcaatt agtcatgcaa caaaagcaca
    49681 aaaaaggctt aggctcatca gtcactattt tagacgaatt aggacgtgtg atttctgaca
    49741 ttagtggtca taaaggcatg cttcctttta atcgtaagat cagctttaag gtacatcaag
    49801 tcagatacga tcttccacta actggtgatc gaacagtgct acctgcccag ctggctggct
    49861 tactgctttt actaataggt cttatgctgc ctaaagtagc taacaagaaa agctaagata
    49921 tggtcttggc ttttttatct tttaagaggg tgagtttttg acagatgttt tagctaacac
    49981 caagagctag ataccagctt tgctttattt ttaaaggagt gataaaataa agagacgata
    50041 aatgaggtta gaaatggaac ttaagatggg aactattaaa attgttgcag attcatcaat
    50101 gacgattgaa ccagagctaa tcaaatctct tgatattacg gttgtaccgc tttctgtcat
    50161 gattgatagc aagctgtatt ctgataatga gctaaaagag gaagggcaat ttctacagct
    50221 gatgagagct agtaagtcat tgccaaaaac tagtcagcca ccggtagggc tttttgcaga
    50281 tatttatgag cgattggtca aggagggggc gacagctatt gttgccattc acctctcacc
    50341 agctctttca ggaacaattg aggcatcacg tcagggagct gaaattgcag cagcaccagt
    50401 tacggtattg gactcaggct ttacagatca ggctttgaag tttcaggtgg ttgaagcggc
    50461 tagactggct caagctggcg ctagccttga ggaaatcctt gaggcggtag aggatattaa
    50521 acgaaagaca gagctttata taggggtatc agcacttgag cacttggtta aggggggacg
    50581 aatcggtcgt gtgacaggct tgcttagctc cttgctgaat attcgtgtgg tcatggaaat
    50641 gaaaaatgat accctgcaaa cacttgttaa aggacgcggc aataagacct ttactaaatg
    50701 gctggatagc tatctagcag aaaatagcca gcgacagata gctgaggtgg ccatttccta
    50761 tgctggtcag agggattttg ctgatagcct gaagaagaca atcgctacgg tctttgatgg
    50821 gccaattact gttttggaga ctggctcaat cattcaaaca catactggcg agggcgcttt
    50881 tgcggtgatg gttagatatg aataagcgag ggtttttggg aggccttatc ttctttttca
    50941 gtgtttttgc cttatcattt gtgatattag ctgtccttat tccaaagtct gacccacagc
    51001 tgaagaaaag tgattttcta aaaaataaga agataagcct caattatatt gctattggag
    51061 actccttgac agagggagtg ggtgatctca ccaaccaagg aggctttgtg cccttattgt
    51121 ctggtgatct tggagactac tttaatgcta ccgttaatac tgaaaattac ggtgtttccg
    51181 gtaataccag ccagcaaatt ttaacgagaa tgactgagaa caaggagatc acagagcagc
    51241 tcaaaaaagc taatctcatg acattaacgg ttggtggcaa tgatgtcttg gctgttattc
    51301 gcaagaactt agctaatctt aaggtatcaa gctttaaaaa gccagcaagg caataccaag
    51361 agcgcttacg caaaatcctt gatttggcca gaaaggataa tcaggatctg ccgatctttg
    51421 ttttaggtat ctacaatcct ttttatttga attttcagga gctaacagaa atgcagacgg
    51481 tcattaatga ctggaacaaa aaaacacaag aggttgttga tgactatgac catgtttact
    51541 ttgttccaat taatgatcta ttgtacaaag gagtagatgg taaagagggc attgtccagt
    51601 caacaggaga gcaaacaacg attgtgaatg atgctttgtt ttcaggggat cattttcacc
    51661 ccaataacac aggctaccaa atcatgtcag acgcagtaat ggagacaata agaaagaatg
    51721 gaaaagaaat taaaccttaa ttggtggaaa tgggcttttt tgctattatt ggcttttaat
    51781 gcagcctttt tagcagttat tggaagtcgt attatacaaa taagagagcc taagtctgag
    51841 ctgatcaatc aaaaagcagc aaagaatatt aaaataggga ccttaacaac cactaaagag
    51901 caattaaatg aggcagtcgt tagctaccta aaggattttc agacggaaaa aatgacctat
    51961 aaggtgtatg ccacctcctc gaccattctc tttgaaggaa cctatcagct cttaggatat
    52021 gaggtgccgt tatacattta ttttcagcct catcgcttaa ccaatggtgc gatacagctg
    52081 caggttctct ccttttctgt ggggaccctt tctttgccgg aaaaggacgt tttgcaatac
    52141 ttgaaatcca gctataagct gccaaaattc gttgaagtct tacctaagca atcggctatt
    52201 attatcaatc tacagcaatt ggaaaatgat gccaacatct atttaaaggc tcaaaagatt
    52261 gatcttgtca aggatgatat tcgatttgac atctataaga aatgagtcta actaacgttt
    52321 aatacttgac ctgtggctgt tttttagata tgataatatc tgttaaagcg ttaagcttac
    52381 taattatttg gaggattgtt aaatggctaa caaacaagat ttaatcgcaa aggttgcaga
    52441 agcaactgag cttacaaaga aagattcagc agcagcagtt gacgctgtct tttctgcaat
    52501 cgaagctttt cttgctgaag gtgaaaaggt acaattaatt ggttttggta actttgaggt
    52561 tcgtgaacgc gctgctcgta aaggtcgcaa cccacaaact ggtgaagaaa ttgaaattgc
    52621 agcttcaaag gttccagcat tcaaggctgg taaagctctt aaggacgctg taaaataata
    52681 aatcaaaaaa agccctatct cattaagctg tttagcctgt gagatagggc tttttccatt
    52741 aaggaaggag tcttgtttca ataagtaatc ttgtgtgatc gtctgaaaga ttagcgccaa
    52801 taatttctaa tgtgcactgt cttgggaaca agagttccat ttcataagga taaaatgagt
    52861 agggctgtac aaaagcagcc tggctgcctt gagggacctg aattcttaat tccactgagc
    52921 gatgtggcat agcagcattt ttgatggctg tagtactcat aaagccttgc tttgtataat
    52981 gagtgcctgg cttgatcgct gataggatct gcggatcaaa ggtcttatca tggtagtaac
    53041 gagcgagttc ctcttcagaa gtgcccaatt ctgttaagaa tgtttcataa acatagcgat
    53101 agacgatgat attccaaggg atggttagct tatgagtagc actatcaagt aaggctacag
    53161 actgctgcag ctgggcatcc aactggctgg tatctcccat cacctgttct agggctaggt
    53221 taatagggct ggcagaggcg tatgtatact gatacatcat ctttttttct gcttctgtaa
    53281 aggctgtttg agacctccag cgattggtga taatgtattt ggtaacatca ggctcactaa
    53341 atttataata aggcttaaag ctattcccat agggctcaaa aacaactgtt tgtccttcat
    53401 cataagactg tgccttgatg gttgaaggct gaacgacaag caacgataag aaaaatgtaa
    53461 acaagcatag tgtacgaata gctatccttt gataagataa ctttgcgtta tgatgttgat
    53521 gagtcattta gcttttcctc ctttacagta gtgccaagag tgtcatcacc taatgatgat
    53581 gtctgttgct aacaggatta gccttagttg aaatgattac aaacttcctt aatgtaacaa
    53641 acataataaa aataaattat ttttttatta tatattagtt aagctcagat gacaagctat
    53701 ttgatttttt tctgagataa tgttacaagg gatttctaac accaatgact aactcagatg
    53761 aagggctttt tcttggagga ttgcctatag ttacaatagt aggcaagact ggcagtcgcc
    53821 atgataccta ttccaataac agcaaaggtt gctagatgaa cagaggctgg tatacaggtc
    53881 atgatggtag ttgccagtgg cattaagaga atagcagttg tgacgattga gctaaagact
    53941 cgtcctagca atgcctcagg aacttttttt tgaacgatag aaaagaagtg aatgttaaag
    54001 attgttaaaa agcattcaaa ccataaattc ccaagggcaa tcacaatgac tggaagcttc
    54061 aagagagcca tagctgttat tagaagcatc cctaggccac taaggcctag ggataggagt
    54121 aagctttgct gattattttt aaagagcttg ttagccataa aagctcctaa gatagcccct
    54181 aaagctccca tcgaaagaag actagcatag cttgattggc tgcctagcag ctgattcgaa
    54241 aaaggaatta aataattgaa agcagcaata aagaaattca caagagaagc aataatcaac
    54301 aaagaaaaaa tgtcattgtc atggtagatg aattgcagcc cctccttaat atctgttaaa
    54361 agctgaagcc tattgccttg gctgctctgt ttagtgatgt gcctttcttt gtccttgatt
    54421 gtatatagac atagaaagga caatagaaag ctaatgctat ctagagccaa ggctgttttg
    54481 atgccaaagc aatccatcac taaaaaagca agcattggtg aggaaatact gatgatttga
    54541 gatacgattt ctagctgagc attgaaatga acaagtcttt ctgtttcaac tagtgtgacc
    54601 acataggctc gaaaagcagt tccagagaag gcatacgata ttgctaaaag agcattaaca
    54661 gtgataagcc cataaagcat gatagtaggg ttagctatca gggctaaaag tccgcagctg
    54721 atagctccga tagcatctgt ccacaataac aattgtcgtc gtttataacg atcagcaatg
    54781 gcgccaccga taggatttaa gatgagtgaa ataaggcctt cagctagctg ataataaccc
    54841 aaatattgtc ggccagttgc tccgagtcca gcaatcccgc tgctgttgct gtagtcgtaa
    54901 acagtattgc ctattttgtt aatagctcga cttgcgagca gctggtagtc gtttttgcgc
    54961 atgataaaac ctccaaaaga ttatgtggtt ttattataaa tcagtttttt agggtcttat
    55021 gtttttttgc aaataaggct agaggaggct acaaatcttt caaaatcctt ttggtaattg
    55081 tgcgctaggt gaggacaatc caggctctca aaaatggaaa tagcagtagt catatcctta
    55141 atgccagaca aacactgtcc tctttggtag tcctctaagc cctttaaaaa taaaaagatg
    55201 gttttttcat atagcttggt ttcattattg agtagggcta gtatctgctt ttgataatag
    55261 cgcgcatagt caagctgatg tcggtggata caggtttccc aaatattgag aagggtgatg
    55321 gtaaccaaat gcttattggt tgaaatgctt tcgtagtagg tatgattgtt tagaatttcc
    55381 tttcccattt tatctaataa gggaatatca ataaaaagat agagatttcc aattaaaatc
    55441 agctcataga tatgccagct ttcagtccta aaaaggtagt cagtgacctc atcaagataa
    55501 gccttaggaa aaggaatgct aggattgcat ttacagataa agccttggag tagaatgctg
    55561 tttaaatagt aacgattggt atcaggatca gcttggtgct ttgccaattc ctgcttttgc
    55621 agctgcttga atccctcaat atcgcgtgca tattccagct tgatcagctg cgacatgaat
    55681 tgaatttgct ctgtctgttt gaagttggca gctatgtcca taaattcgct gatttccact
    55741 tgcatgctgt ctaaagctgt taaaaacttt gttactgata gatcagattc gccgcgttca
    55801 aagcgggata actgagacaa ggacacgtct ttactggcaa gctgctgtaa ggtgatattt
    55861 ctgttttgtc taatgctgcg aaatgctttt cccaactgat gattagtcat attttttcct
    55921 cctctaatga gtatatcatg taaggcttct gttgctgtat tttcccgtat gtgcaaacct
    55981 tgaaacttgt ctgctgccgc cacaaaggca tgaaaacatt tacacttttt gatagctatt
    56041 tttatcattg atgtagtctt tttcgcaaca tttgtacggg atcatcagat taaaattaag
    56101 aaactgatga tgtgacactg taaacatgct aaaaatatgt tgaacaatgc ctgtagctgg
    56161 aaaatgggta catgtatttt cttcatgcct gcgtcgtgac ctgctgctat taaagcttgc
    56221 ttgaaaggga aaaagagctt ataatagcag tgagaacatt aaaaatgaaa gtagagatat
    56281 gccaataatt gttatccttg gacttgctat cttttcggtg gttaaggtca ttatttttct
    56341 atgcttttat aaagcatttg agaaaaaaca actaaagaag ctagaacagg atcaaaaaga
    56401 aaccaagcag gcgattgacc aagaggagtc aaaaaaagcc tttccctttt aacataaagc
    56461 tagaaaaagt ctgagacctt tcgtctcaga ctttttttaa ggcttatatt gtaattgacc
    56521 acgaaaatcg tctagtgtct ggtagccctt ttcagccata atgtcttgta gctccttagt
    56581 gatacgctta aaaatagctg gaccttcctg gtgcagtgct gttccaattt gtaccatagc
    56641 tgcgccgcat aggatatgct caaaggcatc acgtcctgtt ttgacaccgc ctgtgccaat
    56701 gatctgaata gaagagttaa gccgttggta aaaggcatga acattagcca gggcagttgg
    56761 cttgatgtaa tcaccaccaa taccaccaaa gccgttttta ggcttgatga cgacctgctc
    56821 atcatcaata accaagccat tgccaatgga attaacacag ttggcaaagg ctaaggggta
    56881 ttgattgaaa atggctgcgg cttggtcaaa atggacaata tcaaaataag gaggtagctt
    56941 gatgcctaga ggcttggtgt aataggaaaa gatctttttt aggagctgat ctgtggcttc
    57001 aaagtcatag gccagctgag gcttacctgg gacattaggg cacgacaggt ttagctcgac
    57061 aagtccttga taatcagagg cctgaatagc ttttaggata gtctcggttt cttcagcaga
    57121 catgcccaca acagataaaa agtggtgctt gcttgcttga tccttttgca tttctgtgac
    57181 aatatctaaa taatactggt agccatgatt aggaagtccc attgaattga ttgagccaag
    57241 tgctgtatct gcatagcgag gctcagggtt gccctgtcga ggggctagag tacctgtttt
    57301 tgtcacaaag gacccagcct cagaggcctc aatggctagc agctcttcct tggtcatgca
    57361 atacactcca gcagcgttca tcaggcaatt attaaaggca aatgtagcga tttttgtggc
    57421 agtagaaacc atgttttcct ccatttttag acaaattttt tctattctat cactagggca
    57481 tgagaatagc aaggcatttt tgcaaaatac ttgcttgaag gctttctttt gtgaggtttt
    57541 agcgtttttc atgatattaa caaaatgatt ttcaataaag agaggaatag actagctttt
    57601 ttgacctatt ttttgtaaaa taggagttgt aaaaaggcaa gaagccttta aacttaataa
    57661 ggagatatta actaatggta aaattggttt tcgctcgtca tggtgagtca gaatggaaca
    57721 aagcaaacct tttcactggt tgggctgacg ttgatttgtc cgaaaaggga acacagcagg
    57781 ctattgatgc tggaaaattg atcaaggaag ctggtattgc atttgatctt gcctttacat
    57841 ctgtgcttaa gcgtgctatc aagacaacta atcttgcact tgagtattct gatcagcttt
    57901 gggtacctgt tgaaaaatca tggcgcttga acgagcgtca ctatggtggc ttgactggta
    57961 aaaacaaggc agaagcagct gagcaatttg gtgatgagca ggttcatatc tggcgccgtt
    58021 catacgatgt gttgcctcct gatatggcta aagatgatga gcattcagca catactgatc
    58081 gtcgttacgc tcatcttgat cattctgtta ttccagatgc agaaaacctg aaggtaacac
    58141 tagagcgtgc ccttcctttc tgggaagata agattgcacc agccttagtt gatggtaaaa
    58201 atgtttttgt tggagcacat ggtaactcta ttcgtgccct tgtcaaacac atcaagcaat
    58261 tatcagatga cgagattatg aatgtggaaa tcccgaactt cccaccgctt gtgtttgaat
    58321 ttgatgacaa gctaaatctt actgctgagt actacctcgg tggtgaataa tgctgtgagg
    58381 ccagacctag ctctggcttt ttttgttatg tgataaaaaa ggcgtttcca acagaaatgt
    58441 gatatgatag ttaaaaagtg gtaaaagaag ggaatcttat gaaagtaaag gaacgccgag
    58501 aagctattac agataggtta agccaagcac aagaagccat ctcagcaact agcttagcca
    58561 aggcattggg agttagtcgt caggtgattg tcggagacat tgccttactt agggcgcagc
    58621 agcttgacat tatttcaaca ccaaagggat atatcctgtc aaatgctttg tttagtcatc
    58681 actattctgc tagaattgtt tgccagcatg gacctgagca gacaaggcag gagttggagt
    58741 tgatattagc acatgatggc attgtgacca atgtggaggt agagcaccct atttatggca
    58801 tgctgacagc accgcttaac attaaaagct cagctgatat caataacttt attgaaaagc
    58861 tcggagcctc taaggcagaa ttattgtcgt ctttgacaga gggtctgcac actcaccttt
    58921 tgtcctgccc tgatcaggag gcatttgaag agatcaagag agatctagca gctgcaggca
    58981 ttctctatgg tgaacaataa tctgatagca gctggcttca cagggattta gtcttggctt
    59041 gatagccaat gtccctcttt tgtcgtaggt gatagggacc gcaggacagc tcctagatgc
    59101 tgaggccaaa gtcttgtggc tgggcctcaa atgaggttaa aagggaagga agctgctatg
    59161 gttatggtga aagggctaga tttaccctta cttttttgct aggataatct tttatgctgt
    59221 taggccgcag ggcttggtgc tgcaatggct gagatgtgtc tgtcttttgt cttagctttt
    59281 ggtgcttgag aagggctggg attgagctta tgctgtggtt gttttttgat ttgctaggtg
    59341 tcttgacatc tgtcgcgttt ttggttatac taacgactag taaaaggaga tattatgacc
    59401 aaaaaaccaa cacaactgat tgcctactct tctattttgg tggcctttgc catcttgatt
    59461 ccgatgataa tgcccattaa gcttattatt ggcccggctt cctttaccct agctagtcat
    59521 ctgcccttgt ttttagccat atttatatcc attccggtag cgatcttggt ggggatagga
    59581 acaggtctgg gctttttgct agcaggattt cctatgatta ttgttatgcg agccttctca
    59641 cacgtgcttt ttgcagctat tgcggctttt atgctcaaaa ggcagcctaa atggctggaa
    59701 acaccgttaa gaacctttgt ttttgggatt atagcaaatg tgattcatgg cctagcagag
    59761 tttttagtgg tttatctgat gacagcaaca gcagcaactg atctttctta tttttggtca
    59821 atgctaatgc ttgttggctt tgggtctttg ctgcatggta tggtggattt ttatctagcc
    59881 ttatttatct ggcgcttctt aaggcagaag ggtcatctat cagtgacaag ctaggatttc
    59941 tgtgagtatt tatgttttag tagccaaggc tgttacaggc tgaggctctt ttttctgaaa
    60001 gcgcttgcat ttttttgaaa aaatgctata ctaaagagtg cgtttgtaaa tatactaaca
    60061 aaaggagatg tcatgaaaac accagaacag atattagccg cgacgattac gattggtgag
    60121 cataaggttg caaagccttt tttggctaag gctattttag gctttattgg cggtgcgatg
    60181 attagtttgg gctacttatt gtatgttagg attgcagcta gtgggctgga gacctttggc
    60241 gctttttcta gtattttggg tgcttgtgcc tttccgattg ggctgatcat tattttgatg
    60301 gctggcggtg aattgatcac aggcaacatg atggcggtgt cggcagcctt ttttgcaaaa
    60361 aagattaagg ccaaggactt gatggccaat tggctggtga ttaccctttt taatattttg
    60421 ggagccttgt tcgttgcctt tgtttttggt cattttctgg gtctgacagc tactggcagc
    60481 tttaaagaag aggtcattga ggtggcccat gccaagcttg ctgcaactcc tctacaggct
    60541 attgtttcag gaattggctg taactggttt gttggcctgg cgctttggct gtgctatggc
    60601 gctagtgatg cgacaggtaa gctccttgga acctggtttc ctgtgatgac ctttgttgcc
    60661 cttggttttc agcatagtgt ggccaatgcc tttgttattc cggcggctat ttttgagggt
    60721 ggcgccagct ggatcgattt tgcgactaat tttgctctcg tttatgtggg caatgtcctt
    60781 ggcggtgcta tctttgttag tctcttttat tacaaggctt atgatcactc taaggaagcc
    60841 tgattagtgc tgttatattt ttagactggg agaccttatt ctcagtctta tttttatatt
    60901 ttgtgataaa ataggaaacg acgtttaaaa aggaggagtt gataagcatc taatatggca
    60961 tcatggataa aaaagaaaaa agcaagcatt cctaggcgaa ttcatctcct ttttttggtg
    61021 attgtttttt tgtttgttgc cctgattttg agattggcac aaatgcagat ttatgagaag
    61081 gatttttaca aggcaaagct gacagcgtca accgtttaca aagtaaaaag ctctatgcca
    61141 aggggaacca tttttgaccg taatgggaag gttctagttt ctaatcgtat caaggacgtg
    61201 gtaacctata cgagaagtcc caaggctagt gctaaggaca ttaaggcttt ggctcatcag
    61261 ctagctgctt atattagcta tcctgaggct aaagtgacag tcagagccaa aaaggattat
    61321 tatttggcag atccagaggc ttatgctaag acggttcaag ccttacccca aaaggacaag
    61381 gtggatcgct ttggtaataa attagtcgaa gcacagatat atcaaaatgc ggcagcctct
    61441 cttaaggaaa cagacttgac ctattcagac caagagctaa aggttattgc tatttttaac
    61501 caaatgaatg cagcagctgt ttttagcact gtaaagctca aaacatcagc cttatctgag
    61561 caggatattg ccatcattat ggccaataag tcaaaattac caggtatttc agttgggaca
    61621 gactgggagc gtcaggtgga ggagacaagc cttgctgcta ttattggaag ggtctctagt
    61681 gaggaagccg gtcttccaaa ggaagaagca aaggcttatc ttaaaaaggg ctattcgctt
    61741 aatgatcgtg ttggaacctc ttatctggaa aagcaatacg aggaggtcct tcaaggaaag
    61801 catgaaatca gagaaatcaa aacgagcaga tctggtgagg ttatttcaga taaaatagtc
    61861 gaaaagggtc agatggggcg gaacctgaag ttgagcgtgc cacttgattt tcaacagggc
    61921 gttgagcaga tcttgaatca gcacttccag acagagctca aaaatggtca ggctgcttac
    61981 tcagaaggga tctatgctgt ggcgcttaac cctaatacgg gagcgatttt agcgatggca
    62041 ggtctatcac acaatcccaa aaccggtgag cttcaaaagg acgctttagg gactattact
    62101 gatgtgttta cacctgggtc tgttgtcaag ggggcgacct tggctgccgg ctggcaggct
    62161 ggagtgattc aggggaatca ggtcttgatt gatcagccga ttcaatttgg tggctcccag
    62221 ccgattaatt cttggtttac cagcggtcag caccctatta ctgctagtca ggcgctggaa
    62281 tattcatcaa atacttacat ggttcaggtt gccttaagaa tgatggggca ggattacgtg
    62341 actggtatga ccttggccaa tactggtatg aaggaaacca tgaaaaaatt gcgggcagcc
    62401 tatgccgaat ttggcatggg agtggcaact ggcgttgatt tgcctggcga atccagtggc
    62461 tacctcatag atcaatataa tactgcaaat gttttgacag aggcctttgg tcagtttgat
    62521 aactatacaa ccatgcaact ggcccaatat gtctcaacta ttgctaatgg cggcagtcgc
    62581 cttgcgcctc acattgtaga aggcatttat caggataatg accagtcagg accaggtaag
    62641 ctaagtaagg ctattgagac taccttgtta aacaaggtgc acttagctgc tgatagttta
    62701 gcgattattc aggacggttt ttatcaggtg gtcaatagcg gtagtggcta tgctacaggt
    62761 agggctcttg caggaggtcc tgttaccatt agtgctaaaa ccggtaccgc agaaacctat
    62821 gctaaggata aaaatggtca ggctttatct acctttaact tgaatgttgt tgcctatggt
    62881 ccgagtgcta gtcctcaaat tgctgttgct gtcatgtatc ctcatgcgac agactctcta
    62941 gccaaggcac atcaatacgt ggctaaggat atcattaatt tgtacatgaa gatgtataaa
    63001 aaccaataaa ggagaaacga gtgctttacc ctataccaat cgcaaaatta attgaaagct
    63061 attctaaatt accagggatt ggtgttaaaa cagcgacaag attggctttt tacaccattg
    63121 gaatgtctga tgaggatgtg aatgattttg ccaaaaattt attagcagct aagcgagaat
    63181 taacctattg ctctatctgt ggcaatttga cagatgatga tccctgccat atttgcacag
    63241 atagcagtcg ggataaagag atcattttag ttgttgagga ttccaaggac gtttctgcca
    63301 tggaaaaaat tcaagaatat catggctatt accatgtgct gcatggcttg atttctccca
    63361 tgaatggggt tggcccagat gacatcaatc taaagagcct aatcacgcgt ttgatggctg
    63421 gagaggcaac agaggtcatt gttgcaacga atgccacagc agatggagag gcgactgcga
    63481 tgtacatctc acgtctccta aagcctgctg gtatcaaggt gacgcgattg gctagaggct
    63541 tggcagtagg atcagacatt gaatatgctg atgaggtaac cctgctgcga gcgattgaaa
    63601 atcggacaga attatagctt agcccatttt cagctctctg tcattagccc ttatgccatg
    63661 tgataaggcc ataaaggaag gcagattttg tcagagtctt ttgaaaagca agctcgtttt
    63721 tgttataata agtggtagtc taattcagat agggaaggtt atcaatgtct aaacaaacct
    63781 taattttatt atacggaggg cgttcggcag agcgtgaagt atcagtgctt tcagctgaga
    63841 gcgtgatgag agcagttgat tacaccaaat tttttgttaa aacctatttt atcagccaga
    63901 caggtcagtt tatcaagaca caggaattct ctagtcggcc gaccttaaca gaaaggctga
    63961 tgaccaacga cactattagg ctagagcagc agataaggcc tagtgatatc tacgaggagg
    64021 gggctgttgt ttttccagtc ttgcatggcc ctatgggaga ggacggttct attcaaggct
    64081 ttttagaggt gctaaaaatg ccttatgtgg gaactaatat cctctcatca agtgttgcaa
    64141 tggataagat taccaccaaa agggtcctag agtcagctgg tatcccacag gttgcttata
    64201 ccgtttatat tgaggggcag gatttagaca ggtgtctggc agagactgag gcagtcttaa
    64261 gctaccctgt gtttgttaag ccggccaata tgggctcatc tgttggtatt tctaaggcag
    64321 aatcagagga ggagttgcgt gcagctatcc tgttggcctt gacgtatgac agtcgtatcc
    64381 tgattgagca aggggttttg gcaagagaga ttgaggttgg actgcttggt aataccgatg
    64441 tcaaatcaac ccttccagga gaggtagtca agaatgttga cttttatgat tatcaggcca
    64501 aatacattga taatgagatc acaatggcta ttccggcagc tattgacgaa tcagctatga
    64561 caagcatgcg tacctacgca gaaacagcct ttaaggctat tggtgcttgt ggcctgtcgc
    64621 gttgtgattt cttccttggt caggacggtc agatctacct caatgaatta aataccatgc
    64681 ctggctttac gcagtggtcc atgtatccct tgctctggga gcatatggga ctgagctatg
    64741 ctgagcttat tgaggagcta gtcagattag cacaggaaat gtttgaaaag cgtgaagggc
    64801 atttaatata agagacaaag gacggaagga gatatagcaa tcctctgtcc tttcgtttgg
    64861 cctgattggt agcgtttttt ggtcagaagc ctttaaagcc ctatcgtcta cggttggctg
    64921 tgccagcttt agcctgtcta tgaaggatca gcctgtaggc ataaagtgaa atagaaagaa
    64981 tattcctaat atgtt
//
LOCUS       DARYXW010000002        58385 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.002, whole genome shotgun sequence.
ACCESSION   DARYXW010000002 DARYXW010000000
VERSION     DARYXW010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 58385)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58385)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58385
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.002"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            <1..153
                     /locus_tag="TV191_000063"
     CDS             <1..153
                     /locus_tag="TV191_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="HEL1506621.1"
                     /translation="EKQNSLTQFQELNSSELNQITGGDWWSEILNFNRSQKYKHTSVG
                     SNNIIV"
     gene            complement(335..800)
                     /gene="tnpA"
                     /locus_tag="TV191_000064"
                     /pseudo
     CDS             complement(335..800)
                     /gene="tnpA"
                     /locus_tag="TV191_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775157.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(1087..1560)
                     /gene="tnpA"
                     /locus_tag="TV191_000065"
     CDS             complement(1087..1560)
                     /gene="tnpA"
                     /locus_tag="TV191_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018373723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HEL1506622.1"
                     /translation="MAKTSYSLSHTKWMCKYHIVFTPKYRRKSIYYKIRQDLIDIFRH
                     LCQYKGVEIIEGHMMPDHVHMLVLLPPKLSISDFMGYLKSKSALMIFDKHANLKYKYG
                     NRKFWARGYYVSTVGLNKRTVAKYIREQEKNDIALDKLSVKEYEDPFSDGSFKTR"
     gene            complement(1842..2207)
                     /gene="rplL"
                     /locus_tag="TV191_000066"
     CDS             complement(1842..2207)
                     /gene="rplL"
                     /locus_tag="TV191_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEL1506623.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     GGAEEATKDSFDVELTSAGDKKVGVIKAVREITGLGLKEAKGLVDGAPANIKEGVAAA
                     EAEEIKAKLEEAGATITLK"
     gene            complement(2272..2772)
                     /locus_tag="TV191_000067"
     CDS             complement(2272..2772)
                     /locus_tag="TV191_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEL1506624.1"
                     /translation="MSEAIIAKKAEQVELIAEKMKAAVSIVVVDSRGLTVDQDTVLRR
                     SLRESGVEFKVIKNSILTRAAEKAGLDELKDIFVGPSAVAFSNEDVIAPAKVINDFAK
                     TAEALEIKGGAIEGVVSSKEEIQALAALPNREGMLSMLLSVLQAPVRNVAYAVKAVAE
                     SKEGAA"
     misc_feature    complement(2801..2936)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(3068..3709)
                     /locus_tag="TV191_000068"
     CDS             complement(3068..3709)
                     /locus_tag="TV191_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEL1506625.1"
                     /translation="MIEKGKFIASWLWLLALAVLITIYLSWLLYPIEVDYLQLEQAVL
                     MCKKSILHNYNILLTYLTNPFVRELKLASFSASRAGLKHFTDVKMLFHITQLIFSLLM
                     LPTIIYFYQSIKKGRVMLLRRGLIAAALLPIVIACFALMIGFDQFFTLFHQILFVGDS
                     SWLFDPLTDPVIWILPEAFFGHCFALFFFIYEMILWSLIGLSYSNQSSQVAYH"
     gene            complement(3706..4473)
                     /locus_tag="TV191_000069"
     CDS             complement(3706..4473)
                     /locus_tag="TV191_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEL1506626.1"
                     /translation="MPYKAYLIDLDGTIYQGKNRIPAGERFIKRLQEKGIPYLLVTNN
                     TTRTPEMVQEMLANQFNVHTGLETIYTATMATVDYMNDMNRGKTAYVIGETGLKSAIA
                     EAGYTEDTENPAYVVVGLDTEVTYEMLSIATLAIQKGALFIGTNPDLNIPTERGLMPG
                     AGALNALLEAATRVKPVFIGKPNAIIMNKALEILKVPRSEVAMVGDNYLTDIMAGIQN
                     DMATILVTTGFTKAKEVPSLPIKPDHVLASLDEWELL"
     gene            complement(4473..5225)
                     /locus_tag="TV191_000070"
     CDS             complement(4473..5225)
                     /locus_tag="TV191_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEL1506627.1"
                     /translation="MGLRYSESLKLSFDFCDVKADVKLPLLLAHCLMVSARQSAEIGR
                     GNEVLLQQYGLIWVVTDYDVTIDRMPRFGETVTIETQAISYNKLFCYRQFHIYDQAGH
                     AIMTILSHFALLNPQTRKAAAIPDDLVVPYQADFVKKIKRPIKIDELQDPMVQAYQVR
                     YFDIDMNGHANNSKYLDWMYDVLGYEFLLHHRPCHLTLTYIKEVRPSTQITSGYHLEH
                     LTSYHEIRSSGQLNAQAIIKWQPITTKESETN"
     gene            complement(5236..6366)
                     /locus_tag="TV191_000071"
     CDS             complement(5236..6366)
                     /locus_tag="TV191_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEL1506628.1"
                     /translation="MSKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDAYLEALIKE
                     FESYQISSLKTLYIGGGTPTAITANQLDYLLSHLQQHLQLDQLEEFTIEANPGDLTED
                     KIAVLRQSAVNRISLGVQTFNDKQLKQIGRSHTEAQIYTTIASLKEAGFQNMSIDLIY
                     ALPGQTMQQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLHLPTEDLEAEM
                     FEYIISEMEASGFEHYEISNFTKPGFESRHNLMYWNNDEYFGCGAGASGYLDGIRYRN
                     RVPIQHYLKAVADGNARLSEEVLTKEEMMEEELFLGLRKKSGVSVSRFQEKFGLSFES
                     RYGPVVRELQNQGLLVEDKDFIRMTKKGLFLGDSVAEKFILD"
     gene            complement(6433..7119)
                     /locus_tag="TV191_000072"
     CDS             complement(6433..7119)
                     /locus_tag="TV191_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1506629.1"
                     /translation="MLSSSIRIGGNMIKHRVDRIASQLDELTQKLYLTMIPEYQEGYA
                     NYIYQTDQPDVQRRRIKHINKTFHRLLSESSFYLMPMTQHSAEIIAHDWIYSPAYECY
                     SMTADPEDYQSILSPKARGEHYFQVLRNGVLFGFASFFEQESELEIGLGMAPDTTGQE
                     DGVSFLGSIEAFASTTYPQETYVLNVASFNKGAQSLYQKMGYQPTSSFEQYANGSSHS
                     FVRMEKKKQP"
     gene            complement(7153..8505)
                     /locus_tag="TV191_000073"
     CDS             complement(7153..8505)
                     /locus_tag="TV191_000073"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEL1506630.1"
                     /translation="MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPRV
                     FVARDTRISGEMLEAALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASH
                     NPALDNGIKFFGSDGFKLADEQELEIEALLDAKEDLLPRPSAEGLGALVDYPEGLRKY
                     ERFLVTTGADLDGLKIALDTANGAASVSARNVFLDLNADITVIGENPNGLNINDGIGS
                     THPEKLQDLVTETASDIGLAFDGDSDRLIAVDENGAIVDGDKIMFIIGKYLSEKGLLA
                     KNTIVTTVMSNLGFHKALDSCGIHKKVTAVGDRYVVEEMRQFGYNLGGEQSGHVIIMD
                     YNTTGDGQLTAVQLTKIMKETGKTLSELASEVTIYPQKLVNIRVDNSMKERAMEVPAI
                     AEVIAQMEGEMAGNGRILVRPSGTEPLLRVMAEAPSNEEVDYYVDTIAAVVRAEIGLD
                     "
     gene            complement(8558..9514)
                     /locus_tag="TV191_000074"
     CDS             complement(8558..9514)
                     /locus_tag="TV191_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEL1506631.1"
                     /translation="MKRFLNSRLGLGLVSIFFAIILFLTAASSSHNHSNSQIYSPIET
                     YTHSLKDVPIDIKYDSDQYFISGYSYGAEVYLTSTNRIKLDSEVNSDTRSFKIVADLT
                     KSKPGTATVTLKVINLPTGVTATVSPDKISVTIGNKKTKTFPVRGSVDSKQLAKGYEI
                     SKIETGIDKVEVTSDESTIALIDHVVAKLPDDQVLDANYSSRVTLQAVAADGTILASA
                     IDPAKANLSVSVKKITKSVPIRVEAVGLMDDSLSDIQYKLSKQTAVISGSREVLETID
                     EVVAEVNISDVTKNTSKTVSLVSNQVSIEPSVVTVQLTTIKK"
     gene            complement(9511..10362)
                     /locus_tag="TV191_000075"
     CDS             complement(9511..10362)
                     /locus_tag="TV191_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEL1506632.1"
                     /translation="MSNLSSIDTKFLLSLIDDPLMLVVHLLDILIVAYLIYRFIKSLA
                     GTKIMSLVQGVIFFIIIRVIAEWIGFTTITYLMNQVITYGVIAGVVIFAPEIRAGLEK
                     FGRSTQVFLQKQSLSDEEMLVDALLKSVAYMGPRKIGALIAIEQTQTLQEYIATGIPL
                     NADISSQLLINIFIPNTPLHDGAVIVANNKIAAACAYLPLSESMSISKEFGTRHRAAI
                     GLSENSDAVTIIVSEETGAVSIARKGQFLHDLSTEELEAVLKTHLMNEPGATLPWYKK
                     ILGGKAK"
     gene            10464..11807
                     /locus_tag="TV191_000076"
     CDS             10464..11807
                     /locus_tag="TV191_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEL1506633.1"
                     /translation="MKLKTLLAIAAGRTAQLILNKIGRGSTYPGRLALMWDKDILDTL
                     AKDYEIVVVTGTNGKTLTTALTVGILKEAFGEVLTNPSGANMMTGITSAFLSAKRKKT
                     GKPIAVLEIDEASLARVTTYIKPSLFVYTNIFRDQMDRYGEIYTTYQMIVDGASQAPK
                     ATILANGDSPIFASKDLVNPVKYYGFDTPKHEPRLAHYNTEGILCPKCEQILRYRLNT
                     YANLGDYTCLNCDFQRPKLDYKLTQLTSITHHSSAFVIDDQTYRINVGGLYNIYNALA
                     AVAVAEFFGISADQIKAGFNKSKAVFGRQETFSINGKACTLVLIKNPVGASQALEMLR
                     LADYPFSLSVLLNADYADGIDTSWIWDADFELINQMDITEINAGGVRHSEIARRLRVT
                     GFDEAKITSFDKLEGIMQAIENQEAEHAYILATYTAMLAFRELLASRHIVEKEMI"
     gene            11807..12595
                     /locus_tag="TV191_000077"
     CDS             11807..12595
                     /locus_tag="TV191_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEL1506634.1"
                     /translation="MTYTSLQSPENRDYQYDLHIAHLYGNLMNTYGDNGNVLMLKYVA
                     EKLGAKVRVDIVSIGDTFDQDDYDIVFFGGGQDYEQAIVARDLPSKKEALAAYIHQNK
                     VLLAICGGFQLLGQYYIQANGLKINGIGVMGHYTLNQDNNRFIGGIKIHNDDFDETYY
                     GFENHQGRTFLSDDEKPLGRVIYGNGNNKEDQTEGVHYKNVYGSYFHGPILSRNVSLA
                     YRLVTTALKEKYGSTVSLAAYDKILQHETSEEYADVKSKASFDS"
     gene            complement(13219..14208)
                     /locus_tag="TV191_000078"
     CDS             complement(13219..14208)
                     /locus_tag="TV191_000078"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEL1506635.1"
                     /translation="MKYIVNKSHNPAFNIALEAYAFRELVDEDELFILWINEPAIIIG
                     KHQNTIQEINKEYIEQHGIHVVRRLSGGGAVYHDLNNLNYTIISNKTTEGAFDFKTFS
                     QPVIETLADLGVKANFTGRNDIEIDGKKICGNAQAYYKGRMMHHGCLLFDVDMTVLGD
                     ALKVSKDKIESKGVKSVRARVTNILNELPEKISVEAFSDKILVKMKETYPDMTEYVLS
                     EDELAKIQQSAEEQFGSWDWTYGKAPEYTIERNVRYPAGKISTFANVENSVIKNLKIY
                     GDFFGIKDVQDIESLLIGCKYEYADVLERLQTIDTTQYFSRMTVEEVAKAIVA"
     gene            complement(14450..16219)
                     /gene="lpdA"
                     /locus_tag="TV191_000079"
     CDS             complement(14450..16219)
                     /gene="lpdA"
                     /locus_tag="TV191_000079"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEL1506636.1"
                     /translation="MAVEIIMPKLGVDMQEGEIIEWKKQEGDTVSEGDILLEIMSDKT
                     NMELEAEDSGVLLKIIRQAGETVPVTEVIGYIGAAGEAIDVSSPAAADVNVARTTEDL
                     QAAGLEVPKAPDQGSAPSAPKAELAADEYDIIVVGGGPAGYYAAIRGAQLGGKIAIVE
                     KSEFGGTCLNVGCIPTKTYLKNAEILDGIKIAAGRGINLASTNYTIDMDKTVDFKNTV
                     VKTLTGGVQGLLKANKVTIFNGLGQVNPDKTVTIGVQTIKGRNIILATGSKVSRINIP
                     GIDSKLVLTSDDILDLREMPKSLAVMGGGVVGIELGLVWASYGVEVTVIEMADRIIPA
                     MDKEVSLELQKILSKKGMTIKTSVGVSEIVEANNQLTLKLNNGEEVVAEKALLSIGRV
                     PQMNGLENLNLEMDRNRIKVNDYQETSIPGIYAPGDVNGTKMLAHAAYRMGEVAAENA
                     MHGSTTRKANLKYTPAAVYTHPEVAMVGLTEEQAREQYGDVLIGKNSFTGNGRAIASN
                     EAHGFVKVIADAKYHEILGVHIIGPAAAEMINEAATIMEAELTVDELLLSIHGHPTFS
                     EVMYEAFADVLGEAIHNPPKRKK"
     gene            complement(16428..17837)
                     /locus_tag="TV191_000080"
     CDS             complement(16428..17837)
                     /locus_tag="TV191_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEL1506637.1"
                     /translation="MAVEIIMPKLGVDMQEGEIIEWKKQEGDTVSEGDILLEIMSDKT
                     NMELEAEDSGVLLKITRQAGETVPVTEVIGYIGAAGESVDNSTASSEKTTEIPVPTSA
                     EANTTTVPKEAASTAPQVASVANAPAFGEKVRATPAARKAASEMGIELNQVPGTGPKG
                     RIHKEDVEGFKGAQPKATPLARKIAADKGVDLAAVVGTGIGGKITKEDILAVLGAAAP
                     AVEKASIAEEKPAKELPEGVEIKKMSAMRKAISKGMTHSYLTAPTFTLNYDIDMTEMI
                     ALRKKLIDPIMAKTGLKVSFTDLIGLAVVKTLMKPEHEYMNASLINDANDIELHRFVN
                     LGIAVGLDDGLVVPVVHGADKMSLSEFVLASKDVIKKAQGGKLKATEMSGSTFSITNL
                     GMFGTKTFNPIINQPNSAILGIGATIPTPTVVDGEIVARPIMAMCLTIDHRLVDGMNG
                     AKFMVDLKKLMENPFELLI"
     gene            complement(17961..18959)
                     /locus_tag="TV191_000081"
     CDS             complement(17961..18959)
                     /locus_tag="TV191_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEL1506638.1"
                     /translation="MTETKLMALREAINLAMTEEMRKDDTIYLMGEDVGVYGGDFGTS
                     VGMIEEFGAKRVKDTPISEAAIAGAAIGSAITGLRPIVDLTFMDFITIALDAIVNNGA
                     KNNYMFGGGLITPATFRVASGSGIGSAAQHSQSLEAWLTHIPGIKVVAPGTANEAKGL
                     LKSAIRDNNIVIFMEPKALYGKKEEVNQDPDFYIPLGKGDIKREGTDVTIVSYGRMLE
                     RVLQAAEELAADGINVEVVDPRTLIPLDKELIINSVKKTGKLMLVNDAYKTGGFIGEI
                     AAMVTESEAFDYLDHPIVRLASEDVPVPYARVLEQAILPDVAKIKAAIVKMVNKGN"
     gene            complement(19039..20007)
                     /locus_tag="TV191_000082"
     CDS             complement(19039..20007)
                     /locus_tag="TV191_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEL1506639.1"
                     /translation="MVTVSKEQHLDMFLKMERIREFDSRINKLVRRGFVQGMTHFSVG
                     EEAANVGAVAHLTYDDIIFSNHRGHGQSIAKDMDLNKMMAELAGKVTGVSKGRGGSMH
                     LADFEKGNYGTNGIVGGGYALAVGAALTQQYKGTNNIVVAFSGDGATNEGSFHESVNM
                     AATWKLPVIFFIINNRYGISMSINNATNTPHLYTRAEAYGIPGFYCEDGNDVMAVYET
                     MSKAVEHVRGGNGPAVVEVESYRWFGHSTADAGKYRTKEEVDEWKEKDPMLKYRAYLT
                     GEGIATDEELDALQAQVKQEIDDAYEFAQNSPDPDISVAFEDVWVD"
     gene            complement(20513..22423)
                     /locus_tag="TV191_000083"
     CDS             complement(20513..22423)
                     /locus_tag="TV191_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEL1506640.1"
                     /translation="MIILQGNNIERSFSGEVLFQNLSLQVGERDRIALVGPNGAGKST
                     LLKILVGEEEPTSGEVSRKRDLTLSYLAQNSRFESDKTIYQEMLKVFAELRVDEQRLR
                     QMEADMASRSGQALDQLMSDYDRLSESFRLRNGFTYESDIRAILNGFKFDESMWEMKI
                     SELSGGQNTRLALAKMLLEKPELLVLDEPTNHLDIETIAWLEHYLVNYQGALIIVSHD
                     RYFLDKVATITLDLTKNSLDRYVGNYSRFIDLKAEKLAAEEKHYDKQQKEIAKLEDFV
                     QKNIVRASTTKRAQARRKQLEKLERLDKPSSSRKSASMTFQIDKPSGNVVLQVTDAAI
                     GYNDHILAEPIHLDVRRLDAIAIVGPNGIGKSTLLKSIIGEIPLIKGTCHYGTNVETG
                     YYDQTQSHLTGSNSVLEELWRDFPTTAELEIRSRLGAFLFSGEDVKKSVAMLSGGEKA
                     RLLLTKLSMKKDNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     KVLEITEAGSTLYLGDYDYYVEKKAEREELARLAAADHVVETDVAEAAVTDYQLQKAS
                     QKEYRRLTRRFEEIEQTLEGLEAQAKAIEAQMLVSNDTTQLIDWQKELDQLNQKQETL
                     LLEWEDIAGQLE"
     gene            complement(22833..23618)
                     /locus_tag="TV191_000084"
     CDS             complement(22833..23618)
                     /locus_tag="TV191_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEL1506641.1"
                     /translation="MASISIEYHSEILAMERHVKVIYPDQSELSPEEQGYQDIPVLYL
                     LHGMGGNENSWQKRTNIERLLRHTNLIVVMPSTDLGWYTDTTYGMNYYQAIAEELPRL
                     LASFFPNMTTKREKTFVAGLSMGGYGAFKWALKSNRFSYAASFSGALHFSPEMLLQQG
                     IGELPYWQGVFGDLNAPDIKKHYLTSIAAESDGQTQLYAWCGYEDFLFEANEKAVAEL
                     RRLGLTIDYRKDHGRHEWYYWNQQLEALLDWLPIAYHKEERLS"
     gene            complement(23724..25385)
                     /locus_tag="TV191_000085"
     CDS             complement(23724..25385)
                     /locus_tag="TV191_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEL1506642.1"
                     /translation="MTDINIIALGGVREYGKNFYLVEINDSMFILDAGLKYPETEQLG
                     VDLVIPSLDYVIENKDKVQGVFLSHGHADAIGALPYLLAEVPVPVFGSELTIELAKLF
                     VKANNSTKRFKNFHVVDSDTEIEFKDGLVSFFKTTHSIPESLGVVIGTDKGNIVYTGD
                     FKFDQASREGYQTDLARLADIGKEGVLALLADSANATSNEQTASEAEVGEEMDKVIAH
                     ADGRIIIAAVASNLVRIQQVFDSAAAYSRRVVLTGTDAENIVRTALRLKKLVIADEKL
                     LIKPKDMSKFEDHELIVLEAGRMGEPINSLQKMAIGRHRHVQIKDGDLVYIVTTPSAA
                     KEAMVARVENLIYKAGGSVKLITQHLRVSGHANARDLQLMINLVKPKYLFPIQGEYRD
                     LAAHAHLAEEAGILPENIHIMKRGDIMVLDEDGFLHEGAVPASDVMIDGNAIGDVGNI
                     VLRDRKVLSEDGIFIVAITVSKKEKRIISKAKVNTRGFVYVKKSRDILRESAELVNTT
                     VGNYLQGDHFDWSELKGSVREELSRFLFEQTKRRPAILPVVMEVR"
     gene            complement(25595..26353)
                     /locus_tag="TV191_000086"
     CDS             complement(25595..26353)
                     /locus_tag="TV191_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1506643.1"
                     /translation="MRKIIELIHATVEVNNGFDETKAILDDVSLTIYEHDFLTILGGN
                     GAGKSTLFNVIAGTLLLSKGQIKLLGHDVTHLPAEKRASYLSRVFQDPKMGTAPRMTV
                     AENLLIARQRGERRGLSSRRISHYMADFADLVKRVGNGLENHLETPTGLLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSQALMALTDDFVAKDRLTALMITHHMEDALNY
                     GNRLIVMKNGKIIQDLDQKRKSQMTIADYYQLFD"
     gene            complement(26350..27219)
                     /locus_tag="TV191_000087"
     CDS             complement(26350..27219)
                     /locus_tag="TV191_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1506644.1"
                     /translation="MIISSVSQGLLWGILGLGIYLTFRILNFPDMTTEGSFPLGGAVA
                     VTLLNLGLNPILATLAAMLAGALAGFATGLLYTKGKIPTLLAGILVMTSCHSIMLMVM
                     GRANLGLHDIKRIQDYLPFAADTNVLVAGLVVATLVIFLLMYFLYTNIGQAYIATGDN
                     RDMAKSFGIHTDRMELMGLAISNALIALSGALVSQQDGYADVSKGIGVIVIGLASIIV
                     GEVLYSTGLTLLERLIAIVVGSILYQFLISVVIALGFNTNYLKLFSAIILALCLMVPV
                     LKKAIIKEASLSR"
     gene            complement(27233..28228)
                     /locus_tag="TV191_000088"
     CDS             complement(27233..28228)
                     /locus_tag="TV191_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL1506645.1"
                     /translation="MKHKGLIVTVIALFLMVAASLVLKEGKKQPQLASKRVVKVGILQ
                     LVTHEALDQIAQGIKDELKKHHQPEQKVSITLMNAEGDQSKIQTMSKQLVKTNDIVVG
                     IATPAAQGLAAATKTIPVVMSAISDPVGAKLVKHLDRPEANVTGLSNKVPVRQTVDLI
                     KEMTPQVKRVGVLYASSEDNSISQVKDFTALAEKQGLEVLAYAVPSTNEVTTTMSVMT
                     EKVDAVFIPQDNTIASAFSAVIVASNAAQLPVYSSVDTMVEQGSLASISQSQYQLGVE
                     TARQVLQLMAGKEVSEVPVEVVDDGKPFLNLKAARDLGLMISKDLLKRSDLTGKQ"
     gene            28580..30250
                     /locus_tag="TV191_000089"
     CDS             28580..30250
                     /locus_tag="TV191_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NFACT family protein"
                     /protein_id="HEL1506646.1"
                     /translation="MSFDGFFLHHLTQELNHSIVNGRIQKVNQPFDNELVLTIRNHRQ
                     TYKLLLSAHPVFGRIQLTQTDFQNPQFPNTFTMIMRKYLQGAIIEGFEQIDNDRIIEM
                     TVSNKNEIGDAIKTTLIIEIMGKHSNIILVDRHENKIIESIKHVGFSQNSYRTILPGS
                     AYIEPPKTTAVNPFTISDIALFEVLQTQELSAKNLQKHFQGLGRDTAQELSSLLTTDK
                     LKRFRDFFQRPSQPSLTQTSFAPVAFSNTLKTFQNLSQLLDYYYHDKAERDRINQQAS
                     DLIHRVQNELEKNRSKLIKQEAELLATENAEDFRQKGELLTTYLSLVPNDQDSVELDN
                     YYTGQKITIALDKALTPNQNAQRYFKKYQKLKEAVKHLSGLIADTQQTIAYFESVDYN
                     LSQATIDEIEDIREELIQAGFVKSRKHNKHHKRKKPEQYLASDGKTIIMVGRNNLQNE
                     ELTFKMAKKGELWFHAKDIPGSHVIIKDNLSPSDEVKTDAAELAAYYSKARLSNLVQV
                     DMIEAKKLHKPSGAKPGFVTYTGQKTLRVTPIESKIQAMKCSPSASSS"
     gene            complement(30339..31577)
                     /locus_tag="TV191_000090"
     CDS             complement(30339..31577)
                     /locus_tag="TV191_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEL1506647.1"
                     /translation="MLNSEKMIASLEQQDLEQAESYFQRALQEDDAETLLALAEYLES
                     IGFLLHAKTIYLQVCEAYPEVNINLAQIAAEDNVIEEAFMYLDRIPEDSADYLSALLV
                     MADLYDLEGLTDVAREKLLQAAELSQEPIVIFGLAEIEMSLEHFSEAIEQYARLDNRH
                     ILELTGISTYQRIGRAYAYLGKFEAAVEFLEKALAIEYDDETVFELATILYDQAAYQK
                     ANLYFKQLETMNADFLGYEYPYAMSLREEHRTEEALRLVQQGLRKNAFDPQLLLLASQ
                     LAFELHDPAGSERYLLRAKEVAVDDEEVIMRLSSLYLDMERFEEVIALEHEEIDHVLT
                     KWNLAKAYQALEQQEKALTIYKDIEGDLKENPDFLQDYAYLLREFGYTDQAVKQAKRY
                     LQQVPDDIHMQGFLDDLRDD"
     gene            complement(31567..32748)
                     /locus_tag="TV191_000091"
     CDS             complement(31567..32748)
                     /locus_tag="TV191_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEL1506648.1"
                     /translation="MSLHSKPNHHDSLFYKWFLNNQAVMVLLITLLVFLTIFVFTKIS
                     FLFTPILSFLAIIMLPLVISTILYYLTKPLVDMVEKLGPNRTASIFIVFGLVILLFFW
                     AISGFIPMIQDQLRSFVEDLPKYVAKVNLEANKLLENEWLVSYRSNLQDMLTSMSQKA
                     LDYAQSFSKNAIDWAGNFAGAIARITVAIIMSPFILFYFLRDSGHMKNGLVNVLPIKL
                     RQPMARVLGEINKQLSGYVQGQVTVAIVVGLMFSVMFSLVGLNYSITFGIIAGFLNMI
                     PYLGSFLAMIPVVIMGMVQGPLMLIKVLIIFVIEQTIEGRFVAPLVLGNKLSIHPITI
                     MFLLLTAGSMFGVWGVFLVIPVYASVKVVVKELFDWYKDITGLYEEEPTEAERVAEDV
                     K"
     gene            complement(32811..33287)
                     /locus_tag="TV191_000092"
     CDS             complement(32811..33287)
                     /locus_tag="TV191_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017285310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEL1506649.1"
                     /translation="MTKLATICYIDNGEALLLLHRNKKENDVHQGKWISVGGKLEPGE
                     SPDDCARREILEETHLLVKAMDFKGVITFPDFTPGHDWYTYVFKVTDFEGDLIADEES
                     REGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFRYDDHNKLVEKTVTFY"
     gene            complement(33465..34511)
                     /gene="rfbB"
                     /locus_tag="TV191_000093"
     CDS             complement(33465..34511)
                     /gene="rfbB"
                     /locus_tag="TV191_000093"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003002700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEL1506650.1"
                     /translation="MSEYKNIIVTGGAGFIGSNFVHYVYNHHPEVHVTVLDKLTYAGN
                     RANLEEILGDRVELVVGDIADAELVDKLAAKADAIVHYAAESHNDNSLNDPSPFIYTN
                     FVGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTADTNYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSTGVWAILTKGRIGETYLIGADGEKNNKEVLELILDKMGQPKD
                     AYDHVTDRAGHDLRYAIDSTKLRQELGWEPQFTDFSEGLEQTIQWYTDHQDWWRSEKE
                     AVEANYAKTQEVIR"
     gene            complement(34703..35299)
                     /locus_tag="TV191_000094"
     CDS             complement(34703..35299)
                     /locus_tag="TV191_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HEL1506651.1"
                     /translation="MTEQFFDKALACREIEAIPGLLEFDIPVRGDNRGWFKENFQKEK
                     MIPLGFPEQFFAAGKLQNNISFSRKHVLRGLHAEPWDKYISVADEGKVLGAWVDLREG
                     DSFGHTYQTVIDASKGIFVPRGVANGFQVLTDKVAYTYLVNDYWALELKQKYAFVNYA
                     DPSLGIAWESLEQAEVSEADKSHPFLEAVKPLRQEDLS"
     gene            complement(35299..36168)
                     /gene="rfbA"
                     /locus_tag="TV191_000095"
     CDS             complement(35299..36168)
                     /gene="rfbA"
                     /locus_tag="TV191_000095"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEL1506652.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPIYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLPRFEELLGDGSEFGISLSYKEQPSPDGLAQAFIIGEEFIGDDRV
                     ALILGDNIYHGNGLTKMLQKAAAKEKGATVFGYQVKDPERFGVVEFDDEMNAISIEEK
                     PAVPKSHFAVTGLYFYDNDVVEIAKSIKPSARGELEITDVNKAYLERGDLSVELMGRG
                     FAWLDTGTHESLLEAAQYIETVQRLQNAQVANLEEIAYRMGYITKEDVYQLAQSLKKN
                     EYGQYLLRLIGEA"
     gene            complement(36225..37334)
                     /locus_tag="TV191_000096"
     CDS             complement(36225..37334)
                     /locus_tag="TV191_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEL1506653.1"
                     /translation="MTTIAIIGAGIVGSSAAYYLKKQGYQQVTIFDDGNGQATKAAAG
                     IICPWFSKRRNKAWYQLARLGADCYQDLIKELQKEGLSTHFYKQTGVYLLKKNEDKLE
                     ELYQLAIRRKQESPLIGDLAIRCRSDIRVDFPDLQGFEQLVWASGAARVDGADLCQCL
                     LEASGYQVVKKRVGISIEKQGYLVDGMVFDRLILAAGAWLPELLEPLGYQVDIRPQKG
                     QLIDYHIANVTTDNYAVVMPEGELDIIPFEHDRLSVGASHENDKGYDLEPDVAVLEAL
                     EQEALTYYPKLSSASDVSYRVGIRAYTRDFSPFFGQVPQLPGVYAASGLGSSGLTLGP
                     LIAQQLIALLLGQKASLDTSQYPIHHYIRRINDKK"
     gene            complement(37389..38177)
                     /locus_tag="TV191_000097"
     CDS             complement(37389..38177)
                     /locus_tag="TV191_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019781659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEL1506654.1"
                     /translation="MKARTIIEKYESYCPLELSMSGDVCGLQIGSLDKEVKRVMITLD
                     VRENTVAEAIAAKVDLIITKHAPIFKGLKDLVSSPQRDIVLELVKHDISVYVSHTNID
                     IVSDGLNDWFCELLGIEQTEVLVETQDGYGIGRVGNVAEQSLEELGLTVKEAFGLDVV
                     RLVRYTGQNPLISRVAICGGSGDKFYQAALAKGAQVYITGDIYYHTAQEMLTEGLLAI
                     DPGHHIESLFIDKLLAKMQAWKKEEGWQVTIMASKASTNPFSHL"
     gene            complement(38167..38853)
                     /locus_tag="TV191_000098"
     CDS             complement(38167..38853)
                     /locus_tag="TV191_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEL1506655.1"
                     /translation="MESHLSKRLRHVASYVPDGAKLLDVGSDHAYLPIFLVETEHIQE
                     AIAGEVVKGPFVSALKNVSQYGLTEHIEVRLANGLAAFEARDAVDCITICGMGGRLIA
                     DILAAGKEKLQGIERLILQPNNREDELRAWLSANAFCISAETIMTENGKYYEIIVAEP
                     GQQSLTDQEQRFGPFLSQERSSVFVAKWQKERDKLVYALSCVPATKPVERASISQKIK
                     AIEEVISHES"
     gene            complement(38927..39589)
                     /gene="nth"
                     /locus_tag="TV191_000099"
     CDS             complement(38927..39589)
                     /gene="nth"
                     /locus_tag="TV191_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEL1506656.1"
                     /translation="MRIGRERLKKVLSIIGEMFPEAKGELNWDQEKPFQLLITVILSA
                     QTTDKAVNKVTPKLWQSYPELSDLAQANVSDVEDHLRTIGLYKNKAKNIIKTAQQLLT
                     QFDGQVPKTHKELESLPGVGRKTANVVLAEIYGVPAIAVDTHVSRIAKRLNISAPDAD
                     VTEIEADLMAKLPKKDWIITHHRLIFFGRYHCLAKHPKCDTCPVQSYCSYYKTTYGKK
                     KV"
     gene            complement(39589..40266)
                     /locus_tag="TV191_000100"
     CDS             complement(39589..40266)
                     /locus_tag="TV191_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEL1506657.1"
                     /translation="MSFLEHYQSGNLVLPTALLFHYKDIFKSSDDFLVWQFFYLQNTT
                     RLDELAPSQIANALGKSVAEVNKAISSLTSQGLLDMKTIELAGEIEIIFDASPVLVTL
                     DQLLARDEKGEHEQQNTNQLKLLVDEFERELGRFLSPMELEDLEKTIHDDQTDLDLVR
                     EALREAVFNGKTNWKYIQAILRNWRKEGITSLRQLEEKKRAREDMTASEVTVSDDFLA
                     AMNLWSN"
     gene            complement(40333..40851)
                     /locus_tag="TV191_000101"
     CDS             complement(40333..40851)
                     /locus_tag="TV191_000101"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEL1506658.1"
                     /translation="MDLTQYIASIENYPKEGITFRDISPLMASGKAYSYAIREIVQYA
                     CDKDIDMIVGPEARGFIIGCPVAVELGIGFAPVRKPGKLPREVISASYEKEYGLDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIDLVEKLGGIVAGCAFLIELDGLNGRQAIG
                     DYDCKVLMHFPG"
     gene            complement(40931..41299)
                     /locus_tag="TV191_000102"
     CDS             complement(40931..41299)
                     /locus_tag="TV191_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1506659.1"
                     /translation="MRLWHQDLITRLPRQQLLGQHRECAALRGAGWGRPHATVDYVFA
                     HSLYKLYQYHLLIMQEMQARGYQPDVSWQDKNYRGKSLAAYEDLEEVALTSPIYPEHQ
                     EAYLQECLTNLKEKGIDLDD"
     gene            complement(41308..43518)
                     /gene="recJ"
                     /locus_tag="TV191_000103"
     CDS             complement(41308..43518)
                     /gene="recJ"
                     /locus_tag="TV191_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEL1506660.1"
                     /translation="MITSKYQWTIADKEPDAGFFKLAQAKGLSQTAAKLIYDRGVHTE
                     EELTSFLTADLSQLHDPYLLNDMEKAVHRIRQAIEGLERILVYGDYDADGMTAASIVK
                     ETLEMMGAEPLVYLPNRFTDGYGPNQSVYKYFIEQEQVSLIITVDNGVSGHEAVAFAQ
                     AQGVDVIVTDHHSLPAELPDAFAIIHPEHPAAAYPFQKLAGCGVAFKLASALLETIPV
                     DFLDLVAIGTIADMVSLRGENRILVKNGLAVLKETERLGLQELMKLSEVDLAHFDEDV
                     ISFKLAPQLNALGRLDDPNPAIDLLTGFDDEELHELALMISSKNEERKVLVQEIFAQA
                     MAMLDLDKPVQVLAKSGWHPGVLGIVAGRIMEEIGQTVLVLTIDEGLAKGSARSLESI
                     NIFEALNSNRSLFTAFGGHEGAAGMTLPSDRLEELSELLCQYVAAKGHDGQEKNTLLI
                     NGELDLEALSIDSLNKLLLLAPFGMDNKKPVFYLKDFTIKQARTIGQQQSHLKFKVSK
                     GAVEADVLAFGQGHLIQEYQQSQGLELAVSLAINHWRGHTSLQLMLVDARVTGVQLFD
                     IRARTARAPEHIPTAVEDQQAKVVVIDEVPDDIDALKGLFRHREFEAIYFKNHIKRPY
                     YLTGYGSREQFAKLYKTIYQYPEFDLRHKLTLLSDYLKIEKILLVKMIQIFEELGFVV
                     IEDGLMRVKTDAPKRSIADSVIYQQLKELVKFQELMALGSPQEIYQYLMTSEEK"
     gene            complement(43515..44279)
                     /locus_tag="TV191_000104"
     CDS             complement(43515..44279)
                     /locus_tag="TV191_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEL1506661.1"
                     /translation="MAQRIILITGASGGLAQAIIRQLPREDYLILLGRSKDRLDSLYQ
                     ARGNKECYEIAIQDPAAIEALVDELYQRHGRIDVLINNAGFGAFKAFDDFSAEEIEAM
                     FRVNSLASIHFARLLGHKMAEQGSGHIMNIVSMAGLIASAKSSIYSATKFAVIGFSNA
                     LRLELAERQVYVTTVNPGPIATSFFEQADPSGQYLASVAGFTLQADTVAKKIIAAIGK
                     KKREINLPISLALAHKCYTLFPTISDYLARKVFNYK"
     gene            complement(44279..45208)
                     /locus_tag="TV191_000105"
     CDS             complement(44279..45208)
                     /locus_tag="TV191_000105"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEL1506662.1"
                     /translation="MELQFLGTGAGQPAKHRNVSSLVLKLLDEINEVWMFDCGEGTQR
                     QILETTIKPRKIKKIFITHLHGDHIFGLPGFLSSRAFQASEEQTDLEIYGPVGIKSYV
                     TNSIRISGSKLPYQIHYHEFDDTSMGKILETDKFIVYAERLAHTIFCMGYRVVQKDLE
                     GTLDAEALRAVGVPFGPLFGKVKNGQDIELEDGTKIFAKDFISEPRKGKIITIIGDTR
                     KTSASVRLAKDADVLVHESTYGKGDERMARNHGHSTNMQAAQIARDAGAKRLLLNHVS
                     ARFLGRDCRQMEKDAATIFENVKVVRDLEEVII"
     gene            complement(45223..45861)
                     /locus_tag="TV191_000106"
     CDS             complement(45223..45861)
                     /locus_tag="TV191_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEL1506663.1"
                     /translation="MTDYIQLAKTYGGFTSLDTVYLQNCLKGLTDQQKLATITPPPSV
                     INAYFAEMYQKQSPKAATDYYFELSRALKLFTSEPSFDEVKPFVRLNLLGQSYGFVFE
                     NEAQEAIVFAEKEQGQPEESLLLELAQIFPQYVVYVEDGRIKMKSCQFEQGEPEDITP
                     EHALLTTIYRFSNEMTLLKGFNSDELLALSQAFKGKKYYQFAQREFMIYLVH"
     gene            complement(45854..47092)
                     /gene="hflX"
                     /locus_tag="TV191_000107"
     CDS             complement(45854..47092)
                     /gene="hflX"
                     /locus_tag="TV191_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002888940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEL1506664.1"
                     /translation="MIETKARQERVILLSVVLQAADHAELSMTELASLAKTAGAEVVD
                     CYLQKRERYDSKTFVGSGKLAEIKEMVAANEIDTVIVNNRLTARQNANLEDALGIKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYMLPRLVGQGVMLSRQAGGIGSRGPGESQ
                     LELNRRSIRHQIADIERQLAAVEKNRQTIRDRRMTSDVFNIGLIGYTNAGKSTIMTIL
                     TGDKQYEADELFATLDATTKQIYLQNQFQATLTDTVGFIQDLPTELVAAFKSTLEESR
                     HVDLLLHVIDASDPNHLEHERVVLDILKDLDMLDIPRLAIYNKMDKTASLTATVFPNV
                     RLSARDKNSRSLLRQLLIDQIRDMFEPFSIKLCQDQAYKCYDLNRLALLEPYSFDKEI
                     EEISGYIAPKNKWRLEEFYD"
     gene            complement(47177..48067)
                     /gene="miaA"
                     /locus_tag="TV191_000108"
     CDS             complement(47177..48067)
                     /gene="miaA"
                     /locus_tag="TV191_000108"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEL1506665.1"
                     /translation="MTKEKIIVIVGPTAVGKTALGIALAGAFNGEIISGDSQQVYRHL
                     DIGTAKASAREQALAVHHLIDIREVTESYSAFDFVQDAKRAIEDIVSRGKLPIIVGGT
                     GLYLQSLLEGYHLGGDLDQKELLAYRQQLETLTDTELYQLLASKGIHLDQVNRRRAIR
                     SLELNQFARDLENQEAPYNPLIIGLTDEREVIYERINKRVDLMMASGLLEEARWLFEQ
                     YPAVQASRGIGYKELFPYFQGQASLEEATATLKQQTRRFAKRQLTWFRNRMAVRFDSI
                     SESSYPQAIYDRVERFLKEP"
     gene            48200..48376
                     /locus_tag="TV191_000109"
     CDS             48200..48376
                     /locus_tag="TV191_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEL1506666.1"
                     /translation="MAKKHGFAKGLATGVLATAATVAGAVFAVKKTIIDPEEEKAAFV
                     EENRKKAARRRVAR"
     gene            complement(48532..49169)
                     /locus_tag="TV191_000110"
                     /pseudo
     CDS             complement(48532..49169)
                     /locus_tag="TV191_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677749.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
     gene            complement(49326..51590)
                     /gene="glgP"
                     /locus_tag="TV191_000111"
     CDS             complement(49326..51590)
                     /gene="glgP"
                     /locus_tag="TV191_000111"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEL1506667.1"
                     /translation="MKRFTDYTEMTLGKSLASASNEEIYLSLLSYLKEEASKKAKNTA
                     KRKVYYISAEFLIGKLLSNNLINLGIYKDIKEELAAAGKSIAEVEDVELEPSLGNGGL
                     GRLASCFIDSISSLGINGEGVGLNYHCGLFKQVFRHNEQTAEPNFWIEDDSWLVPTDI
                     SYDVPFKNFTLKSRLDRIDVLGYKRDTKNYLNLFDIEGVDYGLIKDGISFDKTDIAKN
                     LTLFLYPDDSDKNGELLRIYQQYFMVSNAAQLLIDEALERGSNLHDLADYAYVQINDT
                     HPSMVIPELIRLLTQKHGFDFDEAVSVVQKMVGYTNHTILAEALEKWPLDFLNEVVPQ
                     LVTIIEQLDALVRARVSDPAVQIIDETGRVHMAHMDIHFATSVNGVAALHTEILKNSE
                     LKAFYELYPEKFNNKTNGITFRRWLEFANQELADYIKELIGDAYLTDATRLEKLMAFA
                     EDQAVHARLAEIKHHNKVALKRYLKDNKGIELDEHSIIDTQIKRFHEYKRQQMNALYV
                     IHKYLEIKKGNLPKRKITVIFGGKAAPAYIIAQDIIHLILCLSELINNDPEVSPYLNV
                     HLVENYNVTVAEHLIPATDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIA
                     ELAGMDNIYTFGKDSDTIIDLYATGGYVSKDYYDAHPAIKEAVNFIISPELLELGNEE
                     RLDRLYKELISKDWFMTLIDLEEYIAVKEQMLADYDNQDLWLTKVVHNIAKAGFFSSD
                     RTIEQYNQDIWHSY"
     gene            complement(51616..53118)
                     /gene="malQ"
                     /locus_tag="TV191_000112"
     CDS             complement(51616..53118)
                     /gene="malQ"
                     /locus_tag="TV191_000112"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEL1506668.1"
                     /translation="MTKRASGILMHISSLPGRFGIGSFGKEAFEFVDFLKETKQTYWQ
                     ILPLTTTSFGDSPYQSFSAIAGNTHFIDLELLAKDGYLQEADYAAVDFGSNPESVDYA
                     QVFQARRPLLEKAVQAFVSTEEGLRQLAEFEATASWLNDFAEFMAIKEHFDHKALQEW
                     DDRAIVKREEAALLHYRKLLAKGITYHKVCQYFFYQQWLALKTYANQNGITIIGDMPI
                     YVSADSVEVWTMPELFKVDADKKPIYIAGVPADGFSEDGQLWGNPIYNWESHEQTGFA
                     WWIHRIKESFKLYDKLRIDHFKGFSDFWEIPGGDVTAKNGHWESAPGIALFKAVREAL
                     GELPIIAENLGYIDEKAEQLLASTGFPGMKILEFGLFDVTSQSFDLPHNYDHNCIVYT
                     GTHDNEVVNGWYEHLSAEQVEFVNHYIHKAAAESITKAMLRTIFATVCDTAILCMQDL
                     LDKSADSRMNMPNTVGGNWQWRMLEDDIKAEHKAYLIHLTELYGRANNHH"
     gene            complement(53325..54347)
                     /locus_tag="TV191_000113"
     CDS             complement(53325..54347)
                     /locus_tag="TV191_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1506669.1"
                     /translation="MVTIKDVALKAGVNPSTVSRVLKDNRSISQKTKEKVRRAMSELG
                     YVPNVAAQMLASGLTHNIGLVFPPIITNDRLSDPFFMEILSTITNEAKKHHFTVSIAT
                     GMSVEDLLSQVKLMHLQKRVDGFIILYSEQEDPVRGYLMTNQIPFVIVGAPEGDENKI
                     TYIDNDNQLMAKTAVDHLYQKGHRQILFITDDMEAEVASERYIGYLKGCLKLSLENKP
                     MLLFDRKDPISIEKVIETIRSFKATALIVIGDVLSVRMVQLLSFYDIKVPDDISIITF
                     NNSSYSKLIHPYLTTFDINVENLGRTSFRQLLDIINANEQTLSQKILVPFSLKKRESV
                     RDINAK"
     gene            54594..55847
                     /locus_tag="TV191_000114"
     CDS             54594..55847
                     /locus_tag="TV191_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL1506670.1"
                     /translation="MKSWQKVIVSGASLTLASALLVGCASGSKDKTETASGTDSKTIK
                     LWVPTGAKKSYTDVVAKFEKDSGYKVKVIESEDPKAQEKIKKDASTAADVFSLPHDQL
                     GQLVESGIIQEVPEEYTKEIADTATDQAILGAQYKGKTYAFPFGIESQVLFYNKTKLA
                     ADDVASYDTITSKATFGGTFKQANAYATGPLFMSVGNTLFGESGEDTKGTNWGNEKGV
                     AVLKWISDQASNKGFVNLDANNVMSQFGDGSVASFESGPWDYEAAQKAIGKENLGVAV
                     YPKVTIGGETVQQKAFLGVKLYAVNQAPAKGDTKRIAASYKLASYLTNAESQENQFKT
                     RNIVPANKTVQASEAVQSNELAKTVITMGSSSDYTVVMPKLSQMGTFWTESAAILSDA
                     FNGKIKEGDYLAKLQQFDKDIAATK"
     gene            56147..57508
                     /locus_tag="TV191_000115"
     CDS             56147..57508
                     /locus_tag="TV191_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1506671.1"
                     /translation="MTQAGLASQVTVKEALTKGSFDIKLSAIIMGFANFANKQFVKGT
                     LFLLSEVVFFIAFVSQIIPAIGGLITLGTQTQGMTTKTIDGISIQVAVDGDNSMLMLI
                     FGLASLIFCLLFAYIYWCNLKSARHLYMLKQEGAKIPSFKEDFVSLANGRFHMTLMTI
                     PLIGVLLFTVLPLIYMICLAFTNFDHNHLPPKSLFDWVGLSNFGNVLSGRMAGTFFPV
                     FSWTLIWAVFATVTNFFFGIILALLINTKGLKLKKMWRTFFVITIAVPQFISLLIMRN
                     LLNDQGPLNALLSKLGLIHHSLPFLSDPIWAKFSIIFVNMWIGIPFTMLIATGIIMNL
                     PSEQIEAAEIDGASKFQVFKSITFPQILIIMTPNLIQQFIGNINNFNVIYLLTGGGPT
                     NSAYYQAGTTDLLVTWLYKLTVTAADYNLASVIGILIFTVSAIFSLLAYTRTASYKEG
                     AAK"
     gene            57508..58344
                     /locus_tag="TV191_000116"
     CDS             57508..58344
                     /locus_tag="TV191_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1506672.1"
                     /translation="MKNKRRFQLGLVYAILTVLSIIWLLPIAWVVLTSFRAEGTAYVD
                     YFLPKHLTLDHYIKLFTNETFPFGRWFVNTFVVAIFTCIISTFITVAMAYSLSRIKFK
                     FRNRFLKLALVLNMFPGFMSMIAIYYILKALGLTQSLTALVLVYSAGAALGFYIAKGF
                     FDTIPYSLDESAMIDGATRMDIFFKITLPLSKPIIVYTALLAFMGPWVDFIFAQVILG
                     DATSRYTVAIGLFSMLQPDTINDWFMAFTAGSVLIAIPITLLFMFMQKYYVEGVTGGS
                     VK"
BASE COUNT        16947 a        13765 c        10960 g        16713 t
ORIGIN      
        1 gaaaaacaaa attcactcac tcaatttcaa gaactaaatt catccgaact caatcaaata
       61 acaggtggag attggtggtc agagatatta aattttaatc gctctcaaaa atataaacat
      121 acctccgtgg gttctaataa tattattgtc taacatatac ttagtattgt aataatagtt
      181 tttttagtag aaatcataac cacccgtcca acaggtggtt tgaataggga ctataaaccc
      241 atataactag ccagcgccta aagacgctgg ctttcacttt gttcaaacca cattgctatt
      301 gactcgtcac ttgcctctca aagaagtatt tgtatcactt acccttatct ctaaagggat
      361 cctcatattc ttttacactc agtttatcta gtgctatgtc atgtttttct tgttcttgaa
      421 tatatttttt tattgtagct tcatttaatc caaccgtact aatataatag ccttctgccc
      481 aaaagtgtcg attaccaaat ttgtatttca gattggcgtg cttgtcgaac atcataagcg
      541 tactcttacc ttttaaatat cctataaaac ttgaaacact tattctgggt ggaatgctta
      601 ctaacacgtg tacgtgatct ggcatcagat gtccttctat atatttctac acctttatag
      661 ctacataatc tttgaaaaat ttctcccaaa ctgcctcgat attgattata gattactttt
      721 cgtctatact taggggtgaa cacaatgtga tatttacaat gctactttgt gtgcgataaa
      781 ctgtggggct tttgtgccat atttttactc ctttcgcttt acaattggct tgaacaccta
      841 tattgtagcg cgtttggagt ttttttgtag tataacgttc gatgcgtacc cgcatagcgg
      901 gggatttttg tttcgcacct acggagcgaa acggactaaa gtcactaagt cataaccacg
      961 cgtaaaaacg ggtggcttgt acaccggcta taagccgttt ctctccagcg acgtctaaag
     1021 acgttcgctg aacttcgttc aggttagtgc tatgattact tgactaatgc ccgtaaaaac
     1081 gggcttttat cttgttttaa aactgccatc tgaaaatgga tcttcatatt ctttaacact
     1141 caacttatca agtgcaatgt catttttctc ctgctcgcga atatatttcg ctaccgtcct
     1201 tttgttcagt ccaacggtac taacatagta gcctctagcc caaaactttc gatttccata
     1261 cttatatttt aaattagcgt gtttatcaaa tatcatgaga gcacttttac ttttcaaata
     1321 ccccatgaaa tcggaaatcg aaagttttgg aggtagcaag acgagcatat gaacatgatc
     1381 tggcatcata tgtccctcaa tgatttccac gcccttgtat tgacataggt gacggaaaat
     1441 atcaattaag tcctgtctaa ttttgtagta aatggatttt ctgcggtact ttggtgtgaa
     1501 aactatgtga tatttgcaca tccatttggt atgtgataaa ctgtaactgg ttttagccat
     1561 ctctttttcc tccttgatct aacctgaaca attagattat aacaggaaaa agaaatggaa
     1621 gctcaaagcc ttgtcagcca ccagcatagc tggtggtttt cttgtttttc tctacgagaa
     1681 aaactggctc gaagccataa taaaaataaa aaccctgcca aaaaatcttt ggtagggttt
     1741 ttagcaggaa accaaatcaa tttatcagtt tctctaaatc gctctaagca atcattaaac
     1801 cttgatttac taggcttccg caatcaaatt gcgatactct attatttaag agtgatagtt
     1861 gctccagctt cttcaagctt agctttgatt tcttctgctt ctgctgctgc aacaccttct
     1921 ttgatgttag caggtgcgcc gtcaacaaga cctttagctt ctttaagtcc aagacctgtg
     1981 atttcacgaa ctgccttgat aacaccaact tttttgtcac cagcagatgt caactcaacg
     2041 tcaaatgaat ccttagtagc ttcttcagca ccaccagcag cagctacagc tacaggagca
     2101 gctgcagtca caccgaattc ttcttcgata gcttttacaa gatcgttaag ctcaaggatt
     2161 gaagcttctt taatttcagc aataatgttt tcaatgttta atgccattgt catttcctcc
     2221 aaatagttat attaaataat gatttgtagc tctaggctac ctctaaaggc cttacgcagc
     2281 gccttctttg ctttctgcaa cagccttgac agcgtatgca acgttgcgga ctggagcttg
     2341 aagtacagaa agaagcatag aaagcattcc ttcgcggttt ggcaatgctg caagtgcttg
     2401 aatttcctct tttgaagaaa caacaccttc gatagcacca cctttaatct caagtgcttc
     2461 agcagtttta gcaaagtcgt tgatgacttt agctggtgcg ataacatctt catttgaaaa
     2521 tgctactgca gatggtccta cgaatatatc ttttagctcg tcaagacctg ctttttcagc
     2581 tgcacgagtc aagattgagt ttttgataac cttgaactca acgccacttt cacgaagtga
     2641 acgacgaaga acagtatctt gatcaactgt aagaccacgt gaatctacaa caacgatact
     2701 tacagctgct ttcattttct cagcgataag ctcaacttgt tcagcttttt tagcgataat
     2761 tgcttcactc attagtttta cctccgtttt tatttttggg ctaggcacaa aaaaatcgca
     2821 cctaaaccta gacacgaaag tacaaatacg ttatcttcaa taatgacgtt ttgtgcctcg
     2881 gcaggaatat tatgagcacg ctcccctgct gtcttaggtc agttttattc aaaaccatag
     2941 ttagtatagc ctttttaaat gactttgtca acctattttt tagaaaatct taaataaaaa
     3001 aggaaagctc ttggctttcc gctaaataga tctgattagt ggctcaaaag cgcctcctaa
     3061 cttaagccta atgataagca acttgtgacg attgattgct ataacttagc ccgatcaagc
     3121 tccacagtat catctcataa ataaagaaga acaaggcaaa gcaatgccca aaaaaggcct
     3181 ctggcaaaat ccaaatgaca ggatctgtca gcggatcaaa caaccagctt gaatctccta
     3241 caaagagaat ttgatgaaaa agggtaaaga actgatcaaa gccaatcatt aaagcaaagc
     3301 aagcaatcac aattggcaat aaggctgctg ctattagccc tcttcgaagc agcataaccc
     3361 ttcctttttt gatgctctga taaaaataga taatggttgg caacataagc aggctaaaga
     3421 tcagctgtgt tatatgaaac agcattttca catctgtaaa atgctttaga ccagctcttg
     3481 atgctgaaaa gctggctagc tttagctcac gaacaaaagg attggttaag taagtcagca
     3541 atatattata gttgtggaga atagactttt tgcacatcaa aactgcctgc tctagttgca
     3601 aataatcaac ctcaatcgga taaagcagcc aagataaata gatagttatc aaaactgcca
     3661 gtgctagtag ccaaagccaa ctggcaatga acttgccttt ttcaatcata atagctccca
     3721 ctcatctaag ctagccaaga catgatcagg cttaattgga aggcttggaa cctcttttgc
     3781 ctttgtaaag ccggttgtta ctagaatagt tgccatatca ttttgaattc ctgccatgat
     3841 atctgtcagg taattgtctc caaccatagc cacctcagaa cgtggtacct ttaagatctc
     3901 tagggcttta ttcatgataa tcgcatttgg ctttcctata aatactggct tcactctagt
     3961 tgctgcctca aggagcgcat ttaaagcgcc agcacctggc attagcccac gctctgttgg
     4021 aatatttaag tcaggattgg tcccaataaa caaggctcct ttttgaatgg caagtgttgc
     4081 aattgataac atttcatagg taacctcagt atctaagcca acaacaacat aggctggatt
     4141 ttctgtatcc tcggtatagc ctgcctctgc aatggcagac tttaagccag tctcgccaat
     4201 cacataggct gttttgcctc gattcatatc attcatgtaa tcaacggttg ccattgtagc
     4261 ggtgtaaatg gtttcaagac ctgtatgaac gttaaattga ttggctagca tttcctgaac
     4321 catttcaggt gttcttgtgg tgttgttggt aactaagaga taagggatac ctttttcctg
     4381 taaacgcttg ataaagcgct caccagccgg gatacgattt ttcccttgat agatggttcc
     4441 atctaaatca attaaataag ctttataggg cactaatttg tctcactttc tttagtcgtt
     4501 ataggctgcc atttgataat ggcctgcgca ttaagctggc ctgatgacct gatctcatgg
     4561 taggaggtca aatgctctag atgatagcct gaggttattt gagtgctggg cctcacctct
     4621 ttgatatagg tcaaggtaag gtggcaaggt ctgtggtgta ataaaaattc atatcccaaa
     4681 acgtcataca tccaatccaa atacttacta ttattggcat gaccattcat atcaatgtca
     4741 aaataacgaa cctgataagc ttgaaccata ggatcctgaa gctcatctat tttgatagga
     4801 cgcttgattt tcttaacaaa gtcagcctga taaggcacca ccaaatcatc tggtatcgca
     4861 gctgccttac gtgtttgagg atttagcagg gcaaaatgag ataaaatggt catgatggca
     4921 tgacctgcct gatcataaat gtgaaattgc cggtaacaaa ataatttatt gtaagaaata
     4981 gcttgcgttt caatggttac tgtttcccca aaccttggca tacgatcaat cgttacatca
     5041 taatccgtaa caacccaaat caagccatat tgctgaagta acacctcatt gcctcgtcca
     5101 atttcagctg attgtcttgc tgataccatt aagcaatgtg ctaataaaag gggcagcttg
     5161 acatcagcct taacatcaca aaaatcaaaa gacagcttaa ggctttcgct ataccttaat
     5221 cccataacac acctcctaat ctaagatgaa tttttcagcg acagaatcac ctaaaaagag
     5281 gccttttttg gtcattctga taaagtcctt gtcctctacc aaaagcccct gattctgaag
     5341 ctctctcaca acaggaccat agcgtgactc aaatgatagg ccaaattttt cttgaaaccg
     5401 actgactgat actcctgatt tttttcgcag accaagaaaa agctcctcct ccatcatctc
     5461 ctccttggtg agcacttcct cacttaacct agcatttcca tctgctactg cctttaggta
     5521 atgctgaata ggaacccggt tgcggtaacg aatcccatca agatagccag aagcccctgc
     5581 gccacagcca aaatactcat cattattcca atacatcaga ttgtgcctgc tttcaaagcc
     5641 aggcttagta aaattagaaa tttcgtaatg ctcaaagcca ctggcttcca tttcagaaat
     5701 aatatactca aacatctcag cttccaaatc ctcagtgggc aaatggagct tgccacgacg
     5761 cattttgttc ataaaaacag tgtgatgctc taggataagg ctatacaggc taaggtgagg
     5821 aatatctaaa gcaagtgcct tagccacatt ttccttgacc tgctgcatgg tctgtccagg
     5881 caaagcataa atgagatcga tagacatatt ttgaaagcct gcctccttaa gactagcaat
     5941 ggtcgtataa atctgagcct cagtatgact gcgtccaatc tgctttaatt gcttgtcatt
     6001 aaaagtttga acgcctaggg aaatccgatt gacagccgat tgccttaata ctgcaatctt
     6061 atcctcagtc aaatcacctg gattggcctc gatggtaaat tcttcaagct ggtctagctg
     6121 taggtgctgc tgcaaatggc tcagcaaata atcaagctga ttggctgtta tggctgttgg
     6181 tgttccaccg ccaatataaa gtgtcttcaa ggagctgatc tgataggatt caaattcctt
     6241 aatcagtgcc tctaggtagg catcgacagg ctgatttttg ataaatacct tagaaaaatc
     6301 acaatagtag caaatttgtg tgcaaaaagg aatatgcaca taggctgagg ttggtttttt
     6361 tgacatggta atattatatc attttagctc agaaattcat gccaagtgat tagctttttg
     6421 acatgtacta acctaaggct gcttcttttt ctccattctc acaaaggaat gactactccc
     6481 attagcatac tgctcaaagc ttgaggttgg ctgatagccc attttttggt agaggctttg
     6541 tgcgccttta ttaaagctag cgacatttaa aacataggtt tcttgcggat aagtagtgct
     6601 agcaaaggct tcaatgctgc ccaaaaaaga aacaccatct tcctgaccag tagtatcagg
     6661 ggccatacca agaccaatct caagctctga ttcctgttca aaaaagctgg caaagccaaa
     6721 aagaacacca ttgcgaagca cttgaaagta atgctctcca cgcgccttgg gtgacaatat
     6781 tgactgatag tcctcaggat cagcagtcat gctatagcac tcataagctg ggctatagat
     6841 ccagtcatgc gcaatgattt cagcactatg ctgtgtcatc ggcatcaggt aaaaagaaga
     6901 ctcagacaat aagcgatgaa aggtcttgtt gatatgcttt atgcgacgcc gctgcacatc
     6961 aggctgatct gtttgataaa tgtaattagc atagccctcc tgatattctg gaatcattgt
     7021 caaatacagc ttttgggtca actcatcaag ctgactagca atcctatcca ctctatgctt
     7081 tatcatatta cctccaattc taatgctgct tgatagcata aaaagtgccg aagcaacgac
     7141 actttttcta gattaatcaa ggccaatttc cgcacgaaca accgctgcaa tggtatcaac
     7201 ataatagtca acttcttcat tgcttggtgc ctctgccatc acacgcaaca atggctctgt
     7261 gccgctaggc cttaccaaaa tgcgaccatt accagccatt tctccttcca tctgagcaat
     7321 aacctcagca atagcaggca cttccatagc acgctccttc atgctgttgt caacacgaat
     7381 attaacaagc ttttgtgggt aaatagtgac ctcactggcc aattcggaga gagttttacc
     7441 tgtctccttc atgattttgg tgagctgaac agctgtcagt tgaccatcac cagttgtatt
     7501 gtaatccatg ataatgacat gccctgattg ctcaccacca agattgtagc cgaactgacg
     7561 catctcctca acaacgtaac gatcaccaac agctgttacc ttcttatgaa tgccacagct
     7621 atctaatgcc ttgtgaaaac caaggttaga catcactgtt gtcacaatcg tatttttagc
     7681 tagcaagccc ttctcagaaa gatacttgcc tatgataaac atgatcttgt cgccatcaac
     7741 aatagcacca ttttcatcaa cagcaattaa acgatcacta tcgccatcaa aagccaatcc
     7801 aatatcagag gctgtttctg tcaccaagtc ctgaagcttt tcagggtgtg tagagccgat
     7861 accatcatta atgtttaatc catttggatt ctcaccaata actgtaatgt ctgcatttaa
     7921 atctaaaaag acattacgag ctgaaacaga agctgcaccg ttagcagtat caagagctat
     7981 ctttaaaccg tctaaatctg ctccagtagt aaccaagaat ctctcgtact tgcgcaagcc
     8041 ttctggataa tcaaccaagg ctcctaagcc ctccgcactt ggacgtggta ggaggtcctc
     8101 tttggcatct aagagcgctt cgatttctag ctcttgctca tcagccaatt taaagccatc
     8161 actcccaaaa aacttaatgc cattgtcaag agcaggattg tgactagctg aaatcatgac
     8221 accagcacta gccttttctg tacggaccaa ataggacaca ccaggagttg caagaacacc
     8281 aagcttatag acctctatcc caacagaaag caagccagca atcagggctg cctctagcat
     8341 ttcaccagag atacgggtgt cacgagcgac aaaaactcta ggcctttcag tctcatgctg
     8401 acttagcaca taaccaccga accgaccaag cttaaaagca agctctgggg tcaactctac
     8461 attagcctcg cctcgaacac catccgttcc aaaatatttt cccataattt atatcagcta
     8521 aacgcttcct ccattccatt ttcctagcta ttatgcttta ttttttaatt gttgtcaact
     8581 gaacggttac taccgaaggc tctatagaaa cctgatttga aaccaagctg accgttttgc
     8641 tcgtgttttt ggtgacgtca gaaatattga cctctgccac cacctcatca atagtttcaa
     8701 ggacctcccg actaccagaa ataacagcgg tctgcttgga gagcttatac tggatatctg
     8761 acagactgtc atccattagt ccaactgcct cgactcgaat aggaactgat ttggtgattt
     8821 ttttgacaga aactgacaaa ttagccttgg ctggatcgat cgcactagct aaaatggtac
     8881 catcggcagc tactgcctgc agggttactc ggctgctata attagcatct agcacctgat
     8941 catcaggtaa tttagcgaca acatgatcta tcaaggcaat agtagactca tcacttgtga
     9001 cctcaacctt gtcaatacct gtttcaattt tgctaatctc atagccctta gccagctgct
     9061 tactatcgac gctgccacgc accggaaagg tctttgtttt cttatttcca atcgttaccg
     9121 aaatcttatc aggagaaaca gttgctgtca caccagtagg tagattgata acctttaggg
     9181 tcaccgttgc agtacctggc ttactctttg ttagatcagc tacgatctta aagcttctag
     9241 tgtcactgtt tacctctgaa tccagcttta tgcggttggt agaggtcaga taaacctctg
     9301 caccgtaaga atagccgctg atgaagtact gatcactatc atacttgata tcaataggaa
     9361 cgtcctttaa gctatgggtg taggtttcaa tagggctata aatttgagaa ttagaatgat
     9421 tatgactgct agaagcagcg gtcaaaaaaa gaataatcgc aaaaaagatt gacactaagc
     9481 ccagcccaag acgactattt aaaaacctct tcatttagct ttgcctccta agattttttt
     9541 ataccaaggt aatgtcgcac cgggctcatt catcaaatga gtcttgagaa ccgcctcaag
     9601 ctcttctgtt gaaaggtcgt gtaaaaattg acccttacga gcgatagaga cagctcctgt
     9661 ctcctcagaa acaattatcg ttacagcatc agaattttct gaaagtccaa ttgctgctct
     9721 gtgacgtgtt ccaaattctt tggaaatcga cattgattca gacaagggga gataagcaca
     9781 ggctgcagca attttattgt tagccacaat gaccgcacca tcatgcagcg gtgtgtttgg
     9841 gataaagata ttgatcaata gctgactaga aatatcagca tttaggggaa ttcctgttgc
     9901 gatatattcc tgcaaggtct gcgtttgctc aatagcaatc agagcaccaa tcttccgcgg
     9961 tcccatataa gcaactgatt ttaagagcgc atcaaccagc atctcctcat cactcaagct
    10021 ttgcttttgc aaaaatacct gtgttgatcg gccaaatttt tcaagccccg ctcgaatttc
    10081 cggagcaaaa atcaccacac ctgcaatcac tccataggtg atgacctgat tcatcagata
    10141 ggttatagtc gtaaacccta tccactcggc aatcacacga atgatgataa agaatataac
    10201 cccttgtacc aaggacatga tcttagttcc tgccaaggat ttaataaaac ggtaaatcaa
    10261 ataggctact attaaaatat ccagcaaatg aaccaccaac atcaaggggt catcaatcag
    10321 gcttagtaaa aattttgtgt caatacttga taaattactc atacaattct catttctatg
    10381 tcagatagat acctctaaca ttatatcacg tttcaagatg ttttccctat ctaaaattta
    10441 agaacttatg ttaaaatatt aacatgaaac taaagacact actcgctata gcagccggaa
    10501 ggactgcgca gctcatttta aataaaatcg gaagaggctc aacctacccc ggacgattgg
    10561 ccttgatgtg ggataaggat attttagaca cacttgccaa ggactatgag attgttgttg
    10621 tgacagggac aaatgggaaa accttaacca cagctctaac tgttggtatc ctaaaagaag
    10681 cctttggtga ggttttgact aatccaagtg gcgccaacat gatgacaggg attacctctg
    10741 cctttttatc tgctaaaaga aaaaaaacag gcaagcctat tgccgtctta gagattgatg
    10801 aggcaagcct tgcaagggta acaacataca ttaagccaag tctttttgtt tacactaata
    10861 tctttcgaga ccagatggat cgctacggtg agatttacac cacctatcag atgattgttg
    10921 atggtgctag tcaagcgccg aaggcaacca ttctagctaa cggtgatagc cctatctttg
    10981 cctcaaagga cctggttaat cctgttaaat attatggctt tgacacacct aagcatgagc
    11041 cacgcctagc tcactacaac actgaaggca ttttgtgccc aaaatgtgaa cagattctcc
    11101 gttatcgtct caacacctat gctaatctag gagactatac ctgcttaaat tgtgatttcc
    11161 aaaggcctaa gttggattac aagctaacgc aattaaccag cattacccat catagctcag
    11221 cctttgtgat tgacgatcag acttatcgca taaatgttgg aggactctat aacatctata
    11281 atgccctcgc agctgttgct gttgctgagt tttttggcat ttctgctgat cagattaagg
    11341 ctggcttcaa taaaagcaag gctgtttttg gtcgtcagga aaccttctcc atcaacggta
    11401 aagcctgtac gctggttctc attaaaaacc ctgtgggtgc tagtcaggca ctagaaatgc
    11461 tgcgcctagc cgattatccc tttagcctat ctgtgctttt aaatgctgat tatgctgacg
    11521 gtattgacac aagctggatt tgggatgctg attttgaatt gattaatcaa atggacatta
    11581 ctgagatcaa cgccggtggg gttcggcatt ctgaaattgc aagacgctta cgagtgacag
    11641 gctttgatga ggctaaaatc acatcattcg ataagcttga aggtatcatg caagccattg
    11701 aaaaccaaga ggctgagcat gcctatatcc tagcgaccta tactgctatg ctagcatttc
    11761 gtgagctgct tgccagccgc cacattgtcg aaaaggagat gatctaatga cctatacctc
    11821 gctacaatct ccggaaaatc gcgattatca atacgacctt catattgctc acctttatgg
    11881 taatttgatg aatacctatg gcgataacgg caatgtcttg atgttgaagt atgtcgctga
    11941 aaagctaggc gctaaggtta gagttgatat tgtatccatt ggggatacct ttgaccaaga
    12001 tgattatgac attgttttct ttggtggtgg tcaagattat gagcaagcca ttgttgctag
    12061 agatttgcca tcaaaaaaag aggccttagc agcctatatt caccaaaata aggtactcct
    12121 tgccatttgt ggtggctttc agctgctggg acagtactat attcaagcca atggccttaa
    12181 aatcaatggc attggggtta tgggacatta taccttaaac caagataata accgctttat
    12241 cggaggcatt aaaattcaca atgatgactt tgacgaaacc tactatggct ttgaaaatca
    12301 tcaaggacgg acctttttat ctgacgatga aaagcctctt ggacgtgtca tttatggaaa
    12361 tggtaataat aaagaggacc aaactgaggg cgtccactat aaaaacgttt acggcagcta
    12421 ctttcatgga ccaatccttt cgcgtaatgt cagcctggcc tatcgcctag tcacaactgc
    12481 tctcaaagaa aaatatggct cgactgtttc cttagcggcc tatgataaga tcttacagca
    12541 tgagacctca gaggaatacg ctgatgttaa aagcaaggct agctttgaca gttaagtcct
    12601 tctcatagcc tgattaaacc acaacagaca tgcaaaacag ttattcccga atgaaaatat
    12661 agatttaaat agacaccctc aatgtttttc ctatcataaa atccataaaa gataagacat
    12721 attcttgcaa taactgaaca ttgaaagaca gaaagctttc tgtccttact aaacatcttt
    12781 catgcgtctg tcgtgctgat caagcgagat aaccccaaaa aagtgctagc acagtaacaa
    12841 aatggctatg accatatgtc tgtgcagctc tactgtcact gcatagacag gctagagggg
    12901 acgccctact tggttcagcg atctaggggt aggtctagct tgtttgtgct gagtctgttt
    12961 cggtagcaaa gattgaatcc tgctataaga tactctcaaa aagattaacc caaaagcctt
    13021 gcaacacatt taacgttttt agggataagt accgatatgc agacacatag caggagatct
    13081 atgtgtctgg taccaaagga cacaaaaaac taaagtaaca cactaaaagc cacatgatac
    13141 ccatttgata gggggcgtca tgtggctttt ttctatctca ctgttcatta caaaaagcca
    13201 aaccagcttc tttttgcatt aggcaacaat ggcctttgcc acctcttcta ctgtcatacg
    13261 tgagaaatat tgtgttgtat caatggtttg aagacgctca agcacatcag catactcgta
    13321 tttgcaacca atgagtaggc tttcaatatc ctgcacgtcc ttaataccaa agaaatcacc
    13381 gtagatctta agattcttaa taacagaatt ttcaacatta gcaaaggttg agattttacc
    13441 ggcagggtag cgaacattac gttcaatcgt gtattcaggt gcctttccat aggtccaatc
    13501 ccagctccca aattgctcct cagccgattg ttgaatctta gccagctcgt cctctgacaa
    13561 gacgtattct gtcatgtctg gataggtctc cttcatttta accaaaatct tgtctgaaaa
    13621 tgcttctacg ctgatttttt ctggcagctc atttaaaata ttggtcacgc gggctcgtac
    13681 agatttgact cctttggact caatcttatc cttactgacc ttgagcgcat caccaagaac
    13741 agtcatatcc acatcaaaca agagacagcc atgatgcatc atacgtccct tataataggc
    13801 ttgagcattg ccacagattt tcttgccatc aatttcaatg tcattgcgac ctgtaaaatt
    13861 agccttaact cctaaatcag ccaaggtctc aataactggc tgtgagaagg ttttaaaatc
    13921 aaaggctcct tctgttgttt tattggaaat aatcgtgtag ttaaggttat tgagatcatg
    13981 gtaaactgca ccaccgccag acaagcgacg aaccacatga ataccatgct gttcgatgta
    14041 ctccttgttg atttcctgaa tggtattttg atgcttacca ataataatag ccggctcatt
    14101 gatccagagg ataaacaatt catcctcatc aaccaattct ctaaaggcat aagcctctag
    14161 agcaatgtta aaggcagggt tgtggctctt attaacaatg tatttcattt ctatctccta
    14221 tagcgataat cgttatcata ttctattctt tattctaatg gaaactctta caaaagacaa
    14281 gctaaaagag gctagcaaaa gcaagggaac tagtaaatgc ttcctcaatc aagaaccatc
    14341 tgcaagctag cagtaaagct tgatctaact taaagagcct tccttgtatc aacgaaagag
    14401 ctgagaaatc tttttcccag ccctttttta tcgcagctat atagctagct tattttttac
    14461 gttttggtgg gttatgaatg gcttcgccaa gcacatctgc aaaggcttcg tacatcacct
    14521 ctgagaaggt tgggtgtcca tgaattgaca atagcaattc atcaactgtt agctcagcct
    14581 ccatgattgt ggctgcttca ttgatcattt cagcggctgc tggaccaatg atgtgaacac
    14641 caagtatttc atggtattta gcatctgcaa taacctttac aaagccatga gcctcgtttg
    14701 acgcaatagc acgaccattt cctgtaaagc tatttttacc aataagaaca tcgccatatt
    14761 gctcacgagc ctgctcttca gttaaaccaa ccatagcgac ctcagggtga gtatagaccg
    14821 ccgctggagt gtattttagg ttagccttac gtgttgtgct gccatgcatg gcattctcag
    14881 cagccacctc acccatacgg taagcagcgt gggcaagcat tttagtgccg ttaacatcac
    14941 ccggtgcata aatgcctggg attgacgttt cttggtagtc attaacctta atgcggttac
    15001 ggtccatttc aaggttgagg ttttcaagac cattcatctg tggcacacgt ccaatagata
    15061 gcaaggcctt ttcagcaaca acctcttcgc cattattaag cttcaaggtc aactggttgt
    15121 tggcttcaac aatctcagag acaccaactg aggtctttat tgtcatgcct ttcttagaaa
    15181 ggattttttg aagctccagt gaaacctcct tgtccatggc aggaataatg cggtcagcca
    15241 tttcaataac tgtaacctct acaccgtaag aggcccaaac aagaccaagc tcaataccaa
    15301 caacaccacc gcccataaca gcaagtgatt tcggcatttc acgcaaatca agaatatcat
    15361 cagatgtcaa gacaagctta gaatcaatcc ctggaatatt gatgcgtgag accttagagc
    15421 ctgtcgcaag aataatattg cgccctttaa tggtttgcac accaatggta accgttttat
    15481 caggatttac ctgaccaagg ccattaaaga tggttacctt gttggcttta agaagccctt
    15541 gaaccccacc tgttagcgtc ttaacaaccg tatttttaaa gtcaactgtc ttatccatgt
    15601 caatagtata gttggttgaa gcaaggttaa tcccgcgtcc tgctgcaatc ttgatgccat
    15661 caaggatttc agcatttttg aggtaggttt ttgttgggat acagccaacg tttaagcagg
    15721 taccgccaaa ttcagatttt tcaacgatag caatcttgcc gcccagctga gcaccacgaa
    15781 tagcagcgta gtaacccgca ggaccgccac cgacaacaat gatgtcatat tcatcagcag
    15841 caagctctgc ctttggtgct gatggcgctg atccttgatc cggtgccttt ggcacctcaa
    15901 gaccagccgc ctgtaaatcc tcggttgtac gcgcaacatt gacatcagcc gctgctgggc
    15961 ttgatacatc gatagcttca cccgcagctc caatgtagcc gataacttcg gttacaggga
    16021 ctgtctcacc tgcctggcga atgattttta aaagcacacc tgagtcttct gcttctaatt
    16081 ccatattggt cttgtctgac atgatttcca gaagaatgtc accctcgctg acagtgtcac
    16141 cctcctgctt tttccactcg atgatctcgc cttcttgcat gtcaacaccg agctttggca
    16201 taataatttc aacagccata atgatattgt aaggaacgtt caaatgcaat cagatgcctt
    16261 aacaatcagc actggctaac ataagcctgc taaaagccct gcatttagct catagctagt
    16321 gactacgagc tcgttccaga tcctttctat agttttaaag aattatcttt tcgttacttt
    16381 gtttctgaaa tatgctctct ttgcatcgca ggccataagg cctgtcatca gattagcagt
    16441 tcaaatggat tttccatcaa ttttttgaga tcaaccatga atttagcacc attcatgccg
    16501 tccaccagac ggtggtcaat tgtcagacac attgccatga ttggacgtgc aacaatctca
    16561 ccatcgacca ctgttggggt tggaatggtt gccccaatac ctagaatagc tgaattaggc
    16621 tgattgataa ttggattgaa ggttttggtg ccaaacatac ccagatttgt gatggagaag
    16681 gttgagcctg acatttcggt agcctttagc ttgcctcctt gagccttttt gataacgtcc
    16741 ttagaagcaa ggacaaactc tgagagactc atcttatctg caccatgaac aactggcaca
    16801 actagcccat catcaagtcc tacagcaata ccaaggttga caaagcgatg aagctcaata
    16861 tcattagcat cattaatcaa tgacgcattc atgtattcgt gctctggctt catcaaggtc
    16921 ttaacaacgg ctaaaccaat caagtcagta aagctaacct ttagccctgt tttagccatg
    16981 attgggtcaa tcagcttctt gcgcaaggca atcatttcgg tcatgtcaat gtcataatta
    17041 agcgtaaagg ttggtgctgt aaggtaggaa tgtgtcatac cctttgaaat agccttacgc
    17101 atagcagaca tcttcttaat ttcaacaccc tctggaagct ccttagcagg cttttcttca
    17161 gcaatagatg ctttttccac agcaggtgct gctgcgccaa gcacagccaa aatgtcctcc
    17221 ttggtaatct tgccaccaat acctgttccg accaccgctg caaggtcaac tcccttgtcg
    17281 gcagctatct tacgagcaag tggcgttgcc ttaggctgag ctcctttgaa gccttcaacg
    17341 tcttctttgt ggatacggcc ctttggtcct gttcctggca cttggttaag ctcaattccc
    17401 atttctgaag ctgctttacg agctgctggc gttgcgcgta ccttttctcc gaaggctgga
    17461 gcattggcaa ctgatgctac ctgaggcgct gttgaggctg cttctttcgg tacagttgtt
    17521 gtattagctt ctgctgatgt tggtactgga atttcagttg ttttctcact tgaagcagta
    17581 ctattatcaa cagattcacc tgcagcacca atatagccga taacctcagt gacagggact
    17641 gtttcacctg cctggcgagt gatttttaga agcacacctg aatcctctgc ttcaagctcc
    17701 atatttgtct tgtctgacat gatttcaaga agaatgtcac cctcgctaac agtgtcaccc
    17761 tcctgctttt tccactcgat gatctcgcct tcttgcatgt caacaccgag ctttggcata
    17821 ataatttcga cagccatata tttcctttca tttaatcccg cagcccatga tcttaagacc
    17881 agatacagct gctgaaaaaa gggatactgt tttatcagcc tgatgaagaa agcctctaag
    17941 ctaagacttc ctttgccatg ctaatttccc ttgttgacca tttttacaat agcagccttg
    18001 attttagcaa catctggtaa gatagcttgc tcaagaacac gtgcataagg tactggtacg
    18061 tcctcactag caagacgcac aattgggtga tcaaggtaat caaaggcttc actttcagtg
    18121 accattgctg caatctcacc gataaagcca ccagtcttat aggcatcatt aacaagcata
    18181 agcttccctg tcttcttaac agaattaata attaattcct tatctagtgg gataagggta
    18241 cgtggatcaa caacctccac attaatacca tcagctgcaa gctcttcggc tgcctgaagg
    18301 acacgctcta gcatacgccc ataggaaaca atggttacat cagtcccttc acgcttgata
    18361 tcccccttgc caagtgggat ataaaaatct ggatcctgat tgacctcttc ttttttaccg
    18421 tacaaggcct taggctccat gaaaataaca atattgttat cacgaatagc tgactttaaa
    18481 agtccctttg cttcgttagc agttccaggt gcaaccacct tgatcccagg aatatgcgtc
    18541 aaccaagcct caagagattg cgaatgctga gctgcagatc caattcctga gccagaagca
    18601 acacgaaaag ttgctggcgt gatcaagcca ccaccaaaca tgtagttgtt ttttgcccca
    18661 ttattaacaa ttgcatcaag tgcaatggta ataaagtcca taaaagtaag gtcaacaatc
    18721 ggacgaagcc ctgtaattgc tgaaccaatc gctgcacctg caatagcagc ctctgaaatc
    18781 ggcgtatcct tgacacgttt ggcaccaaat tcctcaatca tgccaacaga agtaccaaag
    18841 tctcctccgt aaacacctac gtcctcaccc ataaggtaaa tcgtgtcatc tttgcgcatc
    18901 tcctctgtca tggcaagatt gatagcctca cgcaaagcca ttaattttgt ttctgtcatt
    18961 attatctcct aatgtttaca aaatagaatt gtcaatgtta ctgtgaatag atttttgctc
    19021 gatgtgctag cagatcagct agtctaccca aacgtcctca aaggctacag aaatgtctgg
    19081 atctggacta ttttgtgcaa actcataagc gtcatcaatt tcttgcttga cctgtgcttg
    19141 aagcgcatct aattcttcat ctgtagcaat gccttcacct gttaggtaag cgcgatactt
    19201 aagcattggg tccttttcct tccactcatc aacctcttct ttggtgcggt atttgccggc
    19261 atcagcagtt gaatgaccaa accaacggta agactcaacc tcaacaacag caggaccatt
    19321 gccaccgcga acatgctcaa cagccttact catggtttca taaactgcca tcacatcgtt
    19381 gccgtcctca caataaaagc ctggaatacc ataagcctca gcacgcgtgt agaggtgagg
    19441 tgtatttgtg gcattgttaa tgctcatgga aatcccatag cggttgttaa tgataaagaa
    19501 aatcacagga agcttccaag ttgctgccat attgacagac tcatggaagg agccctcatt
    19561 tgttgcgcca tctccagaaa aggccacaac gatattgttg gtccccttgt attgctgtgt
    19621 caaggcagca cctaccgcaa gggcatagcc acctccaacg ataccatttg ttccatagtt
    19681 tcctttttca aaatcagcca agtgcattga gccgccgcgt ccctttgaca cacctgttac
    19741 cttaccggct agctcagcca tcattttatt gaggtccata tctttagcaa tagattgccc
    19801 atgcccgcgg tggtttgaaa aaataatatc atcataggtc aaatgtgcca cagcgccaac
    19861 gtttgctgcc tcctcaccaa ctgagaagtg tgtcatgccc tgcacaaatc cacgacggac
    19921 aagcttatta atacgtgaat caaattcacg aatacgctcc attttaagga acatatctaa
    19981 atgttgttct ttagaaactg ttaccatttc ggcctccata ttatcatatt acttcctaat
    20041 cataaaactt ttcttcacaa tttgcaagga ttttaatcgc tttctttgtg actataaaag
    20101 cttttttaag acgttttagt ttgtggtttc acaagctaga ttgttatagc atctgttaca
    20161 tttatatata acagattgaa aaatgagtca gtgtttattc agggaggtca agcacctatt
    20221 gactttgata gtcagaaata tcatcactct ttaagaggaa aataggctct aaatgacctg
    20281 tttcttctag cacaatcatg atcacctacc aaacgaacgc tttgcttgcc tcgctccgat
    20341 agaggcgaaa tgaactaaaa atcgcataac taaaaatgcc tgattttacc tgaaaatcag
    20401 acatttaaaa gctttaagac attagactca ggctctaatt ataatcctct aagaaaagcc
    20461 tgctaccttg cactacccaa gaatagcaag gcaatttcat tatctcacca ggctactcca
    20521 gctgtcctgc aatgtcctcc cactccagca gcaaggtctc ctgtttctga ttaagctgat
    20581 ccaactcttt ttgccagtct atcagttgag tcgtatcatt tgatactagc atttgagctt
    20641 ctatagcctt agcctgtgct tctagccctt ctaaggtctg ctcaatctcc tcaaagcgcc
    20701 ttgttaagcg acggtattcc ttttggctgg ccttttgaag ctgataatca gttacagcag
    20761 cttctgctac atcagtctct actacgtgat ctgcagcagc tagacgggct aattcctccc
    20821 gctctgcctt tttttctaca taatagtcgt agtcccccag atagagtgtt gagcctgctt
    20881 cagttatttc taaaacctta gtggccactc ggttgataaa atacctgtca tgactaacaa
    20941 acaacaaggt cccatcaaag tcaatcaagg cattttctag aacctctttg ctatcaatat
    21001 ccaggtggtt ggttggctca tctagaatca gaaaattgtc ctttttcata gataattttg
    21061 ttaagagcag ccgagccttt tcgcccccag atagcatggc cacagacttt ttgacgtcct
    21121 caccagaaaa gagaaaggca cctaagcggc tgcggatctc aagctcagct gtcgttggga
    21181 aatcacgcca aagctcctcc aatacagaat tactaccagt cagatgagat tgcgtttggt
    21241 cataatagcc tgtttcaaca ttagtcccat aatggcatgt ccctttaatc aaaggaatct
    21301 ctccaataat ggatttgagt agggttgact tgccaatacc atttggccca acaatagcga
    21361 ttgcatctaa cctacggaca tctagatgaa ttggctcagc taaaatatgg tcattgtagc
    21421 caatagcggc gtctgtcacc tgcaaaacaa catttcctga gggcttatca atctgaaaag
    21481 tcatactagc tgatttgcga gagctacttg gcttgtctaa gcgttctagc ttttctagct
    21541 gcttgcgtct tgcctgagca cgcttggtcg ttgacgctcg aacaatgttt ttttggacaa
    21601 aatcctctag cttagcaatc tctttttgct gcttgtcata atgcttctct tctgctgcaa
    21661 gcttttcagc ctttaaatca ataaagcgtg agtaattacc aacatagcgg tctaagctat
    21721 ttttagtcag atcaagtgtg atggttgcga ccttatccaa gaaatagcgg tcatgactga
    21781 caatgatcaa ggctccctga taatttacca gataatgctc cagccaggca atggtttcaa
    21841 tatctaaatg gttggtcggc tcatcaagca ccaatagctc tggcttttct agtagcattt
    21901 ttgccagggc caaacgggta ttttgcccac cagaaagctc tgagattttc atttcccaca
    21961 tgctttcgtc aaacttaaag ccatttaaaa tagctcgaat atctgactca taggtgaagc
    22021 catttcgcaa gcgaaagctt tctgacagcc ggtcatagtc tgacatgagc tggtccagag
    22081 cttgccctga tcgactggcc atatcagcct ccatttgcct tagtcgctgc tcatcaaccc
    22141 tcaattcagc aaataccttt agcatttcct gataaatggt cttgtcagac tcaaatcggc
    22201 tattttgtgc caaataagat agggttaagt ccctttttcg actaacctca ccgctagttg
    22261 gctcttcttc tccaactaaa atcttaagaa gggttgattt gccagcacca tttggcccaa
    22321 ccaaggcaat gcgatcacgt tcaccaacct gcagcgatag gttttgaaaa agcacctctc
    22381 ctgaaaaaga gcgctcaatg ttatttcctt gtaatataat cataccctta ttgtagcaaa
    22441 aaaatgccct tttggggggc acttttagtt atttttacag gtaagataag actcatcaac
    22501 aagctaaaga cataagcctt aggctaacat cgcttatcac ccttagtggt atttatctga
    22561 tgagacaaac tgctgcttga aaaaccagtg ggttgacctg ttagcgtatc caacaatcgc
    22621 accacctgct cagttatgct tgaaatgcta ttagccagtg aggaatcact atggttcgaa
    22681 taataaatca aaccaaaaat aagcaatacc aatactatta gggtctgcaa acagcctctg
    22741 acaagctgcc agacaagctt cagcagaagc tttgggaggc ataagaggat agtcagtagt
    22801 tttttcatcg taataagcct aaattctttc gtttaggata gcctttcttc cttgtggtaa
    22861 gcaatcggca gccaatctaa tagggcctct agctgctgat tccaataata ccattcgtgc
    22921 ctgccatgat ccttacgata atcaatagtc aagccaagcc ttctcaactc agcaactgcc
    22981 ttttcattgg cttcaaacaa aaagtcctca tagccacacc aagcgtatag ctgggtttga
    23041 ccatcacttt ctgctgctat acttgtcaaa taatgctttt tgatatcagg agcattcaaa
    23101 tctccaaaaa caccctgcca ataaggcagc tcacctatac cttgctgtaa tagcatttcc
    23161 ggcgaaaaat gcaaggcccc agaaaaggaa gcagcatagg aaaagcgatt gctttttaag
    23221 gcccatttaa aggcaccata gcctcccatt gacagcccag caacaaaggt tttttcacgc
    23281 ttagtggtca tattaggaaa gaaagaagct aatagccgag gaagttcctc tgcaatagct
    23341 tggtaataat tcataccgta ggtggtatcg gtataccagc ctaaatcagt cgatggcatc
    23401 accacgatta aattggtatg gcgaagcagc ctttcaatat tagtccgctt ttgccaggaa
    23461 ttttcatttc ctcccatacc atgtaacaga taaagaactg gaatatcttg gtagccttgc
    23521 tcttctgggc taagctcaga ctgatcaggg tagatcacct tgacatgtct ttccatagcc
    23581 aagatctctg aatgatactc aatgctaatg cttgccatca gctcacctcc tttttaatat
    23641 caccaaagca taaggaaagc ccactcttaa gacctaaaag ccagatccta tttgaccagc
    23701 ttttaggcag ggctgtatct gtattaacgg acctccataa caaccggaag aatagctggc
    23761 cgacgcttgg tctgctcaaa taaaaacctt gagagctcct ctctaacaga gcctttcaat
    23821 tcactccaat caaaatgatc cccttgcaga taattgccaa ctgttgtgtt gaccaattca
    23881 gcactttctc gtaaaatatc tctgctcttt ttcacataga caaatccgcg agtgttgacc
    23941 ttagccttag agataatacg tttttccttt ttagatactg tgatcgcaac aataaaaata
    24001 ccgtcctctg ataagacctt acggtctctc aaaacaatat tgccaacatc accaatggca
    24061 tttccatcaa tcatcacatc actagcagga accgcaccct cgtgtaagaa gccatcctca
    24121 tcaagcacca tgatgtcacc acgcttcata atatgaatat tttcaggtag tataccagcc
    24181 tcctcagcta aatgagcatg agcagctaga tcgcggtatt caccttgaat cgggaacagg
    24241 tattttggtt tgacgagatt aatcatcagc tgcaggtcac gcgcattggc atgtccagaa
    24301 acacgtaaat gctgcgtgat gagcttaaca gagccacctg ctttatagat aaggttttca
    24361 acacgagcaa ccattgcttc cttggcagcg cttggcgttg tgacaatgta aaccagatct
    24421 ccgtccttga tttgcacgtg gcgatgacgc cctattgcca ttttctgtag gctattaatc
    24481 ggctcaccca tacgtccagc ctccagaaca atcaattcgt gatcctcaaa cttagacata
    24541 tcctttggct tgattaatag cttttcatca gcaatcacta gctttttaag acgaagtgct
    24601 gttctgacaa tattttcagc gtcagtacct gtcagtacca ctcgcctgct ataggctgct
    24661 gcagaatcaa agacctgctg gatacgaaca agatttgaag cgacagctgc aatgataatc
    24721 cgcccgtcgg catgagcaat caccttatcc atctcctcgc caacctcagc ttcgctggca
    24781 gtctgctcat tgcttgtggc attggccgag tcagctaata gggctaacac cccttctttt
    24841 ccaatgtctg ccaagcgagc taggtctgtc tgatagccct cacgcgaagc ctggtcaaac
    24901 ttgaaatcac ctgtatagac aatattcccc ttatcggttc caataaccac gcctaaactt
    24961 tcaggaatag aatgtgttgt cttaaagaag gaaaccaagc catctttaaa ttcaatttct
    25021 gtgtcactgt cgaccacatg gaaattctta aatctcttgg tgctattatt ggccttgaca
    25081 aacaattttg ctagctcgat ggtcaattct gaaccaaata ctggcactgg aacctccgcc
    25141 aacaggtaag gcaaagctcc gatagcatca gcatgcccat gacttaaaaa gactccctga
    25201 accttgtcct tgttttcaat tacataatca agacttggaa ttaccaaatc tacacctagc
    25261 tgttctgttt cagggtattt caagccagca tccaaaatga acatggaatc gttaatctct
    25321 actagataga agtttttccc gtactcacgt acgcctccta atgcaataat gtttatatca
    25381 gtcatgatac tccttttttt atattagtta ttacaaacgg tccttactgg gtaagtcgaa
    25441 ttactgtctt gcagctaagc tgcactcttt tacagtatat catattttag ggcttattac
    25501 ctcaaattgc cttgagactt tctcaatctt ttcaatagat tatcaaaaaa gccaagggaa
    25561 ggctttcatt ccaatggctt ttagagtatt tattttagtc aaaaagctgg taataatcag
    25621 caatggtcat ttgagatttt ctcttctgat caaggtcttg aatgatttta ccatttttca
    25681 tcacaatcag gcgattacca tagttaagag cgtcctccat gtgatgcgtt atcattaagg
    25741 ctgtcaagcg atccttagct acaaaatcat cagtcaaggc cattaaggct tggctggtct
    25801 tagggtctag cgctgcagta tgctcatcta atagtaaaag ctctggtctt tttagggttg
    25861 ccatgagtaa gctaagggcc tgtctttgac cgcctgataa gagaccagtc ggagtctcca
    25921 gatgattttc caagccattt ccaactcgct tgaccaagtc agcaaagtct gccatataat
    25981 ggctaatcct gcgtgatgac aagcctcgcc tttcccctct ttgccttgca atcaaaaggt
    26041 tttcagctac tgtcattcga ggtgctgttc ccattttagg atcctgaaaa acacgtgata
    26101 ggtagctagc tcttttttct gctggcaggt gcgtcacatc atgccctaaa agcttaattt
    26161 gacccttgct taacaatagc gtcccagcaa tcacattaaa aagggttgat ttaccagcgc
    26221 cattcccacc aagaatcgtt aaaaaatcat gctcataaat ggtcaaggaa acatcatcta
    26281 aaatagcctt agtctcatca aagccattat tgacttcgac agtagcgtga attaattcaa
    26341 taatttttct catcgtgata agctagcctc cttaataatt gcttttttta gcacaggcac
    26401 catcaggcaa agtgctaata taatggcact aaatagctta agataatttg tattaaagcc
    26461 aagagcaata actactgaga ttaaaaattg atacaggata gaaccaacca caatggctat
    26521 caagcgctca agcagggtta ggcctgtaga atataaaacc tcaccaacaa taatactcgc
    26581 aaggccaatt acaatcacac caatcccctt tgaaacatca gcatagccat cttgctgact
    26641 aaccaaggca ccagataagg ctatcaaggc attagagatc gctaagccca taagctccat
    26701 acgatcagta tgaatcccaa agctcttagc catatcccga ttatctcctg tggcaatata
    26761 agcctgacca atattggtgt aaagaaaata cattaacaaa aaaatcacca atgtagctac
    26821 aaccaaacca gctaccaaca cattggtgtc agctgcaaag ggaaggtagt cctgaatgcg
    26881 cttgatatca tgcaagccca aattggccct gcccataacc ataagcataa tggaatggca
    26941 ggaggtcatg actagtatgc cggcaagaag tgttggtatc tttccttttg tgtataacag
    27001 gcctgtggcg aagcctgcca aggcacccgc cagcatagca gccagagtag ccaggatagg
    27061 atttaaaccg agattgagca gagttactgc tacagcacct cctaaaggaa aggacccttc
    27121 tgttgtcata tctgggaaat tcaatattct aaaggtcagg taaatcccca agccaagaat
    27181 tccccataac aagccttgtg atacagatga aataatcata tgaactcctt ttctattgct
    27241 tacctgtaag gtcagaacgc ttcagcaggt cttttgagat cataagacct aaatcccttg
    27301 ctgcctttag atttaaaaat ggcttaccgt catcaactac ctcgacagga acctctgata
    27361 cctcttttcc agccataagc tgcagcacct gcctagctgt ctcaacccct aattggtatt
    27421 gactttgtga aatagaagca agactccctt gctcaaccat tgtatcaaca cttgagtaga
    27481 ccggaagctg tgctgcattt gaggcaacaa tcaccgctga aaaagcactg gcaatagtat
    27541 tatcctgtgg gataaaaaca gcatctacct tctcagtcat cacagacatg gtcgtggtaa
    27601 cctcatttgt tgaggggaca gcgtaagcta gaacctccaa gccttgcttt tctgcaagag
    27661 ctgtaaagtc cttgacctgt gatattgaat tgtcctcact gcttgcataa aggacaccga
    27721 cccttttgac ctgaggggtc atctccttga tcagatcaac cgtctgtcga acaggaacct
    27781 tatttgataa gccagtaaca tttgcctcag gcctgtctaa gtgcttgact aatttagcac
    27841 caactggatc agaaatagct gacatcacaa ccgggatagt cttggttgct gctgctaatc
    27901 cttgagctgc aggcgttgcg atgccaacaa caatatcgtt tgttttgacc agctgcttgc
    27961 tcatggtctg aatcttactt tgatctcctt ctgcattcat aagggtaatg ctgacctttt
    28021 gctctggctg atgatgcttc tttagctcgt ctttaatgcc ctgtgcaatc tggtcaagcg
    28081 cctcatgagt aaccagctgc aatataccaa ccttaaccac acgcttgctg gctaactgtg
    28141 gctgtttttt gccctctttt agcactagcg aagcagcaac cattaaaaag agtgcaatga
    28201 ctgttacgat aagaccttta tgtttcatgt tctacctctt aatttccatt cttactccgt
    28261 tgctaacatt tagagtactc acaaaaagaa aaaacgctta gtaatcagct actaggcgct
    28321 ttttttgaaa tccaatgtca gcgcatagat acctttttag aagtactcta aaagtcgtat
    28381 ctatgctaac ccataaacac aactttatct atgccagctt tgccaattta tcatatgctg
    28441 tgtttgcttc atcttggatt tcctttcttg tttttttaca ttataaccta aaagctcaaa
    28501 aatacaagag catttgaaca tatttttcca ttattttttg tggtataatg aaagaattag
    28561 aactcaggag ggagaaacca tgtcatttga cggctttttc ttacatcatt taactcaaga
    28621 gctcaaccat agtattgtta atgggcgcat tcaaaaagtc aatcaaccct ttgataatga
    28681 gttggttctg actatccgta accatcgcca aacttacaag ctcttgctct cagctcatcc
    28741 ggtttttgga cgcattcaac tgacccaaac agactttcaa aatcctcaat ttcccaatac
    28801 ctttaccatg atcatgcgca aataccttca aggagctatc attgaaggct ttgagcagat
    28861 tgataatgac cgcatcatcg aaatgaccgt ctctaacaaa aatgagattg gcgatgccat
    28921 aaagacgaca ttgatcatcg aaattatggg caagcacagc aatattattc tggttgaccg
    28981 tcatgaaaac aaaattatcg agtctatcaa gcacgtcggc ttttcccaaa attcctaccg
    29041 gactatttta ccaggatcag cctatatcga gcctccgaaa acaactgctg tcaatccttt
    29101 tacgatctca gatatcgctt tatttgaagt cctgcaaaca caggagttat ctgctaaaaa
    29161 tcttcaaaag catttccaag ggcttggccg agataccgca caagagctat ccagtctcct
    29221 gacaactgat aagctaaaac ggtttagaga cttttttcaa agacctagtc agccaagtct
    29281 aactcagacc tcctttgctc cagttgcctt ctcaaacaca ctgaagacct tccagaatct
    29341 atctcagctg ctagattatt attatcatga caaggctgag agagatcgta tcaaccagca
    29401 ggccagtgac ctgatccacc gcgttcaaaa cgaattggaa aaaaatcgca gcaaactgat
    29461 taagcaagag gctgagctgc tagccactga aaatgcggag gactttcgcc aaaagggtga
    29521 gctcttaaca acctatctga gcctggtgcc aaatgaccag gattcagttg agcttgataa
    29581 ctactatacc ggccaaaaaa taaccattgc acttgataag gcgttgactc ccaatcaaaa
    29641 tgcccaacgc tattttaaaa aatatcaaaa attaaaagaa gctgtcaagc acctctcagg
    29701 tctcatcgct gacacgcaac aaaccatcgc ttattttgaa agcgttgatt acaatctatc
    29761 tcaggcaacg attgatgaaa ttgaggacat tcgagaagag cttattcagg ctggctttgt
    29821 gaaaagccgt aagcataaca agcaccacaa acgtaaaaag ccagagcaat acctggcttc
    29881 agatggcaaa acaattatta tggtcggacg taacaatctg caaaatgagg aattaacctt
    29941 taaaatggcc aaaaaaggcg agctctggtt tcatgctaag gatattcccg gcagccatgt
    30001 gatcattaag gacaatctaa gcccaagcga cgaggtcaaa actgatgctg ctgaattggc
    30061 ggcctattat tctaaagcaa gactttccaa tctcgttcag gtggacatga ttgaagccaa
    30121 aaagctgcac aagccaagtg gtgcaaagcc tggctttgtc acctatacag gacaaaagac
    30181 actaagagtg acacctatag aaagcaagat tcaagccatg aagtgctccc cttcagcctc
    30241 ttcctcatag gactacagca ataaagataa aaaaagctac agcctcacac ttggagatag
    30301 gtccagtctt aaagctgcgg cttttttatc attacttgtt aatcatctct caaatcatct
    30361 aagaagcctt gcatatgaat atcatctgga acctgctgca aatacctttt tgcctgctta
    30421 actgcttgat cagtatagcc gaattccctt aataaataag cataatcctg taaaaagtca
    30481 ggattttctt ttaggtctcc ttcgatatct ttatagatag tgagggcttt ttcttgctgc
    30541 tccagagcct gataggcctt ggcaagattc catttagtta gcacatgatc aatctcctca
    30601 tgctcaagag caatgacctc ctcaaaacgc tccatatcca agtacaggct agataagcgc
    30661 atgatgacct cttcgtcatc aacagctact tccttggccc tgagcaaata ccgctctgag
    30721 ccagctggat catgcaattc aaaggcaagc tgtgaagcaa gcaacagcag ctgggggtca
    30781 aaggcatttt tacgcagacc ctgctgaact aggcgtaagg cctcttctgt ccgatgctcc
    30841 tcacgcaagc tcatggcata ggggtactcg tagcctaaaa agtctgcatt catcgtttct
    30901 aattgcttga aatagagatt ggccttttgg taagcagcct gatcatataa aatcgtcgcc
    30961 agctcaaaca ctgtctcatc gtcatactca atggcaagag ccttttcaag aaactctaca
    31021 gcagcttcaa atttccctaa ataagcatag gcacgcccta tgcgctggta ggttgagata
    31081 cctgtcagct caagaatgtg acgattatca agcctagcat attgctcaat agcctcgcta
    31141 aagtgctcca gagacatctc gatttcggct aagccaaaga tcactatcgg ctcctgactc
    31201 aattcagctg cttgaagtag cttctcacgc gccacatcag ttagcccctc caaatcataa
    31261 agatcagcca tgacgagcag agcagacaaa taatcagcac tatcctctgg aatcctatca
    31321 aggtacataa aggcctcttc aatgacatta tcctcagctg caatctgagc aagattaata
    31381 ttgacctccg gataagcctc acagacctgc aaataaatcg tcttagcatg cagtaaaaaa
    31441 ccaatactct ctaggtattc tgccaaagcc aacaaggtct cagcatcgtc ctcctgcaag
    31501 gctctttgaa aatagctttc tgcctgctct aaatcctgtt gctctagtga ggcaatcatt
    31561 ttttcactat ttaacatctt cagcgaccct ctcagcttct gtaggctctt cctcatacag
    31621 gcctgtaata tccttgtacc aatcaaatag ctccttcaca acaaccttaa cagaagcata
    31681 aactggaatg acaagaaaga caccccagac cccaaacatt gaccctgctg tcaataataa
    31741 aaacataatg gtaatcgggt gaatgctcag cttatttcca agcactagcg gcgcgacaaa
    31801 acgtccttca atcgtttgtt caataacaaa aataatcaac accttgatca gcatcaaggg
    31861 tccttgcacc attcccataa tcactacagg aatcatggct aaaaagctcc ccagataagg
    31921 aatcatatta agaaagcctg caataatacc aaaggtaata gaatagttca aaccaacaag
    31981 gctaaacatc actgaaaaca tgagaccaac cacaatcgca acggtcacct gtccctgcac
    32041 atagccagat aattgcttgt tgatttctcc taagacacgt gccataggct ggcgcagctt
    32101 aatcggaagc acattgacca aaccattttt catatggcca ctgtcacgca gaaaataaaa
    32161 gagaataaaa ggtgacatga tgattgcaac agtaatacgg gcaatagctc cagcaaaatt
    32221 tcctgcccaa tcaatagcat ttttagagaa gctttgcgca taatctagag ccttttggct
    32281 catactagtc agcatatcct gcaggttgga cctgtagcta accagccatt cgttttcaag
    32341 tagcttatta gcctctagat tgaccttggc aacatatttg ggaaggtctt cgacaaagct
    32401 ccttagctgg tcttgaatca tagggataaa gccagaaata gcccagaaaa ataggagaat
    32461 tactaagcca aagacaataa aaatagaggc tgtgcgattt ggacctagct tctcaaccat
    32521 atcaactaat ggcttggtca aataatacag gatagttgag ataaccagcg gcagcatgat
    32581 aatggccaaa aatgacaaga tcggtgtaaa gaggaaggat atttttgtaa agacaaaaat
    32641 agtcagaaaa accagcagcg tgattaacaa aaccatcacc gcctgattat ttaaaaacca
    32701 tttgtaaaat agactatcat gatgattagg cttagaatgc aatgacatta atggtatcgt
    32761 cctttcttaa ttgtggcatc attctgatga gagcttttag gttagttgac ttaataaaag
    32821 gtgactgttt tttccactag cttgttgtgg tcatcatacc taaatttagc agaaaaaaac
    32881 ggccggtctt ccagtatcca cttgaaaatg tcgtaatctc cctcccaggt tggcttttcc
    32941 agcacctgat catagggaac ccattctagg gtcccttctc tggactcctc atcagcaatt
    33001 aagtcacctt caaagtctgt caccttaaac acgtaagtat accaatcatg ccctggtgta
    33061 aaatcaggaa aggtaatcac tcccttaaag tccattgctt ttaccagcag gtgagtttcc
    33121 tctaaaattt cacgtctggc acagtcatca ggagattcgc ctggctctaa tttgccacca
    33181 actgaaatcc acttaccttg gtgaacatca ttttccttct tgttgcgatg cagcagcaat
    33241 aaagcctcac cgttatcaat ataacaaatc gttgctaact tagtcattca tacccttcct
    33301 ttgtttagtt gttactatta taccaatctc tgagaaatat gccatcattt tatcatttaa
    33361 gcacatcaaa caagaaaacc acaatcacta caactcttag ccctgtacta gcaaaaaagc
    33421 cttgataagg caacgtctgc tgactcatca agacttatca ctatttaacg aatcacttcc
    33481 tgtgtcttag cgtaattggc ttcaactgct tctttttcgg aacgccacca atcctgatga
    33541 tcagtatacc attggatcgt ttgctcaagt ccttctgaaa aatcagtaaa ctgtggctcc
    33601 cagccaagct cctgacgaag ctttgtcgaa tcaatagcat agcgtaaatc gtggcctgca
    33661 cgatccgtta catggtcata agcgtcctta ggctgcccca ttttatccag gattaattcc
    33721 agcacttcct tattattttt ttcgccgtca gctccaataa ggtaggtctc accaatacgt
    33781 cccttggtca aaatggccca aacaccagtt gagtggtcat tggtgtgaat ccagtcacga
    33841 acattctttc cttcaccata caattttggc ttgataccag acaagatatt agtgatctga
    33901 cgagggataa atttctcgat atgctggtag ggaccataat tatttgaaca gtttgaaatg
    33961 gttgccttca cgccaaagga gcgaacccag gccttaacaa tcaaatcaga ggctgccttg
    34021 gttgatgaat aaggtgacga cggattatag ttagtatcag cggtgaattt ttcacctggc
    34081 ccctcaccat gacctggcaa atcctcacgc agtggcagat ccccataaac ctcatcagtg
    34141 gacacatgat ggaagcgaat atcatattta cgagccgcct ctaagagtgt ataagtccca
    34201 acgaagttcg tgtaaataaa tggacttggg tcattgagtg aattatcatt gtggctttca
    34261 gcagcatagt ggacaatagc atctgcctta gcggccagct tatctaccaa ttcagcatca
    34321 gcaatgtcac caacaaccaa ctccacgcga tcacccaaaa tctcctcaag gttggcacga
    34381 ttgccagcgt aggtgagctt atccaaaaca gttacgtgaa cctctgggtg atggttgtaa
    34441 acataatgta cgaagtttga accgataaag ccagcgccac cggtaacaat aatgttttta
    34501 tattcagaca tgttttttct tttcctttgt tttcagctat cagcactcaa aatgcagctt
    34561 aatccgacag gcaagctcag ttaccagtga aaacagcgac taagctgcct cacctcattg
    34621 ctcctaccat ccataaggtc cttcctatca gaaggataca gagacactcc catcaaaagc
    34681 catagcttat ttcaaatgct aattatgata aatcttcttg tctcaaaggc ttaacggcct
    34741 ctaggaaggg atggctttta tctgcttctg aaacctctgc ttgttcaaga ctttcccacg
    34801 caatcccaag gcttgggtca gcataattaa caaaggcata tttttgcttg agctcaagcg
    34861 cccaataatc attgaccaga taggtataag ccaccttatc agtcagtact tgaaagccat
    34921 tagcaacacc tcgagggaca aaaatcccct ttgaagcgtc aatgactgtt tgataggtat
    34981 gcccaaagct atcaccctca cgaagatcaa cccaagctcc aagaacctta ccctcatcag
    35041 caacagagat gtacttgtcc caaggctctg catgcaggcc tcgaagcaca tgcttgcgcg
    35101 aaaatgaaat attgttttgc agcttacctg cggcaaaaaa ctgctcagga aagcctagag
    35161 gaatcatttt ttccttttga aaattttcct taaaccagcc acgattgtcc cctcgaacag
    35221 ggatatcaaa ctccaaaagt ccaggaatgg cttcaatttc ccgacaggct aaggctttat
    35281 caaaaaattg ttctgtcatc aagcttctcc aatcaaccgc agcaggtact gcccgtattc
    35341 gtttttctta agcgactgcg ctagctggta gacatcttct ttagtgatat aacccatgcg
    35401 ataggcaatc tcctctaggt tggccacctg agcgttttgc aagcgttgaa ctgtctcgat
    35461 gtattgggca gcctccagca ggctttcatg agtgccagta tctagccagg caaagccacg
    35521 tcccatcaac tcaaccgata ggtcgccacg ctctaaatag gctttattaa catcagtaat
    35581 ctcaagctct cctctggcac ttggtttaat gcttttagca atctcgacta catcattgtc
    35641 gtaaaaataa aggcctgtta cagcaaaatg tgacttagga actgccggct tttcttcgat
    35701 agaaatggca ttcatctcat cgtcaaactc cacaacccca aaacgctccg gatccttgac
    35761 ctgataacca aaaacagtgg ctcctttttc cttagctgct gccttttgga gcattttcgt
    35821 aaggccgttt ccatgataga tgttgtcacc taaaatcaag gcaactcgat catcaccaat
    35881 aaactcctca ccaatgataa aggcctgtgc taagccgtca ggacttggtt gctccttgta
    35941 ggacaagctt atcccaaact ctgagccatc gcctaatagc tcttcaaatc ttggaagatc
    36001 ttggggagtt gaaataatca aaatgtctcg aatccctgcc agcatcagtg ttgataaggg
    36061 ataataaatc attggcttat cataaattgg catcaattgc tttgaagctg cacgagtaag
    36121 agggtacaag cgtgttcctg atcctcctgc cagaataata cctttcatcg tagctctcct
    36181 cattttataa tacgtcacta ttttatcatt ttttaaaaac agtgtcactt tttatcatta
    36241 atccgacgaa tataatgatg aatcgggtat tgactagtat ctaagctagc tttttgcccc
    36301 aaaagcaggg caatcagctg ctgagcaatc aaaggaccta gggtcaagcc agatgagcct
    36361 agaccgcttg cggcgtaaac acctggtagc tgaggtacct gcccaaaaaa tggagaaaaa
    36421 tctctggtat aggctcgaat gcctacgcgg taagaaacat cagaggcaga actcagctta
    36481 gggtaatagg tcaaggcctc ctgctccaag gcctctaaaa cagctacatc aggctcaagg
    36541 tcatagccct tatcattttc atgactcgct cctacagaca acctatcatg ctcaaaggga
    36601 ataatatcca gctccccctc tggcatgacc actgcgtagt tatctgtagt cacattcgca
    36661 atgtgataat caatgagctg tcctttttgc ggtcgaatat ccacctgata gccaagtggc
    36721 tcaagcaatt ctggcagcca agcaccagcg gctagaatca gccgatcaaa gaccatacca
    36781 tcaacgagat agccttgctt ttctatgctt atgccaacac gctttttaac cacctgatag
    36841 ccactagctt caagcaaaca ctgacatagg tctgccccat caacacgtgc agccccagaa
    36901 gcccatacca gctgctcaaa accctgtaaa tcaggaaaat caaccctaat gtccgaacga
    36961 caccttatcg ccaaatctcc aatcaaaggc gactcttgct tgcgtctaat ggccagctgg
    37021 tagagctcct ctagcttgtc ctcattcttt tttaataaat aaacaccagt ctgcttataa
    37081 aaatgtgtag aaagcccctc tttttgcagc tccttgatta agtcctgata acaatctgct
    37141 cctaaccgag ccagctggta ccaagcctta ttccttcttt ttgaaaacca agggcagata
    37201 atgccagcgg ctgccttagt tgcttgacca ttaccatcat caaaaatagt aacctgctga
    37261 tacccttgtt tttttaaata ataagcggcg cttgaaccta caattccagc tccaatgatt
    37321 gctatcgttg tcattgccgt ttccattcta tcatactgct taccaagcat aggccatact
    37381 cagtcatgct atagatgact aaagggattt gttgacgcct tgctagccat aatggttact
    37441 tgccagcctt cctctttttt ccaagcctgc atcttggcaa gtagtttatc aataaataag
    37501 gactcgatgt gatgccctgg atcaattgcc agcaggcctt ctgtcagcat ttcctgtgct
    37561 gtgtgataat aaatgtcacc agtaatataa acttgagctc ccttagcaag cgctgcctga
    37621 taaaatttat caccactgcc cccacaaata gccactcgcg aaatcaaagg gttttgacca
    37681 gtatatcgaa ccagccgaac cacatcaagc ccaaaggctt ctttaactgt aagtcctaac
    37741 tcctccaagc tttgctctgc tacatttccg acacgtccaa taccataccc atcttgcgtc
    37801 tcaaccaata cctctgtctg ctcaatgccc aacagctcac aaaaccaatc gttgagcccg
    37861 tcagagacaa tatctatatt ggtatgactg acatagacag aaatatcgtg cttcaccagc
    37921 tcaaggacaa tatctcgctg tggcgaggag accaagtcct tcaagccctt aaaaatagga
    37981 gcgtgcttgg tgataatcag gtctaccttg gccgcaatag cttcggcaac ggtattttct
    38041 ctcacatcaa gggtgatcat tacccttttg acctccttat ccagagagcc aatttggagg
    38101 ccacacacat ctcctgacat ggatagctca agcggacaat agctttcata tttttcgatg
    38161 attgttctag ctttcatgac tgatgacctc ctcaatcgct tttatttttt gagaaatgct
    38221 agcgcgttca acaggcttcg ttgctggcac acaagacagg gcatagacaa gcttatctcg
    38281 ctctttttgc catttagcca caaagactga tgacctttcc tgagacaaga aaggaccaaa
    38341 gcgctgctcc tgatctgtta gactttgttg accaggctct gcaacaatga tttcataata
    38401 tttgccattt tctgtcatga tggtttcagc actaatacaa aaagcattgg cagatagcca
    38461 agcacgcagc tcatcctctc gattattggg ctgtaaaatc aagcgctcaa tcccttgcag
    38521 cttttcctta ccagccgcta aaatgtcagc tattaaacgc cctcccatgc cacagatggt
    38581 tatgcagtct acagcatctc tcgcctcaaa ggcagctaag ccattagcca gacgcacctc
    38641 aatatgctct gtcaaaccat attgtgacac attttttagg gctgatacaa aaggtccctt
    38701 gaccacctca cctgcaatcg cctcttgaat atgctcggtt tcaaccaaaa aaataggaag
    38761 ataagcatga tcacttccca cgtctaaaag cttagcacca tcagggacat aggatgccac
    38821 atggcgtaag cgctttgata aatgactttc cattttctta atccttctaa caactaatcg
    38881 tatcactatt atagcaaaat acagaccaat taaaaagaaa gccacatcag accttctttt
    38941 taccataggt agtcttgtaa tagctgcaat agctctgtac tgggcaggta tcacacttag
    39001 gatgcttagc caagcagtga tagcgtccaa aaaagatcaa acggtggtgg gtgatgatcc
    39061 aatccttctt aggaagcttg gccatcaaat cagcttcaat ttcagtaaca tcggcatctg
    39121 gggcagaaat gttcaagcgc ttggcaatcc ttgacacatg cgtgtcaact gcgattgcag
    39181 ggacaccata aatctctgcc aagaccacat tagcagtctt acggcctact cctggtaagg
    39241 attcgagctc cttatgggtt tttggtacct gaccatcaaa ctgtgtcagt agctgctgag
    39301 ctgtcttgat gatatttttt gccttatttt tatacaagcc aattgtcctt aggtgatcct
    39361 caacatctga cacatttgcc tgagccaaat ctgaaagctc tgggtagctt tgccacagct
    39421 taggggtaac cttgttgact gccttatcag ttgtctgcgc tgataggata accgtaataa
    39481 gaagctgaaa gggcttttct tggtcccaat tcagctcgcc cttagcctct ggaaacatct
    39541 caccaatgat tgatagaacc ttttttaatc gttctcttcc tatcctcatt agttactcca
    39601 aaggttcatc gccgcaagaa aatcatctga aaccgtcact tcagacgccg tcatatcctc
    39661 tctggcacgc tttttttcct caagctgcct gaggcttgta attccctcct tgcgccaatt
    39721 tcttagaata gcctgaatat atttccaatt ggtttttcca ttaaagacag cctctctcag
    39781 cgcctcacgc actaaatcca gatctgtttg gtcatcatga atggtttttt ccaaatcctc
    39841 tagctccatc ggactcaaaa aacgacccag ctcacgctca aactcatcaa caagaagttt
    39901 caattggttg gtgttttgct gttcatgctc acccttttca tcacgcgcca atagctggtc
    39961 taaagtgact aatacaggac tagcatcaaa aatgatctca atctctccag ccagctctat
    40021 ggttttcata tctaataacc cctgactggt caaggaagaa atagccttat tcacctctgc
    40081 tacagactta cccaaggcat tagcaatctg actaggtgcc aattcgtcaa gcctagtcgt
    40141 attttggaga tagaaaaact gccaaaccaa aaaatcgtct gagctcttaa aaatatcctt
    40201 gtaatgaaac agtaaggcag ttggaaggac caaattgcca gactgataat gctctaaaaa
    40261 actcataatt cccctgccaa acgtaatagc ccaacctagc ttttaatcag tactgccatt
    40321 agcaagcact gattaaccag gaaaatgcat caatacctta caatcgtaat caccaatagc
    40381 ctgacgacca ttcaagccgt ccagctcaat gagaaaagcg cagccagcaa caatgccgcc
    40441 cagcttttca accagatcaa tagtagcctt tactgtacca cctgttgcta ataagtcgtc
    40501 cacaataagg acacgttggc ccggcttaat agcatcagca tgcatggtca aggtgtctag
    40561 accatactcc ttttcatagc tagcagaaat cacctctctt ggcaatttac ccggcttacg
    40621 aacaggagca aagccaattc ctagctcaac tgcgaccgga cagccaataa taaagccacg
    40681 agcctccggt ccaacaatca tgtcaatgtc cttatcgcag gcatattgca caatctcacg
    40741 aatagcatag ctgtaggcct tgccactagc cattagcggc gaaatatcac gaaaggtaat
    40801 cccctccttt gggtaattct caattgaagc aatatattgt gttaaatcca tcgtaaaata
    40861 gtctttctaa tgtcttttaa attaaaatct ttcctattat agcatgaaag tctaaaaagg
    40921 taaatgattc ctaatcatcc agatcaatcc ctttttcctt taaattagtc aggcattcct
    40981 gtaaataggc ctcttgatgc tcaggataaa tcggtgaggt cagtgccacc tcctctaagt
    41041 cctcataggc ggcaaggctt tttcctcggt aatttttatc ctgccagctc acatctggct
    41101 ggtagccccg cgcctgcatt tcctgcataa tcaacaggtg atactggtaa agcttataaa
    41161 gagaatgggc aaacacatag tcaaccgtcg catgtggtct cccccagcct gctcctcgca
    41221 aggccgcaca ttcacgatgc tgccccaaca attgctgcct tggtaggcgt gtgattaaat
    41281 cctgatgcca aagacgcata agctctccta tttctcttca ctagtcatta aatactgata
    41341 aatctcctgc ggactgccca aggccataag ctcttgaaac tttaccagct cttttagctg
    41401 ttggtaaatg acactgtcag cgatgctacg ttttggggca tcagtcttta ccctcatcag
    41461 cccatcttcg attactacaa agcctaactc ctcaaaaatt tgtatcattt tgaccaagag
    41521 gattttttca atcttgaggt aatcacttag caaggtcagc ttatggcgaa gatcaaattc
    41581 tgggtattga tagatggtct tataaagctt ggcaaattgc tctctactgc catagcctgt
    41641 taggtaataa gggcgcttaa tatgattttt aaagtaaatc gcttcaaatt cccgatgtct
    41701 aaaaaggcct ttcaaggcat caatatcgtc aggaacctca tctatgacaa caaccttggc
    41761 ctgctggtcc tcaacagctg taggaatatg ctcaggtgcc ctagcagtcc ttgctcgaat
    41821 atcaaacagc tgcaccccag tcactctagc gtcaaccagc attaattgca ggctagtatg
    41881 acctcgccag tgattgatcg caagactaac cgctaattcc aagccctgtg attgctggta
    41941 ctcctgtatc agatgtccct gaccaaaggc caagacatca gcctcaacgg ctcctttgct
    42001 gaccttgaac ttcaagtgac tttgttgctg accaatggtc cttgcctgct taatcgtaaa
    42061 atcttttaag taaaaaacag gctttttatt atccatgcca aagggtgcta gaagtagcag
    42121 cttgttcaga ctatctatac tcaatgcttc taaatccaat tcaccattga tcaatagagt
    42181 gtttttttcc tgaccatcgt gtcccttggc tgccacgtat tggcaaagta gctctgatag
    42241 ctcctctagg cgatcagatg gcagagtcat gcctgctgcc ccctcatgac caccaaaggc
    42301 tgtaaataag ctcctattgc tattaagtgc ttcaaagata ttaatgctct ctaagcttct
    42361 ggctgagccc ttggctagcc cctcatcaat ggtcaaaaca agaacagtct gcccaatctc
    42421 ctccatgatc cgaccagcta caatccctaa gacccctggg tgccagccag acttagctaa
    42481 aacctgcaca ggcttgtcta gatcaagcat agccattgct tgagcaaaaa tctcctgtac
    42541 caagaccttt ctttcctcat ttttactact aatcatcaag gcaagctcat gaagctcttc
    42601 gtcatcaaag cctgtcagta gatcaatagc tggatttgga tcgtcaagac gccctagagc
    42661 attgagctgc ggagcaagct taaagctaat aacatcttca tcaaaatgcg ctaagtcaac
    42721 ctctgaaagc ttcatcagct cctgcaagcc tagtctttct gtctctttta gaacagccag
    42781 cccgtttttg acaaggatac ggttttcacc tcgtaggctg accatatcag caattgtccc
    42841 aatagcaacc agatctaaaa agtctactgg aattgtctct aacagagctg aagccaactt
    42901 gaaggcgacg ccacagccag ctagtttttg aaagggataa gcagcagctg ggtgctcagg
    42961 gtgaataata gcaaaggcat caggtagctc tgctggcagg ctgtggtggt ctgttacaat
    43021 aacatctacc ccctgtgctt gcgcaaaggc aaccgcttca tggcctgaaa caccattgtc
    43081 aacggtaata atcagcgaaa cctgctcttg ctcgatgaaa tacttgtaaa cactttgatt
    43141 gggaccatag ccatctgtaa agcgattagg caaataaaca agaggctctg ctcccatcat
    43201 ttccagcgtt tccttgacaa tagacgccgc tgtcatgcca tctgcatcat aatctccgta
    43261 gaccaaaatc ctctcaagcc cctcaatggc ctgacgaatg cgatgaacag ctttttccat
    43321 atcatttagc aaataagggt catggagctg tgataggtca gctgtcaaaa agctggtaag
    43381 ctcctcttcg gtatgaacac ctcggtcata gatgagcttt gcagctgtct gactaagtcc
    43441 ctttgcctga gctagcttaa agaagccagc atctggctcc ttatcagcta tggtccactg
    43501 atatttggac gtaatcattt ataattaaat acctttcttg caagataatc agatatagtt
    43561 ggaaacaagg tataacactt atgagcaagg gctaggctaa taggcagatt aatctctcgt
    43621 ttcttttttc ctattgcagc aatgattttt ttcgccacag tatccgcctg cagcgtaaag
    43681 cctgcaacac tggctaaata ctgcccgctt gggtcagcct gctcaaaaaa ggaggttgca
    43741 atcgggcctg gattaacagt tgtcacataa acctgccttt ctgccagctc caagcgaagg
    43801 gcattagaaa agccaatgac tgcaaacttt gtcgcagaat agatacttga cttggcagaa
    43861 gctattaagc ctgccattga gacaatattc ataatatgtc cagagccctg ctctgccatt
    43921 ttgtggccaa gcaagcgtgc aaaatgaatg ctggctaagc tattcacacg aaacatggcc
    43981 tcaatctctt ctgcagagaa atcatcaaag gccttaaaag caccaaagcc tgcattgtta
    44041 atcaaaacat caatcctgcc atggcgctgg taaagctcat caacaagagc ctcaatagca
    44101 gcagggtctt gaatagcaat ctcgtagcat tccttattac cgcgagcctg atatagactg
    44161 tctaacctgt ctttgctgcg ccctaacaaa atcaggtaat cttctcttgg aagctgtctg
    44221 atgatagcct gtgcgagccc gccagaagca cctgttatca gaataattct ctgtgccatt
    44281 aaatgatcac ttcctctaaa tcgcgaacaa ccttcacatt ttcaaaaata gttgccgcat
    44341 ccttttccat ttgacgacag tcacgtccta aaaagcgtgc tgaaacatga ttcagtaaaa
    44401 gacgcttagc acctgcatca cgcgcgattt gagcagcctg catgtttgtc gaatgcccat
    44461 gattacgggc cattctttca tcacccttcc cgtaggtgga ctcatgcacc agcacatcag
    44521 catcttttgc caatctaaca ctagcagatg tcttgcgtgt atcgccaata atggtgatga
    44581 tctttccttt tcgaggctct gaaataaagt ccttggcaaa aattttggtg ccatcctcta
    44641 gctcaatatc ctgcccattt ttaaccttgc caaaaagtgg accaaagggc actcctactg
    44701 ctctaagagc ttctgcatca agtgttcctt ctaaatcctt ttgaaccaca cgatacccca
    44761 tacaaaagat ggtatgtgcc aagcgctcag cataaacaat aaatttatct gtttctaaaa
    44821 tcttgcccat agaggtgtca tcaaactcat gataatgaat ctgataaggc aatttagagc
    44881 ctgatatcct gatgctgttt gttacatagg attttatccc aacaggtcca taaatctcaa
    44941 ggtccgtctg ctcctcacta gcttgaaaag cccgactaga taaaaagcca ggcaagccaa
    45001 aaatatgatc accatgcaga tgcgtgataa aaatcttctt gatttttcgt ggcttgattg
    45061 ttgtttctaa aatttgccgc tgggttccct cgccacaatc aaacatccac acctcattga
    45121 tttcatctaa tagctttagc actaagcttg aaacgttgcg atgcttggct ggctgcccag
    45181 ctccagtacc taaaaattgt aattccatac agtctattct ttctaatgca caaggtaaat
    45241 catgaattct ctttgtgcaa actgataata tttctttcct ttgaatgctt ggctaagagc
    45301 caacaattca tcactattaa agccctttag cagggtcatt tcgtttgaga aacgatagat
    45361 cgtggttaac aaagcatgct caggtgttat gtcctctggc tctccttgct caaattggca
    45421 gctcttcatc ttgattctac catcttccac ataaaccacg tattgtggaa aaatctgagc
    45481 cagctccagc agcagcgatt cctcaggctg cccctgctct ttttcagcaa aaacaatcgc
    45541 ctcctgtgct tcattttcaa agacaaagcc ataggattgc cccaacaaat ttaagcggac
    45601 aaagggcttc acctcatcaa atgacggctc tgaggtaaac agcttcaagg cccttgatag
    45661 ctcaaaataa taatctgtcg ctgcttttgg tgattgcttc tgatacattt ctgcaaaata
    45721 agcattaatc acacttgggg gtggcgtgat ggtagctaat ttttgctggt ctgtcaagcc
    45781 ctttaagcaa ttttgcaaat aaaccgtatc taaactcgta aagcctccat aagtctttgc
    45841 caattgaata taatcagtca taaaattctt ctaatctcca tttatttttg ggagcaatgt
    45901 agccagaaat ctcttcaatc tccttatcaa agctataagg ctccaataac gccaacctgt
    45961 tgaggtcata gcatttgtag gcttgatcct gacagagctt gatcgaaaat ggctcaaaca
    46021 tgtcccgaat ctgatcaata agcaactgtc ttaagaggct acgactgttt ttatcacgtg
    46081 ctgacagcct gacatttgga aaaacagttg cagtcaagct agctgtctta tccatcttgt
    46141 tataaatagc cagccttgga atatccagca tatctaaatc tttcaagatg tctagaacaa
    46201 ccctctcatg ctccaaatga ttagggtcac tggcatcaat cacatgcaag agcaaatcaa
    46261 catgccgact ttcctctaat gtcgacttaa aagcagccac gagctccgtt ggtaaatctt
    46321 ggataaagcc tacagtatct gtcagagttg cctgaaactg attttgcaga taaatttgct
    46381 tggtggtggc atcaagtgtt gcaaataatt catcagcctc atattgcttg tcaccagtca
    46441 aaatagtcat aatagtagac ttacctgcat tggtatagcc gatcaatcca atattaaaga
    46501 catcagaggt catgcggcga tcacgaatcg tttgacggtt tttttcgaca gcagctagct
    46561 gccgctcaat atctgcaatc tgatgacgaa tggagcgccg gttcagctcc agctggctct
    46621 cacccggccc acgactccca atgcccccgg cctgacgact aagcataaca ccctgtccga
    46681 ccagtcttgg cagcatgtat ttgagctgcg ctaaatgcac ctgcaatttc ccttcatggc
    46741 ttctagcccg catcgcaaaa atatcaagaa tcagctgcat gcgatcaatg accttaatac
    46801 ctaaggcgtc ctccaaattg gcattttgcc gagccgttaa acgattgtta acaatcactg
    46861 tatcaatctc attggcagca accatttctt tgatttcagc cagcttacca gagccaacaa
    46921 aggtcttgct atcatagcgc tccctctttt gcagatagca atcaacgacc tctgcacctg
    46981 cggtcttggc tagactagcc agctctgtca ttgatagctc agcatggtca gctgcttgta
    47041 ggaccacgct tagtaaaata actctttcct gccttgcctt tgtctctatc atgaacgcga
    47101 ctaatcctcc aaattccgta gtgtttatta tagcatagtt ttagctattt tcagctagtt
    47161 tgccatcgat agcttcctaa ggctccttca aaaagcgctc caccctatca tatattgcct
    47221 gcggatagga cgactcgcta atcgagtcaa agcgcactgc catacggtta cgaaaccaag
    47281 tcagctgtcg tttagcaaag cggcgtgttt gctgctttag tgtggctgtt gcttcttcta
    47341 aactagcctg accctgaaag taagggaaga gctccttata accgatccct cgactagcct
    47401 gaacagctgg atactgctca aaaagccacc ttgcctcctc caataggcca gaagccatca
    47461 tcagatccac ccgcttatta atccgctcat aaataacctc tcgctcatca gtcaagccaa
    47521 tgatcaaggg gttatagggg gcctcttgat tttctaaatc cctagcaaat tgatttagct
    47581 caagtgagcg aatggcacgc ctgcggttaa cctgatcaag gtgaatgccc ttactagcta
    47641 atagctgata aagctctgta tctgtcagtg tctctagctg ctgccgataa gcaagtagct
    47701 ccttttgatc aagatctcct cctagatgat agccctctaa caggctttgc aaatacaggc
    47761 cggtaccacc gacaataatc ggcagtttac cgcggctaac aatatcttca atagctcgct
    47821 tagcgtcctg cacaaaatca aaggctgagt aagactctgt cacctcacga atgtcaatca
    47881 aatgatgaac cgcaagagcc tgctccctgg cactagcctt agctgtccca atatcaaggt
    47941 gacgataaac ctgctgacta tctccagata taatttcacc attaaaggca ccagccaagg
    48001 caatccctag agctgtcttg ccaacagcag tcgggcctac aatcacaatt atcttttctt
    48061 ttgtcattta ttgtctttct acttaaaaag cagctgaaaa agtcttttac ttgaattttc
    48121 taatcttttt cgctaccata tattataaca taagattgag agacagttat ggtcctctta
    48181 atagaaatgg agaatgatta tggctaaaaa acatggattc gcaaagggtc ttgctacagg
    48241 tgttcttgct actgctgcta ccgttgcagg tgcagtattt gctgttaaaa agactattat
    48301 tgaccctgag gaagaaaaag cagcatttgt agaggaaaat cgtaaaaaag cagcacgtcg
    48361 tcgtgttgct cgctaatcac taatagatga aagattcgac aggctttatc aatagcctgt
    48421 cgaatttttt atgctgtgag accaagcttt ttgcttagac acataaaaga aacagctcgt
    48481 cagcgccgca tactgcctac ttcattgacc aacaaacagg gcaaactaag gctaattttc
    48541 actgatatga catgtttcga ctataaagcg gttttgtgat tgattgatca caatatcaaa
    48601 ttgctggtga taagggtgca gataacgagc atattgagcg cgcctattga catgatgaac
    48661 tccggattgc gacctctaac gctagtatct ctaccaagcc gcctttggag ctctgtgtca
    48721 ccatctgtat aaaagtaaag cgataagtca aacaactctg gctctaaaaa ggttgtcgac
    48781 atgccttcag caataaggat gggcacattc cccttcacca aaaaagaggg agaccaaggg
    48841 gtatcaatac tcaaaaaatc cagtccttgc ttaaacatca tgatgtcacg cctcagactg
    48901 gccaattcgt gcctagcagg gtgacaggct gttatactac caagtacctc ctctccctga
    48961 tcagggtagc taatcaaaac agcctgacta aaatcattag cgatgatata ggcatctgtt
    49021 tctaacaatt ggctttgtcc atcaggcaaa agctgctgta agcgcttagc aaaggttgat
    49081 ttaccagatg caccatgacc actaattcta ataagcattt tctcacgatt ggctgctgca
    49141 gttacaatag cttgaagtag cttctccatt atctctcctc atcaaataac attctaataa
    49201 taggacatca ttctacatcg aaaaacaagc cggtctcccg aaacagcctg actgacagta
    49261 aaaaaagatt gaagggcaat ccaataagga aagcttctcc aatctgatta atagtctata
    49321 atggcttaat atgagtgcca aatgtcttgg ttatattgtt caatcgtacg gtccgatgaa
    49381 aagaagccag ccttagcaat attatgcaca acctttgtca gccataggtc ctgattgtca
    49441 taatcagcca gcatttgttc tttgactgca atgtattcct caaggtcaat caaggtcata
    49501 aaccagtcct tagagattaa ctccttatag agacggtcaa gacgttcctc attaccaagc
    49561 tctaataatt ctggactgat aataaagtta actgcttcct tgatagctgg gtgggcatca
    49621 taatagtctt tagacacata accacctgtg gcataaagat caataatggt atctgaatcc
    49681 ttaccaaagg tgtagatatt atccatacca gcaagctcag cgatttccac attagccccg
    49741 tccatagtac caagcgtcaa ggcaccattg agcatgaatt tcatattacc agtacctgaa
    49801 gcttcctttg aagctagaga aatttgctct gaaatatcag ttgcaggaat caaatgctct
    49861 gctactgtca cattgtaatt ttcaacaagg tgaacattaa ggtatggact tacctccgga
    49921 tcgttattga taagctctga caagcaaaga atcaaatgaa taatatcctg tgcaatgata
    49981 taagccggtg cagccttacc accaaagata actgttattt tacgcttcgg caggttgcct
    50041 tttttgatct ctaagtattt atgaatcaca taaagggcat tcatctgctg gcgcttatat
    50101 tcgtggaagc gtttaatttg ggtatcaatg attgaatgct catcaagctc aattccctta
    50161 ttatccttga ggtagcgctt taaggctact ttattatggt gcttaatttc agccaatctt
    50221 gcatgaacag cttgatcctc agcaaaggcc attaattttt caagccttgt cgcatcagtc
    50281 aagtaagcat caccgataag ctctttaata tagtccgcca actcttggtt ggcgaattct
    50341 agccaacgac ggaaggtaat accattggtt ttgttgttga atttttctgg atacagctca
    50401 tagaaggcct tcaattcgct atttttcagg atttcagtgt gaagggcagc aacgccgttg
    50461 acacttgtgg caaaatgaat atccatatgt gccatatgca cgcgacctgt ttcatcaatg
    50521 atttggacag ctggatctga tacccttgca cgaacaagag catctaattg ctcgataatc
    50581 gttaccagct gcggcacaac ctcattaagg aagtcaagag gccatttttc caaggcttct
    50641 gcaaggatcg tgtgattggt gtaaccaacc atcttttgaa ccactgaaac agcctcatca
    50701 aaatcaaagc catgcttttg tgtcaataga cgaatcaatt ctggaatgac cattgatgga
    50761 tgggtatcat tgatctgcac gtatgcgtaa tcagctaagt catgcaggtt tgagccacgc
    50821 tcaagcgctt catcgatcaa gagctgagcg gcattagata ccatgaaata ttgctggtaa
    50881 atgcgaagga gctcaccatt tttatcagaa tcatcagggt aaaggaacag ggtcaggttt
    50941 ttggcaatgt cagtcttatc aaatgaaatg ccatctttaa tcaagccata atcaacccct
    51001 tcaatatcaa aaaggttaag atagttcttg gtgtcacgct tatagcccaa aacatcaata
    51061 cggtctaagc gagatttcag ggtaaagttt ttaaagggaa catcatatga aatgtcagtc
    51121 ggtactagcc aagagtcatc ctctatccaa aaattaggct ctgctgtttg ttcattgtgt
    51181 ctaaagacct gcttgaacaa gccacaatga taattcaagc caaccccttc accattaatg
    51241 ccaaggcttg agatagaatc aataaagcaa gaagccaaac gaccaagacc accattacca
    51301 agcgatggct ccaattcaac gtcctctacc tcagcaattg atttgcccgc agcagccagc
    51361 tcctctttga tgtccttata aatacctaga ttaatgagat tattagaaag caacttacca
    51421 atcaaaaatt ctgctgagat gtaataaacc ttacgtttag ctgtgttttt tgcttttttg
    51481 cttgcttctt ctttgagata ggaaagcaac gaaagataga tttcctcgtt gcttgcactt
    51541 gcaagagatt ttcctaatgt catttcagta taatctgtaa agcgtttcat gatatcctct
    51601 tttcaatata gtattctagt gatgattatt ggctcgaccg tatagctcag tcaaatggat
    51661 taaataggcc ttgtgctctg ctttaatatc gtcctcaagc atgcgccact gccagttgcc
    51721 accgacagtg tttggcatat tcatgcggct atcagctgac ttatccagca aatcctgcat
    51781 acacaggata gcagtatcac acacagtcgc aaagattgtt cttagcatgg ccttggtgat
    51841 gctttcagca gctgccttat ggatataatg attaacaaac tcaacctgct ctgcgctcaa
    51901 gtgctcatac cagccattca ccacctcatt gtcatgcgta ccagtgtaga caatgcaatt
    51961 gtgatcatag ttatgcggca aatcaaagct ttgacttgtc acatcaaaca aaccaaactc
    52021 taaaatcttc atgcccggaa agccagtaga tgccagcagc tgctcagcct tttcatcaat
    52081 gtagccaagg ttttctgcga taattggcag ctcacccaag gcctctcgaa cagctttaaa
    52141 tagagcaata ccaggagctg actcccaatg accattttta gcagtcacat caccaccagg
    52201 aatttcccaa aaatctgaga agcccttgaa atggtcaatt ctaagcttat cgtacagctt
    52261 gaagctctct ttgatccgat ggatccacca agcaaagcct gtttgctcat ggctctccca
    52321 gttgtaaata ggattgcccc aaagctgccc gtcctcacta aagccatcag caggtacacc
    52381 tgcaatgtaa atcggctttt tatctgcatc caccttaaag agctctggca tcgtccaaac
    52441 ctcaacgcta tcagcagaca cgtagattgg catatcacca atgatagtaa tgccattttg
    52501 attagcatag gtcttcagcg ctagccactg ctgataaaag aaatattggc agaccttatg
    52561 ataggtgatg cctttggcca acagcttgcg gtaatgaagc aaggcagcct cttcacgctt
    52621 aacaattgct ctatcgtccc attcctggag ggccttgtga tcaaaatgct ctttaatagc
    52681 cataaattca gcaaaatcat ttagccagct cgcagttgct tcaaattcgg cgagctgtct
    52741 taagccttcc tcagttgaga caaaagcctg aactgctttt tctaataaag ggcgtctggc
    52801 ttgaaagact tgagcgtaat caacagactc cggatttgag ccaaaatcaa cagcagcata
    52861 atcagcttcc tgcaaataac cgtcctttgc cagcaattca aggtcaataa aatgcgtatt
    52921 tcctgcaata gctgaaaaag attgataagg agaatctcca aagctagttg ttgttaaggg
    52981 caaaatctgc caataggtct gcttggtttc ctttaaaaag tcaacaaatt caaaggcctc
    53041 tttaccaaag ctcccaatac cgaagcgtcc cggaagcgag ctgatatgca tcagaatacc
    53101 acttgcacgt ttagtcattc tttttttctc cttgtaaaat cttaatgttg aaattataac
    53161 gcaaccgttt gcgcaagtca atatcttttc aaaaaaaaag agactttttc ggcatgctag
    53221 agctgctcaa gccttgataa taatgaggga agcagctagg acaaaaacaa aaaaaggatt
    53281 ggagagacag cctaagcagc tgctcttcca tcctcatctc actcctattt ggcattaata
    53341 tccctgacac tctctcgctt tttgaggcta aagggaacca aaattttctg actcagggtt
    53401 tgttcattgg cattgataat gtctaagagc tgcctaaagg aggttcttcc caaattttca
    53461 acgttaatat caaatgttgt taagtaaggg tgaatcaatt tcgaatagct agaattatta
    53521 aaggtaataa tcgaaatatc atctggcacc ttaatgtcat aaaaggacaa gagctggacc
    53581 attcgcaccg acaaaacatc accaatcacg attaaggctg tggccttaaa gctacgtatc
    53641 gtttcaataa ccttttcgat gcttattgga tcctttcgat caaataacag catcggtttg
    53701 ttttccaagg ataatttcaa gcagcccttg agatagccaa tatagcgctc agaagctacc
    53761 tctgcctcca tatcgtctgt gataaacagg atctgtcggt gacccttttg atagagatga
    53821 tcaactgcgg ttttagccat tagctggttg tcattgtcaa tataggtgat tttgttctca
    53881 tcaccttctg gtgcgccaac aatgacaaaa ggaatctggt tggtcatcaa atagcctcta
    53941 acaggatctt cttgctcaga atataatata ataaagccat caacacgctt ttgcaggtgc
    54001 attaacttaa cctggctcaa taaatcctca acagacatac ctgttgcaat ggaaacagtg
    54061 aaatgatgtt tcttagcttc attggtaatg gtcgatagaa tttccataaa aaagggatca
    54121 ctcaaacgat cattagtgat aatcggcgga aaaaccaggc caatattatg tgtcaggcca
    54181 ctagcaagca tttgcgcagc tacattcgga acatagccaa gctcgctcat agctcttcta
    54241 accttttcct ttgtcttttg ggagatagat cgattatcct tgaggacacg actgacggtc
    54301 gaaggattaa cacctgcttt taaggcaacg tcttttattg taaccatata aacctcattt
    54361 aatacctgat aatgacgcta tgtcaggctt tttcacatgt attttgcttt tattatacaa
    54421 ttatctccta aaaaatcaac tctcgccctg caagaaggcg acataaaaaa ctgctgtcct
    54481 catgatcgaa aaaatgttaa aaaaatcaac tttttttaaa aaaagactag actttttctg
    54541 taaacggttg cataatatta agtgtaagaa atatatctta ggaggaaatc gctatgaaat
    54601 catggcaaaa agttatcgtc agtggggcaa gcttgacact tgctagcgcc ttattagtag
    54661 ggtgtgcatc tggttcaaag gacaaaacag aaactgcatc aggtactgat tcaaaaacaa
    54721 ttaagctttg ggtaccaaca ggagctaaaa agtcatacac agatgttgtc gctaaatttg
    54781 aaaaggactc tggctacaag gttaaggtga tcgagtcaga ggatccaaaa gcacaagaaa
    54841 aaatcaaaaa agatgcttct actgctgccg atgtcttttc acttcctcat gaccagcttg
    54901 gtcagctcgt agaatctggc attatccaag aagtcccaga ggaatacact aaagagatcg
    54961 ctgatacagc aactgatcaa gctatccttg gtgctcaata caagggtaaa acctatgcct
    55021 tcccatttgg tattgagtca caggttctct tctacaacaa aactaagcta gctgctgatg
    55081 atgttgcttc atacgatacc atcacgtcta aggctacctt cggtggtacc ttcaagcagg
    55141 ctaatgctta tgctactggt ccattgttca tgtctgttgg taacacatta tttggtgaaa
    55201 gcggtgaaga cactaaagga actaactggg gcaatgaaaa aggggttgct gttcttaaat
    55261 ggatttcaga ccaagcctca aacaaaggat ttgttaactt agatgccaac aacgtcatgt
    55321 ctcagtttgg agacggttca gttgcttcat ttgaatcagg tccttgggat tacgaggcag
    55381 cacaaaaggc tatcggtaaa gaaaaccttg gtgttgctgt ttatccaaag gtaactatcg
    55441 gtggcgaaac cgttcaacaa aaggccttct tgggagtgaa gctctatgcg gttaaccaag
    55501 ctcctgctaa gggagatacc aagcgtatcg cagccagcta caagcttgct tcatacctaa
    55561 caaatgctga aagccaagaa aaccaattca agacacgtaa catcgtacca gctaacaaga
    55621 ccgttcaagc ttcagaggct gttcaatcaa acgagcttgc aaaaacagtt atcacaatgg
    55681 gatcttcttc agattatact gttgttatgc ctaagcttag tcaaatgggt accttctgga
    55741 ctgaaagtgc tgcaatcctt agcgatgcct tcaatggtaa aatcaaagaa ggtgactacc
    55801 ttgctaagct acagcagttt gacaaggaca ttgcagcaac aaaataagct atctcattta
    55861 taatactatc ctaaacaagt acagaggtgg gctattttaa cgctatcctt tctactcatc
    55921 tctaaagggg tggaactaag catcattatt ttttcagggc ttagtccact cctacttgtt
    55981 tttgatatga cgtaaagctt ggtgctactt aaatttttaa tcgcttaaag atttaggtaa
    56041 cacttagcta tgtggtcgtt agcaccaaac gcttatgacc acagcatctg aacaagagag
    56101 tcaggtaatc ctactttctt gtatcctaac ataaaggaga acatatatga ctcaggcagg
    56161 cttagcatct caggttactg taaaagaggc tttaacaaag ggaagcttcg atattaaact
    56221 atccgctatc atcatgggct ttgccaattt tgctaataaa caattcgtca aaggaacact
    56281 ctttttattg agtgaggtgg tctttttcat cgcctttgtt tcacaaatca ttcctgctat
    56341 tggcggcctc attaccctag gaacacaaac acagggcatg acaaccaaaa ctatcgacgg
    56401 tatcagcatt caggttgctg ttgatggaga caattcgatg ctaatgctga tttttggctt
    56461 agcctctctg attttttgtt tgttatttgc ctatatttat tggtgtaacc taaaaagcgc
    56521 ccgtcacctc tacatgctaa agcaagaagg ggcaaaaatc ccaagcttta aggaggattt
    56581 tgttagtcta gcaaatggtc gtttccatat gaccttgatg acaattccat tgattggtgt
    56641 gcttctgttt acggtacttc ctttgatcta catgatttgc ttagcattta ctaactttga
    56701 tcacaatcac ctcccgccaa agtcactttt tgattgggtt ggtctttcca attttggtaa
    56761 cgtgttaagt ggtcgtatgg caggaacctt ctttcctgtt ttctcatgga cactgatttg
    56821 ggctgtcttt gccacagtga ctaacttctt ctttggtatc attttagcac tcttgattaa
    56881 taccaaaggc ttaaaattga aaaaaatgtg gcggaccttc tttgtgatta ccatcgcagt
    56941 tcctcagttt atttcactgc tgattatgcg aaatctgcta aatgaccaag gtcccttaaa
    57001 tgccctgctt agcaaattag ggttaatcca ccattctcta ccgtttttat ctgatccaat
    57061 ttgggctaaa ttctctatta tttttgttaa tatgtggatc ggtattccat ttaccatgtt
    57121 aatcgcaaca ggtatcatta tgaacctgcc aagcgaacaa attgaggctg cagagattga
    57181 tggggcaagt aaattccagg tcttcaaatc aatcaccttc cctcaaatcc tcattatcat
    57241 gacaccaaac ctgattcagc aatttattgg aaacatcaat aacttcaatg tgatctatct
    57301 cttaactggt ggtgggccaa ccaattcagc ctattaccaa gctggaacca ccgatctatt
    57361 ggtgacttgg ctctataaat tgactgttac agcagcagat tataatctag cctctgttat
    57421 tggtatctta atctttaccg tatcagcaat ctttagctta ctggcttaca caagaactgc
    57481 atcatacaag gaaggagcag cgaaataatg aaaaacaaac gtcgatttca gcttggatta
    57541 gtttacgcca ttttaaccgt tctctcaatc atttggcttt tacctatcgc ttgggttgtt
    57601 ctgactagct ttcgtgctga aggcactgct tatgtcgatt attttcttcc caagcacctc
    57661 acattagacc attatattaa gctctttaca aatgaaacat ttccttttgg gagatggttt
    57721 gtcaatacct ttgttgttgc tatctttacc tgtatcatct caacctttat tacagtggcg
    57781 atggcttact cgcttagtcg gatcaaattc aagtttcgca atcgtttctt aaagcttgca
    57841 ctagtgctaa acatgtttcc aggctttatg agcatgattg ctatctacta tatcctaaaa
    57901 gcacttggcc ttacgcaaag tcttaccgcc ctagtccttg tttattctgc cggtgctgca
    57961 cttggatttt acattgctaa gggcttcttt gataccattc cttattcgct tgacgaatct
    58021 gccatgattg atggggctac tcgtatggat attttcttta agattaccct accgctatca
    58081 aagccaatca ttgtttacac tgcactcctt gcctttatgg gaccttgggt tgactttatc
    58141 tttgcccaag tgattttagg agatgcaacc agcagatata cggtagctat cggactcttt
    58201 tcaatgctgc agcctgacac catcaatgac tggttcatgg cctttaccgc tggatctgtg
    58261 ttaattgcta ttccaatcac attgctcttt atgtttatgc aaaaatacta tgtagagggc
    58321 gttacaggtg gttctgtcaa atagcagtaa tgatcacgat aacccttact caaaaaatcc
    58381 ttccc
//
LOCUS       DARYXW010000003        51404 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.003, whole genome shotgun sequence.
ACCESSION   DARYXW010000003 DARYXW010000000
VERSION     DARYXW010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 51404)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51404)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51404
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.003"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            29..643
                     /locus_tag="TV191_000117"
                     /pseudo
     CDS             29..643
                     /locus_tag="TV191_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677880.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            1173..2051
                     /gene="mvk"
                     /locus_tag="TV191_000118"
     CDS             1173..2051
                     /gene="mvk"
                     /locus_tag="TV191_000118"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEL1506673.1"
                     /translation="MNKTIGYGKAHSKIILMGEHSVVYGYPALALPLKDIEVTCRIFP
                     AAKPLAFDFYDPLSTAVYAALEHLGCLAEPIHYDIMSQVPQKRGMGSSAAVSIAAVRA
                     VFSYFGQPLSDELLEILVNKAEIIAHTNPSGLDAKTCLSDKAIKFIRNVGFDTIDIQL
                     NAYLVIADTGIQGHTREAVNKVAQFEEENLPHLAKLGCFTEAVEQAIKTNDCLAIGRF
                     MTQAHESLKAIGVSVAKADQLVAAALEAGALGAKMTGGGLGGCMIALAERITDAQQIS
                     KKLKEEGAVNTWIQIL"
     gene            2033..2977
                     /gene="mvaD"
                     /locus_tag="TV191_000119"
     CDS             2033..2977
                     /gene="mvaD"
                     /locus_tag="TV191_000119"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEL1506674.1"
                     /translation="MDSNTVTVTSYANIAIVKYWGKKDEAKMIPSTSSISLTLEGMYT
                     TTSLSFLPASAKGDQFYINGVLQDAKEHAKITAILDQFRQKDQTFVKVEASNSMPTAA
                     GLSSSSSGLSALVKACNQLFQAKLSQEELAQKAKFASGSASRSFFGPVAAWDKDTGSI
                     YKVKTDLKLAMIMLVLNDARKPISSREGMKRCSTTSTSFDQWLAQSESDYQAMLRALS
                     DNDFETVGWLTEANALAMHATTKTASPSFSYLTEASYQAMLRVKELRQEGYSCYFTMD
                     AGPNVKVLCLEEDLERLSHLFEREYRIIASKTKELPDV"
     gene            2970..3968
                     /locus_tag="TV191_000120"
     CDS             2970..3968
                     /locus_tag="TV191_000120"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEL1506675.1"
                     /translation="MSKYHVQAGGKLYLTGEYAILRPGQTALICYIPIMLTAVIEAAE
                     AVSISSDMFDHAADLSPDKDYRLIQASIEAFSLYIDKDIKELPAFSLSITGKLERDGK
                     KFGIGSSGSVVVLTLRALAAFYQVQLLPEQLFKLAAYTLLKSGDNGSMGDIACIAYES
                     LVAYTSFDRRKVGQWLIEMTLKELMAAHWGYTIETIEPALPCWFLVGWTQVPSISREM
                     IQLVNKSISCQFLEQSQLVTQEVMTALQLGQRKRLKASIEKAGQLLQGLASVIYHPKL
                     TQLVQACQGLDAAAKSSGSGGGDCGIALVFEAKDIEPILARWQQAGIVLLYQEEWG"
     gene            3971..4963
                     /locus_tag="TV191_000121"
     CDS             3971..4963
                     /locus_tag="TV191_000121"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEL1506676.1"
                     /translation="MTNRKDDHITHALSYHSPYNAFDDMELIHCSLPSYDLADIDLST
                     HFAGCDFEFPFYINAMTGGSKKGQAVNEKLAKVAAATGILMVTGSYSAALKNPEDTSF
                     QLRGVAPDLQLATNIGLDKAVDLGIRAVEEMKPLFLQVHVNAMQELLMPEGERSFKHW
                     KDHLAAYAKQLPVPLILKEVGFGMDIKTITIARDMGVKTFDISGRGGTSFAYIENQRG
                     SNRSYLDDWGQTTVQCLLNAKGLVDEVEILASGGVRHPLDMVKCLVLGARAVGLSRVV
                     LELVETYPVEQIIATINSWKKELKLIMCALDCRTLSDLRQVDYLLYGRLYQANR"
     gene            complement(5248..6531)
                     /locus_tag="TV191_000122"
     CDS             complement(5248..6531)
                     /locus_tag="TV191_000122"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEL1506677.1"
                     /translation="MTKTKPNWAGFYKKSLAERIQQLADDQLLGPQQQKLLETDQLLP
                     IAIANQMTENVIGRLALPFSLAPDFLINGHTYQVPFVTEEPSVVAAASFAAKIIKRSG
                     GFQTEVLSRQMLGQVALYDVKDDEQARLAILANADTLIDVANNAYPSIVKRGGGAKSL
                     TVERKEDFFIVYLSVDTQEAMGANIVNTMMEALVPDLEALSGGQCLMAILSNYATKAL
                     VSAKCQVDLRYLSRHKEEAQQLAKKIELASKLAQIDPYRAATHNKGIFNGIDAVAIAT
                     GNDWRAIEAGAHAYAARTGSYRGLSSWHVDLSKNSLCGELTLPMPIASKGGSIGLNPT
                     VSVAHSLLEQPNAKVLAQITTAVGLAQNFAALKALTSTGIQAGHMKLQAKSLALLAGA
                     SEQEVPQLVKALLKDKPMNLEKAGQLLTAIRLSQS"
     gene            complement(6518..7693)
                     /locus_tag="TV191_000123"
     CDS             complement(6518..7693)
                     /locus_tag="TV191_000123"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEL1506678.1"
                     /translation="MNIGIDKIGFATSQYVLKMEDLALARSTDPAKFHQGLMLDALSI
                     APVTEDIVTLAASAADQILTKDDKASIDMVILATESSIDQSKAASIYVHQLLDIQPFA
                     RSFEIKEACYSATAALDYAKLHVAAHPASKVLVIASDIAKYGIGSAGEPTQGAGSIAM
                     LVTTNPRILQLNHDNVAQTRDVMDFWRPNYSSTPFVNGIYSTKQYLDSLKTTWDKYQE
                     KEGIELSDLAAVCFHIPFPKLALKGLHKIMTKSLADDHKERLYENFQASIAYSKQIGN
                     IYTGSLYLGLLSLLENSQVLRAGDRIGLFSYGSGAVSELFSGQLVDGYKDMLLTNRQA
                     LLDQRQVISVADYEALFYEEPRLDQDGNASFSPYLTGRFALKEIKEHQRIYQDDDKN"
     gene            7878..8717
                     /locus_tag="TV191_000124"
     CDS             7878..8717
                     /locus_tag="TV191_000124"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEL1506679.1"
                     /translation="MTKADHIFKANIKKIMEEGVFSEQARPRYKNGQTANSKYITGAF
                     AEYDLSKGEFPITTLRSIPIKSAIKELFWIYQDQSNSLDVLENKYNVHYWNEWEVGQT
                     RTIGQRYGAIVKKHDIISKILKQLEDNPWNRRNVISLWDYEAFEESEGLLPCAFQVMF
                     DVRRVDGELYLDATLTQRSNDMLVAHHINAMQYVALQLMIAKHFGWKAGKFFYFVNNL
                     HIYDNQFAQAKELLERQPAACQPKLLLHVPDGTDFFDIRPEDFELQDYYPVKPQLTFD
                     LAI"
     gene            8798..9295
                     /locus_tag="TV191_000125"
     CDS             8798..9295
                     /locus_tag="TV191_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEL1506680.1"
                     /translation="MTKKIIAIWAEDEAGLIGACGRLPWYLPKELQHFKETTLNQAIL
                     MGRVTFEGMKGRLLPNRQTLVMTRDSYYHVEGALTITSVQEALDWYHAQDKTLYVIGG
                     SKVLEAFDGYFDVIIKTVVHHQFEGDTYRPRLELSDFVEETSVLYPRDDNNPYDFTVT
                     VLRHR"
     gene            9315..9485
                     /locus_tag="TV191_000126"
     CDS             9315..9485
                     /locus_tag="TV191_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1506681.1"
                     /translation="MQRSIFGVFTAFLCAICVLCAIPAFRKNRYGLGLLFLLNAFTNL
                     VNTIHAFYGTLF"
     gene            9521..10750
                     /gene="clpX"
                     /locus_tag="TV191_000127"
     CDS             9521..10750
                     /gene="clpX"
                     /locus_tag="TV191_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEL1506682.1"
                     /translation="MAGNRSNDIKVHCSFCGKSQDEVKKIIAGNNVFICNECVALSQE
                     IIKEELAEEVLADLTEVPKPKELLEILNQYVIGQERAKRALSVAVYNHYKRISFTESR
                     DDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTV
                     ASVPPQGGRKHPNQEMVQIDTKNILFIVGGAFDGIEEIVKQRLGEKIIGFGQNSRKID
                     DNASYMQEIIAEDIQKFGLIPEFIGRLPVVAALEQLNTEDLIRILTEPRNALVKQYQA
                     LLSYDGVELEFEKGALEAIAGRAIERKTGARGLRSIIEETMLDIMFEVPSQEEVIKVR
                     ITKEAVEGQSKPILEIA"
     gene            10760..11359
                     /locus_tag="TV191_000128"
     CDS             10760..11359
                     /locus_tag="TV191_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEL1506683.1"
                     /translation="MSEEQILNTHNASILLSAANKSHYPQDDLPEIALAGRSNVGKSS
                     FINTILGRKSLARTSSKPGKTQLLNFFNVDDKLRLVDVPGYGYAKVSKAERARWGKMI
                     EEYLTTRQNLRAVVSLVDFRHESSQDDIQMYEFLKYYEIPVIIVATKADKVPRGRWNK
                     HESMVKKSLNFDQTDAFIIFSSVERIGIDESWDTILEYL"
     gene            11723..14725
                     /locus_tag="TV191_000129"
     CDS             11723..14725
                     /locus_tag="TV191_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat domain-containing protein"
                     /protein_id="HEL1506684.1"
                     /translation="MTIKKCPQILALFLAFAALASQGQTVHALERQETSVKQAHESDD
                     WFDEDEGVSDIKSNTPTEIDSTVTELFGDAEPKTKAEKEESKAPSPKQEALPAESQKE
                     KETSAKSTDHATVQAEEAQPEQGSDSPWLADDFVTKGDTLVGLSKAGLAKLSKTPVLV
                     LPRIGIDKTVLTRIASFAFTPNKSVAIADYTGRAGEHGEINHLDVEGRDILTEGEDFG
                     AYAIKKLVIPEGYLFIGQDAFNDNKQLEEISLPDSLLSISDYAFAHMSLSKLKLPKSL
                     QSIGDQAFFDNRIAGTLVLPKALKQLGERVFKSNRLTGLVFEGEGLSVLKEAAFQDNA
                     FISLVIPDSIQALEEDVFTGNLGDEEYGNHAVLRTKNGQNPYRLHSANVLVNPSDQAR
                     TPQPPIDYNRWLAEDFTYTGQTITGFSASGLRKVKRNKHLVLPKNYQGQPLTAIADNA
                     FRNVNFHDKTLRKYDLESVTLPSTIQKIGAFAFQSNNLESFEASEDLVEIGQGAFMNN
                     RIEILALNDKLKVIGDAAFHINRIYAIVIPESVEVIGISAFRQNGAKHVMFMGDKLIS
                     IGEMAFLSNTLEEVDLSSLAGLKTIAVQAFADNHLRELKLPDSLMRIEAEAFKINRLQ
                     RVTVPDTVISISFNAFDHNSDDKVVLRTTNHNKNLLADGNGFIVDPDLLSADQSTVQA
                     VLEDLRRLDLASLRADTAAHFMTLITRGKQLLKESAVRLGYQLRFLAESRFFLGRVRL
                     DQLIKTADITLSSHQDTPNAKLLMAKLDKAKLHYNNSAMTAPKVSRLEKELSLLIDLV
                     QGVGAISKATMTQGVYKLQTTLPIPEYYIGVNLYTDDQGNILFVLDMSDTIGQGQLDD
                     YGNPILNVDEDNEGYHALAIESLADYEGLTIKDILTKELNQLPIRDVKQAREHRVGLF
                     MAIRDAAREAQLLLEKQSKALSESAGKSNGSKVADSGLEPSVTLSTNKTKLLPKTGAF
                     KEAWVTMIGMLVLLAATLLKGDSRYKKK"
     gene            complement(14915..17008)
                     /locus_tag="TV191_000130"
     CDS             complement(14915..17008)
                     /locus_tag="TV191_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEL1506685.1"
                     /translation="MATYYGKDPFENMDDIFNQLMGNIGGYRSENRRYLVNGREMTPE
                     EFQEYRKTGKLAAAEGQEKQASSLKKDGILTKLGTNLTEEARQGRLDPVIGRNDEIQA
                     TAEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGLEA
                     GTQYRGSFEENIQNMVKEVKEAGNIILFFDEIHQILGAGSAGSDSGSKGLADILKPAL
                     SRGELTLIGATTQDEYRNTILKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQHH
                     NVILPDSVLKAAIDYAIQYIPQRSLPDKAIDLVDMTAAHLAAQHPVTDLKSLEAEITK
                     QKELQEKAVAEEDFEKALTAKTRIEELQKQINHHSEGQKVTATVNDIAESVERLTGVP
                     VSNMGASDLERLKEISNRLKGHVIGQDGAVEAVARAIRRNRAGFDDGNRPIGSFLFVG
                     PTGVGKTELAKQLALDMFGSKDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNQNTL
                     TERVRRSPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTINFKNTVIIATSNA
                     GFGHQAGDRADQEPAIMERIAPYFRPEFLNRFNGVIEFNHLAKKDLQEIVALMLTEVN
                     QTLAKKGISLEVTDDVKERLIDLGYDHAMGVRPLRRVIEQEIRDRITDYYLDHPTAKH
                     LLASLDQDTITISEK"
     gene            17379..17798
                     /gene="ndk"
                     /locus_tag="TV191_000131"
     CDS             17379..17798
                     /gene="ndk"
                     /locus_tag="TV191_000131"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEL1506686.1"
                     /translation="MEQTFFMVKPDGVKRGLVGEILRRIERRGFTFDRLELRQATPEL
                     LAKHYDTLINKPFYPELEAYMTSGPVLIGIISGNRVVSSWRTMMGVTNPKDALPGTIR
                     GDFAQAPGDDGGIFNVVHGSDSRDSAKREIAIWFGHS"
     gene            18299..19105
                     /locus_tag="TV191_000132"
     CDS             18299..19105
                     /locus_tag="TV191_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL1506687.1"
                     /translation="MNKQSMTHFSKKLMKLALLGLALPLSLVSVVDTPVLNQSEKAVY
                     ANDFGSGNRASDYVPAANAWSFEAYPDYYSILGASHLNPAVFPEPSKMSYSPLDELGR
                     TQVARGTITYHNIVMNYNVRQRFAKNQNPSGWIGNPRNVRYTIEWLDGLSYQGDFWNR
                     SHLIADSLGGAALRVNAITGTRTQNVGGRNQRGGMRYIEQKVQQWIEQHTSAVVYYEA
                     VPIYQANELVPRAVVVSALSSDGGLDEKVMVYNTANGYTIDYATGAFRSN"
     gene            complement(19397..20362)
                     /locus_tag="TV191_000133"
     CDS             complement(19397..20362)
                     /locus_tag="TV191_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEL1506688.1"
                     /translation="MNNRNKRRKKRKIFKMINLMLLLACIIGLSAIVYLYKSHSKISI
                     SQLSQAIPKISLFSKTDKKPAPKPSKKATNKEASHTNSQQQKGAVSWTKQQNPVKLPI
                     LMYHAIHVMAPEEAASANLIVAPDLFESQLKAMKEAGYYFLSPEEAYRVLSANELPAE
                     KVVWLTFDDSMVDFYNVAFPILKKYDIKATNNVITGFTEAGNAANLTLDQMKEMKQAG
                     MSFQDHTVNHPDLSQASAASQTAEMKDSKEYLDRELHQDTIAIAYPAGRYTDTTLKIA
                     EDLHYKLGVTTNEGLASAANGLLSLNRIRILPTTTADILMNTISQ"
     gene            20534..21817
                     /locus_tag="TV191_000134"
     CDS             20534..21817
                     /locus_tag="TV191_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEL1506689.1"
                     /translation="MSVKVALLGFGTVASGIPLLLENNSSKIRAVVGDDLVIAKVLVR
                     DETTKKRLLDQGYSYQFVTSIDDIVDDESIDMVVELMGRIEPAKTFISRALSAGKPVV
                     TANKDLIALYGGELSTLAAKHQVALYYEAAVAGGIPILRALADSFASDKLTRLLGVLN
                     GTTNFMLTKMIDEGWTYERALQKAQELGYAESDPTNDVKGIDAAYKVAILSQFAFGMT
                     IDFEAISYSGIDKVRVEDVTVAQKLGYVIKLVGLLEETASGLNAEVSPVFLPKTHPLA
                     AVDGVMNAVYIESIGVGQAMFYGPGAGQMPTATAVVADMIQTACTLRDHTVSVFNRFA
                     TKTRLAKSEDIMSPYYFAIQATNKFGQLLELTRLCDVCGIRVEQLLSDEIDSDRLDFV
                     MITHEMSKKELACFTALLQDHQDFRMLSTFKILGD"
     gene            21819..22679
                     /locus_tag="TV191_000135"
     CDS             21819..22679
                     /locus_tag="TV191_000135"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEL1506690.1"
                     /translation="MKIRVPATSANLGPGFDSMGIAVSKYLEVDILEERDQWFIEHDL
                     GDIPNDDSNLLIQTALRLAPNIPAHRLKMTSDIPLARGLGSSSSVIVAGIELANQLGH
                     LNLTDDRKLAIATRIEGHPDNVAPAIFGQLVIASQIGKDVDYIIAPFPDLSLVCFIPD
                     YELKTSDSRDVLPKQLSYKQAVAASSVANLAIAALLTGNLKKAGRAIENDQFHEIYRQ
                     RLVREFQPIKRAAAANGAYATYLSGAGPAIMVMCPNKKKMAIYEAIEQLGLIGQLVSL
                     ELDRQGLCLV"
     gene            22844..24103
                     /locus_tag="TV191_000136"
     CDS             22844..24103
                     /locus_tag="TV191_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEL1506691.1"
                     /translation="MNYQETLDWIHGQERFGIKPGVKRMRWVLEQLGNPQDRIRGIHV
                     VGTNGKGSTVNDLQHIFTRAGYEVGTFTSPYIMDFKERICLNGEMISETDLVKAANCI
                     RPLTDRLISETSLGPATVFELITLIMFLYFGESHPVDIAIIEAGLGGLYDSTNVFQAM
                     AVVCPSIGLDHQAILGDTYADIAYQKAGVLKGGEDLIFAIDNKEARQVFLKKAEQLGV
                     PIWEWRRQFNMLQGEGGYQFNSQLGQLSHLVLAMPGQHQVANAGLATMTSLILQDRYP
                     KVTESVIREALASSFWLGRTELLAPNLMIDGAHNNESIAALIDVISSDYQDKQIHILF
                     GAIDTKPVSDMLQSLERLGDVQVTSFHYPNAYPLEAYPDRLTKVADFRAFLDRLEQAA
                     ADDFFLITGSLYFISEVRQYWKKVLSK"
     gene            24103..24726
                     /gene="folE"
                     /locus_tag="TV191_000137"
     CDS             24103..24726
                     /gene="folE"
                     /locus_tag="TV191_000137"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEL1506692.1"
                     /translation="MLSHINSSNKINQLKRGKPLPINQKKAEAAIYQLLEAIGEDPNR
                     EGLRDTPKRVAKMYLEMLSGLEQDAKDEFTAVFTEHHDDLVIVKDISFYSMCEHHLVP
                     FYGKAHIAYLPSDGRVTGLSKLARAVEVTSKRPQLQERLTAQIANALVDALQPKGVFV
                     MVEAEHMCMTMRGVKKPGSKTITTTARGIYKDSRDDRREVMQLIMEG"
     gene            24734..25534
                     /gene="folP"
                     /locus_tag="TV191_000138"
     CDS             24734..25534
                     /gene="folP"
                     /locus_tag="TV191_000138"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEL1506693.1"
                     /translation="MTIGHYSAAGEAAIMGILNVTPDSFSDGGSYTSVNQALAQAEKM
                     LSEGATVIDIGGESTRPGCQFVPAEEEIARVVPIIKAIKKRYDVLISIDTYKTETARA
                     ALEAGADMLNDVWAGLYDGQMLSLAAEYDVPIILMHNQTKEAYADVTKEVCSFLQARA
                     AAALKAGVKKEHIWLDPGFGFAKNVEQNIALLKGLNEVCQLGYPVLFGISRKRVVDAL
                     LGGGTKAKDRDGATAALSAYAINKGCQMVRVHNVGANRDIVSVLSQLR"
     gene            25541..25900
                     /gene="folB"
                     /locus_tag="TV191_000139"
     CDS             25541..25900
                     /gene="folB"
                     /locus_tag="TV191_000139"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HEL1506694.1"
                     /translation="MDKIRLEACRFYGYHGAFKEEQVLGQIFVVDLELSVDLMAASLS
                     DCLEDTVHYGLVFETVRQIVEEKTFTLIERLAGAICQELFAQFLPIKAIKIAIKKENP
                     PIAGHYQAVGIELERKR"
     gene            25897..26403
                     /gene="folK"
                     /locus_tag="TV191_000140"
     CDS             25897..26403
                     /gene="folK"
                     /locus_tag="TV191_000140"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEL1506695.1"
                     /translation="MTLVYLGLGTNMGDRAGYLQAAVNALSKLPETELLRQSSIYQTA
                     AWGKTDQNAFLNMACQLDTRLTSEALLAATQAIEQALGRVRHEKWGPRTIDIDLLLFG
                     DEPYQSETLVIPHPYMTQRAFVLIPLLEIAPDVTLPGSQKSLRSYLDALEQSDVALWS
                     HEYSNKFS"
     gene            26499..27386
                     /gene="murB"
                     /locus_tag="TV191_000141"
     CDS             26499..27386
                     /gene="murB"
                     /locus_tag="TV191_000141"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEL1506696.1"
                     /translation="MIAELEGIDIRENEALKHYTYTQVGGPADFLAFPRNHYELSRIV
                     DYANHNHIPWMVLGNASNLIVRDGGIRGFVIMFDKLNAVRLNGYTLEAEAGANLIETT
                     KVAKFHSLTGFEFACGIPGSIGGAVFMNAGAYGGEIAHIFLSAKVLTPEGKIKKISAR
                     EMAFGYRHSVIQETGDIVISAKFALKPGNHDSICQEMNRLNHLRKLKQPLEFPSCGSV
                     FKRPPGHFAGQLIMDANLKGHRVGGVEVSKKHAGFMINVADGSAKDYEDLIAHVIRTV
                     EQASGVRLEPEVRIIGESL"
     gene            27432..28586
                     /locus_tag="TV191_000142"
     CDS             27432..28586
                     /locus_tag="TV191_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1506697.1"
                     /translation="MTKPIITFDNVSKTFEDSGTQVLKNINFELEEGKFYTLLGASGS
                     GKSTILNIMAGLLDATSGDIYLDGERINDLPTNKRDIHTVFQNYALFPHMTVFENVAF
                     ALKLKKVDKQEIARRVKETLKMVQLEGYEKRSIQKLSGGQRQRVAIARAIINQPRLVL
                     LDEPLSALDLKLRTEMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVASFIGESNIINGTMIKDYLVSFNGKEFESVDGGMRPNEPVEV
                     VIRPEDLQITLPEEGKLQVKVDTQLFRGVHYEIIAYDDLGNEWMIHSTRKAIEGEVIG
                     LDFTPEDIHIMRLNETEEEFDARIEEYVEIDEHADGLINAIEEERNEENL"
     gene            28570..29364
                     /locus_tag="TV191_000143"
     CDS             28570..29364
                     /locus_tag="TV191_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1506698.1"
                     /translation="MKKTSSLFAVPYFLWIVLFVMAPVALLLYQSFFDIEGRLTLANY
                     ETFFSSWTYLRMGLNSILYAGIVTLVTFLISYPTALLLTRLKHKQLWLMLIILPTWVN
                     LLLKAYAFMGIFGQQGGINSFLTFMGLGPQQILFTDFSFIFVASYIELPFMILPIFNA
                     LDDIDDNIINASKDLGANDYQTFSRVIFPLSLNGVRAGVQSVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLTTENWGMGSTIGVVLIIAMIVIMWLTKEKSK"
     gene            29361..30137
                     /locus_tag="TV191_000144"
     CDS             29361..30137
                     /locus_tag="TV191_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1506699.1"
                     /translation="MKKFANLYLACVFILLYIPIFYLIVYSFNKGGDMNGFSGLTLEH
                     YKTMFDDSRLMAILLQTFVLAFTSALLATIIGTFGAIFIHQSKKKYQNAILSANNVLM
                     VSPDVMIGASFLILFTSLKFQLGILSVLMSHIAFSIPIVVLMVLPRLKEMNQDMINAA
                     YDLGANHFQMLKEVMLPYLTPGIIAGYFMAFTYSLDDFAVTFFLTGNGFTTLSVEIYS
                     RARRGISLDINALSTIVFLFSILLVIGYYYISQDKEEKHA"
     gene            30130..31203
                     /locus_tag="TV191_000145"
     CDS             30130..31203
                     /locus_tag="TV191_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL1506700.1"
                     /translation="MRKLYSFLAGIIGVILLLATLSFILQKKTSSASQSDKLVIYNWG
                     DYIDPALLKKFTKETGIEVQYETFDSNEAMYTKIKQGGTTYDIAVPSDYTIDKMIKEK
                     LLVKLDKSKLVGLDNIGQEFLGKSFDPHNDYSIPYFWGTVGIVYNDQLVDKAPMHWED
                     LWRPEYQNSIMLVDGAREILGVGLTTFGYSVNSKHLKQLEAAEKKLQALTPNVKAIVA
                     DEMKGYMIQGDAAIGVTFSGEASEMLDNNDHLHYVVPSEGSNLWFDNLVLPKTMKHEN
                     EAYAFINFIMKPENAAQNAEYIGYATPNTKAKALLPDDIKNDPAFYPTDETVKKLEVY
                     DNLGSKWLGIYNDLYLQFKMYRK"
     gene            31361..32893
                     /locus_tag="TV191_000146"
     CDS             31361..32893
                     /locus_tag="TV191_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HEL1506701.1"
                     /translation="MENHKNEFTFSKHSIIAYVWRGILVGIIAGAIVSLFRLLIEMVS
                     EAVVGYYHQAHSNRMLLVPIAGFSLLAVFLVGLLVKSDANIKGSGIPHVEGELKGLMS
                     PNWWSVLWKKYLGGTIAISMGLMLGREGPSIQLGAMSAKGLAKYLKSSRLEKRVLIAS
                     GAAAGLSAAFNAPIAGLLFVVEEIYHHFSRLVWITALVASLVANFISLNIFGLRPVLA
                     MPKAMPFLALHQYWLLLILGLVLGCLGFLYEEVILHFHRVYDFLGKSLRLAPHFHGLI
                     VVAIILLIGYYLPQLLGGGHGLIMSLSEQKLPLLTVLAYFFIRFLGSMFSYGSGLPGG
                     IFLPILTLGALSGTIFGLILQQIGLLDRQMIPLFLVLGMAGYFAAVSKAPLTGMILVT
                     EMVGDLKPLMAIAVVTFVAYLVMDLLNGQPIYEAMLEKMAIKHPTDLVEPTLIELPVS
                     EKIAGRYVRDLKLPKNVLITTQLHHKKSQVVSGDTLLISGATIFLVVNEADTGFVREV
                     LM"
     gene            33099..33713
                     /locus_tag="TV191_000147"
     CDS             33099..33713
                     /locus_tag="TV191_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HEL1506702.1"
                     /translation="MLEVISKELRHYQKNKLAAYQKKNQGIEAGGIVFAGDSLIEFFP
                     LKKYFKQVSTIYNRGIAGIDSQWLLEHIDSHVNDLEPSHVFILIGCNDIGLGFDQSHI
                     VSTIVDLISRIRSQSIYTRISLLSLLPVSENPAYQATVKLRTNRAIDEINQALAMIPA
                     IEFIDLNACLKDETGGLAAAYTVDGIHLNALGYEHLAQAISPYL"
     gene            34061..35188
                     /locus_tag="TV191_000148"
     CDS             34061..35188
                     /locus_tag="TV191_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEL1506703.1"
                     /translation="MKFEKKQVFYVVLAFVLCYAIQANWDNGANIVTTVYKTSLPFLY
                     GAAVAYIVNIVMSAYERAYTYTLKPFPFAMKARRGLCMLLAYFTFISLIVWIISIVIP
                     DLIASISSLTQFDTRAIKEVISDLGHNKLIARAINYIGGDAKLTETITNYSQQLLKQF
                     IGVLTGILTSVTAVASAIINVVISFVFSLYVLASKEELCQQATTLIDTYTGKYAKAIH
                     YLVGLLHSRFRGFFVSQTLEAMILGSLTAIGMFILQLPFAGTIGVLVAFTALIPVVGA
                     SIGAAIGFVLIMTQSMSQAVVFIVFLVILQQIEGNFIYPRVVGGSIGLPAMWVLMAIT
                     IGAALKGIVGMIVAVPLAATLYQVVKDHIHKKQALQNRQSS"
     gene            35340..36017
                     /gene="radC"
                     /locus_tag="TV191_000149"
     CDS             35340..36017
                     /gene="radC"
                     /locus_tag="TV191_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEL1506704.1"
                     /translation="MYSIKTDHKLMPRERLIRLGPEKLSNQEQLAILLRTGNKEKHVL
                     ELSAYLLSSLDSLADLKKFSLQELQRLSGIGKVKAIEIKAMLELADRIQIAGQAVADP
                     VLSSAQVAEKMMIELGDKQQEHLVAIYLDSQNKIIEEKTIFIGTVRKSIAEPREILYY
                     ACKNMATSLIVVHNHPSGLTKPSANDYHFTEKIKRSCDYLGLICLDHIIVSKYDYYSF
                     REKSDLF"
     gene            complement(36019..36714)
                     /locus_tag="TV191_000150"
     CDS             complement(36019..36714)
                     /locus_tag="TV191_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEL1506705.1"
                     /translation="MSKTIIGITANQRGTKALDNLPCSYAPTSFIEAVTRSGGLPLLL
                     PIGDEAAAKSYVAMVDKIILIGGQHVDPKYYHEKRAALDGDFSPQRDIFELAIIKEAL
                     AQKKPILGICRGMQLINVALGGSLNQHIEGHWQKTASDCLSQEIVIEKTSPLYPIYGP
                     RALINSFHHQSLKQVAEDLRVIARDPNDGTIEAVISCNPDIPFLGVQWHPELLQAIRE
                     EDLRLFDWFIHSF"
     gene            complement(36726..37370)
                     /locus_tag="TV191_000151"
     CDS             complement(36726..37370)
                     /locus_tag="TV191_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEL1506706.1"
                     /translation="MVIDKSIPKATAKRLSLYYRIFKRFYADQVEKASSKQIADAMGI
                     DSATVRRDFSYFGELGRRGFGYDVTKLMNFFADLLNDHSTTHVILVGCGNIGRALLHY
                     RFHDRNKMQIVMGFDTDDNPMVGTKTPDDIPIYGISTIKEHLDNSGIETAILTVPSIY
                     AQEVADQLIEAGIRGILSFAPLHLQVPKGVIVQSVDLTSELQTLLYFMNQNHLD"
     gene            complement(37656..38003)
                     /locus_tag="TV191_000152"
     CDS             complement(37656..38003)
                     /locus_tag="TV191_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEL1506707.1"
                     /translation="MAFEKEIALKDCKYSYRISPKIKKYTLRDTTFSQTKIGHYQLTR
                     LLEKVPNSGEGFPLKITINKDLDGFKLAITDQSGLRLVNIFKSEEHSILQDKFYFLMD
                     SLVERDIFIKKEC"
     gene            complement(37993..39120)
                     /locus_tag="TV191_000153"
     CDS             complement(37993..39120)
                     /locus_tag="TV191_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEL1506708.1"
                     /translation="MIYFDNAATTSLSQAAIKAMTEAMADDFGNPSSIHAYGRQANKQ
                     LRECRKAIANCLGAAENHIIFTSGGTESNNTAIKGYALAHQEKGKHLITTAIEHHSVL
                     STMAYLEERFGFEVTYLEAKNGIIDLNQLQAALREDTILVSMMFANNETGDLLPIQAV
                     GSMLKQHQAVFHVDAVQAIGKVPIQPADLGIDLLSASAHKFHGPKGTGFLYNKGLKLA
                     PLLHGGNQENKQRAGTESLINIVGMTQALDEAVSRLPQHYQHAKELSQLLLSELEGIS
                     YQLNHNECHLPYIINIGFPGYQNHVLLTQLDLAGFAVSSGSACTAGAVEPSHVLAAYF
                     GKQSHRLTEAIRVSFSEQNTQKDVIALATQLKNILGGSYGI"
     gene            complement(39123..40097)
                     /locus_tag="TV191_000154"
     CDS             complement(39123..40097)
                     /locus_tag="TV191_000154"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEL1506709.1"
                     /translation="MTERYADKQIKLFSLTSNLAIAEKISKAAGIPLGKVSSRQFSDG
                     EIMINIEETVRGDDIYIIQSTSFPVNDNLWELLIMIDACKRASANTVNIVLPYFGYSR
                     QDRVAKSREPITAKLVANMLTKAGIDRVVTLDLHAVQVQGFFDIPVDNLFTVPLFAKH
                     YYPLGLSGPDTVIVSPKNSGIKRARSLAEYLNSPIAIIDYAQDDAEREEGYVIGDVAG
                     KKAILIDDILNTGKTFAEAAKILECAGATDIYAVASHGIFAGGAADILETAPIKEIIV
                     TDSVKTKNRIPKTVTYLSASDLIAEAIIRIHERKPLSPLFSYKPESTN"
     gene            complement(40232..40804)
                     /locus_tag="TV191_000155"
     CDS             complement(40232..40804)
                     /locus_tag="TV191_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEL1506710.1"
                     /translation="MTNLEIEYKTLLTKDEYNRLLSQMTHVPPVTQTNYYIDTDHFDL
                     KAHKMSLRIRTFVAAPAELTLKVPEKVGNREYNLELDDTQAKAIIQTGQLPKSAILDI
                     ISTLDVDLSAIKTFGNLTTIRREADTPIGKLALDYNQYAGIKDYELELEVTDPVRGKV
                     DFDHFLAQHQITFKYSKSKVARFSKTLKKS"
     gene            40899..41570
                     /locus_tag="TV191_000156"
     CDS             40899..41570
                     /locus_tag="TV191_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEL1506711.1"
                     /translation="MALDWEEFLDPYIQTVGELKIKLRGIRKQFRKQNRYSPIEFVTG
                     RVKSVESIKEKMALRGVLEENIAQDIQDIAGLRIMVQFVDDIEDVLSLLRQRQDMTIV
                     YERDYIRNMKSSGYRSYHVVVEYPVDTIEGQKKVLAEIQIRTLAMNFWATIEHSLNYK
                     YGGDFPEEIKKRLEVTAKIALELDEEMRKIREDIREAQLLFDPVTRHLSDGVGNSDDT
                     DELYR"
     gene            41545..42381
                     /locus_tag="TV191_000157"
     CDS             41545..42381
                     /locus_tag="TV191_000157"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEL1506712.1"
                     /translation="MTQMNYTDKVKRVAIIANGKYQSKRLASKLFGVFKDDPSFYLSK
                     KNPDIVISIGGDGMLLSAFHMYEKELDRVRFVGIHTGHLGFYTDYRDFEVDQLIANLR
                     RDTGEQISYPILKVVITLDDGRLFKARALNEATIKRIEKTMVADIIINNVKFESFRGD
                     GISVSTPTGSTAYNKSLGGAVLHPTIEALQLTEISSLNNRVFRTLGSSVIIPKKDKIE
                     LVPKRLGVYTVSVDNKTYHLKNVVKVEYFIGNEKIHFVSSPSHTSFWERVKDAFIGDS
                     ES"
     gene            42378..43280
                     /locus_tag="TV191_000158"
     CDS             42378..43280
                     /locus_tag="TV191_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEL1506713.1"
                     /translation="MRFEFVATKKTKVKTLLKEHDVSKGLLAKIKYKGGNIWVNGVAQ
                     NAIYLLDIGDVVAIDIPNEESFEQLTAISHDLDIVYEDEHFLILNKPAGYASIPSAIH
                     SNTIANFIKAYYIKQDYPNKQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQQRAIN
                     KRYYALVCGQERLPDQGEIIAPIGRTDDSIITRTVTPKGKYAKTSYKVIARYPENVSL
                     VDITLHTGRTHQIRVHFAHLGFPLLGDDLYGGRLDLGMTRQALHCHHLSFTHPFTESR
                     SDHTICLTDDFESVIIDLQKKDRG"
     gene            43284..44285
                     /gene="pta"
                     /locus_tag="TV191_000159"
     CDS             43284..44285
                     /gene="pta"
                     /locus_tag="TV191_000159"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEL1506714.1"
                     /translation="MSIRNLFGGLREKIVGKNMKIVFPEGNDERVVRAAARLKFEGLV
                     EPIILGQADDIRSLLTQLGFAEQHYTIINPNDYADFEKMKAAFVELRKVKATLEDADR
                     LLRDVNYFGVMLVKLGLADGMVSGAIHSTADTVRPALQIIKTKPGISRTSGVFLMNRE
                     NTEQRLVFADCAINIDPTAQELAEIAVNTADTAKIFDIDPKVAMLSFSTMGSAKAPQV
                     EKVQEAVRIAKELRPELALDGELQFDAAFVPSTAAIKAPDSSVAGHANVFVFPDLQSG
                     NIGYKIAQRLGMFDAIGPILQGLNKPVNDLSRGSSAEDIYKLAIITAAQALENESIN"
     gene            44385..45143
                     /locus_tag="TV191_000160"
     CDS             44385..45143
                     /locus_tag="TV191_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEL1506715.1"
                     /translation="MTKIALVTGASAGFGKAIAEQLIAQNIKVIGAARRIEKLRELEG
                     IFGSERFYPLQMDVSEPTAIDKALAELPKEWQAIDILVNNAGLALGLDKAYEADVANW
                     LTMINTNIIGLIYLTRQVLPQMVSSNNGMIINIGSTAGTIPYPGANVYGASKAFVKQF
                     SLNLRADLAGTNIRVTNIEPGLCEGTEFSHVRFKGDHERVKALYAGAHAIQPRDIANT
                     VSWIIDQPEHVNINRVEMMPVSQSYGSQPVSRHD"
     gene            complement(45248..45934)
                     /locus_tag="TV191_000161"
     CDS             complement(45248..45934)
                     /locus_tag="TV191_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HEL1506716.1"
                     /translation="MTKTIYTLALVDDKNNLQKTFFTTLSQEFSYLFHITIVRQLTTE
                     QLKKAQAIFTFQNLEASLPVLYFNQADKEQGFTVSDHTFTDSQQTLRLAKYLMQFYQA
                     LAPHFLTYLPLQARIADHQGQIIFDNHRFNGNFFASDKHDVIEDWILTDLHKAATGSK
                     LYLIPTASQDHIYMQQYQALYDDTKQFVGVYDMILDFKPMLQHYLEETGQAIVGWSDV
                     TSGPSLSDHF"
     gene            46189..46917
                     /locus_tag="TV191_000162"
                     /pseudo
     CDS             46189..46917
                     /locus_tag="TV191_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922297.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            46910..48442
                     /locus_tag="TV191_000163"
                     /pseudo
     CDS             46910..48442
                     /locus_tag="TV191_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_028398951.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
     gene            48800..49783
                     /gene="guaC"
                     /locus_tag="TV191_000164"
     CDS             48800..49783
                     /gene="guaC"
                     /locus_tag="TV191_000164"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007891361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEL1506717.1"
                     /translation="MFNDMPVFDYEDIQLIPNKCIINSRSEADTSVRLGNYTFKLPVI
                     PANMQTIIDETIAEQLARDGYFYIMHRFDEEGRKPFIQRMHEQQLIASISVGVKDYEY
                     DFVSSLKEDAPEFITIDIAHGHADSVIKMIKHIKAELPETFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAAVRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGATMVMIGSLFAGHIESPGKMVEIDGQSFKEYYGSASEYQKGEHKNVEGKKIL
                     LPTKGHLADTLTEMKQDLQSSISYAGGRDLESLRRVNYVIVKNSIWNGDSI"
     gene            49969..50550
                     /locus_tag="TV191_000165"
     CDS             49969..50550
                     /locus_tag="TV191_000165"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEL1506718.1"
                     /translation="MRLLEERILADGTVLGETILKVDQFLTHQVDYRLMKEIGRVFAD
                     QYADLGITKVVTIEASGIAPAVYTAEALEVPMIFAKKHKNITMTEGILTAEVYSFTKQ
                     VTSTVSIAGGLLSKEDRVLIIDDFLANGQAAKGLIDIIHQAGAKAVGIGIVIEKSFQA
                     GRQLLEDLGVEVTSLARIKHFDNGIVSFLEADA"
     gene            complement(50838..>51404)
                     /locus_tag="TV191_000166"
     CDS             complement(50838..>51404)
                     /locus_tag="TV191_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEL1506719.1"
                     /translation="LDQSLGSIFLKEKGMSIDLGALAKGYIADKLMAFLIKDGITAAL
                     INLGGNVLVHGTNKQRHNGLFYVGIQQTNQKRGQHVGVIKVNNKSVVTSGIGERQLQI
                     KDKTYHHLLDPHNGYPIKTNMASLTIVSQFSLDGELWSSRLFGLEHSFVLSQLNKLPE
                     VEGIIITKDGQVTISDGLKGAFRLHYKH"
BASE COUNT        14498 a         9749 c        11791 g        15366 t
ORIGIN      
        1 attctatatc aattgcttga cattgtaggg aaagtcctct atcatgaatt tgctgtatcg
       61 cttttatgat gtacaatcag gcctcattac agttgatggg caaaatattc aggagtattc
      121 tagagaaagc ctgcgttcac agatgggtat tgtcttgcag gatccttatt tgtttacagg
      181 aacgattgct tctaatatca cgatgggaaa tccagcttat tcggatcagg atattttaga
      241 tgctttggaa aaggtcggag cctcttcgat gattgctcgt ctggaaaagg gcattcatga
      301 gcctgtctat gaaaaaggct cctcttattc aagtggcgag cggcagctaa ttgcttttgc
      361 taggacattg attgccgacc ctaaaatttt gatcttagat gaagcgacct cgcacattga
      421 tactgagaca gaggacatca ttcaacaggc tatggaggtc ttaaagaaag gccgaacaac
      481 ctttatcatt gcccatcgct tgtctaccat tcaatctgct aatcaaattt tagtattgga
      541 taaggggagg atcgtcgaaa gaggaacaca tcaggaattg ctagatcagc aaggcattta
      601 tgctgaaatg tccaagctac aagaaaaggt ggctgtacag taatgctttt tagtgatagc
      661 tatcaaaaaa ttccttttct aggccgtgtt aagcagcagt agtctgtgaa gtaggagcta
      721 tatttaggtt ttgtgcctaa gcctttaagg tttttaagag gctggattag ggcttaacat
      781 caataaaatc atatgtcact ttatcacagc atgttgtggt gaagtgtttt ttgtgtcgtc
      841 ctgctaaagg gaagatcctc acagtcaggg cttggctggc tcctttatca gagtcagatc
      901 attcatacgt acttcctgtc aggcttggct aagttgaatt gtatgttgag atcagcatgt
      961 cagcaattta tgctttgtgt ctgactttta gcagcttgta catgaaatag gactaaagga
     1021 cacttgaatt gatgaagaat cagcttaaaa accatttgtc ctagatagga taagaactgt
     1081 ctaaaagggg gatagatcat cgcaattttt aacaatttag tgtaaaatag taaggtgaat
     1141 gttttgatga aataaacgaa aagatttagg atatgaataa gacaattgga tatggcaagg
     1201 cacacagcaa aatcatttta atgggtgagc attctgtggt ctatggctac cctgcgttgg
     1261 ccttgccctt aaaagatatt gaagtgacct gccggatttt ccctgctgca aagcccttag
     1321 cctttgattt ttatgatccc ttatcaacgg cagtttatgc agccttggag catttggggt
     1381 gcttggcaga gcccattcat tatgatatta tgtctcaggt accacaaaag cggggcatgg
     1441 gctcctcagc agctgtttcg attgcagctg ttcgagctgt tttttcttat tttgggcagc
     1501 ccttgtcaga tgagctgttg gaaatcttgg tgaataaggc agaaatcatt gctcacacca
     1561 atcccagtgg cctagatgct aagacctgcc tcagtgataa ggccatcaaa tttattagaa
     1621 atgttggttt tgataccatt gatattcagt taaatgctta tttggtcatt gctgatacag
     1681 ggattcaggg gcatacgcgt gaggctgtca ataaggtggc tcaatttgag gaggaaaatc
     1741 ttcctcattt agccaagctt ggctgtttca cagaggctgt tgagcaagca attaagacaa
     1801 acgattgcct agctattgga cgattcatga cgcaggcaca tgaatcacta aaggctattg
     1861 gtgtcagtgt ggcaaaggct gatcagctgg ttgcagcagc tcttgaggct ggcgctttag
     1921 gagctaaaat gactggtggt ggcttaggag gatgtatgat tgcattagct gaaaggataa
     1981 cagacgctca gcaaatcagt aagaaactaa aagaagaggg agctgtaaat acgtggattc
     2041 aaatactgta acggtaactt cctacgctaa tattgctatt gtcaaatact gggggaaaaa
     2101 agatgaggct aagatgatcc catcaacctc tagtatttct ttgaccttgg aaggcatgta
     2161 cacgacaaca agtctttctt ttttgcctgc ctcagcaaag ggagatcagt tttatatcaa
     2221 tggtgttctg caggacgcca aggagcatgc taagattact gcgattttgg atcagttccg
     2281 tcagaaggac cagacttttg tcaaggttga agccagcaac agcatgccaa ctgcggcagg
     2341 cttatcctca agctctagtg gcttatctgc tctggtaaag gcctgcaatc agctttttca
     2401 agctaagcta agtcaagaag agcttgccca aaaggctaag tttgcctctg gctctgcttc
     2461 gcgttctttt tttggccctg ttgctgcctg ggataaggat acaggctcta tttataaggt
     2521 caaaacagat ttaaagctgg ccatgattat gctggtcttg aacgatgcta gaaagcccat
     2581 ttcgagtcga gaggggatga agcgctgcag cacaacctca acaagctttg accagtggct
     2641 ggcccagtca gaaagtgatt atcaggccat gttgcgtgcc cttagtgaca atgattttga
     2701 aacggttggt tggctgacag aagcaaatgc tctagccatg cacgcaacga ccaaaacagc
     2761 cagtccttcc ttctcttacc taacagaggc ctcctatcag gccatgctaa gggtcaaaga
     2821 gcttcgtcaa gagggctatt cttgctattt tacgatggac gctggtccaa atgtcaaggt
     2881 gctttgttta gaagaggact tagagcggct gtcgcacctt tttgaaaggg agtatcgtat
     2941 catcgcctca aaaacaaagg aattaccaga tgtctaaata tcatgttcaa gcaggaggaa
     3001 agctgtatct gacaggcgaa tatgcgattc taaggccggg gcaaacggcg ttgatttgct
     3061 atattcccat aatgctgaca gctgtcattg aagcagcaga ggctgttagt atcagctcag
     3121 atatgtttga ccatgctgct gatttgtcac cggataagga ttataggctg attcaagcct
     3181 ctattgaagc ctttagttta tatatagata aggatattaa ggagctgcca gccttttctt
     3241 tgtctattac tggtaagctt gagcgtgacg gtaaaaagtt tgggattggc tctagcggta
     3301 gtgttgttgt actaacgcta agagctttgg cagcctttta tcaggttcag ctgctaccag
     3361 agcagctctt taagctggct gcttataccc tgcttaaatc aggagataat ggctccatgg
     3421 gggacattgc ctgcattgcc tatgagagct tggttgctta tacatccttt gataggcgta
     3481 aggttggtca atggttgatc gagatgaccc taaaagagct aatggcagca cattgggggt
     3541 atacgattga gactattgag cctgctctgc cctgttggtt tcttgttggc tggacccaag
     3601 tcccttctat ctcaagagag atgattcagc tggttaacaa gagcattagc tgtcagtttt
     3661 tagagcaaag ccagctggtc acacaggaag tgatgactgc cctgcagctt ggtcaaagaa
     3721 aaaggctcaa agctagcatt gaaaaagcgg gtcagttgct gcaagggttg gcttcagtta
     3781 tttatcaccc taagcttacg cagcttgtcc aggcttgtca agggcttgat gctgctgcca
     3841 aatcatcagg ctcaggaggt ggggattgtg gtattgcact cgtttttgag gctaaggaca
     3901 ttgagcctat ccttgccaga tggcagcaag cagggattgt attactatat caggaggaat
     3961 ggggataaac atgactaatc gtaaggatga ccatatcaca catgctttga gctatcattc
     4021 tccttacaat gcatttgacg acatggagct cattcactgt tccttgccga gctatgattt
     4081 agctgatatt gatctctcaa cccattttgc tggctgtgat tttgagtttc ctttttatat
     4141 caatgcgatg acaggtggta gcaagaaagg ccaagcagtc aatgaaaagc tggccaaagt
     4201 ggctgcggct acaggtattt taatggtgac aggctcttac agtgcagcct tgaaaaatcc
     4261 tgaggacact tcctttcaat tgcgaggtgt agcaccagat ttacagttgg ccaccaacat
     4321 tggtcttgat aaggctgttg acctagggat tagagctgtc gaggaaatga agcccttgtt
     4381 tttacaggta catgtgaatg ccatgcagga gctgttaatg ccagagggag agcgcagctt
     4441 taagcattgg aaggatcatt tagcggccta tgccaagcag cttccagtcc ctttgatttt
     4501 aaaagaggtt ggctttggta tggatattaa gaccatcact atagcacgtg atatgggagt
     4561 aaaaaccttt gatatttcag gaagaggagg aacctccttt gcctacatcg aaaatcaaag
     4621 aggaagtaat cgctcttacc tagacgattg gggacagaca acagtgcaat gtctattaaa
     4681 cgccaaaggt ctggttgatg aagtggagat cttagcctca ggtggtgtca gacacccctt
     4741 agatatggtt aaatgcttgg tgctgggggc acgtgctgtg ggcctatcgc gagtggtatt
     4801 ggagttagtt gagacctatc cagttgagca gatcatcgct acgatcaata gctggaagaa
     4861 ggagcttaag ctcatcatgt gtgctttaga ttgtcgaacc ttgagcgatt tgcgtcaggt
     4921 ggattattta ttatatggta ggctttatca ggcaaaccgc taaagacttt ttagccctga
     4981 gctaactttc cttagaaaat catcacagga gttaagaagc tgcctgcttg gtgctgcaag
     5041 ctaattcagc tgattatggc tcgtaagatt tttagatgtc tgaatgaaat gataggacag
     5101 atgacatagt atagcgctaa tttctagtga aaatcagtcc ttggtcaggt tactgagact
     5161 gaggttaagt ttatgtttac actaacactt aaaggatatg aaaacacttg gtagctgcca
     5221 ctgaagctgt taccaagtgt ttttagtcta tgattggctt aatcgtatgg ctgttaagag
     5281 ctgtcctgcc ttttctaggt tcattggctt atcctttagt agagccttaa ctagttgagg
     5341 cacctcctgc tcactagcac ctgctaatag agctagagac ttggcctgca gcttcatgtg
     5401 accagcctgg ataccagttg aggtcaaagc ctttagagcc gcaaaatttt gcgccagccc
     5461 aactgcagtg gtgatttggg cgagaacctt agcatttggt tgctctaaaa ggctatgagc
     5521 aacactgacg gttgggttga gaccgatcga ccctccttta ctagcaatgg gcattggcag
     5581 tgttagctct ccgcataagc tatttttaga taaatcaacg tgccagctac ttagccctct
     5641 ataagagcca gtccttgcgg cataggcatg tgctccagcc tcaatagctc tccagtcatt
     5701 tccggtagct atagctaccg catcgattcc attaaagatt cccttattat gcgttgctgc
     5761 tcggtaaggg tcaatctggg ctaatttgct tgccagctct atttttttgg ccaattgctg
     5821 agcttcttcc ttatgtcgac ttaggtatct gaggtcaacc tgacatttag cactaactaa
     5881 agcttttgtt gcatagtttg agaggatagc cattaagcat tgaccaccgc ttagggcctc
     5941 caaatcaggt actaaagcct ccatcatcgt gttaacgatg ttggctccca tagcctcttg
     6001 ggtatcaacg ctcagataga caatgaaaaa atcctcctta cgctcaacgg taaggctctt
     6061 tgcgccacca ccacgcttaa caatagaagg gtaggcattg tttgcaacgt caatcaatgt
     6121 atctgcgtta gctagaatag ccagcctagc ctgctcgtca tctttaacat cataaagagc
     6181 tacctgccca agcatttgac gactgagtac ctcagtctga aagccacctg atcgcttgat
     6241 gattttggca gcaaaggaag cagcagcaac aacagaaggc tcttcagtca caaaggggac
     6301 ctgataggta tgcccattga tcagaaaatc aggggctaga ctaaaaggca gagccagtcg
     6361 accgatgaca ttttcggtca tttgattggc aatagcaatg ggtaagagct ggtctgtctc
     6421 taacagcttt tgctgctgcg ggccaagcag ctggtcatct gcgagctgtt gaatgcgttc
     6481 tgcaaggctt tttttataaa agccggccca atttggttta gtttttgtca tcatcttgat
     6541 aaattcgttg gtgttcctta atttctttga gggcaaacct gccagttaga tatggtgaaa
     6601 agctggcatt gccatcttgg tctagtctag gctcttcata aaaaagtgct tcataatcag
     6661 ccactgaaat cacctgacgt tggtctaata gggcttgtcg attagtcagt agcatgtcct
     6721 tgtaaccgtc aacaagctgc cctgaaaaca gctcactaac agctcctgag ccatagctaa
     6781 acaatccaat cctatcacca gcccttagca cctgactatt ctctaaaagt gataataagc
     6841 cgaggtagag tgagcctgtg taaatgttgc cgatttgctt gctgtaggca atagaagctt
     6901 gaaagttttc ataaagcctt tctttgtgat catctgctag tgattttgtc atgatcttat
     6961 gaagtccctt tagagcaagc tttggaaagg ggatatgaaa acaaacagca gcaaggtctg
     7021 atagctcaat accttctttt tcttggtatt tgtcccaggt tgtttttagg gaatcaaggt
     7081 attgcttggt cgaataaata ccattgacaa atggtgttga gctgtaattt ggacgccaaa
     7141 aatccatcac atcacgtgtc tgtgcgacat tgtcatgatt taactggaga atacgaggat
     7201 tagtagtaac tagcatagca atacttccag caccttgtgt tggctctccg gcggatccaa
     7261 tgccgtattt ggcgatgtca ctggcaatga ccaagacctt ggaggctggg tgtgcagcaa
     7321 catgtaattt ggcataatct aaagcagcag tagcgctgta gcaggcttcc tttatctcaa
     7381 aggagcgtgc aaagggctga atatcaagca gctgatgaac gtaaatactg gctgcctttg
     7441 attgatcaat gcttgattcg gttgctaaaa tgaccatgtc aatgcttgct ttatcgtctt
     7501 tggtaaggat ttggtcagca gctgatgcag caagcgttac aatatcctct gtaacaggtg
     7561 caatgcttag agcgtcaagc attagcccct gatgaaattt tgctggatca gtgctgcgag
     7621 caagtgccag gtcttccatt tttaagacgt attgactggt cgcaaagcca atcttatcaa
     7681 ttccgatgtt cataaatatc cttcttttat ccattttata gtcctatcca ttttatcata
     7741 ttttcttaga aaattagctg atttaatacg atagttttac ctttcaaacc aaaaacagca
     7801 gcatatagct ttcttctggt atttttgaag gaaattagat aaaataatat ggactgtgct
     7861 tacagaaagg ggtttccatg acaaaagcag atcatatttt taaagctaat atcaaaaaaa
     7921 ttatggagga gggagtcttt agcgagcagg ctcgcccaag gtacaaaaat ggtcaaacag
     7981 ccaattccaa atacattaca ggtgcttttg cagagtatga tttgtctaag ggagagtttc
     8041 ctattacaac tctaagatca atccctatca agtcagctat taaagagtta ttttggattt
     8101 atcaggacca atcaaacagc cttgatgttt tagaaaacaa atacaacgtt cactattgga
     8161 atgagtggga ggtcggtcag acaagaacca tcggtcagcg ctacggtgca atcgttaaaa
     8221 agcatgatat catctcaaaa atcctcaagc agctagagga caacccttgg aatcgccgaa
     8281 atgtgatttc tctgtgggat tacgaagcct ttgaagaatc agaaggactg ctaccatgtg
     8341 cctttcaggt gatgtttgat gttaggcgag tagatggtga gctgtattta gatgccacgc
     8401 tgacccagcg ctcaaatgat atgctagtgg ctcatcatat caatgccatg caatatgttg
     8461 ccctgcagct aatgattgcc aagcattttg gctggaaggc tggtaagttc ttttattttg
     8521 tcaataattt gcacatctat gacaaccaat ttgcgcaagc caaggagcta ttggagcgtc
     8581 agccagcagc ctgtcagccc aagcttttgc tgcatgttcc tgatgggaca gacttttttg
     8641 atataagacc agaggatttt gagctacagg attattaccc agtgaagcct cagctcacct
     8701 ttgacttggc gatttaagcg aaaaagacga ttttttctga gcattttgcc aagaaatttg
     8761 atagaataaa agaagttcat attgaggaaa gctagtgatg acaaagaaga ttattgctat
     8821 ttgggcagag gatgaagcag gacttatcgg agcgtgtggc aggcttcctt ggtacctacc
     8881 aaaagagttg cagcatttca aggaaacaac attgaatcaa gctatcctga tgggacgagt
     8941 aacctttgag ggcatgaagg gtcgtttgct gccaaatcgc caaacgcttg ttatgaccag
     9001 agacagttat tatcatgtgg agggcgcttt aaccataacc agtgtgcagg aggctttgga
     9061 ttggtatcat gcgcaggata agaccttata tgtgattggt ggcagcaagg ttttagaggc
     9121 ctttgatggt tattttgatg tcatcatcaa aacagtggta catcaccagt ttgagggtga
     9181 tacctaccga cctaggttag agctgagtga ttttgtagag gagacctctg tattgtaccc
     9241 aagggacgat aacaatcctt acgatttcac tgttacagta ttgagacatc gctaatatag
     9301 ggagatgata gtctatgcag cgtagtattt ttggggtatt tacggccttt ttgtgtgcga
     9361 tttgtgtttt atgtgccata ccggccttta gaaaaaatcg ctatggctta ggattacttt
     9421 ttttattaaa tgcctttact aacctagtga ataccataca tgccttttat ggaacactgt
     9481 tttaagccta agagaatgaa aagagaaaga tagaggaatc atggcaggaa atcgtagtaa
     9541 cgatattaag gttcattgct cgttttgcgg caagagccaa gacgaagtga aaaaaattat
     9601 tgcaggtaat aacgtcttta tttgtaacga atgtgttgcc ttatcacaag aaatcatcaa
     9661 ggaagaattg gcagaagagg ttctcgctga tctgactgag gtaccaaagc caaaagagct
     9721 gcttgagatt ttaaatcaat acgtcattgg gcaggagcgt gctaagagag ccttatcagt
     9781 tgcagtttac aaccactaca agaggatttc atttactgag agtcgtgatg atgatgatgt
     9841 ggatttgcag aagtccaata ttctgatgat tggaccaaca ggctcaggaa agaccttttt
     9901 ggcacagacc ctggctaaga gtctgaatgt tccgtttgct attgctgatg caacctcttt
     9961 gactgaggca ggctatgtcg gagaagatgt ggaaaatatc ctcctgaaat taattcaagc
    10021 cgctgattac aatgttgagc gtgcagagcg cggcattatt tatgttgacg aaattgataa
    10081 aatcgctaaa aaaggtgaga atgtctctat cactcgtgac gtatcaggag aaggtgtcca
    10141 acaagccttg ctaaaaatca ttgaaggaac ggttgctagt gttccaccgc aaggtggtcg
    10201 taagcaccca aaccaagaga tggtacagat tgataccaaa aatatcttgt ttatcgtcgg
    10261 aggcgccttt gatggtatcg aagaaattgt caagcagcgc ttgggagaaa agatcattgg
    10321 ctttgggcaa aatagtcgaa agattgatga caatgcttcc tatatgcagg agatcattgc
    10381 tgaggatatt caaaaatttg gtctgattcc cgaatttatt ggacgcttgc ctgttgtggc
    10441 agcgcttgag cagcttaata ctgaggattt gattcgtatt ttaacagagc ctagaaatgc
    10501 ccttgtgaag caatatcaag ccttattgtc atatgatggc gtagagcttg agtttgaaaa
    10561 gggggctctg gaggctattg caggtagggc tattgagcgc aagactggtg cgcgtggtct
    10621 gaggtctatt attgaagaaa ccatgctgga tatcatgttt gaggtgccaa gccaagagga
    10681 agtaatcaag gtacgcatta ctaaggaagc tgtcgaaggt caatcaaagc ctattttaga
    10741 gatagcctaa ggaggtatga tgtctgaaga gcaaatcctt aacacgcata atgcttcgat
    10801 attgcttagt gcggcaaata agtctcatta cccacaagac gaccttcctg agattgcttt
    10861 ggcaggtcgg tcaaatgttg gaaaatcaag ctttatcaat actatactag gacgtaaaag
    10921 ccttgctaga acctcaagca aacctggtaa aactcagctt cttaattttt ttaacgttga
    10981 tgataagcta aggcttgttg acgttcctgg ctatggttat gctaaggtat ctaaggcaga
    11041 gcgggctaga tggggaaaga tgatcgaaga gtacctgacc acacgacaaa atctcagagc
    11101 agttgttagt ctggttgatt ttcgccatga gtcatcacag gacgacattc agatgtatga
    11161 gtttttgaag tattatgaga ttccggtgat tattgtggct acaaaggcag acaaggttcc
    11221 tcgtggtcgc tggaataagc atgagtctat ggttaaaaag tccttaaact ttgatcaaac
    11281 agatgcgttt attatttttt catctgttga gcgtatcggt attgatgagt cttgggatac
    11341 cattttagag tatttataag catatggtaa aaaatttaag tatcttttag acaggcactt
    11401 gtgtctggtc tgagaggtgc ttttttattg acaaaaaaac aatttgttga tgacgagctt
    11461 gtgttcaaaa atgtcagttt gctaaaaaat gatgataaca aacaagactt ttatgatata
    11521 atgcttagca ggataatatg gagacatgag aaaaaggtca gagacagcta atttgctatc
    11581 cctgattata actatgatga ccagcattat tataatactc atggtgctag ctattagtag
    11641 cagcacctaa cctatagtgt tgctttttag gttacaagca ctggcgctag gagtattata
    11701 atatatttag aaaggttttt ttatgacaat aaaaaaatgc cctcaaatac ttgccttatt
    11761 ccttgctttt gcagcgctag ctagtcaggg gcaaaccgtc catgctctgg agcggcagga
    11821 gacatctgtc aagcaagctc atgaatcaga tgattggttt gatgaggacg aaggagttag
    11881 cgatatcaag tctaataccc ctacagagat agactcaaca gtaacagagt tatttggtga
    11941 tgctgagcct aagactaagg ctgaaaaaga agagtcaaaa gctccaagcc ctaagcaaga
    12001 agcactgcca gcagagtctc aaaaagaaaa agagacatct gctaaatcga ctgaccatgc
    12061 gacagtacaa gcagaagagg cacagcctga gcaaggctca gatagtcctt ggctagcaga
    12121 tgactttgtt actaagggag ataccttggt tgggctatct aaggcaggtc ttgctaagtt
    12181 atcaaagaca cctgtcttgg tactaccaag gatagggatt gacaagacag tgttgacaag
    12241 gattgctagc tttgccttta ctccaaataa atcagtcgct attgctgatt atacaggtag
    12301 agcaggtgaa catggcgaga tcaatcatct ggacgtcgaa ggcagagata tccttactga
    12361 gggagaggat tttggtgcct atgcgattaa aaagcttgtg attcctgaag gctatctttt
    12421 tatcggtcaa gatgccttta atgacaataa acagctagaa gaaatcagtc tacctgatag
    12481 cttactcagt atttcagact atgcctttgc tcacatgagt ttatctaagc ttaagctgcc
    12541 aaaaagccta cagtccattg gagatcaagc cttttttgat aatcggattg caggcacttt
    12601 ggtattgcca aaagctctaa agcagctggg agaacgcgtc tttaagtcca atcgcctcac
    12661 tggacttgtc tttgagggag aaggcttgtc tgtcctaaaa gaagcagcct ttcaagacaa
    12721 tgctttcatt agtcttgtta tcccagatag cattcaagcc ttagaagagg acgtctttac
    12781 aggaaacctt ggcgatgaag aatacggtaa tcatgccgtt ttacgaacca aaaatggtca
    12841 gaatccttac agacttcaca gtgccaatgt tcttgtcaat ccaagtgatc aggctagaac
    12901 accacagcca ccaattgatt acaacaggtg gcttgcagaa gattttacct atactggaca
    12961 gacgataacc ggtttttcag ctagtggact gcgcaaggtc aaacgcaata agcatttggt
    13021 tctgcctaag aattatcagg gtcagccctt gacagccatt gcagataatg cctttagaaa
    13081 tgtcaatttt catgataaaa ccttgcgtaa atacgaccta gaaagcgtga cgttaccatc
    13141 taccattcaa aagattggtg cctttgcctt tcagtcaaat aatctagaaa gctttgaggc
    13201 cagcgaggac ttggttgaga ttggtcaagg agcctttatg aataatcgca ttgagattct
    13261 ggccttgaat gataagctga aggtcattgg agatgcggcc tttcatatca atcggattta
    13321 tgctattgtt atccctgagt cggtcgaagt aattggcatt tctgccttta ggcaaaatgg
    13381 tgctaaacat gtgatgttta tgggagataa gctaataagt attggagaaa tggctttttt
    13441 gagcaatact ctggaggaag tggatttgag cagcttagca gggcttaaga ccatcgctgt
    13501 tcaagccttt gcagacaatc acttgagaga gcttaagctg ccagatagtt tgatgcgtat
    13561 tgaagcagaa gcttttaaaa ttaatagact tcaaagagtg accgttccag acactgtcat
    13621 tagcattagc tttaatgcct ttgatcataa tagtgatgac aaggttgtcc taaggaccac
    13681 caatcacaat aaaaacctgc tagctgatgg aaatggcttt attgtggatc cagacctatt
    13741 aagtgcggat caatcgactg ttcaagcagt tttagaggac ctgcggcgct tagatctagc
    13801 tagtctacgt gctgatacag cagctcattt tatgacactc atcacaagag gtaagcagct
    13861 actaaaagaa tccgctgtac ggttaggtta tcagcttagg ttccttgcag agtcacgatt
    13921 tttcttaggg cgcgtgagac tggatcagct gattaaaact gctgacataa ccctatctag
    13981 ccatcaagac acacctaatg ctaagctgtt gatggctaag ctagacaagg ccaagctgca
    14041 ttacaataat agcgcaatga ctgctccaaa agtaagtcgc ttggaaaaag agctcagcct
    14101 gttaattgat cttgtccaag gggtaggcgc tatctctaaa gcaacaatga ctcaaggtgt
    14161 ctataagctt cagacaaccc tacctattcc agagtattat attggggtta atctttatac
    14221 tgatgatcag gggaatattt tatttgtgct tgacatgagt gatacgattg ggcagggaca
    14281 acttgatgac tatggcaatc ctattttaaa tgttgatgag gataatgaag gctaccatgc
    14341 tttggccatt gagtccttag cagattacga aggccttacg attaaggata tattgaccaa
    14401 ggagctaaat caattgccta ttcgcgatgt caagcaagca agagagcatc gtgttggtct
    14461 ttttatggca atcagagatg ctgcaaggga agctcagctt ctactagaaa agcagagcaa
    14521 agccttatca gaatcagccg gcaaatctaa tggctcaaaa gtagctgact caggacttga
    14581 gccttctgtg acactatcaa ccaataagac taagctgcta ccaaaaacag gagccttcaa
    14641 agaagcttgg gtgacaatga tcggaatgct tgttcttttg gcggctaccc tacttaaagg
    14701 cgatagtcgc tacaaaaaga agtaaatagg cttgcttagc aagcacactc tagcaccagt
    14761 aaggcttgag gggcttacaa agcctatcta atctagcaat agtatattgc cagtgtgagc
    14821 tggtgcttga gcttcaaaaa aacaaaagag cctgaaatga cttttactag catttcaggc
    14881 tctttttagc ttgtgattct tttttgtgtg aagcttactt ctcacttatc gtaatagtat
    14941 cttgatcaag gcttgctaat aggtgtttag cagtcgggtg atccaggtag taatccgtaa
    15001 tgcggtcacg aatttcttgt tcgatgacac gtctaagtgg acgaactccc atcgcatgat
    15061 catagcccag atcaatcaaa cgctctttaa catcgtcagt cacctcaagg ctaatgcctt
    15121 ttttagcaag ggtttggttc acttctgtta gcattaaagc aacaatttct tgtaaatcct
    15181 ttttcgctaa atggttgaat tcgatgacac cgttgaagcg attcaagaat tctggtctaa
    15241 agtaaggtgc aatacgctcc atgatagcag gctcttgatc agcacgatct cctgcttgat
    15301 ggccaaaacc agcattagag gttgcgatga taaccgtatt tttgaaattg atcgtgttgc
    15361 cttgtccatc tgtcaatcgc ccatcatcaa gcacttgaag aagcagtgta atgacctgtg
    15421 ggtctgcttt ttcgatttca tcaagcaaga tgatagagta aggactgcga cggacacgtt
    15481 ctgtaagggt attttgatta tcatcatagc caacatagcc agctgttgtt ccgattaatt
    15541 tggaaacagc tgtgcggtca ctatattcag acatatctaa gcgaatgata gcgtcctttg
    15601 agccgaacat atcaagggct aactgcttag ccagctcggt cttaccaaca ccagttggac
    15661 caacaaagag gaaggagcca attgggcgat taccgtcatc aaagcctgcg cggttgcgtc
    15721 gaatcgcacg agcaacagcc tcaactgcac catcttgtcc gataacatgg cctttaagac
    15781 ggttactgat ttccttgagc ctttctaaat cactagcccc catatttgat actggaacac
    15841 cagttagacg ttcaacagat tctgcaatat cattaacagt ggcagtgacc ttttgccctt
    15901 cactgtgatg attgatttgc ttttggagct cctcaatgcg ggtcttagca gttaaggcct
    15961 tttcaaagtc ttcttctgca acagcctttt cctgtagctc cttttgctta gtgatttctg
    16021 cttcaagtga ttttagatca gtgacagggt gctgagctgc tagatgagca gcagtcatat
    16081 caacaaggtc aatggcttta tctggtaggc ttcgttgtgg aatatattgg atagcataat
    16141 caatagctgc cttcaagaca gagtctggta ggatcacatt gtggtgctgc tcgtagaggt
    16201 tgcgaatgcc cattaaaatg tggaaggtat cctctgctga aggagcatta accttaacct
    16261 cgttgaaacg acgagcaaga gcagcatttt ttagaatggt gttgcgatac tcatcttgag
    16321 ttgtggcacc aatcagggtc aactcaccgc gtgagagggc tggttttaga atatcagcta
    16381 agcccttaga gcctgagtct gaaccagctg accctgcacc aaggatttga tggatttcgt
    16441 caaagaagag aatgatattg ccagcctcct taacctcttt aaccatgttt tgaatgtttt
    16501 cttcaaagga gccacgatac tgtgtgccag cctcaaggcc agaaatatca attgagataa
    16561 tctctttatt tttgatggca gctggcacat caccgttgac aatagcctgg gctaggcctt
    16621 cgacaacagc agttttacca acaccagcgt caccgacaag aacagggtta ttcttggttc
    16681 gtcttgctag aatttctgcg gtcgcttgaa tctcatcgtt tcgtccgatc acaggatcta
    16741 acctgccttg ccgagcttct tcggtcaggt ttgttccgag cttggttaga atgccgtctt
    16801 ttttaaggct gctagcctgt ttttcttgtc cctcagctgc agctagctta ccggttttcc
    16861 ggtattcttg aaattcctct ggtgtcatct cacgtccatt gacaagatag cgacgatttt
    16921 cgctgcggta gccgccgatg tttcccatta actgattgaa aatatcgtcc atattttcaa
    16981 aggggtcttt tccataatag gttgccatat acacttacct cacttgtatt atatttacca
    17041 gtcattatga gctactggta taggtagaag gtgatcggtg ttggctcata cagagatcat
    17101 agagaggtct tatgagagtc tattgctcag gcttattact caccttctaa taatattata
    17161 tccaaaaggt cagtaaaggt caaacaaaaa gtatgaataa ttaaccttta taatcaggtg
    17221 cttatagccc ttgaaacatc agatgactat gccataagct gctggtgctt ttttgctagc
    17281 aaggctatct gtaaagaaga gacttttgtc aaaaatggtt ttactttttg ttctaaaggc
    17341 tttcatgata taataaaaga aaagcacaga ggtcaattat ggaacaaaca ttttttatgg
    17401 tgaagcctga tggtgtgaaa cgtggcttgg ttggagagat tctacgccgg attgagcgtc
    17461 gtggctttac ctttgatagg cttgaattgc gacaagcaac cccagaattg ctagctaagc
    17521 attatgacac cttaatcaat aagccctttt atccagagct agaggcctat atgacaagcg
    17581 gacctgtttt aatcggcatt atctccggta atcgtgtggt ctcttcctgg cgaaccatga
    17641 tgggggtaac caatcctaaa gacgctttac cggggactat tcgtggtgat tttgctcaag
    17701 cccctggtga tgatggcggc attttcaacg tggtgcatgg ttcggattcg agagattcag
    17761 ccaagcgaga aattgcgatc tggtttggac atagctgaca ttgggcttgg gcctattctt
    17821 ttaagaactg ataaagcaat tgcataaggg gttgataagc ccatcatcaa tagtagctca
    17881 gcattagaag ggtaacagcc ttgatgttgg gctatttttt tgcttgccta gggtctgtat
    17941 gcttgtcctg atgagcaggt agacaaagca gcataagttt aacaatcctt tgcggcagtg
    18001 atcaattgta gctctaacca tagcatcagc tatttgaaag ccttgaaaaa gaaagctaag
    18061 gctaacaagc tagtctaggt catttactac aagcgacttt tttcaattag ctgctcaagg
    18121 caagtattga aaaaagtcca tttttcatgt catttgtaat aatatggtat atttttaacg
    18181 aaaagtcgtt ttagttgaga aaatatacaa aaaaggctat gatatagtta ataaagttgt
    18241 tataccccct gtgtcttgta cactatgact tgtagagagt ttatcaaagg aggataagat
    18301 gaacaaacaa agcatgaccc atttttctaa gaagctgatg aagttagccc ttttaggttt
    18361 ggcattgcca ttaagcttgg tgtcggtggt agatactccg gttcttaacc aatccgaaaa
    18421 agctgtttat gccaatgatt ttggatctgg aaatcgagcc agtgattatg taccggcggc
    18481 taacgcttgg agctttgagg cttatccaga ttactacagt attttaggag ctagtcatct
    18541 taatcctgct gtctttccag agcctagtaa gatgtcatac agtcctttag acgagttggg
    18601 ccgcacacag gtcgcaagag gaacaataac ctatcacaat atcgtgatga attacaatgt
    18661 tcggcaacgc tttgctaaaa atcagaaccc ttcaggctgg attggtaacc ctagaaatgt
    18721 tcgctacact attgagtggc tagatggact atcctatcag ggagattttt ggaatcggag
    18781 tcatttgatt gcagatagcc ttggtggagc agccttacgt gtcaatgcta ttactggtac
    18841 aagaacacaa aatgttggcg gcagaaatca aagaggcggt atgcgctata ttgagcaaaa
    18901 ggtgcagcag tggattgagc agcatacaag cgcagttgtt tattacgaag cggtgccaat
    18961 ttaccaggca aatgagctag ttccaagagc tgttgttgtt tcagcattgt catcagacgg
    19021 aggtcttgac gaaaaggtca tggtctataa taccgccaac ggctatacca ttgattatgc
    19081 cactggcgca ttccgcagta actaggcttt tgtactaagc tgtagctgat caaggtctga
    19141 ctaagacaag ctcatcagca attggtatat aaaaagacgt ggcaacaaca tgttttaaat
    19201 gagttgtcat gtctttttag tgtcgtcagc ttttcacatt gtcttagaat gatcacacct
    19261 agctagccgc taaaagcatt ggtccaaaga aatgttaaga atagatagaa tgccttttaa
    19321 tcagtggtat gggactgcta gctaatataa tgcctgcagt tgagccaatt tctcatctag
    19381 gctaataact aacaagctat tgacttatcg tgttcattag aatgtcagct gttgtagttg
    19441 gtagtattcg aatacgatta agcgatagca ggccattagc agcacttgct agtccttcat
    19501 ttgttgtgac ccctaatttg taatgcagat cctcagcaat ctttaatgtg gtatcagtat
    19561 aacgacctgc tggataggca attgcaatgg tatcttggtg tagctctcta tctaggtatt
    19621 ctttagaatc tttcatttca gcggtttgac tagcagcgct tgcctgagat agatcagggt
    19681 ggttaaccgt atgatcttgg aaagacatgc ctgcctgctt catttccttc atctgatcca
    19741 atgtaagatt ggccgcatta cctgcctctg taaagccagt gataacgtta ttggtggcct
    19801 tgatgtcata ctttttcagg attggaaaag caacgttgta aaaatcaacc atgctatcat
    19861 caaaggttag ccagacaacc ttttcagcag gaagctcgtt agctgataag actcggtagg
    19921 cttcttcggg agataaaaag tagtagccgg cctccttcat tgcctttagc tggctttcaa
    19981 aaagatctgg agcaacgatg agattggcac ttgctgcctc ttctggtgcc ataacgtgaa
    20041 tagcatgata cattaagata ggaagcttaa cagggttttg ctgcttggtc cagctgacag
    20101 ctcctttttg ctgctgacta tttgtatggc tagcttcctt attagttgct tttttgctag
    20161 gcttgggagc tggtttttta tcagtttttg aaaataggct tattttgggg attgcctgcg
    20221 ataattgaga gatgcttatc tttgaatggc tcttgtaaag gtagacaata gctgataagc
    20281 ctatgataca ggcaagtagt agcatgagat taatcatttt gaagattttt cttttcttac
    20341 gccgtttgtt tctgttgttc atcacttgct ccttgtttat tgattagtct attgtaacat
    20401 ttttttaagt aagctgtctt tcgttaactt aattttttgc taacattcta ttagtgttat
    20461 gctttgtaaa acaagaccta gatttgctat aataagacag agtatttaag acagtcaaaa
    20521 aaaggaggat aggatgtcag ttaaggttgc attattaggc tttgggactg ttgctagtgg
    20581 cattcccttg ctattagaaa acaatagtag caagattcgt gcagtggtag gtgatgattt
    20641 ggtgattgca aaggttctgg ttagagatga gaccactaag aagcgtttgt tggatcaagg
    20701 ctattcctac caatttgtga cctccattga tgatattgtt gatgatgaga gcattgatat
    20761 ggtggtcgaa ttaatgggtc gtatcgagcc tgcaaagacc tttatctcgc gtgctctatc
    20821 agccggaaag cctgttgtga ctgctaataa ggatttgata gccttgtacg gaggagagct
    20881 ctcgactttg gcagctaagc atcaggtagc tttgtactac gaggctgctg ttgctggtgg
    20941 tattccaata ctaagagctt tggctgattc ctttgcctca gataagctga cgcgtctgct
    21001 cggtgtgctc aatggaacaa ctaatttcat gttaaccaag atgattgatg agggctggac
    21061 ctatgaaagg gccctgcaaa aagcgcagga gctgggctat gctgaaagtg atccgactaa
    21121 tgatgtgaaa gggatcgatg cagcttacaa ggttgctatt cttagtcagt ttgcttttgg
    21181 aatgaccatt gactttgagg ctattagcta ttcagggatt gataaggttc gagtagaaga
    21241 tgtgacagta gcgcagaagc tgggctatgt gatcaaatta gttggtctac ttgaagagac
    21301 ggcttctggg cttaacgcag aggtatcccc agtcttttta ccaaagacac acccgttggc
    21361 tgctgtagac ggtgtgatga atgctgttta tatcgagtca attggggttg ggcaggctat
    21421 gttttatggt ccaggtgccg gtcaaatgcc aacagctaca gctgttgtgg cagatatgat
    21481 tcagactgcc tgcaccttac gtgaccatac agtctcagtc tttaatcgtt ttgctacaaa
    21541 aactagacta gctaagtctg aggatattat gagtccctat tactttgcta ttcaagcaac
    21601 taataagttt ggtcagctac tagagctaac aaggctatgt gatgtttgtg gcattagagt
    21661 tgagcagctg ttatcagatg agatagatag tgacaggtta gactttgtga tgattactca
    21721 tgagatgagc aaaaaggagc ttgcttgctt tacagcgcta ctacaggatc atcaggattt
    21781 ccgtatgtta agtacattta agattttagg agattgacat gaagatacgc gtacctgcaa
    21841 cctcggctaa tttgggacct ggatttgact caatggggat tgctgtttca aaatacctag
    21901 aagttgacat tttagaagaa cgtgaccaat ggtttattga gcatgatttg ggtgatattc
    21961 caaatgatga tagcaactta cttatccaaa cagcccttag gctagcacca aatattccag
    22021 cacatcgtct aaagatgacg tctgatattc cattggcacg tggcttggga tcgtcctcct
    22081 cggtgattgt cgctggtatt gaattagcta atcagctagg gcatttaaac ctaacagacg
    22141 accgtaaatt ggccatagca actcgtattg aggggcaccc tgataatgta gctccagcga
    22201 tttttggtca attggtaatt gcttcacaga ttggtaagga cgtggattac atcattgcgc
    22261 cttttcctga cctttctttg gtttgtttta ttcctgatta tgagctgaaa acctctgatt
    22321 ccagagatgt attgcccaag cagctatcgt ataagcaggc agtggctgct tcctcagttg
    22381 ctaatcttgc tatagctgcg ctattgaccg gtaatttgaa aaaggccggt cgggcgattg
    22441 aaaatgacca attccacgaa atctaccggc aaagattagt cagagagttc cagccgatta
    22501 agcgagctgc agcagctaat ggtgcttatg caacctactt atccggtgca gggcctgcta
    22561 ttatggttat gtgtcccaat aagaaaaaaa tggcgattta tgaggccatc gagcagctag
    22621 gtctaattgg tcagttggtg tctctagagc tggatcgtca ggggctgtgt cttgtctaga
    22681 ctggcaaggt actggtatgc ttgcctagta ggcttattgt tgatatcaga tggacttaaa
    22741 gcttagtcat tcaaatacat caaaaaagtg aggcttgatc gttttatcgg ctttcacttt
    22801 tttcttgata tgttatacta gagtagactt tgtgaggtgt gtgatgaatt atcaagaaac
    22861 attagactgg attcatggtc aggaaagatt tgggatcaag ccaggtgtaa aacgcatgcg
    22921 ttgggtgctt gagcagctag gtaatcctca agataggatt agaggaatcc atgtggtcgg
    22981 cacaaatggt aagggatcga cggtcaatga cctacagcat atttttacta gagcaggcta
    23041 tgaggttgga acctttacct cgccttatat catggatttt aaggaacgta tctgtctcaa
    23101 tggtgagatg atctcagaga ctgaccttgt taaggctgct aattgtattc gtccactaac
    23161 ggatcgcctt atcagtgaga caagtttggg tcctgcaaca gtctttgagc tgatcactct
    23221 gatcatgttt ctttattttg gtgagagtca cccggttgat attgctatta tcgaggcagg
    23281 attagggggg ctttatgact ccactaatgt gtttcaggcg atggctgtgg tttgcccgtc
    23341 tattggtctt gatcatcaag ctattttagg tgatacctat gctgacattg cctatcaaaa
    23401 agccggtgtg ctaaagggtg gtgaagacct tatttttgcc attgataaca aagaggccag
    23461 acaggttttt ctaaaaaaag cagagcagct tggcgtgcct atttgggaat ggcgtcgaca
    23521 gttcaacatg ctacagggtg aaggtggtta tcaatttaac agtcagcttg gtcagctgtc
    23581 tcatctagtg cttgcaatgc ctggtcagca tcaggtagcc aatgcaggcc tagccactat
    23641 gacaagcttg atattacagg atcggtaccc aaaggtaact gagtctgtta ttagagaggc
    23701 tctggcaagc agcttttggt tgggacgaac agaattgttg gcacccaacc tgatgattga
    23761 tggtgctcat aataatgaaa gcattgccgc cctgattgat gtgatatcat cagactatca
    23821 ggataagcag attcatattc tatttggtgc cattgatacc aagcctgtct cagatatgct
    23881 gcagagtctg gagcgtcttg gagatgtgca agtaacaagc tttcactatc ccaatgccta
    23941 tcctttggag gcttatccag ataggctaac aaaagtagca gattttagag catttttaga
    24001 ccggcttgag caagcagctg ctgatgattt tttcctgatt acaggctctc tttacttcat
    24061 ctcagaggtc aggcagtatt ggaaaaaggt attaagcaag taatgctttc tcacatcaac
    24121 tcatcaaaca agattaatca actaaaaagg ggaaaaccat tgccaatcaa tcaaaaaaaa
    24181 gcagaagccg ctatctatca attattagaa gctatcggtg aggatccaaa ccgagaaggg
    24241 ctacgagata ccccaaagcg tgttgccaag atgtatctag aaatgctctc agggctggaa
    24301 caggacgcta aggatgaatt tacagctgtt tttacagagc atcacgacga tttggtgatt
    24361 gttaaggata ttagctttta ttccatgtgt gagcaccatc tggtgccatt ttatggtaag
    24421 gcgcatattg cttatttgcc tagtgatggg cgtgtgacag gcttgagtaa gctggcaagg
    24481 gcagttgagg tgacgagcaa aagacctcag ctgcaggagc gtttgacagc tcagattgct
    24541 aatgctcttg ttgatgcctt gcagcccaaa ggggtttttg ttatggtaga agcagagcat
    24601 atgtgcatga ccatgcgagg tgtcaaaaag ccaggcagta agaccattac gacaactgct
    24661 agagggattt acaaggatag tagagacgac aggcgtgagg ttatgcaatt aatcatggag
    24721 ggctagggta tttatgacta ttggacatta ttcagccgct ggtgaggcag ctattatggg
    24781 gattttaaat gtgactccgg attcgttttc agatggtggc tcctatacta gtgttaatca
    24841 ggccttggca caggccgaaa aaatgctgtc agaaggagcg actgtcattg atattggagg
    24901 cgagtcaaca cgaccgggct gccaatttgt gccggcagaa gaagagattg cacgcgttgt
    24961 tccaatcata aaggccatta aaaaacggta tgatgtcctt attagcattg atacctacaa
    25021 gacagaaact gctagagcgg cccttgaagc aggagcagat atgctcaatg atgtctgggc
    25081 aggactatat gacggtcaaa tgctaagtct agccgccgaa tacgacgttc ccattatatt
    25141 aatgcataat caaaccaaag aggcttatgc tgatgttaca aaagaggttt gcagcttttt
    25201 acaggctaga gcagctgcag ccctcaaagc aggtgtcaaa aaagaacata tctggcttga
    25261 tccaggattt ggctttgcta aaaatgttga gcaaaatata gccttattaa aagggctaaa
    25321 tgaggtttgc cagttgggct atcctgttct ttttgggatt tccagaaagc gtgttgtaga
    25381 cgccctactt ggtggcggca ctaaagccaa ggatcgtgac ggggctactg ccgccctatc
    25441 agcctacgct attaataagg ggtgtcaaat ggtgcgcgtg cataatgtcg gtgctaacag
    25501 ggatattgtc tctgtattga gtcaattaag gtgagaaatg atggataaaa tcagattaga
    25561 ggcttgtcgc ttttatggtt atcatggtgc ctttaaggag gagcaggtct taggtcaaat
    25621 ttttgtagtg gatttagaat tatcagttga cttgatggct gcctctcttt cagactgcct
    25681 agaggatact gttcattatg gtttagtttt tgaaacagtc cgtcaaattg ttgaggaaaa
    25741 gacctttacg cttatcgaac gtttggctgg tgccatttgt caagagctat ttgcccagtt
    25801 tttgcctatt aaagcgatta aaatcgctat taaaaaagaa aatccaccga ttgcaggcca
    25861 ttatcaagct gtcggtattg aattggagag aaagagatga cacttgttta tttaggcttg
    25921 ggaactaata tgggagatag ggcaggctac ctacaggcag cagttaatgc cctatctaag
    25981 ctgccagaga ctgagttact gagacaatcc tctatctatc aaacagcagc ctggggaaaa
    26041 acagatcaaa atgccttttt gaatatggct tgccagctag atactaggct gacatcagaa
    26101 gctcttttgg cagctacgca ggctatcgag caggctctgg gacgagttcg tcatgaaaaa
    26161 tggggcccaa ggacaattga tattgacctc ttgctgtttg gtgatgagcc gtatcaatca
    26221 gagaccttgg ttattcctca cccttacatg acacaaagag cctttgtttt gattccttta
    26281 ttagagattg cacccgatgt gaccttacct ggtagccaga aaagcctgag gtcttacctt
    26341 gatgctttag agcaatcaga tgtagccttg tggtcacatg agtattcaaa taagttttct
    26401 taaactgtcg ttatttttac taaaatttga tataatagtg ctactctttg ctgatttttt
    26461 gtcttatatt aagaaatgat tgaagaaaga agaagattat gatagctgaa cttgaaggca
    26521 ttgatattcg agagaatgaa gccttaaaac attacaccta tacccaagta ggcggtccag
    26581 cagatttctt ggcttttcct agaaatcatt acgaactatc ccgtattgtt gattatgcca
    26641 atcataatca tattccttgg atggtccttg gaaatgccag taatctcatt gttcgagacg
    26701 gtggtattcg tggctttgtt atcatgtttg ataagctcaa cgccgtccgc cttaatggtt
    26761 ataccttgga ggcagaggca ggcgctaacc tcattgaaac aacaaaagtt gccaaatttc
    26821 atagcttaac aggctttgaa tttgcttgtg gcattcctgg aagcataggg ggtgctgttt
    26881 ttatgaatgc aggtgcttat ggtggagaga ttgctcatat ttttttgtcg gccaaggtct
    26941 tgacaccaga agggaaaata aaaaagatct cagccagaga gatggccttt ggctatcgtc
    27001 actctgtcat tcaagaaact ggtgatattg tgatttcagc caagtttgct ttaaaaccgg
    27061 gtaatcatga cagtatttgt caggagatga atcgcctcaa ccaccttcga aagctcaagc
    27121 agcccttaga atttccctct tgtgggtccg tttttaagcg tcctcctggg cattttgcag
    27181 ggcaattgat tatggacgct aacctaaaag ggcatcgtgt tggcggtgtt gaggtctcta
    27241 aaaagcatgc aggctttatg attaatgttg ctgatggctc tgccaaggat tatgaggact
    27301 taattgctca tgtcattagg acagttgagc aggcatctgg cgttaggctt gagccggagg
    27361 ttcgtattat tggtgaaagc ctttaatgat tgtgttatca aaaaagaaaa attgtggagg
    27421 atttatgaca attgactaag ccaattatca catttgacaa tgtctcaaag acatttgagg
    27481 acagcgggac acaggtccta aagaacatta attttgagct tgaggaggga aaattttaca
    27541 ccctgcttgg tgcctcagga tctgggaaat caaccatttt aaatattatg gctgggctgc
    27601 ttgatgcgac cagtggtgat atttatttag atggtgagcg tatcaatgat ttgccgacca
    27661 ataagcgtga tattcacact gtttttcaga attatgcttt gtttcctcat atgacggttt
    27721 ttgagaacgt tgcctttgct ttaaagctga aaaaggttga caaacaggag atagcaagac
    27781 gtgtcaagga aaccttaaaa atggttcagc tggagggcta cgaaaagcga tccattcaaa
    27841 agctttccgg tggtcagcgt cagcgtgtag cgattgctcg tgcgattatc aatcagcctc
    27901 gtcttgtcct attagatgag ccactttctg cccttgattt gaaattgaga acagaaatgc
    27961 agtatgagct gcgtgagctg cagcagcgac tgggcattac ctttgttttt gttacccatg
    28021 atcaggaaga agcactagcg atgagtgatt ggatttttgt catgaatgat ggtgaaattg
    28081 tgcaatcagg cacacctgta gatatttacg atgagccgat taatcatttt gtagctagct
    28141 ttattggtga atcaaacatc atcaatggta cgatgattaa agactatctg gtttccttta
    28201 acgggaaaga atttgagtca gttgatggtg gtatgcgacc caatgagcca gttgaggtgg
    28261 ttattcgacc ggaggattta caaatcaccc tgccagagga aggaaagctt caggtaaagg
    28321 tagatacaca gctctttcgt ggtgttcact atgaaatcat tgcctatgat gatttaggca
    28381 acgaatggat gattcactca acccgcaagg ccattgaagg agaagtgatt ggtttagatt
    28441 tcacaccaga ggatattcat attatgcgcc tcaatgaaac agaagaagaa tttgatgctc
    28501 gtatcgaaga atacgttgaa atcgatgagc atgcggatgg cttaatcaat gctattgagg
    28561 aggagcgcaa tgaagaaaac ctctagcctc tttgcagttc cctatttttt atggattgtc
    28621 ctctttgtta tggcaccggt tgcccttttg ctttatcaat ccttttttga catcgaagga
    28681 cgattgacac tagccaatta cgagactttt tttagctcat ggacttacct gagaatgggc
    28741 ttaaactcta tcttatatgc tggtatcgtt accttggtga cctttttgat ttcatatccc
    28801 acagctttat tgttaacgcg tttaaagcac aagcagctgt ggttaatgct tattatttta
    28861 ccaacctggg tcaatctgct cctcaaggct tatgctttta tggggatttt tgggcagcag
    28921 ggtggtatca atagcttttt aacctttatg ggcttaggac cacagcaaat tctgtttact
    28981 gatttttcgt ttatttttgt ggcctcttat attgagctgc cctttatgat tttgcctatt
    29041 tttaatgctt tagatgatat tgatgataat attatcaatg ccagtaagga cctgggtgcc
    29101 aatgactacc agaccttttc aagggttatc tttcctttgt cgctaaacgg tgttagagca
    29161 ggggttcagt ctgtttttat tcccagcttg agtctcttta tgcttacgcg tctcatcggt
    29221 ggaaatcgtg tgattacgct ggggacagct attgaacagc atttcctaac aacagaaaac
    29281 tggggcatgg gctcaaccat aggtgttgtc ctaattatcg cgatgattgt gattatgtgg
    29341 ctaacaaagg agaaaagtaa atgaaaaaat ttgccaatct ttacttagcg tgtgttttta
    29401 ttttgctcta tattccaatc ttttacttga ttgtttattc ttttaacaag ggtggagaca
    29461 tgaatggctt ttctggcttg acgctagagc attataagac catgtttgat gatagtcgct
    29521 tgatggcgat tttattgcag acctttgtgt tagcctttac aagtgccttg cttgcaacca
    29581 ttatcgggac ctttggggcg atttttattc atcagagtaa aaagaagtac caaaatgcga
    29641 tactgtctgc aaataatgtg ttgatggttt cccctgatgt gatgataggt gcctctttct
    29701 tgattctctt tacgtccttg aaatttcaat taggaatcct ctcggttttg atgagtcata
    29761 ttgctttttc cattccgatt gtggtcttaa tggtgcttcc tcggttgaag gaaatgaatc
    29821 aagatatgat taatgcagct tatgatctag gagcaaatca ctttcaaatg ctaaaggagg
    29881 ttatgcttcc ttatctgaca ccgggcatta tcgcaggcta ctttatggcc tttacttatt
    29941 ccttagatga ttttgcggtg accttttttc taacaggaaa tggctttaca accctgtctg
    30001 ttgagatcta ttcgcgtgct cgaaggggta tttcattaga tatcaatgcc ttatcaacga
    30061 ttgtcttttt gttctcaatt ctattagtca ttggctatta ttacatttca caggacaagg
    30121 aggaaaagca tgcgtaagct atactctttt ttagcgggaa ttatcggggt tatcttgctg
    30181 cttgcgaccc tgtcctttat tttgcagaaa aaaacgagct ctgctagtca atctgataag
    30241 ctggtgattt ataactgggg tgattacatt gatcccgctt tgctgaaaaa attcactaag
    30301 gaaaccggta tcgaggttca gtatgagacc tttgattcca atgaagccat gtacaccaag
    30361 atcaaacagg gtggaacgac ctatgacatt gctgttccga gtgattacac gattgacaag
    30421 atgattaagg aaaagcttct tgttaagcta gataagtcca agcttgttgg tctagataac
    30481 attggtcagg agtttttagg aaaaagcttt gatccgcaca atgattattc cattccttat
    30541 ttttggggaa cggtaggcat tgtctataat gaccagctgg tggataaggc tcctatgcat
    30601 tgggaggatt tatggcggcc agaataccaa aatagtatca tgctagttga tggtgctcgt
    30661 gagattttag gtgttggatt gaccacattt ggctatagcg ttaactcaaa gcacctaaag
    30721 cagcttgaag cagctgaaaa aaaactacag gccttaaccc ctaatgtaaa agcaatcgtc
    30781 gctgacgaga tgaaggggta tatgattcag ggtgacgctg ctattggtgt taccttctca
    30841 ggagaggcta gcgaaatgct ggacaataac gaccatctac actatgttgt accatcagag
    30901 ggctcaaacc tttggtttga taatctggtg cttcccaaaa caatgaagca tgaaaatgaa
    30961 gcctatgcct ttatcaactt tatcatgaag ccggaaaatg cagcacaaaa tgctgaatat
    31021 atcggctatg ccactcccaa tacaaaagcg aaggctttat tgccagatga tattaaaaat
    31081 gacccagcct tttacccaac tgacgagacc gtaaagaaat tagaggttta tgataattta
    31141 ggctctaaat ggcttggtat ttacaacgac ctttacctac aatttaagat gtatcgaaaa
    31201 taggtcatgc aagattgaag gagctattca ttggaaagct tcttcagtct tttttagctt
    31261 ggtctggtct caataatctc atgagattaa aaagaactag aatcttgctt tcgtctttga
    31321 tacaatagta gtggtttatt aaaatgaaag agatgacaaa atggaaaatc ataaaaacga
    31381 gtttaccttt tccaaacatt caatcatagc ctacgtttgg cgtggcattt tagtcgggat
    31441 aattgctgga gctattgtca gtttgtttcg cttattgatt gagatggtta gtgaggctgt
    31501 tgttggctat tatcaccaag ctcacagcaa tcgcatgctc cttgttccga tagcaggctt
    31561 tagcttatta gctgtttttt tagttggtct tttggtcaag tctgacgcca acattaaagg
    31621 ctctggtatt ccacacgtcg aaggggagct aaagggcttg atgtcaccca attggtggag
    31681 tgtgctttgg aaaaaatacc ttggtggaac aattgccatt tctatgggct taatgcttgg
    31741 aagagaaggc ccttctatac aattaggggc tatgtcagct aaaggcttag ctaagtacct
    31801 gaaatctagt cgtctagaaa aacgtgtctt gatcgctagt ggagcagctg ctggcttatc
    31861 agctgctttt aatgcgccta ttgcaggact gctttttgtt gttgaggaga tttaccacca
    31921 tttttcaaga ttagtgtgga tcactgcctt ggttgcaagc cttgttgcga actttatttc
    31981 gttgaatatt tttggcctta gacctgtttt ggccatgcct aaggccatgc cctttcttgc
    32041 cttacatcaa tattggctgc tcttaatctt aggccttgtg cttggctgtc tgggctttct
    32101 ttatgaagag gtcattttac attttcatag ggtttatgat tttcttggaa agagcttgcg
    32161 cctagcgccg cattttcatg ggctgattgt tgttgctatt atcctgctga ttggctatta
    32221 tttgccacag ctattgggcg gaggtcatgg tttgattatg tccttgtcag agcaaaagct
    32281 accactgttg actgttcttg cttacttctt tattcgattt ttagggagta tgtttagcta
    32341 tggcagtggc ctgcctggag gaattttttt gcctattcta accttaggtg ccttgtccgg
    32401 aactattttt ggattgattc ttcagcaaat aggactgtta gatcgccaga tgattcctct
    32461 ctttttagta ttgggaatgg caggctactt tgctgctgta tcaaaggcac ccttgacagg
    32521 aatgatctta gtgactgaaa tggtagggga tctgaagccc ttaatggcca ttgctgttgt
    32581 gaccttcgtg gcctacttgg tgatggattt gttaaatggt cagcctatct atgaagcaat
    32641 gctagagaaa atggctatca aacacccaac agatctagtg gagccgaccc tgatcgaatt
    32701 acctgtaagt gagaaaattg caggcagata tgtccgagac ctgaagctac ctaaaaacgt
    32761 tttaattaca acgcagctcc accataagaa atcacaggtc gtctcaggtg atacgctatt
    32821 gatttcaggt gctacgatct ttttggtggt caatgaagct gatacaggct ttgttcgaga
    32881 ggtcttgatg tagagcaagg tcggttaagc agtcagcagt agctgtgcta ccgatcaaag
    32941 aagcagatca gtgctttttc tcatctgatg aaaggtattg atttgctttt tttgtgttat
    33001 taaacctttg ttagcaagag ccatagcctt agcagtcgta tctgatgaat acctgctgtc
    33061 tttttgttat acttaagtat caatcaaagg agctttatat gctagaagtt atttcaaaag
    33121 agctgcgcca ttaccaaaag aataagcttg ccgcctatca aaaaaagaac caaggcatag
    33181 aagctggtgg aattgttttt gctggcgatt cgttaatcga atttttcccg ttgaaaaaat
    33241 atttcaaaca ggtctcaacc atttataatc gcggaattgc agggatagac agtcagtggt
    33301 tgctagagca tattgacagt catgtgaatg atctggagcc cagtcatgtg tttatcctga
    33361 ttggctgtaa tgatattggg cttggctttg atcaatcgca tatcgtatcg accattgttg
    33421 atcttattag tcgtattcgc agtcagtcta tttatactag gattagcctt ctgtccttat
    33481 tgccggtttc tgaaaatccc gcctatcagg cgactgtcaa gctaaggaca aatagggcta
    33541 ttgatgagat taatcaagca ttagcaatga taccagcgat tgaatttatt gatcttaacg
    33601 cctgcttaaa ggacgagact ggtggcttag cagctgctta tacggtagat ggcattcatc
    33661 ttaatgccct tggctatgaa cacttagctc aagctattag tccctatcta tgaaaggtaa
    33721 aggctggagc tgctaatttg taagggatct ttaaaaaaca agcactgatg aatcatcatt
    33781 gaaacccttc agagtgccga taggctgcac aatcaaagaa gcattaggtt tgtctatgac
    33841 gcccttgtgt taagctggct tttaggttta tactgcgaga aaatcagtca ttgggctggg
    33901 agtctcaaag cttagctgtg gtaattaaat gcgagctcct gctagcttgt gctgatcaag
    33961 cagtatagca aggagggact gaacttttag tctcagataa tattagactt tttatcctat
    34021 attaaacgat ttagtgtata ataaacagga aggagttaaa atgaaatttg aaaaaaaaca
    34081 agtcttttat gttgtgcttg cctttgtgct ttgttatgct attcaagcta attgggataa
    34141 tggggctaat attgtcacaa ccgtttataa gacaagcctg ccctttcttt atggagcagc
    34201 agtcgcctat attgttaata ttgtcatgag tgcctatgaa agagcttata cttataccct
    34261 aaaacccttt ccttttgcca tgaaggctag aagagggctc tgtatgcttt tggcatattt
    34321 tacctttatc agcttgatcg tatggattat ttctattgta atccctgatt tgattgcaag
    34381 cattagctcg ttaacgcaat ttgatacaag agctatcaag gaggtcatca gtgatttagg
    34441 tcacaataag ctgattgcac gtgccattaa ttacattggt ggagatgcta agctgacaga
    34501 aacaattacc aattatagcc agcagctgct caagcaattt ataggtgttc taaccggtat
    34561 tttgacatcg gttacagcag ttgcctcagc cattatcaat gtggttatca gctttgtctt
    34621 ttccctgtat gtgcttgcta gcaaggaaga gctttgtcag caggcaacta ccttaattga
    34681 cacctatact ggtaaatacg caaaggccat tcattattta gtgggtttgc tgcatagtcg
    34741 ttttcgtggc ttctttgtga gtcagacgct tgaagcaatg attttaggct ccttgactgc
    34801 cattggcatg tttatcctgc aattaccctt tgcaggaact attggagtct tggttgcttt
    34861 tactgccttg atccctgttg ttggtgcttc aatcggtgct gcgataggct ttgttttgat
    34921 tatgactcag tcaatgtcgc aggcagtcgt ctttattgtc tttcttgtta tactacagca
    34981 aatcgagggg aattttattt atcccagagt ggttggtggg tctatcgggt taccagctat
    35041 gtgggtctta atggcaatca ccattggtgc tgctctcaaa ggcattgttg gtatgatcgt
    35101 tgcagtgcca ttagcggcaa cgctttatca agtggtaaag gatcacattc ataaaaagca
    35161 ggccttacaa aatcgtcagt ccagctaatt aacagcatca gatcaaggaa aacgtctatt
    35221 acaagaccga tttcttggtc ttttatgctg tctgattgac tgcgtatggc cttattttta
    35281 tgctgtggta atgaaaaaag ccgtcttatt tatcgaatat cattagtgga ggtaataaga
    35341 tgtattccat caaaactgat cataaattaa tgcctagaga gcgtttgatt cgactgggtc
    35401 cagaaaagct aagcaatcaa gagcaactag cgatcctact taggacaggt aacaaggaaa
    35461 agcatgtctt agagttgtct gcttatttat tgtcaagctt agatagtcta gctgacttga
    35521 agaaattttc tttacaagaa ctacagcgct tatccgggat aggaaaggtc aaggctattg
    35581 agattaaggc catgctggag ctggcagacc gtattcagat agcgggacaa gcagtagcag
    35641 atcctgtctt atctagtgct caggtggctg aaaagatgat gattgaatta ggagacaagc
    35701 agcaggagca tttagtcgct atttatctcg atagtcaaaa taaaatcatt gaagaaaaga
    35761 cgatatttat aggaaccgtc agaaaatcaa ttgcagagcc tagagaaatt ctttattatg
    35821 cgtgtaaaaa tatggcgact agccttattg ttgttcacaa tcatccctca ggcctgacca
    35881 agccaagcgc aaatgactat cacttcacag aaaaaataaa acgatcatgt gattatttag
    35941 gacttatctg cctagatcac attatcgtta gtaagtatga ctactatagc tttcgggaaa
    36001 aatcagattt attttgagtt agaaactatg gataaaccaa tcaaagagcc ttaggtcttc
    36061 ttctctaata gcctgaagca gctctgggtg ccactggaca ccgagaaagg gaatatcagg
    36121 attgcaggag ataacagcct cgatggtgcc atcgttagga tcccttgcaa tcactcttaa
    36181 gtcctctgcg acctgcttta ggctctggtg gtgaaatgaa ttaatcagcg ctcttggacc
    36241 atagataggg tacaaaggtg aagtcttttc gatcactatc tcctgtgata aacagtcaga
    36301 ggcagtcttt tgccaatggc cctcaatgtg ctggtttaga ctgccaccta gagcaacatt
    36361 tattaactgc ataccgcgac aaatccctaa aattggtttt ttctgcgcta gggcttcttt
    36421 aatgatggct agctcaaaga tgtcacgctg gggtgaaaaa tcaccatcaa gtgcagctct
    36481 tttttcatga taatatttag gatcaacatg ctgaccacca ataagaatga ttttatcaac
    36541 cattgcgaca taggatttgg cagccgcctc atccccaatc ggaagaagta agggtaggcc
    36601 accagatctt gtcacagcct cgatgaagct tgttggagca taggagcaag gcaggttatc
    36661 tagagccttg gtcccccttt ggttagcagt tatcccaata attgttttag acacgacctt
    36721 ctccattaat caagatgatt ttggttcata aagtatagca aggtttgcaa ctcgctggtc
    36781 aaatcaacag attggacgat cacacctttt ggaacctgta agtgaagtgg agcaaagctt
    36841 aaaataccgc gaatgccagc ttcaatcagt tgatctgcaa cctcttgagc atagatgctt
    36901 gggactgtta gaatagccgt ttcaatgcct gaattatcca ggtgctcctt aatggtagaa
    36961 atgccataaa taggaatatc atcaggcgtt ttggtgccga ccataggatt atcatcagtg
    37021 tcaaatccca taacaatctg cattttgttt cgatcgtgga agcggtagtg aagaagtgca
    37081 cgaccaatat tgccgcagcc aactaaaatc acatgcgttg ttgagtgatc atttagcaaa
    37141 tctgcaaaaa aattcattaa ttttgtgaca tcatagccaa atccacgtcg gcctaattca
    37201 ccaaagtaag aaaaatcacg tcgaacagtt gcagaatcaa ttcccatagc atcagcaatc
    37261 tgttttgagc ttgccttttc aacctgatca gcataaaagc gtttaaaaat acgataatag
    37321 agtgataagc gttttgcagt cgcttttgga atagatttat caataaccac ttttgtagct
    37381 ccttctattg ttattttaat gttatctatc accattgtag cagatagatt gtgaaatatg
    37441 caactatttg accattcttt ttgtgttttt cgttataaaa tgacttgaca gcacaagcat
    37501 tggtattttt caaacccagt cacctcgagt ataaaaaagc agacaatgaa gcacttgccc
    37561 tttaggtcag ctgcgatggc tgggcttgtc ttgttaaagg caaatgtact gtcattgtct
    37621 gatatttctc tgagattaga agagctcttg tgtgcttagc attctttttt aatgaaaata
    37681 tcacgctcaa caaggctatc cattaaaaag taaaacttgt cctgtagtat gctatgctct
    37741 tcagatttaa aaatgttcac cagtcttaga ccggattggt ctgttatagc tagcttaaag
    37801 ccatctaaat ctttattaat cgtaattttt aaagggaagc cctcacccga attagggact
    37861 ttttccagta gtcgtgttaa ctgatagtga ccaatcttgg tctgactaaa ggttgtgtct
    37921 cttagggtgt attttttaat ctttgggcta atcctgtagc tgtatttgca gtctttaagg
    37981 gcaatttctt tttcaaatgc catatgatcc tcctaaaata tttttgagct gggttgctag
    38041 tgcgataacg tctttttgag tattttgctc tgaaaagcta actcgaatag cttctgtgag
    38101 acgatgggac tgcttgccga aataagctgc caaaacgtga cttggctcaa cagcaccagc
    38161 tgtacaagca gagcctgacg acacagcaaa gcctgctaaa tcaagctgag tcagtaatac
    38221 atgattttgg taaccaggaa agccgatatt aatgatatag ggaagatgac actcattatg
    38281 attgagctga taagaaatac cttctaattc actaagcaag agctgtgata gctctttagc
    38341 atgctggtaa tgctgtggca gccttgagac agcctcatct aatgcttggg tcatgccgac
    38401 gatattaatc aggctttcag tgccggctct ttgtttgttt tcttgattgc cgccatgtaa
    38461 gaggggggcc aactttaagc ctttattgta taaaaaacca gtcccctttg gtccatgaaa
    38521 cttatgggca gaggcagaga gcaaatcaat ccccaaatct gccggctgta ttgggacctt
    38581 gccaatagct tggacagcat caacatgaaa gacagcctga tgctgcttta gcatgctacc
    38641 aacagcctga ataggcagca aatctcccgt ttcgttgtta gcaaacatca tgctgactaa
    38701 gattgtatcc tctcttaagg cagcttggag ctgatttaga tcaatgattc catttttagc
    38761 ctcaaggtag gtcacctcaa agccaaatcg ttcttccaga taggccattg tgcttaacac
    38821 ggaatgatgc tcaatagcag ttgtaatcaa gtgtttgcct ttttcctgat gagctaaggc
    38881 atagcccttg atagcagtat tgttactttc agtacctcct gaggtaaaga taatgtggtt
    38941 ttctgcagct cctaggcagt tggcaatagc ttttcggcac tctcttaatt gtttgtttgc
    39001 ctgccgccca taagcatgaa tactagatgg gttaccaaaa tcatcagcca tagcttcagt
    39061 catcgccttg atagcagcct gactaagcga tgttgtagca gcattatcaa aataaatcat
    39121 gattagttag tgctttcagg tttgtaagaa aacagtggac ttagtggttt tctttcgtga
    39181 atgcgaatga tagcctctgc aattaaatca ctggcactaa gataggttac tgttttaggg
    39241 atacgatttt tagtcttgac agagtccgtg acaatgatct ctttgattgg agcagtctct
    39301 aaaatatcag ctgcacctcc tgcaaaaatc ccatgactag ccactgcata aatgtcagtt
    39361 gcgcctgcac attctaggat cttagctgcc tctgcaaagg tttttcctgt gttgagaatg
    39421 tcatcaatca agatagcctt cttgccagca acatcaccaa tcacatagcc ttcttcgcgc
    39481 tcagcatcgt cttgtgcata atcgataatg gcaattggag agttaagata ctctgctaag
    39541 cttctagcac gcttgatacc agaattttta gggctgacaa taaccgtatc aggtcctgag
    39601 aggcccagtg gataatagtg ctttgcaaaa agaggcactg taaataaatt atcaactgga
    39661 atgtcaaaaa agccttggac ctgaaccgca tgcaaatcaa gggttacaac gcgatcaatc
    39721 cctgctttgg tcagcatgtt tgcgaccagc tttgctgtaa taggctcgcg agactttgca
    39781 acacgatcct gacgcgaata accaaaatat ggcaaaacaa tattgactgt attagcactt
    39841 gcacgcttac aagcatcaat catgatgagc agctcccata ggttatcgtt gacaggaaag
    39901 cttgttgatt gaatgatata aatatcatca ccacgaactg tttcttcaat gttaatcatg
    39961 atctcaccat cagaaaattg acgagatgag acctttccaa gcggaatacc agcagcctta
    40021 gaaatttttt cagcgattgc gagatttgaa gtgagtgaga acagcttgat ttgcttgtca
    40081 gcatatcgtt cagtcatgat aaaattagct ccttacatta cattaacgat agaataacag
    40141 gttaacagtt attcaagatt acaaatagac agtactattt taacaaaaaa acagaaaaat
    40201 ttcagtcttt ctgttgattt tctgtcctct cctaggattt tttaagggtc ttgctaaagc
    40261 gagcgacctt gcttttggaa tatttaaagg tgatctgatg ctgggctaaa aagtggtcaa
    40321 aatcaacctt tcctcttaca ggatcagtca cctctagctc aagctcatag tctttgatac
    40381 cagcatattg attataatcc agcgctagct tgccaatagg agtatctgcc tctcgacgaa
    40441 tggtagtcag gtttccgaag gtttttatag cagataggtc aacgtcaaga gtgctgataa
    40501 tatcaaggat agctgatttt ggtagctgtc ctgtctgaat gatagctttt gcttgggtgt
    40561 catcaagctc taaattgtac tcgcgattac caaccttttc agggactttt aaggttaatt
    40621 cagcaggagc agcaacaaag gtgcgaatgc gaagtgacat tttatgagcc ttgagatcaa
    40681 aatgatcagt atcaatgtaa taatttgtct gggtaactgg tgggacatga gtcatttgag
    40741 agaggaggcg attatattcg tcctttgtca gtaaggtctt gtattcgatt tctaggttag
    40801 tcatgcgaac gttcctttta actatatttt atgctataat aaattgttat cttaatttta
    40861 tattaatatc cgaggtttga caagaaagga gagaaaggat ggctttagat tgggaagaat
    40921 ttttggatcc ttatatacaa acggttggcg aattgaaaat taagctgcgc ggtatccgaa
    40981 agcagtttcg caagcaaaac cgttattctc ctattgagtt tgtgactgga cgtgtcaagt
    41041 cggttgagag catcaaggaa aaaatggcct tgcgtggtgt cttggaagaa aatatcgctc
    41101 aagatattca agacatcgct gggcttagga ttatggtgca gtttgtggac gatattgagg
    41161 acgttttgtc cttgcttaga caaagacagg acatgacaat tgtttatgag cgagactaca
    41221 ttagaaacat gaaatctagt ggttatcgct cgtatcatgt tgtcgttgag tatcctgttg
    41281 ataccattga gggtcaaaaa aaagtattag cagaaattca aatccgtact ttagcaatga
    41341 atttttgggc aaccattgag cattccttga actacaagta cggtggtgat tttccagaag
    41401 aaataaaaaa acgattagag gttacagcaa aaattgcttt ggagcttgat gaagaaatgc
    41461 gaaaaattcg tgaagacatt cgtgaagcac aattgttatt tgatcctgta acacgtcatt
    41521 tgagtgatgg tgtaggaaat agtgatgaca cagatgaatt atacagataa agtaaagcgc
    41581 gttgctatca ttgcaaacgg caaatatcag agtaagcgcc ttgcctcaaa gctttttggc
    41641 gtctttaagg acgatccgag tttttaccta tccaaaaaaa atccggatat tgtgatttca
    41701 attggcggag atggcatgct tctatcagcc tttcatatgt acgaaaaaga attagacagg
    41761 gtgcgatttg taggcattca cactggacac cttggttttt acactgatta tcgtgatttt
    41821 gaggttgatc aattgatagc caatcttaga agagacaccg gtgagcaaat ttcttaccct
    41881 attttaaagg tagttattac gcttgatgac ggtcgcctgt ttaaggctag ggctctcaat
    41941 gaagcaacta ttaagcgtat cgagaaaacg atggttgcag atattatcat taacaatgtc
    42001 aagtttgaaa gctttcgtgg tgatggcatc tctgtatcca caccaactgg aagcacagcc
    42061 tataacaaat ccttaggtgg agctgtattg cacccaacga ttgaggccct tcagctaaca
    42121 gaaatctcga gcctgaacaa tcgtgtattt agaaccttgg ggtcctcagt gattattcct
    42181 aaaaaagata aaattgagct tgttccaaaa agactaggcg tttatactgt ctctgttgac
    42241 aataaaacct accacttaaa aaatgtggtt aaggtggaat attttatcgg caatgaaaag
    42301 attcattttg tgtcctcacc tagccacacc agcttttggg aaagggttaa ggacgctttt
    42361 attggggata gtgaatcatg aggtttgaat ttgttgcaac taaaaaaaca aaggtaaaga
    42421 cccttttaaa agagcacgat gtgtcaaagg gattgctcgc taagattaaa tacaagggtg
    42481 gcaatatatg ggtaaatggc gttgcgcaaa atgccattta tttattggat attggtgatg
    42541 tggtggctat tgatattcca aatgaggagt cctttgagca attgacagcg atttcgcatg
    42601 accttgatat tgtgtatgag gacgaacatt ttctcattct caacaagcct gctggctacg
    42661 ctagcattcc aagtgctatc cattctaata ctatagctaa ttttatcaag gcttattata
    42721 tcaagcagga ctatcccaat aaacaggttc atattgtgac gcgcttagat cgggatacca
    42781 gtggcttaat gctctttgcc aagcatggct atgcccatgc cagattagat aagcagctac
    42841 agcaaagagc tatcaataaa cgctattatg ctcttgtttg tggtcaggag aggcttccag
    42901 atcaaggtga gattatagct cctattggcc gtacggacga cagcattatc acaagaactg
    42961 tcacgccaaa gggaaagtat gctaagacaa gctacaaggt cattgcccgc tatcctgaaa
    43021 atgtctctct agtggatatt acgctgcaca ctggtcggac ccatcaaatt agggtacatt
    43081 ttgctcatct tggttttcca cttttgggag atgatctgta tggtggtcga ttggaccttg
    43141 gcatgactag acaggcgctg cattgtcacc atcttagctt tacgcaccca tttacagaaa
    43201 gtagaagcga tcatacaata tgcttgacag atgactttga gagcgttatc atagatttac
    43261 agaaaaaaga tagaggttag ttaatgagta ttcgtaattt atttggtggt ttaagggaaa
    43321 aaattgtcgg caaaaacatg aagattgttt tccctgaggg aaatgatgag cgtgttgtac
    43381 gtgcagcagc acgtctaaag tttgaaggtc ttgttgagcc aattattctt ggtcaggcag
    43441 atgatattcg cagcctgcta acacagctag gctttgctga gcagcactat acaatcatta
    43501 acccaaatga ttatgctgat tttgagaaaa tgaaagcagc ctttgtagag cttcgtaagg
    43561 tcaaggcaac gcttgaagat gctgatagac tgcttagaga tgtcaattac tttggtgtta
    43621 tgctggttaa gctaggctta gcagatggca tggtttcagg ggctattcat tcaacagctg
    43681 atacggtgcg tccggcgctt cagattatca agacaaagcc aggcatttct agaacatcag
    43741 gtgtcttttt gatgaatcgc gaaaatacag agcagcgttt agtgtttgct gattgtgcca
    43801 ttaatattga cccaactgct caggagctcg cagaaattgc ggtaaacaca gcagatactg
    43861 cgaaaatttt tgatattgat cctaaggttg ccatgcttag cttttcaaca atgggctctg
    43921 ctaaagcccc acaggttgaa aaggttcaag aggccgtccg tattgctaag gaattgaggc
    43981 cagagcttgc tttagacggt gagcttcaat ttgacgcagc ctttgtacca agtacagcag
    44041 cgatcaaagc ccctgattca tcagtggcag gccatgcgaa tgtttttgtc ttcccagatt
    44101 tacagtctgg aaatattggc tataagattg ctcagcgctt aggcatgttt gatgctatcg
    44161 gaccaatcct gcaaggattg aacaagcctg ttaatgattt atcacgtggc tctagtgcag
    44221 aggatattta caagctagct attattacag cagcgcaagc gcttgaaaat gagtctatca
    44281 attaactgct aatagccatt aagttcacaa ggcttagcta tagtagatgt tgcttaaaac
    44341 gagttggata agccagctcg ttttttcaga aagtgaggaa ggaaatgaca aagattgcat
    44401 tagtaacagg cgcctctgct ggctttggta aagccattgc agagcagtta atagcccaaa
    44461 acatcaaggt gatcggagca gcccgccgca tagaaaagct aagagagcta gaaggtattt
    44521 ttggttctga gaggttttat ccgcttcaaa tggacgtttc agaaccaact gccattgata
    44581 aagcacttgc agaattacct aaagaatggc aggccattga tattttagtt aataatgcag
    44641 gactagcctt aggacttgat aaggcctatg aggctgatgt cgccaactgg ctaaccatga
    44701 ttaatactaa tattattggg cttatctatt taacacgtca ggtattaccg caaatggtaa
    44761 gcagcaacaa tggcatgatc atcaatatcg gctcaactgc tggcactatt ccctatccgg
    44821 gagctaatgt ttatggggct tcaaaagcct ttgttaagca gttttcgctt aatttaaggg
    44881 cagatttagc aggaacaaat atcagggtga ccaatattga gcctggcctt tgtgagggaa
    44941 cagagttttc tcatgttcgc tttaagggtg accatgagcg tgttaaagca ctttatgcag
    45001 gtgcacatgc tattcagcca agggatatcg caaatactgt ctcatggatt attgatcagc
    45061 cagagcatgt taacattaac cgcgtggaaa tgatgcctgt ctcacaaagc tatggttctc
    45121 agcctgttag ccgtcatgac taagaattac aagagcagat gtaaaaggat tgtcgaagtg
    45181 caacccaaaa agacttaaag cctagctgtt ttatagcctg gctttaagtc tttttctcta
    45241 atttttctta gaaatgatcc gaaagagaag gtccagatgt gacatctgac cacccaacaa
    45301 tggcctgccc tgtttcttcc aaatagtgct gcagcatagg cttgaagtcc aaaatcatgt
    45361 catagacccc aacaaattgc ttggtatcat cgtacaaggc ttgatattgc tgcatataaa
    45421 tatgatcctg tgaagcagtc ggaataagat acagcttact gccagttgcc gccttgtgca
    45481 aatcagtcaa gatccaatcc tcaatgacat catgcttatc agaagcaaaa aaattgccat
    45541 taaagcgatg attatcaaag atgatctgcc cctgatgatc agcaattcta gcctgaaggg
    45601 gaagataggt taaaaaatgt ggggctaagg cttggtaaaa ttgcatgagg tatttagcaa
    45661 gtcttaaagt ttgctgacta tcagtaaagg tatgatcact aacggtaaat ccttgctctt
    45721 tgtctgcctg attaaaataa agtacaggta gtgaggcttc aaggttctga aaggtaaaaa
    45781 tggcctgagc ctttttgagc tgctcagtag tcagctgacg gacaatagtg atatgaaaca
    45841 gatagctaaa ctcttgtgat aaggtggtaa aaaaagtctt ttgcagatta ttcttatcat
    45901 caaccagtgc taaggtataa atcgttttag tcataaggct atcatagctt tattttgttt
    45961 aaatagcaat gaaacagcct tttagtctac agacttagtt gatagcttaa taaaagaaag
    46021 caatatgaaa aaatgattaa agcaaactag ttgacttgtt agtttaaact ttttataata
    46081 aatcaaatga gaagataata tgaggcttag cctaagctgc tgagcttatc tgataatcat
    46141 tcttcttagc actgagataa ccccctttat cgattaattg gagaatctat gatacgtttt
    46201 aataatgttt ccaaaacctt tggtcacacc aaggtgctgc aggagcaaag ttttcaaata
    46261 cagaatcgcg aattttttgt gctggtcggt ccaagcggct ctggcaaaac aaagctctta
    46321 aaaatgatca attgccttac tgaaccaagc tctggcgaaa ttctattaaa cggaaggcca
    46381 caaaaagagc tagatttgcg agatatgcgc ttatctattg gctatgttct tcagcaaatt
    46441 gccctgtttc caaaccttac agttgctgaa aatatcgcta ttattccaga gatgaagaag
    46501 tggtcagaca aagagattag aactaagaca gaggaattgt tagataaggt tggattgcct
    46561 gcaagggatt atctaaatcg ctatcccagt gatttatccg gtggagagca gcagaggatt
    46621 ggtattgttc gtgccatcat ttctcacccc aaggtgctgt taatggacga gccgttttca
    46681 gccttggatc ctatttcacg caagtaatta caggacttga tgttaagtct tcacaaggag
    46741 tttgatatga caattgtctt tgttactcat gatattgatg aggctatcaa gcttggagat
    46801 cgtgtggctg ttttaaatga agggcaaatt gttcaactgg atcgaccaga tgcgatcata
    46861 gctgcgcctg ctaatgattt tgtagcaagt ctatttggag gtcgtgatta tgcctagttt
    46921 actgatgacc ttttgggatc gttttggtga ttgggcaagg gcattaggag agcacttgca
    46981 gatttctctt ctttctttgc tggctgcctt gctgataggc attccgcttg cagctctgtt
    47041 gagtaaaagt aagcgctggt caaatatcat cttgcagctg acaggtgttt ttcaaaccat
    47101 tccttcccta gccttgttgg gactatttat ccctctaatg ggaatcggaa ctgctccagc
    47161 tgtaacagct ttggttattt atgccatatt tcctatttta caaaatacga ttactggctt
    47221 aaatgctatt gatccaagtc ttgtagaggc cggaacagcc tttggaatga ccaagtggga
    47281 gcgactgaaa atatttgaaa ttcctattgc tatgccagtt attatgtcag gtgttcggac
    47341 ctcagcagtg atgattattg gaacagccac cctagcttct ttgatcggag ctggcggctt
    47401 agggaccttt atcctattag gaattgaccg taataatgct cagctgattg tgattggtgc
    47461 tgtgtcgtca gccttgcttg cgatagtgtt taacagtctt ttgtgatacc ttgagaaggc
    47521 ctcactgagg cgtattgcga taagctttgc tgcgacctta ttactgctct taatttccta
    47581 tactccaatg tttgtcaagc ggtttgttaa tcagtcaaat actctggtga ttgctggcaa
    47641 gctaggagta gagccggata ttttgatcaa tatctataaa gagctgattg aagaccagtc
    47701 caagcttaag gttgaattga aacctaattt tggcaagaca agctttttat acgaggcgat
    47761 taaatcagga gatattgata tttatccaga atttacagga accatcacct ctagcctatt
    47821 aaagaaaaag cctaagcttt ctaatgaccc taatcaggtt tacttagctg ctaaggaggg
    47881 gattgctgag caggatcagt tgacgctttt aaagcccttt gcctatcaaa atacctatgc
    47941 agtggcgatg cctgaaaaaa tagctgacga atttaacatt caaagtattt cagatgtgaa
    48001 gaaatatgaa aaacagctaa aggctggttt tacactagaa tttaaggata gagaggacgg
    48061 ctataagggc atacaggata agtatgatct acatttatca gttgcaacga tggagccagc
    48121 tcttaggtac caagccattc agtcaggaaa cattcagctg acagacgctt attcaactga
    48181 tgctgagatc gtgaaatatc agcttcgagt cttaaaggac gataagcagc tctttccacc
    48241 ttatcaagga gcgccattga tgaaggcttc cttactaaga aagcaccctc atctcaaaac
    48301 gattctcaat cagttatcag gaaagattac tgaagaggag atgcaagcaa tgaactatga
    48361 ggtgtccgta aagggcagag cagctagcct tgtggcacat gactaccttg taaaggccgg
    48421 tcttattgca agaaccaaat aagcaggcat gctagtctta ttctggactg gcatgcttta
    48481 tttatgtgat ttttagtctg tctggctctg caaggtgtgt gccaaataac cgctcgtttg
    48541 atgtgtggtt attgatttag tagctaagga ttggaatctt aaaataaaat ccgaacgttt
    48601 gtctaaaaaa agctttaaaa attgacaaaa cataaacgaa aggataaaat aaattaagga
    48661 aaggtaacat tttacctagc gatgcctcgg acaagcttga ggtcatagga aggtcatttt
    48721 atatagaagc ttatgtcagc tgcagatcag ggaagtcctt gctggattag tagctgaatg
    48781 ttgaaaaagg agagaaatga tgtttaatga catgcctgta tttgattatg aggatattca
    48841 attaattcct aacaaatgta tcatcaatag tcgttcagaa gcagatacga gtgtaagact
    48901 tggtaattat acctttaagc tacctgttat tcccgccaac atgcaaacca ttattgacga
    48961 aacaattgca gagcagttgg caagagatgg ttatttctat attatgcacc gctttgatga
    49021 ggaggggcgc aagcccttta tccagcgtat gcatgagcaa cagctcatcg cctctatttc
    49081 ggttggtgta aaggattatg aatacgattt cgtctcttct ttgaaggagg acgcacctga
    49141 gtttatcacg attgatattg ctcatggcca tgctgatagt gtgatcaaaa tgattaagca
    49201 tattaaggct gagctgcctg agacctttgt tatagctgga aatgtcggaa caccagaggc
    49261 tgttcgagag ctcgaaaatg ctggtgctga cgcaacaaag gtcgggattg ggcctggtaa
    49321 ggtttgtatc acaaaggtta agacaggctt tggaacaggg gggtggcaat tagctgctgt
    49381 acgttggtgt gctaaggctg ctcgtaagcc gattattgct gatggcggta ttcgtactca
    49441 tggtgatatt gccaagtcga ttcgatttgg ggcaacaatg gtgatgatcg gttcactctt
    49501 tgcaggtcat attgaaagcc caggcaagat ggtagaaatc gacggacagt ccttcaagga
    49561 atattatggc tctgcctctg aatatcaaaa aggggagcat aaaaatgtcg aaggcaagaa
    49621 gattttgctt ccaaccaagg gtcatctagc tgatacttta accgaaatga agcaggattt
    49681 acagtcatca atctcatatg ctggaggcag agatttggag agcctgcgtc gtgtgaatta
    49741 tgttatcgtg aaaaattcta tttggaatgg tgactctatt taaagccttg gctaaagacc
    49801 tagtctaaat aaggataagc aagctgattg atgctgagaa taagcacagc gtgtctatag
    49861 gacgcctgaa tgtctagtag ccagtaaagc ttttaggctt gctgattgga taggtcattg
    49921 tgcctatgtg cagcagggct ctagggactt agataaaaag gagacatgat gaggttactg
    49981 gaggagcgta tcctagctga tggaactgtt ttaggtgaga cgattttgaa ggtggatcaa
    50041 tttttaacac atcaggttga ctatcgcttg atgaaggaaa tcggtagagt atttgctgat
    50101 caatatgctg atttgggcat taccaaggtg gtcaccattg aagcctctgg tatcgcacca
    50161 gcagtttata ccgcagaagc tcttgaggtt ccgatgattt ttgccaaaaa gcacaaaaat
    50221 atcacgatga cagagggaat tttaacagca gaggtttatt cctttaccaa acaagtgaca
    50281 agtactgttt ctattgcagg aggactgcta tcaaaagaag atagggtttt gattattgat
    50341 gactttttgg ctaatggtca agcggcaaaa ggcttgattg atatcattca tcaagcaggg
    50401 gccaaagctg ttggcatagg cattgtcatt gaaaaatctt ttcaggctgg acggcaattg
    50461 cttgaggatt tgggagtaga ggtcacttca ttggctcgta ttaagcattt tgacaatgga
    50521 atagtaagct ttttggaggc tgatgcctga tgactgcttc ttatctctca gcattaagct
    50581 ttttacttgt atagctatac cagctttatt tcagtagcta ttggctggtg ataagggata
    50641 ttggtatggc ggtgcattac ggcgagccgt gggcagttgc ccttgcggct ttacgattta
    50701 gtatagacta tcaagaattg actgcttcct ttttatcgag atgaatcatt agacagacaa
    50761 tcatgatttg gcgtgaaggc tgctttcagt aaacattaca tcatcaaaaa tcagctaggt
    50821 attcacttag ctgattttta gtgcttataa tgtagccgaa aggctccctt taacccgtct
    50881 gagatagtaa cctgaccatc tttggtaatg ataatgcctt ccacctcagg cagcttattt
    50941 agctgactta ggacaaagga atgctctaag ccaaaaagac gactactcca tagctcacca
    51001 tcaagtgaga attggctgac aatggttagg ctagccatat tggtcttgat aggatagccg
    51061 ttgtgaggat caagaaggtg atgataagtt ttgtctttga tttgtaattg tctctcgccg
    51121 attcctgagg ttactacaga tttattgtta accttaatca cgccgacatg ctgtcctctt
    51181 ttttgattgg tctgctggat cccaacgtaa aacaagccat tatgtcgttg cttgttggtg
    51241 ccatgcacaa ggacatttcc acctagattg ataagagcag cagtgatacc gtctttaata
    51301 agaaatgcca tgagcttatc agcaatatag ccctttgcta gggcacctaa gtcgatagac
    51361 atgccctttt ctttcaaaaa aatacttcca aggctttgat ctaa
//
LOCUS       DARYXW010000004        49618 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.004, whole genome shotgun sequence.
ACCESSION   DARYXW010000004 DARYXW010000000
VERSION     DARYXW010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 49618)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49618)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49618
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.004"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            255..328
                     /locus_tag="TV191_000167"
     tRNA            255..328
                     /locus_tag="TV191_000167"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:289..291,aa:Arg,seq:acg)
     gene            417..902
                     /locus_tag="TV191_000168"
     CDS             417..902
                     /locus_tag="TV191_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComX"
                     /protein_id="HEL1506720.1"
                     /translation="MTDDLVRLFDKIKPIIMKLRQHYYIQLWELDDWLQEGRLILYRL
                     LVTYPELIEDEEKLYRYFKTKFSSYLKDVLRQQESQKRRFHKMAYEEIGSVGHAIPAG
                     GLGVDDYVAYQLIVKEVEERLTEGELSQFRALIRGERFEGRRALLRKIGPYFQDFTGE
                     K"
     gene            1040..1567
                     /locus_tag="TV191_000169"
     CDS             1040..1567
                     /locus_tag="TV191_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEL1506721.1"
                     /translation="MSVDDYRPTYAVEAVYDLRANDLLRQGITAVLVDLDNTLIAWDN
                     PDGTPEVRAWLDEMTIADISVVVVSNNTYSRVERAVSRFGVDFIARAMKPFAYGINKA
                     IDRYGFDRDEVIMVGDQLMTDIRASHRAGIKSVLVKPLVTSDAWNTKVNRWRERRVLA
                     KLEEKYGRLVYQKGI"
     gene            1567..2685
                     /gene="yqeH"
                     /locus_tag="TV191_000170"
     CDS             1567..2685
                     /gene="yqeH"
                     /locus_tag="TV191_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEL1506722.1"
                     /translation="MEELFCIGCGIQIQTTRKQEAGFTPAAALVKGIEAREIYCQRCF
                     RLRHYNDITDVHITDEEFLRLLHEVGDSDALVVNVIDIFDFNGSVIPGLSRFVAGNDV
                     LLVGNKKDILPKSVKDSKVTQWLTERAHEEGLRPLDVLLTSAQNKYAIKELIERIDQL
                     RQGRDVYVVGVTNVGKSTLINAIIQEITGDKDVITTSRFPGTTLDKIEIPLDDGSFIF
                     DTPGIIHRHQMAHYLSAKNLKFISPKKEIKPKTYQLNPEQTLFLGGLARFDFISGERQ
                     GFTAYFDNQLLLHRTKLEGADAFYDKQAGQLLTPPDKKELDDFPRLVRHEFLLDQKVD
                     VVFSGLGWIRVNANKETATKVAAWAPDGVAVVVRKAII"
     gene            2712..3053
                     /gene="yhbY"
                     /locus_tag="TV191_000171"
     CDS             2712..3053
                     /gene="yhbY"
                     /locus_tag="TV191_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEL1506723.1"
                     /translation="MLTSKQRAFLKAEAHSLKPIVQIGKNGLNDQIKTSIRQALDARE
                     LIKVTLLQNTDETIHEVAEILEEEIGCDTVLKIGRILILFKVSAKKDNILFKVSAKKD
                     NRKLSVKVKSI"
     gene            3137..3769
                     /locus_tag="TV191_000172"
     CDS             3137..3769
                     /locus_tag="TV191_000172"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEL1506724.1"
                     /translation="MALELLTPFTRVELEMEKKDSNRKQVGILGGNFNPVHNAHLVVA
                     DQVRQQLGLDQVLLMPEFKPPHVDHKETIDEKHRLRMLELAIQETEGLAIEEIELTRQ
                     GVSYTYDTMKLLIEQNPDVDYYFIIGADMVDYLPKWHRIDELIHMVQFVGVQRPKYKA
                     GTSYPVIWVDVPLLDISSSMIRDFIQSDRQPNHLLPKAVLDYIHKEGLYQ"
     gene            3766..4359
                     /gene="yqeK"
                     /locus_tag="TV191_000173"
     CDS             3766..4359
                     /gene="yqeK"
                     /locus_tag="TV191_000173"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEL1506725.1"
                     /translation="MMYQDYVGYRRDELLGKIAEQMSDKRFKHVLGVERAAIHLAERY
                     HCDPIKAGLAALLHDYAKECPDELFISLIDKYQLDPELLKWNNNIWHGMVGIYKLQED
                     LGLKDKGILRAIEIHTVGAAEMTILDKILYVADYIEEGRVFPLVDEARRIAELDLDKA
                     VAYETAHTVAYLASKAQPIFPQTIDTYNAFVHYLHEE"
     gene            4361..4714
                     /gene="rsfS"
                     /locus_tag="TV191_000174"
     CDS             4361..4714
                     /gene="rsfS"
                     /locus_tag="TV191_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEL1506726.1"
                     /translation="MRKEELLEIVIKAADEKRAEDMLALDLAGLTSLTDYFVIVTATN
                     SRQLEAIADNIRERVKEASGDASHVEGNSQTGWVLLDLNDVVVHIFSEDERYHYNLEK
                     LWHEAPAVELSHYLG"
     gene            4844..5587
                     /locus_tag="TV191_000175"
     CDS             4844..5587
                     /locus_tag="TV191_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1506727.1"
                     /translation="MQKNYDTFASVYDAIMDDSLYDKWTAFSLRHLPKNKEHQKLLEL
                     ACGTGIQSVRFAQSGFEVTGLDLSQEMLEVAKKRAQSAKKIITFVQGNMLDLSQVGSF
                     DVVTCYSDSICYMQDEIEVGDVFKEVYQVLNDGGIFMFDVHSIYQMDHLFPGYSYHEN
                     AEEFAMVWDTYKAEAPHSVVHELTFFIQAEDGHFLRFDEVHEERTYDILTYDILLEQA
                     GFKSFKVYADFEDQEPTKTSKRWFFVAQK"
     gene            5697..6797
                     /locus_tag="TV191_000176"
     CDS             5697..6797
                     /locus_tag="TV191_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEL1506728.1"
                     /translation="MTVTGIIAEFNPFHYGHQYLLSQAKGLKIVAMSGNFVQRGEPAL
                     VDKWVRAQMALENGADLVVELPFLVSVQSADYFAQGAVDILMRLGIDTLAFGTEQLLD
                     YQKLSRLYSEQAEHMTAYLATLPDHLSYPQKTQSMWEAFAGLSATGDRPNHLLALSYV
                     KASAGKKLQLQPIKRLGAGFHSEAKDQCLSSATAIRKHIADRAFVEKSSPNAALILRA
                     PQVTWEHYFPFLKYHILTAPDLTQFFQVNDELASRISAAIRSVATVDELVEAVATKHY
                     TKARVRRVLTYILVKAVEAPLPEGIHVLGFSKKGQAHLKTIKASVPLISRIGAKPWDQ
                     LTQRADTVYQLGHTDMPEQTWGCVPIRPEAMN"
     gene            7153..7860
                     /locus_tag="TV191_000177"
     CDS             7153..7860
                     /locus_tag="TV191_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEL1506729.1"
                     /translation="MKTVKEVSQLTGLSVRTLHEIGLLPPTMVGENGYRFYDAAALRR
                     LQDILLFRELAFPLKTIKQLLDSPSYDQQAALAAQIKMLELRKAHLEKVIAHARTLQK
                     GEETMTFDIYSKSQLEAFQLEAKERWGETEAYMAYEAKVNQPSAEQLIKDMGEIFSIF
                     GRMLDQPVAELAVQQQVKALQDYISQHFYDCSTEILSALGCMYLEDDRFRAAIDHMGG
                     AGTAAFVSRAISYYCQH"
     gene            8001..8717
                     /locus_tag="TV191_000178"
     CDS             8001..8717
                     /locus_tag="TV191_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1506730.1"
                     /translation="MGRKWANIVAKKTAKDGATSKVYAKFGVEIYVAAKQGEPDPELN
                     TALKFVIDRAKQAQVPKHVIDKAIDKAKGNTDETFVEGRYEGFGPNGSMIIVDTLTSN
                     VNRTAANVRAAYGKNGGNMGAAGSVSYLFDKKGVIVFKGDDADSIFELLLEADVDVDD
                     VEAEDGSITVYTAPTDLHKAILALRESGISEFQVTELEMIPQSEVTLEGDDLAVFEKL
                     VDALEADDDVQKVYHNVADV"
     gene            8939..9784
                     /locus_tag="TV191_000179"
     CDS             8939..9784
                     /locus_tag="TV191_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1506731.1"
                     /translation="MTIKRYLGLAGLAVLSVGMLAACGTKEKSASSTKDTPKEVIFAT
                     VGTTAPFSFEKEGQLTGYDIEVAKAVFKDAEKYKLQFKKTEWSSIFTGLDSGKYQMGG
                     NNISYTKERSVKYLFSYPIGATPSVLVVPKDSDIKSYDDIKGHSTQVVQGTTTAAQLK
                     AFNEEHADNPVELKFTNETITQMLTNLNEGKADFKIFDAPTVNAIIDNQGLDHLKTIE
                     LATSEQPFIYFIFSQDQEELQAFVNKRLEELTADGTLSKIAKKYLGGDYVPAKQDLKL
                     PTAKS"
     gene            10156..11001
                     /locus_tag="TV191_000180"
     CDS             10156..11001
                     /locus_tag="TV191_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEL1506732.1"
                     /translation="MNIKKAVGFVSLALASIALVACSGKQDDKNTLTIGVMTKTASDQ
                     ARWDKIEELLKKDKITLKYKEFTDYSQPNKAVANGEVDINSFQHYNFLDNWNKENKAD
                     LKAIAETYISPIHLFSGTSQDGKAKYQSVDELPDGAQIAVPNDATNESRALYVLQAAG
                     LIKLNVSGDKLATIANITENKKKLDIKELDASQTARALTSADAAIVNNSYAVPAKIDF
                     KTSLFKEKADENAKQWINIIAAQKDWEKSAKADAIKALIKAYHTDAVKKVVDKTSNGV
                     DVPVW"
     gene            11079..12449
                     /locus_tag="TV191_000181"
     CDS             11079..12449
                     /locus_tag="TV191_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEL1506733.1"
                     /translation="MTKTDQQYLTRLWEDQLTQDYLVSLGQLIASRSIFAQGIGLEET
                     AAYLKELFAQAGAEAIVDKTYAAPFVLARFNSSRPAAKTLIFYNHYDTVPADSDQKWT
                     SDPFTLTERDGYLFARGVDDDKGHIIARLTAVVRYLKEHADLPLNIVFMMEGAEESAS
                     VDLDRYLAKYADQLKGAELLIWEQGIRNEHDQLEITGGNKGILTFEMSVDSARCDIHF
                     KYGGVIESAAWYLLQALSSLRNHRGELLVPGIYQKVVPPTERELDLVETYAIENAQAL
                     KKLYGLELPMLQSERRQLLAAYYFQPSINIQGLWTGYQGQGVKTIIPSQATPKMEVRL
                     VPGLEPEYVFDQIRSYLLNKGFDQIKLTYTLGEMSYRSDLSSSAISQLIAAAQPFYPK
                     GLSLLPTSAGTGPMHTVFEALQVPIAAFGLGHSNSCDHAGDENIAIVDYCRHIALIEE
                     LITSYE"
     gene            12442..13506
                     /locus_tag="TV191_000182"
     CDS             12442..13506
                     /locus_tag="TV191_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEL1506734.1"
                     /translation="MSEPMIQLDHIDITFHQKKRVIEAVKDVTLHINQGDIYGIVGYS
                     GAGKSTLVRVINLLQQPTKGSITIDGELTFDQGKVQLSANSLREKRRDIGMIFQHFNL
                     MAQKTAKENVAFALRHSRLPKAERERKVTELLELVGLSERADNYPAQLSGGQKQRVAI
                     ARALANDPKILISDEATSALDPKTTKQILALLQELNRRLGLTIVMITHEMQIVKDICH
                     RVAVMQQGTLIEEGSVLDIFSNPREPLTQEFIKTATGIDEALEKINQQDIVKELPANA
                     ILAQLKYAGTSTDEPLLNQIYRQFEVTANILYGNIEILDQVPVGEMIVVFEGAAASIE
                     AAEKALHEAGVDVTILKRGA"
     gene            13507..14199
                     /locus_tag="TV191_000183"
     CDS             13507..14199
                     /locus_tag="TV191_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1506735.1"
                     /translation="MLELFQAYLPNVYELGWSGDAGWGVAIWNTLYMTIVPFIVGGAI
                     GLFIGLLLVLMGPDGVIENRLVCWLLDKLTSIFRAIPFVILIAILASFTYLIMGTTLG
                     ATAALVPLTFATFPFFARQVQVVFSELDRGVIEAAQASGATFWDIVRVYLSEGLPDLI
                     RVSTVTLISLVGETAMAGAIGAGGLGNVAISYGYNRFNNDVTWVATLIILLLIFAIQF
                     IGDSLTRHFSHK"
     gene            complement(14244..15629)
                     /gene="brnQ"
                     /locus_tag="TV191_000184"
     CDS             complement(14244..15629)
                     /gene="brnQ"
                     /locus_tag="TV191_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEL1506736.1"
                     /translation="MKEKNVYIVIGFMLFALFFGAANLIYPAFLGIYSGQNIPWSIIG
                     FCLTGVSLPLLGVIAVARSGSDDVESLARPISKWYAILYSSILYLSIGPFFAIPRTGA
                     TSFSVGIAPILGDSIINKAIYAVLFFGLSYFLAIRPSKLAESIGKFLTPTLLVVITIL
                     IIASFVHPAGDYGEAFNAGAGINNAFKDVPFIAGLIQGYGTMDALASLVFAILVIEAT
                     KQFGAKTDQEITKITLISGAIAILLLAFVYIFVGRIGATSQSLFPFVDGHFTLNNSAV
                     NGGQILSHASRFYLGSIGQAFLAIVIFLACLTTSTGLITSSAEYFHKLMPRVSHVAWA
                     TLFTLVSAFFYFGGLSVIINWSSPILYLLYPLTVDLIVLVLIQKSFGNAPLVYRTTIG
                     LTIIPALYDALATLSQLTKLFTLPDGLSYFFERLVPLGQFSMGWISFSILGFVLGLII
                     SKTKGLHPTAS"
     gene            16057..17271
                     /gene="sstT"
                     /locus_tag="TV191_000185"
     CDS             16057..17271
                     /gene="sstT"
                     /locus_tag="TV191_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HEL1506737.1"
                     /translation="MKRIRDLWVRTNLIKKIGIGVVIGLLLGILLPDVTAIGILGQLF
                     VGALKAIAPLLVFALVAQAISHQRSGQQTNMTLIIVLYLLGTFLAALVAVIANYLFPL
                     TLTLNTPVNTELSPPQGIVQVFQTLLLKLVDNPINALATANYIGVLAWALIFGLALKS
                     VPSDFKHLIKTAADVTSQIVVWIINVAPIGIMGLVFSTVSENGISILSDYALLILVLV
                     GTMLFVALVVNPLLAFVLTHQNPYPLVFRCLKDSGLTAFFTRSSAANIPVNLQLCEDL
                     GLSQATYLVSIPLGAMINMGGAAITINVLTLAAVNTFGIQIDFLTALLLSVVAAISAC
                     GASGVTGGSLLLIPVACSLFGISSDLAMQVVGVGFIVGVIQDSCETALNSSTDVLFTA
                     IAENAFWKQKKA"
     gene            complement(17625..18299)
                     /locus_tag="TV191_000186"
     CDS             complement(17625..18299)
                     /locus_tag="TV191_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEL1506738.1"
                     /translation="MLKRKTVGVLGLGIFGRTVARELSNYDQDVIAIDIRESHVKEIA
                     DLATKAAVGDITDKDFLIAVGVEQCDTVVIASGNNLESSVLAVMHCKKLGVPTIIAKA
                     KNKIFEEVLYGIGATKVITPERDSGKRVASNLLRHHIESIIYLEHGISMIEFTIPKSW
                     EGKSLSELDVRRKYELNIIGMRQKEVKTLDTNVQPFEPLEADTIIVAIANDHTFEKFD
                     YLGYLK"
     gene            complement(18309..19685)
                     /locus_tag="TV191_000187"
     CDS             complement(18309..19685)
                     /locus_tag="TV191_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEL1506739.1"
                     /translation="MKRSFFKSLSVTQRLTFSFAIVILIGSLLLSMPFTHYSNGPNTV
                     YLDHFFNVVSMVCVTGLSVVPVADVYNGIGQTIAMMLMQIGGLGLVTLIAVSTFALKR
                     KMRLSDQTLLQSALNRGDSKDLKKYLFFAYKVTFSLEAFAALVIMTDFIPRFGWKNGI
                     FNSIFLAVSAFCNAGFDNLGSSSLKDFVLNPTINAIITFLIISGGLGFAVWVDLGTAF
                     KKYFFERPHCYGITFKKFSNQSRLVLQTTLVILVLGTFLSWFLEKDNLNTIARYNLPQ
                     QLMVSFFQTVTMRTAGFATISYNDTLAPTNILYMIQMVIGGAPGGTAGGIKITTAAIT
                     FLLFKAELSGQSEVTFRNRIIANKTIKQTMTVLIFFFAVLMIGYILLLSVEPDIAPIP
                     LLFESISAIATVGVSMDVTPHLSSAGRLIIIVLMFVGRVGPITVLISLIQRKEKTIQY
                     ATTDILVG"
     gene            complement(20198..20920)
                     /gene="rsmG"
                     /locus_tag="TV191_000188"
     CDS             complement(20198..20920)
                     /gene="rsmG"
                     /locus_tag="TV191_000188"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEL1506740.1"
                     /translation="MTPQAFYLVLEQAGFALTNHQKEQFDTYFKLLVDWNRKINLTAI
                     TEENEVYLKHFYDSVAPLLQGYIPNEPLRLLDIGAGAGFPSIPMKIMFPKLDVTIIDS
                     LNKRIHFLQLLAKELGLEGVHFYHGRAEDFGQDKQFRGQFDLVTARAVARMQILSELT
                     IPFLKIKGKLIALKAQAADQELEEAKKALQLLFAKVLDHQPYQLPNGDGRYITLVEKK
                     KETPNKYPRKAGIPNKNHCKRL"
     gene            21056..21613
                     /locus_tag="TV191_000189"
     CDS             21056..21613
                     /locus_tag="TV191_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEL1506741.1"
                     /translation="MPMFLVIVALIGVLVVWLMVSYNGLVKARMHTKEAWSQIDVQLK
                     RRNDLIPNLVETVKGYANHEEKTLEKITSLRSRVADATTPQATMAASNELSKQVTSLF
                     AVAESYPDLKANSNFLKLQEELTNTENKISYSRQLFNTTTSHYNLKLESFPSNLVAKL
                     FGFKPSEFLQVPEAEKEVPKVDFTV"
     gene            21650..22543
                     /gene="htpX"
                     /locus_tag="TV191_000190"
     CDS             21650..22543
                     /gene="htpX"
                     /locus_tag="TV191_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEL1506742.1"
                     /translation="MLYQQISQNKRRTVILLFAFFVLLVVIGAAAGYLLADSYQLGAA
                     FALIIGAIYAFSMIFQSTSLVMGMNKAKEITVNDAPDFFHIVEDMALVAQIPMPRVFI
                     IDDPSLNAFATGSSPQNAAVAATTGLLKVMNREELEAVIGHEVSHIRNYDIRISTIAV
                     ALASAVTLISSIGGRMMWYSGGRRRDNDRNDNGFGAIMLIFSILSLILAPLAASLVQL
                     AISRQREYLADASSVALTRNPEGMIRALQKLSNSQPMTHPVDDASAALYINEPRKKEK
                     LSALFSTHPPIEDRIERLKHM"
     gene            22831..23364
                     /locus_tag="TV191_000191"
     CDS             22831..23364
                     /locus_tag="TV191_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEL1506743.1"
                     /translation="MLSVSDIRKRPEGIRFEREYDVKEALLIRDPQVIDINNVRASGR
                     AQFDDGLYLLEYQLGYQITLPSSRSMAPVVLDEMQTVQELFIEEADVASKQEMVDENL
                     VLVLSEDQLDLEESIIDNILLAIPLQVLTEAEKESQILPTGEDWAVLTEEQYQAQQKE
                     KAKDNSPFAGLQGLFDE"
     gene            23549..24235
                     /gene="covR"
                     /locus_tag="TV191_000192"
                     /gene_synonym="csrR"
     CDS             23549..24235
                     /gene="covR"
                     /locus_tag="TV191_000192"
                     /gene_synonym="csrR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CovR"
                     /protein_id="HEL1506744.1"
                     /translation="MTKKILIIEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALE
                     KDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMTARDSIMDVVAGLDRGADDYIVK
                     PFAIEELLARIRAIFRRQDIESEKKTPSQGVYRDLVLNPQNRSVNRGDDEISLTKREY
                     DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTV
                     RGMGYVIREK"
     gene            24239..25729
                     /locus_tag="TV191_000193"
     CDS             24239..25729
                     /locus_tag="TV191_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing protein"
                     /protein_id="HEL1506745.1"
                     /translation="MAKQKKYKKTLPKRLSNLLFVLFFCIFSAFTLLAYISTNYFLLK
                     REKQTIFQAVNIVRVRLSEVDSNFTLENLAEVLYKNDRTHLKIDDANGSRIIRSERNI
                     TNTLNANEDIYVYNVDKQMIFTTDDEEASPGLNGTIGKVTKDHIEEQYKGFSMTQKVY
                     SNKTGKFVGYVQVFHDLENYYMIRARLFFWLLVVELFGVGLAYFIILIVTRNFLKPLN
                     NLHDVMRTISKNPDNLMLRSGISSGDEIEELSVIFDKMLDKIETHTRLQSRFISDVSH
                     ELRTPVAIIKGHIGLLQRWGKDDSAILDESLTAAAQEVDRMAIMINDMLDMIRVQGSF
                     EGHQNDTTVLESSIETVVGNFRVLREDFDFTWYSENQRTLAKIYKNHFEQALMILIDN
                     AVKYSRKEKKIVIELAVNASNEAVVKVKDRGEGISEEDIKHIFERFYRTDRSRNRTST
                     QAGLGIGLSILKQIVDGYHLHMEVESELNKGSVFILRIPLADHQGS"
     gene            25920..26414
                     /gene="nrdR"
                     /locus_tag="TV191_000194"
     CDS             25920..26414
                     /gene="nrdR"
                     /locus_tag="TV191_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEL1506746.1"
                     /translation="MRCPKCNYNKSSVVDSRQAEDGNTIRRRRECESCHTRFTTFERL
                     EELPLLVIKKDGTREQFSRDKILNGVVQSAQKRPVSSTDIENLISRIEQKVRTAYENE
                     VSSTVIGNLVMEELAELDEITYVRFASVYKSFKDLDEIEELLQQITNRVRGKKKSSVD
                     DEAY"
     gene            26398..27561
                     /locus_tag="TV191_000195"
     CDS             26398..27561
                     /locus_tag="TV191_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase loader"
                     /protein_id="HEL1506747.1"
                     /translation="MMKPIDTFSYIKHNQVQYDSSSLIQLYFPIIGNDAVAVYQYLVH
                     FFDDGSGAHKFSDILNHLQFGMKRLEEALVMLTAIDLLVLYQLPDAYLIKLHQPLGRE
                     AFLNNPIYRRLLEQKIGDVAVLELQMVIPNQARNISKTFSDVFGIDSQELKQPQPSKI
                     NFDLDSFQQLMRRDGLRFEDHQKDVISLYSISEQYHLTWFDTYQLAKATAVGGSIRPE
                     RMLVKKQQEGAQKTSESFSPAEQVVLRESKQDTPLVFLEKIKKARRARVTKDEKELLL
                     TLARMNFLDEVINIMVLYTFNKTKSANLHKTYLMKMANDFAYQRVLTAETAIIKTRAF
                     GERKQQAKSQQSNVPKWSNPDYQEKTSQEEQAKLEQFKQAALKRLENLGKSGD"
     gene            27562..28470
                     /gene="dnaI"
                     /locus_tag="TV191_000196"
     CDS             27562..28470
                     /gene="dnaI"
                     /locus_tag="TV191_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEL1506748.1"
                     /translation="MEKIGKMVEHLGQASRVASAELIEAILADQEVAEFIKAHQLSQA
                     EIKLSLSKFNQFLVERRKYQTGDETYIAKGYQPILVMNEGYADVSYLETRELVEAQRQ
                     AAIADRIHLVSLPRSYRRVSLSAVDVNNASRMQVFSELLDFVEQYPAAEQKGLYLYGD
                     MGVGKSYLMAAMAHELSEKKGVSTTLLHFPSFTIDVKNAISNGSVKEEIDAIKHVPVL
                     ILDDIGAEQATSWVRDEVLQVILQHRMLEDLPTFFTSNYSFADLERKWAKIKGNDETW
                     QAKRVMERVRYLARECHLEGVNRRQG"
     gene            28520..29830
                     /gene="der"
                     /locus_tag="TV191_000197"
     CDS             28520..29830
                     /gene="der"
                     /locus_tag="TV191_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEL1506749.1"
                     /translation="MVLPTVAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYT
                     TGEWLNRQFSLIDTGGIDDVDAPFMEQIKHQAHIAMDEADVIVFVVSGKEGVTDADEY
                     VSKLLYRTNKPVILVVNKVDNPEMRNDIYDFYSLGLGDSFPVSSVHGIGTGDVLDAII
                     DNLPIEEPVENDDVIRFSLIGRPNVGKSSLINAILGEERVIASPVAGTTRDAIDTSFT
                     DESGQAYTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDIVLMVINAEEGIRDYDK
                     RIAGFAHEAGKGMIIVVNKWDTIEKDNHTVARWEADIRDQFQFLTYAPIIFVSAVTKQ
                     RLNRLPELIKRISDSQSQRISSAILNDVIMDAIAINPTPTDKGRRLKIFYATQVSVKP
                     PTFVVFVNEEELMHFSYLRFLENQIRAAFTFEGTPIKLIARNRK"
     gene            30171..33263
                     /locus_tag="TV191_000198"
     CDS             30171..33263
                     /locus_tag="TV191_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL1506750.1"
                     /translation="MARLIPGRIRNQGIELYEQGLVKIIDDRTDLLRAEVDTYQVQYG
                     INDEDIRCQCDYFERKQYCQHIAALEYFLKNNQKGKSLSEQLNNQLESKEETKKLTSF
                     GSLFLDSLHMNEDDTTKYRLLASGAKSPFSSDYWWSLKINRLPGEKAYVIRDIKAFIH
                     LVKVEGFYQIGKNYFESLSILQFDQASQELIRFLWRLSTHSDKLDYEWLFPNHARHLR
                     LPAGFFEEGIDLLTGLYEFSFETSSQTYSHLYVRPLEAEAGLFQFTVDVHRSSIELYI
                     KEKNIEYFFNNEYLLYMNTFYHLSLKQQKMVQAIRSLPIEADLAKHIHFDLDDQAKLA
                     ASLLEFRELGQVKAPKSFDIRDFQVTFVFDITEKGELTSQLIFDYGSIQISDKASLDQ
                     LPFASHYKKESSIYRALKRFGLSPQFFAKKALTDPKDWYRFFTEAVPYFESLGRVQLS
                     SKLQDQRLMESPQLTVKREGGLLDISFDFSTVCQTDIEKALATLFSDRSYFVNQSGKL
                     VVFDEETQKISRSLQELRAKQLANGHLQLEGIAATQLSHLFSDLSSVHFSEELETLIK
                     DLQHPDRFELGELAVKAKVRDYQLQGIKWLSVLDKYGFGGILADDMGLGKTLQIIAFL
                     SSRLTETSKVLILAPSSLIYNWLDEFSKFAPQIDAAVSYGLKPARDALIQEGHQVTIT
                     SYSSFRQDLETYQANDYDYLILDEAQMIKNAQTKIAQSLRAFDVKNCFALSGTPIENK
                     LLEIWSIFQIVLPGLLPSKKAFLKMEARDVSRYIKPFVMRRKKEEVLPELPELIEMNY
                     YNEMSDGQKAIYLAQLRQMQERLSAATDDDINRSKLEILSGITRLRQICDTPSLFMDY
                     QGGSGKLDNLRTLLLQIKENGHRALLFSQFKGMLALVKQEMDQLGLSSYTITGSTPAN
                     DRQEMTRAFNNGSKDAFLISLKAGGVGLNLTGADTVILIDLWWNPAVEMQAISRAHRI
                     GQEDNVEVYRLITRGTIEEKILELQENKRHLITTVLDGKQGLASMSVEEIKEILGLQP
                     "
     gene            33467..34060
                     /locus_tag="TV191_000199"
     CDS             33467..34060
                     /locus_tag="TV191_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1506751.1"
                     /translation="MTKHAFPLVADGEPIIESARQMALYENEDLITNIAGSYQDKHYD
                     DIIRDHQFAEKTPVVSKGSLHHSPVVDEDHSYAQKARRQAKQDVKEKRQAYIAKNMAY
                     SPKQASKKGQSGAFSSKKPATELSRFTEKLNQESYILAELPRQYKEPQNTSQAAVKKN
                     NYDFLKRSQIYNHQEDRDHREKTIAQELNLSRFEDIK"
     gene            34104..35435
                     /locus_tag="TV191_000200"
     CDS             34104..35435
                     /locus_tag="TV191_000200"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEL1506752.1"
                     /translation="MSKTYHFIGIKGSGMSALALLLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFSEDNISPDMELIAGNAFREDNNSEVAYAMRHQLPFKRYHEFLGEFMKQ
                     FTSLGVAGAHGKTSTTGLLSHVLKHMTATSYLIGDGTGHGAADARYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTGLDDVFNAFNDYAKQVKKALFVYGEDEELRKISSPA
                     PIYYYGFEDTDDFVAFDITRTTNGSDFKVKHKGHAIGQFHVPAYGRHNILNATAVIAN
                     LFIAGFDMKLVAEHLKSFSGVKRRFTEKVINDTIIIDDFAHHPTEIIATLDAARQKYP
                     NKEIIAIFQPHTFTRTIALLDDFAHALNEADSVYLAPIYGSAREVDKGDVKVEDLAAR
                     VERPAKVISVDNVSPLLDHDNAVYVFMGAGDIQLYERSFEELLANLTKNNQ"
     gene            35483..35965
                     /locus_tag="TV191_000201"
     CDS             35483..35965
                     /locus_tag="TV191_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1506753.1"
                     /translation="MLIRHVNQTDWEIIADIEQANFSPQEAVAANVIKERAELISDTF
                     LVAVIANQFVGYIEGPVIAEPRLEDHLFHGVTKNPARGGYIAITSLSVAPGYQKQGIG
                     TALLAAMKDLAVAQDRLGIILTCHDYLIPYYEMNGFQDQGLSASKHGGSVWYQMLWQP
                     "
     gene            36074..37648
                     /gene="mltG"
                     /locus_tag="TV191_000202"
     CDS             36074..37648
                     /gene="mltG"
                     /locus_tag="TV191_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEL1506754.1"
                     /translation="MALTDFKDDEQRRQQQKSFKEKILAELEKANQIRKEKEEELFKK
                     DLEVQEAARRTAQLYAEYKRQEALSNNPKQASDIAAASQETTSTASTAHTSAIKLEET
                     AVATGDQALSPPEEPALSESLLKEEASVEGQTKKGGPVRRKTSKRQQTDRMAKKISTV
                     LISSIVAIIVVIGLAGTAYVYSALNPVDKNSDDFVQVEIPAGSGNKLIGQILEKEGLI
                     KNSTVFSFYTKFKNFTNFQSGYYNLQKSMSLEDIAQALQEGGTAEPTKPVLGKILIPE
                     GYTIKQIAKAIETNSRAKNRSKAKTPFHSKDFLNLVTSDAFIQEMAKKYPKLLGDLPS
                     KEVATYQLEGYLFPATYNYYKETTLKDLAEEMIAAANANLAPYYEAIAASGKTVNEVL
                     TLASLVEKEGSTDDDRRQIASVFYNRLNNGMALQSNIAILYAMGKLGEKTTLAEDAAI
                     DTTINSPYNVYINTGLMPGPVDSPGLAAIEATINPAATDYVYFVADVRTGEVYYAKTF
                     EEHSANVEKYVNSQIQ"
     gene            37721..38203
                     /gene="greA"
                     /locus_tag="TV191_000203"
     CDS             37721..38203
                     /gene="greA"
                     /locus_tag="TV191_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEL1506755.1"
                     /translation="MAEKTYPMTAAEKEQLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYDAAKDEQAFVEGQISTLETKIRYAEIIDSDAVAKDEVAIGKTVVVQEVGTQT
                     TDTYHIVGAAGADIFSGKISNESPIAQALIGKKTGDKVKIESPAATYEVTIISVDKTQ
                     "
     gene            complement(38444..39364)
                     /gene="yidC"
                     /locus_tag="TV191_000204"
     CDS             complement(38444..39364)
                     /gene="yidC"
                     /locus_tag="TV191_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003105894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEL1506756.1"
                     /translation="MKLKTNRILFSGLALSVLLTLTGCVGRDAKGHPEGIIWDYLGKP
                     VSFLIDYFANSTALGYGLAIIVVTIIVRTIILPLGLYQSWKASYQSEKMAYLKPFFEP
                     INQRIKNATSTEEKMAAQTELMAAQRENGVNPLGGIGCLPLLIQMPFFSAMYVAVQFT
                     KGVSTSTFMGIDLGHRSVLLTAVIAALYFVQSWLSMMAVPEEQREQMKAMLYTMPIMM
                     IVMSFYLPAGLGLYWLVGGFFSIIQQLITTYLLKPRLRKQIAEEFAKNPPKAYKSHQP
                     RKDVTAEKQALSTSKRTKLNRNAGKQKKRR"
     gene            complement(39447..39725)
                     /locus_tag="TV191_000205"
     CDS             complement(39447..39725)
                     /locus_tag="TV191_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000755490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEL1506757.1"
                     /translation="MKKVRLIVSGRVQGVGFRYSTYALALEIGDIYGRVWNNSDGTVE
                     ILAQASDPAKMTRFIQEIRKGPSKWAKVTYVDVNPSHFEDFHDFRISN"
     gene            40018..40755
                     /locus_tag="TV191_000206"
     CDS             40018..40755
                     /locus_tag="TV191_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEL1506758.1"
                     /translation="MIITSKANHLIKQAKKLLQKKHRKHSYLIEGWHLFEEAQRSGQE
                     LIHIFVLEEMAERLSGFDQVVIVSPEILKELTSSPNPQGIIAEVKLCQQALPTSYAGK
                     YLILEDIQDPGNLGTIIRTADAAKFDGVFLSEKSADVYNQKTLRSMQGSHFHLPIWRT
                     DIYQVSQVMQQQKIPVLATTLSQDSIDYKDLSARSSLALVLGNEGQGISPEMAALADQ
                     LIHISMPGQAESLNVAVAAGILIFSLI"
     gene            40794..41294
                     /locus_tag="TV191_000207"
     CDS             40794..41294
                     /locus_tag="TV191_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEL1506759.1"
                     /translation="MHYTEDTEYMEHVGHLIAHPRFQRLGDIVQHHHSTRLEHSVNVS
                     YSSYRLAKRLGLDAKSTARGGLLHDFFYYDWRVTKFNKGHAWVHPRIAVRNAKKLTAL
                     NKKEEDIILKHMWGATIAFPRYKESYIVTFVDKYWAVKEAMTPLRQKWTNRRFLRRKT
                     LQSHNH"
     gene            41313..42002
                     /locus_tag="TV191_000208"
     CDS             41313..42002
                     /locus_tag="TV191_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEL1506760.1"
                     /translation="MNDNVIYTQSDAGLSHFFAKVYSLVGMGVGLSAFVSYLMLFPFR
                     QNLVSIVLDHPMVYYGAAIVELVLVFVASGAARRNTPAALPLFLVYSALNGFTLSFII
                     AAYAQTTVLQAFISSAAVFFAMSLLGVKVKRDLSGIRKAMFAALIGIIVASLVNLFIG
                     SDLMSYVISLISVLIFSGLIASDNQMIKQVYQASNGQVGDGWAVAMALSLYLDFINLF
                     ISLLRLLGRND"
     gene            42396..42638
                     /locus_tag="TV191_000209"
     CDS             42396..42638
                     /locus_tag="TV191_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEL1506761.1"
                     /translation="MSTAIWILLIIVALTAGLFGGIFIARKQIEKEIGEHPRLTPEAI
                     REMMSQMGQKPSEAKIQQTYRNIVKQSKAAMTKGKK"
     gene            42818..43612
                     /gene="racE"
                     /locus_tag="TV191_000210"
     CDS             42818..43612
                     /gene="racE"
                     /locus_tag="TV191_000210"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEL1506762.1"
                     /translation="MDNRPIGFLDSGVGGLTVVSELMRQLPHEKIIYIGDSARAPYGP
                     RPAEQIREYTWELVRFLLTKHVKMIVFACNTATAVAWEEVKEALDIPVLGVILPGASA
                     AIKATSGGKVGVIGTSMTISSGIYQEKIQLLAPTVQVTSLACPRFVPIVESNEISSSV
                     AKKIVYETLAPLVGKIDTLVLGCTHYPLLRTIIQNVLGPQVKLIDSGAECVRDISVLL
                     NYFEINGSRDDEHRRHHFYTTAGSDSFQAIASAWLNQTIDVEHVTL"
     gene            43609..44598
                     /locus_tag="TV191_000211"
     CDS             43609..44598
                     /locus_tag="TV191_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEL1506763.1"
                     /translation="MSDNIYEYKDKDNWFIGKMTGHNLMAGWGVNHELIAKIDDMLGA
                     IAGDVDWESPVGYDVTVIRYASPFALISFVVGMINQKANRALKVVRHSGAILVTENER
                     LLAVHMPDDGVPVADFFGQQADGFGDTILIATRNEGKTKEFRRLFGDMGYRVENLNDY
                     PELPDVAETGVTFEENARLKAETISRLTGKMVLADDSGLKVDILGGLPGVWSARFSGP
                     DATDETNNAKLLHELAMVFDQKDRSAQFHTTLVVAAPGKDSLVVEADWHGYIATKPKG
                     EHGFGYDPLFIVGETGRHAAELAADEKNKLSHRGQAVKRLMEVFPAWQAKQSL"
     gene            44574..45095
                     /locus_tag="TV191_000212"
     CDS             44574..45095
                     /locus_tag="TV191_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEL1506764.1"
                     /translation="MASKTIIVMSDSHGDREVVAAIKGRYLGKVDAIFHNGDSELESS
                     DPIWEGIHVVAGNCDHDSGYKDSLVTSFDGLTIAQTHGHLYHINFTWDRLDYFAQETG
                     ADICLYGHLHRPAAWQLGKTVFINPGSVAQPRGEVNEKLYARVEWTAACIRVDYFTCQ
                     HKSYPSLSKEFKR"
     gene            45092..45553
                     /locus_tag="TV191_000213"
     CDS             45092..45553
                     /locus_tag="TV191_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEL1506765.1"
                     /translation="MIAKEFEAFLISHLDSYLIPAEELAIFINTHNADHVMLLLVSNG
                     FSRVPVITKEKQYVGTISISDIMTYQAKRQLTDWEMTQTNIGDMVNTKIETINITSSL
                     TEIMHKLVDFPFLPVVNDDNRFIGIITRKSILKAVNSLLHDFTDEYTITKK"
     gene            45550..46296
                     /gene="xerD"
                     /locus_tag="TV191_000214"
     CDS             45550..46296
                     /gene="xerD"
                     /locus_tag="TV191_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEL1506766.1"
                     /translation="MIAFIEPFLASKSLANNSQQSYRYDLRQFCQQVGQRINPETLAL
                     YQQSLSGLTVAAKKRKLSTVNQFLYYLYQQKALTDYFKMDDRIEASFSLKPQLTRLDT
                     SAFYAETAFLKGQLIALLILELGLTPSEIAGLRLADFDLGLQVLRLQSHRGIRVMTLS
                     KALLPFLEKATEAQQLYLFDHDAKPFSRQWFFNQLRDFLESIGCAELSAQSLREQFIL
                     NEKAAGKSIIEVAQLLGLKSPITLEKYYKM"
     gene            46296..47003
                     /locus_tag="TV191_000215"
     CDS             46296..47003
                     /locus_tag="TV191_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEL1506767.1"
                     /translation="MDIKVKDFEGPLDLLLHLVSKYEVDVYQVPIVEVIEQYLAYIET
                     LQAMRLELAGEYMLMASQLMLIKSRRLLPKLVDKEPDEEDLEQELLGKIEEYSRFKAL
                     SQELASQHDKRALLFSKPKQELIFEQAVLQKDKTVMDLFLAFSQLMAAKQEAFKYNHT
                     VIERDDYRIEDMMELIEARLELEQELTLTDLLKHCDHLNEAITLFLASLELIKRQLVG
                     IEQTSHFGQIVLRKEIQ"
     gene            47000..47539
                     /locus_tag="TV191_000216"
     CDS             47000..47539
                     /locus_tag="TV191_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEL1506768.1"
                     /translation="MTYLSQLEALLFVAGEEGLSLRQLASLLELTPTALQQQLDKLSQ
                     KYKEDKESGLCLIESSRTYKLVTKECLAPLLKDYAKAPINQTLSRASLEVLSIVAYKQ
                     PITRIEIDEIRGVNSSGALSKLVAFGLVQEAGKKEVIGRPNLYATTDYFLDYMGINHL
                     EELVDISSIAVEEQETTLF"
     gene            47776..48498
                     /locus_tag="TV191_000217"
     CDS             47776..48498
                     /locus_tag="TV191_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEL1506769.1"
                     /translation="MRINKYIAHAGLASRRKAEELIKRGLVTLNGQVITDLATTVKSG
                     DLVEVEGIPIYNEEKVYYLLNKPRGVISSVSDDKGRQTVIDLLPQVKERIYPVGRLDW
                     DTSGLLILTNDGDFTDKMIHPRNEIDKVYLARVKGVVTKESLRPLTRGVVIDGKKTKP
                     ARYRIIRVEPDKNRSIVELTIHEGRHHQVKKMFEVVGHLVDKLSRTQFGSLDVRGLKP
                     GEARRLSKKEVSQLHHLASTRK"
     gene            48495..48773
                     /gene="yidD"
                     /locus_tag="TV191_000218"
     CDS             48495..48773
                     /gene="yidD"
                     /locus_tag="TV191_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEL1506770.1"
                     /translation="MIKALLIAPVRAYQKYISPLFPPSCRYQPTCSAYMITAIEKHGA
                     KGVLMGLTRLLRCHPFAAGGEDPVPDTFSLKRHFITHEKIQDFDQKTD"
     gene            48932..49480
                     /locus_tag="TV191_000219"
     CDS             48932..49480
                     /locus_tag="TV191_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEL1506771.1"
                     /translation="MKQEIINRQYREKDSQNHVVLFQPQIPQNTGNIARTCAATNTPL
                     HIIRPMGFPIDDRKMKRAGLDYWDKLDIRFYDHLDEFLAQCDGSLHVISKFADRVYSD
                     EAYNDRQSHYFLFGREDTGLPEPFMRQYADRALRIPMNDEHVRSLNVSNAVCMIVYEA
                     LRQQAFKGLELSHTYEHDKLKS"
BASE COUNT        14211 a         9201 c        11780 g        14426 t
ORIGIN      
        1 ccatagctca gttggtagta gcgcatgact gttaatcatg atgtcgtagg ttcgagtcct
       61 actggcggag tttggctcta tgtcaactat agtgggttga ctaacaacgg acatttagag
      121 aggatcagtt tggtgctctc ttttttgtgt actcaaaaag ctctatgatt tccacagtgg
      181 acttacctat tccagatggt atagagcctt gctttttagg ggatagtatg gtaggatagt
      241 aatagttaag aaaagcaccc ttagctcaac tggatagagt acctgactac gaatcaggcg
      301 gttagaggtt cgactcctct agggtgcata gcaaggcaac aggacatttc tgtcctgttg
      361 tttttttgtt tgtctcctta taataaggct actaagcatg aaaaggagaa agtataatga
      421 ctgatgattt agtgaggttg tttgataaga tcaagcctat tattatgaag ctaagacagc
      481 attattatat tcagctgtgg gagctagatg attggttaca ggaggggcgg ttgatcttgt
      541 atcggttatt ggtcacttat ccagaattga tagaggatga ggagaagcta tatcgttatt
      601 ttaagaccaa gttttcctct tatttgaagg acgtgttgcg gcagcaggag agtcagaagc
      661 gtcggtttca taagatggct tatgaggaga ttgggtcggt aggccatgcg ataccagcag
      721 gtggtttggg agtagatgat tatgtggctt atcagttgat tgtgaaggag gttgaggagc
      781 gattgacaga gggtgagctg tcgcagtttc gggctttgat caggggagag cggtttgagg
      841 ggagacgggc cttgcttcgc aagataggac cttactttca ggactttact ggtgagaaat
      901 aaaaggggtt accggaacga gattgaaagc gtttgctttg aaagaggaaa cctgctttcc
      961 cttctttttc atttgatttt gaatgctatt tctggtgaaa tatggtaaaa taaaaagtac
     1021 taattatttt ggagatgaaa tgagtgtcga tgattatagg ccgacctatg cggtagaggc
     1081 tgtttatgat ttaagagcaa atgatttact gcgtcaaggt attacagctg tcttggtgga
     1141 tttagataat accttaatcg cctgggataa tcctgatgga actccggagg ttcgtgcttg
     1201 gttagatgag atgacgattg cagatattag tgtggtggtt gtgtcaaata acacgtattc
     1261 acgtgtggag cgtgctgttt cgcggtttgg tgtggatttt attgctcgtg cgatgaagcc
     1321 ttttgcctat ggtattaata aggctattga tcgttatggc tttgatcgtg atgaggttat
     1381 tatggttggg gatcagctaa tgactgatat tagagctagt catcgggcag ggattaagtc
     1441 tgtcttagtg aagcccttag taacatcaga tgcttggaac actaaggtta atagatggcg
     1501 tgagcgtcgt gttttggcaa aattggaaga aaaatatgga aggctagtat atcaaaaagg
     1561 gatttaatgg aagaattatt ttgtatcggc tgcggtatcc agattcaaac aacaagaaag
     1621 caagaggctg gctttacacc tgctgctgct ttggtaaagg gaattgaagc tagggagatt
     1681 tactgtcaac gctgctttag attacgtcac tacaacgaca ttacagatgt tcatattact
     1741 gatgaagagt ttttgaggct gctccatgag gtgggagata gtgatgcctt ggtcgttaat
     1801 gtgattgaca tttttgattt taatggctca gttattccag gcttatcacg ctttgttgct
     1861 ggaaatgatg tgttattagt tgggaataaa aaggatattc ttccgaagtc tgttaaggac
     1921 agcaaggtga cacagtggtt gacagaaaga gctcatgagg agggcttgag acctcttgat
     1981 gtcctgctga cgagtgcgca gaataaatat gctattaaag agctgattga gcggatcgat
     2041 caattgcgcc aagggcgaga tgtctatgtt gttggggtga ctaatgttgg aaagtcgacc
     2101 ttgattaatg ccattattca ggaaattact ggggataagg atgtgattac aacgtcacgc
     2161 tttcctggga ccactcttga taaaatcgaa attcctttag atgatggtag ctttatcttt
     2221 gatactcctg gtattatcca tcgtcaccag atggctcact atttgtcagc taagaatttg
     2281 aagtttatca gccctaagaa ggaaattaag cctaaaacct accaattaaa tccggagcaa
     2341 acgctttttt taggtggctt ggcgcgattt gattttatta gtggtgaaag acaaggcttt
     2401 acagcttatt ttgataatca attgctcctc catcggacaa aattagaggg tgcagatgct
     2461 ttttatgaca agcaggcagg gcaactgctg actcctcctg ataaaaagga gcttgatgat
     2521 tttcctaggt tggttcgtca tgaatttctg ctggatcaaa aagtggacgt tgttttttct
     2581 ggtcttggtt ggattcgtgt taatgctaat aaggaaactg caactaaggt ggcggcttgg
     2641 gctcctgatg gtgttgcagt agtcgttcgc aaggcgatta tttaataaat aaaaagaaaa
     2701 gtggaataaa aatgcttaca agtaaacaaa gagccttttt aaaggctgag gcccatagtc
     2761 ttaaaccgat tgttcagatt ggtaaaaatg gcttgaatga tcagattaaa accagtattc
     2821 gtcaagcctt ggacgctaga gagctgatca aggttactct gttgcaaaat actgatgaaa
     2881 cgattcatga ggtggcagag attttagaag aggagattgg ctgtgatacg gttttaaaga
     2941 ttggtcggat ccttattttg tttaaggtgt cagctaaaaa agacaatatt ttgtttaagg
     3001 tgtcagctaa aaaagacaat cgcaagctat cagttaaggt caaatcgatc tagcgagagc
     3061 ttttgctagg ctaagacgtt taggtctgct gtgtcagtgc tgacaacatg agtaatggtg
     3121 atattttgga gaggttatgg ctttagaact tttgacgcct tttacgaggg tggaattaga
     3181 aatggaaaaa aaagatagca atcgcaagca ggttggtatc ttgggaggga attttaatcc
     3241 tgttcataat gctcatttag tggtggctga ccaggttcgt caacaattgg ggcttgatca
     3301 ggtgcttttg atgcctgagt ttaagcctcc gcatgttgac cacaaagaaa caattgatga
     3361 aaaacatagg cttcgtatgc tggagctggc tattcaggag acagaaggtc tagcgattga
     3421 agagattgag cttacacgtc aaggggttag ctatacctat gatacgatga agctgttaat
     3481 tgagcaaaat cctgacgtgg attattattt cattattggt gcggatatgg tagattattt
     3541 gccaaagtgg caccgtattg atgagttgat ccatatggtg cagtttgtcg gcgtgcaaag
     3601 gcctaaatac aaggctggta cctcttatcc ggttatctgg gtagatgttc ccttgctaga
     3661 tatttcctca agcatgattc gtgactttat ccaaagtgat cgtcagccta atcatttatt
     3721 accaaaggct gttttagact atattcataa agaaggcctg tatcaatgat gtatcaagat
     3781 tatgttggct atagacgtga tgagctgtta ggaaaaattg ctgagcagat gagcgataag
     3841 cgctttaagc atgttcttgg cgtggaaagg gctgctattc acttggcaga gcgttaccat
     3901 tgtgatccga ttaaggctgg gttagcagct ctactgcatg actatgccaa ggaatgtcct
     3961 gatgagcttt ttataagctt aattgacaaa tatcagctgg atcctgagct tcttaaatgg
     4021 aacaataata tttggcatgg tatggttggc atttataagc ttcaggaaga tttggggtta
     4081 aaagacaaag gcattttgcg ggcaattgag attcatactg ttggcgctgc tgagatgacg
     4141 atattggata aaattctgta cgttgcagat tatattgagg aaggtcgagt gtttcctttg
     4201 gtggacgaag ctaggagaat agcagagctt gatctagata aggcagttgc ctacgaaaca
     4261 gctcatacag ttgcttattt ggcatcgaag gctcagccga tttttccgca aaccattgat
     4321 acttacaatg cctttgtgca ttatttacat gaggaataaa atgagaaaag aagaactttt
     4381 agaaattgtg attaaggctg ctgatgaaaa gcgtgctgag gatatgctag ctcttgatct
     4441 ggctggctta acaagcctaa cggactattt tgttattgta acggcaacca atagtcgtca
     4501 gttggaggcg attgctgaca atattcgtga aagggttaag gaagcaagtg gtgatgctag
     4561 tcatgttgaa ggaaacagtc agactggttg ggtgctgctg gatttgaatg atgtggtcgt
     4621 gcatatcttc tcagaagatg agcgttatca ttataatctt gaaaagcttt ggcatgaggc
     4681 tccagctgtg gagcttagcc actatttagg ataaaaaagc agtcggctct gggctgtttt
     4741 ttacaataag aaacagaaag gaagttggca ttagaggcag gattgcctaa gaggtaagct
     4801 cttgtagtac ttgctgtgag acgtgttgac tgtatcaaat aatatgcaaa agaattatga
     4861 taccttcgca tcagtttatg atgccattat ggacgactca ctttatgata agtggacagc
     4921 gttttcgctt cgtcatttac ctaaaaacaa ggagcatcag aagcttttgg agctggcctg
     4981 tgggactggt attcaatcgg ttcgatttgc tcagtcaggc tttgaggtta ctggcttgga
     5041 tcttagtcag gaaatgctag aggttgctaa aaagcgagct caatcagcta agaagatcat
     5101 tacctttgtg caaggtaata tgctggatct gtcacaggtt ggatcgtttg atgtggtgac
     5161 ctgctattcg gattcgattt gttatatgca ggacgagatt gaggtgggtg atgtctttaa
     5221 agaggtctat caggttttga atgatggcgg tatttttatg tttgatgttc attctattta
     5281 tcagatggat cacctttttc ctggttattc ttaccatgaa aatgctgagg aatttgctat
     5341 ggtttgggat acctacaagg ctgaggctcc acattcagtg gtgcatgagc tgaccttttt
     5401 tattcaggct gaggacggcc attttttacg ctttgatgag gtacatgagg agcgtaccta
     5461 tgatatcttg acctacgata ttttgctgga gcaggctggc tttaagtctt tcaaggttta
     5521 tgcagatttt gaggatcagg agccaacaaa gacaagtaag cgctggtttt ttgttgcaca
     5581 aaaatagctg tggctaagac aggtcagcga gcggttttgt ggtttagtgg ctctgtattg
     5641 agtctgtggc aggtcttgat gataatagga atagatgcga aaggtaggac aatgttatga
     5701 ctgtcactgg tattattgct gaatttaacc cttttcatta tgggcatcag tacttactat
     5761 cacaggcaaa ggggctaaaa attgttgcga tgtcggggaa ttttgtgcag cgaggggagc
     5821 cggcacttgt ggataagtgg gtacgcgcgc aaatggcatt ggaaaatgga gctgaccttg
     5881 tggttgagct cccttttctg gtttctgttc aatctgcaga ttattttgct cagggagctg
     5941 tggatatctt gatgagactt ggaattgata cccttgcctt tgggactgag caattgcttg
     6001 attaccagaa gctgtctagg ctatatagtg aacaagcaga gcacatgact gcttatttgg
     6061 ccaccttacc tgatcatcta tcttatccac aaaaaacaca aagcatgtgg gaggcctttg
     6121 caggccttag cgctactggt gataggccaa accatctttt agcattatcc tatgtcaagg
     6181 ccagcgcagg aaaaaagctg caattgcagc cgattaagcg gctgggggca ggctttcatt
     6241 cagaagccaa ggatcaatgc ttgtcatcgg cgacagcaat tcgaaagcat atcgctgaca
     6301 gagcctttgt ggaaaaatca tcacctaatg cagctcttat tttgagggct cctcaggtga
     6361 cttgggagca ttattttccc tttttaaaat atcacattct gacagctcca gatttaacac
     6421 agttttttca ggttaatgat gagctagcta gtagaatcag cgcagctatt cggagtgtag
     6481 cgacggtaga tgagctagta gaggcggttg caaccaagca ctataccaag gcaagggtga
     6541 ggcgtgtgtt gacctatatc ttggttaagg ctgtggaagc cccattgcca gaaggcatac
     6601 atgttttggg cttttcaaaa aaaggtcagg ctcaccttaa aacaataaaa gcttctgtgc
     6661 cgctaatcag tcgtattgga gctaagcctt gggatcagtt gactcaacga gctgacactg
     6721 tttatcagct gggacatacg gatatgccag agcagacttg gggatgtgtg ccgataaggc
     6781 cagaggcgat gaattgagcg ttactagaag caaaccactg tctttgtatg acacgcttag
     6841 aggaccagca agagcttcta agaagttcgg gtaggcccta tagtcagttg gtaaaggtgt
     6901 tattagagta gttcaggtga ctctttgctg gtataaaggt cagatagact gcctttgctt
     6961 gctaagctgt ttttcattgc tgataagaag gatagttagc aagaactgtc agctcatgga
     7021 agcttatcat ttaagatcaa aaaagttaag tttgttcttg actctctccc tacgtgatag
     7081 tctatacttg ttgttgaggt ggaaatagcc atactagttg gtgctctttt gacctcacta
     7141 aggaggaata ccatgaaaac cgtaaaagag gttagtcaat tgacagggct tagtgtacgc
     7201 accttgcatg agataggcct gctgcctcct acaatggtgg gagaaaatgg ttatcgcttt
     7261 tatgatgctg ctgccttgag acgtctacag gacatcttac tgtttcgtga gctggcattt
     7321 cctctaaaaa cgattaaaca attgctggac agccctagct atgaccaaca agcagccctt
     7381 gctgctcaga ttaagatgct agagctacgc aaggctcatt tagaaaaggt tattgctcat
     7441 gctaggactt tacaaaaagg agaagaaacc atgacctttg acatttatag taagtcacag
     7501 ctagaagcct ttcaactaga ggctaaggag cgttggggag agacagaggc ctatatggct
     7561 tatgaggcca aagtcaatca gcctagcgca gagcagctta tcaaggatat gggggagatc
     7621 ttttcaatct ttggtcgtat gctggatcag cctgtagcag agctagcagt acagcagcag
     7681 gtaaaggctc tgcaggatta cattagtcaa cacttttacg attgctcaac tgagatctta
     7741 tcagctcttg gttgtatgta tcttgaggat gaccgcttta gagcagctat tgatcatatg
     7801 ggtggtgcag gaacggcagc ctttgtcagc cgagctatta gctattattg tcagcactaa
     7861 gctgctaagt gcatatcact ggctgctatt cctaatttac gaaccctttt gaaagtgcta
     7921 taatgataga gttaaagcta atttaactct gcttattcta aaaagagctt aatcaaaatt
     7981 gtattttaga ggagaatcca atgggacgta aatgggcaaa tattgttgca aaaaaaactg
     8041 ctaaagacgg tgcaacatca aaggtttatg ctaagtttgg tgttgaaatc tatgtggctg
     8101 ctaagcaagg agagcctgat cctgagttga atacagccct caagtttgtc attgatcggg
     8161 caaagcaggc acaggtgcca aagcatgtta ttgataaagc cattgataag gcaaagggta
     8221 atactgatga gacctttgtt gagggacgct atgagggctt tggaccaaat gggtcaatga
     8281 ttatcgtaga caccttgacg tcaaatgtga accgtacagc tgccaatgtt cgtgctgcct
     8341 atggtaaaaa tggtggtaat atgggagcgg ctggatcagt ttcttactta tttgataaaa
     8401 agggggttat cgtttttaag ggcgatgacg cagacagtat ttttgagttg ctcctagagg
     8461 ctgatgttga tgttgatgat gtagaggcag aagacggatc aattactgtt tatacagcac
     8521 caacagatct gcataaggct attcttgctc ttcgtgaatc aggtatatca gagtttcagg
     8581 tgactgagct tgagatgatt cctcagtctg aggtaactct tgagggggat gaccttgctg
     8641 tttttgaaaa gctggttgat gcccttgaag cagatgatga tgtgcaaaag gtctatcata
     8701 atgtagctga tgtctaagcc ctaagactat catgtaaaca gagccgagat ttctcggctc
     8761 tgttcatttt cctataatcg agctctgtag aggctgagta tgactatctg ccttttatgg
     8821 taacagctga cgtagtagct gatcgtcaca tggtgctgct ttagcagagt tcaatcatta
     8881 gtatcttatg ataaaaaatg ataaactaat cttatgaatc ataaaggagt agaggacaat
     8941 gacaataaaa cgttatttag gtttagctgg cttggccgta ctgtctgtgg gtatgctagc
     9001 ggcatgtggc acaaaggaaa aatcagcttc gagcacaaag gacacaccaa aagaggttat
     9061 ctttgcgaca gttggaacaa ctgccccctt ctcatttgaa aaggaaggac aattgacagg
     9121 ctatgacatc gaagtggcta aggctgtgtt taaagatgct gagaagtaca agcttcaatt
     9181 taagaaaaca gaatggtcat ctatttttac gggcttagac tctggaaaat atcaaatggg
     9241 cggcaacaat atttcataca ctaaggaacg ctcagtcaaa tatttgtttt cttatccaat
     9301 tggtgcaact ccgtcagtgc tagttgtgcc aaaggatagt gatatcaagt cttatgatga
     9361 tattaagggt cattcaacac aggtggtgca gggaacaacg actgctgctc agctaaaggc
     9421 cttcaacgaa gagcatgctg ataatcctgt tgagctaaag tttaccaacg aaaccatcac
     9481 tcaaatgcta accaatctga atgagggcaa ggctgatttt aagatttttg atgccccaac
     9541 ggttaatgct atcattgata atcaaggctt agatcacttg aaaacaattg agctggcaac
     9601 aagcgagcag ccctttatct actttatttt tagtcaagat caagaggagc tacaggcctt
     9661 tgtcaataag cgcttagagg agctgacagc tgatggcaca ctcagtaaaa ttgctaaaaa
     9721 gtatctaggt ggcgattatg ttccagctaa gcaggatttg aagcttccta cagcaaaatc
     9781 ctaaattggc tgaaagacca acaacgatat aagcgactat ttggcttaaa accaagctgt
     9841 tagaaggctt gcttttaagc ctttttaaat gcctttgttg cctactaggg cttttaaagt
     9901 aacctagtgt ctagggcagc agctattaag atctgttgcc ttatttcgag ggtggttttg
     9961 aggtaaaagg tctgtagtaa gagccttgac ttaattaatg cttgcttggc tagtctgtca
    10021 gttggtttag gtttggtgtt ttgactagag attatagcta atggctatac cttatcctaa
    10081 aatttaccaa tttgaatgcg agagctattt cgtataaaat aaactcattg aaaaaaagaa
    10141 attgaggaac aaaatatgaa tattaaaaaa gctgtcggct ttgttagcct tgctcttgct
    10201 tcaatagctc tagtagcctg ctctggtaag caggacgaca aaaatacctt gaccattggg
    10261 gtaatgacta aaacggcatc tgatcaagcc agatgggata agattgaaga gctgctgaaa
    10321 aaggataaga tcactctaaa gtataaagag ttcacagatt attctcagcc caacaaggca
    10381 gttgctaatg gtgaggttga tatcaattca ttccagcact ataacttttt ggataattgg
    10441 aataaggaaa ataaggcaga tttgaaggct attgctgaaa cctatatcag tccgattcat
    10501 ctcttttcag ggactagtca agacggtaag gctaaatacc agtcagtaga tgagcttcca
    10561 gatggtgcgc aaattgcagt gccaaacgat gcaacaaatg aaagccgtgc cctgtatgtg
    10621 cttcaagcag ccggcttgat caagctcaat gtgtcaggtg ataagctggc aaccattgca
    10681 aatattacag aaaataagaa aaagctagat attaaagaat tagatgcgag tcagacagca
    10741 cgtgccttga cgtcagctga tgccgctatt gttaataata gctatgccgt tcctgcgaaa
    10801 attgatttta aaacctctct ttttaaggaa aaggctgatg agaatgccaa gcaatggatt
    10861 aatatcattg ctgctcaaaa ggattgggaa aagtctgcta aggcagacgc gattaaggca
    10921 ttaatcaagg cctaccatac agatgctgtg aagaaggttg tggataaaac ctcaaatggt
    10981 gttgacgtcc ctgtatggta agggataata ggtaatatta gtaacaggag gattgaggcg
    11041 tgtgaagcac gccctttctt atattagggg gaaaacacat gacaaaaacg gatcagcagt
    11101 acttaacaag gctttgggag gatcagctca cacaggatta tcttgtgtcg ttggggcaat
    11161 tgattgccag taggtctatt tttgctcaag gtatcggctt agaagagaca gcagcctacc
    11221 taaaggagct gtttgctcag gctggtgctg aggctattgt tgataagact tatgcagctc
    11281 cctttgtcct agcacgcttt aatagctcta ggccagctgc taagacactg atattttaca
    11341 atcattacga tacagtgcca gcagatagtg atcaaaagtg gacgagtgat ccctttacct
    11401 taacagagcg tgatggctat ttgtttgcgc gcggcgttga tgatgacaag gggcatatca
    11461 ttgcgagatt gacggctgtc gtcaggtatc taaaggagca tgcagacctt ccgcttaata
    11521 ttgtctttat gatggaggga gctgaggagt cagcttcggt agatttagat cggtatctgg
    11581 ctaaatacgc agaccagcta aagggagcag agcttttgat ttgggagcag ggcattcgta
    11641 atgagcatga tcagcttgaa ataactggcg gcaataaggg gattttgacc tttgagatgt
    11701 cagtagatag tgctcgttgt gatattcatt ttaaatatgg tggtgttatc gagtcagcag
    11761 cctggtattt gcttcaggcc ctatcaagcc tgcggaacca tcgtggggaa ttgctggtgc
    11821 ctggtattta tcaaaaagtc gttccgccaa ctgagcgaga gctagattta gttgagacct
    11881 atgcaattga gaatgctcaa gctctaaaaa agctttacgg actggagctt cctatgttac
    11941 aatcagagcg tcgtcaattg ttagcagctt attactttca gccctccatt aacattcaag
    12001 ggctgtggac tggctatcaa ggacaaggag ttaagaccat cattccttca caggctactc
    12061 ctaaaatgga ggttcgtttg gttcctggct tagagcctga gtatgtcttt gatcagatta
    12121 ggtcttattt gctcaataag ggctttgacc agatcaagct gacctatact ttgggtgaga
    12181 tgagctatcg gagtgatctt tcatcgtctg ctattagtca gctgattgca gcagctcagc
    12241 ctttttaccc taaggggcta tctcttttgc cgacatcggc aggaacaggc cctatgcata
    12301 ctgtttttga agccctgcag gttccgattg ccgcttttgg cttagggcat tctaatagtt
    12361 gtgatcatgc aggtgatgaa aacattgcta ttgtagatta ttgtcggcat attgcattaa
    12421 tagaggagtt aataacatct tatgagtgaa ccaatgattc aattagatca tattgatatt
    12481 acctttcacc aaaaaaaacg tgtgattgaa gctgttaagg atgtaacgct tcatatcaac
    12541 caaggggata tttatggcat tgttggctat tctggtgctg gcaaatcaac cctagtgcgt
    12601 gtgattaacc tgctgcagca gccaacaaag ggaagcatta caattgatgg ggagctgacc
    12661 tttgatcaag gcaaggttca gctgtctgct aatagcctac gtgagaagcg tcgtgatatt
    12721 ggcatgattt ttcagcattt caatcttatg gcacaaaaaa cagctaagga aaatgttgcc
    12781 tttgctctgc gccattctcg attgcctaag gctgaaagag aaaggaaggt gactgagcta
    12841 ttagaattag taggcttatc tgagcgtgca gacaattatc cagcacagct gtctggtggt
    12901 caaaagcaga gggttgctat tgcgcgtgcc cttgccaatg accctaaaat attgatttct
    12961 gacgaggcca cctcagcgct agatcctaaa acgaccaagc agattctcgc tcttttgcag
    13021 gaattaaacc gcaggctagg cttaacgatt gtcatgatta cgcatgaaat gcagattgtc
    13081 aaggatattt gtcatcgtgt ggctgttatg cagcagggaa ccttgattga agaaggcagt
    13141 gttttggata tcttctcaaa tccaagagag cctttgacgc aggagtttat caagacagcg
    13201 actgggattg atgaggcact tgagaaaatt aaccagcagg atattgtcaa ggagctacca
    13261 gctaatgcta ttttagctca gctcaagtat gcagggacat cgactgacga gcctttactt
    13321 aaccagattt atcgccagtt tgaggtgacc gctaacattc tttatgggaa tattgaaatc
    13381 ttagatcagg taccagttgg tgagatgatt gttgtttttg aaggtgcagc agcaagtatt
    13441 gaggcggcag aaaaagcctt gcatgaggct ggcgtcgatg tcactatttt aaagagaggg
    13501 gcttaaatgt tagaattgtt tcaggcttat ttgccaaatg tttatgagct tggctggtct
    13561 ggtgatgctg gctggggagt agccatttgg aataccttgt acatgacgat cgttccattt
    13621 attgtaggtg gagctattgg tttatttatt ggtcttttgc tggtactgat ggggccagat
    13681 ggggtgattg aaaatcgact ggtttgttgg cttctagata agctcacgtc gatttttcgg
    13741 gctattccct ttgttatatt aattgctatc ctggcaagct ttacttatct gattatgggg
    13801 acaaccttgg gtgcaaccgc agctctggtg cctttgacct ttgcaacctt tccttttttt
    13861 gcgcgtcagg tccaggttgt tttttcagag cttgatagag gtgtgattga ggctgcacag
    13921 gcttcaggag ctaccttctg ggatattgtc agggtttatc tgagtgaggg cttaccagac
    13981 ctgattcgtg tgtcaacagt gaccttgatt tccttggttg gtgagacagc gatggcagga
    14041 gctattggtg ctggagggct tggtaatgtc gcgatttcct atggctataa ccgttttaac
    14101 aatgatgtga cgtgggttgc cacccttatt attctcttgc tgatctttgc gattcaattt
    14161 attggagaca gcctgacaag gcattttagt cacaaataat aaaactgctc agagctttat
    14221 tagctccaag cagtttttta atgtcatgat gctgtagggt gaagtccttt tgtcttgctg
    14281 atgatgagac ctaagacaaa gcctaggatg gaaaagctaa tccagcccat tgaaaattgg
    14341 ccgagtggaa ccaacctttc aaagaaatag gaaagaccat caggcaaggt aaagagcttg
    14401 gttagctgtg agagggtagc tagggcgtca tacaatgctg gaatgatggt aaggccaatc
    14461 gtcgttctgt agacaagagg ggcattgcca aatgactttt ggatcagaac aagaacaatc
    14521 aaatcgacag tcagtgggta caagaggtac aaaataggag atgaccaatt gataataact
    14581 gacaagccac cgaagtagaa aaaggcagat acaagggtaa atagagttgc ccaagcaaca
    14641 tgtgataccc ttggcattag cttgtggaaa tactctgcac ttgaggtgat aagaccggtt
    14701 gaggtggtca gacaggctag gaaaatcaca atcgcaagga aggcttgccc aatgctacct
    14761 aggtaaaatc gtgaggcgtg gcttaaaatt tgtcctccat tgacagcgct gttgtttagg
    14821 gtaaaatgcc catcaacaaa agggaaaaga gattgtgagg tcgcaccgat ccgtcccaca
    14881 aaaatataaa caaaggctag cagcaaaatg gcaatggccc cagagataag ggtgatttta
    14941 gtgatttcct gatcggtttt agcgccaaat tgcttggttg cttcaatgac taatatggca
    15001 aaaaccaagg aagctaaagc atccatagtg ccgtagcctt gaataagacc tgcaataaag
    15061 ggaacgtcct taaaggcatt gttgatacct gctccagcat taaaggcttc gccatagtct
    15121 ccagctgggt gaacaaagga ggcaatgatt aaaatagtaa tcacaaccaa tagcgtcggt
    15181 gtcagaaatt taccaatgct ttctgctagc ttgcttggtc taatagccaa aaagtaggat
    15241 aagccaaaaa atagcacagc atagatggct ttattgatga tgctatctcc taatatcggg
    15301 gcaatcccaa cagagaagga ggtagcgcct gttctaggaa tagcaaagaa aggaccaatg
    15361 gacaaataca ggattgatga gtaaaggata gcataccatt ttgaaattgg ccgagccagg
    15421 ctttcaacat catcagagcc tgaccttgca acagcaatga caccaagcaa gggtaaagac
    15481 acaccagtca agcaaaagcc aataatggac caagggatat tttgtcctga atagatgcca
    15541 agaaaggccg gataaatgag atttgctgca ccaaaaaaga gagcaaacag cataaagcca
    15601 ataacgatat agacattttt ttctttcatt gccttaataa gtctttcttt tgatataaat
    15661 ttgaagattc caataattta attgaaaact cttgaaaata ataacagttg ctattatacc
    15721 taagtttctg aaagtcgtca acaattatca gacgatagat caagctgaga cctaaaaaag
    15781 cgctgagggg tatctggata aagcagctta gcctttattt tacagctttt gagaggactt
    15841 gctcacctgc tgaatctcta atcaagcctt gctagaaaga gtggtccaag gcttggggag
    15901 ctttgatgag agatttgctg tcttattgat gaaagaatct gtcagctagc ttatgatggt
    15961 ggggctgcag cggtgtataa catccttgct tgatttgacg aataactaaa attatattat
    16021 gataaaaaac atctaacttg agcgaggata aataacatga aaagaattcg tgacttatgg
    16081 gtcaggacca acctgattaa aaaaatagga atcggggtcg ttataggact tcttttgggg
    16141 attttattgc ctgatgtgac agcgattggc attttggggc agctttttgt tggggcttta
    16201 aaggcgatag ctcctctctt ggtttttgcc ttggtggcac aagctatctc tcaccaaagg
    16261 tcaggacagc aaaccaatat gaccttgatt attgtgcttt atttgcttgg aacctttctg
    16321 gcggccttgg ttgctgttat tgctaattac ctatttcctc taaccttaac cttaaatact
    16381 ccggttaata ctgagctttc accaccacaa ggtattgttc aggtctttca gacgctttta
    16441 ttaaagctag tggataatcc tattaatgct ttagctactg ccaattatat tggtgtctta
    16501 gcttgggcat tgatctttgg cttagccctc aagtctgttc cttcagattt taagcatttg
    16561 atcaaaacag cggcagatgt gacctcacaa attgtcgttt ggattatcaa tgtcgcaccg
    16621 attggcatta tgggcttggt cttttcaact gtttctgaaa atggcattag cattttgtct
    16681 gattatgctc ttttaattct ggtcttggtg ggaacgatgc tctttgtagc gctagtggtt
    16741 aaccctttgc ttgcctttgt cctgactcat caaaatcctt atcctcttgt ttttagatgt
    16801 ttaaaggatt ctggccttac agcctttttc acaagaagct cggcagcaaa cattccagtc
    16861 aatttgcagc tatgtgagga cttgggacta agtcaggcga cctatttagt atctattccc
    16921 ctaggtgcaa tgattaatat gggaggagca gccatcacga tcaatgtttt gacacttgct
    16981 gctgtcaata cctttggtat tcagattgat tttctgactg ccctgctttt gagtgtggtt
    17041 gcggctatct cagcctgtgg cgcttctggt gttacaggag gctctctcct tcttattcca
    17101 gtggcatgta gcctttttgg gatctcaagt gatttggcta tgcaggttgt cggggttggc
    17161 tttattgttg gtgtgattca ggattcctgt gaaacagccc ttaattcatc aactgatgtc
    17221 ctctttacag ccattgctga aaatgccttc tggaagcaaa agaaggccta gccttataat
    17281 acagcttatt agtaaaaaaa gaggctggga caaaaagagc tgcactttag aaagtcttaa
    17341 cctaatatac tttatgacct agtctcatgc attaaaaaag cgaacaagtc tagttttcgg
    17401 aatctctgaa aactggctcc atgtcaactg tagtgggtga cttatagcta agcacgagag
    17461 gagacgaagg ttgtcttctc ttttgtgatg ttcaaagcga ggaagatgcg ttttttaggc
    17521 tctataatct ccacagtggc cttacccact acagaaatta tagagcctga aaactagact
    17581 tgttcgttta ttttaggtca gacttttgtc ccagacccgt tatgttattt gaggtagcct
    17641 aggtagtcaa acttttcaaa ggtatgatcg ttagcgatag caacaataat ggtgtcagcc
    17701 tcaagtggtt caaagggctg aacattggtg tctagggttt tgacctcttt ttgacgcatg
    17761 ccaataatat taagctcgta ttttcgacga acatcaagct ctgagagcga tttgccctcc
    17821 cagctcttag gaatggtgaa ttcgatcatg gaaatcccat gttctaggta gataatgctc
    17881 tcaatgtgat ggcgtaagag atttgaggcc actcgctttc cagagtctct ttcaggggtg
    17941 ataaccttgg ttgctccaat gccatataag acctcttcaa aaattttgtt tttagccttt
    18001 gcaataatgg ttggaacccc taatttttta cagtgcatga cagctagtac agaggactct
    18061 agattgtttc ctgatgcgat gacaactgtg tcacattgct caacccctac tgcgattaaa
    18121 aaatccttat cagtaatatc gccaacagct gccttggtcg ccaaatcagc aatttctttc
    18181 acgtggcttt ctctaatatc aatggcaatg acatcttggt catagttgct taattctctg
    18241 gcaacggtgc ggccaaaaat ccccaggcca agaacaccaa cagtttttcg ttttaacatg
    18301 atttctcctt aacccactaa aatatcagta gtggcatatt gaatggtttt ttctttacgt
    18361 tgaattagac taatcaaaac agtaattggt ccgacacgac caacaaacat cagcacaata
    18421 atgattaggc gtcctgcact tgataagtgc ggtgtgacgt ccattgatac cccaaccgtt
    18481 gcaatagctg aaatggattc aaataaaagc ggaatagggg cgatatctgg ctctacactt
    18541 agcagtaaaa tgtagccaat catcaagacc gcaaaaaaga aaatcaaaac agtcatggtt
    18601 tgcttaatgg tcttgttggc gatgatacgg ttacgaaagg ttacctcaga ttgaccggaa
    18661 agctctgcct taaacaataa aaaggtgatg gcagcagttg tgattttgat tcctccggca
    18721 gtaccacctg gagctccacc gataaccatc tgaatcatat aaagaatatt ggtaggagcc
    18781 aaggtatcat tataagaaat agtcgcaaag cctgcagttc tcatggttac cgtttggaaa
    18841 aaggacacca tcagctgctg cggtagattg tatctggcaa tagtattgag attgtccttt
    18901 tccaaaaacc atgataaaaa ggtacctaaa acaaggataa ctagggttgt ttgcagcact
    18961 aagcgtgact gattagaaaa ctttttaaag gtgatgccat agcagtgagg cctttcaaag
    19021 aagtattttt taaaggcagt gcctaaatca acccaaacag caaagccaag tccgccagaa
    19081 ataattaaga aggtgataat agcattgatg gtagggttta acacaaagtc ctttaagcta
    19141 gatgatccta gattatcaaa gcctgcatta caaaaggcag agacagccag aaagatactg
    19201 ttaaagatac catttttcca gccgaaacga gggataaagt cagtcatgat aaccaaggca
    19261 gcaaaggcct ccagtgagaa ggtgacctta taggcaaaaa agaggtattt ttttaagtcc
    19321 ttactgtcac cacgattgag ggcggattgg agcaaggttt gatcacttaa acgcattttg
    19381 cgcttgagtg caaaggtgct gaccgcaatc agagtgacca atccaagtcc gccaatttgc
    19441 atgagcatca tggcaattgt ctgaccaatg ccattgtaga catctgcaac aggaacgaca
    19501 gaaagtccag ttacacagac cattgacacc acgttgaaaa aatgatcgag gtaaaccgta
    19561 ttaggaccat tgctgtagtg ggtaaaaggc atggataaca agagactacc tatcaaaatg
    19621 acaatcgcaa agctaaaggt tagccgctgg gtcaccgata aggacttgaa aaatgagcgt
    19681 ttcatgattc ctcctaataa tatctcatac tatcatatca aaaatacatt aaaaaagcta
    19741 agcagtaacc tagccttaga ctgaagcagc cctgtttaca ataggccctt cctaacatgc
    19801 tccaaaagac aatagctttt tttgacatgt caggcttaag cttttagctc agagcttaaa
    19861 agtgctgagt aagattttat aaagtcttaa gggctttagt cattgttgcc acagtagaaa
    19921 acagaatggc gagctcactg cctagcctat gttttttctt gctaggcttc aaagaggctt
    19981 gatgttttga agcgtcaaaa gtaatcttga cagggttcta tatggctaat cgatatcact
    20041 caaggctagc acttagcttt tgtggtttga tcacatgatc attggctgtg gtcatagcgt
    20101 cagctccctc ctactagcct ctaatggcta ataggaggat caagggcaac aaaaaatgtt
    20161 cagacagcct ttaatcaagg ctgcctgaag cagcattcta tagcctctta caatggtttt
    20221 tattaggaat accggctttt cgagggtact tgtttggcgt ttcctttttc ttttcgacaa
    20281 gagtgatata gcggccatct ccattaggaa gttggtaggg ctggtgatca agcaccttag
    20341 caaaaagtag ctgaagtgcc tttttagctt cttctaattc ttggtccgct gcttgtgcct
    20401 ttaaagcaat cagttttccc ttgattttta aaaaaggaat ggtcaactca gacagaatct
    20461 gcatgcgggc aacagctcta gcagttacca aatcaaattg gccacgaaat tgcttgtctt
    20521 gtccaaaatc ctctgcccta ccatgataga aatgtactcc ctctaatcct agctctttag
    20581 caaggagctg aagaaaatgt atgcgcttat tgagagaatc aataatggta acatcaagct
    20641 ttggaaacat aattttcata ggaatgcttg ggaagcctgc tccagcccca atatctaaca
    20701 gcctgagagg ctcatttgga atatatccct gtaaaagcgg agcaacagag tcataaaagt
    20761 gcttgagata gacttcattt tcttcagtga tggctgttaa gttgatctta cggttccaat
    20821 caaccaaaag cttaaaataa gtgtcgaatt gttctttttg atgatttgtc agagcaaatc
    20881 ctgcttgctc caggacaagg taaaaggctt ggggtgtcat atatatcctc tgtttttaat
    20941 taattgctac tattttagca taaaatagca gaaaactgct gaaaagtccc ttcaatactt
    21001 gctattaaac tgaaaattgc tataattgag acacaaagat taaaggagaa ttacaatgcc
    21061 aatgttttta gtaatagtag cccttatcgg tgtgctggtt gtttggctga tggttagcta
    21121 taatggcctg gttaaagctc gtatgcatac aaaagaagct tggagtcaga ttgacgtgca
    21181 gctaaagcgt cgcaatgact tgattccaaa ccttgttgag acggtcaaag gctatgctaa
    21241 tcatgaagag aaaaccttag aaaagattac tagtcttaga tcacgtgtgg ctgatgctac
    21301 tacaccgcag gccacaatgg cagcctccaa tgaattgagc aagcaggtca ctagcctctt
    21361 tgcagttgca gagagctatc cagacttaaa ggccaatagt aatttcctaa aattgcaaga
    21421 ggaattaacc aatacagaaa ataaaatttc ttattcgcgt caattattta atacaacaac
    21481 atcgcattat aaccttaagc tagaaagctt tccgagcaat cttgtggcta aattgtttgg
    21541 cttcaagcca agtgagtttt tacaggttcc tgaagctgaa aaagaggttc caaaggtaga
    21601 ctttaccgtc tagtctaatg cggctaatca aggtcagaag aggacatcaa tgctttatca
    21661 acaaatttca caaaataaac gacgaactgt tatcctgctt tttgcctttt ttgtcttact
    21721 ggtagtgatt ggcgctgctg ctgggtattt actggctgac agctaccagc tgggggctgc
    21781 ttttgctctg attattggtg ctatttatgc ctttagcatg atttttcagt caaccagcct
    21841 cgttatggga atgaataagg ctaaggaaat cacagtaaac gatgctcctg atttctttca
    21901 tattgttgag gatatggctc tggttgctca gattccaatg ccaagagtat ttatcattga
    21961 tgatccctca ctaaacgcct ttgccacagg ctccagccct caaaatgcag ctgttgcggc
    22021 aaccactggt ctactaaagg tgatgaatcg tgaggagtta gaagcagtga ttgggcatga
    22081 agtcagccat attcgtaatt atgatattcg gatatccact attgcagttg ctttagctag
    22141 tgctgtcaca ctgatttcca gcattggggg gcgtatgatg tggtatagcg gtggcaggag
    22201 acgtgataac gatcgcaacg ataatggctt tggcgctatt atgctgattt tctcaatctt
    22261 gtcactgatc ttggctcctc ttgcggcctc tctggttcaa ttagccattt ctcgtcaaag
    22321 agagtatctg gcagatgcca gctctgtcgc gttaaccaga aatccagagg gcatgattag
    22381 ggctctacaa aagctaagca attcacagcc tatgactcat ccagtagatg atgctagcgc
    22441 agccttatac atcaatgagc ctagaaaaaa agaaaagctt agcgctttat ttagtaccca
    22501 tccgccgatt gaagatagaa ttgaacgctt gaagcatatg tgagagcttg agactagctc
    22561 agctctcatt tttactagcc ataatgttca gaaaacatca ttaattaatt gttttgaccc
    22621 ggacattttt taagactttt atggaaattt gggctatttt cataggggtt ttatggttaa
    22681 acatttgatt gttggcttgt caatacttat ttgtatccag acttaatgtt aaaaaaagtt
    22741 atgaatttgt cataaagcta ttgacaaatt cttgatatca tagtaaaaat agattagagt
    22801 tttattagga agtgttttat aggagaaagc atgttatctg tttcagatat tagaaagcga
    22861 ccggaaggca ttcgctttga gagagagtac gatgttaagg aagcgctgct tatacgtgat
    22921 ccgcaggtta tagatattaa taacgtcaga gcttcgggga gagctcagtt tgatgacggc
    22981 ttgtatctat tagagtatca gctgggctat cagattaccc tgccctcgag ccgttccatg
    23041 gcgcctgttg tcttagatga gatgcagacg gttcaggagc tgtttatcga ggaagcagat
    23101 gtggcaagta agcaggaaat ggttgatgaa aaccttgtct tagtcttatc agaggatcag
    23161 cttgaccttg aagagagtat tattgacaat attttgttgg cgattccctt gcaggtattg
    23221 acagaggctg aaaaggagtc acaaatcttg ccgacagggg aggattgggc agtcttaact
    23281 gaggagcaat accaggccca gcagaaggaa aaagcaaaag acaacagtcc ttttgcgggc
    23341 ttacagggtc tttttgatga gtaaaaataa aaattaaaga tgtctgtatt ttttatttga
    23401 aaaaagaaca gttgtctggt atactttata aatatacggc atattagtca ttttgatgac
    23461 taaatagcaa tacttgatta atacaaaatg gatgaatctt gtacatagct gataaggggc
    23521 tgtgatacag gaagtaagga ttggtgtaat gacaaagaaa attttaatta tcgaagatga
    23581 aaagaatctt gcaagatttg tttcgcttga gctacagcat gagggttacg aggtaaccgt
    23641 cgaggttaat ggtcgtgagg gcttggagac agccctagag aaggactttg acttaatcct
    23701 tcttgatttg atgcttcctg agatggacgg atttgaagtg acacgtcgat tgcaaacaga
    23761 aaaaacgact tacatcatga tgatgactgc gcgtgactct attatggacg ttgtagctgg
    23821 cttggatcgt ggtgctgacg attacatcgt gaagccattt gccattgagg aattgctggc
    23881 gcgtattcgt gctatcttcc gtcgtcagga cattgagtca gagaaaaaga ctcctagtca
    23941 aggcgtttac cgcgacttag tcttaaaccc tcaaaaccgc tctgtcaatc gcggtgatga
    24001 cgagatttca ctgactaagc gtgaatatga cctgcttaat attttgatga caaacatgaa
    24061 tcgtgtcatg actcgtgagg agctcttgtc taacgtttgg aaatatgacg aggctgttga
    24121 aactaacgtt gttgatgttt atattcgtta ccttcgtggg aagatcgata tccctgggaa
    24181 agagtcttac attcaaactg ttcgtggaat gggttatgtg attcgcgaga aataattgat
    24241 ggcaaagcag aaaaaatata agaaaacgtt accaaaacgt ttatcgaatc ttttgttcgt
    24301 tctcttcttt tgcattttct ctgcctttac cctactcgct tatatttcaa caaactactt
    24361 tttgttgaaa cgagaaaagc aaactatttt tcaggctgtt aacattgtta gagttcgtct
    24421 ctctgaggtg gactctaatt ttacgttaga gaatttagca gaggttctct ataaaaatga
    24481 cagaacgcat ttaaagattg atgacgcaaa tggtagtcgt attatcagaa gtgaacgaaa
    24541 tatcaccaac acgctcaatg ccaatgagga tatctatgtc tacaatgttg ataagcaaat
    24601 gatcttcaca acagatgacg aagaggcctc gccaggctta aatggaacta ttggtaaggt
    24661 aaccaaggac cacattgagg agcaatacaa gggcttttca atgactcaga aggtctactc
    24721 taataagaca gggaagtttg taggctatgt tcaggttttc catgacttgg aaaactacta
    24781 catgatcaga gcacgcctct tcttttggct tttggtggtt gagctctttg gggttggtct
    24841 ggcgtatttc attatcttaa ttgtcacacg caacttcttg aagcctctga acaatcttca
    24901 tgatgtgatg cggacaattt ccaaaaatcc agataatctg atgctgcgct cgggtatttc
    24961 ctcgggtgat gaaattgagg aattgtccgt tatttttgat aaaatgcttg ataagattga
    25021 gacgcataca cgattgcaat caagatttat tagtgacgtc agtcatgagc tgcgcacgcc
    25081 agttgccatt atcaaggggc atattggatt attgcagcgc tggggcaagg acgatagtgc
    25141 tattttagat gaaagcctca ctgcagctgc gcaagaggtt gaccgaatgg ctattatgat
    25201 caatgacatg cttgatatga tccgagtaca ggggtccttt gaagggcatc aaaatgatac
    25261 aactgtttta gagagctcta ttgagaccgt tgttggtaat tttagggtcc tgcgtgagga
    25321 ttttgatttt acctggtact ctgaaaatca aagaacccta gccaagattt ataaaaatca
    25381 ttttgagcag gctctgatga ttttgataga taatgcggtc aagtattcta ggaaggaaaa
    25441 gaaaatcgtc atagaattag cggttaatgc tagcaatgaa gctgtggtta aggtcaaaga
    25501 cagaggtgag gggatctcag aagaggatat taagcatatt tttgagcgct tctaccgcac
    25561 cgataggtcc agaaatcgaa ccagcaccca agcaggtctt gggattggct tatccatttt
    25621 aaagcaaatt gttgatggct atcatttaca tatggaggtt gagagtgagc taaataaagg
    25681 gtcggtcttt attttgcgga ttcccttagc tgatcatcaa ggctcatagc tgtatacctg
    25741 cctgagtatc tagtagatgc tcaggctttt gactgttcta atgtgtggtg tgatgatgag
    25801 gtgtttatca gggaaggagg gctcttggag gtaaacctga gtgcttgtct attcttttgt
    25861 tatccctaaa attatggtaa aatagggtat tagattaacg atagaattgg ggtgtttgcg
    25921 tgcgttgtcc gaaatgtaac tataataagt caagtgttgt tgatagtaga caggcagaag
    25981 atggcaatac gattcgtcgc cgcagagaat gcgaaagctg tcacacgcgc tttacaacct
    26041 ttgagcgctt agaagagctt ccattactag tgatcaaaaa ggacgggact agggagcagt
    26101 tttcaagaga taaaatctta aatggtgttg ttcaaagtgc ccaaaagcgt ccggtgtcaa
    26161 gtactgacat tgaaaatctc atttctcgca ttgagcagaa ggttcgtaca gcctatgaaa
    26221 atgaggtgtc aagtactgtt attggcaatc tggtgatgga ggaattagca gagcttgatg
    26281 agattaccta tgttcgtttt gctagtgtct ataaaagctt taaggattta gacgaaatcg
    26341 aagagctctt acagcagatt actaatcgcg ttagaggaaa aaagaagagc agtgtagatg
    26401 atgaagccta ttgatacctt ttcttatatt aagcataatc aggttcaata cgattcaagc
    26461 agcctgattc agttgtattt tcctattatt ggaaatgacg cagtggcagt ttatcagtat
    26521 ttggttcact tttttgatga tggctcagga gcccacaaat ttagtgatat tttaaaccat
    26581 ctgcagtttg gaatgaagcg cctagaggaa gccttggtga tgctgacagc tattgatttg
    26641 ctggtcttat atcagctgcc agatgcttat ttgataaaac tacatcagcc cttgggcagg
    26701 gaagcctttt taaataaccc aatttatcgt aggcttttag agcaaaagat tggagatgta
    26761 gcggttttgg agttgcaaat ggtgattccg aaccaggcta gaaacatctc aaagaccttt
    26821 tcagatgttt ttggaataga ctctcaggag cttaagcagc ctcagccatc aaagataaat
    26881 tttgatttag atagctttca gcagctaatg cggcgtgacg gtcttaggtt tgaggatcat
    26941 caaaaggacg ttatcagtct ttacagtatt tctgagcaat accacctaac ctggtttgac
    27001 acctatcagc tggctaaggc aacagcagtc ggcggcagca ttcgcccaga gcgcatgcta
    27061 gtcaagaagc agcaagaggg cgctcaaaaa acaagtgaat cgttctcacc agctgagcag
    27121 gttgttctta gagagtctaa gcaggacacg cctcttgtct ttttagagaa gatcaaaaaa
    27181 gctaggcgag ctagagtcac aaaggacgaa aaggaattgt tgctgactct agcccgcatg
    27241 aatttcttgg acgaggtcat caatattatg gtattatata ccttcaataa gaccaagtca
    27301 gctaatcttc acaagactta tctgatgaaa atggcaaatg attttgctta ccagcgggtt
    27361 ttaacagcgg aaactgctat tatcaagaca cgcgcctttg gtgagcgtaa gcagcaggca
    27421 aagtcacagc agtccaatgt gcctaagtgg agcaatccgg attatcaaga aaaaacaagt
    27481 caggaagaac aggcaaagct agagcagttt aagcaggctg ccttaaaaag gctggagaac
    27541 ctaggaaaga gtggtgacta gatggaaaag atcgggaaaa tggtagagca tttgggacag
    27601 gctagtcgtg tagctagtgc tgagctgatt gaggctatac ttgctgatca ggaggtggct
    27661 gagtttatca aggctcacca gctatctcag gcagaaataa agctgagttt atcaaagttc
    27721 aaccagtttt tagttgagcg ccggaaatac cagacaggtg atgagaccta tattgctaag
    27781 ggctatcagc ccattttggt catgaacgag ggctatgcag atgtgtctta cctagagaca
    27841 agagagcttg ttgaagccca aaggcaggca gctattgcag atcggattca tttggttagt
    27901 ctgccaagat cttatcgtag ggtttctttg tcagctgttg atgttaacaa tgccagtcgt
    27961 atgcaggtgt tttcagagct tttggatttt gttgagcagt atccagcggc agagcaaaag
    28021 ggtctctacc tttatggcga tatgggggtc gggaaatcct atctgatggc tgctatggca
    28081 catgaattgt ctgaaaaaaa gggtgtatca acaactcttc ttcattttcc tagctttacg
    28141 attgatgtta aaaatgccat ttcaaatggc tctgtcaaag aagagattga tgccatcaag
    28201 catgtccctg ttttaatttt agatgatatt ggtgcagagc aggcgacctc atgggtgcgt
    28261 gatgaggtgc tacaggttat tttgcagcat cgtatgctag aggatttgcc aacctttttc
    28321 acctctaatt acagctttgc agatttggag agaaaatggg caaagatcaa aggaaatgat
    28381 gagacctggc aggccaagcg tgttatggag cgtgtgcgtt atttagcacg tgaatgccat
    28441 ttagaagggg ttaatcgccg ccagggctag ctaaacgcta gctcaagcga tggataatga
    28501 gataaagaaa aggagaatca tggttttacc tacagttgcc attgttggac gtcctaatgt
    28561 tggaaagtcc acgttattta accgaattgc aggagagcgt atttctatag ttgaagacgt
    28621 cgaaggggtt actcgcgacc gcatttacac gactggtgag tggcttaacc gccaattttc
    28681 attgattgac acaggtggta ttgatgacgt tgatgctccc tttatggagc aaatcaagca
    28741 tcaggctcat attgcgatgg acgaggcaga tgttattgtc tttgtggttt ctggtaaaga
    28801 gggcgttact gatgcagacg aatatgtctc taagctcttg tatcgtacca acaagccagt
    28861 gattttggtt gtcaacaagg tggacaatcc agagatgcga aacgatattt atgattttta
    28921 ttctcttggc ttaggagatt ccttcccggt atcatcagtt catggtattg gtacgggtga
    28981 tgttttagat gctatcattg ataacctgcc gatagaagag ccagtagaaa acgacgatgt
    29041 gattcgcttt agcctaattg gacgtccaaa tgttggaaaa tcaagcctca ttaatgcgat
    29101 cctaggagaa gagcgtgtca ttgccagtcc tgttgctggt acgactcgtg atgcgattga
    29161 tacaagcttt accgatgaat ccggtcaagc ctataccatg attgataccg caggaatgcg
    29221 taagtccggc aaggtctatg aaaatactga aaaatactca gtgatgcgtg ccatgcgtgc
    29281 cattgaccga tcagatattg tgttaatggt tattaatgcc gaggagggca ttcgtgacta
    29341 tgataagcgg attgcaggct ttgcgcatga ggcaggtaag ggcatgatta tcgttgttaa
    29401 taagtgggac accatcgaaa aggataatca tacagtagct aggtgggagg ctgatattcg
    29461 tgatcaattt caatttttga cctacgcccc tattatcttt gtttctgccg ttacaaagca
    29521 gcgcttaaac aggcttcctg agttgattaa gcgtatcagt gatagtcaaa gccagcggat
    29581 ctcgtcagct attttaaacg atgtgattat ggatgctatt gcgatcaacc caaccccaac
    29641 ggataaggga cggcgtctaa agattttcta tgctacacag gtttctgtga agccgccaac
    29701 ctttgttgtt tttgtgaatg aagaagagct gatgcacttc tcttatctgc gctttctaga
    29761 aaaccagatt cgtgctgctt tcacctttga agggacacca atcaagctga ttgcgcgcaa
    29821 tcgcaaataa gcccttttat tactcttgtt agtattggaa gcagcgagtg ctgttgatgt
    29881 gcggtgtcta gaccttgtgt gtcaggactt ttgaccgacc aataagcctt accagaaatg
    29941 agaggctgct atccaaatag agcttaccag caagcaaggc gtgccaagca ttgatgtcac
    30001 atgataatca ttagccctag gctagtgatt ttttagtgct ttaaagccta tcagaacagc
    30061 tatatacagc tactcaaata tgttttaata gcctttaaga gagatttttg caggaaatct
    30121 aagctgaagt ttgttataat caaaggataa gcaaaaaggt gggagcagat atggctagat
    30181 taattccggg gcggattcgc aatcaaggca tcgagcttta tgagcaaggc ttggtgaaaa
    30241 tcatagatga caggactgac cttcttcgag cagaggtgga tacttatcag gttcaatatg
    30301 gtatcaatga tgaggatatt aggtgtcagt gtgattattt tgagcgaaag cagtattgcc
    30361 agcacattgc ggctctagaa tattttctga aaaataatca gaagggcaag tcgctctcag
    30421 agcagcttaa caaccagctg gaaagtaagg aggaaactaa aaagctgacc tcctttggta
    30481 gtcttttttt ggacagtttg cacatgaacg aggacgacac gaccaaatat aggcttttag
    30541 cttctggtgc taaaagtcct ttctcatctg attactggtg gagccttaag ataaatcgct
    30601 tgcccggaga gaaggcttat gttatccgcg atatcaaggc ctttattcat ttggtcaaag
    30661 ttgagggctt ttaccagatt ggaaagaatt actttgagtc tctttccata ttgcagtttg
    30721 atcaggctag tcaggagctg attcgttttc tttggcgttt atcaacgcat tcagataagt
    30781 tagattacga atggctattt cctaaccacg ctcgtcatct tcggttaccg gcaggctttt
    30841 ttgaggaggg cattgacctg ctgacggggc tttacgagtt ttcatttgag acctcctctc
    30901 aaacctattc tcatctttat gttcgacctc tggaggcaga ggctggtctc tttcagttta
    30961 cagttgatgt tcatcgcagc tctattgagc tttacattaa ggaaaaaaat atagagtatt
    31021 ttttcaataa tgaatacctg ctatacatga acacctttta ccacctgagc ctgaagcagc
    31081 aaaaaatggt tcaagctatt cgcagcctgc ctattgaggc cgatttggcc aagcacattc
    31141 attttgatct tgatgatcag gctaagctgg cagctagctt gctggaattt cgagagcttg
    31201 gtcaggtgaa ggctcctaaa agctttgata ttagagattt ccaagtgact tttgtctttg
    31261 atattactga aaaaggtgag ttgacctctc agctgatttt tgactatggg agcattcaga
    31321 tcagtgataa ggcaagctta gaccagctcc cctttgctag ccattataaa aaagaaagca
    31381 gtatttatcg tgccttgaag cgctttgggc tttctccgca gttttttgct aagaaagcct
    31441 tgactgaccc caaggactgg tatcgctttt ttacagaagc tgttccttat tttgaaagtc
    31501 taggtagggt tcagctttcc tctaagctcc aagatcagcg cttaatggaa agccctcagc
    31561 ttacagtcaa acgtgaggga ggtcttttag atatttcctt tgatttttca acggtttgtc
    31621 agactgatat tgaaaaggct ttggccactt tgtttagtga tcgctcttat tttgtcaatc
    31681 agtcaggcaa gctggtcgtt tttgatgaag agacacaaaa aatcagccgt agcttacagg
    31741 aactaagagc taagcagctg gcaaatggtc acctccagct agaaggaata gctgccaccc
    31801 agctgtctca tctattttcg gatctgtctt ctgttcattt ttctgaggag ctagagaccc
    31861 taatcaagga cctgcagcac ccggatcgct ttgagctggg agagctggcc gttaaggcca
    31921 aggtgagaga ttatcagctg cagggcatca aatggctctc tgtgcttgat aagtatggct
    31981 ttggtggtat cttggcagat gatatgggct tgggcaagac actgcaaatc attgcctttt
    32041 tatcaagcag gctaaccgag acctccaagg tgcttatctt ggcaccctct agcttgattt
    32101 acaattggtt agatgagttt agtaaatttg cccctcagat agatgctgct gtatcctacg
    32161 ggctaaagcc ggcacgagat gctcttattc aagaaggaca tcaggtgacg attaccagct
    32221 attcttcctt taggcaagat ttagaaacct atcaggcaaa tgattatgat tatttaatct
    32281 tagatgaggc gcagatgatt aaaaatgccc agaccaagat tgctcagagc ctgcgtgcct
    32341 ttgacgtgaa gaattgcttt gctttatctg gtacgccgat tgaaaataag ctgcttgaaa
    32401 tctggtccat ttttcaaatt gttctgccag gcctgctgcc atctaaaaaa gcctttttga
    32461 aaatggaggc cagagacgtt tctcgctata ttaagccctt tgtcatgcga cgcaaaaaag
    32521 aggaggtctt gccagagcta ccagaattaa tcgagatgaa ttattacaat gagatgtccg
    32581 atggtcaaaa agcgatttat ctggcacagc taaggcagat gcaggagcgg ctgtctgctg
    32641 caactgatga tgatattaat cgcagtaagc tggaaatcct gtctggtatc acacgtctaa
    32701 ggcaaatctg tgatactcct agcctgttta tggattatca aggaggaagc ggtaagctag
    32761 acaatctaag aaccttgctg ctgcaaatta aagaaaacgg tcatagggct ttgctgtttt
    32821 cacaatttaa gggcatgctg gctcttgtca agcaggaaat ggatcagctt ggcttatcat
    32881 cttataccat aacaggctca acaccggcca atgaccgtca agaaatgaca cgtgccttca
    32941 ataatggctc aaaggacgcc tttttgattt ccttaaaggc cggtggtgtt ggactcaatt
    33001 taacaggtgc tgatactgtt attttgattg atctatggtg gaacccagct gtagaaatgc
    33061 aggccattag tcgtgctcat cgtattggtc aggaggacaa tgtagaggtt taccggttga
    33121 ttacccgcgg aacaattgag gaaaaaatac tggagcttca ggaaaataag cgtcatctga
    33181 ttaccactgt tttagatggc aaacaaggcc tagcaagcat gtctgtcgag gagatcaaag
    33241 aaatccttgg tcttcagccc tagcatgtat ggcttttagc acacgctctt aagcctatca
    33301 gctaaaggct agtgtctgtt ctctataaca aataaggcaa gagaatagag gtgatgagct
    33361 agtcacatca tttttgcttt gctgcctttc tttttaggaa ttactttgaa aaataggatt
    33421 atttagttta taatagggaa tgctatagga aggagagtga gatagaatga caaagcatgc
    33481 gtttcctctg gttgcagatg gtgagcctat tattgagtca gctaggcaga tggctttata
    33541 tgaaaacgaa gatttgatca caaatattgc tggcagctat caagataaac attacgacga
    33601 catcataaga gaccatcaat ttgctgagaa gactcctgtc gtctctaaag gatcccttca
    33661 tcattctcca gttgtcgatg aagatcatag ctacgctcaa aaggccagaa ggcaagcaaa
    33721 gcaggatgtc aaagaaaaaa gacaggctta tattgctaaa aatatggctt atagcccaaa
    33781 gcaggcaagc aagaaaggtc aaagtggggc cttctcttct aaaaaaccag cgacagaatt
    33841 gagccgtttt acagagaaat taaaccaaga gtcttatatt ttagctgagc ttcctcgtca
    33901 atataaggag ccgcaaaata ccagccaagc agctgtcaaa aaaaataatt atgacttttt
    33961 gaagcgcagc caaatctaca atcatcaaga agacagagat catcgtgaaa agaccattgc
    34021 tcaagagcta aacctgagtc gctttgaaga tattaagtaa gctttataca gccttatgtc
    34081 tgtcaacatt aaaaggagtt aacatgtcaa aaacctatca ttttatcgga attaaaggat
    34141 ctggaatgag tgccttagcc ctgctgctcc atcaaatggg gcataaggtt caaggcagtg
    34201 atgtggagaa gtattatttc acacaaagag gcctagagca agcaggcatt accattttgc
    34261 cctttagcga agataatatt tctccggata tggagctgat agcaggtaat gcttttcgtg
    34321 aggacaacaa tagcgaggtt gcttatgcga tgcgtcatca gctgcccttt aaacgctacc
    34381 atgagttttt aggtgagttt atgaagcagt ttactagtct tggtgtagcc ggtgctcatg
    34441 ggaaaacctc taccacaggc ttgttgtcac atgtgctcaa gcacatgacg gctacttctt
    34501 atttgattgg tgatggtact gggcatgggg ctgccgatgc tcgttatttt gtgtttgaat
    34561 cagatgagta cgagcgtcac tttatgcctt atcacccgga atattctatt atcactaata
    34621 ttgattttga tcaccctgat tattttacag gccttgatga tgtgttcaat gcctttaatg
    34681 actatgctaa gcaggtgaaa aaggctcttt ttgtttacgg tgaagatgag gaattaagaa
    34741 agattagctc tcctgcaccg atttactatt atggctttga ggacactgat gatttcgtag
    34801 cctttgatat cacacgcacg acaaatggct cagactttaa ggtaaagcac aagggtcatg
    34861 ctattggtca gtttcatgtt ccagcctatg ggcgtcacaa tattttaaat gctactgcgg
    34921 tgattgctaa tttatttatt gcaggctttg atatgaagct tgttgcagag catctgaaga
    34981 gcttttcagg ggtgaagcgt cgttttactg aaaaggtgat caatgacact attattattg
    35041 atgactttgc tcatcaccca acagaaatca ttgcaacgct tgatgctgct aggcaaaaat
    35101 accctaataa ggaaatcatc gctatttttc agccacacac ctttacaagg accattgctt
    35161 tgctagatga ctttgcccat gccctaaatg aggctgacag tgtttatcta gcgcctatct
    35221 acggctcagc gcgtgaggtt gataagggtg atgtcaaggt ggaggatcta gcggctaggg
    35281 ttgagcgccc agccaaggtc atctcagttg acaatgtatc gccgctgctg gatcatgata
    35341 atgcagtcta tgtttttatg ggagcaggtg atattcagtt gtatgaacgc tcgtttgaag
    35401 agctgctggc taacttaact aaaaataatc aatgattaag cgacctgcct taggcaggtt
    35461 ttctcgtcgt aaaggaggac ctatgctaat tagacatgtg aatcagactg actgggagat
    35521 tattgctgat atcgaacagg ccaatttttc tccccaagag gctgtagcag ccaatgtgat
    35581 aaaagagcgt gcagagctta tttcggatac ctttcttgtg gctgttatcg ccaatcagtt
    35641 tgtcggctat atcgaaggac ctgtcattgc tgagccaagg cttgaggatc acctatttca
    35701 tggtgtgacc aagaatccag caagaggtgg ctatatagcc attaccagtc tttctgttgc
    35761 tcctggatac caaaagcagg ggattggcac agctctctta gctgcaatga aggatttagc
    35821 agttgcacag gatcggctgg gtatcatact tacctgtcat gactatttga ttccttacta
    35881 tgagatgaat ggttttcaag atcaaggcct gtcagcttca aagcatggtg gctctgtttg
    35941 gtatcaaatg ctatggcagc cataggaagg ctattaaagc ttagcatgta ttaagaatta
    36001 gtaacaaaag ggggatttta ttgcatttat agtgcaatta ggatataatg gcggttgatt
    36061 aagtttagga ggaatggctt tgactgattt taaagatgat gagcaaagac gtcagcagca
    36121 aaaaagcttc aaagaaaaga ttctagccga attagaaaaa gcaaatcaga ttagaaaaga
    36181 aaaagaagaa gagcttttta aaaaggatct agaggttcaa gaggctgcta gaagaacagc
    36241 tcagctttat gcagaatata aaagacaaga agcactaagc aataacccca aacaagcgtc
    36301 tgatatagca gctgcgtcgc aagagacgac ctcaacggct tcaacagccc acacctctgc
    36361 gattaagcta gaagagacag cagtagctac tggggatcaa gcattgtcgc caccagagga
    36421 gcctgcattg agtgaaagcc tgcttaagga agaggcaagt gtcgaaggtc agactaagaa
    36481 gggtggtcca gtgagaagaa aaacaagtaa gcgccagcag acagatcgaa tggccaaaaa
    36541 aatttcgaca gtactgatat cgtcgattgt cgctattatt gtggtgattg gcctcgcagg
    36601 gacagcctat gtgtatagtg cccttaaccc tgttgacaaa aatagcgatg actttgttca
    36661 ggttgaaatc ccagccggct caggcaataa gcttattggg cagatccttg aaaaagaggg
    36721 gctgatcaaa aatagtaccg tctttagctt ttacactaag tttaaaaatt tcactaattt
    36781 tcaaagtggc tactacaacc tacaaaagag catgagccta gaagacattg cccaggcctt
    36841 acaagagggt ggcacagcag agcctacaaa gccagtacta ggaaaaattt taattccaga
    36901 gggctatacc attaagcaaa ttgctaaggc catagaaact aatagtaggg caaagaatcg
    36961 tagcaaggct aaaacaccat ttcactcaaa ggatttcttg aatttggtga caagtgatgc
    37021 ctttattcaa gagatggcta aaaaatatcc gaaattgcta ggagatcttc caagcaagga
    37081 agtagctact tatcagctag aaggctacct tttccctgcg acctataatt attataagga
    37141 aacaacacta aaagaccttg cagaggaaat gattgcagcg gcaaatgcaa acctagcgcc
    37201 ttattatgag gcgattgcag ctagtggcaa gacagttaat gaggtgctga ctttggcctc
    37261 cttagttgaa aaggaaggct ctactgatga cgatcggcgt caaattgcca gcgtatttta
    37321 caatcgctta aataatggca tggccttaca gtctaacatt gctatattgt atgcaatggg
    37381 taaattggga gaaaagacaa ccttagcaga ggacgctgct attgacacaa ccattaattc
    37441 tccttataat gtttatatca atactggctt aatgcctggt ccagttgata gtccagggct
    37501 tgcagctatt gaggcgacta tcaatccagc ggcaacagat tacgtttatt ttgtagccga
    37561 tgtgcgtact ggtgaggttt attatgcaaa aacatttgaa gagcactctg caaatgttga
    37621 aaaatatgtt aacagtcaaa ttcagtaagg acaaacatgg tgctttagca tcatgtttgt
    37681 gtttctgatt cgtcaaaaga aaaaggaaaa gagaaagata atggcagaaa agacttatcc
    37741 aatgacagca gcagaaaaag aacagcttga aaaggaatta gaagagctaa aattagttcg
    37801 tcgtccagag gttgttgagc gcataaaaat cgctcgttcg tatggagacc tttctgaaaa
    37861 ctctgaatac gatgctgcta aagatgagca ggcttttgtt gagggacaaa tctcaacctt
    37921 ggagacaaag attcgctatg ctgagattat tgatagcgat gctgttgcca aggacgaggt
    37981 ggcgattggt aagacagttg ttgtccagga ggttggcaca caaacaacag acacttatca
    38041 tattgtcggt gcggcaggag cagatatttt ttctggaaag atttcaaacg agagtccaat
    38101 tgcacaggcc ttgattggta agaaaacagg agataaggtt aagattgagt ctccagcagc
    38161 tacctatgag gttactatca tcagcgttga caaaacacaa taagacttat ctgactatca
    38221 gtgcagtgtc ctgatagtct ttttagtggc ttgcttttta atatcagttg ttgtggtcta
    38281 ttaaaaagag ctgcacttta gaaagtttta actaagatac tttatgacct agtctcatac
    38341 attaaaaaag cgaacaggtc taattttcgg aatccctgaa aattagacct gttcgtttgt
    38401 tttatcttga gtcagacttt tgtcacagac tcttttagct atcttagcga cgcttttttt
    38461 gtttaccggc gtttcggttt aacttagtcc tcttgcttgt gctaagggct tgcttttcag
    38521 ctgtaacgtc cttgcgtggc tggtgagatt tataggcctt aggagggttc tttgcgaact
    38581 cctctgcaat ttgcttgcgg agccttggtt ttaaaaggta ggttgtgatc aattgctgaa
    38641 tgatactaaa gaaaccacca actagccaat acaagcctaa tccggcaggc aggtaaaacg
    38701 acatgacaat catcataatt ggcatggtgt acagcatggc tttcatttgt tcacgttgct
    38761 cctcagggac tgccatcatt gacagccagg attgaacgaa gtataaagcc gcaattacag
    38821 ctgtaagcaa gacgctgcga tgccccaggt caatgcccat aaaggtactt gttgagactc
    38881 ccttggtaaa ttggaccgca acatacatgg cagaaaagaa aggcatttga atcagcagtg
    38941 gcaaacagcc tataccgcct agcgggttga ctccattttc acgctgggcc gccattaatt
    39001 ctgtttgggc tgccattttt tcttcagtgc ttgtagcgtt tttgatgcgt tgattaattg
    39061 gctcaaaaaa aggctttagg taggccattt tttctgattg gtagcttgcc ttccatgatt
    39121 ggtagagccc aagtggtagg ataatcgttc taacaataat agttacaaca atgatggcaa
    39181 gaccatagcc tagggcggtg ctgttagcaa agtaatcaat gagaaaggaa acgggctttc
    39241 caaggtaatc ccaaatgatg ccctccgggt gccccttggc gtctctgccg acacaccctg
    39301 tcaatgtcag taggaccgat aaggcaagtc ctgagaaaag tatgcgattc gttttgagtt
    39361 tcaatgtgtt tgtcctttaa tttttaatat acctaaccat tttactgttt ttttgagaaa
    39421 ttaacaatag ttctacagta ggatttttaa ttgctgatcc taaaatcatg gaaatcctca
    39481 aagtgagatg gattaacatc aacataggtc acctttgccc atttagaagg tccttttctg
    39541 atttcctgga taaagcgcgt catctttgca gggtcactag cctgtgctaa aatctcaaca
    39601 gtcccatcac tattgttcca cacgcggccg taaatatcac caatttccaa agctagtgcg
    39661 taggttgaat agcgaaagcc aacaccctgc accctgcctg aaacgattag tctgaccttt
    39721 ttcataagtc acctcttttc tttttattat agcatagata gcttataaat actaaaagtt
    39781 gtcatggagc aggcagccaa aggataggca aagactgcaa gtgggctatc tgctgaggta
    39841 aacaataggt cttagtgcag caaggctatg tttatggtta gctctccttc ttgtcttcta
    39901 aaaaggaaag ctaatgggct tacgacacct gataagggga gaaagctcct tttaggctga
    39961 tagccttctg atggttttta tgcaaaagag tgaacaattt tgtgatataa taagaccatg
    40021 attatcacat caaaagcaaa ccatttgatt aagcaggcta agaaattact gcaaaaaaag
    40081 catcgcaagc actcttactt gattgagggc tggcacctat ttgaggaggc tcagagatct
    40141 gggcaggaat tgatacatat ttttgttctg gaggaaatgg cagagcgctt atcaggcttt
    40201 gatcaggttg tcatcgtcag tccagagatt ctaaaggagc tgacgagctc tcccaatcca
    40261 cagggcatta ttgctgaggt taagctttgt caacaggcct taccgactag ctatgctgga
    40321 aaatatttga ttttagagga cattcaggat ccaggcaatc tagggacaat cattagaaca
    40381 gcggacgcag caaagtttga tggggtgttt ttgtctgaga agtctgcgga tgtctacaat
    40441 caaaaaactc tacgctccat gcagggcagt cattttcacc tgccgatttg gcgaacggat
    40501 atttatcagg tcagtcaggt gatgcagcag caaaaaatac cagtgctagc aacgaccttg
    40561 tctcaggatt cgattgatta caaggacctc tcagctagga gcagccttgc ccttgtttta
    40621 ggaaatgaag gtcagggcat tagtcctgag atggcagctt tggctgatca gctgattcat
    40681 attagcatgc ctggacaagc tgaaagctta aatgttgcag ttgcagcagg aatcctcatt
    40741 ttcagcctaa tttaagctag tatggtataa taatgatgtg aggtgattag tgtatgcatt
    40801 atacagaaga tacagaatac atggagcatg ttggtcattt gattgctcac cctcgctttc
    40861 aaaggcttgg agatattgtt cagcatcacc attctactcg cttagagcac tctgtcaatg
    40921 tttcttattc tagctatagg ctggcaaaga ggcttggctt agacgccaag agtaccgcac
    40981 gaggtggctt gctacacgat ttcttttatt atgattggcg agtaaccaag tttaacaagg
    41041 gacacgcttg ggtgcaccct agaattgctg ttcgaaatgc taaaaaatta acagcactca
    41101 acaaaaaaga agaggatatt atcctaaagc atatgtgggg agctactatt gcttttcctc
    41161 gctataagga aagctatatt gttacctttg ttgataaata ttgggcggtc aaggaggcca
    41221 tgacgccgct gcgtcaaaaa tggacgaacc gtcgcttcct gcgtcgaaag acgcttcaaa
    41281 gtcacaatca ttaagtaaaa aaaggagtta tgatgaacga taatgttatt tacacacagt
    41341 ctgacgcagg cttgagccat ttttttgcca aggtctatag cctggttggt atgggagttg
    41401 ggctttctgc ctttgtttct tatttgatgc tgtttccatt taggcaaaat ttagtctcga
    41461 ttgttcttga tcatcctatg gtctattatg gggcggctat tgttgagctt gtactggttt
    41521 ttgttgctag tggtgctgca cgtcgcaata caccagcagc tttaccctta tttcttgtct
    41581 attcagcctt aaatggcttt accttgagct tcattattgc agcttatgcg caaacaacgg
    41641 tgctacaggc ctttatctca tcggcagctg ttttctttgc tatgtcactg cttggtgtta
    41701 aggttaagcg tgatctgtca ggtattcgaa aggccatgtt tgcagccttg attgggatta
    41761 tcgtggctag tctggtaaat ctctttatcg gtagtgacct gatgagctat gtgatcagcc
    41821 ttatttcagt gttgatcttt tctggcttga ttgcttcaga caatcagatg atcaagcagg
    41881 tctaccaagc ctctaacggt caggttggtg acggctgggc tgtcgctatg gctcttagct
    41941 tatacctaga ctttatcaac ctctttatca gtctacttcg tctcttggga agaaatgact
    42001 aatagctatt ttaagcgcag ctgctgattg tcacttaatc gctattacga gaaatcagcg
    42061 aagctgcagg tgttaccttt tgttagaaaa gagtggctgc tgctagtaag aaagtagctg
    42121 ctaggagagc ctgatgagcg tgactgtcaa ggaaggccag ttactattgc taccatctag
    42181 ggaaggtacc aaaaaaagtc aagaagcggg cccaagggct cgtttttgtt tgcttgattt
    42241 gtggtaaagt gcttcaaacc aagcctatat ctagtctgat agctcttatc agctgacaac
    42301 atcatattta caatgcctgt tggtgtagat ttgtaaagca tgctcttttt tggtataatg
    42361 agaggaacaa aaaatcgagg agaatatcta tcaatatgtc tacagctatc tggatattat
    42421 taatcattgt tgctcttaca gccggtcttt ttggtgggat ttttattgcc cgcaagcaaa
    42481 ttgaaaagga aattggagag cacccacgat taacgcctga ggccattcgt gaaatgatga
    42541 gtcaaatggg tcaaaaacca agtgaagcga aaattcaaca aacttaccgc aacattgtca
    42601 agcaatcaaa agccgcaatg actaagggta aaaaataggt tacggattag aaatcgtggt
    42661 ttctaagcaa tagctaagag tgaacagtct ttgatgttaa aagcttgttt agagcttgca
    42721 ttgtcagtta gaggtgtcaa ctgttcaggg gttaacaata gactcagttg gctcttacca
    42781 gctgagtttt ttatgcttca atgaggaaat aatcgttatg gacaatagac caattggttt
    42841 tttagattct ggtgtaggag gcttaactgt tgttagtgag ctgatgcgtc agcttcccca
    42901 tgaaaaaatc atttatattg gtgattcagc aagagctcct tatggtccta gacctgctga
    42961 acaaatcaga gaatatacct gggagttggt tcgtttttta ttaacgaaac atgtcaagat
    43021 gattgtcttt gcttgtaaca ctgcaacagc tgttgcttgg gaggaggtca aggaggcttt
    43081 ggatattcct gttttgggcg ttatcctgcc gggcgctagc gcagctatca aggctactag
    43141 tggaggaaag gttggtgtta ttggcacatc aatgactatt tcttcaggca tttaccagga
    43201 aaagatccag ttgctggctc ccactgttca ggtaactagc ctagcctgtc ctagatttgt
    43261 tcctattgtg gagtccaatg agataagctc aagtgtggcc aagaaaattg tctatgaaac
    43321 cttggctccc ttagttggaa agatagatac ccttgttttg ggctgcaccc attatcctct
    43381 tcttaggacg attatccaaa atgtgctggg accacaggtt aaattgattg atagtggggc
    43441 agagtgtgtg cgtgatattt ctgttctttt aaattatttt gagattaatg gcagtcgaga
    43501 tgatgaacat aggcgtcatc atttttacac tacagccggc tcagacagct ttcaagcaat
    43561 tgcctcagcc tggctaaatc aaacgataga tgtggagcat gtgaccttat gagtgataac
    43621 atttatgaat acaaggataa agacaattgg tttattggca agatgacagg ccataattta
    43681 atggctggct ggggggttaa ccatgagctt attgccaaaa tagacgatat gttaggtgcg
    43741 attgctggtg atgtggattg ggaaagtccg gtcggttatg atgtgactgt tattcgttac
    43801 gcctcccctt ttgccttgat tagctttgtt gttggcatga tcaatcagaa agccaatcga
    43861 gcccttaagg ttgttcggca ctcaggtgcg attttagtga ccgaaaacga gcgattgctt
    43921 gctgtgcata tgccagatga tggcgtccct gtggctgact tctttggtca acaggcagat
    43981 ggctttgggg atacgatttt gattgcgact cgaaatgaag gcaagaccaa ggaatttcgc
    44041 cggctttttg gtgatatggg atatcgcgtt gaaaatctca atgattaccc agagcttcca
    44101 gatgtggcag aaaccggggt cacctttgag gaaaatgccc gcctaaaagc agaaaccatt
    44161 tcaaggctta ctggaaagat ggttctggca gatgattcag ggctcaaggt ggatatttta
    44221 ggtggcttac ctggggtctg gtcagctcgt ttttcgggcc ctgatgctac tgatgagact
    44281 aataatgcta agctattgca tgagctggca atggtatttg atcaaaagga tcgctctgct
    44341 caatttcata cgaccttggt ggttgctgca cctggtaaag acagcttggt tgtcgaggct
    44401 gattggcatg gctatattgc aaccaagcca aaaggcgagc atggctttgg ctatgatccc
    44461 ttgtttatcg ttggggagac tggacgtcat gcagcagagc tagctgctga tgaaaaaaac
    44521 aagctgtctc ataggggaca ggcggtcaag aggttaatgg aggtatttcc agcatggcaa
    44581 gcaaaacaat cattgtgatg agcgattcgc atggcgatcg tgaggttgtg gcagctatta
    44641 aaggccgtta ccttggaaag gttgatgcca ttttccataa tggcgattct gagctagaaa
    44701 gctcagatcc tatttgggag gggattcatg ttgtggcagg caactgtgac catgatagcg
    44761 gctataagga tagcctagtc acctcctttg atggcttgac tattgctcaa acacatgggc
    44821 atttgtatca tattaacttt acttgggata ggctagatta ttttgctcag gagactggag
    44881 cggatatttg tttgtatggg cacttgcaca gacctgctgc ttggcaattg ggcaagactg
    44941 tctttatcaa tcctggctcg gtcgctcagc cgcgtggtga ggtgaatgaa aagctgtacg
    45001 cgcgtgttga atggacagca gcttgcatta gggtggatta ctttacctgt cagcataagt
    45061 cttacccatc actttctaag gaatttaaac gatgatagca aaagaatttg aagccttttt
    45121 aatcagtcat ttggatagct acctgattcc agcagaggag ctagccattt ttatcaacac
    45181 gcataatgct gatcatgtca tgctcttatt ggttagcaat ggtttttcac gagttcctgt
    45241 cattaccaag gaaaagcaat atgtcggaac gatcagcatt tctgatataa tgacctatca
    45301 agccaaaagg cagctaacag actgggagat gacgcaaact aatattggcg acatggtcaa
    45361 tacaaagatt gagaccatca atattacctc tagcttgact gaaatcatgc ataaattggt
    45421 tgattttccc tttttaccag ttgttaatga tgacaatcga tttatcggta ttattacgcg
    45481 taagtccatt ttgaaggcgg ttaatagcct tttgcatgac ttcactgatg aatacacaat
    45541 cacaaaaaaa tgatagcatt tattgaaccc tttctagcaa gcaaatctct tgctaataac
    45601 agccagcaat cctatcgcta tgatttaagg cagttttgcc agcaggtcgg acagcgtatt
    45661 aatcctgaaa ccctagccct ctatcagcaa agcttgtctg gccttacggt agcagctaaa
    45721 aagcgcaagc tttcaacggt caatcagttt ttgtactatt tgtaccagca gaaggctttg
    45781 acagactatt ttaaaatgga cgataggata gaagcctctt tttctttgaa gccccagctg
    45841 acaaggcttg acaccagcgc tttttatgct gaaacagcct tcctaaaagg gcagctcatt
    45901 gcgctgctga ttctggagct gggcttgacg ccaagtgaga tagcagggct tcgtcttgct
    45961 gattttgacc tgggtcttca ggtgctaagg ttgcaatctc acagaggcat tcgtgtgatg
    46021 accttatcaa aggccttgct gccatttttg gaaaaggcaa cagaagctca gcagctctac
    46081 ctctttgatc atgacgccaa gcccttttca aggcaatggt tttttaacca gctcagagat
    46141 tttttagaga gcattggctg tgcggagctt tcagcccaga gtctgagaga gcaattcatt
    46201 ttaaatgaaa aagcagccgg taaatccatc attgaggtgg ctcagctgct ggggctaaaa
    46261 agcccgatca ccttagaaaa atattataag atgtaatgga tataaaagta aaagattttg
    46321 aaggtcctct tgatttactc ttgcacctag tgtcaaagta tgaggttgat gtttaccagg
    46381 tgcctattgt ggaggtcatt gaacaatact tggcctatat tgagaccctg caggcgatgc
    46441 gcttggagct tgctggagag tacatgctga tggctagtca gctgatgctc atcaaaagca
    46501 gacgactgct gccaaagctg gtagacaagg agcctgatga ggaggatctt gagcaagagc
    46561 ttttgggtaa gattgaagaa tatagtcgtt tcaaggctct gagtcaggag ttggccagcc
    46621 agcatgacaa gagggctctg cttttttcca agccaaagca ggagcttatc tttgagcagg
    46681 ccgtcctaca aaaggataaa acagtcatgg atttgttttt agctttttca cagttaatgg
    46741 ctgcaaagca agaggccttt aaatataacc atacggttat tgagcgagat gattatcgta
    46801 ttgaggatat gatggagctt attgaagcta ggcttgagct agagcaggag cttactttga
    46861 cggatttatt gaagcattgt gatcatctca atgaggccat taccttgttt ttagcaagcc
    46921 tagaattaat caaacggcag cttgttggta ttgagcagac atcacatttt ggccagattg
    46981 ttttgcgaaa ggagatccaa tgacctattt atctcagctg gaggccttgc tgtttgtcgc
    47041 aggagaagaa ggactaagcc tacgtcagtt ggccagccta ttagagttaa caccgacagc
    47101 cttacagcag cagctcgaca agctttctca gaaatacaaa gaggataagg aatctggcct
    47161 gtgcttgatt gagtcctcta ggacctataa gttagtcacc aaagagtgtc tggctccctt
    47221 gcttaaagac tatgctaagg ctccaatcaa ccaaaccttg tcacgagcaa gcctggaggt
    47281 tttgtcaatt gttgcctata agcagccgat tactcggatt gaaattgacg agattcgtgg
    47341 tgtcaattca agtggtgccc ttagtaaatt agtggccttt ggtttggttc aagaggctgg
    47401 caaaaaggaa gtgattggtc gaccaaatct ttatgcaaca acagattact ttcttgatta
    47461 tatgggtatc aatcatttag aagagctggt tgatatttct tctattgctg ttgaagagca
    47521 agagacaacc ctgttttaaa ggcaaagagg agcttgtctc atttgcagat aggccttatg
    47581 ccctctacta gaagagataa cagtcctaac aaggtatagt gcctgaaaat cctattgtcg
    47641 ttatggacag cggtcttttt aggcatgcta ttaataagag tagacctgtt taagctagtg
    47701 agcttttacc cataggagag tgactggtct gttggagcta tcatcagatt tcctaataag
    47761 aaagagagaa ggataatgag aattaacaaa tacatcgccc atgcaggcct tgctagccgt
    47821 cgtaaggctg aagagctgat caagcgaggg ctggtgaccc taaatggtca ggtgataaca
    47881 gatttagcaa ctactgttaa atcaggcgac cttgttgagg tagaggggat tcctatttac
    47941 aatgaagaga aggtttatta tctcctcaac aagcctcgtg gtgtcatctc aagcgtttca
    48001 gatgataagg ggcgtcagac agtgattgat ttgctgccgc aggttaagga gcgcatttac
    48061 cctgttggtc gcttggactg ggatacctct ggcttattaa ttttgaccaa tgatggtgat
    48121 tttacagata aaatgattca cccccgtaat gaaatcgaca aggtttatct ggctcgtgtc
    48181 aagggagtgg taactaaaga aagcctgcgt cccttaacac gtggtgtcgt tattgatggt
    48241 aaaaaaacaa agccggctcg ttaccgcatt attcgtgttg agcctgataa aaatcgctct
    48301 attgttgaac taaccattca tgagggccgt catcatcagg tcaagaaaat gtttgaagtg
    48361 gttggacact tggttgataa gctatcaagg acacagtttg gcagccttga tgtcagaggc
    48421 ctaaagcccg gagaagccag aaggctgagc aaaaaagaag tcagccagct acatcattta
    48481 gcgagcacac gaaaatgatc aaagccctac tcattgctcc tgtcagagcc tatcagaaat
    48541 atatttctcc cttatttcct ccttcctgtc gttatcagcc gacctgctcg gcctatatga
    48601 ttacagctat tgaaaagcat ggtgctaagg gtgttttgat gggacttacc agactattaa
    48661 ggtgccaccc ttttgccgct ggcggagaag acccggttcc agataccttt tccttaaaaa
    48721 gacatttcat aacgcatgaa aaaatacagg attttgacca aaaaactgat tgacaatagc
    48781 agttaaagtg ctataatagc agttaagtat tcgttggttt aaatcaaacc tgttatgatt
    48841 taagttagcg agtcaccgtc aaccacattg tttgctgagc atgactccgg gcagtgtggt
    48901 ttttttgatg aaaagagtaa gcgggacaag catgaaacaa gaaatcatta atagacaata
    48961 tagggaaaaa gatagtcaaa accatgtggt gctctttcag ccacaaattc cacaaaacac
    49021 aggaaatatt gctaggacct gtgctgccac caacacgcct ttacatatca tcaggcctat
    49081 gggctttccg attgatgacc gtaagatgaa aagagcgggg ctagattatt gggataagct
    49141 agacattaga ttttatgatc atctagatga atttttagca caatgtgatg ggagcttgca
    49201 tgtgattagc aaatttgctg atagggtata ctcagatgaa gcctacaatg atcgtcagtc
    49261 tcattatttt ttgtttgggc gtgaggatac tggtctgcct gagcccttta tgcgtcaata
    49321 tgctgatagg gcactcagga ttcctatgaa tgatgagcat gtcagaagtc tcaatgtctc
    49381 taatgctgtt tgcatgatcg tctatgaggc acttagacag caagccttta agggcttaga
    49441 gcttagccat acctatgagc atgacaaact aaaatcataa taagcatatc gcaaaacatc
    49501 agttagattg aagaagtatc cgtaggggag cttcttcagt ctttttttat tgtattcttt
    49561 gcttattaac caagcagttg acacgaaaat tccaatagat cgtttaaagc caataaaa
//
LOCUS       DARYXW010000005        43316 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.005, whole genome shotgun sequence.
ACCESSION   DARYXW010000005 DARYXW010000000
VERSION     DARYXW010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43316
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.005"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(335..694)
                     /gene="rplT"
                     /locus_tag="TV191_000220"
     CDS             complement(335..694)
                     /gene="rplT"
                     /locus_tag="TV191_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEL1506772.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AAAFTALADAAKAKLGK"
     gene            complement(755..952)
                     /gene="rpmI"
                     /locus_tag="TV191_000221"
     CDS             complement(755..952)
                     /gene="rpmI"
                     /locus_tag="TV191_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEL1506773.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAFTSHRFHGKTKKQRRHL
                     RKAGMVHAGDFKRIKAMVTGL"
     gene            complement(992..1522)
                     /gene="infC"
                     /locus_tag="TV191_000222"
     CDS             complement(992..1522)
                     /gene="infC"
                     /locus_tag="TV191_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEL1506774.1"
                     /translation="MKIIAKKDLFINDEIRVREVRLVGLEGEQLGIKPLSEAQSLADA
                     ANVDLVLIQPQAVPPVAKLMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPVIDKGD
                     FETKLRNGRKFLEKGNKVKVSIRFKGRMITHKEIGAKVLADFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPISDKK"
     misc_feature    complement(1537..1659)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            complement(1683..2363)
                     /locus_tag="TV191_000223"
     CDS             complement(1683..2363)
                     /locus_tag="TV191_000223"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEL1506775.1"
                     /translation="MKAIRIAIDGPASSGKSTVAKIIAKNLGYTYLDTGAMYRSATYI
                     ALKNGYHKEDVNLILQELAKRPISFKKAADGSQLVFLGDQDVTMAIRQNDVTNNVSWV
                     SALPEIREELVNQQRRIARTGAIIMDGRDIGTVVLPDAELKIFLIASVEERAQRRYQE
                     NIEKGIAADFDTLKAEIAARDYKDSHRQVSPLKAADDAIIFDTTGITISAVVQFIQEK
                     AEKIIDMA"
     gene            complement(2378..2875)
                     /locus_tag="TV191_000224"
     CDS             complement(2378..2875)
                     /locus_tag="TV191_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEL1506776.1"
                     /translation="MAKEPWEEKIVDDNKATRTRKSRGALISTPWLTALLSVFFVIIV
                     AILFIFFYTSNSGSNKQNETTGFYGASTQKKTTKKVSSKPKTKPKASSNSSAASDTTS
                     PSKTETAPSTEAAGKTITVLAGEGATSIAARAGISVEQLQALNPDHMTQGYWYANPGD
                     EVNIK"
     gene            2924..3121
                     /locus_tag="TV191_000225"
     CDS             2924..3121
                     /locus_tag="TV191_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEL1506777.1"
                     /translation="MKVSILPEKCIACGLCQTYSALFDYHDDGIVKLAQSDESSQLID
                     PNDHDAILAVKSCPTKALTLE"
     gene            complement(3108..3596)
                     /locus_tag="TV191_000226"
     CDS             complement(3108..3596)
                     /locus_tag="TV191_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HEL1506778.1"
                     /translation="MIKLFGKVRYHWQPELSWSIIYWSIAVAPIFIGLSLLYERTEIP
                     SRVFVLFALFAILVGLGLHRYFVIENNGVLKIVSLKLFAPHRLMIASITKIEVTKSTV
                     CLFVGDKSYLFYMRKWPKKYFLDDLAINPYFKGEVILLDNFIKLDYFEAYQYEKKPLT
                     RG"
     gene            complement(3641..4864)
                     /gene="pepT"
                     /locus_tag="TV191_000227"
     CDS             complement(3641..4864)
                     /gene="pepT"
                     /locus_tag="TV191_000227"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEL1506779.1"
                     /translation="MTYETLLERFLNYVKINTRSNPASTTTPSTKSQADFALTVLKPE
                     MEAIGLQDIHYNPANGYLIGSLPANSSKLTRKIGFIAHMDTADFNAEGVAPQIIESYQ
                     GGEIKLGQSGYSLCPEDFPNLNQYLGQTLITTDGTTLLGADDKSGIAEIMTAIEFLVA
                     NPQIEHCDIKVAFGPDEEIGVGADKFDVNAFDVDFAYTIDGGPLGELQYETFSAAALE
                     LKVLGRNVHPGTAKNQMINALQLAMDFHSQLPVDDRPEKTDGYQGFYHLHSMSGTVEE
                     AQASYIIRDFEDSSFEARKAFVTQLAEEMNSQLGAERVFVTVTDQYYNMKKVIEKDMT
                     PVNLAKAVMEDLAIKPVIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEFVSLQT
                     MEKAVDVILGIVQKA"
     gene            complement(5034..6053)
                     /gene="galE"
                     /locus_tag="TV191_000228"
     CDS             complement(5034..6053)
                     /gene="galE"
                     /locus_tag="TV191_000228"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEL1506780.1"
                     /translation="MLGSILVTGGAGYIGSHTCVELLAAGYDVVVVDNLCNSNPKSLA
                     AVASIAGREVTFYQGDIRDQQLLTDIFSKHPIVSVIHFAGLKAVGESSRIPLDYYDNN
                     ISGTLTLLKVMTAFNCKKIIFSSSATVYGDPHTVPILETFPLSVTNPYGRTKLMLEEI
                     FKDLYASDNEWHIVLLRYFNPIGAHESGDLGEDPKGIPNNLLPYVSQVAVGKLDCVGV
                     FGDDYETKDGTGVRDYIHVVDLAKGHVAALAKFAEEPSLSIYNLGTGTGYSVLDIIEA
                     FSQVVGRSIPYKILPRRQGDIAACYADASKAKKELNWTAEYGLERMCTDTWRWQSKHP
                     NGYED"
     gene            complement(6121..8490)
                     /locus_tag="TV191_000229"
     CDS             complement(6121..8490)
                     /locus_tag="TV191_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEL1506781.1"
                     /translation="MLDMILFSLSSLYLSIFAVSKNTLNKGAYGSWLVLVLIAGMACL
                     LIKHASSKLLIVSVAVSSYYAVANSYITLAINKNNSRFTISNRTIQEMLLSLAALVSL
                     LILGVLLKKYLFKKDYQSNRGIQVILLSQAFSVLTLNSSLFKTVIKQNDYWPLDSQSN
                     LVSLNLFKYSFCSYMLTFVVYYLIVTAFIEVLSKRWGLRLALVTSLFLGIIFNYFIQA
                     GITAYGDFHGAVIIPGATLFQVLVLTLFFVLVFLLINNYIIALFVNTVIGALISIVNI
                     EKYKQRSEPLLFSDLKWIKEIKFFLNYISLTQIISIILILVLSGLLIYVLYKRYFREK
                     ILSALYLRLMSIGSILLVFASILFVFSQNKDGEIKKGIPVLSSVYNVFDIDWYGLTTN
                     ARFQSLSFVWFKQVTTSTINQPSGYSKSAMQKIYQKYQARAADINKQRHQRISDQTVI
                     YILSESFADPARISGVQLAKDPIAEIHHIMETTTSGLMTSDGYGGGTANMEFQSLFGL
                     PKYNLNPTVSILYSDVFPKLKFSPAISNAFSPKDRIVLHLASANNYSRKIVYNKLGFD
                     TFIATEDSADKPKHLIRMSSSYSDESTYDNILDQLNPKRSQFFSVITMQNHGPWYTEL
                     RDVDVSLAGLDQSETDSLQSYVNLLSITDKSTKAFLSALEKVDKPITVVFYGDHLPGF
                     YPDQVFKNDEEVKYLTDYFIWSNHQTNKLARPRVNSSDFTSLLLEHTDSKVSPYYALL
                     TDVLDTRNSDDSQLTAAQKQVASDLKLLEYDLIEGKGYINAYPDFFKMK"
     gene            complement(8570..9733)
                     /locus_tag="TV191_000230"
     CDS             complement(8570..9733)
                     /locus_tag="TV191_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEL1506782.1"
                     /translation="MKTIAIFSGFTSPHLGGVERYTEKIAQQLVSLGYRIIIVTSNSH
                     QLSPIERDQAITYYRFPSKQLFKQRYPILDKNDLYHSMLAELMEERIDFVICNTRFYL
                     TSLMGLKLAKRKAIPSIVIEHGGGYVQVGENVKGHQLLDLFAKVYEHVITFFVKAYQP
                     DFYAVSKRSMAWLKTFGIKAKGVIYNSVDSDLYEVFKSKAYLPALQDKVIITFAGRVI
                     KEKGILLLLEAFEQLTYKDRAVLVVAGDGPLLASLRDSYKEDQSIIFTGKLNFAETMS
                     LLSQSDIFVNPSIYAEGLPTAVLEAGMLKCAVLATDRGGVKEVITSPSQGIIIDDTVS
                     DIKRQLDHLIEHKEKRCDLQEAIHQQVLSGFTWEVTVRQLVTEVIASESESNV"
     gene            complement(9747..11231)
                     /locus_tag="TV191_000231"
     CDS             complement(9747..11231)
                     /locus_tag="TV191_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2142 domain-containing protein"
                     /protein_id="HEL1506783.1"
                     /translation="MLDTLFDKLQKASKALLVLLGAFLVLLLLYTQSTDLPIKFLAIL
                     VAIAALLIIFLPSNMEYATVLIIVVMGSVSAFISPINDIPDERVHFARALYLSEGNLN
                     LTNDDSKLLVTDDINLMDHNNGKPLRFQLWSRDHTDEAISFKEIRSTNGYYNFAYIPQ
                     VIGLFIGRSLGLTMGLSYLLGRLCNVLAYAILVFVALRLLTAGKQLLAVGSLLPMNIY
                     LAGSYNQDCVSIGLIILTISLFVQMATTEKIPLSKLFWYTLLCSIITFTKLPYILLIL
                     LLLFIPSRQFGAKASRTFLLKLLSILTVLVVTVFWLKVYGQIKSPQVDMADFLQKVNA
                     KEQLLTVLRNPIVYGFMLLRHTLAHILNPSGIYMFGPLSYGMVELMPISMVYYFAVVI
                     TNANKLQLPTLSRFGMGLMSLGIIGGITFSLYLTFTPVGDLNVLGVQDRYFLGVIPLV
                     LVLLASNNKYLEKAQGLLSNKQVLIGSLLLILGMITRTMLQYYT"
     gene            complement(11235..12476)
                     /locus_tag="TV191_000232"
     CDS             complement(11235..12476)
                     /locus_tag="TV191_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HEL1506784.1"
                     /translation="MKTSSRIQSDQSIFIWNVLGTSSTALISVILLMIVSRVLSKSAS
                     DTFSFAYAIGNQLITIGLFQIRNFQSTDILHKYRFKDYFYTRLVTCFLMIAISVLYIY
                     LGSYSGFKGLVIWLICLYRCTDAISDVFQGMFQQRERLDIAGKSLFYRNMLVILGFTL
                     CLVLTKQLVLSLIVICLISVACIVLFDITPSVSFTSLERRIDAQSILGLLKESFPLFL
                     NGFLLIYIYNQPKFVLEQLYSKQLIPAGVQTEFNILFMPIFMINLIFLFLRPMITQLA
                     IYHSKEDKKSFAQLERRLSLVLLLASLAILLASYFVGLPVLSLVYGIDLRHYQLDFML
                     LIFGGIISTFATYIDNLITIIRKQHLLVIPYVVSFISSLAITGSLARSFGVIGVTYGF
                     IISMMIWLLLSYGLYIMEKRK"
     gene            complement(12460..12816)
                     /locus_tag="TV191_000233"
     CDS             complement(12460..12816)
                     /locus_tag="TV191_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2304 domain-containing protein"
                     /protein_id="HEL1506785.1"
                     /translation="MFIGLQLILIIVALLTAMFILDSIRRSKILIEDSFFWLFFSLIV
                     LLLSLFPNAAVYFSRLLGFESPANFVFLSIIFLLIINQFFITQKLSRTEIKLKKMIQY
                     LALNEKEKQEEDENQQ"
     gene            complement(12821..13510)
                     /locus_tag="TV191_000234"
     CDS             complement(12821..13510)
                     /locus_tag="TV191_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL1506786.1"
                     /translation="MKKDLLVMIPAYNEEESIEKVVENIKRHFPQYDYVIINDGSSDR
                     TSEICHHNHYNIIDLPENLGLSGAIQTGFKYAFKKGYAKALQFDADGQHLPEYIEALS
                     DSINAGADCVIGSRFVSAEKNRSLRMIGNSLISFFIKLTTGKRITDPTSGMRMFNQEL
                     IRIFATNINYTPEPDTISYLIRQGYRVSEVQVQMNDRLAGQSYLTLSRSIKYMVHMFI
                     SIILIQNFRKR"
     gene            complement(13540..15285)
                     /locus_tag="TV191_000235"
     CDS             complement(13540..15285)
                     /locus_tag="TV191_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-Rha alpha-1,3-L-rhamnosyltransferase"
                     /protein_id="HEL1506787.1"
                     /translation="MKRLLLYVHFNKYHKVSDHVYYQLEQMRALFSKIVFISNSDIHQ
                     EDLEQLEQRHLMDQFIQRHNKGYDFAAWHDGMKALGCEHLVDFDSITIMNDTCFGPLW
                     DMKPYYLKYEADEAVDFWGMTNNRATKAFKEHIQSYFISFKKSLVHSKEFRQFWENIV
                     ELTDVQDVIHNYETRITTVFVEAGFRYKTVFDTTKEDSSSMLHADFSYYNPTAILKHH
                     VPFIKVKAIDANQHIAPYLLDFIDQKTTYPASLIVDHMSQVHPPDAKYLLAHKYLPEQ
                     PISIDQSKKIAVHLHVFYVDLLSEFLEAFSHFHFDYDLLITTDSKAKKAEIKEILRES
                     GASADILVTGNIGRDVLPMLTLKERLSQYDYIGHFHTKKSKEADFWAGQSWRTELIDM
                     MVKPADQILTALAADAIGIVIADIPSFFRFNKIVDAWNEHLIAPEMNQLWQAMGLTKR
                     IDFQTMDTFVMSYGTFVWFKYDALKPLFDLDLSEADIPAEPLSQNSILHAIERLLIYI
                     AWDRHYDFRISRNEKLLTPFIDNKLLNLREGSVPHTYVDFDYMGGIKGALKYIVIGPA
                     KAIRYIIKRLLKRRV"
     gene            complement(15282..16289)
                     /locus_tag="TV191_000236"
     CDS             complement(15282..16289)
                     /locus_tag="TV191_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEL1506788.1"
                     /translation="MKKVSIICTNYNKGPWISEALDSFLAQQTSFDVEIIVIDDASTD
                     YSRQILMDYQASFPDRIRLIVNEVNLGIARTWVKACLEAKGQYIARCDGDDYWTDTLK
                     LQKQVDLLDSSPDSKWSNTDFDFVDTDGKLIQSNAFESGFTPLTDTYEKMLALKGMTM
                     SSTWLVEADLMRAVNQRIDLETSDDTFDIQLELFQSTSLAYLKDSTTVYRMTDNSDSR
                     PAAEEKMLGRIQGLLETQLSYLSKYPTANMEAIAKALLKQDAKNEIRIHQLSHTIHQL
                     RQTLADQEALQAEKIDQLQQQLDHQRQEVEALTHQYNCVVTSRRWRYLSKLLELFRRK
                     K"
     gene            complement(16310..17518)
                     /locus_tag="TV191_000237"
     CDS             complement(16310..17518)
                     /locus_tag="TV191_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1506789.1"
                     /translation="MANKEIAVTVDHVSKSFKLPTEATKSFRTALVNRFKGIKGYTEQ
                     HVLRDISFDVYKGDFFGIVGRNGSGKSTLLKIISQIYVPEKGQVTVEGKMVSFIELGV
                     GFNPELTGRENVYMNGAMLGFTTEEVDDMYDDIVDFAELHDFMNQKLKNYSSGMQVRL
                     AFSVAIKAQGDVLILDEVLAVGDEAFQRKCNDYFMERKESGKTTILVTHDMGAVKKYC
                     NRAVLIENGLVKAYGEPFDVANQYSVDNTELKNAEQGAAAEPVSDLASQLEVRLTSKP
                     SLSPDEPISFEISYHVLKDEPTYVAFSLTDIDRNIWVYNDNSQDQPTSGPGHKNISYQ
                     CQLSHLNDIKLKLEVTVRDQNGQMLLFLTANHSPLVVLQRNDIAPDDLSALDSASGLY
                     QRNGSWLINQ"
     gene            complement(17518..18321)
                     /locus_tag="TV191_000238"
     CDS             complement(17518..18321)
                     /locus_tag="TV191_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1506790.1"
                     /translation="MELLSKKNRILLKELVKTDFKLRYQGSAIGYLWSILKPLMMFTI
                     MYLVFIRFLRTGGDVPHFPVALLLANVIWSFFSEATSMGMVSIVSRGDLLRKLNFSKH
                     TIVFSAVLGALINFSINLLVVLVFAAINGVTLSPHAYLALPLFVELAVLTVGVALMLS
                     TVFVYYRDLAQVWEVLLQAGMYVTPIIYPITFVFDRHPLAAKILMLNPLAQIIQDLRY
                     LLIDRANVTIWQMSTNWCYIIIPYLIPFVLLALGVAVFNKNAKKFAEII"
     gene            complement(18321..19256)
                     /locus_tag="TV191_000239"
     CDS             complement(18321..19256)
                     /locus_tag="TV191_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL1506791.1"
                     /translation="MKINILMSTYNGARFLAEQIQSIQRQTVQDWTLLVRDDGSTDKT
                     LAIIQAFAKKDPRICLINADVQENLGVIRSFHTLLTYEKADIYFFSDQDDVWLDNKLE
                     LTLAEAQKHKISEPLLVYTDLKVVNQDLEVRHESMIQTQSHHANTQLVQELTENTVTG
                     GTMMINHALAEQWVSCEHVVMHDWYLALIAAAQGELVYLDVATELYRQHDANVLGART
                     WSKRLKQWRKPHKLIEKYWWLIVSSQHQARQLLDLQLNPADRRLIEAYVGLLDRPFYQ
                     RLSDFKAYGFRKNRAFHTLVFMALIMTKFGYRRKE"
     gene            complement(19246..20400)
                     /locus_tag="TV191_000240"
     CDS             complement(19246..20400)
                     /locus_tag="TV191_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1972 domain-containing protein"
                     /protein_id="HEL1506792.1"
                     /translation="MQDVFIIGSRGLPAKYGGFETFVEELVTNQTNKSITYHIACLSD
                     SKHKEHFVYKGADCFYINPPKLGPARVIAYDMMAISHALAYIDRYHIQKPIFYVLGNT
                     IGGFIAPFAKQIHQRGGRLLINPDGLEWKRSKWSKPVQQYLKYAEKQMTKHADLVISD
                     NIGIEAYIKKSYPWAKTTFIAYGTEIGRSCLSTSDEKVRTYFQTFEITENQYYLILGR
                     FVPENNYETAIREFMASSTQRDLVIICNHDKNPYFERLVSATGCDKDARVKFVGTQYD
                     KQLLAYIREHAFAYIHGHEVGGTNPGLLEALAHTQLNLVLGVTFNQSVAKTAALYWTK
                     EKGSLTGLINRVDQKESFADLGERAKQIIAKEYTWEKIVGEYEALFLDED"
     gene            complement(20525..21373)
                     /gene="rfbD"
                     /locus_tag="TV191_000241"
     CDS             complement(20525..21373)
                     /gene="rfbD"
                     /locus_tag="TV191_000241"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEL1506793.1"
                     /translation="MILITGSNGQLGTELRYLLDERSVDYVAVDVAEMDITNATKVEE
                     VFAQVKPSLVYHCAAYTAVDAAEEEGKALNEAINVAGTEHIAKACERYGATLVYISTD
                     YVFDGQKPAGQEWLETDTPDPQTAYGRAKRLGELAVERYTKQFYIIRTAWVFGHYGKN
                     FVFTMQNLAKTHSRLTVVNDQHGRPTWTRTLAEFMCHLADNRKPYGYYHLSNDAKEDT
                     TWYDFAREILKETAVEVVPVDSSAFPAKAKRPFNSTMNLDKAKATGFVIPTWQEALEA
                     FYKQQQ"
     gene            complement(21515..21853)
                     /locus_tag="TV191_000242"
     CDS             complement(21515..21853)
                     /locus_tag="TV191_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEL1506794.1"
                     /translation="MTETLKYTEEQVAAIKDRILEALGTVIDPELGIDIVNLGLVYEI
                     RFDDNGHTEIDMTLTTMGCPLADLLTDHIHDAMRDVPEVTKVEVKLVWYPVWSVEKMS
                     RYARIALGIR"
     gene            complement(22151..23260)
                     /gene="rpoD"
                     /locus_tag="TV191_000243"
     CDS             complement(22151..23260)
                     /gene="rpoD"
                     /locus_tag="TV191_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEL1506795.1"
                     /translation="MAKEKEITTFNVQIAEFIRHHKKEGTATDDEVTEKLVIPFTLDA
                     DQIDDLLERLTDGGISITDKEGNPSSKYVVEEPKPEELTDEELIGSNSAKVNDPVRMY
                     LKEIGVVPLLTSDEEKVLAVAVAAGDMEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMEMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRVVLREQLDEVLDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRHPSRSKQLRDFIED"
     gene            complement(23269..25083)
                     /gene="dnaG"
                     /locus_tag="TV191_000244"
     CDS             complement(23269..25083)
                     /gene="dnaG"
                     /locus_tag="TV191_000244"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEL1506796.1"
                     /translation="MGFLWGGDGLAIDKEMISQIKHNVNIVDVIGEVVHLSRAGRHYL
                     GLCPFHKEKTPSFNVIEDRQFFHCFGCGKSGDVFKFIEEYRQVPFLESVQIVADKAGM
                     AVTVAPSQTSLSQKQHPHQALIDLHEDAAKFYHAVLMTTKIGQRAKEYLYQRGLDDQL
                     IEYFRIGLAPNEMDYLYQALSKKYTEAQLTASGLFHVSEQSNAIYDAFRHRIMFPLCD
                     DKGNMIAFSGRIWAREDIEKQQAKYKNSRATVLFNKSYELYHLDKAKPIIAKTHEVFL
                     MEGFMDVIAAYRAGYGNTVASMGTALTPEHVRHLKQLTQKVVLTYDGDDAGQNAIAKS
                     LELLADFQVEIVKIPNRMDPDEFVQQHSPEALAELLQHSRISSVEFLIDHLKPENMDN
                     LQSQIAYVEHISQIIAQAPSITAQNSYINKVADLLPDFDYFQVEQSVNALRLQDRQSL
                     QQGQASQPKASLVTLPINKSMTALAKTESHLLHRLLHHDYLLNEFRHRPDFYFDTPAL
                     QTLYEQLKATGQITSYDLSQLSEEVNQAYYRVLEENLPDEIASGEIEDILSRQMTLLK
                     QRELHRQGKQIRESSSKGDHQMALEALERFIAEKRKME"
     gene            25330..25704
                     /gene="mscL"
                     /locus_tag="TV191_000245"
     CDS             25330..25704
                     /gene="mscL"
                     /locus_tag="TV191_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEL1506797.1"
                     /translation="MLKELKAFLFRGNIIDLAVAVIVGSAFSAIVTSFVNDIITPLIL
                     NPALKAANVENIAQLAWNGIKYGSFLSAIINFLIVGTSLFFVVKVAQKAMPKKGEEEP
                     AKPKTPTQEELLLDIRDLLAKK"
     gene            complement(25930..26106)
                     /locus_tag="TV191_000246"
     CDS             complement(25930..26106)
                     /locus_tag="TV191_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEL1506798.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVTKAGTLQESRKREFYEKPSVK
                     RKRKSEAARKRKKF"
     gene            complement(26261..27073)
                     /locus_tag="TV191_000247"
     CDS             complement(26261..27073)
                     /locus_tag="TV191_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEL1506799.1"
                     /translation="MNMKRLLVGALAMVSVFALAACGQANKTSLQDRIQEKGKLVVAV
                     SPDYAPFEFKALVDGKDTIVGADIELAQAIADELGVKLELSAMNFDNVLSSLQTGKVD
                     IAISGLSYTKERAKVYDFSEAYYETENAILVKASDAKHYANKDSLVGKKVAVQKGSIE
                     EGLVKEQLNKANCVSLTVMGEAINELKSGQVQAVDLEAPVAAGFLAQHKDLALAPFKL
                     QASDGDAKAVAMPKGSDDLRQTINKVIKQLNKDGKYKAFIQEAALLTGNAVE"
     gene            complement(27141..28256)
                     /locus_tag="TV191_000248"
     CDS             complement(27141..28256)
                     /locus_tag="TV191_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HEL1506800.1"
                     /translation="MKLPVFGVEEWLNQHEKRAVYDIAGSSIASLTLEELFDLTQEQP
                     QAFYQQLHQKPLDYGWIEGSPDFKQAVAGLYQQQKARNILQTNGATGANFLVIYALLE
                     AGDHVIAHYPSYQQLYDIPASLGVEVDYWQIREEQAWLPDLNELGAMIRPNTKMIMIN
                     NANNPTGAYMTKPYLEELINIAREHDIYLLSDEVYHSFTSDHLLAVADLYDKGITVNS
                     MSKTFSIPGIRVGWVAASETICDQLRLYRDYTMICAGVFDDMVASLALKHADKLLQRN
                     QAIIRTNLAILEDWITGEARASYHRPNEVSTAFVRLDIDEDMEAFALRLLEDYGTLVV
                     PGNRFNQANHVRIGYCCQPQVLQAGLSRLSQCLKNIQ"
     gene            complement(28526..32167)
                     /gene="addA"
                     /locus_tag="TV191_000249"
     CDS             complement(28526..32167)
                     /gene="addA"
                     /locus_tag="TV191_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEL1506801.1"
                     /translation="MRIDEGFLTPEAIARLQQEEALSDKTHKRTAQQIEAIYSSGQNI
                     LVSASAGSGKTFVMVERILDKILRGIPVDCLFISTFTVKAATELIERIEKKLHTAIAE
                     TQDYQLKAYLNDQLQALSQADIGTMDAFAQKLVHQHGYVLGISPHFRIIQDKAEQDIL
                     KREVFRQVFEDYMSQTDNKAFIQLVQNFSGRRKDSSAFREIVDSIYAFSQSTANPSSW
                     LAEVFLRGSKTYTSFTDIPDQAVDALLACMQDTADQLRDLTDMEGYAQTTKAGKLTAK
                     YTKHLKMIDSLYEWALHFDSLYGKARLGQLAQELTALLPSGADITVAGHKYPIFKSLQ
                     EQLVRFRHLETILAYQQESLPLLEVLQAFVISFSEAYLAAKMQENAFEFSDIAHFAIE
                     ILQQAPDIRQAYQGHYHEVMVDEYQDNNHMQERLLELLSNGHNRFMVGDIKQSIYRFR
                     QADPQIFNQKFKDYQSNPEHGKLILLKENFRSQSEVLNVTNAVFSRLMDESLGEITYD
                     DKHQLVAGSEGQRQPYPNNRAQLLLYDTDQVQEGTEEALANDGISAGEVILVAKEIIR
                     LYNEEKVAFEDITLLVSSRTRNDTIFQVFNQYGIPLVADGGQENYLKSVEVMVMLDTL
                     RSINNPLNDYALVALMRSPMFSFDEDQLARISLQGSSQKQPQAFYDKLSNSLRGQGEH
                     PELIGQELMTKLADFDGTLRDWRQFAKLHSLYELIWKIFNDRFYFDFVASQPKAEQAQ
                     ANLYALAIRADQFEQSGYKGLSRFIGMIDKVLETQNDLADVEVERPKHAVNLMTIHKS
                     KGLEFHYVFILNCDKRFAMADLQAPIILNRDEGIGIKYVANVKELLREEKLASLKVTM
                     ETLPYQLNKQQLRLATLSEQMRLLYVAMTRAEKKVYLIGKASKEKVQEKTADNSSEGR
                     LALASRERLLSFQDWLLAIAATFSKEDLFIDVRFVDDSDLTPEAVGQLRPSGLLQADD
                     LKDNRQTEDIARALDMLDKVSELNASYQAAIELPTVRTPSQLKTLYEPLMDTDGVDII
                     DQPYHRPKTFELPDFSKKKAVEPSQVGSSLHELMQRIPMSDQVTAGDIEQTLQLVSAD
                     AEVKARLDIEKVTSFFATTELGQLLQEHHQRLHREAPFAMLKKDSLSQEQYVVRGIID
                     GYLLFEDRIVLFDYKTDRYQQSAELKQRYQQQMDLYAEALSQSYGIARIEKYLVLMGG
                     SQLEVVRLA"
     gene            complement(32157..35378)
                     /gene="rexB"
                     /locus_tag="TV191_000250"
     CDS             complement(32157..35378)
                     /gene="rexB"
                     /locus_tag="TV191_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEL1506802.1"
                     /translation="MKLLYTEISYSMTEILVKEARAYADKGYRVFYIAPNSLSFEKER
                     SVLALLPEQGSFAITVTRFEQMARYFTLAKAANRQALDDNGLAMIFYRVLMQLQEDEL
                     KVFHRLRTDQAFIAQLVELYKELQAANLTAFDLTTLDRPEKQEDLITIMTKAEQLIAQ
                     GDYDQSSRLAQLAEAIKSKSLDDELRQTVLVIDGFTRFSAEEEQLLALLNEACEEIVI
                     GAYISQKAYRLAFTKGNLYEASLAFIQQLAQQFQTKPIYTTSEKVFDVSFSRLTQLLE
                     ANHDYSKLDWQLSAKDKSKVVIWQALNQKEELEHVAKAIREKLYQGYRYKDMLVLLGD
                     VASYQLQIGPIFEKFEIPYYIGKQEPMSAHPLVQFVESLERGRRYNWRREDIVNLLKS
                     GLFGRFQEGELDQLEQYLVFADIQGFTKFSRPFTLNSSRQYPLPLLNQLRLAVVTPLQ
                     QLFKSQKQLGASLLDKLMTFFKTIQLADNFEALAGSRRETDREKDEEVWKAFTGILET
                     FYQVFGQEKMTLADCLALIKMGMQTAHYRTVPATLDVVSIKSYDLVEPHSKPFVFAIG
                     LSRSHFPKQTKNTSLISDQERASINEQTASYQRLDVPSFENIKKNHQTALSLFNAATQ
                     ELVLSLPTSLTNSSDDVSPYLKELIALGVPVIEKGKNRLSHSAADIGNYKALLSRLVA
                     INRQGIADDMTSEDRNFWTVALRYLKRRLADEQLSLPAFEHHLTTKPVAPEVIETRFS
                     SQQPLNLSSSALTVFYNNQYKYFLKYVLGLQEPESIHPDARIHGQYLHRIFELVTKDR
                     SNAAFDQKLGAAIAAVNQQSAFQQVYQADAEGRYSLEVLKGIAYSTASVLDLNQGLQI
                     TKQEEAFELALGQQVLIRGVIDRIDQLADGRLGIVDYKSSARVFDIVAFYNGLSPQLV
                     TYLAALKNKGQGLFGAMYLHMQEPRLSLSDFKALDDQLVAAAYKELTYKGIFLAQAKE
                     YLANGSYHLNNTLYETDELETLLAYNEQLYLSAVKQIKTGHFLINPYTADGKSVQGDQ
                     LKAITRFEADLDLGYARRLVVLPTKERRQAFLTRMNEEIKHED"
     gene            complement(35587..36987)
                     /locus_tag="TV191_000251"
     CDS             complement(35587..36987)
                     /locus_tag="TV191_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL1506803.1"
                     /translation="MIVQLLFLVLKYSQYLFLAFLIAYASFLLLSLIVGTIHLYERRQ
                     QAPVGGDVSLPPVSILVPAYNEELTIIETVESLLMLDYDCYEIIVIDDGSTDHTAKLL
                     KEQFHLEAVTCSINQRIPTRPLKAVSQKQLKHIKLTLLEKANGGKGDSLNLGINAAQY
                     DYLLCMDADSMLQEDSLKRIAKTAAKDPSVIAVGGMVKVSQGVALAAGRIVDYHLPRQ
                     LISCAQAIEYDCAFFGARVLLDQAAGNLIISGAFGLFKKELAIAVDGYDTGTLGEDME
                     LVMKLHFFCHNNKIPYRIGYETDAICWSQAPSRLKDLCRQRRRWFLGLYQCLKKYLQF
                     FVSCRFKATVLISYVLYLLFELLSPFIEAFGVIIIVLSLLCHQLNTTFFVSLMLLYIC
                     YCVLIALTSFLNRVYLQNNSSITLFDMAWVIYAAIYQCLVLHTVLTLIKVSSFIGYQR
                     KKNAWGQITRDKHRAA"
     gene            complement(37129..39270)
                     /locus_tag="TV191_000252"
     CDS             complement(37129..39270)
                     /locus_tag="TV191_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1506804.1"
                     /translation="MKKYLIFVGLLLSVIGLSYYCCDIDGRLYLPVSNQSAIRTVFYT
                     KDKRIYDQKGSPYLIKGVDVESSIAGYRRRDLSVDEKTYYRWFKQIAAMGANTIRVRV
                     IMPVTFYHALRRYNDRASHPLYLLQGFRIDAYHDNSSISALDKAYLGTLLREARASVD
                     VIHGRKRIWHSDLGLQHYDQDMSKWLLGYIVGDDWYSGTIAYTNHQNHAKPVGFKGRY
                     YATTPQANRFEAILAEIMEEITSYESRKYGWQHLVSFSNTPQSDPFVYQDPFASQAAK
                     YVQLTIENIKPSAKVKAGLFASYKLLDCHSAYRDYLLFDRLGLTDRLVGDIKRMPLYQ
                     GYVKLLTSYHRVPVVVTGYGYSTARGVDQMISTSSPLTEKDQGERLMADYTAFIASGC
                     CGATIHSWQDDWTARSWNTSFATNKHQSFLWGDVQSKAQGYGLLTFEHAPRTHAIDGQ
                     KAADEWSRALTYKKNGQQLLVDQDEKYLYIAIESTKKQPLQRQWLIPLDITPKTGSRV
                     IEGFSARFDRFADFALVVDDHKGSRLLVQERYHATDANYLRQINGKDFYVFPPNKHTP
                     RFTMVDMVVRNDGIFAAIDQVPIAKRGLKRYPTGQLKQGNGKRGSAHFDSQTDISFGE
                     RLIELRIPWQLLNFSDPASNKIHDDYFEHYGVEELAIEAIAIGFAPLKESKVIAMVEY
                     PLLSWERPRVREVLKTSYQQVQAVWQEKRRR"
     gene            complement(39277..40710)
                     /locus_tag="TV191_000253"
     CDS             complement(39277..40710)
                     /locus_tag="TV191_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CotH kinase family protein"
                     /protein_id="HEL1506805.1"
                     /translation="MKEKTIYVIVLVCLLLAAICGIGFPKTSAKRIHHHLQTVKKSSR
                     STGEFSSHLPIISIDTHHQQIPEQREYEGETKRQKTIKTTVSLRDQLDREHSLSESPR
                     LSLTALIAYRGNSSRHFDKKSLKLRFINKRAKPKAVSLAGMSKESEWVLHGPFLDRTL
                     VRNYLSYNIAGEIMTYAPNVRYCELVVDHQYCGLYLAVESIEQGRHRVNIEKSDRKSD
                     KTPYILVWDRRHKAKQALDHYVSYTNQAGLSSLDIKYPSLHRLTPKQKQFIEKDISHI
                     EKLLYSYDLKQYTDYLDQESFADYFIINEFFRNIDAGKFSTYLYKDLRDKLKLVVWDF
                     NNAFDNQIEAPYDEADFTLSDAPWFCMLLKDPSFVKLVVTRYHQLRQNVLSTDYLIKY
                     IDATVAFLGPAIQRNYHKWGYVFTVPSRSDATNYLVPASRNYSSYEASVKQLKDFIRR
                     RGRWLDKHIETLYQYSAPSKNTNTLLE"
     gene            complement(40716..41393)
                     /locus_tag="TV191_000254"
     CDS             complement(40716..41393)
                     /locus_tag="TV191_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4956 domain-containing protein"
                     /protein_id="HEL1506806.1"
                     /translation="MKQLLRHVFEQRGTLSFQDVLLHIVAAALLSIVIYMSYAYTHTG
                     TAYSKKFNVSLMTLTVLTATVMTVIGNNVALSLGMVGALSVVRFRTAIKDSRDTVYIF
                     WTIVVGICCGVGDYTVAATGSSVIFMLLLLMGAVRNDNRLLLIVRCDKQMEIELERLV
                     FNYFSGKAIQSVKNTTSDDIEMIFELSRKDYDSTYQQANPLTEAVYQLGRVDYFNIVS
                     QSDDITG"
     gene            complement(41407..42102)
                     /locus_tag="TV191_000255"
     CDS             complement(41407..42102)
                     /locus_tag="TV191_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001006716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate polymerase domain-containing
                     protein"
                     /protein_id="HEL1506807.1"
                     /translation="MNEVLRQEKKYLITIEDYYRLSHEFSKLLRLDAHSSSEGYVIRS
                     LYFDSLEDVDWQEKEDGIELRRKIRLRNYGSQSSFAKLEMKQKQGSNQKKRSLRLTRA
                     DAQLLIKGDKSILLTYPDRFAAECYSRMSMQLYQPKTVIEYQRKAFVAKENNIRITFD
                     HHIIGSETNADIFSDHLPQNYLLDPYLVILEVKYNGFLLSYIKKLLESVNGSELSASK
                     YCMGRAISKHYRF"
     gene            complement(42230..42865)
                     /locus_tag="TV191_000256"
     CDS             complement(42230..42865)
                     /locus_tag="TV191_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zf-HC2 domain-containing protein"
                     /protein_id="HEL1506808.1"
                     /translation="MKYDCELIQDLLPLYVDDTLSDYSRAVVEAHLTSCKDCQTDLAD
                     LRQDYSKVEEELQEYQAEVCAFSRFIRKQRQQMIVATISICLVTGILSSILTAHRIRA
                     PYDYVAIDVGEHTQLNKEGLLSTARTTAKDHVALVYKHKAQKVNGSFEISELQARKIQ
                     QQLKQAMLKEANATDISSRQLDQSQKRLSCNQDDQLVYIISTDGRIYYFGR"
     gene            complement(42855..>43316)
                     /locus_tag="TV191_000257"
     CDS             complement(42855..>43316)
                     /locus_tag="TV191_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HEL1506809.1"
                     /translation="RFVNKLCCYQNSLSDDITQETFLKAYRNIAKFSGDSSIKTWLFT
                     IAKNTFFTEIKKKKYENMSMESLEIVDAKGHDEPLDKIARRELLEITLTIIFNLPEKM
                     QAVFLARIYSGDSYEKIAKDIGITVSSAKVLVFRARKHIKRQLREEYGYEV"
BASE COUNT        12801 a         9960 c         8189 g        12366 t
ORIGIN      
        1 tacaatgaaa ttatgacatt atggctccta aataagttgt tttgcatttt attattttgg
       61 tgatggattt gattaaaact agaaatcata tatctcctta tatgatcatc acttgatgga
      121 ctgctcaact gtctgataca agattaagcc ctttcttctt agttaacagc taccaaagaa
      181 aggtaaattg gctcctttat actaaattag agatagctaa aaacatctca aatactcttg
      241 acaaaacgtc atgactgtct tatctagcta gattagctaa cataaggcat taaaaataga
      301 cttagaaggt ttctaagtct acagtcgatc tctattattt gccaagcttt gccttagcag
      361 catcagcaag ggctgtaaaa gctgctgcat cattcaccgc taaatcagca agcattttac
      421 ggttaacttc gatttcagca agctttaggc catgcatcaa ttgtgaatat gacaagccat
      481 tcatacgagc agctgcattg atacgtgtga tccatagctt acggaagtca cgttttttct
      541 gacgacggtc acgataagca tagtaataag aattcatgac ctgctctttt gcagtacgga
      601 acaagatatg ttttgctcca taataacctt tagctaattt caaaatacgt ttacgacgtt
      661 tgcgtgatac aacgccacct ttaacacgtg ccattaatat tctccttcaa ataactctta
      721 taattctagt aaatacctgt tacaaccctt aatcttaaag gccagtaacc attgctttaa
      781 tacgcttgaa atctcctgca tgcaccatac ctgctttacg aagatgacgg cgttgctttt
      841 tagtctttcc atggaaacgg tgtgatgtaa aggcacggaa gcgtttcaaa ccgcctgaac
      901 ctgtacgttt aaaacgttta gctgatgcgc ggtgtgtttt ttgttttggc attttaatat
      961 tctcctctta acatatagtg taatatgaca attacttctt gtctgaaatt ggtgcaagct
     1021 gcataaacat ttggcgacca tccatttttg ctctttgctc aataatagca atatcttgag
     1081 ttgcctcagc aaaatcagcc agtaccttag caccaatctc cttgtgagta atcatacgtc
     1141 ctttaaaacg gatagaaacc ttaaccttat ttcccttttc aaggaactta cgaccattac
     1201 gaagctttgt ttcaaagtca cccttgtcga taactgggct aagacgtact tcctttacag
     1261 ttacaacgct ttgctttttg cgttgctcct tttgcttttt ttgatactca aatttgaact
     1321 ttccatagtc cataagcttg gcaacaggag gaacagcttg cggctggatt aaaaccaaat
     1381 ctacatttgc agcatcagct aaagactgag cttcagataa tggtttaatg cctaattgtt
     1441 caccttcaag accaacgaga cgaacttcgc gaacacgaat ctcatcatta atgaatagat
     1501 cttttttagc tatgatcttc acctctttat ttttttagag aaaaacgaaa gcggacttaa
     1561 tgaaccaagc ccgcacacat aatatcccgt aggaatttga catgtagggc cagacaacct
     1621 aggtcgcaag gcgagaagct ctcacttctg cttttctcat tattgacatt ctaacaaata
     1681 aatcatgcca tgtcaattat tttttctgct ttttcctgaa taaattggac aacagctgaa
     1741 atcgtgatac cggtagtatc aaagataatc gcgtcatctg ccgcctttag cggcgaaact
     1801 tgacgatgac tgtccttata atcgcgtgcc gcaatctcag cctttaaggt gtcaaaatca
     1861 gctgcaatcc ctttttcaat attttcctga taacgacgct gcgctctttc ttcaacagaa
     1921 gcaatcaaaa agatcttcaa ctcggcatca ggcagcacaa ccgttccgat atcacgaccg
     1981 tccatgataa tagcaccagt cctagcaatt cgtcgctgct gattcaccag ctcctctcta
     2041 atctctggca aggcggacac ccaagaaaca ttattggtga catcattttg cctgatcgcc
     2101 attgtcacat cttggtctcc aagaaaaacc agttgtgagc catcagctgc ttttttaaaa
     2161 gaaattggac gctttgccaa ttcttgcagg attagattga catcttcttt gtgataacca
     2221 ttttttaatg cgatataagt cgctgagcga tacatggcac cagtatctaa ataggtgtag
     2281 ccaagatttt tggcaataat cttggctacc gtacttttcc cacttgaggc tggtccatca
     2341 atcgcaattc taattgcttt catcttttcc tctttaatta tttgatattg acctcgtcac
     2401 ctggattggc ataccagtag ccttgggtca tatgatctgg gtttagggcc tgtaattgct
     2461 caacagaaat tccagcacga gctgcaatag atgttgctcc ttctcctgct aatactgtaa
     2521 ttgtctttcc tgctgcctct gtagaaggtg ctgtttcagt cttagaagga cttgttgtgt
     2581 cactagctgc tgagctatta gagctcgctt ttggctttgt ttttggtttt gagctgacct
     2641 tctttgttgt ctttttctga gttgatgccc cgtaaaatcc tgttgtctca ttttgcttgt
     2701 tactaccgct gtttgacgta tagaagaaaa taaaaagtat ggcaacaata atgacaaaga
     2761 aaacacttaa caaggcagtc aaccaaggtg tgctaatgag tgctcctctt gattttcttg
     2821 ttcttgtcgc cttattgtca tcaacaattt tttcttccca tggttcttta gccatgattc
     2881 ttcccccttg ttaatttaac aaaatcatat tagaataata cctatgaaag tatctatcct
     2941 tccagaaaaa tgcattgcct gtggtctttg ccagacctac tctgctcttt ttgactatca
     3001 tgatgatggt atcgtcaaat tggctcagtc tgatgagtca agtcaactca tagatcctaa
     3061 tgatcatgat gccatcttag cagtaaaatc ctgccctact aaagccctta ccctcgagta
     3121 agaggctttt tttcgtattg gtaggcttca aaataatcca gtttaatgaa gttatctagt
     3181 aatataacct ctcccttaaa ataaggatta atcgctagat catctaaaaa atatttttta
     3241 ggccattttc tcatgtaaaa aaggtagctc ttatcaccaa caaatagaca aaccgttgat
     3301 ttagtaacct caattttggt aattgaggca atcatcagtc tgtgcggagc aaatagcttt
     3361 aaagatacga tcttcaagac accattattc tcaattacaa aataacgatg caggccaagt
     3421 cccactaata tagcaaataa agcaaacaag acaaaaacac gactcggtat ttctgttctt
     3481 tcatacaata aggacaggcc aataaaaata ggcgcaacag caattgacca ataaataata
     3541 gaccaagaca gctctggctg ccaatgatac cttactttac cgaataattt aatcatgctt
     3601 ttccatcacc tccaatccgt tctgagcatt ttgggtgatg ttaagccttt tggacaatgc
     3661 caagaatcac atcaactgcc ttttccatcg tttgcagact cacaaattca aacctgccat
     3721 gcatattttc accacctgca aaaatatttg gcgttggaat ccccataaag gaaatctttg
     3781 agccatcagt accaccacga atcggctcga taactggctt aatagctagg tcctccataa
     3841 cagccttagc tagattcaca ggtgtcatgt ccttttcaat cacctttttc atgttatagt
     3901 actgatccgt cactgttaca aatacacgct ctgctccaag ctgactattc atctcctcag
     3961 ctagctgtgt tacaaaggcc tttctagctt caaaggagct atcctcaaaa tcacgaataa
     4021 tataagaggc ctgtgcttct tctacagtac cagacatgct gtgtaggtgg taaaagcctt
     4081 gatagccgtc cgttttttca ggacgatcgt caactggtaa ttgactatgg aaatccattg
     4141 ctagctgcag ggcattaatc atctgatttt tagctgtacc agggtgaaca ttgcgaccta
     4201 acaccttgag ctctagggct gctgcgctaa aggtttcata ttgtagctcg ccaagcggac
     4261 ctccatcaat agtataggca aagtcaacat caaaagcatt aacatcaaac ttatctgcac
     4321 caacaccaat ttcttcatca ggtccaaagg caaccttaat gtcgcaatgc tcaatctgag
     4381 ggttggcaac aagaaactca atagccgtca tgatttctgc aattccagat ttatcgtcag
     4441 ctcctaaaag ggttgtgcca tcagttgtaa tcagggtctg tcccaaatat tggttgagat
     4501 ttggaaaatc ctctgggcat aaagaatagc ctgactgacc aagcttaatc tccccaccct
     4561 ggtagctctc aataatctga ggggctactc cttctgcatt aaaatcagca gtatccatat
     4621 gcgcaataaa accaattttc cgagtcaatt tgctgctgtt agctggtaag cttccaatga
     4681 ggtagccatt agctggattg taatgaatgt cctgtaggcc aatagcttcc atctctggct
     4741 ttagcactgt tagagcaaag tcagcttgac tcttggtgct tggagttgta gtgcttgctg
     4801 gattgctcct tgtgttgatt tttacatagt tcagaaatcg ttctaataaa gtttcgtatg
     4861 tcatagatca cctcgataag ttttcgttac tattatagca taaaaggacc taaaatactt
     4921 gcctaagctc agttttttac agtgctttat ctgttctgtt acagttgcgt tctcataaaa
     4981 agacagctgc caagaaagct cttgacagcc ttgattattc atcagcccat gccttaatcc
     5041 tcataaccat ttgggtgctt gctttgccat ctccaagtat ctgtacacat cctttctaag
     5101 ccgtactctg cagtccagtt aagctctttt ttagccttgc tagcatcagc atagcaggct
     5161 gcgatgtctc cttgacgcct tggtaatatc ttgtaaggaa tagacctgcc aaccacctga
     5221 gaaaaggctt cgataatatc tagcacagaa tagcctgtac ctgttcctaa attataaata
     5281 gataggcttg gctcttcagc aaactttgca agcgcagcga cgtgtccttt agccagatca
     5341 acaacatgga tataatctct aacgccagtg ccgtccttgg tctcataatc atcaccaaaa
     5401 acgccaacac aatccagctt accaacagct acctgagaaa cataaggtaa taggttgtta
     5461 ggtatgccct taggatcctc tcctaaatca ccagactcat gagctccgat aggattaaaa
     5521 taccttaaca atacaatatg ccactcatta tctgatgcat agaggtcctt gaaaatctcc
     5581 tctagcatca gctttgtcct accgtaagga ttggtcactg atagtggaaa ggtttctaaa
     5641 ataggaacgg tatgcggatc tccataaacc gttgctgagg agctaaaaat gatcttttta
     5701 caattaaagg ctgtcattac ctttagtagg gtcaatgtgc cagagatatt attgtcgtag
     5761 taatcaagtg gaatcctgct tgactctcca acagctttta gccctgcaaa gtgaatgaca
     5821 ctcacaatag gatgcttact gaaaatatct gttagcagct gttgatcgcg aatatctccc
     5881 tgataaaagg tcacttctct tccagctatc gaggcaacag cagctaggct tttaggattt
     5941 gaattgcaca aattatcaac cacaacaacg tcatagccag cagctagcag ttcaacacag
     6001 gtgtgtgacc cgatatagcc tgcaccacca gtaactaaaa tacttcctaa cattgattat
     6061 atacctgact ttctaataat tactaatatt ataactgatt actcccaaaa agtatatcta
     6121 tcatttcatt ttaaagaaat caggataggc attaatgtag cccttgcctt caataagatc
     6181 atattctaac agctttaagt cagaggccac ctgcttttga gcagcagtta gctggctgtc
     6241 atcgctattt ctggtatcca agacatctgt caaaagagcg tagtaaggag acaccttgga
     6301 atccgtatgc tctagcaata aagaggtaaa atcactggaa ttaacacgag gtctagccaa
     6361 tttgttggtc tgatgattgc tccagatgaa ataatctgtt aaatatttga cctcctcatc
     6421 attcttaaag acctgatctg gataaaagcc aggtaaatga tcaccataaa acacaactgt
     6481 aataggcttg tcaacctttt ccagtgctga taaaaaggcc tttgttgact tgtcggtaat
     6541 gcttaataaa ttcacataac tttgcaggct atccgtctca gactggtcca gtcctgctag
     6601 gctaacatca acatctctta gctctgtgta ccaagggcca tgattttgca tggtaatcac
     6661 tgaaaagaat tgacttcttt tggggttaag ctggtctaaa atattgtcat aggttgactc
     6721 atcactatag cttgagctca ttcgtatcaa gtgctttggc ttgtcagctg aatcctctgt
     6781 ggcaatgaag gtatcaaatc ccaatttgtt gtaaacgatt tttcgagagt aattgttggc
     6841 gctcgcaagg tgcaaaacaa tcctatcctt aggcgaaaag gcattactaa tggcaggcga
     6901 aaacttcaac ttaggaaaga catcagaata caaaatcgaa actgttggat tgaggttata
     6961 ttttggtagg ccaaataggc tttgaaactc catattagct gtaccgccgc catagccatc
     7021 agaggtcatt aggccactcg ttgtggtttc catgatatga tggatctctg caataggatc
     7081 cttggccaat tgaaccccag aaatcctagc tgggtcagca aagctctcac tcagtatata
     7141 aatcactgtt tgatcagaaa tacgctgatg cctttgctta ttgatatcag cagctctagc
     7201 ttgatatttc tgataaatct tttgcatagc gctcttgcta tagcctgaag gctgattaat
     7261 ggtgctggtg gtaacctgct tgaaccaaac aaagctcaag gattgaaacc ttgcattggt
     7321 tgtaagacca taccagtcaa tatcaaagac attgtagact gatgacagaa ctggaatacc
     7381 ttttttgatt tcaccatctt tattttggct aaatacaaaa aggatagagg caaataccaa
     7441 aaggatagag cctattgaca tcagtctaag ataaagcgct gataggatct tttctctaaa
     7501 gtatctttta tacaaaacat agatcagcag acccgacaag actagtatca aaataatact
     7561 aatgatttga gtcagactaa tgtaattcaa gaaaaactta atctctttga tccatttcaa
     7621 atctgaaaac aataaaggct cacttcgctg cttgtatttt tcaatattaa caatactgat
     7681 taaagctccg atcaccgtat tgacaaataa agcaatgata tagttgttaa tgagcaaaaa
     7741 caccagcaca aaaaagaggg tcaagacaag cacctgaaac agggttgcac ctggaataat
     7801 cactgcccca tgaaaatcac catatgctgt gatcccagcc tgaataaagt aattaaagat
     7861 gatccctaaa aataagctgg tcactagagc taatctaaga ccccatcgct tgctcaaaac
     7921 ctcgataaag gctgtgacga tgaggtaata aaccacaaac gtcagcatat aagagcaaaa
     7981 gctatactta aagagattca ggctaacaag gtttgactga ctatctaaag gccaataatc
     8041 attttgctta atcacagtct taaataaaga gctgttcagc gttaagactg aaaaagcctg
     8101 actaagtaaa atgacttgga ttcctctgtt tgattggtag tccttcttaa acaggtattt
     8161 ttttaagaga acccctaaaa taagcaggct gactaaagct gccagactga gtagcatttc
     8221 ctgaatcgta cgattactga tggtaaacct gctgttgttt ttattgatgg ctaaggtgat
     8281 atagctatta gcaacagcat agtagctact gacagctaca gaaacaataa gcagctttga
     8341 ggaagcatgc ttgatcagca aacatgccat tccagctatt aacactaaga caagccacga
     8401 accataagct cccttattta acgtgttttt gcttaccgca aaaatagata aataaagaga
     8461 tgaaaggcta aacaatatca tatcaagcat ttctagatca actaactggc gagcttttga
     8521 aattatcttc gttattataa tggtcacacc ctttcctaac tgctaaaagc tagacattac
     8581 tctctgactc agaagcgatt acctctgtta ctaattgacg aacagtgacc tcccaggtaa
     8641 agcctgaaag cacctgctga tgaatggctt cttgcaggtc acaccgtttt tctttgtgct
     8701 caatcaaatg atccaactgc cttttaatat cagagactgt atcatcaatg atgattccct
     8761 gtgacgggct cgttatcact tccttgacac cacctctatc tgttgctaat acagcacatt
     8821 tcaacatacc tgcctctaat acagctgtcg gaagcccttc agcatagatg gacggattaa
     8881 caaaaatatc agattgagac agcaaagaca tggtctcagc aaaattcagc ttgcctgtaa
     8941 agatgatgga ctgatcctct ttatagctat ctcttagtga agcaagcaag ggaccatctc
     9001 cagcaaccac caagacagcc ctgtccttat atgtcagctg ctcaaaagcc tccagcagca
     9061 aaagaatccc cttttccttg atcactcgac ctgcaaaggt aataatgacc ttatcctgca
     9121 aagctggtaa ataagccttt gacttaaaga cctcataaag atcagaatca actgaattgt
     9181 agatgacgcc tttggctttt attccaaagg tcttgagcca tgccatactg cgcttagaca
     9241 ccgcataaaa gtcgggctga taggctttga caaaaaaggt aattacatgc tcatagactt
     9301 tagcaaacaa gtctagtagc tggtgacctt taacattttc gcccacctga acatagccac
     9361 caccatgctc gatcacaata ctagggatgg cttttctttt ggctagcttc aagcccatga
     9421 ggcttgtcaa ataaaatcgt gtattgcaga tcacaaagtc aatacgttct tccatcagct
     9481 ccgccagcat gctatgatac agatcattct tatctaaaat cggatagcgc tgcttaaata
     9541 gctgctttga aggaaatcgg taataagtaa tggcttgatc tctttcaata gggctcagct
     9601 ggtggctgtt gctggttaca atgatgatac ggtagcctag gctcactaat tgttgcgcta
     9661 ttttttctgt ataccgctct actcctccta gatgagggct tgtaaagccg ctaaaaatgg
     9721 ctattgtttt caaagctttt cccttcttat gtataatatt gcagcattgt tcgagtaatc
     9781 atacctagga tcaatagcaa cgagccaata agaacctgtt tattacttaa taggccttgg
     9841 gccttttcaa ggtatttgtt attagaggcc agcaagacca acactaaagg gatcacaccc
     9901 aaaaagtacc tatcttgaac ccctagcaca ttaaggtctc caactggcgt aaaggtcaaa
     9961 taaaggctaa aggtaatacc gcctattatt cctaaagaca tcaatcccat accaaagcga
    10021 gataaggtcg gcagctgaag cttgttggca ttagtgatga caacagcaaa ataataaacc
    10081 atactaattg gcatgagctc taccataccg tatgataaag ggccaaacat gtaaatccct
    10141 gaaggattaa ggatatgagc caacgtgtgt cttagcagca taaagccata tactataggg
    10201 ttccttaaca cagtcagtag ctgctcttta gcattgacct tctggagaaa gtcagccata
    10261 tccacctgag gtgacttgat ttgaccatat acctttaacc aaaaaacagt cacaaccagc
    10321 accgtcagaa ttgacaacag ctttagcaga aacgtgcgag aggcttttgc tccaaattga
    10381 cgtgaaggga taaaaagcag caacaaaatc aataaaatat aaggcagctt agtaaaggta
    10441 atgattgagc acagcagggt ataccaaaag agcttggata agggaatctt ttcagttgta
    10501 gccatctgaa caaataaaga aatcgtcaga ataatcaatc caatagagac acaatcctga
    10561 ttataagaac cagcaagata gatattcatc ggaaggagac ttcctacagc aagcagctgc
    10621 ttgcctgctg tcagcaatcg taaggcaaca aaaaccaaga tggcataggc aagaacatta
    10681 caaagcctac ctaaaaggta agataagccc atggtcaagc ctaagctcct tccaataaat
    10741 aagcctatta cctgtggtat gtaggcaaag ttataatagc catttgttga gcgaatttcc
    10801 ttaaatgaaa tagcctcatc tgtatggtct ctgctccaca gctgaaagcg taagggcttg
    10861 ccattgttgt ggtccataag attaatgtca tcagtcacca gcagctttga gtcatcattg
    10921 gttaaattaa gatttccctc agataagtat aaggctcttg caaagtgaac cctctcatca
    10981 ggaatatcat tgatcggtga gatgaaggca gagacagaac ccataaccac aataataagc
    11041 actgtcgcat attccatatt tgaaggtaaa aagataatca aaagcgcagc aattgcaact
    11101 aatattgcta aaaatttaat gggtaaatcc gttgattgcg tatataaaag cagcaacaca
    11161 agaaaggcac caagtaaaac aagcaaagcc ttactcgcct tttgcaattt gtcaaataag
    11221 gtatctaaca tatcctattt ccttttttcc ataatgtaca agccatatga caatagcagc
    11281 caaatcatca ttgaaattat aaaaccatag gtaactccaa tcaccccaaa gcttctagcc
    11341 aaagaaccag tgatggctag tgaggagata aaggatacaa cataaggtat cacaagcaag
    11401 tgctgctttc tgataatggt aatcaaatta tcaatataag tggcaaaggt gctgataatc
    11461 cctccaaaaa taagaagcat aaaatcaagc tggtaatgcc ttaaatcaat accataaaca
    11521 agcgatagca ccggcagccc cacaaaatag ctagcaagca agatagctag gcttgctaat
    11581 agcagcacta gactgagacg acgctctaat tgtgcaaagc tcttcttgtc ctcttttgaa
    11641 tggtaaatgg ccagctgagt gatcataggc cttaaaaaca agaaaatcag gttaatcata
    11701 aaaataggca taaacaaaat attaaattct gtttgaacac cggctgggat cagctgcttt
    11761 gagtaaagct gctccaaaac aaacttgggc tggttgtaga tataaatgag taaaaaacca
    11821 tttaaaaaga ggggaaagct ctccttcaat agccctaaga tgctttgagc atcaatacga
    11881 cgctcaaggc tcgtaaagga aactgaaggg gttatgtcaa atagcacaat acaagccact
    11941 gaaataagac atatcacgat caaagacagg actagctgct tggtcagaac cagacagagc
    12001 gtaaagccaa gaatcaccag catatttcga taaaacaagg atttgccggc aatatctaag
    12061 cgctctcttt gttgaaacat tccttgaaac acatcagaaa tggcatctgt gcaacgatac
    12121 aagcaaatca accaaatcac tagcccctta aacccactat agctccccaa ataaatatag
    12181 agcactgaaa tggctatcat caagaaacag gtgactagtc ttgtataaaa atagtctttg
    12241 aagcggtact tgtgtaatat atccgttgat tggaaatttc taatctgaaa taagccaata
    12301 gtaatcagct gatttccaat agcataggca aagctaaagg tatctgaagc tgatttagat
    12361 aagacccgag acacaatcat cagtaaaatc actgatatta gtgctgtcga gctggttccc
    12421 aacacattcc aaataaaaat cgactgatcc gattgaatcc tactgctggt tttcatcttc
    12481 ttcctgcttt tccttctcat taagggctaa atactgaatc atttttttaa gcttaatctc
    12541 tgtccgagac aatttttgag tgataaaaaa ttggttgatg atgagtaaaa aaatgattga
    12601 tagaaaaaca aaatttgccg gcgattcaaa gcctagcagc cttgaaaaat aaaccgcagc
    12661 atttggaaac agtgacagca aaagcactat taaagagaaa aagagccaaa aaaagctatc
    12721 ttcaattaaa attttggatc tgcgaatgct atctagtata aacatggctg tcaataatgc
    12781 aacaatgatc aaaatcagct gtaacccaat aaacatcctc ttacctcttt ctaaagtttt
    12841 gaattaaaat aatcgaaata aacatgtgaa ccatgtattt aatagatcta gaaagagtga
    12901 ggtagctttg accagccagc ctatcattca tttgcacctg aacctcactc accctatagc
    12961 cttgtcgaat aagataagag atcgtatcag gctctggagt atagttaata ttagttgcaa
    13021 aaatcctgat cagctcctga ttaaacattc tcataccaga ggtcggatcg gtaatacgct
    13081 ttcctgtggt tagcttgata aaaaagctaa taaggctatt gcctatcatt ctcaaggatc
    13141 tattcttttc agcactgaca aaccttgatc caatgacaca atcagcacca gcattaattg
    13201 aatcgctcaa agcctcaata tactctggca agtgttgacc atctgcatcg aactggagtg
    13261 ctttagcata tcccttttta aaggcatatt taaagcccgt ctgaatagca ccagataagc
    13321 caagattttc cggcaaatca atgatattgt aatggttatg atgacagatc tctgatgtcc
    13381 gatccgaaga gccatcattg ataatcacat aatcatattg aggaaaatgt cttttgatat
    13441 tttccactac tttttcaatc gactcctctt cgttatatgc tggaatcatt accaataagt
    13501 cttttttcat atcgtcaaat attctctcta ttcattcgtc taaacgcgtc tttttagcaa
    13561 tcgctttatg atataacgga tagccttagc tggcccaatc acaatatatt ttaaggctcc
    13621 ttttatacct cccatatagt caaaatcgac ataggtatgt ggcacactgc cttcacgcag
    13681 gtttaagagc ttattatcaa taaatggtgt caatagcttt tcatttcttg aaattctaaa
    13741 atcatagtgt ctgtcccaag caatataaat taagagacgt tcaatggcat gcaggatcga
    13801 attttgagac agaggctctg ctggaatatc agcctcactt aggtctaagt caaacaaggg
    13861 ctttaaggca tcgtatttaa accaaacaaa ggtgccatag ctcatgacaa aggtatccat
    13921 cgtctgaaaa tcaatgcgtt ttgtaagccc cattgcctgc caaagctgat tcatttcagg
    13981 ggcaataagg tgctcattcc aagcgtcaac aattttatta aaacggaaaa aacttggaat
    14041 atctgctatc acaataccga tagcatcagc agccagtgct gttaggattt gatccgccgg
    14101 cttcaccatc atatcaatca attcagtgcg ccaggattgg cccgcccaaa aatctgcttc
    14161 ctttgatttt ttggtatgaa aatgcccaat ataatcatat tgagacaatc gttcctttaa
    14221 ggtcagcatt ggcaagacat ctcgaccgat atttcctgtc accaatatgt cagcacttgc
    14281 cccgctttct cgtagaattt ctttaatctc agccttttta gccttgctat cggtcgttat
    14341 gagcaagtca taatcaaaat gaaaatgact aaatgcttct aaaaactctg acaataaatc
    14401 aacataaaaa acatgaagat gaacagcaat tttcttgctt tgatcaatgc ttatcggctg
    14461 ctctggcagg tatttatgtg ccagaagata cttagcatct ggtggatgga cctgcgacat
    14521 atgatccaca atcaagctgg cagggtatgt cgttttttgg tcaataaaat ccaaaaggta
    14581 aggagcaatg tgctggttag cgtcaatagc cttaaccttg ataaagggca catggtgctt
    14641 taagatggct gtcggattgt aataagagaa atccgcatgc agcatagagg acgagtcctc
    14701 cttggtcgta tcaaataccg tcttgtatcg aaagccagcc tccacaaaga cagtggttat
    14761 tctggtttca taattgtgga tcacatcttg aacgtctgtt agctcaacga tattttccca
    14821 aaactgccta aattccttac tatgaacgag ggattttttg aagctgataa aatagctctg
    14881 aatatgctct ttaaaggcct tggtcgctcg attgttggtc atgccccaga aatcaactgc
    14941 ttcatctgct tcatatttga gataataagg cttcatatcc caaagcggac caaagcaggt
    15001 atcgttcata atcgtgattg agtcaaagtc aacaaggtgc tcacagccta aggccttcat
    15061 accatcatgc caagctgcaa aatcatagcc tttattgtgt cgttgaataa actgatccat
    15121 caaatgccgc tgttcaagct gctcaaggtc ctcttgatgg atatcactat ttgaaataaa
    15181 gacaatcttt gaaaacaagg ctctcatctg ttcgagctgg taataaacat gatcgcttac
    15241 cttatgatat ttattgaaat gcacatacaa taatagacgc ttcatttttt cctcctaaaa
    15301 agctcaagca gctttgatag gtacctccaa cgacgtgagg taaccacaca attgtattga
    15361 tgggttagcg cttcaacctc ttgcctttga tgatcaagct gctgctgtag ctgatctatc
    15421 ttctctgcct gtagagcctc ctgatctgca agcgtctgtc gtaattgatg aatggtatga
    15481 cttaattgat gaatccgaat ttcattttta gcgtcctgct ttagtaatgc ttttgcaata
    15541 gcttccatat tggctgtagg gtatttagac aaataggaca gctgggtctc caacaagcct
    15601 tgaatacggc ccagcatttt ttcctctgct gccggccttg aatctgaatt atccgtcatt
    15661 cgataaacag tggtcgaatc cttcaaatag gctagagagg ttgactgaaa cagctctaat
    15721 tgtatgtcaa aagtgtcgtc tgacgtctcc aaatcaatgc gttgattaac tgccctcatc
    15781 agatcagcct ccaccagcca ggttgatgac atggtcattc cttttaaagc aagcattttc
    15841 tcgtaggtgt ctgttaaggg agtaaagcca ctttcaaagg cattgctctg aataagcttg
    15901 ccgtcagtat ctacaaaatc aaagtcagta ttagaccatt ttgaatctgg tgagctatcc
    15961 agcaaatcaa cctgcttttg tagcttgaga gtatcagtcc aatagtcatc accatcacat
    16021 ctggcaatat actgtccctt tgcctccaaa caagccttga cccaggttct tgcaatccca
    16081 agatttacct cattaacgat gagtcgtata cgatctggaa agctggcttg atagtccatg
    16141 aggatctgtc tggaatagtc tgttgaagcg tcgtcaatga caataatttc aacatcaaag
    16201 ctggtctgtt gggctaaaaa gctgtctaag gcctctgaaa tccaaggccc cttattataa
    16261 ttggtgcaaa taatagaaac ttttttcata ggatgctttc taatgacaat tattgattaa
    16321 tgagccagct accatttctt tgatataagc cactggcaga gtccaaagca gacaggtcat
    16381 ctggagcaat atcgtttcgt tgaagcacga ctaatgggga atgattagct gttaaaaaga
    16441 gcagcatttg cccgttttga tcgcgaacag tcacctcaag ctttaatttg atatcattta
    16501 ggtgtgagag ctgacactgg taggatatgt tcttatgacc aggaccactt gtcggttgat
    16561 cctgtgaatt gtcattatat acccaaatat tgcggtcaat atcagtcaac gaaaaggcaa
    16621 cataggtagg ctcgtccttt aagacatgat aggaaatctc aaaggaaatg ggctcatctg
    16681 gactaaggct tggcttagag gtcaacctca cctctaactg gcttgccaaa tcagacacag
    16741 gctcagcagc agctccttgc tcagcatttt tcaattcagt attatcaaca ctgtattggt
    16801 tagcgacatc aaagggttcg ccgtaagcct tgacaaggcc attttcgatg aggactgcgc
    16861 gattgcagta ttttttgaca gcccccatat catgggtcac tagtatagta gtcttgccgc
    16921 tctccttgcg ctccatgaag tagtcattgc attttcgttg aaaggcctca tcaccaacag
    16981 ctaacacctc atcaagaatc agcacatctc cctgtgcctt gatagcgaca gaaaaagcaa
    17041 gacgaacctg catgcctgag gaataatttt ttaatttttg attcatgaaa tcatgcagct
    17101 cagcaaagtc aacgatatca tcatacatat catcaacctc ttctgtggta aagcccagca
    17161 ttgcgccatt catgtagaca ttttcacgcc cagtcaactc aggattaaag ccaacaccaa
    17221 gctcgatgaa ggacaccatt ttcccctcaa ctgtgacctg tcctttttct ggaacataaa
    17281 tttgagaaat aatttttaat aaggttgatt ttccagagcc atttcgtcca acgatgccaa
    17341 aaaaatcccc cttatacacg tcaaagctaa tatcccttag cacatgctgc tcggtatagc
    17401 ccttaatgcc tttaaaacgg ttaacaagag cagtacgaaa gctcttggtt gcctctgttg
    17461 gcagcttaaa ggacttactg acatgatcaa ctgttactgc aatttcttta ttagccatta
    17521 gataatctcc gcaaacttct tagcattttt attaaacact gctaccccaa gtgctaatag
    17581 gacaaatgga atgaggtaag gaatgatgat atagcaccaa tttgtcgaca tttgccaaat
    17641 ggtcacatta gctctgtcaa tcagcagata ccgcaaatct tgaataatct gtgctaaagg
    17701 attaagcatc aaaatcttgg cagcaagagg gtgtcggtca aacacaaagg taatcgggta
    17761 gatgatggga gtcacataca tacctgcctg caatagaacc tcccaaacct gagccaaatc
    17821 acgataataa acaaagacgg tagaaagcat caaggccaca ccaactgtaa gaacagccag
    17881 ctcaacaaag agtggtaagg ccagataagc gtgaggagat aaagtaactc cattgatagc
    17941 tgcaaaaacc aaaaccacta ataggttgat tgaaaagtta atcaatgctc ctaaaactgc
    18001 tgaaaaaacg atagtatgct ttgaaaaatt caattttcta agcaggtctc ctcgcgatac
    18061 aatagagacc attcccatac tggttgcttc tgagaaaaag gaccaaatca cattggcaag
    18121 taaaagagca accggaaaat gaggaacgtc accaccagtt cgcaaaaacc tgataaacac
    18181 caaatacatg atggtaaaca tcatcaaagg ctttaagata gaccacaaat aaccaatagc
    18241 actgccctga taccttagtt taaagtctgt tttaacaagc tctttcaaaa gaatacgatt
    18301 ctttttactc aataattcca ttattctttt ctcctatagc caaatttggt catgatcaat
    18361 gccataaaaa caagggtatg aaaggcacga tttttccgaa agccatacgc tttgaaatca
    18421 gacagacgct gatagaaagg cctatccaaa agccctacgt aagcctcaat caatcttctg
    18481 tcagccggat ttagctgcaa gtctagcaat tgccttgctt gatgttgact agaaacaata
    18541 agccaccaat acttctctat gagcttatgg ggcttacgcc actgcttcag tcgcttagac
    18601 caggttcttg cccctaaaac attagcatca tgctgacgat agagctctgt tgccacatct
    18661 agatacacaa gctctccctg cgctgctgca atcaaggcta aataccaatc atgcatcacc
    18721 acatgctcac agctcaccca ctgctctgcc agcgcgtgat taatcatcat agtgccgcct
    18781 gtgactgtgt tttcagtcaa ctcctggact agctgagtat tagcatgatg tgattgtgtt
    18841 tggatcatac tctcatgacg tacttctaag tcttgattga ccacctttag gtctgtgtag
    18901 actagtaagg gctcgcttat cttgtgcttt tgcgcttctg ccagagtaag ctctaattta
    18961 ttgtctaacc acacatcgtc ttggtcactg aaaaaataaa tatctgcctt ttcatatgtt
    19021 aaaagggtgt gaaagcttcg aatcacaccg aggttttcct gcacatcagc attaatcaag
    19081 caaattctcg gatccttttt agcaaaagcc tgaatgatgg caagcgtttt atcagtagag
    19141 ccatcatctc tgactaataa ggtccaatcc tgcaccgtct gcctttgaat gctttgtatt
    19201 tgctctgcta aaaaccgcgc cccgttgtag gtagacatta aaatattaat cttcatctaa
    19261 aaataaggcc tcatactctc ctacaatttt ctcccaggta tattctttgg caatgatttg
    19321 cttagctctt tctcccaaat cagcaaacga ttccttttga tcaaccctgt taatcagtcc
    19381 agtaaggctg cccttttctt ttgtccaata aagggctgct gttttagcaa ctgattgatt
    19441 aaaggtcact cccaaaacca aattaagctg ggtatgggct agggcctcca aaagacctgg
    19501 attggtacct ccaacctcat gcccatgaat ataagcaaaa gcatgctcac gaatataagc
    19561 taaaagctgc ttatcatact gtgttccaac aaattttaca cgcgcgtcct tatcacagcc
    19621 agttgcacta accagccgct caaaataagg atttttgtca tggttgcaaa taataaccaa
    19681 atcccgctga gtagatgatg ccataaactc tctaatggct gtttcatagt tgttttcagg
    19741 aacaaagcgc cccaaaatca aatagtattg gttttctgtt atctcaaatg tttgaaagta
    19801 agttctgact ttttcatctg atgtagacaa acaagaccgc cctatttctg tcccataggc
    19861 aataaaagtc gtttttgccc aaggataaga ctttttgatg taggcttcaa tgccaatatt
    19921 atctgagatg accaaatcag catgctttgt catttgcttt tcggcgtatt tcaggtattg
    19981 ctgaacaggc ttagaccatt ttgaacgctt ccattccagc ccatcaggat taatcaacaa
    20041 acgcccacca cgctggtgaa tctgctttgc aaagggggca ataaagcctc caatggtatt
    20101 gcctagaaca taaaaaatag gcttttgaat atgataccta tcaatataag ctaaagcgtg
    20161 actaatagcc atcatatcat aagcaatcac tctagctgga ccgagcttag gaggattgat
    20221 ataaaaacaa tctgctccct tgtacacaaa atgctccttg tgcttgctat cgctcaagca
    20281 ggcaatatga taggtaatgc ttttgttggt ctgattagtg actaattctt caacaaaggt
    20341 ctcaaaacca ccatactttg ctggtaaacc gcgacttccg atgatgaaaa catcctgcat
    20401 agcacactgc cccattctaa aatataatta gtagtattat accatataaa caggtcttat
    20461 gcgacataaa atccatgaaa agagagccaa tctcctagat cagctcttta gtgctatcgc
    20521 ttattcattg ctgttgcttg taaaaagcct ccagggcttc ttgccaggta ggaatcacaa
    20581 aaccagttgc cttagcctta tcaagattca tggttgagtt aaagggtctt ttggctttag
    20641 caggaaaagc cgatgaatcc acaggcacaa cctcgacagc tgtctctttt aagatttctc
    20701 tagcaaaatc ataccaagtg gtgtcttctt tagcatcatt tgacaaatga taatagccat
    20761 aaggcttgcg attgtctgct agatgacaca taaactcagc caaggtcctc gtccaggttg
    20821 gacgcccatg ctgatcattg acgactgtca agcgagagtg ggtcttagca aggttttgca
    20881 tggtaaacac aaaattcttg ccataatgac caaacaccca tgcggtacga ataatgtaaa
    20941 attgcttggt atatcgctca acagccagct cacctaagcg cttagcacga ccgtatgctg
    21001 tttgaggatc aggagtatct gtttctagcc attcctgacc agctggcttt tgaccatcaa
    21061 aaacgtaatc cgttgaaata taaaccaagg tcgccccgta gcgctcacaa gccttggcaa
    21121 tatgctcagt accagctaca ttgatagctt cattcagtgc ttttccttct tcttcagcag
    21181 catcaactgc tgtgtaggct gcacagtgat acactaagct aggcttgacc tgagcaaaaa
    21241 cctcctctac tttagtcgcg ttggtaatat ccatttcagc aacatcaaca gcaacataat
    21301 cgacgcttcg ttcgtctaaa agataacgaa gctctgttcc taattgacca ttacttcctg
    21361 taattaaaat catcttttct cctttgtaaa ggtcttattt ctttgagcta atcacgcagc
    21421 tcactcccat ctaatcctaa gagaggcttt tttgatcagc tgaccctagc aagacctttg
    21481 ttgtggtatc gtatcagcct tgctttttat ctagctaccg aatacctagg gcaattctcg
    21541 catagcggct catcttttca acgctccaaa cagggtacca gaccaacttt acctcaacct
    21601 tggtcacctc tggaacatct ctcatcgcat catgaatatg atcagtcaac aaatccgcca
    21661 aaggacagcc cattgtggtc aaggtcatgt caatctcggt atgaccattg tcatcaaaac
    21721 gaatctcata gaccaagcct agattcacaa tatcaatacc tagctccgga tcaataaccg
    21781 ttcccaaagc ttcaagaatc cgatccttga tagctgcaac ctgctcttct gtgtatttta
    21841 atgtttcagt catagctatt cctttcactt ttttcgaaga cctgatatga tgccaagtca
    21901 aaaaccagcc caaagaccag cgcattcagc atacctatga tgccctaagc tgactaacat
    21961 tgatagcctc tttttagtca cccttacatt aacactagtc tttagctact ggctagcaaa
    22021 ggtaatctca taaaccagta actaggcttg gagtcgttga ccataggcca ctcaccgtca
    22081 aggagagata acgcatttcg ggctcgtctc ctatttttag ctcgccgtta aaaaggtcca
    22141 ccggaccttt ttaatcctca atgaagtctc tgagctgctt gctgcggctt gggtggcgga
    22201 gcttacgcaa agccttagcc tcaatttgac gaatccgttc acgagtgaca ttgaagacct
    22261 tcccaacgtc ctctaatgta cgcattttcc catcatcaag cccaaagcgc aggcgaagaa
    22321 cattttcctc acgatctgtc agcgtatcaa gcacttcgtc taattgctca cgaagaacca
    22381 cacgagttgt gtaatcaaca ggattttcaa tcacttcatc ttcaataaaa tcacctaaat
    22441 gactgtcatc ctcttcaccg attggtgttt caagagacac tggctcctga gcgattttca
    22501 gaatttcacg caccttatca ggggtcatct ccatacgctc tgcgatctgc tctggagtag
    22561 gatcctgccc caattcttga aggaggttgc gctgctcacg cactagttta ttaatggttt
    22621 ccaccatatg cacaggaatc cgaatggtac gtgcctgatc tgcaatagca cgagtaatgg
    22681 cctgacgaat ccaccaggtc gcataggtcg aaaacttgaa gcccttagaa taatcaaact
    22741 tgtcaacagc cttcattaag cccatgttac cttcttgaat caaatcaaga aattgcatgc
    22801 cacgccctac ataacgcttt gcaatcgaca ccaccaaacg cagattggcc tcagcaagac
    22861 gctgcttagc ctccatatca ccagcggcta ctgcaaccgc taaaaccttt tcctcatcac
    22921 ttgtcagcag cggcaccaca ccgatctcct tgagatacat gcgcacagga tcgttgacct
    22981 tggctgaatt acttccgata agctcctcgt ctgtcagctc ctctggctta ggctcttcaa
    23041 cgacgtattt agatgaggga tttccttcct tatctgtaat ggaaatgcca ccatctgtca
    23101 aacgctcaag caaatcatca atttggtcag catctaaggt aaatggaatc acgagttttt
    23161 ctgtgacctc atcatcagta gctgttcctt cctttttatg atgacgaata aactccgcaa
    23221 tttgaacgtt aaaggttgta atttcttttt cttttgccat attttcctct attccatttt
    23281 tcttttttca gcaatgaaac gctctaaagc ctctagagcc atctggtggt cacccttact
    23341 gctagattcc ctaatctgct ttccttgcct atgcagctct ctttgcttta gcaatgtcat
    23401 ttgccttgat aaaatatcct caatctcacc gctagctatc tcatcaggaa gattttcctc
    23461 taaaacccgg taataggctt ggttaacctc ttcagacagt tgcgataggt cataggaggt
    23521 aatctgccct gtggccttta gctgctcata cagcgtctga agggctggtg tatcaaaata
    23581 aaaatccggc cgatgacgaa attcattgag caaatagtcg tgatgaagca ggcgatgcag
    23641 gaggtgactt tctgttttag ccaaggctgt catgcttttg ttaatcggta aggtcaccag
    23701 agatgccttt ggttgactag cctgtccttg ttgtaagctt tgcctatctt gtagccttaa
    23761 agcatttacc gattgctcca cctgaaaata atcaaaatcc ggcagcaaat cagccacctt
    23821 attaatatac gaattttgtg cggtgattga gggtgcttga gcaataatct gtgatatatg
    23881 ctccacataa gcaatctgcg attgcaggtt atccatattt tcaggcttca ggtgatcaat
    23941 caaaaactca acactgctaa tgcgcgagtg ctggagcaat tctgctagag cctctggtga
    24001 atgctgctga acaaattcat cgggatccat tctatttggt attttcacga tctccacttg
    24061 aaaatctgcc agcagctcaa gagacttggc aatagcattt tgcccggcgt cgtcaccatc
    24121 ataagtcaat acaacctttt gtgtcagctg cttgaggtgc ctaacatgct ctggcgtcaa
    24181 ggctgtcccc atagaggcaa cagtattacc atagcctgcc cggtaggctg caataacgtc
    24241 cataaagcct tccatcaaaa agacctcatg agtcttagcg attatcggct tggccttatc
    24301 aaggtggtaa agctcatagg acttgttaaa taggaccgta gcccttgaat ttttatactt
    24361 ggcctgctgc ttttctatat cctctcttgc ccagatacgt cctgaaaaag caatcatatt
    24421 gcccttatca tcacataagg gaaacatgat tcgatgacga aaggcatcat aaatagcatt
    24481 tgattgttca gaaacatgaa acaagcctga ggctgttaat tgcgcctcag tatacttttt
    24541 tgacaaggct tgataaaggt agtccatctc gttaggcgcc aagccaatcc gaaaatactc
    24601 tattagctga tcatcaagcc ctctttgata aagatactcc ttggctcttt ggccaatctt
    24661 tgtcgtcatc aaaaccgcat ggtaaaactt agcagcatct tcatgaagat caattaaagc
    24721 ctgatgaggg tgctgctttt gactcaaact agtctgactt ggagcaacag taactgccat
    24781 accagcctta tcagccacaa tctgaacact ttctaaaaaa ggaacctgcc gatattcctc
    24841 aataaactta aaaacatccc ccgacttacc gcagccaaag cagtgaaaga actgtctatc
    24901 ttcgatgaca ttaaaagagg gtgttttttc tttatgaaag ggacacaatc caaggtagtg
    24961 ccgaccagcc cgcgatagat ggacaacttc tccaataaca tcaacaatat tgacattatg
    25021 cttgatctga gaaatcatct ctttgtcaat agccaaaccg tcacctcccc acaaaaagcc
    25081 cattgtaaat ttacatttca ttataccatt gaaaatgagc tttgtaaatt gtaaaagcac
    25141 aatccttcat catctaaagc ccgctacatc aagcaataag ctatgctaaa gtattgacgt
    25201 ctcttatgat cactagcttg actagcagta cagcattaag tagctcatca gtccttgata
    25261 agctcttcta ttagcctttt tgacctattt gtgctatgat aagattatct gaaaaaaggg
    25321 gagtcaatca tgctcaaaga attaaaagca tttttattta gagggaatat tatcgaccta
    25381 gcagttgcgg tgattgttgg gagcgccttt agcgctattg tcacatcatt tgtcaacgac
    25441 attatcacac cgctgatcct aaacccagcc ttgaaagctg caaatgtgga aaacattgct
    25501 cagctcgcct ggaatggcat caaatatggc agctttctca gtgctattat caacttttta
    25561 attgttggta ccagcctttt ctttgtggtt aaggtcgctc aaaaagcaat gcctaaaaag
    25621 ggagaggaag agcccgctaa gcccaaaaca ccaactcagg aagaattatt acttgacata
    25681 cgtgatttgt tagccaaaaa ataactcaaa gctcttacag cagctggacc tgtccggctg
    25741 ctttttgata tacaagcaca gagcacttag cgatcaaaag ataatagaac cggctctatt
    25801 tgctgtttta gcatatcatt gctattttta tcagcagcaa gctaaggtaa aaaaagacaa
    25861 actagtatcc tcatactggt ttgccttcaa actaaggcag cctacaaagg gccgcctttt
    25921 ttatgatgat tagaattttt tacgtttgcg agctgcttct gatttgcgtt tacgctttac
    25981 agaaggtttt tcgtagaatt cacgcttgcg tgattcttga agagtaccag ctttagtaac
    26041 agaacgtttg aaacgacgaa gagcatcatc aagcgattca ttcttacgta ctactgtttt
    26101 tgacatatgt ttcacctcct caagatattg taacattttc acgttctagc ttatcttaca
    26161 tgatttttcg gaaaaagtca atgatctttt cttgattttg aggtcattct taaaaaaata
    26221 ccttaaaatt tgctgctgca ttaggcatca cttggcaagg ctattctact gcatttcctg
    26281 ttaataatgc tgcttcttga ataaaggcct tgtatttgcc atccttgttt aattgcttga
    26341 tcaccttatt aatggtttgc cttaggtcat cactcccctt tggcatagct acagccttag
    26401 catctccatc acttgcctgc aatttaaatg gtgctaaagc caggtcttta tgttgagcta
    26461 aaaagcctgc agctactggt gcttccaaat caacagcctg cacctgccca gatttcaact
    26521 cattaatagc ctcacccatc acagttagag aaacacagtt ggctttatta agctgctcct
    26581 tgactaggcc ctcctcgatg ctgccttttt gaacagccac ctttttgcca actaagctat
    26641 ccttattagc ataatgcttg gcatctgacg ctttcaccaa aatagcattt tcagtttcat
    26701 agtaagcctc agaaaaatca tacactttgg cacgctcttt ggtgtaggac aaaccagaaa
    26761 tcgctatatc caccttacca gtttgcagac tggataagac attatcaaaa ttcatagcag
    26821 agagttcaag cttaacccct agttcatcag caatggcctg tgccagctca atgtctgctc
    26881 cgacaatagt atccttgccg tcaaccaagg ccttaaattc aaaaggagca tagtcagggc
    26941 taacagcaac caccagcttt cccttttcct ggatcctgtc ttgaaggctc gtcttgttag
    27001 cttggccaca agctgccaaa gcaaaaacag ataccatagc aagtgctcca actaataatc
    27061 gcttcatgtt catattataa ttattccttt tcttgttgat gaatcttatt atattgcatt
    27121 attattcaat ggtcaagttt ttattgaata tttttcaagc actgcgatag tctgcttaat
    27181 cctgcctgta gaacctgcgg ctgacagcaa tagccgattc tcacatgatt tgcttgatta
    27241 aagcgatttc ccggaacgac caaggtaccg taatcctcca gcagcctcaa agcaaaggct
    27301 tccatgtcct catctatatc tagcctaaca aaggccgttg agacctcatt cggtctatgg
    27361 taggaggccc tggcttcacc tgttatccag tcctctaaga tagcaaggtt agtcctgata
    27421 atggcttgat tgcgctgcaa tagcttgtca gcatgcttca aggctagcga agccaccata
    27481 tcatcaaaaa cacctgcaca gatcattgtg taatctcgat ataacctaag ctgatcacag
    27541 atggtctcag aagcggctac ccagccaact cgaatgcccg gaatcgaaaa ggtttttgac
    27601 atgctattaa cagtaatccc cttatcatac aaatctgcca ccgctaaaag atgatcagag
    27661 gtaaaggaat gataaacctc atcacttagc aggtaaatat catgctctct agcaatattg
    27721 atgagctcct ctaaataagg cttggtcata taggcacctg ttgggttgtt ggcattgttg
    27781 atcatgatca tttttgtgtt gggacgaatc atggcaccta gctcattaag gtctggcagc
    27841 caagcctgct cctctctgat ctgccaataa tcaacctcca ctccaagaga agctggaata
    27901 tcatatagct gctgatagct aggatagtga gcaatcacat gatcacctgc ttcaagcagt
    27961 gcataaataa ccaaaaaatt ggcacctgtt gccccattgg tttgcaagat atttctagct
    28021 ttctgctgct gataaagccc tgccactgcc tgcttaaagt caggagagcc ttctatccag
    28081 ccatagtcta atggcttttg atgcagctgc tggtaaaagg cttgaggctg ctcctgtgtt
    28141 aagtcaaaga gctcctcaag cgttaatgaa gcaatagatg agccagcaat atcgtataca
    28201 gcacgttttt catgctgatt tagccactct tctacaccaa ataccggtag tttcataaga
    28261 tcaccttatt tcttgcgtaa tatttattac aatatcgcat aaaaatacaa ttgtcaaatc
    28321 aaaaactatc ctttttttga taagaatcat gtcctatcta acagttagtc ctgattggtc
    28381 tcgcatgaaa ggctactaaa tagagcaaaa atcacataaa aagactccca acccaccaat
    28441 cagcgggatt aggagcctga tagctcgtat caattcattg atttcagatc agagtgacta
    28501 tcatcactct actatgagcc aatgactagg ctaggcggac aacttctagc tgtgatccac
    28561 ccattaatac caagtatttt tcgatccttg caatcccgta ggattggctc agagcctcgg
    28621 catataggtc catttgctgc tgatagcgct gcttcagctc agctgactgc tgatagcgat
    28681 ctgtcttata gtcaaaaaga acaatacgat cctcaaaaag caggtagcca tcaataatac
    28741 cacgcactac gtactgctcc tgacttaggc tgtctttttt cagcatcgca aaaggagcct
    28801 cgcggtgtag gcgctggtga tgctcttgca ggagctgccc caattcagtt gtcgcaaaaa
    28861 aagaggttac cttttcaatg tcaagccttg ccttgacctc tgcgtcagct gagacaagct
    28921 gtaaggtctg ttcaatatca ccagcagtaa cctgatcaga cattggaata cgctgcatga
    28981 gctcatgcag gcttgagccg acctggctag gctcaacagc ctttttctta gaaaaatcag
    29041 gaagctcaaa ggtcttgggc ctatgataag gctgatctat gatatcaaca ccatcagtat
    29101 ccattagagg ctcataaagg gttttaagct gactgggggt tctcaccgtc ggcagctcaa
    29161 tggccgcctg atagcttgca ttgagctctg acaccttatc cagcatgtct aaggcacgcg
    29221 caatgtcctc tgtttgacgg ttatccttga gatcatctgc ttgcagcagc cctgagggcc
    29281 ttagctgacc aacagcttct ggtgttaagt cactgtcatc aacaaatcgc acatcaataa
    29341 acaagtcctc cttgctaaat gttgctgcta tcgctagtag ccagtcttga aagctcagca
    29401 atctttctcg actagctaag gctaagcgtc cttcggagct attgtcggct gttttttcct
    29461 gtaccttttc cttgctagcc ttaccaatga ggtatacctt tttttctgct cgcgtcatgg
    29521 ccacatacaa gagacgcatt tgctctgata aggtcgccaa gcgtagctgc tgcttattga
    29581 gctggtaagg aagagtttcc atcgtaacct tgagcgacgc caatttttct tctcttagaa
    29641 gctcctttac attggcgaca tatttgatac cgattccctc atctctattt agaatgattg
    29701 gcgcctgtag gtcagccatc gcaaagcgct tgtcgcaatt caaaatgaac acgtaatgaa
    29761 attcaagtcc ctttgattta tgaattgtca tgaggttaac agcatgctta ggcctttcga
    29821 cctcaacatc tgccaaatca ttttgcgtct ccagcacctt atcaatcatg ccaataaagc
    29881 gtgagagtcc cttgtagcct gattgctcaa attggtcagc ccgtatagca agggcgtaaa
    29941 ggtttgcctg agcctgctct gcctttggct ggcttgctac aaagtcaaag taaaagcgat
    30001 cgttaaaaat cttccaaatc agctcataaa gcgaatgaag ctttgcaaat tgacgccagt
    30061 ctctcaaggt cccatcaaaa tcagccagct ttgtcatcag ctcctgaccg atcagctctg
    30121 ggtgctcgcc ttgtcctctc aagctattgc taagcttgtc atagaaggct tgaggctgct
    30181 tttgtgagct gccttgcagt gagattcttg ccagctgatc ctcatcaaag gaaaacattg
    30241 gcgagcgcat taaggccact agggcataat cattcaaagg attgttgatg cttcttagcg
    30301 tatccagcat gaccatcacc tcaactgatt tgaggtaatt ttcttggcca ccatcagcaa
    30361 cgagaggaat gccatactga ttaaagacct gaaaaatagt gtcatttcgt gtgcgtgacg
    30421 aaacaagcag ggtaatatct tcaaaagcaa ccttctcctc gttatagagc ctgatgattt
    30481 ccttagccac taagatgacc tcacctgcgg agataccatc gttagctaag gcttcctcgg
    30541 tgccttcttg aacttgatcg gtgtcataga gcagcaattg ggctcgattg ttaggatatg
    30601 gctgtctttg tccctcactg cctgctacca gctggtgctt gtcatcatag gtaatctctc
    30661 ctaaagactc gtccataagg cggctaaaga cagcgttggt gacatttagg acctctgact
    30721 gactgcggaa attttccttt agtaaaatca gcttgccatg ctcgggattg ctttgataat
    30781 ccttaaactt ttgattgaag atttgaggat ctgcttgcct aaagcgatag atggattgct
    30841 tgatatcccc aaccataaaa cgattatggc cattagacag cagctctaat aggcgctcct
    30901 gcatgtgatt gttatcttgg tattcatcaa ccatgacctc atgataatga ccttggtaag
    30961 cttggcgaat atctggagcc tgttgtaaaa tctcaatggc aaaatgagct atatctgaaa
    31021 attcaaaggc attttcttgc atttttgcag ccaaataagc ctctgaaaag ctgatcacaa
    31081 aggcttgcag cacctccaaa agtggtaagc tctcctgttg ataagcaagg atagtctcca
    31141 agtgcctaaa tcttaccagc tgctcctgta gcgatttgaa aatagggtat ttgtgaccgg
    31201 ctacagttat atcagctcct gaaggaagta aagctgttag ctcctgtgct agctgaccta
    31261 gtcgcgcttt accgtaaagg ctgtcaaaat gcaaagccca ctcatataag ctgtcaatca
    31321 ttttgaggtg cttagtgtat ttggcagtta gcttgccagc cttggttgtt tgagcgtaac
    31381 cctccatgtc tgtgaggtct cgcagctgat cagcagtgtc ctgcatacag gctaagagag
    31441 catctacagc ttggtctgga atatctgtaa agctggtata ggtcttagac cctcgtaaaa
    31501 agacctctgc caaccaactg ctaggattgg cagttgattg actgaaggca taaatgctat
    31561 caacaatctc tctaaaggct gagctatcct tacgacgtcc agaaaaattc tgcaccagct
    31621 gtataaaggc tttattgtca gtctgcgaca tatagtcttc aaaaacctga cgaaagacct
    31681 cgcgctttaa aatgtcctgc tctgccttat cctgtatgat acgaaaatgc ggtgaaatcc
    31741 ctaaaacata accatgctgg tgaaccaatt tctgagcaaa ggcatccatc gtaccaatat
    31801 cagcctgtga taaagcctgc aattggtcat taaggtaggc cttgagctga taatcctgag
    31861 tctctgctat agctgtgtgc agcttttttt caattctctc tattagctca gtagctgctt
    31921 ttacggtaaa ggtcgaaata aataagcaat caaccggaat acctcttaga atcttatcca
    31981 aaatgcgctc aaccataaca aaggtcttac ctgagccagc agatgctgat actaagatat
    32041 tttgtccact gctataaata gcctcaatct gctgcgctgt ccgcttgtgc gtcttatctg
    32101 ataaggcctc ctcctgctgc aaacgagcaa tagcctctgg cgttagaaag ccttcatcaa
    32161 tcctcatgct ttatctcctc attcattcgt gtcaagaaag cctgtctcct ttcttttgtc
    32221 ggtaggacga ctaggcgtct cgcgtaccct agatctaaat ccgcctcaaa gcgcgtgatg
    32281 gccttgagct ggtcaccctg aacagacttg ccgtctgcgg tataagggtt tattaggaaa
    32341 tgccctgttt taatctgctt caccgcagac aaatatagct gctcattata agccagcagg
    32401 gtttctagct catcagtctc ataaagtgtg ttgttaaggt gatagctgcc attagccaga
    32461 tattccttgg cttgggctaa aaaaatgccc ttataggtta actccttgta agccgcagct
    32521 actagctgat catcaagtgc cttaaagtca gacagactta gccttggctc ttgcatgtgc
    32581 aggtacatgg cgccaaacag gccctgcccc ttattcttta gggcagcaag ataggtcaca
    32641 agctgaggac tcaagccatt gtaaaaggca acaatgtcaa atacccttgc actggatttg
    32701 tagtccacaa tgcccagcct accatcagct agctggtcaa tacggtcaat aacccctcga
    32761 ataagcactt gctgacccag cgctagctca aaggcctcct cttgcttggt tatctgcagg
    32821 ccttgattaa ggtctaagac agaggctgtt gagtaagcaa tcccctttag gacctctaag
    32881 ctatatcgcc cttcagcatc agcctgataa acctgctgaa aagcgctttg ctgattaact
    32941 gctgcaatag ctgcgcctag cttttggtca aaggcagcat tagacctatc cttggttacc
    33001 aactcaaaaa tacggtgcag gtattgacca tgaatgcgag catctgggtg aatagactct
    33061 ggctcttgca gccctaggac atatttcaag aaatacttgt attgattgtt ataaaataca
    33121 gtcaaggccg atgaagacag attcaagggc tgctgacttg aaaagcgggt ctcaataacc
    33181 tcaggtgcta ctggcttagt agtcaaatga tgctcaaaag ctggaagact tagctgctca
    33241 tcggctagcc tacgtttcaa ataacgaagg gcaaccgtcc aaaagtttct gtcctcactg
    33301 gtcatgtcat ctgcaattcc ctgccgatta atagccacca agcgagacaa gagagcctta
    33361 taattgccaa tatctgccgc tgagtgtgac aaacggttct ttcctttttc aatgactgga
    33421 acaccaaggg caattagctc cttcaggtaa ggagagacat catctgagct attcgttaag
    33481 cttgtaggca ggcttaacac cagctcctgc gtcgctgcat taaacaggga aagtgctgtt
    33541 tggtgatttt tcttgatatt ttcaaagctc ggcacatcaa ggcgctggta agaggcagtc
    33601 tgctcattga tgcttgccct ttcctgatca gagatcaggc tggtgttttt tgtctgctta
    33661 ggaaaatggg agcgactcag gccaatcgca aacacaaagg gcttggaatg cggctccacc
    33721 agatcatagg atttgataga cacaacatct aaggtcgcag gcactgtccg ataatgtgct
    33781 gtctgcatgc ccatcttgat cagagctaga cagtctgcaa gggtcatttt ttcctgacca
    33841 aacacctgat aaaaggtctc taaaatgcct gtgaaggctt tccaaacctc ctcgtccttt
    33901 tccctatcag tctcccttct actgcctgct agtgcctcaa aattatcagc cagctgaatg
    33961 gtcttaaaaa aggtcattag cttatcaagt agggaagccc ctagctgctt ttgactctta
    34021 aagagctgct ggagaggagt caccacagca agtcgcagct gattcaaaag aggcaaagga
    34081 tactgacgtg aggaatttag ggtaaagggt cttgaaaatt tggtgaagcc ttgaatatca
    34141 gcaaagacca agtattgctc aagctgatcc agctctccct cttgaaagcg cccaaagagt
    34201 cctgatttta gtaagttgac aatatcctca cgtcgccaat tgtatctgcg gcctctttct
    34261 aaggattcga caaattgaac caaggggtga gcagacatcg gctcttgctt gccgatataa
    34321 taagggatct caaatttctc aaaaatagga ccaatttgca gctgataaga cgccacatca
    34381 cctaaaagga caagcatatc cttatagcga taaccctgat agagcttctc acgaatagcc
    34441 tttgcaacat gctcaagctc ctctttttga ttgagcgctt gccagatcac aaccttgctc
    34501 ttgtccttgg cactgagctg ccaatcaagc tttgaatagt catgattggc ttcaagaagc
    34561 tgtgttaggc gagaaaatga cacatcaaag accttttctg acgttgtgta gatcggcttg
    34621 gtttgaaatt gctgtgccag ctgttggata aacgcaaggc tcgcctcgta gagatttccc
    34681 ttggtaaagg ctagtcgata agccttttga ctgatatagg ctccaataac gatttcttca
    34741 caggcttcgt ttaagagcgc tagcagctgc tcctcctcag ctgaaaagcg ggtaaagcca
    34801 tcaatcacta atacggtctg ccttagctcg tcatctaggc tcttgctttt gatagcctca
    34861 gcaagctgag ccagcctact tgactggtcg taatctcctt gtgcaatcag ctgctcagcc
    34921 ttggtcataa tcgtgatcag gtcctcttgc ttttctggtc tatcaagcgt cgttaagtca
    34981 aaggctgtca gattagctgc ttgcaattcc ttatatagct caactaactg ggcaataaag
    35041 gcctgatctg tccgtagccg gtgaaaaacc tttagctcat cttcttgcag ctgcatgagc
    35101 acacgataaa aaatcatggc taagccatta tcatctaacg cttgtcgatt agctgcctta
    35161 gctaaggtaa aataacgcgc catctgctca aagcgggtca ccgtaatagc aaaggaaccc
    35221 tgctctggca ataaggctag gacagaacgt tccttttcaa aggatagaga gttaggagca
    35281 atataaaaga cacgatagcc cttatcagca taagctcttg cctctttgac taaaatctct
    35341 gtcatggaat agctaatctc tgtgtatagt aatttcataa aactcctttt atttggacct
    35401 gatacaacgt ctatgcctcc attataacaa atcagccttg cttttcccat tgttaatgat
    35461 ctttcaaacg ccacaagaag cgctcacagc atgaaaaaag cctaccattt cacatctgct
    35521 gctttgcgca agaaatgata aggctttgtc ttgtataggc tcaaaaaaca gactaagagc
    35581 tcctagttaa gctgccctgt gcttgtctct tgtgatctgt ccccaggcat tctttttacg
    35641 ctgataacca ataaagctgc tcaccttgat aagggttaat accgtatgaa gaacaaggca
    35701 ttggtagatg gcagcataga ttacccaagc catatcaaaa agagtaatgc tactattgtt
    35761 ttgcaaataa accctattta aaaacgatgt caacgcaata agcacacaat agcaaatata
    35821 gagcagcatc agtgacacaa aaaaggttgt gtttaattga tggcatagca aagacagcac
    35881 aatgataata acaccaaatg cctcaataaa aggagataaa agctcaaaca aaagatacag
    35941 cacataggaa atgagtaccg tcgctttaaa ccgacagctt acaaaaaact ggagatactt
    36001 tttcaagcat tgatacagtc ctaaaaacca acgacgcctt tgccgacaca aatccttcaa
    36061 gcgactgggc gcttggctcc agcaaatagc gtctgtttca tagccaatac gataaggaat
    36121 cttgttgtta tggcagaaaa aatgtaattt catcaccagc tccatatctt ctcccagagt
    36181 cccagtgtca taaccatcaa cagcaatcgc aagctctttt ttaaacagtc caaacgctcc
    36241 tgatatgatt aaattcccag cagcctggtc taataaaaca cgagctccaa aaaaggcaca
    36301 atcatactca attgcctgcg cacacgaaat aagctgacgc ggcaaatggt agtctacgat
    36361 cctcccagct gccaatgcta ctccctgcga aaccttgacc atgcccccaa cagcaatgac
    36421 agacggatcc tttgcagcag tctttgcaat acgcttaagc gaatcctcct gtagcatcga
    36481 atcagcgtcc atgcacaata aataatcgta ttgagcagcg ttaatcccaa gattgaggct
    36541 atctcctttg ccgccatttg ccttttcaag cagggtcagc ttgatatgct tgagctgctt
    36601 ttggcttaca gcctttagag ggcgtgttgg gatccgctga ttaatcgaac aagtcaccgc
    36661 ttctaaatga aactgctcct tcaagagctt ggcggtatga tctgttgacc catcatcaat
    36721 gacaataatc tcatagcagt cataatcaag catcagcaag gactccactg tttcgataat
    36781 ggttagctct tcattatagg ccggaaccaa aatagacact ggcggtaaag aaacatcacc
    36841 accaacaggc gcttgctgtc gcctttcata aaggtgaata gtcccaacaa ttaaggatag
    36901 cagtaaaaag ctcgcatagg caatcaaaaa cgctaaaaaa agatattggg agtatttcaa
    36961 tactaaaaac agtagctgca ctatcattct cctttaacat gcaatcactt gtgcttacca
    37021 ttcgccttac aaaagcgtct caaggtctgc ttcatcaaat acccgatatt aaaggcaagg
    37081 atcgctaagc aaacgattat ataaaaaaac aacaggtaat aaatcatctt atcttctcct
    37141 cttttcctgc cagacagcct gcacctgctg ataggaggtc tttaaaactt ctcttaccct
    37201 tggacgctcc cagctcaaca gtggatactc taccattgca atgacctttg attcctttag
    37261 cggtgcaaaa ccaatagcta ttgcttcaat ggctaattcc tcaacaccat agtgctcaaa
    37321 ataatcatcg tgtattttgt ttgaagctgg atcagaaaaa ttgagcagct gccagggaat
    37381 cctaagctca atcagacgct cgccaaaaga aatatcggtc tgcgaatcaa aatgagccga
    37441 gcctcgtttg ccattgccct gttttaattg gccggtaggg tagcgcttca gtcctctttt
    37501 tgcaatcgga acctgatcaa tggctgcaaa aataccatca tttctcacca ccatatcaac
    37561 catagtaaat cttggcgtat gcttgttagg gggaaagaca taaaagtcct ttccattaat
    37621 ctgcctaagg taattggcat cagtagcatg gtagcgctcc tgcaccaaga ggcgactgcc
    37681 tttgtggtca tcaacaacaa gggcaaaatc agcaaagcga tcaaaccgag cgctaaagcc
    37741 ttcaataacc ctgctgcctg ttttgggcgt aatgtctaag ggaatgagcc actgtctttg
    37801 taagggctgc ttttttgtcg attcaatagc aatatagagg tatttttcgt cctgatcaac
    37861 gaggagctgc tgcccatttt tcttgtaggt tagagctcta gaccactcat ctgctgcctt
    37921 ttgcccatca atagcatgcg tccttggagc atgctcaaag gttaagagac cataaccttg
    37981 agccttagac tgaacatcac cccaaagaaa gctttgatgt ttattggttg caaaggaggt
    38041 attccagctc ctagcagtcc aatcgtcctg ccagctatgg atcgttgcac cacagcagcc
    38101 agacgcaata aaggctgtgt aatctgccat caagcgctcg ccttgatcct tttctgtcaa
    38161 agggctggaa gtcgatatca tttggtccac acctctggct gtcgaatagc catagcccgt
    38221 cacaaccact gggacacgat gatagctcgt cagtagcttg acgtatccct gatataaggg
    38281 catgcgctta atatccccaa caagcctatc agtaagccct agacggtcaa atagcagata
    38341 atccctataa gccgagtgac aatccaagag cttataggaa gcaaaaagac cggccttaac
    38401 cttagcgctg ggcttaatat tttcaatcgt cagttgaaca tattttgctg cctgagaggc
    38461 aaagggatcc tgatagacaa agggatctga ttgaggcgta tttgaaaagc tcaccaagtg
    38521 ctgccagcca tatttgcggc tctcgtatga cgtgatttcc tccatgattt cagccagtat
    38581 agcctcaaac cgattggcct gaggtgtcgt tgcataatac cttcccttaa agcctacagg
    38641 cttggcgtga ttctgatgat tggtataggc tatcgtccca ctgtaccaat catcaccaac
    38701 aatatagccg agtagccatt tactcatatc ctgatcataa tgctgaagcc ctaaatccga
    38761 atgccagatc cgttttctcc catgaatcac atcaacacta gccctagctt cccttaacag
    38821 agtgcctaaa taagccttat ctaaggcgct gatagaagaa ttgtcatgat aagcatctat
    38881 tctaaagccc tgtaataggt acagaggatg acttgctctg tcattgtagc gtctcaaagc
    38941 atggtaaaaa gtgacgggca taataaccct taccctgatc gtatttgcac ccatagctgc
    39001 tatttgcttg aaccacctat agtaggtttt ctcatcaacg ctaaggtctc gtcgacgata
    39061 gcctgctatg gaactctcca catcaacacc cttgatgaga taaggagatc ccttttgatc
    39121 atatatgcgc ttgtccttgg tgtaaaagac tgtccgaata gctgactggt tagagaccgg
    39181 caggtacaag cgaccatcaa tatcacaaca ataatagctc aagccaatca cagacaagag
    39241 caaaccaaca aagattaaat atttcttcat cactacctac tccaataatg tattggtatt
    39301 tttagacggt gcactgtact gatagagcgt ctcaatatgc ttatccagcc atcgcccacg
    39361 acgtctaata aagtccttta gttgcttaac agaggcctca tagctactgt agttacgact
    39421 ggctggcaca aggtaattag tggcatcgct tcttgatggc actgtaaaca catagcccca
    39481 cttatgataa ttgcgctgaa tagccggacc taaaaaagca accgtagcat caatatactt
    39541 gatcaaataa tccgttgata aaacattctg tcggagctga tgataccttg tgaccaccag
    39601 cttaacaaag ctaggatcct ttagcagcat gcaaaaccaa ggagcatctg atagggtaaa
    39661 gtccgcctca tcataaggag cctcaatctg attatcaaag gcgttgttaa aatcccagac
    39721 caccagcttg agcttatcgc gcaaatcctt ataaagatag gttgaaaact tcccagcatc
    39781 aatatttcta aagaattcat tgataataaa atagtctgca aaggactctt ggtccagata
    39841 atcagtgtat tgctttaaat cataagaata taggagcttt tcgatatgac tgatatcctt
    39901 ttcaataaac tgcttttgct taggcgtcag acggtgcagg cttgggtatt taatgtctaa
    39961 agaggacaga cctgcttgat tcgtatagga tacgtaatga tcaagagcct gcttagcctt
    40021 gtgtcttcta tcccaaacaa ggatataagg cgttttatca gattttctat cacttttttc
    40081 gatgtttacc ctatgccgcc cctgctcaat actctccaca gccaaataca gaccacaata
    40141 ctgatgatcc accactaact cgcaatacct gacgttaggt gcataggtca tgatctcacc
    40201 ggcaatattg tagctaagat aatttcggac tagggtccga tctaaaaaag gaccatgcag
    40261 cacccactca gactccttgg acatgccagc cagcgagact gcctttggct tagctctttt
    40321 attgataaac cttagcttta aggatttctt gtcaaaatga cgtgacgaat tgcccctata
    40381 agcaatcaat gctgtcaagg acaagcgcgg agactcagac aggctgtgct ctctatctag
    40441 ctgatcacga agcgagaccg tcgttttaat ggttttttgc cgctttgtct ctccctcgta
    40501 ttccctttgc tctggaatct gctgatgatg agtgtcaatg ctaataatcg gcaaatgaga
    40561 gctaaactcc ccagtgcttc tggagctctt tttgaccgtc tgcaaatggt gatgaatacg
    40621 ctttgcagag gtcttaggaa aaccgatacc acaaatagca gctagcaaga gacacaccag
    40681 cacaatcaca taaatcgtct tttctttcat ttacgtcaac cagttatgtc atcgctttga
    40741 ctaacaatat taaaataatc aactcgcccc agctgataaa cagcctcagt taacggatta
    40801 gcctgctgat aggtgctgtc ataatccttt cttgacagct caaagatcat ctcaatatca
    40861 tcagacgtgg tgtttttcac gctctggatc gccttacccg aaaagtagtt aaacactaac
    40921 cgctccagct caatttccat ttgcttatca cagcgaacaa tcaacaacag tctattgtca
    40981 tttctgacag ctcccataag caacaaaagc ataaagatca cgctgctacc agttgcagcg
    41041 acagtataat caccaacacc acagcaaatc ccaaccacaa tcgtccaaaa aatatagact
    41101 gtatctctag agtctttgat tgctgtccga aaacgcacaa ccgacagcgc accgaccata
    41161 ccaagagaca aagcaacatt atttccgata actgtcatga cggttgctgt taagaccgtc
    41221 aaggtcatca acgaaacatt aaacttcttg ctataggcag tcccagtgtg ggtataggca
    41281 tatgacatat aaatcacaat acttaacaag gctgcagcaa caatatgcag caaaacatct
    41341 tgaaagctca aggtcccacg ctgttcaaag acatgtctta ataattgttt catcttaata
    41401 tctctcctaa aaacgataat gcttgctgat agctctcccc atgcaatact tgcttgcact
    41461 tagctcgcta ccattaacag actccaaaag ctttttgata taagacaaca aaaagccatt
    41521 atacttgacc tccaagatga ccaaataggg atctagcagg taattctgag gcagatgatc
    41581 tgaaaaaata tcagcattgg tctcagaccc gataatatga tgatcaaagg taatgcgaat
    41641 attgttttcc tttgccacaa atgccttgcg ctggtattcg atcactgttt ttggctgata
    41701 gagctgcatt gacatgcgac tatagcattc agcagcaaag cgatcaggat aagtcagcaa
    41761 tatagacttg tctcccttaa tcaacaattg agcgtctgct ctggtcaacc tcagagatcg
    41821 ctttttttga ttgctccctt gcttttgctt catctccaac ttagcaaatg agctctgact
    41881 accgtaattg cgcaggcgaa tttttcgcct aagctcaata ccgtcctctt tttcctgcca
    41941 gtcaacgtcc tccaaagaat caaaatacaa ggatcgaatc acatatccct cactagagct
    42001 atgagcatct agacgcaaga gcttggaaaa ttcatgcgat aagcgataat aatcctcaat
    42061 ggtaatcaaa tacttttttt cttgacgcaa tacctcattc acgccagtgt cctccttttt
    42121 cgtctgtaag caatgcctta acaccaagct gcctgtaaca gcagccaaca aacctgtctc
    42181 ataaataagt cagggcaaat aaggtgattg ttggctctac aagagtcaat cacctgccaa
    42241 aatagtaaat cctgccatct gttgaaataa tataaaccag ctgatcgtct tgattgcaag
    42301 acaggcgctt ttgtgactga tctagctgtc tgctgctaat atcagttgca ttagcctcct
    42361 tgagcatggc ctgcttgagc tgttgctgga tttttctggc ttgcagctca gaaatctcaa
    42421 agctgccatt aaccttttga gccttgtgct tgtagaccag tgccacatgg tctttagctg
    42481 ttgtcctagc agtcgacagg agcccttctt tgttgagctg agtatgctct cctacatcaa
    42541 tggcaacata gtcatagggt gcccgtatcc ggtgcgctgt tagtattgag gacaaaatcc
    42601 ctgtcacaag gcagatgctt atcgtagcca ctatcatctg ctgccgctgc ttacgaatga
    42661 accttgaaaa agcacagacc tccgcctgat attcctgaag ctcttcttca accttactgt
    42721 aatcctgtct aagatcagcc aagtcagtct gacagtcctt gcagcttgtc agatgagcct
    42781 caacaaccgc tctactataa tcactcaacg tatcatctac atataatggc aacaaatcct
    42841 ggatcaactc acaatcatac ttcatagcca tactcctctc gtaattgtct tttaatatgt
    42901 tttcttgccc taaagacaag aaccttggca gaggatactg tgatgccaat atccttagct
    42961 attttttcat aggaatctcc cgaataaatc ctcgccagaa agacagcctg cattttctct
    43021 ggaagattaa aaataatcgt tagtgtaatc tctaacagct cccttcttgc tatcttatca
    43081 agtggttcat catgcccttt agcatcaacg atttctaagc tttccatcga catattctca
    43141 tattttttct ttttaatttc tgtaaagaag gtgttctttg caatggtaaa taaccatgtt
    43201 ttgattgaac tatccccact aaatttagca atattacgat aagcctttag aaaagtctct
    43261 tgagtaatat catctgataa actattttga taacagcaca gcttatttac aaacct
//
LOCUS       DARYXW010000006        41275 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.006, whole genome shotgun sequence.
ACCESSION   DARYXW010000006 DARYXW010000000
VERSION     DARYXW010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41275)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41275)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41275
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.006"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            398..811
                     /locus_tag="TV191_000258"
     CDS             398..811
                     /locus_tag="TV191_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL1506810.1"
                     /translation="MLNKMKRLHYLMIFRLLTGQLPAISLMAVLLSKDIHRLSLGSLI
                     SFAIFAVSTAASNYYFSREIAIEQLKEQTRPNLLLTQILFIVVFMIIGIVSIYCGLSS
                     SEFYKQVIAVICSFISFVTMGLMIWGIRYAKAYRR"
     gene            1071..1652
                     /locus_tag="TV191_000259"
     CDS             1071..1652
                     /locus_tag="TV191_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HEL1506811.1"
                     /translation="MRRIRLATLADAKALLDIYRPYVEETAVTFEYTVPSLTEFERRL
                     SDIMVFYPCLVVEEEGGILGYAYASRFHARAAYAWSAEVTIYLAQEARGRGLGSALYH
                     RLEGYLKGMGILNCNACIASTAHATPYLTNSSQVFHEKLGYRLVGRFHQSGYKFNQWF
                     DMIWMEKLLGEHDVRPRPVMSFRDFLCQKHQSE"
     gene            2062..2388
                     /locus_tag="TV191_000260"
                     /pseudo
     CDS             2062..2388
                     /locus_tag="TV191_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419586.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin, lactococcin 972 family protein"
     gene            2457..4460
                     /locus_tag="TV191_000261"
     CDS             2457..4460
                     /locus_tag="TV191_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1506812.1"
                     /translation="MRWRATVICIFVLLLTCLSFGAVKEYGNDIKYPVQAAFSLVASN
                     KDVDKGHVLDRIEALAEQEHIQIYRPYLDHTGKEATYLFGTNGKKTVYSSNRKELLTN
                     DLSGMYYTTRSLPSSFETAMTERGLTYKGADLPWYLLPYYFLFTNLRSLAIWTLFFVF
                     ALLLFAVKLMYAKKSMILRSLGLFEHYSRKELLQDLLLMGASFAVSILLFILYQGSIS
                     NVFVKSFTLLILTNAVILLLLMLAVHALFFINIRSLKALAILKNKQATPLVLFVWLVG
                     ICLSSVIFGLSLHKSLETIGKSANDIQVLGKWDKAKDFAEITWLDTLSTHTDDNHQID
                     SDYFKEENQRYQHFLLSFSDNDVIYSALSSLNETNLQSAPDDFKKELKTNGVDPRIAS
                     KVRYVNQGFMLKNKDIFPNNDYGRPAADAVGVIYISKHMMGDADSILNIVNYEWFQYS
                     SLKANQLVVQEVPDGQKSFLFNHKQDQQDIFAQQEEVNTILVQLNFSFMTEPSLLTKF
                     GEMAQKSIYRQALIRDRLTQAGLTNFSSLTNVSNHLILERHKILSQLIGSVIALTVLA
                     IAQCFIIYEYIVSLMKQKAKKISVWFLMGQKSLVLIGRLLLPLALCLFLAIGMMGILT
                     GNRLMVLGIGLLYLGEIVCMSFFAYQAILKHRIQIIKGDFDIL"
     gene            4457..5065
                     /locus_tag="TV191_000262"
     CDS             4457..5065
                     /locus_tag="TV191_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1506813.1"
                     /translation="MIEIKQLSKHYGKKTIYDKLSLTFEANRSYALVGPSGSGKTTLL
                     NAIARLEKPDSGQILVNGQDIWSMKEQDYFKDYLGYVFQNYALIEEETVYDNLKMLAP
                     KSNIVEALHSVGLDSSFLSQNIYELSGGQAQRVAIARLLLKKACIILADEPTGALDKE
                     TGDEIIELLLSLVSPDTVLIFATHDPNVFSRVDDIIDICHLQ"
     gene            complement(5254..7980)
                     /locus_tag="TV191_000263"
     CDS             complement(5254..7980)
                     /locus_tag="TV191_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEL1506814.1"
                     /translation="MTPKKVHIISHSHWDREWYMAYEQHHMRLIQLIDDLLDLFKTDP
                     DFHSFHLDGQTIILDDYLQVKPGREAEIRQAIQAGKLRIGPFYILQDAFLTSSESNVR
                     NMLVGKEDCEQWGASVPLGYFPDTFGNMGQTPQLMRKAGLNAAAFGRGIRPTGFNNQV
                     DTSEKYSSQFSEMIWQGPDDSRILGLLFANWYSNGNEIPTEEKKARQFWDQKLADAER
                     FASTRHLLMMNGVDHQPVQLDVTKAIALANKLYPDYDFVHSCFEDYLADLSQELPEEL
                     SIVSGEMTSQETDGWYTLANTASARIYLKQANTRVSRQLENITEPLATMAFEVTGTYP
                     HDQLRYAWKTLMQNHPHDSICGCSVDSVHQEMMPRFDKAYEVGTYLAERSANQIAEAI
                     DTSMFPEDSCPFVLFNTCGHEKKTVSDLTLTWKIFPFGQRLPKAVYQEAKEYLETRQP
                     QFQVIDAAGRIIEEAEILGTDIAFDYALPERTFREAYFAIKVQLRLPLTLSAMSWQCL
                     ALKETDQPCQATDTDKMLFHQDRSCLENDFLKVIIAANGLLTIEDKLNGNRFDSCLQY
                     EDCGDIGNEYIFRQPDHDSPYLAHQGSCKLRVLTNTAYLAEIELTQTFDIPLATDDRL
                     KAEMEAVIDIRERQAKRSQEKAPFTVTTVIRMEKDSPRLQFQTSFNNQMTNHRLRVLF
                     PTHLKTDHHFADSIFETVKRPNHTNAQFWKNPTNPQHQEAFVSLFDGRTGVTVGNYGL
                     NEYEILPDTNTIAITLLRSVGELGDWGYFPTPDAQCLGQQTVSFSFESINATTRFASY
                     WRAQEAQVPVTMAQTKRHSGQLPAQYAYIKGATDHVALTAFKRRLSDNALITRSYNVS
                     NDKACALTLAIPDHTARVTSLLEEDQHEPLPAELGKGEILTLAWKKSESAHL"
     gene            complement(7995..9281)
                     /locus_tag="TV191_000264"
     CDS             complement(7995..9281)
                     /locus_tag="TV191_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEL1506815.1"
                     /translation="MTRPIPSSVLRFMDTIEELCGEEHRSWAINFKASFANTLETTLK
                     IDEDGTSFLLTGDIPAMWLRDSTAQLKPYLFLAKTDAGMRQIIAGLVKRQFRYICIDP
                     YANAFNEEENSKGHQADHTQMGPWIWERKYEIDSLCYPIQLAYLLYRETDCTEHFNED
                     FHRGIKLILDVWSTEQDHTASPYSFERDTWRKEDTLTHNGKGAPVAYTGMTWSGFRPS
                     DDACQYGYLVPSNMFAAVVLSYLEGLYTDLFKDQTIARRAHALRLAIQKGIEEHALVT
                     NSQGEIIYAYEVDGLGHYTIMDDANIPSLLAAPYLGFCAKDDPIYLATRQTILSPENP
                     YYYQGSAASGIGSSHTPPNYIWHIALALQGLTALDQKDKADILDLLVATDAGTHLMHE
                     GFDVNDPSHYTREWFSWANMMFCELLLDYLGFTISP"
     gene            9414..10472
                     /locus_tag="TV191_000265"
     CDS             9414..10472
                     /locus_tag="TV191_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1506816.1"
                     /translation="MTELLYKKIYHFIKEQIDSGQLQAGDRLPTEKALSEQFSVSRIT
                     SKRALVELEQEGLITRSRGKGSFVTDGPPPSTQPNKDILLILPFASDYELGDYAKGIM
                     TVVADKGYRLMVQLTSTVSLEELADYAGVIYYPEDVNHSIELLFYCAQRGLALVLLDK
                     ALDLFDFPAVVADNKGGAYELTKHLIDQDCRRIMFVATASFGEVSSVRDRYLGYLAAM
                     AETELEANYFVKLKSESNAAYLERLVDELTAATAEKTGLVVENDWLAIQLIQKILQVG
                     LSIPDQVAVVGFDNSQASQLISPQLTTAAQDFYQMGQQAAQLLIERLTRPDQQTASCQ
                     LPVKVFIRESSQKSLEML"
     gene            10487..12181
                     /locus_tag="TV191_000266"
     CDS             10487..12181
                     /locus_tag="TV191_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylglucosaminidase domain-containing
                     protein"
                     /protein_id="HEL1506817.1"
                     /translation="MSIYQALKDYQEVITRGDYLVFDAPVSCRFVGRFFRFENQTAMK
                     PSLTASVYVNWVEEGAADLTLKHVFNRTLARDAFTLTISEDKELVIESQNLRGFRYAQ
                     EALEKVMTVKEGRLYLPIVSVRHSPSFAMRGVIEGFYGTPWTREERLDCLSFIADKGM
                     NTYMYAPKNDDYQRSHWREPYPEDWVAHFRDLIQLAKERQVDFWYMISPGLDFDYTKE
                     EDYQLLYQKLQQLLDLGVCHFGLLLDDIDYQIVAAVERRFKKTAYAQAHLATAVYQFL
                     QRQHAAPDLVVCPTEYDNHHDSLYLAELSEAIPAEVAFFWTGPSTLASQISQADIETI
                     AAIYRRPIIIWDNIPVNDYQDDSKRLFLTPFANRSPFLCQPDYQVRGIVSNPMISWEL
                     SKPTLIDMSRYLWDAKRYQPSYSWLEALRDYTGDKAMALALLRFAWHNGNRHLHRDLP
                     FEVEEALMRKDIASLSGWVAELVELVDKLKELDIPAFQQAIAPWFDRAKADQSFWRVI
                     LEQAPDLEQQYAELQEQRHRIGSNIPSRFYQLHYLQENSMLGNQAQVAEARAEDYT"
     gene            12208..13599
                     /locus_tag="TV191_000267"
     CDS             12208..13599
                     /locus_tag="TV191_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEL1506818.1"
                     /translation="MLEFPEGFWWGSATSGPQSEGCFQKPHRNLFDYWYEQNPELFYD
                     YVGPDTASDFFHQYDQDLALLASLGHNSYRTSIQWTRLIDDFETATINPDGLAYYNRV
                     IDACLAHGMRPVINLHHFDLPIALYQKYGGWESKHVVDLFVAFARVCFEQFGDRVKDW
                     FVHNEPMVVVEGSYLLQFHYPAIVDGKKAVQVAYNLALATAKVICTYQEQAAELSNGS
                     VGTILNLTPIYPATDSEADLAAAHVAELWHNDLFMSAAVYGSFPKELVAILQRDGVLW
                     QSTPEELDLMAAYTVDYVGINFYRPKRVKAPEVIPVISPSWSPEWYYDAYLMPQRRMN
                     VDKGWEIYPEAVYDIALKMRDQYRNIPWFLSENGVGISGEDRYRDESGQIQDDYRIQF
                     LKEHLTYLHKGIQAGSNCFGYHVWTPINCWSWLNAYKNRYGLVENNHRTQRRRVKKSG
                     YWFKEVAEANGIS"
     gene            13586..13723
                     /locus_tag="TV191_000268"
     CDS             13586..13723
                     /locus_tag="TV191_000268"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1506819.1"
                     /translation="MELAKKRRKTQKPAQSPLKLGLEKLREILQEQLVALAVLPARVM
                     G"
     gene            complement(13919..16093)
                     /locus_tag="TV191_000269"
     CDS             complement(13919..16093)
                     /locus_tag="TV191_000269"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEL1506820.1"
                     /translation="MDRLDFIDTRFGTTNHYHFSQGNCLPLTGVPFGMHYLSVETSQD
                     RGAWWFHPDDHSFSGIRLTHQPSPWVGDFATVTFLPVSGPLTKGDVFHNQTSYRPKEA
                     AFRPHLLEIFSQRHRILTRATAAAYSFHCDFSFDNGKAGLIIHNPGKSSWQVTADGKT
                     ILGCVQNITDCQDKDLAMFVYLQFSSPVLKKLIGEDLNSKSLDDCSKTSFTYLQFADD
                     LKHLELRAAASFISFDQAQLNWQRDFPRSFEKSLEYSRKEWLSYLSRIDIKDKDFDKV
                     KAYYQHFYRALLFPQRWYEITATGQAIHYNTTSQRPVAGKYYTNNGFWDTYKSVYPLL
                     SLIAPEIYADILEGLLSAYQDTNYLPKWLSPDERGLMPGTLVDAVIADGAVKGIRKDL
                     MPELLEAMLATANTDSQGTGYGRKGNQDYQELGYLPNSYQESVNQTQDYAYSDFCIGQ
                     VAALLGKTALSDQYHTRSLNYRHLVDTDTGYLKSKDRQGQWQCGFNPIHWGQDYTEGS
                     YYQNGFAFYHDILGYIRLIGGNAAIAKRLEELCNHEPVFDVHSYGFEIHEMSELAAQD
                     FGQIAISNQPSFHLPYLYHYIGQPQYSQLILKNLLSHAFTDTGYPGDEDNGSMSAWYL
                     LNSLGLYPVTPGTGQYLIGIPTVDQATLYLPNGNTIQISCRGNVPQYQFVKEVKLNQA
                     SYNKLYINHDDLIQGCQLDFQLGLVPPLKHYSAEDLPYSLTR"
     gene            complement(16081..16974)
                     /locus_tag="TV191_000270"
     CDS             complement(16081..16974)
                     /locus_tag="TV191_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEL1506821.1"
                     /translation="MTLLCIDIGGTSIKFAICHKGRLKKQSSRPTPQSLEDFYHMLDE
                     RLAYYRTEKLSGIAISSPGAVNKATGIIEGASALPYIHGFPIQQCLEERLGLPVSIEN
                     DANCAALAESALGAGQGTSSLAMLVLGTGVGGSLVINGRIHYGAHLFGGEFGFMVMNE
                     RYQTFSELGTVVNMAKRYSQIINDGKSYTGKEVLELADQGDPVALKERQVFLQSLAMG
                     VFNIQHAFDPEMILIGGGVSQADFLLPALEAELDKLYQIVSISDLRPQLAICHFKNEA
                     NLLGASIDFMQEHRKDEMWID"
     gene            17186..18136
                     /locus_tag="TV191_000271"
     CDS             17186..18136
                     /locus_tag="TV191_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004219264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1506822.1"
                     /translation="MTTKISSKKSFWKNVIKYRALLLMVLPGFVWFIFFFYIPVLANV
                     VAFKDFHYSAGGFMESLKESPWVGLDNFKYLFASKDAWLITRNTIAYNLIFLLFNVFF
                     AIAFAIIMSELRNKKAVKVYHTMSLLPYFLSWVVIEYFVSAFLNTDKGFINQLLIDSG
                     NSPIKWYSNPTWWPLILLFMSVWKGLGYNSIIYYASVKGISDTYYEAAMVDGASKWQQ
                     IRHITIPQLLPMMSILLIINIGSIFKSDFGLFYVIPKNSGPLYDVTSVLDTYVYNALT
                     ATGDISMASAASLYQSVVGTCILLITNAFVRRMDPDAALF"
     gene            18146..19072
                     /locus_tag="TV191_000272"
     CDS             18146..19072
                     /locus_tag="TV191_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEL1506823.1"
                     /translation="MEKKKTVKRVNVRTFDPKTNAVFNVLIALFAISCIIPFIFVMII
                     SFTDESYLINHGYSFFPAAWSTKAYHYIFQGAMSHRIIRSFAVSVFITVLGTFINTTM
                     TSTYAYAISRPYFPYRRFFTIYALITMLFAPGMVANYLVVSNLLQLKDTVWALILPMA
                     LGPFGILVMRTFFKKTVPDSIIESARMDGAGELMIFMKIVLPLAVPGIATISLFSALT
                     YWNDWFNALLYVQSESLYPMQYLLMKIQSNIQALAQNAGMSAQLSDSLASLPKESVRM
                     AIVVIATLPIALTYPFFQKYFVGGLTIGGVKE"
     gene            19156..20601
                     /locus_tag="TV191_000273"
     CDS             19156..20601
                     /locus_tag="TV191_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL1506824.1"
                     /translation="MKKWQTILCVTGAVLAAASLTACGSKSASKDGEVKLLMYQVGDK
                     PDNFDELMTIANKRIKEKTGATLDLQYIGWGDWDDKMRIIIASGENYDIAFANNYVVN
                     AQKGAFADLTKLMPKYAKKTYKNLDPAYIKGNTIDGKLYAFPVDANVYAQQMLSFNKE
                     LVDKYGLDISNINSYADAEKVLKQFHEKEPNTAAFAIGQVFSMSGDYDYPLTKNQPFA
                     VKIDEGKPTIINQYEDEPFKANLRLMHKWYKEGLIPTDAATNTEGYPLEGNTWFMREE
                     TQGPMDYGDTILTNAAGKDIVSRPLTKPLKTTSQAQMANFVVSNVSKNKEKAVEVLSL
                     LNSDPELLNGLVYGVEGKAWEKVGDKKIKLLDGYQPKMHMGAWNTGNNKILYTQESIT
                     DDMIAKRDQSIKDAKESPILGFTVDTKAIKTELSKISNVMNRYKASINTGTVDPDEAL
                     PKLLSDLKDAGWDKVQKEVQKQLDDFVTKNK"
     gene            20949..21554
                     /locus_tag="TV191_000274"
     CDS             20949..21554
                     /locus_tag="TV191_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HEL1506825.1"
                     /translation="MTGIEKACFLIWKMMQLTLIFHLLSLCGAVIFGVGPAWQTIVTL
                     FLETSQQEKHYSLKRAFQIWRRVFKEANLSFFFFGLLLLLLNTSLYLAIQFQSLLWFS
                     LSFIIMFVMVWLVMIVIYMTFYAVTYEIAFWENLKLSFISIFLNARQFLLTLVVLAGV
                     AWFTWQYKGLYLFLSFGALVLLLDMVTKPNRRMVDGVIDDK"
     gene            21544..23268
                     /locus_tag="TV191_000275"
     CDS             21544..23268
                     /locus_tag="TV191_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1506826.1"
                     /translation="MTSKSLKRFLMEHIKQGFLINRLMKIYSLFIVALFSLSAVGLST
                     YSIRNTYQMVDNQMQMRLDETLARLQSQNYITLRVLEQLIGRPEDYRNLYQYMILTPN
                     QYLTKVFEDWGEGKNTPLFSEQVRRLFDLYPDLDGLTLMLDDSTSYLYADRSIKTGRL
                     LFGKPQTLKGNYLVRSIRHPESGDVTGRLYLHFASPSTMLQPEQHKYLATFAFDYYGR
                     ELFHQGGAAFPELEAGLKKALKADQAIDLTALSKSYHIQYNRSGDLLAYVAVKRSYFM
                     EEAVRTMLLYGLGSLLLAWLLLQLLFRVFRNYIRQVSEITDTIEMVAAGDLSLRIDNS
                     HMELELYHISEAINQMLGNINAYILEIYVLEVEQRDAQMRALSSQINPHFLYNTLEYI
                     RMYALSCQQEELADVIYAFAALLRNNISQDKVTTLKEELAFCEKYIYLYQMRYPDSFA
                     YHVKLDPVVADVEIPKFIIQPLVENYFVHGIDYSRYDNALSIKALDEEDSILIQVLDN
                     GKGISPERLVAIEKGLEEPQSTGNSSIGLQNVYMRLFHKYRDRVTWSMSQAPTGGFRI
                     QIRIRKEA"
     gene            23268..24752
                     /locus_tag="TV191_000276"
     CDS             23268..24752
                     /locus_tag="TV191_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1506827.1"
                     /translation="MYKVLLVDDEYMILQGLKVIIDWQALGFEVVATARSAKEALAYL
                     DDCAVDVMISDVNMPGMTGLELIEAARDVLPHLQTLILSGYQEFSYVQRAMELETKGY
                     LLKPVDKKELVAKMLYFKEWLDEQRAASLRQAAYREGLINLWLADELSEKEFFQLTQE
                     QPEAELLGFTVLYVDCKTFSPALEAFFEASKQPFYLKKAEQKKVYLVILLGQSHQAKR
                     FTNTLQERFYNTINQIILGETVVDWENVYESYNQVRRSFFYNSEVSQVAAKTNAKIEL
                     PESRLQFFSFNKTLMIGDEPTIVSKLQAIFEEMTELSFSPEDVKHVSFLLFSDIYRQF
                     PILDRTTYLSMVKTIHDSQSIDQILSALKKVLELTSKSNQPQKRYSDLVSEAITCIQE
                     EYSQELTLKAVSDRLHINGVYLGQRFKNETECSFSQYLNQVRIQKAQQLLLYTNKSIN
                     EIAYETGYNTNHYFIKMFKKLNGLSPKEFRDRYKDNYQAIKGSY"
     gene            24766..28209
                     /locus_tag="TV191_000277"
     CDS             24766..28209
                     /locus_tag="TV191_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2 protein"
                     /protein_id="HEL1506828.1"
                     /translation="MSVETITGSTDQSHGDIYQLHWIDKVGRCHAFSKGWRFLMADLQ
                     LAQEPFFDDSDWQQIALPHDFSINQPYTVNGEAQSAYKLGGVGWYRKYFALDPKLADH
                     KVYVTFDGAYMETQVYLNGHLIGEHVNGYQAFSYDLSAFVIPGQENLLAVRVEHLVPS
                     SRWYSGSGLYREAFLTVLPKVHLDKDRLRLSLSQAALEADSQALEIELGLSQQVPLSG
                     YQLSLSLFEQLADIQQRQTVYESKPVALDLLEESGRLVMTIPLRHIKLWSPAQPQLYQ
                     LDMLLYHKGAVLDRLTLETGFRQLHFDAECGFFLNGKAFKLQGVCLHHDQGSLGACAY
                     EEAIARQLVLLKEMGANTVRVTHNPSARRLKDLANRLGLFLIEEAFDTWTYAKNGNSH
                     DFSSHFHKTVGHQNAARLKGVTTAETTWAQYSIQAMVLSGLHDPSVLMWSIGNELLEG
                     FSADVSHYPYVAKELCQWITELDQSRPITLGDNKLKDKHFHWAQETKALAEQVNQLQS
                     VQGVIGLNYAKARDYDRLHRDNPTWLLYGSETASAINSRGVYHLKGGASQDHELTSYD
                     QSTVDWGSLASEAWYDTITRDFVAGECVWTGFDYLGEPTPWNKIDSGAADQWPSPKQS
                     YFGILDTAGFAKDSYYFYQSQWSKDKTTLHILPSWQEKDLQLDDQGMVEVVVYSNAAS
                     VRILFDDGHGGQIDYGIKTLTRHETPAGHCYQLYEGDDAAELPHQNLYLTWKLPYRSG
                     SLRAIAYDDKGQVLTQTSGRSCVSSYQQPAQLSWSCFEPPKLLAEPALLYLELSLLDA
                     NETLVLSANPVIKLEVEGPGACLALDNGDPRDHRPYTALSRRAYGGKLLAIIALDGRA
                     GQLRITARAAGFVEASYQLTVSEAAVNEKLLAYQLDKYSFITNETNKPSKPYARSRGS
                     AVDSLMPNPDSCLKRQGHYLPDNSVMVFSYTTALSRPLTFQPLIKRLLKGNDIILPDW
                     LQPRAAAGQLFTKAFPIDWQLTEAVFSEESRVSGQTLCFGEALELEAILKSDTKGLRI
                     NQELSLVAKKKRLFQSDTQLSYRYQYDTIQAIGAISLTGLKKPLSSLRLVLDYRSSTN
                     APSKQLILSLDQIEQPCHYIMLEEVVDVLSLDLTLEQPIRQAFDLARLQLGLWSMVEE
                     A"
     gene            28360..29244
                     /locus_tag="TV191_000278"
     CDS             28360..29244
                     /locus_tag="TV191_000278"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEL1506829.1"
                     /translation="MLERLSGQTRLTALLAAPARHSLSPKMHNAAYAKLGLDYAYLAF
                     EVGNAELAAAVQGMRALGICGANVSMPNKQAIVPLLDELSPAAALAGAVNTVVNKDGR
                     GHLVGHITDGTGAIRALAEEGVSIKDQIITIAGAGGAGTAIAVQLGLDGAKEIRLFNR
                     KTATFKQAKQLVARINTQTSALASLQDLADDRAFRRSISESSIYIDATGVGMKPFEEH
                     RLITDPALIRPDLVVFDLVYHPAETKLLAFAREHGAKKVMNGLGMLLYQGAEAFKLMT
                     GEDMPVAYIRELLCQNKE"
     gene            29370..30143
                     /locus_tag="TV191_000279"
     CDS             29370..30143
                     /locus_tag="TV191_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEL1506830.1"
                     /translation="MILTQFDPDYQAIINPKDLVAEIDDFPKTVVTCFARATFNRVLN
                     ALPHRLIATTSVANLDIPIYELDVKGHKLGFFNSYVGAAGCVGVLEDIIAMGMKQLLV
                     FGTCGVLDATISENSIIIPTSAIRDEGTSYHYQPASHDIAVNQAYLTRAIDVLEQHSQ
                     TYTLGKTWTTDGIYRETRDKMIQRKQEGAICVDMECSAIAALAAFRQLEHFQFFYSAD
                     NLDADEWDARSLANEADLEAKDNIAFIALELALRLFKDN"
     gene            complement(30475..31557)
                     /locus_tag="TV191_000280"
     CDS             complement(30475..31557)
                     /locus_tag="TV191_000280"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEL1506831.1"
                     /translation="MTQTLQVKSRINDYPIIFTDDIFQPLNQFLAEKGDVKLLFITDQ
                     TVFDLYQPLFRRFQQDYDSYLHIAAPGGQSKSLEEVSRIYDRLIRANFSKKDVIVTVG
                     GGVIGDLGGFVAATFYRGISYVQIPTTLLSQVDSSIGGKVGVHFKGLTNMIGSIYPPN
                     QIIVSAKFLDTLSEREFACGISEMIKIGFIHDRKLFQQLLAFPKDRNQEQLRQMIFQA
                     ICHKKRVVEKDEFEGNLRMSLNFGHTLGHAIEALCHHELYRHGEAIAIGMVFEAKLAV
                     QQQLLSQQDLEALQAAFEAYQLPTTLEAKSMTAEALMTVLKTDKKNSGQHIVLILPTT
                     KGYVSFPIAKHDSRLLDWLRSLLDIA"
     gene            complement(31616..32371)
                     /locus_tag="TV191_000281"
     CDS             complement(31616..32371)
                     /locus_tag="TV191_000281"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEL1506832.1"
                     /translation="MGNDIIADFLNKGCQKSNFIVGPCAIESYQQIRQAAASAKALGY
                     RYFRGGAYKPRTSSNSFQGLGLTGVTYLHEVCQEFSLKAVSEIMSERQLEEAYDYLDI
                     IQIGARNMQNFELLKVLSKIDKPILFKRGLMATIEEYLGALSYLQENGKQNIILCERG
                     VRGYDVETRNMLDIMAVPIIQQKVKLPIIVDVSHSTGRRDLLLPAAKAAKAIGANGIM
                     MEVHPTPDLALSDAAQQIDYQQLEQLGKELWES"
     gene            32809..32979
                     /locus_tag="TV191_000282"
     CDS             32809..32979
                     /locus_tag="TV191_000282"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1506833.1"
                     /translation="MLRYLKAILYLLAPRLAFSVTGVLFPDVFDNLFLVYNILMTLAF
                     WLAIYSVDLPEK"
     gene            complement(33641..33799)
                     /locus_tag="TV191_000283"
     CDS             complement(33641..33799)
                     /locus_tag="TV191_000283"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1506834.1"
                     /translation="MACYSGRVKKLRQVAARSEWVVVPMGDSSTANKMEEAKKLAAFE
                     ATQTLFKL"
     gene            33886..33956
                     /locus_tag="TV191_000284"
     tRNA            33886..33956
                     /locus_tag="TV191_000284"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:33918..33920,aa:Thr,seq:ggt)
     gene            34484..34738
                     /locus_tag="TV191_000285"
     CDS             34484..34738
                     /locus_tag="TV191_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEL1506835.1"
                     /translation="MSYEQDFLRDFEDWVKAQIQVNQLAMATSRQIAKEDNDQRARDA
                     FIRYESKLDAYEFLLGKFDNYNKGKAFHEVPDSLFGSRHY"
     gene            34760..35260
                     /locus_tag="TV191_000286"
     CDS             34760..35260
                     /locus_tag="TV191_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1506836.1"
                     /translation="MARRYNRKKQYKLQLKRQGLLKAVINQVEQTVEKVVDKTKEAVH
                     TASQMVTASKTETADLQDKQSIAEKAAQPKADVASSSLADSSEVSSEKEASKASSEVL
                     SRDAFAELAEVSELRADIVTVLFEAGIRSAAAFSQWTEAELLALKGIGPATISKLKEN
                     GVNFKK"
     gene            35520..36104
                     /locus_tag="TV191_000287"
     CDS             35520..36104
                     /locus_tag="TV191_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1506837.1"
                     /translation="MIEIMGSVENNRLPDVKTSRLLLRQRTLADVEAIFAYASRPEVS
                     YPAGFPPVKTLEEEEHYIANTMPKRWLLQQLPAGYGIALKGDNRIIGSVDFNNRHADD
                     VFEMGYLLHPDYWHQGIMTEAASALLEVAFTLLKLHKVEISCYDYNMGSRRIAEKLDF
                     TLEATIRDRKDAKGNRCADLRYGLLKREWERQCR"
     gene            36304..36867
                     /locus_tag="TV191_000288"
     CDS             36304..36867
                     /locus_tag="TV191_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEL1506838.1"
                     /translation="MNIILIGAQASGKMTIGQELEKLTDLTLFHNHESIDFVTKFIPM
                     SSEARELIDELRLLFFKTFAKRQQSIIFTVVIDFNAPEDIAFLETLQSVFHDFDREVL
                     FVELEIDLKERLRRNKTENRLYHKPIKRHLEWSEKDILDTAKFANFNPAKVPENLKYY
                     CKINNTSLSAQETAQFIVQKMKELEVS"
     gene            36880..39531
                     /locus_tag="TV191_000289"
     CDS             36880..39531
                     /locus_tag="TV191_000289"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEL1506839.1"
                     /translation="MSKELSPKYNPAEVEAGRYQAWLDQDVFKPSGDKKAKPYAIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLREQG
                     ISRYDLGRDKFLDKVWEWKDEYAATIKEQWGKLGLSLDYARDRFTLDEGLSKAVRKVF
                     VELYKKGWIYRGEFIINWDSAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALQVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGQHVVLPIVNKLIPIVGDEHADPAFGTGVVKIT
                     PAHDPNDFEVGGRHNLPQVNVMNDDGTMNELAGEFAGMDRFEARKAVVAKLEEIGALV
                     EIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTDDKVDFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNEAGDMYVGEEAPAGDGWKQDEDVLDTWFSS
                     ALWPFSTMGWPDVDSEDFQRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRKPFSNVL
                     IHGLIRDEEGRKMSKSLGNGIDPMDVIEKYGADSLRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLEQASANVEQVASGAAGNVTDCWILHNLNETIGKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQYAEGSIVTADYPTVDPAFENEAAHKGVESLKDLIRTVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPERLKIASSIVTPELAMSA
                     VITGAEIFLPLADLLNVTEELARLEKELAKWQKELDLVSKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVERIKEMEKLVR"
     gene            39744..40232
                     /locus_tag="TV191_000290"
     CDS             39744..40232
                     /locus_tag="TV191_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013642832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HEL1506840.1"
                     /translation="MTTAATKASVPHKEKMESKEPETSHQPEAYPDLASYQELAVHVS
                     IADQVMTIIGDGKVIFKTSVSTGAKESPTPTGTFVIEPERGDFFFNQASEEGAYYWVS
                     FKDHGIYLFHSLPTDQYGNEIPEEAERLGQPASHGCVRMSRADAKWFYDNIPEGISVT
                     IE"
     gene            complement(40435..41235)
                     /locus_tag="TV191_000291"
     CDS             complement(40435..41235)
                     /locus_tag="TV191_000291"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1506841.1"
                     /translation="MKKKLVMSLIVNLPLLSLICFNEVSANSDYENSPVLGQGYYGYD
                     DYTEAPQIGDQKVIGFRRDWENARDFGVKPIKNNDKEIVVKTSPGSLIRIFKVEEDDK
                     ETELVQVQKKSNGDLTNNRYYPIAKWDGKIVFSLESARTQKTNSKEETYVPYNKIASN
                     GDKFRVHITSDGFVLGSEIWIVGESKPQDIIEQEQKKAQKELEEQKKQENLRQQIKKE
                     REHSQKRVVENIYLKEIRENAHKSWHKRLNEKIQEQWSKFTVFLNKYY"
BASE COUNT        11354 a         8285 c         9597 g        12039 t
ORIGIN      
        1 gaaaggagtg ctttcaaatg ttatcagggg agcatgatgg ctaaagagag acctcagagg
       61 aaactcagtc tttgaagcat taagacagct ttctcatatt ggttacgggt attagaaatg
      121 cgcttaatcg gtgtcaacag ttttcgtatt accatttaag acgtttcgac gacattttaa
      181 gacttaaata ctgaaagcag ctggtaatat gctatactgg tgccagttgc taaacatagg
      241 aaatattcat gtggacgaca gcattgatga aatatttaat gcttaggtac tggtagactt
      301 gcttatgttg aggctgaaaa aattaataga gtttgtgacg cagctattgg aggaataggt
      361 ggcgcactga cttgctaaga aagggcaagg tgttgtaatg cttaataaaa tgaagcgact
      421 acattatttg atgattttta ggctattaac tggtcagcta ccagctatta gcttgatggc
      481 tgttcttctt tcaaaagaca ttcataggct ttctttggga tcactgatta gttttgctat
      541 ctttgcggta agcactgctg cttctaatta ctatttttca cgagaaattg cgattgagca
      601 gttgaaggaa caaacacgtc ccaatctgtt attaactcag atcctgttta tagtggtgtt
      661 tatgattata ggcattgtgt caatctattg tggtctaagc tcgtctgagt tttataagca
      721 ggttattgct gtgatatgct cttttatatc atttgtcact atgggattga tgatttgggg
      781 gatcagatac gcaaaagctt atcgtcgtta atagcttgag gtggtactgg tacttgaaat
      841 cacctcctta accagttaat cataagctat agcactaggt atcagcctta aagcgacgat
      901 acctagtgtt tgtgtgctca aacgcttaaa atagcttttg agggggtaga gctgtctatc
      961 tgcaagcgat atgacaacct atttcattta gggatcaggc ttttttacta tcagtgtttt
     1021 tgacaaggcc cttgttttgg agtatactgg gaaaactagg agggctatta atgcgtagga
     1081 ttcgtttagc aaccttagca gatgctaagg ctttacttga tatttaccgt ccttatgttg
     1141 aggaaaccgc tgttaccttc gagtacactg tacctagctt gaccgagttt gagcgacgtc
     1201 tgtctgacat tatggtcttt tatccctgtc tagtagtgga agaggaggga ggcattttag
     1261 gttatgccta tgctagtcgc tttcatgcac gcgcagccta tgcttggtct gctgaggtga
     1321 ccatttatct ggcccaggag gctagaggga gaggcttggg atcagccttg tatcaccgtt
     1381 tggagggtta tctgaaaggt atgggaatct taaattgtaa tgcctgtatc gctagtacag
     1441 cgcatgctac gccttatctg accaatagca gtcaagtctt ccatgaaaaa ctcggttatc
     1501 ggttggttgg cagatttcat cagtcgggct ataagtttaa ccagtggttt gatatgattt
     1561 ggatggagaa actgctggga gagcatgacg tacgccctcg cccagtgatg tcatttaggg
     1621 attttctttg ccagaagcac cagtctgaat gacaccttat aaaagcttag attaatacaa
     1681 aaggattagg tcctgtcaga ggaagctaat ttttttgtat tgtttgacga gaagttttga
     1741 ctgataaccg caatcataaa aaaactcttc aggccctgtt ataaaatggt ggtagcagga
     1801 gatggttatg tctgagcttg tcactaggtc agctacagca gtcctagtgt catagcttta
     1861 aaaatgagaa aaaagaaatt attttttaag cttggtcttt ttaatatctt tttttgccct
     1921 tgacaattct gccaatgagc tgcaaaaaaa cttaagctct ttcccaaaaa gcttttatga
     1981 tatgatacac ttgtgttgta aaaggatcct gatactagtt aagatttttt tactttattt
     2041 taacaaagga gagtacacga catgaaaaga agtgtaaaat ggtttatgag ccttggcttg
     2101 gttggagctt tcgtagttgc tgggatatct aatgttaacg cagagactag gcaccctcat
     2161 ccaaagtata aggacacttg ggaatttgga attaccagtg ctagctgatc ttactcaaac
     2221 gcttttcttg gagttcctat tgggctagga agtagtgctt ctgtgacaga cttttgggga
     2281 aatgtaaata gtaaagatag tcaaaacaat ggttgggctc gtgccggtgt aaaaaagcag
     2341 tggaattggg ttcaagcaaa gtcatgttat ggctggtatc aggtttaatg ttttattgta
     2401 cgttttagtg gatgaagata ttatcctctt agtcaacttt tctcaaggag gtttttatga
     2461 ggtggagagc tacagttatc tgtattttcg ttctgctttt gacatgttta tcatttggtg
     2521 cggtcaagga gtatggcaat gatatcaaat accctgttca ggctgcattt tcattagtgg
     2581 cttcaaacaa agatgttgat aagggacacg ttttagacag gatcgaagcc ttagccgagc
     2641 aggaacatat ccaaatttat cgtccctact tagatcatac tggtaaagaa gccacctacc
     2701 tgtttgggac aaatgggaaa aagactgtct atagcagtaa tcgcaaggag ctcttgacaa
     2761 acgatcttag tggcatgtac tacacgacga ggtctcttcc ttcatcattt gaaaccgcga
     2821 tgactgaacg gggcttgacc tacaaaggtg ctgatttacc ttggtatctc ttgccttatt
     2881 attttttgtt cacaaactta cgatccttag ctatttggac cctctttttt gtgtttgccc
     2941 tcctcttgtt tgctgttaaa ttgatgtatg ctaaaaagtc tatgatacta agaagcctgg
     3001 gcttatttga acactatagc cgcaaggagt tgctacagga tttgttgctg atgggagcta
     3061 gctttgcggt tagtattctc ctcttcattc tctatcaagg cagtatctcc aatgtttttg
     3121 tcaagtcatt tacacttctg atcttgacta atgctgtcat tttattattg ctgatgcttg
     3181 ctgttcatgc tttatttttc atcaatatcc gttcgttgaa ggcgctagcc attctaaaaa
     3241 ataaacaagc aacccctttg gtcctctttg tctggttggt ggggatttgt ttgtctagcg
     3301 tcatttttgg gctttcccta cacaaaagct tggagactat aggaaaatct gccaatgaca
     3361 ttcaagttct aggaaaatgg gataaagcta aggattttgc ggaaataaca tggctagata
     3421 ccttgagtac gcatactgat gacaatcacc aaattgatag tgattatttc aaggaagaaa
     3481 atcagcgcta tcaacatttt ctcctgtctt tttctgataa tgacgttatt tattcagcac
     3541 tttcaagcct taacgaaacc aatttacaat cagctcctga tgacttcaaa aaagagttaa
     3601 agaccaatgg ggttgatcca aggattgcgt caaaagtccg ttatgtcaat cagggattta
     3661 tgctaaaaaa taaagacatt ttccctaaca atgattacgg aaggccagca gctgatgctg
     3721 taggagtcat ttatatttct aaacatatga tgggagatgc tgacagcatt ttaaacattg
     3781 tcaattatga atggtttcaa tatagcagcc taaaggctaa tcaattggtt gttcaagagg
     3841 ttcctgacgg acaaaagagc tttctgttta atcataagca agaccaacaa gacatttttg
     3901 ctcagcaaga agaagtgaat actatattag tgcagttaaa cttttcgttc atgacggagc
     3961 catcattatt gacgaagttt ggagaaatgg ctcaaaaatc tatctatcgt caggcgctta
     4021 ttcgtgatcg attaacacaa gcaggcttga cgaatttctc tagtttgacc aatgtttcca
     4081 atcatttgat tttagagcgc cataaaatcc taagccagct catcggaagt gttattgcct
     4141 taacggtcct tgccattgcc cagtgcttta tcatttatga atacattgtt tctctgatga
     4201 aacaaaaggc caaaaagatt tccgtctggt tcttgatggg gcaaaaaagc cttgttttga
     4261 ttggtagatt gttattgccc ttagctttgt gtttgtttct tgccatagga atgatgggaa
     4321 tccttactgg aaataggctc atggtactag gcattggcct gctttattta ggagaaatcg
     4381 tttgtatgtc cttttttgct tatcaggcta ttttgaagca tcggattcaa atcatcaaag
     4441 gagattttga catattatga ttgagataaa acagctttcc aaacattatg gaaaaaagac
     4501 aatttatgac aagcttagct tgacttttga ggccaatcgt tcttatgcac ttgtaggtcc
     4561 ttcaggatca ggcaagacca ccctattaaa tgctattgct cgccttgaaa agccagatag
     4621 tggtcagatt ttagtaaatg gtcaagacat ttggagcatg aaagagcaag attattttaa
     4681 ggattatttg ggctatgttt ttcaaaatta tgcactgata gaggaagaaa cagtctatga
     4741 caatcttaaa atgctggctc ctaaatctaa cattgtggaa gccttgcata gcgttggctt
     4801 agacagtagt tttctctcac agaacattta tgaattatca ggtggtcagg ctcagcgtgt
     4861 tgctattgca cgcctattgt taaaaaaggc ttgcattatt ttggcagatg agccaacggg
     4921 tgccttggac aaggaaacag gtgatgagat tattgagctg ttgcttagtt tggtgagccc
     4981 tgatactgtt ctgatttttg ccactcatga cccaaatgtg tttagccgcg ttgatgacat
     5041 catcgacatc tgtcatctac aatagaggca agctctgaga catttagtct ggactgtcga
     5101 gctacagcaa ttagcttgac aatgctgtta ttcctttgtg tcaggaagag attgctattc
     5161 ttctatagat ttttcgaata gacaatgctg aaagtcctta gcgttaatgc taaggacttt
     5221 tttgtgattt aggtcaaggt agtggtaatc tggttataga tgagctgatt cactcttttt
     5281 ccaagctagg gttaggattt cgcccttgcc aagctcagct ggtaggggtt catgctgatc
     5341 ctcttctagt aggctggtaa cccttgctgt gtggtctggg attgctaggg taagagcgca
     5401 ggccttgtca tttgatacat tatagctgcg cgtgattagg gcattatcgg ataggcgacg
     5461 cttgaaggct gtgagagcaa cgtgatcagt tgctcctttg atgtaagcat attgagctgg
     5521 cagctggcca gaatgcctct tggtttgcgc catggtgact ggtacctgag cctcctgagc
     5581 tcgccaatag ctggcaaagc gtgtggtagc gttaatgctt tcaaagctaa agctgacagt
     5641 ctgttgaccg aggcattgag catcaggggt tgggaagtag ccccaatctc caagctcacc
     5701 gacgcttcgt aggagcgtga tagcgatggt attggtatct ggtaggattt cgtattcatt
     5761 gaggccgtaa ttgcctacag tgacaccagt cctaccatca aaaaggctga caaaggcctc
     5821 ctgatgctga ggattggttg ggtttttcca gaattgggca ttggtatgat taggccgctt
     5881 tacggtttca aaaatactat ctgcaaaatg gtggtctgtc tttaaatggg ttggaaatag
     5941 cacgcgcaag cggtggtttg tcatttgatt gttaaagctg gtctgaaatt gtaggcgtgg
     6001 gctgtctttt tccatacgaa taactgttgt tactgtaaag ggcgcttttt cctgtgagcg
     6061 tttggcctga cgctctctaa tgtcaatgac agcctccatt tcagccttta gacgatcatc
     6121 tgtagctaag ggaatatcaa aggtctgtgt caattcgatt tcagcaagat aggctgtgtt
     6181 ggtcaagacc cgcaacttac agctcccttg atgagcaagg taggggctat catgatctgg
     6241 ctggcgaaag atatattcgt taccaatatc accacaatcc tcgtattgga gacagctgtc
     6301 aaacctattg ccatttagct tgtcttcaat cgttagaagg ccatttgctg cgatgatgac
     6361 ttttaggaaa tcattttcaa gacagctcct gtcctgatga aagagcattt tgtcagtgtc
     6421 agttgcttgg caaggctgat cagtctcttt tagtgcaaga cattgccatg acatagcaga
     6481 aagagtcagt gggagcctta gctgtacctt gatggcaaag taggcttctc tgaaggtgcg
     6541 ctctggcagg gcataatcaa aggcgatgtc tgtgcctaag atttcagcct cctctatgat
     6601 cctgccagct gcgtcaataa cctgaaattg tggctgtctt gtctctaggt attcctttgc
     6661 ttcttgataa acagctttag gcagtcgttg cccaaatgga aaaatcttcc atgtcagggt
     6721 gaggtcggag accgtttttt tctcatgacc gcaggtattg aagaggacaa aaggacagct
     6781 atcctctgga aacatggagg tatcaatagc ctcagctatt tggttggcag aacgctctgc
     6841 taagtaagtc cccacctcat aggctttatc aaagcgaggc atcatctcct ggtggacact
     6901 atcaacacta cagccacaaa tggagtcatg agggtggttt tgcatcaatg ttttccaagc
     6961 atagcgcagc tggtcgtgag gataggtacc tgtgacctca aaggccatcg tggcaagagg
     7021 ctctgtgata ttttcaagct gacgagacac tctggtatta gcctgcttga ggtaaattct
     7081 agcagaggca gtgttggcta aggtatacca gccgtccgtt tcttggctgg tcatctcacc
     7141 agacacaatt gagagctcct caggcagctc ctgacttaaa tcagccaaat agtcctcaaa
     7201 gcaagagtgg acaaagtcgt aatcagggta gagcttattt gcaagggcaa ttgccttggt
     7261 aacgtctagt tgaacaggct ggtgatcaac cccattcatc atcagcaggt gcctggtaga
     7321 agcaaagcgc tcagcgtctg ctagcttttg atcccagaat tgtcgagcct ttttctcctc
     7381 ggttgggatt tcgttgccat tgctgtacca attggcaaat aataagccga gaatgcggct
     7441 atcatcaggt ccctgccaga tcatttcaga aaattgggag ctgtattttt cgcttgtatc
     7501 cacttgattg ttaaagcctg taggcctgat accacgtcca aaggcagcgg catttagccc
     7561 tgcttttcgc attagctgtg gtgtttgtcc catatttccg aaggtgtctg gaaaataacc
     7621 cagtggaacg cttgcccccc attgctcaca gtcctctttg ccaaccagca tgtttcggac
     7681 attggactca ctgctggtca aaaaggcgtc ctgtaggata taaaaggggc caatacgtag
     7741 cttaccagcc tgaatggcct gtctaatctc ggcctcacgc ccaggcttga cctgcaaata
     7801 gtcatctagg ataatggttt gcccatctag atggaagcta tgaaaatcag ggtctgtttt
     7861 aaaaaggtct agtaaatcgt caattaactg gatcaagcgc atgtggtgct gctcataagc
     7921 catgtaccat tcgcgatccc aatggctgtg tgaaatgata tgtacttttt taggtgtcat
     7981 cactgactca ctttctaagg gctaatggta aagcccagat aatcaagaag aagctcacaa
     8041 aacatcatgt ttgcccatga gaaccattca cgtgtatagt gactcggatc attgacgtca
     8101 aagccctcat gcatcaggtg ggtgcctgcg tcagtagcca ccagtaaatc aagtatatct
     8161 gctttatctt tttgatcaag tgcagttaag ccctgaaggg caagtgcaat atgccaaata
     8221 tagtttggtg gcgtgtggga ggagccaata ccagaagcag cactgccttg gtaataataa
     8281 ggattttccg ggcttaaaat ggtttgacga gtggctaggt aaatagggtc gtccttggca
     8341 caaaagccaa gatagggtgc cgcaaggagg cttggaatgt tagcgtcgtc catgatagta
     8401 tagtgcccca ggccatctac ctcataggca tagatgatct ctccttggct gttggttaca
     8461 agagcatgct cctcaatccc tttttgaatg gcaagcctaa gtgcatgagc tctcctagca
     8521 atcgtttgat ccttaaagag atcagtatag agcccttcaa gataggataa gacgacagca
     8581 gcaaacatgt tggacggcac gaggtagccg tattggcagg catcatcgct tggtctaaag
     8641 ccagaccaag tcatgcctgt ataggcaaca ggagctccct taccgttgtg ggtcaaggta
     8701 tcctccttac gccaggtgtc gcgctcaaag ctgtaaggag aggcagtgtg gtcttgctct
     8761 gtgctccaga catcaaggat cagcttgatt cctctgtgga aatcctcatt gaaatgctct
     8821 gtacagtctg tctctcggta gagcagatag gctaactgga tcggatagca gagggaatca
     8881 atctcatatt ttcgttccca aatccaaggt cccatctggg tgtggtctgc ttggtggccc
     8941 ttgctatttt cctcctcgtt aaaggcgttg gcataggggt caatgcaaat gtaacggaac
     9001 tgacgtttaa cgagacctgc tatgatttgt ctcatgccag catctgtctt ggctaaaaag
     9061 agataaggct ttagttgcgc agttgaatca cgcagccaca tggcaggaat atcacccgtt
     9121 agaagaaagc tggtcccatc ttcgtcgatt tttagggtcg tttccaaggt gttggcaaag
     9181 ctggctttaa aattaatggc ccagctacgg tgctcttcac cgcagagctc ttcaatcgtg
     9241 tccataaacc tgagcacact gctaggaata ggtcttgtca tatcatatcc tcctaaaaga
     9301 tatatcattt gatatctttt ttaattataa gatataactt tatttttgtc taccacttta
     9361 gaaaaggttt acaagtcttt tttttcgtga tatactgcta gagggagtaa aaaatgactg
     9421 aattactata taaaaagata tatcatttta tcaaggaaca aattgattca gggcaattac
     9481 aggcaggtga ccgcctacca acagaaaagg ccctatcaga gcaattttcg gtgagccgca
     9541 ttacctctaa gcgagcctta gtagagctgg agcaagaggg cttgattaca cgcagcagag
     9601 gtaagggcag ctttgtgacc gatggcccac caccgtctac tcagcctaat aaggacattt
     9661 tgttgatcct gccctttgct tctgattacg aattgggaga ttatgctaaa ggaatcatga
     9721 cggtcgttgc tgacaaaggc tatcgcctga tggtccagct tacaagtacg gtaagcttgg
     9781 aggagctagc tgattatgct ggtgtgattt attatccaga agacgttaat catagtattg
     9841 agctgctctt ttattgtgcc cagcgtgggc ttgctctggt gcttttggat aaggccttag
     9901 acctgtttga ctttccagca gttgttgcag acaataaggg cggagcctat gagttgacca
     9961 agcatttgat tgatcaggat tgccgtcgga tcatgtttgt ggcaactgct tcctttggtg
    10021 aggtttcctc tgttagagat cgttatttgg gttatttggc tgcgatggcg gaaacagagc
    10081 ttgaggccaa ttattttgtg aagctgaagt cagaaagcaa tgctgcttat cttgagcgat
    10141 tggttgatga gctgacggct gctacagctg aaaagactgg tttagtggtt gaaaatgatt
    10201 ggctagccat tcaattgatc caaaaaattc tacaggtcgg gctatctatt cctgatcagg
    10261 tagctgttgt tggctttgac aacagccaag cctctcagtt aatcagccct caattgacaa
    10321 cagctgcaca ggatttttac cagatggggc agcaagcagc gcaactattg atagagcggc
    10381 tgactcggcc tgatcagcag acggcgtctt gtcagcttcc tgttaaggtc tttatcagag
    10441 aaagcagtca aaagtcccta gaaatgctat aaaaaggaga agtgtcatgt ctatttatca
    10501 agccctcaag gactatcagg aggtgataac cagaggtgat tacctcgttt ttgacgcccc
    10561 tgtttcctgt cgctttgttg gtcgtttttt ccgatttgag aaccaaacag ctatgaagcc
    10621 tagtcttaca gcgtcagtct atgtcaactg ggttgaggag ggagcagctg acttgaccct
    10681 taagcacgtt tttaaccgca ccttagctag ggatgccttt accttgacca tttcagagga
    10741 taaggagctt gtgattgaaa gccaaaattt aagaggcttt cgctatgctc aggaggcttt
    10801 agaaaaggta atgactgtta aagagggcag gctttatttg ccgattgttt cggttaggca
    10861 tagtccgtcc tttgccatgc gtggtgtgat tgaaggcttt tatggcaccc cttggacgcg
    10921 tgaggagcgt ttagattgct tgagctttat tgctgataag ggcatgaata cctacatgta
    10981 tgcccctaaa aatgatgact atcagcgcag ccactggcgt gagccctatc cagaggattg
    11041 ggtggctcat tttagggatc tgatccagct tgccaaggaa agacaggttg acttttggta
    11101 catgattagt ccggggcttg attttgacta caccaaggaa gaggactatc agctgctcta
    11161 tcaaaaattg cagcaattgt tggatttggg tgtttgtcat tttggcctgc tgcttgatga
    11221 tattgattac caaatagtgg cagcagttga gagacgtttc aaaaaaacag cctatgccca
    11281 agcacatttg gcaacagctg tttaccagtt tttacagcgg cagcatgcag cccctgactt
    11341 ggttgtctgt ccgacagagt atgataatca tcatgactct ctttatttag cagagttatc
    11401 agaggctatt cctgctgagg tggctttttt ctggactggc ccaagcactc tggccagtca
    11461 gatttctcag gcagatattg agacaatagc agccatctac cggcggccca taatcatctg
    11521 ggataatatc cctgtcaatg attatcagga cgattctaag aggctctttt tgaccccgtt
    11581 tgccaatcgc tctcctttct tgtgtcagcc agactatcag gtcaggggga ttgtgtctaa
    11641 tccaatgatt agctgggaac tatcaaagcc gactttaatt gatatgagtc gctacctgtg
    11701 ggacgccaag cgttatcagc caagctattc ttggctagag gccttgagag actatactgg
    11761 agataaggct atggctttag cgcttttgcg ctttgcttgg cataatggca atcgtcattt
    11821 gcacagggat ctcccctttg aggtggagga ggcccttatg cgtaaggaca tagctagctt
    11881 atctggttgg gtagctgagc tggtagagct ggtggataag ctgaaagagc ttgatattcc
    11941 tgcgtttcaa caggctattg ctccttggtt tgatcgggct aaggctgatc agagcttttg
    12001 gagggttatt ttagagcaag cgcctgatct tgagcagcaa tatgctgagc ttcaggagca
    12061 aaggcatcga attggaagca atattccaag ccgcttttat cagttgcact atcttcagga
    12121 gaatagcatg ctaggcaatc aggcacaggt cgctgaagct agagctgagg attatactta
    12181 attagtttat aagggagaac aagggacatg ctagagtttc cagaaggatt ttggtgggga
    12241 agtgctacat caggccctca aagtgaaggc tgctttcaaa agccgcatcg caatttattt
    12301 gattattggt atgagcaaaa tcctgagctg ttttatgatt atgttggacc tgatacggct
    12361 tctgattttt ttcatcagta tgatcaagac ctagctttat tagcgtcttt gggtcacaat
    12421 tcctatcgga cctctatcca gtggacacgc ttaattgatg attttgagac agccacgatc
    12481 aatcccgatg gactggctta ctataacagg gtgattgatg cctgcctagc acatggtatg
    12541 cgtccggtga tcaatttgca ccattttgat ttgccaattg ctctttatca gaaatatggc
    12601 ggttgggaat caaagcatgt tgtggatttg tttgttgcct ttgctagagt atgctttgag
    12661 cagtttggcg atcgcgttaa ggattggttt gtacacaatg agcccatggt tgtggtggag
    12721 ggctcatacc tgctgcaatt ccactaccct gccattgttg atgggaaaaa agcggtacag
    12781 gtggcttata atctagcact tgcaacggct aaggttatct gtacctacca agaacaagca
    12841 gcagagctga gcaatggcag tgttggtacc attctcaatc tgacaccgat ctatccggca
    12901 actgattcag aggctgatct tgctgctgct catgttgcag agctgtggca caatgacctc
    12961 tttatgtctg ctgctgttta cggtagcttt ccaaaggagc tggtagcaat actacaaaga
    13021 gatggagtgc tctggcagtc cacaccagag gagctggatc ttatggctgc ttatacggtt
    13081 gattacgtgg gcattaattt ttaccgccct aagcgcgtga aggcgccaga ggttattcct
    13141 gtgattagcc cttcctggag tcctgagtgg tattatgatg cctatctgat gccgcagcgt
    13201 cgtatgaatg tggacaaggg ctgggagatt tatccagagg cggtctatga tattgctcta
    13261 aaaatgcgtg atcagtatag gaatatccct tggtttttat ctgaaaatgg ggttgggatt
    13321 tcaggagagg atcgttaccg agatgagagc ggacagattc aagacgacta tcgcattcag
    13381 tttttaaaag agcacctgac ctatcttcat aaggggattc aagcgggctc taattgcttt
    13441 ggctatcatg tttggacacc tattaattgc tggtcttggc taaatgccta taaaaaccgt
    13501 tatggtctgg tagaaaataa tcaccgcact cagcgtcggc gtgtgaaaaa atcagggtat
    13561 tggtttaagg aggtggcaga ggcaaatgga attagctaag aaaagaagaa aaacacaaaa
    13621 gccagcccaa tctcctttaa agctaggttt agagaagcta agagagattt tacaggagca
    13681 gctagtagct ttagcggttt tacctgctag ggtgatgggt tagcataagg gcttgctgat
    13741 gagctatgcc agtgatagcg attaaggaat gtaaaagagg atttcctaac atcataacta
    13801 tccgtctaac gggtgattta ttgtttcgta cctacggagc gaaacggact aaagtcacat
    13861 aactaaaagc atgtcatggc ttgctgtagt acgagtgatg acatgctttt tttagctttt
    13921 aacgggttag ggagtagggc aggtcctcag ccgaatagtg cttgagtggg ggaactagtc
    13981 ccagctgaaa gtcgagctga cagccctgaa tcagatcatc atgattgatg tagagcttgt
    14041 tgtagctagc ctgattgagc ttgacctctt tgacaaattg gtattgaggg acattgcccc
    14101 tacagctgat ttggatagta ttgccatttg gcagataaag ggttgcctga tctacagttg
    14161 gaataccaat caggtattgc ccagttcctg gtgtaacagg gtaaaggcca aggctgttta
    14221 acaggtacca cgcgctcata ctgccattgt cctcatctcc tgggtagcct gtatcggtaa
    14281 aggcatgact gagcagattt ttaaggatta gctgactgta ttgtggctga ccgatatagt
    14341 gatagagata ggggaggtga aagcttggct gatttgagat agcaatctga ccaaaatcct
    14401 gtgcggctag ctcactcatt tcgtggattt caaagccata gctgtgaacg tcaaacacag
    14461 gctcatgatt gcacagctcc tcaagtcttt tggcaatggc ggcgtttcct ccgatcagtc
    14521 gaatgtaacc tagaatatca tgataaaagg caaatccatt ttgataatag gagccctcgg
    14581 tgtagtcctg cccccagtgg atagggttaa agccacattg ccattgccct tgtcgatcct
    14641 tgcttttgag gtagccggta tcagtatcga ccaaatggcg gtaattgagt gatcgcgtgt
    14701 ggtattggtc actaagtgct gtcttgccca gaagggcagc tacctggccg atacaaaaat
    14761 cactataagc ataatcttga gtctgattga cgctttcctg gtagctattt ggcagatagc
    14821 ctagctcttg atagtcttga ttgcccttgc ggccatagcc tgttccttga ctgtctgtat
    14881 tggcagttgc cagcatagcc tctaaaagct caggcatcag gtcttttctg atgcctttga
    14941 cagctccatc agcaataaca gcatcaacca aggttccagg catcaggcct cgctcatctg
    15001 gagacagcca ttttggcaga tagttggtgt cctgataagc tgacaagagt ccctctaaaa
    15061 tatcagcata aatctcaggt gcaattagag acagcaaagg atagacagat ttataagtat
    15121 cccaaaagcc attgttggta tagtattttc cagcaacagg tctttgactt gttgtattat
    15181 agtgaatcgc ctgcccggtt gcagtgattt cataccatct ttggggaaat agcagggctc
    15241 ggtaaaaatg ctggtagtag gccttgacct tatcaaagtc tttatcctta atgtcaatac
    15301 gactgaggta gctgagccac tccttgcggc tgtattcaag gcttttttca aatgatctgg
    15361 ggaaatccct ctgccaattg agctgagctt gatcaaagct aataaaagaa gcagccgccc
    15421 taagctcaag atgtttgagg tcatcagcaa attggagata ggtaaaggac gtcttgctgc
    15481 aatcatcaag agatttggag tttaagtctt ctccgataag cttttttagc acagggctgc
    15541 taaactgaag ataaacaaac atggctaggt ctttatcctg acagtctgtg atgttttgca
    15601 cacagccaag gattgtttta ccatcagctg tcacctgcca ggagcttttt ccggggttat
    15661 ggataatcaa gcctgctttg ccattatcaa aggaaaaatc acaatgaaag ctgtaggcag
    15721 ctgctgttgc tcgcgtcaaa atccgatgtc tctggctaaa aatctcaaga agatgaggcc
    15781 gaaaagctgc ctccttggga cgataggagg tctgattatg aaacacatct cccttggtca
    15841 gcggtccgct gactggaaga aaagtaaccg tcgcaaaatc accgacccaa gggctgggtt
    15901 gatgtgtcaa gcgaatacct gaaaagctgt gatcatcggg gtgaaaccac caagcccctc
    15961 gatcttgact ggtttcgacg cttagataat gcatgccaaa gggaacccct gtcaatggca
    16021 ggcaatttcc ctgtgaaaaa tggtagtgat tggttgttcc aaagcgggtg tcaatgaagt
    16081 ctaatcgatc cacatctcgt cctttctatg ctcttgcata aaatcaatag aggcacctag
    16141 taggttggcc tcgtttttaa agtggcagat agcaagctgc ggtctcaaat cagaaatgct
    16201 gactatctga tagagcttat ccagttcagc ctcaagggca ggaagaagaa agtcagcctg
    16261 agagacaccg ccaccaatta ggatcatttc aggatcaaag gcatgctgga tattaaacac
    16321 ccccattgcc agactttgaa gaaagacctg tctttccttt agggccacag gatctccttg
    16381 atcagctagc tctaagacct ctttaccggt gtaactttta ccatcattta tgatctgact
    16441 atagcgcttg gccatattga ccacagtgcc taattcgctg aaggtttgat aacgctcatt
    16501 catgaccata aagccaaact cacctccaaa taaatgggca ccgtaatgaa tcctgccatt
    16561 aatcactagg ctacctccaa caccggtgcc aagtaccagc atggcaaggc tgctagtgcc
    16621 ttgtcctgca cctagagcag attcggcaag agcagcacag ttggcatcat tttcaatcga
    16681 aaccggcaga cctagtcgct cctcaaggca ttgctgaatg ggaaagccat gaatataagg
    16741 cagtgcactt gctccctcga tgatacctgt tgctttattg acagctccag gggagctaat
    16801 ggcaattcct gagagctttt ctgtgcggta gtaagccagt cgctcgtcaa gcatatggta
    16861 aaagtcctct aggctttggg gagttgggcg actgctttgc ttttttagcc tgcccttgtg
    16921 acaaatagca aatttgatgc tggtgccgcc tatgtcgata cataataagg tcattgtaat
    16981 tcctcctata acaggtatat taccaattag ctacccttag tatgacagat tttgaagtgc
    17041 ttgaaaagac tttctcggca ttcctatatt ttgtgctatg atacctataa tttgtgttat
    17101 caaacctata atttgttgct tgttctatgt gtaagcgctt gatatacttg aagcatcaat
    17161 tgaaaagcaa agggaggttg ggaagatgac gacaaagatc agcagcaaga aatccttttg
    17221 gaaaaatgtg atcaaatacc gcgctttgtt gctgatggta ttaccgggat ttgtctggtt
    17281 catctttttc ttttacattc cagtattagc taatgtagtg gcttttaagg attttcatta
    17341 ctcagcagga ggttttatgg aaagcctgaa agaaagtccc tgggttggct tagataactt
    17401 taaatacctt tttgcctcta aggatgcttg gttgattacg cgaaatacca ttgcttataa
    17461 tcttattttt ttactattta acgtcttttt tgccatcgct ttcgctatta tcatgagtga
    17521 gcttcgaaac aagaaggctg ttaaggtcta tcataccatg tccttactgc cttatttctt
    17581 atcatgggtt gtgattgagt attttgtttc tgccttttta aatacggata agggctttat
    17641 taatcagctg ctcattgata gcggcaatag cccaatcaaa tggtattcca atcccacctg
    17701 gtggcccttg attttacttt tcatgagtgt ttggaaagga cttggctaca acagtatcat
    17761 ttattacgca tcggttaagg gaatatcaga cacctactat gaggcggcta tggttgatgg
    17821 tgccagtaag tggcagcaaa ttagacatat caccattcca cagcttttgc cgatgatgtc
    17881 tatcctattg attattaata ttgggagtat cttcaaatct gactttggct tgttttatgt
    17941 gattcctaaa aattcaggtc ctctttacga tgttaccagt gttttagata cctatgtcta
    18001 caatgccctg acagctactg gtgatattag tatggcttct gcggccagtc tttatcaatc
    18061 tgtggtcgga acctgtatcc tgctcatcac caatgctttt gttcgtcgta tggatcccga
    18121 tgcagcctta ttttaggagg aggacatgga gaaaaagaaa actgttaaaa gggtcaacgt
    18181 cagaaccttt gacccaaaaa ccaatgctgt ctttaatgtg ttaatcgctc tttttgccat
    18241 ctcttgtatc attcctttta tctttgtgat gattatttcc ttcacagatg aaagctatct
    18301 gatcaatcat ggctatagct ttttcccagc tgcttggtcg acaaaggctt atcattatat
    18361 tttccaaggg gctatgtctc atcggatcat aagatcgttt gcggtgtctg tatttatcac
    18421 cgttttagga acctttatca ataccacaat gacctcaacc tatgcttatg ccatctcaag
    18481 accttatttt ccctacaggc gtttttttac catctatgcc ttgatcacca tgctttttgc
    18541 accgggtatg gtagccaatt atttggtggt gagtaacctg ctgcaattaa aggatacggt
    18601 ttgggccttg attttaccga tggctctggg accctttggc attttggtga tgaggacctt
    18661 ctttaaaaag accgttcctg atagtattat tgaatccgct cgtatggacg gcgcaggtga
    18721 attgatgatt tttatgaaaa tcgttttacc tttggcagtt cctgggattg caaccattag
    18781 cctgttctca gccttaacct attggaatga ttggttcaat gcgctgctct atgtgcaaag
    18841 cgagagcctt tacccgatgc aatacctctt gatgaagatt caaagcaata tacaggcact
    18901 agcccaaaat gctggcatga gcgcccagct atctgatagc ttagcctctt taccaaagga
    18961 atctgtccgc atggctattg ttgtcattgc aactttgccg atcgccctaa cctatccttt
    19021 ctttcaaaaa tactttgttg gaggactaac catcggcggg gttaaggaat aatcacccat
    19081 ttggaatagg tcatacagct gaccgttcca atgattctgt tatcaaaaaa agaaattatt
    19141 ttaggaggct tactgatgaa aaagtggcaa acaatcttat gtgtgacggg agctgtgctt
    19201 gcagctgcta gcttgacagc ctgtggaagc aaatcagctt ctaaggacgg tgaggtgaag
    19261 ctattgatgt atcaggtggg agataagcct gataactttg atgagctgat gacaattgca
    19321 aataaacgta ttaaggaaaa aacaggggca acccttgatt tgcaatacat tggctggggt
    19381 gattgggacg acaagatgag gatcattatt gcgtcaggtg aaaattacga cattgccttt
    19441 gccaacaatt atgtggtcaa tgctcaaaag ggtgcctttg ctgatttgac taagctaatg
    19501 ccaaaatacg ccaagaaaac ctataagaac ctagatccgg cctacattaa aggaaatacc
    19561 attgacggta agctttatgc ctttccagta gatgctaacg tctatgctca gcaaatgctg
    19621 tctttcaaca aagaattggt agacaaatat ggccttgaca tttcaaacat caattcctat
    19681 gcagatgctg aaaaggtctt gaaacaattc cacgaaaaag aacctaatac tgctgccttt
    19741 gcgattggtc aagtctttag catgtcaggt gactacgatt acccattgac caaaaatcaa
    19801 ccatttgctg ttaaaatcga tgaaggcaaa ccaaccatca ttaatcagta cgaagatgag
    19861 ccctttaaag caaacctacg cttgatgcat aaatggtata aggaaggctt gattccaaca
    19921 gatgcagcaa ccaacacaga aggctacccg cttgaaggca atacctggtt catgcgtgaa
    19981 gaaacccaag gtcctatgga ctatggcgat accatcttga ccaatgctgc tggtaaagac
    20041 attgtgtcac gaccattgac aaagcctctt aaaacgacct cacaagccca aatggctaac
    20101 tttgtcgtgt caaatgtgtc taaaaataaa gaaaaggccg ttgaagttct ttcccttctt
    20161 aacagcgacc cagaattgct aaatggtctt gtttatggtg ttgaaggcaa ggcctgggaa
    20221 aaggttggcg acaagaaaat caagctgctt gatggctacc aacccaaaat gcacatgggt
    20281 gcttggaaca ctggtaacaa caagatcctc tacacccaag aatcgatcac agatgatatg
    20341 attgcaaagc gtgaccaatc aatcaaagac gctaaagagt ctccgatcct aggctttacg
    20401 gtagatacca aggcaatcaa aacggagcta tcaaaaatct caaacgtgat gaaccgttat
    20461 aaagctagta tcaatactgg tacagtagac cctgatgaag ctcttccaaa acttctttca
    20521 gaccttaagg acgctggttg ggacaaggtt caaaaggaag tgcaaaagca attggacgac
    20581 tttgttacaa aaaataaata aggcaatgga ctttccttgc aaggtggtaa gaactgggga
    20641 cagcctcagt tctttttagc tcaagcaggc atacaagagc tgacagataa ggcctctctt
    20701 agaaaaaagc cagagcctgc ttgcaaggca gttggtccac caaagccctt gctgacaagg
    20761 ttttaccagc cttagtcggc tgtcctcttt ttattaagct tttgtcacaa ttagagtaaa
    20821 atatgctata ttagaagtat ctcatcttat catcatgaca gctaagacct tagtcatctg
    20881 gctgagggat cgttgcttct cttagggcgc tattggtcct acaaaggata ctagaaaagg
    20941 ataatcttat gacaggaatt gaaaaagcct gctttctcat ctggaaaatg atgcagctaa
    21001 cccttatatt tcatttgctt tccttatgtg gtgctgtgat ttttggagtg gggccagctt
    21061 ggcagaccat tgttaccttg tttttggaga ccagtcagca ggagaaacat tattcgctca
    21121 agcgggcctt tcagatatgg cgtcgggtct tcaaagaggc caatctcagc tttttcttct
    21181 ttggattatt gctattattg ctgaatacga gcctgtactt ggccattcaa tttcaatcgc
    21241 tgctgtggtt tagcctatcc tttattatca tgtttgtcat ggtttggctg gtgatgattg
    21301 tgatttacat gaccttttat gcagtgacct atgaaattgc tttttgggag aatctcaagc
    21361 tgtcttttat cagtattttc ttgaatgcca ggcagttttt gttgaccctt gtggttttag
    21421 ctggagttgc ttggtttact tggcagtata agggcttgta tctttttctg agctttggtg
    21481 cgctggtttt gttgctggat atggtcacca agcctaatcg tcgcatggta gatggagtca
    21541 ttgatgacaa gtaaatcttt aaagcggttc ttgatggagc atattaagca gggcttttta
    21601 attaaccgct tgatgaaaat atatagcctg tttatcgtgg ctctctttag cttaagtgcg
    21661 gttggtctaa gcacctattc gattcgaaat acctaccaaa tggttgacaa tcaaatgcaa
    21721 atgcggctag atgagaccct agcaaggcta caatctcaaa actatattac cctgcgcgtg
    21781 ctggagcagc tgatcgggcg tccagaggat tatcgaaatc tgtatcagta catgatattg
    21841 acccctaatc aatatcttac taaggttttt gaggattggg gtgagggcaa aaacacacct
    21901 ctgttttcag agcaggtcag aaggcttttt gatttgtatc cagatttaga tgggctgacc
    21961 ctgatgctgg acgatagcac gtcctatttg tatgcagata ggtcgattaa gaccggccgg
    22021 ctcttatttg gtaagcctca gacgctaaag ggcaattact tagtaaggtc cattcgccac
    22081 cctgagtcag gtgatgttac aggccgcctc tatctgcact ttgcaagccc cagcacgatg
    22141 ctacagcctg agcagcataa gtatctagcg acctttgcct ttgattacta tggcagagag
    22201 ctctttcatc agggaggcgc tgcctttccg gagcttgaag caggtcttaa aaaggcgcta
    22261 aaggcggatc aggctattga tttgacagct ctcagcaaga gctatcatat tcagtacaat
    22321 cgctcgggag acttgctggc ctatgtggcg gtcaaaaggt cttattttat ggaagaggct
    22381 gtgcgtacaa tgctcctgta tggccttggc tcgttattgc tagcttggtt attgctacag
    22441 ctccttttca gggtatttcg caattatatc cgacaggtct ctgagattac agatactatt
    22501 gaaatggttg cagctggtga tttgtcgtta aggattgaca acagtcatat ggaattagag
    22561 ctgtatcaca tttctgaggc gatcaatcaa atgcttggca acatcaatgc ctacatttta
    22621 gaaatctatg tccttgaggt tgagcaaaga gatgcccaga tgcgtgcctt gtcatcacaa
    22681 atcaatcctc attttttgta taacacccta gaatatattc gcatgtatgc gcttagctgt
    22741 cagcaggagg aattggcaga tgtgatttat gcctttgccg ctttacttcg aaataacatc
    22801 agccaggata aggtaaccac tctaaaagaa gagctggctt tttgtgaaaa gtacatctat
    22861 ctgtatcaaa tgcgctatcc agatagcttt gcctaccatg tcaagcttga tcctgtcgtg
    22921 gctgatgtgg aaattcctaa gtttatcatt cagcccttgg tggaaaatta ttttgtgcat
    22981 gggattgatt acagccgcta tgataacgcc cttagcatca aggcgctaga tgaggaggac
    23041 agtattttga ttcaggtgct tgataatggc aagggtatta gccctgagcg cttagtggct
    23101 attgaaaagg gcttagagga gccgcaatcg acggggaata gctctattgg gctgcaaaat
    23161 gtctatatgc gcctatttca caaatatcga gacagagtga cttggtccat gtctcaggca
    23221 ccgactggtg gctttaggat tcagatcaga attagaaagg aagcttaatg tacaaggtct
    23281 tattagttga tgacgaatac atgattttac agggcctaaa ggtgattatt gactggcagg
    23341 cgcttggctt tgaggttgtg gcaacggcaa ggtcagccaa agaagcctta gcttacctag
    23401 atgactgcgc tgtagatgtc atgatttcag atgtcaatat gcctggtatg acaggcctgg
    23461 aattgattga ggcagcaaga gatgtattgc cgcatttgca gaccttgatt ttatcaggct
    23521 atcaggaatt ttcctatgtg caaagggcta tggagctaga gactaagggc tacctcctaa
    23581 agccagttga taaaaaagag ctggtagcta aaatgctcta ttttaaggaa tggcttgatg
    23641 agcagagggc agcttctttg cgtcaggctg cttatcgtga gggcttgata aatctctggc
    23701 ttgctgatga attgagtgag aaagagtttt ttcaactaac gcaggagcaa cccgaggctg
    23761 agcttttagg ctttacggtg ttgtatgtgg attgcaagac ttttagccct gccttagaag
    23821 ccttttttga ggcctccaag cagccctttt acttaaaaaa ggcagagcaa aagaaggtct
    23881 atctagtcat tctattagga cagagccatc aggctaagcg ctttactaat acgcttcagg
    23941 agcgatttta caataccatc aatcagatca ttctaggaga aacggttgtt gattgggaaa
    24001 atgtgtatga aagctataat caggtcagaa ggagcttttt ttacaacagc gaggtgtctc
    24061 aggtagctgc taagaccaac gctaaaattg agctgccgga atcgcgattg cagttttttt
    24121 cctttaacaa gaccttgatg attggggacg agccaactat tgtctccaaa ttacaggcaa
    24181 tctttgagga gatgacagag ctaagcttct ctcctgagga cgtcaagcac gtctcttttc
    24241 tcttattttc agacatttat cgccaatttc cgattttaga tcgaacgacc tacctatcga
    24301 tggtcaagac tattcacgat agtcagtcca ttgatcagat cttatcagcc ttaaaaaagg
    24361 tgcttgagct gacaagcaaa agcaatcagc cccaaaagcg ctattctgat ctggtcagtg
    24421 aagccattac ctgtattcag gaggaatact ctcaggaatt aaccctcaag gctgtgtcag
    24481 atcgcttgca tatcaatggg gtttatttgg gacaacgctt taaaaatgaa acagagtgta
    24541 gtttttccca atacctcaat caggtgagga tccaaaaggc acagcaattg ctgctttaca
    24601 ccaataaatc gattaacgaa attgcctatg agacaggcta taatactaac cattatttca
    24661 taaaaatgtt caaaaaatta aatggtttat cgcccaagga gtttagagac cgttataaag
    24721 ataattatca agctataaaa ggaagctatt aagaaagggg gcgctatgtc tgtagagaca
    24781 atcactggtt caacggatca atctcatggg gatatctatc agcttcactg gattgataaa
    24841 gtagggcgct gccatgcctt ttcaaagggg tggcgctttc tgatggctga tttgcagctc
    24901 gctcaggagc cattttttga tgattcggac tggcagcaga tagctttacc acatgatttt
    24961 agcattaatc agccctatac ggttaatggc gaagctcaaa gtgcctataa gctaggtggt
    25021 gtaggctggt accggaagta ttttgccctt gatccaaagc tggctgacca taaggtctat
    25081 gtgacctttg atggggctta tatggaaacg caggtatacc ttaatgggca tttgatagga
    25141 gagcatgtca atggctatca ggcctttagc tatgatctct cagcctttgt aatccctggg
    25201 caagagaatc tattagcggt tcgggttgaa catctggtgc ctagctcgcg ttggtattct
    25261 ggaagtgggc tttatcggga ggcttttttg accgttcttc cgaaggttca tcttgataag
    25321 gatcggcttc gtttatcctt atcccaggca gcgcttgagg ctgatagcca agcgcttgag
    25381 atagagcttg gactcagcca acaggtcccc ttgagtggct atcagcttag ccttagtctg
    25441 tttgagcagc tggcagatat ccagcagaga cagacagtat atgagagtaa accggtagcc
    25501 ttggacctct tggaggagtc aggtaggctg gtgatgacca ttcctcttag gcatatcaaa
    25561 ctgtggtcgc cagctcagcc ccagctctat cagcttgata tgcttcttta ccataaggga
    25621 gcagtgcttg atcggctgac acttgaaaca ggctttcgac agctgcattt tgatgctgag
    25681 tgtggtttct ttttgaatgg caaagccttt aagctgcaag gggtctgtct tcatcatgat
    25741 cagggtagcc tgggggcatg tgcttatgag gaagctatag ctaggcagct tgttttgcta
    25801 aaggaaatgg gagcaaatac ggttcgtgtc acgcacaacc ctagtgccag aaggcttaag
    25861 gatctggcta acaggcttgg gttatttctc attgaggaag cctttgatac ctggacttat
    25921 gctaaaaacg gtaatagcca tgatttttca agccattttc acaagacagt gggacaccaa
    25981 aatgcagcca ggctaaaggg agtcactaca gcagaaacca cctgggcgca atatagcata
    26041 caggccatgg ttctctcagg tcttcatgat ccatctgtct tgatgtggtc aatcggcaat
    26101 gaattgttag aaggcttctc agctgatgtg agccactacc cttatgttgc taaggagcta
    26161 tgccagtgga tcactgagct ggatcagtca agacctatta cccttgggga taataagctc
    26221 aaggacaagc attttcattg ggcgcaggaa acaaaagcgt tggcagagca ggtcaatcag
    26281 ctccagtccg tgcaaggagt gattggactt aactatgcta aggccagaga ttatgatcga
    26341 ttgcataggg acaacccgac ttggctgctt tatggctcag agacagcctc tgctattaat
    26401 agtagagggg tctatcatct caagggagga gctagtcagg atcatgagct aacctcctat
    26461 gaccagtcaa cggttgactg gggatcctta gctagtgagg cttggtatga tacaatcaca
    26521 agggattttg ttgcaggtga gtgtgtttgg acgggctttg attatctagg ggagcctact
    26581 ccttggaaca agattgactc aggcgcagct gatcagtggc cgtcgcccaa gcaatcctac
    26641 tttggtattt tagatactgc tggatttgct aaggatagct attatttcta ccaaagccaa
    26701 tggtcaaaag acaaaacgac acttcatatc ctgcccagct ggcaggaaaa agaccttcag
    26761 ctagatgatc agggcatggt ggaggttgtg gtttatagta atgctgctag tgtgagaata
    26821 ctttttgatg atggtcatgg gggccagatt gattatggca tcaagaccct gacaaggcat
    26881 gaaacaccag caggccattg ctaccagcta tatgagggtg acgatgcagc agaattacct
    26941 catcaaaacc tttacctgac atggaagctt ccttatcgct caggcagctt gagagctatt
    27001 gcttatgacg acaagggaca ggtgctcaca cagaccagcg gtcgttcctg tgtgagcagc
    27061 taccagcagc ctgctcagct ttcctggtcc tgctttgagc ctcctaaact gcttgcagag
    27121 cctgcgctac tttatcttga attgtctttg ttagatgcta atgagacctt ggtgctcagt
    27181 gctaatcctg tgattaagct tgaggttgag ggtcctggag cctgccttgc tctggataat
    27241 ggcgatcctc gtgaccatag gccctatact gccttgtcac gccgagcata tggtggcaag
    27301 ctattagcca ttattgctct tgatggtcgt gcgggtcagc ttagaataac agctagagcc
    27361 gcaggattcg tggaagccag ctatcagttg acggtttctg aagcagccgt taatgagaag
    27421 cttttagcct atcagcttga taaatacagc tttatcacta atgagacaaa taagcctagc
    27481 aagccctatg caaggtcaag aggatcagct gttgatagct taatgcctaa tcctgatagc
    27541 tgcttaaagc ggcaaggcca ttatctgcct gataattctg taatggtttt tagctataca
    27601 acagcattat caaggccact gacctttcag ccactgatca aaaggctgct aaagggcaat
    27661 gatatcattc taccagactg gctgcagcct agggcagctg ctggccagtt atttaccaag
    27721 gcttttccta ttgattggca gctaacagag gcagtttttt ctgaggagtc aagggttagt
    27781 gggcagaccc tttgttttgg agaggctttg gagcttgaag ctatccttaa gtcagataca
    27841 aaaggattaa ggatcaatca agagcttagc ttagttgcta aaaagaagcg gctgtttcag
    27901 agtgataccc agcttagcta ccgctatcaa tacgatacca tacaggccat tggtgccatt
    27961 agcctgacag gactaaagaa gcccttaagc tcgcttaggc ttgttttgga ctatcgcagc
    28021 agcaccaatg cgccatcaaa acagctgatc ctatcgcttg atcagataga acagccctgt
    28081 cactacatca tgctggaaga agtagttgat gtgctaagcc tggacctaac attagagcag
    28141 ccgatcagac aggcttttga cttagctagg cttcagctag gcctttggag catggttgag
    28201 gaggcttagg cttcaagctt atcggctcat actgtcaata ggattgagct gagacagtct
    28261 ttgaaaaata aggtataatg acagtaaatg cctagcaagc tttgctaggt tagcaaaaaa
    28321 taagcatcgc ctgatatgat gtaaaggagg aggtatttga tgctagagcg tttatcaggt
    28381 cagacacgat taacagcttt gctggcagca ccggcacgtc acagcctatc accgaaaatg
    28441 cacaatgcag cttatgctaa gctggggctg gattatgcct acctagcctt tgaggttggt
    28501 aatgctgagc tagctgctgc tgttcagggc atgcgtgcct tgggtatttg cggtgcaaat
    28561 gtgtccatgc caaataagca ggccattgtc ccattgcttg atgagctatc accggctgca
    28621 gccttagctg gagctgttaa tacggttgtt aataaagatg gcagaggtca tcttgttggt
    28681 catatcaccg atggcacagg tgctattcga gccttagcag aagaaggggt ctcgataaag
    28741 gatcagatca ttacgattgc cggtgcaggc ggtgcaggca cagccattgc tgttcaactg
    28801 ggacttgatg gcgccaagga gattcgacta tttaatcgga aaacagctac ctttaagcag
    28861 gccaagcagc tggttgctag aattaatacc caaacctcag ccctggcaag ccttcaggat
    28921 ttagcggatg atcgagcctt taggcggtct atttcagagt ctagcattta tattgacgcg
    28981 actggtgtag gcatgaagcc ttttgaggag catcgcctga ttactgatcc agctcttatt
    29041 cgcccagatc ttgtggtttt tgaccttgtt tatcacccgg cagaaacaaa gctcttagcc
    29101 tttgcgcgtg agcatggggc taaaaaagtg atgaatggcc taggcatgct cctttaccaa
    29161 ggagcagaag cctttaagct gatgacaggt gaagacatgc cggtagccta tatccgagag
    29221 cttttatgtc agaacaagga atgaacgcct gctgctcacg ccggtatagg aaaaagaaaa
    29281 aaaggttaat tgctcagctc tttgattggt cttgaggttt gtcggcattt tatttataat
    29341 aaaaagcacc aaaagcaaag gagcagccta tgatattgac acaatttgac cctgactacc
    29401 aagctatcat taaccctaag gaccttgtag cagaaataga tgactttcct aaaacagtag
    29461 tcacctgctt tgcaagagca acctttaata gggtacttaa tgcactgcca catcgactga
    29521 tagccacaac aagcgttgct aatcttgata ttccaatata cgaattagat gttaaagggc
    29581 ataagcttgg ctttttcaat tcctacgttg gagcagctgg ctgcgttggg gttttagagg
    29641 atatcattgc tatgggaatg aagcagctct tggtttttgg gacctgtgga gtcttagacg
    29701 ctactatcag tgaaaactct attattattc caactagtgc tattcgagac gaagggacca
    29761 gctaccacta tcagcctgct agtcatgaca ttgcagtgaa tcaagcttat ttaacaaggg
    29821 ctattgatgt tttagaacag cattcccaga cctataccct tggtaagacc tggacaacag
    29881 atggcattta tagagaaacc agagacaaga tgattcaacg aaagcaggaa ggggctattt
    29941 gtgttgacat ggaatgctct gcgattgctg ccctagcagc tttcagacag ctagagcatt
    30001 ttcagttttt ttattccgct gataatctag atgctgatga atgggacgca agaagcttag
    30061 ccaatgaagc agacctagaa gccaaggata acattgcctt tattgcctta gagttggcct
    30121 tacgattatt taaggataat taaaaaagca ccaagagcta tgaagtgcct ccaaaaggtt
    30181 agattaaggc tctaacgcct gggagatcag ttcagctcaa ggtgcttttt aggtgtcatg
    30241 cagacagctc acctctgcat gtcaatataa tgtttagagt agcctatgct tcttatacct
    30301 atgccttagc attcacctag ggacaaagca atgaagctta ggcctttcac cttactgtga
    30361 aaaaagtggt cttttctcat caaaagactc agtaaacaag aggctttgaa gcctttttgt
    30421 ttttcagaag cagcagtttt ttcactcgac taataagaca ggagaaaagc cttctcaggc
    30481 gatatctagc aggcttctta gccaatccag caggcgactg tcatgcttag caataggaaa
    30541 gcttacatag ccttttgtcg ttggcaaaat gaggacaata tgctgaccag aatttttctt
    30601 atctgttttt aaaacagtca tcaaggcttc ggctgtcatt gacttagcct caagtgtggt
    30661 aggtagctga taagcctcaa aggcagcctg taatgcctct aaatcctgtt ggctcaatag
    30721 ctgctgctgg acggccagct tggcctcaaa gaccatgcca atcgcaatag cctcaccatg
    30781 cctgtaaagc tcgtgatggc ataaggcttc aatcgcatgc cctagcgtat gcccgaaatt
    30841 taaggacatg cggagattgc cttcaaattc atccttttca accactcttt ttttatggca
    30901 aatcgcttga aaaatcattt gcctgagctg ctcttgattg cggtccttgg ggaaggctag
    30961 gagctgttga aagagcttgc gatcatgaat aaaaccaatt ttaatcattt cgctgatgcc
    31021 gcaggcaaat tctctttcag aaagcgtgtc taaaaacttg gctgacacga taatctggtt
    31081 tggagggtag atactgccta tcatattggt caagccctta aagtgaaccc caaccttacc
    31141 accaatgctg ctgtctacct gactaagtaa ggttgttgga atctgaacgt aggaaatccc
    31201 gcggtaaaag gttgccgcaa caaatccccc aagatctcca atcacccctc ctccaacagt
    31261 aacaatgacg tcctttttag aaaaattagc cctaatcagt cgatcgtaaa tccgactaac
    31321 ctcctctaga gacttagatt gcccccctgg agcagcaata tgaaggtaac tatcgtaatc
    31381 ctgttgaaaa cgtctaaata aaggctggta taaatcaaat accgtttgat cagtgataaa
    31441 taatagcttg acgtctcctt tttcagcaag aaattgattc agcggctgaa aaatatcgtc
    31501 tgtaaagata atcggatagt cattgatacg agacttaacc tgaagtgttt gtgtcatgcg
    31561 tctttctctc ctaagcacca ttagttcaaa tgactggacc tgtggctgct gttagttagc
    31621 tttcccaaag ctcttttcca agctgctcta gctgttgata atcaatctgc tgcgcggcat
    31681 ctgacaaggc aagatcaggt gtagggtgca cctccatcat aataccattg gcaccgatag
    31741 ccttagcggc cttagccgca ggcaatagta aatctcttct tcctgttgag tgagagacat
    31801 caacaatgat tggcagcttc accttttgct gaataatagg gactgccatg atgtctagca
    31861 tatttctagt ttccacatca tagccacgaa ccccacgctc gcataaaata atattttgct
    31921 tgccattttc ttgtaaataa gataaagcac ccaaatattc ctcaatggtt gccattagtc
    31981 ctcgtttaaa caagataggc ttgtcaatct ttgacaatac ctttaacagt tcaaaatttt
    32041 gcatatttcg agcgccaatc tgaataatat ctaaatagtc ataggcttcc tctagctgcc
    32101 tttcagacat aatctcacta acagccttca gcgaaaattc ctggcaaacc tcatgtagat
    32161 aggtaacccc tgtcagccct aagccctgaa aggagttaga agaggttcta ggcttatagg
    32221 ctccccctcg aaaatacctg tagcctaaag ccttggcact tgctgctgcc tgtctgattt
    32281 gctgataaga ttcaatggca cagggaccaa caataaagtt actcttttga cagcccttgt
    32341 ttaaaaaatc agctattata tcgtttccca tttatactct ttcctaatat gatattgaga
    32401 gaatgattcc ccaaaggtaa gatgacagct ctgtcttaga taatactgtg aataaggcat
    32461 gacagaacta ttcatagctt gggaaatcat accataatca agcttaaatt tcaagctaat
    32521 aaagagagtg accagctcgt tgacaaagga gaagcttttg agaatcctag ccctctaagg
    32581 tagagatttt atggctatta gagctgttga gaatgcttat tagctggaat aggcaagcat
    32641 ggtggggaag tgctgatgat tgagtatcat gatgaggcta gttatagctt ttattgtggg
    32701 agagtttagc ttttcaaata caaaaagaaa aggtttacct atatcgtttt tttggtgtat
    32761 atataatata tagaaagcaa actattttag aaacagaggt aatggtagat gttaaggtat
    32821 ttaaaagcga ttttatatct attggctccc agattagctt tttcagtaac aggtgtatta
    32881 tttcctgatg tttttgataa tttattcttg gtttataata ttttaatgac acttgctttt
    32941 tggcttgcga tttattctgt tgacctccca gaaaaatagt tgcgggactt gtttagtagt
    33001 tggttaacaa agggtagatg atcagttaaa ggtgaagcgt ctgagctatg ttggccatta
    33061 tgcgtacagc tggcaaaatg cttttgatcc aatcggttaa acctcaagct attctctttg
    33121 ggataacaaa taccccatct gtctcagaca aagaatggca acgcctaaat aggattaaca
    33181 tctgcaagtg ctcttgggac tgccaatgct cttagtagca taggtgattt ttcagcgcta
    33241 gagacttttc agcagatgag aaatagtcgc aataaacgaa gacaaaaaga cttggcttga
    33301 gctcgtattt ggccttaaaa tagtagtcag tcgagcttaa aaaaaagtca ttgcagctta
    33361 tgaaggttat cgtatcctta tttcaactga gctaggtaag ctagggagtt tcctttaggt
    33421 gtaacgatag aagcgatcaa ataattactt catttaaaga taaggattgt aataagcata
    33481 gaaaagagca gttacttgac ataactactc aatgtaaaac cgtttcaggc ggtggctttt
    33541 gttattagat aaaaaataat cgtcatcatt cggccaaagt tagaacggtt atgttttatg
    33601 ctcatctttg aagatgttat agcacaagcc aatagggaga ctaaagctta aaaagagttt
    33661 gagtagcttc aaaggctgct agctttttgg cctcctccat tttgttagct gttgatgaat
    33721 cgcccatagg caccaccacc cactcagaac gagcagccac ctgtcttaat ttttttactc
    33781 taccactgta gcatgccaca agaaaaaatc agaacactaa tgacatttta aaaaaaaaaa
    33841 aaaagacttg cacaccaaaa caagttatag tatcatagaa aggtagccgc tatagttaaa
    33901 tggtataata aagcaatggt aatgcttcgt tccgagttcg attctcggtg gtggcatctg
    33961 agtactgtcc taagtcttat taggacggtt tttttattgc taggtgaacc aatagtagtc
    34021 atctgtgaat cattaccata gtggcttctg ttcgcccaag catagcaaag ctgctgtcag
    34081 aatgaaccca gccaacaatg tcaatagaag cagcaccaga caagccttta gtcacccatg
    34141 ctttaaagat tttacggctg taatgttagt aactgttacc tgttttgttc aagttgtctg
    34201 tgacatcaaa tcacttgatg ctaccagtac tgtcaataca ttagctgtca cttggcagtt
    34261 gttctgacta ctactaaaaa tagcagctat cagcgttgca atcaaaaaag aatgcgaatc
    34321 aagctctcct gatcagctta actttttgaa agagtttgta cgggtcaagc atcagcaagt
    34381 cagactgcct tatttgtttt tatcataagc ttctaagaaa atagcacaat aagccaggct
    34441 gtggtataat ggtaaggatt aagtcagaaa gaggggggca gacatgtctt atgagcaaga
    34501 ctttttgaga gattttgaag actgggtgaa ggctcaaatt caggtcaacc agctagctat
    34561 ggcaacgagc cggcaaattg caaaggaaga taatgatcaa agagccagag atgcctttat
    34621 tcgttatgag agtaagctag atgcttatga gtttttatta ggaaaatttg ataattataa
    34681 taaaggtaaa gcttttcatg aggtgccaga cagcctattt ggtagccgtc attattagag
    34741 gaagggataa gcagtaatca tggcaagacg atacaatcgt aaaaaacaat acaagctaca
    34801 gcttaagcgt caaggactgc tcaaggcagt aatcaatcaa gtggagcaga ctgtggaaaa
    34861 ggtggttgat aagactaaag aagcagtgca taccgcttca caaatggtaa cagcatcaaa
    34921 gacagagact gctgatctac aggataagca gagcattgct gaaaaagcag ctcagcctaa
    34981 agcagatgta gcttctagta gcttggctga cagttctgag gtttcaagtg aaaaagaggc
    35041 ctcaaaggct agcagtgaag tcttatcacg cgatgctttt gcagagttgg ctgaggtttc
    35101 agagcttcgg gcagatattg ttacggtgct ttttgaggct ggtattaggt cagctgctgc
    35161 ttttagccaa tggacagagg cagagctttt ggcgcttaag ggaattggac cagcgactat
    35221 cagcaagcta aaggaaaatg gtgtcaactt taaaaagtag tctgattttt attgcttaat
    35281 aagtataaat ttgttagaat gttagcaatc agaggtatct tgagtttgtc tgttacagag
    35341 agcggtggtg ttgagaaatc cgcacagatg tcaagttatg tagctgaggc ttacaatgga
    35401 aaaatgataa agcagcagat taagtgtaat ctgaaacagt ggtggtaccg cggattatta
    35461 gtgaattcgt ccctgtctag tcgattgact aggcggggtt attttttgga ggacttgcta
    35521 tgattgagat aatgggttct gttgagaata atagattacc agatgtcaaa actagtcgtt
    35581 tgctgctgcg gcagcgtact ttagctgatg ttgaagcgat ttttgcttat gctagccgac
    35641 ctgaggttag ttacccagca ggctttccac ctgtgaaaac ccttgaagaa gaggagcatt
    35701 acatcgcaaa cacgatgcct aagcgctggc ttttgcaaca gctgccggca ggctatggca
    35761 ttgccctaaa gggtgacaat aggattattg ggtctgttga ttttaacaac cgtcacgcag
    35821 atgatgtctt tgaaatgggc tatctgctcc accctgatta ttggcatcag gggattatga
    35881 ctgaggcagc gagtgccctg ctagaggttg cctttactct gcttaagctt cataaggttg
    35941 aaatcagctg ttacgattac aatatgggga gtcgtcggat cgcagaaaag ctagacttca
    36001 ctcttgaggc gaccattcgt gatcgcaagg acgctaaagg caatcgctgc gcagacttgc
    36061 gctatggact gttgaaaaga gaatgggaga ggcagtgtag ataaggagta gactctctaa
    36121 aatatgcgtt aatctgtcaa aagcatttca taagaagtcc tcaaactcaa agcgcttatg
    36181 actaccaaaa ctggttagcg cttcgccaac cagtgtcatc agtttctggt agtctgcctt
    36241 gagcagcaag tgttatgtta agtgaggtga gaagaggtaa gagagatcgg aaagaggttt
    36301 ggtatgaata ttatcttaat tggagcacag gcgtctggta agatgacaat tggacaggaa
    36361 ttagaaaaac tgactgacct gactttattt cataatcatg aatcgattga ttttgtgact
    36421 aagtttatac caatgtcatc ggaagctaga gaactaattg atgagctacg attgctattt
    36481 tttaaaacat ttgcaaaacg tcagcaatca attattttta ctgttgtcat tgattttaat
    36541 gcacctgaag atatagcgtt tttggaaaca ctacagagtg tgtttcatga tttcgacaga
    36601 gaggttttat tcgttgaatt agaaatagat ttaaaagaac gcttaaggcg aaataaaact
    36661 gaaaatcgac tttaccacaa accgataaag cgtcatttgg agtggtctga gaaagatatt
    36721 ttggatactg ctaaatttgc taactttaac cctgcaaagg taccagaaaa tcttaaatat
    36781 tattgtaaaa tcaataatac gagtctttct gctcaagaaa cagcgcagtt tatcgtccaa
    36841 aaaatgaaag agttagaagt aagctagaaa ggacaccata tgtcaaaaga actttcaccc
    36901 aaatacaatc cagctgaggt tgaggctggg cgttatcaag cttggctgga ccaagatgtt
    36961 ttcaagccat caggcgacaa gaaggctaag ccgtatgcta tcgtgattcc accgccaaac
    37021 gttacaggga agctgcacct tggtcatgct tgggacacga cccttcaaga tattattatt
    37081 cgtcaaaagc gcatgcaggg ctttgatact ctctggttgc ctggtatgga tcatgcaggt
    37141 atcgccactc aggctaaggt cgaggagcgc ttgcgcgagc aggggatttc ccgttacgat
    37201 ctcggtcgtg acaagttctt agacaaggtt tgggaatgga aggacgagta tgcagcaacc
    37261 atcaaggagc agtggggtaa gcttgggctt tcactagact atgcgcgaga tcgcttcact
    37321 cttgatgagg ggctctcaaa ggctgttcgc aaggtttttg ttgagcttta caagaaaggc
    37381 tggatttacc gcggtgagtt catcatcaac tgggactcgg cagctaggac agctctttca
    37441 gatatcgagg ttatccataa ggacgttgag ggtgccttct accacatgaa ctatatgcta
    37501 gaagatggtt cgcgcgccct tcaagtagca accacacgtc ctgaaaccat gtttggagat
    37561 gtggctgtcg ctgtcaatcc agaagatcct cgttacaagg acttgattgg tcaacatgtt
    37621 gttctgccaa tcgtgaataa gctgatccca atcgttggag acgagcatgc ggatccggca
    37681 ttcggaacag gggttgttaa aatcacacca gcccatgacc cgaacgactt tgaggttggt
    37741 gggcgtcata atctcccaca ggttaatgtc atgaatgatg atggtaccat gaatgagctt
    37801 gcaggtgaat ttgcaggtat ggatcgattt gaagctcgta aggctgttgt ggctaagcta
    37861 gaagaaatcg gtgcccttgt tgagattgaa aagcgtgttc attcagtagg tcattcagag
    37921 cgtacaggtg ttgtggttga gcctcgcttg tcaacacagt ggttcgtgaa gatggaccaa
    37981 ttggctaaaa atgctattgc caaccaagac acagatgaca aggttgactt ctacccacca
    38041 cgcttcaacg ataccttctt gcaatggatg gaaaatgtcc acgactgggt aatctctcgt
    38101 cagctttggt ggggacatca gatccctgca tggtacaacg aagcaggtga catgtatgtt
    38161 ggtgaggaag cgccagcagg tgatggctgg aagcaggacg aggatgtcct tgacacctgg
    38221 ttcagctctg cgctttggcc attttcaact atgggctggc ctgatgtaga ctcagaagat
    38281 ttccaacgtt acttcccaac gtcaacattg gtaacaggtt acgacatcat cttcttctgg
    38341 gtgtctcgta tgattttcca atcgcttgaa tttactgggc gtaagccttt ctctaacgtt
    38401 cttattcatg gtctgattcg tgacgaagag ggacgcaaga tgtctaagtc gcttggaaat
    38461 ggcattgatc caatggacgt tatcgaaaaa tatggtgcag atagcctacg ctggttccta
    38521 tcaaatggct cagcccctgg tcaggacgtg cgcttctcct atgaaaaaat ggatgcgtcc
    38581 tggaatttca ttaacaagat ttggaacatt tcacgttaca ttctcatgaa taatgagggc
    38641 ttgacacttg agcaagcaag tgcaaatgtt gagcaagttg cgtctggcgc tgctggaaac
    38701 gtgacagact gttggatcct ccacaatctc aatgaaacaa tcggtaaggt cacagagaac
    38761 tttgataagt ttgagttcgg tgtggcaggt catatcctct acaattttat ctgggaagaa
    38821 tttgccaact ggtatgtgga gctgaccaag gaggttctgt acagcgacaa cgaagacgag
    38881 aaggttatca ctcgctctgt tctcctctac acgctggata aaatcctgcg tctccttcac
    38941 ccaatcatgc cgtttgtgac ggaagaaatc tttggtcaat acgctgaagg ttctatcgtg
    39001 acagcggact atccaacggt tgatcctgct tttgaaaatg aagctgcgca caaaggcgtg
    39061 gaaagtttga aggacttgat tcgtacggtg cgaaatgcgc gtgcggaggt taatgtagca
    39121 ccaagtaaac caatcactat ccttgtcaaa acaagcgata gcgacctgga agccttcttc
    39181 aacagcaatg tcaactacat caaacgcttc acaaatccag agaggcttaa gattgcttca
    39241 agcattgtga ctcctgagtt ggccatgtcg gctgttatta caggtgcaga aatcttcctt
    39301 cccctagctg atctgctcaa tgtcacagaa gaattagctc gccttgaaaa agaattagct
    39361 aagtggcaaa aagagcttga cctggtcagt aaaaagctca gcaatgaacg cttcgttgct
    39421 aatgccaagc cagaagtcgt tcaaaaagaa cgcgacaaac aggctgatta ccaagctaaa
    39481 tacgatgcaa ccgtagagcg catcaaggaa atggagaagt tagtaaggta ggatagtgat
    39541 catctaagag ccaattggct ctttttttga tatactgtca aggagtaatc atcacaatta
    39601 tctatataag tcaaaggagt gtctcatgaa aaaaagagtc attggttggt taggtgtgct
    39661 ggtaataggg cttatgcttg gtctgatatg gtggaaatgg ttagtggcag atcggccact
    39721 aacccaagca ggtcaaggaa gtcatgacca cagcagcgac aaaggcctca gtgccgcata
    39781 aggaaaaaat ggaatcaaaa gagcctgaga catcacatca gccagaagcc tatcctgatc
    39841 ttgctagcta tcaggaattg gctgttcatg tgtcgattgc agaccaagtc atgaccatta
    39901 taggagatgg taaggttatt tttaagacca gcgtgtcaac aggagcaaag gaaagtccaa
    39961 caccgacagg gacctttgtc attgagcctg agcgaggaga ctttttcttc aatcaggcat
    40021 cagaagaggg agcttattat tgggtgtcct ttaaggacca tgggatttat ctgtttcaca
    40081 gcctaccaac agaccaatat ggcaatgaga ttccagagga ggcagagaga ctgggacagc
    40141 cagcctcaca tggctgtgtc cgcatgagca gagcagacgc caaatggttt tatgacaata
    40201 tcccagaagg catcagcgtc acaatagaat agccctaatc tccctcagaa tagcctgagc
    40261 agatagagga agagcctgtt aatattagca ggcttttaaa gctccttaaa aggctgcaaa
    40321 aaggaacgaa aaaagacctg aaacaggtcc attgatctaa gagaagacaa gtaactagcc
    40381 ttctagcaaa gtgttttaaa aatgcgttag tttagtagct tcgtgataat acaattaata
    40441 atatttattt aaaaaaactg taaatttcga ccactgttcc tggatttttt catttaaacg
    40501 tttatgccat gacttatgag cattctctct aatttctttt aggtatatat tttctactac
    40561 ccttttttga ctatgttctc gctctttttt tatttgctgt cttaaattct cttgtttttt
    40621 ctgttcttct aactcttttt gagctttctt ctgttcttgc tctattatgt cttgaggttt
    40681 agattctcct acaatccata tttctgaacc taagacaaaa ccatctgagg taatatgaac
    40741 tctaaattta tcaccattag aagcaatttt attatatgga acatatgttt cttctttgga
    40801 atttgttttt tgtgttctcg ctgattctaa agagaacaca atttttccat cccactttgc
    40861 aattggatag taccggttat ttgttaagtc accattgctt tttttttgga cttgtactaa
    40921 ttcagtttcc ttatcatctt cttcgacttt aaatattcta atcaaagatc ctggactagt
    40981 ttttactact atttctttgt cattattttt gattggttta acgccaaagt ctcgagcgtt
    41041 ttcccaatct cttctaaatc ctattacctt ttggtcacca atttgtggtg cttctgtata
    41101 atcatcataa ccataatagc cttgccctaa aactggagaa ttttcataat cactatttgc
    41161 acttacttcg ttgaaacata ttaaacttag taaaggtaaa ttaacgatta aactcatcac
    41221 taacttcttc ttcatttttt cttcctaacc tccattactt atgtttattt aataa
//
LOCUS       DARYXW010000007        39096 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.007, whole genome shotgun sequence.
ACCESSION   DARYXW010000007 DARYXW010000000
VERSION     DARYXW010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39096)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39096)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39096
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.007"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(93..464)
                     /locus_tag="TV191_000292"
     CDS             complement(93..464)
                     /locus_tag="TV191_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1506842.1"
                     /translation="MKLRRKTRLTKIGAPMTVNIGKSHKVKLYPGESIDIDLPDAEDY
                     LTIKHSRQAKKIVTNQDQVTITDNPINLILFWSGVVLVLGSHLVLSFDSSWLYWLTII
                     GLSSIIVSYLVPRFKWVVTQS"
     gene            683..1321
                     /locus_tag="TV191_000293"
     CDS             683..1321
                     /locus_tag="TV191_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEL1506843.1"
                     /translation="MVKGIIFDMDGVLFDTEPFYLKRREAFLTSKGIRIDHLSPEDFI
                     GGNLQQIWDKVLAGQANADEARDIAVAYEAYKLCHKPPYQELMFKGVKSCLKALKGQG
                     LKLALASNSSRCDILLALESSHIKAYFDLTLAREDVTAGKPNPEIYNKVAQALGLAKA
                     EFVVVEDSQKGIAAAKAAGLKVLAIKDKRYGIDQGQADKRIDSLRQLCELLR"
     gene            1517..2053
                     /locus_tag="TV191_000294"
     CDS             1517..2053
                     /locus_tag="TV191_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1506844.1"
                     /translation="MLSLLIGGLMAVKLLTERLIIQELNETYFEPYHKAFTEEITAFQ
                     WPDPFKDIAAAKETLASFIAEMKKGNMLELVILNKANDFVGSLEVFSLDSETPELGIW
                     LKKSSQGLGYGYEALRAIVDYLKGKNKYRYFNYEVDVRNTGNIKLVEKFNVVTSTYQE
                     CETASKKRLCLQVYHILN"
     gene            2916..3320
                     /locus_tag="TV191_000295"
     CDS             2916..3320
                     /locus_tag="TV191_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEL1506845.1"
                     /translation="MTEIPKDLKLNTISVFEHYHIDVFEAGHVLLSTEIHASALNYYG
                     NAHGGFLFTLCDQVGGLVAKSIGLEAVTLQANVNYLKPGHLGDRLVVEGSLVHRGRTT
                     QLIEVTIKNQDDRLLTRVSLTMFVTSKKRSSD"
     gene            complement(3376..4860)
                     /locus_tag="TV191_000296"
     CDS             complement(3376..4860)
                     /locus_tag="TV191_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEL1506846.1"
                     /translation="MKNIAFDSNKYLSLQRNHILERIKQFDGKLYMEFGGKILEDFHA
                     ARVLPGYEPDNKIKLLKELKDQVEIVITINANNIEHSKTRGDLGISYDQEVLRLIDTF
                     NALDIYVGSVVITQYNHQAAADHFQKQLAKNGITSYRHYPIKGYPTDINHIISPDGMG
                     RNDYIKTSRNLIVVTAPGPGSGKLATCISQLYHDQLKGVTSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLEAYGKTAVNYNRDIEVFPVLNRTFERILSQSPYA
                     SPTDMGVNMVGFSIVNEEAAIEASRQEIIRRYYQTLVDFKAERVTEAAVKKLELLMND
                     IGVTPKDRQVTLIARQKAEITGQPALALQLPNGQVVTGKTSDLFGPTAAVIINAIKTL
                     AHISKETHLIEPEYVKPIQGLKINHLGSHNPRLHANEILMALAITAMNNNQADLAMKE
                     LGNLKGSEAHSTVILTNEDKHVLRQLGINVTFDPVYQHHKLYRS"
     gene            5219..6442
                     /locus_tag="TV191_000297"
     CDS             5219..6442
                     /locus_tag="TV191_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1506847.1"
                     /translation="MSALSLDKNNKRALWAAIAASGTDDLNVMFLAFSMSSIISDLGV
                     SSTQGGWIATITNLGMLFGGLLFGLLADRHHKFKVFKWTILIFSVATGLIYFTKTIEF
                     LYLMRFIAGIGVGGEYGVAIAIMAGLVPAEKMGRVSSLNGIAGQVGSIVSALLAGWLA
                     PALGWRGLFLFGLAPILLVIWMMVAIDDDKIIDNHVNVSEEASQPVKISELFKTPALT
                     GQTLALMVMTTVQIAGYFGMMNWLPTIIQASLHISVKDSSLWMVSTIVGMCLGMLTFG
                     HLLDTFGPRLVYSIFLLLSSVCVYLFQFANSMSTMLIGGAIVGFFVNGMFAGYGAMIT
                     RLYPHHIRSTANNLILNVGRAVGGFSSVIIGKILDVSSVSMVMLFLALLYLVSFVALW
                     TIKNLKAERYQALTK"
     gene            complement(6532..6891)
                     /locus_tag="TV191_000298"
     CDS             complement(6532..6891)
                     /locus_tag="TV191_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase family protein"
                     /protein_id="HEL1506848.1"
                     /translation="MSIYSQLYETKSKHSAQAMGSGGLEVLATPALVAFMEHAAFTFL
                     QSQLKDKQTTVGSEIAIQHLAASKIGQAVTIVITALKEEGRKYDFRIEAFANHKLIGR
                     ACHTRVRVDQDAFLEKL"
     gene            7056..7769
                     /locus_tag="TV191_000299"
     CDS             7056..7769
                     /locus_tag="TV191_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEL1506849.1"
                     /translation="MRLDKFLVDAGLGSRSQVKLLLKKKQVSVNGVSQTSPKYQVNEM
                     TDEVSYQGQRLNYEAFVYYMLNKPKGVISATEDSSHKTVLDLLDDTARQKAVFPVGRL
                     DKDTHGLLLVTNDGKLAHALLSPKKHVAKQYLAVVDGMMTQEDVKHFAQGITLKDHQC
                     MPAHLDILEINESLKTSLVKITIEEGKFHQVKRMVAACGKTVSDLQRISMGPLQLDSA
                     LAPGAYRRLTAAELEALKA"
     gene            complement(7848..8675)
                     /locus_tag="TV191_000300"
     CDS             complement(7848..8675)
                     /locus_tag="TV191_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018164168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEL1506850.1"
                     /translation="MVLPHFDDYLEKYANLLIKKGVNIQKGHTLLISIAVEQHKLARL
                     LTKKAYEAGAAEVLVDYNDDQITREKLLKADEDRLLQVPDYVVEQSHYLLDQKASRLV
                     IRSANPNVFADIDSDRLAGATRATAIALEKQRAATQANKVSWNLAAAAGPEWAAMVFP
                     NLTSEEEQVDALWDAIFKMNRIYETDPVKAWDQHQERLEKKARLLNDYQFDSLHYRAP
                     GTDLRLGMPEQHIWEAAGLNRSTAHADFMIGSEQMDIDGITKDGEVIPIFRGGEWAI"
     gene            8936..9064
                     /locus_tag="TV191_000301"
     CDS             8936..9064
                     /locus_tag="TV191_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEL1506851.1"
                     /translation="MAFGENGPRKKTAFEKLTTVVVIVMVLVTVGGLIAGALSVLM"
     gene            9118..10431
                     /gene="obgE"
                     /locus_tag="TV191_000302"
     CDS             9118..10431
                     /gene="obgE"
                     /locus_tag="TV191_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEL1506852.1"
                     /translation="MSMFLDTAKVSVQAGRGGDGMVAFRREKYVPNGGPWGGDGGKGG
                     SVIFKVDEGLRTLIDFRYNRKFKAKSGEKGMTKGMHGRGSEDLIISVPQGTTVRDAET
                     GKVLTDLVEHGQEFVVAKGGRGGRGNIRFATPRNPAPEIAENGEPGEERQLELELKIL
                     ADVGLVGFPSVGKSTLLSVVSSAKPKIGAYHFTTIVPNLGMVRTKSGESFAMADLPGL
                     IKGASQGVGLGTQFLRHIERTRVILHVIDMSAAEGRDPYEDYVAINKELEAYNLRLME
                     RPQIIVANKMDMPEAKEQLQRFKEQLAAQYDDFEELPIIFPISSLAHQGLDSLLEATA
                     ELLAKTDDFLLYDEADLAEDEAYYGFAAEEKAFEISRADDAAWVLSGEKLERLFVMTN
                     LERDESIMKFARQLRGMGVDEALRERGAKDGDIVRIGKFEFEFVD"
     gene            10552..10710
                     /locus_tag="TV191_000303"
     CDS             10552..10710
                     /locus_tag="TV191_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1506853.1"
                     /translation="MGDKPISFKDKDGNFVSAADVWNAEKLEELFNLLNPNRRLRLER
                     DKLKKDEA"
     gene            complement(10763..11467)
                     /locus_tag="TV191_000304"
     CDS             complement(10763..11467)
                     /locus_tag="TV191_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEL1506854.1"
                     /translation="MAYLNYFTKTEWTLWLTSISAILLSAFFFGEQAPLALIASLIGV
                     TALIFSAKANPIGQSLAIIFSLIYAYLSLLNSYYGELITYLFMTLPMAILSLFTWLSH
                     PFEDQTSQVTISRLTTADRLRLVVLTILVTSLFYAILAYLKTAYLPVSTLSIATSFSA
                     AYLSYKRSPYFALAYALNDLVLILLWLYAAQANTSQYAVVICFAAFLVNDIYTFFNWL
                     HLQHHQEKKHQKRTKP"
     gene            11802..13202
                     /locus_tag="TV191_000305"
     CDS             11802..13202
                     /locus_tag="TV191_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEL1506855.1"
                     /translation="MKQSKRRYQFPEGFLWGSSTSGPQSEGTVSGDGKGPSNWDYWFS
                     LEPDKFHHQIGPEVTSTFYTNYKSDIALLKETGHTAFRTSIQWSRLIPEGVGQVNPKA
                     VAFYREVFQEIMAQDIKLIVNLYHFDLPYALQGKRGWEAKETVWAYETYAKTCFELFG
                     DLVDTWITFNEPIVPVECGYLGHYHYPCKVDAKAAVQVAYHTQLASSLAIKACHELYP
                     KHRISIVLNVTPAYPRSDQPEDVKAARIAELFQTKSFLDPSVLGVYPEELVVLLEAAD
                     LLPQYSADELAIIKNNPVDFLGVNYYQPLRVQAPSKTRQDGEPITLASYFEPYDMPGK
                     KVNPHRGWEIYEQGLYDIALNLKEHYGNIDWLVTENGMGVEGEEAFLVDGQIQDDYRI
                     AFIEDHLIQLHRALEEGANCKGYLLWTFIDCWSWLNAYKNRYGLVALDLETQKRTLKK
                     SGHWFKTLSQTNGFDK"
     gene            13212..14306
                     /locus_tag="TV191_000306"
     CDS             13212..14306
                     /locus_tag="TV191_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HEL1506856.1"
                     /translation="MVTLGFSLYPERHGFAKSKAYIDLLHCYGAKRLFMSLLQLAPND
                     PKTFKFYADLIAYANCLGIRVIADVSPAFIKQAGWSDQVIEEAHAFGLAGLRLDEALP
                     LEDIVRLTKNSFGLKIELNMSTDKSLLTALLKAAPDRSNLIGCHNFYPHAFTGLSLEH
                     FKEMSHFYHEHGIATAAFITAQSAKEGPWPLSEGLPTVEAHRQLPIDVQVELMKATGT
                     IDTVILSNQFITEDELVQCRQALDRSVMSIKVKPLVDLTDIEEKIICYPHCYRGDVSD
                     YVIRSTMPREVYAQEAIAPREQPKQVKRGSIIIDNDRYNRYKGELQIALKAFTLSSKA
                     NVVANIKEDYLSLLDELKPWQEFSLVIETD"
     gene            14412..16406
                     /locus_tag="TV191_000307"
     CDS             14412..16406
                     /locus_tag="TV191_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEL1506857.1"
                     /translation="MLSKKEMAIVAFLISQKGQFVSSATLAKAIGMSDRTVRKYLKEL
                     ISSLPSKGAHIISKQGQGYCLEIDHSMAFEIFWQESLASKKRLADVTQVEETVDREHY
                     LLNKFFFEEPVWDFEELCQELYISRTTLNHVLAVIRDRIRPYQLQLDVSHQRVQVTGK
                     EEAIRHFIMDYFFATSFDDSMYAIVDNTFLDHIKFADITIIVLDECRDAKLKLSDFVM
                     HNLVLHIALMVQRIRSGYPLAFFSIPAAIRQSDEYQVALRILYRVEEVMGIRFPKEEA
                     NYIALHLKVKHSVDGSPQDNKADDLLRSHLKAGIVKASQLTGMSLEADSSLLQGLLAH
                     MKPLATRLENHIQLTNPLTEEIKSKYPEAFALTKQAFENIPELQAYDLSDDEWAYISL
                     HIMAAIERYSNRHKLRVLVVCATGYGSAMMLKNRLEKEFEGRFQIVDVISYYEITQER
                     LQTVDVIISSISLANVMFLTPVITVSVFLSDQDIKAIRQFIGEQEGIRREAASSSQMS
                     LEKAEQILKGVFSPKRFLYVKEKLSKKALLLKMIACLDEAMDEAFVEAFYHQIVLREN
                     YSSIVFGEVLAFPHPANPMTYSEQVVVAVCQEPIDWDESHRAVHFIFLLSPSKGRNSY
                     LKYISPSLVSFVNQAELQQALLEEPSYAQFITLFTPLITE"
     gene            16420..16737
                     /locus_tag="TV191_000308"
     CDS             16420..16737
                     /locus_tag="TV191_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1506858.1"
                     /translation="MKTIMLVCNAGMSTSMLVTKMQKAAQARGIEVEIWAVPVSEADN
                     EVAAKTIDVLMLGPQVKFLLKDFKTKFEPAIKVDVINMADYGLMNGDKVLETALTMME
                     EEV"
     gene            16734..17069
                     /locus_tag="TV191_000309"
     CDS             16734..17069
                     /locus_tag="TV191_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEL1506859.1"
                     /translation="MTQSSNLEAIMGLIMYGGEAKGKAVEAIHAARDGQFEKAQHLLQ
                     EATHSLNVAHRSQTNLLSQEAAGDQVDLSLLLVHGQDHMMTALAFIDLAKELVAVYDK
                     ISRIQRGEL"
     gene            17069..17503
                     /locus_tag="TV191_000310"
     CDS             17069..17503
                     /locus_tag="TV191_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HEL1506860.1"
                     /translation="MMITAEGDVSVTQCFKAILSSLQEDYHENTLRRLPPAELKAGLS
                     YIKHYGKSKEHNVRVLITALEAPHLYAACFSSNHGLKTLSYRLEALGEKRTKITYCYD
                     YQPLDVFQKANQLIIGKLFKKSFKRQSQAQLAALIQYAKQLS"
     gene            17578..18957
                     /locus_tag="TV191_000311"
     CDS             17578..18957
                     /locus_tag="TV191_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL1506861.1"
                     /translation="MSHFSDKFMEISGKMGSQRHLVAIRDSFISLMPITMAGSVAVLL
                     NVFLRDIPNNMGWTGFAAAMQPIIDINGYVYFGTIGIMALFFAFAFGYHLALMHKVNP
                     LAGGLISFASFVATLPQSLTISTPLEGASASLLAGLKDMGLSVVTANGARVLETSQWG
                     AIALKYAGATGLFTALIIGFLSSFVYATLTKRNLTIKLPDNVPPAVNKAFAAIIPGTV
                     AIYVSAIVAYLIFALTGSSLSDMISTYIQLPLLGLSQGLGSVILLTFLVQLLWFFGLH
                     GHNVLAPVLDGVYLVALTENTAAYNTSQSVANLPYLWTRGSFDAYAQMGGSGVTLALI
                     IAIFIFSKREEHKTIAKLSAPMGVFNINEPITFGMPIVLNPTFAIPWLIVPPICASIA
                     YAATAIGLIPPVFLPVPWITPVGLYAYLATGGSVMAGLVSLFNLFVAFLIWAPFVMSA
                     NKEKASDLS"
     gene            18954..19106
                     /locus_tag="TV191_000312"
     CDS             18954..19106
                     /locus_tag="TV191_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1506862.1"
                     /translation="MTAKNGASFLMAIGFFLIAISPMVGNKYLHIVTGLAFVGLGYYL
                     TKRKRP"
     gene            complement(19263..20003)
                     /locus_tag="TV191_000313"
     CDS             complement(19263..20003)
                     /locus_tag="TV191_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003107174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1506863.1"
                     /translation="MAELKIDVQDLHKSYGQNEVLKGINAKFYEGDVVCIIGPSGSGK
                     STFLRTLNLLESITSGKVVVDGFELSDPNTNIDKARENIGMVFQHFNLFPHMTVLDNI
                     TFAPVELGKVSKEAAKEKGLALLEKVGLADKADAFPGSLSGGQKQRVAIARSLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKDLAEQGMTMLIVTHEMGFARQVANRVIFTDGGQF
                     LEDGTPEEIFDHPKHPRLIEFLDKVLNV"
     gene            complement(20003..22168)
                     /locus_tag="TV191_000314"
     CDS             complement(20003..22168)
                     /locus_tag="TV191_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEL1506864.1"
                     /translation="MKNTLKAWMLAMLSVVLMTAGIASAETIDIVSDTAYAPFEFKDS
                     DQVYKGIDVDIINEVAKRKGWNINMTFPGFDAAVNAIQSGQADALMAGTTITAARQKV
                     FHFSDPYYDTKIVIATRKANPIKKYSELKGKTVGVKNGTAAQAFLDKYKKSYGYTVKT
                     FDTGDLMYNSLATGSIDAVMDDEPVIQYAINQKQDLAINMKGEAIGSFGFAVKKGSGY
                     DYLIDDFNEALGAMKADGTYQAIMTKWLGSNDKVTAGKATGDASAKATPLKPVYKIVA
                     DSSFAPFEFQIGSGEYVGIDMDLIKAIAKQQGFTIEISNPGFDAALNAVQAGQADAVI
                     AGMSITPARREIFDFSDSYYTSNIRLGVKSGSSIKSYKDLKGKIVGAKKGTASYDFLE
                     SNKDIYGYRLKAFDEASSMYDSLNSGSIDGLMDDEAILRYAIQRGHKLDIPIKGEPSG
                     EYGFAVKKGANPELIEMFNNGLAALKASGKYDAIISRYLDSEASVKTADESTIYGLLA
                     NNYKQLLAGLGTTLGLTLISFAIALVIGIVFGMMAVSPSKNLRMASTIFVDVVRGIPL
                     MIVAAFIFWGVPNLIESMTGHQSPINDFVAATIALSLNGGAYIAEIVRGGIEAVPAGQ
                     MEASRSLGLSYHTTMRRIILPQAIKLMLPNFINQFVISLKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFRMYAILAVIYLIMITLLTRLAKRLEKRLN"
     gene            22360..24351
                     /gene="uvrB"
                     /locus_tag="TV191_000315"
     CDS             22360..24351
                     /gene="uvrB"
                     /locus_tag="TV191_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEL1506865.1"
                     /translation="MIDKRDFKAFKLVSKYAPSGDQPQAIETLVDNIEGGEKAQILLG
                     ATGTGKTYTMSQVISKVNKPTLVVAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYA
                     DSAVSLRPGQEISRDQLLNALVDIQFERNDIDFQRGRFRVRGDVVEVFPASRDEHAFR
                     IEFFGDEIDRIREIESLTGKVLGDADHLVLFPATHFVTNDEHMEQSISKIQAELADQL
                     KLFEAEGKLLEAQRLRQRTEYDIEMLREMGYTNGVENYSRHMDGRSAGEPPYTLLDFF
                     PDDFLIMIDESHMTMGQIKGMYNGDKARKQMLVDYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYEMEQTDTIVEQIIRPTGLLDPEVEVRPSMGQMDDLLGEINLRVERG
                     ERTFITTLTKKMAEDLTDYLKEMGVKVKYMHSDIKTLERTEIIRDLRLGVFDVLIGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNADGHVIMYADRMTDSMQ
                     RAIDETARRRAIQMAYNEEHGIIPQTIKKDIRDLISISRAVEAKATEAETNYESMTRS
                     ERQEAIKQLQKNMQEAAELLDFELAAQLRDLILELKAMD"
     gene            24690..24833
                     /locus_tag="TV191_000316"
     CDS             24690..24833
                     /locus_tag="TV191_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEL1506866.1"
                     /translation="MLKNKSRLRAIFVFVGKIALFYVILMLLVYFFGYLGHGQSNFIY
                     NEF"
     gene            24845..26383
                     /gene="dltA"
                     /locus_tag="TV191_000317"
     CDS             24845..26383
                     /gene="dltA"
                     /locus_tag="TV191_000317"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEL1506867.1"
                     /translation="MVNDMIETIEYFAQAQPDFPVYDCLGERRSYGQLKEDSDSIAAL
                     IESLKLGEKSPVLVFGAQSYDMLASFVALTKTGHAYIPVDVHSAPERVLSIIEIAQPS
                     LIIAIEELPVSIDAIRVVSLAEIEAAKAAKAAFTMTSPVKGDDNYYIIFTSGTTGQPK
                     GVQISHANLLSFTNWMIEDAEFAIPERPQMLAQPPYSFDLSVMYWAPTLALGGTLFAL
                     PKEMVSDFKRLFSTIAELPIGIWTSTPSFADMAMLNDDFCQEKMPRLTHFYFDGEELT
                     VSTARKLFERFPDARIINAYGPTEATVALSAISITKDMIETYTRLPIGYPKPDSPTYI
                     IDEAGNALEPGQQGEIIVTGPAVSKGYLNNPEKTAEAFFTFNGMPAYHTGDLGSFTED
                     NVLLYGGRLDFQIKYAGYRIELEDVSQQLNQSPLVESAVAVPRYNKEHKVQNLLAYVV
                     LKDGVREQFARDLDITKAIKASVKDHMMAYMMPSKFIYREKLPLTPNGKIDIKFLINE
                     VNHQ"
     gene            26380..27627
                     /gene="dltB"
                     /locus_tag="TV191_000318"
     CDS             26380..27627
                     /gene="dltB"
                     /locus_tag="TV191_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEL1506868.1"
                     /translation="MTTLFHHIPYMEPYGNPIYFVYLIIAFLPVIIGIFKQRRFSTYE
                     SFVSLIFILLMFGGEHYQQLLAFLAYLIWQTISVLAYKHYRQKANAAWVFYLSILASL
                     FPLICVKVSLSLTRSFFSFLGISYLTFKSVGMIIEMRDGVLTDFSLKDFLRFMIFFPT
                     FSSGPIDRFRRFQEAYTKLPSRDVYLDMLNKAVMYLMLGFLYKHIISYCLGGLLLPLA
                     ENKALTVGGYFNKETIYVMYLYGLNLFFDFAGYSMFAIGLSYLLGIKTPENFNKPFLS
                     PNLKEFWNRWHMSLSFWFRDFVFMRLVHLLIKHKTFKNRNVTSGFAYLINMLVMGLWH
                     GLTWYYIAYGLFHGIGLIVNDAWLRKKKEINRRRKKQGLKPLFEGKVFHALSIVVTFH
                     VVLFSLLLFSGFLNELWFSRPLR"
     gene            27645..27884
                     /gene="dltC"
                     /locus_tag="TV191_000319"
     CDS             27645..27884
                     /gene="dltC"
                     /locus_tag="TV191_000319"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEL1506869.1"
                     /translation="MSTKETVIDLFDRLFMEDVSDMMDEDLFDAGVLDSLGTVELIVE
                     IESIFNIKVPISEFGREDWNTANKIIQGIEELQHA"
     gene            27877..29130
                     /gene="dltD"
                     /locus_tag="TV191_000320"
     CDS             27877..29130
                     /gene="dltD"
                     /locus_tag="TV191_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEL1506870.1"
                     /translation="MLKRLWLILGPLIIAFGLVCLTIFSFPTKLSYSLRQEKSNAVAI
                     NDSSFKNGLIKRQALSDPNYCFVPFFGSSEWSRMDSMHPSVLAERYKRSYRPFLIGKR
                     GSASLSQYYGMQQISQEITGKKAVFVVSPQWFTPQGIDPGAVQLYLSNSQVIDFLLKA
                     KASHKESQFAAKRMLDINPGVAKSELLRKISQGKALSRWDIRLLKWQQELSLREESLF
                     SFLGRSTNYEDRILPRVKGLPKTFSYERLSELAARRAKEGTSNNRFGIKNAFYSKRIA
                     PQFPLYKNFQCRNNYTVSPEYNDFQLVLSEFAKRKTEVLFVITPVNQAWANYTGLNQR
                     RYQKAVRKIKHQLTSQGFTRIADFSRNGGDKYFMEDTIHLGWNGWLAFDKEVVPFLED
                     QTPPSEYQLDPYFLSKDWADRTAGF"
     gene            29164..30138
                     /locus_tag="TV191_000321"
     CDS             29164..30138
                     /locus_tag="TV191_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEL1506871.1"
                     /translation="MLMSIIVILLILAIAVLVIEYGQKRSFSSWLLEKMFDYRKYKLS
                     KKADDYEGIETQRRRRIPYHLDNPEAVLGIPTTEYTIDGMQVFVINDQDSQDQPVIYY
                     LYGSVYLRRPETFHFKTIKHLIHLTNAKLVFPNFEKAPYVTYKEIYPKLAKTYQELCL
                     ANGAAKVSIIGDSSGGGMALALAQYLRDTQTAPQPKQLILLSPWLDVSFANQDYKHFE
                     AVEAYLDARRLRDIGELWAGSPEEMRSPYVSPLYGDYHDLPKIVTFVGTKEIFYPDIM
                     TLHERLMEQGHLNQLVIAEQMIHAYAIFPIREARQARKQIAELILKKE"
     gene            30679..31938
                     /locus_tag="TV191_000322"
     CDS             30679..31938
                     /locus_tag="TV191_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL1506872.1"
                     /translation="MAWDWKKAGVVGVVSLASIMVLSACSGGHQKEAKQKDDNTIVVS
                     VDEGYADYIKEIKTAFEKDNKVKVKVKKEGMIDTLDKLSTDGPTGASPDVFLAPYDRV
                     GGLGSEGQIAEVSLGNADQFDDTVKKLVTINGKVYGAPDVIETLVMYYNKDLVSEAPK
                     TFTDIEELNKDPKFAFASEDGKSVGFLAKWTDFYYGYGLIAGYGAYVFGDKGTDPKDL
                     GIGNAGAIEGLDYAKKWYSVWPQGMQDTQKAGDFITEQFTSKKAGVIIDGPWAAASFK
                     EAGVNFGVAQIPSLPNGGSYQAFGGGKAWVISNYSKNKKLAQQFLDYVTNEKNQKAFY
                     DKTQEIPANLAARSYAAEQGNELTKAVIGQFSNAQPMPNIPEMAEVWGPGANMFFEVA
                     AGKKTPAKAAKEAAKTIQEAIAQKYTE"
     gene            32111..33811
                     /locus_tag="TV191_000323"
     CDS             32111..33811
                     /locus_tag="TV191_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEL1506873.1"
                     /translation="MNTAGILHIPDSRYCFALSTKELVIRLRVAKEDNDIAVTLVYGP
                     KYHYHEYQKELAMYAAYTDHTHTYYEITLSLDDVRLAYIFKLEQSGHTYYFSEDGLTT
                     SYDFSNGFYNFFQMPYINAVDVHQTVPWVHNAVFYQIFVDRFHRGDFEKDDSYINMAW
                     LDRPTPNSFAGGDLKGITDKLEYLEDLGINVIYLTPIFKSISNHKYDISDYYAIDPMF
                     GTSLDLQQLINEAHQRGIRIILDAVFNHASSDCEPFQDVLAHGSASSFFDWFMIQGDH
                     PSVELANYETFADCHYMPKWNTSHQAVQDYLIEIGLYWITEYHIDGWRLDVSDEVSHD
                     FWRRFRKAVKAVKSDAILIGENWHDAYPYLQGDQYDGIMNYAFTKACLDYFAFDAISS
                     QEMAERLSHILMRNTWQVNQMNLNLLDSHDTHRFLTQVNGSKDKLLAGLALLVTFMGI
                     PCIYYGTELAMEGGYDPDSRRSFNWDSSTWDMSFWNQVKDIISLRRHAVIQFGSISIT
                     SHDDCLCVKRELNGQSIRLLVNNGVKPYPIEKGGSVLVSNGVDKETFELLQNGFVVSY
                     "
     gene            33840..35972
                     /locus_tag="TV191_000324"
     CDS             33840..35972
                     /locus_tag="TV191_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IPT/TIG domain-containing protein"
                     /protein_id="HEL1506874.1"
                     /translation="MKRITLTCRKALTVAMAAVTLAMSTNSVFAIENTAVSNKADFST
                     DTIYQIVTDRFHDGNAANNGNTDVFDKNDPKKYHGGDWAGIIKKLEDGYLTNLGVSAI
                     WISSPVENIDTIDPSNGSAAYHGYWAKDFFKANSHFGTMEDFKKLIQVAHGKNIKVVI
                     DFAPNHTSIAEYNGLTFPEDGALYKDGQLVGKFSHDDQKIFNHESWTDFSTYENSIYH
                     SMYGLADLNNLNPTVDDYLKEAIDKWLEMGIDGIRVDAVKHMSQGWQKNWLSHIYEKH
                     NVFAFGEWFADGSFNDPLMTKFADTSGMSLLDFRFANSVRRLYSDLSAKMQDFYNMIV
                     ATEKEYKEVSDQVTFIDNHDMTRFATLVNHNQTAVNQAYALLLTSRGVPNLYYGSEQY
                     ATGANDPENRGDMPTFDKNSTAYQVISKLAPLRKKNQALAYGTTQQRWINDQVLAFER
                     KFGNDVALVAVNKDQTNGYTISGAKTALPAGKYADELGGLLGGKELTVSADGNVEAFE
                     LGAGQVAVWTFKGQHETPQIGDVDASFGVAGNTVSISGQGFGSAQGQLHFGDSKADIV
                     SWDDTLIQFKIPAVAAGNHDIKVTTSTGQSSSPYKAFEVLTDKQIPVRLVVNNFNTVL
                     GEQLYIVGDVVELGANDNHKALGPIFNATQSIAQYPNWFYDVNLPINKTINCHLVKKD
                     SSGKVLWTSPETYTIKTDSKAQTISLKK"
     gene            36048..37352
                     /locus_tag="TV191_000325"
     CDS             36048..37352
                     /locus_tag="TV191_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1506875.1"
                     /translation="MLKNEKMKNPQKAMWLSIIPGLGQLYNTQKVKGFILLLVFLGEL
                     LEAFFVGIPALAGLYSLGSVPMEDHSLFLLIKGAMQLILFALFLIFHLAAMRDARLVA
                     REINAGHSISLTLKEMVQSIYEKGFPYLLIIPAYLAMAFAIVFPVLVTLLIAFTNYDF
                     RHIPPYKLLDWVGIKNFKSILELSTFKSAFGSVLSWTLIWTLAATSLQIVIGIATAII
                     ANQSFVKCRRIFGVIFLLPWGVPAFISIMSFGNFFNDSIGAMNVQVLPFLEKFVPFAD
                     FGIIPWKTDPFWTKVAVIMVQGWLGFPYIYILVSGILQSIPADLYEAATVDGATALQK
                     FRQITLPMIFAVAAPTLISQYTFNFNNFSIIYLFNNGGPGTVGGGAGSTDILISWIYK
                     LTTQTSPQFSIASAVTLIISLIVISVSLITFKKFKAFDMEDR"
     gene            37353..38213
                     /locus_tag="TV191_000326"
     CDS             37353..38213
                     /locus_tag="TV191_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1506876.1"
                     /translation="MGRNYLPQSVKKKRLLAQLLTYSYLLILSIIILFPILVTVSSAF
                     RPGNTTAFSFHIDGPWTLSNFETLFQDTYYLRWYWNTLVVAFFTMLIQVTVITLTGYA
                     YSRYHFFGRQKSLVFFLVVQMVPTMAALTAYFVMAWLFNALNHYWFLILIYVGGGIPM
                     NAWLMKGYFDTVPYDLDESAKLDGSGHFRTFYQIVFPLVRPMVAVQALWAFMGPFGDF
                     MLAKFLLREQEHYTVAVGLQSFITNDARDPKVTLFAAGAILIAVPISVLFFFLQKHFV
                     SGLTNGGTKG"
     gene            38238..39068
                     /locus_tag="TV191_000327"
     CDS             38238..39068
                     /locus_tag="TV191_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein malA"
                     /protein_id="HEL1506877.1"
                     /translation="MTNDRFPISYTTIIFSPKMIFARCSAFLWWQNVILVIFLNALVL
                     MPITLHYASLKSYPLEHIVSNGLDSLTEKTYHALTQGTIWHDRYDGKTVLIEDTDAVV
                     AVLPTPEIVEELKKDQRSQLILTETSWILSFPDGQRLTAKVKGNKERLTRLTSLEAVK
                     AFVNQQWYNSNRAAVLAFLLLVASSVVYLGAGLVIGIGSLSLLLTRSARLFSLKSYSE
                     CLGLLVNCFGLPTLLAVLISFWVHNPIVIMNSQVFGTLLMLVLVFYKTQFRDEEQALA
                     "
BASE COUNT        10877 a         7381 c         9049 g        11789 t
ORIGIN      
        1 tgatagtgga aattatcact caagaagtac ggggtatcag agcaagactt attttaatct
       61 gagtaagctt cttgtcctta ggctcaagct gatcaggact gagtgaccac ccatttaaac
      121 cggggaacaa ggtagctaac gataatgctg ctaagtccaa taatggttag ccaataaagc
      181 cagctggaat caaagctaag cacgagatga cttccaagga caagcacaac accagaccaa
      241 aacaagatta gattaatcgg gttatcagtg atagtgacct gatcttgatt ggtcacgatt
      301 ttcttggcct gcctgctatg cttgatggtc aaataatcct cagcatcggg gagatcaata
      361 tcgatactct cacccggata aagcttaacc ttgtgggatt tcccgatatt aactgtcata
      421 ggtgctccta tctttgtcaa acgtgtcttg cgccttagct tcattcctaa aatcctctct
      481 aaaataaaag tcaagcataa tcatgccaat tccagccttc aaatgctaca aaagaccagt
      541 gtaccatagc ctatgatacc aaaaagcaga aagaatagcg actgtaaaaa atctgaaaat
      601 aagctttctt acatctattc cctgctttga aagcagactt ttgcaggatc tatgctagaa
      661 tagaaggaaa aggagggcac taatggttaa gggaataata tttgacatgg acggcgtttt
      721 atttgatacg gagccttttt atctcaaacg tcgtgaagcc tttttgacga gtaagggcat
      781 taggattgac cacctcagcc ccgaggattt tattggtggt aatcttcagc agatttggga
      841 caaggtctta gcagggcagg ctaatgctga tgaggcaaga gatattgctg tggcttatga
      901 ggcctataag ctgtgccata agcctcctta ccaagagctg atgtttaaag gggtcaagtc
      961 ctgcctcaaa gctcttaaag ggcagggact taagcttgct ttagcctcaa actctagtcg
     1021 ttgtgatatt ttgttagctt tagagagcag tcatatcaag gcttattttg accttacact
     1081 ggcgcgtgag gacgtcacag ctggtaagcc taatcctgag atttataaca aggttgcgca
     1141 ggctctggga ctggctaaag cagagtttgt cgttgtcgaa gatagtcaaa aagggattgc
     1201 cgcagctaag gctgctggct tgaaggttct agcaatcaaa gacaagcgtt acggcattga
     1261 tcaaggtcag gcagacaagc gcattgatag cctcaggcag ctatgtgagc tgcttaggta
     1321 aggcttctga tagagcagat gtttgttaac tgaaagatag caggctttat agtggcttat
     1381 catcactaca atagaatgat ttgtcttaga atgacagaac ctaaataggt gtttttctcg
     1441 tttttgtagc aggatagctg aagcttttga tctgctttat gtttggtgtt gttattaaga
     1501 gatgaaattg tcagtaatgt tgagcttact gataggaggg ctaatggcag ttaaattatt
     1561 aacagaaaga ttgatcatac aggagttgaa tgagacctat tttgagcctt atcacaaggc
     1621 atttaccgaa gaaatcacag catttcaatg gcctgatccc tttaaggaca tcgctgctgc
     1681 taaggagaca ctagctagct ttatcgcaga aatgaaaaaa ggaaacatgc tagagctagt
     1741 cattttgaat aaagcaaatg acttcgttgg aagcttggaa gtctttagcc ttgatagtga
     1801 gacaccggaa ttgggcatat ggttgaaaaa atcaagtcaa ggactaggct atggctatga
     1861 ggccttgaga gctattgtgg attatttaaa aggcaaaaac aaataccgtt atttcaatta
     1921 tgaggtagat gttagaaata ctggtaatat taagctggta gagaaattca atgtggtgac
     1981 atcgacctat caggaatgtg agacggcttc aaagaaaagg ctttgtttac aggtttatca
     2041 cattcttaat taatcgttgg tatgacatag gtgatagtca tggttttgct ttaagtcctg
     2101 tgtgagttga gagcagcttt cagctctagt atttgcttct ggtgtggtct tttagtccac
     2161 agtctaggta ttataaagaa gagatctggc tttgtttaaa aaacagcttc tctgtctgag
     2221 cttgtaccct caagatatca ttgaagagat agcaggacag ctgttgaaaa tgagggaagt
     2281 aagagggatc tgtgtgccaa gatcaaaagc ataaaaagcc tctagcttac ttcttgtggt
     2341 tagcattttt ttgaaagcat gctaatttgc ctttagtgtg ctttttgttt gctcaagatc
     2401 agctagtcaa tgaggccata gagtaagcct taacaaatgg tgagatgtag ctacagccgg
     2461 ttgtgcagat ggggttagaa taattggatc tactcacagc ctcttgtaat catttcctta
     2521 caaaaatcac actagtaaag acctctaatg gcgaaggagc tcctgacacc aagctctgaa
     2581 gaagctggct atttgtcctt gatcaaaaag ggttaagact gtcagttcaa ctaggtgcaa
     2641 acgactcata aggcaggtct ttagcagggg tgatgtcaaa aaattgacat cagctgtaac
     2701 cttttagcaa aattgtagtc caacaaaagt gagcagacat tttggaaggg ggacctgtta
     2761 ttggaatttg aagacatcta cttgatgtat aaagacgatg tttatccttt tcttcatgcc
     2821 tatgcgtgag acaacttatg acgaggttga accaagggct ttctttatag tataatggtc
     2881 gttaaagtga tattaataag aaagtgatga ctataatgac agaaatacca aaggatttaa
     2941 agctaaatac gattagtgtc tttgagcatt atcatattga tgtgtttgag gctggtcatg
     3001 tgctgttatc aacagagatc catgcgtcag ccttgaacta ttatggaaat gcacatgggg
     3061 gctttttgtt taccctttgt gatcaggttg gtggcttggt ggccaaatca ataggtcttg
     3121 aggctgttac tctgcaagct aatgtgaatt atcttaagcc tggtcatcta ggagaccgtt
     3181 tagtcgtaga aggtagtctg gtgcatagag gtcggaccac acagctgatt gaggtcacca
     3241 tcaaaaatca agatgataga ctattaacca gggttagcct gaccatgttt gtgacaagta
     3301 aaaaacgatc ctctgactag ctgatacaag tcatatcaaa aaacgtccag cttgatttta
     3361 gctggacgtt tggctttagc tgcgatagag cttatggtgc tgataaacag ggtcaaaggt
     3421 cacattgata ccgagctgtc tgagaacatg cttgtcctcg ttggtcagga taacggttga
     3481 atgcgcttcg ctgcccttga gatttcctaa ttctttcatg gctagatcgg cttggttgtt
     3541 gttcattgct gtgatagcca gcgccattag gatttcatta gcgtgtagcc tagggttgtg
     3601 actgcctagg tgattaatct tgagcccttg aatgggcttg acatattctg gctcaatgag
     3661 atgcgtttcc ttactaatgt gggccagtgt tttgatagca ttgatgataa cagcagcggt
     3721 cggaccaaac aaatcagatg ttttaccggt gactacctga ccatttggaa gctgaagggc
     3781 tagggcaggc tgaccagtta tctctgcttt ttgcctagca atgagagtaa cctgtcgatc
     3841 tttgggagtg acaccgatgt cattcatcaa gagctcaagc tttttaactg cagcctcggt
     3901 cacgcgctcc gctttgaagt ctaccaaggt ttgatagtag cggcgaatga tttcttgcct
     3961 tgaggcttcg atagcagcct cctcattaac aatggaaaag ccgaccatat taacacccat
     4021 atctgttgga gatgcatatg gggactggct taaaatacgc tcaaaggttc tgtttagtac
     4081 tggaaagacc tcaatatcac gattgtaatt gactgctgtt ttcccgtaag cctctaaatg
     4141 aaagggatca atcatgttca catcatctaa atcagcagtg gcagcctcat aggctaggtt
     4201 tacagggtgg tggagtggaa gattccaaac agggaaggtt tcaaactttg catagcctga
     4261 tgtgacaccc tttagttggt catgatagag ctgtgagatg caggtcgcta attttccaga
     4321 gccaggacca ggagctgtga cgacaatcag gttacgactg gtcttgatgt agtcatttct
     4381 ccccatacca tcaggagaaa tgatgtggtt aatatctgtt ggatagcctt tgattgggta
     4441 gtggcgataa gacgtaatgc catttttggc taattgcttt tgaaaatgat ccgcagctgc
     4501 ctgatggttg tactgcgtaa ttacaactga gccaacatag atatctaagg cgttaaaggt
     4561 atcaattaaa cggagcactt cctgatcgta ggagattcct aagtcaccac gcgttttaga
     4621 atgttcgata ttattggcat tgatggtgat gacaatctca acctgatcct tgagctcctt
     4681 tagcagcttg attttgttgt caggctcata gccaggcaag acacgcgccg catgaaaatc
     4741 ctcaagtatt tttccgccaa attccatgta gagcttgccg tcaaattgct tgatacgttc
     4801 tagaatatga ttcctttgta agcttaggta tttgttggaa tcaaaagcaa tgtttttcat
     4861 ttatttttca cctctgctaa gcattatagc aaagaaatag tgagaagtga atgatttgtc
     4921 taaaaattag tctcttcctc taagtagcta gggtggcaaa aagcagcgct atttaaatac
     4981 cgataaaaaa tgacttgaca aaggtgactg acttgcttat actaggaaca attaaatacc
     5041 actttaatga tgttctgtga ggcatgaaag tgacaagaca aagaggagtg agcctgctct
     5101 tattttgctg tagactgaat gcgactgatg gactggtgcc taggtctttt ttaatgggct
     5161 taaagggtat tcaattaatt aaggtagtca gtgagctact attaaaagga gaataatcat
     5221 gtcagcattg tctttagaca agaacaacaa gcgtgcgctt tgggctgcta ttgccgcttc
     5281 aggaacagat gatcttaacg ttatgtttct agccttttcg atgtcctcta ttatctctga
     5341 tctaggagtg agtagtactc aaggaggctg gatagctact atcactaatc taggaatgct
     5401 ctttgggggc ctgctctttg gtctgcttgc tgatagacat cataaattta aggtattcaa
     5461 atggacgatc cttatttttt cagtggcaac aggcttgatt tattttacca agacgattga
     5521 atttttatac ctcatgcgct ttattgctgg tattggggtt ggtggtgaat atggtgttgc
     5581 tattgcgatt atggcaggac ttgtccctgc tgaaaaaatg gggcgcgtct catcgctaaa
     5641 tgggattgca ggtcaggttg gatcaattgt ttctgcttta ttagcaggct ggctagcacc
     5701 tgctcttggc tggcgcggcc tctttctctt tggtctggct ccgattttac tagtcatttg
     5761 gatgatggtt gctattgatg atgataagat tattgataac catgtcaatg tttcagagga
     5821 agctagtcag ccggtaaaga ttagtgagtt atttaagaca ccagccttga caggacaaac
     5881 tctcgctttg atggtgatga cgacagttca gattgctggt tattttggta tgatgaactg
     5941 gctgccaact attatccaag ctagtctaca tatttctgtc aaggattcgt ctctgtggat
     6001 ggtatcaacc attgtgggca tgtgccttgg aatgctgacc tttggccatc tgctagatac
     6061 ctttgggcca agattggttt attctatctt tttgcttttg tcctctgttt gtgtctatct
     6121 ttttcagttt gccaattcga tgtcaaccat gcttattgga ggagctattg ttggattttt
     6181 cgttaatggc atgtttgcgg gctatggtgc gatgatcaca cgactctatc ctcatcacat
     6241 tcgatcaaca gctaataacc ttatcctcaa tgttggacga gctgttggag gcttttcatc
     6301 ggttatcatc ggtaaaattc ttgatgtttc aagtgtctct atggtcatgc tctttttagc
     6361 cctgctgtac cttgttagct ttgtggcttt gtggacaatc aaaaatctaa aggcagagcg
     6421 atatcaagcg ctgacaaaat agatctggta agtgtagtag gattagtagc aaaggttttg
     6481 ttaaagctct caaaaagcgc ttaggcattt agactaagcg ctttttgacc tttaaagctt
     6541 ttccaaaaag gcgtcttggt caaccctgac acgtgtgtgg caggctctgc caatgagctt
     6601 atggttggca aaggcttcga tacgaaagtc gtattttctg ccctcttcct tgagtgcagt
     6661 gataacaatg gttactgcct gaccgatttt agaggcagct aggtgctgga tagcgatttc
     6721 acttccaacg gttgtttgct tgtcctttag ctgactttgc agaaacgtga aggcagcatg
     6781 ctccataaag gcgacaagag caggtgttgc taggacctct aagccaccag agcccattgc
     6841 ttgagcagaa tgcttgcttt ttgtttcgta tagctgtgaa taaatagaca tgataccctc
     6901 cttttttatt attataatat attaagggct tacagtctta aatgagctgc cttttgtgct
     6961 atactaagaa ttagcttgaa agagctgttg ctgaattaat gtgtctcgca tgggccagac
     7021 taagcatcag ctaacagtaa gaagaagggg aatacatgcg cttagataag tttttagttg
     7081 atgctggctt aggcagtcgc agtcaagtga agctgctatt aaagaaaaag caagtcagtg
     7141 tgaatggggt tagccaaacg tctccaaaat atcaagtcaa tgaaatgacc gatgaggtta
     7201 gctatcaggg acaaaggctc aattatgagg cctttgtgta ttatatgctt aataagccta
     7261 aaggagtgat ttctgcgact gaggattcta gccataagac agtgctggat ttgttagatg
     7321 atactgcacg tcaaaaggct gtctttcctg ttgggcggct tgataaggat acgcatggct
     7381 tgctcttagt gaccaatgat ggaaagctag cacatgctct tttgtctcct aaaaagcatg
     7441 ttgccaagca ataccttgct gtggtagacg gtatgatgac tcaagaggac gtcaagcatt
     7501 tcgcacaggg aatcacttta aaggatcacc aatgcatgcc agcacatttg gacattcttg
     7561 agattaacga atcgctaaaa accagccttg tcaaaatcac catcgaggaa ggaaaatttc
     7621 atcaggttaa gcgaatggta gcagcctgtg gtaaaacagt cagcgattta cagcgcatta
     7681 gtatggggcc cttacagctt gatagtgctt tggcgcctgg agcctatcgt aggttaacag
     7741 cagcagagct agaggcctta aaagcctaag gctagactag tcactggctg ggttagctgc
     7801 tgaattgata gtaaaaaaga ccagtcttag actgatctgt agggtgatta gatcgcccat
     7861 tctcctcctc ggaagattgg aatgacttct ccgtctttgg taatgccatc gatatccatt
     7921 tgttcagaac caatcataaa gtccgcgtgg gctgttgagc gatttaggcc agccgcttcc
     7981 caaatgtgct gctcaggcat tccaagtctt aggtcagttc ctggtgccct gtagtgaagg
     8041 ctgtcaaact gataatcatt gaggagcctt gccttttttt ctaaacgttc ctgatgttgg
     8101 tcccaggcct tgacaggatc tgtctcgtaa atgcgattca ttttgaaaat ggcatcccac
     8161 aaagcgtcca cctgctcttc ttcgcttgtc aggtttggaa aaaccatagc agcccattcg
     8221 ggaccggctg cagctgctag attccagctg actttgttgg cctgagtggc agcccgctgt
     8281 ttttcaagag caatagctgt tgcgcgtgtt gctccagcta gcctatcaga atcaatatca
     8341 gcaaagacgt ttggattggc agagcgaatg actaagcggc ttgctttttg atcaaggaga
     8401 taatgtgact gttcaacgac ataatctggt acctgcaaga gacggtcttc atcagcctta
     8461 agaagcttct cgcgtgtgat ctgatcgtca ttatagtcaa caagaacctc agctgcacca
     8521 gcctcatagg cttttttggt taatagccgc gcaagcttgt gttgctctac tgcaatagaa
     8581 atgagtagtg tgtgaccttt ttgaatgttg actccttttt tgataagaag gttagcgtat
     8641 ttttcaagat aatcgtcaaa atgtggcaaa accatagcag tctcctaata tgttaatgtt
     8701 gcaaaattta atgtatcata tttgcgacta tttcacaagg agctagcctg tttcataggc
     8761 taaatgtctc ctagaatgcc tatcgtaaaa ggctcagtgt tggttttctc tgatgagtta
     8821 aaaaacgatc ccttttttga tcagtttgcg ctgcccttgc taatagatat ttgcttaata
     8881 gcgacattcg tgttaagata taagaggaaa aaatcaatag atgaggtatt taacagtggc
     8941 atttggagaa aatggacctc gcaaaaaaac tgcctttgaa aagttgacaa cagttgttgt
     9001 gatcgtgatg gttcttgtga ctgtcggtgg acttattgcg ggtgccctgt cagtattgat
     9061 gtaagaaaac gctgaaaggc gtttttttag gataagagaa ggtttgagaa gaaaagtatg
     9121 agtatgtttt tagatactgc taaggtcagt gttcaggctg gtcgtggcgg tgatggtatg
     9181 gtggcctttc gtcgtgaaaa atatgtgcct aatggcggcc cttggggcgg tgatggtggc
     9241 aagggtggct ctgtcatttt caaggttgat gaaggtttgc gtaccctaat agactttcgc
     9301 tacaatcgta agttcaaggc caaatccggt gaaaaaggca tgactaaggg catgcatggt
     9361 cgtggctcag aggatttgat tatctcagtg ccacagggaa cgactgtgcg tgatgctgaa
     9421 accggtaagg ttctgacgga tctggttgag catggtcaag aatttgtcgt ggctaagggt
     9481 ggtcgtggcg gtcgtgggaa cattcgtttt gcaacgccgc gcaatccagc acctgagatt
     9541 gctgaaaatg gtgaaccagg agaggagcgc caattagagc tagagcttaa gattttggca
     9601 gatgtgggac tggttggttt tccgtcagtt ggtaaatcaa cgctactaag cgtggtctca
     9661 tcagccaagc ccaagattgg tgcttatcac tttaccacta ttgtgcctaa tctaggtatg
     9721 gttcgaacca aatctggtga gagctttgct atggcagatc ttccaggctt aatcaaggga
     9781 gctagccagg gtgtggggct tggcactcag tttttgcgcc atattgagcg tacacgtgtg
     9841 attctacatg ttattgatat gtcagcagct gaaggacgag acccttatga ggactatgtg
     9901 gcgattaata aggagttaga agcatataat cttcgtctta tggagcgtcc gcaaattatc
     9961 gtcgccaata aaatggatat gccagaggca aaggagcagt tgcagcgctt caaggaacag
    10021 ttagctgctc agtatgatga ctttgaagaa ctgccaataa ttttcccgat ttctagcttg
    10081 gcacatcaag gcttggatag cctattagaa gcaacagcag agctattagc aaaaactgat
    10141 gatttcttgt tgtatgatga ggctgatttg gctgaggacg aggcttatta tggctttgcg
    10201 gctgaggaaa aggcctttga gattagtcgt gctgatgatg cagcttgggt attgtctggt
    10261 gagaaattag agcgtctctt tgtgatgacc aatctggagc gcgacgaatc tatcatgaaa
    10321 tttgctcgtc agctacgtgg catgggtgtt gatgaagcgc ttcgtgagcg tggtgctaag
    10381 gacggcgaca ttgttcgcat tggcaagttt gagtttgaat ttgtagacta atgacaaata
    10441 ccaagcttag ctgttttttg tagcaagtga tgctgagtca tatctgaagt aggctgtttg
    10501 ctcaattcac agcaatgagg tcttggttga tgtgagctag ggaggttttt tatgggagat
    10561 aaaccaatat ccttcaagga taaggacggt aactttgttt cggcagcaga tgtctggaat
    10621 gctgaaaaat tagaagaatt atttaatctc ttaaatccca ataggcgttt gcgtttggaa
    10681 cgtgacaaat taaaaaagga tgaagcttaa gtgcacttcc tctcaatcgt tagatttagt
    10741 gtctaacttt tgagggtgca cttcaaggct tcgtcctttt ttgatgcttt ttttcttggt
    10801 gatgctgcaa atgtagccaa ttaaaaaagg tgtaaatgtc attaacaaga aaggctgcaa
    10861 aacaaatgac cactgcgtat tggctggtat ttgcttgagc agcatagagc cacaggagaa
    10921 ttaagaccaa atcattaaga gcataggcca aggcaaaata agggctacgt ttgtagctta
    10981 agtaggctgc tgaaaaagag gtggcaatag ataaggtaga aacaggcaga taggctgtct
    11041 taagataggc taagatagca tagaacaagc tggtaactag tatggtaaga accactaagc
    11101 gcagccggtc tgctgttgtc aagcgtgaga tggttacctg agatgtctgg tcttcaaatg
    11161 ggtggcttag ccaggtaaac agtgacaaaa tagccatcgg cagggtcatg aagagatagg
    11221 ttatcagctc cccgtaataa ctgtttaata gtgacagata ggcataaata agggagaaaa
    11281 taatggccaa gctctgtcca atcggatttg ccttggcact aaagattaaa gctgtcacac
    11341 cgattaagga agctatcagt gctaagggag cttgttctcc aaagaaaaag gcactgagga
    11401 gaatagccga aatggaggtt aaccaaagcg tccactcggt ttttgtaaaa tagtttaaat
    11461 aagccatatc cttattcaag cataggcctt tttatctgtc aatagggtgt cgaccttagg
    11521 gaaaaataag ctaatacctg ccatagtgca attggttgtg aggcactaat actagcagat
    11581 aatggtgtta actagaggca aatgagctaa gagtttcctt attggctgct gctaatactc
    11641 cttgttgact ggtttagaag aaaaggacta agagccttag cttggctttg tcagttagtt
    11701 tccttgatga taaggaaaaa ctagattttt taaagcgttt acagtgtcct tttttcttcc
    11761 tataataggg gtataagtga caaaaagaaa ggaaaaagca tatgaagcaa tcaaaacgcc
    11821 gttaccaatt tccagaaggt tttttgtggg gaagctcaac atctggccct caaagtgagg
    11881 ggactgtttc tggagatggg aagggaccta gcaattggga ctactggttt agtctggagc
    11941 cagataagtt tcatcatcag attggtccag aggtaacctc aaccttttac accaactaca
    12001 aaagcgatat tgctctttta aaagagaccg gtcacacagc ttttcggacc tctattcaat
    12061 ggtctcgact gattccagaa ggggttggtc aggttaatcc aaaagctgta gccttttacc
    12121 gagaggtatt tcaggaaatc atggctcagg acattaagct gattgttaac ctctatcatt
    12181 ttgatctgcc ttatgccttg caaggaaaga gaggctggga ggctaaggag acggtctggg
    12241 cttatgagac ctatgctaag acctgttttg agctttttgg tgatttggtg gatacatgga
    12301 ttacctttaa cgaacctatt gttccagtcg aatgcggtta tttggggcat taccactatc
    12361 cttgcaaggt agatgccaag gcagctgttc aagtggctta ccatacccag ttggctagct
    12421 cacttgctat caaggcctgc cacgagttgt atcctaagca taggattagt attgtgctta
    12481 atgtgactcc tgcctatcct agaagtgatc agccagaaga tgtcaaggca gcgagaatcg
    12541 cagagctttt ccagactaaa tccttcctag atccgtctgt cttaggagtg tacccagaag
    12601 agttagtagt tcttttagag gcagctgatt tattgcccca gtatagtgct gatgaattgg
    12661 ctattatcaa aaacaatcct gttgatttct tgggagttaa ttactatcaa cctttgcgtg
    12721 tgcaagcgcc tagcaaaaca agacaagatg gtgaaccaat cacgctagcc tcttattttg
    12781 aaccttatga tatgccaggc aaaaaggtta accctcatcg cggttgggaa atctatgagc
    12841 agggccttta cgacattgct cttaatttaa aagagcatta tggcaatatt gactggttag
    12901 taactgaaaa tggtatggga gtagaaggtg aagaagcctt tttagttgat ggtcagatcc
    12961 aagacgatta ccggattgcc tttatcgaag accatttgat tcaattgcac agggctttag
    13021 aagaaggcgc gaactgtaaa ggctacctcc tgtggacctt tattgattgc tggtcttggt
    13081 taaatgccta taaaaatcgt tatggcttgg tagccttgga tttagagact caaaaacgaa
    13141 cccttaaaaa atctggccac tggtttaaga ccctgagtca gacaaatggt tttgataaat
    13201 aggagcgtat gatggtcacc ttaggatttt ccctttaccc tgagcggcat ggttttgcta
    13261 agagtaaggc ttatattgat ttactgcact gctatggagc caagcgcttg tttatgagcc
    13321 tcttacagtt ggcgccaaat gatcccaaga cctttaagtt ttatgcggat ctgattgctt
    13381 atgccaattg cttgggcatt cgggtcattg cagacgttag ccctgctttt atcaagcagg
    13441 ctggttggtc agatcaggtt attgaagagg ctcatgcttt tggcttagca ggcttgcgtt
    13501 tagatgaggc cttgccttta gaggatattg ttaggctaac gaaaaactct tttgggctta
    13561 agattgaact caatatgagt actgacaaga gtttattgac agccttgcta aaggcagctc
    13621 ctgatcggag taacctcatt ggttgtcata atttttaccc gcacgccttt accggcctgt
    13681 cactggagca ttttaaggaa atgtcccatt tttaccacga gcatgggatt gcaacggctg
    13741 cttttatcac agcccaatca gcaaaggaag gcccttggcc gctgtcagag ggcttaccga
    13801 ctgttgaggc tcatcggcaa ttgccaattg acgtgcaggt ggaactgatg aaggcgacag
    13861 gaactattga tactgtcatt ttgtccaatc aattcatcac tgaagatgaa ctcgttcagt
    13921 gccgtcaagc cttggataga tcagtcatgt ctattaaggt caagcctctg gttgatttga
    13981 cggacataga ggagaagatt atctgttacc cacattgtta tcggggagat gtatcagatt
    14041 atgtgattcg ctcaaccatg ccgcgtgagg tatatgctca agaagcaatt gctccaagag
    14101 agcagcccaa gcaggttaag cgaggcagta ttatcattga taatgaccgt tacaacaggt
    14161 acaagggaga attgcaaatt gcactcaaag cctttaccct tagctcaaag gccaatgtgg
    14221 tcgccaacat taaagaggat tacctaagcc tattagacga gttgaagccc tggcaggagt
    14281 tttcattggt gattgagact gactagtctg gcttcacaat cgatacggaa aatgatggtc
    14341 acttttttca ggaaacattt gctaaactaa gagagtaaag aaagcgtttt ctaaaagacg
    14401 aaggaggaat gatgctatca aaaaaagaaa tggctatagt agcatttcta atcagccaaa
    14461 aagggcagtt tgtctctagt gctaccttgg ctaaggctat tggcatgagt gatcgcacag
    14521 tcagaaaata cctaaaggag ctgattagca gccttcctag taagggagcg cacatcattt
    14581 ccaagcaagg tcagggctac tgtttagaga ttgatcattc tatggcgttt gagatctttt
    14641 ggcaggaaag cttggcctct aaaaagcgct tggctgatgt gactcaggtg gaagaaacag
    14701 ttgatcggga gcattatttg ctaaataaat tcttctttga agagcccgtt tgggattttg
    14761 aagagctctg ccaagaattg tatattagtc ggacgaccct aaaccatgtt ttagcggtta
    14821 ttagagaccg tattaggcct tatcagctac agcttgatgt gagtcatcag cgcgttcagg
    14881 tgacaggtaa ggaagaggct attaggcatt ttatcatgga ttattttttt gctaccagct
    14941 ttgatgactc catgtacgcc atagtagaca atacctttct tgatcatatc aagtttgctg
    15001 atatcacaat aattgtttta gatgaatgtc gagatgccaa actaaagctt tctgattttg
    15061 tcatgcacaa tttggttttg cacattgccc taatggttca gcgtattcgg tctggctatc
    15121 cgttagcatt tttttccatt ccagcagcta ttcgccaatc agacgagtat caagtggctc
    15181 tacgtatttt atatcgagta gaagaagtga tgggcattcg ttttcctaaa gaagaagcta
    15241 actatattgc tttacacctc aaggttaagc attccgttga tggcagccca caggacaata
    15301 aggccgatga cttgctgaga agtcatttaa aagcaggtat tgtcaaggct agtcagctga
    15361 caggtatgtc tttggaggct gatagcagct tgcttcaagg cctattggcc catatgaagc
    15421 ctttagccac aaggcttgaa aatcatattc agctgaccaa tcccttaact gaggagatta
    15481 aaagcaaata cccagaggct tttgccctga ctaagcaagc ttttgagaat attcctgagc
    15541 ttcaggctta tgacctgtct gatgacgaat gggcttacat tagcttgcat atcatggcag
    15601 ctattgagcg ctattccaat cgtcacaaac tgagggtgct tgtggtttgt gccacaggct
    15661 atggcagtgc catgatgctg aaaaatcgct tggaaaagga atttgaaggt cgctttcaga
    15721 ttgtagatgt tatcagctac tatgaaataa cacaggaacg actgcaaacg gttgatgtga
    15781 ttatttcttc tatcagcctt gctaatgtca tgtttttaac gccagtcatt actgtcagtg
    15841 tctttttatc tgatcaagac atcaaagcca ttcgccaatt tatcggggag caggagggaa
    15901 taagaagaga agctgcgtcg tcatcgcaga tgagcttgga aaaagcagag cagattctaa
    15961 aaggtgtctt tagtcctaag cgttttcttt atgtgaaaga aaaactatca aagaaggcct
    16021 tgctgttaaa gatgattgct tgtcttgacg aagcaatgga tgaagccttt gttgaggcct
    16081 tttatcacca aatcgtgttg agggaaaatt atagctcaat tgtttttggt gaggtgcttg
    16141 cctttccaca cccggctaat cccatgacct attctgaaca ggtggtggtg gctgtctgtc
    16201 aagagcctat tgactgggac gagagtcatc gggctgttca ctttatcttt ttgttgtcac
    16261 cgtccaaggg acgtaacagc tatttaaaat atatctcacc gagcttggtg tcttttgtca
    16321 atcaagcaga gcttcagcag gctttattag aagaaccaag ctatgcacaa ttcatcacat
    16381 tatttacccc actcatcact gaataaaagg agaagtatta tgaaaaccat tatgttagtt
    16441 tgtaatgccg gcatgtcaac cagtatgctg gtgactaaaa tgcaaaaagc cgctcaagcg
    16501 cgtggcatcg aggttgagat ttgggcagtt cctgtgagcg aagctgacaa tgaggttgct
    16561 gctaaaacca ttgatgtcct catgttaggg ccgcaggtca aattcttact aaaggacttt
    16621 aagaccaaat ttgaaccggc aattaaggta gatgtcatta acatggctga ctatggcctc
    16681 atgaatggtg acaaggtgct tgaaacagcc ctaacaatga tggaggaaga ggtatgacac
    16741 aatcatcaaa cctagaggcc attatgggat taatcatgta tggcggtgag gccaagggca
    16801 aggctgtaga agctattcat gcagctagag atggtcaatt tgaaaaggct cagcacttgc
    16861 ttcaagaggc tacacattct ttaaatgttg cccatagatc acaaaccaat ttgctatctc
    16921 aggaagcagc tggagatcag gttgatttgt ctttattgct ggtgcatggt caggatcata
    16981 tgatgacagc cttagccttt attgatttgg ccaaggaatt ggtcgctgtt tatgacaaaa
    17041 tatcaagaat ccaaagaggt gagctatgat gatgattaca gcagaaggag atgtctctgt
    17101 cactcaatgc ttcaaggcta tactaagctc tctccaagag gattatcatg aaaacaccct
    17161 gagacggctg ccaccagctg aattaaaagc agggctaagc tacataaagc attatggcaa
    17221 aagcaaggag cataacgtta gagtgctgat cacagcctta gaagctccgc acttatatgc
    17281 tgcttgcttt agctctaatc atgggctaaa aacattaagc taccgcttag aagctctggg
    17341 agagaagcgt accaaaataa cctattgcta cgactatcag ccacttgatg tctttcaaaa
    17401 agccaatcag ctgatcattg ggaagctttt taagaagagc ttcaaacggc aatcacaagc
    17461 ccaattggca gcccttatcc aatatgctaa gcagctaagc taggggaaga tttgagtaca
    17521 gattatctgg ctgattatag ggcttatcat actaaaaaat agaaacagga gaaaattatg
    17581 tcacattttt cggataagtt tatggagatt tcaggaaaga tgggatccca gcggcatttg
    17641 gttgccattc gtgattcctt tatttcgcta atgcccatca cgatggcggg ctctgttgcc
    17701 gtcttgctga atgttttctt gcgtgatatt ccaaacaata tgggctggac tggttttgca
    17761 gcagccatgc agcccattat tgacatcaat ggttatgtgt attttgggac aattggtatc
    17821 atggcactct tttttgcctt tgcttttggg tatcatttag ctcttatgca caaggtgaat
    17881 cctttggctg gaggtttaat ctcctttgct tcctttgtcg ccacccttcc tcaaagctta
    17941 accatttcca caccacttga aggggcgtca gcaagtttat tagcaggctt aaaggatatg
    18001 ggactatcag tggtcactgc aaatggagcc cgagttttag aaacaagcca gtggggagca
    18061 attgccctca aatatgctgg agcaacaggt ctttttacag cattgatcat tggcttttta
    18121 tctagctttg tttatgcgac tttgaccaaa cgtaacctga ccatcaaatt gccagataat
    18181 gtgccacctg cggttaataa ggcttttgcg gctattattc cagggacagt cgcgatttat
    18241 gtgtcagcga tcgtagctta ccttattttt gccctcacag gctcgtctct aagtgatatg
    18301 atttcgacct atatccaatt gcctttgttg gggctgtctc aagggcttgg ctctgttatc
    18361 ctgttaacct tcttggttca attgctctgg ttctttggtt tgcatggtca caatgtctta
    18421 gcacccgtgc ttgatggtgt gtacttagtg gctctaacag aaaatacagc tgcctataat
    18481 accagtcaga gcgttgctaa tctgccttat ctctggacga gaggctcctt tgatgcctat
    18541 gcacaaatgg gtggttcagg tgttactctg gctctgatta ttgctatctt tattttctca
    18601 aaacgtgagg agcacaagac cattgccaaa ttatcagcac cgatgggcgt gtttaacatc
    18661 aatgagccaa ttacctttgg tatgcctatt gtcttgaacc caacctttgc tatcccatgg
    18721 ctaatcgtac caccaatttg tgctagcatt gcttatgctg ccacagcaat aggcttgatc
    18781 cctcccgttt tcttgccagt tccttggatt acgccagttg gactttacgc ttacttggct
    18841 actggaggta gtgttatggc aggtctggtt tccttgttta acctctttgt tgcctttctt
    18901 atctgggcac catttgtcat gtcagctaat aaagaaaaag cgagtgacct ttcatgacag
    18961 caaaaaacgg agcaagcttt ttaatggcta taggattttt ccttattgcc attagtccaa
    19021 tggttggcaa caaataccta catatcgtga caggactagc ttttgttggc ttagggtatt
    19081 atctcactaa gcgcaagcgt ccttagtcaa tgcgagcagc tagcccctat gaaaagacaa
    19141 acctaagggc tagccttgat tttctatctt ggttatcgca tttaaaagca agcaaaaaag
    19201 caagggtaga tgcttacctt tgcttttttt attttttgac ctttaataga atatcttgct
    19261 acttaaacat ttaagacctt atctaaaaat tcaattaagc gtgggtgctt agggtgatca
    19321 aagatttcct ctggagtacc gtcctctagg aattggccgc cgtctgtaaa gatcacacga
    19381 ttagccactt gacgagcaaa gcccatttca tgtgtcacaa tcagcatggt catgccctgc
    19441 tctgctaggt ctttcataac gtttaagacg tctccaacca tctcagggtc aagagcagag
    19501 gtaggctcat caaagagcat gatatcaggg ttcatggcaa gacttcttgc aattgcaaca
    19561 cgctgctttt gaccacctga tagacttcct gggaaagcgt cagccttatc agctagaccg
    19621 accttctcta gaagagcaag tcccttttcc ttagccgcct cctttgagac ctttccaagc
    19681 tcaactggtg caaaggtaat gttatcaagg actgtcatat gtggaaagag attgaagtgc
    19741 tgaaacacca tgccgatatt ttcacgagcc ttatcaatat tggtattagg atctgaaagt
    19801 tcaaagccat caaccacaac cttaccacta gtaatggatt caaggagatt gagggtgcgc
    19861 aggaaggttg attttccaga gccagatggc ccgataatac aaacgacatc accctcgtaa
    19921 aatttagcat taatgccttt taagacctca ttttgcccat aggatttgtg taaatcttga
    19981 acatcaattt ttaattctgc cattagttaa gcctcttttc taaacgtttt gcaagccttg
    20041 ttaagagtgt aatcataatc aagtagataa ctgctaggat agcatacatg cggaaggatt
    20101 gatagtttct agcgataatg attttccctg tttggaagag ctccactaaa ccgatcgctg
    20161 agactatggt cgtatccttc aaggaaatga caaactgatt gatgaagttt ggcagcatta
    20221 gcttaatggc ctgaggaagg ataatccttc gcattgttgt gtgatatgac aagcccaagc
    20281 tgcgactagc ctccatttga cctgccggca cagcctcgat acccccacga acaatttcgg
    20341 caatataggc tccaccattt agcgaaagtg caatagtagc agctacaaaa tcgttaatcg
    20401 gtgattgatg cccagtcatg ctttcaatga ggtttggcac tccccagaag ataaaggcag
    20461 caacaatcat caaggggata ccacgcacca catcaacaaa gatagtagaa gccatgcgca
    20521 ggttctttga tggggataca gccatcattc caaaaacaat accaataacc aaagcaatgg
    20581 caaaggagat gagtgtcaga ccaagggttg ttccaagccc agccaataat tgcttgtagt
    20641 tattagctaa aagtccataa atagttgact catcggctgt tttgacagat gcctctgaat
    20701 caaggtatct gctgatgatg gcgtcgtatt ttcctgatgc tttaagagca gccaaaccgt
    20761 tgttaaacat ttcgatgagc tcagggttgg ctcctttttt aacagcaaaa ccatactcac
    20821 cagaaggctc tcccttgata ggaatatcaa gcttgtggcc tcgctgaata gcgtacctta
    20881 aaatagcttc atcatccata agcccgtcaa tagaaccaga atttaagcta tcgtacattg
    20941 aggaggcctc atcaaaggct tttagacggt aaccataaat atccttgttg ctttcaagga
    21001 aatcatagga ggctgttcct tttttggcac cgactatttt acccttgagg tccttgtatg
    21061 atttgataga gcttccggat ttgaccccaa ggcgaatgtt tgatgtgtag taggaatctg
    21121 aaaaatcaaa aatctcacga cgtgcaggtg tgatagacat acctgcaata acagcgtcag
    21181 cctgaccagc ttgaacagca tttaaagcag cgtcaaagcc aggattgctg atctcaatgg
    21241 taaagccttg ctgcttagca attgccttga tgaggtccat atcaataccg acatattctc
    21301 cgctgccaat ttgaaattca aagggagcaa aggaggagtc agccacgatt ttataaaccg
    21361 gctttaaagg agtggcctta gcagaggcat cgccagtagc cttgcctgct gtgaccttgt
    21421 cattgctgcc aagccatttt gtcatgatag cttgataggt tccatcagcc ttcatagcgc
    21481 ctaaggcttc attgaagtcg tcaatgagat aatcatagcc gctgcctttt ttgacagcaa
    21541 agccaaagct tccaatagcc tctcccttca tgttgatcgc aagatcctgc ttttggttaa
    21601 tggcatattg aatgacaggc tcgtcgtcca taacagcgtc aatagagcct gttgcaagac
    21661 tgttgtacat caggtcacct gtgtcaaatg ttttaacagt ataaccatac gattttttgt
    21721 atttatctaa gaaggcttga gcagctgttc catttttaac accgactgtt tttcctttta
    21781 gctcgctata tttcttaata gggttagcct ttcttgtagc aataacaatt tttgtatcgt
    21841 aatagggatc tgaaaaatgg aagacctttt gacgagcagc agtgatggtg gtgcctgcca
    21901 taagggcgtc agcttgacca gactgaatgg cattgacagc agcatcaaag ccagggaatg
    21961 tcatattgat attccaaccc tttcgctttg ctacttcatt gatgatgtca acatcaatcc
    22021 ccttatacac ctgatctgaa tccttgaatt caaacggtgc ataagcagta tcagaaacaa
    22081 tatcaattgt ctctgcactt gcaatcccag cagtcatcaa aacaactgac agcattgcaa
    22141 gcatccatgc ttttaatgtg tttttcatac tagtctcctt aataaaaata aaaaatatgc
    22201 ctaattatag cagatttttt tcaaacaagc aaatcatctc ttctttttat gtcataaaac
    22261 ctaacataaa caactaaaat agtcaaaaag ctttgataga gtctttaagt ccttaactat
    22321 gttacaatag ataagagata agatattgag gaccaataaa tgattgataa acgtgatttt
    22381 aaagcattta agctcgtgtc aaaatatgcc ccctcaggag atcagccgca ggcgattgag
    22441 accttggttg ataacattga aggtggtgaa aaagcgcaga ttttactagg agcaacagga
    22501 acagggaaaa cctataccat gagtcaggtg atcagcaagg tcaacaagcc aacgttagtg
    22561 gttgctcata acaaaacctt ggccggtcaa ttgtacggtg agtttaaaga gttctttcct
    22621 gaaaatgctg tcgagtactt tgtatcctac tatgactatt atcagcctga ggcctatgtt
    22681 ccttctagtg atacctatat tgaaaaagac agctctgtta atgatgagat tgacaagctg
    22741 cgccattcgg ccacctcatc gcttttagag cgtaatgatg tgattgttgt ggcttcggtt
    22801 tcttgtattt acggattggg ctcaccaaag gaatatgctg attcagctgt tagcctgcgt
    22861 cctgggcagg agatatccag ggatcagttg ctcaatgccc ttgtagacat tcagtttgaa
    22921 cgcaatgaca ttgattttca acgtggacgc tttcgtgtgc gtggtgatgt ggttgaagta
    22981 tttccagcct caagagatga gcatgccttt cggattgagt ttttcggtga tgagattgat
    23041 cggattcgtg aaattgaaag cctaacgggt aaagtattag gtgatgctga tcatttagtg
    23101 ctttttccgg ccactcactt tgtgaccaat gatgagcaca tggagcagtc tattagcaag
    23161 attcaggcag aattagcaga ccagcttaag ctatttgaag cagaaggcaa attgctagag
    23221 gctcagcgcc tgcgtcaaag gacagaatac gatattgaaa tgctacgtga aatgggctac
    23281 accaatgggg ttgaaaatta ctcacgtcac atggacgggc gttcggcagg agagcctcct
    23341 tataccctgt tagatttctt tccggatgat tttcttatca tgattgacga gagtcacatg
    23401 accatgggac aaattaaagg catgtacaat ggagacaagg ctagaaagca aatgcttgtg
    23461 gattatggct ttcgtcttcc gtctgcctta gacaatcgtc cgcttcgtcg ggaggagttt
    23521 gaaagtcatg tgcaccagat tgtctatgtc tcagcaacgc ctggagatta cgagatggag
    23581 cagactgata cgattgtgga gcagattatc agaccgacag gtctgcttga tccggaggtt
    23641 gaagtccggc caagcatggg acaaatggac gacttgcttg gcgagattaa cctgagggtt
    23701 gaacgaggtg agcgcacctt tatcacaacc ttaaccaaga aaatggcgga ggatttgacc
    23761 gactacctca aggaaatggg tgtcaaggta aaatacatgc atagcgacat caagacatta
    23821 gagcgtacag aaattattcg cgaccttcgt ttaggcgttt ttgatgtctt gattggtatc
    23881 aatctgctgc gtgaaggtat tgatgttccg gaggttagcc ttgttgctat tcttgatgcg
    23941 gataaggaag gcttcctaag aaatgaacga ggtttgattc agacgattgg tcgagctgcc
    24001 agaaatgctg atggtcatgt gattatgtat gctgatcgta tgacggattc catgcagcgc
    24061 gctatagatg aaactgctcg tcgtcgtgcc atacagatgg catataatga agagcatggg
    24121 attattccgc aaaccattaa aaaagatatt cgtgatttaa tcagtatttc cagagcagtt
    24181 gaagcaaaag caacagaagc agagacaaat tatgagtcaa tgacgcggtc tgaaagacaa
    24241 gaagctatta agcaattgca aaaaaacatg caggaagcag cagagctgct ggattttgaa
    24301 ttagcagcac agcttcgtga cctgatctta gagttaaaag caatggatta agacctgata
    24361 agctaagtct ggctgtataa gctaggcttt ttatctgctt ttgagtttgt cctttaggtc
    24421 tgtcttatga tctttggtac cagataaatg agtgatatct tgagcttgat ctacgcaaga
    24481 gctagtgcag ccactagctt cagactactt taatgattta atgaaagatt gattttgata
    24541 agacaattct gatataatgt aaagtagttg gcaaaaatag aaacattaaa taaattttct
    24601 ttttaataat ttaactttta ccttgtcaac aaggctattt tcggatagaa tttcttagta
    24661 cattatttca ctaatacaag aaggtaagta tgttaaaaaa caagtcaaga ctgcgagcta
    24721 ttttcgtttt tgttgggaag atagcgttgt tttacgtgat tttgatgctg ctcgtttatt
    24781 tttttggtta cctagggcat ggtcaaagta attttattta taatgaattt taggagattg
    24841 tctgatggtt aacgatatga ttgaaacaat tgagtatttt gcacaagcac aaccggattt
    24901 tccagtttat gattgcttgg gagagcgccg tagctatggg cagctaaagg aggactcaga
    24961 tagtattgca gcccttattg agagcttaaa gctaggtgaa aaatcacctg ttttagtttt
    25021 tggggctcaa agctatgaca tgctggcttc ctttgtcgcc ttgacaaaga caggtcatgc
    25081 ttacattcct gttgatgttc attcggcgcc agagcgtgtc ttgtctatta ttgagattgc
    25141 tcagccaagt cttatcattg ctattgagga gctgccggtt agtattgatg cgattagggt
    25201 ggttagctta gcagagatag aggcagctaa agcagccaag gcagccttta ccatgaccag
    25261 tcctgtcaag ggagatgaca attattatat tatcttcacc tctggaacga caggacagcc
    25321 aaagggagtg caaatttcgc atgccaatct tttaagcttt accaattgga tgattgagga
    25381 tgctgagttt gctattcctg agagaccaca gatgctggct cagcctcctt attcctttga
    25441 tttgtcggtg atgtattggg cgccgacctt agctttaggt gggacattgt ttgctttacc
    25501 caaggaaatg gtttcagatt ttaagcgctt gtttagcaca attgcggagc tgccgatagg
    25561 gatttggacc tcaacaccgt cctttgccga catggcaatg cttaatgatg atttttgtca
    25621 ggagaagatg ccaaggctga cccactttta ttttgatggg gaggagctga cagtatcaac
    25681 tgcaagaaag ctatttgaac gctttccaga cgcacgcatt atcaatgcct atggtccaac
    25741 agaggcaacg gtggcgttat cagcgatttc aatcactaaa gatatgatag agacttacac
    25801 acgcttgccg ataggctatc caaagccgga ttcgcctact tatatcattg atgaagctgg
    25861 caatgctctg gagccggggc aacagggaga gattattgta acgggtccag cagtttctaa
    25921 gggttatctc aacaatcctg aaaagacagc tgaagccttc tttaccttta atggcatgcc
    25981 tgcttatcat acgggagatt taggatcatt tactgaggac aatgtgttac tttatggtgg
    26041 acgattagac tttcaaatca aatatgcagg ttaccgcatc gaattagaag atgtgtcgca
    26101 gcagctaaac caatcaccgc tggttgaatc agcagtagca gtaccaaggt ataacaaaga
    26161 gcataaggtc caaaatctct tagcttatgt tgtcttgaag gacggggtga gggagcaatt
    26221 tgcgagagat ttggatatta ccaaagccat taaagcctct gttaaggatc atatgatggc
    26281 ctatatgatg ccgtctaagt ttatttatcg tgaaaagctc ccattgacac caaatggcaa
    26341 aatcgatatc aaattcttga ttaacgaggt taatcatcaa tgacgacctt gtttcatcac
    26401 ataccttata tggagcctta tggcaatccg atttattttg tctacctcat cattgctttt
    26461 cttccagtta ttattgggat ctttaagcaa aggcgttttt cgacgtatga aagctttgtc
    26521 agcctgatct ttattttgct catgtttggt ggagagcact atcagcaatt gcttgccttt
    26581 ttagcctatc taatttggca aaccatcagt gttttggctt acaagcacta tcgtcaaaag
    26641 gcaaatgcag cgtgggtttt ctatcttagc attttagcca gtctatttcc tttgatttgt
    26701 gtgaaggtaa gcctcagtct aacgaggtct ttctttagct tcttaggtat ttcctattta
    26761 actttcaaaa gcgttgggat gatcattgaa atgcgtgatg gggttttgac agattttagt
    26821 ctaaaggatt ttctacgctt tatgattttc tttccgactt tttcaagcgg gccgattgat
    26881 cgcttcagaa ggtttcaaga ggcttacacc aagcttccta gtcgtgatgt ttaccttgat
    26941 atgctcaata aggctgtcat gtatctcatg ctgggctttc tgtacaagca tattatctct
    27001 tattgcttgg gtgggctgct attgcccctt gctgaaaata aggctctgac tgtaggtggc
    27061 tactttaata aagagacgat ctatgtcatg tacctttatg ggcttaatct cttttttgat
    27121 tttgctggct actcgatgtt tgcgattggg ttgtcttatt tactggggat taagacacct
    27181 gaaaatttca ataagccctt cttatcacca aatttaaaag agttttggaa cagatggcat
    27241 atgagcctat cattttggtt tagggatttt gtttttatgc gattggtcca tctattgatc
    27301 aagcacaaga cctttaagaa tcgaaatgtg acttcgggct ttgcttacct gatcaacatg
    27361 ctggtgatgg gactttggca tggcttgacg tggtattata ttgcttacgg tctgtttcat
    27421 ggtattggct tgattgtaaa cgacgcttgg cttcgtaaga aaaaggaaat caatcgtcgt
    27481 cggaaaaagc aagggcttaa gcctttgttt gagggtaagg tatttcatgc tttatcaatc
    27541 gtggtcactt tccacgttgt cttgttctca cttctgttat tctcaggctt cttaaatgag
    27601 ctttggttta gcagaccgtt acgttaaaaa aggagagtat aaaaatgtct actaaagaaa
    27661 ctgtaattga cttatttgat cgcttgttta tggaagacgt atcagatatg atggacgagg
    27721 atttgtttga tgctggcgtt cttgatagcc taggaacggt tgagctgatt gtagagatcg
    27781 aatctatctt taacattaag gtgccaattt cagagtttgg acgtgaggac tggaacactg
    27841 ccaataaaat tattcagggc atagaggaat tgcagcatgc ttaaacggct ttggttaatc
    27901 ctaggtcctc taatcatcgc ttttggcttg gtttgtctta ccatattcag ctttcctact
    27961 aagcttagct attcattgcg ccaggaaaag tcaaatgcag tggcaatcaa tgatagctcc
    28021 tttaaaaacg gcttgattaa aaggcaggcc ttgtcagatc ctaactactg ttttgttccg
    28081 ttttttggct ctagcgaatg gagtcgcatg gatagcatgc acccatcagt gcttgcagaa
    28141 cgctacaagc gctcctacag accgttttta attgggaaaa gaggctctgc ttccttatca
    28201 caatattacg gcatgcagca gatttcacag gaaataactg gaaaaaaggc agtctttgtc
    28261 gtgtccccac aatggtttac cccccaaggc attgatcctg gtgcggttca attgtatcta
    28321 tctaatagtc aggtgattga tttcctctta aaagcaaagg ctagtcataa ggaatcacaa
    28381 tttgccgcta aaagaatgct ggacattaat ccgggagttg ctaaatcaga gcttttaagg
    28441 aaaattagtc aaggcaaggc cttgagtaga tgggacattc gtctgctcaa atggcagcag
    28501 gagctgtcct taagagagga gtccttgttt agcttccttg gtcgttcaac aaactatgag
    28561 gataggattt tgcctcgtgt taaagggttg cctaaaacct tttcttatga gcgcttgagc
    28621 gagctagcag ccagacgggc taaggaagga acttcaaata atcgctttgg catcaaaaat
    28681 gctttttatt ctaagcgaat tgcaccgcaa tttcctcttt ataagaattt tcagtgccgt
    28741 aataattaca ctgtgtcacc tgagtacaat gattttcagc tggtattgtc agaatttgca
    28801 aaacgtaaaa cagaggtgct tttcgttatt acacctgtta atcaagcgtg ggcaaattat
    28861 acaggcttaa accagaggag gtatcaaaag gctgtcagaa aaataaagca tcagttaacc
    28921 tcgcagggct ttactcgcat tgctgatttt tccagaaatg gcggagacaa gtattttatg
    28981 gaggatacca ttcaccttgg ctggaatggc tggctagcct ttgacaagga ggttgttcct
    29041 ttcttagagg atcaaacacc accatctgaa taccaactgg atccttactt cctatcaaag
    29101 gactgggcag atagaacagc aggattttag ggtcaataga ccattagaaa atgaggatta
    29161 gaattgttaa tgagtatcat cgtcatattg cttattttag ccattgctgt tttagtgatt
    29221 gagtatggtc aaaagcggtc cttttctagc tggctgcttg aaaagatgtt tgattatcgt
    29281 aagtataagc tctctaaaaa ggctgatgac tatgaaggaa ttgagacgca aagacgtcgt
    29341 cgcattccct accacttgga taatccagag gcggtattgg ggattcccac cacagaatat
    29401 acgattgatg gcatgcaggt ttttgtgatc aatgaccaag attctcagga tcagccagtg
    29461 atttactatc tttatggtag tgtctatttg cgtcgacctg agacatttca ctttaaaacc
    29521 attaagcatt tgatccattt aaccaatgcc aagctggtgt tcccaaattt tgagaaggcg
    29581 ccttatgtca cctataagga gatttaccca aagcttgcta aaacttatca ggagctttgt
    29641 ctagccaatg gcgctgccaa ggttagcatt attggtgact cctcaggtgg tggcatggcc
    29701 ttagccttgg cgcaatacct aagagatacc caaactgcac cacagccaaa gcaattaatc
    29761 ctgttatctc cttggttaga tgttagcttt gctaatcagg attataagca ttttgaagca
    29821 gtagaggctt atttagatgc taggcggctt cgagacattg gtgaattgtg ggcaggcagt
    29881 ccagaagaaa tgcggtctcc gtatgtcagc ccattatatg gcgattatca tgacctgcca
    29941 aagattgtca cttttgtcgg gacaaaagag attttttacc cagatattat gaccctgcat
    30001 gagcgcttga tggagcaagg gcacttaaat cagctcgtta ttgctgagca gatgattcat
    30061 gcttatgcga tcttcccgat acgagaggca aggcaggcgc gcaagcagat tgccgagctg
    30121 attttaaaga aggagtgatt gttgctatag gagtcagtta gccttgcttg tctgatgagg
    30181 cttgggcttg agatttctag agaagcttta aggcctttac ttgggctgtt aatgctcatt
    30241 aaagaggatt ataggcttta tactagggct taggattgct gttttgctat tcaataatat
    30301 tagtttagac ttgattgagg aaaggctagt tttagttatg gtcctcaatc tttttttgat
    30361 ggtaaacatg tcaagacagt ttacttgcta gggtaataat cctgtgctca tttcatgagt
    30421 ggctattttt atcctaagct tggtggtgga aaaatcagat taaaaaatat gaaatttgct
    30481 attgacagct gtaagcgatt gcattataat aaacttaact taaacgttta agttaagttg
    30541 aataagctga tttgatcatg cactgcctaa atgcaatcaa taatctcaaa gcatttggtg
    30601 tagtctagta atcaatgagg cagtttatta cggttataca atatttattt agttcatccc
    30661 tttaggaggt aaatagctat ggcgtgggat tggaaaaaag caggtgttgt tggagtagtg
    30721 tcattggctt cgatcatggt attaagtgct tgtagcggag gacatcaaaa agaggctaag
    30781 caaaaagacg acaataccat tgtagtttca gttgatgagg gctatgcaga ctacatcaaa
    30841 gagattaaga cagcctttga aaaggacaat aaggtcaagg tcaaggtcaa aaaggaaggt
    30901 atgattgata cgctagataa gctatctact gatggaccga caggtgcttc accagatgtc
    30961 tttttagcac catatgaccg ggttggtggg cttggctctg aagggcaaat tgctgaggtg
    31021 agcttaggca atgctgacca gtttgatgac actgttaaaa agctagtcac cataaatgga
    31081 aaggtttatg gggcaccaga tgttattgag accttagtga tgtattataa caaggatttg
    31141 gtatcagagg ctccgaaaac ctttactgac attgaagagc taaataagga tcctaagttt
    31201 gcctttgctt ctgaagacgg taagtctgta ggctttcttg ctaagtggac agacttctat
    31261 tatggctatg gcttgattgc aggctatggg gcttatgtat ttggagataa gggaactgat
    31321 ccaaaggatt taggtattgg taatgctggt gccattgaag gcttagacta tgctaagaaa
    31381 tggtatagcg tatggcctca aggcatgcag gatactcaaa aggctggaga ttttattaca
    31441 gagcaattca cctctaaaaa ggctggtgtg attattgatg gaccttgggc tgctgcctca
    31501 tttaaggagg ctggtgtaaa ctttggagtg gcacaaattc caagcttacc taatggcggt
    31561 agctatcaag cctttggtgg tggtaaagca tgggtgattt caaattattc taagaataaa
    31621 aagctggcac agcaattcct tgattatgtg acaaatgaga aaaaccaaaa agccttttat
    31681 gataagacac aagagatccc tgccaatcta gctgctcgca gctatgctgc agaacaagga
    31741 aatgaattga caaaggcggt tattgggcaa ttctcaaatg ctcagccaat gccaaatatt
    31801 ccagaaatgg cagaagtttg gggaccaggt gcgaacatgt tctttgaggt agcagcaggc
    31861 aagaagactc ctgccaaggc tgctaaggaa gcagctaaaa ccattcaaga ggctattgca
    31921 caaaaataca ctgaataaca taaaaaggga ggctgggata aaggtatcct agtctccatc
    31981 ttgttaccta tagtatcaga gtgggcgatg aggagataat aataaaaagt agtagtgact
    32041 agcttgtctt gtttcccatc ttgtcctaat aagagtatct gataagactg atgaacctag
    32101 ggaggaaaaa atgaacacag ccggaatact gcatattcca gattctagat attgctttgc
    32161 cttatcaaca aaggagcttg tgattcggtt gagggttgca aaggaggata acgatatagc
    32221 ggtgacgctg gtttatggac ctaagtatca ttatcatgag tatcaaaaag aactggcgat
    32281 gtatgctgct tataccgatc atacccatac ctattatgaa atcaccttaa gtcttgatga
    32341 tgttagattg gcctatattt ttaagcttga gcaatctggt cacacctatt actttagtga
    32401 ggatggcttg accacaagct atgatttttc aaatggcttt tacaactttt ttcaaatgcc
    32461 ttatattaat gctgtagacg ttcatcagac tgtcccttgg gtgcacaatg ctgtttttta
    32521 tcagatcttt gttgatcgct ttcatcgtgg tgactttgaa aaggacgata gctatattaa
    32581 tatggcttgg ctggataggc caactcctaa tagctttgcc ggaggggatt tgaaggggat
    32641 tacagataag ctggaatacc ttgaggatct tggtattaat gtcatttact tgacaccgat
    32701 tttcaaatcc atcagtaatc acaaatatga tattagtgac tactatgcta ttgacccgat
    32761 gtttgggaca tcgcttgatc tccagcaact aataaacgag gcccaccaaa gagggattag
    32821 aattatttta gatgctgttt tcaatcatgc tagcagtgat tgcgagccat ttcaggacgt
    32881 tttggcacat ggtagtgctt cttcattttt tgattggttt atgattcaag gagatcatcc
    32941 ttctgtagag ctagctaatt acgaaacctt cgctgattgt cactacatgc ctaagtggaa
    33001 tacctcgcat caggctgttc aggattattt gattgagatt ggtctttatt ggatcacaga
    33061 gtatcatatt gatggctggc gattagatgt ttctgatgag gtatcgcatg atttttggag
    33121 acgctttcga aaggctgtta aggcagtcaa atcagatgcg atacttattg gagagaattg
    33181 gcatgatgct tatccctacc ttcaaggaga ccagtatgat ggtattatga attacgcctt
    33241 taccaaggct tgtctcgatt attttgcatt tgatgcgatt agctcacagg aaatggctga
    33301 aagattgtcg catattttaa tgagaaatac ttggcaggtc aaccagatga atctgaattt
    33361 actggattcc catgatacgc atcgcttctt gactcaggtg aatggctcta aggacaaatt
    33421 attggctggc ttagcccttt tagttacctt tatgggcata ccatgtattt actatggaac
    33481 agagcttgcg atggagggag gttatgatcc tgactctaga cgtagcttta attgggacag
    33541 cagcacttgg gatatgagct tttggaatca ggttaaggac attatcagcc tgcgtcgtca
    33601 tgcggttatc caatttggaa gcatttcgat aacctcccat gatgactgcc tttgcgtaaa
    33661 gcgtgaatta aacggtcaat cgataagatt gctggttaat aatggcgtta agccatatcc
    33721 tattgagaaa ggaggttctg tgcttgtttc taatggtgta gataaagaga catttgagct
    33781 actccagaac gggtttgttg ttagctatta atatggcgtt ttatcaaagg aggttaagga
    33841 tgaagcgtat tactttaaca tgtcgtaaag cattaacagt agctatggca gcggttacct
    33901 tagcaatgtc aactaacagt gtctttgcta ttgaaaatac tgcggtgtct aataaggctg
    33961 atttttctac tgacacgatt tatcaaattg tcaccgatcg ttttcatgat ggtaatgctg
    34021 ctaataatgg aaatacagat gtatttgata aaaatgatcc taaaaaatat catgggggtg
    34081 attgggcagg tatcattaag aaactagaag atggctactt aaccaattta ggggtatcag
    34141 ctatctggat ttcatcacca gttgaaaaca ttgataccat tgacccttca aatggcagtg
    34201 cagcctatca tggctactgg gcaaaggatt ttttcaaagc aaacagtcac tttggaacaa
    34261 tggaggattt taaaaagctc attcaggtgg cacatggcaa aaacattaaa gtagttattg
    34321 attttgctcc taatcatacc tcaatagcag aatataatgg cttaaccttc cctgaggacg
    34381 gtgctttata taaggacggc cagctggttg gtaaattcag tcatgatgat caaaagattt
    34441 tcaatcatga atcatggact gatttttcaa cttatgaaaa tagcatttat cattccatgt
    34501 atggcttggc agacttgaac aatctgaatc caacagttga cgattatctc aaagaggcta
    34561 ttgataaatg gttagaaatg ggcattgatg gtattcgtgt agatgcggtc aagcatatgt
    34621 cacaaggctg gcaaaaaaat tggttgagtc atatctatga gaagcataat gtattcgcct
    34681 ttggggaatg gtttgctgac ggttctttta atgatccatt gatgactaaa tttgctgata
    34741 ctagcggcat gagcctgctt gattttaggt ttgctaattc tgttaggcgc ctgtattctg
    34801 atttatcagc gaaaatgcaa gatttttaca atatgattgt agctacggaa aaagagtaca
    34861 aggaagtttc agatcaagtg actttcattg ataaccatga tatgacccgc tttgctactc
    34921 tagtcaatca taatcagaca gctgttaatc aagcctatgc tttactgcta acatcgcgtg
    34981 gtgttccgaa tctttattat ggttcagagc agtatgctac aggtgctaac gaccctgaaa
    35041 atcgtggtga tatgccaacc tttgataaga attccactgc ttatcaggtg attagcaaac
    35101 tagcaccact gcgtaagaaa aatcaagccc tggcttatgg tacaacacag cagcgctgga
    35161 ttaatgatca ggtcttggcc tttgaaagaa aatttggaaa tgacgttgct ttagtggctg
    35221 ttaataagga tcaaacaaat ggctacacaa ttagtggcgc taaaacggct ttaccagctg
    35281 gtaagtatgc tgatgaatta ggtggcttac tgggcggaaa ggaattaacg gtatcagctg
    35341 atggtaatgt tgaggcattt gagttaggtg cgggtcaggt tgcagtttgg acctttaaag
    35401 ggcaacatga gacaccgcag ataggagacg tagacgcttc gtttggcgtt gcaggaaata
    35461 ctgtctctat ttcagggcaa ggatttggta gtgctcaagg tcagcttcat tttggtgata
    35521 gcaaagcaga tattgtgtca tgggacgata ccttgattca atttaagata cctgctgtag
    35581 ctgctgggaa ccatgatatt aaggtgacca catctacagg acaaagcagt agcccttaca
    35641 aagcctttga agtgttaaca gataagcaaa ttccagtaag attggtggtc aataatttca
    35701 acactgtatt aggtgagcag ctttatatcg ttggtgatgt ggttgagctt ggggcaaatg
    35761 ataatcataa agctttaggg cctattttta atgcaacaca gtcaattgcg cagtacccaa
    35821 attggttcta tgatgtcaat ctgcctatta acaaaaccat taactgtcat cttgtaaaga
    35881 aggatagttc tggtaaagta ttgtggacta gtccagaaac ctataccatt aaaactgata
    35941 gcaaggctca aaccatttca ttgaaaaaat agttgcgtta tctgtgatgt tatttaatac
    36001 tctatgaagg aggagaacca taaaagggtg atagagagga atgacaaatg cttaagaatg
    36061 aaaaaatgaa gaatccacaa aaagccatgt ggctttcaat aatccctggt ctggggcaac
    36121 tctacaatac tcaaaaggta aaaggcttta ttttgcttct tgtgttttta ggtgagctgc
    36181 tagaggcttt ctttgttggt attccggctc ttgctggctt gtacagcctt ggtagtgtac
    36241 caatggagga tcattcccta ttcttattga ttaagggagc tatgcagctt atcctatttg
    36301 ccttgttttt gatctttcat ttggctgcta tgcgagatgc tagactagtg gcaagggaga
    36361 tcaatgcagg ccatagcatt tcattaacct taaaggagat ggtacaatcc atctatgaaa
    36421 agggctttcc ttatttgctg attattccag cctacttggc catggccttt gccattgttt
    36481 ttccggtgct tgttacttta ttaattgcat ttacaaacta tgattttagg catattcctc
    36541 cctataaatt attagattgg gttggcatta agaattttaa aagcatttta gagcttagca
    36601 cctttaagtc agcctttggc tctgtgctgt catggacctt gatttggacc ttggcggcaa
    36661 cgagtctcca gattgtgata ggaatagcga ctgctattat tgccaaccag tcctttgtga
    36721 agtgcaggcg catttttggg gtgattttct tgctgccttg gggggtgcct gcttttatct
    36781 cgatcatgag ctttggtaat ttctttaatg attctatcgg tgctatgaat gttcaggtct
    36841 taccattttt agaaaagttt gtgccatttg cagattttgg gattatccca tggaagacag
    36901 atcctttttg gacaaaggtt gcggtgatta tggttcaggg ctggctgggc tttccttata
    36961 tttatatttt ggtgtctggt attttacaat caattcctgc tgatttgtat gaggcagcaa
    37021 cggttgatgg tgcaacagcc ctgcagaagt ttcgccaaat taccttgcca atgatctttg
    37081 ctgtcgcagc cccgacctta atctcgcagt atacctttaa ttttaataac ttctccatta
    37141 tttatctctt taataatgga ggtcctggta cagttggcgg tggcgcaggg tcgacagata
    37201 ttttgatttc ttggatttac aagctgacca cacaaacgtc accacagttt tccattgctt
    37261 cagcggtgac cttaatcatt tccttgattg ttatttctgt atcattgata acctttaaaa
    37321 aattcaaagc ctttgacatg gaggatcgct aaatgggtag gaattatttg ccacagtcag
    37381 tgaagaagaa gcgcttgtta gctcagctgt tgacttacag ctatttgcta atcctgtcga
    37441 tcatcatctt atttccaatc ttggtgaccg ttagctcagc ctttaggcca ggaaatacaa
    37501 ctgcctttag ctttcatatt gatgggcctt ggaccttatc aaactttgag acactctttc
    37561 aggacaccta ttacttaaga tggtactgga acacgttagt tgtcgccttt ttcacgatgc
    37621 tgatccaggt gacagtcatt acgctgacag gctatgctta cagccgttat cacttttttg
    37681 ggcgtcaaaa gagtttggtc tttttcttag tggttcagat ggttccgaca atggctgcct
    37741 taacagctta ttttgtgatg gcttggttgt ttaatgctct gaatcactat tggttcctca
    37801 ttctgattta tgttggagga ggcattccga tgaatgcttg gttgatgaag gggtattttg
    37861 atactgtgcc ttatgattta gatgagtcag ctaagctaga tggctctggt cactttagga
    37921 ccttctacca aattgtattt cctctggttc gtcctatggt tgctgttcag gccctatggg
    37981 cctttatggg gccatttggt gactttatgc ttgctaagtt tctcttgcgt gaacaggagc
    38041 attacaccgt agcggtaggt cttcagtcat tcatcactaa cgacgctagg gatcctaagg
    38101 tcacattgtt tgcagccggg gccattttaa ttgcagtgcc aatttcagtg ctattcttct
    38161 ttttacagaa gcattttgtt tcaggcttaa ccaatggtgg aacaaagggt taatttatct
    38221 ttcaaggagc ctttatcatg actaatgatc gatttcctat ttcttacaca accattattt
    38281 tttctcctaa aatgatattt gctcgttgca gtgccttttt gtggtggcag aatgtgattt
    38341 tagtgatctt tctaaatgct ctggtgttaa tgccgatcac gctgcattat gcaagcttga
    38401 agagctatcc cttagagcac atagttagta atggtttaga ctccttgaca gaaaaaacct
    38461 atcatgcctt gacacaaggc actatttggc atgatcgcta tgatggaaaa acagtcctta
    38521 tagaggatac tgatgctgtt gttgctgtat tgccaacacc agaaatagta gaagagctaa
    38581 agaaagatca aagaagccag ctgatattaa cagaaacctc atggatttta agctttcctg
    38641 atggtcaaag gctaactgct aaggttaaag gcaacaagga aaggctaacg cgcttaacct
    38701 ctctagaggc tgtcaaggcc tttgttaatc agcaatggta caatagcaat cgtgccgctg
    38761 tgcttgcctt tttgctgcta gtggctagca gtgtggtcta tctaggagcc ggtttagtga
    38821 tcggaattgg ctcgttatca ctgttattaa caagatctgc tagattattt tcactcaaga
    38881 gctactcaga atgcttgggt ttgctagtga attgctttgg acttcctacg cttttagcag
    38941 tgcttataag tttttgggtg cacaatccta ttgttatcat gaatagtcag gtctttggca
    39001 cactgctcat gctggttcta gtcttttaca aaactcagtt tagagatgag gagcaagcac
    39061 tagcttagcc cttgctgaca tcaaaaaatc cctccc
//
LOCUS       DARYXW010000008        37882 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.008, whole genome shotgun sequence.
ACCESSION   DARYXW010000008 DARYXW010000000
VERSION     DARYXW010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37882)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37882)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37882
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.008"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(<1..191)
                     /locus_tag="TV191_000328"
     CDS             complement(<1..191)
                     /locus_tag="TV191_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEL1506878.1"
                     /translation="MSQTYERIMVAIDGSHGSELAFHKGVNVALRNGAALILTHVVDT
                     RALQSVATFDSYIYDKLEQ"
     gene            478..1692
                     /locus_tag="TV191_000329"
     CDS             478..1692
                     /locus_tag="TV191_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEL1506879.1"
                     /translation="MKIIEKSSKLEHVAYDIRGPVLDEANRMIANGEKILRLNTGNPA
                     AFGFEAPDEVIRDLILNARSSEGYSDSKGIFSARKAIMQYCQLKGFPDVDIDDIYLGN
                     GVSELISMSLQALLDNGDEVLVPMPDYPLWTACVSLGGGHAVHYLCDEEAEWYPDIAD
                     IKAKITERTKAIVIINPNNPTGALYPREVLEEIVAIAREHQLIIFADEIYDRLVMDGG
                     EHIAIASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKRHVRGYIEGLNMLANMRL
                     CSNVLAQQVVQTSLGGRQSVDELLLPGGRIFEQRNFIYQAINAIPGLSAVKPKAGLYL
                     FPKIDRNMYRIDDDEEFVLQLLKQEKVMLVHGRGFNWKEPDHFRVVYLPTVEELADVQ
                     EKITHVLKQYKR"
     gene            1864..2646
                     /gene="codY"
                     /locus_tag="TV191_000330"
     CDS             1864..2646
                     /gene="codY"
                     /locus_tag="TV191_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001133183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEL1506880.1"
                     /translation="MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNAC
                     IINGGGSLLGYAMKYKTNTDRVEEFFETRQFPDAYVKAASRVYDTEANLSVENELTIF
                     PIESKDIYPDGLTTIAPIYGGGMRLGTLIIWRNDNEFSDDDLVLVEISSTVVGIQLLN
                     LQTENLEETIRKQTVVNMAINTLSYSEMKAVAAILSELDGNEGRLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVINEGIFDKLKEF"
     gene            3263..3820
                     /locus_tag="TV191_000331"
     CDS             3263..3820
                     /locus_tag="TV191_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEL1506881.1"
                     /translation="MKALISIDYTNDFVADDGSLTAGAPAQVISEAMASVVEAAFEAG
                     YYIFFAIDAHEEGDSFHPEAALFPPHNIIGTRGRDLYGPLMTVYTRYQQDQRVFWLDK
                     RHYSAFSGTDLDIRLRERGVTTLVLTGVLTDICVLHTAIDAYKLGYKLEIITSAVASN
                     STENHQWALNHCRTVLGAKLLDRLS"
     gene            4294..4596
                     /gene="gatC"
                     /locus_tag="TV191_000332"
     CDS             4294..4596
                     /gene="gatC"
                     /locus_tag="TV191_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008086915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEL1506882.1"
                     /translation="MKISEEEVRHVAALSKLSFSESETTEFATTLSKIVDMVELLNEV
                     DTTGVAITTTMADKKNIMRADIAEAGVDRKLLFQNVPEKENHFIKVPAILDDGGDA"
     gene            4596..6062
                     /gene="gatA"
                     /locus_tag="TV191_000333"
     CDS             4596..6062
                     /gene="gatA"
                     /locus_tag="TV191_000333"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEL1506883.1"
                     /translation="MSFNHHTIEELHELLVAKDISAVELTKATLEDIKAREEAVGSFI
                     TIACEAALKQAAALDAKGIDPDNVMSGIPLAVKDNISTKGILTTAASKMLYNYEPIFD
                     ATAVANAYDKDMIVIGKTNMDEFAMGGSTETSYFKKTKNAWDHSRVPGGSSGGSATAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGVVGLKPTYGAVSRYGLIAFGSSLDQIGPFAPTV
                     RENAQLLSVIAGSDRKDSTSAPVQIADYTIKIGQDIKGMKIALPKEYLGEGIDPKIKE
                     TVLAAAKHFEKLGAIIEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGFRAADA
                     KSLEDIYVKTRSQGFGDEVKRRIMLGTFSLSSGYYDAYFKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPTAAFELDTLNHDPVAMYLADLLTIPVNLAGLPAISIPAGFADGLPVG
                     LQLIGPKYSEEVIYQVAVAFEATTDYHKQQPMIFGGDR"
     gene            6062..7501
                     /gene="gatB"
                     /locus_tag="TV191_000334"
     CDS             6062..7501
                     /gene="gatB"
                     /locus_tag="TV191_000334"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEL1506884.1"
                     /translation="MNFETIIGLEVHVELNTNSKIFSPSSAHFGEDPNASTNVIDWSF
                     PGVLPVMNKGVIDAGIKAALALNMSIHQHMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIDITLEDGSTKKIRIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEIIQYTGISDVKMEEGSMRVDANISLRPYGQEAFGTKTELKNLNS
                     FSNVRKGLEFEVERQAKILRSGGVIRQETRRYDEASKGTILMRVKEGAADYRYFPEPD
                     LPLFEIDDAWIEDMRAELPRFPADRRASYINALGLSAYDAGQLTATKALSDFFEQAVA
                     LGGDPKQVSNWLQGEMAQFLNAEGKTIDQIALTPENLVEMIAIITDGTISSKIAKKVF
                     VHLAKHGGSARAYVEKAGLVQISDPAVLIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQIAQQLLAQELQKLLD"
     gene            7730..8674
                     /locus_tag="TV191_000335"
     CDS             7730..8674
                     /locus_tag="TV191_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEL1506885.1"
                     /translation="MSRNGKGSTMILLAGIAWGLSGVSGQYLIAHGVGINALTSLRLI
                     ISGLVLSAMAYVRQREAVISLLKDKRLLRELLIYSLFGLTLNQYAYLLAIRYSNAGTA
                     TVLQYLSPILVLVYLSFKSRRLPAVGESCAICLAILGTVIMACHGDLSHLAINPIGLF
                     WGLFAAVTYAYCVIKPAKLIADWGSLLIVGLAMLMGGVIFPILTRAWQYPLAMTYGNL
                     RALFGIIGIGTIFAYTFFLKGASIIGPIKATLLASIEPVASVCFAIILMKEIFHPIDL
                     LGMALILIAVLVISLRDLLLTKRKKQLALNIKRPPSSD"
     gene            8725..8964
                     /locus_tag="TV191_000336"
     CDS             8725..8964
                     /locus_tag="TV191_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEL1506886.1"
                     /translation="MVWSLIVGAIIGMVAGRITEKSHSMGCFTMTAAGLIGSAVGQKL
                     FGDWGIQLAGMAVFPSILGAAIVIIVASALFGKKQ"
     gene            9161..10276
                     /locus_tag="TV191_000337"
     CDS             9161..10276
                     /locus_tag="TV191_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KxYKxGKxW signal peptide domain-containing
                     protein"
                     /protein_id="HEL1506887.1"
                     /translation="MRKTEGRFRTWKSKKQWLFAGAVVTSLLLGAALVFGGLLGSLGG
                     SSHQARPKEQPVSSIGDDDKSHKSSSDSMVSRPPKKDNLQPKPSDQPTNHQHQATSPS
                     QPTAKSSGHHGNQPQSLSVNSQGNSSGQASEPQAIPNQGPSQPLGLRGGNSSGSGHHH
                     QPQGKPQHLDLGKDNSSPQPQPKPQGNSPKLPEKGLNGENQKEPEQGERGEAGPPLSG
                     LSGNNQGRPSLPGLNGENQKEPEQGERGEAGPPSTPNLEGNNRKNPLKGLDGENKPKE
                     DLDGKGLSGENDESPKLKDEHPYNHGRRDGYRVGYEDGYGGKKHKGDYPKRFDESSPK
                     EYNDYSQGYNDNYGNGYLDGLADRGGKRGYGYSYNPD"
     gene            10540..10806
                     /locus_tag="TV191_000338"
     CDS             10540..10806
                     /locus_tag="TV191_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003067640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEL1506888.1"
                     /translation="MKAIITVVGKDNQGIVAGVSGQIAALGLNIDDISQTVLDDYFTM
                     MAIVSSSEKQDFAHLREVLQAYGKQLQVTINIQSAAIFDAMHNI"
     gene            10821..12158
                     /locus_tag="TV191_000339"
     CDS             10821..12158
                     /locus_tag="TV191_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEL1506889.1"
                     /translation="MDIRQVRETVEMIEEQHFDIRTITMGISLLDCIDSDIDRAAAKI
                     YQKITTKAANLVAVGDDIAAELGIPIVNKRVSVTPIALIGAATDAEDYLSLAKALDQA
                     ACDIGVDFIGGFSALVQKGYQKGDKILIESIPQALAQTQKVCASVNVGSTRSGINMTA
                     VADMGRIIKETAKASEIGAAKLVVFANAVEDNPFMAGAFHGVGEADTVINVGVSGPGV
                     VKRALEKVRGESFDVLAETVKKTAFKITRIGQLVGQMASERLGVGFGVVDLSLAPTPA
                     VGDSVARVLEEMGLEIVGTHGTTAALALLNDAVKKGGVMACNRVGGLSGAFIPVSEDE
                     GMIAAVQGGSLNLEKLEAMTAICSVGLDMIAIPEETPSETIAAMIADEAAIGVINQKT
                     TAVRIIPKGKEGDMIAFGGLLGTAPVMAVNPHSSADFIARGGQIPAPIHSFKN"
     gene            12233..12940
                     /locus_tag="TV191_000340"
     CDS             12233..12940
                     /locus_tag="TV191_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEL1506890.1"
                     /translation="MTKTRLYIVRHGKTMFNTIGRAQGWSDTPLTKAGEEGIRELGLG
                     LKAAGIPFKAAFSSDSGRTMQTMEIILRKSENEFLPYTRDKRIREWCFGSLDGAYDSE
                     LFLGVLPRTKAFENRDNLRDVPYSELAESIVEVDTANWAEPWEVLSKRIYEGFEAIAL
                     AVENAGGGNAIVVSHGMTIGTFMWLIDPDREKQYIDNGSVTVVEYENGQFTIKTIGDM
                     SYRYRGREIIESIRDEE"
     gene            12930..13673
                     /locus_tag="TV191_000341"
     CDS             12930..13673
                     /locus_tag="TV191_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HEL1506891.1"
                     /translation="MKNNTIRVLLQALVVLLFLSGVYLFIKPEKQAVGPKANQTVPAP
                     KAAKQAKKTTDLPKVSTTDWQLVLVNRDHPQEEMSPELVEINGIPIDKRIEQETADFL
                     AAAQTIEPQEHLIAGYRSVVQQEELYQSYIAQELANDPSLTQEAAEALVRKYAQPAGT
                     SEHQTGLAIDMSTVDNLNASDPKVAQEIQKIAPQFGFILRYPKGKQTSTGIEYEDWHY
                     RYVGKASALYITAHSLSLEEYLTRLKEKK"
     gene            13670..14242
                     /locus_tag="TV191_000342"
     CDS             13670..14242
                     /locus_tag="TV191_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL1506892.1"
                     /translation="MRKRLKFSYFLVFLVFIMVALIGPLLFNAKGTSASQEMSVPYTE
                     RQFIQLVAKEVKPLAKNYGIRPSILIGQIILETNYGRTLLAAKYHNLFSLQPAPGQAS
                     ISLKKQAASKHKTAYAIYRDREDSIRAYLSWLSQGTGEEKKLYQSLATEKGYKKPAKS
                     LQTYRYSDDKGYAQRLVQLIEARGLTSYDD"
     gene            14692..15726
                     /gene="hrcA"
                     /locus_tag="TV191_000343"
     CDS             14692..15726
                     /gene="hrcA"
                     /locus_tag="TV191_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015911815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEL1506893.1"
                     /translation="MITERQSNILNLIVDLFTQTHEPVGSKALQSLIASSSATIRNDM
                     AKLEKLGLLEKAHTSSGRMPSAAGFKYFVEHSLNLGSIDEQDLYQLVKAFDFEAFKLE
                     DVLLRASQMLSDTTGYTAAILDVEPARQRLTGFDIVQLSSHDALAVLSLDESKPLTVQ
                     FAIPKNFMNRDLLVLKGIVADRLLGKDVMTVHYKLRTEIPQIVQKYFTVTDNVLDLFD
                     YIFVGLFRETIFVSGKVAALDYAGLATYQFLDEEQRLALSIRQSLSEEEMATVQVADS
                     SEPALANVTLLTYKFLIPYRGFGLLSLIGPVDMDYRRSVSLINVIGQLLAVKLRDYYR
                     YLNSNHYEVH"
     gene            15771..16340
                     /gene="grpE"
                     /locus_tag="TV191_000344"
     CDS             15771..16340
                     /gene="grpE"
                     /locus_tag="TV191_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEL1506894.1"
                     /translation="MSKKPKEELKDQEDILDEAAEEAVEPVEEADQSAELIADEAAEE
                     PSELELALQRAEDFENKYLRAHAEMQNIQRRANEERQSLQRYRSQDLAKKILPSLDNL
                     ERALAVEGLTDDVKKGLEMVQESLVQALKEEGIEEVPVEAFDHNLHMAVQTLPADDDH
                     PADSIAQVFQKGYKLHERLLRPAMVVVYN"
     gene            16745..18574
                     /gene="dnaK"
                     /locus_tag="TV191_000345"
     CDS             16745..18574
                     /gene="dnaK"
                     /locus_tag="TV191_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEL1506895.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVAANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLATAGDNKLGGDDFDQKIIDFLVAEFKKEN
                     GIDLSQDKMALQRLKDAAEKAKKDLSGVTQTQISLPFITAGAAGPLHLEMSLSRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQHIVIKSNDGLSEEEIERMMKDAEANAEADAKRKEEVDLKNE
                     VDQAIFATEKTIKETEGKGFDTERDAAQTALDELKKAQESGDLDDMKAKLEALNEKAQ
                     ALAVKMYEQAAAAQQAQAGAEGAADTGSTNSGDDVVDGEFTEK"
     gene            18731..19867
                     /gene="dnaJ"
                     /locus_tag="TV191_000346"
     CDS             18731..19867
                     /gene="dnaJ"
                     /locus_tag="TV191_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015911812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEL1506896.1"
                     /translation="MNNTEYYDRLGVSKDASADDIKRAYRKMSKKYHPDINKEPGAEQ
                     KYKDVQEAYETLSDSQKRAAYDQYGAAGANGGFGGGAGGFGGFDGGGFGGFEDIFSSF
                     FGGGGMRNPNAPRQGDDLQYRVNLSFEEAVFGTEKEVSYHRESTCSTCAGSGAKPGTS
                     PTTCRKCHGSGVINVDTQTPLGMMRRQVTCDVCHGSGQEIKEPCHTCHGTGHEKKVHK
                     VSVKIPAGVETGQQIRLQGQGEAGFNGGPYGDLFVILNVLPSKQFERNGSTIYYSLNI
                     SFVQAALGDTVDIPTVHGDVAMSIPAGTQTGKVFRLKGKGAPKLRGGGQGDQHVTVNI
                     VTPTKLNEAQKEALKAFAEASGEKPIAPKKKGFFDKVKDALEDI"
     gene            20187..20978
                     /locus_tag="TV191_000347"
     CDS             20187..20978
                     /locus_tag="TV191_000347"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEL1506897.1"
                     /translation="MTFQNIIFELEEDLAILTLNRPEVSNGFNIPACQEILEAIRLVK
                     DNPSLRFLVIKAKGKVFSVGGDLVEMQNAVERDDVQSLVRIAELVQDISFAIKQLPKP
                     VILCADGAVAGAAFNIALAVDFCIASTQTKFIQAFVNVGLAPDAGGLFLLTRAVGLNR
                     ATHLVMTGEGVTAEKGLEYGFVYRAAESDKLDKTCSQLLKRLRRGSSNSYAGMKSLVW
                     QSFFAGWEDYAQKELAIQEELAFKEDFKEGVRAYGDRRRPNFRGK"
     gene            21058..21492
                     /locus_tag="TV191_000348"
     CDS             21058..21492
                     /locus_tag="TV191_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEL1506898.1"
                     /translation="MEYNKINQYLVDIFNRILVIEEMSLKTSQFNDVSLKEMHTIEII
                     GKYQQVTPSDIARELMVTLGTVTTSLNKLELKGYIERTRSSVDRRVVYLSLTKKGRLL
                     DRLHARFHKNMVGHVIADMNEDEMQALLRGLGNLHQFLEDLV"
     gene            21492..22466
                     /locus_tag="TV191_000349"
     CDS             21492..22466
                     /locus_tag="TV191_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEL1506899.1"
                     /translation="MVFSKISQVAHYTPKQVISNDDLSQIMDTSHEWISSRTGIEKRH
                     ISTVEMTSDLAIRVAEQLLAGSGYDATALDFIIVATISPDASMPSTAAKVQAAIGATN
                     AFAFDMTAACSGFVFALAMADKLIASGAYQRGLVIGAETLSKIIDWQDRSTAVLFGDG
                     AGGVLLEASEQQHFLAEALHTDGAQGQSLTSGQSSLRSPFSQGQEVNSFLQMDGRAIF
                     DFAIRDVSRSITAIIEQSGLAKEELDYLLLHQANRRILDKMAKKIGMPREKFLENMMH
                     YGNTSAASIPILLSESVQNGQLKLDGSQHILLSGFGGGLTWGSLIVKI"
     gene            22524..22748
                     /locus_tag="TV191_000350"
     CDS             22524..22748
                     /locus_tag="TV191_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEL1506900.1"
                     /translation="MAVFEKVQEIIVEELGKDAEEVTLETTFDDLDADSLDVFQVISE
                     IEDAFDIQIETEEGLNTVGDLVAYVEEKTK"
     gene            22943..23929
                     /gene="fabK"
                     /locus_tag="TV191_000351"
     CDS             22943..23929
                     /gene="fabK"
                     /locus_tag="TV191_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEL1506901.1"
                     /translation="MKTRITELLNIDYPIFQGGMAWVADGDLAGAVSNAGGLGIIGGG
                     NAPKEVVKANIDRVKAITDKPFGVNIMLLSPFADDIVDLVIEEGVKVVTTGAGNPGKY
                     MERLHEAGIIVIPVVPSVALAKRMEKLGVDAVIAEGMEAGGHIGKLTTMTLVRQVVDA
                     VSIPVIAAGGIADGRGAAAAFMLGAEAVQVGTRFVVAKESNAHQSFKDKILKAKDIDT
                     VISAQVVGHPVRSIKNKLTSAYAKAEKEFLADRKAASDIEEMGAGALRNAVIDGDVIN
                     GSVMAGQIAGLIRAEESCEAILKDIYYGAAAVISQEAKRWQALAADDKNETI"
     gene            23942..24862
                     /gene="fabD"
                     /locus_tag="TV191_000352"
     CDS             23942..24862
                     /gene="fabD"
                     /locus_tag="TV191_000352"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEL1506902.1"
                     /translation="MTKTAFLFAGQGAQTLGMTRDLYDQYAIARDTFDQASQLLGYDL
                     RKLIDTDQDRLNQTAYTQPAILTASVSIYRILTSYGVHPDMVAGLSLGEYSALVAAGV
                     LSFETALELVAKRGRFMEEAAPAGSGKMVAVMNTEARLIEEACQEASSVGVVSPANYN
                     TPGQIVIGGTAEAVNAALEILKAKGVKRLIPLNVSGPFHTALLAPASQRLAEELSKIQ
                     FQDFDLPLVGNTEAKVMEKDRIAELLARQVMEPVRFYDSIEVMKANGITQFVEIGPGR
                     VLTGFIKKIDKKLLCSSVEDMPSLQLYLGK"
     gene            24879..25613
                     /gene="fabG"
                     /locus_tag="TV191_000353"
     CDS             24879..25613
                     /gene="fabG"
                     /locus_tag="TV191_000353"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEL1506903.1"
                     /translation="MEIKGKNVFITGSTRGIGLAMAHQFAGLGANIVLNGRSAISDEL
                     VETFKDYGVKVVPISGDVSEGADAKRMVDEAIEQLGSVDILINNAGITNDKLMLKMSE
                     EDFERVLKINLTGAFNMTQSVLKPMTKARQGAIINVSSVVGLTGNIGQANYAASKAGL
                     IGFTKSVAREVAARGIRVNAIAPGFIESDMTGVLSEKMQEQILNQIPMKRIGKGQEVA
                     QAASFLASQDYITGQVLAIDGGMTMQ"
     gene            25629..26861
                     /gene="fabF"
                     /locus_tag="TV191_000354"
     CDS             25629..26861
                     /gene="fabF"
                     /locus_tag="TV191_000354"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEL1506904.1"
                     /translation="MTLNRVVVTGYGVTSPIGHTPEEFWSSLKAGHIGIKPITKFDTS
                     DFAVKNAAEIQDFPFDKYFVKKDLNRFDMYSLYALYAATEAIEHAGLDIEAIDSDRFG
                     VIVASGIGGIQEIEEQVIRLHEKGPKRVKPMTLPKALPNMAAGNVAMKLNAQGVCKSI
                     NTACASSNDAIGDAFRTIKFGLQDVMMVGGSEAAITKFAIAGFQSLTALSTTEDPSRS
                     SIPFDKDRNGFIMGEGSGMLVLESLEHAQKRGATILAEIVGYGNTCDAYHMTSPHPEG
                     LGARKAINLALQEAGIDAAAIDYVNAHGTSTPANEKGESQAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIATIEAIRHNYVPMTAGTKELSDDIEANVIFGQGKEADIRYAMSN
                     TFGFGGHNAVLAFKRWED"
     gene            26863..27336
                     /locus_tag="TV191_000355"
     CDS             26863..27336
                     /locus_tag="TV191_000355"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEL1506905.1"
                     /translation="MNIQEIKDLMAQFDASSLREFSFKSSDGELLFSKNEHRPMAAPA
                     PEPVTLHQEVAPISLTQEIVSKQESIPASSGLQEPEGEVVDSPLVGVAYLAAGPDKPP
                     FVTVGDSVKKGQTLLIVEAMKVMNEIPAPCDGIVTEILVANEDVVEFGQGLVRIK"
     gene            27333..27755
                     /gene="fabZ"
                     /locus_tag="TV191_000356"
     CDS             27333..27755
                     /gene="fabZ"
                     /locus_tag="TV191_000356"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEL1506906.1"
                     /translation="MMDIKQIQEALPHRYPMLLVDRILEASDDEIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKEENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTARFIKRRGTIAVVEAKAEVDGKLAASGTLTFAFGQ"
     gene            27789..29153
                     /gene="accC"
                     /locus_tag="TV191_000357"
     CDS             27789..29153
                     /gene="accC"
                     /locus_tag="TV191_000357"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEL1506907.1"
                     /translation="MFNKILIANRGEIAVRIIRAARELGISTVAVYSEADREALHTIL
                     ADQAICIGPSRSKESYLNMNSVLSAAVVTGAQAIHPGFGFLSENSKFVTMCEEMNIKF
                     IGPSGAVMDKMGDKINARAEMIKAGVPVIPGSDGEVYNAQEALEIARQIGYPVMLKAA
                     AGGGGKGIRKVESEADLEAAFNAASQEALGAFGNGAMYLEKVIYPARHIEVQILGDSQ
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGTTLRQRMGEAAVRAAKAVSYENAGTIEF
                     LLDEASGDFYFMEMNTRVQVEHPVTEFVTGVDIVKEQLRIAAGLPLSVRQEDIVITGH
                     AIECRINAENPSFNFAPSPGKITDLYLPSGGVGLRIDSAVYSGYTIPPYYDSMIAKII
                     VHGDNRFDALMKMQRALFELEIEGIMTNIDFQMDLISDKQVIAGDYDTSFLMETFLPS
                     YNKD"
     gene            29162..30028
                     /locus_tag="TV191_000358"
     CDS             29162..30028
                     /locus_tag="TV191_000358"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEL1506908.1"
                     /translation="MALFSKKDKYIRITPNNSLKSSVSRNVPEVPDELFAKCPACKHM
                     IYQKDLGPAKICPTCSYNFRISAQERLTLTVDEGSFQELFTDIETKDPLRFPDYQAKL
                     QKARQATGLHEAVLTGTALVKGQRLALAIMDSHFIMASMGTVVGEKITRLFELAISER
                     LPVVIFTASGGARMQEGIMSLMQMAKVSAAIKKHSNAGLFYLTILTDPTTGGVTASFA
                     MEGDMIIAEPQSLVGFAGRRVIETTVRENLPDDFQKAEFLKEHGFVDAIVKRTDLRDR
                     IAHLVAFHGGVS"
     gene            30025..30795
                     /locus_tag="TV191_000359"
     CDS             30025..30795
                     /locus_tag="TV191_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEL1506909.1"
                     /translation="MTDVARILKEARDQGRMTALDYASLIFDEFMELHGDRQFADDGS
                     IVGGIAYLADQPVTVIGIQKGKNLQDNLARNFGQPHPEGYRKALRLMKQAEKFGRPVI
                     TFINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQ
                     VWMLENTMYAVLSPEGFASILWKDGSRATEAAELMKITAAELYQMGVIDRIIPERGYF
                     SSEIVEMIKSHLIDEITQLQAKPLEELLDQRYQRFRKY"
     gene            complement(31027..32304)
                     /gene="serS"
                     /locus_tag="TV191_000360"
     CDS             complement(31027..32304)
                     /gene="serS"
                     /locus_tag="TV191_000360"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEL1506910.1"
                     /translation="MLDLKRIRTDFDTVAAKLKTRGVSEAILTSLKALDEQRRTLLVQ
                     TEELKAQRNIASAAIAQAKRQKEDASQQIADMQQLAANIKAIDAKLADIDQEITGIIT
                     VLPNTPHDSVPIGADEEDNVEIHRWGKPRQFDFDIKAHWDLGEALDILDWERGAKVTG
                     ARFLFYKNLGARLERALYNFMLDEHLKEGYQEIIPPYMVNHDSMFGTGQYPKFKEDTF
                     ELDGTNFVLIPTAEVPLTNYYRGDIIDGKELPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPETSYEELEKMTANAEHILQKLKLPYRVLALCTGDMGFSAAKTY
                     DLEVWIPAQNTYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEVLRPYMGGLEVIKPR"
     gene            32904..33956
                     /locus_tag="TV191_000361"
     CDS             32904..33956
                     /locus_tag="TV191_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HEL1506911.1"
                     /translation="MTLDKNRHYGLDLLRIISMFMIVITHVLGKGGLRSTVEGEADSY
                     FIVTWMIQVLVYGAVNCYALISGYVGIKSPYKYSKIVNIWVQVFFYSFLMTLLFALFG
                     FPVSLENWRQALFPIVSGNYWYITAYFGLLIFMPMINGGLNTLSNKQLGRLVLLVFAI
                     FSLIPALMNQQVDEFSLSKGFEMTWLIILYIIGAYLRRIELSRFSHKLLIAVYMGSLV
                     VTYIMKFMVGNIWYWYVSPSLTLGAIALFILFAKLKLTSETLLLRFIVIVSPTTLGIY
                     LVHLHPLLVKFIIRDFAEPFVNAPILLYPLLIFGVGIVIYFLSFLVEQARLMLFKKLG
                     FQNLLKWVDKKIPFAD"
     gene            complement(34277..34660)
                     /locus_tag="TV191_000362"
     CDS             complement(34277..34660)
                     /locus_tag="TV191_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEL1506912.1"
                     /translation="MAQSLNQRVILQTTAVSYLGIGGKVGKILLGDKALEFYNDKNVE
                     DFIQIPWTAINQIGANVSGKKVSRHFEIFTDQGKFLFASKDSGKILKVARETIGNDKV
                     IKLPTLVQTIIAKLFHHQKKDKKSH"
     gene            complement(34794..35705)
                     /locus_tag="TV191_000363"
     CDS             complement(34794..35705)
                     /locus_tag="TV191_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEL1506913.1"
                     /translation="MTEQIKLTKADRKRVWWRSQFLQGSWNYERMQNMGWAYALIPAL
                     KKLYTTKEDRAAALERHMEFFNTHPYVAAPIIGVTLALEEERANGTAIDNAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGALGASLAQTGNLVGPLLFFFGWNIIRMAFLWYTQE
                     FGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVSINFTINLPGKQLSEGA
                     YVVFPEGAVKGAELKSILGQAMGGMSLDKVQSQTLQGQLDSLIPGLAGLLLTFLCMWL
                     LKKKVSPIAIIIALFAFGIIAHLLHIM"
     gene            complement(35721..36530)
                     /locus_tag="TV191_000364"
     CDS             complement(35721..36530)
                     /locus_tag="TV191_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEL1506914.1"
                     /translation="MSDISLISAILVVIVAFFAGLEGILDQFQMHQPLVACTLIGLVT
                     GHLEAGVMLGGTLQMLALGWANIGAAVAPDAALASVAAAIIMVKGGDFTQKGITFAYS
                     TAIPLAVAGLFLTMIVRTISTVLVHAGDKAALEGNFSAIERFHFAALLLQGLRIAVPA
                     ALLVAVPTEAVQSVLKAMPAWLNEGMQIGGAMVVAVGYALVINMMATREVWPFFALGF
                     ALAAVTQLTLIAMGVIGVAIAFIYLNLSKQGGNGGGRAGSADPIGDILEDY"
     gene            complement(36701..37693)
                     /gene="manX"
                     /locus_tag="TV191_000365"
     CDS             complement(36701..37693)
                     /gene="manX"
                     /locus_tag="TV191_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEL1506915.1"
                     /translation="MGIGIIIASHGKFAEGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYGHFNNAIAQFDADDEILVLADLWSGSPFNQASRVAGENPDRKMAIITGLNLPMLIQ
                     AYTERLMDANAGVEQVAANIIKESKDGIKALPEELNPVEEASTANGGGQALQGAIPKG
                     TVIGDGKLKINLARIDTRLLHGQVATAWTPASKADRIIVASDSVAKDELRKQLIKQAA
                     PGGVKANVVPINKLIEASKDPRFGNTHALILFETVQDALRAIEGGVEIKELNVGSIAH
                     STGKTMVNNVLSMDKDDVAAFEKLRDLGVSFDVRKVPNDSKKNLFELIQKANVQ"
BASE COUNT        10623 a         7417 c         9143 g        10699 t
ORIGIN      
        1 tcctgctcca acttgtcata aatgtagcta tcaaaggttg caacgctttg cagcgcacgt
       61 gtatcaacaa catgggtcaa aatcaaggca gcaccattac gcaaagcgac attaaccccc
      121 ttgtgaaagg ctaattcgga gccatgagag ccatcaatag cgaccatgat acgttcatat
      181 gtttgtgaca tcggtttatc ctcctttgaa ctttatctct atagctatta tacctttttt
      241 gaggagaaat tgaaaacgtt ttaatgattt tctgagctat tgttcaccaa atagcccagc
      301 tattccctga ggtgaggata ccttgagcta gaagctagct tagatagcct tattaatagc
      361 tgctgcttag cttgcttaga gctttggttg agcttttggc attctttaag ctcatagaaa
      421 agtgctttct attttaattg ttttggttta taatatgggt tacgaggtaa tgagactatg
      481 aaaataattg aaaaatcatc aaaattagaa cacgtagcct acgatattcg aggtccagtc
      541 ctggacgagg ctaatcgtat gatagctaat ggtgaaaaga tccttcgatt aaatacaggt
      601 aacccagcag cctttggctt tgaggctcca gatgaggtta ttcgtgattt gattctcaat
      661 gctcgctcca gcgagggcta ttctgatagc aaggggattt tttcagctcg taaggccatc
      721 atgcaatatt gtcagctaaa gggctttcct gatgttgaca ttgatgatat ttatttggga
      781 aatggtgtct cagagctgat ttcgatgtct cttcaagcct tgctcgataa tggtgatgag
      841 gtgctggtgc caatgcctga ctatcccctt tggacagcct gtgtcagcct aggtggtggg
      901 catgcggtgc attacctgtg tgatgaagag gctgaatggt atcctgatat tgctgacata
      961 aaagccaaga tcactgagcg cacaaaagct atcgtcatta tcaatcccaa taacccaaca
     1021 ggtgctctct accctcgaga ggtcttagag gagattgttg caattgccag agagcatcag
     1081 cttatcattt ttgcagatga gatttatgat cgtttggtca tggacggtgg ggagcatatc
     1141 gcaattgcca gccttgcacc tgatgttttt tgcgtgtcaa tgaatgggct gtcaaaatca
     1201 caccgtattg ccggctttcg agtgggctgg atggtcttgt caggccctaa aagacatgtc
     1261 agaggttaca ttgaaggctt gaacatgctg gcaaacatgc gcttgtgctc caatgtctta
     1321 gcgcagcagg tggtgcagac ctccttagga ggacgtcagt ctgttgatga gctcttgctt
     1381 ccgggtggtc gcatctttga gcaacgtaac ttcatttacc aggccattaa tgccattcca
     1441 ggcctatcag ctgtaaagcc taaggcaggc ctctatttgt ttccgaaaat tgatcgaaat
     1501 atgtaccgca ttgatgacga cgaggaattt gtcctacagc ttttgaagca agaaaaggtc
     1561 atgctggtac atgggcgtgg cttcaactgg aaggagcctg atcattttcg cgtggtctat
     1621 ctgccaacag tagaagagct agctgacgtg caagaaaaga tcacgcatgt tctcaagcaa
     1681 tacaagcgct aatatgattc tcatacaaaa attggatcgc gagatccttt ttgtttttca
     1741 gcaaaataag gctctggcct catccgaatt gtaggtataa tagccaattt tctgataatt
     1801 ccttgcaaaa gctagggtcc tttgatataa ttgtaacgca aataattaaa aggaaaagaa
     1861 aaaatgccaa atttattaga aaaaacccgt aagattactt ctattttgca acgttctgta
     1921 gacagcttgg aaacagaact cccctataac actatggctt cacgcttagc agatattatt
     1981 gattgtaatg cttgtatcat caatggtggc ggcagcttac ttggctatgc gatgaagtac
     2041 aagaccaaca cagaccgcgt cgaggaattt tttgaaacaa gacagttccc agatgcttat
     2101 gtcaaggcag ctagtcgtgt ttatgacact gaagcaaacc tttctgtgga aaatgaacta
     2161 acgatttttc ctattgagtc aaaggatatc tatcctgatg gtttaaccac gattgcccct
     2221 atctatggtg gcggcatgcg cttaggtacc ttgatcatct ggcgtaacga caatgaattc
     2281 agtgatgatg accttgtttt agttgaaatc tcaagcactg tggtcggtat tcagctgtta
     2341 aatcttcaaa cagaaaacct agaagaaacc attcgtaagc agacagttgt taatatggca
     2401 atcaacactc tatcttactc tgaaatgaag gctgttgcag ctatccttag tgagctagat
     2461 ggcaatgaag gacgcctgac cgcttcagtg attgcagatc gtattggaat cacacgatct
     2521 gtcatcgtga atgcccttag aaagctagag agtgcaggta tcattgagag tcgctctcta
     2581 ggaatgaaag gcacttatct caaggtgatt aacgaaggca tctttgacaa gctaaaggaa
     2641 ttttaatagc tcagatgcga tcgtctgcta agcccaaggc ttgcctttag ctttgctagc
     2701 tgtgattagt cagagcaggt agtgaaagtg ttagctatga tcaaagtctt gctgcttata
     2761 gagcagccat tcattagcca gagccctgct tggtaagggc tagacttggt ctttatgacg
     2821 gcttatcgga gtttcttagc agctgtggag gacttcacac attattatag cgtcccctca
     2881 aaggttctag cattggctgg cttttgaggg gtattttttg tattttcgct gtgattcagc
     2941 atgagatgaa catgacagat gcatgaaaga tttttagcaa gaaaataagg ctttctgtat
     3001 ttcaatgttc agctatttca ggaatatatc ttattttcat atagaaaaac gttgaaagtg
     3061 tctacttaaa tctatactat agttcagaaa taactgtttt tcgcctttat cgtgtataaa
     3121 tcaatccgct gtcttgacag ctgtcgtgtt tagtggtaaa ctataagtgt ctaatcatac
     3181 tgaatattaa aagcaggctt agttcttatg gcttgctgtc atgcagctaa gagagcataa
     3241 gctttttggg gagggataag ctgtgaaggc cttgatttct attgattaca cgaatgactt
     3301 tgtagctgat gatggtagcc tgacggcagg agcacctgct caggtgattt cagaggcgat
     3361 ggctagcgtt gttgaggctg cctttgaggc cggctactat atcttttttg cgattgatgc
     3421 ccacgaggag ggagatagct ttcatccgga ggcagccttg tttccgccgc ataatattat
     3481 cgggacaagg ggtcgggacc tgtatggtcc tttgatgacc gtatatacca gataccagca
     3541 agatcagcgg gtcttttggc tggataagcg gcattattct gccttttcgg ggactgattt
     3601 ggatattcgt cttcgtgagc gtggcgtcac gacgctggtc ttgacaggtg tgctgacgga
     3661 tatttgtgtc cttcatacag cgattgatgc ctataaattg ggctacaagc ttgagattat
     3721 cacatcagca gtggcgagca attcaacaga aaatcaccag tgggcgctga accactgtag
     3781 gactgtccta ggagcaaagc ttcttgatcg gctttcttag gcgatcgttc gatcagctgg
     3841 gataggctaa tcaagtaagg cagtattagc tgctgcttgg ctcagcgctg atcttaaggg
     3901 cttcttagtg agatcttttg gtcttggcta ggaggctttt tgttattaag tttttcgcta
     3961 atcccagcta cgcatacacg tgaataaaat gcaggtagct atgctctagc cacattgccc
     4021 ttttaacctc atcaattgct caaatgcagt ttagttatag cctggctgtt cttgaaaaaa
     4081 gcaggttgag cttatgaaaa acgttatcag aaaacgtcag ttgccacatg catttgacgt
     4141 gaaatcccag cagtccgcta tggtaaataa agctaattat gatataatgg ttaagactat
     4201 gtaaaattgg gttattcagg ctattatcaa gcgtttgaaa cagcaaggcc ttgtggctga
     4261 tgatggtctg ctttaccttg gataggagaa ttcatgaaaa tttctgaaga agaggttcgc
     4321 cacgttgcgg ccctatcaaa gctatccttt tcagaaagtg aaacaactga gtttgcgaca
     4381 acattatcaa aaatcgttga catggttgaa ttgctaaatg aagtggatac gacaggtgtt
     4441 gccattacca ccacaatggc agacaagaaa aatatcatgc gagctgatat cgctgaggct
     4501 ggagtggatc gcaagctcct gtttcaaaat gttcctgaaa aagaaaatca tttcatcaag
     4561 gtaccagcta ttcttgatga cggaggagat gcctaatgtc ttttaatcat catactatag
     4621 aagaattaca tgagcttctt gttgcaaagg acatttctgc agttgagcta acaaaggcaa
     4681 cccttgagga tatcaaggcg cgtgaggagg ctgtgggttc tttcattacc attgcttgcg
     4741 aggctgcttt aaagcaggct gctgcacttg atgctaaggg gattgatcct gacaatgtga
     4801 tgtcaggaat accactagct gtcaaggaca atatctcaac caaggggatt ctgacaactg
     4861 ctgcttctaa gatgctttat aattatgagc cgatttttga tgcgacagcg gtagctaatg
     4921 cctacgacaa ggatatgatt gttattggta agaccaatat ggacgagttt gctatgggtg
     4981 gctcaacaga aacgtcttat ttcaagaaaa ccaaaaacgc ttgggatcat agcagggttc
     5041 ctggtggttc atcaggtggc tctgcaacag cagtagcttc aggtcaggtt cgcttatctc
     5101 ttggctcaga cactggcggc tctattcgtc agccagcagc ctttaatggt gttgttgggc
     5161 ttaagccgac ctatggggct gtttctcgct atggcttgat tgcctttggc agctcgctag
     5221 atcagatagg gccttttgcg ccaacggtaa gagaaaatgc ccagctgcta tcggtcattg
     5281 cagggagtga ccgcaaggac tcaacctcag cacctgtaca gatcgctgac tacacaatta
     5341 agatcggtca agacatcaag ggcatgaaga ttgcactacc taaggaatac cttggcgaag
     5401 gcattgatcc taagattaag gagacggttt tggctgctgc taagcatttt gagaagctag
     5461 gagctatcat tgaggaggtc agtctgccac atagcaagta tggggtggct gtctattata
     5521 tcatcgcttc atctgaggcc tcatcaaacc tacagcgctt tgatggtatt cgctatggct
     5581 ttcgtgctgc tgatgccaag agccttgagg acatctatgt caagacgcgt agtcagggct
     5641 ttggtgatga ggttaagcgt cgtatcatgc ttggtacctt tagcttatca tcaggctatt
     5701 acgatgctta tttcaaaaag gcaggtcagg ttcggacgct gatcattcaa gactttgaga
     5761 aggtttttgc tgattatgac ttgattttag gaccaacagc accaacagca gcctttgagc
     5821 ttgatacgtt gaatcatgat cctgttgcca tgtatttggc tgatcttttg accattccgg
     5881 tgaatctagc gggcttgcct gcaatctcta ttccagcagg ctttgcagat ggcttgcctg
     5941 ttgggcttca attgatcggt ccaaaatata gcgaagaggt catctatcag gtagcggtag
     6001 cctttgaagc gactactgac taccacaagc agcagcctat gatttttgga ggtgacaggt
     6061 aatgaatttt gaaaccatta ttggacttga ggtccatgtg gagttgaata ccaattctaa
     6121 gattttctca ccttcatcag ctcattttgg agaggatcca aatgccagca ctaatgtgat
     6181 tgactggtct ttcccaggtg tccttccagt gatgaacaag ggagtcattg atgcgggaat
     6241 caaagcagca cttgctctta acatgtctat tcatcagcac atgcactttg accgtaagaa
     6301 ttatttctac ccagacaatc ccaaggccta tcagatttca cagtttgatg agccgattgg
     6361 ctacaatggc tggattgata ttactcttga ggacggctca accaagaaaa tccgtattga
     6421 gcgtgctcac ctagaagagg atgccggcaa aaatacgcat ggtacagatg gttattccta
     6481 tgttgacctc aatcgtcagg gagtgccctt gattgagatc gtctcagagg ctgacatgcg
     6541 ctctccagag gaggcctatg cttacctgac tgccctaaag gaaatcattc agtatactgg
     6601 tatttctgat gtcaagatgg aagaggggtc catgcgtgtg gacgccaata tctccttgcg
     6661 accatacgga caagaggcct ttggtacaaa aacagaattg aaaaacctga actcatttag
     6721 caatgtgcgt aaggggcttg agtttgaggt ggagcgtcaa gccaaaatcc tacgctctgg
     6781 cggtgttatt cgtcaggaga cacgtcgtta tgacgaggca agtaagggaa cgattctcat
     6841 gcgtgtcaag gagggagcag cagactaccg ctatttccca gagccagatt tgccattgtt
     6901 tgagattgat gacgcatgga ttgaggatat gcgtgcagag cttccaagat ttccggcaga
     6961 caggcgagct agctacatta atgctcttgg cttgtcagcc tatgatgcag gtcagctgac
     7021 agcaacaaag gctttgtctg atttctttga gcaggctgtg gcacttggtg gtgatcctaa
     7081 gcaggtgtct aattggcttc agggtgagat ggctcaattc ttaaatgctg agggcaagac
     7141 gattgatcag attgccttga ccccagaaaa tctcgtggaa atgattgcga tcatcactga
     7201 tggcacgatt tcatcaaaaa tcgccaagaa ggtttttgtt catttggcaa agcatggcgg
     7261 ctcagcgcgt gcttatgtgg aaaaggccgg cttggttcaa atttcagacc cagctgtctt
     7321 gattccaatc attcatcagg tgtttgctga caatgaggct gctgtggcag atttcaaatc
     7381 aggcaagcgc aatgctgaca aggcctttac tggttttctg atgaaggcca caaaggggca
     7441 agccaaccca cagatagctc agcaattgtt agcccaagaa ttgcaaaaat tgctggatta
     7501 aggagtcgtt atgactggca ttgagtctga aacagagttt tcaggctctt tatgatggta
     7561 ggctctttag gacaattctg tgataatacc tcgctatccg aagctgtaag aggtagctta
     7621 tcggtctgtt gttaatgact gttaagcagg cttggtgaag tctaggctag agctatcaag
     7681 gtattatgag tggccttatc atggcatgga ttaaaaagag gaagataata tgtcaagaaa
     7741 tggaaaaggc agtaccatga ttttactagc cggaatcgcc tggggtctct caggggtgtc
     7801 agggcaatat ttaattgctc atggggtcgg catcaatgcc ttgacctcac taaggctcat
     7861 tatttcaggg cttgtgctgt cagctatggc ttatgtgcgg caaagagagg ctgtcatcag
     7921 cttactcaag gacaaaaggc ttttaagaga gctgttgatt tacagtctat ttggtctcac
     7981 acttaatcaa tatgcctatc tgcttgctat tcgttactct aatgctggta cagccacagt
     8041 cctgcaatac ctttccccca ttttggtgct ggtctaccta tcgttcaaat caagacgcct
     8101 gccggctgtg ggagagagct gtgctatttg cctagcgatc ctaggaacgg ttatcatggc
     8161 ctgtcatggt gatctttccc atctggcaat caatcctatt ggacttttct gggggctttt
     8221 tgcagcggtg acctatgctt actgtgtcat caagcctgct aagctgattg ccgactgggg
     8281 gagcttgctg attgttggtc ttgccatgct gatgggagga gtgatttttc cgatcctgac
     8341 aagagcatgg cagtacccat tggcaatgac ttatgggaat ctacgggccc tgtttggcat
     8401 tatcggtatt gggacaattt ttgcctacac cttttttcta aagggggctt caatcattgg
     8461 accgatcaag gctaccttgc tggcttcaat tgagccggtt gcctctgtct gctttgcgat
     8521 tatcctgatg aaagagattt ttcaccctat tgatctgtta ggaatggcct tgattttaat
     8581 agcagtgctt gtgatatcgc tgagagactt attgcttact aagagaaaaa agcagcttgc
     8641 tcttaatatc aagcgaccac catcatctga ctgatataag gcaagggtat ggtataataa
     8701 gacaaaacat aaaggagatt tgcgatggtt tggtcattaa ttgttggagc tattatcggc
     8761 atggttgcag gtaggataac agaaaaaagc cattcgatgg gctgtttcac aatgactgct
     8821 gctggtttga taggctctgc agttggtcaa aagctgtttg gcgactgggg tattcagctg
     8881 gcaggcatgg ctgttttccc ttcaattcta ggagcagcta ttgtgataat tgttgcttca
     8941 gcgctctttg gcaaaaaaca ataagccagg agtacttgtg acgttcaaat atataaaaat
     9001 ccttgtatca gtatgatacg aggatttttt ggttatcaga tttgtaaaaa caatcgaata
     9061 tatcagatga taaaaattta aaagaaatat gataaagtct tgactatata tactatttct
     9121 tggtattttt accaaaaaat atggagagag ttaaaaaagt atgagaaaaa cagaaggacg
     9181 ttttcgcaca tggaagtcca aaaaacaatg gctatttgcc ggtgcagtgg tgaccagctt
     9241 gctgctggga gctgcacttg tctttggagg tttattagga agtcttggtg gctcatccca
     9301 tcaagcgagg ccaaaggagc agccagtcag ctcgattgga gatgacgata agtcgcacaa
     9361 gagctcatca gattcaatgg tcagtcggcc accgaaaaag gataacttgc agcctaagcc
     9421 ttcagatcag cctactaatc atcagcatca ggctactagc ccgtcccagc cgacagcaaa
     9481 gagctcaggt catcatggga atcaacctca gtctctcagt gtgaacagcc aaggaaatag
     9541 tagtggacag gcctcagagc ctcaggctat tcctaatcaa gggccttccc agccactggg
     9601 gctgagagga ggtaacagct ctggttcagg tcatcaccat cagccacaag gaaagccaca
     9661 gcacttagat ctaggtaagg ataattctag cccgcagcct caaccaaagc ctcagggcaa
     9721 tagtcccaag ctgccagaaa aaggcttgaa tggtgaaaat cagaaggaac cggagcaagg
     9781 tgaacgaggt gaggctggtc ccccactttc agggttgagt ggtaataatc aaggccgtcc
     9841 ttcgcttcca ggcttgaatg gtgagaatca gaaggaacca gagcaaggtg aacgaggtga
     9901 agccggtccc ccatcaactc cgaatttaga aggaaataat cgtaaaaatc ctttaaaagg
     9961 attagatgga gagaataagc caaaggaaga tttagacggt aaaggcttaa gcggagaaaa
    10021 tgatgaatca ccaaaactta aagacgaaca cccctacaat catggtcgtc gtgatggtta
    10081 ccgagttggc tatgaggatg gatatggtgg caaaaagcac aaaggagatt atcctaagcg
    10141 gtttgatgag tctagtccaa aggaatataa tgactatagt caagggtata atgataatta
    10201 tggaaatggc tatttagatg gtctagctga tagaggtggt aagagaggat acggctattc
    10261 ttacaatccc gactaatctt ctgctatccc ttaattaacc tacaaaaaag ctgggcttcc
    10321 ttagacccag cttttttggc agcttcaaac gtcttatctt ttattagctg ctattatatt
    10381 ataaagtcta aatattaata aacggtatca attggataac aaactctttt ttctggtacc
    10441 cattgttcta tttttgcaag gggctaccag acctcttgtc tctgatagct ttctcttttt
    10501 gtttgtgata aaatataaca catattgagg aggtgtgcca tgaaagctat cattacagtt
    10561 gttggtaagg acaatcaagg gattgtcgca ggtgtttcag gacaaattgc tgcattaggg
    10621 ttaaatattg atgacatttc acagaccgtt ttagatgatt attttaccat gatggccatt
    10681 gtctcaagca gtgaaaagca ggattttgct catctgcgtg aggtgcttca ggcttatgga
    10741 aagcaattgc aggtgacgat taatattcaa agcgcagcga tttttgatgc tatgcataac
    10801 atataaggag cttgatgact atggatatta gacaggttcg tgaaacagtt gagatgattg
    10861 aggagcagca ttttgatatt cgtaccatta cgatgggaat ttccttgctg gattgtattg
    10921 attcggatat tgatagagct gccgctaaga tttaccaaaa gattacgaca aaggcagcta
    10981 atcttgtggc ggttggtgat gacattgcag cagaactagg tattcccatt gttaataagc
    11041 gcgtctctgt aactccgata gcccttattg gggcggcaac agacgcagaa gactacctgt
    11101 cgcttgcaaa agctctggat caggctgcct gtgatatcgg agttgacttt atcggtggct
    11161 tttcagctct tgtgcaaaaa ggctatcaaa agggtgataa gattttgatt gagtctattc
    11221 ctcaggcttt ggctcaaaca cagaaggtct gcgcttcggt caatgttgga tcaacaaggt
    11281 ctggtattaa tatgacagca gttgcagaca tggggcgtat catcaaggaa accgccaaag
    11341 cctctgagat aggggcagca aagctagtag tctttgctaa tgctgttgag gacaatcctt
    11401 ttatggcagg agcctttcat ggtgtcggtg aggcggatac ggtgattaac gttggtgttt
    11461 caggacctgg tgtggtcaaa agagccttgg aaaaggttcg tggtgaaagc tttgacgttc
    11521 tagccgagac cgtcaaaaaa acggccttta aaatcacgcg tatcggtcag ctagtgggac
    11581 agatggcaag tgagcggcta ggtgtgggct ttggtgttgt ggatctgtcg ctagctccca
    11641 ctccagcagt tggtgactct gtggcacgtg tcttagagga gatgggactt gaaatagttg
    11701 gcacacatgg cacgacagct gccctagctt tacttaatga cgcagtcaaa aagggtggtg
    11761 tcatggcttg caaccgagtg ggtgggttgt caggtgcctt tatccctgta tcagaggacg
    11821 agggcatgat tgcagcagtg cagggaggct cgcttaatct tgaaaagcta gaagccatga
    11881 ctgccatttg ctcggttggt ttggatatga ttgcgatccc agaggagaca ccgtctgaaa
    11941 ccattgcagc catgattgct gatgaggcag ctatcggggt gattaatcaa aagacaacag
    12001 ctgttcgtat tattccaaag ggtaaggagg gtgatatgat tgcttttggt ggtcttttag
    12061 ggacagctcc ggttatggct gttaatccgc attcatcggc tgactttatt gctcgtggtg
    12121 ggcagatacc agctcctatc catagcttta agaattaacg gctagcactt gcatggtttt
    12181 gcaagtgttt tcttttaatg ctataatagc agagagactt tggaggttca ttatgacaaa
    12241 aacaagatta tacattgtca gacatggcaa gacgatgttc aacaccattg gtcgtgcaca
    12301 gggttggagt gataccccct tgacaaaggc aggagaagaa gggattcgtg aattgggact
    12361 tggtttgaag gctgctggta ttccattcaa ggctgctttt tcgagtgatt caggtcgtac
    12421 catgcagaca atggagatta ttctacgaaa gtctgaaaat gagtttttac cctacactag
    12481 agataagcgg attcgtgagt ggtgctttgg tagtctagat ggggcttatg attccgagct
    12541 gtttttaggt gttttaccta gaacaaaggc ctttgaaaat cgtgacaatc tgcgtgatgt
    12601 gccttattca gaattagcag agagtattgt cgaggttgat actgctaact gggcagagcc
    12661 ctgggaggta ttgagcaagc gtatctatga gggctttgag gctatcgcgc ttgctgttga
    12721 aaatgcagga ggtggcaatg ctatcgtggt tagtcatggc atgaccattg gaacctttat
    12781 gtggctaatt gacccagata gggaaaagca atacattgac aatggaagcg tcactgttgt
    12841 ggaatatgag aatgggcagt ttaccatcaa aacgattgga gatatgagct accgctatcg
    12901 tggtcgtgag ataattgagt caataagaga tgaagaataa cactataaga gtccttttac
    12961 aggccttggt cgtcctgttg tttttatcag gggtttacct ctttatcaag cctgaaaaac
    13021 aggctgtagg ccccaaggct aatcaaacag tacctgcccc aaaggcagct aagcaggcta
    13081 aaaagactac tgatctgcca aaggtatcaa ctacggactg gcagctggtc cttgtcaatc
    13141 gcgatcaccc tcaagaggaa atgagtcctg agttggttga gattaatggg attcctattg
    13201 ataagcgcat tgagcaggag acggctgatt ttctagcagc ggcgcagacg attgaacctc
    13261 aggagcactt gattgctggt tatcgttcgg ttgtccagca agaagagctt tatcagtctt
    13321 atattgccca agagctggca aatgatccta gcctgaccca agaggcagct gaagccttgg
    13381 ttcggaaata tgcccagcca gcaggcacta gtgaacatca gactggtcta gccattgata
    13441 tgagcacagt agataactta aacgctagtg atcctaaggt ggcacaggag attcaaaaaa
    13501 tagctccaca atttggtttt attttgcgct atccaaaagg gaagcagact agcacaggga
    13561 ttgagtatga ggactggcat tatcgctatg ttggtaaagc ctctgcccta tacattaccg
    13621 ctcatagcct cagcctagaa gaatacctaa cacgattgaa ggagaaaaaa tgagaaaacg
    13681 acttaaattt tcctattttc tagtgttttt agtgttcatt atggtggctt tgattggtcc
    13741 cttgctgttc aatgccaaag gcacatcggc cagtcaggag atgtctgttc cctatacaga
    13801 gaggcaattt atccagttgg ttgctaagga ggtcaagcca ttggccaaaa actatggcat
    13861 tcgtccttct attttgattg gtcagattat tttagaaacc aattatggca gaaccctgtt
    13921 ggcggccaaa taccacaacc ttttttcact gcagccagct ccagggcagg cttccattag
    13981 cctcaagaag caagcagcct caaagcacaa gacagcctat gctatctatc gggacagaga
    14041 ggactctatc agagcttact tatcatggct tagtcaaggc acaggcgagg agaaaaagct
    14101 ttaccaaagc ctagcaaccg aaaaagggta taaaaaacct gctaaaagtc tgcagaccta
    14161 tcgctattct gatgataagg gctatgccca aaggcttgtg cagctgattg aagcaagagg
    14221 tttgacaagc tatgatgatt gaggagatga aaaagacacc gaaacaaccg gtaagctcag
    14281 gtatttgctt tagtaggtat tgcaactttc tatcagcttg aaggtgtaag ccttaagagt
    14341 aggagctgtg agcacgcagc ctgatttatc ctgctctact aaaggcttga ttgttaggcc
    14401 ttaaggcttc aggcagttaa gctaatcccc cttacagctt agcgctcctt ttagctagcg
    14461 agtcgggaga agccaatacc agtctgagag gtagtaagtg gctctctatt acttctttca
    14521 agcataatgt caaaggcaac actgtcaatg ttttataaaa attagcactc taaaaaaaga
    14581 gtgctaattt tttgagtttt tttcttgaca tgctagttta aaaggatata atagaattat
    14641 aaattagcag tccgatgtat agagtgctaa cagaaaggga gtgattggtt tgtgatcaca
    14701 gagagacaat ctaatatttt gaatcttatt gtagatttat ttacacagac ccatgaacca
    14761 gttggctcta aggctttgca gtcacttatt gcttctagta gtgccactat tagaaatgac
    14821 atggcaaagc ttgaaaaact aggattgctg gagaaggctc acacatcaag tgggcgcatg
    14881 ccaagtgcgg caggctttaa atattttgta gagcattctc ttaatcttgg cagcattgat
    14941 gagcaggacc tttatcagct ggtcaaggcc tttgattttg aggcctttaa gctggaggac
    15001 gttttgctaa gagccagcca gatgctatcg gatacgaccg gctatacggc ggcgatttta
    15061 gatgttgagc ctgcaaggca aaggctgaca ggctttgata ttgttcagct atctagtcat
    15121 gatgccttgg cagttttgag cttagatgag tccaagccgt tgaccgtaca gtttgccatt
    15181 cctaagaatt ttatgaatcg tgatttgctg gtgcttaagg gcattgttgc tgatcgctta
    15241 cttggcaaag atgttatgac tgttcattac aagctgcgaa ccgaaatccc tcagattgtt
    15301 cagaagtatt ttacggtgac agacaatgtt ttggatttgt ttgattatat ctttgtcggg
    15361 ctttttcgag aaacgatttt tgtctctggc aaggttgctg cccttgacta tgctggtctt
    15421 gcgacctatc agtttcttga tgaggagcag cgcttagccc tatctatcag acagagtcta
    15481 tcagaggaag agatggcaac ggttcaggtt gctgacagca gtgagccagc cctagcaaac
    15541 gtgaccttgc tgacctacaa gtttttaatt ccatacagag gatttggcct cttaagctta
    15601 attgggccag ttgatatgga ttatcgtcgt agtgttagct tgattaatgt gattggtcag
    15661 ctactggctg tgaagctaag agattattac cgttacttaa acagcaacca ttatgaggtt
    15721 cactaaggcc ttaatatgat ttaagaaaat gtaagaaagg ggtagacacc ttgtctaaaa
    15781 aaccaaaaga agagctcaag gatcaagagg acattcttga tgaggctgct gaggaagcag
    15841 tagagccagt tgaagaagct gatcaatcag ctgagcttat tgctgatgaa gcagccgagg
    15901 aaccatctga gctagagttg gctctccagc gagcagaaga ttttgaaaat aaatacctca
    15961 gagctcacgc agaaatgcaa aatattcagc gtcgtgcgaa tgaagaacgc caaagcttgc
    16021 agcgctatcg ttcacaggat ttagctaaaa aaatccttcc aagcttagat aacttggagc
    16081 gtgctttggc tgttgagggt ctgacagatg atgtcaaaaa aggcctagaa atggtgcaag
    16141 aaagccttgt tcaagccctt aaagaagaag gtattgaaga ggttcctgtg gaagcctttg
    16201 accacaatct gcacatggca gtccaaaccc taccagcaga tgatgaccac ccagcagata
    16261 gtatcgctca ggttttccaa aaaggctata agcttcatga gcgcttacta agaccagcga
    16321 tggtggttgt gtacaactag tcactaatga tggccattga aatggctcgt cattagacgg
    16381 caaccgctgt ggcggcttgc ctagactcct tactagctcg atagcaaaat ggtatcgatt
    16441 ttgctatctc acgtcgcaat tatcccgtga tgatagctaa tcaataaaat gaatcatgtc
    16501 cgaaatgacg gtaaactatg aaaataagaa ataagattgc tgctttttgc gctagcaaaa
    16561 gcgaacgaag tgagcattac cgatactctt cgccgtggca aaagtcataa aacactagtg
    16621 ttttatgact cggaaaattt gagactttag gctcaaattt cagctatgag attccatagg
    16681 aagctgctag cgtccgtgcc acataagagg agtatcataa atatataaaa gaggaaaaaa
    16741 tattatgtct aaaattatcg gtattgactt aggaacaaca aactcagcag tagcagttct
    16801 tgaaggaaca gaaagcaaaa tcattgccaa cccagaaggc aaccgcacaa ccccttcagt
    16861 agtgtcattt aaaaacggtg aaatcattgt cggtgacgct gccaagcgtc aagcagtgac
    16921 aaaccctgac actgttatct caatcaaatc aaagatggga acctctgaaa aggttgctgc
    16981 taatggtaaa gaatacacac cacaagaaat ctcagcaatg attcttcaat accttaaagg
    17041 ctatgcagag gactaccttg gtgaaaaggt aacaaaggct gttatcacag ttcctgccta
    17101 cttcaacgat gcacaacgtc aagctactaa ggacgcaggt aagattgctg ggcttgaggt
    17161 agaacgtatc gtcaacgaac caactgcagc agctcttgct tacggtcttg acaagacaga
    17221 taaagaagaa aagatcttag tctttgacct tggtggtggt acctttgacg tgtctatcct
    17281 tgaattgggt gatggtgtct ttgatgtgct tgcaactgct ggtgacaaca agctcggtgg
    17341 tgacgacttt gaccaaaaaa tcattgattt cttagtagca gaattcaaga aagaaaacgg
    17401 tattgaccta tcacaagata aaatggctct tcaacgcttg aaggacgctg ctgaaaaagc
    17461 taaaaaagac ctttcaggtg tcactcaaac tcaaatttca ttgccattca tcactgctgg
    17521 cgctgctggt ccgcttcact tagagatgag cctgtctcgt gcaaaatttg atgacctgac
    17581 tcgtgattta gtagagcgta cgaaggttcc tgttcgccaa gcgctgtctg atgcaggctt
    17641 gagcttgtca gaaatcgatg aggttatcct tgttggtggt tcaactcgta tcccagctgt
    17701 ggttgaagct gttaaggctg aaactggcaa agagccaaac aaatcagtga accctgatga
    17761 agttgtagcg atgggtgctg ctatccaagg tggtgtgatc actggtgatg ttaaagacgt
    17821 tgttcttctt gacgtgacac cattgtcact tggtatcgaa acaatgggtg gcgtctttac
    17881 aaagcttatt gaccgcaaca caacaattcc aacctctaaa tcacaggtct tctcaactgc
    17941 agcagacaac cagccagctg ttgatatcca cgtgcttcag ggtgaacgcc caatggcagc
    18001 agataacaaa acacttggac gcttccaatt gacagacatt cctgcagccc ctcgtggtat
    18061 cccacaaatc gaagtaacct ttgacatcga caaaaacggt attgtttctg ttaaggcaaa
    18121 agacctaggt actcaaaaag aacaacatat tgtcatcaaa tctaacgatg gtctttctga
    18181 agaagaaatt gaacgcatga tgaaagacgc tgaagccaat gctgaagccg atgcaaaacg
    18241 taaggaagag gttgacctta aaaatgaagt tgaccaggct atctttgcaa ctgaaaagac
    18301 tattaaagaa actgaaggca aaggctttga cacagagcgt gatgctgctc aaacagctct
    18361 tgatgagctt aagaaggctc aagagtcagg cgaccttgat gatatgaaag ctaagcttga
    18421 agcgcttaat gaaaaagcac aagcccttgc tgttaaaatg tacgagcaag cagccgcagc
    18481 acaacaagcc caggctggtg cagaaggtgc agcagataca ggctcaacaa acagtggcga
    18541 tgatgttgta gatggtgagt tcactgaaaa ataagctgtg aggagctaag gtcgctcagt
    18601 aaagctagaa actgaggcga tagtcccctc ccctaattgc tagaaaatag catagcaagg
    18661 ctaaataaat aaaaatcaaa taggcggggc gcctcgctcc gtctgttttt gtcaatgaag
    18721 gaaagaataa atgaataata cggaatacta tgatcgtctt ggggtctcaa aggacgcttc
    18781 ggccgatgat attaaacgag cttaccgtaa gatgtctaag aaataccacc cagacatcaa
    18841 taaagagccg ggagctgagc aaaaatataa ggacgtacag gaagcctatg aaaccctaag
    18901 cgattcacaa aagcgtgcag cctatgatca atacggggca gccggagcaa acggtggctt
    18961 tggtggtggc gcaggcggtt ttggcggctt cgatggtggt ggctttggcg gctttgagga
    19021 tattttctca agcttttttg gcggtggtgg tatgcgtaat cccaatgctc cacgtcaggg
    19081 cgatgacctt caatataggg taaacctttc ttttgaggaa gctgtttttg gtaccgaaaa
    19141 agaggtcagc tatcatcgtg aatcaacctg tagcacctgt gcaggctcag gagctaagcc
    19201 tggaacaagt cctacaacct gccgtaaatg tcatggctca ggggttatca atgttgatac
    19261 gcagacccca cttggcatga tgcgtcgtca ggtgacctgt gatgtctgtc atggcagcgg
    19321 tcaagaaatc aaagagcctt gccatacctg tcatggaact ggtcatgaaa agaaggttca
    19381 taaggtttca gtaaaaatcc cagcaggtgt tgaaaccggc caacaaatcc gcctacaggg
    19441 tcagggggaa gcaggcttta atggtggacc ttatggtgat ttgttcgtta ttttaaacgt
    19501 gcttccaagt aaacagtttg agcgcaatgg ctctactatt tactacagct tgaatatttc
    19561 atttgttcag gctgctttgg gagatacagt agatatccca acggtccatg gtgatgttgc
    19621 catgtctatt cccgctggaa cacaaactgg taaggtattt cgcttgaagg gcaagggggc
    19681 tcctaagctt cgaggcggag gccaaggaga ccagcatgta actgtaaaca ttgtaacgcc
    19741 taccaagctc aatgaggctc aaaaggaggc cttgaaggct tttgcggagg ctagtggcga
    19801 aaagccgatt gctccaaaga aaaaaggttt ctttgacaag gtcaaagacg ctctagagga
    19861 tatttaagcg ggtcttgttt acacactcta tgagcgattg atcacaattg tatagaatgg
    19921 ttgagcatag cacatgccaa agtttcagag tctaggacac ttttgtctta ggctctttta
    19981 ttagaggtat agaggctagg tctgagcttg gttttagggc tgcatgcttt aaattgcgca
    20041 gtcaatttta atgtattttt tacaatcttt ttcttgcata acgactgatt ctagtgtact
    20101 atagtctagt aattaatttg attgtcaaat tatttggtca taaaattatt tggtaatcaa
    20161 ataagctgtc agaaaagagg agtgatatga cgtttcaaaa tatcattttt gagcttgaag
    20221 aggatctggc cattttaacc ttaaatcgtc cagaggtgtc taatggcttt aacattccag
    20281 cctgtcagga gattctggag gctattaggt tggttaagga taacccctct ctgcgctttt
    20341 tagtgattaa ggcaaagggc aaggtctttt cagtcggtgg tgacttggtt gagatgcaaa
    20401 atgctgttga aagagatgat gttcagtctc tagttaggat tgctgagctg gttcaggata
    20461 tttcctttgc tatcaagcaa ttgccaaagc cggttatcct ctgtgctgat ggtgcggtgg
    20521 ctggtgcggc ctttaatatt gccttagcgg tggatttttg tattgctagc acccagacaa
    20581 aatttattca ggcctttgtt aatgtcggct tagcgccaga tgctggtggt cttttcttgt
    20641 taacacgtgc cgttggtcta aatagagcga ctcatctggt gatgaccggt gagggggtca
    20701 cagcagaaaa agggcttgag tacggatttg tctatcgagc tgctgagtca gataagcttg
    20761 ataagacctg tagtcagctg ttaaagcgtt tgaggcgtgg ctcttcaaat tcctacgccg
    20821 gcatgaaatc tttggtatgg caaagctttt ttgcaggttg ggaggattat gcccaaaaag
    20881 agcttgctat tcaagaggaa ttggccttta aggaggactt taaagagggc gtcagggctt
    20941 atggagatag gaggcggcca aattttcggg ggaaatagct cttatgtgct tgcaaaatac
    21001 tttgatgtct gatatacttt gatagtcaaa gtattttaca gctagggagg tgtttacttg
    21061 gaatataata agattaatca atatttagtt gatattttca acagaatttt ggttattgag
    21121 gaaatgagct taaaaacaag tcaatttaat gatgtttctc taaaggagat gcacacaatt
    21181 gagattattg gaaaatatca gcaggtaacg ccaagtgaca tcgcaagaga gctcatggtt
    21241 accttaggaa cggttaccac tagcttaaac aagctagagc taaagggcta tattgaaaga
    21301 acaagatcaa gcgtggatag acgggttgtt tacctgtcac tgaccaaaaa ggggcgtctt
    21361 ctggatcgtc tccatgcaag attccataaa aatatggtcg gtcatgtgat cgctgatatg
    21421 aatgaggacg aaatgcaagc cctgttacgt ggcttgggga acttacatca gtttttggag
    21481 gatttggttt aatggtcttt tcaaaaatta gtcaggtagc tcattatacg cctaagcagg
    21541 ttattagtaa tgacgatctg tcgcaaatca tggacaccag ccacgaatgg atttcgtcac
    21601 ggactgggat tgagaagcgt cacatttcca ctgtggagat gaccagtgat ttagccattc
    21661 gggtagcaga gcaattgtta gcagggtcag gatatgatgc gactgcactt gattttatca
    21721 tcgttgctac gattagccca gatgctagca tgccatcgac ggcagcaaag gttcaggctg
    21781 ctatcggtgc tactaatgca tttgcttttg atatgacagc ggcctgcagt ggctttgtct
    21841 ttgccttagc aatggcggat aagttgattg catcaggggc ttatcaaaga ggcttggtta
    21901 ttggagcaga gaccctgtct aagattattg attggcagga tagaagcaca gctgttttat
    21961 ttggagatgg tgctggtggg gttttattag aggccagcga gcagcagcat tttctagctg
    22021 aggccttaca tactgatggt gcgcaaggtc aaagcctgac atcaggtcag agcagtctgc
    22081 gctcaccatt ttctcaagga caggaggtca actcctttct tcagatggat ggtcgtgcta
    22141 tctttgactt tgcgattaga gatgtttcaa ggagcattac agcaattatt gagcaatcag
    22201 gcttggccaa ggaggagtta gactatctgc ttttacatca ggccaatcgg cgtattttag
    22261 ataagatggc taagaaaatt ggtatgccaa gagagaaatt tctggaaaat atgatgcact
    22321 atggcaatac cagtgcagct agtataccga ttttgctatc tgaatcagtc caaaatggac
    22381 agcttaaatt agacggcagc cagcatattt tactgtcggg cttcggtgga ggtttgacat
    22441 ggggcagtct aattgttaaa atctagttat atcatgtgcc tagcacattt ataaaataaa
    22501 tatttatatt aaggagacat aaaatggcag tatttgaaaa agtacaggaa attatcgttg
    22561 aggagcttgg caaggacgca gaggaagtaa ccttagaaac tacctttgat gatttagatg
    22621 ctgactcact tgatgttttc caagtgatct cagaaattga agatgccttt gacattcaaa
    22681 tcgaaacaga agaaggctta aacacagttg gtgaccttgt tgcctacgtt gaagaaaaaa
    22741 caaaataaag ctcaaacaag cgagaatact gattaaccag cctgctgatt aatgaactgc
    22801 tttagttggt caattgatat gtaataatcg aaccatcagg gtgagattag accctctttc
    22861 aggctctaac tcgctctttc ttcttattat gatagtttga ttatcaaatt attctcctga
    22921 tttctttgca tagaaggtta ttatgaaaac acgtattaca gaattactta atattgatta
    22981 tcccattttt cagggaggta tggcctgggt ggctgatggt gatctagcag gtgctgtctc
    23041 caatgctggt ggtcttggga tcattggtgg aggaaacgct cctaaagagg tggtcaaggc
    23101 aaatattgat cgtgtcaaag cgatcacaga taagcccttt ggggttaata tcatgctgct
    23161 atctcccttt gcagatgaca ttgtcgattt ggtgatcgaa gaaggtgtca aggtggtgac
    23221 cactggcgct ggaaatccag ggaaatacat ggagcgcctt catgaggcag gtattatcgt
    23281 gattccagtt gttcctagcg ttgccctggc taagcgcatg gaaaaattag gcgttgatgc
    23341 tgttattgct gaaggaatgg aggctggtgg ccatatcggt aaattgacaa cgatgacctt
    23401 ggttaggcag gtggtagatg ctgtttctat tccagttatt gcagcaggtg ggattgcaga
    23461 tggtcgaggt gcagcagcag cctttatgct gggtgctgag gctgttcagg ttggaactcg
    23521 atttgttgtg gcaaaggaat ctaatgctca ccaaagcttt aaggataaaa ttttgaaggc
    23581 taaggacatt gatactgtca tttcagctca agttgttggt catccggtac gctctatcaa
    23641 aaataagcta acatcagctt atgctaaggc tgaaaaagaa tttttagcag atcgtaaggc
    23701 tgctagtgac atcgaagaaa tgggagcagg agctctgcgc aacgctgtga ttgatggtga
    23761 tgtgatcaat ggctctgtca tggcagggca gattgcaggc ttaattagag cagaagaaag
    23821 ctgtgaagcc atcctaaagg atatctacta tggtgcagca gcagtgatta gtcaagaagc
    23881 taagcgctgg caagctcttg cagctgatga caaaaacgaa acgatataaa taaggagaag
    23941 tatgacaaaa acagcctttt tatttgctgg tcagggtgct cagacactag gcatgacaag
    24001 agatttgtat gaccaatatg ccattgctcg tgacaccttt gatcaggcta gtcagctttt
    24061 aggctatgat ttacgcaagc tcattgatac cgaccaggat cggttgaacc agacagccta
    24121 cacgcagcca gcaatcttaa ccgcttcagt ctccatttat cgtatcttaa cctcttatgg
    24181 ggttcatcct gatatggtgg cggggctttc tcttggagaa tattctgctc tagttgcggc
    24241 aggtgttctg agttttgaga ctgccctaga gctagttgca aaaaggggac gctttatgga
    24301 ggaggcagcg cctgctggct ctggtaagat ggtagctgtg atgaatacag aggctaggct
    24361 tattgaggag gcttgtcaag aggcttcttc ggttggtgtt gtgtcacctg ctaactataa
    24421 tacgccagga cagattgtta ttggtgggac agctgaggct gtcaatgcgg cacttgaaat
    24481 cttaaaagca aagggagtga agcgtttaat tccgctgaat gtctcaggac ctttccatac
    24541 agcactttta gcgcctgcta gtcaaaggtt ggcagaggag ctcagcaaga ttcaatttca
    24601 ggactttgat ctgccactgg ttggaaatac agaggctaag gtcatggaaa aggatcggat
    24661 tgcagaatta ttggcgcgtc aggtcatgga gcctgttcgt ttttatgata gtatcgaggt
    24721 tatgaaggct aacggtatca cccagtttgt tgagattggc cctggcaggg ttttaacagg
    24781 ctttattaaa aaaatcgaca aaaagctgct atgcagcagt gttgaagata tgccaagcct
    24841 acaattgtat ttgggaaaat aggagggaat gctaagctat ggaaattaaa ggaaaaaacg
    24901 tttttatcac agggtcaaca agaggcattg gactagcaat ggctcatcaa tttgcaggac
    24961 taggcgccaa catcgttctc aatggtcgct cagcgatttc tgatgagctg gtggagacct
    25021 ttaaggatta cggtgtgaag gttgtgccga tctcaggaga tgtttcagag ggggctgatg
    25081 ctaagcgaat ggttgatgag gctattgagc agcttggctc tgtggacatt ttgattaaca
    25141 atgctggcat cactaatgat aaattaatgc ttaagatgtc agaggaggac tttgagcgtg
    25201 ttctcaaaat caatctgaca ggagcattta acatgacaca atcggtctta aagccgatga
    25261 caaaggctcg tcagggtgct atcatcaatg tgtctagtgt tgtcggccta acaggaaata
    25321 tcggtcaagc aaattatgca gcgtccaagg caggcttgat tggctttacc aagtcagttg
    25381 ctcgtgaggt tgcggcgcgt ggcattcggg taaatgcgat tgcaccgggc ttcatcgaat
    25441 ctgatatgac aggtgtcctt tctgaaaaga tgcaagagca aatcttaaat caaatcccaa
    25501 tgaagcgtat tggcaagggg caagaggttg ctcaggcagc aagcttccta gctagtcagg
    25561 attatattac tggtcaggtg cttgccattg acggcggcat gacaatgcaa taaaatagag
    25621 gtattaaaat gacattaaac agagtagttg taacaggtta tggcgtgact tccccaattg
    25681 ggcatactcc agaggagttt tggtcaagct taaaggcagg tcatattggt attaagccta
    25741 tcacaaaatt tgatacgagt gacttcgctg ttaagaatgc agcagagatt caggattttc
    25801 catttgataa gtattttgtc aaaaaggatc taaatcgctt tgacatgtat tccttgtatg
    25861 ccttatatgc tgcgacagag gcgattgaac atgctggcct agatattgaa gcgattgatt
    25921 ctgaccgctt tggtgttatt gtagcgtctg gtattggagg cattcaagag attgaagagc
    25981 aggtgattcg gttacatgaa aaaggaccaa agcgcgttaa gccgatgact ctaccaaagg
    26041 ccttgccaaa tatggcggct ggtaatgttg ccatgaagct gaatgcccaa ggcgtatgta
    26101 agtcaatcaa tacagcctgt gcctcttcaa acgatgctat tggcgatgcc tttcgtacaa
    26161 ttaagtttgg tcttcaagac gtgatgatgg ttggaggatc agaggcagcc attacaaaat
    26221 ttgccattgc gggcttccag agcttgactg ccttgtcaac aactgaggac ccaagccgca
    26281 gctctattcc atttgataag gatcgaaacg gttttatcat gggtgaagga tcaggtatgc
    26341 ttgttttgga aagcttagag catgctcaaa agcgcggtgc gactatttta gctgagattg
    26401 ttggctacgg caatacctgt gacgcttacc acatgacctc accacaccca gaaggacttg
    26461 gtgctcgtaa ggccattaat ctagcattgc aggaggccgg tattgatgca gcagctattg
    26521 actacgtgaa tgctcatggc acctcaactc ctgctaatga aaaaggagaa agtcaggcta
    26581 ttgttgcagt gcttggtaaa gaggttcctg tctcatcaac caagtccttt acaggccacc
    26641 tactaggggc agctggtgct gtggaagcta ttgcaaccat agaagcaata cgtcacaatt
    26701 atgttccaat gacagctggg acaaaggagc tgtcagatga tattgaagca aatgttattt
    26761 ttggccaagg aaaagaagcc gatattcgtt atgccatgtc aaataccttt ggctttggag
    26821 gtcataacgc tgtattagcc tttaagcgtt gggaggatta aaatgaatat tcaagagata
    26881 aaggatttga tggcacagtt tgatgcgtca agcctacgcg aattttcatt caaatcaagt
    26941 gatggggagc tgttatttag taaaaatgag caccgtccga tggcagctcc agctcctgag
    27001 cctgttactt tgcaccagga ggtagcccct attagcctga cgcaggagat tgtctctaaa
    27061 caggaatcaa tccctgcttc ttcaggtctg caagagccag aaggagaagt agttgacagt
    27121 cctcttgttg gtgtggccta tcttgctgcc ggtcctgaca agcctccatt tgttactgtt
    27181 ggtgatagcg ttaaaaaggg acagacattg ttaattgttg aggcgatgaa ggtcatgaac
    27241 gagattcctg ctccttgcga cggtatcgtg acagagattt tagtggccaa tgaggacgtg
    27301 gttgagtttg gacaaggatt ggtacgcatt aaatgatgga tataaaacag attcaagagg
    27361 cattgccaca tcgctaccca atgctgcttg ttgatagaat tttagaggct tcagacgatg
    27421 aaattgttgc catcaaaaat gtcactatca atgagccctt ctttaacggt cattttcctc
    27481 agtatccagt catgccaggt gttttgatca tggaggcctt ggcacaaact gctggcgtct
    27541 tggagctatc aaaagaggaa aataaaggca agcttgtttt ttacgctggt atggacaagg
    27601 taaaatttaa aaagcaggtg gttccgggag accagctagt catgacagct aggtttatta
    27661 agcgtcgtgg gacaatagca gttgttgagg ccaaggcaga ggttgatggc aaattagcag
    27721 ctagtgggac cttgaccttt gcttttgggc agtaaaagac taatcgtctg tggaggaaaa
    27781 aagaacctat gtttaacaaa atcttaattg ccaatcgtgg tgaaatagca gtgcggatta
    27841 ttcgtgcagc acgagaatta ggcatttcca cagttgctgt ttattctgag gctgatagag
    27901 aggctttaca tacgatcttg gcagaccaag ccatctgtat tggaccgtca agatcaaagg
    27961 aatcctatct caatatgaat tctgtcttat cagcagctgt ggtgacaggg gcgcaggcta
    28021 tccacccagg gtttggtttt ttaagtgaaa attcaaaatt tgtgaccatg tgcgaggaaa
    28081 tgaacatcaa gtttattggc ccctcaggag ctgtcatgga taaaatgggc gacaaaatca
    28141 acgcccgcgc tgagatgatt aaggcaggtg ttcctgttat tccaggctca gacggcgagg
    28201 tttacaatgc ccaagaggct cttgagattg caaggcagat tggctatcca gtaatgctaa
    28261 aggctgctgc aggcggtggc ggcaagggaa tccgaaaggt tgaatccgag gctgatttag
    28321 aggctgcttt taacgctgct agtcaagaag ctttaggagc ctttggtaat ggtgccatgt
    28381 atttggagaa ggttatttat ccggcaaggc atattgaggt gcaaatttta ggtgattcac
    28441 aggggcatgt gatacacctt ggagagagag attgctcctt acagcgtaac aatcaaaagg
    28501 tactggagga aagcccttcg attgcgattg gcacaacact gcgtcaaagg atgggtgaag
    28561 ctgctgttcg tgctgccaag gcggtgtcct atgagaatgc tggcacaatt gagttcttat
    28621 tagatgaagc cagcggtgat ttttacttta tggagatgaa tacgcgtgtt caggtagagc
    28681 accccgtaac agagtttgtt acaggcgttg acattgtcaa ggagcaattg cggatcgcag
    28741 caggtcttcc tttatcagtt cgtcaagagg atattgtgat tactggccat gctattgagt
    28801 gtcgtattaa cgcagaaaat ccaagcttta attttgcacc aagccctggt aagattacag
    28861 atctttacct accaagcgga ggtgttgggc ttaggattga ttctgctgtt tacagtggtt
    28921 atacgatacc gccttattat gatagtatga ttgctaagat tatcgttcat ggagataacc
    28981 gatttgatgc tttgatgaag atgcaaaggg ctctgtttga gttagagatt gaaggtatta
    29041 tgaccaatat tgattttcag atggacttga tttcagacaa gcaagtgatt gcgggtgatt
    29101 acgatacgtc gtttttgatg gaaacctttt tacccagcta caataaagat taggagtaga
    29161 tatggcctta tttagtaaaa aagacaaata tatccgtatt actcccaata attctctcaa
    29221 aagctctgtc agtcgtaatg ttccagaggt gccagacgaa ttatttgcca agtgtcctgc
    29281 ctgtaagcac atgatttatc aaaaggatct ggggccggca aagatttgtc cgacctgctc
    29341 ctataatttt aggatttctg ctcaggagcg cttgacttta accgttgatg aaggctcttt
    29401 tcaggaattg tttacagata ttgaaaccaa ggatccatta agatttccag actaccaagc
    29461 caagctgcaa aaggccaggc aggctactgg cttgcatgag gctgtcctga ctggaacagc
    29521 tctggtcaag ggacaaaggc ttgctctagc catcatggat tcgcatttta tcatggcaag
    29581 catggggacc gttgttggtg agaaaatcac tcgcttattt gagctggcta ttagtgagcg
    29641 gctcccagtt gttattttta cagcgtctgg tggagcccgt atgcaagagg gcattatgag
    29701 tctgatgcag atggctaagg tttctgcagc tataaagaaa cattcaaatg ctgggctttt
    29761 ttacctgact atcctaactg atccgaccac aggtggtgtg acagcgagct ttgcaatgga
    29821 gggtgatatg attattgcag agccccagtc cttggttggt tttgctggtc gacgcgtcat
    29881 tgagacgaca gttagagaaa atttaccaga tgattttcaa aaggcagagt tcttaaaaga
    29941 gcatggcttt gttgacgcta ttgtgaagcg gactgacctg cgtgatcgga ttgctcattt
    30001 ggtggcattt catggaggtg tatcatgaca gacgtcgcaa gaatattaaa ggaagcgcgt
    30061 gaccagggtc gaatgacagc tctagattat gccagcctga tttttgatga gtttatggag
    30121 ttgcatgggg atcgtcagtt tgctgatgat ggctctattg ttggtgggat tgcctatttg
    30181 gctgatcaac cggtcacagt gattggtatt caaaaaggaa aaaatcttca agataatctg
    30241 gctagaaatt ttgggcagcc gcaccctgag ggctatcgta aggccttacg cttaatgaag
    30301 caggctgaaa aatttggtcg tccagtgatt acctttatca atacagcagg agcttatccg
    30361 ggcgtaggtg ctgaggagcg cggtcaaggt gaagctattg ctagaaactt gatggaaatg
    30421 agtgacctca aggttcctat cattgctatt attattggcg aaggcggctc aggcggtgct
    30481 ttagctttag ctgttgctga tcaggtttgg atgctggaaa acaccatgta cgctgttctt
    30541 agcccagaag gctttgcctc tattctctgg aaggatggct ctagggctac tgaagctgct
    30601 gagctcatga aaattaccgc agctgagctg tatcaaatgg gcgtcattga tcggattatt
    30661 ccggagcggg gttatttttc gagtgagatt gttgagatga taaaatcaca cttaattgac
    30721 gaaatcactc agctacaggc caagccctta gaggaattat tggatcagcg ctaccagcgc
    30781 tttagaaaat attaaggaca tcaaaaaaga cctctgtaag gctagcagtt agctaggagt
    30841 tacagaggtc ttctttattg ttaggatcaa tctcattaat cggctctttg tccccctaca
    30901 attgataaag agcctttttt gtacatagaa aaaagcccta tcatttctac tgtgtcctta
    30961 tctactacag aaatgataga gcccattaat cgtcttgttg gcaccttatc cggccagtct
    31021 ttggctttaa cgtggcttga tcacctctag tccacccata taaggacgaa gcacttctgg
    31081 aatcgtcact gagccgtcct cattttggta attttctagg atagcagcta cggtacgtcc
    31141 gacagcaagc ccagagccat ttagggtgtg cagtagctta accttgccat ctgcctcatc
    31201 gcggtagcga atttgtgcgc ggcgtgcttg gaaatcttcg gtatttgagc agcttgagat
    31261 ttcgcgatag gtgttttgag cagggatcca aacctctaaa tcataggttt tagcggccga
    31321 aaagcccata tccccagtac aaagagccaa gacacgataa gggagcttta gcttttggag
    31381 aatatgctcg gcattggcgg tcattttttc cagctcttca taagatgttt cgggcttagc
    31441 aaacttaacc atttcgacct tatggaattg gtgtaagcga atcaagccac gagtgtcgcg
    31501 gccagcagag ccagcctcag agcgaaatga tgggctcatt gcagtaaagt agattggcag
    31561 ctccttacca tctatgatgt caccacgata gtaattggtt aatgggactt cagcagttgg
    31621 gataagaaca aagtttgtcc catctagctc aaaggtatcc tccttgaatt ttggatattg
    31681 accagtgcca aacatagagt catgattaac catataagga ggaatgattt cttgatagcc
    31741 ctcttttagg tgctcatcaa gcatgaagtt ataaagggca cgctccagcc ttgcaccaag
    31801 atttttatag aataagaagc gagcaccggt aacctttgcg ccacgctccc aatcaaggat
    31861 atctaaggct tctccaagat cccaatgcgc cttgatgtca aaatcaaact gacgtggctt
    31921 tccccagcga tgaatctcta cattgtcctc ttcatcagct ccaataggaa ctgaatcatg
    31981 gggagtattt ggcaaaacag tgatgatacc ggtaatttct tggtcaatgt cagctagctt
    32041 agcatcaatt gccttgatgt tagcagctag ctgctgcatg tcagcaatct gttggctggc
    32101 gtcttccttt tggcgtttgg cttgagcgat agcagcagag gcgatattac gctgggcttt
    32161 tagctcttct gtttgaacaa gcagggtgcg ccgctgttca tctaaggctt ttagagaggt
    32221 taggatagct tctgacacac cacgtgtttt gagcttagca gcaacagtat caaaatcagt
    32281 acgaatacgc ttaagatcta gcataaataa atctcctttg agctggtgat aagatagtca
    32341 gttataaaat agcatgagca aagctagctg atcgcttttt tatttctgac gagataaaaa
    32401 agcacagcct atgaatacac tggagcgcct aagcgcggtt ccatccagct tcacaatctg
    32461 tgcacttaat tcatatttaa ttggtagacg gtagaatttc gtatgactcc tctatctgtt
    32521 ttcagcaacc acagactctc tgaaagacag agccagacta cttatccgct agacctatta
    32581 taacaaaaaa ggagaaaaag taaactccca aatgagtgtc agctacatca aacgcgcgaa
    32641 ctagttattt tggaattaga gtagacactt tcaatgtttt tcctatagta aagtctataa
    32701 aaaacaagac atatccttga aatacagaaa gctttctttt cttgctaaaa ctttttcatg
    32761 tgtctgtcac ggagcgtcag taatacaaaa ggctgatgac aagtagagct taggtcagag
    32821 gcacaaaaaa tctcgttgtc agacaaaatc aaatcgttaa atattaaaaa ttgtggtaaa
    32881 ctaatattat gcgtaaaaat gtaatgacat tagataagaa ccgccattac ggtttagatt
    32941 tattgcgaat catttccatg tttatgattg tgatcacaca tgttttggga aagggcggct
    33001 tgcggtcaac tgtcgaaggt gaggcagatt cttattttat tgttacctgg atgattcagg
    33061 ttcttgttta tggggcggtc aattgctatg cgttgattag tggctatgtg ggcattaagt
    33121 cgccctataa atattccaaa atcgttaata tttgggtaca agtcttcttt tatagctttc
    33181 tgatgaccct tttgtttgct ctatttggct ttccagttag cttagagaat tggcgtcagg
    33241 ccctctttcc catagtgagt ggcaattatt ggtatatcac cgcctacttt gggttactga
    33301 tttttatgcc tatgatcaat ggtggcctca ataccttatc caataagcag ctaggccgat
    33361 tggtactgct ggtttttgct attttttcgt tgatcccagc tctgatgaac cagcaggtcg
    33421 atgaattttc cttaagcaag ggctttgaaa tgacttggct gattattctc tacattatcg
    33481 gagcctatct aaggaggata gagctaagta ggtttagtca taagcttctt attgcggttt
    33541 atatgggatc tttggtagtt acctatatca tgaaatttat ggtgggaaat atttggtact
    33601 ggtatgtatc acctagcctg accttgggag ctattgcctt atttattctt tttgctaagc
    33661 tgaagctgac atcagaaaca ctgctgctac gctttattgt gatcgtgtct ccaacgactc
    33721 taggtattta tctggtgcac ttacacccct tgctggtcaa atttattatt cgcgattttg
    33781 cagagccctt tgtcaatgct cctatccttt tatacccact actgatattt ggcgtcggca
    33841 ttgtgattta ttttttgtcc tttctggttg aacaggcaag gctgatgctt tttaaaaaac
    33901 taggctttca aaatttgttg aaatgggtgg acaagaaaat cccctttgca gattgatgag
    33961 gaataaggtt agatttagat tgtagaaagg attcacttaa gcttgttttt caagcttttt
    34021 cttttaatca aaaaaacaaa agaattctga aaaatactgt aatatcagca ttttccagag
    34081 ttttcattat atgatagtca atttctaaat tttcaatttt tctatcgctg atagggtttg
    34141 tctacattct gtaagcttgt ttttcaagct tttttgttag caacgaaaaa aactcttaga
    34201 catattgcta tggtgctatg tctaagagta ttatcatgct ggtctatgac cgtaatattg
    34261 aattaaggca ggcccatcaa tgagatttct tatccttttt ttgatgatga aatagctttg
    34321 ctattatggt ctggaccaag gttggtagct tgatgacctt gtcattgcca attgtttctc
    34381 tagcaacctt caagattttt cctgaatcct ttgaagcaaa gagaaatttg ccttgatcgg
    34441 taaagatttc aaagtgacga ctgacctttt tgccagaaac attggcaccg atttggttaa
    34501 tggccgtcca gggaatttga atgaagtcct caacgttttt atcattgtaa aattccaaag
    34561 ccttatctcc aagtaagatt ttcccaacct ttcctccgat tccaagatag gagacggctg
    34621 ttgtctgaag gatcaccctt tgatttaaag attgtgccat aataagtcct ttagtgtttt
    34681 tgtctattat aacataaaaa tatagcttgt agcaggctga atactggcct ttgctaaggc
    34741 tctagacagc caaaaattaa ggaactggga agcccccaat tccttaattt ttattacatg
    34801 atgtgaagaa ggtgtgcgat gataccaaat gcaaacaagg caatgatgat tgcgattggt
    34861 gatacttttt tcttcaataa ccacatgcaa aggaaggtaa gtagtaatcc agcaagtcct
    34921 gggatcaatg agtctaattg cccttgaagg gtttgtgatt gaactttatc aaggctcatg
    34981 ccacccatag cttgtccaag aatacttttt agctcagcac ctttaacggc tccctcaggg
    35041 aagacaacat aggcaccttc agaaagctgc ttgcctggaa ggttgatggt aaagttgata
    35101 gatacccagc gttgtacaag gacagcaagg ataaacatac caaggataga agctccctta
    35161 gtgatgtctt gtaggatacc acctgacatg tctttggtga tttcagatcc agccttgtag
    35221 ccaaattctt gagtgtacca caagaaggcc atacggataa tgttccagcc aaagaagaaa
    35281 aggagtggac cgacaaggtt accagtttgt gcaagagaag caccaagagc accaaggata
    35341 ggacgcactg taaaccagaa gacaggatca ccgatacctg caagaggtcc catcataccg
    35401 atcttaaccc cttggatagc agcgttgtca atagcagtac cgttggcacg ttcttcttca
    35461 agggcaagcg ttaccccgat gataggagca gccacatatg ggtgagtgtt aaagaattcc
    35521 atatgacgct caagtgcagc agcacgatct tctttagttg tgtaaagctt tttaagtgct
    35581 gggataagtg cataagccca acccatgttt tgcatacgct catagttcca agacccttga
    35641 aggaattgtg aacgccacca aacacgttta cggtcagctt ttgttaattt aatttgttca
    35701 gtcattaatc ttaccccttt ctagtagtct tctaggatat cgccgattgg gtcagcagag
    35761 cctgctcgac ctccaccgtt accaccttgt tttgaaaggt taaggtagat aaaggcaata
    35821 gccacaccga taacacccat agcgataagt gttaattggg tcacagctgc aagggcaaaa
    35881 ccaagtgcga agaatggcca tacctcacgt gtagccatca tgttgataac aagagcgtaa
    35941 cctacggcaa caaccatagc accaccgatt tgcatacctt cattcaacca agctggcata
    36001 gccttcaaga cactttgaac ggcctcagtt ggcacagcaa caagaagtgc agctggtaca
    36061 gcaatacgca agccttgaag aagaagtgca gcaaagtgga agcgctcgat agcagagaag
    36121 ttaccctcta aagcagcctt gtccccagcg tgaacaagta cagttgaaat ggtacgaaca
    36181 atcatagtaa ggaaaagacc tgcaaccgca agaggaatag ctgttgagta tgcaaaggta
    36241 atcccttttt gagtaaagtc gccaccctta accatgataa tagccgctgc aacagatgca
    36301 agagcagcgt caggagctac agcagcacca atgtttgccc aaccaagtgc aagcatttga
    36361 agagtaccac caagcataac acctgcttca aggtgaccag tcacaagtcc gattaaggta
    36421 cacgcaacaa gtggttggtg catttgaaat tggtccaaga taccttcaag accggcaaag
    36481 aaggcaacga taacgaccaa gattgcagaa attaatgaaa tatctgacat tttgttatcc
    36541 tttcgtatat gagtcaattg tcaatggaca atataaagcg ttattaagtg atgatgattt
    36601 gtctagaagc aatcatcagg cttatcatat catcgcagca ttgtagatga ggcagacagc
    36661 ttgttgcgtt aaacaagcct acctcttatt tctaaattgc ttattgcaca tttgcttttt
    36721 ggataagctc aaataggttt ttcttagaat catttggcac cttacgaacg tcaaatgaaa
    36781 cacctagatc acgtaatttt tcaaaggcag caacgtcatc cttgtccata gacaatacgt
    36841 tgttaaccat tgttttacct gttgaatgcg ctattgatcc aacgttcagc tctttgatct
    36901 caacgccgcc ttcaatcgca cgaagggcgt cctgaacagt ttcaaacagg ataagagcgt
    36961 gagtgttgcc aaagcgtggg tccttagaag cctcaatcaa tttattgatc ggaacaacat
    37021 tagccttaac cccaccagga gccgcctgct tgatcaattg cttacgaagc tcgtccttag
    37081 ccacagaatc tgacgctaca ataatacgat cagccttaga agctggtgtc catgcagttg
    37141 ctacctgacc atgaagaaga cgagtgtcaa tacgagcaag gttgattttt agcttaccat
    37201 ctccaatgac agttccctta ggaatagctc cttgaagcgc ttgaccacca ccattagctg
    37261 tagaagcctc ctcaactgga ttgagctctt caggaagggc tttaataccg tccttagatt
    37321 ctttaatgat gtttgcggct acttgttcaa cacctgcatt ggcgtccatc aaacgctcag
    37381 tataggcttg aataagcatt ggcaaattta gaccagtgat gatagccatt ttgcgatcag
    37441 gattttctcc tgccacacga ctagcctgat taaatggaga accactccaa aggtcagcta
    37501 gtacaaggat ttcatcatca gcatcaaatt gtgcgatagc attgttgaag tgtccataca
    37561 agtcatctgg tccttcattt ggcatgaaag tcacaacttg aactttctct tgttcaccaa
    37621 aaatcataga accagattga tgaatacctt cagcaaattt accatggctg gcaataataa
    37681 taccgatacc cattcttgtt cttcctcctt attaaaatat ttttcgttga aatgaagaag
    37741 aataatctcc ttccaaatag catttggcaa ttctttttca cttgaacgaa attcaagaac
    37801 gtctctattt taaaacgttt tcacttaaaa atcaagccct ttcggaaaaa tcttacgaaa
    37861 tatgaaaaaa ttttcataat gc
//
LOCUS       DARYXW010000009        35713 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.009, whole genome shotgun sequence.
ACCESSION   DARYXW010000009 DARYXW010000000
VERSION     DARYXW010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35713)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35713)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35713
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.009"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            <1..693
                     /locus_tag="TV191_000366"
     CDS             <1..693
                     /locus_tag="TV191_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1506916.1"
                     /translation="TDDSFIAVFDPKLKEIDKHIFEDSVIASDFSVDGDDIYLLGTDV
                     KIKDNYPTYLYTLSIKNGQLAMKNKELLYEQPESTYFFHDSIVKEKQLYTALSGYRNN
                     VTKERTVLGQVFHYDMQSGQKHFFDLTEIAPVNIFDLGHDTLAIEHEKNEAGKIGFSL
                     FHLNDKTSTFIDLSQFGLSIESDYLKDVKQIDENTLLILAGHTLIGYHINDHQAIFNK
                     QVSDDAFHIWVK"
     gene            complement(1204..2832)
                     /locus_tag="TV191_000367"
     CDS             complement(1204..2832)
                     /locus_tag="TV191_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1506917.1"
                     /translation="MNWSTIWELVKINILYSNPQSLTALKKKQEKAPKENFKAYKSMI
                     RQQALMIALFLVIYIFMFMGVDFSQYPGLLSLYIAIFFVMATVNAFTAMYAVFYESND
                     VKLYVHLPIRSEELFIAKLISSLGMGSIFLMPLLSLFVIAYWQIIGNALAIVLAFILF
                     VVLFVSSIVFALYLNAWIGRIILRSSKRRLISAVLMFASTFGALGLIVFLNMTNNQRM
                     MADQAFSDRPLIPYFRGSYDVVVAPFSSQALLNFWLPLLLVMLMLYGLVRRIMPAYYR
                     ETLYVGGKAKNAAVARKAAASDRQQSLQRLLTKHHLATLQNATLLTQTYLMPLIYVMI
                     FITPSVTSGAQFSSYITDEYFGIALLVGVLLGSICTVPTSFVGVGISLEKDNFTFIKT
                     LPISLKGFLLNKFRLLIGLQILAPLVVYALIGLFVLGFHPVIVLSFSLGFVLMGIIQG
                     QLMFRRDYRMLDLKWQDVTQLFTRGNSQWFMLGLMFGDLIVGGFLIVLAIMCATISQQ
                     PLLVSIAVSLILLSCLLFAQLWIQRSFWKNLNKM"
     gene            complement(2837..3568)
                     /locus_tag="TV191_000368"
     CDS             complement(2837..3568)
                     /locus_tag="TV191_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1506918.1"
                     /translation="MIEFRHVSKLYGDKEALSDVSLTIKDGEIFGLIGHNGAGKTTTI
                     SILTSIIEASYREVLVNGQLLSEHRNTIKRQIGYVPDSPDIFLNLTAYEYWQFLAKIY
                     GVSEADTKARIEELTQLFELTQEMHNTIDNFSHGMRQKVIVIGALISNPSIWILDEPL
                     TGLDPQASFDLKEMMKEHAASGNTVLFSTHVLSVAEQLCDRIGILKKGKLIFVGTVEQ
                     LKADYPDKDLETIYLELAGRQAQEA"
     gene            complement(3605..3862)
                     /locus_tag="TV191_000369"
     CDS             complement(3605..3862)
                     /locus_tag="TV191_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL1506919.1"
                     /translation="MEKEQQRLYDVIKQAYDYPENRANSHLARLLLSASNQLIKNSNP
                     LTIAEQLNQALDDYLQANDLLLPKSLCGFKQSLDAYLLEKG"
     gene            4233..5681
                     /locus_tag="TV191_000370"
     CDS             4233..5681
                     /locus_tag="TV191_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1506920.1"
                     /translation="MINKRKKKLIYRYGVCSAAVILAALASLGTCKEAKALSGPPGYP
                     LTRDFSRNFLEENTAKYLDQLREHLQHRFSELESLTRKLEKEGGTRGPAGPPGPAGPK
                     GERGEPGPVGPMGPRGEQGPKGLDGARGPEGQQGKPGPVGPQGPAGPAGQKGETGPQG
                     PRGDKGDTGETGKQGPAGERGPAGPQGPRGDKGENGAPGEQGPIGPKGETGPKGDKGE
                     RGEKGDQGQRGEKGDQGQRGEKGDQGQRGEKGEQGQRGEKGEQGQRGEKGEQGPRGEK
                     GEQGPRGEKGDQGQRGEKGDQGQRGEKGEQGQRGEKGEQGPRGEKGEQGPRGEKGEQG
                     QRGEKGDQGQRGEKGDQGQRGEKGDQGQRGEKGDQGQRGEKGEQGQRGENGEQQPKGD
                     QGKDTKPSVPKAPESPKMPEKPQAPEKAPAPKAPKASEQSASPKAPAPQSTPSKKAVL
                     PATGEASHPFFSLAALSVIASAGLLTLKRKKS"
     gene            complement(5863..7851)
                     /gene="tkt"
                     /locus_tag="TV191_000371"
     CDS             complement(5863..7851)
                     /gene="tkt"
                     /locus_tag="TV191_000371"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEL1506921.1"
                     /translation="MTFDAIDQLAVNTVRTLSMDAIQAANSGHPGLPMGAAPMAYVLW
                     NHVMTVNPKTSRRWSNRDRFILSAGHGSAMLYSLLHLAGYDVSIEDLKNFRQWGSKTP
                     GHPEVNHTDGVEATTGPLGQGVANAVGMAMAEAHLAAKFNRPGFDIVDHYTYALNGDG
                     DLMEGVSQEAASLAGHLKLGKLVLLYDSNDISLDGPTSMAFTEDVKGRFEAYGWQHIL
                     VKDGNDLEAIAKAIEEAKAETEKPTIIEVKTIIGFGAEKQGTSAVHGAPLGAEGIAFA
                     KKSYQWTHADFEVPQEVTERFRQGLQARGEQAEQAWNDLFAAYEAAYPELAAEYKKAF
                     ANEAAEVELQAHELGTAVASRVSSQQAIQQISEQVPAFWGGSADLSASNNTMVKAETD
                     FQPGHYAGRNIWFGVREFAMAAAMNGIALHGGTRVYGGTFFVFSNYLLPAVRMAALQQ
                     LPTVYVMTHDSIAVGEDGPTHEPIEQLASVRSMPNLNVIRPADGNETNAAWKRAIAET
                     DRPTMLVLTRQNLPVLEGTKELAEDGLNKGAYILSEAKGDLDGIIIATGSEVKLAMDT
                     QAALAADGIHVRVVSMPSQNIFDEQPASYKEEILPAAVTKRLAIEAGSSFGWAKYVGL
                     AGKTLTIDTWGASAPGNRIFEEYGFTVEHATELYKSLS"
     gene            complement(8235..8879)
                     /gene="fsa"
                     /locus_tag="TV191_000372"
     CDS             complement(8235..8879)
                     /gene="fsa"
                     /locus_tag="TV191_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEL1506922.1"
                     /translation="MKFFLDTANVEAIRAINELGVVDGVTTNPSIISREGRDFETVIK
                     EICEIVDGPISAEVTGLTAEEMIAEARNIAKWHDNVVVKIPMTTEGLKATNVLSQEGI
                     KTNVTLIFTVSQGLMAMKAGATYISPFIGRLEDIGADPYQLISDLRGIIDLYGFQAEI
                     IAASIRTAAHVEAVAQLGAHIATIPDPLFAKMTEHPLTTNGLKTFMEDWASFKK"
     gene            complement(9053..10558)
                     /gene="glpK"
                     /locus_tag="TV191_000373"
     CDS             complement(9053..10558)
                     /gene="glpK"
                     /locus_tag="TV191_000373"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEL1506923.1"
                     /translation="MGTETYIMAIDQGTTSSRAIIFNKKGEALVSSQKEFPQLFPQAG
                     WVEHNANHIWNLVQSVIADAFIESGIKPEQIEAIGITNQRETTVVWDKQTGLPIYNAI
                     VWQSRQTASIAEQLKRDGYTKMIHEKTGLVIDAYFSATKLRWLLDHVPGAQERAERGE
                     LLFGTIDTWLVWKLTDGAVHVTDYSNAARTMLYNIKELKWDDEILALLNIPKAMLPEV
                     RSNSEIYGKTASFHFYGGEVAIAGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GQEAQLSSSNLLTTIGYGINGKVYYALEGSIFIAGSAVQWLRDGLRMIKTSFESEQLA
                     LASTNADEVYVVPAFTGLGAPYWDSNARGSVFGLTRGTTKEDFVKATLQSIAYQVRDV
                     IDTMQVDSGITIQQLRVDGGAAMNNMLMQFQADILGIDIARAENLETTALGAAFLAGL
                     AVGYWKDMETLKQLNATGQLFKASMSESRREKLYQGWKRAVKATQFFAEEL"
     gene            complement(10898..11491)
                     /locus_tag="TV191_000374"
     CDS             complement(10898..11491)
                     /locus_tag="TV191_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HEL1506924.1"
                     /translation="MIIKKLSVIALTSLSLISLSACRQQNQALGQNGSAQNHRKASVS
                     EDKAKELAFKDASITAADAQRLKLTKETDDGRVVYDIEFDAKDQEYSYTIDANTGEIL
                     EKSSEPITEAPASAQAAGGQADQAAGISEDKAKELAFKDASITAADAQRLKLTKETDD
                     GRVVYDIEFDAKDQEYSYTIDANSGDILEKSSEPVYD"
     gene            complement(12159..12359)
                     /locus_tag="TV191_000375"
     CDS             complement(12159..12359)
                     /locus_tag="TV191_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEL1506925.1"
                     /translation="MEHYRALAISEMQDISGGNAAGNAVIGGLGGLKTGITFCKIPHP
                     VLKGVCIDGFTALGACLAYKVN"
     gene            complement(12418..12573)
                     /locus_tag="TV191_000376"
     CDS             complement(12418..12573)
                     /locus_tag="TV191_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEL1506926.1"
                     /translation="MATEMLASFEGGKNNWAANVSGVIGAGSAGAALGFPVCGVACGS
                     IGVTGGF"
     gene            complement(13079..13945)
                     /gene="rsmI"
                     /locus_tag="TV191_000377"
     CDS             complement(13079..13945)
                     /gene="rsmI"
                     /locus_tag="TV191_000377"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEL1506927.1"
                     /translation="MQIQKSFKEEKESGVLYLVPTPIGNLEDMTFRAVNVLKEVDIIC
                     AEDTRNTGLLLKHFGIKTKQVSFHEHNAYDKIPDLLDLLLAGRSLAQVSDAGMPSISD
                     PGHELVRAAIDRDITVVALPGASAGITGLIASGLAPQPHLFYGFLPRKAGQQRAFLMT
                     KADYPETQIFYESPYRVKDTLTNLLACYGDRQVVLVRELTKLFEEYQRGQISEVLTYL
                     ADHPLKGECLLIVAGANQADASEPAEDLDLLALVQQAIAAGMKPNQAIKTIAKDYKVN
                     RQELYQQFHGLG"
     gene            complement(13950..14273)
                     /gene="yabA"
                     /locus_tag="TV191_000378"
     CDS             complement(13950..14273)
                     /gene="yabA"
                     /locus_tag="TV191_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEL1506928.1"
                     /translation="MNKKELFDAFDGFSQNLMVTLAEIEAMKKQVQGLVEENTILRLE
                     NTKLRERLSQLEHENLAKTSSKQGKDHLEGIYDEGFHICNFFYGQRRENDEECMFCRE
                     LLDRK"
     gene            complement(14266..15066)
                     /locus_tag="TV191_000379"
     CDS             complement(14266..15066)
                     /locus_tag="TV191_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEL1506929.1"
                     /translation="MISTIGIKYCDTCSVRYVQTDQAFPVQTKLVISDGKGSRLAVVN
                     SPIKSFCKDDLPKDMPSVLRPANDMDYKAYQQNLQLAAQSKQKVAEMIDRNGLDMTLV
                     DIVFSLERRYVLITFTAQERVDFRQLLKDLAAYFKTRIELRQINSREEARVYGGLGPC
                     GRPLCCSSFLGEFPPVSIKMLKHQGLSLHSAKSLGCCGRLLCCLQYEDDFYQESKKKF
                     PDYGTIVRTAQGPGEVAGIDLFTDTIQVRFKDQLALVTYALEEVKVSE"
     gene            complement(15063..15938)
                     /locus_tag="TV191_000380"
     CDS             complement(15063..15938)
                     /locus_tag="TV191_000380"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEL1506930.1"
                     /translation="MDLAQKAPRVYQAFQEILQKKRLNHAYLFSGDFANFDMALFLAK
                     TLFCEQKRGNAPCHHCRACQLIEHNDFSDVTILEPVGQLIKTDTVKEMMTNFSQTGYE
                     GRRQVFIIKDCDKMHVNAANSILKYIEEPQGDCYMFLLTNDDNQVLPTIKSRTQVFHF
                     PKDEHYLSELAQKKGLLKHQADLLARLAANAQQLTAFSENTRLLELMAQAERFVSIWF
                     QDKEQAYLELNRLVQLAEEKEEQDMALTLLTLILAKDYSRQNAFTYLEAVYQARLMWQ
                     SNVSFQNTLEYMVIS"
     gene            complement(15952..16587)
                     /locus_tag="TV191_000381"
     CDS             complement(15952..16587)
                     /locus_tag="TV191_000381"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEL1506931.1"
                     /translation="MTRGKLITFEGPDGAGKTTVLERLVPLLQAALGQTIVTTREPGG
                     VAIAEKIRQLILDVSHTTMDDKTELLLYIAARRQHLVEKIMPALESGHLVLVDRFIDS
                     SVAYQGAGRGLDKQAIQWLNHFATDGVDPDLTLYFDVPSELGLARIAQNTEREINRLD
                     LEQLDLHQRVRKGYLELALENPQRIVKIDASQDLESVVSAALAAIITHSQA"
     gene            complement(16903..17187)
                     /locus_tag="TV191_000382"
     CDS             complement(16903..17187)
                     /locus_tag="TV191_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEL1506932.1"
                     /translation="MFQKQQRIGLVIYLYYNRDARKVMKYGDLYYHSRRSRYLVIYIN
                     KEDMEEKLKDISRLTFVKEVKVSAFDDIDCDFVGNLHREPLEPQALPEQG"
     gene            complement(17188..17634)
                     /locus_tag="TV191_000383"
     CDS             complement(17188..17634)
                     /locus_tag="TV191_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HEL1506933.1"
                     /translation="MLIINEELFAIEKAIEQLVQDIRTSSQYQAYALAKKAFEADLAL
                     QTELALFEELKQDYELRQDLLKLCPDARALRCQLLHQKRQLDLHPLVADLRLAQVDLQ
                     EVLATISTAIAEAVSEDILVDTGLPLATNRPRHELGPYQNIKEKST"
     gene            complement(17739..18329)
                     /locus_tag="TV191_000384"
     CDS             complement(17739..18329)
                     /locus_tag="TV191_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HEL1506934.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHRLEKILAQNAGK
                     TIKQIHKDAERDYWMSAEETLAYGFIDEIMENNELA"
     gene            complement(18560..19189)
                     /gene="upp"
                     /locus_tag="TV191_000385"
     CDS             complement(18560..19189)
                     /gene="upp"
                     /locus_tag="TV191_000385"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEL1506935.1"
                     /translation="MGKCQVISHPLIQHKLSILRRQDTSTKDFRELVNEIAMLMGYEV
                     SRDLPLEDVEIQTPVAKTVQKQLAGKKLAIVPILRAGIGMVDGFLSLVPAAKVGHIGM
                     YRNEETLEPVEYLVKLPEDIDQRQIFIVDPMLATGGSAILAVDSLKKRGAANIKFVCL
                     VAAPEGVKKLQEAHPDVDIYTAALDERLNDHGYIVPGLGDAGDRLFGTK"
     gene            complement(19339..20970)
                     /locus_tag="TV191_000386"
     CDS             complement(19339..20970)
                     /locus_tag="TV191_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEL1506936.1"
                     /translation="MSTEKKQLTQEQLMVQGAAWSTAGNFISRLLGVLYIIPWYIWMG
                     QYAIQANALFNMGYNVYAYFLLISTTGLNVAIAKQVAKYNSMGQQEHSYQLIRSTLKV
                     MLVLGLIFSVLMYLGSPLFARLSGGDETLVPIMHSLSLAVFVFPVMSVIRGIFQGYKE
                     IKPYALSQIAEQLVRVIWMLLTTFFIMKMGSKDYIAAVTQSTFAAFIGMIASMAVLFY
                     YFWTQGLLKAIFTKTEHAIPIDIKGLLIETLKESIPFIITGSAIQAFQLLDQWTFVNT
                     MTLFTSYTRSQLWVLFGYFNANPAKITMVLIAVAASIGSVGIALLTENYIKKDMRAAG
                     RLIINNIEMLLMFLLPALTGAIILARPLYTVFYGSSEGQAVRLFVAVLCLTLLMALYT
                     LFSPMLQALFENRKAIYYFAYGVFVKLVLQVPLIYLFHAYGPLLATTLGLLVPIYLMY
                     RRLHQVTRFNRKLLHKRILLTVIETALMGLIVLLANWFLGYLFKPTGRLTSLLYLVII
                     GGLGMGVYAYMTLLTRQLDKLIGSRAARYRQKLGL"
     gene            21056..22501
                     /locus_tag="TV191_000387"
     CDS             21056..22501
                     /locus_tag="TV191_000387"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEL1506937.1"
                     /translation="MITIEHLLTILKKDHNFREVLDQDGYHFNYSGLQFDSLSYDSRQ
                     ADEQTLFFAKGSAFKADFLRQAIAKGLRLYVSEIDYQVGIPVILVNNIKHAMSLAAMA
                     FYDYPQNKLKLLAFTGTKGKTTAAYFAYHMLKESHKPALLSTMNTTLDGQHFFKSQLT
                     TPESLDLFAMMAQCVANGMTHLVMEVSSQAYLVGRIYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVVVNSGMEHFNILAEQVADKPHDFYGKGACNRLLQRQA
                     FSFQAAGKVAGDYAIQLIGSFNQENAMAAGLACLRLGASLEDIRQGIAKTNVPGRMEV
                     LTMTNQAKVFVDYAHNGDSLEKLLSVVEEYQKGQIYLILGAPGNKGESRRADFGQVIN
                     QHPNVRIILTADDPNFEDPQLISEEIASYIHREVDIIIDRKEAIKTGMERCQNEQDAL
                     IIAGKGADAYQIVKGQKTAYAGDLAIAKSYL"
     gene            22761..23540
                     /locus_tag="TV191_000388"
     CDS             22761..23540
                     /locus_tag="TV191_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1506938.1"
                     /translation="MSTISAERISAGYDQSLIISNLSVTIPEGKVTTIIGANGCGKST
                     LLKTLARLLPLKAGQVLLDGQAIARLATKDVARTLAVLPQLQEATTATVYELVSYGRY
                     PHQSYLGQLSQADKDKICWAMEVTSMAPYAHQAVDALSGGQRQRAWIAMALAQDTDII
                     FLDEPTTYLDMNHQLDILELLKELNQVSGKTIVMVLHDLNLSARYSDHLIAMKNGHIK
                     YSGEVNQVMTPEMIQDIFQVKAQLVTDPLYHCPTLLTYQLI"
     gene            23565..24503
                     /locus_tag="TV191_000389"
     CDS             23565..24503
                     /locus_tag="TV191_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-hydroxamate ABC transporter
                     substrate-binding protein"
                     /protein_id="HEL1506939.1"
                     /translation="MKKLLLILTVFVTAFTLVACSSQSKQQESTSKASLSHKPKIAGV
                     TYYGDIPVKPKRVVSLAATYTGYLAKLDLHLVGVTSYDKKNPVLTKSITQAKQVAATD
                     LEAITALEPDLIVVGSTEENIDQLAKIAPLISIEYRKRDYLQVFSDFGRIFNKEKETD
                     QWLADWKQKTSDYEKEIKQVTGSAATFTIMGLYEKEIYLFGKDWGRGGEIIHQALHYD
                     APEKVKKEVFKQGYLSLSQEVLPDYIGDYVIVAAEDDQTGSALYESDLWQQIPAVTNN
                     HVIKVNANVFYFTDPLSLEHQLEVLKKAILSTGASQ"
     gene            24513..25538
                     /locus_tag="TV191_000390"
     CDS             24513..25538
                     /locus_tag="TV191_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEL1506940.1"
                     /translation="MTAQHHTKPKLAKAAPPWLILTFISLTLVLAIYCSLRFGAVSLS
                     HQELYHILLGKQDQGQKASIILDIRLPRLILAALVGAALAVSGAIMQGITRNPIAEPG
                     LLGINSGAGLALVIGYAFSPHLHYSTIILLSLLGSLLATLLILSLAYQAGKGYTQMRL
                     ILAGAMISMLLSAIGQGITTYCHLANAIIGWQAGGLIGVNWQMVSYVAPLIICGLALS
                     YLLAYHLTILSLSQEQAKALGQRTFLISLIFIGLVLLLSSAAVAVAGSISFVGLIIPH
                     AITLVTAKDYRWILPLATLLGASFMLWVDFACRNINPPYETPLSALISFIGLPCFLWL
                     VRKGGRF"
     gene            25535..26533
                     /locus_tag="TV191_000391"
     CDS             25535..26533
                     /locus_tag="TV191_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEL1506941.1"
                     /translation="MTATKRHVPLFLGLISGLVCLMIISLSIGESSMSPLEVVRVLFG
                     KSTADMALIITNIRLPRILAACIGGGSLALSGLMLQSLTRNHLADSGILGINAGAGMA
                     ITLVISYSTSNSLTSRQGLPLMTISGAMATIVLVYLLSLRHGHIDPIRLIVTGVGLST
                     MLSSLMIAFVGNVNRYKVDYVIHWLSGQLTGDDWSKLSIVAPLLGITWLLAFSQAYKL
                     NIMALNDEASMALGFKLHQYRTIVLALSAILSALSVILVGNITFIGLIAGHTSKRLVG
                     ADHRLSLPVSLFIGMILLLLADTIGRVYLVGSNIPTGILVSIIGASYFLYLMVKMT"
     gene            complement(26638..27291)
                     /locus_tag="TV191_000392"
     CDS             complement(26638..27291)
                     /locus_tag="TV191_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEL1506942.1"
                     /translation="MITIFNPDKLTRQPFFQDLIHYLNQHDDVTLRHIKQAFSHVKGI
                     DKALEAYIQAGYICRKNRRYYLCLPLLDDLQQVTLEDLIFVDRASDLYEALMALVFET
                     VLSNQTNQVLIKEKTTIDRDKLTLANYFYRLRRGEALSDEQLRLYALLGDVNQDYALK
                     YMTSFLLKFARKEIVMQKRTDIFVNALELLGYIEKVEATKYCLKLAFDKEQLIFYAD"
     gene            complement(27358..28293)
                     /locus_tag="TV191_000393"
     CDS             complement(27358..28293)
                     /locus_tag="TV191_000393"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEL1506943.1"
                     /translation="MSKLLVFGHQNPDTDAIASSYAFDYLAKKAFDLDTEVVALGDPN
                     EETAFALDYFGVSAPRVVTSAKAEGASHVILTDHNEFPQSISDIREVEVYGIVDHHRV
                     ANFETANPLYMRVEPVGSASSIVYRLFKENRVDVPKDIAGMLLSGLISDTLLLKSPTT
                     HASDHRVAAELAELAGVKLEEYGMAMLKAGTNLASKSEAELIDIDAKTFELNGNAVRV
                     AQVNTVDIAEVLERKEAIEAAIREVMASEGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFSFKLEDNHAFLAGAVSRKKQVVPQLTESFGA"
     gene            complement(28793..29584)
                     /gene="pflA"
                     /locus_tag="TV191_000394"
     CDS             complement(28793..29584)
                     /gene="pflA"
                     /locus_tag="TV191_000394"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEL1506944.1"
                     /translation="MVEVDYGQVTGMVHSTESFGSVDGPGIRFIIFLQGCKMRCQYCH
                     NPDTWAMETNQSQRRTVNDVLKEALQYRHFWGKKGGITVSGGEAMLQMDFITALFTEA
                     KKLGIHTTLDTCGFAYRPTPEYHELLETLLAVTDLILLDLKEIDEEQHKLVTRQPNKN
                     ILQFARYLSDRQVPVWIRHVLVPGLTDIDDHLVRLDAFVKTLRNVDKFEVLPYHTMGE
                     FKWRELGIPYQLEGVKPPTKERVENAKKLLHTESYTEYMNRIHQS"
     gene            complement(29661..30995)
                     /locus_tag="TV191_000395"
     CDS             complement(29661..30995)
                     /locus_tag="TV191_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEL1506945.1"
                     /translation="MEDPVSQPLLIQFLLLVILTLLNAFFSASEMALVSLNRSRVEQK
                     AADGDKRYDRLLRVLEQPNNFLSTIQVGITFISLLSGASLSASLGQVISGWLGGSATA
                     QTAGSIISLVFLTYVSIVLGELYPKRIAMNLKDKLAVISAPVIIILGKLVSPFVWLLS
                     ASTNLLSRITPMTFDDADERMTRDEIEYMLTNSEATLDAEEIEMLQGIFSLDEMMARE
                     VMVPRTDAFMIDINDDTLDNIKEILKQSFSRIPVYDVDKDKVIGLIHTKRLLESGFRQ
                     GFENISMRKLLQEPLFVPETIFVDDLLRQLRNTQNQMAILLDEYGGVAGLVTLEDLLE
                     EIVGEIDDETDKAEQFVHHIDDNTYIVTGTMTLNDFNEYFDTELESDDVDTIAGFYLT
                     GIGTIPSQKEKESFACDSKQKHLVLVNDKVKDGRITKLKLTISNIEQNITED"
     gene            complement(31123..31680)
                     /locus_tag="TV191_000396"
     CDS             complement(31123..31680)
                     /locus_tag="TV191_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1506946.1"
                     /translation="MIKRPIHVSHEFLKEVLDKQSIAVDATMGNGYDTAFLASLSQRV
                     YAFDVQQQALTKTQERLEQQGLTNAELILAGHEQVDQYVKEPIRAAIFNLGYLPNADK
                     SLITRPETTILALAKILDRLELGGRIAIMVYYGHDGGSREKEELLDYIGQLNQRQVTA
                     MLYQPINQMNQPPFLIMLEKIAATD"
     gene            complement(31690..32475)
                     /locus_tag="TV191_000397"
     CDS             complement(31690..32475)
                     /locus_tag="TV191_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 3'-phosphotransferase"
                     /protein_id="HEL1506947.1"
                     /translation="MKQRLIAGEELSLPPVLKKLLQNSLVYDSSSSAEARVYAIDKGQ
                     GYFLKTAAKGRLAKEAALTRYCHSKGLATEVLDYISGDQDWLLTAKVAGEDASHIEYL
                     SDPKRLCRILVDHMLKLHSLSLSDFPVADKTLAYIEAAEAGYHQGRFNQCFLPPQQRF
                     QSQEEAYRRIQELKLLLQHETLIHGDFCLPNMILDRWQFQSMIDWGEAGKSDRHIDLF
                     WLIWSLQFNLKTDRYKDYVLDCYGRRHIDLDILDGIAAFEVFA"
     gene            complement(32488..33411)
                     /locus_tag="TV191_000398"
     CDS             complement(32488..33411)
                     /locus_tag="TV191_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623410.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HEL1506948.1"
                     /translation="MTKRYQTLNEYYRRLFGAKIFKVPIDAGFDCPNRDGTVAHGGCT
                     FCTVSGSGDAIVAPDAPIREQFYKEIDFMHRKWPEVNQYLVYFQNFTNTHDKLEVIRE
                     RYEQAINEPGVVGINIGTRPDCLPDETIAYLAELSERMHVTVELGLQTTYEATSQLIN
                     RAHSYDLYKETVQRLRQYPNINIVSHLINGLPGETHEMMIENVRRCVTDNDIQGIKLH
                     LLHLMTNTRMQRDYHEGRLQLLSQKDYVSIICDQLEIIPEHIIIHRITGDAPRDMLIG
                     PMWSLNKWEVLNAIDLEMERRNSWQGCKLKG"
     gene            complement(33602..34252)
                     /locus_tag="TV191_000399"
     CDS             complement(33602..34252)
                     /locus_tag="TV191_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEL1506949.1"
                     /translation="MKHKQQHLLLSSFAMLLFVVLGYIVKFFPEDLTSFDSQLRLALR
                     GHLPEGLTQFFKGITVAGNVSTQAVIVVVAVLALLALSWRAEALFVLSNGVFAALLIW
                     VLKLLYQRPRPSIEHLVHASGYSFPSGHSMGSLLIIGSLLIICHQRLQSASLRWLVDI
                     ALLALILLIGLSRIYLGVHYPSDVLAGYALGFGILQLLYPFYDQKRFEWRFQLKQK"
     gene            complement(34242..34820)
                     /locus_tag="TV191_000400"
     CDS             complement(34242..34820)
                     /locus_tag="TV191_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007894892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL1506950.1"
                     /translation="MSKTHQLVMVAILSAISFCLMFVGFSIIPGASFLKIDFSIIPIL
                     LGLVLMDLKQANLILAVRTLLRLALNNHGVNDLIGIPMNVIAVALFITAFALIWHRQK
                     GLVTYVLASLVGTGLLTLGMVVMNYVFAIPLYAKFAGFDIKAFIGTARYIFTMVIPFN
                     LLEGLIFAIVFYFVYIAGKPILERYPNSYHET"
     regulatory      complement(34893..35018)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
BASE COUNT        10494 a         8496 c         7080 g         9643 t
ORIGIN      
        1 accgacgata gttttattgc tgtttttgat cctaagctca aagaaattga taagcatatc
       61 tttgaggatt ctgtcattgc tagcgatttt tcagttgatg gagatgacat ttacctctta
      121 ggaacagatg tgaaaatcaa ggataactac ccaacctact tatatacgct atctatcaaa
      181 aatgggcaat tagctatgaa aaacaaagag ctgctctatg aacagcctga atccacttac
      241 tttttccatg atagcattgt caaagaaaag cagctctata ccgccttaag cggctatcga
      301 aacaatgtta ccaaggagag aaccgtttta gggcaggttt tccattatga tatgcagtca
      361 ggtcaaaaac attttttcga tctcactgag attgctccag tcaacatttt tgatttgggt
      421 cacgatacac tggcaataga gcatgagaaa aatgaagctg gaaaaattgg gtttagcctg
      481 tttcacctca atgataaaac gtctactttt attgacttat ctcaatttgg tttatccatt
      541 gaaagtgact acttaaaaga tgtcaaacaa attgacgaga acaccctatt aatattagct
      601 ggtcatacat taatcggata ccatatcaat gaccatcaag ctatctttaa caaacaagtg
      661 agtgatgatg cctttcatat atgggtaaaa tagctactca gttactgaaa acaacaaaag
      721 gtcaaagcac aagtccttga ctttttagtt aaaatagtta ggctagcttt ttctaagaag
      781 ctagcctaaa ttagtagtat ttggaactgc cattaagatg tgataaagcc agcatgcttg
      841 tgatgggtta tcagaatgtc acttcaatcc aaacgtcata aaagctcttt ttgaaaatgg
      901 tttagcacat gactgttgat ctaaagctag cagctgcaac agttgagtta gcttttttcg
      961 tgaggctccc aaagctatgt gtcgagcaac atcactaaca gctttaggag cttgatcttg
     1021 atgccccaca agctagcacc gtagggcact gctagcttgc taaagctttt tgctttcttt
     1081 tttcaatagc tgctctagct tttaacatat agttactgca attactctca ctatttgagc
     1141 tagaaccaaa acttcgtcac atcttacctt ggccaatctg gagaattaat accccagagc
     1201 tatttacatc ttattcagat ttttccaaaa gcttctttga atccagagct gggcaaagag
     1261 caaacagcta agaagaataa ggctcacagc aatgctcaca agaagaggct gctgactaat
     1321 ggtagcacac ataatcgcta aaacaatcaa aaagccacca acaattaagt cgccaaacat
     1381 cagcccaagc ataaaccatt ggctatttcc tctggtgaaa agctgggtga cgtcctgcca
     1441 tttcagatcc agcatgcggt aatcacgcct aaacatcaat tgcccttgta tgattcccat
     1501 caagacaaag cctaatgaaa aggataggac aataacgggg tgaaagccta atacaaacaa
     1561 tccaataaga gcataaacca ccaagggagc aaggatttgc agccctatca gcaagcgaaa
     1621 tttgttaagc aaaaagccct ttaagctaat gggtagggtc ttaataaagg tgaaattgtc
     1681 cttttcaaga gagatcccaa caccaacaaa gctggtcggc acagtacata tacttcccaa
     1741 gagcaccccc accaaaagcg caataccaaa gtactcatcg gtaatgtagc ttgaaaattg
     1801 tgcaccactt gtcacactag gagtgataaa gatcatcaca taaatcaaag gcatcagata
     1861 agtctgtgtc aatagtgtcg cattttgcag cgttgcaaga tggtgctttg tcaacaatcg
     1921 ctgtagactt tgctgacgat cagatgcagc cgccttgcgc gccactgctg catttttagc
     1981 ttttccacca acatagaggg tctctctgta ataagccggc atgatccgtc taacaagacc
     2041 atacagcatc agcatgacca aaagcaaggg aagccaaaaa ttaagcagag cctgactgga
     2101 aaacggtgcc acaacaacat catagctgcc cctaaaataa ggaatcaaag ggcgatctga
     2161 aaaggcttga tcagccatca ttcgctgatt gttagtcata ttgagaaata caatcaagcc
     2221 tagagcacca aaggtagaag caaacatcaa aaccgctgaa atcagcctgc gcttactact
     2281 cctcagaata atcctgccaa tccaagcatt gagatacaga gcaaaaacaa tcgagctgac
     2341 aaatagcacc acaaacagga taaacgctag cacaatcgcc aaagcatttc caatgatctg
     2401 ccagtaggca atcacgaaaa ggcttagcag cggcattaaa aatatggatc ccatacctaa
     2461 tgaggaaatc agcttagcaa tgaaaagctc ctcagatctt atcggcagat gaacatagag
     2521 cttaacgtca ttactctcat aaaagaccgc atacattgcc gtaaaggcat taacagttgc
     2581 cataacaaag aaaatagcaa tataaagtga caacagtccc ggatattggc taaaatcaac
     2641 acccataaac ataaagatgt aaatgactaa aaacagagca atcatcaagg cttgctgtct
     2701 gatcatactc ttgtaggcct tgaagttctc tttgggagcc ttttcttgct ttttctttaa
     2761 agctgtcagg gactgaggat tggaataaag gatattaatc ttgactaatt cccaaatagt
     2821 tgaccaattc ataccactat gcctcctgtg cttgacgtcc tgccaattca aggtaaatag
     2881 tctccagatc cttatcagga taatcagcct ttagctgctc aactgtccca acaaaaatca
     2941 atttcccctt tttcaaaatc ccaatccggt cacacagctg ctcagcaacc gacaagacat
     3001 gcgttgaaaa aagaaccgta ttaccagaag cagcatgctc tttcatcatt tcctttagat
     3061 caaatgaagc ctgaggatcc agtccagtca agggctcatc aaggatccag atactagggt
     3121 tggagatcaa agcaccaatc acaatgacct tttgacgcat accatgtgaa aagttatcaa
     3181 tcgtgttgtg catctcctgc gtcagctcaa ataactgcgt cagctcctca atccgagctt
     3241 tggtatccgc ctcactgacg ccataaatct tagcaagaaa ctgccaatat tcataggctg
     3301 tcaggtttaa gaaaatatcc ggtgaatcag gcacatagcc gatttgcctt ttaatggtgt
     3361 tacgatgctc actcagcagc tgaccattga ccaagacctc tctatagctt gcttcgataa
     3421 tagaggtcag gatactgatt gttgtcgtct tgccagcccc attgtgacca atgagaccaa
     3481 agatttcacc gtccttaatc gtgaggctta catcactcaa ggcctccttg tcaccgtata
     3541 gctttgaaac atgtctaaat tctatcataa ctctctccta tcctaaacca gacgctcgtg
     3601 ctggtcagcc tttttctaat aaataagcgt caagcgactg cttaaagcca cacaaggact
     3661 taggcaacaa caaatcattg gcctgtaagt aatcatcaag cgcttgattt agctgctctg
     3721 caatcgtcag cggattactg tttttgatta attggttaga agctgacagc aataatctgg
     3781 ctaaatggct attagcacga ttttctgggt aatcgtaggc ctgtttgatg acatcgtata
     3841 agcgctgctg ttccttttcc atagggcctc cctctaattt tgtacgttta cgctaataca
     3901 actagttaac acttcaatca taatctttat taggcttttt gtcaatatcc tatcgccata
     3961 tttgtctctt ttcacaaaag cagatatacc aacgatgatg gcgcttactt ttgttccttt
     4021 tttagggcaa tacgggcagt cagttgtgct tcttattttt agccataggt aacaaaatca
     4081 gacgataatc gttttcatta aaaaaaaaaa aaacgaaact acggagacaa actaatcagc
     4141 agctatttct tacatttagc tagcgtgtta agatagctat tggaaaagat ttttaggaat
     4201 acttcatatt tctatcatca aaggagagag aaatgataaa taaaagaaag aaaaaactta
     4261 tctacaggta tggtgtctgc tcggcagcag ttatcctagc agcgcttgct agcctaggaa
     4321 catgtaaaga agcaaaagca ttatctggtc cgccaggata cccacttact cgtgatttct
     4381 cccgtaactt cctagaagaa aatactgcaa aatatttaga tcaattaaga gaacatctac
     4441 agcacagatt tagtgaactt gagagcttaa caagaaaatt agagaaagaa ggcggtaccc
     4501 gaggtccagc agggcctccg gggccagccg gacctaaagg ggaacgtggc gaaccagggc
     4561 ctgttggacc tatgggacct agaggtgaac aaggtcctaa aggcttagac ggagcacgtg
     4621 ggcccgaggg acagcaagga aaacctggac ctgtcggacc tcaagggccg gcaggtccag
     4681 cggggcaaaa aggggaaacc ggacctcagg gacctcgtgg agataagggc gatactggag
     4741 aaactggaaa gcaaggacca gcaggagaac gtgggccagc tggacctcag ggaccgcgcg
     4801 gagacaaggg tgaaaacggt gcacccggtg agcaaggccc tattggtcca aaaggtgaga
     4861 ctggacctaa aggtgacaag ggagaacgcg gcgaaaaggg cgaccaaggt caacgtggtg
     4921 aaaagggcga ccaaggtcaa cgtggtgaaa agggcgacca aggtcaacgc ggtgaaaaag
     4981 gcgagcaagg ccaacgtggt gaaaagggcg agcaaggcca acgtggtgaa aagggcgagc
     5041 aagggccacg cggtgaaaaa ggcgagcaag ggccacgcgg tgaaaaaggc gaccaaggtc
     5101 aacgtggtga aaagggcgac caaggtcaac gcggtgaaaa aggcgagcaa ggccaacgtg
     5161 gtgaaaaggg cgagcaaggg ccacgcggtg aaaaaggcga gcaagggcca cgcggtgaaa
     5221 aaggcgagca aggtcaacgc ggcgaaaaag gcgaccaagg tcagcgcggt gaaaaaggcg
     5281 accaaggtca acgtggcgaa aaaggcgacc aaggtcaacg cggtgaaaaa ggcgaccaag
     5341 gtcaacgtgg cgaaaaaggc gagcaaggtc aacgcggtga aaatggtgag caacagccaa
     5401 agggtgacca aggaaaggat accaagccat cagttccaaa ggcaccagaa tcaccaaaaa
     5461 tgccagagaa gccacaggct cctgaaaagg ctcctgcacc gaaagctcca aaggcttcag
     5521 agcagtcagc tagccctaag gcaccagcac ctcagtcaac accaagcaaa aaagcagtcc
     5581 taccagctac aggagaggca agccatccat tctttagtct ggcagctctt agcgtcatcg
     5641 ctagcgcagg tctgctaacc ctaaaaagaa agaaaagcta agccagctat ttgacaatag
     5701 cttctagcaa ctcgggatag atctgcaagg ctgagcagta gcactattaa atctgaaaca
     5761 aaaacgcatg acgtcctccc taaaaagggt tgaacatcat gcgttttttt gtctaataat
     5821 gccgaaagca agcctagata aggcctgctc cagcttaatc acttatgata aggatttgta
     5881 caattcagta gcatgctcta ctgtaaagcc atattcttca aagatacgat tgcccggtgc
     5941 agaagctccc catgtatcaa tggtcagtgt tttccctgca aggccaacgt attttgccca
     6001 gccaaagctt gagcctgctt caatagctag acgttttgtc actgctgctg gtaggatttc
     6061 ctccttgtag gaagctggct gctcatcaaa gatattttgt gatggcattg ataccacacg
     6121 cacatggata ccatctgctg caagagcggc ttgagtatcc attgctagct tgacttcaga
     6181 gccggttgca atgataatcc catcaaggtc accctttgcc tctgacagga tataagctcc
     6241 cttattaagg ccatcttctg ccaattcctt agtaccttca agtacaggaa ggttttgacg
     6301 tgttaagaca agcattgtcg gacggtctgt ctcagcgatc gcacgcttcc aagcagcgtt
     6361 tgtttcattg ccgtcagctg gacgaataac gttcagattt ggcattgatc gaacactagc
     6421 tagctgctcg attggctcat gggtcggacc atcttcacca accgcgatag aatcatgcgt
     6481 catgacataa accgttggta gctgctgcaa ggctgccata cgaaccgctg gcaataggta
     6541 gtttgaaaag acaaagaagg ttccgccata aacacgtgtt ccaccatgaa gggcaatacc
     6601 gttcatcgct gctgccattg caaattcgcg tacgccaaac cagatgttac gaccagcata
     6661 atgacccggc tggaagtctg tctcagcctt aaccatggta ttgttagagg cagaaaggtc
     6721 agctgagcct ccccagaagg ctggcacctg ctcagagatt tgttggatag cctgctggct
     6781 agaaacacga ctggctactg ctgtgccaag ctcgtgagct tgcaactcaa cctctgccgc
     6841 ctcattagca aaggcttttt tgtattcggc tgctaactca gggtatgctg cttcataagc
     6901 tgcaaatagg tcattccatg cctgctcagc ctgctcacca cgcgcctgaa ggccttgtct
     6961 aaagcgctca gtcacctctt gcggcacctc aaaatcagca tgggtccatt gataagattt
     7021 cttagcaaag gcaatgcctt ctgcaccaag cggagcccca tgaacagctg aagttccttg
     7081 cttttcagca ccaaagccaa tgattgtctt tacttcaata atggttggct tttcagtctc
     7141 tgccttagct tcctcgatag ctttagcaat ggcctctagg tcgttgccgt ctttaacaag
     7201 gatatgctgc cagccgtaag cttcaaaacg ccccttgacg tcttctgtga aggccattga
     7261 ggttgggcca tcaagcgaaa tatcgtttga atcatatagc aagacaagct taccaagctt
     7321 caagtgacct gccagactgg ctgcctcctg actgacaccc tccataaggt ctccgtcacc
     7381 atttagagca taggtatagt ggtctacaat atcaaagcca ggtctattga acttagctgc
     7441 taagtgtgcc tctgccatag ccataccaac tgcattggca actccttgtc ctaaaggccc
     7501 tgtggttgcc tcaacgccat ctgtatgatt gacctctggg tgacctggtg ttttagagcc
     7561 ccattgacgg aagttcttaa gatcctcaat agacacatca tagcctgcta ggtgcaacag
     7621 gctgtaaagc atggcactac catgacctgc tgataggata aagcggtctc tatttgacca
     7681 acggcggctt gtctttggat tgactgtcat aacatgattc catagcacat aagccatcgg
     7741 cgccgccccc atcggcaaac ctggatgccc agaatttgct gcttgaatag cgtccattga
     7801 tagagtacga acagtattaa ctgccagctg atcaattgca tcaaatgtca taagtaaaac
     7861 ctctctgtgt attacaacta aaaattaaac gttttccatt gtctattgta acataaaagt
     7921 aaactgattt ttaacaaaat cctataaagt ccttaaattc ttatctagca ataagcattg
     7981 ctgttcctag ctttttgtga ttgacagctg tcttagatag agcacctatg ctcataagaa
     8041 aaagcaagcc tagctgttgc cagctaagca agcattcctc tttggtacct ccctttggct
     8101 acagtaagcg ccagctgcct gttaattcta gcgcaacagc aaagcaccag ctgatcctgc
     8161 cacctacaaa tagctaatcc caaactaacc gctacagcca cattagaata taaggagagc
     8221 tctatgctct tagcctattt tttaaaggaa gcccaatcct ccataaaggt ctttaagcca
     8281 tttgttgtca atgggtgctc agtcatcttc gcaaataatg gatctggaat ggttgcaatg
     8341 tgtgccccta gctgtgcaac agcttcaaca tgggcagctg tccgaatgct ggctgcgatg
     8401 atttctgctt ggaagccata caaatcaatg atcccacgca aatcactaat aagctgataa
     8461 ggatctgctc caatatcctc taagcgacca ataaatggac tgatataggt cgcaccagcc
     8521 ttcatggcca ttagtccctg actaactgta aaaataagcg tcacatttgt tttgatgcct
     8581 tcttgtgaca agacattagt tgcttttaag ccctctgtcg tcatcggaat tttcacgacc
     8641 acattgtcat gccacttggc aatgttccta gcctctgcaa tcatttcctc tgcggttagt
     8701 ccggtgacct ctgcactgat agggccgtcc acaatctcac agatttcctt gataactgtc
     8761 tcaaaatcac gaccctcacg cgagataatg ctagggtttg tggtaacacc gtccacaaca
     8821 ccaagctcat taatcgcacg aattgcctct acatttgctg tgtctaagaa aaatttcatc
     8881 ttaacctccg ttaattagtc tgttatcagt cattgaacag catgacgctg tttaccgtct
     8941 acattatcat tataaaagtc actcttagga tataaaagac caagtatcac acagtctagt
     9001 gttcaaaact agacctagct atgggactct gtttctttaa aaggcttgat tcttacagct
     9061 cctctgcaaa aaactgtgtg gctttgacag ctcttttcca gccttgatat aacttttctc
     9121 ggcgagactc actcatgctt gctttaaaca gctgacctgt agcatttaat tgctttagtg
     9181 tctccatgtc cttccagtag cctacagcaa gcccggctaa aaaggctgct cctagagctg
     9241 tggtttcaag attttcagca cgagcaatat caatccctaa aatatctgcc tgaaactgca
     9301 tgagcatgtt attcatagcc gctccgccat caacacgtaa ttgctggata gtgatccctg
     9361 agtccacctg catggtatca atcacatctc tgacctgata agcaatagac tgtagggtag
     9421 ccttaacaaa atcctctttt gttgttccac gcgttaagcc aaatactgag ccgcgtgcat
     9481 tggaatccca ataaggagcg ccaagacctg taaaggctgg tacaacatat acctcatcag
     9541 cattggttga agccaaggct agctgttcag actcaaaaga ggtttttatc attcgcaagc
     9601 catctcgtag ccattgcaca gcagagccag caataaagat agacccttct aaggcataat
     9661 aaaccttgcc attaatacca tatccaatcg ttgttagcag gttgctgctg gataattgag
     9721 cctcttgacc agtattcatg atgataaaag agcctgtgcc ataggtattt tttaccatac
     9781 caggctcaaa ggccagttgc ccaaataggg ctgcctgctg atcacctgcc atgccagcaa
     9841 tagctacctc tcctccgtaa aaatgaaaag aagccgtttt accataaatt tccgaattag
     9901 acctgacctc aggaagcatg gccttaggga tattcagcaa ggccaatatc tcatcgtccc
     9961 attttagctc tttgatattg tatagcatgg tacgtgctgc attagaataa tccgtcacat
    10021 gtaccgcccc gtccgttagc ttccaaacca gccaggtgtc aatcgtgcca aataataatt
    10081 ctcccctttc agctcgctct tgagcccccg gaacatgatc aagaagccat ctgagcttgg
    10141 tcgcagaaaa ataagcatct ataaccaagc ctgttttttc atggatcatt ttggtatagc
    10201 catcacgctt tagctgctct gcaatggagg ctgtttgtct agattgccac acaatagcat
    10261 tatagatggg cagacctgtc tgtttgtccc agactaccgt tgtttcacgc tggttggtaa
    10321 tgcctatagc ttctatttgc tctggcttta taccagactc gataaaggcg tctgcaataa
    10381 cagactgcac caaattccaa atgtgattgg cgttgtgctc aacccagcca gcctgtggaa
    10441 aaagctgtgg aaattccttt tgactactaa ccagcgcttc tcctttctta ttgaaaataa
    10501 tggcacgaga gctcgttgtg ccctgatcaa tagccataat ataggtttca gttcccatgt
    10561 gtcctccatt ctatcgctgc tgagataggc tctctcaatc atagcaagcg ctttctactc
    10621 tattatacaa catttacagc ccatagccta tccttctagt cataaaagta tcactctgcc
    10681 aaatcctaag ctgataatgc ctatcatttc aactaaacag cccttatcac agccaaatac
    10741 cagcaacaaa ggcgggctat aggctagcgc ctaaatggct gccaacaagc tccagctcta
    10801 tcaggcacaa caaggaacaa caaaaaacct aagccctttt agcatataaa ggcttaggaa
    10861 tgttacaggc ttttatcaca taagcggtga tagcttttta atcgtaaaca ggctcagagg
    10921 acttttctaa aatatctcca ctattagcat caatagtata gctgtactcc tgatccttgg
    10981 cgtcaaactc aatatcgtag accaccctac cgtcgtctgt ttctttcgtc agctttagcc
    11041 tttgggcgtc agctgctgtg attgaggcgt ccttaaaagc aagctccttg gccttgtcct
    11101 ctgaaatgcc agctgcttga tcagcctgac caccagctgc ttgagctgaa gcaggagcct
    11161 cagtgattgg ctcagaggat ttttctagga tctcaccggt attagcgtca atggtatagc
    11221 tatactcctg atccttagca tcaaactcaa tatcatagac cactctacca tcgtctgttt
    11281 ctttcgtcag cttgagcctt tgagcgtcag ctgctgtgat tgaggcgtcc ttaaaggcaa
    11341 gttccttggc cttgtcctct gaaacacttg ccttcctatg attctgagca ctgccatttt
    11401 gacctagagc ctgattctgt tgacgacaag ctgataggct gattaaggat agactcgtaa
    11461 gagctattac tgaaagtttt ttgattatca ttgtattgac cttccgtctt tattcatctt
    11521 atttcctcta gtatacatta aataatctga ttttacaatt ttaaagcgct aaaactctct
    11581 taaccaggct tactccctta tatgataacc cccaaagagc ccataaggta aaggtaagga
    11641 ctttgctatc cctcaaccaa gaatagatca cccagccgaa taaaaaaagc aattattggt
    11701 agaatgagaa gaattatttt ggtcttattt attgccttca ccagctatca atcactattt
    11761 aatgaccatt ttggtatgaa ccctcactgc cactcactat ctgacaccaa gctactttta
    11821 agtaccagca tcgatgtttc ttacacctcc agtgcgtatc catagccgac cttcagcatt
    11881 taccagcatt tctgattgat tacaaatact ccctaaactg ttgaaaaagt atctaaacga
    11941 accatacaaa acttaattta ccttttttct atataaatag ctaaaaaaca tagtaaggtc
    12001 acaagggata taagatttac attgcttata gtagtcgata agaaataaaa aattaaaaaa
    12061 ataaagtaag aagccccttc tttgcccctc ttagcactgt caaccagtat atagataaaa
    12121 attaaagcat aaagacctga aaaagtaatc aataacatct aatttacctt atatgccaag
    12181 catgctccta aagcagtaaa gccgtctata catactcctt ttagcaccgg atgaggtatt
    12241 ttgcaaaatg taattcctgt cttgagacct cctaatcccc cgataacagc attacctgct
    12301 gcatttcctc ctgaaatatc ttgcatttca cttattgcta atgctctata atgttccatt
    12361 tctattatcc tcctaaaaca aggttccaaa ctcagaatct ttctgttttt ctcatttcta
    12421 aaagcctcct gtgacaccaa tagatccaca agctactcca catactggaa atccaagtgc
    12481 tgcgcctgca cttcctgctc caatcacacc tgacacattg gcagcccaat tattttttcc
    12541 tccttcaaag ctagcaagca tttctgtagc cattacgtca aattattgta ttgattgcaa
    12601 atactcccta aaaatcgatg ttgtccagtt gcaaccttga catatttagt ataacgcttt
    12661 ttttgtaaaa cattcctcca tatcctaaac agtcgttgaa acgtcctaaa tgggagcatt
    12721 tttttcgttt aagactgcaa agtgaccatt aagggaaggc gtgaagcgac aagcctgtgg
    12781 ctttaggaac cttaaaaaca ttaaaagcaa gcttctcatt gctattaaca acacaaaaaa
    12841 agcaccagtc tggtcctcac taggtactag ttatcagtca cccccctaaa gttgacaaga
    12901 agccaaaaaa agagaactga ctagctctct tagtgtgcag acaaatctat ctgcttacat
    12961 taatgacaat tctcagaagt gcaaaagaca gctattagcc cttacttgag tacctctcct
    13021 ttgcttggcc tactagagat tctctcaatc aggcgactag tccggattaa aagccagtct
    13081 agccaagccc atgaaattgc tgatagagct cttggcgatt caccttatag tctttggcga
    13141 ttgtcttgat cgcctgatta ggcttcatgc cagcagcaat agcctgttga acaagtgcta
    13201 gcagatccaa atcctcagca ggctctgatg cgtcagcttg attggcacct gccacaatca
    13261 atagacactc acccttgagt ggatggtctg ctagataggt caagacctct gaaatctgac
    13321 cacgctggta ttcctcaaaa agcttggtta actctctcac cagcaccacc tggcgatccc
    13381 catagcaggc cagcaggttt gttagcgtat ccttaacacg ataaggagat tcataaaaga
    13441 tttgagtctc tggataatct gccttagtca tcaaaaatgc cctttgctgc ccagcttttc
    13501 ttggcaaaaa gccataaaac agatggggct ggggcgccaa gccactagca atgaggccgg
    13561 taatgcccgc agaagcaccc ggcaaagcaa caacagtaat atctcgatca atagctgctc
    13621 tgactagctc atgaccagga tctgaaatag agggcatacc agcatcggag acctgagcca
    13681 atgaccttcc agccaacaac aggtccagca aatctggaat tttatcataa gcattatgct
    13741 catgaaagct tacctgcttt gtctttatcc caaaatgctt gagcaacaga ccagtatttc
    13801 tcgtatcctc tgcacagata atatccacct cttttagaac attgaccgct ctaaaggtca
    13861 tatcctctag gttaccaata ggggtaggca ccagatagag aacccctgac tctttttctt
    13921 ccttgaagct cttttggatt tgcatgactc tactttctat ctaatagctc tcgacaaaac
    13981 atacactctt catcattttc acgacgttgc ccatagaaaa aattgcagat atgaaagccc
    14041 tcatcataaa tgccctccaa gtggtccttg ccctgcttag aagaggtctt ggccagattt
    14101 tcgtgctcca attgactcaa gcgctcacgt aatttggtgt tttcaagcct aaggatagta
    14161 ttttcctcta cgagtccttg gacctgcttt ttcattgctt caatttcagc taaagtcacc
    14221 atcaggtttt gtgaaaagcc atcaaaagcg tcaaacagtt cttttttatt cactaacttt
    14281 aacctcctct aaagcatagg ttaccaaggc cagctggtcc ttaaagcgaa cctgaatggt
    14341 atctgtaaaa agatcaattc ctgcaacctc acctggtccc tgcgctgttc ttactatagt
    14401 accataatca ggaaattttt tcttactttc ttgataaaaa tcgtcctcat attgtaggca
    14461 gcacagcaag cgaccgcagc agcccaaaga ctttgccgaa tgcaaggaca gcccttgatg
    14521 ttttagcatt ttgattgaga ctggaggaaa ctctcctaaa aagcttgaac agcatagtgg
    14581 gcgaccacag ggacccagcc ctccataaac ccttgcctcc tcacgactat taatctgacg
    14641 cagctcaatc cttgtcttga aataggcagc caaatccttg aggagctggc gaaaatcaac
    14701 acgctcctga gcggtaaagg taatcaaaac ataacgtctc tcaagggaga aaacaatgtc
    14761 aaccaaggtc atgtctaagc catttctgtc aatcatctct gctacttttt gctttgactg
    14821 ggctgctagc tgaaggtttt gctggtaagc cttgtagtcc atgtcattgg caggtctcaa
    14881 aacagagggc atatcctttg gcaggtcgtc cttacaaaag ctttttatcg gagaattgac
    14941 cactgccaat cgactgccct tgccatcaga tatgacaagc ttggtttgca caggaaaggc
    15001 ctgatcggtt tgaacgtacc tgacagagca ggtgtcacaa tatttaattc caatcgtact
    15061 tatcatgaaa tcaccatata ttctaacgta ttttgaaagc tgacattgct ttgccacata
    15121 agtctagcct gataaacagc ctccagatag gtaaaagcat tttgtcgact gtagtccttc
    15181 gccaagatta aggttaaaag agttagtgcc atgtcctgct cctctttttc ctctgctagc
    15241 tgaaccaagc gattaagctc cagataagcc tgttccttat cctgaaacca gatggaaaca
    15301 aaacgctcag cctgcgccat cagctccaac agcctggtgt tttcagaaaa agcggtaagc
    15361 tgctgggcat tggctgctaa tctggctaag aggtctgctt gatgtttcaa aagccccttt
    15421 ttttgggcca gctcagagag gtagtgctca tcttttggaa agtgaaaaac ctgtgtacgg
    15481 ctcttgatcg ttggtaggac ctgattgtca tcattcgtta gtaaaaacat atagcaatcc
    15541 ccttgtggct cttctatata ttttaaaatg ctgttagctg cattgacatg catcttatca
    15601 caatccttaa tgataaaaac ctgccgcctg ccctcatagc cggtctgcga aaaatttgtc
    15661 atcatttctt tgacggtatc agtcttgata agctgaccga caggctctaa gatggtgaca
    15721 tctgaaaagt cattgtgctc aatcagctgg caagcacgac agtgatgaca aggagcattg
    15781 cctctttttt gttcgcaaaa aagagtcttg gctaaaaaaa gagccatgtc aaaattggca
    15841 aaatcacctg aaaagaggta ggcatgattt agacgttttt tttgcaaaat ctcttgaaag
    15901 gcctgataga ccctaggagc cttttgagcc aaatccattc ctaacctcct gctatgcttg
    15961 actgtgtgtg ataatggcag ctaaagccgc tgacacaacg ctttctaagt cctgtgatgc
    16021 atcaatcttg acaatacgct ggggattttc caaagccagc tccagatagc ccttacgaac
    16081 acgctggtgc aaatctaatt gctcaagatc aagacgattg atctctcgct cagtattttg
    16141 tgcaatcctt gccaatccaa gctctgaggg cacatcaaaa tacagggtta aatcagggtc
    16201 aacaccatct gttgcaaaat gattgagcca ttgaatggct tgcttatcca gccctcttcc
    16261 ggcgccttga taagcaactg aactgtcaat aaaacgatcc accaaaacca agtgtcctga
    16321 ctcaagagct ggcatgatct tttcaaccaa atgctgcctt cttgctgcaa tatagagcag
    16381 cagctctgtt ttatcgtcca tggtcgtgtg actgacatct aagatcagct gacgaatctt
    16441 ctcagcaatc gcaacgcctc caggctctct cgttgttaca atggtttgtc ctagagctgc
    16501 ctgtaagagt ggcaccagtc tttccagcac cgttgttttt cctgctccgt ctggaccttc
    16561 aaacgttatt aattttcctc tagtcatctt tattcctttg tttatcgtta cctctatttt
    16621 accaaaattt gcctgaaaaa gcactgccaa ttcattgggc agtgccagat cagaaaaaag
    16681 cctttttgtg ctgcctttta ggcgatagga ataaaaagcc agccctcaaa gcagcagcct
    16741 aagacttgtg cctcacacct caaagcctat gagcagccac tcgataaatg acaatcgtct
    16801 cagctcttat tttctttgcc taagcaagcc agcagggctg atccatcagc tttgagcaat
    16861 tgatgagcta agacatgcta tataagacag gatcaggcct acttagccct gctcaggtag
    16921 ggcttgaggc tctagaggct cacgatgtaa attcccaaca aaatcacaat caatgtcatc
    16981 aaaggctgat accttcacct ctttgacaaa tgttagccga ctaatgtcct ttagcttttc
    17041 ttccatgtcc tctttattga tgtaaataac aaggtatcga gaacgcctgg aatggtagta
    17101 caagtcacca tatttcatca cttttctagc gtctcgattg taatacaggt agataaccag
    17161 cccaattctc tgctgttttt gaaacattta ggtactcttt tcttttatat tttgatacgg
    17221 tccaagctca tgtcgaggtc tatttgtcgc caagggaagt cctgtgtcga caagaatatc
    17281 ctcagacact gcttctgcaa tagctgtcga aatcgtcgcc aaaacctcct gcaaatcaac
    17341 ctgtgccaag cgcagatcag caaccaatgg atgcaggtca agctggcgct tttgatgaag
    17401 taattggcag cgcaacgctc tagcatctgg acacaactta agcaagtcct gcctaagctc
    17461 ataatcctgc ttaagctcct caaataaggc taactcggtc tgtagggcca aatctgcctc
    17521 aaaagccttt ttagccaagg cataggcctg atactggctg cttgtcctaa tatcctgaac
    17581 cagctgctca atagcctttt caatggcaaa caattcttca tttatgatta gcataggtta
    17641 attataccat aattttaagg aagatagccc tctttagcat gcaaaaagcc cctgaaacaa
    17701 tttgtttcag aagctgttaa gctattttac taagctctct aagctagctc attattttcc
    17761 atgatttcat caataaagcc ataggctagg gtttcttctg cgctcatcca ataatcacgc
    17821 tcagcgtcct tatggatttg tttgatcgtt ttaccggcat tttgtgccaa aatcttttcc
    17881 aggcggtgac gtgtctttaa taaatgctca gcagcaatgg ccatatccgt ctgctgcgta
    17941 ccacctcctg tgcctcccat aggctggtga atcatatatt ctgcatttgg aagcataaag
    18001 cgcttgccct ttgcacctga tgaagcaata acggttccca tagaagcagc catacccata
    18061 acaatggttt gcacatctgc cttaataaag ttcatcgtat caacaatagc taaaccagct
    18121 gatacagagc ctcctggggt attcacatag aggtaaatat cttttgtgtt gtcttgggca
    18181 tctaaaaaca agagctgcgc aataacagag tttgccatat tatcctctac tggaccagtc
    18241 agcatgataa tacggtcctt taacagacgt gaataaatgt cataagaacg ctctccacga
    18301 ctggtttgtt caataactac aggaatcata aaaatctcca atctatcgtg actgtctaac
    18361 accactctgc ctcatgcagt gacaggcagt caaacacatc tttttataat gattgacctt
    18421 attataatct cttggtcaaa aaaggtcaaa tgataaactt gcttttaaaa accttccagc
    18481 ctaaactaga aagtcttatt agctttagca ggctagcctc tagcaagcag agcctagcac
    18541 aaccaaagcc tgtagccttt tacttggtac caaataagcg atcaccagca tctccaagac
    18601 caggaacaat gtagccatga tcatttaatc tttcatcaag ggctgcggta taaatgtcaa
    18661 catctgggtg agcctcctga agctttttaa ccccttctgg tgctgctacc agacacacaa
    18721 acttaatatt agcagcccca cgctttttca gtgaatccac tgcaagaata gcagagccgc
    18781 cagtagccag catcggatca acaataaaaa tttggcgctg atcaatatcc tctggcagct
    18841 tcaccaaata ttcaaccggc tccaaggtct cctcgttacg atacataccg atgtgaccaa
    18901 ccttggcagc tggcacaaga ctaagaaagc catccaccat accaatacca gctctaagaa
    18961 tcggaacaat tgctaatttt ttacctgcta actgcttttg aaccgtcttg gcaaccggtg
    19021 tttgaatctc aacatcctct aatggcaagt cacgagaaac ctcgtagccc ataagcattg
    19081 caatttcatt gaccagctct ctaaaatcct tggttgaggt atcctgacga cgcaggattg
    19141 atagcttatg ctgaataagt ggatgcgaaa taacctgaca ttttcccatg atgacgtact
    19201 tccttcttta ttttttacac ttttgctatt ataccaaaaa attgaaaacc ttgcttactt
    19261 ttttcagatc cggttgaaat gataaaagca agaatctgat cagctagctg cctgcttcag
    19321 ctgccttgat cttgggtgtc aaagtcccaa tttttggcga tacctagctg ctctgctgcc
    19381 aattaatttg tccagctgac gcgtcaataa cgtcatgtag gcgtaaacac ccattcccaa
    19441 gccaccaata atcactaagt aaagcaggct agtcaatctg cctgtcggct taaacaaata
    19501 gcccaaaaac cagttagcta gtagcacaat caggcccatc aatgctgtct caatcaccgt
    19561 tagtaatata cgcttatgca gcagcttacg gttaaatcgt gtgacctgat gtagacgacg
    19621 gtacatgaga tagataggca ctagcaagcc aagggtcgta gctaacaaag gaccataagc
    19681 atgaaacaga tagatcaaag gaacctgcaa aaccagcttg acaaaaacac cataagcaaa
    19741 ataatagatg gccttacggt tttcaaacag ggcctgcagc atcggagaaa aaagcgtata
    19801 caaggccatc aatagggtaa ggcaaagcac agcaacaaac agcctaacag cctgtccctc
    19861 gctactaccg taaaaaaccg tataaagagg ccttgccagt ataatagctc ctgtcagagc
    19921 aggcaataaa aacatcagca gcatttcaat gttgttaatg atcaggcgcc ctgctgctcg
    19981 catgtccttt ttaatgtaat tttctgtcaa taaggcaata ccaacactac caattgaagc
    20041 ggctactgca atgagcacca tggtgatttt agcagggttg gcgttaaaat acccaaacag
    20101 cacccagagc tgagaacgcg tgtagctggt aaacagagtc atcgtattga caaaggtcca
    20161 ctgatcaagg agctgaaagg cctgaatcgc acttcctgta ataataaagg gaatcgactc
    20221 ctttaacgtt tcaataagca agcccttgat gtcaatagga atcgcatgct ctgtcttggt
    20281 aaaaatagcc tttaaaaggc cctgcgtcca gaaataataa aagagcaccg ccatactggc
    20341 tatcattcca ataaaagcag caaaggtgga ctgcgtaaca gctgcaatat agtccttaga
    20401 ccccattttc atgatgaaaa aggttgttag aagcatccag atcacacgaa ccagctgctc
    20461 agcaatttgg ctaagagcat agggcttaat ctccttatag ccctgaaaaa tccccctaat
    20521 cacgctcatc actggaaaaa caaaaacagc taatgataag ctatgcataa tcgggacaag
    20581 ggtctcatca ccaccggaca agcgagcaaa gagcggagat cccagataca tcagcactga
    20641 gaaaatcaag cctaatacca gcataacctt tagagtgctt cgaatgagct gatagctatg
    20701 ctcttgctgt cccatcgagt tgtacttagc gacctgctta gcaatggcaa catttagccc
    20761 tgttgtcgaa atcaacaaaa aataggcata cacattgtat cccatattaa agagcgcatt
    20821 tgcctgtatc gcatactgcc ccatccatat gtaccatgga ataatatata gaacgcctaa
    20881 aagtcggcta ataaaattac ctgcggtgga ccaggctgct ccctgaacca tcagctgttc
    20941 ttgtgtcaat tgtttttttt ctgtcgacat atccgttctt cctagttttt atagctttat
    21001 tataaacttt tgcttgtgac ttgtaaaaca agaacattaa ggataaaata aggctatgat
    21061 aacaattgag cacttattaa ccattttaaa aaaggaccat aatttccgag aggttcttga
    21121 tcaagacggc taccacttta actatagcgg tctacagttt gacagcctta gctacgacag
    21181 cagacaagca gatgagcaga cgctcttttt tgctaaggga tcagctttta aggctgactt
    21241 tttgagacag gccattgcca agggactaag actctatgtt tcagagattg actatcaggt
    21301 agggatccct gttattcttg ttaacaatat taagcacgct atgagcctag ctgcgatggc
    21361 cttttatgat tacccacaaa ataagctcaa gctattagcc ttcaccggaa caaagggcaa
    21421 gacaactgct gcctactttg cctatcatat gctaaaggaa tctcataagc ctgccctgct
    21481 ctctacaatg aacacgacct tagatggcca acactttttt aaatcgcagt taaccacacc
    21541 tgaaagtctt gatttatttg cgatgatggc tcagtgtgtg gctaatggca tgacgcattt
    21601 ggtgatggag gtctctagtc aagcctactt ggtcgggcgt atctacggct taacctttga
    21661 tgtcggtgtc tttcttaata ttagccccga tcacatcgga ccaatcgagc acccaagctt
    21721 tgaggattat ttttaccata agcggctctt aatggaaaat agccgagctg ttgtggtcaa
    21781 tagcggtatg gagcatttta atatcctagc agagcaggtg gctgataagc ctcatgattt
    21841 ttatggcaaa ggggcttgca ataggctgct gcagcggcag gccttctcat ttcaagcagc
    21901 cggcaaggta gctggagact atgcgattca attaattggc agcttcaatc aagaaaatgc
    21961 tatggctgct ggactagcct gtcttcgact gggggcaagc ctagaggata tccgccaagg
    22021 cattgctaag acaaacgtcc ctggccgcat ggaggtctta accatgacca atcaggccaa
    22081 ggtatttgtt gattatgcac ataacggtga tagccttgaa aagctcctat ctgttgtcga
    22141 agagtaccag aaaggccaga tttacttgat tctaggagca ccgggcaata aaggcgagag
    22201 ccgtcgggct gattttgggc aagtcatcaa ccagcacccc aatgttcgta ttattctgac
    22261 tgctgatgat cctaattttg aggacccaca gctgatttca gaggagattg ctagctatat
    22321 tcaccgcgag gttgatatta tcattgaccg taaagaagca atcaagactg gtatggagcg
    22381 ctgtcagaat gagcaggatg cactcattat tgctggcaag ggggctgatg cttatcagat
    22441 tgtcaaggga caaaagactg cctatgcagg tgatttagcg attgcaaaga gctacctata
    22501 gactggtcta acaggctaaa cagtaataat tcttaagatt actgataatg attctaagct
    22561 ggctcctttt ttagcataaa ctcagtaatt agattctgaa aggctttttt aggccttttt
    22621 tctatgctat aatgggatag cttttaagag aaagcgcact attatagtca gaccaaaaaa
    22681 gcgactagca tttcataggc tatcagcccc ttagaatttt gctagctggc tttgcttgac
    22741 tattagaaag gagaaaaacc atgtcaacaa tcagtgctga gaggatttca gctggctatg
    22801 atcaatcgct tatcatcagc aacttatctg tcactattcc cgaaggaaag gtaacaacca
    22861 tcatcggtgc taatggctgt gggaagtcaa cccttttaaa gactctggca cgactattgc
    22921 cactcaaagc agggcaggtt ctcttagatg gacaagccat tgctagacta gcaaccaagg
    22981 acgttgccag aacactagca gttttacctc agctgcaaga agctactaca gctactgtct
    23041 atgagctggt ttcttatggg cgttatcccc accaatccta cctaggacaa ctcagtcaag
    23101 ctgataagga taagatttgc tgggcaatgg aggtcacaag catggcaccc tatgctcatc
    23161 aggctgttga tgccctgtca ggcggccaac gtcaaagggc ctggattgct atggccttag
    23221 cacaggatac tgatattatt tttctagatg agccaacaac ctacttagat atgaatcatc
    23281 agctcgatat tttagaatta ctaaaggagc tcaatcaggt ctctggaaaa acaatcgtga
    23341 tggtccttca tgatttaaat ctttcagcac gctactcgga tcatctgatc gccatgaaaa
    23401 atggacatat caaatattct ggagaggtca accaggtgat gacgccagag atgattcaag
    23461 acatttttca agtaaaggct cagctcgtca ctgatcctct ctatcattgc cctacattgc
    23521 tgacctatca gctgatataa atttattcta ggagaataga atacatgaaa aaactactgc
    23581 ttattttaac tgtttttgtg acagctttta cattagtcgc ctgctcaagt caaagcaagc
    23641 aacaagaaag caccagcaaa gcaagcctat cccacaagcc aaaaattgct ggagtgacct
    23701 attatggtga cattcctgtc aagccaaagc gcgtggttag cttagcagct acatatactg
    23761 gttacttggc aaaattagac cttcatctgg tcggtgtcac ctcctacgac aaaaagaacc
    23821 ctgttttaac aaaaagcatt actcaagcca agcaggtggc agctactgac ctagaggcta
    23881 ttacagcact agagcctgat ctcattgttg ttggctcaac agaagaaaac attgaccagc
    23941 tagcaaaaat cgcaccacta atctccattg aataccgcaa gcgtgattat ttgcaggtgt
    24001 tttctgattt tggccgtatt tttaacaagg aaaaggaaac tgaccaatgg ttggccgact
    24061 ggaaacaaaa aacaagtgac tatgaaaaag aaataaaaca agtcaccgga tcagctgcta
    24121 cctttacaat catggggctc tatgaaaagg aaatttacct ttttggtaag gactggggaa
    24181 gaggtggtga aattattcat caggccttac attatgatgc tcccgaaaag gtgaaaaaag
    24241 aggtgtttaa gcagggctat ctgtccttat cacaggaggt tctaccagat tatattggtg
    24301 attatgtgat tgttgctgct gaggatgacc aaaccggctc agccttatat gagagcgacc
    24361 tttggcagca gatccctgct gtgaccaaca atcatgtcat caaggtcaac gctaatgtct
    24421 tttacttcac agacccactg tcactggagc accagcttga ggttctaaaa aaggctatcc
    24481 tctcaactgg tgcaagtcaa taaaaactta agatgacagc tcaacatcat actaagccta
    24541 aactagctaa agcagctcct ccttggctga tcttaacctt tatcagctta actctagtgc
    24601 ttgccattta ctgcagtctg aggtttgggg ctgtgtcact atcacatcag gagctctatc
    24661 atattctact tggaaagcag gaccagggtc aaaaggccag cattattttg gacattcgcc
    24721 tgccccgctt gattttagca gctctagttg gtgctgcact tgctgtttca ggagctatca
    24781 tgcaaggcat taccagaaat cccattgccg agcctggctt actgggaatc aactctggag
    24841 ctgggctggc attagtcatc ggctatgctt tttcccctca tcttcattat tcgacaatta
    24901 tattactttc cttgctaggg tcactcttag cgaccctatt aattctcagc ctagcctatc
    24961 aagctggtaa gggctacact caaatgaggc ttattttagc aggagcgatg atatctatgc
    25021 tactgtcagc tatcggacaa ggaataacaa cttattgtca cctagccaat gccattattg
    25081 gctggcaggc gggaggattg atcggggtca attggcagat ggttagctat gttgcgccac
    25141 tcatcatctg tggcttagcc ctatcttatc tgctagccta tcatttgacc attttaagct
    25201 taagtcaaga gcaggccaag gccctagggc aacgcacctt cttgattagc cttatcttta
    25261 ttggacttgt gctgcttctg tcttctgctg ctgtagcagt agccggcagc atttcctttg
    25321 tcggcttgat tatccctcat gccatcacat tagtcactgc taaggattac cgctggatcc
    25381 tgccgctagc tactcttctt ggagccagct ttatgctttg ggtagacttt gcctgtcgga
    25441 atatcaatcc cccctatgaa acaccgctat ctgctttgat cagctttatt gggctgccct
    25501 gctttttatg gctagttaga aaaggaggtc gcttttgaca gctactaaaa gacacgtccc
    25561 attatttcta ggactaatct ctggactggt ctgtttgatg attatttcct tgtctattgg
    25621 ggaatctagc atgtcaccat tggaggtcgt cagggtgctt tttggtaaat ccactgctga
    25681 tatggccttg atcatcacca acattagact cccaagaatt ttagctgcct gtatcggtgg
    25741 cggctcactg gccctttctg gcttaatgct gcaaagctta acgcgaaatc atctggcaga
    25801 ttctggcata ctaggcatta atgctggtgc tggtatggct attacccttg tcatatccta
    25861 cagcactagt aacagtctga ccagcaggca agggctgccg cttatgacca tatccggggc
    25921 aatggcaacc attgtcttgg tctacctgct ctcacttcgt catggccata ttgatcctat
    25981 tcggctgatt gtcactggcg tagggctatc aaccatgcta tctagcctga tgattgcctt
    26041 tgtcggcaat gtgaaccgtt ataaggtgga ttatgtgatt cattggctaa gcgggcagct
    26101 aacaggcgat gattggtcca agctaagcat tgttgctccc ttattgggga tcacttggct
    26161 gctagccttt agtcaagcct ataagctcaa catcatggca ttaaatgatg aagcaagcat
    26221 ggctctaggc ttcaagctcc atcagtaccg taccattgtt cttgcactat ctgcgattct
    26281 ctcagcccta agtgttattt tggtcggaaa catcaccttt attggtctga tagcaggcca
    26341 taccagcaaa cgactagtgg gagctgatca ccgattaagc ctgcctgtca gccttttcat
    26401 cggcatgatt ctgcttctct tggctgacac tatcggacga gtctatctcg tcggcagcaa
    26461 tataccaacc ggtattcttg tctcaattat tggtgcatcc tattttctct atctgatggt
    26521 caaaatgaca taagagcctc tgctgcatag cttaaagggc tcagcaagca taaatggctt
    26581 agactcaact gttttacagt gtgggtctaa gccatttttt attcatcaag tcaactctta
    26641 atcagcgtag aaaatcagct gctccttatc aaaagccagc ttcaggcagt atttagtggc
    26701 ctctactttt tcaatatagc ctagaagctc caaggcattc acaaaaatat ctgtccgctt
    26761 ttgcataaca atctcttttc tagcaaattt tagaagaaag ctggtcatgt acttcaaggc
    26821 atagtcctga ttcacatcac ctaatagggc atagagcctt aattgctcat cagatagggc
    26881 ttcccctctt cttaagcggt aaaaataatt ggcaagcgtc agcttatctc ggtcaatggt
    26941 tgttttttcc ttgatcaaaa cctgattggt ctgattagac agcactgtct caaacaccaa
    27001 ggccatcaaa gcttcatata gatctgatgc cctatccaca aagattagat cttctaatgt
    27061 cacctgctgc aggtcatcta gcaagggcag acacagatag tagcgtctgt tttttcgaca
    27121 gatatagcca gcctgaatgt aagcttcaag cgccttatca atccccttaa catgagaaaa
    27181 ggcctgctta atgtgacgca gggttacgtc atcatgctga ttgaggtaat gaataaggtc
    27241 ttgaaaaaaa ggctgacgcg ttaatttatc agggttaaaa atggtaatca tactactatt
    27301 atagcaaaaa gaccaaaggg ctgctgataa aaatcaacac ccctctacag gcaagctcta
    27361 tgctccaaag ctttcagtta attgagggac aacctgcttt ttacgagata cagcacctgc
    27421 taggaaagca tgattatcct caagcttaaa gctaaaggct gcctcaacct tatccatatt
    27481 cgcaccaagc gccaaaatct ctgaatttga attaacaata tctgtaatca tcaagacaaa
    27541 atcagaatag ccctcacttg ccatcacctc tctaatagcg gcctcaatag cctccttgcg
    27601 ctctaacacc tctgcaatgt caacggtatt gacctgggct acacgaactg cgttgccatt
    27661 taattcaaag gtcttagcat caatatcaat caattctgct tctgatttac ttgcaaggtt
    27721 tgttccggcc tttagcatag ccataccgta ttcctctagc ttaactcctg ctaactctgc
    27781 taattccgca gcaacacgat gatctgaagc atgcgttgtt ggtgatttta acagcaaggt
    27841 atcagaaatc aagccagaca aaagcatgcc tgcaatgtcc tttggcacat caaccctatt
    27901 ttccttgaac aggcggtaaa caatagatga ggcagagcca acaggttcga cacgcatata
    27961 aagcggattt gctgtctcaa aattagccac ccgatggtgg tcaacaatac catacacctc
    28021 aacctcacga atatccgaaa tagactgtgg aaattcgtta tggtctgtta gaataacatg
    28081 actagcaccc tctgcttttg ctgatgtcac cactcttggt gctgataccc caaaatagtc
    28141 aagggcaaag gctgtttctt catttgggtc acccagagcg actacctccg tatccaaatc
    28201 aaaggctttt tttgctaagt agtcaaaagc atacgatgat gcgatggcat cagtatctgg
    28261 attttgatga ccaaaaacta atagttttga cataaagttt ctacctcatt ctctttattc
    28321 atcttattgt agcagaaata ggctctaaaa tcaaagaaga ttccccagtc acaggccaag
    28381 agtctaaagg gcataagggc acagaatctc aggtattaaa gagtcctgtc aaacacacaa
    28441 gaacaggcaa gccagtccaa aaagcaatgc cttctataat gagctattca gctatttggg
    28501 gacaatacac tgtccttgat tggtttaatg cttcaaggat tactttttgg cacgtgtctg
    28561 agctcgctta aaaacactga aggtctcatc aagccagccg cttcatcagc aaaaaaacgg
    28621 ctctataatt tccatggtgg atttacccac tacagaaatt atagagccca tttacctcgc
    28681 tttgcacatc acacaagaga aaacgagctt cgtctcgtgc ttagttatca gtcacccact
    28741 acagttgaca tggggccaaa aaaagctggg catttcccaa ctctagctta gcctatgatt
    28801 gatgaatacg gttcatgtat tcagtatagg attctgtatg cagcagcttt ttggcattct
    28861 ccacccgctc cttggttggt ggcttaacgc cctcaagctg gtatggaatc cctaactcgc
    28921 gccatttgaa ctctcccatc gtatgataag ggagtacctc aaacttgtcg acatttctca
    28981 aggtcttgac aaacgcatct aagcgtacca agtgatcatc aatgtctgtc aagccaggca
    29041 ccaagacatg gcgaatccag acgggcacct gcctatcaga gaggtagcga gcaaactgca
    29101 ggatattttt attgggctga cgggtgacaa gcttatgctg ctcctcgtca atctccttta
    29161 agtccagcaa aatcaaatca gtaactgcta ataatgtttc taacagctca tggtattcag
    29221 gggttggacg ataggcaaag ccacaggtat ctagcgttgt atggatacct agctttttgg
    29281 cctcagtaaa gagcgcagtg ataaagtcca tttgcagcat agcctcacca cctgacacag
    29341 tgattccacc ctttttcccc caaaagtgcc tatattgcag agcctccttt aggacatcat
    29401 taacggttcg gcgttgagat tgattggttt ccatagccca ggtgtccgga ttatggcaat
    29461 actggcaacg catcttgcag ccctgcaaaa aaatgataaa acgtatcccc ggaccatcaa
    29521 cagaaccaaa gctttctgta gaatgcacca ttccagttac ttgcccataa tctacttcaa
    29581 ccattgtgtc tccttcaccc ttgtaaatgg ttttacgttt tcattatatc atgtttcatc
    29641 aaaaagacta agctcaatgc ctagtcttca gtaatattct gttctatatt agaaatagta
    29701 agtttcaatt tggtgatacg accgtccttt actttgtcat tgaccaaaac cagatgcttt
    29761 tgcttgctat cacaggcaaa gctctctttc tccttttgac ttggaatggt accaatccct
    29821 gtcaaataaa agcccgcgat ggtatcgaca tcatcacttt ctaattctgt gtcaaaatac
    29881 tcgttaaagt cgttgagcgt cattgtccct gtgacaatat aggtgttgtc atcaatgtga
    29941 tgaacaaatt gctcagcctt gtctgtctca tcatcaatct caccaacgat ttcctcaagc
    30001 aaatcctcaa gcgtcaccaa acctgcaacc cctccgtact catcaagtag gatagccatc
    30061 tggttttgag tatttcgcaa ttgcctcaac aaatcatcta caaaaatcgt ttctggtaca
    30121 aagagcggct cctgcagaag ctttctcatg ctgatgtttt caaagccctg acgaaagcct
    30181 gattctaaaa gccttttggt atgaattaag ccgatcacct tgtccttgtc aacatcataa
    30241 actggaatac gagagaagct ctgctttagg atttccttga tattgtctag cgtatcatcg
    30301 ttaatgtcaa tcatgaaggc atctgtcctt ggaaccatca cctcacgcgc catcatctca
    30361 tcaagcgaga aaatcccctg cagcatttca atctcttcgg catcaagcgt tgcctcgctg
    30421 ttagtcagca tgtactcaat ctcatcacgc gtcatgcgct catctgcgtc atcaaaggtc
    30481 attggggtaa tccggctcag taaatttgtc gacgccgata agagccaaac aaagggacta
    30541 accaatttcc ccaagataat gatcactggg gcagaaatca cagcaagctt gtcttttaga
    30601 ttcatagcta tccgcttggg gtataactct cccaaaacaa tcgagacata ggtcaagaac
    30661 accaaagaaa taatgctacc agctgtttga gcggtcgcag aaccacctaa ccagccagaa
    30721 ataacctgcc ctaaagaggc tgacaggctc gcccctgaca agaggctaat aaaggtaata
    30781 ccaacctgaa tggtcgataa aaagttattg ggctgctcta aaacacgcag caagcgatca
    30841 tacctcttat ccccatcggc agccttttgc tccacacgag agcgatttaa ggataccaga
    30901 gccatctcac tggctgagaa aaaggcattt aacaaggtta gaatgactaa caataaaaac
    30961 tgaatcaata aaggctgact cacagggtct tccattaata taactcctaa aacataatat
    31021 actacttcat tatatcacaa ttgtcgccaa agattgctga tttatttctt tttcctgaga
    31081 aatcacagac agtctaagcc ctgacataag gctggctgaa gcttaatcag tagctgctat
    31141 tttttccagc atgattaaaa atggcggctg attcatctga ttgatcggct gatagagcat
    31201 tgctgttacc tggcgctgat tgagctgacc aatatagtcc aaaagctctt ccttctccct
    31261 actaccgcca tcatgaccat aatacaccat gatagcaatc cgtccaccta gctcaagccg
    31321 atcaagtatt ttagctaggg ctaatatggt cgtctcaggc cttgtgatca acgacttatc
    31381 tgcattgggt agatagccca gattaaaaat ggctgcccga atgggctcct taacatattg
    31441 atccacctgc tcgtgtccag ctaaaataag ctctgcatta gtcaagcctt gctgctccaa
    31501 gcgctcttgt gtcttggtca gtgcctgctg ctgcacatca aaagcataaa ccctttgtga
    31561 cagacttgct aaaaaggcag tgtcatagcc atttcccata gtagcatcaa cagcaatact
    31621 ctgcttatcc aaaacttctt ttaaaaattc atgtgataca tgaataggac gctttatcat
    31681 cttatcctcc taagcaaata cttcaaatgc cgcgatacca tctagtatgt ctaagtcaat
    31741 atgccttcgg ccgtaacaat ctagcacata atctttatac cgatctgttt ttagattgaa
    31801 ttgaagcgac cagatcagcc aaaaaagatc aatatgtcga tcgctttttc ctgcctcccc
    31861 ccaatcaatc atggactgaa attgccaccg atccaagatc atatttggca aacaaaaatc
    31921 cccatgaatc agagtttcat gctgtaacaa gagcttaagc tcctgaatcc gcctgtaagc
    31981 ctcctcctgg gactgaaacc gttgctgagg cggtaaaaag cactgattga accgcccttg
    32041 gtgataacca gcctcagcag cttcgatata ggctagcgtt ttgtcagcta caggaaaatc
    32101 agacaaagac aggctatgca gctttagcat atgatcaact aagatacgac ataagcgctt
    32161 gggatcggac aaatattcaa tatgactggc gtcctctcct gctacctttg cggttaaaag
    32221 ccaatcctga tcaccgctga tataatcaag cacctctgtt gctaagccct tactatgaca
    32281 ataccgagtt agggcggcct ccttggcaag cctaccttta gcggctgttt ttagaaaata
    32341 gccctgccct ttatcaatag cataaacacg tgcctctgcc gagctactgc tatcataaac
    32401 caaactgttt tgtaacagtt tttttaaaac aggtggtagg ctcagctcct ctcctgctat
    32461 caatctttgt ttcattgctt cccccgatta tcccttaagc ttacagccct gccagctatt
    32521 tcttctttcc atttctaggt caatcgcatt caaaacctcc catttattca ggctccacat
    32581 gggaccaatc agcatgtccc taggcgcatc acctgtgatg cgatgaataa tgatatgctc
    32641 aggtatgatt tctagctgat cacagataat cgatacatag tccttctgac tcaagagctg
    32701 caagcgtccc tcatgatagt ctctttgcat acgcgtattg gtcatcaggt gcagcaaatg
    32761 cagcttaatg ccttgaatat cattgtctgt gacacagcgt ctaacgtttt cgatcatcat
    32821 ctcatgggtt tcaccaggca agccattaat caagtgagac acaatgttaa tgttagggta
    32881 ctgcctcaga cgctgaaccg tttccttata caagtcataa gaatgcgccc gattaatcag
    32941 ctgggaggtg gcttcataag ttgtttgcag cccaagctcc actgtcacat gcatgcgctc
    33001 tgatagctca gccaaataag caatcgtctc atctggcaaa caatcaggcc ttgttccgat
    33061 attgatacca acaacgccag gctcattgat tgcttgctca tagcgctcgc gaataacctc
    33121 tagcttatca tgcgtattgg taaaattttg aaaataaacc aaatactgat tgacctcagg
    33181 ccacttgcga tgcataaaat caatttcttt gtaaaattgt tccctgatag gtgcatcagg
    33241 cgccacaatc gcatcacctg agccagaaac ggtacaaaag gtgcagccac catgagcaac
    33301 tgtcccatca cgattaggac agtcaaagcc agcatcaatg ggcaccttga aaattttagc
    33361 accaaataaa cgacgataat actcatttaa ggtctgatat ctttttgtca tgcctctatt
    33421 gtagcacaaa tcccccgatt aacagcagaa gatctcaatt ggctgctact tctctgattg
    33481 atgagccaaa gcaaggcaac taaaaaggat tgaagaagac ctctggaaga gacctgcctt
    33541 caatcactag cttttctaga actgatctgt aacgcgccat acagctgact gatcactgga
    33601 tttacttttg ctttagctga aaacgccatt caaagcgctt ttgatcataa aaaggataaa
    33661 gcagctgaag tatgccaaag cctaaggcat agccagccaa cacatcgcta ggataatgca
    33721 ctcccagata aatgcgtgac aagcctatca gcaaaatcaa ggccaaaagg gctatatcaa
    33781 ccagccagcg taaggaggct gactgcaatc tttgatggca aataatcagc agacttccaa
    33841 taatcaaaag gcttcccatc gaatggccac tcggaaaaga atagccagaa gcatgcacca
    33901 aatgctcaat gctgggtctt ggtctttgat acaagagctt tagcacccaa atcaaaaggg
    33961 ccgcaaaaac accatttgat aggacaaata aggcctcagc tctccagctc aaggccaata
    34021 aagccagcac agcaacaaca acaatcactg cctgtgtact aacatttcca gctacagtga
    34081 tccctttaaa aaactgggtt agcccttcag gcagatgacc tcttagggct aaccgaagct
    34141 gactatcaaa agacgttagg tcttcgggaa aaaatttaac aatatagcca agcaccacaa
    34201 atagtagcat agcaaaggaa gacaatagca gatgttgttg tttatgtttc atgatatgaa
    34261 ttcggatatc tctctaaaat tggtttacct gcaatataca cgaaataaaa gacaattgca
    34321 aatattagcc cctccaaaag gttgaaagga atgaccattg taaatatgta gcgagcagta
    34381 ccaataaaag ctttaatatc aaagccagca aacttggcat ataagggaat agcaaagaca
    34441 tagttcatga caaccatacc aagcgttaac agccctgtcc ccacaagact agctagtaca
    34501 taggtgacca gccctttctg acgatgccaa atcaaggcaa aggcagtgat aaaaagcgca
    34561 actgctataa cattcatcgg tataccaatc aaatcattaa cgccatgatt gtttaaggct
    34621 agtctaagca aggtcctcac cgctaaaatc aagttagctt gctttagatc catcaagacc
    34681 aagcctaaca aaatcggaat gatactaaaa tcaatcttta aaaagctggc tcctggaata
    34741 atggaaaacc ccacaaacat caggcaaaag gatatggctg aaagaatggc aaccatcacc
    34801 agttgatgtg tttttgacat aaaaaattcc tccaattttg acaaattgaa agaagctcct
    34861 tcgtatgagc aggcaaaaag tcaactcaaa aacccggtct tctctcttcc agactttact
    34921 gtcggttgtg gaatcacacc acatcagctt gcgctcgcgg acttctagct gcactagtca
    34981 ccgccggtcg ggaattacac cctgccctga agacacttat agcatagcaa atttaaacct
    35041 atagcgcaag acattttttt gaagcctagc ttttccaaca aacacaagac atcaggcaaa
    35101 aaagctagat gaaagcaaca gcaagaaaaa tcactttgag gctacaaagc tctctacgag
    35161 gtaggccacc ctgtgacatg gcactagcct agctcaaggc aaaaaagagc agactagaag
    35221 aaacctccaa taacctgctc tggtattact accgttgtcc cctttacggt catagacaca
    35281 cctaaccaat gaaaactcca atcagagttt tcagattgaa gaaaaagtcc attttagacg
    35341 gttttcttca atctttttct tttaatcaaa aaaacaaaag aagtctgaaa aatactgtaa
    35401 tatcagcatt tcccagagtt ttcatgatat gatagtcaat ttctaaatgt tcaatttttc
    35461 tatcgctgat agggtttgcc tacattctga actccaatcg gagttttttc tttttggctt
    35521 tagaaaacct ttggcacagc taatggctcc aaactggtga tggtgattca tcagccctct
    35581 agggcagcgc ctttgcttct tactgctgct cacaccgcaa gctctagcag tgtagtgact
    35641 gtagctggta ggacagtaag tccttcttgt ctcacatcag gctgctatag cccctgttct
    35701 gtgtcttgat cgc
//
LOCUS       DARYXW010000010        32116 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.010, whole genome shotgun sequence.
ACCESSION   DARYXW010000010 DARYXW010000000
VERSION     DARYXW010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32116
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.010"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            231..713
                     /gene="rimP"
                     /locus_tag="TV191_000401"
     CDS             231..713
                     /gene="rimP"
                     /locus_tag="TV191_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEL1506951.1"
                     /translation="MNIANTAIIDIVTQIVEPVIKAPYELVDIEYDKMGNDYVLSILV
                     DKASGITVEDTAELTELISPLLDTISPDPFPDQYMLEVSSPGLERPLKTAESLKAAVG
                     SYINVSLYRAIDKVKVFQGDLVAFDGDTLTIDYLDKTRHKTVEIPYQAVAKARLAVKL
                     "
     gene            823..1977
                     /gene="nusA"
                     /locus_tag="TV191_000402"
     CDS             823..1977
                     /gene="nusA"
                     /locus_tag="TV191_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEL1506952.1"
                     /translation="MSKEMLEAFRILEEEKHIDKADIIEAVTESLKSAYKRRYGQAES
                     CVIEFNDKTADFQVFTVREVVEEVFDSRLEISLNDALAISSAYELGDKIRFEESVSEF
                     GRVAAQSAKQTIMERMRRQMREITFNEYKQHEGEIMTGTVERFDQRFIYVNLGSLEAQ
                     LSHQDQIPGETFKSHDRIDVYVYKVENNPKGVNVFVSRSHPEFIKRIMEQEIPEVFDG
                     TVEIMSVSREAGDRTKVAVRSHNPNVDAIGTIVGRGGSNIKKVISKFHPKRYDAKTGL
                     EIPVEENIDVIQWVDDPAEFIYNAIAPAEVDMVLFDDDDLKRATVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEYERLEAEKEAAMTEAVATEELLTNEEV"
     gene            1993..2289
                     /locus_tag="TV191_000403"
     CDS             1993..2289
                     /locus_tag="TV191_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEL1506953.1"
                     /translation="MPKVKKIPLRKSLVSGEIIDKRDLLRIVKNKEGQIFIDPTGKQN
                     GRGAYIKLDNQEALMAKKKQVFNRSFSMEVPESFYDEVIAHVDHKVKRRELGLE"
     gene            2282..2584
                     /locus_tag="TV191_000404"
     CDS             2282..2584
                     /locus_tag="TV191_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEL1506954.1"
                     /translation="MNSLNRLSHLIGLAQRAKKVISGEELVIKAIRHQEVNLVFLAND
                     AGPNITKKVTDKSNYYNVEVSTVFSALELSAALGKPRKVVAIADAGFSKKMRTLMK"
     gene            2604..5474
                     /gene="infB"
                     /locus_tag="TV191_000405"
     CDS             2604..5474
                     /gene="infB"
                     /locus_tag="TV191_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEL1506955.1"
                     /translation="MSKKRLHEIAKEIGKSSKEVVERAKSLGLDVKSHASSVEEADAN
                     KIASSFSAGVTKNVQAGSAKDKQVAEQKAKAAKATTPQPAASKAAEKPAAATQEASQP
                     VAVKPKSRNFKAEREARAKEQVARRQAGQNRSNDRKSDYRQLGRSQGQQTERAGHKSQ
                     NQQRDRRFDNRPSSGNNRNDGHRQAGNRDKNRSFNANSRQQDTGRQGQTQAGAPKIDF
                     KARAAALKAEQNAEYARQRESRFREQEEAKRLEQQARQEAKAAALKAQTEDKKHREAS
                     AKATESVASMAAASVAKPVDKRRKKQNRPDKGHDRDHGLEDGQKKNKKSWNSQNQVRN
                     QKNSNWNNNKKNKKGKHHKNSNTAPKPVTERKFHELPKEFEYSEGMTVAEIAKRIKRE
                     PAEIVKKLFMMGVMATQNQSLDGDTIELLMVDYGIEAKAKVEVDEADIERFFTDDSYL
                     NPENIVERAPVVTIMGHVDHGKTTLLDTLRNSRVATGEAGGITQHIGAYQIEEAGKKI
                     TFLDTPGHAAFTSMRARGASVTDITILIVAADDGVMPQTIEAINHSKAAGVPIIVAIN
                     KIDKPGANPERVISELAEHGIISTAWGGECEFVEISAKFNKNIDELLETVLLVAEVEE
                     LKADPTVRAIGTVIEARLDKGKGAVATLLVQQGTLHVQDPIVVGNTFGRVRAMTNDLG
                     RRVKSAEPSTPVSITGLNETPMAGDHFAVYADEKAARAAGEERAKRALLKQRQNTQRV
                     SLDNLFDTLKAGEIKTVNVIIKADVQGSVEALAASLLKIDVEGVRVNVVHSAVGAINE
                     SDVTLAEASNAVIIGFNVRPTPQARQQADTDDVEIRLHSIIYKVIEEVEEAMKGKLDP
                     EYQEKMLGEAIIRETFKVSKVGTIGGFMVVNGKVTRDSSVRVIRDSVVIFDGKLASLK
                     HYKDDVKEIGNAQEGGLMIEGFNDIKVDDTIEAYVMEEITRK"
     gene            5664..6014
                     /gene="rbfA"
                     /locus_tag="TV191_000406"
     CDS             5664..6014
                     /gene="rbfA"
                     /locus_tag="TV191_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEL1506956.1"
                     /translation="MTNHRIDRVGMEIKREVNEILHKKVRDPRVQGVTITEVQMLGDL
                     SVAKVYYTIMSDLASDNQKAEIGLKKATGTIKRELGKQLTMYKIPDLVFEKDNSIAYG
                     NKIDQLLRELEKKQ"
     gene            complement(6086..7123)
                     /locus_tag="TV191_000407"
     CDS             complement(6086..7123)
                     /locus_tag="TV191_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEL1506957.1"
                     /translation="MIKEKTLTYLKRQLILLALLLTAIGSQTIVQASTRSWKSWFIEQ
                     YFWLKRDKSYYAEQDENTFYNYVKSAGEKSNQGFNLTQNEVNGTLKTEYRDNMQVHSW
                     NENSTNPSNQKVILYLHGGSYLNNPTSYHIDMLKTLSTSLDAKIVLPIYPKAPTYTYD
                     VAMPRLVSLYQDILKSTNNNANNITIMGDSAGGGLALGLALALKNEDIKQPKDIILLS
                     PWLDVTLSNPEIPNYEASDPILSAWGLRIVGDIWARRGENNTKHPYVSPIYGDTSNLA
                     PITMFVGTHEIFYPDITKFDGMLKQKGHKHQLFVGEKMNHVYPIYPIEEAKTAQYQII
                     DTIKKEYEPQK"
     gene            7353..7787
                     /locus_tag="TV191_000408"
     CDS             7353..7787
                     /locus_tag="TV191_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEL1506958.1"
                     /translation="MDTISDAEWEVMRVVWANGSMKSSEIIAILHEKHHWSDSTVKTL
                     IGRLVKKKALRADRQGRSYIYQSLLDQDRRQLAMLRERLDGMCQRHHSRLLLALLKDT
                     PMTLEDIQAFQLLLEAKKVGAVSHVRCDCVPGQCHCQKKERI"
     gene            7787..10018
                     /locus_tag="TV191_000409"
     CDS             7787..10018
                     /locus_tag="TV191_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HEL1506959.1"
                     /translation="MVKETYLLEGMHCTSCALAIEQAVKQLPGVEGAAVDVTTEKLSV
                     SYSTDSLSSAELIQAVRKAGYRAELLDETNMRGQLERLEEQASNEWYRFLWSALFSLP
                     LLYLAMGPMLGLVLPVALAPQSHAISYGLVQLLLTLPVLFLNRQYYENGFKALIKKRP
                     NMDSLVTLATSFAFIYSSYSCFKIVAGAAQFAHQLYFESVVVILTLITLGSYLEGRTK
                     GRASQAIQKLMSLRVTDVRVIREGALQLIPLEQVTNEDICFIQPGERVAVDGLIVEGQ
                     STVDESMLTGESLPVDKVTGDSVFAGTINGQGALRVKPSRLGNDTLLSQIIELVEQAQ
                     QAKAPIAALADRVSGVFVPIVLSLSLLSFLFWLFVMRESFDFALTIAIAVLIIACPCA
                     LGLATPTAIMVGSGRAAEQGILFKGGDILEKAYQVRTIVFDKTGTLTEGQAQLQRIIP
                     LAASEKQGLQEVASLEQYSQHPLGEALVRVAQEKGYDLLAVTDFQSLVGLGVTGVIDQ
                     HRLAVGNSELMSQQGIAISAAQTYAEQAALKGQTVVYYAKDNQLCALLLIADRLKADS
                     KAAIRALQDLGLQTVMLTGDNALTAQAIANEVGIDQVFSQVLPAQKAQIIADLKASGQ
                     LVAMVGDGINDAPALTLADIGISIGSGTDIAIEAADVILMTSAVRDVVECLELSRQTI
                     RVVKQNLFWAFSYNSLMIPVAMGILHVFGGPLLSPMLAGFAMSLSSISVVLNALRLRH
                     KKW"
     gene            10889..11839
                     /locus_tag="TV191_000410"
     CDS             10889..11839
                     /locus_tag="TV191_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3137 domain-containing protein"
                     /protein_id="HEL1506960.1"
                     /translation="MNENTKRLTDPIVLEKSRAIEASPEHHQKLEQIKSEMSGNARKN
                     NLGWLAMVIGAIILYGMVDRSLALFLIIFVGGLVWPRLKTFKTANELSYVDHFLLPVL
                     QEALPDVKIDYYSGIELSLLKLATPSSRWYDSNCHIIFGDDMQTEFCNLYAYHEENED
                     DNWHRVTDFNGQVLLAKYHTAIKGYIRIVPTQKGFLGREKVHSGYKAKLKGEVQLEME
                     DIRFNETYNVYCTDELSARMLLNPYMLAVLDEWREEMPVAVYMNGDTVVVSFYSGQQL
                     LKTPSSRGAIEKLSLSSEYENIQDKLVKMYRLLDTLNHQL"
     gene            11852..12403
                     /locus_tag="TV191_000411"
     CDS             11852..12403
                     /locus_tag="TV191_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEL1506961.1"
                     /translation="MSVTSSMLTLILCMTILWLIGVRNKLERYRIVIEESKRNVDIAL
                     EKRYDTISEMLKIAKSYAKHEEKVFTELVKLRQGLSLEETNDVMRTQEQALNEVFAVG
                     EAYPEMRSSEQFLSLQNEIAKENAALAAAKRIVNSNISLFNQAVVAFPVSIVASLINI
                     KQMTFLDIDLDHKKSLDQLDYTI"
     gene            complement(12819..13601)
                     /locus_tag="TV191_000412"
     CDS             complement(12819..13601)
                     /locus_tag="TV191_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEL1506962.1"
                     /translation="MLKRERLLTIMEKVNANGFITVTDIMESLRVSDMTARRNLDELA
                     RAGKLVRIRGGAQSISMPQKLERSNTEKLTVQIEAKKEIARYASQLINDGETIFIGPG
                     TTLECLAEALINRHIRIITNSLPVFTILNKSKTVDLILIGGEYRAITGAFVGSLASQT
                     ILSLKFAKAFISCNGIYKNDIATYSENEGVIQRLACDNAIEKYLLADNQKFNAYDFYS
                     FYHLDNIDAIITDSKISDSVKERYRQFAKLLIARPADNQVSS"
     gene            13737..14162
                     /gene="lacA"
                     /locus_tag="TV191_000413"
     CDS             13737..14162
                     /gene="lacA"
                     /locus_tag="TV191_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEL1506963.1"
                     /translation="MTIILGADAHGNDLKEAIKGFLQQEGFDVTDVTAIADDFVDNTL
                     AVARALKADEESLGIMIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNARMIT
                     MGAEIVGQELAKNIAKGFVTGHYDGGRHQIRVDMLNKMA"
     gene            14178..14693
                     /gene="lacB"
                     /locus_tag="TV191_000414"
     CDS             14178..14693
                     /gene="lacB"
                     /locus_tag="TV191_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEL1506964.1"
                     /translation="MKIAIGCDHIVTDEKMAVSDFLKSKGYEVIDCGTYDHTRTHYPI
                     FGKRVGEAVANGLADLGVCICGTGVGITNAVNKVPGIRSALVRDMTTALYAKEELNAN
                     VIGFGGKITGELLMCDIIEAFIKADYKETEENKKLIAKIAHLESHNANQEDPDFFTEF
                     LDKWDRGDYHD"
     gene            14703..15635
                     /locus_tag="TV191_000415"
     CDS             14703..15635
                     /locus_tag="TV191_000415"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEL1506965.1"
                     /translation="MILTVTLNPSIDISYPLNRLTLDTVNRVDRTTKTAGGKGLNVTR
                     VLAEAGQSVVATGFIGGKLGDFVIHQLQEQGISNQFFKIKGETRNCIAVLHEGMQTEI
                     LEAGPYIDMDEAEGFLNHMSIIAKQFDVLTFSGSLPKGLAAHYYQDLITMARVYGSKV
                     VLDCSGAPLKAVLAGKDKPTVIKPNLEELEDLIGQPVTLDEERLISLLSQPLFEGIEW
                     IIVSLGAQGAFAKHHNRFYRVTIPKIEVVNPVGSGDATVAGIAWALAEGDDDETLLKK
                     ANVLGMLNAQETRTGHVNMAHFDELFDRIQVEEV"
     gene            15637..15903
                     /locus_tag="TV191_000416"
                     /pseudo
     CDS             15637..15903
                     /locus_tag="TV191_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003106440.1"
                     /note="catalyzes the reversible reaction of
                     dihydroxyacetone phosphate with glyceraldehyde 3-phosphate
                     to produce tagatose 1,6-bisphosphate; in Streptococcus
                     pyogenes there are two paralogs of tagatose-bisphosphate
                     aldolase, encoded by lacD1 and lacD2; expression of lacD1
                     is highly regulated by environmental conditions while
                     lacD2 specializes in an efficient utilization of
                     carbohydrate sources; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
     gene            15906..16391
                     /locus_tag="TV191_000417"
                     /pseudo
     CDS             15906..16391
                     /locus_tag="TV191_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515109.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
     gene            16602..17474
                     /locus_tag="TV191_000418"
     CDS             16602..17474
                     /locus_tag="TV191_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEL1506966.1"
                     /translation="MKKVMMSLLILATATLGACQASHQSDQPKQEQKEPQAKKGRLFL
                     SNMNSAKSQQEVRAALSHQLKEANVNAFMAGVQEYNSLVGKTGLTGAFTYQKQPDYDV
                     VAIDELWSQKQGNFIGTNCRINTFMLLKDSMTIAPTSSDDTLLFMDEDAITTSQLFTQ
                     AETERFKQLFSRVKTEATKDIQVHAKHMQEHFSAVSFNGPAKMLAVVIHDQLDGDYLF
                     IGHVGVLVEYKSKYLFVEKLSFQEPYQAILFDQKQDCYQYLYHKYKTYQTKTSAEPFL
                     MENNKAVNLASYRS"
     gene            17635..18249
                     /locus_tag="TV191_000419"
     CDS             17635..18249
                     /locus_tag="TV191_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric intracellular cation channel family
                     protein"
                     /protein_id="HEL1506967.1"
                     /translation="MTIDMWELLSIIGTIAFALSGAIVAMEEEFDVLGIFILGFVTAF
                     GGGAIRNTLIGLPIEALWGQRPEFACAFIAIILIMLFPKLVAKGWVRAAVLTDAIGLA
                     AFSVQGALHAVRLAQPLSAVIVAAVLTGAGGGVVRDVLAGRKPTVLRSEIYAGWSIIA
                     ALVLYFKLATSNVECYLLVVLLTVMRMIGNKRQWHLPKIKWKED"
     gene            18254..19078
                     /locus_tag="TV191_000420"
     CDS             18254..19078
                     /locus_tag="TV191_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL1506968.1"
                     /translation="MIQLIAIDLDGTLLDSKKHIPKENIKAIQAAAQEGIKVVLCTGR
                     PQSGTRPYFEQLGLSDKEEYLILNNGCSTYRSPSWELLHYQSLTFSAIEHLYQLSQPF
                     SDIYLTLTGERDYLVIDSKVPDMVQADGDLVFTKVKATNLSQLSNSSQIIFQAMYMGE
                     KAALDTFEALVREKLSASFSVVRSQETILEVMPECVTKASALKELTADLKLRPDQVMA
                     IGDAANDLEMLAYAGLGVAMGNADEAIKKVADKVSLSNDQAGVAHAINQFALTKGS"
     gene            complement(19489..20046)
                     /locus_tag="TV191_000421"
     CDS             complement(19489..20046)
                     /locus_tag="TV191_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEL1506969.1"
                     /translation="MAGKPISKQSLQNLAHCNQESRRLTREAIEIALLSLLEKKPLGH
                     ITISELVARAGVSRNAFYRNYSSKEDILECLLTSVIRRIFRGLKAFDLKTQAYQAWLY
                     LFTEAKKEATLLSIIFNHHLQQLLTQMVTKRLRAYQKWQEKKLSHYALLFWSNAIVSV
                     LSNWISDDMVVPAEEMAAMGLPLLA"
     gene            20178..21020
                     /locus_tag="TV191_000422"
     CDS             20178..21020
                     /locus_tag="TV191_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL1506970.1"
                     /translation="MTWKIVSDSGCDIRALKSQSNHLRFERVPLTLQIGSDIFRDDDG
                     LDIDQMMETMYQSSKPATSSCPSPDAFLQAYRGADNVIAITITGTLSGSHNSARLAQN
                     DLLEENPNANIHVIDSLSAGGEMDLIVLELERLINQGLSFDEVVEKITAYQEKTRLVF
                     VLAKVDNLVKNGRLNKLIGKVIGLLNIRMVGQASKEGTLELLQKARGQKKAVSAVLEE
                     IQKAGYKGGRVFISHAKNPKICEQIAEKIRAIYPEAEIQTSPASGLCSFYAEAEGLLM
                     GYEV"
     gene            complement(21626..22372)
                     /locus_tag="TV191_000423"
     CDS             complement(21626..22372)
                     /locus_tag="TV191_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1506971.1"
                     /translation="MRKPTKETHYLIISLLTIAIAGGAYLIFSSLSPKPATITTQSKG
                     YELLTKAQALVKEAEDNPTKEAIAKAQKAINQLKKTQSKEELQARLTAISLKHNQEDV
                     AIKVLKAAEDNPSPELKEAAQKAISKLSDEAKKAALQARLDAIGLSKPSTAQPETATP
                     AAEKNIAPAPAAPQIKHTTPSSGGTTPAPNPKPSPKPNPQPSPSPAPENPEPTPSPNP
                     QPNPQPETNTPSPQPPATEQSENTAPAGQN"
     gene            22563..24204
                     /locus_tag="TV191_000424"
                     /pseudo
     CDS             22563..24204
                     /locus_tag="TV191_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983536.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
     gene            24321..25469
                     /gene="nagA"
                     /locus_tag="TV191_000425"
     CDS             24321..25469
                     /gene="nagA"
                     /locus_tag="TV191_000425"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEL1506972.1"
                     /translation="MTSYIKADCFYYPNEVKPAGYLELNNGTFGYWTATVDDQAEVID
                     YTGYQIAPGLVDTHIHGYAGADVMDNSAEGLHAISEGLLSTGVTSFLPTTLTSTFEHL
                     EQVSATVASVADQVKGAKIQGIYFEGPYFTEEYKGAQNPIYMKNPRLDEFAAWQKAAK
                     GLIKKIALAPERDGVEAFVSEVTKQGVTVALGHSNGTYTEAKKAVAAGASVWVHAYNG
                     MRGLTHREPGMVGAVYNIPGTVAELICDGHHVSPVACDILMQQKGHEHVALITDCMRA
                     GGSPDGDYMLGEFPVIVENGTARLKDSGNLAGSILKLKDGIKNVVAWGIASPAEAIHM
                     SSYVPAASVGIEDVCGQIKAGHAADFIVLDKDLELVATYLNGQKAFEA"
     gene            25556..26395
                     /locus_tag="TV191_000426"
     CDS             25556..26395
                     /locus_tag="TV191_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEL1506973.1"
                     /translation="MIKTVTMANGLAIPVLGFGTFKAADGEEAYQSTLAAIKAGYRHI
                     DTAAIYHNEKSVGQAIRDSGVPREELFITTKLWNDAHSYDGAKAALAASLERLGLEYV
                     DLYLIHWPNPKALRDCWQAANAAAWSYMEEAVEAGLVRSIGVSNFMVHHLEALKQTAT
                     ITPAVNQIRLAPGCYQKETVDYCRRHHILLEAWGPLGQGEIFADDTMQALAKKYNKTV
                     AQLALAWSIAEGFIPLPKSVHKERIVENMAIFDCEISPEDSERIRCLPGMSAIPDPDT
                     KDF"
     gene            26425..26649
                     /locus_tag="TV191_000427"
                     /pseudo
     CDS             26425..26649
                     /locus_tag="TV191_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515130.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            26916..27449
                     /locus_tag="TV191_000428"
     CDS             26916..27449
                     /locus_tag="TV191_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEL1506974.1"
                     /translation="MIILLLMLLMFAIRLVFLKKSIKNEKAILANGGKEFGAQNTKFL
                     TLLHIMIYVFAVTEALLKQIKFDGISFLGLLLMIFSIAVLYEVTRILGDIWTVKLMLA
                     KDHKYVDHWLFKTVKHPNYFLNIAPELVGIALLCHAQITAMLLFPCYIIVIYLRIREE
                     NRLLSEVIIPNGTRPKS"
     gene            27815..28726
                     /gene="glyQ"
                     /locus_tag="TV191_000429"
     CDS             27815..28726
                     /gene="glyQ"
                     /locus_tag="TV191_000429"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEL1506975.1"
                     /translation="MSNKLTFQEIILTLQQYWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLQSLER
                     LGIDPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAE
                     VTYGLERLASYIQEVDSVYDIEWAPGVKYGEIFLQPEYEHSKYSFEVSNQDMLLENFE
                     IFEKEAERALAQGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRHLARSVA
                     KTFVAERKKLGFPLLDDASRVALLAED"
     gene            29092..31131
                     /locus_tag="TV191_000430"
     CDS             29092..31131
                     /locus_tag="TV191_000430"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014712716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEL1506976.1"
                     /translation="MTKDLLVELGLEELPAYVVTPSEKQLVERMADFLKANRLSYDAI
                     EGFSTPRRLAVRVLGLADQQTDLTEDFKGPSKKIALDADGQFSKAAQGFVRGKGLTVD
                     DIEFREVKGEEYVYVTKHEAGKQAKDVLAAVPEVLASLTFPVSMHWANNSFDYIRPVH
                     SLIVLLDDEPLELDFLDIHSGRISRGHRFLGEETSITSADSYEADLRSQFVIASAKER
                     QEMIIAQIRAIEAEQKVQVDIDEDLLNEVLNLVEYPTAFMGSFDPKYLEIPEEVLVTS
                     MKNHQRYFVVRDQAGKLMPNFISVRNGNAKHLQNVIKGNEKVLVARLEDGEFFWREDQ
                     KLSIEDLVAKLAHVTFHEKIGSVAEHMERTKVIAAFLADQAGLSEAEKSAVARAAQIY
                     KFDLLTGMVGEFDELQGIMGEKYALLTGEAAAVATAIREHYLPNSAEGELPETKVGAV
                     LALADKLDTLLSFFSVGLIPSGSNDPYALRRATQGIVRILEHFGWSIPMDKLIDSLYE
                     LSFDSLTYQHKAEVLDFICARVDKMMGSAIPKDIREAVLASSSFVVPELLARAEALAA
                     ASQLDTYKPAVESLSRVFNLAKKAVDAVLIDASLFENDYERALAQAVDSLVLSGSAKE
                     QLAQVFALSPVIDDFFDHTMVMTEDEAIRRNRLALLAELVKKVETIAAFDRLNTK"
     gene            31668..31925
                     /locus_tag="TV191_000431"
     CDS             31668..31925
                     /locus_tag="TV191_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEL1506977.1"
                     /translation="MDPKKIARINELAKKKKTVGLTGPEKVEQAKLREEYIEGYRRSV
                     RHHIEGIKIVDEDGNDVTPEKLRQVQREKGLHGRSLDDPES"
BASE COUNT         9041 a         6191 c         7867 g         9017 t
ORIGIN      
        1 ggataaggaa agagaaaaaa gcaaggttaa agatctcctc tccttttaaa aaataggatt
       61 tttgaggtct tattgacact tttagtaggg attttcttgc aattcatttt gattgtggta
      121 taataggtta aagcaataca gaagggtggt gagaaatatc tcgccacttt tgtgttgatt
      181 atcaagagga caaggctata gaggtatagc agtcatcagt aaaggaggtt attaacatcg
      241 caaacacagc tattattgat attgttaccc aaatcgtaga acctgtaatt aaagcaccct
      301 atgaattggt cgacatcgaa tacgacaaaa tgggcaatga ttatgtcctt agtatcttag
      361 ttgataaggc ttctgggatt accgttgagg atactgctga gcttacagag ctaatcagtc
      421 cactcttaga tacgatttct ccagaccctt tcccagatca gtatatgctg gaggtttcca
      481 gtcctgggct agagcgtcca ttaaagactg ctgagagctt gaaggctgct gtaggctcat
      541 atattaatgt cagcctctat cgggcaattg ataaggtgaa ggtttttcaa ggagatttag
      601 tggcttttga tggtgatacc ctaaccattg attatctaga taagacgcgt cacaaaacag
      661 ttgagattcc ttaccaagca gtggctaagg ctcgtttagc tgtcaaatta taaggcaatt
      721 gctgagcgat ttgctttagt cggttggcta agccctaaat ggattaattt ataagataag
      781 aaaggatttt taccaagctt tgagagcaag gtagacaaca ttatgagcaa agaaatgcta
      841 gaagccttcc gtattttgga agaagaaaaa cacattgata aggcagatat cattgaggca
      901 gtcactgaat cactgaaatc agcttataaa cgtcgttatg gtcaagcaga atcctgcgtc
      961 attgaattta atgataaaac agcagatttt caggttttta cggttcgtga ggttgttgaa
     1021 gaggtatttg atagccgtct ggaaattagc ctgaacgatg cccttgccat tagctcagcc
     1081 tatgagttag gagataagat tcgttttgaa gaatcagtca gcgagtttgg acgtgtggct
     1141 gctcaatctg caaagcaaac cattatggaa aggatgcgtc gtcagatgcg agaaatcacc
     1201 ttcaatgagt acaagcagca tgaaggtgaa atcatgacgg gtacggttga gcgttttgac
     1261 caacgtttca tttatgttaa ccttggttcc ttagaggctc agctctcaca tcaggatcaa
     1321 atcccaggag aaaccttcaa atcacatgat cggattgatg tctatgtcta caaggtggaa
     1381 aacaatccaa agggggttaa cgtctttgtt agtcgtagtc accctgagtt catcaagcgc
     1441 attatggaac aggaaattcc agaggttttt gatgggaccg ttgagattat gagtgtttct
     1501 cgtgaggctg gtgaccgtac taaggttgct gtgcgtagcc acaatcccaa tgttgatgcg
     1561 attggaacga ttgttggtcg tggcggcagc aacatcaaaa aggttatcag taaattccat
     1621 ccaaagcgct atgatgctaa gacaggactt gagatcccag tagaagaaaa tattgacgtt
     1681 atccaatggg tagatgaccc tgctgaattt atctacaatg ccattgcacc tgctgaggtt
     1741 gatatggttc tctttgatga tgacgatctt aagcgtgcga ctgtggtggt gcctgataat
     1801 aagctatcgc ttgctattgg tcgtcgtggt caaaacgttc gtttggcagc tcatttgaca
     1861 ggctatcgca ttgacatcaa atcagccagt gaatatgaac gccttgaagc agaaaaagaa
     1921 gcagcaatga ctgaagcagt agctacagag gagctcttaa ccaacgagga agtgtaagaa
     1981 aagaggtgtt ttatgcctaa agtaaaaaaa atacctttac gtaagtcgct tgtttctggt
     2041 gagatcattg ataagcgtga cctccttcgt attgtcaaaa ataaggaggg gcagattttt
     2101 attgatccaa ccggcaagca aaatgggcgt ggtgcttata tcaagctaga taaccaagaa
     2161 gcacttatgg caaagaaaaa acaggtgttt aatcgtagct tctcaatgga ggtgccagag
     2221 agcttttacg atgaagtgat tgcacatgtt gatcacaaag ttaaaagaag agagctaggc
     2281 cttgaatagt ttaaatagat tatctcattt gatcggactg gctcagcggg ccaaaaaagt
     2341 gatttcaggt gaggaattgg tcattaaagc cattcgacat caggaagtca atcttgtttt
     2401 tttagccaat gatgctggcc caaatatcac taaaaaagta acagataaaa gtaattatta
     2461 caatgtagaa gtctccacag tgtttagtgc actggaatta agtgctgcac ttggcaagcc
     2521 tcgtaaggtg gttgccattg cagacgctgg attttcaaag aaaatgagga ctcttatgaa
     2581 atagacgaat aggaggacac aaattgtcaa agaaaagatt acatgaaatt gccaaggaaa
     2641 ttggcaaaag tagtaaagaa gtcgttgagc gtgctaaatc cttaggatta gatgtcaaaa
     2701 gccatgcgtc aagcgtcgaa gaagcagatg ctaacaaaat tgcctctagc ttttcagcag
     2761 gtgtgactaa gaatgttcaa gcaggttcag caaaagacaa gcaagtagca gaacaaaaag
     2821 caaaagcagc taaggccact acaccacagc cagcagcctc taaagcagca gaaaagccag
     2881 ctgctgcgac acaagaagca tcacagccgg ttgctgttaa gccaaagagc cgcaatttca
     2941 aggcagagcg tgaagcacgt gccaaggagc aggtagcgag acggcaggct gggcaaaatc
     3001 gctctaatga ccgcaagtca gactatcgtc aacttggacg atcacaaggt cagcagacgg
     3061 agcgagctgg ccacaagtca caaaatcagc aaagagatag acgctttgat aacaggccat
     3121 catctggaaa taaccgaaac gatgggcata gacaagctgg taatcgtgac aaaaaccgtt
     3181 cctttaacgc taatagtcgt caacaggata caggacgtca agggcagacc caagccggtg
     3241 ctcctaagat tgattttaag gcgcgtgctg ctgccttaaa ggctgagcaa aacgcagagt
     3301 atgccagaca aagggaatca cgctttcgtg agcaagagga ggctaaacgc ttagagcaac
     3361 aggcaaggca agaggctaag gcagccgccc tcaaggctca gacagaggac aaaaagcatc
     3421 gtgaagcctc agctaaggct actgagtcgg ttgctagtat ggctgctgca tcggtagcaa
     3481 aaccggttga taagcgtcgt aaaaaacaaa atcgtccaga caaagggcat gatcgggatc
     3541 atggcctaga agatggacaa aagaaaaata agaagagttg gaatagtcaa aaccaagtga
     3601 gaaatcaaaa gaatagtaac tggaataaca acaagaaaaa caaaaaaggt aagcatcata
     3661 agaatagcaa cacagctcca aaaccagtaa cagagcgtaa attccatgaa ttaccaaaag
     3721 aatttgaata ttcagaagga atgaccgttg ctgaaattgc aaaacggatc aagcgtgagc
     3781 cggctgagat tgtcaagaaa ttatttatga tgggtgtgat ggcaacgcaa aaccaatcct
     3841 tagatggtga taccattgag ctcttaatgg tggattatgg cattgaagct aaggccaagg
     3901 tggaggttga tgaagctgat atcgagcgct tctttactga tgatagctac cttaatcctg
     3961 agaatattgt tgagcgtgca ccggttgtta ccattatggg acacgtcgat catggtaaga
     4021 cgaccctgct tgataccctt agaaattctc gtgttgcaac aggagaagca ggagggatca
     4081 cccagcatat tggagcttac cagattgagg aggcaggcaa gaagattacc ttcttggata
     4141 caccaggaca tgctgccttc acaagcatgc gtgcacgtgg agcgtcagtg acagatatta
     4201 ccattttgat tgtagctgct gatgacgggg taatgccaca aaccattgaa gctattaacc
     4261 attctaaggc ggctggtgtt ccaattatcg ttgccatcaa caagattgac aagccagggg
     4321 ctaatcctga gcgtgttatt tcagaattgg ctgagcatgg gatcatctca actgcttggg
     4381 gtggtgagtg tgagtttgtt gaaatctctg ccaaatttaa caaaaacatt gatgagctgc
     4441 tagaaacagt gcttttggta gctgaggttg aagagctaaa ggctgatcct acggttcgtg
     4501 cgattggtac ggtcattgag gctagacttg acaaaggtaa gggtgcggtt gcgacacttc
     4561 tggtccaaca aggaacccta cacgtacaag acccaatcgt tgttggtaac acctttggtc
     4621 gtgtgcgtgc catgacaaat gaccttggtc gtcgtgtgaa atcagctgag ccgtccacac
     4681 cggtatctat tactggtctc aatgaaaccc ctatggcggg tgatcatttt gcggtctatg
     4741 ctgatgaaaa agcagcgcgt gcagcagggg aggagcgtgc taagcgtgcc cttctcaagc
     4801 aacgtcaaaa cacgcagcgt gtcagccttg ataacctatt tgataccctc aaggcagggg
     4861 aaatcaaaac cgttaacgtg atcatcaagg cagacgtgca gggctctgtg gaagctttgg
     4921 cagcctcact ccttaaaatt gatgttgagg gcgttcgagt aaatgttgtt cactctgctg
     4981 tcggtgcgat caatgagtca gatgtgacct tggcagaggc ttcaaacgct gttatcatag
     5041 gcttcaatgt gcgtccaaca ccacaggcgc gtcagcaggc tgatacagac gatgttgaga
     5101 ttcgcttgca tagcattatt tataaggtga tcgaagaggt tgaggaagcc atgaaaggta
     5161 agcttgaccc tgagtatcaa gaaaaaatgc ttggtgaggc tattattcgt gaaaccttta
     5221 aggtctctaa ggttgggaca atcggaggct ttatggttgt taatggtaag gtaacgcgtg
     5281 attcaagtgt acgtgtcatt cgtgatagcg tggttatctt tgatggtaag ctagccagtc
     5341 ttaagcatta taaggacgat gttaaggaga ttgggaatgc ccaagagggt ggtttgatga
     5401 ttgaaggctt taatgacatt aaggtcgatg ataccattga ggcttacgtc atggaagaaa
     5461 ttacccgtaa ataatcgtgg tggctagtag cttaaatagc ctcgtctcaa gacaatagac
     5521 aatgtcacca cttgatttga acagtcacta ttaatagtat agccatcagc ctaatagaga
     5581 aaaaggcttg aaagtcatca agcttttctc ttgttattga gctactgaga gcctgtacta
     5641 tttgacaata gaaaggaagg gccatgacaa atcatcgtat tgatcgtgtt ggtatggaaa
     5701 tcaagcgtga ggtcaacgag attttacaca aaaaggttcg tgatccacgt gtgcagggtg
     5761 ttacgatcac agaagtgcaa atgctgggcg atttgtcagt tgctaaggtt tactatacca
     5821 ttatgagtga cctagcttca gacaatcaaa aggctgaaat aggcttaaaa aaagcaacag
     5881 gaaccattaa gcgtgagctt ggtaagcaat taaccatgta taaaattccg gatttggttt
     5941 ttgaaaagga caattctatc gcctatggta ataaaattga tcaattgctc cgtgagctag
     6001 aaaagaaaca gtagtcatgc tgtgatcaga aaatgcctac caggctttgg caaaaaactc
     6061 aagtctggta ggcatttttg tattattatt tttggggttc gtactctttt tttatggtat
     6121 caatgatttg gtattgtgct gtcttggcct cttcaatcgg gtaaatagga taaacatggt
     6181 tcatcttttc cccgacaaat agctggtgct tatgtccttt ttgttttaac ataccatcaa
     6241 attttgtaat gtctgggtag aagatttcat gagttcctac aaacatggtg ataggtgcta
     6301 ggttgcttgt atctccatag atagggctaa cataagggtg cttagtgtta ttttccccgc
     6361 gtcgtgccca gatatcacct actatgcgca gtccccaagc cgataagata ggatcagagg
     6421 cttcgtaatt tgggatctct ggatttgata gggtgacatc aagccaaggt gagagcagga
     6481 taatgtcctt aggctgctta atatcttcat ttttcaatgc tagtgccaaa cctagtgcca
     6541 gaccgcctcc ggctgagtct cccatgatgg tgatattgtt agcattgtta ttagtgcttt
     6601 ttagaatatc ctgataaaga ctaactaatc ttggcatagc gacatcatag gtataggtcg
     6661 gagcctttgg gtaaatcggc aatacaatct tagcatcaag gctagttgac aaggttttga
     6721 gcatgtcaat atggtatgag gtcgggttgt ttaggtagga gccaccatgc agatagagaa
     6781 tgaccttttg atttgatgga ttagtagagt tttcattcca gctgtgaacc tgcatgttgt
     6841 ctctatactc tgtctttaat gttccgttga cctcattttg agtgagatta aagccttgat
     6901 tgctcttttc accagctgac ttgacgtagt tgtagaaggt attctcatcc tgctcggcat
     6961 aatagctttt gtctcgttta agccaaaaat attgctcaat aaaccagctt ttccaggatc
     7021 gcgtgctggc ctgaacgatt gtttggctac ctatagctgt gagtagaagg gctagtagaa
     7081 ttagctgtct tttaagatac gtcaatgttt tctccttaat cattacagta ttactgtcat
     7141 atagtaatat acaaggactc attttgtcaa tataaagtta atcagataag actggaaagt
     7201 tcagactatt aaaagctagc tgctgacttt agctgtcagt ccttttttga cgctgtttct
     7261 cataaagaga ccttttttag ttattatttg tttacaaacg taaacaaata agctatactt
     7321 aataaaaccg tagatgaaag agaggtagca atatggatac gatatctgat gcagaatggg
     7381 aggttatgcg tgttgtttgg gctaatggga gcatgaagag ctctgagatt attgctattc
     7441 ttcatgaaaa gcaccattgg tctgattcta ccgttaagac cttgattgga cgcttggtta
     7501 agaaaaaagc cctaagggct gatagacagg gacggtccta tatttaccag tccttgcttg
     7561 atcaggacag gcgacagctt gctatgctac gagagaggct tgatggcatg tgtcaacgcc
     7621 accatagccg cttgttgctg gcattactaa aggatacccc aatgaccctg gaagatattc
     7681 aggcttttca gttgctctta gaggctaaaa aagtcggagc agtatcccat gtaaggtgtg
     7741 attgtgtgcc aggacaatgt cattgtcaga aaaaggagag gatatgattg ttaaagagac
     7801 ctatctatta gagggaatgc actgcacctc ctgtgctcta gcgattgaac aggctgttaa
     7861 gcaactgcca ggtgttgagg gggcagctgt tgatgtgacg actgagaagc tatcagtgag
     7921 ctactcaact gacagcctca gctcagcaga gctcattcaa gcagtaagaa aggcaggcta
     7981 cagagcagag ctgcttgatg agaccaatat gagagggcaa ctagagcgcc tagaggagca
     8041 ggctagcaat gaatggtatc gctttctgtg gtctgctctc tttagtctgc cgctgctata
     8101 ccttgcaatg ggacctatgc ttggattggt gctgccggtc gctctagcac ctcagtcgca
     8161 tgctataagc tatggtcttg ttcagctttt gctgaccctg cctgttcttt tcttgaatcg
     8221 gcagtactat gaaaatggct ttaaggcatt gataaagaag cggcctaata tggattcgct
     8281 tgtgacctta gccactagct ttgcttttat ttacagctca tatagctgtt ttaagattgt
     8341 agctggagct gctcaatttg ctcaccagct ttattttgaa tctgttgtgg ttattctgac
     8401 cttgattacc cttggcagct atttggaggg gcgtaccaag ggacgggcct cgcaggctat
     8461 tcagaagcta atgtccttaa gggtaactga tgtcagggtt attcgtgagg gagcacttca
     8521 gcttattccc ttagagcagg tgactaatga ggatatttgc tttattcaac cgggtgaacg
     8581 ggtggctgtt gatgggctga tagtagaggg gcagtctacg gttgatgagt ccatgctaac
     8641 aggagaaagc ctaccagttg ataaggtgac aggtgatagt gtgtttgctg gcacaatcaa
     8701 tggccaagga gcgctaaggg taaagccctc taggcttggc aatgacacct tgctttcaca
     8761 gattattgag ctggtggagc aagcacagca agccaaggct ccgattgctg cacttgctga
     8821 tagggtatca ggagtctttg tccctatcgt attaagttta tccctgctga gctttctttt
     8881 ttggctcttt gttatgagag agagctttga ttttgccctg acaatagcta tagctgtttt
     8941 gattattgct tgtccctgtg ctctgggtct agcaactccc accgcgatta tggttggctc
     9001 aggtcgtgca gctgagcagg ggatcctttt taagggagga gatattttag agaaggctta
     9061 tcaggtgcgg acaattgttt ttgataaaac aggaacgctg acagagggtc aggctcagct
     9121 acagcggatc atcccccttg ctgctagtga gaagcaggga cttcaggagg tggcttcctt
     9181 agagcagtat tcgcagcacc ctcttggaga agcgcttgtt agagtagcac aggaaaaggg
     9241 ctatgacttg ctggctgtga ctgattttca atcgcttgtg ggcttgggtg tcactggtgt
     9301 gattgaccag catcgcttag ctgttggcaa tagtgagctg atgtcacagc aggggattgc
     9361 gataagcgct gctcagacct atgccgagca agctgcctta aaggggcaaa ccgtagtgta
     9421 ttatgccaag gataatcagc tatgtgcttt attgctgatt gctgataggc taaaggctga
     9481 cagtaaggca gctataaggg ccttgcagga tttaggtctt caaacggtta tgctaacagg
     9541 agataatgcc ctcacagctc aagcgattgc taatgaggtg ggaattgatc aggtctttag
     9601 tcaggtgctg cctgctcaaa aggcccagat tatcgcggat ttgaaggcta gcggacagct
     9661 ggttgctatg gttggtgatg gaatcaacga cgcaccggcc ttgaccctag cggatattgg
     9721 aatctcaata ggctcaggta cggatattgc gattgaggcg gcagatgtta tcctgatgac
     9781 ctcagcagtg cgtgatgtgg tggaatgcct agagctcagt cgtcaaacca tcagagtggt
     9841 taagcaaaat ttattttggg cgtttagcta taatagccta atgatccccg ttgctatggg
     9901 tatccttcat gtctttggcg gccctctatt aagcccaatg ctggctggct ttgcgatgag
     9961 ccttagctca atatcagtgg tgttaaatgc tttgcgatta aggcataaaa aatggtaaag
    10021 gctctcaccg accttaccgt cagtatagta aagctaaagg cctgcgccga caaaaggcat
    10081 aaacaaaaca aagagcagga ataaaaaagc agatcattta ttggttaagg ctaccagaag
    10141 ccaccaagtg ctatagcaac ctgatatggc aaatagcacc gaaaaatatg acaggtatag
    10201 gataacctta cattatcgct gagagattta aaggtgctat tattgttacc gatcataggt
    10261 ttcttcatat tgacaccact ttttagctgt taatatgaga agacggttta agcaggcttc
    10321 gtattttggt tgagaataga ctaagtgaat tgttctatga caaagaaagg ataacaggct
    10381 ttatgagtta atagggtgtc attagctccc ggcttatttt ttgactaaca tcaacagaag
    10441 agcagtaaac caagcaaggg tttgctgttt tttcttgctc agcatgagac ggaaaaagtg
    10501 agcataacaa gcaatcaaaa agagcagctg aatcatggtc aggcaaagac agcatgcgaa
    10561 gaacaagctg aatagtgact ccaaaagaag ggctggcgct gatagtcttg atctcataga
    10621 ggcctttatg gtttccgctg ataaacgggg gtattgctca caacatgatt aggtaaaaaa
    10681 gagcacaatg atgtctatat taacattatg tggttattat tgagcgtcat ttaaatataa
    10741 taatagaaaa aatagtttaa aaatggtata atattataaa ttagctgtaa cgcaattgtc
    10801 atttataggt taagcaaaag cataaagtga ctggtgttat caagagcagc tgagcgctgc
    10861 tgatggagaa gtatctggag taagtgagat gaacgaaaat actaagcgat tgacagatcc
    10921 tattgttttg gagaagagta gagctataga agcttcgcct gagcatcacc aaaagctgga
    10981 gcaaattaaa agcgagatga gtggaaatgc tagaaagaat aatctgggct ggctggcaat
    11041 ggtgataggc gcaatcatct tgtatggcat ggttgaccga tctcttgcct tatttctcat
    11101 tatctttgtg gggggcttgg tttggccgcg gctgaaaaca ttcaaaacag caaatgagct
    11161 ctcctatgtg gatcactttt tgctgcctgt tttacaagag gccctgccag atgtcaagat
    11221 agattactat tcagggattg agctctcctt actaaagctt gcaacaccgt cctccagatg
    11281 gtatgacagt aattgccata ttatttttgg agatgacatg cagacagaat tttgcaatct
    11341 ttatgcctac catgaggaaa atgaggatga taactggcat cgggtcactg attttaacgg
    11401 acaggtgctg ctggctaaat atcatacagc tatcaagggt tatattagaa ttgtgccgac
    11461 tcaaaagggc tttttgggca gagaaaaggt ccatagtggc tacaaggcta agctaaaggg
    11521 tgaggtgcag ctggaaatgg aggacattcg ctttaatgaa acgtacaatg tgtactgcac
    11581 agatgaatta agcgctagaa tgctcttaaa tccttatatg ctggcagtgc ttgatgaatg
    11641 gagagaggag atgcctgtag cagtttatat gaatggtgat actgttgttg tgtccttcta
    11701 ttccggtcaa cagctcttga aaacccctag ctctagaggg gctattgaaa agctatcgtt
    11761 aagtagcgaa tatgaaaaca ttcaagacaa gcttgttaag atgtaccgct tgttggatac
    11821 actaaatcat cagctttaag gaggcttttt tatgtcagtg acgtcatcta tgttaacact
    11881 tattctttgc atgactatac tatggcttat tggagtgaga aacaaattag aaaggtatcg
    11941 aatcgttata gaggagtcta aacgaaatgt cgatattgct cttgagaaga gatatgatac
    12001 catttcggaa atgctaaaaa tcgctaagtc ctatgccaag catgaggaaa aggtctttac
    12061 tgaactcgtg aagctgcgtc aggggctttc cttggaggaa acaaatgatg tgatgaggac
    12121 acaggagcag gccttgaatg aggtttttgc tgtaggagag gcttatccgg aaatgcgctc
    12181 ctctgagcag tttttgagcc tgcaaaatga gattgctaag gaaaatgcag ccttggcagc
    12241 agcaaaacgc attgtcaata gtaatattag tctcttcaat caagcggtgg ttgcttttcc
    12301 ggtatcaatt gtagccagcc ttatcaatat caagcagatg acctttcttg atattgacct
    12361 tgaccataaa aagagtcttg atcagctgga ctataccatt taggctgtct gctcgttaag
    12421 aggtgaggta ggtaaatagc tgttagaaag cggctaagct gtcgtatgag ccctttcaca
    12481 gccctcagcg tagaaaaaga gtggaataac cattcaatcg tcatgacctg gcgatgttga
    12541 ttaggttatc caccctcgag cagctgatta aaaaggccac atcgcttgaa aaatgagggc
    12601 taagagccct ccaatcaact ctatagtttg acgattttaa aagaggaagg atttttgtcc
    12661 tagcctcttt ttgctttgct taacgtgtga taggttaaaa aaggcatgaa gccccattgc
    12721 aatattagtg gcttcatgcg cttttatgat gctatttcgt ttgatagctt tgtttacctg
    12781 ctggactcag ggtggaaaca gatagagagg caggctgtct agctgctgac ctgattgtca
    12841 gctggccttg cgattaagag cttggcaaat tggcggtaac gctccttaac gctgtcacta
    12901 atcttggagt cagtgataat ggcgtcgata ttgtcaaggt gataaaagct gtaaaagtca
    12961 taggcgttaa acttttggtt gtcagcgagc aggtattttt cgatggcatt gtcacaggct
    13021 aggcgctgaa taaccccttc gttttcactg taggtggcaa tgtcattttt ataaataccg
    13081 ttgcagctga tgaaggcctt ggcaaacttc aaggataaga tggtctggct tgcaaggctg
    13141 ccaacaaagg ctcctgtgat ggctcggtac tcaccaccga taagaatgag atcaacagtt
    13201 ttacttttat taagaatcgt aaaaacaggc agactgttgg taataatacg gatgtgacgg
    13261 ttgattagag cctcagccaa gcattctagt gttgtcccag ggcctataaa aatggtctca
    13321 ccatcattaa tgagctgact agcgtatctg gcaatctctt ttttagcttc aatttgtacg
    13381 gttagctttt cagtgtttga acgctccagc ttttgaggca tagaaatgct ctgggcaccg
    13441 ccacgaatac gtactaattt tccagccctt gctagctcat ctaaatttcg cctggctgtc
    13501 atatctgaaa cccttaggct ttccataata tcagtgacag tgataaagcc gttggcgttt
    13561 accttttcca taattgttaa caatctttca cgcttaagca taggccgcta ctttctctgg
    13621 tgtattgtta actcataata gcataaacag tctctttttt caataaacaa caaaataata
    13681 aaaaacaaaa caaaaataaa caattttgaa cggtaatgac aataaaagga gatcctatga
    13741 ctattatctt aggtgcagat gcacatggaa atgatctaaa agaggctatt aaaggctttt
    13801 tgcagcagga aggctttgat gtgacagatg tgacggcgat tgctgatgac tttgttgaca
    13861 atactctagc agttgctagg gcgctcaagg ctgatgagga aagtctaggc attatgattg
    13921 atgcttatgg agcagggcca tttatggtcg ctaccaaaat caaaggtatg gtcgctgcgg
    13981 aagtgtcaga tgaacgctct gcctacatga ctcgcggtca taacaatgcc cgcatgatta
    14041 ccatgggagc agaaattgtg ggtcaagaat tggctaagaa tattgctaaa ggttttgtga
    14101 ctggtcacta tgatggtggc cgtcatcaaa ttcgtgttga catgctcaat aaaatggctt
    14161 aacgaaggga ggatatcatg aaaattgcta ttggctgtga tcatattgtg actgatgaaa
    14221 aaatggctgt ttcagatttt ttgaaatcaa agggctatga agtgattgac tgtgggacct
    14281 atgaccatac ccgcacccat tacccgattt ttgggaaaag ggttggtgag gctgtcgcca
    14341 atggcctagc tgatcttggt gtctgtatct gtggcactgg tgttgggatc actaatgctg
    14401 tcaacaaggt tcctggcatt cgctcagcgc ttgttaggga tatgacaaca gcgctttatg
    14461 ccaaagaaga attgaatgcc aatgtgattg gctttggtgg taaaatcaca ggtgagcttt
    14521 tgatgtgtga tattattgag gcctttataa aggcagacta taaggaaacc gaagagaata
    14581 agaagttaat tgctaagata gcccatttgg aaagtcataa tgctaaccaa gaagatcctg
    14641 acttctttac agagtttttg gacaaatggg atcgcggtga ctaccacgat tagggagaag
    14701 cgatgatttt aacggtaacc ttaaacccat ccattgatat ttcctatcct ctaaatcgtc
    14761 tgactttgga cacggttaat cgtgttgaca gaacgacaaa aacagccggt ggtaaggggc
    14821 tgaatgtgac cagagtgtta gcagaagctg gtcagtcagt tgtggcaaca ggatttattg
    14881 gtgggaaact gggtgacttt gtcattcatc agttacaaga acagggcatt tctaaccaat
    14941 tcttcaaaat caaaggggaa acgagaaatt gtattgctgt tttacatgaa ggcatgcaga
    15001 cggaaattct ggaagctggt ccctacattg atatggacga ggccgaaggc tttttgaacc
    15061 acatgagtat tattgctaag cagtttgatg tcttaacctt ttcaggcagt ctgcctaagg
    15121 gtctggccgc tcactattat caagacttga ttactatggc gagagtctat ggcagcaaag
    15181 tggttttaga ttgctctggt gctcctttaa aagcggtact ggctggcaaa gataaaccaa
    15241 ctgttatcaa acccaatttg gaagaattgg aggatttgat aggccaacct gtcacattag
    15301 atgaggaacg tttaatctct ctgttgagtc aacctttatt tgaagggata gaatggatta
    15361 ttgtttctct tggtgcccaa ggggcctttg ccaaacatca taacaggttt taccgtgtta
    15421 ccattcctaa aattgaggta gtcaatcctg ttggatctgg tgacgctact gtggcaggga
    15481 ttgcttgggc tttggcagaa ggagatgacg atgagacgct tctgaaaaaa gccaatgttt
    15541 taggcatgtt aaatgcgcaa gaaacaagaa caggtcatgt taacatggca cattttgatg
    15601 agctatttga ccgtattcaa gtagaggagg tataagatga cattaacaag aaacaaaaaa
    15661 gcttatttag aaaaggtcag tcgtaaggga atcatttcgg ccttggcctt tgatcaacgc
    15721 ggggctttaa agcgcatgat ggcagcccac caagacacag agccagctcc ttggcaaatc
    15781 gaagccctaa aggctctggt atcagaggag ctaaccccct atgcctcctc tatcctgcta
    15841 gaccctgaat atggcctgcc agccactaag gtacgtgatg agaagtctgg cttattatta
    15901 gccatggtga gaccgaaatc attcataatg gcaagggaga aaaaggcggc tccaaatatc
    15961 agataaaggg ggttggtcaa cgcgtgtttg atgttgatgt gccgcgtaca gactgggatt
    16021 ggatgatcta tccacagggg ctttacgatc aaatcatgcg gatcaaggca gactatccag
    16081 gctataaaaa gatttatatc actgaaaatg accttggcta caaggatacc tgtattgatg
    16141 gcaggattga tgatgacgct agaattgatt acatcaagca gcatttggct gtgattgcag
    16201 acgctatcgg tgctggggct aatgttaagg gctattttat ctggtccttg atggacgtct
    16261 tttcttggtc aaatggctat gataagcgtt atggcctctt ctatgttgat tttgaaaccc
    16321 aaaagcgtta ccctaaaaaa agcgcttatt ggtatcagca gctagctacc acaaaaacta
    16381 tttcagtgta atctcctaac gaaaagcacc ggcacaaggg ctgcaaggct tcaagagctg
    16441 gtgcttttct tttttatgct atactggtaa cgatgaggtc atgacataaa gagataacaa
    16501 gtgggttgta gcaacctcgt attagctgcc agctgctgat aatctcattt ggtgatgatg
    16561 gagagtacca gcttgaatga ctcattaaaa aggaggttat gatgaaaaaa gtaatgatgt
    16621 ctttgctaat ccttgctacg gcaactcttg gggcttgcca ggcttctcac cagtctgatc
    16681 agcccaagca ggagcaaaaa gagccacagg ctaagaaggg acgtcttttc ctatccaaca
    16741 tgaacagtgc aaagagccag caggaggtca gggctgccct atcacatcag ctgaaggaag
    16801 ctaatgtcaa tgcctttatg gctggtgtac aagaatataa tagcctagtt ggcaaaacag
    16861 gcttgacagg ggcctttacc tatcagaagc agcctgacta tgatgtggta gcaatcgatg
    16921 agttgtggtc gcaaaagcaa ggcaatttca ttggaactaa ttgccggatc aacaccttta
    16981 tgcttctaaa ggatagcatg acgattgcgc ctaccagcag tgatgatacg cttttattta
    17041 tggacgagga cgccattacc acaagccagc tctttacaca ggcagagaca gagcgcttta
    17101 agcagctgtt ttcaagagtg aaaacggaag ccaccaagga tattcaggtg catgccaagc
    17161 atatgcaaga gcatttctca gctgttagct ttaatggccc agccaaaatg cttgctgttg
    17221 tgattcacga tcagctagat ggtgattacc tttttattgg tcatgtggga gtgctagtgg
    17281 agtataagag caagtatctg tttgttgaga aattgtcctt ccaagagccc taccaagcca
    17341 tcctctttga tcaaaaacag gattgctacc aatacctcta ccataaatac aagacctatc
    17401 aaaccaagac atcagcagag ccctttctca tggaaaataa caaggctgtg aatttggcaa
    17461 gctatcgctc ctaactcctg ctactaggag cctagcctat ataggggcta aatctttggt
    17521 gcaaacaaaa acaggtcatc agtaggattt ttgaggacct tgctcttatt ttgacttata
    17581 ttttgattaa aaagatggta gactaatagg ggattaggaa gcattaggtg agttatgaca
    17641 attgatatgt gggagctttt aagcattatt ggaacgatag cctttgcctt gtccggcgct
    17701 attgtcgcta tggaggagga gtttgatgtt ctggggattt ttattctagg ctttgtcaca
    17761 gcctttggtg gtggggctat tagaaatacc ctgatcgggc tgcctattga agccttgtgg
    17821 ggacaaagac cagaatttgc ctgcgctttt atagctatta ttctgatcat gctatttcct
    17881 aagcttgtgg ctaagggctg ggtgagagca gcggtgctga ctgatgctat cggacttgca
    17941 gcctttagtg ttcagggggc tctacatgct gttcgactag cccagccctt aagcgctgtt
    18001 attgtagcag cggttcttac aggggcaggc ggaggtgtgg tcagagatgt cctggcaggc
    18061 cgtaagccaa ctgttcttag aagtgagatt tatgctggct ggtctattat agcagcactt
    18121 gtgctttatt ttaagctggc cacttcaaat gttgaatgct acttgctggt tgttttattg
    18181 acagtcatgc gtatgattgg caacaaaaga caatggcacc tacctaagat aaaatggaaa
    18241 gaggactgag acgatgattc agcttatagc aattgattta gacggtactc tgcttgatag
    18301 caaaaagcac attccaaaag agaatattaa ggctatccaa gcagctgcac aagaggggat
    18361 aaaagttgtt ctctgcacag gccgccccca gtctgggaca aggccgtatt ttgagcaatt
    18421 aggcttgagt gataaggagg agtaccttat tttaaacaat ggctgtagca cctataggag
    18481 cccaagctgg gagctgctac attatcaaag cctgaccttt tcagctattg agcaccttta
    18541 tcagctgtct cagccctttt cagatattta cctcaccctg actggagagc gtgattatct
    18601 tgtgatagat agcaaggttc cagatatggt tcaggctgat ggtgatttgg tttttacaaa
    18661 ggtaaaggct actaacctat ctcagttatc caacagcagt caaatcatat ttcaggccat
    18721 gtacatggga gaaaaggctg ccctagatac ttttgaggct cttgttagag aaaaactcag
    18781 cgcaagcttt agtgtggttc gcagtcaaga aacaatccta gaggtaatgc cggagtgtgt
    18841 gaccaaggcc tctgccctga aggaattaac cgctgatctg aagctgcgcc cagaccaagt
    18901 gatggcaatt ggagatgcag caaatgatct tgaaatgtta gcctatgctg gcttaggtgt
    18961 cgctatggga aacgctgatg aggcaattaa aaaggtcgct gacaaggtaa gcctctccaa
    19021 tgatcaagca ggcgtggccc atgccattaa tcaatttgca ttgacaaagg gctcttaagc
    19081 acagtcaaac cagcccgtca gaaaaggcct ccaaaagcta gagatgataa gctcagtttt
    19141 agaggtgttg actagagctg agctgtcttg gaacaccaca agcctaggtg tgtgagatcg
    19201 actgaaaaat aaaacacgaa aaaacctcca acaaaggagg ttctggattg aagagcaggc
    19261 taatccagcc agcctcttca gtcttttttt attgtccagc taaatgtaag agcctttaag
    19321 cctctgcaca acagcgagcg acaagtcaca ccttgcctgt agtagggcta gtacatatct
    19381 tggtaggcag tgccagtgct taagtcaagc cagccaagcg tcctgtctga tgctgcaagc
    19441 ttggtttctt gggaagttgt ctaggagcta taggtgatct agagacaact aggctaataa
    19501 gggcagcccc atagcagcca tctcctcagc aggaacaacc atatcatcag aaatccaatt
    19561 ggaaaggact gagacaatag cgttgctcca aaagagcagt gcgtagtgag acagcttttt
    19621 ttcctgccac ttttggtagg ctctcaaacg cttggtaacc atctgcgtca agagctgctg
    19681 caggtgatgg ttaaagataa tactaagtag cgtcgcttct tttttggcct ctgtaaacag
    19741 ataaagccat gcctgatagg cctgtgtctt tagatcaaag gccttcagtc cacgaaagat
    19801 acgtctgata acagaagtca acagacactc aagaatatcc tcctttgagc tgtaattgcg
    19861 gtaaaaagca tttcttgaaa ccccagctct agctaccaat tctgaaatgg taatgtgtcc
    19921 taagggcttc ttttctagta agctaagcag agcaatttca atagcttctc gtgttaaccg
    19981 tctggattcc tgattgcagt gggctaaatt ttgaagggac tgtttagaaa ttggtttacc
    20041 agccattaca aatacctttc aagtgttaca tctgatgtcg tttagctagc aaaagtctag
    20101 ctagtgatga tataatttta tgggaaaatg cttactttgt caaccaaaac agactatgaa
    20161 ggaaaagagg aaaacgaatg acctggaaaa ttgtatcgga ttcaggctgc gatattagag
    20221 ccctaaaaag ccaatccaat cacctgcgct ttgagcgtgt gccgctaacc ctacagattg
    20281 gttcagatat ttttagagat gatgatggtc tagatattga tcaaatgatg gagactatgt
    20341 atcagtcctc taagccagca acctcaagct gcccaagtcc tgatgctttt ttacaagcct
    20401 acaggggagc agataacgtc attgccatta ccattaccgg tacgctctca ggcagtcaca
    20461 atagtgctag attggctcaa aatgacttgc ttgaggaaaa tccgaatgcc aatatccatg
    20521 tgattgactc tttgtcagca ggtggtgaga tggatttgat tgtgttagag ctagagcggt
    20581 tgatcaatca ggggctttct tttgatgagg ttgttgagaa aattacagct tatcaggaaa
    20641 aaaccaggct tgtttttgtg ttggccaagg ttgataatct ggttaaaaat ggccgtctga
    20701 ataagctcat tggtaaggtg attggcttat taaacatcag aatggtagga caggcaagta
    20761 aggaaggcac gcttgagctg cttcaaaagg ccagaggtca aaaaaaggca gtgtcagctg
    20821 ttttagaaga gattcaaaag gcaggctata aaggaggccg agtctttatc tcccacgcca
    20881 aaaaccctaa gatctgtgag caaattgcgg aaaaaattag agcgatttac ccagaagcag
    20941 agattcaaac cagcccagcc tcaggcctat gcagcttcta tgcagaagct gaagggcttc
    21001 tcatgggcta tgaggtttaa gctaagcaaa gtgatctaac gctgcctctg gtttctgtta
    21061 gtcatagagg ctgagctatg cacagcttga ctctagctag tggtcggata ggcataggtc
    21121 tttatcacaa gtctttagct gagagctgcc ttaacaaata tccctgatac tatagaggca
    21181 ttaagctgaa tacaaggtcc ttaaaggtgt gtttaagggc tttttgttgt gcatgctaat
    21241 cacctcgtca gtcccttaaa agtcttaggg agtgacactg aggaaaaaac tcaaatggtc
    21301 aagccagtca gaatatccat gacgaatcac caaagcgcgt aagggtgagc cgctctataa
    21361 tcatagccaa gctgatagag agttaggaga ggatatggga ttacttatcg acttgattaa
    21421 gcctcccttc tcttcctacc tcaaaatcaa ttaagaagca caaaaacagc tggaatcctt
    21481 ttagaaccag ctgtttttaa tcacctaaag cctcttttta tcagagagct tattagtcgt
    21541 aagtttagca ttatttcagt agctaagccc ttattgcctg tactaagaag tgtaactaag
    21601 ctacagcagc tctggctgcc ctttcttagt tttgtcctgc tggagcagtg ttttcacttt
    21661 gctctgttgc aggtggctga gggctaggtg tgttggtttc tggttgagga tttggctgag
    21721 ggttaggact aggcgttggc tctgggttct ctggagctgg actaggacta ggctgaggat
    21781 tcggcttagg actaggttta gggttcggtg ctggcgtcgt tcccccagaa gacggtgtgg
    21841 tatgctttat ttgtggagcc gcaggagctg gtgctatatt tttttctgct gctggtgttg
    21901 cagtctcagg ctgtgcagtg ctaggctttg aaagtccaat agcgtcaagt ctagcctgta
    21961 aggcagcttt tttagcctca tcagagagct tactaatggc tttttgtgca gcctccttaa
    22021 gttcagggct tggattgtcc tcggctgcct ttaggacctt gatagcaacg tcttcttgat
    22081 tgtgctttaa gctgatagct gttagtcgag cctgtaattc ctccttagac tgggtctttt
    22141 ttagctgatt aattgctttt tgagcctttg cgatagcttc tttagttggg ttgtcttcgg
    22201 cctccttgac taatgcttga gccttagtta acagctcata gcccttagat tgggtggtaa
    22261 tggtagctgg ctttggagag aggctactaa aaataaggta ggcccctcct gcaatggcaa
    22321 tagtaagcaa gctaatgatg aggtagtggg tctcttttgt cggttttctc atggtatctc
    22381 ctttgaaatc attgtcgctt gagtagcact attataccct gaatatagga aaatgaaaag
    22441 aggactaggg ctctaaaata ggttctaaat gagcactatt taaaaggatt aaaaaaccct
    22501 tgtgataact gaataaatac attaaaatag aagagaataa ataagcgagt gaggacaata
    22561 ttgtgtcggt aaattggcaa gacattgcgt ttcatttttt ggggggcagt acagggctta
    22621 ggtctttttc ttttcagtat caaatacatg ggagacgact tgcagcaggc cgcaggtgat
    22681 aagcttaggt attacattga caagtacaca agcaacccct tctttggtat cttggttgga
    22741 atagctatgt ctgctttgat tcagtctagc tcgggtgtga cggtgattac agttggccta
    22801 gtatctgcag gccttttaac cctacagcag gcgattggta ttgtcatggg ggccaacatt
    22861 ggaacaacag tgacctcctt tttgattggt tttaagctgg gagattacgc cctgcccatg
    22921 atttttattg gagcagcctg tctctttttc acgtcaaata aaaaactcaa taacctaggt
    22981 cgtatcattt ttggtgtagg aggaattttc ttttctctca acctcatggg tgatgcgatg
    23041 gatcctttaa aatcagtctc agcctttcag cattacctag cgacgcttgg agacaagccc
    23101 tttcagggtg tttttatcgg gacagcattg accatgctga ttcaatcctc ggcggccatt
    23161 attggtattt tacaggggct tttttcgggt ggcctattga ccctgcaggg tgcgattcct
    23221 attttgcttg gctctaacat tggtacctgt atcacagcgg ttttggcagc tattggctct
    23281 aatattgcag ctaagcgtgt tgctgctgct catattcttt ttaatgttat tgggacggtc
    23341 atctttatga ttttactgat gccatttacc tcctttatgc tatggcttca gtctgttttg
    23401 gccctgtcac ctgagatgac cattgccttt tcacatggga cctttaacat cacaaatacc
    23461 ctgttgctgc ttccttttat caacactctg gcaaagcttg tgaccacctt aattccaggt
    23521 gaagacgaaa tcgtcaaata tgaagccttg tatttggacc gtttactaat cactcaggct
    23581 ccttctattg ccttgggaaa tgcccacaag gaattggtac atctggcttc ctatgctatt
    23641 caggcttttg aggcgtctta tagctacatt atgacagcag aagacaagtt tggcgaaaag
    23701 gtgaggcgat atgagaaggc ggtcaatacg attgatgagg agctcaccac ttacctcgtt
    23761 gatatttcca atgaagccct tagtcctagt gaaaatgagg ttttagcagg tctgttggat
    23821 tcgtctcgtg atttggagcg aattggtgac cactctgagt cgttagcgac tctcattgag
    23881 gggattacag caaagcagat tggcttttca gcagctgcac gtggtgaatt aacagaaatg
    23941 tatcacctga cccactgttt aactttagat gcgattaggg cgattgtgga tagtgacaag
    24001 gctctagccc agtctattgt tgagcgtcat aggacgattg agcaaaaaga gcgtcaattg
    24061 cgtaaaacac acatcgaacg cctcaatcgt ggcgaatgca cagcacaggc agggattaat
    24121 tttattgaca ttatatctca ttacacacgt atcactgacc acgccctaaa tctagctgag
    24181 aaagtacttt caggacagct ctaataaaag ggaaaacttg aaatagtatt caggtttttc
    24241 tttttaacag aaggactggt atataccatt tacaaaataa gaattaaggc gtataataaa
    24301 cgaaaaaggg aggaaaaaag atgacaagct atattaaagc agattgcttt tattacccca
    24361 acgaggtaaa gccagcaggc tatttggagc taaataatgg cacatttggt tattggacgg
    24421 ctactgttga tgatcaggca gaggttattg attatacagg ctatcaaata gcaccaggac
    24481 ttgtagatac tcatattcat ggctatgctg gtgctgatgt gatggataat tcagcagaag
    24541 gtctccatgc catcagtgag ggtctcttat caacaggagt gacctccttc ttaccgacta
    24601 ccctaacgtc aacctttgag catctagagc aggtgtctgc aaccgttgct tctgttgccg
    24661 atcaggtcaa aggagcaaag attcagggga tttattttga agggccttac ttcactgagg
    24721 aatacaaggg agcccaaaac ccgatatata tgaaaaatcc tcgcttagac gaatttgcag
    24781 cttggcaaaa agcagctaag ggcttgatca aaaaaatagc tttggctcct gagcgtgatg
    24841 gcgtagaagc atttgtctct gaggtgacca agcagggtgt cacagtagct ttaggtcact
    24901 caaatggtac ctatactgag gctaaaaagg cagtagcagc aggagctagt gtttgggttc
    24961 atgcctacaa tgggatgcgt ggcttgactc atcgtgagcc tggtatggtt ggggctgttt
    25021 ataatattcc tggaacggtt gcagagctga tctgcgatgg tcatcatgtc tcacctgttg
    25081 cttgcgatat tttgatgcag caaaagggtc atgagcatgt ggctttgatt acggactgta
    25141 tgcgtgcagg cggttcacca gatggtgatt acatgcttgg agagtttccg gttattgtgg
    25201 aaaatggcac agctcgcttg aaggatagtg gtaatctagc aggctctatc ttaaaattaa
    25261 aggacggcat taaaaatgtt gttgcctggg gaattgcaag tccagcagaa gcaattcaca
    25321 tgtcctctta cgtcccagct gcttcggttg gtattgaaga tgtctgtggc caaatcaagg
    25381 caggtcatgc tgctgacttt attgttcttg ataaggactt agaattagta gcaacctacc
    25441 taaatggtca aaaggccttt gaggcttaat acagcaaagg aattgggctg gtgatcagct
    25501 caattctttt tgctttgctt atcattgtgc tacaatgaaa aaggaggttt tagatatgat
    25561 taaaacagta acaatggcta atggtcttgc tattccagtg cttggctttg ggacctttaa
    25621 ggctgctgat ggtgaggagg cctaccaatc caccctagca gcgattaagg caggctatcg
    25681 tcatattgac acagctgcca tttatcacaa tgaaaaaagt gttggacagg ccattcggga
    25741 ttcgggcgtt cctcgtgaag aactctttat taccactaag ctctggaatg atgctcatag
    25801 ctatgatggc gctaaggcag ccttagcagc ctctcttgag cgccttggac tagagtatgt
    25861 agacctttat ctgattcatt ggccaaatcc taaggctctt agggattgct ggcaagcagc
    25921 caatgcagca gcttggtctt atatggagga ggctgttgaa gcaggcttgg ttcgctcgat
    25981 tggtgtcagc aactttatgg ttcaccatct ggaggctctt aaacagacag caaccattac
    26041 accagcagtc aatcagattc gcttggcgcc tggctgctat caaaaagaga cggttgatta
    26101 ttgccgcagg catcacattt tgctagaggc ctggggtcca ttaggacaag gagagatatt
    26161 tgccgatgat accatgcagg cattggctaa aaagtacaac aagacagtgg ctcagctagc
    26221 ccttgcttgg tctattgctg agggctttat tcctctacct aagtcggtgc acaaggaacg
    26281 catagtagaa aatatggcta tttttgattg tgagattagt ccagaggatt cagagcgcat
    26341 tcgttgcctg ccgggtatgt cagctatccc agatcctgat accaaggact tttagcaaga
    26401 gctgcaggga ttaagtgagc tacattagtg gtccttgctc gtgctttggt caaaacaccg
    26461 cagctgttat tggcagatga gccaacaggc gccctggata ttgaggctga gcaggaggtc
    26521 ttacaagcca tcagagcttg tcagactgag gatatgattg tcttaatggc aacacacagc
    26581 gatgaggttg cagcgcaatg tgacgctatt taccatattg aggatttgtg tttacgacag
    26641 gcgaagtagg tcaggcctgc aaaatgcctc ttgggtgctg cttgctgctc gtgaattgac
    26701 tgagtctagg agctgtcttt tgatggtgat ttggtacgac cttaaagctt tgatgaggtc
    26761 tcttgatggt gctgtgtgac gacctcttgt ttttagagat caaagaaaga catctttttt
    26821 ttgaaaacgg tttgacaagg ctgtgtaact tagctataat cttaattagt gtttcgtgaa
    26881 agaaacagat taaactagaa taaaggagtc ttactttgat tatcctgtta ttgatgctct
    26941 tgatgtttgc tattcgttta gtattcttaa aaaaatcgat caaaaacgag aaggctatcc
    27001 tggctaatgg gggcaaggaa tttggtgcgc aaaacactaa gtttttgacc ctgctgcata
    27061 tcatgattta tgtctttgct gtgacagagg cattgctcaa gcagattaag tttgatggca
    27121 ttagctttct tggcttgctg ctgatgattt tttcgatagc tgtgctatat gaggtaactc
    27181 ggatcttggg agatatttgg acagtgaagc tgatgctggc aaaggaccat aaatatgtcg
    27241 atcattggct ctttaagact gttaagcacc ccaattactt tttaaacatt gctccagagc
    27301 tggttggtat tgctttgctt tgccatgctc agattacggc aatgctgctt ttcccttgct
    27361 atattattgt gatttatctg cgcattcgtg aagaaaatag gctcttgtct gaggttatta
    27421 ttccaaacgg aactcgtcca aaatcataat agttgattag acaatcatag gattttgtga
    27481 taaactaacc aataggaaag aaaatagcag gtttctgatc taaagcgagc tcggggctgg
    27541 tgagagccga gtgatggtac tgctggttgg cgctttctct aaagagtagg ctcaggtgtt
    27601 tgtagcttgc ttgacatctg tttatcaaca agatcaaatg aagtaataaa ttagggtgga
    27661 accgcgtttt gacgccccta tgcctttagg tgtaggtggc tataggcgcg gtttttctct
    27721 ttgaaaagct gtttaagagc caaccagcag tcaagccata gccagctctt ggttagcgcc
    27781 tgcgacaaga cataaaaaat agaaagagga aatcatgagt aacaaactta cctttcaaga
    27841 gattattttg acgctacagc aatattggaa tgatcaaggt tgtatgctaa tgcaagccta
    27901 tgacaatgaa aaaggagcgg gaaccatgag tccttatacc ttccttcgcg ctattggtcc
    27961 agagccttgg aatgctgcct atgtggagcc atctcgtcgt cctgctgacg gccgatacgg
    28021 cgaaaatccc aatcgtctgt atcagcacca tcaatttcaa gtggtgatga agccttctcc
    28081 aagtaatatt caggagcttt acctgcaatc tcttgaaaga cttggcattg atccattgga
    28141 gcatgatatt cgatttgttg aggacaactg ggaaaatcct tcaaccggct cagctggact
    28201 tggctgggag gtctggcttg atggtatgga gattacacaa tttacctact tccagcaggt
    28261 gggaggccta gcaacatcac cagtgacagc agaggtcacc tatggcttag agcgcttggc
    28321 ctcatacatt caagaggtgg attcggtcta tgatatcgaa tgggcacctg gtgttaagta
    28381 cggcgagatt tttcttcagc cagaatatga gcattccaag tattcctttg aggtatccaa
    28441 tcaggacatg ctgcttgaaa actttgagat atttgaaaaa gaagcagagc gtgctttagc
    28501 acaagggctt gtccacccag cctatgacta tgtcttgaaa tgctctcata cctttaacct
    28561 gcttgacgct cgtggtgcag tctctgtgac agagcgtgct ggctatattg ctcggattcg
    28621 tcatttagct cgtagcgttg ctaaaacctt tgttgcagag cgtaaaaagc ttggcttccc
    28681 attgttggat gatgctagcc gagtagcctt gctggcagag gactaagcag ctggatctaa
    28741 actagttcct tgtagtcaat gcagcttgta tgatcttgta agctctagtt gctgctagca
    28801 gcttacctat ctggtaggtg ctttttaaaa gcgatgagac ttaaaggcct gatgactagt
    28861 cctgttaagc tcagtctttc tgctaagtga tcttgtctaa caggcagctt attagcaggc
    28921 ttgcaggatt aggagctagt gatttggtct cctaaaccta ccccataact tgaagaaagg
    28981 aaagaaagat gggacaaatc ttgtagacaa aggatcgtcc aagcttgccc aaggcatgct
    29041 aggatcggtt tggtcttctc ttttagattt gatgcccata ggattttaat gatgacaaaa
    29101 gatttacttg tagaacttgg tcttgaagag cttcctgcct acgttgtcac acctagtgaa
    29161 aagcagcttg ttgaacgtat ggctgatttt cttaaggcca atcggcttag ctatgacgca
    29221 atcgaaggct tttcaacgcc ccgtcgttta gcagtgcgtg tgctgggctt agctgatcag
    29281 cagactgatc tgacagagga ttttaaggga ccctctaaaa aaattgctct tgacgcagat
    29341 ggtcaatttt caaaagccgc tcagggcttt gttcgtggaa agggcttgac tgttgatgac
    29401 atcgaattcc gagaggtcaa aggtgaggaa tacgtttatg tcaccaagca tgaagcgggc
    29461 aagcaggcta aggacgtctt agcagcggtg ccagaggttc ttgcttcctt gaccttccca
    29521 gtcagcatgc actgggctaa caatagcttt gactatattc gtccggtgca tagcttgatt
    29581 gtactgttag atgatgagcc tttggagctt gactttttag acattcattc gggacgtatc
    29641 agtcgcggac atcgcttcct tggagaagag actagcatta caagtgctga ttcctatgag
    29701 gctgacctgc gcagccaatt tgtcattgcc tctgctaagg agcgtcaaga gatgatcata
    29761 gcacaaatca gagccatcga agcagagcaa aaggttcagg tggatattga tgaggacctc
    29821 ttaaatgagg tgctcaacct agtagaatac ccaactgcct tcatgggaag ttttgatccc
    29881 aagtacctgg aaatcccaga agaggttcta gtaacctcaa tgaagaacca tcagcgttat
    29941 tttgtcgtgc gtgatcaggc tggcaagcta atgccgaatt ttatttctgt tcgtaacggt
    30001 aatgctaagc atcttcaaaa tgtgattaag ggcaatgaaa aggtgcttgt tgctcgtctt
    30061 gaagatggag aatttttctg gcgtgaggat caaaagttat ctattgaaga tttggttgct
    30121 aagctagctc atgtgacctt ccatgaaaag ataggctctg tggctgagca tatggagcgg
    30181 accaaggtta ttgcagcctt tcttgctgac caggctgggc tctcagaagc agaaaaaagt
    30241 gctgtcgctc gtgctgccca gatttataaa tttgaccttc taactggtat ggttggggaa
    30301 tttgatgagt tgcagggcat tatgggggag aaatacgccc ttttaactgg cgaagctgct
    30361 gctgtcgcaa cagcaattcg tgagcattat ttgccaaatt cggcagaagg agagctgcct
    30421 gaaacaaagg ttggtgctgt ccttgctctt gctgataagc tagacaccct gctgtccttt
    30481 ttctctgttg gtttgatacc gtcaggctca aatgaccctt atgccctacg tcgtgcaact
    30541 caggggatcg tccgaattct tgagcatttc ggctggagca ttcctatgga taagctgatt
    30601 gatagcctat atgagctgtc atttgatagc ttgacctatc agcataaggc tgaggtgctg
    30661 gactttattt gtgcacgtgt ggataaaatg atgggctcag ccattccaaa ggatatacgt
    30721 gaagcagttc tggctagctc aagctttgtt gtaccagaac tgttagcaag agcggaggct
    30781 ctggctgcgg caagccagct agacacctac aagcctgctg tcgagtcgct gtctcgcgtc
    30841 tttaatctag cgaaaaaggc agttgacgct gtgctgattg atgctagcct ctttgaaaat
    30901 gactacgaaa gggctttggc acaggctgtt gattcactag tgctatctgg atcagccaaa
    30961 gaacagctag ctcaggtctt tgcccttagt ccagttattg atgacttttt tgaccatacg
    31021 atggtcatga cagaggacga agctattaga cgtaaccgtt tagcgctgtt agcagagctg
    31081 gttaaaaagg tagagaccat tgcggccttt gaccgattaa atactaaata attcgctgtg
    31141 taagattaag cacatcgccc tgtgttagct gttcgtattc cctagatgat ataggtgact
    31201 gattacctgc cttgggataa gtccttccct aagcactcaa gacttatcaa gcaattgata
    31261 cttagtcaaa tcagtcctct tgcttactac gagatatcgt cttgggctag ctttgctagc
    31321 aatagctgtg ctggtcagtg gtcaataaaa gcatcaggaa cactgttagt aaagtgagca
    31381 tggattttag cttttcacaa gaagcttgct acagccttct tggcagaagc ataaggctaa
    31441 gcagctgctg gcacagcctt agatatagac aaaaagagtg cagtactcta tgtcacaaac
    31501 gaaagagaaa ggattagagg cagccccatt tgcaggcagc ccttgctggc acagctggtg
    31561 aaaaaggact tgaaaggtcc tagtaacggt cctaaagagg ctgtctagcc catcatcaag
    31621 cctcatcagc tgctcactgc ttttggtgca gcccttatat gtgatttatg gatcctaaaa
    31681 aaatcgctcg tattaacgag cttgcaaaaa agaaaaaaac agttggcttg actggtcctg
    31741 aaaaggtaga gcaggccaag ctgcgtgagg aatacattga gggctatcgc cgctcagtgc
    31801 gccatcacat tgaaggcatt aagattgttg atgaagacgg aaacgatgtt actcctgaga
    31861 aattaagaca ggtgcagcgc gaaaaaggtc tgcatggacg gtcacttgat gatccggaat
    31921 cttgattatt aaatgaatat aaatattttg ccatgattta atgttactaa tgagaaaaag
    31981 ataaacaaag acaaatagct ttaatcatta ggtctttcga caaaagagtc attattttta
    32041 gaaatggtta attgtgaggt actagccatc tgtctcatca atacagttta ggtagagata
    32101 ataatatctc taccta
//
LOCUS       DARYXW010000011        31395 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.011, whole genome shotgun sequence.
ACCESSION   DARYXW010000011 DARYXW010000000
VERSION     DARYXW010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31395)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31395)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31395
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.011"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            <1..174
                     /locus_tag="TV191_000432"
     CDS             <1..174
                     /locus_tag="TV191_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1506978.1"
                     /translation="EAKKPEQPKPMTKPGAKKPEQSLPSTGDIRNPFFTPAAIAIMIA
                     AGTIAIPKRKEED"
     gene            complement(420..734)
                     /gene="trxA"
                     /locus_tag="TV191_000433"
     CDS             complement(420..734)
                     /gene="trxA"
                     /locus_tag="TV191_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEL1506979.1"
                     /translation="MAHIVTDATFEAETNEGLVLVDFWATWCGPCLMQAPILDQLAAE
                     IDEAELKIVKLDVDDNPNTAQQFGIMSIPTLLFKKDGKVVKQVAGVHTKDQIKAIVAE
                     LS"
     gene            914..2233
                     /locus_tag="TV191_000434"
     CDS             914..2233
                     /locus_tag="TV191_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEL1506980.1"
                     /translation="MEAYELIVIGFGKAGKTLAAKMAQLGKRVALIEQSPTMYGGTCI
                     NIGCIPTKALITAAEHNASFADAMAHKDTVVHRLRQKNEQLLAQSGVTLYNGKASFVS
                     NKTIQVEAGQERILLEGKHIVINTGAVSNRFPIPGLADSQHVVDSTGILALTEQPQRL
                     AIIGAGNIGLEVASLYASLGSEVTMYEAAPAILGRYEPVVAELAQDYLEKAGVTFKLS
                     ATVELIANDEAGRVLVTANGKTEAFDCLLYAMGRKPATQGLGLENTDIKLDDRYAVVV
                     DDYCQTTVEGLYAVGDVNGGPQFTYTSLDDFRIVFGQLTGTSQYNHKDRGYLPTTVFI
                     EPPLSQIGLTEKEAKEQGLPYKANELLVANMPRAHVNNDLRGIFKVIVNTETNEILGA
                     TLFANNSHEYINLIKMAMDNQIPYTYLKNQLFTHPSMAENLNDVFNL"
     gene            complement(2573..4909)
                     /locus_tag="TV191_000435"
     CDS             complement(2573..4909)
                     /locus_tag="TV191_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEL1506981.1"
                     /translation="MEKKILEQLEFEKVKEQFWPYLQTEQGQLELDLLEPIANKDKIQ
                     AYFTELEEMAAIFVEHHHFALGGLSDVSESMQRLDLEADLSIQELLAVKKLLQVSAEV
                     CRFYADLENVDLVALKALFEKIESFPSLQGSLQAINDAGFVEGFASPELESIRRQISN
                     KEHASRQLLQDILKKQAAYLSESLIASRNGRSVLPVKNTYRHKVAGVVHDMSASGSTV
                     YIEPRALVSLNEELTQLQTDERHEIGRILHELSEQLRPHSRSLRNNAWLLGHLDLVRA
                     KYLYMQAKQATVPVISDDKSLQLLNARHPLIQNPVANDLHFANDLAVIVITGPNTGGK
                     TIMLKTLGLAQVMAQSGLPILADKGSRVAVFNGIYADIGDEQSIEQSLSTFSSHMTHI
                     VEILNQADSDSLILFDELGAGTDPQEGASLAMAILEQLRLTNIKTMATTHYPELKAYG
                     IEIAYVENASMAFDNVSLKPTYRFMQGVPGRSNAFDIARRLGLAEHIVKEAQAMTATD
                     HDVNRIIEQLEQQTLESRKRLEHIKEVEQDNLKFNRAVKKLYNEFSHAKDKELEKAAL
                     EAREIVDIALAESDSILSQLHEKAELKPHEIIEAKHRLKQLAPEQSLSQNKVLKKAKK
                     WRAPRVGDDIIVTAYGQRGTLLAQLKDKRWEAQVGLIKLTLKEDEFSLVKLKEEAQQP
                     KKRAVKVVKKAATGKGPRARLDLRGKRYEEAMQELDAFIDQALLNNMSQVDIIHGIGT
                     GVIREAVGKYLRRNKHVKSFGYAPQNAGGSGCTIANLG"
     gene            complement(4982..5527)
                     /locus_tag="TV191_000436"
     CDS             complement(4982..5527)
                     /locus_tag="TV191_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEL1506982.1"
                     /translation="MLSVLILLLLSWSFYIGYNRGLILQTFYCFGALVSLLFAHHGYK
                     ALAGKLALWVPYSNPAEGAATLFFKDINIFELDKVYYAGIAFFILSTVGYAVVRLAGV
                     LVHLAPVDYFDGFEAKLASGLLAVMVSVLFLSMALTVLATIPMPFIQGRLHGSLLSRL
                     LVEHCPFISSILRQLWVTAIL"
     gene            complement(5527..5838)
                     /locus_tag="TV191_000437"
     CDS             complement(5527..5838)
                     /locus_tag="TV191_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1506983.1"
                     /translation="MKNINRYKLTFGEKTLTLTTDKDNLFMEEVDRVAKEKYQAIKER
                     LPEADDETVAILMTINTLSAQLSREIEIEKIEAEIVELREKALAGIQEKASQADTDEV
                     S"
     gene            5956..6864
                     /locus_tag="TV191_000438"
     CDS             5956..6864
                     /locus_tag="TV191_000438"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEL1506984.1"
                     /translation="MDTLVFKINSQVSSSLIKQLAPYRISNANPYVRLAAKKDGVTLM
                     LYTSGKLVLQGRQAAKLAQELDLQETPADQRPAPSSAQDIPLIGSDEVGNGSYFGGIA
                     VVASFVQPEEHALLRQLGVDDSKNLNDKSIAQIAPVLKKHIQHRALLLSPKKYNEMVG
                     KGKPYNAVSVKVALHNQAIFLLLNDGARPEKIVIDAFTSQANYDKYLQQEKNHFRNPL
                     TFEEKAEGKYLAVAVSSIIARQLFLDNLDKLSQDLGYRLPSGAGRPSDQIASQILAAY
                     GMAGLEHCAKLHFANTKKAQALLKKQ"
     gene            6889..7488
                     /gene="lepB"
                     /locus_tag="TV191_000439"
     CDS             6889..7488
                     /gene="lepB"
                     /locus_tag="TV191_000439"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEL1506985.1"
                     /translation="MKQFIKEWGAFTLFILLFGLSRLFLWQPVKVDGHSMDPTLAHGE
                     RLIIFNKAKIDRFDIVVASEEDENGQRKEIVKRVVGMPGDKLSYRNDTLYINNKKTKE
                     PYLDTYLTSFKKDKLQSTYAYSDLFQELAENAAAFTVNSEGKTEFDITVPKGEYFLLG
                     DDRIVSRDSREVGSFKKQDIVGEVKFRFWPLNKINLFPR"
     gene            7717..10116
                     /locus_tag="TV191_000440"
     CDS             7717..10116
                     /locus_tag="TV191_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEL1506986.1"
                     /translation="MEHFFTGTVDRIIFDNASNFFKILLLAIEDTDSDFDEADIVITG
                     TMAEIIEGEAYTFWGELTQHPRYGQQLRLSRYQKAKPTSAGLVSYFSSEHFKGIGQKT
                     AEKIIALYGNNPIDEILKNPSRLNEISSLSKANREAFVAKLKANYGTEQVIAALADLG
                     LANRFAFQLFDKYKEEAVHIVKDNPYQLIEDIQGFGFKLADSLAEQLGIESASPKRFR
                     AALLHCLLEQSIKRGDTYIQARELLALTISLLEDTRPVECDPAIVANQLTQLIDEGKV
                     MTIGTRVFDSSLYYAEDGIQKHLTRLLQQPLTKEPSQDTIDQEIQAIQEELAITYDKI
                     QKQAISQALTSKVFILTGGPGTGKTTVIRGILQAYASLYQIDLKQKDIPIILAAPTGR
                     AARRMNELTGLASATIHRHLGLNGDNDYQAMEDYLDCDLLIVDEFSMVDTWLANQLLT
                     AINSNTQLIIVGDSDQLPSVGPGQVLADLLKVDRIPHITLDKIFRQSEESTIVDLANH
                     IRQGILAPDFCQKKADRSYFEAQAPFIPGMMTKIVQAALKSGIPAEEIQILAPMYKGL
                     AGINSLNQLMQNLLNPLANQTEFLFNETAFRKGDKVLHLVNDAQLNVFNGDIGYITDL
                     IPAKYTESKQDEIIMDFDGTEIVYPRNEWLKITLAYAMSIHKSQGSEFQVVILPVTRQ
                     SGRLLQRNLIYTAITRSKSKLIMLGEIAAFEEAIKKEGDKRHTYLVQRLQVAEADDHT
                     AAASVKESNQSSLSVMPATSPQKEQEQPPYLLTPHNFLAIDPMIGLTEDDMLTFFKKK
                     S"
     gene            10212..10697
                     /locus_tag="TV191_000441"
     CDS             10212..10697
                     /locus_tag="TV191_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1506987.1"
                     /translation="MISYEQVRQALRTSTITIIIINAISMVITLFGLAGIFFLKSQLD
                     KPEFRAQFSAEQLRLFEVGISPFTIFMSVISLGLVVLTTVLCGFNLSKIKQGSTVSYV
                     PYIIGIVLYLISIVSQLFSQIEPVSMIIVLAELALYGFAFYKAKTLNEKDKDNPQSIE
                     E"
     gene            complement(10840..11943)
                     /gene="dinB"
                     /locus_tag="TV191_000442"
     CDS             complement(10840..11943)
                     /gene="dinB"
                     /locus_tag="TV191_000442"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEL1506988.1"
                     /translation="MLIFPLINDTSRKIIHIDMDAFFAAVEERDNPELKGKPVVIGKN
                     PRESGGRGVVSTCNYEARRFGIHSAMSSKEAYERCPQAIFISGDHAKYRRIGYDIREI
                     FKRYTDQVEPVSIDEAYLDVTTNKLGIKSALKIARLIQHDIWNSLQLTCSAGVSYNKF
                     LAKLASDFEKPHGLTLVLPDDALPFLEKLPIEKFHGVGKRTVERLHEMGIYTGQDLLR
                     VPEMTLIDQFGRFGYELYRKARGISHSPVKPNRMRKSISSERTYAKLLYQEADIKAEL
                     SKHARRVADLLEANKKLGRIIVLKVRYADFTTLTKRVSLPELTRDARIIDQVARELFD
                     SLEEHQAGIRLLGVTMTGLKDKVTDILLDLSFN"
     gene            12152..14476
                     /gene="pflB"
                     /locus_tag="TV191_000443"
     CDS             12152..14476
                     /gene="pflB"
                     /locus_tag="TV191_000443"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEL1506989.1"
                     /translation="MATVKTNADVFEKAWEGFKGTDWKEKASISRFVQANYTPYDGDE
                     SFLAGVTERSLHIKKVIEETKAHYEATRFPYDTRPTSIADIPAGFIDKDKELIFGIQN
                     DELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKHVTTVNDGIFRAYTSNIRRA
                     RHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAITEIDEESIRLREEI
                     NLQYQALGEVVKLGDLYGVDVRRPAENVKEAIQWVNIAFMAVCRVINGAATSLGRVPI
                     VLDIFAERDLARGTFTESEIQEFVDDFVLKLRTVKFARTKAYDALYSGDPTFITTSMA
                     GMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYAFRRYCMHMSHKHSSI
                     QYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNGGY
                     DDVHKDYKVFDIDPVTDDVLDFDTVKANFEKSLDWLTDTYVDALNIIHYMTDKYNYEA
                     VQMAFLPSHQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYPRW
                     GEDDPRSNELAEWLIEAYTTRLRSHKLYKNAEATVSLLTITSNVAYSKQTGNSPVHRG
                     VYLNEDGTTNLSQLEFFSPGANPSNKAKGGWLQNLNSLASLDFSYAADGISLTTQVSP
                     RALGKTHDEQVENLVTILDGYFENGGQHVNLNVMDLNDVYDKIMAGEDVIVRISGYCV
                     NTKYLTPEQKTELTQRVFHEVLSMDDAAEAISGK"
     gene            14785..15063
                     /locus_tag="TV191_000444"
     CDS             14785..15063
                     /locus_tag="TV191_000444"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1506990.1"
                     /translation="MKRLKTLCLLATAITLTLAPISTSQTTTQTVYASETHQNLCTNT
                     GNGWFKCPDGHGGWTWHFDENHKSNQQSFLGGLLGFALSLWGAIIRLF"
     gene            complement(15227..16168)
                     /locus_tag="TV191_000445"
     CDS             complement(15227..16168)
                     /locus_tag="TV191_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEL1506991.1"
                     /translation="MTLEVIEKVSQQIQEGLYHGASLALFRCGGWQEHYIGTLDGQRP
                     VTKGLVYDLASVSKVVGVATVCIAMINSGALALDTPLRHYYPDAQKLEVTLRQLLTHT
                     SGLDPYIPNRDQLNAQQLRAAMHQLQVKDDKTFHYTDVNFLLLGFMLEHLHGKSLDEL
                     FQEMVFTPFGMTETSFGPRPEAVPTVKGVLDGEVHDPKAKVLGNHAGSAGLFSTIRDL
                     ERFIEHYLKESFSDRLFQSYSRQEKPRSLGWSLEGDWISHTGYTGPFIMLNKKEQQAA
                     IFLTNRTYDKDDRALWIKERRQLRDAIHRTFDRNSPR"
     gene            complement(16165..16920)
                     /locus_tag="TV191_000446"
     CDS             complement(16165..16920)
                     /locus_tag="TV191_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEL1506992.1"
                     /translation="MTLFDNIVFKTPVLRVNNRDLNIAFYQKNLGLRLVSEENAISIF
                     SSWGQGQERFVIEESPAARTRVVDGPKKVNTIVIKTTAPKDIEQLLAHGVDYDLIFKG
                     KKGYAFEVTSPEGDRFLLHAEDDIKELDIVDDVPAIDKEADFRGLSQFSFDLIVLNVL
                     DDEQSRAFYQSIFGDCLPVTLEFNREAGQDLTIVPHVTWDLEILEFQVSDSYDLLALK
                     TYLEDKGCQVYLDKKARVLVLSDPSQIEIWFVK"
     gene            complement(17413..18261)
                     /locus_tag="TV191_000447"
     CDS             complement(17413..18261)
                     /locus_tag="TV191_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEL1506993.1"
                     /translation="MEITWTVKYITEFIATAFLIILGNGAVANVDLKGTKGNRSGWLV
                     IAFGYGLGVMMPALMFGNVSGNHINPAFTFGLAVSGLFPWAHVLQYVLAQLLGAMFGQ
                     LVVVAVYKPYFVQTDNPNNILGSFSTISAVDDGDKGSRKAAYINGFLNEFVGSFVLFF
                     GAMALTKNYFGVELVGKLVEAGYDQTTAATQISPYVTGSLAVAHLGIGFLVMTLVTSL
                     GGPTGPALNPARDLGPRLVHHFLPKSVLGQAKGDSKWWYSWVPVAAPVLAAVAAVAAF
                     KFLYIK"
     gene            complement(18363..18815)
                     /locus_tag="TV191_000448"
     CDS             complement(18363..18815)
                     /locus_tag="TV191_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEL1506994.1"
                     /translation="MISKYKRILAAVDGSYESELAVEKAINVALRNDAVLLLAHVIDV
                     KAYQGDAMVSDYVFDTQEEHAKEVLRYYEKMARGRGVSSIKKIIERGNPKKLLASDIP
                     EKEQADLIMVGATGLNTFERLLIGSTSEYILRHAKKDLLVVRNCEKTL"
     gene            complement(18835..20034)
                     /locus_tag="TV191_000449"
     CDS             complement(18835..20034)
                     /locus_tag="TV191_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1506995.1"
                     /translation="MEDKLFNKHFIGITVLNFIVYMVYYLFTVIIAFVATKELGAKTS
                     EAGLATGIYILGTLLARLIFGKQLEVFGRRLVLRGGAIFYLLTTLAYFFMPTIGMMYF
                     VRLFNGFGYGVVSTATNTIVTAYIPASKRGEGINFYGLSTSLAAAIGPFVGTFMLDNL
                     HIDFRMIIILCSVLIAVVVLGAFAFPVTDIALNSEQLAKTKSWTVDSFIERKALFITL
                     IAFLMGIAYASVLGFQKLYTTDIHLTTVGAYFFVVYALIITITRPAMGRLMDVKGEQW
                     VLYPSYLFLALGLFLLGSVTSSLPYLLSGALIGFGYGTFMSCGQAASIKGVEEHRFNT
                     AMSTYMIGLDLGLGAGPYLLGLIKDMLLGSGVQSFHQLFWLAGLIPAACAVMYFLKTQ
                     AKAIDKG"
     gene            20203..20862
                     /locus_tag="TV191_000450"
     CDS             20203..20862
                     /locus_tag="TV191_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEL1506996.1"
                     /translation="MNHQILQRYIDSHNFPIIEKGYHKYLTFESLEEDFTYILKEGIV
                     KQSVLSKYGMEFNLRYVTGLEITSVLNTGYSKDMREPYNVRIESETASFYKVRHSTFL
                     RDISEDIELQGYVKDFYHYRLQKSMKKMQCMLTNGRIGAISTQIYDLMTLFGRPLANG
                     HILIDFIITNEELGKFCGISTASSVSRLLKQLKKEGIIQINDQHIIITNLEKLKDNIV
                     F"
     gene            20883..23168
                     /locus_tag="TV191_000451"
     CDS             20883..23168
                     /locus_tag="TV191_000451"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEL1506997.1"
                     /translation="MRYNQLSYIPTSLETAVAELQALGFAVQQEQAPKENFAIFLRKL
                     FFHFQDTDYPLSHMIASKDLDLLTFLTSDATLTKEVFDLVALQVLGFIPAVDFTDAQD
                     FIQKIGFPIVFDSQQLLLNLHQLLATRQKSGVTLIDSLVSQGLLPMDNCYHYFNGKAL
                     ATFDTTSLIREVVYVEAPLDTDQDGQLDLIKVNIIRPKASTAIPSMMTASPYHQGINE
                     TANDKKLHRMEGELSPKAPRRITVEPTDFQPLATKPSRLPVNECQETFSHISSYTLND
                     YFLARGFANLYVSGVGTAGSTGFMTSGDYAQIESFKAVIDWLNGRATAYTSHKRDYQI
                     KADWSNGLVATTGKSYLGTMSTGLATTGVDGLAVIIAEAAISSWYDYYRENGLVCSPG
                     GYPGEDLDVLTELTYSRNLLPGDYLRHNDHYQQLLSQQSQALERQSGNYNQFWHDRNY
                     LPQADRIKCEVVYTHGLQDWNVKPRQVYNIFNALPDSLGKHLFLHHGEHVYMHNWQSI
                     DFREAMNALLCQKMLGQNNGFTLPTIIWQDNQKEQTWKELTAFGGHSKRQIALGDDHV
                     LIDNHYGEEDFKRYSKDFRAFKAELFEGKANQAVIDILLEEDLPINGQACLKLKLKSS
                     ENKGILAAQLLDYGKKKRFADIPAILELDSIDNGQQFAREALKELPFKDSPYRVVTKG
                     VLNLQHRSDLLTIEDIPNDQWMTITFHLQPTIYHMAKGDTLRVVLYTTDFEHTIRDNS
                     NYALTLDLEQSYLLIPTDEEE"
     gene            complement(23274..23666)
                     /locus_tag="TV191_000452"
     CDS             complement(23274..23666)
                     /locus_tag="TV191_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HEL1506998.1"
                     /translation="MLTEEMKEMIAEQLAMVVTVDNEGNPNIGPKRSMRLLDDETLVY
                     NENTGGQTCSNIQANGKIEVAYVNREQLRGYRFVGRAEIITEGPVFEAAKEWAEGKMG
                     APKAAGLIHIESVYSLHSGAEAGKKVSK"
     gene            complement(23820..24077)
                     /locus_tag="TV191_000453"
     CDS             complement(23820..24077)
                     /locus_tag="TV191_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1506999.1"
                     /translation="MSKATLKELRIAQKKTQKELSALTGISVRTLARYEKDVQKLRRA
                     KYEKLRGIAEALTISVDDIFFGRRFGFYEIKSACLLIAFLL"
     gene            24256..24630
                     /locus_tag="TV191_000454"
                     /pseudo
     CDS             24256..24630
                     /locus_tag="TV191_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678526.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(24888..25670)
                     /locus_tag="TV191_000455"
                     /pseudo
     CDS             complement(24888..25670)
                     /locus_tag="TV191_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514970.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
     gene            complement(26187..27695)
                     /locus_tag="TV191_000456"
     CDS             complement(26187..27695)
                     /locus_tag="TV191_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1507000.1"
                     /translation="MLEEYLEPVINHQALLLTILLGKKRISFHAIQQKTGFSLANIKR
                     YIHQLEELFQGDIAFEWDSTIVRCTVLKRGKPFLKTIYRQSVRLHILKFLLIKAPCYK
                     VKSVSGFAREHFISTPSAYRLIQHMKPFVEECGLALEDNSVVGEEWRIRYLIALLHDK
                     YGIVIYELTDHDLDIVHDFIFSIKKQQTPHPLLDKKFRFFDVLLSLSWKRGEFDVAIP
                     QEGIFKRLKSLALYGYLEDFFKREGKLLLDMDFPSSEIDYIFLVYLTVNNSFSITQWS
                     EEDSSALLTIIQEDPAYQELLGELRQLFGHYIAFDKACIQTLIPYFRKTLFDLSLFIP
                     QKYYYAEEYQGSKLLANRIELMINSWAERVSGVGRLTGSNLHLLCTRLEQLVREGLPP
                     LAIAVIEINKKNIDILYSLVMQQVSPCVAKVYRFNILSEAELPWRTDFDLIVTTAEMT
                     AFIEERLSLNENTKILDFNFDFVMYQAEYLSQVIRELRDKQYQEALDTILNG"
     gene            27946..28842
                     /locus_tag="TV191_000457"
     CDS             27946..28842
                     /locus_tag="TV191_000457"
                     /inference="COORDINATES: protein motif:HMM:NF012162.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1507001.1"
                     /translation="MKTKSFRKVLTTSATCIVLATSFAGGTLRVWAEQLYYGWNDGTR
                     QSSPYFLYVSPKNAPKRELKDEYVVYCFNKKLYWPDQWESIYSNFNDIRSPYNDLPVY
                     EKKLGYDGIFKQYAPDYKKDISDIASALVAVLSNGYPTNKSQLSTSYHLNNDSSRKVT
                     QLAIWYFSDSLTKEYLKDTGGYNLNDMEKKALDFLISKGEDSKLKSEQSNYSLDIYVY
                     QSGGHDHMKDYQNLLGSTLIPKEPLKPQLGGFSGHNGNGLSGLEGGSSGSQETNEDGK
                     KGLIGFHGGLSGSEGKRDPFQD"
     gene            28890..29102
                     /locus_tag="TV191_000458"
     CDS             28890..29102
                     /locus_tag="TV191_000458"
                     /inference="COORDINATES: protein motif:HMM:NF014980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein"
                     /protein_id="HEL1507002.1"
                     /translation="MQSLEGGNSPIVEQNYGSTEGYHGQSGILEETEDTNPPGIILGG
                     SGNVETRSSSDGAWRWSSWRIRRNDT"
     gene            29029..29835
                     /locus_tag="TV191_000459"
     CDS             29029..29835
                     /locus_tag="TV191_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEL1507003.1"
                     /translation="MSKRDPHLMGLGGGLAGESGETTPKPGQTGGHGPIIETTEDTQK
                     GMSGQSGGTIESENTKKPEVMIGGQGQTIETTEDTQKGMSGQSGGTIESEDTKKPEVM
                     IGGQGQTIETTEDTQKGMSGQSGGTIESEDTKKPEVMIGGQGQIIDFSENTQSGMSGQ
                     SGDTTVIEDTKKSEIIIGGQGQIIDFSEDTQPGMSGQSGGTTIVEDTKKPTPKPKPAP
                     APIVNDEKPNKGTQLPQTNDMKQLTLSIIGAMSMLLVLCLSLFKRPSKKD"
     gene            complement(30207..31253)
                     /locus_tag="TV191_000460"
     CDS             complement(30207..31253)
                     /locus_tag="TV191_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEL1507004.1"
                     /translation="MRLRTYIVIGYLMSMLITIAGLIVGLNQMLITIEDISYILVIAL
                     IASVAGGIVNMILLSNVFSSLKRLKKKIQAISERNFDSGQLIKCPLEFKDLEEAFNQM
                     SSELKVSFESLSESEHEKSMMIAQLSHDIKTPLTSIQATVEGILDGVIPREEERHYLN
                     TISRQTNRLNQLVEELHMVSLNDQKQDDKQQLQIIYLEKLLIDMLSEFQLTLEQEKRS
                     VHIEVAKEVVKISSRYDALSRIMLNLVSNALKYSKANTALTIHAYQQEQSIRIDVIDQ
                     GQGIKKEDLPLIFKRLYRVEASRNMKTGGHGLGLSIARQLARQLGGDIAVESQLGKGS
                     CFSLLLPASPPLGD"
     gene            complement(31255..>31395)
                     /locus_tag="TV191_000461"
     CDS             complement(31255..>31395)
                     /locus_tag="TV191_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HEL1507005.1"
                     /translation="WEEEYLDDTNTLNVHIHSLRNDLAKYSTEQTPTIKTVWGLGYKL
                     EG"
BASE COUNT         9386 a         7384 c         6253 g         8372 t
ORIGIN      
        1 gaagctaaga agcctgaaca acctaaacca atgactaaac caggagctaa gaagcctgag
       61 caatcacttc catcaactgg tgacatcaga aatccattct tcacgcctgc agctattgct
      121 attatgatcg cagcaggtac cattgccatt ccaaaacgca aggaagaaga ttaaacaaat
      181 taacaatccc catatttcaa caatgataca caagccccta cttgtgtcca cctcaaaagc
      241 agtagccagt cgcgcggcta ctgcttttac tatgcttttt ttacaccagc tctgatagca
      301 gctaataaca aaaaagattg aagacacagc ttattgggtc cccgatcttt ttttggtcat
      361 acaaccaaca gcagctcttg aggcttgctg tccttctaag aggctgttgg cttgttgctt
      421 tagcttaatt ctgctacgat agccttgatt tgatccttgg tatggacgcc tgctacttgc
      481 ttgacaacct taccgtcctt tttgaacagc agggttggga tagacataat gccaaattgt
      541 tgagcagtat tgggattgtc atcaacatct agcttgacaa tcttaagctc agcttcgtca
      601 atttctgctg ctaattgatc aaggattggc gcttgcatta agcaagggcc gcaccaggtt
      661 gcccaaaagt ccacaaggac taggccttca ttagtttctg cttcaaatgt tgcatctgtt
      721 acgatatgtg ccattgtaat ctccgttctt atagtttata agcctatttt aggggaaaac
      781 gactgataat gcaagaatct gatacgaaga cctcggtctt atgatttaag aaaaatctgg
      841 cgtagccatt ttaagacaaa tacgctggcc tttgctacaa tgaccttatc ttaacaacta
      901 aaaggaggct actatggaag catacgagct tattgtgatt ggatttggta aggccggaaa
      961 aactttggct gccaaaatgg cgcagctagg aaaaagagtt gcccttattg agcagagccc
     1021 cactatgtat ggcgggactt gtatcaatat cggctgtatt ccaacaaagg ccttaatcac
     1081 tgctgctgag cataatgcta gctttgcaga cgctatggcg cacaaagata ctgttgttca
     1141 tcgtcttcgc caaaaaaatg agcagctgct agctcagtct ggtgtgacac tttacaacgg
     1201 taaggcaagc tttgtctcta ataagacgat tcaagtagaa gcagggcagg agcggatcct
     1261 cttagagggc aagcatatcg tgatcaatac cggagctgtt tcaaatcgct ttccgatacc
     1321 tggtctagca gatagtcagc atgtggttga tagtacaggg attctagctc tcactgagca
     1381 gcctcagcgc ttggctatta tcggtgcggg gaatatcggg ctagaggttg ccagccttta
     1441 tgccagctta ggcagcgagg ttactatgta tgaggctgca cctgctattt tagggcgcta
     1501 tgagccggtt gtcgctgagc tggcacagga ttacctggaa aaagctgggg ttacctttaa
     1561 gctctctgcg actgttgagc tgattgctaa tgatgaagca ggtagagttc tagtgactgc
     1621 taatggcaag acagaagcct ttgattgtct cctctatgct atgggacgta agcctgccac
     1681 tcaaggcctt ggcttggaaa acactgacat taagcttgat gatcgctatg ctgtcgtggt
     1741 agatgattat tgtcaaacca ctgtcgaggg gctatatgcg gttggtgatg ttaatggcgg
     1801 gcctcaattt acctatacgt ccttagatga tttcaggatt gtgtttgggc agctaacagg
     1861 cacaagccag tacaaccaca aagatcgggg ctatctgcca acaacagtct ttatcgagcc
     1921 gccactttca caaattggtc taacagaaaa agaagcaaaa gagcagggac tgccctacaa
     1981 ggctaatgag ctcttggttg ccaatatgcc acgcgcccat gtcaataacg acctcagggg
     2041 gatttttaag gtcattgtca atacagagac taatgaaatt ctaggggcaa ccttatttgc
     2101 taacaattct cacgaataca ttaacctgat taagatggct atggataacc agattccata
     2161 tacctatctc aaaaaccagc tctttaccca cccgtcaatg gctgaaaatc ttaatgatgt
     2221 ctttaacctt taaaagaacc tcaacctcac ctgcatagca ggtacaacag ccaaactatt
     2281 aaaaaaacaa actccttttt ggctgcttat cacatggata ggcggctagc aaaaggagct
     2341 tgttttttct tgtatccaat cagcaggcta gcagctgctc atggtctaaa ggaactagct
     2401 aggctgggac acgttggtag caaaagtcca gcaagactca ctagctgctg tcatgagctt
     2461 tgaagagcag cacttaggga acacgcccag tagctttctt tgggacgctt ggctcaccta
     2521 gggctcaatc agcttgagta aaaaggggct ttatttgaat caagaggatc aattagccta
     2581 gattagctat ggtacagcct gagccgccag cattttgcgg ggcatagcca aagcttttga
     2641 catgcttgtt gcgtcgcaag tacttgccga ccgcttcacg tataacacct gtaccaatac
     2701 catgtatgat gtcaacctga ctcatgttgt taagcaaggc ttggtcgata aaggcatcta
     2761 gctcctgcat ggcctcctca tagcgcttgc ctcgaaggtc taagcgagcg cgcggccctt
     2821 ttcctgtagc tgcttttttg acgaccttga cagctctctt cttaggctgc tgcgcttctt
     2881 cttttagctt aaccaagctg aattcgtctt ccttgagggt caacttgatc aggccaacct
     2941 gagcctccca cctcttgtcc ttaagctggg caagcaaggt tcctctttgc ccataggcgg
     3001 taacaatgat gtcatcaccc acacgaggag cccgccattt tttcgctttt ttcagcacct
     3061 tattttgcga caggctttgc tctggcgcaa gctgctttag gcgatgcttg gcttcgataa
     3121 tttcgtgcgg ctttagctct gccttttcat gcagctgact taaaatgcta tcactttctg
     3181 ccaaggctat atccacaatc tcacgcgctt caagggctgc cttttccaat tccttgtcct
     3241 tagcgtggga gaactcgtta tagagctttt taacagcacg attgaatttg aggttatcct
     3301 gctcgacctc cttgatatgc tcaaggcgct tgcggctttc taacgtttgc tgctctagtt
     3361 gctcaatgat acgattgaca tcatgatcag ttgcggtcat cgcctgagct tccttgacga
     3421 tgtgctctgc taagcccaat cgtctcgcaa tgtcaaaagc atttgagcga ccaggcactc
     3481 cttgcatgaa gcggtaagta ggctttaggc tgacattgtc aaaggccatg ctggcatttt
     3541 caacataggc tatctcaatc ccataggcct ttagctctgg gtaatgggta gtggccatcg
     3601 tcttaatatt ggtcagacgc agctgctcca aaatagccat agcaaggctg gctccttcct
     3661 gtggatcagt ccctgctcct agctcgtcaa agaggatcaa gctgtcactg tctgcctgat
     3721 tgagaatctc aacaatgtga gtcatatgac tggaaaaggt agacaggctt tgctcaatgg
     3781 attgctcatc tccaatatca gcataaatac cattaaaaac tgccaccctg gagcccttgt
     3841 cagccaaaat aggcagccct gactgggcca tcacctgagc aagccccaag gttttgagca
     3901 tgatggtctt accacctgta ttaggaccgg tgatcacaat tactgctaag tcatttgcaa
     3961 aatgcagatc atttgccaca gggttttgaa tcaaggggtg gcgcgcattg agcagctgta
     4021 agcttttatc gtcagaaatc actggcacag ttgcctgttt ggcttgcata taaaggtatt
     4081 ttgctctcac aagatctaaa tgtcctagta gccaagcgtt attcctaaga gatcgactat
     4141 gcggacgcag ctgctctgac agctcatgca agattcgtcc aatctcatgg cgttcatctg
     4201 tctgtagctg agtcagctcc tcattgagac ttacaagcgc tctaggctca atgtagaccg
     4261 tactgccaga agctgacatg tcatgcacaa cgcctgccac cttatgacga taggtgtttt
     4321 tgacaggcag gacacttcgg ccattacgac tagcaatcag gctctctgac aaataagctg
     4381 cctgtttttt taggatatcc tgcaggagct gacgactggc atgctccttg tttgatatct
     4441 gacgacgaat gctctccaat tcaggactag caaagccttc aacaaagcct gcgtcattaa
     4501 tggcttggag actcccctgt aagctaggaa agctctctat tttttcaaag agtgctttta
     4561 gagcgactaa atcaacattt tccaaatcag cgtaaaaacg acagacctct gccgacacct
     4621 gcaggagctt tttaactgct aaaagctctt gaatgctcag atctgcctct aaatccaaac
     4681 gctgcatgct ttctgagaca tctgatagcc ctcccaaggc aaaatggtgg tgctctacaa
     4741 aaatagccgc catttcctca agctctgtaa agtaagcctg tattttgtct ttattcgcaa
     4801 taggctccaa caagtcaagc tctagctgcc cctgctctgt ctgtaaataa ggccaaaatt
     4861 gctctttaac cttttcaaat tctaactgtt ctaaaatctt tttttccata gttcttatta
     4921 tacctaaaaa tcacttaaaa tgtgggacac taaacaaaaa gagaccagag agactctgac
     4981 ctcaaagaat agctgttacc cataattgcc tgagaatgct tgagataaag ggacaatgct
     5041 caaccaagag gcgagacaaa agactgccat gtaggcgccc ttgaataaag ggcatgggaa
     5101 tggtagcaag aacggtcaat gccatgctta aaaacaaaac cgaaaccatc accgccagca
     5161 agccactggc tagcttagcc tcaaagccat caaaataatc caccggcgca aggtgcacca
     5221 agacacccgc caatcgaacc acagcatagc ctactgtaga cagtataaaa aatgctatcc
     5281 ctgcataata aaccttatcc aattcaaaaa tattaatatc cttaaaaaat aaggtagctg
     5341 ctccctcagc aggattagaa taaggcaccc atagagccag cttgcctgcc agagccttat
     5401 agccatgatg ggcaaacaag agcgacacca aggccccaaa acaataaaag gtctgaagga
     5461 taagccctct attgtagcca atgtaaaagc tccaagaaag cagtaacaat ataagcactg
     5521 agagcatcat gacacctcat ctgtatctgc ttgactagcc ttttcctgaa tacctgccag
     5581 tgccttctca cgcagctcga caatctcagc ttcgattttt tcaatctcaa tctctctact
     5641 cagttgggct gacagggtat tgatggtcat caaaatagca acggtttcgt cgtctgcttc
     5701 tggcagacgc tccttgatgg cctgatattt ttcctttgcc acacgatcaa cctcttccat
     5761 aaagaggttg tctttgtccg ttgtcaatgt taatgtcttc tcaccaaatg ttaatttgta
     5821 acgattaata ttcttcatag gctcacccct ttagcattat accctaaaaa tgacttttcg
     5881 taaaattgtg aaattaatct gagattgcat ggaatgattt cccataacag gacattttat
     5941 gttaaaataa tgttcatgga caccttagtt ttcaaaatca attcccaagt cagcagcagc
     6001 ctgatcaagc agctagcacc ataccgcata agcaatgcca atccttacgt tagactggct
     6061 gccaaaaaag atggtgtcac actgatgctg tatacctcag gcaagctggt gctgcaaggc
     6121 agacaggctg caaagctggc tcaagagctt gatctgcaag aaacgcctgc tgatcagaga
     6181 cccgcaccct ccagcgcaca ggatatcccc ttaattggta gtgatgaggt gggaaatggc
     6241 tcttactttg gaggcattgc tgttgttgct agctttgtgc agccagagga gcacgccttg
     6301 ctcagacagc tcggtgtcga tgattctaaa aacctcaatg ataagagtat cgcccagatc
     6361 gctcctgtcc taaaaaagca tattcaacac agggcgcttt tgctatcgcc taaaaaatac
     6421 aatgaaatgg taggtaaggg gaagccctac aacgctgttt ctgtcaaggt tgctcttcat
     6481 aatcaagcga tttttctgct cttaaacgac ggagcaagac cagaaaaaat tgtcattgat
     6541 gccttcacaa gtcaggccaa ttatgacaaa tacctacagc aagaaaaaaa tcactttcgt
     6601 aatcccttga cctttgagga gaaggccgaa ggcaaatatc tggcagttgc tgtcagctct
     6661 atcattgcta gacagctatt tttagacaat cttgacaagc tcagtcaaga tctgggctac
     6721 cggttgccta gtggtgctgg gcgtccatct gatcagattg ccagtcaaat cttagccgcc
     6781 tatggtatgg caggcttaga gcattgcgct aagctgcact ttgcaaacac caaaaaagcc
     6841 caagcgctac taaaaaaaca ataatcttag aaaaataaag gaaaagtcat gaaacaattt
     6901 attaaagaat ggggagcttt tacccttttt atcctacttt ttggactctc acgtttgttc
     6961 ctatggcagc ctgtcaaggt tgatggccac tcaatggacc caaccctagc acatggcgag
     7021 aggctcatta tcttcaacaa ggctaagatt gatcgctttg atattgttgt tgccagtgag
     7081 gaggacgaga acggacagag aaaagagatt gttaagcgtg ttgttggcat gccaggtgat
     7141 aagctgtctt atagaaatga cactctttat atcaacaaca agaaaacaaa agagccttat
     7201 cttgatacct acctgacgag ttttaaaaag gacaaattac aatcaaccta tgcttacagt
     7261 gatctcttcc aagagctggc tgaaaatgct gctgccttta ccgtcaactc cgaaggaaaa
     7321 acagaatttg acatcactgt tccaaagggc gaatatttcc tactgggtga tgaccgcatt
     7381 gtatctcgtg acagccgcga ggtcggctcc tttaaaaagc aggacatcgt tggtgaggtt
     7441 aagttccgct tttggccact caataaaatc aatctcttcc ctagatagca ggcaagctaa
     7501 agctattttc tagcagggct gatataggct ctatgcccac agcagtaaag actcagggca
     7561 gcaatagcct ctatctatat ctgcttatct atccatacca agaggcttga tgtgctatcc
     7621 aagcactcag ctagctttag agaagcagct attgttgacg ttctaaaacc tgccgttgtg
     7681 caggttttcg actatcttgc acagaaaggt accgtcatgg aacacttttt tacaggcact
     7741 gttgaccgaa ttatctttga caatgcgtca aattttttca aaattctatt actggctata
     7801 gaggatactg atagtgattt tgatgaagct gacattgtca ttacaggcac tatggctgag
     7861 atcatagagg gcgaagccta taccttttgg ggtgagctga cccagcaccc aaggtatggt
     7921 cagcagctgc gcctgagccg ctatcaaaag gctaagccca cctcagcagg tctcgttagc
     7981 tatttttcca gtgagcattt caagggcatt gggcaaaaaa cagctgagaa aatcattgcc
     8041 ctttacggta ataatcctat tgatgagatt ttaaaaaatc ccagtcggct taatgagatc
     8101 tctagccttt ctaaggctaa tcgtgaagcc tttgtggcaa agcttaaagc caattatggc
     8161 actgagcagg tgattgctgc cttggctgat ctaggactgg ccaatcgctt tgcctttcag
     8221 ctatttgaca aatacaagga agaggctgtt catatcgtca aggacaatcc ttatcaactc
     8281 attgaggaca ttcaaggctt tggctttaag ctggctgata gcttagctga acagctagga
     8341 attgagagtg cctctcccaa gcgctttcgt gcggctctgc tgcattgcct gttggagcaa
     8401 tccatcaagc gaggcgacac ctatatccag gcacgtgagc ttttggcgct gaccattagc
     8461 ctattagagg acacaaggcc agtcgaatgc gacccagcta ttgtcgctaa tcagctaacc
     8521 cagctcatcg acgagggcaa ggttatgact attggcacgc gtgtttttga cagcagcctt
     8581 tattatgccg aagacggcat tcaaaagcat ctgacacgct tactacagca gcctctgact
     8641 aaggagccta gtcaagatac cattgaccaa gaaatccaag ccatacaaga ggagcttgct
     8701 ataacctatg acaagatcca aaagcaggcc atcagccagg cactgaccag caaggttttc
     8761 attctaacag gaggcccagg cacaggaaag acaaccgtta tcaggggcat tttacaggcc
     8821 tatgccagcc tgtaccagat tgacctgaaa caaaaggata ttcccattat cctagcagct
     8881 ccaactggtc gagccgctcg tcgtatgaac gaattaaccg gtctagcaag cgcaactatt
     8941 caccgccatc ttgggttaaa cggagacaat gattaccaag caatggagga ttatttagac
     9001 tgtgatttgc tgattgttga tgaattttcc atggttgata cctggctggc caatcagcta
     9061 ttaacagcca tcaattctaa tacccagctg atcatcgtag gagatagcga ccagctgcct
     9121 tctgtcggtc ctggacaggt actagctgac ttgctaaagg ttgatcggat ccctcacatt
     9181 acccttgaca agatttttcg ccaatcagag gagtcaacca ttgttgattt agccaaccac
     9241 atacgccaag gcattcttgc tcctgatttt tgtcagaaaa aggctgatcg ctcctacttt
     9301 gaagcgcaag cgccattcat tcccggcatg atgacaaaga tcgtacaggc tgccctaaaa
     9361 agtggcatcc cagctgagga aattcaaatc ctagccccta tgtacaaagg actagcaggc
     9421 atcaacagcc tcaaccagct catgcaaaac ctcctgaatc ctctagctaa tcagacagaa
     9481 tttctcttta acgagacggc ctttcgtaag ggagacaagg tacttcacct tgtcaatgac
     9541 gctcagctta atgtcttcaa tggtgatatt ggctatatca cagacctcat tccagccaaa
     9601 tataccgaat ccaagcagga cgaaatcatc atggactttg atggcaccga gatcgtctac
     9661 ccaagaaatg aatggttaaa aatcaccctt gcctatgcca tgagcattca caaatctcaa
     9721 ggcagtgaat ttcaggtggt aatcctgcct gtcacccgtc agagtggtcg acttctgcaa
     9781 agaaacctca tctacactgc catcaccaga tcaaaaagca agctcatcat gctcggagaa
     9841 atagccgcct ttgaagaggc aatcaaaaaa gaaggtgaca agcgacacac ctatctcgta
     9901 caaaggcttc aagtggctga agctgatgac catacagcag ctgcttcagt aaaggaatca
     9961 aatcagtcta gcctatctgt aatgccagct accagcccac aaaaggaaca agagcagcct
    10021 ccttatctgc tcacccctca taatttccta gctatagacc ccatgattgg tctaaccgaa
    10081 gatgatatgt taaccttttt taagaaaaaa tcataatata ttaaaaaagt aaggcacaat
    10141 ccttattcct atgctataat atccatgtat catcttaaaa gtacaataac ataacattca
    10201 aggagactta tatgatttca tacgaacaag tacgacaagc actcagaaca tcaactatta
    10261 cgatcattat catcaatgct atcagcatgg ttatcacctt gtttggactt gctggcattt
    10321 tctttttgaa gtctcaattg gataaacctg aatttcgtgc acaattttca gctgagcagc
    10381 taaggctatt tgaggttggc atatcaccct ttactatttt tatgtcagtg attagccttg
    10441 gattggttgt tttgaccact gtgctttgtg gctttaacct ctcaaaaatc aaacaaggtt
    10501 ccactgtcag ctatgttcct tacattatag ggattgtgct ctatcttatt agtatcgtaa
    10561 gccaactatt tagccaaatt gagcctgtct caatgatcat tgtcctagct gagcttgcgc
    10621 tttacggctt tgccttttac aaggctaaaa cccttaatga aaaagacaag gacaatcccc
    10681 aaagcattga agaataagca ggccataaag gtatgataac aagacttcct gtctgccttc
    10741 aaatatggct ctttgtcagc ccactacggt tgacaaagag ccttttttaa ccactaaaaa
    10801 agcaagagga aaattgataa tgtcctcttg ctttttttgt tagttgaatg acaggtccaa
    10861 caaaatatct gtcactttat cctttagtcc ggtcattgtg actcccaata agcggattcc
    10921 tgcctgatgc tcctccaggc tatcaaaaag ctctctagcc acctgatcaa tgatcctagc
    10981 atctcttgtt aactcaggta ggctaacccg cttggtcaag gtcgtaaagt cagcataccg
    11041 aaccttcaaa acaatgatcc ttcctagttt tttattcgcc tcaagcaaat cagcgacccg
    11101 tcttgcatgt ttagaaagct ctgccttaat atcagcctcc tggtagagga gcttagcata
    11161 ggtacgctca ctgctgatgg atttgcgcat acgattaggc ttgactggag aatgactaat
    11221 gcctctggcc tttcgataaa gctcatagcc aaagcgtcca aactgatcaa tcagggtcat
    11281 ctcaggaaca cgcaaaagat cctgcccagt gtaaatcccc atctcatgca gcctttcaac
    11341 tgttcgctta ccaacgccat gaaacttttc aatcggaagc ttttctaaga atggcagagc
    11401 atcatcagga agtactaggg tcagaccatg tggcttttca aaatcactag ctagcttggc
    11461 taaaaatttg ttataagaaa caccagcaga gcaggtcaac tgcaggctat tccaaatatc
    11521 atgctgaatc agtcttgcaa tctttaaggc agacttgatg cccagcttat tggttgtcac
    11581 atctaaataa gcctcatcaa tagacacagg ctccacctga tccgtataac gcttgaaaat
    11641 ctctctgata tcatagccaa tcctacggta cttagcatga tctccagaga taaaaatagc
    11701 ctgaggacaa cgctcgtagg cctcctttga gctcattgca gagtgaatgc caaaccttct
    11761 tgcctcgtag ttacaggttg atacaacgcc ccgtccacca ctttctctag ggttcttgcc
    11821 gatcaccacc ggcttgccct ttaattcggg attatctctt tcttccaccg cagcaaaaaa
    11881 agcatccatg tcaatgtgta taatcttgcg tgaggtgtca ttaatcagcg gaaaaataag
    11941 cataggtccc tccctcctac attatactcc tttaggcttt taaagccaag gcagaggatt
    12001 gtatgacagt tttcaactgt ttcagcaaac tgtaatataa aagaatcttg tatttgtcaa
    12061 gatttttgct tgggaaatcg tttcccctat ggtaaactta gattgtaaat gtaacagatt
    12121 ggacttgtta ctagatttta aggagaaact tatggcaact gttaaaacta acgcagatgt
    12181 ttttgaaaaa gcttgggaag gctttaaggg aactgactgg aaggaaaaag cgagtatatc
    12241 tcgttttgta caggctaact atacacctta tgacggtgat gaatcattcc tagcaggtgt
    12301 tactgagcgt tcattgcaca tcaaaaaggt cattgaggag actaaagctc actacgaagc
    12361 aacacgcttc ccatacgata ctcgtccaac ctcaattgct gacattcctg ccggatttat
    12421 tgacaaggat aaggaattaa tctttggtat ccaaaacgat gagctattca aattgaactt
    12481 catgccaaag ggtggtatcc gtatggcgga aacaactctg aaggaaaacg gctatgagcc
    12541 agatcctgct gtacatgaga ttttcactaa gcatgtgaca acggttaatg acggtatttt
    12601 ccgcgcttac acgtcaaaca ttcgtcgtgc gcgccatgcc cacactgtaa ctggtctgcc
    12661 agatgcttac tcacgtggtc gtatcatcgg tgtttacgca cgtcttgccc tctacggagc
    12721 agattacttg atgcaagaaa aggtcaacga ctggaatgcc atcactgaga tcgacgaaga
    12781 atcaatccgt cttcgcgaag aaatcaacct gcaataccaa gcacttggcg aagtggttaa
    12841 gttaggtgat ctttacggtg ttgacgttcg tcgtcctgct gaaaacgtca aagaagctat
    12901 ccaatgggtt aacattgcct ttatggctgt ttgccgcgtg atcaatggtg ctgctacttc
    12961 tcttggacgt gtcccaatcg ttcttgacat ctttgctgag cgtgaccttg cacgtggaac
    13021 cttcaccgaa tcagaaattc aagaattcgt tgatgatttt gtcctcaagc ttcgtaccgt
    13081 taagtttgct cgtacaaagg cttatgacgc tctttattca ggtgacccaa ccttcatcac
    13141 aacctctatg gctggtatgg gtaatgacgg tcgtcaccgc gttacaaaga tggactaccg
    13201 cttcttaaac acacttgaca atattggtaa ctctccagag ccaaacctaa ccgttctttg
    13261 gactgataag ttaccatatg ctttccgtcg ctactgtatg cacatgagtc acaagcactc
    13321 ttcaatccaa tatgagggtg tgacaacaat ggctaaggac ggctacggtg aaatgtcatg
    13381 tatctcatgc tgtgtgtcac cacttgaccc agaaaatgaa gagcaacgtc ataacattca
    13441 gtacttcggt gctcgtgtga acgtgcttaa agcccttctt actggactta acggtggtta
    13501 cgatgatgtg cacaaggact acaaggtatt tgacatcgac cctgttactg atgatgtcct
    13561 tgactttgat actgttaagg ctaactttga aaaatcactt gattggttga ctgatactta
    13621 cgtagatgcg cttaatatca ttcactacat gactgacaag tacaactacg aagctgttca
    13681 aatggcattc ttaccatcac atcaacgtgc taacatggga tttggtatct gtggcttcgc
    13741 aaatactgtt gacaccctat cagctattaa atatgcgact gttaagccaa ttcgtgacga
    13801 agatggttac atctatgact acgaaacaat cggcgactac ccacgctggg gtgaggacga
    13861 tcctcgctca aacgaattag ctgagtggtt gattgaggct tacactacac gtctacgcag
    13921 ccacaagctt tataagaacg ctgaagcaac tgtgtcactg cttaccatca cttcaaacgt
    13981 tgcttactct aagcaaactg gtaactctcc ggttcaccgc ggtgtttacc tcaacgaaga
    14041 tggtacaact aacctatcac aacttgaatt cttctcacca ggtgctaacc catctaacaa
    14101 ggctaagggt ggctggctgc aaaacttgaa ctcacttgca agccttgact tctcatatgc
    14161 cgcagatggt atctcactaa caactcaagt atcacctcgc gcgcttggta agacacatga
    14221 cgaacaggtt gaaaaccttg ttactatcct tgatggttac tttgaaaatg gtggtcaaca
    14281 cgttaaccta aacgttatgg acttaaatga cgtttacgat aaaattatgg ctggtgaaga
    14341 cgttatcgtc cgtatctctg gatactgtgt caataccaaa taccttacac cagaacaaaa
    14401 aactgaatta actcaacgtg tcttccacga agtgctttca atggacgatg ccgctgaagc
    14461 tatttcagga aaataagcta atcttagcta gctaagagcc tgtctgttga caggttcttt
    14521 ttttatcaca catgcaatag gtacagctgt cctcagcagc tgaataacca gcagagctgg
    14581 ttgaaactac tagcaagcct atcattatca ttgtgaaaat cagacgatta accttttcat
    14641 taaaaaaaaa aaaaaaacga aactacggag aaaagctgat gaggagctct ttaaggctat
    14701 cagtcaacat gttaaactct tcttaggaag cgttaacaat aactaactgc taagctaagc
    14761 aattatctat taaggagaat aacaatgaaa cgactaaaaa cactatgctt gttagctact
    14821 gctataaccc taaccctagc tcctatcagc acaagccaga caacaacaca gaccgtatat
    14881 gctagtgaaa ctcatcaaaa tctttgtacg aacactggta acggatggtt taaatgtccc
    14941 gatggacatg gagggtggac ttggcatttt gacgaaaatc ataagtcaaa tcagcagtcc
    15001 tttttgggag gattgttggg ctttgctttg tctctatggg gagctattat tagactcttt
    15061 taagctctag cttaactaat cctcaaacaa caaaaataag ctcttagaga actaagctct
    15121 aagggctttt tgctgttctg ataagtaaaa accaagagac aaggacatca aaaacaagca
    15181 ggcctatcag atataccacc tgataggccc acttgtgctc tcattcttat ctaggactat
    15241 ttctgtcaaa ggtcctatga atagcatccc gaagctgtcg tctctctttg atccacaagg
    15301 ccctatcatc cttgtcatag gttctattgg tgagaaaaat cgctgcctgc tgctcctttt
    15361 tattgagcat gataaaaggc cctgtatagc ctgtatgact aatccaatca ccctctaggc
    15421 tccaacccaa agacctgggc ttttcctgtc tgctatagct ttgaaaaagt ctatccgaaa
    15481 agctttcctt caggtaatgc tcaataaacc gctctaaatc cctgatggtt gaaaaaagcc
    15541 ctgctgagcc tgcatggttt cccaagacct tagccttggg atcatgtacc tctccatcaa
    15601 gcaccccttt gaccgttgga actgcttctg gccttgggcc aaaggaggtc tcagtcattc
    15661 caaagggagt aaaaaccatc tcctgaaaaa gctcatcaag agactttcca tgaaggtgct
    15721 ctagcatgaa gccaagcaat aaaaaattca catctgtgta atgaaaggtc ttatcgtcct
    15781 tgacctgaag ctggtgcatc gctgctctta attgctgggc attgagctga tctcgattgg
    15841 gaatataagg gtcaagtcca ctagtatggg tgagtagctg tcgcagtgta acctccagct
    15901 tttgagcgtc aggataataa tgccttaaag gagtatcaag agccaaggca ccactattga
    15961 tcatggctat acagacagtc gctactccga caaccttaga gacactggct aaatcataaa
    16021 ccaagccttt ggtaacaggt ctttgaccat caagggtacc gatataatgc tcctgccaac
    16081 cgccacagcg aaaaagggct aagctagccc catgatataa gccttcctga atctgctggc
    16141 ttaccttttc tatgacttct aatgtcattt gacaaaccaa atttcgatct gacttgggtc
    16201 tgaaagaaca agcacccttg cctttttatc taaataaacc tgacaccctt tgtcctcaag
    16261 gtaggtcttt agagcaagca agtcatagct atctgacacc tgaaattcta aaatctccaa
    16321 atcccatgtg acatgcggga caatcgtcaa atcttgacca gcctccctat taaactcaag
    16381 cgtgaccggc aggcaatcac caaaaataga ctgataaaaa gctctggatt gctcgtcatc
    16441 taaaacattt aagacaatca gatcaaagct aaactgactc agccccctaa agtcagcttc
    16501 cttgtcaatt gcaggaacat catcgacaat gtcaagctcc ttgatatcgt cctctgcatg
    16561 gagtaagaag cgatctccct ctggtgaggt gacttcaaag gcatagcctt tttttccctt
    16621 gaaaatcaaa tcatagtcaa cgccatgagc taggagctgc tcaatgtcct taggagcagt
    16681 tgttttgata acaattgtat ttactttctt agggccatct acaacgcgtg ttcttgctgc
    16741 tggagattct tcaattacaa agcgttcttg tccttggccc caagatgaaa aaattgatat
    16801 cgcgttttcc tctgacacta gccttaagcc tagatttttt tggtaaaagg caatattaag
    16861 gtcgcgattg ttaacacgta atactggggt tttaaagaca atattgtcaa ataaagtcat
    16921 atattcctcc taatcctctg ctattataga caaaattcca atttttgaca agaaattata
    16981 tgctttttaa ccgcctgtca cgcgctacca aggcaatata gcactcacag ccatcaccag
    17041 acttactagg tccaatcttc cttcgtgcgc tctatcacaa gcagctttcc ttagcgtaac
    17101 tcatgcacat attggtaaat gcgacttttt caaaatagca catgaagtac ccctttaatt
    17161 tgacttttcc ttaaccaaaa gcgagaacct tttttagttc tcacagtagc aatcacactc
    17221 ttgaaatgtg atttcgctct cctcaataac agatgataac tgaaattgcc cggattttct
    17281 tatccacgcg caacttcaaa agcaccttat cttcagcatt agtaaggata ctaccagctt
    17341 agctcagacc agattcagct ggctcttgct ggcaagcttt tatcacaaaa aagaaggcct
    17401 aagccttctt ttttacttga tataaaggaa tttgaatgct gctactgctg ctactgctgc
    17461 tagcactggg gcagcaaccg gtacccatga gtaccaccat tttgaatccc ccttggcttg
    17521 tccaaggact gattttggta agaaatggtg aaccaaacga gggcctaagt cacgcgctgg
    17581 gttgagcgct ggaccagtag gaccaccaag agaggtcaca agagtcatca ccaagaaacc
    17641 aatccccaag tgagctactg caagtgagcc tgtcacgtaa ggagagattt gcgttgcagc
    17701 tgttgtttgg tcatagccag cctctaccag cttaccaaca agctccacac caaagtaatt
    17761 cttggttaag gccattgcgc caaaaaagag gacaaaggaa ccaacaaact cgttcaaaaa
    17821 gccattaatg taggctgcct tacggctgcc cttgtcacca tcatcaactg ctgaaatcgt
    17881 tgagaaggat cccaaaatat tgttagggtt gtctgtctgc acaaaataag gcttgtacac
    17941 cgcaacaacc actaattggc caaacatagc ccctagcaat tgagcaagaa catattgtaa
    18001 aacgtgtgcc caagggaaca agcctgaaac tgccaagcca aaggtaaaag ctgggttaat
    18061 gtgatttcca gaaacgttac caaacataag tgccggcatc atcacaccga ggccatagcc
    18121 aaaggcaatc acaagccagc ctgagcggtt accctttgtt ccctttaagt caacattggc
    18181 aactgctcca tttcccaaaa taatcaaaaa tgcagtggca ataaactctg tgatgtattt
    18241 cacagtccat gttatttcca tattctctag tttcctccaa atgataagta taacagatac
    18301 cattttatca gggatactag ttcttgtaaa gcctattgta agatattgcc tgcttaatat
    18361 gtttacagtg ttttttcaca attacggaca actaataagt cttttttagc atgtcgcagg
    18421 atatactctg aggtcgatcc aatcagcaga cgctcaaagg tatttaagcc agttgctcct
    18481 accatgatca aatcagcctg ctccttttca ggtatgtcac tagctaagag ctttttaggg
    18541 ttgcctcttt cgatgatttt tttaatgctg ctaacgcctc tgcctctagc cattttctcg
    18601 taatagcgca acacctcctt ggcatgctcc tcttgtgtgt caaagacata atcactaacc
    18661 attgcatcac cctgataggc cttaacatca ataacatgag ccagcagtaa gaccgcatca
    18721 ttgcgaaggg caacattaat ggccttctca acagctaatt ctgattcgta agagccgtcc
    18781 accgcagcca gaatccgttt atatttgctt atcatctttg tctcctttcg ttgattagcc
    18841 tttatcaata gcctttgctt gtgtctttag gaaatacatg actgcgcagg cagctggaat
    18901 gagccctgcc agccagaaca attgatgaaa ggactgcaca ccagacccaa gaagcatatc
    18961 cttgatgagt cccaacagat aaggtcccgc acccaagccc aaatctagcc caatcatata
    19021 agtagacata gcggtattaa agcgatgctc ctcaaccccc ttgatggagg ctgcctgtcc
    19081 gcaggacata aaggttccat agccaaagcc tatcaaagca cccgaaagca gatagggaag
    19141 gctgcttgtc acactaccaa gcaggaaaag ccctagcgcc aaaaagagat agctgggata
    19201 aagaacccac tgctccccct taacgtccat caagcgtccc atagcaggtc gtgtgatcgt
    19261 aatgatcaag gcatatacca caaagaaata ggctcccacc gtcgtcaaat gaatgtctgt
    19321 tgtgtataat ttttgaaagc ctagcacaga agcataggca atccccatca aaaaggcaat
    19381 caaggtgata aataaggcct ttcgctcaat aaagctatca actgtccagg attttgtttt
    19441 tgccagctgc tctgagttga gggcaatatc tgtcacagga aaggcaaagg cccctagcac
    19501 aactactgcg atcaacacac tgcacaaaat aataatcatc cgaaaatcaa tgtgcaaatt
    19561 atccagcata aaggtcccaa caaaaggacc aatcgccgcc gctaggcttg ttgatagacc
    19621 ataaaaatta atcccctctc cgcgcttgct agctggaata taggcagtca caatggtatt
    19681 ggttgctgtt gagacaacac catagccaaa gccattaaac aagcgcacaa aatacatcat
    19741 gccaatcgtt ggcatgaaaa agtaggctag cgttgttagg agataaaaaa tggcgcctcc
    19801 tcttagcact aagcgtcggc caaaaacctc caattgcttg ccaaaaatca gtcgagccag
    19861 cagggttcct aggatataaa tccccgtcgc cagacctgcc tcactggtct tagctcctaa
    19921 ttccttagtc gcaacaaagg caatgatcac cgtaaacaag taatagacca tatacacaat
    19981 aaaatttaat actgtgatcc ctataaaatg cttgttaaat aatttgtctt ccactgaaaa
    20041 tgagctcctc cctatttcat taacatttta caaaaaaatc agataatgcc ccatttcaat
    20101 ggtataatat aggtgatact attaaacgac attagcaaat gctaagcatt gctgcagcaa
    20161 caaattatat aatgatacca gaaacacctc taggagaaaa gcgtgaacca tcaaatctta
    20221 cagcgttata ttgacagtca taactttcct attatcgaaa agggctacca caaatacctg
    20281 acctttgaaa gcttagagga ggattttacg tatatcctaa aggagggcat tgtcaagcaa
    20341 agcgttctgt caaaatatgg catggaattt aacctcaggt acgtcacagg ccttgagatc
    20401 acctctgtgc ttaatactgg ctattccaag gacatgagag agccctacaa tgttcgcatc
    20461 gaatctgaga ctgccagctt ttataaggtt cgtcattcca cctttttaag ggatattagc
    20521 gaggatatcg agctgcaggg ctatgtcaag gacttttatc actaccgcct ccaaaaatca
    20581 atgaaaaaaa tgcagtgtat gctgacaaat ggccgtatcg gcgctatctc tactcagatt
    20641 tacgatttaa tgaccctttt tggacgcccc ttggctaatg gccatatcct tattgatttt
    20701 atcatcacaa atgaggagct gggcaaattc tgtggcattt cgactgccag cagtgtcagt
    20761 cgtctcctaa agcagctcaa aaaagagggc attattcaaa tcaatgacca gcatatcatc
    20821 attaccaatt tagagaagct aaaggataat attgtttttt aacgatttag aaaggacgtc
    20881 ccatgcgcta taatcaattg tcttacattc ccaccagtct agaaacagct gtagctgagc
    20941 ttcaggccct gggctttgct gtccagcaag agcaagcacc caaggagaac ttcgctattt
    21001 tccttagaaa gctatttttt cattttcagg ataccgatta tcccttgagc catatgattg
    21061 caagcaagga tctcgaccta ttgacctttt taacatctga tgcaacactg acaaaagagg
    21121 tttttgattt agtggcctta caggtccttg gctttattcc tgctgttgac tttaccgatg
    21181 cacaggactt tatacaaaag attggctttc cgattgtttt tgacagccag caattactac
    21241 tcaatttaca tcagctgctt gcaacccggc agaagtccgg tgtgaccttg attgatagcc
    21301 ttgttagtca gggcttgctt cctatggata attgctacca ctacttcaac ggaaaagccc
    21361 tagcaacctt tgataccacc agcctcattc gcgaggtggt ctatgtcgaa gcgccacttg
    21421 ataccgatca agacggacag cttgacctca tcaaggtcaa cattatccgc cccaaggcca
    21481 gcactgctat cccaagcatg atgacagcca gcccttatca ccaagggatt aacgagaccg
    21541 ccaacgataa aaagctccat cgcatggaag gtgagcttag ccctaaggct cctcgtagga
    21601 ttaccgttga gccaactgat tttcagccgc ttgccaccaa gccctcaagg cttcctgtca
    21661 atgagtgcca agagaccttc agccatatca gctcctacac actaaatgat tattttctag
    21721 cgcgtggctt tgccaatctc tatgtctcag gagtgggaac agcaggctca actggcttta
    21781 tgacaagtgg tgactacgcc cagatcgaaa gctttaaggc tgttatcgat tggctaaatg
    21841 gcagagctac tgcttacacg agccacaagc gtgactatca aatcaaggct gattggtcaa
    21901 atggcttagt cgcaacaact ggaaaatcct atcttggtac catgtcaaca ggactggcta
    21961 caacaggtgt tgatggctta gcagtcatca ttgctgaagc tgccatttct tcttggtacg
    22021 attattatcg tgaaaatggg ctggtatgca gtcctggtgg ctacccagga gaggatctcg
    22081 atgtgctgac agagctcacc tactcgcgta acctgctgcc aggtgattac ttacgtcaca
    22141 acgaccatta tcaacagctg ctgagccaac aatctcaagc tctcgagcgc caatcaggca
    22201 actacaatca attttggcat gaccgcaact acctgccaca ggctgatcgc atcaagtgtg
    22261 aggtcgtcta cacgcatggc ctacaggact ggaatgtgaa gcctagacag gtctacaata
    22321 tcttcaatgc cctgcctgat agccttggaa agcacctttt cctacatcat ggtgagcatg
    22381 tctacatgca caactggcag tcaattgatt ttcgtgaggc catgaatgcc ctgctctgtc
    22441 aaaaaatgct aggacaaaat aatggcttta ccctaccaac aatcatctgg caggataacc
    22501 aaaaagaaca aacctggaaa gagctaacag cctttggcgg tcacagcaag cgtcagattg
    22561 ccctaggcga tgatcatgtc ttaattgaca atcactatgg cgaagaggac tttaagcgct
    22621 atagcaagga ttttcgtgcc tttaaagctg agctttttga aggcaaggca aatcaagcag
    22681 tcattgatat tctgttagaa gaggatctac caatcaacgg gcaagcctgc cttaagctta
    22741 agctaaaatc aagtgaaaac aaggggattt tggctgcaca gctcctagat tatggcaaga
    22801 aaaaacgctt tgctgatata cctgctattc ttgagctaga cagcattgac aacgggcagc
    22861 agtttgcacg tgaagcgctc aaggagcttc ccttcaagga cagcccatac cgcgttgtca
    22921 ccaagggtgt cctaaaccta cagcaccgca gcgacctatt gaccattgag gatattccaa
    22981 atgaccaatg gatgaccatc accttccact tgcagccaac catctatcat atggccaagg
    23041 gagacaccct aagagtcgtt ctttacacga ctgattttga gcatacaatc cgcgacaata
    23101 gcaactatgc cctaacccta gatttggagc aatcctatct cctaatccct actgatgagg
    23161 aggaataaat caaagcgcat caaaaaagcc tgagatcaca atgagctgca ccccaatcgt
    23221 tagatccttt gtctaactgt tggagtacag ctcaaagctc taggcttttt taactatttt
    23281 gaaacctttt taccagcctc agcaccagaa tgcaggctgt agacggactc gatatgaatc
    23341 aagcctgctg cctttggtgc gcccatcttg ccttctgccc attccttggc agcctcaaag
    23401 acaggaccct ctgtaatgat ttccgcacgc cctacaaagc gataaccacg caattgctcg
    23461 cgattgacat aagcgacctc aattttacca ttagcctgaa tattagagca ggtttggccg
    23521 ccagtatttt cattataaac caaggtttca tcgtctaaca gtctcatcga acgcttaggg
    23581 ccaatattag gattaccctc attatctaca gttactacca ttgctaattg ctcagcaatc
    23641 atttctttca tttcttctgt taacatataa tctcctctta atcgtttcta tagtcagctg
    23701 actacgcttt gattatagca cagttaagca gaaaagccga caaaaatagg ttagcttaaa
    23761 aaagttttac agtttactta agattagaat gattctcgct atctagccat cacccttgat
    23821 cacagtaaaa aggcgattag caagcaagca ctctttattt cataaaatcc gaatcgtcgc
    23881 ccaaaaaaaa tatcatcaac tgatatggtc aatgcctctg caatacctct taatttttca
    23941 tacttagctc gcctaagctt ttgcacatcc ttttcatatc tggctagtgt cctaacagaa
    24001 atcccagtta acgctgacag ttccttttgg gtcttttttt gagcaatcct caattccttt
    24061 aacgttgctt ttgacaatat tttccctccg cctctcatct caggtaatat taatgacaga
    24121 tgacaagttt attatagact tcggttttta tgaagtcaag tcttttatcg cactttcccc
    24181 acttcttttt ctaaatcttt tgatttagct tgatttgtgg tatcatatcc tatatagaaa
    24241 taaaggagaa tggaaatgtc cgaaaagaaa acattttttg caactaattt aaaatatctt
    24301 cggctaaaaa agaatatgga acaattagaa cttgctaacc ttttaggacg aaaaagctct
    24361 tcctcaatca gcgaatgaga aagaggaaag tacactccaa aatctggtct cctgagtgac
    24421 attgctgcca tctttgatgt cagcctgaca gacctcatgg aaaaggattt aacactggaa
    24481 aataagggag tgacttatca gcttccccaa agagatttag taatgatttc agagcagcta
    24541 tctgaaaaca attataacaa atggctggat tttggtcagg atctcttatc tcatcaggat
    24601 aaagaagaaa atcacaagcc aagcaaataa agagcctcac acgtcttatt ctcatcaagt
    24661 ttcgaaaaat cacctaccac tcaagcacac aaaaagcctt ggcagggctt ctaagcataa
    24721 gaaagctgta tcatatcaat acctcaggga ccatgatatg atacagcttt ttgtatctca
    24781 cttttagaca aggtagccac ataaagcttg cagatgacct acctctgtat tagctaccac
    24841 aaccaacagc tagctagact ggcaggccct ctataagcct cagcggatta tctaagcact
    24901 cccaacagct ccaacaaaat aaagacataa ccaataccat tatttaagat atgggctact
    24961 gttgaaaaat agatattctt cttccaaaca taaactaagc cgagcaaaag tcccagtcca
    25021 ccatacacaa cgatggaaga tagctcgctg aaggaataga tatgaaccaa gccaaatagc
    25081 aatgatgatc ccaacaatcg agccagcagc atacctgtgc ctgattggcc ctcaccgatt
    25141 aaaatcttgc ggaaaataag ctcctcattg aagggaccaa taatactcac caccagaata
    25201 aagatcactg tctcgaagcc ctcactagca ttatagcgat tagctaaaac agctgcattg
    25261 ctgctctctt ctaaaggaag gctactgagc aaaatatttg caacataaag cactgcaaaa
    25321 atgaccaaga cccacaaggt atttttgacc cattttgttg aaaactgccg ccagtccctc
    25381 tgataatctg ctcgataaag ccaacagatc ccaagtgcaa aaatcagcag atgtctcccg
    25441 taaaataaaa aggtattcaa taaaggcgga agctcaatca cattgctaac ttgtctataa
    25501 agatacacag caatgatata tagcatgacc agtacagctg cacgatgacg tttgatggta
    25561 tccaattact cttcctcaat tctaataatt gtcagattag ctaggctata ttgccatcag
    25621 ctaatcttga tcttaaatgt gactaattta caagcactca acttttgaat cggtaaagct
    25681 gacagacagc cctaccctag cttcaataaa gctatcttcc aatagtcctt gcgctcatca
    25741 gaactgtcaa aggcctgacc cagctgagtc aacagactta tccagtcaac atcacacaga
    25801 acaagaccat cttaccatat ccctgccaac tataaaagcc cctaacctga cctatttgac
    25861 tactaacagc aaaaaagcag cttaaaaaca ccaatcagac gccaccaagg actcttgatc
    25921 agcgcagctc gcacagacac ctgaaaaatg acagacaagc ctcttaaaag cacctcagca
    25981 agctgagcca acccttcaca gaatagacaa acaacaagag ctaagtcaag acctcaagct
    26041 agcagattac aggcagagac gcttgcaagg cttacccagc aaaaagcaac agactgataa
    26101 aggattcaca ccacacagcc acaagtcaag cagctagccc aaacaaagca ctgctcacca
    26161 aatcctacta tgctttctgg tagcccttat ccattcaaaa tcgtatccaa ggcttcttga
    26221 tattgcttgt ctcgcaattc tctgatcacc tgtgataaat actctgcctg atacatcaca
    26281 aagtcaaaat tgaaatccag aattttggtg ttctcattca atgacagcct ctcctcgata
    26341 aaagcagtca tctcagctgt tgtcacaatc aagtcaaaat cagttctcca aggcaattca
    26401 gcctctgaca aaatattaaa acgatagacc tttgcaacac aaggactcac ctgttgcatg
    26461 accaagctat ataaaatatc aatgtttttc ttgttgattt cgatcactgc tatggctaaa
    26521 ggtggcagac cttctctaac aagctgttcc agtcgcgtgc aaagcaaatg caaattagag
    26581 cctgtcagcc gaccaacacc agaaacccgc tctgcccagc tattaatcat cagctcgata
    26641 cgattggcca agagcttact gccttgatat tcctccgcat aataatattt ttgcgggata
    26701 aagagcgaca aatcaaacaa ggtcttacga aaataaggaa tcaaggtctg aatacaagcc
    26761 ttgtcaaagg cgatatagtg gccaaacaat tgacgcagct cacccagcag ctcttggtaa
    26821 gcaggatcct cctgaatgat cgtcaataag gccgaagaat cctcctcaga ccattgtgtg
    26881 atcgaaaaag agttgttaac cgtcaaataa acgagaaaaa tataatcaat ctcgctactg
    26941 ggaaagtcca tatcaagcaa caatttcccc tcacgcttga aaaagtcctc caaataccca
    27001 taaagcgcca aagactttaa gcgtttaaaa atcccctcct gaggaatcgc aacgtcaaac
    27061 tctccacgct tccaagatag cgacaagagc acatcaaaaa agcgaaactt cttatccagt
    27121 aacgggtgag gcgtttgttg ctttttgatc gaaaagataa agtcatgcac aatatccaga
    27181 tcatggtcag tcagctcata gatgacaatc ccgtacttat catgcaataa agcaatcaaa
    27241 tagcggatac gccactcctc accaacaaca ctattatcct ctaaggccaa gccgcactcc
    27301 tcaacaaagg gcttcatgtg ctgaatcagc cgataagctg acggtgtgga aataaaatgc
    27361 tccctagcaa agcctgagac agatttgacc ttatagcaag gtgccttgat caagagaaat
    27421 ttaagaatgt gcagccgtac cgattggcgg taaatcgtct tcaaaaacgg tttgcccctt
    27481 ttcaaaacgg tgcagcggac aatggtgcta tcccactcaa aggcgatatc tccttggaaa
    27541 agctcctcta attggtggat atagcgcttt atgttagcta ggctaaagcc cgtcttttgc
    27601 tgaatggcgt ggaaactgat ccttttttta ccaagtagta tggtcagcag caaagcctga
    27661 tgattaatca ctggttccaa atactcttca agcaaaacac tttctcctcc ttaaaccatt
    27721 tcgttagcgt cattatcata acaattttta ccaaaaaagt gatgaaaaat atttaatatc
    27781 aggacgattt ttctgatagc ctttattata acacaaaagc tcaaggcagg taaaacgata
    27841 aagaaatcaa cttaaaacta tgacacagtc tcatctcata tgatatagtt attcaggttt
    27901 cctaatggaa aacatattaa caacttaata atggagagaa gaaagttgaa aacaaaatca
    27961 tttagaaagg tactgacaac gtcagctacc tgtattgtgc tggcaacaag ctttgccgga
    28021 ggaaccctaa gagtctgggc agagcagctt tattatgggt ggaatgatgg aacgagacaa
    28081 agttcgccat attttttgta cgtatcgcct aaaaatgctc caaagcgtga attaaaagac
    28141 gagtatgttg tttattgctt taacaaaaaa ttgtattggc cagatcaatg ggaatctata
    28201 tacagcaatt ttaatgacat cagatctcca tataacgatt tacctgtata tgagaaaaaa
    28261 ctaggatatg atggtatatt taaacaatat gctccagatt acaaaaaaga tattagtgat
    28321 atcgcaagtg ctttggtggc agttttaagt aatggatacc ccactaacaa gtcacaacta
    28381 tcaactagct accatttaaa taatgattct tctagaaaag ttactcaatt agccatttgg
    28441 tattttagtg atagtttaac aaaagaatac cttaaagata cgggtggtta taacttaaac
    28501 gatatggaaa aaaaagcttt agatttttta atcagtaaag gagaggattc taagcttaaa
    28561 tcagagcaga gtaattactc attggatatt tatgtttatc aaagtggcgg gcatgaccat
    28621 atgaaagatt accaaaatct tctcggctct accttaattc ctaaagaacc gctaaagcct
    28681 cagctaggtg gttttagtgg acataatgga aatggattaa gcggccttga aggaggatca
    28741 tcaggttcac aagaaactaa tgaagatggt aagaaaggac ttataggttt ccatggagga
    28801 ctctcaggaa gcgagggcaa acgagatcct ttccaggatt gaagggtgag gctggtgcac
    28861 ctgatacacc tcaaaagcct aatgacccat tgcaaagtct tgaaggtggt aactctccta
    28921 tcgtagaaca aaactatggt agtactgagg gatatcatgg tcaatctggc attcttgagg
    28981 aaaccgaaga cactaaccca cctggtatca ttttaggtgg ctcaggaaat gtcgaaacga
    29041 gatcctcatc tgatggggct tggcggtggt ctagctggcg aatcaggaga aacgacacct
    29101 aaaccaggac agactggtgg tcatggacca atcatcgaga caacagagga cacacaaaaa
    29161 ggcatgtctg ggcaatctgg cggcactatc gagtcagaaa acaccaaaaa gcctgaggtc
    29221 atgattggtg ggcagggaca aaccatcgaa acaacagagg acacacaaaa aggcatgtct
    29281 gggcaatctg gcggtactat cgagtcagaa gacactaaaa aacctgaggt catgattggt
    29341 gggcagggac aaaccatcga aacaacagag gacacacaaa aaggcatgtc tgggcaatct
    29401 ggcggtacta tcgagtcaga agacactaaa aaacctgagg tcatgattgg cggtcaggga
    29461 caaatcatcg acttctctga aaacacgcaa tcaggtatgt ctggacagtc tggagacact
    29521 acggtcattg aggataccaa gaagtctgag ataatcattg gtgggcaagg acaaatcatc
    29581 gacttctctg aggatactca gccgggtatg tctgggcaat ctggaggcac cacaattgtc
    29641 gaagacacca agaagccgac acctaagcct aaacctgcac ctgcgccaat tgttaatgac
    29701 gaaaaaccta acaaaggcac tcagctccca cagacaaatg atatgaagca actcacccta
    29761 agcatcatcg gtgcaatgtc aatgctgctt gtcctatgtc tgtctctatt caagcgacca
    29821 tctaaaaaag actaagcaac actgacaagt gatcattatt gtacggacgt ttacaggcgg
    29881 gctttctgcc ctcttaaaac accgtacaac aacaaaacgg tctaaataga aatatccctc
    29941 aagggttaga caatcgctct agcccttggg gctttttttg atacttataa tagaagagag
    30001 caagcagtga cactttcttt ttgccctata tctgctaaca ctagcggtat gtgcagttac
    30061 cataggctat caactcgtcg tgcaactcta gagaaaagct gatacaaaaa acaagcacca
    30121 gccttgctgc tgatgcttgc tccggactta ctgataagcc tttgtgatgt cctagcttta
    30181 taaccatatg cctattacct aaaggtctag tctcctaatg gtgggctggc tggtaaaagc
    30241 aaggagaaac agctcccctt tccaagctgg ctctcaacag caatatcccc acctagttgg
    30301 cgagctaact gcctagcaat agagagcccc agcccatgac caccagtctt catattgcga
    30361 gaggcctcaa cacgatacag gcgcttgaaa atcaaaggca ggtcctcttt tttgatccct
    30421 tgcccctgat caataacatc aatgcgaatg gactgctcct gttgataagc atgaatcgtc
    30481 aaagccgtat tagcctttga atatttaagc gcattgctga ctaaattcag cataatccga
    30541 gacaaagcat catatcggct gctgatctta accacctctt ttgccacctc aatatgaacg
    30601 gagcgttttt cctgctctaa ggtcaattga aattcggata gcatgtcaat caatagcttt
    30661 tcaagataga tgatttgaag ctgctgcttg tcgtcttgct tttgatcatt taagctgacc
    30721 atatgcaatt cttcaactaa ttgattcaaa cggttggtct gtcgtgagat ggtgtttaga
    30781 tagtgccttt cctcttccct tggaataacg ccatctaaaa tcccctctac agttgcttga
    30841 atagaggtca agggtgtctt aatatcgtgc gacagctgag caatcatcat ggatttctca
    30901 tgctcactct cactcaatga ctcaaagctg acctttagct ctgaggacat ctgattaaag
    30961 gcttcctcta gatctttaaa ctccaaagga cacttgatga gctgaccact atcaaagttt
    31021 ctttcagaaa tagcctgtat ctttttcttt agccttttaa gcgatgaaaa aacattactc
    31081 aaaaggatca tattcacaat tcctccggct actgaagcaa ttagagctat tactaaaata
    31141 tatgaaatat cctcaatggt aatgagcatt tggtttaacc caacaatcag gcctgcaata
    31201 gtaatcagca tagacattaa atagccaatg acaatgtacg ttcttaatcg catgctaccc
    31261 ctctaattta taacctagtc cccaaaccgt tttaatggtt ggtgtttgct cggtactgta
    31321 ttttgccaag tcattgcgta gggaatgaat gtgaacattt aaggtattgg tatcatctaa
    31381 atactcctcc tccca
//
LOCUS       DARYXW010000012        31167 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.012, whole genome shotgun sequence.
ACCESSION   DARYXW010000012 DARYXW010000000
VERSION     DARYXW010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31167)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31167)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31167
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.012"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            223..795
                     /locus_tag="TV191_000462"
     CDS             223..795
                     /locus_tag="TV191_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase"
                     /protein_id="HEL1507006.1"
                     /translation="MKKRLAFILVAFGILGFSLGNEVLAADTAPASATMATDSDVSFY
                     NGELLKKYLVQSGDRLYFDYDKAIQDKVSDGVIDMGFLVETISEDYSQQTFTSRKYFK
                     AGWQLYGNYCGPGHNGNHFTLPVIDVLDQGCQNHDSCYRWGAGIGANCECNRQLVNYI
                     KVYRRWMPAHALGVADAIRVYFETVGAIGC"
     gene            789..1079
                     /locus_tag="TV191_000463"
     CDS             789..1079
                     /locus_tag="TV191_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507007.1"
                     /translation="MLTLKNIINRYYMYYVFLIVVIWIGMFFVRWDTTVAGVLLYPLI
                     MKQVFIVLGVVAMIMAIISRKIVLGIFGLLCCAAFWINLFLAFYLLPGLLGN"
     gene            1765..3036
                     /locus_tag="TV191_000464"
     CDS             1765..3036
                     /locus_tag="TV191_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEL1507008.1"
                     /translation="MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGD
                     NEERLLSVIDIASQRSDLVILCGGLGPTDDDLTKQTLAKYLGKALVFDEQAGQKLDAF
                     FAHRKQAARTPNNQRQAQLIEGSIALQNQTGLAVGGLITVDRVTYVVLPGPPSELKPM
                     VKNELVPLLSASHASLYSRVLRFFGIGESQLVTALEDLIKHQTDPTIAPYAKTGEVTL
                     RLSTKADNQALADERLNRLEAQLLSIRTVDNQPLRRLLYGYGEDNSLARETFELLKRS
                     GKTITAAESLTAGLFQAQLTDFAGASQVFNGGFITYSIEEKARMLGIPLGELQRHGVV
                     SSFTAEQMAAQARCLTNSDIGIGLTGVAGPEALEGQPAGTVFIGLATKNKVESLKVVI
                     GGRSRLDVRYIAALYAFNMVRKTLLKSENLL"
     gene            3130..4266
                     /gene="recA"
                     /locus_tag="TV191_000465"
     CDS             3130..4266
                     /gene="recA"
                     /locus_tag="TV191_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEL1507009.1"
                     /translation="MAKKVKKNEEITKKFGDERRKALDDALKNIEKDFGKGAVMRLGE
                     RAEQKVQVMSSGSLALDIALGAGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDNHVGLQARMMSQAMRKLSASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGTTQIKGTGDQKDSSIGKETKIKVVKNKVAPPFKVAE
                     VEIMYGEGISRTGELIKIASDLDIIQKAGAWFSYNGEKIGQGSENAKRYLADHPELFD
                     EIDHKVRVKFGLLEDTEESAAADTVAAKADELVLELDDAIEIED"
     gene            4642..5040
                     /gene="spx"
                     /locus_tag="TV191_000466"
     CDS             4642..5040
                     /gene="spx"
                     /locus_tag="TV191_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEL1507010.1"
                     /translation="MIKIYTISSCTSCKKAKTWLNAHKLPYKEQNLGKEPLSREEILA
                     ILSKTENGVESIVSSKNRYAKALNCDIDELSVNEVIDLIQDNPRILKSPILIDDKRLQ
                     VGYKEDDIRAFLPRSIRNIENAEARLRAAL"
     gene            5153..5422
                     /locus_tag="TV191_000467"
     CDS             5153..5422
                     /locus_tag="TV191_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEL1507011.1"
                     /translation="MGFTDETVRFNLDDGDKKQISETLTAVYHSLDEKGYNPINQIVG
                     YVLSGDPAYVPRYNDARNQIRKYERDEIVEELVRYYLQGNGIDIR"
     gene            5419..5838
                     /gene="ruvX"
                     /locus_tag="TV191_000468"
     CDS             5419..5838
                     /gene="ruvX"
                     /locus_tag="TV191_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEL1507012.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIRINEDKQDFGFDR
                     LAELVKQYQVDRFVIGLPKNMNNTSGPRVEASKAYGDKIEELFHIPVSYQDERLTTVE
                     AERMLIEQADISRGKRKKVIDKLAAQLILQNYLDCNY"
     gene            5848..6147
                     /locus_tag="TV191_000469"
     CDS             5848..6147
                     /locus_tag="TV191_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEL1507013.1"
                     /translation="MTHNHDHEHEVITLVDEQGNEALFEILLTIDGREEFGKNYVLLV
                     PAGSQEDESGEVEIQAYSFTENEDGTEGDLQPIPEDSDAEWDMIEEVFNSFLDEE"
     gene            6695..8254
                     /locus_tag="TV191_000470"
     CDS             6695..8254
                     /locus_tag="TV191_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2079 domain-containing protein"
                     /protein_id="HEL1507014.1"
                     /translation="MSQLHQEVMLEKVNYLVKDHPSSHTTKYDMKVPSLYKFYIFFFS
                     IIASLLTVAVPFFADTANSVQSQNLYIGMMLTKGQIPYSDLFTTGGFLFFVLIALSYH
                     LGTTVWLVLVQALCFYLTGVYFYKLIHYVTGIQKVALGFTAIYYLLSISLGFGGLYAI
                     QLALPFVLVSLWFLTKYFAGLVKDEAFILFGFAAAIAMLIEPRTLLFWLLACIAIIAY
                     NVSQKHFARGFYQLLAAIFGMLLVFYTAGYFILNLQILSPYLEQALVYPFSYFVTGDL
                     SLILGLTVQLGLVLGLGLLTGLLTFMKQPKLESDLAMKWLLVFVVFSYAGIAAISHDF
                     HTYHLLPLLPYALILLSSSVGRQYEAGLRMVSHRRRKGKNGARRVIAIYLNKHFYVPA
                     IIMLGAVFGTAYQYVTSSAINQERSQIAHYLRQRLTEDQPIYVWDDTSKIYLETQAKS
                     ASQFASPFVNLKKESHQQMLEDELLQNKAVYIVVNKQKALPKAVKKIVTANYKIDRKI
                     DVKGFSLYQKK"
     gene            8351..10549
                     /gene="nrdD"
                     /locus_tag="TV191_000471"
     CDS             8351..10549
                     /gene="nrdD"
                     /locus_tag="TV191_000471"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011529096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEL1507015.1"
                     /translation="MITLEKDKVIVQPAIKVIKRDGRLVNFDATKIYSALLKASMKVT
                     RMSPLVEAKLEAISERVIAEIIERFPTNIKIYEIQNIVEHELLAANEYAIAKEYINYR
                     TQRDFARSQATDINFSIDKLIHKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLKL
                     LPAHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLANGFKIGNAEVESPKSIQT
                     ATAQISQIIANVASSQYGGCTADRIDEFLAPYAELNFKKHMADAEKWVIEELRESYAF
                     EKTKKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSWFEREIQKAILTIRINGL
                     GSEHRTAIFPKLIFTVKRGLNLEPDSPNYDIKTLALECATKRMYPDMLSYDKIIELTG
                     SFKSPMGCRSFLQGWKDEQGQDVTSGRMNLGVVTMNLPRIAMESNGDMDKFWELFNER
                     LHICKDALVYRVERVKEATPANAPILYQYGAFGKRLAKTGNVDELFNNRRATVSLGYI
                     GLYEVATVFYGGQWEHNQEAKDFTITIVKEMKKACETWSDEYGYHFSVYSTPSESLTD
                     RFCRLDTDKFGVVADITDKEYYTNSFHYDVRKNPTPFEKLDFEKAYPAAGASGGFIHY
                     CEYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDKCYECHFEGDFTPTERGFTCPNCG
                     NNDPKTVDVVKRTCGYLGNPQARPMVNGRHKEISARVKHMNGSTIKYPGI"
     gene            10655..10801
                     /locus_tag="TV191_000472"
     CDS             10655..10801
                     /locus_tag="TV191_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507016.1"
                     /translation="MGKYQLDYKGMQQVERFHEKHSVAKTDKKSRVQQLRAQFLEKAK
                     QSKK"
     gene            10829..11764
                     /locus_tag="TV191_000473"
     CDS             10829..11764
                     /locus_tag="TV191_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEL1507017.1"
                     /translation="MLDIGIVGLGAISQKAYLPYMRQLRGINWHLSTRNALVRQEVGQ
                     LFGCARLYSTVNELLEAKLDGVFIHAATKAHLELASLFLQKGIPVYMDKPLTEDFFST
                     QALYQLADKHNTFLMADFNRRFAPGVKKLSTLSTKRKVVVEKNDINRPGDKQFKLFDF
                     FIHPLDTALFLVDRRLVAGYFHYQLTDNDLLSQVSVTLRTEQTIISAAMNLQSGSRRE
                     VMEVQTPKETYHLENLETLRAYRGVDQEIKGFSAWDTTLSKRGFEAIVDSFLQAVKDG
                     VNPVKPETSLLSHWICHQICQSHEADGILDVSLPL"
     gene            11777..12271
                     /locus_tag="TV191_000474"
     CDS             11777..12271
                     /locus_tag="TV191_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1507018.1"
                     /translation="MKLRRPKKQDEASVLEMMAEFEDYQSPHDGGFWNAEHFDYEKWL
                     ESNALMEAGLAIPENWVPAIQLVAFADQQAIGFVNVRLRLNEQLLVKGGHIGYSVRPS
                     QRGKGYAKLMLKEALQLARQKGIREVLVTCHCSNSASRSVILANGGQLKDCNKGIERY
                     WIKA"
     gene            12281..12895
                     /gene="nrdG"
                     /locus_tag="TV191_000475"
     CDS             12281..12895
                     /gene="nrdG"
                     /locus_tag="TV191_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEL1507019.1"
                     /translation="MKENCWNSPKPKEWTSEALSQGRVIDYKAFNFVDGEGVRNSLYV
                     SGCMFHCKGCYNAATWSFKAGIPYTKELEEQIMTDLAKPYVQGLTLLGGEPFLNTGIL
                     IPLIKRIRKELPEKDIWSWTGYTWEEMMEETQDKLELLSMIDILVDGRFDITKKNLML
                     QFRGSSNQRIIDVKKSLAAGEVVIWDKLNDGDQSFEQMSRDDLI"
     gene            complement(13353..14084)
                     /gene="yaaA"
                     /locus_tag="TV191_000476"
     CDS             complement(13353..14084)
                     /gene="yaaA"
                     /locus_tag="TV191_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEL1507020.1"
                     /translation="MLTFLIPTAKEMKPVPPCYPHQLPQKSLPILEAMAELSLEELAR
                     AYSIRIEAASKEAKRLKAIAQGQSSAYPAYQLFNGLMYRHLKRDNLSKDQQDYLSKQV
                     YITSSFYGIIPTDEKIAEHRHDFHTKVTINGQSLKHYWRPIYDQFAKDHKQIISLLSN
                     EFRDVFSKEYQKLWISPKFMEERSGQLKTHSTISKKARGAFLTACLENNVQTKEALKQ
                     LSFAGFCYNEELSTETNYYYIKKES"
     gene            14520..14723
                     /locus_tag="TV191_000477"
     CDS             14520..14723
                     /locus_tag="TV191_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1507021.1"
                     /translation="MENRIQELRKSRGISQADLADMMCVTRQTIISLEKGRYNASLEL
                     AYKLATFFNLTIEDVFLFEEKGE"
     gene            14725..15178
                     /locus_tag="TV191_000478"
                     /pseudo
     CDS             14725..15178
                     /locus_tag="TV191_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516426.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            15188..15862
                     /locus_tag="TV191_000479"
     CDS             15188..15862
                     /locus_tag="TV191_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEL1507022.1"
                     /translation="METKHSAVKVIISKLKWFGLALLVFMLEQAPTFLITKEQPMWQT
                     LLLVVIFLLISGGTYYLAVKLHIVGDQAIPKNDYRALWIGLGVVAVFVVKMIGGILLF
                     LEHGPGANTVNQAALEQAGLSPILMVTLVAIVAPIVEEIAFRGLLYGKLFGAESYLGL
                     IFSSIMFGLIHVPTDFGSWFIYGGMGLVLGFVFHKTKKVEYTILIHFLNNALAVLIML
                     LLPYLQ"
     gene            15892..16329
                     /locus_tag="TV191_000480"
     CDS             15892..16329
                     /locus_tag="TV191_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507023.1"
                     /translation="MKNDRWIDKKYQRWEKVYKRLGHSLLTIGVLVGTYGIFLIIQGN
                     HQTGFLLFILGPILLIASCLCYYVFTEPTSLREYLINSYDERNRAIRQKAQAYCFCLF
                     AFLFLMLAIFFPNMTIKELFGYNLPLIVFNLYVMIRAWVSKHM"
     gene            complement(16552..17325)
                     /locus_tag="TV191_000481"
     CDS             complement(16552..17325)
                     /locus_tag="TV191_000481"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEL1507024.1"
                     /translation="MKIGFIGVGKMATAIIQGLTHTPHELIISGSSLARSKEIAGQLH
                     LSYAQSHQELIDQVDFIILGIKPQLFETVLSPLQFKQPIMSMAAGISLDRLAQLTSSH
                     LPLLRIMPNMNAQILQSTTALTGNDLVTADLLATAKELTNSFGTTFEIAEKDFDTFTA
                     LAGSSPAYLYLFIEAMAKAGVKNGLPKDKALSIVSQTVLASAKNLLVSTDSPHDLIDK
                     ICSPGGTTIAGLMDLEKTGLTHSVCSAIDTTIKKAKDLS"
     gene            complement(17409..18476)
                     /gene="pepA"
                     /locus_tag="TV191_000482"
     CDS             complement(17409..18476)
                     /gene="pepA"
                     /locus_tag="TV191_000482"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEL1507025.1"
                     /translation="MIDLFSKIKEVTELDGIAGYEHTVRDYLRAKITPLVDRVEVDGL
                     GGIFGIKESKADQAPRILVAAHMDEVGFMVSEIKADGTLRVVEIGGWNPLVVSSQRFT
                     LYTRAGQAIPVISGSVPPHFLRGANGAASLPAVSDIVFDGGFTDKTEAESFGITPGDI
                     IVPQSETILTANKKNIISKAWDNRYGVLMVTELLEALKDQTLHNTLIAGANVQEEVGL
                     RGAHVSATTFDPELFFAVDCSPAGDIYGNPGHIGDGTLLRFYDPGHIMLKNMRDFLLT
                     TAEEAGVAFQYYCGKGGTDAGAAHLKNGGIPSTTIGVCARYIHSHQSLYALDDFVEAQ
                     AFLQAIVKKLDRSTVDLIKKY"
     gene            18821..19168
                     /locus_tag="TV191_000483"
     CDS             18821..19168
                     /locus_tag="TV191_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEL1507026.1"
                     /translation="MAEIVSFCSSLLFPFCDKMKGMNGKKTRIVSGLIGLGLLAGLGL
                     RLKEVYQERERQRVLVELRAFFSALGEIEVLYINSFSSKRDDVTGGLVMTDGKTYTYH
                     YHKGSIDFKEDLT"
     gene            19165..19482
                     /locus_tag="TV191_000484"
     CDS             19165..19482
                     /locus_tag="TV191_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEL1507027.1"
                     /translation="MIIPTSKEELARLIETEPRLVLFFTADWCPDCQYIYPVMPELEA
                     ENPDMTFVRLDRDDFIDLAQDWQIFGIPSFLVMEKGQEKGRLVNRLRKTKAEISDFLA
                     AYH"
     gene            19497..20123
                     /locus_tag="TV191_000485"
     CDS             19497..20123
                     /locus_tag="TV191_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEL1507028.1"
                     /translation="MIFAYNKEQVGDVLMVILEDKKDIKRQVERKGRVARVFAEETGQ
                     TLAWNIFEASALIAVEGNGQVFLSEEELAILNAELAQEGFTERLEASPAPVFVVGQII
                     EMIPHPDSDHLNICQVQIAPDKAVQIVAGAPNAAVGLKTIVALPGAMMPSGSLIFPGK
                     LRGKESFGMMCSPRELALPNAPQKRGIIELGDAAAVGEAFDPAKHWQS"
     gene            complement(20426..21139)
                     /locus_tag="TV191_000486"
     CDS             complement(20426..21139)
                     /locus_tag="TV191_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1507029.1"
                     /translation="MTINLKAYQDMLTRPWGKLMYDLIFAQLGPIAGKTILDFGAGFC
                     ITAEALAVQNEVTAIEPNPDLLFAQKQESIHKIKGSLEALEKLPDQAFDMIICHNVLE
                     YIAPKEHAIYLAQMERLLKPKGQLSLIKHNQVGKVLHSVIFEHDYDKALNVLNGQAFE
                     SLSFAAGQTYSIDDLLRKTDLKLQGYRGLRTCYGLQPNEVKAKPDWLEVLRTIELAIC
                     DQKPYKDMAFFQHVTLSKA"
     gene            21251..21646
                     /locus_tag="TV191_000487"
     CDS             21251..21646
                     /locus_tag="TV191_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL1507030.1"
                     /translation="MYNKVILIGRLVAKPELNKTLTDKQVVRFTLAVNRRFKTTTGER
                     EVDFINAVAWGGLAETLASYASKGSLLSLDGELRTRKYDKAGQTHFVTEVLCHSFQLL
                     ESRAQRAIRENNAANDLIDLALEEEKLPF"
     gene            22093..23067
                     /locus_tag="TV191_000488"
     CDS             22093..23067
                     /locus_tag="TV191_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL1507031.1"
                     /translation="MRFKQLSLTAFIGLLAMLLTACRQETNQTHQAARVGIIQYAEHS
                     ALDAAREGFIEALEQGGFREGKNLTITTKNAQGDQANLQTMVEQLAGKNDLQLAIATP
                     AAQALLNMDSETPAVFTAVTDPVSAGLVDTLAKPGGNMTGSTDATDVENQIDLLTKAL
                     PQARTVGIFYNSSEVNSEIQAKKAKRELEKKGLKVLMKTVTTTNDVQQVMTSLASQVD
                     AVYLPTDNTVASTATTIGDILKEAKIPSMGSDAAYLSAVLFTSGVDYHAIGMQAGQQA
                     VDILKGKKPASIQVAKPQKASIAVNDDMARLLGIDPEVIKALASNGAN"
     gene            23085..24047
                     /locus_tag="TV191_000489"
     CDS             23085..24047
                     /locus_tag="TV191_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL1507032.1"
                     /translation="MKKGSYLILLVLAGFVLVACRSTASPRKVNQSHVNIGILQYMEH
                     DSLTAARRGFEAQLKAAGYTKGDKLSLHYQNAQGDQANLQTISEQLVKQNDLILAIAT
                     PAAQALATVSSDRPIVFTAVTDPISAGLVDRIKKPGGLITGTSDQAPIAKQIDLLAQA
                     LPEAKTIGILYTASERNAEVQVKEAETLLTKVGYRVIKKGIATSNDVQDTAASLMRAV
                     DALFVPTDNTVASTMTMLGELSLANKVPIIGGSTDMVDAGGLLTYGIDYESLGRQAGE
                     MAIKILRGQDPASLAVEYPKTVKLHINQAMADKLAIDTSTLSVD"
     gene            24162..25046
                     /locus_tag="TV191_000490"
     CDS             24162..25046
                     /locus_tag="TV191_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1507033.1"
                     /translation="MSLILSSLSQGLLWSIMAIGVYLTFRILDIADLTAEGSYPLGAA
                     ICATGIVSGVSPLLATFLAFIGGLLAGLVSGLVHTKLKIPALLTGIITLTGLYSVNLK
                     VLGRANVALLRQRTLVTQLYDLGFTKLAAVLIMGFVFVTIVIFLLALLMKTQLGLALR
                     STGDNNPMSEANGIKTDQMKIMGYMLSNGLIALCGALLCQNNGYADLNAGVGTIVIGL
                     ASIIIAEVMIRQLSIGWRLASIVLGSIVYRLIILAILAIPGMDADLVKLFSAMLLAAV
                     LFVPELQQRLRLRKTSLG"
     gene            25055..25858
                     /locus_tag="TV191_000491"
     CDS             25055..25858
                     /locus_tag="TV191_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1507034.1"
                     /translation="MSAILSIKAIHKTFEAGTINENHVLRGLSLDIEEGDFISVIGGN
                     GAGKSTLMNTLAGTLAFDQGDILLEGKSIKHLSAAKRAKDISRVFQDPKMGTASRLTI
                     EENMAIAYRRGKSRGLGWGVKERERQIYRQALQELGLNLENRLKAETQFLSGGQRQAL
                     TLLMASLAKPKVLLLDEHTAALDPKTSTMVMALTKQLVETHGLTTLMITHNLENAIAY
                     GNRLVMLHQGNIVVDIKREEKAKLTVDHLMALFHQNSGHTLLDDALVLG"
     gene            complement(25957..26961)
                     /locus_tag="TV191_000492"
     CDS             complement(25957..26961)
                     /locus_tag="TV191_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507035.1"
                     /translation="MLSRHNIVQRSLVKHLLLLATLLGSLGLGNSLSKADSQDHLHVN
                     LYLIQSDSNLKRYGKRIIDKAIEKVKARPRLKFSSEYEVNQFLNNISRLHPELRLTEQ
                     ETQSNKQQTPSKETRRAEASRNSNTSRPAASLSSYRRYSDAQILANIKAELEKSDYDA
                     IKQFKDDFINRLHSQEIQLNPYRDSSKIPALLFRELQYYLKLHPEMIYHLDGINLSPE
                     VADSFVSRLANAYSLDNMLSILQEARAYGQGIIDTIAKRAEAKAILTEHKNTYKDRNQ
                     RVSEDYYSTAFHEIDEAITIQQLNKAIEIVENEAYRIRNKSFDYNRRHHGFITLRKIS
                     "
     gene            complement(27247..27888)
                     /locus_tag="TV191_000493"
                     /pseudo
     CDS             complement(27247..27888)
                     /locus_tag="TV191_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635233.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
     gene            complement(27909..28886)
                     /gene="dusB"
                     /locus_tag="TV191_000494"
     CDS             complement(27909..28886)
                     /gene="dusB"
                     /locus_tag="TV191_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEL1507036.1"
                     /translation="MTRLNSPFRIGHVEIPHRTVLAPMAGVTNSAFRTIAKEFGAGLV
                     VMEMISEKGLLYNNEKTLHMLHIDDNEHPMSIQLFGGDAEGLKRAADFIQSHTKADIV
                     DINMGCPVNKVVKNEAGAKWLRDPDKIYHIIQEVTSVLDIPLTVKMRTGWADSSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGTCDHETLARVSRAITRIPFIGNGDVRTVQDAR
                     FMIEEIGVDAVMIGRAAMNNPYLFTQINHFFETGEVLPELPFAKKLDIAKDHLKRLIR
                     LKGEAIAVREFRGLAPHYLRGTAGAAKIRSAVSRAKTLAEVETIFAQIH"
     gene            complement(28873..29745)
                     /gene="hslO"
                     /locus_tag="TV191_000495"
     CDS             complement(28873..29745)
                     /gene="hslO"
                     /locus_tag="TV191_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEL1507037.1"
                     /translation="MDKLIKTISASGAFRAYVLDCTETVRYAQERHHTLSSSTVALGR
                     TLIANQILAANQKGDSKVTVKVIGDSSFGHIISVADTKGHVKGYIQNPGVDIKKTATG
                     EVLVGPFMGQGHFVTITDYGTGNPYTSTTPLITGEIGEDLAYYLTESEQTPSAVGLNV
                     LLDQEDKVKVAGGFMLQVLPGASVEEISHYEKRIQEMPAISTLLASENHIDALLAAIY
                     GEEPYKRLAEEQLSFQCDCSRERFASALMSLPKADLLTMLNEDKGAEIVCQFCGTKYQ
                     FDQTDLEVLINDKA"
     gene            complement(29995..>31167)
                     /locus_tag="TV191_000496"
     CDS             complement(29995..>31167)
                     /locus_tag="TV191_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HEL1507038.1"
                     /translation="HNLSQLPVLVLSQNLELLQAYDDEERRFPYYELIKTLDIPSNTE
                     LTCYEGTLEESSLMFPIGDKFIFIGPFYTSFFQDSYKEELADSFLKRYPDKSKKELVG
                     YISTIPHFPASHIRSLLIAVDAFFDTNFEMSCQQSINDLLEEAQLIWEDPHIIANLEL
                     ENTPSFHVPAVLNYLNHIIDLVKLGNTELLKHEINCIPSSDVVSSSIPALRAEKNLSI
                     IYFIKLLELSFTENTDVAKNYERIKHFMNLTEKATDLLKVLQIRAAAIISLSESLTNK
                     SVSDKQQIYNSILYYVDKHLYSKLKVSDIAKHLYISESHLRAVFKMYSSISLQTYILK
                     EKVQEAKLLLRRGVPAGEVAKLLYFYDTTHFLKTFKKYTDTTPHDYLAHYQQSITK"
BASE COUNT         8922 a         5566 c         7189 g         9490 t
ORIGIN      
        1 aagagtaaag gaggaaaatt tatgaggaga catctaaagg ttgtattatt acttgcagca
       61 ctattggcat ttattgtaaa tgagggtaat tttccatggt ggccttgggg accatagtac
      121 ttaactgatt actgttatgt tgttgccatt agactatcta gattaatcaa agagtaaaat
      181 acaagtagct tagtgaaaga cattttaaga ggagaaaagc atatgaagaa acgtttagca
      241 tttatattag ttgcttttgg tattttggga tttagtttag gaaatgaagt tttagctgca
      301 gatactgcac ctgcaagtgc aactatggca acagatagtg atgtgagttt ttacaatgga
      361 gaactgttga aaaaatattt ggtccaaagt ggtgatagat tgtattttga ttatgacaaa
      421 gctattcaag ataaagtttc tgatggtgta atagatatgg gattccttgt tgagacaatt
      481 agtgaggact attcacaaca aacgtttacc tctcgaaagt atttcaaggc aggatggcag
      541 ctttatggta attattgtgg acctggccat aacggaaatc attttacttt acctgttatt
      601 gatgttttag atcaaggctg tcaaaatcat gacagttgtt atcgatgggg agctgggatt
      661 ggtgcaaatt gtgaatgcaa tcgtcagtta gtaaattaca ttaaagtata tcgacggtgg
      721 atgccagctc atgccttggg ggttgctgat gctattagag tatattttga aacggtaggt
      781 gctattggat gttaacctta aaaaatatta tcaatcgata ctacatgtat tatgtattcc
      841 ttattgttgt gatctggatt gggatgtttt ttgtacgatg ggatactact gtggctggtg
      901 tattactcta tccactgatt atgaagcagg tatttatcgt actaggagta gttgcgatga
      961 taatggccat tatttctaga aaaattgttc ttggaatttt tggtttacta tgctgtgctg
     1021 ctttttggat taatcttttc ttagctttct atctattacc tggacttttg ggaaattagc
     1081 gattaaactg tttttgatgt tttgaagatg agaaacagat tgtttttctg taaggcttcc
     1141 tgttacttct caaatgcttt ggagtatctc tttatcattt gttcactgtt gacaacgtta
     1201 aaaagattat tccaaacatg ggaattgctg cttcagggta ttccttgtta atattggatt
     1261 gattagttgt tatttatgca aaatccttag agcattgctt tctcattctt ggttcatttg
     1321 aataaaatgt aactaaaaaa actttgtaat caattcaaat tgtcacaagt ataaaagtaa
     1381 aaaagcgact ttgttagtga tctgatattc ggaagtccta tcattgctcg ctttttgttt
     1441 tttgaggttg atttttattc cgaaattgtt gtgaataagt gcaattttaa gctaagaatt
     1501 acctaaaatc ttttgaagat tactgcttag cttctaatac ctatttatcg gtgtgttgat
     1561 aattggagag atagcgggat tgtcatatga aataaatttt agaaaattta aacaagttat
     1621 tctgattatt attatttcaa cataagtctt tatttgatta tcattgaaaa ccattaattc
     1681 atctaaaatt atttcaatgc ttcatggatg attctttttt tgttaaaatg agattgaatg
     1741 tcgaatagat aagtaggtgg gaaaatgaaa gctgaactca ttgcggtggg aaccgagatt
     1801 ctgactggtc agattgtgaa taccaatgct caatttttat cagaaaaaat ggcggagctt
     1861 ggtattgatg tttattttca aacagctgta ggagataatg aagagcgttt gctttctgtt
     1921 attgatattg ctagccagcg aagtgattta gtgattttat gtggtggtct tggtccaaca
     1981 gatgatgatc taacgaagca gaccttagct aagtatctgg gaaaagcttt ggtctttgat
     2041 gagcaggcag gtcaaaaatt agatgctttt tttgcacatc gtaagcaggc tgctaggaca
     2101 ccaaataacc aacgtcaggc gcagctgatt gaaggctcta ttgctttgca aaatcaaaca
     2161 ggacttgcag taggtgggtt aataactgta gatagggtaa cctatgttgt cttaccaggg
     2221 cctccaagtg agctaaagcc tatggtaaaa aatgagctgg tgccccttct ttcagctagt
     2281 catgccagtc tatattcaag agtgctgcgt ttttttggca ttggtgaaag tcaactggtg
     2341 actgctctgg aggatttgat taagcatcaa acagatccta ctattgctcc ttatgcaaag
     2401 accggcgagg taacactgcg actatccaca aaggctgaca accaagcatt agctgatgaa
     2461 aggctgaatc gactagaggc gcagctctta tccataagaa ctgtagataa tcaaccctta
     2521 cggcgtttgc tttatggcta tggggaggat aattccttgg cgcgtgagac ctttgagcta
     2581 ttgaagcgaa gtggtaagac gataacagca gctgaaagct taacagcagg actgtttcaa
     2641 gctcagttaa ctgattttgc gggagcttca caggtgttta acggtggctt tatcacctac
     2701 agcattgaag aaaaagcaag aatgcttggc attccattgg gtgagctaca aaggcatggt
     2761 gttgtgagct cttttacagc tgagcaaatg gctgcacagg cacgctgctt gaccaattca
     2821 gatatcggta ttggtctaac aggtgttgct ggtccagagg cactcgaggg acagccagca
     2881 ggaacagttt tcattggcct tgccactaag aataaggtag aatctcttaa agttgttata
     2941 ggaggccgta gccgtttgga cgtgcggtat attgctgccc tatatgcttt taatatggtt
     3001 cgtaaaactt tattaaaatc agagaatttg ctataattag gatagtgtat tttaggaaat
     3061 tagtaactag acagatgtga ggttatgctg tttattgctt gctagtcagc ctaaatagag
     3121 gagaaaatat tggcaaaaaa agttaaaaaa aatgaagaaa tcaccaaaaa atttggtgat
     3181 gaacgtcgta aagcacttga tgatgcgtta aagaacatcg aaaaagattt tggtaagggt
     3241 gcggttatgc gccttggtga gcgtgcagag caaaaggttc aggtgatgag ttcaggcagt
     3301 cttgctttag acattgcgct tggagcaggt ggctatccta aagggcgtat tattgaaatc
     3361 tatggaccag agtcttctgg taaaacaaca gttgccctgc atgcagtagc gcaggctcaa
     3421 aaagaaggtg gtattgcagc cttcattgat gcggagcatg ccttggaccc tgcttatgct
     3481 gcggcgctgg gtgttaatat tgatgagctg cttttgtcac agccggattc tggtgagcaa
     3541 ggacttgaga tagcaggtaa actgattgat tctggtgctg ttgatttggt tgttgtcgac
     3601 tctgttgcag ctctagtgcc tcgtgctgag attgatggtg atattggtga taaccatgtt
     3661 ggcttgcagg ctcgtatgat gagtcaggcg atgcgtaagc tttcagcctc aatcaataaa
     3721 accaagacaa ttgcgatctt tattaaccag ctgcgtgaaa aggtaggggt tatgtttggt
     3781 aatccagaga cgacaccagg tggtcgtgct ttgaaattct atgcctctgt ccgtctggat
     3841 gttcgtggaa caacacaaat aaaaggaact ggagatcaaa aagacagtag tattggtaag
     3901 gaaaccaaga ttaaggttgt taagaataag gttgctccgc catttaaggt ggctgaggtt
     3961 gaaatcatgt atggagaagg catctcacgt acaggtgagc tgattaaaat tgcttcagat
     4021 ttagacatta ttcaaaaggc tggtgcttgg ttctcttata acggtgaaaa aattggtcag
     4081 ggctctgaaa atgccaagag atatttggct gatcacccag agctgtttga tgagattgac
     4141 cataaggtgc gtgttaaatt tggcttgctt gaagatactg aggaaagtgc agctgcagat
     4201 acagttgcag ccaaagcaga tgagttggtt ttagagctag acgatgccat tgaaattgag
     4261 gattagtgct tagtattaga ttttcagata aaggtgctaa aaagggctta acagcgatcg
     4321 tcaagccctt tttagcttgt gtttaatcaa gctctgtatt ggtctgctca ggagctaggc
     4381 tgtacgcttg gataatttgt tagctgagtt tatgttttct ttagggatta actgttaagc
     4441 tataaaagcc ctagaaaaaa gggacttcct acagacaaga tagtggcata gtaagcttgc
     4501 ttgcaactag ctcaatatag gattttggcc ttggttaaag ggatcataaa agaaaactaa
     4561 aaaataggtc caaagaccga tattgattag aaaaaaacta tgctacaata gaggtatcac
     4621 gagatagaaa gtgagaacaa catgataaaa atttacacga tttcaagttg tacgagctgt
     4681 aaaaaggcta aaacctggct gaatgcccat aagctcccat ataaagaaca gaatttagga
     4741 aaagaacctc tttcaagaga agaaatttta gctattttat caaagactga aaacggtgtg
     4801 gagagtattg tctcttctaa aaatcgttat gccaaagcct taaattgtga tattgacgag
     4861 ttaagcgtaa atgaggttat tgatttgatt caggataatc cccgtatttt aaaaagtccg
     4921 attcttatcg atgacaagcg tcttcaggtg ggctacaagg aagacgatat tcgtgccttt
     4981 ttacctcgtt ctattcgtaa tattgaaaat gcagaggcgc gtttacgcgc tgccttataa
     5041 aaagctctgt cagagctttt tttaatatcc taacaaatct gaattcttgt ttattcaata
     5101 aaaataagct ataatagagc gtagcactta aagttagaaa gaaggtgtaa gtatgggatt
     5161 tacagatgaa acagtccgct ttaatttaga cgatggtgat aaaaagcaga ttagcgaaac
     5221 gctgacggca gtttatcatt cactagatga aaaaggctac aatccgatta atcaaattgt
     5281 aggttatgta ctaagcgggg acccagctta tgttcctcgt tacaatgatg ctcgcaacca
     5341 aattcgtaaa tatgagcgcg atgagatcgt agaagagctt gttcgctatt atttgcaagg
     5401 aaatggaata gatattagat gagaataatg ggacttgatg tcggttctaa gaccgtcggt
     5461 gtggcaatta gtgatccact tggttttact gcccaaggac tagagattat taggatcaat
     5521 gaagataaac aggattttgg ctttgataga ttagctgagc ttgttaagca atatcaggtt
     5581 gatcgatttg tcattggctt gccaaagaat atgaataaca ctagtggccc acgtgttgaa
     5641 gcaagtaagg cttatggaga taagattgag gagctctttc acattccggt ttcttatcaa
     5701 gatgagcgct tgacaactgt tgaggcagag cgtatgttga ttgagcaggc agacatcagt
     5761 cgtggtaaac gtaaaaaagt aatcgataag ctggctgcgc agctgatttt acagaattat
     5821 ttagattgta actattaagg agaacagatg acacataatc atgatcacga acacgaagtc
     5881 attacacttg tcgatgagca aggaaatgaa gcattgtttg aaattttatt aaccatcgat
     5941 ggacgtgaag aattcggtaa aaactatgtt ttactagttc ctgctggttc gcaagaggat
     6001 gaatcaggag aggttgagat tcaggcctat tcatttacag aaaatgaaga cggaacagag
     6061 ggtgatttac agccaattcc agaggattca gacgctgagt gggatatgat tgaggaagtc
     6121 tttaatagct tcttagacga agagtaacaa cctgaggcat tagctttaaa ataataaata
     6181 gcctagaatc ttggtgctag cagcatgggt tttaggctat ttttatggtt tatcagacag
     6241 taggagtgat agctatttct atgacctcta aatagcctac tgttaagagt gtttttaggg
     6301 tcttgtagat gttgcaatag cctgtaattt cgttgaagtt acttgctgtt gtctttttta
     6361 gtttaagcct taacaaagct tataggaaat gactcaactt agcacagcat aagccgctta
     6421 ttttgataag taaagaaata gccaatagct acttttagct taaagctgat cattaccagt
     6481 acccttagct tttctgggta ttatttcgaa taatcttaat gggggtgatt ttatcaaaag
     6541 actcagtcaa gaagaaaaaa gctttctaaa gcattatagg ctaaagacac tgcaccgctt
     6601 taaagagctg ctgacttatg ccagcatttg tcataaattg actaaataat agattttgct
     6661 atacttgtaa tatgacatgt caaggagaaa cacattgagt caattacatc aagaagttat
     6721 gctggaaaag gtcaattatt tggtgaaaga ccacccatcg tcacatacga ctaagtatga
     6781 catgaaggtc cctagtttat ataaatttta tatctttttc tttagcatca tagcgagctt
     6841 gcttacggtt gcggttcctt tttttgcaga tactgcaaat agcgttcagt cacaaaattt
     6901 atacatcgga atgatgttga ctaaaggtca gattccatat agtgacttgt ttacaacagg
     6961 aggctttctg ttttttgtgc tcatagcttt gagctatcac ttgggaacaa cggtatggtt
     7021 ggtacttgtt caagcgctgt gcttttattt gacaggtgtt tatttctata aattaatcca
     7081 ttatgtgaca ggtattcaga aggtggcttt aggttttaca gctatctatt acctattgtc
     7141 tattagtctt ggatttggtg gcttatatgc gatccagctt gccctgcctt ttgtcttggt
     7201 atcgctttgg tttttaacca agtattttgc tggcttggta aaggacgagg cctttattct
     7261 ctttggcttt gcagcggcaa tagccatgct aattgagcct aggacgcttc ttttttggct
     7321 gcttgcctgc attgcgatta ttgcttataa tgtgtctcaa aagcatttcg ctcgaggctt
     7381 ttatcagctg ttagcagcta tttttggaat gcttttggtg ttttatacag caggctattt
     7441 tatcctcaat ttacagattt tgagtcctta tttggagcag gcgcttgttt atccgtttag
     7501 ttattttgtg acaggtgatt tatcgctgat tctcggttta acagtccaat taggacttgt
     7561 tcttggcttg ggactgttaa cggggctgct gacgtttatg aagcagccta agctagagtc
     7621 tgatcttgct atgaaatggc tactagtctt tgttgtgttt agctatgctg gtattgcggc
     7681 tatatcgcat gattttcata cttatcacct actgccttta ctgccttatg ctttgatctt
     7741 gctatcaagc tctgttggcc gacaatatga ggcaggactt aggatggtta gtcatcgtcg
     7801 tcgtaagggg aaaaatggtg cgagacgggt tattgctatt tatctaaata agcatttcta
     7861 cgtgccagca atcataatgc taggagcggt ttttggcaca gcttatcagt atgtgaccag
     7921 ctctgctatt aatcaagagc gttctcagat tgctcactat ctaagacaga ggctaacgga
     7981 ggaccaaccc atctatgtat gggacgatac gtcaaaaatt tacctggaaa cgcaggccaa
     8041 gtcagcttca cagtttgcct caccctttgt taatctgaaa aaagagagtc atcaacagat
     8101 gttagaggat gagctactac agaataaggc agtctatatt gtggtcaaca agcaaaaagc
     8161 attaccaaag gcagtcaaga aaatagtgac agctaattat aaaattgaca gaaagattga
     8221 tgttaagggc tttagcctat atcagaaaaa ataaataaaa tcaatatatt gtgttggtat
     8281 aaaaaaactt aacacaatat attgattttt ttgtgtggcg tgatataata gtcgagtaag
     8341 gagataggac atgataacat tagaaaaaga caaagttatt gttcagccag ctattaaggt
     8401 tattaaaaga gatggacgct tggttaattt tgatgcaaca aagatctaca gtgcgctgtt
     8461 aaaagcaagc atgaaggtaa cacgcatgtc accgctcgtt gaagcaaagc tagaagctat
     8521 ttctgaacgc gttattgcag aaattatcga gcgatttcct acaaatatta aaatttatga
     8581 aattcaaaat attgttgagc atgagctatt agccgctaat gaatatgcta ttgctaagga
     8641 atacatcaat tatagaaccc agcgtgactt tgcccgctcg caggcgacag atattaattt
     8701 ttctattgat aagctcattc acaaggatca gacagtagtc aatgagaatg ccaataagga
     8761 tagtgatgtt ttcaataccc agcgcgattt gacagctggg attgttggta agtctatcgg
     8821 tttgaagctg ctgccagcgc atgttgctaa tgcccaccaa aaaggtgata ttcactacca
     8881 tgatttagat tatagtcctt atacgccaat gacaaactgt tgtttgattg attttaaggg
     8941 aatgctggca aatggcttta aaattgggaa cgctgaggtt gaaagtccta agtctattca
     9001 aacagcaaca gctcaaattt cacaaatcat tgctaatgtg gcctccagtc agtacggtgg
     9061 ctgtacagcc gatcgtattg atgagttttt ggcaccatat gctgagctaa atttcaaaaa
     9121 gcatatggct gacgctgaaa aatgggttat tgaggagctg cgggaaagtt acgcctttga
     9181 aaaaacaaaa aaagacattt atgatgccat gcagtctcta gagtatgaga tcaacacgtt
     9241 atttacctca aacggtcaga ccccctttac ctcattggga tttggtctag ggacctcttg
     9301 gtttgagcgt gagattcaaa aggctatttt aacgattaga attaatggct taggcagcga
     9361 gcaccgtacg gcaatcttcc ctaagctcat ctttacggtc aagcgtgggc tcaatttaga
     9421 gccagactca ccaaactatg atattaagac cttagccttg gaatgtgcca caaagcgcat
     9481 gtatccagat atgttatctt atgataagat tattgagctg acaggatcct ttaagtcacc
     9541 aatgggctgt cgctctttcc ttcaaggctg gaaggatgaa caggggcaag atgttacctc
     9601 agggcgtatg aaccttgggg ttgtaaccat gaatttacct cgtattgcta tggaatcaaa
     9661 tggcgatatg gataaattct gggagctgtt taacgaacga ttacacattt gtaaggacgc
     9721 tcttgtttat cgtgtagagc gcgttaagga ggcaacgcca gccaatgctc ctattcttta
     9781 ccaatatgga gcctttggca agcggctagc taagactggc aatgttgatg agctctttaa
     9841 caatcgccgc gcaactgtat cattgggtta cattggctta tatgaggtag caaccgtatt
     9901 ttacggtggg caatgggagc acaaccaaga ggccaaagac tttacaatca ctattgttaa
     9961 ggaaatgaaa aaggcttgcg agacttggtc agatgaatat ggctatcatt tctctgttta
    10021 ctcaacacca tcagaaagct tgacagatcg tttttgccgc ctagatactg acaaatttgg
    10081 cgttgttgct gatattacag ataaagaata ctatactaat tcattccact atgatgttcg
    10141 taaaaatcca acaccttttg agaagctaga ttttgaaaag gcttatccag cagccggtgc
    10201 ttcaggtggc tttatccatt actgtgagta ccctgttttg cagcaaaatc ccaaggcctt
    10261 ggaagctgtt tgggactatg cttatgatcg tgtgggctac ctaggcacaa atacgccaat
    10321 tgataagtgc tatgaatgcc attttgaggg agatttcacc ccaacagagc gaggctttac
    10381 ttgtccaaat tgtggaaaca atgaccctaa gacagtagat gtggttaaaa gaacctgtgg
    10441 ttatttagga aaccctcagg ctcgtccaat ggtcaatggt cgtcataagg aaatctctgc
    10501 tcgtgtcaag cacatgaacg gatcaaccat caagtatccg gggatataag ccttggagaa
    10561 taatctcatt acacctatat cattgtaaag gattgcttca tgcaagcagt cctttagtta
    10621 tcaagacagg tctgtaacaa agaaagggag aaacatggga aaataccagt tagattataa
    10681 gggaatgcag caagtagaga ggtttcatga gaaacattct gttgcaaaaa cagacaaaaa
    10741 gtctcgagta cagcagctta gagcacaatt tttagaaaaa gcaaagcaat caaagaaata
    10801 atggcacact cagtaaaggc ggtgaagaat gctagatatt ggaattgttg ggttaggcgc
    10861 tatttcacaa aaggcctatt taccctatat gcgtcaatta agaggaatca attggcattt
    10921 atctactaga aatgcgttag tccgccagga ggtgggtcag ctttttggtt gcgcaaggct
    10981 ttacagcact gtcaatgagt tacttgaggc taagttagat ggtgtgttta tccatgcagc
    11041 cactaaggct catttagagc tggctagttt gtttttacaa aaaggaattc cagtttacat
    11101 ggataagcct ttgacggagg atttctttag cacgcaggct ctttatcaat tagcagataa
    11161 gcacaatacc tttttgatgg cagactttaa tagacgcttt gcacctggtg tcaagaagtt
    11221 gtcaaccctg tcaaccaaac gtaaagttgt tgttgagaaa aatgatatta atagaccagg
    11281 tgacaaacag tttaagcttt ttgacttctt tatacaccct ttagatacag ctttattttt
    11341 agttgatagg aggcttgttg caggctattt tcattatcag ctgactgata atgatttgct
    11401 aagtcaggtt agtgtaacct taaggacaga acagactatt atttcagcag ctatgaatct
    11461 acagtcaggt agcaggcgtg aggtgatgga ggttcagaca cctaaagaga cctatcacct
    11521 agaaaatcta gagaccttgc gagcttatcg aggggttgat caagagatca agggatttag
    11581 tgcttgggat actaccttat ctaaacgagg ctttgaggct attgtggatt cttttttaca
    11641 ggctgtcaag gatggtgtta accctgtcaa gccagagaca agtctgttga gtcactggat
    11701 ttgtcaccaa atttgtcaat ctcatgaagc tgatggcata ttagatgttt ctcttccctt
    11761 ataaaggagt gataatatga agctacgaag acctaaaaag caagatgaag cgtctgtttt
    11821 agaaatgatg gcagagtttg aagactatca gtctcctcat gatggtggtt tttggaacgc
    11881 tgagcatttt gattatgaaa aatggttgga atctaatgct ctgatggagg ctggcttagc
    11941 tatccctgag aattgggtgc ctgccataca gctcgttgcc tttgctgatc aacaggctat
    12001 tggatttgtc aatgtacgct tgagattaaa cgaacagcta ctggtaaaag gtgggcatat
    12061 tggttattct gttagaccta gccagcgtgg aaagggctat gcaaagctga tgctaaagga
    12121 agccttgcag cttgctcgtc aaaagggcat tcgtgaggtt ttagtgactt gtcattgcag
    12181 caatagtgct agtcggtctg ttattttagc taatggtggt cagctgaagg attgcaataa
    12241 gggtattgaa cgctattgga taaaagcata agaggcaata atgaaggaaa actgttggaa
    12301 ttctcccaaa ccaaaagaat ggacatcaga ggcattaagc caaggacgcg ttattgatta
    12361 taaggcattt aattttgtag atggggaggg agtgcgaaac tcactttatg tttcaggctg
    12421 catgttccat tgtaagggct gctataacgc agcaacctgg tcttttaagg cgggtattcc
    12481 ttatacgaaa gagcttgagg agcaaattat gactgatctt gcaaagccct atgttcaagg
    12541 tttgacactt ttgggcggtg agcccttttt gaatacggga atattgattc ctttgattaa
    12601 gcgtatcaga aaagagctgc cagaaaagga tatttggtct tggacaggct atacctggga
    12661 ggaaatgatg gaagaaaccc aggataagct agagctgtta agcatgattg atattttagt
    12721 tgatggccgc tttgatatca ccaaaaagaa tctgatgctg caatttcgtg gatccagtaa
    12781 tcagcgtatc atcgatgtta aaaagtcact ggctgctgga gaggtggtta tttgggataa
    12841 gctaaatgat ggtgatcagt cctttgagca aatgagccgc gatgatttga tttagtagag
    12901 acttatcaac atcactagac ttgaaagcta ataatgaaag catgatttta ggctcctgtg
    12961 gtcttgctta accaatctaa taaggggttt tccccacatt atcctcatac ttatccacag
    13021 gttgtgaata acctgttggt ttgtggataa aaaagagaat taaggggttc tttaattctc
    13081 taggcctgaa aaagggttct ttttgatgtt ttttcttaaa agaaagagag gcaagtgacc
    13141 tctcttgaaa tagtatactt aggctttaag cctagctttc aatatctctg aatgtctgat
    13201 tttcttagga gtcaggcatt ttttaatggc gatgggaagt acggcttgtg ggtcgctttg
    13261 tgtgctaaga ggctttctga gctgctatat gtcaatgatt ggtgatgtga cagctgaggc
    13321 ttgttcacat tctgaaagca ctgatgtttt tcctagcttt cttttttgat gtagtagtaa
    13381 ttagtttcgg ttgatagctc ctcattatag caaaagccag caaagctcag ctgcttaagt
    13441 gcttccttgg tttggacatt gttttctaga caggctgtta gaaaggctcc tcgagctttt
    13501 tttgaaatgg ttgaatgcgt cttgagctgt cctgatcttt cctccataaa tttgggactt
    13561 atccacagtt tttgatattc ctttgaaaaa acatctctaa actcgttgga taacagagaa
    13621 atgatttgct tgtgatcttt agcaaactga tcgtagatag ggcgccaata atgcttaagg
    13681 ctttgcccat tgatggttac tttagtgtga aaatcatgcc ggtgctctgc gattttctca
    13741 tcagtaggga taatgccata aaaagacgag gtaatgtaga cctgctttga gaggtagtct
    13801 tgctggtctt tagagagatt gtcgcgcttg agatgacggt acatgagccc attaaagagc
    13861 tgataagcag gataagcaga actctgccct tgagctatgg cctttagtct cttggcttcc
    13921 ttgcttgctg cttctatacg gatgctgtag gcccttgcta gctcctctag ggatagttca
    13981 gccatagcct ctaatatggg caggcttttt tggggaagct gatgtggata gcaaggtgga
    14041 actggtttca tttctttagc tgttggaatt aaaaaagtta acataagttt attgtagtaa
    14101 aggcggcaac cttctgtcaa gagtgggata catttggtgg ttatgtcata tgaaactaat
    14161 ttttatattt tttacatttt gattagtttt taaaaatata gtgatttagt gttgcataac
    14221 ctctctaagt atgttaatat atacttaagt ctgtttgata aacagaagct caggtcaagt
    14281 gagtgttcca cttacaataa cgcagttgat gatggggaga ctcagactca gagtcaagga
    14341 aaagaaatat agtcttgtag gattacctac agggcttttt tctattttga attgagagat
    14401 caatataagg tgatgtgctg ttttttatta ccttaaacat ttggatattg gctattgaca
    14461 aaaagtgtaa aggaaactat actatatgtg taaagttaac ttgacatatt ggaggaacca
    14521 tggaaaatcg gatacaagaa ctccgtaagt cacgagggat tagtcaagct gatttggcag
    14581 atatgatgtg tgtcactagg caaaccatta tctccttaga gaaaggacgc tataatgcgt
    14641 cattagagct ggcctataaa ttagcgacat ttttcaatct gactatagaa gacgttttct
    14701 tgtttgaaga gaagggagaa tgagatgata tttagtgatt taagcgtcct gctgactcaa
    14761 aaaagccagc tagcctatgc caaaaggctg aagtatatgg gctttttcgc tctctgttta
    14821 ggcggtttgt ttttgttgct ggcctttgac gtgagactga cgagctttgc tcagggaatg
    14881 ctggtagggc ttggtagtgg tagcttatta ttaggtgttc gtgctttttc agattgcctt
    14941 taatcctcaa aggctgagag cctcttatat taaggcttat gatgagcgtc atcaggtagt
    15001 tatcaagcta gctgctgtat caaccttaat cttattagtg gtgttgatta ttggctgttt
    15061 gtgcttgaat gttttttgga gtttggtttt tggctttaga gtatttttag agatttgtct
    15121 gtatacgatc ttgcttggtt ttttaggcat caagctattg ttagagcata tgatttagga
    15181 ggcttcaatg gaaacaaaac attcagcagt aaaggtcatc atcagtaaat taaaatggtt
    15241 tggcttagct cttcttgtgt ttatgcttga gcaggctcca acatttttga taacaaaaga
    15301 acagccaatg tggcagacac ttcttcttgt ggtcattttt cttttgatta gtggaggtac
    15361 ttattaccta gctgtgaagc ttcacattgt gggagatcaa gctattccta agaatgacta
    15421 tcgggcactt tggattggtt tgggagtggt agctgtcttt gttgtcaaga tgattggtgg
    15481 tattctgttg tttttggagc atggtccggg agccaatacg gtcaatcaag ctgccttaga
    15541 acaggcaggc ttatctccga ttcttatggt tacgctagtt gctattgtgg caccaattgt
    15601 ggaagaaatt gcttttcgag ggctgcttta tgggaagctc tttggtgcag agtcttatct
    15661 gggcttgatt tttagcagta tcatgtttgg cttgattcat gtgccaacag attttggcag
    15721 ttggtttatc tatggcggta tggggctggt gttaggcttt gttttccata aaacaaagaa
    15781 ggtcgaatac acgatattga ttcatttttt gaataatgca ctagctgttc ttatcatgct
    15841 tttgctgcct tatcttcagt agtactgctt gagtaatgaa gggggtaatg aatgaaaaat
    15901 gatcgttgga ttgacaaaaa atatcaacgt tgggagaaag tgtataagag acttggtcat
    15961 tctttactga caatcggtgt gttggtaggg acttatggga tttttttgat tattcaaggg
    16021 aatcatcaaa cgggctttct cctttttatc ctggggccta tactattgat tgcgtcatgt
    16081 ctttgctatt atgtgtttac agagccaacg tctttacgag aatatctgat taatagctat
    16141 gatgagcgta accgagctat tcgtcagaaa gcacaggcct actgcttttg tctatttgct
    16201 tttctctttt tgatgcttgc gatattcttt ccaaatatga cgatcaagga gctttttggg
    16261 tataatcttc cgttgattgt tttcaatctg tatgtcatga ttagagcctg ggttagtaaa
    16321 cacatgtagg tcatgttaac acaaaggagt ctagagcaag ggctttgaat gaaactattt
    16381 ttctaaaaac gcaaaaaatc gcgtgcagta acagattagg ccatgttact gcatgcgatt
    16441 ttgttgtttc aaacgtgagc tcagaatgac atatcctttt tagaaagaat aggtatttag
    16501 ggctgtcttg agctagtctt aggtaatgag cttggagctc attggtgatg gttaggatag
    16561 gtctttagct tttttgatcg ttgtgtcaat ggcagagcag acagaatgtg tcaggcctgt
    16621 tttttcaaga tccatcaagc ctgcaatggt tgtgccgccg ggactgcaga tcttatcaat
    16681 caaatcatgg ggactatctg tgctgactag caggttcttg gcgctagcta ggacagtttg
    16741 actaacgata ctaagggcct tgtctttagg cagtccattt ttgactccgg cctttgccat
    16801 agcttcgatg aaaaggtaaa gataagcagg acttgaccct gctagagcag taaaggtatc
    16861 aaaatccttt tcagctattt caaaggttgt tccaaagctg ttggttagct ctttagcagt
    16921 agctaataaa tcagcagtta ctaagtcatt accagtcaaa gcagtggtgc tttggagaat
    16981 ttgagcattc atatttggca tgatacgtag gagtggcaaa tgagagcttg ttaattgagc
    17041 tagtctgtct aaggaaatac cagcagccat tgacatgata ggctgtttga actgtagagg
    17101 gctaagaaca gtctcaaaga gctgtggctt gatccctaga atgatgaagt caacctgatc
    17161 gatcagctct tggtgagatt gggcgtagct taggtgcaat tggccagcaa tttctttaga
    17221 gcgagctaag gatgagcctg agatgattag ctcgtgtggt gtgtgtgtta ggccttgaat
    17281 gatagcagtt gccattttgc caacaccgat aaatccaatt ttcataataa tgttcctaaa
    17341 aatgaataaa ggctcaatag gctagagtgc tcattgaacc ttagattcgc attttagcct
    17401 tatccttcct agtatttctt gattaaatca actgttgagc ggtcaagctt tttgacaatg
    17461 gcttgcaaaa aggcctgtgc ttctacgaaa tcatctaagg cgtacaagct ctgatgtgag
    17521 tgaatgtagc gagcgcagac accgattgtg gttgaaggga taccgccatt tttaaggtga
    17581 gcagcaccgg cgtctgtacc gcctttacca caataatatt ggaaggcaac cccagcctcc
    17641 tcagcggtgg ttaataggaa gtctcgcatg ttcttaagca tgatgtgtcc gggatcgtaa
    17701 aagcgtagaa gggttccatc accaatatgg ccaggattgc cataaatatc accagcaggt
    17761 gagcaatcaa cagcaaagaa aagctcagga tcaaatgtag tggctgacac atgggcacca
    17821 cgaagcccga cttcttcttg gacatttgct ccagcaataa gggtgttgtg aagtgtctgg
    17881 tcttttaggg cttctagcag ctcagtgacc atgagaacac catagcggtt gtcccaggcc
    17941 tttgagatga tattcttttt attggcagtt aaaatggttt cagactgcgg tacaataata
    18001 tctcctggtg tgatgccaaa gctttcggct tcagttttgt ctgtaaagcc accatcaaaa
    18061 acaatatctg aaaccgctgg cagactagca gcaccatttg ccccgcgcag aaaatgggga
    18121 ggaactgagc ctgaaataac aggaatggct tggccagcgc gagtgtataa ggtaaagcgc
    18181 tgtgagctaa caactagtgg attccagccg ccaatttcaa caacccgcag tgttccatca
    18241 gctttaatct cgctcaccat aaagccaacc tcgtccatgt gagccgcaac aagaatgcga
    18301 ggagcttgat ccgccttgct ttcttttatc ccaaatatgc cgccaagtcc atcaacctcc
    18361 actcggtcaa caagcggcgt gatcttagcg cgtaagtaat cccgaacagt gtgctcgtag
    18421 ccggcgatgc cgtctaattc agtaacttct ttaatttttg aaaataaatc aatcatttgt
    18481 atactccatt tgtcatgtaa gattaaaggt atcacgtctg cctctattct atcatttttt
    18541 agtgaagaat gggaaacagc ttgagcatag gaaaagagtt tgggagatta ggtgtgtctt
    18601 tcttgcttga taagctgctt attatcagtt tgattcagat gagataactg ctggtattga
    18661 tggaatgaaa cagctatgca caacagcctt gacaaggatc gacaggcctg agctgtctta
    18721 tgctatcaat tgcacttagg tagagcagta gcctgatatt gatgtgatta gttgctcttg
    18781 tcaggtggtt tattagtatt tcctaaagtg tcagctagtc ttggctgaga ttgttagctt
    18841 ttgctctagc ctattattcc ctttttgtga taaaatgaaa ggtatgaatg gaaaaaagac
    18901 acgtattgtt tcaggattaa ttggactggg tctgctagcc ggcttgggat tgaggcttaa
    18961 ggaagtctat caagaaagag agcgtcagag agtattggtt gaattgcgcg cctttttctc
    19021 agccttagga gagattgagg tcttgtacat caactccttt agctcaaagc gtgatgatgt
    19081 cactggtggc cttgtcatga cagatggtaa gacctatact taccattacc acaaaggaag
    19141 tattgatttt aaagaggatt tgacatgatt attccaacat ctaaggaaga acttgctagg
    19201 ctaattgaga cagagcctag gctggttttg ttttttacag cagattggtg tccggattgc
    19261 cagtatatct atcctgtaat gcctgagcta gaggctgaaa acccggatat gacctttgtc
    19321 cgccttgatc gcgatgattt tatcgattta gcgcaggatt ggcaaatttt tggcattcca
    19381 agctttcttg ttatggaaaa ggggcaggag aagggccgtt tggtcaatag attacgaaaa
    19441 acaaaggctg agattagtga ctttctagca gcctatcact aagaggagaa aatgagatga
    19501 tttttgcata taataaagag caggtcggtg atgttttgat ggtgatacta gaggataaaa
    19561 aagacatcaa gcgacaggtt gagcgtaagg ggagagtagc gcgtgttttt gcagaagaga
    19621 cagggcaaac ccttgcttgg aatatttttg aggcgtcagc cttaatcgct gttgagggaa
    19681 atgggcaggt tttcttgtct gaggaggagt tagcgatttt aaatgcggag cttgctcaag
    19741 aagggtttac tgaacgatta gaggctagcc cagcccctgt ttttgttgtg gggcaaatca
    19801 ttgagatgat tcctcaccca gatagtgatc atttgaatat ctgtcaggta cagattgctc
    19861 ctgataaggc tgtgcaaatc gttgcaggag cacctaatgc tgctgttggg ttaaaaacaa
    19921 ttgttgcctt gccaggtgct atgatgccaa gtggcagcct tatttttcca ggaaagcttc
    19981 gtgggaagga aagctttggt atgatgtgtt ctccacgcga attggccttg ccaaatgctc
    20041 cacaaaagcg tggtattatt gagcttggtg atgctgcagc ggttggtgaa gcctttgatc
    20101 ctgctaagca ttggcagagc tagcaggact tgatcagcat taaaatggtg tttagtcctt
    20161 cttttgcttg gtgaaaagcc tttggacctt gagccatgca gtgctttttg ctggtctgtg
    20221 actgtcttta gcttcaggat cgaagcatta gagtagctgc ttaacttatt gtcagcgctg
    20281 ttgattgcag tagcgctatg cttgtgacaa gtgaaggcaa agcctatcaa tgcccttggc
    20341 tagggctaaa aattgtcttt agagtcactt ttgaggtgag tagctcgcta atttcggtat
    20401 tgaacggtgc ttaggtaccg tttttttaag ctttgctgag tgtgacatgc tgaaaaaagg
    20461 ccatgtcttt atatggcttt tggtcacaga tggctaattc aatcgtccgc aacacttcca
    20521 gccaatcagg cttagcttta acctcatttg gttgaagtcc gtagcatgtc cgcagtccac
    20581 gatagccttg gagcttcaaa tcggtctttc tgagtaagtc atcaatactg taggtctgac
    20641 ctgctgcaaa ggataaactt tcaaaggctt gtccatttag cacattaagt gccttgtcat
    20701 agtcgtgttc aaaaataaca gagtggagaa cttttccgac ttgattgtgc ttgatgagtg
    20761 atagctgccc tttaggcttc aatagacgtt ccatctgagc taggtagatc gcatgctctt
    20821 ttggggcgat atattctaag acattgtggc atatgatcat atcaaaggct tgatcaggca
    20881 gtttttctag cgcttctaat gaacctttta ttttatgaat gctttcttgc ttttgggcaa
    20941 ataataggtc aggatttggc tcaattgcag ttacttcatt ctggacggct aatgcctctg
    21001 ctgtgatgca aaagcctgct ccgaaatcta aaatagtctt gcctgctatg gggcctaatt
    21061 gggcaaagat caaatcatac atgagctttc cccagggcct tgtgagcatg tcttgatagg
    21121 ctttaagatt aatagtcatt atctagtttt cctttcttta gctgctgtga gctattggca
    21181 ggatttctaa acttcacagc ttgtccttat tttaccatgt tttacgaata ataagataag
    21241 gaggtatgac atgtacaata aagtaatctt gataggccgt ttagtggcca agccagaatt
    21301 aaacaagaca ttaacggata agcaggtcgt tcgatttacc ttagcagtta atcgtcggtt
    21361 taagacgacg actggtgagc gtgaggtgga ttttatcaat gctgttgctt ggggaggttt
    21421 ggctgaaacc ttggcttcct atgctagcaa ggggagtctg ctgtcacttg atggcgagct
    21481 tcgcacacga aaatatgaca aggcgggtca gactcatttt gtgacagagg ttttgtgtca
    21541 ttcttttcaa ttgctggaaa gtcgagcgca acgagctata cgtgaaaaca acgctgctaa
    21601 tgatttgatt gatttggctt tagaggagga aaagcttccc ttttaaagac agctgctagc
    21661 ttactgtcgc taagggagtc agacactagc attgtgtatg ctagagatct caacataatc
    21721 taaaaaatgg caacgattct aaaaaaaatc ttgacacgtc ttagaaaaag gtttacaatg
    21781 tatgacaatt aaaatgaaag aaaacaggag gtgctggtat ggtagcagtt agcacagctc
    21841 agacgatgac taagcgttat tactttagct tctttagata gtgtttgtag acatgagcgc
    21901 atggatacaa acacactgaa cgttatgttt gtatctatgg ggctaagggc tatttgagtt
    21961 gtttgtccac atagatgata tctcttctaa gtggacacca tacagcatgt attttgttat
    22021 ctcatgatac ctgtatagga ccatttagat tatctagatg gtcttatttt tatgcaagaa
    22081 agaggaaatg acatgagatt taaacagtta tccttaacag cctttatagg gcttttggca
    22141 atgctgctaa cggcttgtcg acaagaaacc aaccaaacac atcaagctgc tagagttggg
    22201 attattcaat atgctgagca ctcagcccta gatgctgcgc gtgagggttt tattgaggcg
    22261 cttgagcagg gcggctttag agaggggaag aacctgacca ttacaaccaa aaatgcacag
    22321 ggtgatcagg ctaacctgca aacaatggtg gagcagctgg cgggtaagaa cgatttgcag
    22381 cttgcgatcg caacgccggc agcgcaggcg cttttaaata tggactcaga gacaccagct
    22441 gtatttacag cggtaacaga tcctgtctca gcaggtctgg ttgatacatt agctaagcct
    22501 ggtgggaata tgacaggctc tacagatgcg actgatgttg agaatcagat tgatttgttg
    22561 accaaggcgc tgcctcaagc taggacagtt gggattttct acaattcaag cgaggtgaat
    22621 tcggagatac aggctaagaa ggccaagagg gagcttgaga aaaaaggctt aaaggtcctt
    22681 atgaaaaccg taaccactac taatgatgtg cagcaggtta tgacaagctt ggctagtcag
    22741 gttgacgctg tttacctgcc aacagataat acggttgcct caacagctac tactattggg
    22801 gatattttaa aggaggccaa aattccttca atgggaagcg atgctgctta cctgagtgct
    22861 gttttgttca cctcaggtgt tgattaccat gctattggca tgcaggctgg tcagcaggcg
    22921 gtagatattt taaagggtaa aaaaccagca agcattcagg ttgctaagcc tcaaaaggca
    22981 agcattgctg ttaatgatga tatggcaaga cttctgggca ttgaccccga ggtgatcaag
    23041 gctcttgcaa gtaacggagc caactagcgt tttaggagga aggtatgaaa aaaggaagct
    23101 atttaatact gttagtgctt gcaggcttcg ttttggtggc ttgtcgttcg acagctagtc
    23161 ctcgtaaggt taaccaatct catgttaaca tcggtatttt acaatacatg gaacatgatt
    23221 cgctgacggc agctcgtcga ggctttgaag cgcaattaaa ggcagcgggc tatactaagg
    23281 gagacaagct gagccttcat tatcaaaatg cacagggcga ccaagctaat ttacagacga
    23341 tttcagagca gctagtgaag caaaatgatt tgatcttggc gattgcgaca ccggcagcgc
    23401 aagccttagc gaccgtctca tcagatagac caattgtttt tacagcagta acagatccta
    23461 tctcagcagg cttagtggat aggatcaaaa agcctggtgg cttgataaca ggaacaagtg
    23521 accaggcgcc gattgcaaag caaattgact tgttagccca agccttgcca gaggccaaaa
    23581 ctattggcat tttatacaca gctagtgaac gtaatgctga ggtgcaggta aaggaagctg
    23641 aaacgctact gaccaaggtt ggttataggg ttattaaaaa gggaattgcc acttcaaatg
    23701 atgtgcaaga tactgctgca agcttgatga gagcagtaga cgcgcttttt gtaccgacag
    23761 ataataccgt tgcttcaacc atgacaatgc tgggtgagct gtcattggct aataaggttc
    23821 caattattgg tggctcaacg gatatggttg atgcaggtgg gctcttgacc tatggtatcg
    23881 actacgagag ccttggtaga caggctggag aaatggccat taagatttta agaggacagg
    23941 atccagcaag cctagcagtg gagtacccaa aaacagtcaa gctacatatc aatcaagcaa
    24001 tggcagacaa gctagcgatt gatacttcca cattatcagt tgactaaatt gctaggttaa
    24061 aggctaaatg actgatctct agccagctgg ctaaatgaca aagtcttaac cagttagctt
    24121 agcttactat taacgattca tatgacaaaa aaggagaaat catgtcactc attttatcga
    24181 gcttatcaca gggcttattg tggtctatta tggcaattgg tgtttacctg acatttcgta
    24241 ttttagatat tgccgattta actgcagaag gttcctatcc gcttggggca gctatttgtg
    24301 caacgggtat tgtatcaggt gtttctccct tgctggctac gtttttagct tttattggag
    24361 gcttgctggc aggccttgtc tcaggattag ttcacaccaa attaaaaata ccagccttac
    24421 taacaggaat tatcactctg acaggcttgt attctgtgaa tctaaaggtg ctaggaagag
    24481 ccaatgtggc tttattacgt caaagaactt tagttaccca gctctatgat ctaggcttta
    24541 ccaagcttgc agcggtgcta attatgggct ttgtctttgt gaccattgtg atttttttat
    24601 tagccctgct gatgaaaact cagcttggcc tagctctgcg atcgaccgga gacaataatc
    24661 caatgagtga agccaatggt atcaaaacag atcagatgaa aatcatgggg tatatgctat
    24721 ctaacggttt gattgcccta tgtggtgcct tgctttgtca gaataatggc tatgcagatt
    24781 taaatgctgg tgttgggaca attgttattg ggctggcttc gattatcatt gctgaggtga
    24841 tgattaggca gctaagcatt ggctggcgct tagcttccat tgttttaggc tctattgttt
    24901 atcgcttaat tattctagct atcctagcca ttcccggtat ggatgcagat ttggttaagc
    24961 ttttttcagc catgctattg gcagctgttc tttttgtgcc agaattacag caaaggcttc
    25021 gccttcgaaa aacaagttta ggataggaga aatcatgtca gcaatattat caattaaggc
    25081 tattcacaaa acatttgaag caggtacgat taacgaaaat catgtcttga gaggcttatc
    25141 tttggacatt gaggaggggg attttatctc ggttatcggt gggaatggcg ctggaaaatc
    25201 cacattaatg aatactctag caggcactct ggcttttgat cagggcgata ttcttttaga
    25261 gggaaaatca atcaagcatt tatcagccgc taagcgtgcc aaggacatca gtcgagtgtt
    25321 tcaagaccct aagatgggaa ccgcttcacg cttgaccatt gaggaaaata tggctattgc
    25381 ttaccgccga gggaaatcaa gggggctagg ctggggcgtt aaagaaagag agcgccagat
    25441 ctatcgtcag gccttgcagg aattaggcct aaatctggaa aaccgtctta aggccgagac
    25501 acagttttta tcaggagggc aaagacaagc cttgaccctg ttaatggctt ccttagcaaa
    25561 gcctaaggtc ttgttgctag atgagcatac cgcagctctt gatcctaaga ccagtacaat
    25621 ggtaatggct ttgacaaagc agcttgttga gacacatggc ttgacaaccc tgatgattac
    25681 ccataatttg gaaaatgcta ttgcttatgg taatcgtctg gtcatgctcc atcaaggtaa
    25741 tattgtggtg gatattaaga gagaagagaa ggccaagctg acggttgacc acttgatggc
    25801 actctttcac caaaatagtg gtcatacgct ccttgatgat gcacttgttt tgggataggc
    25861 taggtgaggg ttagctctgt tttcaaatag cagccataat gaaaaggctt aaagccaacg
    25921 cttctagaaa cgctagctca agccttgtta taatacttag gagatttttc taagagtgat
    25981 aaagccatga tgacgtctat tgtagtcaaa ggatttgttt cggatgcgat aagcctcatt
    26041 ttccacaatt tcaattgcct tattcagctg ctgaatggta atcgcctcat caatctcatg
    26101 aaaagcagtg ctataataat cctcactaac acgttgattg cggtctttat aggtattttt
    26161 atgctctgtt aaaatggcct tagcctcagc acgttttgca atggtatcta taataccttg
    26221 accatatgct ctagcctctt gaaggattga cagcatattg tctagagaat atgcgtttgc
    26281 taagcggctg acaaagctat cagcgacctc aggacttaaa ttaataccat ctaagtgata
    26341 aatcatctct gggtgtagct ttaggtaata ctgcaattcg cggaacaaaa gcgctggaat
    26401 tttcgacgaa tccctatatg gattgagctg aatctcctga ctatgtagcc tattgataaa
    26461 atcgtccttg aactgcttaa tagcatcgta gtctgatttt tctagctctg ctttaatatt
    26521 ggctagaatc tgggcgtctg aataacgacg atagcttgat agtgaagcag caggcctact
    26581 agtattggaa tttcgagaag cttctgctct tctagtctct ttgcttggtg tttgctgctt
    26641 atttgactga gtctcctgct cggttagtcg tagctcaggg tgtaaacgac taatattgtt
    26701 aagaaattgg ttaacctcat attctgatga aaactttagc ctaggtctgg ccttgacctt
    26761 ctcaatagcc ttgtcaataa tccttttccc gtaccttttg agattactgt cagactggat
    26821 caaataaaga ttaacatgta agtgatcttg actatccgcc ttagataagc tgttaccaag
    26881 gccaaggctt cctaagagcg tagctagtaa cagcaggtgt tttactagac tacgctgaac
    26941 aatattgtga cgactaagca taagttattt tcccattcta ttgtaatata ccagaaaatg
    27001 ttatcaaaat aaagataaga tgtcaatgtc attaatggtg gttaatcttt aattaatggt
    27061 cgttaatcta gtatatcaga gagctagctt aggctggcag tggtcattct gtgcgtcttg
    27121 gtacgaaatg cccaagcaga tgcagctcac tagaatgatc aatagcctca acacaaagcc
    27181 ccttacagct tgacacaagc tgtaaggggc tttgttgtat taacagataa ctcaaatcct
    27241 tgctttttat aataaatcta aggtttttag cttgtcatca atcatgtgca gaacggttgc
    27301 caaatcctct gggttttgca cgaaatcaag cttgtttcca tcaatcttca tcttaggtga
    27361 aacgtcatat tgctcatacc agcttgggta ttcaccatgt acctgatggt aataggcttc
    27421 taagtcagga ttgtcgtcaa cctgctcaaa acgtctgccg cgcttttcaa tgcgctctag
    27481 catcttctca aaggagacat caatataaat cagcagatca ggccgttttt aaggcattcc
    27541 ttcaagctcc tctagcatat tggctaagag ctcttggtaa atttcaagct ctgtcttggt
    27601 aacatttcca tttttatagt taagtgtcaa gaagagctca tcttcaaaga ttgagcggtc
    27661 aagaatatta ttgtctgcct ggtaggcttc tttaatagat ttgaagcgct tgttcaaaaa
    27721 gaaaatttgt agtaaaaagg catatttttt agggtcttgg taatacagat caagaacagg
    27781 attgttatca acagcctcgt aaaatacctc tgttcctaaa tgctcaccca gtgcagcagc
    27841 aagggaactc ttgcctgcgc cgattgttcc agctaataca atcaacatgt ttctccttct
    27901 atgtagtctt agtgtatttg tgcaaaaatc gtttcaacct cagctaaggt tttagcgcgt
    27961 gaaacggcac tgcgaatttt ggcagcgcct gctgtccctc gcaggtaatg aggggctaac
    28021 ccacgaaatt cacgaacagc aatagcttct cccttgagcc tgatgaggcg cttgagatgg
    28081 tctttagcaa tatctagctt tttagcaaag ggcagctctg gcaaaacctc tcctgtctca
    28141 aagaagtgat taatttgggt gaagagataa gggttgttca tagctgcacg gccaatcatg
    28201 accgcatcta caccaatctc ctcaatcatg aacctagcgt cctgaacagt tctgacatct
    28261 ccatttccaa taaatggaat cctggtaata gctcttgaga cgcgtgcaag ggtttcatgg
    28321 tcacaggtgc cagtatacat ctgctcacga gtacggccat gcatggcaag agctgacaca
    28381 ccagcagctt cagcagccaa ggcattctca acagctagtg agctgtctgc ccagccggta
    28441 cgcattttga cagtcagtgg aatgtctaaa acagaggtta cctcctgaat gatatggtaa
    28501 atcttatcag gatcgcgaag ccacttggca cctgcttcat ttttaaccac cttgttaaca
    28561 ggacagccca tattgatgtc aacaatgtca gccttggtat ggctctggat aaaatcagcc
    28621 gcacgcttta gtccttcagc gtcaccgcca aatagttgga ttgacatggg gtgctcattg
    28681 tcatcaatat gaagcatatg cagggttttt tcgttattat agagaagtcc cttttcagaa
    28741 atcatttcca tgacaacaag gcctgcacca aattccttgg caatcgtgcg aaaggccgaa
    28801 ttggtcacac cagccatagg tgcaagcact gtacggtgag ggatttccac atgaccaatc
    28861 ctaaagggtg agttaagcct tgtcattgat cagcacctcc aaatcagttt ggtcaaattg
    28921 gtacttggtg ccacaaaatt ggcaaacaat ttcagccccc ttatcctcgt ttagcattgt
    28981 caacaggtca gctttaggga ggctcattag ggctgacgca aagcgctctc ttgagcagtc
    29041 acactgaaag ctcagctgct cttcagctaa tcgcttgtaa ggctcttcac cataaatagc
    29101 tgctaacaga gcgtctatat gattttccga cgctagaagg gttgaaatcg caggcatttc
    29161 ctgaatgcgc ttctcatagt ggctaatctc ttcgacagaa gctccaggca gcacctgcag
    29221 cataaagccg ccagcaacct tgaccttgtc ctcttgatct agaagcacat taaggccgac
    29281 agcagatggt gtctgctcag actctgtcaa gtagtaggcc agatcctcac caatctcacc
    29341 ggtaatcaag ggtgttgtag aggtgtaggg attgcctgtt ccatagtccg taattgtcac
    29401 aaagtgtccc tgtcccataa aaggaccaac cagtacttct ccagttgctg tttttttgat
    29461 atcaacaccg ggattttgaa tatagccctt gacatgccct tttgtgtcag caacagaaat
    29521 aatatgccca aaggaggaat cgccaataac cttgacagta accttactat ctcctttttg
    29581 gttggcagct agaatctgat tggcaatcaa ggtacgacca agtgcaaccg ttgaagatga
    29641 taaggtatga tgcctttcct gagcatatcg aacagtttcg gtgcaatcca aaacataggc
    29701 cctgaaggca ccggaggcag aaattgtttt aattagttta tccataattt ctattatagc
    29761 ataatgaaca aggcttgtgc tggttgcttt agaggaaagc tgcttgaaaa tagagaaaca
    29821 ctatttggtt aataatagca gctctataaa gccacttaaa aacagagcag tgctaacaaa
    29881 tggtagtatt cttgtcctta gcacgcagta agctaatcac ctaagtcagt acaatcaaac
    29941 aagcatcaaa aaacagctcc gataggttga ttaaaggaag aaatgataaa agagttattt
    30001 cgtaatgctt tgctgataat gagcaaggta atcatgtggt gtcgtatcag tgtacttttt
    30061 gaaggttttc aaaaaatggg tggtatcgta gaaataaagg agcttagcca cttctccagc
    30121 tggtactcct cttcgtaaaa gtagcttggc ttcttgtact ttttccttca aaatataggt
    30181 ctgcaacgaa atagaagaat acattttaaa aacagctcgt aaatgtgact ctgagatata
    30241 aagatgctta gcaatatctg atacctttaa ttttgaataa aggtgcttat cgacgtaata
    30301 taaaatacta ttataaattt gctgcttatc agaaacactt ttgttagtca atgattctga
    30361 gaggctaata atagcagctg ctcttatttg aagcacctta aggagatctg tagctttttc
    30421 agttaggttc ataaaatgct taatgcgctc gtagtttttg gcaacatcag tattttcagt
    30481 aaagcttagt tcaagcagct taataaaata aataatagaa agattttttt cagctcttaa
    30541 tgcgggaata gaagaggaga cgacatctga tgaagggata caattgattt cgtgctttaa
    30601 tagctctgta ttacccagct tgactaaatc aataatatga ttcaaataat ttaagacagc
    30661 tggcacatga aatgacgggg tattttccaa ttcgagatta gctataatat gaggatcctc
    30721 ccagattagc tgggcttcct ccagtaaatc attaatgctt tgctggcagc tcatttcaaa
    30781 gttggtgtca aaaaaggcat caacagctat caaaaggctt cgaatatgag aagcaggaaa
    30841 atgaggaatg gtagagatat agccaactag ctcttttttt gacttatcag gatagcgctt
    30901 caagaagcta tcggctaatt cctccttata gctatcctga aagaaagagg tgtaaaaagg
    30961 cccaatgaaa ataaacttgt caccaatagg aaacattaga gaggattcct caagcgttcc
    31021 ctcataacaa gtgagctcag tattactagg aatatctaat gttttaatta attcatagta
    31081 ggggaatcga cgctcctcgt catcataagc ctgaaggagc tcaagatttt gagaaagcac
    31141 taaaacaggt aattgtgata ggttatg
//
LOCUS       DARYXW010000013        30519 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.013, whole genome shotgun sequence.
ACCESSION   DARYXW010000013 DARYXW010000000
VERSION     DARYXW010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30519
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.013"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(<1..1435)
                     /locus_tag="TV191_000497"
     CDS             complement(<1..1435)
                     /locus_tag="TV191_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEL1507039.1"
                     /translation="MKFTIVRNYDKLSRTILRLESDKMTIFRKKRQAINKTEMNRHLK
                     MLDLIFLGLGSMVGTGIFTITGIGAANYAGPALTISIILSAIAISILALFYAEFASRI
                     PANGGAYSYVYATLGEFPAWIVGWYIIMEFLTAISSVAVGWGSYLKGLLANYGLQLPN
                     ALNGTFDPQKGTYVDLLPVLVMLLVTAIVLMNSKAALRFNSFLVLLKFSALALFVIVG
                     LFFIDVANWSHFAPYGFGQIYGGKSGIFAGASVMFFAFLGFESISMTVDEVKEPQKTI
                     PRGIVLSLTIVTILYVIVTMVLTGIVHYTKLDVPDAVAFALRSIGLYWAADYVSIVAI
                     LTLITVCISMTYALARTVYSISRDGLLPRALCQITEKTRIPRNATLVVGALSMICAGI
                     FPLASLAEFVNICTLAYLVIMSFAIIKLRKNAGEPQRGEFKTPFVPLLPILAIIICVT
                     FMSQYMVFTWIAFGISTILGIVVYACYG"
     gene            complement(1525..3495)
                     /gene="ftsH"
                     /locus_tag="TV191_000498"
     CDS             complement(1525..3495)
                     /gene="ftsH"
                     /locus_tag="TV191_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEL1507040.1"
                     /translation="MKNNKNNGFVKNSFIYILMIVIVVAGFQYYLRGTSTQSQQISYS
                     KLIKHLKAGDIKSLSYQPSGSIVEVKGKYEKPQKVSIDTGLSFLGNSAATEVTEFTAL
                     ILPSDSVLKEMTSVADKNGTDITVKQESSSGAWITFLMSFLPIVIFAAFMMMIMNQGG
                     GARGAMSFGKNKARSQAKGDVKVRFTDVAGAEEEKQELVEVVDFLKNPKKYKALGARI
                     PAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAKK
                     AERAIIFIDEIDAVGRRRGAGMGGGNDEREQTLNQLLIEMDGFEGNESIIVIAATNRS
                     DVLDPALLRPGRFDRKVLVGRPDVKGREAILRVHAKNKPLAEDVNLKVVAQQTPGFVG
                     ADLENVLNEAALVAARRNKTKIDASDIDEAEDRVIAGPSKKDRSISQREREMVAYHEA
                     GHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKDDLKEQLAGLMGGRV
                     AEEIIFNAQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMMPGQLSPEKS
                     YSAQTAQMIDDEVRDLLNEARNKAADIINDHRETHKLIAEALLKYETLDAAQIKSIYE
                     TGKMPNDPENDEAEVHALSYDEIKDKMTEAKE"
     gene            complement(3517..4059)
                     /gene="hpt"
                     /locus_tag="TV191_000499"
     CDS             complement(3517..4059)
                     /gene="hpt"
                     /locus_tag="TV191_000499"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012961310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEL1507041.1"
                     /translation="MLEQDIQKILYSENDIIQRTKELGEQLTKDYHGKNPLMVGVLKG
                     SVPFMAELMKHIDTHVEIDFMVVSSYNGGTTSSGEVKILKDVDTNIEGRDVIFVEDII
                     DTGRTLKYLRDMFKYRKANSVKIITLFDKPEGRVVDIEADYVCYNVPNEFIVGFGLDY
                     AENYRNLPYVGVLKEEVYSK"
     gene            complement(4064..5347)
                     /gene="tilS"
                     /locus_tag="TV191_000500"
     CDS             complement(4064..5347)
                     /gene="tilS"
                     /locus_tag="TV191_000500"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEL1507042.1"
                     /translation="MTYQHIYNIIKKKAYFDAHQAVLIAVSGGVDSMNLLHFLHAFQA
                     KLQIRIGIAHVNHKQRPESDDEEAYLRSWAKKHAIPIYVAYFQGAFSENAARHLRYQF
                     FEEIMQQEHYSALVTAHHADDQAETILMRLIRGSRLRHLAGIREVQPFANGQLIRPFL
                     TVSKAELPNPFHFEDHSNDSMAYFRNRVRHHYLPDFKRENPQATQSLIDLSAESRLLL
                     QAFDDLTKGLEFHRLNCFLAQSAAVQFFLLQHYLETFPQLAIKKSQFDDLLHIIRRQK
                     QGIYPIKNTYCLLIEKESFAIKKIIPKTDLNREFKMVSYGDSLNYRGYRFVFSGSLTD
                     KGHDIAIPLYSLSPVTLRHRQAGDRLFLGEFSKKLRRLFIDGKFTSEQRQNAIVGEQA
                     GVIIFVLVGDETYLRKASKHDIMLAKLYIDKLEKR"
     gene            complement(5344..6630)
                     /locus_tag="TV191_000501"
     CDS             complement(5344..6630)
                     /locus_tag="TV191_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HEL1507043.1"
                     /translation="MKKLLAAMLMTFFVTPLTVISTEKIPVFSEATRYHLSQDIVSST
                     LYYSRIPTNPNVFEETVAYRDPELSVPKTMIAPDNRIVIKDVLLNKAAIPVFRLADDT
                     YLEASRQIVYEDIMFEQTAVDLDFWTQKKMTIYAEPYVLGVKTIASDSEPGRKVHASK
                     MAQTEHGTYYFIDHKGWVNQKELSPTDNRMLKVQEMLLQKYNKENYSIFVKQLNTQAS
                     AGINADKQMYAASISKLATLYSVQKKLKSGSLSEGKSLKYIDEVNHFYGDYDPTGSGK
                     ISKTADKKDYNVMELLKAVAQQSDNVATNILGYYLCNQYNQAFQSEIRALAGVDWDME
                     KRLLSSHAAANLMEAIYYQKGQIISYLSQTAFDDQRISKNISVPVAHKIGDAYDYKHD
                     VAIVYGDNPFILSVFTDKASYDDITAIADDVYSILK"
     gene            complement(6772..7143)
                     /locus_tag="TV191_000502"
     CDS             complement(6772..7143)
                     /locus_tag="TV191_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEL1507044.1"
                     /translation="MKKPSIVQLNNHYINEENIKKRFEEEEIQKRNRFMGWILVSMMF
                     LFILPTYNLVKGYVSLKKQGQQIITLEKEYRELEKKTKSEKQLAEQLKNDDFVKKYAR
                     AKYYLSREGEVIYPTPGLLPK"
     gene            complement(7130..7402)
                     /locus_tag="TV191_000503"
     CDS             complement(7130..7402)
                     /locus_tag="TV191_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEL1507045.1"
                     /translation="MRLDKYLKVSRLIKRRSVAKEVADKGRIKVNGILAKSSTDLKLN
                     DQVEIRFGNKLLTVRVLDMKDSTKKEDAAKMYDIISETRISSDEEA"
     gene            complement(7433..8944)
                     /locus_tag="TV191_000504"
     CDS             complement(7433..8944)
                     /locus_tag="TV191_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HEL1507046.1"
                     /translation="MRLNLEKLPHKTKQSSLLIVISGFMSKLLAASYRIPYQNLVGDR
                     GFYAYQQIYPLLGIISALGLTALPNVIASMAQKKKQLQLAALFKLQCYTSFLLSGILV
                     LSHKALASWMGAQQLAPSIVITAMVLLIVPFISFYRGLAQADMNMAPTALSQVLEQII
                     RVAIIIVAALCYRVLGWTVYLTANVAAFGNLVASLVILAYLKRHSAYSLKSFLSGDTV
                     AIRDLTSLGLPTLVFLLFSIYLLVFQLIDSLLVKNILVSSGLSEITAEMTKGVYDRGQ
                     PLLQFGLIFSTALFTAYLPNLTVLFHIKRESYREQSQCFFEFIFYFSLTLTVGFISIL
                     HLMNRALFEDNKGWLALVVYLMIIAVSSMIQFFHQKCFIEDHIKQSLLILLFGFLLKL
                     GLTPILTYYYAIVGSSLSTLIPLLVVLLLYAVLADIDFKAIVNAKYGLALVIMLMCVL
                     TSQYCLPLSGRLGALISLLVSSAVGLSSFLIACKKLGVFKEKLWSFLPFVKEK"
     gene            complement(8913..12407)
                     /gene="mfd"
                     /locus_tag="TV191_000505"
     CDS             complement(8913..12407)
                     /gene="mfd"
                     /locus_tag="TV191_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEL1507047.1"
                     /translation="MDILELFNQNKSIQTWQCDVTSLKRQLVMGLSGSSKAAAIASAY
                     LSFQGKLVVVTSTQNDMEKLAGDLSALLDEGSIFQFFADDTAAAEFIFSSMDKTISRI
                     EALAFLSNPEARGILVISLAGLRILLPSPKTFQQGQIDLAVGVDTDLDNVVKKLVKIG
                     YQRVAQVLSPGEFSRRGDILDVYEVTQDLPVRIEFFGDEIDGIRSFDIESQKSLQKKD
                     STSIKPASDMIFEPEDFDRASHNLEKQLQLAKAEHKGYLEELLTVTKEGLKHKDIRKF
                     QSLFYDNEWTILDYLPKGTPVFFDDFQKLVDRNAKFDLELAHLLTDDLQQGKSLPFLH
                     YFADNYRELRHYKPATFFSNFHKGLGNIKFDKVYSLTQYAMQEFFNQFPLLIDEIKRY
                     QKSGATVLLQVESHQAYERLAKSLEAYQCQLPLVSADAIVLHQAQIIIGHLAGGFYFA
                     DEKLVLITEHEIYHKRLKRRARRTNMSNAERLKDYNELSKGDYVVHSVHGIGRFLGIE
                     TINIQGVHRDYVTIQYQQSDRISLPVDQLESLSKYVSADGKEPKINKLNDGRFQKAKQ
                     RVKKQVEDIADDLLKLYAERSQQKGFQFSPDDELQRAFEEDFAFVETDDQVRSIKEVK
                     KDMESVRPMDRLLVGDVGFGKTEVAMRAAFKAIGDHKQVAILVPTTVLAQQHYENFRE
                     RFENYPVEIAVLSRFRSKKEQSESLERLKKGQVDIIIGTHRLLSKDVIFSDLGLIVID
                     EEQRFGVKHKETLKELKTKVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPVQ
                     TYVLENNPGLIREAIIREMDRGGQVFYVYNKVDTVDKKVAELQELVPEASIGFVHGQM
                     SDIQLENTLMDFINGDYDVLVATTIIETGVDISNVNTLFIENADHMGLSTLYQLRGRV
                     GRSNRIAYAYLMYKPDKVLTEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNILGA
                     SQSGFIDSVGFDMYSQLLEQAIASKQGRALTRQKGNAEINLHIDAYLPSDYIKDERQK
                     IDIYKRIREIDSRAAYSDLQDEIMDRFGDYPDQVAYLLEIGLLKYYLDTAFAELVEKR
                     DHQVMVRFEVASLQYYLTQDYFEALSKTSLKARISEHQGKIEIIFDVRRQKDHVILEE
                     LILFGETLGEIKSRKASS"
     gene            complement(12410..12979)
                     /locus_tag="TV191_000506"
     CDS             complement(12410..12979)
                     /locus_tag="TV191_000506"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEL1507048.1"
                     /translation="MVKMIVGLGNPGSKHQQTKHNVGFMAVDRLVKDLDVSFTEDKTF
                     KALIGSTFINQEKIYFVKPTTFMNNSGLAVRALLTYYNISTKDLMVIYDDLDMAVGKI
                     RLRQKGSAGGHNGIKSIIAHIGTQEFDRVKIGIGRPSHGMSVINHVLGKFDTDDMITI
                     NIALDKVDKAINYYLQEKSIEKTMQQFNG"
     gene            complement(13138..14253)
                     /gene="ychF"
                     /locus_tag="TV191_000507"
     CDS             complement(13138..14253)
                     /gene="ychF"
                     /locus_tag="TV191_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEL1507049.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTELITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESINKRYARVEKMARTQKD
                     KDSVAEFAVLEKIKPVLEEGKSARTISFTDDEQKIVRQLFLLTTKPVLYVANVDEDKV
                     AIPDAIDYVKQIRDFAATENAEVVVISARAEEEISELDDEDRSEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGIKAPQAAGIIHSDFERGFIRAVTMSYDD
                     LIKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(14337..14702)
                     /locus_tag="TV191_000508"
     CDS             complement(14337..14702)
                     /locus_tag="TV191_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1507050.1"
                     /translation="MMTKFAEQLKKYRLEKQLSQDALAEKLFISRQAISKWENGDATP
                     DLENLVTLAAVLEVTLDELVTGKEPAIKVIKKTEKPMNVWEFLTEESKRPMRKGDLLM
                     LLLVVIVLLGVYFIVIHFS"
     gene            complement(14823..15020)
                     /locus_tag="TV191_000509"
     CDS             complement(14823..15020)
                     /locus_tag="TV191_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEL1507051.1"
                     /translation="MYQVGSLIEMKKPHACVIKETGKKANQWKITRVGADIKLQCTNC
                     NHVIMLSRHDFERKMKKVLQP"
     gene            complement(15098..16234)
                     /gene="dnaN"
                     /locus_tag="TV191_000510"
     CDS             complement(15098..16234)
                     /gene="dnaN"
                     /locus_tag="TV191_000510"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEL1507052.1"
                     /translation="MIQFSINRALFIQALTATKRAISSKNAIPILSTIKIEVNPSDIT
                     LTGSNGQISIENTIPVSNENAGLLITSTGAVLLEASFFINIISSLPDVSLEFKEIEQH
                     QVVLTSGKSEITLKGKDVSQYPRLQEVSTENPLILNTRLLKSIIAETAFAASMQESRP
                     ILTGVHITLSQHKNFKAVATDSHRMSQRLITLEKTSADFDVVIPSKSLREFSAVFTDD
                     IETVEVFFSASQMLFRSDYISFYTRLLEGNYPDTDRLLMKQFETEAVFNTQSLRHAME
                     RAFLISNATQNGTVKLEIEANRISAHVNSPEVGKVNEDLDVVSQAGNDLTISFNPTYL
                     IEALKAIKSETVKIHFLSPVRPFTLTPGDDEESFIQLITPVRTN"
     gene            complement(16391..17743)
                     /gene="dnaA"
                     /locus_tag="TV191_000511"
     CDS             complement(16391..17743)
                     /gene="dnaA"
                     /locus_tag="TV191_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEL1507053.1"
                     /translation="MTENEQIFWNRVLELAQSQLKQATYEFFVHDARLIKVDNHVATI
                     FLDQMKELFWEKNLKDVILTAGFEVYNAQIAVDYVYEDDLMIEQQHQGQQGYTEQAFQ
                     QLPAVQSDLNPKYSFDNFIQGDENRWAVAASIAVANTPGTTYNPLFIWGGPGLGKTHL
                     LNAIGNSVLLENPNARIKYITAENFINEFVVHIRLDTMDELKEKFRNLDLLLIDDIQS
                     LAKKTLSGTQEEFFNTFNALHNNNKQIVLTSDRTPDHLNDLEDRLVTRFKWGLTVNIT
                     PPDFETRVAILTNKIQEYNFIFPQDTIEYLAGQFDSNVRDLEGALKDISLVANFKQID
                     TITVDIAAEAIRARKQDGPKMTVIPIEEIQAQVGKFYGVTVKEIKATKRTQDIVLARQ
                     VAMFLAREMTDNSLPKIGKEFGGRDHSTVLHAYNKIKNMIGQDESLRIEIETIKNKIK
                     "
     gene            complement(17976..18749)
                     /locus_tag="TV191_000512"
     CDS             complement(17976..18749)
                     /locus_tag="TV191_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEL1507054.1"
                     /translation="MTEILMHIPIEDIVANPYQPRLQFNQKELEELAHSIQANGLIQP
                     IIVRKSDVFGYELVAGERRFKAAKLAGLQKIPAIVKEISTLESMQQAIVENLQRSNLN
                     AIEEAKAYQLLIDKNKMTHEDIATYMGKSRPYISNTIRLLQLPDVIRQAIEDGTISAG
                     HARALLSLSTPKEQELYFHNILDQGLSVRQIEQLVKTKHPPKKRNKHKTIFVKSLEKE
                     LSKSLGLPVALSLQKNDSGQLQLSFSNQEELNRIINKLL"
     gene            complement(18869..20092)
                     /locus_tag="TV191_000513"
     CDS             complement(18869..20092)
                     /locus_tag="TV191_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HEL1507055.1"
                     /translation="MLKSKNILKPLWVLAIGFLGGLLAALVVNGFSQNSLTSSNAKGA
                     TTTSNVSFNNTTDTTKAVKVVQDAVVSVINYQKAASPAISNPYINLFGEENDTSAVQK
                     EDELSIHSEGSGVVYKKEGNTAYLVTNNHVIEGAQRIEILTADGSKIVGELVGADTYS
                     DLAVVKVAADKIKTIAKFADSTKINVGEVAIAIGSPLGTKYANSVTEGIVSSLSRTVT
                     SRNEAGETISTNAIQTDAAINPGNSGGPLINIEGQVIGINSSKISSTPTGSGGAIEGI
                     GFAIPSSDVVTIINQLESNGAVIRPALGITMVNLSNLSTNALIQLNIPTSVTSGVVVA
                     STQDGMPALGKLEQYDVITEVDGKEVSSISDLQSVLYSHEINDTIKVTFYRGTAKKKV
                     DIKLTKTTKDLTKKQ"
     gene            20302..20781
                     /gene="rlmH"
                     /locus_tag="TV191_000514"
     CDS             20302..20781
                     /gene="rlmH"
                     /locus_tag="TV191_000514"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEL1507056.1"
                     /translation="MKIKLICVGKLKEAYLRDGIAEYQKRLSRFCQCDIIELADEKTP
                     DKASHAEKQQIMAKEADRIKKKLGQRDFVIALAIEGKQLASEQFSHLLSEVTVKGYSD
                     IAFVIGGSLGLDQSIKNRANLLMSFGLLTLPHQLMRLVLIEQVYRAFMIQQGSPYHK"
     gene            complement(21081..21154)
                     /locus_tag="TV191_000515"
     tRNA            complement(21081..21154)
                     /locus_tag="TV191_000515"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21118..21120),aa:Arg,seq:tct)
     gene            21435..21506
                     /locus_tag="TV191_000516"
     tRNA            21435..21506
                     /locus_tag="TV191_000516"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21468..21470,aa:Glu,seq:ttc)
     gene            21539..21612
                     /locus_tag="TV191_000517"
     tRNA            21539..21612
                     /locus_tag="TV191_000517"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21573..21575,aa:Asn,seq:gtt)
     gene            complement(21873..24458)
                     /locus_tag="TV191_000518"
     CDS             complement(21873..24458)
                     /locus_tag="TV191_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEL1507057.1"
                     /translation="MTKPKAWSLVYDIASFLLPFLIMFFVLLSMGISYGSEKTILASD
                     GFHQYVIFAQALRNILHGADSIFYTFTSGLGVNFFALASYYLGSLLSPLVYFFNLQSM
                     PDAIYLLTLIKFGLIGLAAYFSFHRIYPKIKPFLVLTLSVSYSLMSFLTSQLELNNWL
                     DVFILLPIVLLGLYRLITQTKPLLYYSSLSLLFIQHYYFGYMVAIFIFLLFLVNLISL
                     DTWKRRLRACLSFTSVSILSALTSAFILIPAYLDLTAYGETLSPINQIIIKPIGAFDL
                     LAKLSLGAYDTTKFNAIPMIFIGLLPSLLSIVFFTLKSISWRLRLGYGLLLGLIMASF
                     YLQPLDLFWQGMHGPNMFLHRYSWSFSIIIIILACEALSRQKDITNTRIIFAFILLSC
                     LLTLPYLTMDQYSFLQPSLLILSLAFLAAYLILLLSMQKTSVPMPFLIFFTLLFSCLE
                     TSLNTYYQLNGIHHEWVFPSRKGYSRALQDIDRLVKKTADSNDQFFRLEQLLPQTGND
                     SMKYSYNGISQFSSIRNRHSSSLLDRLGYQSAGTNLNLRYQNNTLIMDSLLGIKYNLS
                     YHQLHKFGFSRIASSHHTTLYQNHYSSNLAILTDNIYKDVKLTVNTLDNQTKLLNQLS
                     GKRLTYFQLEPSKLISNAQVFNGRISGEAAENTSTTIVHYQVTVPNHRQLYLSLPNIS
                     FSNHNATAVRIRIDDQTYEYTTDNAFSFFDLGYFEKGRTLTLAIMFPKNKNISFATPH
                     FYSLNSDNYLAAMNAINQKEVTTYTRSNQVISHYKAKSEGSMIFTLPYDKGWTARLNG
                     RPVALKKAQGGFIRIDVPKGSGKLVLTFVPNGFTLGLLLSFIGILLYSFLHYYLLRQT
                     AKLKA"
     gene            complement(24581..26200)
                     /locus_tag="TV191_000519"
     CDS             complement(24581..26200)
                     /locus_tag="TV191_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1507058.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTAGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEEERAIDVVIMGNEQLYSIMKEKDAI
                     YMKPDFSEEDGVRAAELEGSFAELGGWEAESEASQLLQNLNIPEELHYQSMSELTNGD
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSISWLEDFLIDFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLFVGNYDFWKQSSELAARLQADRNAKAEEKIKELQEFVARFSANA
                     SKSKQATSRKKMLDKIELEEIIPSSRKYPFINFKAEREMGNDFVTVENLSVTVDGDKI
                     LDNISFILRPGDKTAIIGQNDIQTTALMRALADDIDYEGTIKWGVTTSRSYLPKDNSR
                     DFASDESILEWLRQFAAKGEDDDTFLRGFLGRMLFSGDEVKKSVNVLSGGEKVRVMLS
                     KLMLLKSNVLLLDDPTNHLDLESISSLNDGIKDFKESVIFTSHDHEFIQTIANHIVVI
                     SKNGVIDRIDETYDEFLENKDVQAKVAELWK"
     gene            complement(26280..27152)
                     /locus_tag="TV191_000520"
     CDS             complement(26280..27152)
                     /locus_tag="TV191_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL1507059.1"
                     /translation="MKKRVMDLLFVTIGSFITAIGFNTMFVDNNIASGGMVGISVVIK
                     ALFGISPSLFLMLSNIPLLILCYFFLGKQNLIKTLYGSWIYPIAIRLTSQLPTLTHNQ
                     LLAAIFGGIICGIGLGMVFWGNSSTGGTGILTQILHKYSPLSLGVAMTIVDGISVLMG
                     FIALSADDVMYSTIGLLVIGYVISVMENGFDSSKNVMIISKEYQAIKAYITGVMDRGV
                     SKIPIRGGYTTSDKIMLMAIVSGYELPALQEKILEIDDTAFIVVMPAAQVMGRGFSLT
                     KHYKLEDKDVLLPM"
     misc_binding    27274..27513
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            27569..28591
                     /gene="trpS"
                     /locus_tag="TV191_000521"
     CDS             27569..28591
                     /gene="trpS"
                     /locus_tag="TV191_000521"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEL1507060.1"
                     /translation="MTKPVILTGDRPTGKLHLGHYVGSLKNRVSLQNENKYKMFVFLA
                     DQQALTDHAKESEMIRESIFNVALDYLSVGLDPSKSTIFIQSQVPELAELTMYYMNLV
                     SLARLERNPTVKTEIAQKGFGESIPAGFLVYPISQAADITAFKANVVPVGNDQRPMIE
                     QTREIVRSFNHTYKTACLIEPEGLYPENEKAGRLPGLDGNAKMSKSLGNGIYLSDDAD
                     TVRQKVMSMYTDPNHIRIEDPGQLEGNMVFHYLDIFGQKEDKADIEAMKEHYQRGGLG
                     DVKTKRYLLDILERELAPIRQRRLEYAKDKGEVFRMLEAGSQKAQAVAAQTLSEVKVA
                     MGIRYF"
     gene            28792..30273
                     /gene="guaB"
                     /locus_tag="TV191_000522"
     CDS             28792..30273
                     /gene="guaB"
                     /locus_tag="TV191_000522"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEL1507061.1"
                     /translation="MSNWDTKFLKKGYTFDDVLLIPAESHVLPNEVNLKTKLAKNLTL
                     NIPIITAAMDTVTDSKMAIAIARAGGLGVIHKNMSIAEQAEEVRKVKRSENGVIIDPF
                     FLTPEHKVAEAEELMQRYRISGVPIVETLANRKLVGIITNRDMRFISDYNAPISEHMT
                     SEQLVTAEVGTDLETAERILHEHRIEKLPLVDDNGRLSGLITIKDIEKVIEFPHAAKD
                     EFGRLLVAAAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDK
                     TLIAGNIATAEGARALYDAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIYQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAASDIVFQMLGGIRSGMGY
                     VGAGTIRELHDNAQFVEMSGAGLIESHPHDVQITNEAPNYSMH"
BASE COUNT         9424 a         6201 c         5598 g         9296 t
ORIGIN      
        1 agccatagca tgcatagact acaataccaa gtatagtgct gataccaaaa gcaatccacg
       61 taaataccat atactgactc ataaaggtta cacagatgat aatagctaaa attggcaata
      121 gaggcacaaa aggagtttta aactccccac gttgaggctc tccagcgttt tttcttagct
      181 taatgatagc aaaggacatg atgacaagat aagcgagagt acagatattg acaaactcag
      241 caagactggc tagggggaat attcctgcac aaatcataga taatgcacca acaactaggg
      301 ttgcatttct aggaattctt gttttttctg tgatttgaca aagggctctt ggtaaaagtc
      361 catctctact gatactgtaa accgttcttg ctaaggcata ggtcattgaa atacaaactg
      421 taattagagt taaaatggca acaattgaga cataatctgc tgcccaatat aacccaatac
      481 tccttaaagc aaaggcaact gcatcaggta catctaattt tgtatagtga acaatcccag
      541 ttaaaaccat tgtaacaata acatataaga tcgttacaat cgttaaggat aatacaatac
      601 ctcttggaat tgttttttgt ggttctttga cctcatctac tgtcatggaa atagactcaa
      661 agcccaagaa agcaaaaaac atgactgagg ctccagcgaa aatacctgac ttaccaccat
      721 aaatttggcc aaagccataa ggcgcaaaat gtgaccagtt ggctacatca ataaaaaata
      781 agcctacaat gacaaataaa gccagagctg aaaattttaa cagaactaaa aagctattga
      841 atcgcaatgc tgcctttgaa ttcatcaata caatagcagt cactaatagc atcactagca
      901 ctggaagtaa atccacatag gtcccctttt gaggatcaaa ggtaccattt aaagcattgg
      961 gcaattgtaa gccataatta gccagtaagc cttttaaata gctcccccag ccgacagcta
     1021 cacttgaaat tgctgttaaa aattccatga tgatatacca gcccacaatc caagctggaa
     1081 attcacctaa tgtcgcatag acatagctat aagcaccacc atttgctgga attcgtgaag
     1141 caaattctgc ataaaagagt gctaatatac taatagcaat agcagataga ataatagaaa
     1201 tcgtcagcgc tggtcctgca taattagcag ctcctatgcc tgtaatagtg aaaattcctg
     1261 ttcccaccat tgatcctagg cccaaaaaaa tcaaatccag catttttaag tgcctattca
     1321 tttcagtctt attaatagct tgcctttttt tacgaaagat tgtcatcttg tcactttcta
     1381 gtcttaaaat agttctactt agtttatcat agttcctgac aattgtaaat ttcactaaaa
     1441 tgaccccaat atagcctaag acctattaaa aaacgagcta ggaccaaacc cagctcatct
     1501 tatatatcaa taatgactaa ttatttattc tttagcttct gtcattttat ccttgatttc
     1561 atcataggat aaggcatgta cctctgcttc atcgttttct ggatcatttg gcattttacc
     1621 agtctcgtaa atggacttaa tttgagcagc atccaacgtt tcatacttaa gaagtgcttc
     1681 agcaatcagc ttatgagttt cacgatgatc attaataatg tcagcagcct tgttacgagc
     1741 ttcgtttaat aaatcacgaa cctcatcatc aatcatttga gctgtttggg cagaatatga
     1801 tttttcaggt gacaattgcc ctggcatcat agcatgattg ccttcatatt ggactggtcc
     1861 aagtttttca ctcataccat actctgtgac catagcccta gccatttgag tggcctgttc
     1921 aaagtcattt gaagcacctg ttgtctgagc attgaaaata atttcttctg caacacgacc
     1981 acccataagc cctgcaagct gctccttcag atcatcttta gataaaagca tttgatcttc
     2041 ctttggaagc gcaatcatat agccgcctgc tcggcctcga ggcacaattg ttaccttgtg
     2101 cacaacacga gcattggata agactaaacc aacaatagta tgacctgcct catggtaggc
     2161 aaccatttcg cgctctctct gtgaaatgct acgatccttc ttagaaggtc ctgcaataac
     2221 acgatcctct gcctcatcaa tatcactagc atcaatttta gttttatttc gacgcgctgc
     2281 aacaagggct gcttcgttta gaacattttc aaggtctgca ccgacaaaac ctggagtttg
     2341 ttgagcaaca accttcagat tgacatcctc agcaagtggc ttatttttag cgtggacgcg
     2401 taatatcgcc tcacgcccct taacatctgg tcgaccaaca agcaccttac ggtcaaaacg
     2461 acctggtctt aacaaggctg gatctaagac atcactacgg ttggttgcag caatgacaat
     2521 gatgctttca ttaccttcaa agccatccat ctcaataaga agctgattaa gggtttgctc
     2581 acgctcatcg ttaccaccac ccatgccggc accacgacga cgaccaacag cgtcaatttc
     2641 gtcaatgaaa ataatcgctc gctcagcctt tttagcatct tcaaataaag aacgcacacg
     2701 actggcacca acaccaacaa acatctcaac aaaatctgag cctgaaatgc taaagaatgg
     2761 tactcccgcc tctccagcaa cagcctttgc aagcaatgtt ttacctgttc ctggaggtcc
     2821 ctccaaaaga acaccagcag gaatgcgcgc accgagtgcc ttgtatttct taggattctt
     2881 tagaaaatca acaacctcta ccagttcttg tttttcttcc tcagcaccag ccacatctgt
     2941 aaatctaacc tttacatcac cctttgcttg tgatctagcc ttatttttac caaaactcat
     3001 ggcaccacga gcaccaccac cttgattcat gatcatcatc atgaaggctg caaaaatcac
     3061 aatcggcaga aagctcataa gaaaggtaat ccaagcccca cttgagcttt cttgttttac
     3121 agtaatgtct gttccatttt tatctgcgac agaagtcatt tcctttaata cagaatcaga
     3181 tggtaaaatt aaggccgtaa attctgttac ctcagtggct gcactattac ctaaaaatga
     3241 caagcctgtg tcaatagaca ccttttgagg cttttcatat tttcctttaa cctcaacaat
     3301 gctgccacta ggctgatagc taagtgattt aatatcacct gccttcaaat gcttaattaa
     3361 ttttgaatag ctaatttgct ggctttgtgt actagttcct cttaagtaat attgaaatcc
     3421 tgctacaaca ataacaatca tcaatatata tataaaagaa tttttgacaa atccattatt
     3481 tttattattt ttcatacaac aataattgac cttttcctat tttgaataga cttcctcttt
     3541 taaaacaccg acataaggga gatttctata attttctgcg taatctaatc cgaagcctac
     3601 aataaactca ttaggaacat tgtagcacac atagtctgcc tcaatgtcta ccacacgacc
     3661 ctctggcttg tcaaatagtg tgataatctt aacggaatta gccttacgat atttgaacat
     3721 gtcacgcaaa tatttgagtg ttcgaccagt atcaataata tcttcaacaa agatgacgtc
     3781 tcttccctca atattggtgt caacgtcttt taagatttta acctctccac tgctagttgt
     3841 tccaccatta tagctagaaa caaccataaa atcaatttca acgtgagtgt caatgtgctt
     3901 catcagctcg gccatgaatg gaacagaacc ctttaagaca ccgaccatca agggattttt
     3961 accatgataa tcctttgtca actgctcacc aagctccttg gtcctttgaa taatgtcatt
     4021 ttcagaataa agaatttttt gaatatcttg ctcaagcata ctgtcacctt ttttctaatt
     4081 tatcaatata cagtttagcc aacattatat catgtttaga cgcttttctc aaatatgttt
     4141 catcaccaac cagcacaaaa ataataactc cagcctgttc tcctacgatg gcattttgac
     4201 gctgctcact tgtaaacttt ccatcgatga ataaacgtct taattttttt gaaaattcac
     4261 caagaaaaag cctatctcct gcctgcctat gacgtaaagt aactggtgat aagctatata
     4321 aagggatagc tatatcatgt cccttatcag tcaaactacc tgagaaaaca aatcgatacc
     4381 ctctataatt tagggaatca ccgtatgata ccattttaaa ttctcgattt aaatcagtct
     4441 ttggaatgat ttttttaata gcaaaagact ctttttcaat gaggagacaa taagtatttt
     4501 taattggata aatcccctgc ttttgtcgtc tgatgatgtg taaaagatca tcaaattgtg
     4561 attttttaat ggctagctgt ggaaacgttt ctaaataatg ctgaagcaaa aaaaactgaa
     4621 cagcagctga ttgagctaaa aaacagttta atcgatgaaa ttcaagtccc ttggttaaat
     4681 catcaaaggc ctgaagcagc aggcgacttt ccgcagataa atcaatcaaa gattgagtag
     4741 cttgaggatt ttctcttttg aaatctggca ggtaatgatg acgaacacga ttgcgaaaat
     4801 aagccatgct gtcattagaa tgatcttcaa aatgaaaggg attaggcagt tctgcttttg
     4861 ataccgttaa aaacggtcgt atcaactgac cattagcaaa gggctgaacc tctctgatac
     4921 cagctaaatg acgcaatcga ctaccacgaa tcagtctcat caaaatagtc tcagcctgat
     4981 catcagcatg atgtgctgtg actaaagccg aataatgctc ctgctgcatg atctcttcaa
     5041 aaaattgata gcgaagatga cgcgcagcat tctcagaaaa agcgccctga aaataagcaa
     5101 catagatagg aatagcatgc tttttagccc aagacctcaa ataagcctct tcgtcatctg
     5161 attctggtct ttgcttgtga ttgacatgcg caatgccaat ccgaatttgc aattttgctt
     5221 gaaaagcatg caaaaagtgc agcaaattca tcgaatctac tccaccagat acagctatca
     5281 aaacagcctg atgagcgtca aaataggcct tcttttttat gatgttataa atgtgttgat
     5341 aagtcatttt aaaatcgaat aaacatcgtc agcaattgct gtgatgtcgt cataggaagc
     5401 cttatctgta aaaacggata agataaaggg attatcacca taaacaatgg caacatcatg
     5461 cttgtaatcg taggcgtctc caatcttgtg agccactggc acagaaatat tttttgaaat
     5521 gcgctgatca tcaaatgccg tctgtgacaa ataagaaata atctgacctt tttgataata
     5581 gatagcttcc atgagatttg ctgctgcatg agaagaaagc aagcgctttt ccatgtccca
     5641 atctactcca gctaaagccc taatctctga ttgaaaggct tgattatatt gattacatag
     5701 gtagtagcct aagatattag tagcaacatt gtcagactgc tgagccacag cctttaaaag
     5761 ctccatcaca ttatagtcct ttttgtcagc tgttttactg attttaccac tgccagttgg
     5821 atcgtaatca ccataaaaat gattgacctc atcaatgtat tttaagctct taccttcaga
     5881 taagctacct gacttcagtt ttttttgaac actgtacagg gttgctaatt tggaaatact
     5941 tgccgcatac atctgtttat cagcattgat acctgcactg gcctgcgtgt taagctgctt
     6001 tacaaaaata gaataattct ctttattata tttttgcaat agcatttcct gaaccttcaa
     6061 catgcgattg tcggtaggtg acaactcctt ttgattaacc cagcccttat gatcaatgaa
     6121 ataataggtc ccatgctctg tttgagccat cttactagca tgaacctttc tgccaggctc
     6181 actatctgat gcaattgtct taacacctaa aacatagggt tcagcatata tagtcatctt
     6241 tttttgagtc caaaaatcca aatccacagc tgtctgctca aacataatat cctcgtaaac
     6301 aatctgacga ctagcttcaa ggtaagtgtc atctgccagt ctaaagacag gaatagctgc
     6361 cttgtttagc aaaacatcct tgataacaat tctattgtct ggtgcgatca tcgtctttgg
     6421 cacactcaat tcgggatccc tataagcaac tgtctcctca aaaacattgg gattagtcgg
     6481 aatccgacta taataaagag tggagctaac aatatcctga cttaagtgat agcgtgtcgc
     6541 ttcagaaaac actgggattt tttctgtact aatgaccgtt aaaggagtca cgaaaaatgt
     6601 cattaacata gctgctaata attttttcac aatggctcct tcctatttta cttctgtgcg
     6661 atgatggtct ttcttcagct cttgattttc cttttctagc tctgctaatt tgtcatcaga
     6721 aaaggcaaga aaggtttcaa ttttttcgac aatattatcc atagtcaatt actattttgg
     6781 taataatcca ggagttggat aaataacctc tccttctctt gataagtaat atttagccct
     6841 agcatacttt ttgacaaaat catcattttt tagctgctca gctaactgct tttcagactt
     6901 agtctttttt tctaactcac gatactcttt ttccaacgta ataatctgct gaccttgttt
     6961 tttcagtgaa acataaccct taaccaagtt ataggttggc agaataaaca agaacatcat
     7021 actaaccaag atccaaccca taaaacggtt ccgtttttgg atttcctctt cctcaaaccg
     7081 ttttttgata ttttcttcgt tgatataatg gttattcaac tggacgatac taggcttctt
     7141 catcgctact tatccttgtt tcgctgataa tgtcatacat tttagcagcg tcctcttttt
     7201 tagtgctatc cttcatatca agcacacgaa cagtaagcaa cttattgcca aacctgattt
     7261 caacctgatc atttagtttt aaatcagttg agcttttcgc aaggatacca ttaaccttaa
     7321 tacgtccctt atctgcgact tctttggcca ctgatcgacg cttaatcaat cttgatacct
     7381 ttaaatattt atctaatctc atatcttttg cctcacaatc cctttcattc tatcattttt
     7441 ctttgacaaa tggtagaaaa gaccacaatt tctctttaaa gacacctagc tttttgcaag
     7501 ctattaaaaa agaggataaa ccaacagcag atgacaccaa aagactaatc agcgcaccaa
     7561 gtcgacctga taatggcaag caatactgac ttgtaagcac acacatgagc atgatcacta
     7621 aagcaagccc atatttagca ttcactatcg ctttaaaatc aatatcagcc agcacagcat
     7681 acaagagtaa aacgaccagc aaggggatta gggtggataa ggagcttcca acaatagcgt
     7741 aatagtaggt taatataggt gttaagccta attttaataa aaagccaaac agcaaaataa
     7801 gcaaagattg cttgatgtga tcctcaatga agcatttttg atgaaagaat tgaatcatgc
     7861 ttgatactgc tataatcatc aggtaaacca ctaaggccag ccagccctta ttgtcctcaa
     7921 ataaggctcg attcatcaga tggagaatac taataaaacc aacagtcagt gttaaactaa
     7981 aataaaagat aaactcaaag aaacattgac tttgctctct ataggactcc cttttaatat
     8041 gaaacaagac tgttaaattc ggtaaataag ctgtaaataa ggccgtcgaa aaaatgagac
     8101 caaattgcag caagggctgt cccctatcgt aaacaccctt agtcatttca gctgttatct
     8161 ctgataagcc tgagctaacc aaaatatttt tcaccaaaag agaatctatc aattgaaaaa
     8221 caagcaggta aattgaaaaa agtaaaaaaa ctaaggtcgg caagcccaga cttgttaaat
     8281 ctctaatagc aaccgtatct cctgataaaa agctttttaa tgaataagca ctatgacgct
     8341 tcaaataagc taaaataact aagctcgcta ctaaatttcc aaaagcagca acatttgctg
     8401 ttaaataaac cgtccaacca agcaccctgt agcatagtgc agcaacaatg attatagcaa
     8461 ctcttatgat ctgctcaaga acctgactca gagctgtagg agccatattc atatcagcct
     8521 gggctaagcc tctgtaaaag gatataaagg gtactattaa caaaaccatt gctgttataa
     8581 caattgatgg tgccaactgc tgtgctccca tccagctagc caatgcctta tgacttagca
     8641 ccaatattcc tgacaataag aagctggtat agcattgcaa cttaaataga gctgctagct
     8701 gtagctgctt ttttttctgg gccatactgg caatcacatt gggtaaagca gttagaccta
     8761 aggctgaaat aatacctagc aaaggataga tttgttggta agcataaaag cccctatccc
     8821 ctaccaaatt ttgataaggg atacggtaac tggctgctaa taattttgac ataaaaccac
     8881 taataacaat cagaagactt gattgcttag ttttatgagg aagcttttct agatttaatc
     8941 tcaccaagtg tctctccaaa aagtatcaat tcttctaaaa tgacatggtc tttctgacgt
     9001 ctaacatcaa agataatttc aattttaccc tgatgctcac taatccttgc ttttaagctt
     9061 gtttttgaca gagcctcaaa ataatcctgt gtcaaatagt attgaagcga agcaacctca
     9121 aacctaacca taacctgatg gtccctcttc tcgactaatt cagcaaaggc tgtatccaag
     9181 tagtatttca acaagccaat ctccagtaaa taggctacct gatcaggata gtcaccaaaa
     9241 cgatccatga tttcatcttg caaatcagaa taagctgctc tagagtcaat ctcacgaatg
     9301 cgcttataaa tgtcaatttt ttgacgctcg tctttgatat aatcactagg taaataagca
     9361 tcaatatgca gattaatctc tgcattacct ttttgtcgcg tcaatgctct tccttgcttg
     9421 cttgcaatag cctgctccag cagctgagaa tacatgtcaa aaccaactga gtcaataaaa
     9481 ccactttgtg aagcacccaa tatatttcct gctccccgaa tagataaatc tcgcatagca
     9541 attttaaagc cagatcccag ctctgtaaag cccttaatag cttctaacct tttttcggaa
     9601 acctctgtta gtaccttatc aggcttatac atgagataag cataggcaat acgattgctc
     9661 cttccaacac gacctcgaag ctgatacaaa gttgatagtc ccatatgatc agcattttca
     9721 ataaataagg tattgacatt agaaatatca acccctgtct caataatagt tgttgcaact
     9781 aaaacatcat aatcaccatt gataaaatcc atcaaggtat tctcaagctg aatgtcactc
     9841 atttgaccat ggacaaaacc aatagaagcc tctggaacca attcttgcag ctctgccacc
     9901 ttcttgtcaa cagtgtcaac cttattgtaa acataaaaga cttgaccacc acgatccatt
     9961 tctcgaataa tagcttccct aatcaagcca ggattatttt ctaaaacata agtctgaaca
    10021 ggatagcgat tcgtaggagg cgtctcaatc actgataaat cccgaatacc aagcatagac
    10081 atatgcaggg tacgaggaat aggcgttgca gtcagtgtaa ggacatcaac cttggtcttt
    10141 aattccttta gggtttcttt atgcttaaca ccaaaacgct gctcttcatc aatgacaatc
    10201 aagcctaaat ctgaaaaaat cacatccttt gacagcaacc tatgagtccc aataataata
    10261 tcaacctgac ccttttttag cctttctaga ctttcagatt gctctttttt actgcgaaag
    10321 cggcttaaaa cagcaatttc aaccggatag ttctcaaatc tttccctaaa attctcataa
    10381 tgctgctgtg ctaaaacggt tgttggtact aagatagcta cctgcttatg gtcaccgata
    10441 gccttaaaag cagctctcat agccacctca gtcttaccaa agccaacatc accaactagt
    10501 aaacgatcca taggtctgac actctccatg tcttttttaa cctcttttat ggacctaact
    10561 tgatcatcag tctcaacaaa ggcaaaatcc tcctcaaatg ctctttgtaa ctcatcatct
    10621 ggagaaaact gaaatccttt ttgctgactc cgctctgcat aaagcttcaa caggtcatct
    10681 gcaatatcct caacttgctt tttaaccctt tgctttgctt tttgaaaacg accatcgttt
    10741 agtttattaa tctttggctc tttaccatct gctgatacat attttgataa gctttcaagc
    10801 tgatcaacag gcaaagaaat tcgatctgac tgctgatact gaatggtgac ataatctcga
    10861 tgtacccctt gtatgttaat cgtttcaatg cctaaaaaac gaccaatccc atgcacactg
    10921 tggaccacat aatcaccctt agacaattca ttgtaatcct ttaagcgttc agcattactc
    10981 atattagtac gacgagcacg acgcttcagc ctcttatgat atatctcatg ctcagtaatt
    11041 aaaactaatt tttcatcagc aaagtaaaac ccacctgcta ggtgaccaat aatgatttgt
    11101 gcttgatgta atactattgc atcagcagaa acaaggggca attgacattg ataagcctca
    11161 agagattttg ccaaccgctc ataagcttga tgagattcaa cctgtaaaag gacagttgct
    11221 ccagattttt gataccgctt aatctcatca atgagcagtg gaaattgatt gaaaaattcc
    11281 tgcatggcat actgtgttaa gctatacacc ttatcaaatt taatattacc aagtcccttg
    11341 tgaaaatttg aaaagaaggt ggcaggctta tagtgtcgca gctcacgata attgtcagca
    11401 aaataatgga gaaatggaag tgactttcct tgctgtaaat catctgtcaa caaatgagca
    11461 agctctaagt caaatttagc atttctgtca actaactttt ggaaatcatc aaaaaatact
    11521 ggtgttccct taggaaggta atctagaatc gtccattcat tatcataaaa cagtgattga
    11581 aatttacgga tgtccttatg cttcaggcct tcttttgtta cagtgagcaa ctcctccaga
    11641 tagcctttat gttctgcctt agcaagttga agctgctttt caagattatg actagcccta
    11701 tcaaaatcct ccggctcaaa aatcatatca cttgcaggct tgatactggt gctatccttc
    11761 ttttggagag atttttgact ttctatatca aagctcctaa taccatcaat ctcatcacca
    11821 aaaaattcga tgcgaacagg taagtcctgt gttacctcgt aaacatctaa aatatcacct
    11881 cgtctgctaa attcaccagg actaaggacc tgagccaccc tttgataacc aattttgaca
    11941 agcttcttga caacgttgtc aagatcagtg tcaactccta ctgctaagtc aatctgcccc
    12001 tgctgaaaag tcttaggact tggaagtagg attctgagtc ctgctaagct aatgaccaat
    12061 attcctcttg cttctggatt tgataaaaaa gctagtgcct ctattctcga gattgtttta
    12121 tccatagagg agaaaataaa ctcagccgca gcagtatcat ctgcaaaaaa ttgaaaaata
    12181 gagccctcat caagcaaggc tgacaaatca ccagctaatt tttccatgtc attttgagtt
    12241 gatgtcacca cgaccagctt cccttgaaag ctaagatagg ctgaggcaat ggctgctgct
    12301 ttacttgagc ctgacaagcc catgactaat tgccgtttta agcttgttac atcacattgc
    12361 caggtctgga ttgacttgtt ttgattaaat aattctaaaa tatccataac tacccattaa
    12421 attgctgcat tgttttctca atgctttttt cctgtaaata atagttgatt gctttgtcaa
    12481 ccttatcaag tgctatattg attgttatca tatcatctgt atcaaatttt cctagaacat
    12541 gattaataac actcattcca tgacttggtc ttccaatacc aattttaacc ctatcaaatt
    12601 cctgtgtacc gatatgagca ataatggatt ttataccatt atgtccccct gcagagcctt
    12661 tttgacgcaa acgaatttta ccaactgcca tatctaaatc atcatagatg accattaaat
    12721 ctttagttga aatattgtaa taggtcaata aagccctaac agcaagacca ctattattca
    12781 taaaggtagt tggcttaaca aaataaatct tttcttgatt gataaaagta ctcccaataa
    12841 gggctttgaa ggttttatct tctgtaaagc taacgtcaag atccttgaca agtctgtcaa
    12901 ctgccataaa accaacatta tgctttgttt gctgatgttt tgagcctgga tttcctaatc
    12961 ctacaatcat ttttaccata ctaatacacc agagaaacga ggtatgatag cagcctgttg
    13021 accattctta aagctttatc agcctcttcc cctctatttt ttgtcctttc taagcttttg
    13081 ataggcacca aaagggctgg aatactatcc caaccctaga acacaatatt gttaccacta
    13141 aacattgaat ctaaattcca taatatcgcc atcctgaacg atatattcct ttccttcctc
    13201 acgcagacga cctgcctctt taacagcctt ttctgagcca tacttaatca aatcatcata
    13261 gctcatcgtc accgcacgaa taaaaccgcg ctcaaaatct gagtgaatga taccagctgc
    13321 ttgtggtgcc ttaataccgc gcttgaaggt ccatgcacgc acttcctttt caccagctgt
    13381 aaagtaggtg ccaagtccaa gtaaatgata ggctgcacgt gtcagcttgt caacgccaga
    13441 ttctgtcaga ccgatagctt ctaaaaattc actcctgtct tcatcatcta actctgaaat
    13501 ctcttcttct gcacgagctg aaatcacaac aacctctgca ttttcagttg ctgcaaagtc
    13561 acgaatctgc ttcacataat caatagcgtc tggaattgct accttatcct catcaacgtt
    13621 tgccacataa agcactggct tagtcgttaa taaaaataac tgcctaacaa ttttttgctc
    13681 atcatctgta aagctaatgg tacgagcaga tttgccttct tcaagcactg gcttaatttt
    13741 ttcaaggaca gcaaattctg ctacagaatc cttgtccttt tgtgtacggg ccattttttc
    13801 gacacgcgca tagcgtttat tgattgattc taagtcagcc aaaattaatt caaggttaat
    13861 cgtatcaata tctgccaaag gatccacaaa ggcatcctca cgcccctgct cacgcatgac
    13921 attttcatca tcaaaggcac gaaccacatg aacaatagca tcaacctcgc ggatattggc
    13981 taagaactta tttccaagtc cttctccttt tgaagctccc tttacaatac ctgcgatatc
    14041 tgtaaattca aaggttgtag gtactgtttt tttaggcgtg ataagctctg tcaacttctg
    14101 taaacgctca tctggaacct ctaccatacc aacattagga tcaattgtcg caaaaggata
    14161 attagcagcc tctgcccctg cttttgtaat tgcgttaaat aaggttgatt tcccaacgtt
    14221 tggcaaacca acgatgcctg ctgttaaagc catatttttt tcggtctccg ttacattttt
    14281 tcaatcctta tcattatagc aaaaaaaaga agaaaaagct tgcctagtaa tgatctttaa
    14341 ctaaaatgga tcacaataaa atacacacct aacaaaacga tcacaaccaa taatagcata
    14401 agaagatcgc ctttacgcat tggccgctta gattcctcag ttaaaaattc ccatacgttc
    14461 attggctttt cagttttctt aataaccttg attgcaggtt cttttccagt caccaattca
    14521 tctaaagtta cctctaaaac agctgccaat gtaactaaat tttccaaatc cggtgtcgca
    14581 tctccatttt cccactttga aatagcctga cgggagatga aaagcttctc agctaaggca
    14641 tcctgagaca actgcttttc aagccgatac ttctttaatt gttctgcaaa tttagtcatc
    14701 attaatgacc gcctttcctt tttgatagct ttacaataac tcttttttaa aaggcaagct
    14761 agcaattttt aacgcaataa tgagttgcga aggtagttaa aaaccttatg acaatagagc
    14821 ttctatggtt gcagaacctt cttcatttta cgctcaaaat catgacgact tagcatgata
    14881 acatgattac agttagtgca ttgcagctta atatctgctc ctactcttgt gattttccat
    14941 tgatttgcct tttttcctgt ttctttaatg acacaggcat ggggcttttt catttcaatt
    15001 aaggatccaa cttgatacat cactttatca ctcactcatc tcttatattt attatttatc
    15061 ataacaaaaa aagcccccaa aagggagcgt ttttcgctta gtttgtacga actggtgtga
    15121 ttaattgaat aaagctctct tcatcatctc ccggtgttaa ggtgaaagga cgaacaggcg
    15181 ataggaagtg aatcttaacc gtctcacttt taatggcttt taaggcttca atcagatagg
    15241 ttgggttaaa gctaatggtt aaatcattcc ctgcttgact caccacgtcc agatcctcgt
    15301 taaccttacc aacctctgga gagttaacat gagctgaaat gcgatttgct tcaatttcaa
    15361 gcttaacagt accattttgc gtagcgtttg aaatcaagaa agcacgctcc atagcatgtc
    15421 gtaaggattg tgtgttaaaa acagcctctg tctcaaactg cttcatcagc aaacgatcag
    15481 tatcagggta attaccttct aacagacggg tgtaaaaaga aatgtagtca cttctaaata
    15541 gcatttgact agcagaaaag aacacttcaa cggtttctat atcatctgta aagacagctg
    15601 aaaattctct caaggattta cttggaataa ccacatcaaa atcagctgag gttttctcca
    15661 gagtaatcaa gcgctggctc atacgatgtg aatctgttgc caccgcttta aagttcttat
    15721 gctgacttag ggtgatgtgt acgcctgtca aaataggacg actttcctgc atactagcag
    15781 caaaggctgt ctcagcaatg atagatttta agagtcttgt atttaaaatt aaaggatttt
    15841 cagttgatac ctcttgaaga cgtgggtatt gagaaacatc cttccccttt aaggtgattt
    15901 cagatttccc actggttagc accacctgat gctgttcaat ttccttaaat tctaagctaa
    15961 catctggaag acttgagata atattgataa aaaagctggc ttctaaaaga acagcccctg
    16021 ttgaggttat caacaagcct gcgttttcat tgctaacagg aatggtattt tcaatagaga
    16081 tttgaccatt agagccagtc agggtaatgt ctgatggatt aacctcaatc ttgatggttg
    16141 ataagatcgg tatagcattt ttactgctga tagccctttt agtggctgtt aaagcttgaa
    16201 tgaaaagggc tctattgata gaaaattgaa tcatggtaac tcctttgtta tataagtatt
    16261 atagctagta gtagtagtag gtcttgttaa aatagtggat aagtctcctt gtactagtcg
    16321 ttactagtta aaacgcttgt gcacaagctg tggataaatt ttcctttttg ctaaaggtta
    16381 tccacattgc ttatttgatt ttgttcttga tggtttcaat ttcaattctg aggctctcgt
    16441 cttgtccaat catgttttta attttgttat aagcatgaag cacagttgaa tgatcacgtc
    16501 ctccaaattc tttaccgatc tttggcagac tgttatcggt catctcacga gctaaaaaca
    16561 tagcaacctg tctagcaagc acgatatcct gtgtgcgttt ggtcgccttg atttccttaa
    16621 ccgtaacccc ataaaatttt ccaacctgag cttggatttc ttcaattgga atgacagtca
    16681 tcttaggacc gtcttgcttt ctagctcgaa tagcttctgc tgctatgtct actgtaattg
    16741 tatcaatttg tttaaaatta gccacaagac taatatcctt caaagcccct tccaggtctc
    16801 tgacattaga gtcaaattga ccggccaaat attcgatggt gtcctgagga aagatgaaat
    16861 tatattcttg aattttattg gtcaaaatag caacacgtgt ctcaaaatca ggcggtgtga
    16921 tattaactgt tagtccccac ttaaatcgag ttactaggcg atcttctagg tcattgaggt
    16981 gatcaggggt tcggtcactt gttaaaacaa tttgcttgtt attgttatgt agagcattga
    17041 aggtgttaaa gaactcctct tgtgtaccag acaaggtttt tttagctagg gattgaatgt
    17101 catcaattag gaggagatca agattgcgaa atttctcctt tagctcgtcc atagtatcta
    17161 gacgaatatg aacaacaaat tcattaataa aattttcagc cgtaatgtat ttaatcctag
    17221 catttggatt ttccagtaaa actgaatttc caatagcatt taaaagatgg gtcttaccaa
    17281 gacctggacc tccccagata aataaaggat tataggttgt tcctggtgta ttagctaccg
    17341 ctattgatgc agcaacagcc cacctatttt catcaccttg gataaagttg tcaaagctgt
    17401 atttagggtt tagatcggac tgtactgctg gtaattgctg gaaggcttgt tcagtatatc
    17461 cttgctgtcc ctgatgctgt tgctcaatca tcaagtcatc ctcatagaca tagtctacag
    17521 caatttgagc attgtaaact tcaaatcctg ctgttaggat aacgtctttg agattttttt
    17581 cccaaaacaa ttccttcatc tgatctaaaa aaattgttgc gacatgattg tctaccttga
    17641 tcaaacgagc atcatgaaca aaaaattcat aagttgcctg ctttaactgg ctttgagcta
    17701 gctctaagac cctattccaa aaaatttgtt cattttcagt catacgagat tccttcttgt
    17761 ggataattct agaaccattc tatcataaat aaagatagtt ttccacaaag gatcaaggat
    17821 tattttagac ttacccacaa gctgtggaga taaaatacac aatgtgtaag atagttttcc
    17881 acaacttgtg gaaaaaagag aaagccttgt gataaaaggt tttagcccca tttctcttgt
    17941 ggaaaactga ataaaaaaaa cagacaatca acaagctaaa gcaacttgtt gataattctg
    18001 ttcaattctt cttggtttga aaatgacagt tgcagctgcc cactgtcatt tttttggaga
    18061 gacaatgcca caggtaatcc taatgatttt gagagctctt tttctaaaga cttcacaaaa
    18121 atggttttat gtttgtttct tttttttggg ggatgcttag tctttaccag ctgttcgatt
    18181 tgcctaacgc ttaagccttg atccagaatg ttgtgaaaat aaagctcctg ctcttttggt
    18241 gttgacaagg ataataaagc tcttgcatgg ccggcgctaa tggtaccgtc ctcaatcgct
    18301 tgtctaataa cgtctggtaa ttgcagcagt ctgatggtgt tgctgatata agggcgtgat
    18361 tttcccatgt atgtcgcgat gtcctcatgg gtcatcttat ttttatcaat aagtaattga
    18421 taggccttag cctcttcaat agcatttaaa tttgagcgct gtaggttttc tacgatggcc
    18481 tgctgcatgc tctcaagagt agagatttcc ttaacaattg ctggaatctt ttgaagtcct
    18541 gccagcttgg ctgctttaaa gcgtcgttct ccagcgacta attcatagcc aaatacatca
    18601 gattttctga caatgattgg ttgaatcaaa ccattagcct gaatggaatg tgccagctct
    18661 tcaagctctt tttgattaaa ttgaagacgt ggttgataag gatttgccac aatatcctcg
    18721 ataggaatgt gcattaggat ttctgtcata taagcctctc aaaagggaaa tagtggtagc
    18781 ttaacggtta ttagagatac atacgggata aaagagcaag agcccgcgac catcgtctcg
    18841 gactcaatct cacggggata cccaatgttt actgcttttt agttagatcc ttagttgttt
    18901 ttgttaattt gatgtcaact ttcttcttag cagttcctct gtagaaggtt accttaatgg
    18961 tgtcgttaat ctcatgacta tataagacac tttgtaggtc actaattgag ctgacttctt
    19021 taccgtcaac ctcagtaatg acatcatact gctccaattt accaagagca ggcatgccat
    19081 cttgagtaga ggctacgaca acaccgctgg taacgcttgt tggaatattc aattgaatca
    19141 atgcattggt tgatagatta cttaagttta ccattgtaat gcctaaggct ggtctgataa
    19201 cagctccgtt agactctagt tggttaataa tggtgacaac atcgcttgat ggaatagcaa
    19261 agccaattcc ctcaatggct ccgccgctac cagtaggtgt tgaggatatt ttacttgagt
    19321 tgataccaat aacctggcct tcaatattga tgagtggtcc acctgaatta cctggattga
    19381 tagcagcatc agtttggata gcatttgttg agatggtctc gcctgcctca tttcttgaag
    19441 tgactgtacg gcttagactt gaaacaatcc cttctgtcac tgagttggca tattttgttc
    19501 caagaggact accaattgca atggctacct ctccaacatt aattttggtt gaatctgcaa
    19561 atttggctat tgttttgatt ttatcagcag caactttgac aacagctagg tcagaataag
    19621 tgtctgcacc aactagttct ccaacgatct tagagccgtc tgctgttaaa atttcaattc
    19681 gttgagctcc ctcaataaca tgattgttgg ttacaagata agcagtatta ccttcttttt
    19741 tgtagacaac acccgaacct tcactgtgta tgcttagctc gtcctctttt tgtactgctg
    19801 aggtatcatt ttcttctccg aaaagattga tgtaaggatt tgaaatggca ggcgaagcag
    19861 ccttttgata gttaataaca gacactacag catcttgaac caccttaaca gcctttgttg
    19921 tatcagttgt attattaaag ctgacgttgc ttgttgtcgt tgctcccttt gcatttgaag
    19981 atgttagaga attctgacta aatccattaa caactaaggc agctaataag ccccctaaaa
    20041 atccaatggc taaaacccat aagggcttca atatattttt tgattttaac acaaaatcac
    20101 ctccgaatgg ttttcacata ggatataaaa cctcacttaa ttatacctta aaaccataaa
    20161 aaagaaaagt aatccacaac ttgtggaaaa cttttcagga ctatactaaa aaggctgtag
    20221 aaaagggttt atataaagaa aataagaaat caacatgtgg ataagttgtg taaaaagagt
    20281 tgattatggt acaataagga tatgaaaata aagcttattt gtgtcggaaa attaaaagaa
    20341 gcgtatttaa gagatgggat tgcagaatac caaaaaagac tgtctcgctt ttgccaatgt
    20401 gatatcattg aattagcaga tgaaaaaaca cctgataagg ctagccatgc tgaaaaacag
    20461 cagattatgg ctaaggaggc tgacaggatc aagaaaaagc ttggtcagcg tgattttgta
    20521 attgctttgg caatagaggg caagcaattg gcatcagaac agtttagtca tctactatca
    20581 gaggtcactg taaaaggcta ttcagacatt gcctttgtca ttggtgggag tcttggtttg
    20641 gatcaatcca ttaaaaatag ggctaattta ttgatgagct ttggcctatt gaccttacct
    20701 catcaattga tgcgtttggt tttaatcgag caggtttatc gtgcttttat gattcaacaa
    20761 ggcagtccat atcataaata gcagttgttt cacatgaaac actacacatg gcatagaaga
    20821 agcgcgtgta tacctcaacc atacttctag ctttcattaa tagggctgtt gatttgcagc
    20881 cttactcagc tattgcctga tgataaaagc attaattgct ttatcgaact gatgatttgg
    20941 aggttttgtg attttagcct tagacgatgt caggcaaatg cttatcactc ttatgactct
    21001 cctacgggag tcagtagctt actattgtta gaaatacaaa aagccattag atactgacta
    21061 atggcttttt ttactatttc tgatctcagc aggattcgaa cctgcgaccg ttcgcttaga
    21121 aggcgaatgc tctatccagc tgagctatga gacctcaacc accttatttt aacaaaaaaa
    21181 ccttatgcct gtcaatgctt atttttgata agaagcttca ctgccctaaa cgtgcggtga
    21241 tatgtctttt agcagtttgt atcagaggag caatgtgtta tgttttctag catgtttggg
    21301 gtaattagac ttgttttaga ctgtttatgt caaaagtgat caaaaaatca agattttttt
    21361 gaaaaaagta tagacaaata aaaacattct gctataataa taagagtgtt aaggagagtt
    21421 actcctgaac ttcaggtccg ttggtcaagg ggttaagaca ccgccttttc acggcggtaa
    21481 cacgggttcg aatcccgtac ggactatcag aattgtcttt gtggcaattt ttttattttc
    21541 cggcatagct cagttggtag tagcgcatga ctgttaatca tgatgtcgta ggttcgagtc
    21601 ctactgccgg agtgataaga cacttcctaa ggctttctta ggattttttt attgaccttg
    21661 aagagtgatt gtgatttgct aagaaactta aaaatacgct aatcgtctaa atgataggct
    21721 tctctttttt gggactaagg aacacgtgag ttatggaaag tcatgtgttt tgataaatat
    21781 ccttaaatca atagaccagc taaaaacact tgattttgat acctggaagg gctgtaaaat
    21841 caagcgtttt gcttatatat ggaaattgct gtttaagctt ttagcttggc tgtttgcctg
    21901 agtaagtagt aatgtaagaa gctgtaaagc aagataccaa taaatgagag cagtaagcct
    21961 aatgtaaagc catttggaac aaaggtgagt actaatttac cagatccttt tggaacatct
    22021 atcctaataa aaccaccttg agccttttta agagccactg gtcggccatt tagtcttgct
    22081 gtccagcctt tgtcataggg aagggtaaaa atcatagagc cttctgattt ggccttgtaa
    22141 tggctaatga cctgattgct acgggtgtaa gtagtaacct ctttttggtt aatcgcattc
    22201 atggctgcca gatagttgtc actatttaaa ctgtagaagt gtggggtagc aaaggaaata
    22261 tttttgtttt tcggaaacat aatagcaagg gttaaggttc ttcctttttc aaagtaccct
    22321 aagtcaaaga atgaaaaagc gttgtcagta gtgtactcgt aggtctgatc atcaatacgg
    22381 atcctaacag ctgttgcatt gtgatttgaa aagctaatat ttggaagact taagtagagc
    22441 tgcctatggt ttggtacagt aacctgataa tgaacaatgg ttgttgacgt attctcagca
    22501 gcctcccctg aaattctccc attaaatacc tgagcatttg atattagctt agaaggctct
    22561 agctgaaaat aggtgagcct ttttccactc agctgattca gcagcttggt ttgattgtca
    22621 agtgtgttga cagttaactt gacatctttg taaatgttat ctgttaagat agctagattg
    22681 ctgctatagt gattttgata gagtgtagtg tgatgactgg aggctatcct tgaaaagcca
    22741 aatttatgaa gctgatggta gctaagattg tattttatcc ctaaaagact atccatgatg
    22801 agagtgttgt tttgatagcg aaggtttaga tttgttccag cagactggta gcctagacga
    22861 tccagaaggg agctggagtg acgatttcgg atagatgaaa attgagaaat gccattatag
    22921 ctgtatttca tactatcatt gcctgtttgt ggtaggagct gctccagtct gaaaaactga
    22981 tcattgctat cagctgtttt cttgacaagt ctgtcaatat cctgtaaagc tctactatag
    23041 cccttacgtg atggaaacac ccattcatga tgaatgccat taagctgata ataggtattt
    23101 aaactggttt ctaaacagct aaacagtagg gtaaaaaaga ttaaaaatgg cattggtaca
    23161 gaggtttttt gcatgcttaa caataaaata agatatgccg ctaaaaaggc aagacttaag
    23221 atcaataaac taggctgtaa aaagctatac tgatccattg tcagataagg aagtgttaat
    23281 aagcagctta ataatataaa ggcaaagatt attctagtgt tagtaatgtc tttttgtcta
    23341 gaaagggctt cgcaggctaa aataatgata atgattgaaa atgaccacga atagcggtgc
    23401 aaaaacatat tgggtccatg catgccctgc caaaataaat ctaagggctg aagataaaag
    23461 ctagccatga tgagtcctaa aagcagccca tagcccagtc ttaagcgcca gctaatagat
    23521 tttaaggtga aaaagacgat acttaacaat gaaggcaaca gaccaataaa tatcatggga
    23581 atcgcattaa actttgtcgt atcataggca ccaagtgata gctttgctaa taaatcaaag
    23641 gctcctatag gcttaatgat aatctgattg attggagaga gtgtttcacc gtaggctgtt
    23701 aggtctagat aggccggtat gagtataaaa gcacttgtta aggctgataa gattgacact
    23761 gatgtaaagc ttaaacaggc tcttaaccgt cttttccatg tgtctagtga tataaggttg
    23821 actagaaata ataaaaaaat aaagatagca accatatatc caaaataata atgctggata
    23881 aagagaagac taagtgagct ataataaagc aagggcttgg tttgagtaat cagccgatag
    23941 agccccagta agacaattgg tagaagaata aaaacatcta accagttgtt aagctctagc
    24001 tggcttgtca gaaagctcat tagggagtaa gagactgata atgtcaggac taaaaagggt
    24061 ttgattttag ggtaaatacg atgaaaggag aaataagcgg caagcccgat caaaccaaat
    24121 ttaataagtg tcaagagata gatagcatct ggcatggatt gcagattaaa aaaatagaca
    24181 agaggagaca aaaggctgcc tagataatag ctagccagag caaaaaagtt tacacctagg
    24241 ccactggtaa aggtgtaaaa aatactatca gccccatgaa gaatatttct tagggcttgc
    24301 gcaaaaataa catattgatg aaagccatca ctagctaaaa tggttttctc actgccatat
    24361 gaaattccca ttgacaaaag aacaaaaaac attatcaaaa agggaaggag gaagctagca
    24421 atgtcataaa caagagacca tgctttaggt tttgtcataa ataagccctt ctatgatatt
    24481 tttgaaaaaa gagctagaaa tagtttccag ccctcagatg tcatcggtga tcatctctat
    24541 actttaatga tgatattgag caaagctcct tgtttcttcc ttatttccaa agctctgcta
    24601 ccttagcttg aacgtctttg ttttcaagga attcatcata ggtttcgtca atacggtcaa
    24661 tcacaccatt tttagaaata acaacaatgt gattagcaat ggtttggata aactcgtggt
    24721 cgtgactggt aaaaataaca gactctttaa aatctttaat cccgtcattg agacttgaaa
    24781 tagattccaa atctaggtga ttggttgggt catcaagaag gagaacattt gattttaaaa
    24841 gcattaactt tgatagcatc acgcgcacct tctcaccacc agagagaacg ttaacggatt
    24901 ttttaacctc atctccagaa aagagcatac gtcctaagaa accacgcaag aaggtatcat
    24961 catcttcacc ctttgctgca aattggcgga gccattcaag gatagactca tcgctagcaa
    25021 agtcacgtga gttgtccttt ggcagatagg agcgactagt tgttactccc catttgatag
    25081 tcccttcata gtcaatgtca tcagccagag cgcgcataag agctgttgtt tgaatgtcat
    25141 tttgtccgat aatggcagtc ttatcacctg gccttagaat gaagctaatg ttatctagaa
    25201 ttttgtcacc atcaacggtt acagacaaat tttcaactgt tacaaagtca ttgcccattt
    25261 cacgctcagc tttaaaattg atgaatgggt atttacggct agatggaata atctcttcta
    25321 gctcaatttt gtccagcatt ttcttacgag aggttgcttg ctttgattta gaagcattgg
    25381 cagaaaagcg tgctacaaat tcttgcagct ctttgatttt ttcttcggcc ttagcattac
    25441 gatctgcctg aaggcgtgca gctaattcag atgattgctt ccagaaatcg tagttaccga
    25501 caaaaagctt aatctttcca aaatcaaggt cggccatgtg agtacatacc ttgttcaaaa
    25561 agtgacggtc atgtgacacc acaataacag tattttcaaa gtcaatcaag aagtcttcta
    25621 accatgaaat agactgaata tcaagaccgt tggttggctc gtctagcagc aaaacatcag
    25681 gcttgccaaa aagtgcttta gctaggagaa ccttcacctt atcaccattg gtgagctcgc
    25741 tcatgctttg ataatgcaat tcctcaggga tatttaggtt ttgtagtaat tgagaggcct
    25801 cactttcagc ctcccagccg cctagctcag caaagcttcc ttctaattcg gcagcgcgaa
    25861 caccatcttc ctcagaaaaa tcaggcttca tgtaaatagc atccttttcc ttcatgatac
    25921 tgtaaagctg ttcatttccc atgataacca catcaatggc acgttcctct tcgtaatcaa
    25981 aatgattttg gcgaaggaca gaaagacgct catctggtcc taaagagata tgacctgttg
    26041 ttggttcgat atcacctgcg agaattttta ggaaggttga ttttccggca ccattggcac
    26101 caattaagcc ataagtgttg ccagctgtaa atttgatatt aacatcgtca aaaagttttc
    26161 gatcactaaa gcgcagtgat acgtcagaaa ctgttagcaa tttgtcacct cattttattt
    26221 atctaatcct cattgtacct aaaaaagccc cttttttcaa tcagaaaagg gcttagggct
    26281 tacataggca gcagcacatc tttgtcctct agtttgtaat gcttggttaa gctgaagcca
    26341 cgtcccatga cctgtgctgc tggcatgaca acgataaagg cagtgtcatc gatttctaga
    26401 attttttcct gtaaagctgg caactcatag ccagaaacaa tggccattag catgatcttg
    26461 tctgatgttg tgtagcctcc tcggatagga atcttagaga caccacgatc cataacacct
    26521 gtaatataag ccttgatggc ctgatattcc tttgaaataa tcatgacatt cttagaagag
    26581 tcaaagccat tttccatgac actaatgaca tagccaataa cgagcagtcc gatcgtagaa
    26641 tacatgacat catcagcaga taaagcgatg aatcccatta aaacactaat gccatccaca
    26701 atagtcatag caactcccaa tgataatgga gaatatttgt gtaggatttg tgtcagaata
    26761 ccagtacctc cggttgatga atttccccaa aagaccattc caaggccgat cccacaaatg
    26821 atgccaccaa aaatagctgc taataattgg ttatgagtga gtgttggaag ctggctggtt
    26881 aggcgtatag caatagggta aatccatgaa ccgtagaggg ttttgatgag attttgttta
    26941 ccaagaaaga agtagcataa aatcaataaa gggatattgc ttagcattaa aaagagcgag
    27001 gggctaattc caaacagcgc tttgataaca actgaaatcc ccaccatacc acctgaagca
    27061 atattattat caacaaacat tgtgttaaag ccgatagctg tgatgaagga accaatggtt
    27121 acaaatagta aatccattac cctttttttc atatttaata cctcctttat cgtttagtaa
    27181 acataataga cccattatct cctaaaagaa tagaaaccgt caagccctat tgcttaaaaa
    27241 tcttagcagc ttgacaaatc acttaaaatg tcatagaatg accctaaact agatgagtaa
    27301 tctttccctt gtttttagag agctagtggt tggtgagagc tagcagcaag caagatgaaa
    27361 tgggctagtg gatcttttga gaggaaacca taactttcag gcctggcacc ccttatcgtg
    27421 caatttcttg agttgagaag atgagatagt attgattgat cagagatact aattgaggtg
    27481 gtaccgcgta tttattgtaa tgacgccctc acgcaagcct tttgcgtgag ggtttttgat
    27541 gtcataaaat cagtattaag gagaaatcat gacaaaacca gttattttaa caggagatag
    27601 accaacagga aagctacact tgggacatta cgtcggcagt cttaaaaatc gtgtaagcct
    27661 gcaaaatgaa aacaagtaca agatgtttgt ctttttggca gatcagcagg ccttgacgga
    27721 tcacgccaaa gaatctgaga tgattcgtga gtctattttc aatgtcgcat tggattatct
    27781 ttctgtcggc ttggatccaa gtaagtcaac tatttttatc caaagtcagg ttcctgaact
    27841 tgcagagtta acaatgtact atatgaattt ggtgtctctt gctcgcttgg agcgtaatcc
    27901 aaccgttaaa actgaaattg ctcaaaaggg ctttggtgag agtattccag caggcttttt
    27961 ggtttaccca atttctcaag ctgctgatat cacagccttc aaagctaatg tagttcctgt
    28021 tggtaatgat caaaggccaa tgattgagca gacacgtgaa attgtaagaa gctttaatca
    28081 tacctataag acagcctgct tgattgagcc agaaggtctt tacccagaaa atgaaaaggc
    28141 aggacgtcta ccagggcttg atggcaatgc taaaatgtcc aaatcactgg gtaacggcat
    28201 ctatctttct gatgatgctg acactgttcg tcaaaaagtc atgagtatgt ataccgatcc
    28261 aaatcatatt cggattgagg atccgggaca gctagaaggt aatatggtct ttcattacct
    28321 agatattttt ggccaaaaag aggacaaagc tgatattgaa gcgatgaaag agcattacca
    28381 aagaggtggc cttggagatg ttaaaaccaa gcgttatctg ctggatattt tggaaagaga
    28441 gcttgcgcca attcgccaac gccgattgga atacgccaag gataagggcg aggtctttcg
    28501 tatgctagaa gcaggaagtc aaaaagcaca ggcagtggct gcccaaacat tgtctgaagt
    28561 aaaggttgct atggggattc gttattttta atagcgtaga ggctgagaat gattcttggc
    28621 ctcttatctt ttcaaatgca cctatcactc atgagtcaaa acctgtcttt ttaatttaca
    28681 gaaatatata gaattatgtt attgacaaat gaatttagcg tgatatgata gtaacaataa
    28741 aaataggctg gggtaatatt ccctaaaaaa gaagaaaaga ggattgtgtt aatgtcaaat
    28801 tgggacacta aatttttgaa aaaaggctac acgtttgatg atgttttgct tattccggca
    28861 gaaagtcatg ttcttccaaa tgaagtcaat ttaaaaacca agcttgctaa aaatttgaca
    28921 ttaaatattc ctattattac cgcagccatg gacactgtaa cagacagtaa aatggctatt
    28981 gcgattgcgc gtgcaggtgg tcttggtgtt attcataaaa acatgtcaat tgctgagcag
    29041 gctgaggagg tgcgtaaggt caagcgctct gaaaatggtg tcatcattga tccgtttttc
    29101 ctaacgcctg agcacaaggt agctgaggct gaggaattaa tgcagcgcta ccgtattagt
    29161 ggtgttccga ttgtagagac cttagctaac cgcaaattag tcgggattat tactaatcgt
    29221 gacatgcgtt ttatttctga ttacaacgcc ccgatctcag aacatatgac aagtgagcag
    29281 ctggtgacag ctgaggttgg gactgacctt gagacagcag agcgtatcct tcatgagcat
    29341 cggattgaaa agctaccatt ggtagatgat aatggccgtc tttcaggttt gattacaatc
    29401 aaggatattg aaaaggttat tgagtttcca catgctgcaa aggacgagtt tgggcggttg
    29461 ctggtagcgg ctgcggttgg tgttacatca gatacctttg agcgtgcaga ggctttattt
    29521 gaagctggtg cagatgctat tgttattgat acagctcatg gacattccgc aggtgttctt
    29581 agaaaaattg cggagattcg cgcccacttc cctgataaaa ccttgattgc aggaaatatt
    29641 gctactgctg aaggcgcgcg tgccctttat gacgcagggg ttgatgtggt taaggttggt
    29701 atcggaccag gctcaatttg tacaactcgt gtcattgctg gtgttggggt acctcaagtt
    29761 acagctattt atgacgcagc tgctgttgct cgtgaatatg gcaaaaccat tattgctgat
    29821 ggtggtatta agtattcagg agacattgta aaagcccttg cagcaggcgg caatgctgtc
    29881 atgttaggct ctatgtttgc tgggacagat gaagctccag gtgagactga aatttaccaa
    29941 ggacgcaagt ttaaaactta tcgtggcatg ggatcaattg cagctatgaa aaaaggatca
    30001 agcgaccgtt acttccaagg ctctgttaat gaagccaaca agctagtgcc agaaggtatt
    30061 gaaggacgtg ttgcttataa gggagctgcc tctgatattg tctttcaaat gcttggtggt
    30121 attcgctcag gtatgggata tgttggagct ggtactatcc gagaattgca tgacaatgct
    30181 caatttgtag agatgtcagg agctggtctg attgaaagtc acccacatga tgtccaaatc
    30241 acaaatgaag caccaaatta ttccatgcat taatcctgca ggtgtttact tgatgtagta
    30301 tttgacatat ctattttaaa agctgagata ttttctcggc tttttttgtt gcacgattaa
    30361 accatgatta gaaatgacag cttgctagcc ctagctattt gctttttagc tttgtgatat
    30421 ttcaatgcta ggctaatgat caaatcatac tgaatgctct taagcgtaat accttccaaa
    30481 aatggcataa ccctaaaagg attaacttaa atagacatg
//
LOCUS       DARYXW010000014        29856 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.014, whole genome shotgun sequence.
ACCESSION   DARYXW010000014 DARYXW010000000
VERSION     DARYXW010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29856)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29856)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29856
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.014"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(<1..105)
                     /locus_tag="TV191_000523"
     CDS             complement(<1..105)
                     /locus_tag="TV191_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL1507062.1"
                     /translation="MHQNPTERSVLLSTYEALQLMLAFGSFLLTLISLV"
     gene            complement(489..1733)
                     /locus_tag="TV191_000524"
     CDS             complement(489..1733)
                     /locus_tag="TV191_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1507063.1"
                     /translation="MRNKKTSIRLVQKYGICSAVVALATIASLGIGNDVRAEDFTYPS
                     MYNQGYFFQQFIKKEILNPGSGSSSDWETSTHYNNGRMLENVLRYLWRVEQFLKKSTG
                     QSEQLYKLYEKDSLGIPGPQGPMGPAGPQGLRGERGPVGERGPIGPQGPEGKPGQQGP
                     KGDTGPQGEPGQQGPKGDIGPQGEPGLPGPKGDTGPQGAPGQQGPKGDTGPQGEQGLQ
                     GPKGDTGPQGAPGQQGPKGDTGPQGEPGQPGPKGDTGPQGEQGLQGPKGDTGPQGAPG
                     QQGPKGDTGPQGAPGQQGPKGDTGPQGVPGQQGESQKVPEVPKAPETPEKKEQPQAPK
                     EPETPKAPEQSPAPQAPKSSEQPASPKAPAPQSAPNKSAAPAAQKGTLPATGEANHPF
                     FTLAALSVIASAGVLGLKKKQD"
     gene            complement(2163..3305)
                     /gene="tgt"
                     /locus_tag="TV191_000525"
     CDS             complement(2163..3305)
                     /gene="tgt"
                     /locus_tag="TV191_000525"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEL1507064.1"
                     /translation="MTNYPITYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEIGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQAILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAADLVSMDFPGYSI
                     GGLAVGESHAEMNAVLDFTTPLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSEGRLVVKNAKFAEDFTPLDHHCDCYTCQHYTRAYLRHLLKADETFGMR
                     LTSYHNLYFLVNLMKQVRQAILDDNLLEFRQDFLERYGYNSSSRNF"
     gene            3710..4555
                     /locus_tag="TV191_000526"
     CDS             3710..4555
                     /locus_tag="TV191_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEL1507065.1"
                     /translation="MSIREIKREARQTLKGLKGKYLLFLVPIILSIFYSGIEVHQTYV
                     TTQGIEVSVGASYFPLIVLIMLTVFTLSAAYTMLDVIRYYRREVSFSEATIAFSGNLF
                     GKVLVLLIIKGLLFILWSLIWIVGLVILTISSAALLTSYNTGAAVMTPIIFMVIGFVI
                     FIIGLIVYMNRYCAYSMAEYILYDKVKEGTYMGAITAIEESKDMISGYKGKYFLLHLS
                     FIGWFILVILSFGLIYIYVLPYYTTADVTFYHHLKHIHDETELPIDAERLTITGSKEA
                     PSAIS"
     gene            complement(4751..8713)
                     /locus_tag="TV191_000527"
     CDS             complement(4751..8713)
                     /locus_tag="TV191_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NPCBM/NEW2 domain-containing protein"
                     /protein_id="HEL1507066.1"
                     /translation="MFKPYTDGKQRFAIKTFKTGAASVLVATLFLTLGLTTVSADEQQ
                     VTASAAIATTLEAQEAVDQQAADQSATAAQDTAAEGSSETLPVVIGTATTETTDSKSQ
                     VAAAEQATEASAEETTKQEQTEVSQAVETTNKTEAKDYIYLSDETRVNPSKVGHGSFL
                     QDKNPAGGTITLVVDGEVLAFDKGIAVHAPSQLYYDVEQYSNEYTRLSAYLGVDYSRR
                     GKDDGVSFNIYKSKDGKSWESLVTTGTVTGTSEAVYVDLDITGAKYVKLIANSLKNNG
                     NDHSVYADLRLLKTDYDLSSEVSYDRLKTTEEYDALLSKNSVTDNYDNPDNLALVLER
                     EFVNRVGYHTIQSAVKKNEKVKVALDWLLSDEDALSLFLEAGSMFNGSTLKTLNALGD
                     LYATNKADLEDKGNGYVYKKMMLATAVAYCKEIKSFVVNYGGTYLASDPVLKYQAFKE
                     LYRDNEFLRKEEFANYNMELVRAVMDAKIDDEEILWLHHYAEQKYGDKVASYTSGYSY
                     TKYKNIGYGGADMRSADNQAQWTEKYQLVGTLNDDAFNVTYDNRHRIWMLMEKGAVCW
                     GLSNLGVAVNEVFGIPAVNIYQNDHEAYLVYRQDDQGNGIWDIRDNVYGNRWAISYSR
                     WGTTTATEARLLLGWGLKSYNDIHKNASYMLLAQAALNQYDKFKESLYYNLIANVYEA
                     GSDQQIEAYSKALDVLELNLDTYDGLIEAYAKNGQKTDQDWLDLGKRVIAAYTYYPQV
                     MVEAIKRITPNISDQAAKAELDLLSYNALIAAKTATDKEVLQSNEVRIIANYILTGNP
                     IETASFSFDDKTLRLHENYQDTDLTVRYSIDNGKTWLETKDKVIVFSDDLLAKLNIED
                     GILVGFDAVSATYRINLTKAAAPTNSSLYGNDLENRLIGAIEHLEVSLDNGQSWQAYD
                     GTERFNDTVTVLARYRAHGTSLASDSVTYTFTADSTDPTMHYISIDDIQAVTYANEQS
                     GRSGKHMVDGRDMATQWHTLFNQVTEDKSYTVEFKDDKNFSAIAYLPGGVNGMIHSAK
                     VDISSDGKVWTTVVDSTDWKQNTELKTVSFTPTTGRFVRITALDTYGKSSGQANKFVS
                     GSAYRFFEDISSPIEAPVRNDILALKDSILTILKETNTATKEIESFAITNSGLTAATT
                     EKNQAIQGKILETIKDLGLTGTYYITLENTGTYDDLADLLNHQLVITYQDKAAGPLYV
                     LAMNSLSSGDEALDAEYSLDLIKSALKSALESENIDLKTFEGLSISSQLPAAKTAVNT
                     ALMEKLQQLLPGDYFIDLAGLPTAASIDELLDSQLFIYYRESHWTTAYALDRGAFQQL
                     "
     gene            complement(8848..10692)
                     /locus_tag="TV191_000528"
     CDS             complement(8848..10692)
                     /locus_tag="TV191_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HEL1507067.1"
                     /translation="MKKFTKRCLKGCGLVGLVFSTGLVALSDNIDSALTVGAETTTAS
                     AFENNGTGQHLNWHIDIPQEYTVELGEPITISDLMSQITVTRKGSNGTVNDGDTFDFI
                     SNGDGSRGIDTPGVKIWFDFYNAAGTSFLTDEMLASPTYAVPGGSYTIKAWVFYGKND
                     TKKLFTFKLKNSNSNKTELRKSLEEAKLKLSQPEGTYSDESLQALQSAVTIGKTYLNS
                     DPDQNTVDQSVTTIDSAITSLVNLNALNEAINQATPFITDGKEYPKEAYDGLVQKLAA
                     AAKLQNSFGPSQGDVDKAATDLTQALTTLKTAVAHEALDQALAKLLELYRENPNLALT
                     SESLKELYNKAIEAAGTFYRTVNKDKERKDISLYELERYTTETNSVVDTILKVKAAIA
                     EEGKAKLRSALDQLNALIGENLDLSPYTAASAQAYTDQLAKAKEVAAAGETAYAQETE
                     PTAITNSLVKVLNAKKSLSDAKAALVAKPVDPVDPVDPVDPVDPVDPVDPVDPVDPVD
                     PVDPVDPVDPVDPVDPVDPVDPVDPVDPVDPIDPADPVKPSDPEVKPEPKPESKPEAK
                     KEDKKAADKQQVLPATADTANPFFTAAALAVIACAGQLAIVSRRKESN"
     gene            complement(11052..11525)
                     /gene="perR"
                     /locus_tag="TV191_000529"
     CDS             complement(11052..11525)
                     /gene="perR"
                     /locus_tag="TV191_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide-responsive transcriptional repressor
                     PerR"
                     /protein_id="HEL1507068.1"
                     /translation="MDIHSHQQALNAYENVLEHLRDKHIRITETRKAIISYMIQSTEH
                     PSADKIYRDLQPQYPNMSLATVYNNLKVLVDEGFVSELKISNDLTTYYDFMGHQHVNV
                     VCEVCGTIADFMDVDVMDIAKEAHQQTGYKVTRIPVIAYGVCPSCQTKQGKDTDY"
     gene            complement(11562..12014)
                     /locus_tag="TV191_000530"
     CDS             complement(11562..12014)
                     /locus_tag="TV191_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEL1507069.1"
                     /translation="MIDTFQNPSDETITSYLESSKTIAVVGLSDRQTTAAYDVARFMQ
                     AKGYRIVPVNPRLAGQSVLGEVVYASLAAIPFKVDIANVFRRSEYLPQVAQDFLACQG
                     QVFWAQLGLYSQEAEELLRSAGKADIVMNRCIKIDYLRLISKQDQDSC"
     gene            complement(12254..14896)
                     /gene="polA"
                     /locus_tag="TV191_000531"
     CDS             complement(12254..14896)
                     /gene="polA"
                     /locus_tag="TV191_000531"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEL1507070.1"
                     /translation="MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGF
                     HLMLDHMMKRVQPTHVLVAFDAGKTTFRTELFADYKAGRAKTPDEFREQFPYIRDMLG
                     ALGIAFYELEHYEADDIIGTLDKMAERTEIPFDVTIVSGDKDLIQLTDANTVVEISKK
                     GVAEFEEFTPAYLMDKMGLTPEQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEYGS
                     LEGIYEHIDSFKPSKMKENLLHDKEQAFLSKTLATINTSAPITIGLEDIVYQGPDLDR
                     LSQFYDEMDFVQLKNALASQLPQEPVAEIAYQEVTDIRADMFSDDTVFYFEALRDNYH
                     REELIGFAWGNQGQIYASADISLLTTKLFKKVLEQPIATYDFKRSKVLLSHLGLDLPA
                     ASYDARLANYLLSTVEDNEMATLARLYTTISLDTDEVVYGKGVKRAVPDKAVLLGHLA
                     RKVQVLLDSRPVMLDKLAEHEQADLYTDIELPLANVLAKMEIEGIAVNQDSLQEMAEQ
                     NKVVIEELTQEIYEMAGEVFNINSPKQLGVILFEKMQLPLHLTKKTKTGYSTAVDVLE
                     RLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIMADGRIHTRYLQDLTQTGRLSSVDP
                     NLQNIPIRLEQGRLIRKAFTPSHDDAVLLSSDYSQIELRVLAHISGDEHLIAAFKEGA
                     DIHTSTAMRVFGIEKPEDVTANDRRNAKAVNFGIVYGISDFGLSNNLGIPRKQAKAYI
                     DTYFERYPGIKAYMERVVREAKDKGYVETLFKRRRQLPDINSRQFNVRSFAERTAINS
                     PIQGSAADILKIAMINLDQALVAGGFETKMLLQVHDEIVLEVPNHELAAVKALVKETM
                     ESAVSLAVPLRVDESAGKSWYEAK"
     gene            complement(15320..17050)
                     /locus_tag="TV191_000532"
     CDS             complement(15320..17050)
                     /locus_tag="TV191_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HEL1507071.1"
                     /translation="MENLLQTTLPVAQLVEQLTEWLTKTFSGFFDLLQLVGNALMDWI
                     TQTLLFINPLLFMLLVTCAMFFLARKKWPLPIFTLLGLLFVYNQGLWAELINTFTLVL
                     VASLISVLLGIPLGIWMAKNKIVHQVINPMLDLMQTMPAFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLALRHIPTELVEASDAFGSTPKQKLLKVELPLAKHTMMAGVN
                     QTMMLALSMVVTGSMIGAPGLGREVLSALQHADIGRGFVSGLALVILAIILDRMTQHF
                     NGKPQERTQTGKTKKWLGLAALAVFLLSALGRGFAAMLSSSADKGQKVTIAYVQWDSE
                     VASTHVIAQVLRDEGYQVTLTPLDNAVMWQTIANGDADFSTSAWLPVTHQQQYQKYQD
                     KLDNLGPNLKGTKLGLAVPAYMSDVNSIEELSDQANQQIIGIEPGAGIMTAADKTQKA
                     YSNLADWELVAASTGAMTTSLDQAVKKKEPIVVTAWSPHWMFAKYDLKYLADPKKTFG
                     SKENINTIARRGLKADLPAVHRIVDHFHWEKEDMEAVMLDINQGMTPEAAAKKWVASH
                     ADKVAKWTQS"
     gene            complement(17068..18264)
                     /locus_tag="TV191_000533"
     CDS             complement(17068..18264)
                     /locus_tag="TV191_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HEL1507072.1"
                     /translation="MGTILEVRHLSKLFGKKQKAALEMIKAGKSKSAIFKKTGVTVGV
                     YDASFEVQEGEIFVIMGLSGSGKSTLVRMLNRLIEPSAGSILLEGRDISKLSVDQLRE
                     VRRHDMNMVFQSFALFPHKTILENTEFGLELRGVPKQERREIAKRALDQSGLLEVRDQ
                     YPDQLSGGMQQRVGLARALANSPKILLMDEAFSALDPLIRRDMQDELLELQETMKQTI
                     IFISHDLNEALRIGDRIALMKDGQIMQIGTGEDILTNPANDFVREFVEDVDRSKVLTA
                     QHIMIKPITTTVDLDGPQVALNRMHNEEVSMLMATNRRRQLIGSLTADGAIEARQKKL
                     PLSEVIDRNVRTVSKDTVITDILPLIYDSSAPIAVTDEQHRLLGVIIRGRVLEALANI
                     PDDDLN"
     gene            complement(18463..18717)
                     /locus_tag="TV191_000534"
     CDS             complement(18463..18717)
                     /locus_tag="TV191_000534"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507073.1"
                     /translation="MLLDMTSSYGQSKLTLCLADLIAIGSLLGSLSIGLVAGQESDRS
                     IKSARGGCWVSSQGAKCQKGLLAVVCSGLLSAWLTSDITA"
     gene            complement(18770..19861)
                     /gene="ulaG"
                     /locus_tag="TV191_000535"
     CDS             complement(18770..19861)
                     /gene="ulaG"
                     /locus_tag="TV191_000535"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEL1507074.1"
                     /translation="MAKVQDITRESWILSTFPEWGTWLNEEIEEEVVPEGNFSMWWLG
                     NCGIWIKTPGGANVVMDLWSNRGKATKKVKDMVRGHQMANMAGVRKLQPNLRAQPMVI
                     DPFMINELDYYLVSHYHSDHIDINTAAAIINNPKLDHVKFVGPYECGKIWESWGVPKD
                     RIIVVKPGDSFAFKDIKVTAVESFDRTCIVTLPVAGAEENGGELAGLPVTDEELARKT
                     VNYIFETPGGTIYHGADSHFSNYFAKHGRDYDIDVVLNNYGENPIGIQDKMTSVDLLR
                     MAENLRAKVVIPVHYDIWSNFMASTDEILELWKMRKERLQYQFHPFIWEVGGKYTYPQ
                     DQDRIEYHHPRGFDDCFLEDSNIQFKALL"
     gene            complement(20056..21702)
                     /locus_tag="TV191_000536"
     CDS             complement(20056..21702)
                     /locus_tag="TV191_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEL1507075.1"
                     /translation="MIILDKKSYDLLSYLIRLKEAETVMAISAALGQSRRKIYYHLDK
                     INEALPSHVAQIVSYPRVGILLNSEQKAACQQLLNEVADYHYVMKGDERRSLSAIYIA
                     VATERVTLDKLMMINDVSRNTILNDLAELREELSSYNNKIQLHATKAKGYYFDCHPMA
                     LIQYLYKVLAGVYQGGNSSFIELFDHKLSETQGLSAYFSKEVLDYFHEYLFLSQASLG
                     KTINIQDSQFMLQILPFILLSYRNMQLHSETKTALKRDFNLIWKRKEYQIAKALASEL
                     YHNFKLHLDDIEVGMIAMLMLSFRKDQDHHVESQDYEQMRATIGDFIDQLELRYQLHF
                     THKKDLLRQLTRHCKALVYRKAYGIFSINPLTDHIKEKYEELFAMAQSCAVILEQAWQ
                     IRLTDDDVAYLTIHLGGELRHSHADWDKTKLVIVSDDGIGIQKLLLKQCQRYLPNCQI
                     EAVFTTEQYQSVFDLMSVDIVVSTTDALEALVPVLIVNPILSDDDIIRLIRFSKQGRL
                     SDSSRFSLELEKAIETIVKDDADRYALKTKIEKLIHHELL"
     gene            complement(22006..22722)
                     /locus_tag="TV191_000537"
     CDS             complement(22006..22722)
                     /locus_tag="TV191_000537"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEL1507076.1"
                     /translation="MAKRLQEMRERVCAANKALPLHGLVKFTWGNVSEVCRELGRIVI
                     KPSGVDYDQLTPENMVVTDLDGTIVEGELNPSSDLPTHVQLYKAWPEVGGIVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGPIPCARSLTADEVNGAYEKETGTVILEEFASRGL
                     DPMAVPGIVVRNHGPFTWGKTPELAVYHSVVLEEVAKMNRLTEQINPRVEPAPTYIMD
                     KHYLRKHGPNAYYGQKGSRH"
     gene            complement(22722..23585)
                     /locus_tag="TV191_000538"
     CDS             complement(22722..23585)
                     /locus_tag="TV191_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003100317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEL1507077.1"
                     /translation="MARPIGIYEKATPKHFTWLERLQFAKVLGFDFVEMSVDESDARL
                     ARLDWSKQERLDIVKAIYETGVRIPSICFSGHRRYPLGSSNPETEATSLELMKKCIVL
                     AQDLGVRTIQLAGYDVYYEEKSPETRARFIKNLRQACTWAEEAQVILAIEIMDDPFIN
                     SIEKYLAVEKEIDSPYLFVYPDTGNVSAWHNDLWSEFYNGHRSIAALHLKDTYAVTET
                     SKGQFRDVPFGQGCVDWEAMFDVLKKTHYHGPFLIEMWSENCETVEETRAAIKEAQDF
                     LYPLIEKAGLS"
     gene            complement(23590..24255)
                     /locus_tag="TV191_000539"
     CDS             complement(23590..24255)
                     /locus_tag="TV191_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEL1507078.1"
                     /translation="MMTHIPKLQVALDHSDLQGAVRAAVAVGHEVDVIEAGTVCLLQV
                     GSELVEVLRSLFPEKIIVADTKCADAGGTVAKNNAKRGADWMTCICCATIPTMAAALK
                     AIKEERGERGEIQVELYGDWTYEQAQLWLDAGISQAIYHQSRDALLAGEVWGEKDLNK
                     VKALIDMGFRVSVTGGLDINTLKLFEGVNVFTFIAGRGITEAEDPAAAARAFKDEIRR
                     IWG"
     gene            complement(24350..24835)
                     /locus_tag="TV191_000540"
     CDS             complement(24350..24835)
                     /locus_tag="TV191_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEL1507079.1"
                     /translation="MNLKKAFIENNSIRLGLSAASWQEAVKLAVQPLIDSGAVTSEYY
                     DAIIASTEKYGPYYVLMPGMAMPHAEAGVGVKRNAFALITLTKPVTFSDGKEASVLLT
                     LAATDPSIHTTVAIPQIVALFELEDAISRLVACHTPAEVLALVDESKNSPYLEGLDLD
                     S"
     gene            complement(25051..25329)
                     /locus_tag="TV191_000541"
     CDS             complement(25051..25329)
                     /locus_tag="TV191_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1507080.1"
                     /translation="MVKVLTACGNGMGSSMVIKMKVENALRQLGVTDIQSASCSVGEA
                     KGLASGYDIVVASNHLIHELDGRTKGHLVGLDNLMDDNEIKTKLQAVL"
     gene            complement(25444..26877)
                     /locus_tag="TV191_000542"
     CDS             complement(25444..26877)
                     /locus_tag="TV191_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL1507081.1"
                     /translation="MKMLIAPLNWFSQDILQNPAFFVGLLVLIGYLLLKKPLHEVFAG
                     FVKATVGYLILNVGAGGLVNTFRPILVALGKKFELKAAVIDPYFGLAAANTKLEEMGS
                     ISVATTALLIGFGVNILLVALRKVTKVRTLFITGHIMVQQAATISVFVLLLIPQLQNA
                     FGAWAVGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAPFFGKKE
                     ENLDNLKLASFLTIFHDTVVASATLMLVFFGAILAVLGPDMMSNAELIGAGAFNPAKQ
                     AFFMYILQTSLTFSVYLFILMQGVRMFVSELTNAFQGISSKLLPGSFPAVDVAASYGF
                     GSSNAVLSGFTFGLIGQLITIALLVIFKNPILIITGFVPVFFDNAAIAVYADKRGGWK
                     AAVALSFISGILQVALGAVAVGLLGLTGGYHGNIDLVLPWLPFGYLFKFLGIAGYVVV
                     CVFLLAIPQLQFARAKDKEAYYRGEAQ"
     gene            complement(27360..27980)
                     /locus_tag="TV191_000543"
                     /pseudo
     CDS             complement(27360..27980)
                     /locus_tag="TV191_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003104274.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(27982..28599)
                     /locus_tag="TV191_000544"
     CDS             complement(27982..28599)
                     /locus_tag="TV191_000544"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507082.1"
                     /translation="MKLSNLLVVGMKACLTGLLIHLLLIKANMTGERDFHNLVCYRLL
                     MPFPVIEGETADFVKVITLLGLSFNSFYFTISFLADLAEGTKEIFRFHARSQLVFFNK
                     LWRTSTIFYIKEWLLFIVLILGVLMTYYGAPYHIERLCYLMVSWLTIDICLIYVMIRY
                     ASSAVVAMILFASLTLIRYFLFDVWWCLLLIVLVHMLYDNYYKES"
     gene            complement(28586..29290)
                     /locus_tag="TV191_000545"
     CDS             complement(28586..29290)
                     /locus_tag="TV191_000545"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507083.1"
                     /translation="MKHILFFDTSAVDLSGGIEVKKSLLLSMIRLDSVVFDFSFYQSF
                     IYPLVMILVAYAYYYLKSRHLKYLIGRKSDYGKRCIFLKLQLSLYVLLSFYIVIFALT
                     LVSWLNGVAHMNGNLMPYFDQNSILRFFGQGATTFIAYYCLVKSLALFVHTYFVCFLV
                     DYLQSFIKSSMLYLILMWALSPLLYSYLPPKYVLMTSLMSTSYSDADIPYLLSPYLGL
                     VGVCIVLKLRKHHEII"
     gene            complement(29445..29846)
                     /locus_tag="TV191_000546"
     CDS             complement(29445..29846)
                     /locus_tag="TV191_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507084.1"
                     /translation="MKLGKIKIGLLAIVASTLLISSLVIAERQIGYLQNFRITSSFGR
                     TKDYLVKSAAPYYVVNLDSRGRNREIVVRHYLANSNGQRRSDIDKTWTGDRGIYTQDT
                     KSGYLYALHLVRENWWDGATTISGSWSPDNW"
BASE COUNT         8512 a         7006 c         5845 g         8493 t
ORIGIN      
        1 gactaagctg attaaggtaa gtaagaaact accaaaagcc agcatgagtt gaagggcctc
       61 gtaagtagac aataaaacgc tcctttctgt tggattttga tgcattgccc ataggtatca
      121 ccacctttca gaaatcagag ccaccgcctt agcttttctg taaagaacat tattatatca
      181 taatcacaca agaatccgtc aaatcttaaa ctaatcaggc ggctttttta tgctctgact
      241 ataggtctga agagaagatg ctagatgtct taggtggctt tccatttaaa ctacgaggtc
      301 ttctttctca cagagtatag ccccctcttt tttcagctac tgtttcggag gcaagctggc
      361 atttcgtcta aattgctttt gtttttccct gagcattcga aaaaatcctt tatttctacc
      421 tgacatatca ctaaaagagg gtcctgtgac cctcttttat agctatctgt tagagagata
      481 tgcaattgtt agtcttgttt tttcttcaag cctaggacac ctgcgctagc aatgacgctg
      541 agagctgcaa gggtgaaaaa tgggtgattt gcctcccccg tagctggtag cgtgcccttt
      601 tgagctgctg gagccgctga tttgtttggt gctgactgag gagctggtgc ctttggacta
      661 gctggctgct ctgaagattt tggtgcctgt ggagcagggg attgctccgg tgcctttgga
      721 gtctctggtt cttttggtgc ttgtggttgc tcttttttct ccggtgtttc tggagccttt
      781 ggcacttctg gcaccttttg tgattcccct tgttgacctg gcactccttg tggcccagta
      841 tcaccttttg gaccttgttg acctggtgcg ccttgtgggc cggtgtcgcc ttttggtcct
      901 tgttgacctg gtgcgccttg tgggccggta tcaccctttg gtccttgaag tccctgttcg
      961 ccttgtggcc cagtgtcgcc ttttggtcct ggttgacctg gctctccttg cgggccagta
     1021 tcaccttttg gcccttgttg acctggtgca ccttgtgggc cggtatcacc ctttggtcct
     1081 tgaagtccct gttcgccttg tggcccagta tcaccttttg gcccttgttg gcctggcgct
     1141 ccttgaggac cggtgtcgcc ttttggtcct gggagacctg gttcaccttg tgggccgatg
     1201 tcaccctttg gaccttgttg acctggctct ccttgtggcc cagtatcacc ttttggccct
     1261 tgttggcctg gttttccttc tggtccctgt gggcctattg gtccacgctc accaactggt
     1321 ccgcgttccc ctcgaaggcc ttgaggtcct gcgggaccca ttggaccttg aggtcctggt
     1381 atccctaatg aatctttctc atacaatttg tataattgct ctgattggcc tgtcgatttt
     1441 tttaaaaatt gctccactcg ccatagatat cttaaaacat tttctagcat tcgaccattg
     1501 ttataatgtg tcgaagtttc ccagtcactt gagctaccag aaccaggatt aagtatttct
     1561 ttttttatga actgttgaaa gaaatatcct tgattataca tagaaggata tgtaaagtct
     1621 tctgccctta catcatttcc aatccctaag ctagctatgg ttgctagggc gacaactgct
     1681 gagcagatac cgtacttctg aacaagcctg atacttgttt tcttgtttct catgtttatc
     1741 tccttttagt ttagaaatgt taacgatttc taatcttttt tcttccaaag aaaatcttaa
     1801 catgacgctt gcgggctgtg aatatgtttt ggggaattcg cttccgtagt ttcgtttttt
     1861 tctaatcaaa gggtcaattg tctgacgcta gtgtcttttg gcattggcct ttagcttagg
     1921 aagactgcct atgttagcaa gcttttcatt agcttatccg ttttgataaa gggtaagcga
     1981 cgaggataat ctgactttgt cttttgcttt tgttagattt tttaatgttt ttttgatgtc
     2041 tgatgacttt taaaaaaagc cttcttttga taggcaagct taaaaggcct aggcaaaagc
     2101 ccagaccctt gctgctatta tctgttattg tggaaagcta ccgctctttg gcactgtcat
     2161 gcttaaaaat tgcgacttga gctattgtaa ccatagcgct caaggaaatc ctgacgaaac
     2221 tctaaaaggt tatcgtccaa gatagcttga cgcacctgct tcatgaggtt tactaagaag
     2281 tataggttat ggtaactggt caagcgcatg ccaaaggtct catcagcctt taagagatga
     2341 cgcaggtaag cacgtgtgta atgctgacag gtgtagcagt cacaatgatg gtcaagtggg
     2401 gtaaagtcct ctgcaaactt agcatttttc acaacgagac ggccctcgct ggtcatgcag
     2461 gtgccattgc gagcgatacg ggttggcagg acgcagtcaa acatgtcaac cccacgaatc
     2521 accccatcaa tcaggctatc aggtgcacct acccccatca ggtagcgtgg cttattttca
     2581 ggtaaaagtg gcgttgtaaa atcaaggaca gcattcatct cagcatggct ctcaccaact
     2641 gccaagccac cgatagaata gcccggaaaa tccatgctca caaggtccgc agcagattga
     2701 cgacgcaggt cctcaaagcc agctccctgc acgataccaa agaggccttg atcatgagga
     2761 cggcggtgag ccttcaagcc acgctctgcc caacgactgg tgcgctcaat ggattttttc
     2821 acataatcat agggctggta aaattgcggg cactcatcaa agctcatcat aatgtcagac
     2881 cctaggttat tttgaatgga gatcgctttc tctggtgata aaaacatctt tgagccattc
     2941 aggtgatttt taaaggtcac cccctcctca gtgatgtttc tggagtctgc caaggaataa
     3001 acctgaaagc cgcctgagtc tgtcagaatt gcctgatccc agttcataaa tttgtgaagg
     3061 ccgcctgcac gcgcaatcag ctcatctcct ggtcgtagcc ataggtgata ggtatttgac
     3121 aaaataatgc ctgacccaat ctccttgagc tcctcaggag actgtgtctt aaccgtcgcc
     3181 tgtgtcccta ccggcataaa catgggcgtc ggaaaggtcc catgcggggt aataatctca
     3241 ccgagacgag cacctgtatg cttttccttt ttgatcaaac gataagtaat agggtaatta
     3301 gtcattgttt cttttttcct tgctatcaag ataaacagtc ttgagcgttt tgcataccac
     3361 ttacaaagca cttagtcaag cggtatgggc ttgtttagag ccctatcatt ttatcaaaaa
     3421 atctctgact tgtcatgcct tcaaagagac aagatcccga agcaatggca cgacagacgc
     3481 atgaaggagt tttagcaaga aaagaaagct ttctgtcgtt caatgttcag ctatttcaag
     3541 tatatgtctt atcttttata aactttacta cagaaaaatc gttgaaaatg tttgctttac
     3601 tctatactat cattcagaaa tagctgtttc gcgcgtttgt cgtgagcaag gacggtatgg
     3661 gtatcactgg ctcctagaat atggtataat gtaccaaagg agttgtacga tgtcaattag
     3721 agaaataaaa cgtgaagcta gacagacttt aaagggacta aaggggaaat acctcttatt
     3781 tttagtaccg ataatcttat ctatttttta ctcaggaatt gaggttcatc agacctatgt
     3841 gaccactcag gggattgagg tatcagtcgg ggcaagctac tttcctttga ttgttctgat
     3901 aatgctgacg gtctttacct tatcagcagc ctataccatg ctagatgtta tccgctacta
     3961 tcgtcgtgag gtctcttttt cagaggcaac gatagctttt tctggaaact tgtttggcaa
     4021 ggtccttgtt ttgttgatca tcaaagggct cctatttatc ctatggtctt tgatttggat
     4081 tgttggcttg gttattctaa cgattagctc tgcggcatta ctgacaagct acaatactgg
     4141 tgctgctgtg atgactccaa tcatctttat ggttattggt tttgtgattt ttattatcgg
     4201 gcttattgtt tatatgaatc gttattgtgc ttacagcatg gctgagtaca ttctctatga
     4261 caaggtcaag gaaggcacct atatgggtgc tattacggca atcgaagaga gcaaggacat
     4321 gatctcaggc tataaaggaa agtatttttt actacacctt agctttattg gctggtttat
     4381 cctagtaatc ttgtcttttg gcttgatcta tatctacgta ctgccttatt acaccactgc
     4441 tgatgtgacc ttttaccacc atttaaagca cattcacgat gaaacagagc tgccgataga
     4501 tgctgaaagg cttactatca caggttcaaa agaagcccca tctgctatta gctagcctta
     4561 acgatatgcc tctatgtctc tcatgacctt gttcagagta gacatagagg ttttttgcat
     4621 gacctttgat aactttttta tagtaaaaaa gaggagccca tcagttgcct atccaaagct
     4681 agatgacaca tctaacggtt ggaaggcttg cttacaggcc ctcttttagc aatgttagcc
     4741 caagactatc ctaaagctgc tgaaaagctc ctcggtctaa ggcataggca gtcgtccaat
     4801 ggctctcacg atagtaaata aagagctggc tatctaatag ctcatcaatt gaggctgctg
     4861 ttggcagacc tgctaggtca atgaaataat cccctggaag aagctgttgt agcttttcca
     4921 ttaaggcggt attaacagcg gtctttgctg ctggtaattg actagagatt gataagcctt
     4981 caaaggtctt taaatctatg ttttctgact ctaaagctga ttttaaggct gatttgatca
     5041 agtctaggct gtattcagca tctaaggctt catcgcctga tgagaggcta ttcatcgcca
     5101 atacatacaa agggcctgct gccttatcct gataggtaat gacaagttga tggttcagca
     5161 aatcagctaa gtcatcataa gtaccagtgt tctcaagagt aatgtaataa gtccctgtga
     5221 gccctaagtc cttgattgtc tctaaaatct tgccttggat tgcttgattt ttttcagttg
     5281 ttgccgctgt tagaccacta tttgtaatag caaagctctc aatctctttg gtagctgtat
     5341 tggtctcttt tagaatggtt agaatactat ctttaagcgc tagaatatca tttctaaccg
     5401 gtgcttcaat agggctagag atgtcttcaa agaaacgata agcagaaccg ctgacaaatt
     5461 tattggcctg tccgctgctt tttccatagg tgtctaaggc agttattcta acaaatcgac
     5521 ctgttgttgg tgtaaagctg actgttttta gctcagtatt ttgcttccaa tcagtgctat
     5581 cgacaaccgt tgtccagacc ttaccgtctg agctgatgtc gacctttgca gaatggatca
     5641 taccattaac acctcctggg agataggcaa tagcagagaa gtttttatcg tccttaaact
     5701 caacagtata tgacttgtcc tcagtaacct gattaaataa ggtatgccat tgggtggcca
     5761 tatctctacc atctaccata tgcttgccag acctgcctga ttgctcatta gcataggtca
     5821 ccgcctgaat atcatcaatt gagatgtagt gcattgtagg atcagtgctg tctgcggtaa
     5881 aggtataggt aacgctgtca cttgctagac tggtgccatg agcccgatag cgagcaagaa
     5941 ctgtgacagt gtcattgaag cgctctgtgc catcataagc ctgccaagac tggccattat
     6001 ccagactgac ctccaaatgt tcaatagcac caatcaagcg attttccaag tcattgccat
     6061 aaaggctgct gttggtcggt gctgctgcct ttgtcaggtt aatcctgtag gtagcagata
     6121 ccgcgtcaaa gccaactaaa ataccgtcct ctatattaag cttggccaaa aggtcatcac
     6181 taaaaacgat aaccttgtcc ttggtttcaa gccatgtttt cccattatca atagaatagc
     6241 ggactgtcaa atctgtatcc tgataattct catgcaaacg aagggtcttg tcatcaaagc
     6301 taaagcttgc tgtttcgatt ggattgcccg ttaggatata gttggcgata attctaacct
     6361 cattagattg gagcacttcc ttatcagttg ctgttttggc tgcgattaga gcgttatagc
     6421 tcagtaaatc tagctcagcc ttagctgctt gatcgctgat attaggcgtg atacgcttga
     6481 tagcctctac catgacctgt ggatagtagg tgtaagctgc aatgacacgc tttcctaagt
     6541 ccagccaatc ctgatctgtt ttttggccat tttttgcata ggcctctatc aagccatcgt
     6601 aagtatctag attaagctct agtacatcta aagccttgct gtaggcctca atctgttgat
     6661 cactgccagc ctcgtagaca ttagcgatga gattataata aagcgattcc ttgaacttat
     6721 cgtattggtt taaggctgct tgcgccagca gcatatagct agcgttttta tgaatgtcat
     6781 tgtaggattt taggccccag ccaagcaaga gcctagcctc tgttgctgtt gtggttcccc
     6841 aacgagaata agagattgcc cagcgattac cataaacatt gtctctaata tcccaaatcc
     6901 cgttgccctg atcatcttga cggtaaacca aataagcctc gtggtcattt tggtaaatat
     6961 tgaccgctgg aataccaaag acctcattga ctgctacacc taaatttgat aatccccagc
     7021 aaacagcccc tttttccatc agcatccaga tccggtgacg gttgtcataa gtaacattaa
     7081 aggcatcgtc attgagggtg ccaacgagct gatatttttc tgtccattga gcttgattgt
     7141 cagcgctgcg catgtctgcg ccaccgtagc cgatgttttt gtatttcgta taagagtagc
     7201 cactggtata gctagcaacc ttatctccat atttttgttc ggcgtaatga tgcagccaga
     7261 gaatttcctc atcatctatt ttggcgtcca taacagcacg caccaactcc atattgtagt
     7321 tggcgaattc ttctttcctc aagaattcgt tgtctcgata caattcttta aaggcttgat
     7381 atttcagcac cgggtcagaa gcaaggtagg tgccaccata gttaaccaca aaggatttga
     7441 tctccttgca gtaggcaaca gcagttgcca gcatcatttt tttgtagaca tagccatttc
     7501 ccttgtcctc caaatctgcc ttattagtag cataaaggtc tcctaaggcg ttcaaggttt
     7561 ttagggtaga gccgttaaac atcgagcctg cctctaaaaa cagtgacaga gcgtcctcat
     7621 ctgacaatag ccaatcaaga gcgaccttga ccttttcatt tttcttgaca gcagattgaa
     7681 tggtgtggta gccgacacga ttgacaaatt cgcgctcaag cactaatgcc aaattgtctg
     7741 gattatcata attatctgtg acactattct tgctgagaag ggcatcatac tcttcagttg
     7801 tctttagcct gtcataagac acctcgcttg ataaatcata atctgtcttg agcaacctga
     7861 gatccgcata aacagagtga tcattaccgt tattttttag tgaatttgca attagcttta
     7921 catatttagc acctgtaata tctagatcaa cataaacagc ctcactggtt ccggttactg
     7981 taccagttgt caccaggctt tcccaacttt ttccgtcctt agacttatag atgttaaagc
     8041 taacaccatc gtccttacca cgtctactat agtcaactcc taggtaggct gatagacgcg
     8101 tgtattcatt ggagtattgt tcaacatcat aataaagctg tgaaggagca tgcactgcaa
     8161 ttcccttatc aaatgcaagc acctcgccat caactactag agtaatggtg ccaccggcag
     8221 ggtttttgtc ctgtaaaaag ctgccatgcc caaccttgga cgggttgaca cgtgtctcat
     8281 ctgataagta gatatagtcc ttagcttcag tcttattggt ggtctctact gcttgtgata
     8341 cttctgtctg ctcctgcttt gtggtctctt cggcagaagc ttcggtagct tgctctgctg
     8401 cggctacttg actcttagag tcagttgttt ctgtagtggc agtacctatt actactggca
     8461 gcgtttctga ggagccctca gctgctgtgt cttgcgcagc ggttgctgat tggtcagctg
     8521 cttgttgatc aaccgcttct tgtgcttcta acgtggttgc tatggctgca ctagctgtta
     8581 cttgctgctc atcagcagaa acagttgtca gccctagtgt taaaaataag gttgcaacca
     8641 acacagaggc tgcacctgtt ttaaaggttt taatggcaaa gcgctgctta ccatcagtat
     8701 aaggtttgaa catggtgtct tctcctttaa aaataagata tttaagcaaa ataaagactg
     8761 accaccaacc actacagttg ataatcagtc caacaaagat atcgtactat aggaaattaa
     8821 ttaaaggggg aaaatcatcg cctacagtta atttgattct ttgcgtcttg acacaatagc
     8881 aagctggcct gcacaagcaa taactgcaag agctgctgct gtaaagaatg gattagctgt
     8941 atcagcagtt gccggaagca cttgctgctt atcagctgct ttcttgtcct ccttcttagc
     9001 ttcaggctta gattctggtt taggctctgg cttaacctca ggatctgatg gttttactgg
     9061 atccgctggg tcgattggat cgaccgggtc taccggatcc actgggtcta ccggatccac
     9121 tgggtctact gggtctactg gatccactgg gtctactggg tctactggat ccactgggtc
     9181 taccggatcc actgggtcta ccggatctac tgggtctacc ggatccactg ggtctactgg
     9241 atctactgga tcgaccggtt tagcaaccaa ggctgccttg gcatctgaga gggatttctt
     9301 agcatttaac accttaacca agctgttagt aatagctgtc ggttctgtct cctgagcata
     9361 agctgtctca cccgctgctg cgacctcctt agccttagct agctggtctg tataggcttg
     9421 agcagaagct gctgtatatg gagataggtc tagattttct ccgataagag catttaattg
     9481 gtctaaagca gaacgcaatt ttgcctttcc ttcttcggca atcgcagcct ttacctttaa
     9541 aatagtatca acaactgaat ttgtttctgt agtgtagcgc tctagctcat aaagggaaat
     9601 gtcttttctc tctttatcct tgttaacagt tctatagaag gtacctgctg cttcaatggc
     9661 cttattgtac aattccttca aagactctga tgtcaaagca agatttggat tttctcggta
     9721 aagctctaac agcttagcca aggcttgatc taaggcttca tgcgctacag cagtcttaag
     9781 cgtcgtaaga gcttgcgtta aatcagtcgc agccttatca acatctcctt gtgaaggacc
     9841 aaatgaattt tgaagcttag ctgccgctgc aagcttttgc acaagaccgt catacgcttc
     9901 tttaggatac tctttgccat ctgttataaa aggtgtagct tgattaatag cttcatttaa
     9961 agcattaaga ttaacaagac tagtaatagc ggaatcaata gtagtaacag attgatctac
    10021 tgtattttga tcagggtcac tgtttaaata ggtcttacca atagtaaccg ctgattgcaa
    10081 ggcttgcagt gattcatcag aatacgttcc ttcaggctgg ctgagtttta gcttagcctc
    10141 ctctaacgac ttccttaact cagttttatt gctgttggaa ttttttagtt taaatgtgaa
    10201 gagctttttg gtatcatttt tcccatagaa tacccaagct ttaatagtat aagatccccc
    10261 cggtacagca tatgtaggcg aagctaacat ttcatcagtt aaaaaggaag tacccgcagc
    10321 attgtaaaag tcaaaccata tttttactcc aggggtatca attcctcttg aaccatctcc
    10381 attcgaaata aagtcaaaag tatctccatc attaacagtc ccattactac ctttacgagt
    10441 aaccgtaatt tgactcataa gatctgagat agtaattggt tctcctaatt caactgtata
    10501 ttcttgtgga atatctatgt gccagttcag atgttgacct gtcccattat tttcaaatgc
    10561 actagcagta gtcgtttccg cccctactgt taaagcgcta tcaatattat ccgacaaggc
    10621 aaccaatcct gtgctgaaaa ctaatccaac aagaccacag cccttaagac accgtttcgt
    10681 gaatttcttc attcttcttt ttccttttct agagccctag caggctcgaa caatagcaat
    10741 atgtgtcata gggcagctgc tatcactagt agctgccact ttgatattag cctgattgtg
    10801 acactcaaat atcacttata atttacaaaa aattttaaga aaagtcaata tacaaacggt
    10861 ttttgttaaa ttttttaaaa atataacaaa aaacaagcac gccaatctgg tctataacag
    10921 tttttattgt caatagtgat cgctaaaggg tttttcagcc aacaaaaaaa gagtgaatcc
    10981 ctaactctct cttctagact ttgtgccata tcatcagcta cacgaacagc caagatcaaa
    11041 aaggccagct ctcaatagtc tgtgtcctta ccctgcttcg tctgacagct agggcaaaca
    11101 ccataggcta taactggaat acgggtgacc ttatagcctg tttgctggtg tgcttcctta
    11161 gcgatatcca tcacatctac gtccataaaa tcagcgattg tcccgcaaac ctcacaaacc
    11221 acattgacat gctgatgtcc cataaagtca taataggtcg tcaaatcatt actaattttc
    11281 agctcggata caaagccctc atcaacgaga accttcaaat tattatacac cgtagcaagg
    11341 ctcatattag ggtattgagg ctgtaaatca cgatagattt tatctgcgct ggggtgctca
    11401 gtggactgaa tcatgtaaga aatgatcgcc ttacgcgtct cggtaatacg aatatgcttg
    11461 tcacgtagat gctctaggac attttcatag gcatttagag cttgctgatg tgaatgaatg
    11521 tccaagctta caacctcctc cttttgtaac tatggcacta actagcagga atcttgatcc
    11581 tgcttgctga ttagccgtaa atagtcaatc ttgatacagc gattcataac aatgtcagct
    11641 ttgcctgctg atcgcaaaag ctcctcagct tcttggctat acaagccaag ctgtgcccaa
    11701 aagacctgac cctgacaagc taaaaagtcc tgagcaacct gaggcaaata ctcacttcgt
    11761 cgaaagacat tggcaatatc taccttaaaa ggaatagccg caaggctagc ataaacgacc
    11821 tctcctaaaa cagactgacc tgccagccta ggattgacag ggacaatccg atagccctta
    11881 gcctgcataa acctagccac atcataagca gcagtggttt gacgatcaga taagccaacc
    11941 actgcaatgg tcttggaaga ttcaagataa gaggtgatag tctcatcaga gggattttga
    12001 aatgtatcaa tcatcattta cttccttttt atcaagcaca cccaatagca aatcaacaac
    12061 aggaaaagac aatcgctgcc ggtatgacat agccaaccat ctggctacca agctcaagga
    12121 aaaccctcct tagcatgaca tgccctgctg tttttttctc ttcattatag cataagtttt
    12181 taaaatgcgg aacacaagga ataacagcag ccacaccaag caggctgcca cttaacacca
    12241 ctgctaatct agtctacttg gcctcatacc agctcttgcc ggcactttcg tctacacgca
    12301 gcggaactgc caggctgaca gctgattcca tcgtttcttt gaccagcgct ttaacagccg
    12361 ctagctcatg attaggcacc tcaagcacaa tctcatcatg cacctgaagc agcattttgg
    12421 tctcaaagcc accagctact agggcttggt caagatttat catcgcaatt ttgagaatat
    12481 cggctgcact gccttgaatg ggcgaattaa tggctgtacg ctctgcaaag gagcgaacgt
    12541 tgaactgacg agaattgata tctggcaatt gacgacggcg cttaaagagc gtctcaacat
    12601 agcccttatc cttggcttca cgcacaaccc tttccatgta agccttgata ccagggtagc
    12661 gctcaaagta ggtgtcaata taagccttgg cctgttttct tggaattcca aggttattag
    12721 acaagccaaa gtcagaaatc ccatacacaa tgccaaagtt aacagcctta gcattccgac
    12781 gatcattggc agtgacgtcc tctggctttt caatgccaaa gacacgcatt gccgttgagg
    12841 tatggatatc cgctccctcc ttaaaagcag caatcaaatg ctcatctcct gaaatatgtg
    12901 ctaaaacacg caattcaatt tgcgaataat ccgagctaag caaaacagca tcatcatgag
    12961 atggagtaaa ggccttacga atcaagcgcc cctgctccag acgaatcggg atattttgca
    13021 ggttaggatc aacactggaa agtcggcctg tctgggttaa atcctgtaaa tagcgggtgt
    13081 ggatcctgcc atcagccatg atgtaatcct gcagtccaat cacataggtt gattgcagct
    13141 tagtaatttg acgatagtcc aagatcttag ccacgattgg cgcaattggc gctaagcgct
    13201 ccaagacatc aacagccgtt gaatagcctg tcttggtttt ctttgtcaaa tgaagaggga
    13261 gctgcatttt ctcaaagagt atcactccta gctgcttggg agaattaata ttaaagacct
    13321 caccagccat ttcatagatt tcctgtgtca gttcctcaat gaccacctta ttttgctctg
    13381 ccatttcctg caggctatct tgattgacag caatgccttc gatttccatt ttcgcaagga
    13441 cattggcaag cggcagttca atgtcagtgt agagatcagc ctgctcatgc tctgccagct
    13501 tatcaagcat gactggtcta ctatccagca agacctgaac cttacgcgcc agatgtccta
    13561 acaaaacagc cttgtcaggc acagcacgct tgaccccctt accatagaca acctcatctg
    13621 tatccagtga tatagtggta taaagacgtg ccagagtagc catctcattg tcctctacag
    13681 ttgacaagag gtaattagct aagcgggcat catagctggc agccggcaaa tcaagcccca
    13741 gatgactaag cagaacctta ctgcgcttaa aatcataggt agcaatcggc tgctcaagaa
    13801 cctttttaaa gagctttgta gtgaggagac taatatctgc tgaagcataa atctggcctt
    13861 ggttgcccca agcaaagcca atcagctcct cgcggtgata attatccctc aaagcttcaa
    13921 aataaaacac cgtatcgtct gaaaacatgt ccgctcttat gtcagtaact tcctgataag
    13981 caatctcagc taccggctcc tgtggcaact gactagctaa ggcatttttt agttgaacaa
    14041 aatccatctc atcataaaat tgtgacaagc gatctagatc tggaccctga tagacaatat
    14101 cctccaatcc aatcgtaatc ggagcgctag tgttgatagt agcaagtgtc tttgagagga
    14161 aggcctgctc cttatcatga agcaggtttt ccttcatttt tgaaggcttg aagctatcaa
    14221 tatgctcgta aatcccctcc aagcttccat attcgtgcag gagctttaga cctgtttttt
    14281 ccccaatttt ggtcactcct ggaatattat cagacttgtc tcccatgagc gctttcaagt
    14341 caatgaattg ctctggcgta agccccattt tgtccataag gtaggctggg gtaaactctt
    14401 caaattcagc aactcctttt ttagaaatct caacaacggt atttgcatct gtcagctgaa
    14461 tcaaatcctt gtcaccactg acaatagtca catcaaaagg aatctctgta cgctctgcca
    14521 ttttatcaag cgttccgata atatcgtctg cctcgtaatg ctctagctca taaaaggcaa
    14581 taccaagcgc tcccagcata tcacgaatat aaggaaactg ctcccgaaat tcatcagggg
    14641 tcttggcacg tcctgccttg taatcagcaa aaagctctgt ccgaaaggtt gttttacccg
    14701 cgtcaaaggc caccaagaca tgcgtcggct gaacacgctt catcatgtgg tctagcatca
    14761 aatgaaagcc ataaatcgca ttagtgtgaa gaccgctgtg atttttaaag cggtcaatct
    14821 ggttatagag ggcaaaaaag gcacgaaagg ccactgagga gccatcaatc aaaagtaatt
    14881 tattcttgtt ttccatgcct ttattatacc acacagtgac ctgctttgct ctgaccagct
    14941 acgctttttg caagcactag caggtaaagc agcatacccg tagcttgatc aaaagatcca
    15001 agctgcttga aggaagataa atgactgctt ttgctttatc atcaagacat ttctaccaaa
    15061 aaagagactg agataaaaag agtgacactt tagagagtct taactaatat cctttgttat
    15121 ctaattcatt aacaaacgaa caggcctagt tttcaaaacc tcagaaaact aaacctgttc
    15181 atttgttcta tttgaagtca gactttgtct caatctccaa attgatgaca tcatctgcta
    15241 tgactttcct aagctgatat ggacggaaag ccttctgcaa aatccatgat tagtctaggc
    15301 tacatttgag cgagcggcct tatgactgag tccatttggc caccttatca gcatggctag
    15361 ccacccattt cttggctgcg gcttctggtg tcatgccctg attgatgtca agcataacag
    15421 cctccatatc ctctttttcc caatggaagt gatcaacaat cctatgaaca gctggcaggt
    15481 cggcctttaa gccccgacgt gcaatggtat tgatattttc ctttgagcca aaggttttct
    15541 ttggatctgc caggtatttc aaatcgtact tagcaaacat ccaatgagga gaccaagccg
    15601 tcacaacgat cggctccttt ttcttgaccg cctgatcaag tgaggtggtc atagcacctg
    15661 tcgaagcagc aacgagctcc caatctgcca agttggaata ggccttttgc gtcttatcag
    15721 cagcagtcat aataccagct cccggttcaa tcccaataat ctgttgattg gcttgatccg
    15781 aaagctcctc tatgctgttc acatcgctca tataggctgg cacagcgagt cctagctttg
    15841 ttcccttcag attaggacca agattatcca gcttatcctg atacttttgg tactgctgct
    15901 gatgggtcac tggtaaccag gcacttgttg aaaagtctgc atcgccattt gcgatggttt
    15961 gccacatcac agcattatcc agtggtgtca aggttacctg ataaccctca tctcttaaga
    16021 cctgagcgat aacatgggta gaagccacct cagaatccca ctgcacataa gcaatggtca
    16081 ccttctgccc cttgtctgct gagcttgata acatcgcagc aaagccacgc cccaaagctg
    16141 acaacaaaaa gacagctaaa gcagctagac caagccattt cttggttttt ccagtctgcg
    16201 ttctttcttg cggcttaccg ttaaaatgct gagtcatacg atccaaaata atcgccaaga
    16261 taacaagggc caaaccacta acaaagccac gcccaatatc agcatgctgc aaggccgata
    16321 ggacctcacg tccaagacct ggagcaccaa tcattgagcc tgtcacaacc attgataggg
    16381 ccaacatcat ggtctgatta acacctgcca tcatcgtatg ctttgccaag ggtaattcga
    16441 ccttcagtaa tttttgttta ggggttgacc caaaggcatc tgaagcttca accaattctg
    16501 tcggaatatg acgaagcgct aaattggtaa aacgaacagt cggcggcaag gcaaagataa
    16561 ccgacgcaaa gacgccaggg accataccaa tgccaaaaaa ggcgacagcc ggaatcaaat
    16621 aaacaaaggc tggcatggtc tgcataaggt ccagcattgg attaatcacc tggtgaacaa
    16681 tcttattttt agccatccaa atgcccaagg gaataccaag caagacagag atgaggcttg
    16741 ctaccaaaac cagcgtaaag gtattgatca gctctgccca caggccttgg ttatagacaa
    16801 ataacaggcc caggagggta aagatcggca aaggccattt ttttcttgcc aagaaaaaca
    16861 tcgcacaggt aaccaatagc ataaacagta acggattgat aaacaaaagg gtctgcgtga
    16921 tccaatccat caaagcattg cccacaagct gcagcagatc aaagaagcct gaaaaggttt
    16981 ttgtcagcca ctcagttagt tgctcaacca gctgtgccac tggtagagtt gtttgtaata
    17041 ggttttccaa aatacagtct ctccattcta attaaggtcg tcatctggaa tattagccaa
    17101 ggcttcaagg acacgcccac gaataataac ccctaacaag cggtgctgct catctgtcac
    17161 tgcaattggc gcagaagagt cataaatcaa gggcaaaata tccgtaataa cagtatcctt
    17221 tgagaccgtt ctgacattac gatcaataac ctctgacaag gggagctttt tctgacgtgc
    17281 ttcaatcgct ccgtctgctg ttaggcttcc tattagctga cgacgacgat tggttgccat
    17341 gagcatagac acctcctcat tgtgcatacg attcaaagcc acctgcggac cgtccagatc
    17401 aaccgttgtt gtgataggct taatcataat atgctgagca gtcagcacct ttgagcggtc
    17461 aacgtcctct acaaattcac gaacaaaatc attagccgga ttggttagaa tatcctcacc
    17521 cgtcccaatc tgcatgatct gaccgtcctt catcaaggca atacgatcac caatacgcag
    17581 agcctcattc aagtcgtgac tgataaaaat aatggtctgc ttcatcgtct cctgtaattc
    17641 tagcagctca tcttgcatgt cacgacgaat caagggatct aaggcagaaa aagcctcgtc
    17701 catcagcaaa atcttagggc tgtttgccaa ggcacgcgcc aagccaacac gctgctgcat
    17761 gccaccagac aattgatcag ggtattggtc cctgacctca agaagccctg actgatcaag
    17821 cgcacgcttt gcaatctctc gacgctcctg ctttggtacc ccacgcagct ccaagccaaa
    17881 ctctgtgttt tccaaaatcg tcttgtgtgg aaaaagagca aagctttgaa aaaccatatt
    17941 catatcatgc ctgcgaactt ctctgagctg atccacagac agtttagaaa tatcccttcc
    18001 ctctaataaa atagagcctg ctgagggctc aattaatcga ttaagcatac gaacaagcgt
    18061 tgatttgccg ctgcctgaaa ggcccatgat cacaaaaatc tcgccttcct gaacctcaaa
    18121 gctggcatca tagaccccga cagtaactcc tgtcttttta aaaatagcgc tcttactttt
    18181 accagccttg atcatttcaa gagctgcttt ttgttttttg ccaaacaatt tactcaaatg
    18241 cctgacctct aaaatagttc ccattctttt cctctcttgt tctcttcctc gattaaagct
    18301 aaattagctt aatagatttc taaaagtgcc accacaattt taaaataatg aggtcacttt
    18361 ttgcttaaaa aaagagtctg cctaaacaga acacattaat tatataatat atggtcactt
    18421 tttgtcaagc tggacgcttg ctacccaagt atcaggatcg tcctaagcag tgatatcact
    18481 agtcaaccaa gcacttaaca gccctgaaca gaccacagca agcaggcctt tctgacactt
    18541 agcgccttga gagcttaccc agcagcctcc tctagctgac ttgattgacc tatctgactc
    18601 ttgtcctgca accaaaccaa tgcttagact gccaagcaag ctcccaatag caataagatc
    18661 tgctaagcaa agcgttagct tgctttgacc atagctgcta gtcatgtcta atagcactct
    18721 agataaatca aaagccccac ctagcaaggc tagatgaggc aaaataggtt tagagaaggg
    18781 ctttaaactg aatatttgag tcttccaaga agcagtcgtc aaagccacgt gggtgatgat
    18841 actcgatgcg atcctgatcc tgtggatagg tgtatttgcc accaacctcc caaatgaatg
    18901 gatggaattg gtattgcaag cgctccttac gcatcttcca aagctctagg atttcatcag
    18961 ttgaggccat gaagtttgac cagatatcat agtgaaccgg aatgacaacc ttggcgcgga
    19021 gattttctgc catacgaagt aggtcaacag aggtcatctt atcctgaata ccgattggat
    19081 tttcaccata attgttcaag acaacatcaa tatcgtagtc acgtccatgc ttagcaaaat
    19141 agtttgagaa gtgggagtct gcaccatgat agatggttcc tcctggtgtt tcaaaaatgt
    19201 agttaacggt tttgcgagct aactcttcgt cagtcactgg aagtcctgct agctcgccac
    19261 cattttcctc agcgccagca actggtaagg taacgataca ggtacggtca aaggattcaa
    19321 cagcagtaac cttgatatcc ttgaatgcaa agctatcgcc tggttttacc acgatgatac
    19381 gatcctttgg aacaccccag ctctcccaaa tcttgccgca ctcataaggg ccaacaaatt
    19441 tgacatggtc aagctttgga ttgttgataa tggctgctgc agtattgata tcaatgtggt
    19501 cactatgata atgagacacc aagtaatagt ctaactcatt aatcataaag ggatcaataa
    19561 ccattggctg agctcttaga tttggttgta gcttgcgaac ccctgccata ttggccattt
    19621 ggtgaccacg aaccatgtct tttacttttt tagttgcctt tccacgattg gaccataggt
    19681 ccatgacaac attggcacca cccggtgttt tgatccagat accgcagtta cctagccacc
    19741 acatagagaa atttccttca ggcactacct cttcttcaat ttcttcgttt agccaggttc
    19801 cccattctgg gaaggtgcta agaatccatg attcacgagt tatatcttgt actttagcca
    19861 ttatgtttcc tccaaaatga atttttatct atactctaag tatagacctt ctttattctc
    19921 ataaaaagac caagtgtcac acactcttgt gttcaaaact ggactgaatt ttggctcaaa
    19981 ataaactaaa agccccagcc ttctcctaaa ccaatagaca gctgaggggt ccttatcaat
    20041 aggcaagcta gtagcttaca ataattcgtg atgaatgagc ttttcaattt ttgttttcaa
    20101 ggcatagcgg tcagcatcgt ccttaacaat ggtctcgatc gccttttcta gctcaaggga
    20161 aaaacgagag ctatcactca agcgcccctg ctttgaaaaa cggatcaatc taataatgtc
    20221 atcatcgctc aaaataggat tgacaatcag tacgggaaca agagcctcca gtgcgtctgt
    20281 tgttgatacc acaatgtcaa cagacatcaa atcaaagaca ctctggtatt gctctgttgt
    20341 aaagacagcc tcgatttgac aattgggcaa ataacgctgg cactgcttca acagcagctt
    20401 ttgaatccca atgccatcat ctgaaacgat aacaagcttg gtcttgtccc agtcagcatg
    20461 actatggcgc agctctcctc ccagatgaat cgttagataa gccacgtcat catctgttag
    20521 acggatctgc caagcctgct ctaggattac agcacaggat tgagccatag caaagagctc
    20581 ctcgtatttt tccttaatat ggtctgttaa aggattgatc gaaaaaatcc cataggcctt
    20641 tcgataaaca agggccttgc aatgcctggt cagctgtcta agcaagtcct ttttgtgggt
    20701 aaaatgcagc tgatagcgca gctccagctg atcgataaaa tcaccaatag tggctcgcat
    20761 ctgctcataa tcctgacttt caacatggtg atcctgatct tttctaaagg atagcatcag
    20821 catggctatc atgcctacct caatgtcatc taaatgcagc ttgaaattgt ggtaaagctc
    20881 actagccaat gccttagcaa tctggtattc cttgcgcttc caaatcaggt taaaatccct
    20941 tttaagcgct gttttagttt ccgaatgcaa ttgcatgttg cgatagctaa gcaggataaa
    21001 aggaagaatt tgcagcataa actgactatc ctgaatatta attgttttgc ctaggctagc
    21061 ctgagacaaa aagaggtatt cgtgaaaata atccaaaacc tcctttgaaa aataagctga
    21121 caagccttgt gtctcagaaa gcttatgatc aaaaagctca ataaagctgc tattgcctcc
    21181 ctgataaaca cctgccaata ccttgtaaag gtactgaatc aaagccatag ggtgacagtc
    21241 aaagtaatag cccttggcct tggtggcatg cagctgaatc ttattgttat agctagacaa
    21301 ttcctctctc agttcagcaa ggtcatttaa gatggtattt ctggaaacat cattaatcat
    21361 catgagctta tccagtgtca cccgctctgt tgccactgca atataaatcg ctgataagct
    21421 cctgcgctca tcacccttca tgacatagtg ataatctgcc acttcattga ggagctgttg
    21481 gcaggcagcc ttttgctcac tatttagcaa gatgccaacc cgaggatagg agacaatttg
    21541 agcaacatgg ctgggcagcg cttcgttaat tttatccaaa tgataataga ttttgcgccg
    21601 cgactgaccc aaggcagctg aaatcgccat gactgtctca gcctccttca atcgaatcag
    21661 atatgacagc agatcatagc tttttttatc caaaataatc acgttcatac ctcccttcta
    21721 taaaacatca ctaccacaca gccttatcag tttaccattt tacctatctg taggaaagaa
    21781 tactaggcca aagtcaattt ctaaatagga aaaaacgaac gatcattagt tttctgaaga
    21841 taaaattcct aattagttcg cttttttctt ttataattgt aatagttgaa ttaattatta
    21901 aactttgtct aaaataagag gctttttatc ccagattgca acaagggtta acaccttgac
    21961 cttaagccta gctaagcagc tctcactaag ttactagctg ctgccttaat gccggctacc
    22021 tttttggcca taataggcat ttggaccatg ctttctaagg taatgcttgt ccataatata
    22081 ggttggagct ggctccacac gaggattgat ttgttctgtc aggcggttca tcttggccac
    22141 ctcttcgagc accactgagt gataaaccgc taattcaggc gtcttgcccc aagtaaaggg
    22201 accatgattg cgaacaacaa taccaggcac tgccatcgga tcaagaccac gactagcaaa
    22261 ttcctctaaa ataaccgtac ccgtttcttt ttcataggct ccattaacct catcggcagt
    22321 tagagagcga gcacatggaa tggggccata aaagtaatca gcatgagttg tcccataaaa
    22381 tggaatatct cgcccagcct gtgcccagcc aaccgcttct gttgagtgtg tgtgcacaat
    22441 cccgccaacc tctggccatg ccttgtataa ttgcacatgg gttggcaaat cagaagaagg
    22501 gttcagctct ccctcaacaa tagtgccatc taagtctgta acgaccatat tttccggtgt
    22561 taattggtca tagtcaacgc cgcttggctt gatgacgata cgtcccagct cacgacagac
    22621 ctctgagaca ttgccccagg taaatttcac cagcccatgc agcggtaggg ccttgttggc
    22681 tgcacagaca cgttcacgca tttcttgtag cctttttgcc attagcttaa ccccgctttc
    22741 tcaatcagtg gataaaggaa atcctgtgcc tccttgatgg cagctcttgt ctcctctaca
    22801 gtttcacagt tttctgacca catttcaatc aaaaatggac catgataatg cgttttcttg
    22861 agcacatcaa acattgcttc ccaatcaaca cagccttgac cgaatggcac atcacgaaat
    22921 tgccctttag atgtttctgt cacagcatag gtgtccttta gatgcaaggc agcaatagac
    22981 cgatgcccat tgtaaaattc actccagagg tcattatgcc aagcagagac attgcccgta
    23041 tctggataga caaagagata aggggagtca atttcttttt ccacagctag gtatttctca
    23101 attgagttga taaaaggatc gtccattatt tcaatggcta aaataacctg agcttcctct
    23161 gcccaagtgc aggcctgtct gagatttttg ataaagcgcg cacgcgtttc aggtgatttt
    23221 tcttcataat aaacgtcata gccagccaat tgaatggtac gcacaccaag atcctgtgct
    23281 agcacaatgc attttttcat tagctctaat gatgtcgctt ctgtttctgg attgctagag
    23341 ccaagtggat aacgacgatg accagagaag caaatgcttg ggatacgaac ccctgtttca
    23401 taaatagcct tgacaatgtc tagtcgctcc tgtttactcc aatccaagcg cgctaggcga
    23461 gcatctgatt catcgacaga catttctaca aaatcaaagc ctaatacctt tgcaaattgc
    23521 aagcgttcca gccaagtaaa atgctttggc gttgcttttt catatatacc aataggacgc
    23581 gccatattgt tacccccaaa tgcgtcgaat ctcgtcttta aaggcacgtg ccgctgctgc
    23641 aggatcctct gcttcagtga taccacgacc tgcaataaag gtaaagacat taaccccttc
    23701 aaagagcttg agggtattga tatctaagcc acccgtcacc gatacacgaa agcccatgtc
    23761 aatgagggct ttgaccttgt tcagatcttt ttcaccccat acttcaccag cgagtagggc
    23821 gtcacgtgat tgatggtaaa tcgcctgtga aatgcctgca tctagccaca attgtgcctg
    23881 ttcataggtc caatcaccat acagctcaac ctgaatctcg ccacgttccc cacgctcttc
    23941 tttgatggct ttcagtgcgg ctgccatggt tggaatagtg gcacagcaaa tacaagtcat
    24001 ccagtccgca ccacgcttag cattattctt agcaacagta ccgccagcgt ctgcacactt
    24061 ggtgtctgct acgatgatct tctctggaaa taagctacgc agcacctcaa ccaattcgct
    24121 gcctacttga agcaggcaaa ctgtccctgc ttcgattaca tcaacctcgt gaccaactgc
    24181 aacagcagcc ctgaccgccc cctgcaaatc agaatgatct aaggcaacct gtaattttgg
    24241 aatatgtgtc atgattttct accaagagcc cgtagcaccg ccttcaatgc ttaatagcga
    24301 gctcctatcc tttctgttgt gtttgattcg tttagtgatg atggcttgtc taagaatcca
    24361 aatccaagcc ctctaaataa ggactatttt tggactcgtc caccaaagcc aaaacctctg
    24421 ctggagtgtg acaggcaact aagcgcgaaa tagcgtcttc cagttcaaaa agggcgacaa
    24481 tctgtggaat agcaactgtt gtatgaatag aaggatcagt tgccgccaag gttagcaata
    24541 ccgaagcctc tttgccatct gaaaaggtca ccggcttggt cagtgtgata agagcaaagg
    24601 catttcgctt gacccctaca ccagcctctg cgtgtggcat ggccattccc ggcataagga
    24661 cataataggg cccgtacttt tctgttgatg cgataatagc gtcataatat tcagaggtca
    24721 ccgccccgct gtcaatcaaa ggctgaacag ctagcttaac cgcttcctgc cagctagctg
    24781 ctgacaagcc caagcgaata gagttgtttt cgataaatgc tttttttaaa ttcatataac
    24841 tatcctttct aaatcaaatt ctttggccag acactttttg cctcactcct atctagctga
    24901 taaagagaaa gagctggaat ctctcttcac aactctcact ccatctatcc ttactgaaag
    24961 ttgattgcta cagcttagct tacagccaag tggctgctct taggctcact atcatttgcc
    25021 atgagcagca ctgatgtcat cagggccgct ctaaagcacc gcctgtagct tggttttgat
    25081 ttcattgtcg tccataagat tatctagtcc aaccaaatga ccctttgtac gcccatctaa
    25141 ttcatgaatc aggtgattag aagcaaccac aatatcatag cctgaggcaa gtccctttgc
    25201 ctcacccact gagcaagaag cagactgaat atcagtcacc ccaagctgac gaagtgcgtt
    25261 ttcaaccttc attttaataa ccattgatga ccccatgcca ttaccgcatg ctgtaagaac
    25321 cttaaccatt tattttcctc cgaatatatg ataatttgat atgaatgaag acctgcagaa
    25381 gtatatcgac aaactcctac cagcctgtgc taaaagacga ataagcagct attatcacct
    25441 tgcttattgt gcttcaccgc ggtagtaagc ctctttatcc ttagccctag caaattgtag
    25501 ctgtggaata gcaagtaaga agacacacac caccacatag cctgcaatac caaggaactt
    25561 gaagagataa ccaaatggaa gccaaggaag caccaggtca atattgccat gataaccacc
    25621 tgtcaagccc aacagaccaa ctgccactgc acctaaggca acctgaagaa tacctgatat
    25681 aaaggataga gcaacagctg ccttccagcc accacgctta tctgcataaa cagcaatcgc
    25741 agcattatca aagaagaccg gaacaaatcc tgtgatgatc aagattggat ttttaaagat
    25801 cacaagaagt gcaatagtga ttagctgacc gataagccca aaggtaaatc ctgacaaaac
    25861 agcgtttgaa gagccaaagc catatgacgc tgcaacgtcc accgcaggaa atgaacccgg
    25921 aaggagctta cttgaaatcc cttggaaggc attggtcaac tctgacacaa acatacgcac
    25981 accctgcatc aggataaaga gataaactga gaaagttaag gaggtttgca aaatatacat
    26041 aaagaaggcc tgcttagctg gattaaaggc accagcacct ataagttctg cattagacat
    26101 catatctggg ccaagcacag ccaagatagc accaaagaaa accagcatta gagtggcaga
    26161 agcaaccacc gtatcatgaa aaatcgttaa aaagcttgct agcttaagat tgtcaaggtt
    26221 ctcttctttt ttaccaaaga aaggcgccac cttgtcaaca aaccagatcg caaactgctg
    26281 ctggtgccca atggcaaagc ctccaccacc tgtcaagcgc tgagtcgcct caactgtcat
    26341 attggagctg acagcccagt aaaggccaca gataataccg accgcccaag caccaaaagc
    26401 attttgaagc tgagggatta aaagaagaac aaacacagag atggttgccg cctgctgcac
    26461 catgatatga cccgtaataa agagcgtacg aacctttgtc accttacgaa gcgccactag
    26521 caaaatattg accccaaaac cgatcaaaag ggctgtggtg gcaacgctga tggatcccat
    26581 ctcctctagc ttggtattgg ctgctgcaag tccaaagtaa gggtcaataa ctgcggcctt
    26641 taattcaaat ttcttaccca atgccactag gattgggcga aaggtgttaa ccaagccccc
    26701 agcaccaaca ttcaaaatca gataaccaac cgttgcctta acaaagccag caaatacttc
    26761 atgcaggggc tttttaagca gcaaataccc aatcaaaacc aaaagaccta caaagaaagc
    26821 cggattttgc aaaatatctt gcgaaaacca gtttagggga gctataagca ttttcataag
    26881 aactacctct tttcacagtt aataaatatg atattttcta tacaataatt gtaaacgatg
    26941 taagcgttta aaaaaaagac caacaatcac acaaagaagt gttcaaaaat gtactgaagc
    27001 caatttccag ctagctctga tcactgttaa agcactatca ttaatctcta attaataacc
    27061 aaacacatca caacaatatc gggctaacac aaaaataggc cagcccatac tgcccagcca
    27121 aaacgaaaca agcaatcaat tcaaggcact taaccctgtt ttatatcgta caaagccctt
    27181 ttaagatgat tttgtttgtt tcctaatcgt aaattagtta tctgatccgt tctctcctca
    27241 gatatactca cccttatcta attctactgt caaatagcta cttactcata agcaaatgaa
    27301 tattaagcaa ccaccaagct acaataaaag accttaccct gttggcaaga tcttattcat
    27361 tatacaattt ttccttctgc gacatggact acctcatcac acaagtcttc aatatctgtc
    27421 ttcagatgtg agcttaaaat cacaagccca tttttgctaa catctaaaag caattttttc
    27481 gtttgctcca cgctcctgtc atctaatgca ttcattggct catctaatat aaggatctta
    27541 gggtgatgca tcaaggcctg aattaaccct aattttttct tagtgcctag cgattaatgc
    27601 ttaaatgctg tttgactaaa ctgatgtaaa tgataaacat ctaaccaaaa agctaaatca
    27661 atatctctag ccttaggaga gattgaccta agcaactcta gattttgtaa caatgttaaa
    27721 tgtgcaataa actctggatt ctcaatcaaa atcccagcat cctcgatata attatggtac
    27781 tgtctaattt ttttattgtc ctgataaaca gctccttcat ctaatttgat ataaccagct
    27841 aaggccttaa gtatcaaggt ttttcccgaa ccattaatac ctaccaaacc atagatatta
    27901 ccttctttaa aagtaagatt aatatcatct agaacaaggt tacccttata cagttttcta
    27961 ccatgttcaa tccgtaacat ctcagctctc cttataataa ttgtcataaa gcatatgtac
    28021 caatactatt agcagcaggc accaccaaac atcaaacaaa aagtaacgta tcaaggtgag
    28081 actagcaaac aagatcatag ctactacagc agatgaggca tagcgtatca taacataaat
    28141 caagcaaata tctatagtaa gccaagatac cataagataa catagtcgtt caatatgata
    28201 tggtgcacca taataggtca tcaatacacc taatattaaa acgataaaaa gtaaccactc
    28261 tttaatatag aaaatcgtac tcgtccgcca tagcttgtta aaaaatacca actgacttcg
    28321 agcatgaaaa cgaaagattt ccttagttcc ttcagccaaa tccgccaaaa atgaaatcgt
    28381 aaaataaaag ctgttgaagg acaagcctag caaggtgata accttgacaa aatcagctgt
    28441 ctccccttca atcactggaa acggcattag caaccgatag cacactaaat tatgaaaatc
    28501 tcgctcccca gtcatattag ccttaatcaa taaaagatgt attagtaagc cagtaagaca
    28561 tgctttcatt ccaacaacca gcaggttaga taatttcatg gtgcttcctc aattttaaaa
    28621 cgatgcacac acccactaag cctaaataag gtgataaaag gtaaggaata tcagcatcac
    28681 tataagatgt tgacatcaaa gaagtcataa gaacatattt gggaggtaaa tagctatata
    28741 acaacggtga caaagcccac atcaaaatca aatagagcat gcttgactta ataaaggatt
    28801 gaagatagtc aacaagaaaa caaacgaaat acgtatgaac gaacaaagct aacgatttta
    28861 ctaagcaata gtaagctata aaggttgttg ctccttgacc aaaaaaacgc aatattgagt
    28921 tttgatcaaa ataaggcatt aaattaccgt tcatatgggc aacaccattt agccaagaca
    28981 ctaaagtcaa agcaaatatt acaatgtaaa aactcagtaa aacatataag ctcaactgaa
    29041 gctttaaaaa aatacacctt ttaccatagt cagactttct gccaatgagg tatttaagat
    29101 gtcttgactt aaggtaatag taggcatagg ccactaaaat catcactagt ggatagataa
    29161 aagattgata aaaactaaaa tcaaacacca cactatccaa acgtatcata ctcaacaata
    29221 gacttttctt tacctcaatt ccaccagata aatctactgc acttgtatca aaaaataaga
    29281 tatgcttcaa actgtcaaaa taaataaaac ctaaaaatag taacgggact aatggataaa
    29341 aatagcgaaa tggaaataat ctatactgta gcatttatga ataactcccc tacaaaaaat
    29401 caaggaaacg cctcgttact aactcaattc acaattgtag atatttacca attgtctgga
    29461 gaccaactac cactaatggt tgttgctccg tcccaccaat tttcacgtac cagatgcaag
    29521 gcataaaggt acccactttt agtatcctgt gtataaattc ctctgtcgcc tgtccaagtt
    29581 ttatctatat cacttcttct ttgaccgtta ctattagcta gatagtgcct taccacaatt
    29641 tctctattac gtcctcttga atctaaatta acgacataat aaggcgccgc actcttcaca
    29701 agataatctt tcgtccttcc aaaagatgac gtgattctaa aattttgcaa gtaaccaatt
    29761 tgtcgttctg ctataactaa agaactaatc aataatgtag aagctacaat tgccaataat
    29821 ccaatcttaa ttttgcctaa ttttattttt taataa
//
LOCUS       DARYXW010000015        29407 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.015, whole genome shotgun sequence.
ACCESSION   DARYXW010000015 DARYXW010000000
VERSION     DARYXW010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29407)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29407)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29407
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.015"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(37..1368)
                     /locus_tag="TV191_000547"
     CDS             complement(37..1368)
                     /locus_tag="TV191_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HEL1507085.1"
                     /translation="MEFLGPIGVLLGIIAIVYFSLKEIHITIAAPMATILVVLLNSMP
                     LVESLLGKEPNNYMGALGGYIMSYFAIFLLGSILAKLMEVSGATVSIAEFILKKVGYQ
                     NPYRILVAIFIISAILTYGGISLFVVMFAVLPLARSLFKKMDLAWNLIQVPLWLGIAT
                     FTMTILPGTPAIQNVIPIQYLNTSLTAALVPSILGSVGCIAFGLFYMKRCLTKSLEVG
                     ENYATYTSQTNEDTTERVLPPFVVSILPLILLIVIAIIGSLLGDEFVKKNIIYVALLT
                     GIISAIVLFNKYIDKKIATLSIGASGAVGPIFATASAVAFGSVVTAASGFGVFSDIIL
                     NIPGPPVISLTVLTSAMAAITGSSSGALGIVMPNFAQYYLDAGVSPEIIHRVAAVASN
                     ILTIVPQSGVFLTFLSLTGLSHKNGFKQTFITVFGGTLVAESIIMLTSLFF"
     gene            complement(1459..2238)
                     /locus_tag="TV191_000548"
     CDS             complement(1459..2238)
                     /locus_tag="TV191_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HEL1507086.1"
                     /translation="MNMSKQVVFVTGAASGIGKQIGETFLKEGKIVVFSDINQEKLDA
                     VVDEYTTKGWAADSVLCDVTNEEAINKAIDYTVEKHGRLDILVNNAGLQHVAMIEDFP
                     TAKYEFMLKVMLTAPFIAIKRAFPTMKKQGFGRVINMASINGVIGFAGKAAYNSAKHG
                     LIGLTKVAALEAAELGITVNAICPGYVDTPLVRGQFEDLSKTRKIPLENVLEEVLYPL
                     VPQKRLIDVQEIADYVSFLASDKAKGITGQPVILDGGYTAQ"
     gene            complement(2269..2913)
                     /locus_tag="TV191_000549"
     CDS             complement(2269..2913)
                     /locus_tag="TV191_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HEL1507087.1"
                     /translation="MVKELSKEEIQERIAKRVALELPNNSLVNLGIGLPTKVARFLPE
                     GVTIMLQSENGFVGLDKVGDDIDPTIVNAGGQPVGIVPGGAFFDSTTSFGIIRGGHVD
                     ATVLGALQIDEKGNIANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKWKILKE
                     CSLPLTAAGVVDKIVTEMGVFTVTPEGIAVEEIHPDYTFEEVQEATEARLIYHN"
     gene            complement(2919..3569)
                     /locus_tag="TV191_000550"
     CDS             complement(2919..3569)
                     /locus_tag="TV191_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HEL1507088.1"
                     /translation="MNKRISIEEAVNLVKDGDTIMVGGFMTNGSPERLIDALVAKGVT
                     NLTLICNDAGFPDKGVGKMVAQHRFRKIIASHIGLNKEAGRQMTAGETVIDLVPQGTL
                     AERIRAGAYGLGGFLTPTGIGTLVEEGKQKLQVNDKDYLLELPLKADVALIFADKADE
                     LGNLCYKGSENNFNQVMAANAKVTIVEAREIVSLGDIEPIAVQTPGIFVNYLVEGE"
     gene            complement(3584..4774)
                     /locus_tag="TV191_000551"
     CDS             complement(3584..4774)
                     /locus_tag="TV191_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HEL1507089.1"
                     /translation="MLVKEVVITTAVRTPIGSFGGAFKSVSAVQLGKVVVEALLEKSG
                     VKPEQIDEVIFGNVLHAGLGQNVARQVGITAGIPNDKPAFTVDMVCGSGLKSIELAAQ
                     SIVCGDSDIIIAGGTENMSQASYVLKDYRWGGRLGDGKIIDTMVNDGLTDAFHDYHMG
                     ITAENIAKNYGISRKAQDIFALASQEKAAAAQAAGRFVDEIIPVPVPQRKGDPILVAE
                     DEYIKAGTTLEKLTALCPAFVRDGSGTVTAGNASGINDGAAAVLLMSRDKAEELGLPI
                     LGAIKGYASAGVAPEVMGTGPIPSTQKALAKVGWTIEDLDLVEANEAFASQAISVVDE
                     LGLNAAIVNVNGGAIALGHPIGASGARILVTLLHEMEKRQAHKGLATLCIGGGQGTSV
                     LIEK"
     gene            4966..5868
                     /locus_tag="TV191_000552"
     CDS             4966..5868
                     /locus_tag="TV191_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEL1507090.1"
                     /translation="MDIKHLRFFIAIVENNFNLSRTAQQLYISQPTLSIMINDFEEKQ
                     GIKLFNKKYNKILGLTMTGKQFYEDSLEVIRKYDKMHQNLFSTNQKLDGNITIGIPPL
                     ILSIVFSKIMPEIILENPNIHFNIKEYGANRLRQELILENVDIAILLHPERIAANTID
                     SFQIQESELCAFVSKNHHLANKKILTWIELHNEKLAIFDKTFMIHHLIKEKCKYTDIN
                     PQIILESASWDFLINSTRINPQLMTIIPKPTVDSYGFQDIVAIPMENPIPWKVMVSRL
                     KKDHYSTIEEYIFNKMLEKFHVIE"
     gene            complement(6765..7907)
                     /locus_tag="TV191_000553"
     CDS             complement(6765..7907)
                     /locus_tag="TV191_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507091.1"
                     /translation="MKALLPFELKKLIRTKSVLGMFIVSLLAIFGLFYINFFNGQISG
                     SSIDKIHGRDAVEINKRFAEEHTGQLSNELLIRTIKDYTLGGSSKNPVFNVYGYYVTS
                     HFDPKFRDYYFNLKKEETIDFSKITPKSQTALGSYLPFKELKLGNFAPWNQLFLVINS
                     AYILLLLLSVYFIAPVFSGDTAKNMNPILLTTRYGRNKLTIAKIISSYLISTSVFVTF
                     YAIILAVFVWYFGLSGWDTSVQLNLYWINSNVNIMAFPEKMTLLGTFINLVTYQFIGL
                     ILITAITILISSKVKSPLTGFALSAASVFVPSFLMDIFQAGIPHKVLSILSVSTASTP
                     NIMLKLAYDGFFGSFWVDGLVIVMIRLAFAFLCLYLAYLSIKRVSQ"
     gene            complement(7904..8767)
                     /locus_tag="TV191_000554"
     CDS             complement(7904..8767)
                     /locus_tag="TV191_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1507092.1"
                     /translation="MLLELNQLSKSYGSKNILRRITTQFTPGLYGLLGANGTGKTTLL
                     NLISHFTTPDEGEILLDHKPQSEEFYQHIGFLPQQFSYYGRFSGRDFLLYMAALKGIP
                     KHKAKQETDELLKLVDLYDVRLKRIASYSGGMKQRLGIAQALLNDPKILILDEPTVGL
                     DPKERVKFRNIISELSANKIIILSTHIVSDVEAIAKEIIILKNGQFIHKSSSQELLKT
                     IFGKVWEFSVSDGSPLPRHGQYAVVNEKLVSSSRVFRVVSDEKPNQLAQLVSPTLEDL
                     YIYHFREEQVL"
     gene            complement(8778..9104)
                     /locus_tag="TV191_000555"
     CDS             complement(8778..9104)
                     /locus_tag="TV191_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator
                     DNA-binding domain-containing protein"
                     /protein_id="HEL1507093.1"
                     /translation="MKYVILYKNRSVVKLPISETYDVTTHSSKPHTVVFVTLKGEFGA
                     ATSLRQIEGESAGKLKRCHRQYFINESKISGFDYATRIIKVTDSRISYRRSLLSTELQ
                     VLSRLI"
     gene            complement(9708..9863)
                     /locus_tag="TV191_000556"
     CDS             complement(9708..9863)
                     /locus_tag="TV191_000556"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507094.1"
                     /translation="MTVDAEKASQLDLGIENAGWFHFKLTTAIKLKQVEKVFLFTAIF
                     NRVDEFI"
     gene            complement(10111..11007)
                     /gene="era"
                     /locus_tag="TV191_000557"
     CDS             complement(10111..11007)
                     /gene="era"
                     /locus_tag="TV191_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEL1507095.1"
                     /translation="MFKSGFVAILGRPNVGKSTFLNHVMGQKIAVMSDKAQTTRNKIM
                     GIYTTETEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVETVLFMVPADEKRGKGDD
                     MIIERLKAARIPVILVINKIDKVHPDQLLEQIDDFRSQMDFKEIVPISALQGNNVETL
                     VQLLKDNLEEGFQYFPEDQITDHPERFLVSEMVREKVLHLTQQEVPHSVAVVVDSMKR
                     DEVTDKVHIRVTIMVERDSQKGIIIGKQGAMLKKIGKLARRDIELMLGDKVYLETWVK
                     VKKNWRDKKLDLADFGYNQKEY"
     gene            complement(11143..11544)
                     /locus_tag="TV191_000558"
     CDS             complement(11143..11544)
                     /locus_tag="TV191_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEL1507096.1"
                     /translation="MASQDNNKRKWKNRTVIASLEFALTGVLTAFKEERNLRSHLLSA
                     LLASLAGIVFGISAIEWLFLLLAIFLVITLEIVNSAIENVVDLASDYHFSMLAKHAKD
                     MAAGAVLVISGYAVLTGLIIFVPKIWRMLCH"
     gene            complement(11525..12022)
                     /gene="ybeY"
                     /locus_tag="TV191_000559"
     CDS             complement(11525..12022)
                     /gene="ybeY"
                     /locus_tag="TV191_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018167004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEL1507097.1"
                     /translation="MYIEMIDETKQVSQEMMEQTIDLLNFAAKTIGKEDKEMAVTFVT
                     NDRSHALNLEYRDTDRPTDVISLEYKPELPIAFSQEDLELDPDLAGMIQEFDAYIGEL
                     FISVDKAHEQAEAYGHSFEREMGFLAVHGFLHINGYDHYTPEEEKEMFTLQEEILTAY
                     GLTRQ"
     gene            complement(12371..12997)
                     /locus_tag="TV191_000560"
     CDS             complement(12371..12997)
                     /locus_tag="TV191_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1507098.1"
                     /translation="MASFFEKLAEHRYLETERLCLRPVTLDDAKAMFDYASDEETVRY
                     SFPANQTIEETRQVIASVYLASPLGRWGIVLKETGDFIGTLDLHHIQLDLGRAEIGYC
                     LHKHHWGRGYATEAVKAVLVLCFEALGMNCVIAKHDKANPALGRVMAKSGMCFSHEEP
                     YAKRDHLDSNRFVTVLHYYLTKEDYDKQKSLASANKPDRYLHNSFESS"
     gene            complement(13052..13627)
                     /locus_tag="TV191_000561"
     CDS             complement(13052..13627)
                     /locus_tag="TV191_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEL1507099.1"
                     /translation="MTELLQAIMADPANRDYTKKGIEPLYAAPQTARIVIVGQAPGIV
                     AQETRLYWNDRSGVRLRAWLGVDDRTFYQSGLFGVLPMDFYYPGKGKSGDLPPRKGFA
                     AKWHGPLMALMPQVELVVLVGQYAQQYYLGEGCRRNLTETVQHFEDYLPDYFPLVHPS
                     PRNQLWLAKNAWFEEELVPVLKDKVRQILRG"
     gene            complement(13674..14774)
                     /locus_tag="TV191_000562"
     CDS             complement(13674..14774)
                     /locus_tag="TV191_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEL1507100.1"
                     /translation="MHYSTDISLNHPDDLLALFGSNERHLKMIESHLNVVIHARTERV
                     QIIGDDERAVELARLTIQALLVLVGRGMVINTSDVVTALSMADSDRLDQFVALYEEEI
                     IKDFYSKPIRVKTLGQKAYVDSIKHHDVVFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKEQTTRLMERDIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFQSKMIVNGDISQIDLPRHITSG
                     LIDAAQKLQAIKQIDFVHFSAKDVVRHPVVAEIIKAYETVGSKAESLKSSPNQLQHQT
                     KAPDRPKTETGQSTSGLTTYEVIGELPKEDKS"
     gene            complement(14877..15092)
                     /locus_tag="TV191_000563"
     CDS             complement(14877..15092)
                     /locus_tag="TV191_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEL1507101.1"
                     /translation="MRKAFYTWLMAQRNSTSNKPAALLADLVFEDPTFPKHTDDFETI
                     SRYLEEEASFSFNLGQFDQIWEDYLSH"
     gene            complement(15089..15598)
                     /gene="msrA"
                     /locus_tag="TV191_000564"
     CDS             complement(15089..15598)
                     /gene="msrA"
                     /locus_tag="TV191_000564"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HEL1507102.1"
                     /translation="MERAIFAGGCFWCMVQPFEEQAGILSVRSGYTGGHVHNPSYEQV
                     CSKTTGHTEAVEIIFDPSLISYSDLVELYWAQTDPTDAFGQFEDRGDNYRPVIYYTDE
                     RQREIAERSKQTLQASGRFDQPIVTSIEPAEPFYLAEDYHQGFYQKNPERYAQSSAIR
                     HQFLEEHWQ"
     gene            complement(15936..16793)
                     /gene="cvfB"
                     /locus_tag="TV191_000565"
     CDS             complement(15936..16793)
                     /gene="cvfB"
                     /locus_tag="TV191_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEL1507103.1"
                     /translation="MNHLLATVITGLVKEENSQFYLVQKEGLSFALAKEEGSHRLGDM
                     VKGFVYTDMKQRLRLTTKPIDARRDHYGWGEVTTVRRDLGVFVDTGIPDKEIVVSLDV
                     LPELKDLWPKKGDRLYLKLVVDKKDRIWGLPAEPEIFQRLASPAYDNMQNQSLPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYTEPRLGQVLTARVIGFRERDRTLNLSLKPRSF
                     EMLENDAQMILTYLKSNGGYMTLNDKSSPEDIKATFGISKGQFKKALGGLMKANKIKQ
                     DVTGTELIS"
     gene            complement(16927..17484)
                     /gene="frr"
                     /locus_tag="TV191_000566"
     CDS             complement(16927..17484)
                     /gene="frr"
                     /locus_tag="TV191_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEL1507104.1"
                     /translation="MANAIIETAKERFTQSHHSLAREYASIRAGRANASLLDRIQVDY
                     YGAPTPLNQLASITVPEARVLLISPFDKSSIKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRKELAKEVKKVGETAKVSIRNIRRDAMDEAKKQEKAKEITEDELKALEKDI
                     QKATDEAVKEIDRMTADKEKELLSV"
     gene            complement(17521..18249)
                     /locus_tag="TV191_000567"
     CDS             complement(17521..18249)
                     /locus_tag="TV191_000567"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEL1507105.1"
                     /translation="MKPKYQRILIKLSGEALAGDKGVGIDITTVQSIAKEIAEVHNSG
                     VEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQHYGVDTRVQT
                     AIPMQNVAEPYIRGRALRHLEKGRIVVFGAGIGSPYFSTDTTAALRAAEIEADAILMA
                     KNGVDGVYNADPRKDANAVKFDELTHGEVIKRGLKIMDATASTLSMDNDIDLVVFNMN
                     EAGNIKRVVFGEHIGTTVSNKACD"
     gene            complement(18548..19228)
                     /locus_tag="TV191_000568"
     CDS             complement(18548..19228)
                     /locus_tag="TV191_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1507106.1"
                     /translation="MIEFRHVYKSFHQKPVLTDCHFQMEKGESLGIMGESGSGKTTLA
                     RLIIGLEQPTAGQVLFHGQPYSVKVCGPRILLVFQDALRSVNPLFTIQEILTEALSKD
                     FALEEVVQILAAVGLDATHLGKKARELSGGQLQRVCIARALLLRPEVIIFDEALSGLD
                     PITQGQLLDLLYELKQEYQLTYIFIAHDANICQAICHRVLLLEQGRLVAVRDKEPQTS
                     CGGIGLDN"
     gene            complement(19215..20003)
                     /locus_tag="TV191_000569"
     CDS             complement(19215..20003)
                     /locus_tag="TV191_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1507107.1"
                     /translation="MERLIVNDLSAYNGSDVLLSKLNLELPLGSSLVIVGRSGSGKTL
                     LTKLLIGQCPSNVQMTGRITCQDMRLDQLDAKQWQSIRGRHMAYMVQNPMAMFNPFQT
                     IEAHLLETIRSHERLSKRACLKRALPFMRELYLEQPEELLRKYPFELSGGMLQRVMLA
                     ILLCLDPQIIILDEPTSALDDANRSNIIRMLKLLQDKGKTIITVTHDYQLAQTLGGQL
                     LVMSKGKIIEQGSVESIFHRPSQAATKELLLQNHYDRLIRYDRV"
     gene            complement(19991..20797)
                     /locus_tag="TV191_000570"
     CDS             complement(19991..20797)
                     /locus_tag="TV191_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1507108.1"
                     /translation="MPKYVIGSAVMLLLLFICVLFAPYLAPFDPHAVDVASKLMPPSQ
                     QHLLGTDQLGRDVLSRLLYGAKYSLLLAVTISLLELSIGAVVGLVVGWYQGRLEAAFL
                     WLADVVSAFPSFLLSLATMGILGQGIGNMILAIVLVEWLYYARLMVTMVKSAKAEPYV
                     ISAQTMGLSVRHILKKHILPFVYRPIVVLALMNIGNIILMISSFSFLGIGVQPNVTEW
                     GMMLHDARSYFRTALWLMMSPGLAILVTVLAFNSLGDYADAKGWRKTWNG"
     gene            complement(20782..21723)
                     /locus_tag="TV191_000571"
     CDS             complement(20782..21723)
                     /locus_tag="TV191_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1507109.1"
                     /translation="MMKKLISTFGALLMISIVTFVLVKLSSANPAEQYLRLSKISITP
                     EALHNARLYLGLDKPLWEQYVTWLSDILVGNFGTSYVLKVPVLPLVVERFLATLMLSL
                     TSFLLVLVIAFPLGVGSGLFEHSLFDRLVRLFSFVAVSMPSFWLGYLLIIAFSVKLNL
                     LPVSGKAGASSLILPSITLSFSLIGQYTALIRKAISEQLTSLHVENARLRGVKTYYIV
                     KHHLIRNAFPAIATGLSLTFVYLMTGSIIVEDIFSWNGIGSLFVMSLKAADIPVIQAC
                     MLLFGALFLLHHVITQELVSFIDPRLRKTKEEACPNT"
     gene            complement(21801..23423)
                     /gene="nikA"
                     /locus_tag="TV191_000572"
     CDS             complement(21801..23423)
                     /gene="nikA"
                     /locus_tag="TV191_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel ABC transporter, nickel/metallophore
                     periplasmic binding protein"
                     /protein_id="HEL1507110.1"
                     /translation="MKTKLNVLLLFFFALLLTACQNAKQASYRTDQLRIAWGEDFGDV
                     NPHRYNPDQFVIQDMVYEGLVRYGDKGNIEPALAESWTISPDGKTYTFNLRQAKFSDG
                     SDFNAQNVKRNFDSIFSEQNKGNHNWFHFTNQLDSYKALDDHTFEIKLKEAYSATLYD
                     LSMIRPIRFLADAGFPDGDDTNKHNVKKPIGTGQWVVKEKKANEYITFTRHESYWGEK
                     PKLKEVTIKIMPDAETRALAFEAGDIDLIYGNGLISLDTFVQYAKDKKYVTDVSQPMS
                     TRLLLLNAKQSVFQDKRVRQAMNHAVDKKAIAKHTFRGTETAADTIFSKTTPHADAGL
                     VPYEYNLQKAKDMLTAAGWKENQEGIREKDGQQLRLQVPYISTKATDKDLVEYFQGEW
                     KKLGIDVVLTAMEEDDYWANAKTGQFDMMLTYSWGAPWDPHAWMTALTAKADHGHPEN
                     IALESLPSKAEIDRLIKSVLIEPDGDKVDKGYKQVLSLLHDEAVYIPLTYQSVVSVYR
                     KGDFKTMRFAPEENALPLRYIEKSAADKAVKN"
     gene            23925..25565
                     /locus_tag="TV191_000573"
     CDS             23925..25565
                     /locus_tag="TV191_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1507111.1"
                     /translation="MKKTMKKMLAASTLCIIMSGSFISGSARVLAEEYYGWNDVTGSK
                     SPFPLYVTPKNGDKNIKVQQTVVYCFNRDGQWPENWEKRIYESPDKVPHKLPEYNKKS
                     GSDNLFQLLNPKIKIKNPMAALLAVLEDGYPTSSSSGVNQRTTQLAIWHFTDGLSNLA
                     QFHLTPEETSAYNKLIEKGTNASNQSENKLLNKTLDIYSYIDGTGDKKHNYQHLLGST
                     PIPIDNSKENKCQCTKVDLMRTGDGVKIIVYVDNNGNNRYDNGDKMLKEETIKHGQRG
                     PAGESGKPGPKGDRGETGARGPAGPQGKPGKQGPRGDKGETGERGPQGEKGEPGTPGP
                     KGEDGKDGAPGRDGQPGPKGEKGDPGKDGQDGKPGEKGEPGIPGPKGEDGKDGAPGRD
                     GQPGPKGEKGDPGKDGQDGKPGKKGDPGRDGKDGEKGERGEQGPKGERGEQGPQGERG
                     EQGPRGENHTPTPDPMPEPAPKPESKPEPKPTPQPEVKPLPETKPQKPTKPSAMASQP
                     SSKALPKTNDTSGLMTVLGTGLLSLLGLGFLAKRKRKQ"
     gene            complement(25809..26498)
                     /gene="rplA"
                     /locus_tag="TV191_000574"
     CDS             complement(25809..26498)
                     /gene="rplA"
                     /locus_tag="TV191_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004232886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEL1507112.1"
                     /translation="MAKKSKQMRAALEKVDSTKAYSVEEAVALAKETNFAKFDASVEV
                     AYNLNIDVRKADQQIRGAMVLPNGTGKTQRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINGGWLDFDVVIATPDMMAIVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADKAGNVQAIIGKVSFDADKLVENFKAFHEVMVKAKPATAKGTYMTNVSITTTQ
                     GVGIKVDPSSF"
     gene            complement(26604..27029)
                     /gene="rplK"
                     /locus_tag="TV191_000575"
     CDS             complement(26604..27029)
                     /gene="rplK"
                     /locus_tag="TV191_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEL1507113.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFDFITKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANIEAAMRMIEGTARSMGFTVTD"
     gene            27265..28062
                     /locus_tag="TV191_000576"
     CDS             27265..28062
                     /locus_tag="TV191_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1507114.1"
                     /translation="MHKKVTIKDVAREAGVSVATVSYVINNREDQKISPETRNKVLQM
                     INLLNYRPNQAAKSLVTQKRQLIALYYKEHSSVLKRAEQLHFITQLSAFLYTKHYHLI
                     CLNQEYIGKYDVADVILTLEVTKEEFYKIGNSNFVPLIAIDSIIDDPLFFQINSDPHL
                     LFNKASAYFAGEPFELVSLPIQNQEITQGLAQQFDNICWIHSICDIESVSKGNILVID
                     DTVNHILSKHKNKLYLPSISEAKLLKLFQAIEWASKREAINNHNILV"
     gene            28217..28567
                     /locus_tag="TV191_000577"
     CDS             28217..28567
                     /locus_tag="TV191_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEL1507115.1"
                     /translation="MIIYKLTALAFIILTPLFSMIMISLLRLGRRGLKFPDLALPLFV
                     FEIVIVSGKFFTHHLLPYYLIVMSLLAIVMALLLIIRIQQFSYRRFFKLFWRVGFLVT
                     LLFYLMLVGLIFIV"
     gene            complement(28896..>29407)
                     /locus_tag="TV191_000578"
     CDS             complement(28896..>29407)
                     /locus_tag="TV191_000578"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507116.1"
                     /translation="EKLQTKRIFFFSVVALTILTISDQKVNASQYRWRQYYYRMSPTE
                     RELKKEKEVLRNFIATIKLSYSEANEMEAKVYGADSFSKLRAIKEELQSLKSRYFKIS
                     NKVEIVSSLIDEHFPEGHSRNIMKKYRLEFLDRLMGIQYDVGLNKDRALDDLSERIIM
                     TRKKLWYIQ"
BASE COUNT         9087 a         6796 c         5227 g         8297 t
ORIGIN      
        1 taatagacca atggttttcc attgatctac tgtgtattaa aaaaacaggc tagttaacat
       61 aataatgctc tcggccacca acgtaccacc aaaaactgta ataaaggttt gtttaaagcc
      121 atttttatgg ctgagaccag taaggctcaa gaaggttaaa aagacgccag actggggtac
      181 aatggtcaaa atattagagg caacagctgc cacacgatga atgatctcag gtgaaacgcc
      241 tgcatctaaa taatattgag caaaatttgg cattacgatc cctaacgctc ctgaagacga
      301 acctgtaata gctgccatag ccgaagtcag gacagtcaag ctgatcacag gtggcccagg
      361 aatattcaaa atgatgtctg agaatacgcc aaaaccagat gctgctgtaa caacagaacc
      421 aaaggctact gcagaggctg tcgcaaagat tggaccaacc gcaccgctag caccaatgct
      481 gagggtcgca attttcttat caatgtactt gttaaataaa acgatagctg aaataattcc
      541 tgtcaagagg gccacataaa tgatattttt cttaacgaat tcgtccccta gcagactacc
      601 tatgatggca ataacaatca agagtatcaa aggcaagatg ctgactacaa atggtggtaa
      661 aaccctttca gttgtatctt catttgtttg actagtatag gtcgcatagt tttcgccaac
      721 ttctaaactc ttagtcaaac aacgcttcat atagaaaaga ccaaaggcga tacagccaac
      781 actccctaaa atacttggca ccaaggctgc ggttagagac gtgttaagat attgtatagg
      841 gataacgttt tgaatcgctg gtgtaccagg taagatcgtc atagtaaagg ttgcaatccc
      901 caaccaaagt ggtacttgaa ttaagttcca tgctaagtcc atctttttaa agagagagcg
      961 tgccaagggt agaacagcaa acatgaccac aaagagacta ataccaccat aagtcaaaat
     1021 agcactgatg ataaaaatag ccaccaagat acggtaaggg ttttgataac ctactttttt
     1081 caagataaat tcagcaatgg aaactgttgc accactgact tccatcaatt tagctaaaat
     1141 agaccccaac aagaagatag caaagtagct catgatatag ccacccagcg cacccatata
     1201 gttatttggt tccttaccca agagtgactc aactagtggc atactattta gaaggacgac
     1261 caaaatcgtt gccataggag ccgcaatggt aatatgaatt tcctttagag aaaaataaac
     1321 gatggcaata atgcccagca agaccccaat tggtcctaaa aattccatag tgtttctcct
     1381 ctcacattca gaaggagcaa gagatagaga aatgtcactc tatctccaat cctcttattt
     1441 acactgaacg gacagctctt actgagcagt gtagccacca tccaagataa ccggttgtcc
     1501 agtaattccc tttgccttat cacttgctag gaaggagaca taatctgcaa tttcttgtac
     1561 gtcaatcaaa cgtttttgcg gtaccaacgg gtacaacact tcttccaata cattttcaag
     1621 cggaatctta cgtgtcttag agaggtcttc aaattggcca cgaacgagtg gtgtgtccac
     1681 atagcctgga cagatagcgt tgactgtgat acctaattct gcggcttcaa gcgctgcaac
     1741 ctttgtcaag ccaatcaaac cgtgttttgc tgaattgtaa gccgcttttc cggcaaaacc
     1801 aatgacacca ttgatagaag ccatattaat gacacgacca aagccttgct ttttcatagt
     1861 tggaaaagcg cgcttaatag cgataaatgg cgctgtcaac atgaccttca acataaattc
     1921 atattttgct gttggaaaat cttcaatcat ggcaacatgc tgcaaacctg cgttgttgac
     1981 caaaatatcc aaacgaccat gcttttcaac tgtataatca atcgctttat tgatcgcttc
     2041 ttcatttgtc acatcacaca aaacagaatc agccgcccag ccttttgtgg tatactcatc
     2101 aacaacagca tctaattttt cttgattgat atctgaaaag acaacgattt tgccctcttt
     2161 taagaatgtt tcaccaattt gtttaccaat accgcttgct gcacctgtta cgaatactac
     2221 ttgtttagac atatttattt cctcactttt tttaaatatt gttttctatc agttatgata
     2281 aattaatctt gcttcggtgg cttcttgaac ttcttcaaag gtataatctg gatgaatttc
     2341 ttctactgcg attccctctg gagtgactgt gaagacaccc atttctgtga caatcttgtc
     2401 aacaactcct gctgctgtca atggcaatga acactccttc aagattttcc atttgccttt
     2461 attggtatgc tccatagcaa caatgacttt tttagcaccg actagtaaat ccatggcacc
     2521 gcccattcct ggaaccattt tccctggaat aagatagttt gcgatgtttc ctttttcatc
     2581 aatttgcaaa gcgccaagaa ctgttgcatc gacgtggcca ccacgaatga tcccaaatga
     2641 agtggtgcta tcaaaaaatg ctccgcctgg tacgatgcca accggctgac cacctgcatt
     2701 aactatagtt ggatcaatgt catcgcctac tttatctaag ccgacaaaac cattctcaga
     2761 ctgcagcatg atagtcacac cttctggtaa aaatctagct accttggttg gcaagccaat
     2821 ccccaaattg accagggaat tatttggaag ctcgagtgcc acacgtttag caattcgttc
     2881 ttgaatttct tctttgctta attctttcac cataacgctc attctccttc cactagataa
     2941 ttgacaaata tgcctggtgt ttgaactgca atgggttcaa tgtctccaag cgagacaatt
     3001 tcacgcgctt caacgatggt cacttttgca tttgctgcca taacctggtt gaaattattt
     3061 tcagagccct tgtagcatag gtttcctaat tcatcagcct tatctgcaaa aattaaagcg
     3121 acgtcagctt tcaatggtaa ttctaacaga taatccttgt cattgacctg taatttttgc
     3181 ttaccttcct ctaccaaggt accgatgcct gtcggagtca agaagccacc cagtccgtaa
     3241 gctcctgctc ggattctttc agccaaggtt ccttgtggca ctaagtcaat cactgtttca
     3301 ccggctgtca tttggcggcc tgcttctttg ttcaagccaa tatgagaagc gataattttc
     3361 cgaaaccgat gttgtgctac cattttaccg acacccttgt ctgggaagcc tgcatcgtta
     3421 caaataagag ttaaatttgt aactcctttt gctaccaaag cgtcaatcag gcgctctgga
     3481 ctcccgttag tcataaaacc accaaccatg atggtgtcgc catcctttac aaggttaaca
     3541 gcttcttcta tgctaattcg tttattcatg aaaccatctc cttttatttt tcaatcaata
     3601 cagacgtccc ttgaccgcca ccgatacaga gtgttgccaa tcctttatgt gcctgacgct
     3661 tttccatctc gtgcaatagt gtgaccaaga tacgcgcacc gctagcaccg atcggatgac
     3721 caagagcaat agcaccacca ttgacattga cgatagccgc attaagacca agctcatcta
     3781 caacactgat agcttgtgag gcaaaggctt cattggcctc caccaaatcc aagtcttcaa
     3841 ttgtccaacc aaccttagca agggccttct gagtggaagg aattggccca gtacccatga
     3901 cctctggtgc tacaccagca cttgcataac ctttaatggc tcccagaatt ggaagaccaa
     3961 gttcttcagc tttgtcacga ctcatgagaa ggacagctgc cgcaccgtca ttaattcctg
     4021 aagcgtttcc tgcagtaaca gttcctgaac catctcggac aaaggccgga caaagggctg
     4081 ttaatttttc aagggttgtt ccagctttaa tgtactcatc ttctgccacc aaaattggat
     4141 cacctttacg ttgcggtact ggcactggaa taatctcatc tacaaagcga ccagcggcct
     4201 gcgcagcagc agctttttcc tgactagcca aagcaaatat atcttgagct ttacggctaa
     4261 tcccatagtt ttttgcgata ttttctgctg taattcccat gtggtaatca tgaaaggcat
     4321 ctgtcaaacc atcattgacc atagtatcaa tgatttttcc atcgcctaag cgaccacccc
     4381 aacggtaatc tttgagcaca tagctggctt ggctcatatt ttctgtccca cctgcaataa
     4441 tgatatctga atcaccacag acgatacttt gtgctgctaa ctcgatggat ttgagaccag
     4501 aaccacagac catatccaca gtgaaggcag gtttgtcgtt tggaatacct gcagttatcc
     4561 ctacctgtct agcaacattt tgaccgagtc ctgcatggag gacatttccg aaaatgacct
     4621 cgtcaatttg ttcaggcttc acacctgatt tctctagtaa tgcttctaca accacttttc
     4681 ctaattgaac agccgagaca gatttaaagg ctccaccaaa tgaaccaatg ggtgtcctaa
     4741 cagctgtagt gataacaact tctttaacca acatgcgatt ctccaatcta tttgttatag
     4801 aaagcgcttt ctgtttttgt gaatttattt tatcactact aaaagcgttt gcaaaattcg
     4861 atttttttat atgactataa aaaattttta ttatttttta ttgacagcta taaaaattat
     4921 tattagtatg aagaaaaaga catctgaaat gaaagaagag gcaatatgga tattaaacat
     4981 ttacgctttt tcattgctat tgtagaaaat aattttaacc tgagccgtac cgctcaacag
     5041 ctttatattt cccagcctac cctcagtatt atgattaatg attttgaaga aaagcagggc
     5101 attaagctct tcaataaaaa atacaataaa atcctcggct taaccatgac aggcaagcaa
     5161 ttttatgagg attctttgga ggttatccgc aaatatgaca agatgcacca aaatctcttt
     5221 tccaccaatc aaaagttgga cggtaatatc actatcggca ttcctccatt aattctgtca
     5281 attgtttttt caaaaatcat gccagaaatt attctagaaa atcccaatat ccactttaat
     5341 attaaggagt atggtgctaa tcggctacgt caggaattga ttttagagaa tgtggatatc
     5401 gccattcttc tgcatcctga acgaattgct gcaaacacca ttgattcttt ccaaatccaa
     5461 gaatctgagc tctgtgcatt tgtctccaag aaccaccatt tggccaataa aaaaatcctg
     5521 acttggatag aactccacaa tgaaaaacta gctatatttg ataaaacctt catgattcac
     5581 catctcatca aggaaaaatg taagtatact gacattaacc cccaaatcat tctggaatca
     5641 gcttcttggg actttctgat caattctact cgtatcaacc ctcaactaat gacgattatt
     5701 ccaaaaccaa cggtagatag ctatggtttt caggatattg tggctattcc tatggagaat
     5761 cctattcctt ggaaagtcat ggttagtcgt ctcaaaaaag atcattattc caccatagaa
     5821 gaatacattt tcaacaaaat gcttgaaaaa tttcatgtaa tcgaatagag actaacaagt
     5881 gatccctttc acatgactgc acgtgccctt cgacatatgg cacctcaact aacccttagc
     5941 gcatatggaa acagctcaat tctttttgaa ggataaaact aaagaggctt gacgatccat
     6001 actaactcag acccaatatt attatcaaga tcctaaatat taacacaact catttataac
     6061 aattaactta caaaaaatgg tctactcctt tgaggcgtga cagcaatact gcaatttata
     6121 aaaaatgact gtcaagacaa tatctctgaa ctcagtcact gtttctcaaa aatcactcac
     6181 atctaatgga gtactatcaa gaaaaagtta tttttaaaat catcaataac ctatctaaat
     6241 tttctaaaca atgccatata aaaagagctg gagtcaccaa gctctaattg atttttacat
     6301 gatgctctat aacaatatcg tttaaagatc attctttttt actagtatgt tgatcacatt
     6361 ttctaaaagc cagaaagaga cttgaatacc gagtcccttt tctttttatc tataaacagc
     6421 cttaaagaag cccagacagg ctgcggtaat tttcttaaca tgagcttcta ctatttctct
     6481 tgttaagccc tgctcacttg atgattcgtt atttttacca cctgaagact ctcctctaca
     6541 taggctactt tgtcatctag ttcctgcttc ttaacgatat atcatcgtct caattgatgc
     6601 cacttccctt atcatcttag aaaaaagcta atttctatac ctttaggtgt tctagatcac
     6661 aaaatagctt tctcaatcct atctaccttg caagaattca ttgaatgccc ttaacttttg
     6721 cagtaacgac aataaaaata gtttagataa cgatgctatt gatgttactg acttaccctc
     6781 tttattgata agtatgctaa atataagcaa agaaatgcaa aagctaatct aatcatgaca
     6841 ataactaatc catcaaccca aaaactgcca aaaaagccgt cataagcaag cttaagcatt
     6901 atgtttggtg tactcgcagt tgatacagat aaaatactca acaccttatg aggtattcct
     6961 gcttggaaaa tatccataag aaaacttggt acaaaaacac tagccgcaga caaggcaaaa
     7021 cctgtcaatg gagacttaac cttacttgaa ataaggatag tgatagccgt aatcaggata
     7081 agcccaataa actgataggt gactagattg ataaatgttc ccaaaagagt cattttttct
     7141 ggaaaagcca ttatattcac attgctgtta atccaataca gattgagttg aacactcgtg
     7201 tcccaaccac ttaatccaaa ataccaaaca aagaccgcta atattatggc gtaaaaagta
     7261 acaaacactg aggtgcttat caagtaacta cttattatct tggctatcgt aagtttatta
     7321 cgaccatacc tagttgtcaa taaaatagga ttcatatttt tagcagtatc accggaaaaa
     7381 acaggagcga tgaagtaaac agacaaaaga agaagaagga tataagcact atttatgacc
     7441 agaaaaagct gattccaggg tgcaaaatta cccaacttca gctctttaaa gggaagataa
     7501 gagccaagag ccgtttgaga ttttggggtg atcttactga aatcaatagt ctcttctttt
     7561 ttcaaattaa aataataatc tctaaatttt ggatcaaaat ggctagttac atagtagcca
     7621 tacacattga agacaggatt ttttgagctg ccacctagag tataatcttt gattgttcta
     7681 attaataact cattggacaa ttgaccggta tgttcttccg caaatcgctt gtttatctca
     7741 acagcatctc ttccatgaat tttatctatc gaagaaccac tgatttgtcc attaaaaaag
     7801 ttgatataaa ataacccaaa gattgctaat aagctaacaa taaacattcc caaaactgat
     7861 ttggttcgga tcagtttttt taattcaaat ggtaagagag ctttcataac acctgttcct
     7921 ctctaaagtg ataaatgtat aagtcttcta aggttggtga cactagttga gccaactgat
     7981 ttggtttctc atcactaacc acacgaaaaa cacgactaga tgaaactagt ttctcattga
     8041 ctacagcata ctgaccatgc cttggtaacg gcgaaccatc agagacagaa aactcccaga
     8101 ccttgccaaa gatggttttc aacaattctt gactactact cttatggata aattgaccat
     8161 tttttaaaat gataatctcc ttagcaatag cctcaacatc agagacaata tgagttgata
     8221 agataataat tttgttggcc gacaattcgc taataatatt gcgaaacttc accctttctt
     8281 ttgggtctaa tccaactgtc ggctcatcta aaatcaagat tttagggtca ttgagtaagg
     8341 cctgggcaat accgagacgt tgcttcatac caccagaata agaggcaatc cgcttcagac
     8401 ggacatcata tagatccaca agttttaaca attcatccgt ttcttgcttg gctttatgtt
     8461 taggtattcc ttttaaggct gccatataaa gaagaaagtc tcgaccagaa aaacgaccat
     8521 aataactaaa ctgttgaggc aaaaaaccaa tatgctgata aaattcctct gattgaggtt
     8581 tgtgatccag taaaatctct ccttcatcag gagtcgtaaa atgactaatg agattgagca
     8641 aggtcgtttt ccccgtccca ttagccccta aaagtccgta aaggcctggg gtgaattgag
     8701 tagtaatcct tcgcaaaata tttttcgatc cgtagctctt actcaattga tttaattcta
     8761 ataacataga accctcctta aatgagtcta ctgagcacct gtaactcagt actcagtaga
     8821 cttctcctgt acgaaatcct gctgtctgta acctttatta ttctcgtagc ataatcaaat
     8881 ccagagattt tcgattcatt aatgaaatat tgacgatgac acctttttaa tttcccagca
     8941 ctttctccct caatctgtct cagtgacgta gctgccccaa attccccttt tagggtaaca
     9001 aatactactg tgtgaggctt agatgaatgt gttgtcacat cataggtttc agagattggt
     9061 aatttaacaa ctgacctatt cttatataaa ataacatatt tcattgacgt cctccttctc
     9121 tatttatatc ttaatacaag tacaagcatt gagacggtaa agtctcaaat ggtatctatc
     9181 atatcctgaa tggtatcaca gtagctgttt aagatgtcat agaggcattt gagaaatgta
     9241 acctgttttc ctttcgtttt ttgatcatat gatattgtat tagttcggag aaccatggta
     9301 atcattcaaa tcttacataa acctctcttg ggatatggta ttagcgtcta tattaattac
     9361 tacttcaaca gacacctttt taaagctgct aaaattgtca gtggcaaaca aataggctat
     9421 aggtataaat ctcacactta ttttatcata aaatcattct ttttatcatc taatcaaatg
     9481 tacaagcact ttaaagttat tctcatgact ctattattct tattggaagc catattaatt
     9541 acgacgacat tttcagaaat cattatcgtg tgtttggtat catcgacaca accgctaata
     9601 aatcgtttaa atgtatccaa aaccaaattc atgattacct gttcaaagaa taaccagagg
     9661 gcttactgat tgctttaaca aatatttcta gtcttctcat tttgtactca tataaactca
     9721 tctactctat taaaaattgc tgtgaacaga aaaaccttct caacctgttt cagttttata
     9781 gccgtagtta gtttaaagtg aaaccaccct gcattttcta tacctaaatc caattgactt
     9841 gctttttcag catcaacagt catgctatcc ataagataac acaccacgat gtgttgtgat
     9901 tattgttctt ctatatttag ccttacctcc tgaaaacaaa aaaagagaac accttttaaa
     9961 tgttctcata taagcaatct tatatattaa atgaggattc gatctaatga caagacagcc
    10021 ttattgctac caataatgca gcttaccaaa caagggcaat cagtataagg gttgctaacc
    10081 agctctgctg acatagcctg ctttgagcga tcaatactcc ttctgattat agccaaagtc
    10141 agctaaatca agctttttgt cacgccagtt tttcttaacc ttgacccagg tctccagata
    10201 gaccttatcg cctagcatta gctcaatatc acgccttgcc agcttaccga tttttttgag
    10261 catggcgcct tgttttccaa taataatgcc tttttggctg tcacgctcta ccatgatggt
    10321 aactcggata tgcaccttgt cagtcacctc atcacgcttc atcgaatcga ccacaacagc
    10381 aactgaatga ggcacctcct gctgtgtcaa gtgaagcacc ttttcacgaa ccatctcaga
    10441 aacaagaaag cgctctgggt gatcagtgat ttgatcctct gggaaatact ggaagccctc
    10501 ttcaaggtta tcctttaaga gctgaacgag cgtttcgacg ttgtttcctt gaagtgctga
    10561 aataggaaca atttccttaa agtccatctg actacggaaa tcatcaatct gctccaataa
    10621 ttggtctggg tgaaccttgt caattttgtt gatcaccaaa ataaccggaa tacgagcagc
    10681 cttgaggcgt tcgataatca tatcatcacc cttaccacgc ttttcatcag caggcaccat
    10741 aaaaagaacc gtctcaacct cacgcagggt actataggct gattccacca taaaatcacc
    10801 taaggctgtc ttaggcttat gaatgcctgg cgtgtcaata aaaacaattt gctctgtctc
    10861 tgtggtatag attcccataa ttttattacg ggttgtctgc gccttatcgc tcataacggc
    10921 gattttttgt cccatgacat gattcaaaaa cgttgatttg ccgacatttg gtcggccaag
    10981 aatggcaaca aagcctgatt taaacataag ctactaaggg cctaaaggat cagtcaaggt
    11041 aagaatcaag cagcaggcta ttcacctgat tgctttccta aagcttatac tcctttcctg
    11101 cgctgcacta tcgcacagga tagcccattt cctttcattt ttttaatggc ataacattcg
    11161 ccaaattttg ggaacaaaga taatcagccc cgtcaaaaca gcatagcctg aaatgaccag
    11221 gacagcacct gcagccatat ccttggcatg cttagccagc atggagaaat ggtaatcact
    11281 tgccaagtca accacatttt caatagctga attgacaatc tctaaggtaa tcaccaaaaa
    11341 aatagccagc aataaaaaca gccattctat agcagaaata ccaaaaacaa tcccagccaa
    11401 agaggctaac agggctgaca aaagatgact tcttaggtta cgctcctcct taaaggctgt
    11461 cagaacccct gtcaaagcaa attctaagct ggcaattact gttctgtttt tccatttgcg
    11521 tttattattg tcttgtgagg ccataagcag tcaaaatctc ttcctgtaac gtaaacatct
    11581 ctttttcttc ctcaggagtg taatgatcat aaccattaat atgcaaaaaa ccatgaacag
    11641 ccaagaagcc catctcacgc tcaaaggaat gcccataggc ttctgcctgc tcatgggctt
    11701 tgtcaacaga aataaacagc tccccaatat aagcatcaaa ctcctgtatc atacctgcca
    11761 agtcaggatc aagctccaaa tcctcttggc taaaggcgat cggaagctct ggcttgtact
    11821 ccagagaaat cacatcagtc ggacgatcag tatcacgata ttcaagattc aaggcgtggc
    11881 ttctatcatt ggtcacaaag gtaaccgcca tttccttgtc ctctttacca attgttttgg
    11941 cagcaaaatt gagcaaatca atggtttgct ccatcatctc ttgagaaacc tgcttagttt
    12001 catcaatcat ctctatatac atcattatat gaagaggtcc tagcaagaca ggtccaaaca
    12061 aacaccacac tgctaggtca aaaagcttga tacctcttat cctttcaaca tcatttcagt
    12121 actttctttc cattatacca caagaaaaaa gaaaaagcag gcattagtct agcctgctcc
    12181 aaaagaagcc ggaataatga caagatcgtt gataccccag cagctgctgt ttctggaata
    12241 cccagagcct gctgcgcaga atacagtcct cttagatagc tgggactcct aggattacaa
    12301 tagtagataa gcctttagac cacttccatc gcctaaaaac taatcctaaa cggctttccc
    12361 ttagatacca ctagctgctc tcaaagctat tgtggaggta acgatctggc ttattggctg
    12421 acgccagtga tttctgcttg tcataatctt ctttggttaa ataatagtgc agcactgtca
    12481 caaaacggtt ggaatcaagg tgatcacgct tagcatatgg ctcttcatgt gaaaagcaca
    12541 tgccgctttt agccataaca cgtcccaaag ccggattggc tttatcatgc ttagcaatca
    12601 cacaattcat gcctaaagct tcaaaacaca agaccagtac agccttgaca gcctctgtcg
    12661 catagcctct tccccagtga tgcttatgaa gacaatagcc aatctcagct ctacctaaat
    12721 ccagctgtat atgatgaaga tcaagcgtcc caataaagtc tcctgtttcc tttaacacaa
    12781 tcccccaccg tccaagtgga ctagccagat agacagaagc aatgacttga cgggtctcct
    12841 caattgtctg attggctgga aagctatacc tgacagtctc ttcatcagaa gcataatcaa
    12901 acatggcttt ggcatcatcc aaggtcactg gacgcaggca tagacgctct gtctcaagat
    12961 acctatgctc tgctagtttt tcaaaaaagc ttgccactac tactctccct ttcctaaaaa
    13021 tctaactcac ctaacagcat gactgcctgc cctagccgcg taaaatctgc ctcaccttat
    13081 cctttaaaac aggaaccagc tcctcttcaa accaagcatt tttagccaac caaagctgat
    13141 ttctaggaga tgggtgaaca aggggaaaat aatccggaag atagtcctca aaatgctgca
    13201 ccgtttcggt aagattgcgt ctacaacctt caccaaggta atattgctgg gcatactgtc
    13261 cgaccagcac caccaattca acctgaggca tcaaggccat taacggacca tgccacttgg
    13321 cagcaaagcc ctttcgcggt ggtaaatcac ctgattttcc cttaccggga taataaaaat
    13381 ccataggaag aacgccaaac aagcccgact gataaaaggt cctgtcatca acacccagcc
    13441 aagctctcaa gcgaactccg ctacgatcat tccagtacag acgcgtctcc tgagctacaa
    13501 taccaggcgc ctgaccaaca atgactatcc gagcggtctg aggagctgca taaagtggtt
    13561 cgataccttt tttggtatag tcacgattgg caggatcagc cataatcgct tgcaatagct
    13621 ctgtcatgat accctcactt tcataaaagg ctcttcaggt gaagagctct tttttacgat
    13681 ttgtcttctt taggcagctc tccaatgacc tcataggttg ttaagcctga cgtagactga
    13741 cccgtctctg ttttaggccg atctggagcc ttagtctgat gttgcagctg attagggctg
    13801 ctttttaatg actctgcttt tgaacctaca gtttcatagg ccttaataat ctcagcaaca
    13861 acagggtgac gcaccacgtc cttggctgaa aaatgcacaa aatcaatctg cttgatggcc
    13921 tgcaattttt gagctgcatc aatcaagcct gatgtgatat gacgcggcaa atcaatctga
    13981 ctaatgtccc cattaacaat cattttagac tgaaaaccaa gtctggttaa aaacatcttc
    14041 atctgcatga tggtcgtgtt ttgcgcctca tctaaaatca caaaggcatc atctaaggtc
    14101 cgaccacgca tataagccaa gggagcaatc tcaataatat cacgctccat taaccgagta
    14161 gtctgctctt taccaagaat ctgataaagg gcatcgtaga ctggtctaag gtaaggatca
    14221 accttttcct tcaaatcccc tggtaaaaag cctaagcttt ctcctgcttc aacagctggg
    14281 cgtgtgagaa tgatccgctt aacctgacca cgctttaaag cagtaactgc tagcgtaact
    14341 gctaaaaagg tctttcctgt tccagccgga ccaataccaa ataccacatc atgatgcttg
    14401 atactatcaa cataggcctt ttgccctagc gtcttaacac gaattggctt gctataaaag
    14461 tccttgataa tctcttcctc ataaagagca acaaattgat caagcctatc tgaatccgcc
    14521 atagacagcg cagtcaccac atcagaggta ttgataacca tgccacgccc caccaaaact
    14581 aaaagggctt gtatcgtcaa acgcgctagc tcaacagccc gctcatcatc accaataatc
    14641 tgaactcgct cagttctagc atgaatcaca acattgaggt gagattctat catcttcaaa
    14701 tggcgctcat tgctaccaaa aagagctaac agatcatctg ggtgattcaa gctaatgtca
    14761 gtcgaataat gcaaatttgt cttccttttc catctataag taactctatt ataacaaatt
    14821 ttgctataaa tcgggaataa gacccagctt taaagcctaa aagagctagc ctatggctag
    14881 tggctaaggt aatcctccca aatctggtca aactgcccca gattgaatga aaagctcgct
    14941 tcctcttcaa ggtaacgact gatggtctca aaatcatctg tatgctttgg aaaggtcggg
    15001 tcctcaaaaa ccaaatcagc taataaagca gcaggcttat tagatgtcga gttgcgctga
    15061 gccatcagcc aagtgtaaaa cgcctttctc attgccaatg ctcctccaaa aattgatgac
    15121 gaatagcact actttgtgca taacgctctg gattcttttg ataaaagccc tgatgatagt
    15181 cctctgctag ataaaaaggc tctgccggtt caatgcttgt cacaatgggc tggtcaaagc
    15241 gccctgaggc ctgcagggtc tgcttggacc gctctgcaat ttcccgctgc cgctcatcag
    15301 tatagtaaat caccggccga tagttgtctc ctctatcctc aaattgccca aaggcatcgg
    15361 tcgggtctgt ctgagcccag taaagctcta ccaaatctga atagctgatc agactcggat
    15421 caaagataat ctcaacagct tcagtatggc ctgtcgtctt tgagcaaacc tgctcatagc
    15481 ttggattgtg aacatgccct cctgtgtagc cacttctcac tgataaaata cctgcctgct
    15541 cctcaaaagg ctgcaccata caccaaaaac agcctcctgc aaaaattgct ctttccatac
    15601 ctaatctcca ctttctttgt ccttacatta gtgattttca ttgtaacaaa aaaccttgcc
    15661 agaggcaaag cttaatataa aacaagtcac agactcaaag taacaagact cctcagccca
    15721 actagtgcct agcactaagc agtactgtca agcagccact actagatcaa gagggccaca
    15781 cagagctttt tcgacaacaa aaatgattgg cgctttaaaa caggctatca gctaagctcc
    15841 acactcaaaa taaggaagct agctatactg ataaaggata agtcttagca acaccgatcc
    15901 agcttatgat tataggctaa gagacagaca gctccctatg atatcagctc agttcctgtc
    15961 acgtcctgct tgatcttgtt agccttcatc aaaccaccta aggccttttt aaattgaccc
    16021 ttggaaatcc caaaggttgc cttgatatcc tctgggcttg acttatcatt aagagtcatg
    16081 tagccaccat tagacttgag ataggtcaga atcatctggg catcgttttc cagcatttca
    16141 aaggaacgcg gctttagcga aaggttgagg gtacggtcac gttctctaaa gccaatcacc
    16201 cgagcggtca aaacctgccc caaacgaggc tccgtataac gctcgctagg gtggataaag
    16261 cccagcatat tattttctgg caggtaaaca aaggtccctg atagcttcaa gcgatagaca
    16321 atagcaggca ggctttgatt ttgcatgtta tcataggctg gactagcaag cctttgaaat
    16381 atctctggct cagctggcaa accccagata cgatcttttt tgtcaaccac aagcttaaga
    16441 taaagcctgt ctcctttttt aggccaaaga tcctttagct ccggcaaaac atctaaggaa
    16501 accacaatct ccttatctgg aataccagta tcaacaaaca ccccaagatc acgacggaca
    16561 gtggtcacct cgccccagcc ataatgatca cgccttgcgt caataggctt cgtggtcaag
    16621 cgtagtcttt gcttcatatc tgtatagaca aagcccttaa ccatatctcc taatctatga
    16681 ctgccttcct ccttagctag agcaaagctc agcccctcct tttggacaag ataaaactga
    16741 ctattttctt cttttactaa gccagtgata actgttgcta ataaatgatt catatctttt
    16801 tgttctttct tttaaaaaat agggacaagt ccaaagcagc tgctttttag ccttgtcacc
    16861 tatcctgtta tgcctgatgt gtattaggtt acgcagctga tctagcttaa tgatcagata
    16921 agccgcttaa actgaaagta attccttttc tttgtcagca gtcattcggt caatctcttt
    16981 gacagcctca tctgttgctt tttgaatatc cttttccaag gcttttaact catcttcagt
    17041 gatttcctta gccttctcct gctttttagc ctcgtccata gcatcacgac gaatattgcg
    17101 aatcgaaacc ttcgcagtct caccaacctt tttcacttcc ttggctaatt ccttacgtgt
    17161 ttcttctgta agcgctggaa taaccaagcg gatgacagag ccatcgttag ctggtgtaat
    17221 gcccaaatca gaagcattca aggcacgctc aatatccttg attgatgatt tgtcaaatgg
    17281 tgaaatcaaa agcacacgcg cctctggtac tgtaatagaa gccaattggt tcaacggcgt
    17341 tggtgcacca taataatcca cctgaatacg atccaaaagg ctagcattag cacgacctgc
    17401 acgaatgctt gcatactcgc gtgctagtga gtgatgtgac tgtgtaaaac gttctttcgc
    17461 agtttcaata attgcatttg ccatgattgt ttttctcctt aatcctttag ctctaaaatc
    17521 ctaatcgcag gccttatttg ataccgttgt gccaatatgc tctccaaaga ccacacgctt
    17581 gatatttcct gcttcattca tattaaagac aaccaaatca atatcattat ccattgacaa
    17641 ggttgaagct gtcgcgtcca taatcttgag accgcgcttg ataacctccc catgagtcaa
    17701 ttcatcaaac ttaacagcgt ttgcgtcctt tcttgggtca gcattgtaga caccatcaac
    17761 accattttta gccatcaaga tagcatctgc ctcaatctca gcagcacgta aggccgctgt
    17821 cgtatctgtt gaaaaataag gtgacccaat accagcaccg aaaacaacaa tgcgcccctt
    17881 ttccagatga cgaagcgcac gacctcgaat ataaggctct gcaacgtttt gcatgggaat
    17941 agctgtctgc acacgagtat caacgccata atgctgaagg ctatcagcca ttactagagc
    18001 attcataacg gttccaagca tgcctgtgta atcagcctgc acacgatcca taccagcctc
    18061 tgcagcaggc tcaccgcgcc agagattacc accaccaata acaagagcaa tttcaacacc
    18121 tgaattgtga acttctgcga tctctttagc aatcgactga accgttgtta tgtcaatgcc
    18181 aacaccctta tcaccagcca aggcctcgcc agacaatttg attaaaatac gttgatattt
    18241 aggtttcact atttatgatc tccttatttt gtccctacca ttctaccaca aaacaaaaaa
    18301 atttaataga ccaatgcaag agaggaaagc gaaatttttg acgatccttt tatcaagatc
    18361 cctttgagca gcaaaaaaga tgagtcatta taaaaagagc attatcgtat ccgaatagca
    18421 cagttataac ctattaatac gacaaaaacc agaacaacta tgacaaaaaa cgccgtaaaa
    18481 aagacttaaa atcaagcctc aagccagact agattctaag tcgtgctata ttgagagatg
    18541 atttgtttta gttatctagc ccaatgccgc cacaagaagt ctgaggctcc ttatctctga
    18601 cagcaactag cctcccctgc tccagcagca gaacacgatg acaaatggcc tgacagatat
    18661 tagcatcatg cgcaataaaa atataagtca gttgatactc ctgctttaac tcatagagca
    18721 agtccaatag ctgcccttgg gtaatagggt ccaagccact caaagcctca tcaaaaatga
    18781 tcacctccgg ccttaacaaa agagctctcg ctatacaaac acgctgtagc tgaccaccac
    18841 tcagctctct ggccttttta cccagatgag tggcgtcaag accgaccgca gctagtattt
    18901 gaacaacctc ctctaaggca aagtccttag aaagggcctc tgtcaatatc tcttgaatag
    18961 taaagagggg attgactgat cttagcgcat cctgaaagac aagtaaaatc cgaggtccac
    19021 atacttttac agaatagggc tgaccatgaa agagcacctg accagctgtc ggctgctcta
    19081 gcccaatgat taacctagca agcgttgtct tgccactacc actttctccc ataatcccaa
    19141 ggctctcacc cttttccatt tgaaaatgac aatctgttag cactggcttt tgatgaaagc
    19201 tcttataaac atgtctaaac tctatcatag cgtatcagcc gatcataatg attttgcaaa
    19261 agcaactcct tggtggcagc ctgacttggc cgatgaaaaa tcgactcaac acttccctgt
    19321 tcgatgattt ttcccttact catcaccagt agttgccctc ccaaagtctg tgccaattgg
    19381 taatcatgcg tcactgtaat aatggttttt cccttgtcct gcaataactt cagcatccgt
    19441 atgatattag aacgattggc atcatctaaa gcagaggtag gctcatctaa aatgataatc
    19501 tgtgggtcta agcacaacaa aatagctagc attacccgct gtagcatacc accacttagc
    19561 tcaaaggggt acttcctcag cagctcctct ggctgctcta gatagagctc tcgcatgaaa
    19621 ggcagagccc tttttagaca ggcccttttt gaaagtctct catggcttcg gatggtttca
    19681 aggagatgag cctcaatggt ctgaaaggga ttgaacatcg ccataggatt ttggaccata
    19741 taggccatgt ggcgccctct aatgctctgc cattgcttag catctaattg atctagtctc
    19801 atatcttgac aggtaatcct ccctgtcatc tgtacattcg acgggcattg accaattaat
    19861 agcttagtca agagggtctt gcccgaacca ctcctgccaa caatcaccaa ggagctcccc
    19921 aagggcaact caagattgag cttacttaat agcacatcag agccattata agccgataaa
    19981 tcattaacaa ttaaccgttc catgttttcc tccacccctt agcatcagcg taatcaccta
    20041 ggctgttaaa agctagcaca gtcactaaaa tggcaagccc tggtgacatc atgagccaca
    20101 gagctgtcct aaaatagctc cttgcatcat gcagcatcat tccccattct gtcacattgg
    20161 gctgaacacc gatacccaaa aaagaaaagc ttgagatcat gagaataata ttgccaatat
    20221 tcatcaaagc caacactaca atcggccgat aaacaaatgg caggatatgc ttttttaaga
    20281 tatgccgcac agataagccc attgtctgcg cactaatgac atatggctct gccttagcgc
    20341 ttttgaccat cgtgaccatc agcctagcat aatacagcca ctctaccaga acaatagcta
    20401 ggatcatgtt gcctatgccc tgcccaagta tccccattgt agctagcgat agtaaaaagc
    20461 taggaaaggc agaaacaaca tcagctagcc acagaaaagc tgcctcgagc cttccttgat
    20521 accagcctac aaccaaacca accacagcac caatagatag ctctaacaaa ctaatagtaa
    20581 ccgccaaaag caaggaatac ttagccccat ataacaagcg cgacagcaca tctcttccca
    20641 attggtcagt tcctaataag tgctgctgac taggtggcat gagcttacta gcaacatcaa
    20701 cagcatgagg atcaaaggga gcaagataag gagcaaacaa gacacagata aacaacagca
    20761 atagcataac agctgaacca attacgtatt tgggcatgct tcctcctttg tcttgcgcag
    20821 acgagggtca ataaaagaca ctagctcttg agttatcaca tggtgtagta aaaacaaagc
    20881 accaaataag agcatacagg cctgaataac cggaatatct gctgctttca gactcataac
    20941 aaatagactg ccaataccat tccatgagaa aatatcctca acaataatag agcccgtcat
    21001 caaataaaca aaggtcaagc tcaagcctgt tgcaatagca ggaaaggcat ttctaatcag
    21061 gtgatgctta acaatataat aggtcttaac ccctcttagc ctggcatttt caacatgcag
    21121 actcgttagc tgctcactga ttgcctttcg tatcaaggca gtatattgcc caatcaagga
    21181 aaagctaagc gtaatactcg gcaaaatgag gctgctggca cccgccttgc ctgacacagg
    21241 caggagattt agcttaacag aaaaggctat aatcaagaga tagcccaacc aaaagctagg
    21301 cattgacaca gcgacaaagc tgaataaacg caccagccga tcaaacaagg aatgctcaaa
    21361 caaaccactg cctaccccca aaggaaaggc aatcacaagt accagtaaaa aagaggtcaa
    21421 gcttagcatt agcgttgcta aaaagcgctc caccaccaaa ggcaggacag ggacctttaa
    21481 cacgtaagag gtcccaaaat ttcctacaag aatgtcagat aaccaggtca catactgctc
    21541 ccataaaggc ttgtctaagc ccaaatagag cctagcattg tgaagagctt ctggtgtaat
    21601 actgatctta gataggcgca aatactgctc tgccgggtta gcggaggata gcttaaccag
    21661 aacaaaggtc actatcgaaa tcattagcaa ggcgccaaag gtagaaataa gcttcttcat
    21721 catattttct ctcaaccctt cactaagaca tcagacaaga attgtcagga tagtcactca
    21781 caaccagttc ctctgctcta tcaattcttg actgccttat cagcagcact tttttcaatg
    21841 taacgcaatg gaagggcatt ttcctctggt gcaaagcgca ttgtcttaaa atctcccttg
    21901 cgatatactg aaacaactga ctgataggtg agtggaatat aaacagcctc atcatgcaac
    21961 aatgacaata cctgcttata gcccttgtct accttatccc catctggctc aatcaaaaca
    22021 gatttaatca ggcgatcaat ctcagccttt gatggcaaac tctccaaggc aatattttct
    22081 gggtgaccat gatccgcttt tgccgttaag gctgtcatcc aagcatgagg atcccaagga
    22141 gctccccatg aataggtcag catcatatca aactgccctg tcttggcatt agcccagtag
    22201 tcatcctcct ccatagctgt caagaccaca tcaatcccaa gctttttcca ctcgccttgg
    22261 aaatattcaa ccaaatcctt gtctgtcgct ttagttgaaa tataaggcac ctgtaaacgc
    22321 aactgctgac catctttttc cctaatccct tcttggtttt ccttccagcc agcggctgtc
    22381 agcatgtcct tagccttttg gagattgtat tcataaggaa ctaagcccgc atcagcatgc
    22441 ggtgttgttt ttgaaaaaat ggtatctgct gctgtctctg ttcctctaaa ggtgtgctta
    22501 gcaatagcct ttttgtcaac cgcatggttc attgcctgac gaacccgctt gtcctgaaac
    22561 actgactgct tagcatttaa cagcaataaa cgagtcgaca tgggctgaga aacatcagta
    22621 acatacttct tgtccttagc atactgcaca aaggtatcaa gactaatcag accatttcca
    22681 tagatcaaat caatatcccc agcctcaaat gctaaggctc ttgtctcagc atcaggcata
    22741 atcttgatgg ttacttcctt tagctttggt ttttctcccc aatagctctc atgacgtgta
    22801 aaggtaatgt actcatttgc ctttttctct ttaacaaccc attgacctgt accaatcggc
    22861 tttttaacat tgtgcttatt ggtgtcatcg ccatcaggaa aaccagcatc agccaaaaac
    22921 ctaatcggtc tgatcattga caaatcatac aaggtagcgc tataagcctc ctttagctta
    22981 atctcaaagg tatgatcatc taaagccttg tagctatcca attgattggt aaagtgaaac
    23041 caattatgat tgcccttatt ctgctcagag aaaatcgaat caaaattccg tttaacattt
    23101 tgagcattaa aatcagaacc atctgaaaat ttagcctgtc tcaggttaaa ggtataggtt
    23161 ttgccatctg ggctaatcgt ccagctctct gctaacgccg gctcaatatt acccttgtca
    23221 ccatatcgaa ccaagccctc ataaaccatg tcttgaataa caaactgatc aggattgtag
    23281 cgatgaggat tgacatcacc aaaatcctca ccccaagcaa tcctcaactg atccgtacgg
    23341 taagaggcct gcttagcatt ttgacaggcc gtcagcagca aagcaaaaaa gaataacaat
    23401 agcacattca atttagtttt cattatgtca ttaactttct aaagatatta atctatctaa
    23461 ttttagatgt ggtttatcac aaaattaagt atggttaatt taatcatttt atagccctct
    23521 tgtcaagaaa aaatgagaca aaatcagcct agaaaaagcc agaaggctac aaataagcaa
    23581 atcgtcaaaa tcatgaacac ttcaggcttg ctgaggaata ttttctaatg gttattagaa
    23641 ataatgaaca attacctaac aaaagactcc aaaataaagg taaaagacga acattcacct
    23701 tgctgctcag ctaccaagac aaacaatcct gatagcatca attttcttta ggctcttagc
    23761 aattagttgc aatatcagat aattttgaat ttaattaaaa aaaacgaaac tacggagacc
    23821 aattatcaga aagctattca cagccagcaa agggcatgct aaagtattat ctggaaaaag
    23881 aaaggcttag gaatgattat ttctaaacta aaaggagaga gacaatgaaa aaaacaatga
    23941 agaagatgct agcagcctcg acgctctgta tcatcatgtc aggcagcttc atcagcggct
    24001 cagctagagt gttagcggag gaatattatg ggtggaatga tgtcactggg tctaagtcac
    24061 catttcctct atacgtgaca ccaaaaaatg gagataaaaa tataaaagtt caacaaacgg
    24121 ttgtttactg ttttaacagg gatgggcaat ggccagaaaa ttgggaaaaa cggatatatg
    24181 aatctcctga taaagttcca cataaattac ccgaatataa taaaaagtca ggaagcgata
    24241 atctgtttca attacttaat cccaaaatta agataaaaaa tccaatggca gctttattag
    24301 cggttttgga agatggatat cctacgtcat cttcttcagg agtaaatcaa agaacaactc
    24361 agctagctat ttggcatttt acagatggat taagcaatct tgcccaattt catcttactc
    24421 cggaagaaac ttcagcttat aacaagttga tagaaaaagg gacaaatgct tctaatcaaa
    24481 gtgaaaataa actattaaat aaaactttag atatttattc ctatatagat gggactggtg
    24541 ataagaaaca caattatcaa caccttcttg gctccactcc aattcctatt gataattcta
    24601 aagaaaataa atgtcaatgt acaaaagttg acttaatgcg aactggagat ggggttaaaa
    24661 tcattgttta tgttgataac aacggaaata atagatatga caacggcgac aaaatgctaa
    24721 aagaagaaac tatcaaacat ggtcaacgcg gacctgctgg tgaatctggg aaaccagggc
    24781 ctaaagggga tcgaggagaa actggagcac gcgggccagc tgggcctcag ggcaaacctg
    24841 ggaaacaagg acctagaggt gataaaggag aaaccggaga acggggacct caaggggaaa
    24901 aaggtgaacc tggaactcct ggtcctaaag gagaagacgg taaagacggg gctcctgggc
    24961 gtgacggaca accggggcct aagggtgaaa aaggtgaccc tggaaaagac ggacaagatg
    25021 gaaaaccagg ggaaaaagga gaacctggaa ttcctggtcc taaaggagaa gacggtaaag
    25081 atggggctcc tgggcgtgac ggacaaccgg ggcctaaggg tgaaaaaggt gaccctggaa
    25141 aagacggaca agatggaaaa ccagggaaaa aaggtgaccc tggacgcgat ggtaaagatg
    25201 gagaaaaagg cgaacgcggt gaacaagggc ctaaaggaga acgcggtgag cagggacctc
    25261 aaggagagcg tggggagcaa ggacctcgtg gggaaaatca tactcctacc ccagacccaa
    25321 tgcctgagcc ggcacctaaa ccagaatcca aacctgaacc taagccgaca cctcaaccag
    25381 aggttaagcc tctgccagag actaaacctc aaaaaccaac caagccgtca gcaatggcta
    25441 gccaaccaag tagcaaagca ctaccaaaaa caaatgacac tagcggctta atgactgtac
    25501 ttggaacagg cttgctctct cttcttggat taggcttcct ggcaaaacgc aaaagaaagc
    25561 aataactaac acataatcat tagtaatcca ttcattatcc atttacaagt tatcataaaa
    25621 aagccttatc attccttgac tggtatgata aggctttttg tttaccctat atagctctac
    25681 ccttactcca aaaatcactt aaccctagga aaaggctgac tatcattttt ggccaaaaaa
    25741 agacagacac caattcatga tgtctgtctc aaaaccaatc ccttttaggg tcagtcctta
    25801 attacttatt aaaatgaact tggatctacc ttgataccca caccttgtgt agttgtgata
    25861 gatacgttag tcatgtaagt accctttgca gtagctggct tagccttaac cattacctca
    25921 tggaaagcct taaagttttc aaccaacttg tcagcgtcaa atgatacttt accaatgata
    25981 gcttgtacgt tacctgcttt atcagcacga taggtaattt taccaccctt agactcttca
    26041 accgccttag caacgtccat tgttactgta ccagttttag ggtttggcat caagttacga
    26101 ggtccaagga cacgtccaag acgtccaaca atagccatca tatctggtgt tgcaataaca
    26161 acatcaaaat caagccagcc gccattgatc ttagcaacaa ggtcatcttc accaacgaag
    26221 tctgcaccag ctgcctttgc ttcttcagct tttgctccac gagcaaaaac aaggacacgc
    26281 tgagttttac cagttccgtt tggcaacacc atcgcaccac gaatttgttg gtctgccttg
    26341 cgaacgtcga tgtttaagtt ataagcaact tctacagaag cgtcaaattt tgcgaagtta
    26401 gtttcttttg cgagtgctac agcttcctct acactgtatg cctttgtgct gtccactttt
    26461 tcaagtgctg cacgcatttg tttgcttttt ttagccattt ttatcttctc cttgtaatgt
    26521 ggtcatatcg atttgattta aaaatctccc acgtcactca tctctatgat gaagtcttgc
    26581 gggtaataag ggcaggttgc tgattaatca gtaacggtga atcccataga acgagcagta
    26641 ccttcaatca tacgcattgc agcttcaatg tttgcagcgt ttaaatctgg catcttagtt
    26701 tcagcaattt cttgtacttg tgcacgagta actgtcgcaa ctttagtttt gttaggtgta
    26761 cctgatcctt tttcaacacc tgcagccttc tttaaaagaa cagcagctgg tggtgtcttt
    26821 gtgatgaaat caaatgattt gtcttcgtaa actgagataa caaccgggat aatcatacca
    26881 gcctgatcag ctgtacgagc attaaattcc ttagtgaatc ccatgatgtt gatacctgct
    26941 tgaccaagag ctggtccaac tggtggagct ggtgtcgctt taccagcagg gatttgaagt
    27001 tttacaagtt tttcgacttt tttagccatt tttaaaaatc ctcctgttgt ggttttggcg
    27061 gtaattcacg atttttacct cccacaggta tgctagagca taccttacca ttatacctta
    27121 ttagacagat aaatcaagtc attttcacaa aaatgttacc gcaaatagca gatgtctcct
    27181 atggcactag cagtacaagc atgtgaggct tccaaggagc cgcttctagt tgacttttaa
    27241 gcgttttttt attataacaa agctatgcat aagaaagtta cgatcaaaga tgtcgcacgc
    27301 gaggcgggag tttctgtggc tactgtctcc tatgtcatca ataacagaga agatcaaaaa
    27361 attagccctg aaacgcgcaa taaagtgctg caaatgatta atcttttaaa ttatcggcca
    27421 aaccaagccg caaaatcact cgtgacacaa aaaagacagc taatcgccct ttactacaaa
    27481 gagcacagct ctgttttaaa aagagcagag cagcttcact ttatcaccca gctatctgcc
    27541 tttctttaca caaagcacta tcacttgatt tgccttaatc aagaatacat cggaaaatat
    27601 gatgtagcag atgtcattct caccctagag gtcaccaaag aggaatttta caagatcgga
    27661 aatagcaact ttgttccttt gattgctatt gatagtatta ttgatgatcc cttatttttc
    27721 cagattaata gtgaccctca tctcctgttc aataaagcca gtgcttattt tgcaggggag
    27781 ccctttgaac tggttagcct gcctattcaa aaccaagaaa tcactcaagg actcgctcaa
    27841 cagtttgata acatttgctg gattcactct atttgcgaca tcgaaagcgt gtctaagggg
    27901 aatattctag ttattgatga tactgtcaat catattctta gtaagcacaa gaacaaacta
    27961 tacctgccaa gtatctcaga agctaagctt ctgaagcttt ttcaggctat tgagtgggct
    28021 tccaaaagag aagcaatcaa caatcataat attttggttt aaccatgata agagcttagc
    28081 aacaagcttg ctgctaagct ctttttgttg gtcaagaggc caactttatt taggtatcag
    28141 tcagtgtgcc agctctttta gccactaaaa gcaggaatta gtttacaagt ctaccaattg
    28201 ggtataaaat agacttatga tcatctacaa attaacagcc ttagccttta ttatcctgac
    28261 tcccttattc tctatgataa tgatatccct attgagactg ggacgaagag gccttaaatt
    28321 tcctgattta gccttaccac tttttgtttt tgaaattgtt attgtatcag gaaaattttt
    28381 cacccatcat ttactacctt attacctgat tgttatgtcc ttgttggcca ttgttatggc
    28441 actcttactg attatcagaa tccagcagtt ttcttaccgc cgatttttca aactattttg
    28501 gcgagtaggc tttttagtca cactactctt ttacctgatg ctagttggtc ttatttttat
    28561 cgtttagtgc cttaccagac atggcttcaa gcctagcagt ctgaatctgc caattaactc
    28621 tagcactatc actcaaaagg aagctgtctt tgaactttct gcttgagtgg gacttttttc
    28681 aaagcaatca atccatatca aaccagcatt agagcatgcg gcttgatacg gattgattgc
    28741 tttaagaact gttgtaaaat atcaaaaatt cagtttttaa taaagtccat tagctatttc
    28801 tacactaaat atcatttaag aaaacagagg ctaataacta gagttcacta taacctaaaa
    28861 tcaccaatac ctccgattaa cttaatttaa ccaaactact gtatatacca aagtttttta
    28921 cgtgtcatta taatacgttc agataaatca tctaatgcac gatctttgtt gagaccaaca
    28981 tcatattgaa tacccattaa tctatctaga aactcaagac gatatttctt cataatattt
    29041 cgtgagtgtc cttctggaaa atgctcatca ataagcgaac ttacaatctc aactttatta
    29101 ctaattttaa aatagcgact tttcaaagat tgtaattctt ctttaattgc tcttaattta
    29161 gaaaaactat ctgctccata aaccttagct tccatttcat tagcctcaga ataacttagt
    29221 tttattgttg caataaaatt tctaagtact tccttctctt ttttaagctc cctttctgtc
    29281 ggactcattc tatagtaata ttgacgccaa cgatattgag aagcgttgac tttttgatca
    29341 cttatagtca aaatagtcaa tgctactaca ctaaagaaaa atattctttt cgtttgcagt
    29401 ttctcct
//
LOCUS       DARYXW010000016        28984 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.016, whole genome shotgun sequence.
ACCESSION   DARYXW010000016 DARYXW010000000
VERSION     DARYXW010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28984)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28984)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28984
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.016"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            748..2580
                     /gene="lepA"
                     /locus_tag="TV191_000579"
     CDS             748..2580
                     /gene="lepA"
                     /locus_tag="TV191_000579"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEL1507117.1"
                     /translation="MNSQELKKRQENIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYKAKNGQDYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GLDASEAVLASAKSGIGIEDILEQIVEKVPAPSGDVDQPLQALIFDSVYDAYRGVILQ
                     VRVVNGMVKPGDTIQMMSNGKTFDVTEVGIFTPKAIGRDFLATGDVGYIAASIKTVAD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVNITDGDMLE
                     VSNPSEFPDPTKVDSIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYHIPLAEIVFDFFDKLKSSTRGYASFDYEIAEYRRSQLVKMDILLNGDKVDALSFI
                     VHRAFAYERGKLIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDESKK"
     gene            3122..3559
                     /gene="msrB"
                     /locus_tag="TV191_000580"
     CDS             3122..3559
                     /gene="msrB"
                     /locus_tag="TV191_000580"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEL1507118.1"
                     /translation="MESKEELRQRIGDLAFEVTQHAATERAFTGQYDDFFEKGIYVDV
                     VSGEVLFSSLDKFNSGCGWPAFSKPIQHRMVTNHHDSSHGMRRVEVKSREAGSHLGHV
                     FNDGPKEAGGLRYCINSAALKFIPYDQMEQEGYAEWLGIFDKS"
     gene            3847..4866
                     /locus_tag="TV191_000581"
     CDS             3847..4866
                     /locus_tag="TV191_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEL1507119.1"
                     /translation="MLTSLEKLPGVLLCLLLALPAWYLGSLFPIIGAPVFAILLGMLL
                     ALVYQKRDYTKSGIALTSKYILQLAVVFLGFGLNVTQVLVVGLQSLPIIVVTIVTALG
                     ISYLFKRWLRLPAKTAILVGVGSSICGGSAIAATAPVIDAQDDDIAKAISVIFLFNIL
                     AALLFPALGQMLGLSNHGFAIFAGTAVNDTSSVTATATAWDAIHQSNTLDGATIVKLT
                     RTLAIIPITLGLSIYQTKSRQAHTTEGSFSLRKAFPTFIVFFLLASLITTFAASLGLP
                     MAIFHQLKLLSKFFIVMAMAAIGLNTNLVTLVKTGGKAILLGGICWLAITSVSLAMQA
                     ALGSW"
     gene            5210..5635
                     /locus_tag="TV191_000582"
     CDS             5210..5635
                     /locus_tag="TV191_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000823118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HEL1507120.1"
                     /translation="MKRKFLIGSHGRMASGLKSSIDILAGRGQELQVIDAYIDDSDYT
                     EQVLTFIEDVAADEQALIFTDLLGGSVNQKIVTALMDSGKENIFLISNSNLAALLSLM
                     FLKPEEELTKDEIVATINDSQVQLVDLAPATAAEDDFFN"
     gene            5650..6141
                     /locus_tag="TV191_000583"
     CDS             5650..6141
                     /locus_tag="TV191_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1507121.1"
                     /translation="MITQIRVDDRLIHGQVAVVWTKELNAPLLVVANDEAAKNEITQM
                     TLKMAVPNGMKLLIRSVEDSIKVFNDPRAVDKRIFVIVSSIKDACQIAKQVKDLEAVN
                     VANVGRFDKSDPATKVKLASSLLLNPAELEAAKELVSLPNLDVFNQVLPSNSKVSLSQ
                     LIK"
     gene            6159..6968
                     /locus_tag="TV191_000584"
     CDS             6159..6968
                     /locus_tag="TV191_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017644846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEL1507122.1"
                     /translation="MLVPATMAALAVLICFGGNYLTGQSMMERPLVVGLVTGLLLGDM
                     KVGILMGASLEALFLGNVNIGGVIAAEPVTATAMATTFTIISHIDQKAAMTLAVPIGM
                     LAAFVVMFLKNVFMNIFAPMVDKAAAANHQGKLVMLHYGTWIVYYLIIASISFIGILV
                     GSGPVNAFVEHIPQNLMNGLSAAGGLLPAVGFAMLMKLLWTNKLAVFFLLGFVLTAYL
                     KLPAVAVAALGAVICVISSQRDLELDAITKGAISNQSSFDSKESEEEDFFA"
     gene            6965..7792
                     /locus_tag="TV191_000585"
     CDS             6965..7792
                     /locus_tag="TV191_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEL1507123.1"
                     /translation="MRSQDNLTKEERKMLRSVFWRSWTMNASRTGATQYHAVGVIYTL
                     LPVINLFYKTDKDKADALVRHTTWFNATMHINNFIMGLVASMEKKNSEDPTFDASAIT
                     AVKASLMGPISGVGDSFFWGILRVIAAGIGISLASTGSAMGAVVFLLLYNIPAFIIHY
                     YSLYGGYSVGAGFIKKLYESGGIKIVTKTSSMLGSMMVGSMTASNVKFKTILTVAAKG
                     AKEAASIQNYLDQLFIGIVPLLVTMTAFWLLRKKVNINWIMFGIMLLGIVLGLLGIC"
     gene            7982..9616
                     /locus_tag="TV191_000586"
     CDS             7982..9616
                     /locus_tag="TV191_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1507124.1"
                     /translation="MEERFKKRLQDDISHHFSHQSLILSILLIGLFLIFSLAPQQIGL
                     YQDLKAVEHSYHQLIRQNKALLTELNQHILTKFVNHQLSSSDLSKQYYHLRNRSQSQS
                     ELLVFDANSHMLFASNQHLGNFFRNAVYMTEVLKKARQRSSFLRISMDNEEGHYLLLI
                     KPIKIDHQVKGYSLLVMNGKDFLQLSHQIASDFVIADQFDNSFAFTNRTFMTSSLNKL
                     DSHFLKGYFIFHEHRAFILRKVALSPSITLYSYRPLIPVSIALLFSLMSSVMIYAILY
                     WKSKALATQIASSNSAAINQMILDMQAISRQEKNAIDLQSQDEFQYLSVQINQMISRL
                     QALHQKTLALEKQNVSFEKRMLEAQFNPHFLYNTLETILITSHYDSDLTEKIVLQLTR
                     LLRYSLDESQEAVCLGEDLAVLESYLLISQIRFEELRYTIAVEPALETLRVPKLFLLP
                     LIENAIKYGLRYRHDLVIEISVRQLADGIYFTVADNGPGISQKRQADIKELLHSEDSH
                     HGLVNSYRRLKHQFIKVELIFCQRDERFLLTYMVKE"
     gene            9620..10405
                     /locus_tag="TV191_000587"
     CDS             9620..10405
                     /locus_tag="TV191_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1507125.1"
                     /translation="MYKLLIVEDEHIIRKWLRYAIDYHALNILVIGEAKDGQQGAKLI
                     AEAKPDIVLTDINMPIMTAFEMFEATKEQSYAKIILSGYADFANAKSAIHYGVLEFLT
                     KPLERQALHDCLLTIIQKLQQQSQEQELSQQQDYLKLPQPNDQLPDVVQEMLSWIHEH
                     YQDKIMIGQLAHDLGYSESHLYHLAKKYLKMTFSDYINQYRLNRAIQLLIAEPDVMVY
                     QLAEAVGIYDYRYFDRVFKKYLGQTVKDFRETVLHQRSDRSSL"
     gene            10429..11439
                     /locus_tag="TV191_000588"
     CDS             10429..11439
                     /locus_tag="TV191_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL1507126.1"
                     /translation="MAIVILGVIGSGLYAIWRHQAGPAPSKPRELVVLTPNSQNILTG
                     TIPAFEEKYGIKIRLIQGGTGQLIDRLQKDKDQLHADIFFGGNYTQFESHKELFEPYL
                     SKHIGFVLPDYLLQSEVATPYTLNGSVLIVNNELAKDMVITSYEDLLKPELKGKIAFA
                     DPNTSSSAFSQLTNILLAKGGYTNPKAWSYIKQLIHSMNSIKSASSSDVYQSVAEGKM
                     TVGLTYEDPCVNLLKSGANVSIVYPKEGTVFLPSAVAIVKQSKAKADAKLFINYMLSL
                     DVQRAFGQSTSNRPIRKDAKASQDMKPLDDIITLKEDYDYITRHKKDILERYNQLRKT
                     TD"
     gene            11692..13476
                     /gene="uvrC"
                     /locus_tag="TV191_000589"
     CDS             11692..13476
                     /gene="uvrC"
                     /locus_tag="TV191_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEL1507127.1"
                     /translation="MNELIKHKLELLPDSPGCYLHKDKAGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTELLVSEIADFEFIVTGSNTEALLLEINLIQENMPKYNIKLKDDKSYPFI
                     KITNEPFPRLLITRQIKKNDGLYFGPYPDAYTATEVKKLLDRIFPFKKCKNPVNKVCF
                     YYHLGQCQAHTICHTDKAYWDSLVADVKQFLNGKDDKIIDDLRSKMLEASHNQEFERA
                     AEYRDLISGIATMRTKQRVMSKDLQDRDIFGYFVDKGWMCVQVFFVRQGKLIQRDVNM
                     FPYYNEAEEDFLTYVGQFYSDQRHLIPKEVFIPETIDETLVAAIVPARIVKPQRGEKK
                     QLVALATKNARVSLQQKFDLLEKDLRKTSGAIEHLGQLLGIEKPVRIEAFDNSNIQGT
                     SPVAAMVVFVDGKPSKKDYRKFKIKTVIGPDDYASMREVIYRRYSRVKHEGLQAPDLI
                     IVDGGQGQVKAARDVIEHQLGLSIPVAGLQKNDKHQTHELLFGNPLAVVELPRNSEEF
                     FLLHRIQDEVHRFAITFHRQVRSKNAFSSKLDHIAGLGPKRKQLLLKRFKSMTALEQA
                     SLEEIQQLGIPKTVAEALFDHLTSKSEV"
     gene            13604..14206
                     /locus_tag="TV191_000590"
     CDS             13604..14206
                     /locus_tag="TV191_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEL1507128.1"
                     /translation="MKFLELNKKRHAIKRFNDKPVDYNDLRTAIEVATLAPSANNIQP
                     WKFVIVEEKKAELAKDLPLANKTQVEQAQYVIALFSDTDLIQRSRKIARIGVKSLPDN
                     LIGYYMETLPPRFATFTETQKGEYLAINAGLVAMNLVLALTDQKMASNIILGFNKKLT
                     NEILDIDPRFRPELLITVGYSDDKPEPSYRLPVDEIIERR"
     gene            14287..15696
                     /gene="pepV"
                     /locus_tag="TV191_000591"
     CDS             14287..15696
                     /gene="pepV"
                     /locus_tag="TV191_000591"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEL1507129.1"
                     /translation="MTTIDFKAEVDKRKEAMLEDLSNLLSINSERDDAKADAKHPFGP
                     GPVKALEFFLAMAERDGYQTRNIDNYAGDFEFGQGDEVLGIFAHLDVVPAGSGWETDP
                     YKPVIKDNRIYARGSSDDKGPTMACYYALKIIKELGLPVSKRVRFIVGTDEESGWGDM
                     DYYFAHNGLKNPDFGFSPDAEFPIINGEKGNITEYLHFVGQNAGAFVLHRFQGGLREN
                     MVPESATALISSPHELNVIEASLEQFLSEHAVTGSVKEADGLLEVTIIGKSAHGSTPE
                     AGVNGATLLAKFLNQFSFDGAAKAYLHIAGEVLHEDFTAEKLGLAYTDDKMGALSMNA
                     GVFSFAKDSDDNTIALNFRYPKGTNAAVLKAGLEQLPGLTKVTLSEHEHTPHYVPMDD
                     ELVSTLLSVYEKQTGLKGYEQVIGGGTFGRLLERGVAFGAMFPGDENTMHQANEYMPL
                     DNIYRSAAIYAEAIYELIK"
     gene            complement(15963..17339)
                     /gene="mnmE"
                     /locus_tag="TV191_000592"
     CDS             complement(15963..17339)
                     /gene="mnmE"
                     /locus_tag="TV191_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002888396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEL1507130.1"
                     /translation="MSITKEFDTIAAISTPLGEGAIGIVRLSGTKALDIAKSIFKGKD
                     LTTVASHTLNYGHIIKPSTGEVIDEVMVSVMLAPKTFTREDVIEINTHGGIAVTNDIL
                     QLLIKQGARMAEPGEFTKRAFLNGRIDLTQAEAVMDLIRAKTDKAMSIAIKQLDGSLS
                     QLISDTRQEILNTLAQVEVNIDYPEYDDVEEMTTALLRDKTREFQTLLEQLLRTAKRG
                     KILREGLSTAIIGRPNVGKSSLLNTLLREDKAIVTDIAGTTRDVIEEYVNIKGIPLKL
                     VDTAGIRETDDLVEQIGVERSKKALQEADLVLLVLNASEKLTEQDKALLALSQDSNRI
                     ILLNKTDLEQVIEKDQLPEEAIPISVLQNQNIDLIEDRINQIFFDHTGLIEQDATYLS
                     NARHISLIEQAVQSLEAVNEGLALGMPVDLLQIDLTRAWEILGEITGDAAPDELITQL
                     FSQFCLGK"
     gene            17611..17832
                     /locus_tag="TV191_000593"
                     /pseudo
     CDS             17611..17832
                     /locus_tag="TV191_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623017.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
     gene            17955..18269
                     /locus_tag="TV191_000594"
     CDS             17955..18269
                     /locus_tag="TV191_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04197 family type VII secretion effector"
                     /protein_id="HEL1507131.1"
                     /translation="MVVLQNNSSTASERATALARGVQALSSAGAVSKDMKTTVTGNRS
                     DASSAIDLSHNVSAQVVGIIASMSQHIQSVSASFQAMDLQLGKELGRLENRRRFSLND
                     PK"
     gene            18274..18606
                     /locus_tag="TV191_000595"
     CDS             18274..18606
                     /locus_tag="TV191_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3958 family protein"
                     /protein_id="HEL1507132.1"
                     /translation="MYQKERLDKRLETIAQELKRNEQRFEDYEELSNLAAQLLTAAAT
                     TFRSSSDSHLFEGALAEECYLKRKTQASLEQSHEELLGEQRRLYQEEEALTRQLKLVK
                     GKERANEH"
     gene            18608..20206
                     /locus_tag="TV191_000596"
     CDS             18608..20206
                     /locus_tag="TV191_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507133.1"
                     /translation="MYLGSSDQQASSVGKVLQQRITAYKSLQRALEQLVSSSPDLSGH
                     TYASAKRYSEQVLIPLMRGCILLDEAIKEACAAFPNDYRRQVDSVDLKESELVDQISR
                     SDRIIGRYVELIDLEYRQELPNYSYITNLKSGASNQRQVKRKLEEKLLKLREFDSNSR
                     HLFSSIAALAEAVNIGIRQTKTSWNGTSQTFTLPRALDLEWTKVVEKRWTQREEKASK
                     LKLQQAAEKLSRETGIKYEDAYRFVMDGVLSDENKNKIKSVKKLVKYTKGGLYIVSSG
                     RYYWKHSGKHYWKNTPNKTWNIWKASKNDPNFDKGGIKGKHFSKKGARYTDLPGIKQL
                     KKSETVQSLISKISKDNQGKLTKVGKGLKKVDKELSNISSKLKSYEHGRLNRDLKMMK
                     ENNLGKSLGKFGKVGKAASKVLKFAGKGLKVAGWVGAAINVKDSVETYKKKGYSNEQT
                     AALTARKVAVDTATTVVGSNIGRVTGAVIGQAVIPIPGVGAAIGSVAGSILGAMAGSW
                     IGSTINDNLDKNVKPKQSGRSLAW"
     gene            20200..20886
                     /locus_tag="TV191_000597"
     CDS             20200..20886
                     /locus_tag="TV191_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507134.1"
                     /translation="MVMLMRTLLFPVDNGLDSGLTGDGYAAEYDLWTGKVTWRQLGDG
                     KIKRQQKVAAIINLIAAAISPLVIMSIIFTAKSLKLFDVDTSTTIYRYAPLMVGLVFF
                     FSFELLMLAIRRLYPLAKEEPSLKRQHGYFKTMYDNTIRENDGVFNNLSVPFIGLYVA
                     FLIAFSVIPIFYSQYLQQNSFWSYLGNLVGSSILISLVPNFLWNVLVKQLIYIKLIRK
                     TKEKILKNET"
     gene            20908..21594
                     /locus_tag="TV191_000598"
     CDS             20908..21594
                     /locus_tag="TV191_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507135.1"
                     /translation="MVMLMRTLLFPIDNGMDNNLIGDGLSAEYDLWTGKVTWRQPSDD
                     KIRTQQKVAFVLNLIAGSLSPLAIFLFVIIVRRLGVFSGDTNSMIFKWAPLIVGFILF
                     ISFELLMLALRSRYTILEKEPDLDRQLYYYRTMYDNTIHDNSGVFNNLSVPYVGLYIT
                     LFLIFLIIPLCYHFYLHPSSFGDYLAALSVTSLLISLFPNFLWNGVLKHVIYVKLIRQ
                     TKERILKNET"
     gene            21616..22293
                     /locus_tag="TV191_000599"
     CDS             21616..22293
                     /locus_tag="TV191_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507136.1"
                     /translation="MVMLMRTLLFPVDNGMGTGLTGDGYAAEYDLWTGKVTWRQATKQ
                     TIEKQQALTSNLLIIASCLSPVTVAGMILLSRSFPIFEEDLSEKIDTYAPIILGVVLF
                     LAFETLMLAIRGRDPLAEKEPDLKRQHDYFEKMFDFAIRRNLSSDNLKTPYIATYFAF
                     GISLLCIPFSYYVYLNPEQFPNLDYGHLSILLVTSILISLVPNFLWNVLLKHIIYIKL
                     IRKTKGQ"
     gene            22300..22614
                     /locus_tag="TV191_000600"
     CDS             22300..22614
                     /locus_tag="TV191_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
                     /protein_id="HEL1507137.1"
                     /translation="MNKPEHILPIGTIVLTETGEIPLMIVSRASLFDDNGEIGYFDYA
                     AVPYPEGIGNDNEYLFFNHEDIADVIYFGYVNSNEQLFAEAYDDLVKTSGYRKLSLDH
                     HQ"
     gene            23062..23745
                     /gene="rpiA"
                     /locus_tag="TV191_000601"
     CDS             23062..23745
                     /gene="rpiA"
                     /locus_tag="TV191_000601"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEL1507138.1"
                     /translation="MEALKKIAGVTAAQYVTDGMTIGLGTGSTAYYFVEEIGRRIKEE
                     GLQVVGVTTSSVTTKQAEGLGIPLTSIDDIDCIDLTVDGADEVDKAFNGIKGGGAALL
                     MEKIVATPTKEYIWVVDESKLVDHLGAFKLPVEVVQYGADRLFRVFERAGYKPSFRMK
                     GDKRLITDMQNFIIDLNLGCIENPCEFGRLLDQTVGVVEHGLFNGMVDKVIVAGQAGV
                     TVLEANQST"
     gene            23823..25034
                     /locus_tag="TV191_000602"
     CDS             23823..25034
                     /locus_tag="TV191_000602"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEL1507139.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDADKFFNAGVADTDSDTLGHISE
                     TAGLAVPNMAKIGLGHIPRPVPLKTVPAEADPTGYVTKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWDGFPEEIIQKIEAFSGRKVIREANKPYSGTKVIDDFGPRQMETGELIV
                     YTSADPVLQIAAHEEVIPVEELYRICEYARSITLERPALLGRIIARPYIGEPGSFTRT
                     ANRRDYAVSPFQDTVLNKLADAGISTYAVGKINDIFNGSGITNDMGHNKSNSHGIDTL
                     IKSLQLPAFTKGLSFTNLVDFDASFGHRRDPEGYRDCLHEFDRRLPEIIANMKDDDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSASCTGAGVIPQGHFADISATIAENFGVDTA
                     MIGTSFLADLV"
     gene            25247..26056
                     /locus_tag="TV191_000603"
     CDS             25247..26056
                     /locus_tag="TV191_000603"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEL1507140.1"
                     /translation="MTLLEKIRETQAFLESKGIDKPEFGLILGSGLGELANEVEQAIV
                     IDYADIPNWGKSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPMEVVTFPVRVMKA
                     LGCHSLLVTNAAGGIGYGPGTLMLINDHINMTGTNPLIGENLDEFGPRFPDMSDAYTA
                     AYRETARSVAEKLGLDLQEGVYLGCSGPTYETPAEIRAFKVMGADAVGMSTVPEVIIA
                     AHSGLKVLGISAITNFAAGFQSELNHEEVVEVTERIKENFKGLVKAILAEL"
     gene            26147..26932
                     /locus_tag="TV191_000604"
     CDS             26147..26932
                     /locus_tag="TV191_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytR family transcriptional regulator"
                     /protein_id="HEL1507141.1"
                     /translation="MTDMEHTISILLEVYAYSHAYKIARTLPDFSPKVLYLLELLKER
                     RELNVAYAFQHRAENRLIEDRHQVKLLLNEAQEEEQTANYLLDLAAKVKNGEIIDFVR
                     SVSPVLYRLFLRLLEQAVPDVQSYIIDTKNDQYDTWNFKAMEKADNDLFRSYLAQRQP
                     RHVTTRSLADLLVLSELPADIKRLVVVLRQFEKSVRNPLAHLIKPFDEEELYRTTHFS
                     SQAFLDGLIRLAVFSGVNYIKEPFYFDVVNAVIEKELLDSAKP"
     gene            complement(27065..27973)
                     /locus_tag="TV191_000605"
     CDS             complement(27065..27973)
                     /locus_tag="TV191_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEL1507142.1"
                     /translation="MRIQQLQYIIKIVECGSMNEAAKQLFITQPSLSNAVKELEQEMG
                     ITIFIRNPKGITLTKDGVEFLSYARQIIEQTALLEDRYKNHNTSRELFSVSSQHYAFV
                     VNAFVSLLKRADMTQYELFLRETRTWEIIDDVKNFRSEIGVLFINDYNRDVLTKLFEE
                     NHLTVSTLFKTTPHIFISKSNPLANKTSLTIDDLLDFPYLSYDQGIHNSFYFSEEMMA
                     HIPHSKSIVVSDRATLFNLMIGLNGYTVASGILNTNLNGDQIVAIPLDVPDVIEIVFI
                     KHEKANLSKMGERFIDYLLEEISFNH"
     gene            28313..28762
                     /locus_tag="TV191_000606"
     CDS             28313..28762
                     /locus_tag="TV191_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507143.1"
                     /translation="MTGQSSHQVLIQKLLVSTHYLTLFRDELKLVERTPSILGSEFPV
                     SLVQTELGDIITLVDTLNKQQRLIESTFWYEESAFKLMNKALDIVDNWIKGIDGLIKL
                     CQSKEVFQAIVGDKRTRVFGVLIDVFSSLKISTMSLKEFAAPAALCH"
BASE COUNT         8241 a         5297 c         6701 g         8745 t
ORIGIN      
        1 gattgccgaa tcccaattta ccagtctttt agagcgaaga gcgacttgaa gaaactgata
       61 aatttatttg gttttctgct aaaaatcctg ccaaaaaatc tttggcagga tttttatttt
      121 actaagagat atttaggagt ggctttgtca tttaatgcag attatgatat agcaggagac
      181 atattgttga agctgtctat gtcacttttg gtggcaggta ggtcttattg gaattggtga
      241 cttatgacat ttatcggtgg ctgtaagcgt ttgacttttt cacgtttcat agtggtccgc
      301 tctggaatga gtgggtattt tttcagaata tgatcaaaga tagatgacat gttttacagc
      361 aggctatagc tggtatgatt tgtttaaaaa atcaaggcca atgataagtg ctgggtgaca
      421 taagtcttat ggctttactt cttgttagct tgtgtcagca ggtgctgagt caatcgttgt
      481 aggaattatc gtaaacctaa cagtagctgc tgttctattt gtttattttc tggtttctat
      541 tcaaatttct aaaatgctag ggtaacaaat atgaaacaag caagtggcgt actgcgaaca
      601 gcttgataac ttattgcctg cttaaagagg gtgctgttat gcttggtttt attaggctta
      661 tggcatggga ttaaaaggtt gctgtagcgc cattgtcatt attttggtac aataataggt
      721 aaaagactaa atgtatagga aaatagaatg aacagtcaag aattaaaaaa acgtcaggag
      781 aacattcgta atttctctat tattgcccac attgatcatg gtaagtcgac tcttgctgac
      841 cggattttgg aaaagacaga aacggtttca agtcgtgaaa tgcaggcaca gctccttgat
      901 tcaatggact tggagcggga gcgtgggatt accatcaagc taaatgcgat tgagctgaat
      961 tataaggcta agaatggtca agattatatt tttcacttga ttgatacacc agggcatgtg
     1021 gactttacct atgaggtgtc ccggtcacta gctgcctgtg agggtgctgt tttagtggtg
     1081 gatgctgctc aggggattga ggcacagacc ctagcaaatg tctatctggc gcttgataat
     1141 gatttggaaa ttcttccagt gatcaacaag atcgatttgc cagcagctga tcctgagcgg
     1201 gttcgtcagg aaattgagga cgtgattggt ctagatgctt cggaggctgt acttgcctct
     1261 gcaaagtctg ggattggtat tgaagatatt ttagagcaaa ttgttgaaaa ggttcccgca
     1321 ccgtctggtg atgttgatca accgctgcag gccttgattt ttgattcggt ttatgatgct
     1381 tatcgtgggg ttatcctgca ggtgcgtgtt gtcaatggta tggtcaagcc aggtgatacg
     1441 atccaaatga tgtcaaatgg aaaaaccttt gatgtgactg aggtggggat ttttacccct
     1501 aaggctattg gtagggattt tcttgctact ggtgatgttg gctatattgc ggcctcaatc
     1561 aagacagttg ctgatacgcg tgtcggtgat acggtcactc tggctacaaa tcctgcagca
     1621 gagcccttgc atggctacaa gcagatgaat ccaatggtgt ttgcagggat ttacccgatt
     1681 gagtctaaca aatacaatga tcttcgtgag gccttagaaa agcttcagct taatgacgct
     1741 agcttacagt ttgagcctga aacctcgcaa gcattgggct ttggttttcg ttgtggcttt
     1801 cttgggctgt tgcacatgga tgtcattcaa gagcgtttgg agcgtgaatt caacattgat
     1861 ttgatcatga cagctccgtc tgttgtctat catgttaata taactgatgg tgacatgctt
     1921 gaggtctcta acccgtcaga atttcctgat ccaactaagg tagatagtat tgaggagcct
     1981 tatgtcaaag cccagatcat ggtgccgcag gagtttgttg gtgctgttat ggagttggcc
     2041 cagcgtaagc gtggagattt tgtgacgatg gattatattg atgacaatcg tgtcaatgtg
     2101 atttaccata ttcccttagc tgaaattgtg tttgacttct ttgataagct gaaatcatca
     2161 acgcgaggct atgctagctt tgactatgaa attgctgaat accgtcgctc gcagctggtg
     2221 aaaatggata ttttgttgaa tggtgataag gttgacgctc ttagctttat tgttcataga
     2281 gcatttgcct atgagcgcgg taagctgatt gttgagaaat taaagaaaat tattcctcgt
     2341 cagcaatttg aggtgccgat tcaagcggct attggtcaaa agattgtggc tcgctctgat
     2401 atcaaggcct tacgcaaaaa cgttcttgct aaatgctatg gtggcgatgt ttcccgtaag
     2461 cgtaagttgc ttgaaaagca aaaggctggt aagaagcgta tgaaggctat tggctctgtt
     2521 gaggtgccgc aggaggcctt cttgagcgtc ctatcaatgg acgatgagag taagaaatag
     2581 tgacatgtta agtaaggagc tggatcatgc gatctggctc ttatgcttga tgtctcgata
     2641 ggctagaaaa tagggcttgt gtcatgatag gcttgtatgt ttgagatggt ttggaacata
     2701 atgactctat catatctgta gtggattgac aaagagccgt aaaccattga tatttggata
     2761 gttaatttcg agttattctg tagtactctc ttaaggtctt tcatatgagc ttttctaatg
     2821 ttggtttggt tgcttttcat gataagtcat atgggatttt tttggtatac tgaaaaaagc
     2881 ctatagcctc tacagtggcg tctccctcta cagagatgat agagccagag tgattgttac
     2941 gatctggaga tgtggcgcta ggcattaatg caggaggact taaccagatt gctgttaggc
     3001 ttgaaatctt aagctatatt gattgtcagc ttgatttaga gaagtctaag tttatggctc
     3061 acaaatgctc ggtctttttg ttacaataga gttaatcagt tatttttata aggagacagc
     3121 tatggaatct aaggaagagc ttcgccagcg tattggagat ttggcttttg aggtgactca
     3181 gcatgcagcg accgaaagag cctttacagg tcagtatgat gatttttttg agaaggggat
     3241 ttatgttgat gtggtgagcg gagaggtgct cttttcctct ttggataaat tcaattctgg
     3301 ctgcggctgg cctgcatttt ctaagccgat tcagcatcgt atggtaacca atcaccatga
     3361 ttcatcacat ggcatgcggc gtgttgaggt taaaagccgc gaggctggct cccatttggg
     3421 gcatgttttt aatgatggcc ctaaggaggc aggaggctta cgctattgca ttaactccgc
     3481 cgcgctgaaa tttatcccct atgatcaaat ggagcaagag ggctacgccg aatggttagg
     3541 gatttttgat aagagctagg aattgctagc ggccaatgaa aaggtagagc tcttagccaa
     3601 tgctagtggc taaatcaaag aaataaaaag gtggctaaag tacatagaaa aaagaggtaa
     3661 gcagattggc aggtggtcaa tctgcttttt gtgaggagac tttcagcctg ctttgcgcta
     3721 aaaagtatga aaccaataaa ccacctacta tgcgggtgtg tgtcggtggt tagcttaagt
     3781 tttttcagtt cggttttaca agcttctcta aaaggactat aatagctaat ggaaaaggag
     3841 attcatatgc taacatcttt agaaaaatta ccgggcgttt tactgtgctt gctgttagca
     3901 ctgcctgcct ggtatttggg aagcttattt cctattattg gagcgccagt ttttgctatt
     3961 ttattgggaa tgctattggc gcttgtctat cagaagcgtg actacactaa atctggaatc
     4021 gcattgacgt ccaaatatat tttgcagctg gctgtggttt tcttgggctt tggcttaaac
     4081 gtgacacagg ttttagtggt tggcttgcaa tccctgccga ttattgtagt aacgattgtg
     4141 actgccttgg gcataagcta tttgttcaaa agatggttaa ggctaccagc caagacagct
     4201 atcttagttg gtgtgggctc gtctatttgt ggtggctctg ctattgcagc cacagctcct
     4261 gtcattgatg cgcaggacga tgacattgcc aaggccattt cggttatttt tttgtttaat
     4321 atcttggcgg ccttgctatt tccagctttg ggtcagatgc ttggcttatc aaatcatggc
     4381 tttgctattt ttgctggaac agcagtcaat gatacctcat ctgtaacagc tacagcgaca
     4441 gcctgggacg ctattcacca gtctaatacg ctagatgggg caaccattgt caaattaacc
     4501 agaacgctgg ctattattcc cataacactt ggcttatcta tttaccaaac caagagcagg
     4561 caggcacata cgacagaggg ttcctttagc ctcagaaagg cttttccgac ctttattgtc
     4621 tttttcttgc tagcttcctt gataaccacc tttgctgcta gcttaggtct gccaatggca
     4681 atctttcatc agcttaagct actctcaaaa ttctttatcg ttatggccat ggcagcgatc
     4741 ggacttaata ccaatctagt gaccttagtc aaaactggtg gtaaggccat tttgctgggt
     4801 gggatttgct ggctagcgat cacatcagtt agcttagcaa tgcaggcagc tttggggagc
     4861 tggtaactga tgagaatagc tggtgatacg ctgctttata ggaaaagcaa agcccttgct
     4921 gctcctaaaa aagcttgtta gagcagctca cttagctgtt aagtgtggct tggtggggtg
     4981 taagtaggct ctatcagtta gaaaagccat cagaacaaac gctatcatta agctgaagcc
     5041 ggggaaactc ggcttttacg ttatgcagaa ttgtctacat attgaatagg attatccatt
     5101 ttaaaaacgt tttcatttga tagaatacaa ttatagcttg gttattaggg taaacgagat
     5161 tgaacttctt atctggttta gcttaagtaa aaaagcagtt ggaggaagca tgaaacgtaa
     5221 atttttaatt ggtagtcatg ggagaatggc cagtggattg aaaagctcta ttgacatttt
     5281 ggctggtaga ggtcaggaat tacaagtcat tgacgcttat attgatgata gtgattatac
     5341 tgagcaggta ttgaccttta tcgaagatgt agcagctgac gagcaggcac tgatttttac
     5401 agatttatta ggtggcagtg ttaatcaaaa aatagtaact gccctaatgg acagtggcaa
     5461 ggaaaatatc tttttgattt caaatagtaa tcttgcagcc ttgctatcgt tgatgttttt
     5521 aaagccagaa gaagagctga caaaagacga gattgtagca acgattaacg attctcaggt
     5581 gcagctggtg gatctagctc cagcgacagc cgcagaagat gactttttta attgaggagg
     5641 aaaaatgaaa tgattacaca aattcgtgtt gacgacagat tgattcatgg acaggttgct
     5701 gttgtttgga ccaaggagct taatgcccct ttgcttgtgg tggctaacga tgaggctgct
     5761 aaaaatgaga ttacacaaat gactctaaaa atggcagttc ctaatggcat gaaattattg
     5821 attcgctctg ttgaggactc tatcaaggtt ttcaatgatc cacgcgcagt ggataagcgt
     5881 atttttgtca ttgtcagctc gattaaggat gcttgccaga ttgcaaagca ggtgaaggac
     5941 ttagaggctg ttaacgttgc aaatgtaggg cgctttgaca agtcagaccc agcaactaag
     6001 gtcaaattgg cttcaagcct attgttaaat ccggctgaat tagaagcagc aaaagagctg
     6061 gttagcctgc ctaacctaga tgttttcaat caggtactgc catctaatag caaggttagc
     6121 ctgagccagc tcatcaaata aagaaaggtg taatgactat gttagtacca gcaacaatgg
     6181 cagccttagc tgtattgatt tgtttcgggg gaaattattt aactggccaa agcatgatgg
     6241 aaagaccgct tgtggttggt ttggtgacag gattgctctt aggagatatg aaggtcggta
     6301 tcttgatggg agcgtcacta gaggcacttt tcctaggaaa tgttaacatt ggtggtgtca
     6361 ttgcagcaga gcctgtaaca gcaacagcta tggcaacgac ctttaccatc atttcacata
     6421 ttgatcaaaa agcagctatg acgctagctg ttccgattgg catgctagca gcctttgtgg
     6481 tcatgttttt gaaaaatgtt tttatgaata tctttgcgcc aatggttgat aaggcagcag
     6541 cggcaaacca tcagggcaag cttgtcatgc tgcactatgg cacatggatt gtctattatt
     6601 tgattattgc ctctatttcc tttatcggta tcctagttgg aagcggacct gttaacgcct
     6661 ttgttgagca tattccacaa aatctgatga atgggctaag tgcagctggt ggtcttcttc
     6721 cagcagtcgg atttgccatg ctgatgaagc tcttatggac aaataagcta gcagttttct
     6781 tcctattagg ctttgtgttg acagcttatt tgaagctacc agcagtagct gtggctgcac
     6841 ttggtgcagt tatctgtgtg atcagctcgc agcgtgattt agagttagat gctattacta
     6901 agggagctat cagtaaccaa agcagctttg actctaaaga atcagaagag gaggacttct
     6961 ttgcatgaga tctcaagaca atttaactaa agaagaaaga aaaatgctac gctctgtttt
     7021 ctggcgttca tggaccatga atgctagtcg tacaggagct acgcaatacc acgctgttgg
     7081 ggttatctat accttgttgc ctgttatcaa tctcttttat aagacagata aggataaggc
     7141 agacgctctt gttcgtcaca ccacttggtt taatgcgacc atgcatatta ataactttat
     7201 catgggcttg gttgcctcaa tggaaaagaa aaacagtgag gatccaacct ttgacgctag
     7261 tgctattaca gcggtcaagg cttccttgat gggacctatt tctggtgttg gagattcctt
     7321 tttctggggt attttgaggg tcattgcagc tggtattggg atttcacttg ctagcacagg
     7381 ctcagcgatg ggagcagtag tctttttact tctctataat attcctgctt ttatcattca
     7441 ttattatagc ctttatggtg gctattctgt tggtgctggc tttattaaaa agctttatga
     7501 gtctggtggt attaagattg tgaccaagac ctcaagcatg cttgggtcaa tgatggttgg
     7561 ctccatgaca gcttcaaatg tgaagtttaa gaccatttta acagttgctg caaagggagc
     7621 caaggaagca gcctctatcc aaaattattt ggatcagctc tttattggaa ttgtccctct
     7681 tttagtaacc atgaccgcct tttggctttt gcgtaagaag gtgaacatta actggattat
     7741 gtttggcatt atgctattgg gtattgttct tggtctttta ggtatttgct aataatctcc
     7801 tagcatcaag gataggtaag gcagggactt cttgctttgc ttatcctttt ttgtagtgag
     7861 ggctgctgaa atagccacct gcttgcttaa atggcttatg gatttgttag atagattaag
     7921 attttcttag ctttgagaaa tgatttggta taatagaagg aaataaggga aaaggctgcc
     7981 tatggaagaa agatttaaaa agcgattgca ggatgatatt tcacatcatt tttcacacca
     8041 atcattgatt ttgtccattt tactgattgg actctttctc attttttcat tggcacctca
     8101 gcaaattggg ctgtatcaag atttgaaggc tgttgaacat agctatcacc agctgattcg
     8161 gcaaaataag gcgcttttaa cggagctcaa tcagcatatt ctgaccaaat ttgtgaatca
     8221 tcagctgagc tcttctgacc ttagcaaaca atattatcac ctaagaaacc gctcacaaag
     8281 ccaatcagag ctgctggttt ttgatgctaa cagtcacatg ctgtttgcta gtaatcagca
     8341 tctgggaaat ttttttcgca atgctgtcta tatgacagaa gtcttaaaaa aagcaaggca
     8401 aaggagtagc ttcttgagga tcagtatgga taatgaggag gggcattatt tactgctgat
     8461 aaagcctatt aagatagatc atcaggttaa gggctattcg cttcttgtga tgaatggtaa
     8521 ggattttctt cagctatcac atcagattgc ttcagatttt gtgattgcag atcagtttga
     8581 caatagcttt gcctttacca atcggacctt tatgacctca agtctgaata agcttgacag
     8641 tcattttctt aagggctatt ttatctttca cgagcatcgt gcctttatcc taagaaaggt
     8701 cgctcttagt ccttctatca ctctttacag ctaccgccct ttgattccag tttctattgc
     8761 actcttgttt tcattgatgt cctctgtcat gatttatgct attttgtatt ggaagtctaa
     8821 ggctctggcg acgcagattg cttctagcaa ttcagcagcg atcaatcaga tgattcttga
     8881 tatgcaggcc atctcaaggc aggaaaaaaa tgccattgac ctgcaaagtc aagatgaatt
     8941 tcaatacctg tcggttcaga tcaatcagat gattagccga ttgcaggcac ttcatcagaa
     9001 gaccctagcc ttagaaaagc aaaatgtgag ttttgaaaaa cgcatgctgg aagcccaatt
     9061 taaccctcat tttctctata atacacttga aacaattttg attacaagtc attatgacag
     9121 tgacctcaca gaaaaaattg tccttcagct aaccaggctg cttcgctata gcttagacga
     9181 atcacaggag gctgtgtgtc tgggagagga tttggctgtc ttagaatcct atctgttgat
     9241 tagccagatt aggtttgaag agctgcgcta cacgatagct gttgaaccag ccctagagac
     9301 cctaagggtt cccaaattat ttttattgcc attgattgaa aatgcgatca aatatggtct
     9361 gcgctatcgc catgaccttg tgattgagat cagcgtgaga cagcttgctg atggaattta
     9421 ctttactgta gcagataacg gtcctggaat tagtcaaaaa aggcaggccg atattaaaga
     9481 gctcttgcat tcagaggatt cacatcatgg cttggtcaat tcttatcgtc gactcaagca
     9541 tcaatttata aaagttgaat tgatcttttg tcaaagagat gagcgctttt tactaaccta
     9601 tatggttaag gagtaacaga tgtataagct actaattgtt gaagatgagc atattattcg
     9661 caaatggctt cgttatgcga ttgattatca tgcgctcaat atccttgtta tcggagaagc
     9721 taaggacggt cagcaggggg ctaagctgat tgcagaggct aagccagata ttgttttgac
     9781 agacattaac atgccgatta tgactgcctt tgagatgttt gaggccacaa aagagcagtc
     9841 ctatgctaaa atcattttgt ctggctatgc tgatttcgct aatgcaaagt ctgctatcca
     9901 ttatggtgtg cttgagtttt tgaccaagcc cttggaaagg caggccttac atgattgctt
     9961 gctaactatt atccaaaagc tgcaacagca gtctcaagag caggagctaa gccagcagca
    10021 ggattacctc aaactgccac agcctaatga ccaattgcct gatgttgtcc aagaaatgct
    10081 cagctggatc catgagcatt accaggataa aatcatgatt ggtcagttgg ctcacgatct
    10141 gggctatagc gaaagtcacc tctatcattt agctaaaaaa tacctgaaaa tgacttttag
    10201 tgactatatc aaccaatacc gcctgaatcg agcaattcaa ttgctgattg ctgagccgga
    10261 tgtgatggtt tatcagcttg cagaggctgt tggcatttat gactaccgct attttgatcg
    10321 tgtgttcaaa aaatatttag gacaaacggt caaggatttc agagaaacgg tattacacca
    10381 gagatcagat aggagttcat tgtgacaaga aaaaagctgc tattagcaat ggcaatagtg
    10441 atactaggtg tgattggctc tggcttgtat gctatctgga ggcatcaagc aggaccagct
    10501 cccagcaaac caagagaatt ggttgttttg acacccaaca gtcaaaatat cctaacaggt
    10561 acgatcccag cctttgaaga aaaatacggc attaaaatcc gtctgattca aggaggcaca
    10621 ggccagctca ttgatcgctt gcaaaaggac aaggaccagc tccatgcaga catctttttt
    10681 ggggggaatt acacacaatt tgagagtcat aaggagctat ttgagcctta cctttcaaag
    10741 catattggct ttgtattgcc tgattacctg ctgcaaagcg aggtcgcaac cccctatacg
    10801 cttaatggaa gtgttctcat tgtgaataat gaattggcaa aggacatggt tattaccagc
    10861 tatgaggatt tgctaaagcc agagctaaag ggaaagattg cttttgcaga ccccaacacc
    10921 tcctctagtg ccttttctca gctgaccaat attctcttag ccaagggggg ctacactaac
    10981 cccaaggctt ggagctatat caagcagttg attcatagca tgaattcaat caaatctgct
    11041 agctcatcag atgtttatca gtcagtagca gaaggaaaga tgaccgtcgg tcttacctat
    11101 gaggacccct gtgttaacct tttaaagagt ggtgccaacg tttctattgt gtatccaaag
    11161 gagggaacgg tttttttacc ctcagcagtt gccattgtta agcaatctaa ggccaaggct
    11221 gatgccaaat tgtttattaa ttatatgttg tctttagatg tgcagcgggc ctttggtcaa
    11281 tcaaccagta ataggccaat tcgaaaggac gctaaggcca gtcaagacat gaagccttta
    11341 gatgacatta tcacgctaaa ggaagactat gattatatca caagacataa aaaggatatt
    11401 ttagaacgat acaatcaatt gagaaagacc actgactaaa tggctttgtt atatgaaaca
    11461 gttcatgctg tgctgcacct gaatcgttag ctgctttgtc tagctttttg aggtcaatct
    11521 ctgcttgggc tgttttttat gttaccataa cccactgcat ttgtttagaa agtcaagcga
    11581 gatcttaata gccagttata ataggtcttt gagagggagt ctgagcttgc ttgaggtggc
    11641 aagaagatct gttttgacgt caaatggctg aatttttggt aaaatgatag catgaatgaa
    11701 ctgataaaac acaagctaga gcttttgcca gatagtcctg gctgttattt gcataaggat
    11761 aaggctggca ctattattta tgttggcaag gccaaaaatc tgagaaatcg cgtacgctct
    11821 tattttcgag gaagccatga taccaagaca gagctgttag tttctgaaat agctgatttt
    11881 gagtttattg tcacaggatc aaatacagaa gcactcttat tggaaatcaa tttgattcaa
    11941 gagaacatgc ccaagtacaa tatcaagcta aaggacgaca agtcttatcc ctttatcaag
    12001 atcactaacg agccatttcc aagactatta atcacacgtc agattaaaaa aaatgacggc
    12061 ctgtattttg gtccctaccc agatgcttac actgccactg aggttaaaaa gctgctagac
    12121 cgtatttttc cctttaaaaa atgcaaaaac cctgttaaca aggtctgctt ttactatcat
    12181 ttagggcaat gtcaggctca cacgatttgc catacagaca aggcttattg ggacagcttg
    12241 gttgctgatg tcaagcagtt tttaaacggt aaggacgaca agatcattga tgatttgcgc
    12301 tccaagatgc ttgaagcttc gcacaatcaa gaatttgaac gggcagctga atatcgtgat
    12361 ttgatttcag gtattgccac catgcgaacc aagcaaaggg tgatgagtaa ggacttgcag
    12421 gatagggata tttttggcta ttttgttgat aagggctgga tgtgtgtgca ggtctttttt
    12481 gtccgtcagg gtaagctcat tcagcgagat gtgaatatgt ttccttatta caacgaagct
    12541 gaagaggatt ttttgaccta tgtcgggcaa ttttatagcg accaacggca tttgatccct
    12601 aaggaggtct ttattccaga gacgattgat gagaccttgg ttgcagccat tgttccagca
    12661 aggattgtca agccgcagcg aggggaaaaa aagcagctgg tcgccttagc aactaagaat
    12721 gctcgggtta gccttcagca aaaatttgat ttgctggaaa aggatttaag aaaaacaagt
    12781 ggtgctattg agcatcttgg tcagctgtta ggcattgaaa agcctgttcg tattgaggcc
    12841 tttgacaatt caaacattca gggcacaagt ccggtagctg cgatggtggt ttttgtcgat
    12901 gggaagccca gcaagaagga ctatcgcaaa tttaaaatca aaacagtgat tggtccagat
    12961 gattatgcga gcatgagaga ggtgatttat cgtcgttata gccgcgtgaa gcatgaaggg
    13021 ctacaggcac ctgatttgat tattgttgat ggtgggcagg gtcaggtcaa ggctgctcgt
    13081 gatgtgattg agcaccagct aggccttagc attccagtag ctggtctgca aaaaaatgac
    13141 aagcaccaga cccatgaatt gctttttggt aaccccttgg cagtggttga gctgccgaga
    13201 aattcagaag agttttttct gctgcatcgt atacaagatg aggttcatcg ctttgccatt
    13261 acctttcaca ggcaggtcag gagtaaaaat gccttttcat caaagctaga tcacattgca
    13321 ggcttagggc caaaacgcaa acagctacta ctcaagcgat ttaaaagcat gactgctctt
    13381 gaacaggcta gtcttgaaga aattcagcag ctagggattc caaaaacagt cgctgaggca
    13441 ctgtttgatc accttacctc aaaaagtgag gtctgaattg gccttgtcag gagctcaagc
    13501 agtctgaatt ttcttgacaa aagtgaaaaa atagctgaaa ccagtttcaa aaaatgatag
    13561 aatgatacta caacataaaa gaattagata ggaagcattt gcagtgaaat ttctcgaatt
    13621 aaacaaaaaa cgccatgcta ttaaacggtt taacgataag cccgttgatt ataatgactt
    13681 gcgaacagct attgaggttg ccactctggc accaagtgct aacaatattc agccttggaa
    13741 atttgtcatt gttgaggaaa aaaaggcaga gctggcaaag gatctgccgt tggctaataa
    13801 gactcaggta gagcaggctc agtatgttat tgccctgttt tctgataccg acctcattca
    13861 gcgctctcgt aagattgccc gcattggggt caagtccttg cctgataact tgattggtta
    13921 ttacatggag accctgccgc cacgttttgc tacctttact gagacccaaa aaggcgaata
    13981 tctggccatt aatgctggct tggtggcgat gaatttggtc cttgccttaa cggatcagaa
    14041 aatggcctca aatattattt taggctttaa taaaaagcta actaatgaga ttttagatat
    14101 tgatccacgc tttcgtcctg aattattgat aactgtgggg tatagcgatg acaagccaga
    14161 gcctagctat cgcctaccag tagacgaaat cattgaaaga cgctaagata cacaactact
    14221 cgtccagcta gcctataagt ttttggattt aggaggatag cgaggcaaca cataaaggag
    14281 aaaaagatga caacaattga ttttaaagca gaggttgata agcgcaagga agctatgcta
    14341 gaggatctat caaacctatt aagcattaat tccgagcgag acgatgctaa ggcagatgcc
    14401 aagcacccat ttggtcctgg tccggttaag gccttggagt tctttcttgc catggcagag
    14461 cgtgatggtt accaaacgcg taatattgat aactatgctg gtgattttga atttggtcag
    14521 ggagatgagg ttttagggat ttttgcccat ttagacgtgg tacctgctgg tagtggctgg
    14581 gagacagacc cttataagcc ggtgattaag gataatcgta tctatgcgcg tggttcatct
    14641 gatgataagg ggccaaccat ggcttgctat tatgccctga aaatcatcaa ggaattaggc
    14701 ttgccagttt ctaaaagggt tcgcttcatt gttgggactg atgaggagtc aggctggggt
    14761 gatatggact attattttgc tcacaatggc ttgaagaacc ctgattttgg tttttcacca
    14821 gatgctgaat ttcccattat caatggtgag aaaggaaaca ttacagaata ccttcatttt
    14881 gttggtcaaa atgctggagc ttttgtcctt catcgcttcc aaggcggttt acgtgaaaat
    14941 atggttcctg aatcagcgac agctctgatc agctcaccgc atgagcttaa tgttatcgaa
    15001 gcttctttgg agcaattctt atctgagcac gcagtgacag gatctgtcaa agaggctgat
    15061 gggctattgg aagtgaccat tattgggaaa tctgctcatg gctctacacc agaggctggt
    15121 gttaacggtg caaccctgct ggctaaattc ttaaatcaat ttagctttga tggcgcagcc
    15181 aaggcttatt tgcatattgc aggtgaggtg cttcatgagg atttcacagc agaaaagctt
    15241 ggcttggctt atacagatga caaaatgggt gcccttagca tgaatgcagg tgtctttagc
    15301 tttgctaagg attcagatga caataccatt gccttgaatt tccgttatcc aaagggaacc
    15361 aatgcagcag tgctaaaggc agggcttgag caattaccag gcttgactaa ggttacctta
    15421 tctgagcatg aacacacccc tcactatgtg ccaatggacg atgagctggt ctcaaccctc
    15481 ctatccgtct atgaaaagca aacaggactc aagggctacg agcaggttat cggtggtggc
    15541 acctttggac gcttgcttga gcgtggtgtt gcctttggtg cgatgttccc aggtgatgaa
    15601 aacacaatgc atcaggccaa tgaatacatg ccattagaca atatttaccg atcagctgcc
    15661 atttacgccg aagctattta tgaattgatc aaataagaga ttgaacaagc tctctgtcta
    15721 agatgagcct tgctaatatt aacgaataaa agccttatga agttagtcgt ttaatgagac
    15781 ttcataaggc tttttgtttg gcgtcaagcc attatttaca aagagaaatg ccacagtgga
    15841 tcatcttttg aaaagtcctt gtaaaaacag acgtaaaact agttttagag gagacattga
    15901 taggcagtca tgcttatcaa gagatcttgt ctagcagtta tggcaaaaag atcagtgaac
    15961 tattattttc caaggcagaa ctgactgaac aattgagtaa ttaattcatc aggtgcggca
    16021 tcgcctgtga tttctcctag gatttcccaa gctctggtca aatcaatctg taagagatca
    16081 accggcattc ctaaagcaag tccttcattg acagcctcta agctttgtac tgcctgctca
    16141 atcaaggaaa tatgacgagc attggatagg taagtcgcat cttgctctat tagcccagta
    16201 tgatcaaaga aaatctgatt gatccggtct tcgatcaggt caatgttttg gttttgcaaa
    16261 actgatattg ggatcgcctc ttctggaagc tggtcttttt caatgacctg ctccagatcg
    16321 gttttattga ggagaataat gcgattgcta tcctgactaa gggctagcag agccttgtcc
    16381 tgttcggtca gcttttccga agcattgaga actaaaagga ccagatcagc ctcctgtagg
    16441 gcttttttag accgctcaac accaatttgc tctactaaat catctgtttc tctaattcca
    16501 gcagtatcaa ctagctttag aggaattccc ttgatattga catattcttc aatgacatca
    16561 cgagttgttc ctgcaatatc agtgacaatg gccttatcct cacgtaacaa ggtattgagc
    16621 agactagact ttcctacatt cggtcggccg ataatagctg ttgacaagcc ctcacgtagg
    16681 atcttcccgc gcttggcagt acgtaggagc tgctctaaaa gtgtttgaaa ttctcgcgtt
    16741 ttgtcacgca aaagagcagt ggtcatttct tcgacatcat catattcggg gtagtcgata
    16801 ttaacctcaa cctgggctaa ggtatttagg atttcttgac gtgtgtcgct gatgagctgt
    16861 gatagggagc cgtctagctg cttgatagca atagacatgg ccttatcagt ctttgcacga
    16921 atcagatcca tgactgcctc agcctgtgtt aaatcaatac ggccatttaa aaaagcacgc
    16981 tttgtaaatt cgccgggctc tgccattcga gctccctgtt taatgaggag ctgtaaaatg
    17041 tcatttgtca ccgcaatacc gccatgggta ttgatttcaa tcacgtcctc tctggtaaag
    17101 gtttttggcg ccagcatgac tgataccatg acctcatcaa tcacttcacc tgtgcttggc
    17161 ttgataatat gaccatagtt aagggtatgt gaggcgactg ttgttagatc ttttccttta
    17221 aagatcgatt tagcaatgtc cagagccttg gtaccagaca agcgaacaat gccaatagct
    17281 ccttcaccta acggagttga aatggctgca attgtatcaa attctttagt tatactcatg
    17341 ccttctattg tagaacaagt cagcatagaa agcaaggtat tgcattagct gctcgttgtc
    17401 gtcattcttg tctagtggca aagcctcaaa agcagttgta aacagctaaa gctatgatta
    17461 aaaagccttg tatggtaagt acaggataaa gccaaaaagc tgatgagttt tagataaaca
    17521 tacaggctcg aaaagcccta ttaaaccgac agcaacaatc ctcacacagt atagttgact
    17581 taactacctg atgtcatttc tggctgtttt tataatgaca atggcaatat cggttatttt
    17641 gactatgctg ggtgcttgta tcctagtgga ctgactgaca atcagggctt ctttttcaac
    17701 cacgaaaaca ttaaaaaagt ctggtttgga ggctatattg acgatagtga aagagaagct
    17761 caagactttt ttaaaaaaga ggcaggctat attaaatatc ctaaacttag tatagataat
    17821 agcactagat agcattaatt taagtatata acgttatgat tatggttgga ttagttcatt
    17881 atacactagc aataaggtag attattttgt tataataaaa tatatacaat tattagagag
    17941 ttagaaagag ttatatggta gtattacaaa ataatagtag cacagctagt gagcgagcga
    18001 cagctttggc aagaggagtc caggccctct ctagtgctgg tgcggtgagc aaagatatga
    18061 agacgaccgt tactggaaat cgtagtgatg ccagctctgc cattgattta tcgcacaacg
    18121 tttcagcgca ggtagttggg atcatcgctt ctatgtcgca acacattcag agtgtctctg
    18181 cctcttttca agcgatggat cttcagcttg gaaaagagtt agggcgttta gaaaacaggc
    18241 ggaggtttag tctcaatgac ccaaaatgag ctcatgtacc agaaggagag attggataaa
    18301 cgcttggaaa ccatagccca agagcttaag cgtaatgaac agcgctttga agactatgag
    18361 gaactatcta acctagcggc acaactgtta acagcagctg caaccacctt tcgttcatca
    18421 tcagatagtc atctctttga aggggctttg gcagaagaat gttatttgaa aaggaaaaca
    18481 caagcgtcct tggaacaaag tcatgaggag ctcttaggag agcagcgtcg tttgtaccaa
    18541 gaagaggaag ccctcacccg acaattaaag ctagtcaaag gaaaggagag agctaatgag
    18601 cattgacatg tatctggggt catcggacca gcaagctagt agcgttggta aggtcttgca
    18661 gcagcggata acagcttata agtctttgca aagagctttg gagcaattgg tgtcttctag
    18721 tcctgactta tcagggcata cctatgcttc tgctaaaagg tacagcgagc aggtattgat
    18781 ccctttgatg aggggctgta tcctgctaga tgaagccatc aaggaagcct gtgcagcatt
    18841 tcctaatgac taccgtcgtc aggttgatag tgtggatttg aaggagagtg agctggtgga
    18901 tcagatcagc cgctcagacc gcatcatagg tcgttacgtt gagttgattg atctggagta
    18961 tcggcaggag ctgccgaatt actcttatat tactaatctc aagagcggag cgagtaacca
    19021 gcgtcaagtc aagagaaaat tagaagagaa gctccttaag ctgcgagagt ttgatagcaa
    19081 ttcccgtcac ctcttttcgt ctatcgcagc cttagccgag gcagtcaata taggtatcag
    19141 acaaaccaag acctcttgga atgggacaag tcagacgttc actcttccca gggctcttga
    19201 cttagagtgg accaaggtag tagaaaagag gtggacgcaa agggaggaaa aagcctcgaa
    19261 gctgaagcta cagcaggcag cagaaaaact ttcgagagaa accgggatta agtacgaaga
    19321 tgcctatcgt tttgtgatgg acggtgttct gtcagatgaa aataagaaca aaatcaagag
    19381 tgtaaagaaa ctagttaagt atacaaaggg tgggctgtat atcgtttcct caggaaggta
    19441 ttattggaaa cattcaggta aacattattg gaaaaataca ccaaacaaaa catggaatat
    19501 ttggaaagca tctaaaaacg atcccaattt tgacaaagga gggatcaaag gtaaacattt
    19561 ttctaaaaaa ggagcccgtt acacagactt acctggtatc aagcaattga agaagagtga
    19621 aacagtacaa tccctcattt caaaaatttc aaaagataat caagggaagc tcaccaaagt
    19681 tggtaaaggg ttaaagaaag ttgataaaga gctaagcaac atatcgtcaa aactcaagtc
    19741 atatgagcat ggacgcctaa atagagactt gaaaatgatg aaggagaata acctgggtaa
    19801 aagtctcggt aagtttggga aagttggaaa agctgcaagc aaggtgctca agtttgcagg
    19861 aaaaggtctc aaagttgcgg gttgggtagg tgctgctata aatgttaagg actcggttga
    19921 aacttacaag aaaaaaggct atagcaatga gcaaactgct gctttaacag cccgtaaggt
    19981 agctgttgat actgcaacaa ctgttgtcgg aagcaatatt gggcgtgtaa caggtgcagt
    20041 tattggtcaa gcagttatac ctattccagg tgtaggtgct gctatcggtt ctgttgcagg
    20101 aagtatttta ggagctatgg caggtagttg gattggtagt acaattaatg acaatttaga
    20161 taagaacgta aaacctaaac aatcaggaag gagtttagca tggtaatgtt aatgagaaca
    20221 ctgttatttc cagttgataa cggacttgat tcaggattga ctggtgatgg ttatgcagct
    20281 gagtatgatt tgtggactgg aaaggtcacg tggcgacaac ttggtgatgg aaaaataaaa
    20341 aggcaacaaa aggtagcagc tataattaat ctcattgcag ctgcaatatc tccacttgtc
    20401 atcatgtcta tcatttttac ggcaaaaagt ctgaagcttt ttgatgtaga tactagtaca
    20461 acaatttatc gatatgctcc tctgatggta ggcttggtct ttttcttctc gtttgaatta
    20521 ttgatgctgg ctattagacg tctgtatcca ttagccaaag aggagccaag tttaaagcgt
    20581 caacatgggt attttaagac catgtatgac aatactatac gtgagaatga tggtgttttt
    20641 aataatttat cagtaccttt tatagggctt tatgtagctt tcttgattgc cttttcggtt
    20701 attccaattt tttactctca atatctgcag caaaattctt tttggtccta tttaggaaat
    20761 ttagtaggaa gtagcattct tatttcctta gtccccaatt ttttatggaa tgtcttagtg
    20821 aaacaattga tttacatcaa gcttattcgc aaaacgaaag aaaaaatctt aaagaatgaa
    20881 acctaaacaa tcaggaagga gtttagcatg gtaatgttaa tgagaacctt gttatttccc
    20941 atagataatg gtatggataa taacttaatt ggagacggct tatcagctga gtatgaccta
    21001 tggactggaa aagttacgtg gcgtcagccc agtgatgata agattagaac ccaacaaaag
    21061 gtagcatttg tacttaatct tatagctggt agtttatctc cattagctat atttttattt
    21121 gttattattg ttagacgctt aggcgttttt agtggcgata ctaattcaat gattttcaag
    21181 tgggcaccgc taatagttgg atttatcctt tttatatcgt ttgaattatt gatgttggcg
    21241 cttagaagta gatatacgat attagagaaa gagcccgatt tagatcgtca actatactat
    21301 tatcgtacaa tgtatgataa tactatacat gacaattcag gtgtttttaa caatttatca
    21361 gtaccttatg taggtctata cattacttta tttctaattt ttttaatcat tccactttgt
    21421 tatcattttt acttgcaccc atcttcattt ggggattatc tcgctgcatt atctgtaaca
    21481 agtttgttga tttccttatt tcccaatttt ttatggaatg gtgtcttgaa gcacgttata
    21541 tatgtcaaac ttattcgcca aacaaaagaa agaattttaa agaatgaaac ctaaacaatc
    21601 aggaaggagc ttagcatggt aatgttaatg agaacgctgt tattcccagt tgataatggc
    21661 atgggaacgg gcttgaccgg tgatggttat gcggctgagt atgatctatg gactggaaag
    21721 gtcacgtggc gacaagccac caaacaaaca attgaaaagc aacaagcact aacgtctaac
    21781 cttttgatta ttgcctcatg cttatcacca gttactgttg caggaatgat actgttgagt
    21841 agaagtttcc ctattttcga ggaagactta tcagagaaaa ttgatactta tgctccaatt
    21901 attcttggtg ttgtgttatt tcttgctttt gagacgttaa tgcttgctat cagaggtcgt
    21961 gatccattag cggagaagga accagattta aagcggcagc atgactattt tgaaaagatg
    22021 tttgattttg ctattcgtag aaatttgtcg tcagataatc taaaaactcc ttatatagct
    22081 acttattttg cttttggtat ttctttactc tgtattccat ttagctatta tgtttatctg
    22141 aatccggagc aattccctaa tttggattat ggtcatttat caatcctgct tgtaacaagt
    22201 attcttattt ccctagttcc caacttttta tggaatgttc tattaaagca cattatctat
    22261 atcaagctta ttcgcaaaac gaaaggacaa taaaacatta tgaacaaacc agaacacatt
    22321 ttaccgattg gtactatagt gctgacggag acaggagaaa ttcctttgat gattgtgagt
    22381 cgtgcctctc tttttgatga taatggagaa atcggctatt ttgattatgc tgcagttcct
    22441 tatccagaag gcataggaaa tgataatgag taccttttct tcaaccatga ggatattgct
    22501 gatgtcatct attttgggta tgtcaattcc aatgaacagc tttttgcaga agcctacgat
    22561 gatttggtga aaacatcagg ttatcgtaaa ttaagcttag atcaccatca atagaaaaag
    22621 gacatgaaga ttatctagaa aaagaaaaga actaatgagc attgacatgt atctggggtc
    22681 atcgaaccag caggctaatg atgtatggcc aatattttga gaggatcggc ctgctcctct
    22741 tttttgtatg ttcaaagcta taaaaagctt actttttgag gtataaagct tcgacaatca
    22801 agagtatttg ctctggtggc tttaatgatc ttgcttatag cttctggtca gattgtttta
    22861 gcctgcttgt gctgtctgat ccagatttga ctgaggcttt gatgacagtc gtgaaggcgg
    22921 gtttaagaat ggcatgtcta atgtcaattt acaatagaga aggaaaattg atcaaacagt
    22981 gtgagatatt attaacaagt ttgcgctttc atggtataat aaagtgctag gaagcatttt
    23041 attataagat aagggggaat catggaagca ctgaaaaaga ttgccggtgt gactgctgcg
    23101 caatatgtaa cagatggaat gaccattgga ttaggaacag gatcaacagc ttattacttt
    23161 gttgaagaaa ttggtcgtcg catcaaggaa gagggactac aggttgttgg tgtgacaacc
    23221 tcaagtgtaa caaccaagca agcagagggc ctaggtattc ccttaacatc aattgatgat
    23281 attgactgca ttgacctgac tgttgatggt gctgatgagg tggataaggc ctttaacggt
    23341 attaagggtg gtggagcagc tctattgatg gagaaaattg ttgcaacacc aaccaaggaa
    23401 tacatctggg ttgttgatga atcaaagctg gtggatcatt taggtgcttt caagctccct
    23461 gttgaggtcg ttcaatacgg tgctgatagg ctatttcgag tctttgaaag ggctggctat
    23521 aagccctctt ttcgcatgaa gggggataag cgtctcataa cggatatgca gaactttatc
    23581 attgatctta accttggctg tatcgaaaat ccttgtgagt ttgggcgtct gctggatcaa
    23641 actgttggtg ttgtcgagca tggccttttc aatggtatgg ttgataaggt cattgttgct
    23701 ggtcaggctg gtgtaacggt ccttgaagct aatcagtcaa cctaattcct agctcaatca
    23761 tgttttacat tattttatag gttttgggga gccaaccgta acctccccta gattggagac
    23821 ttatgtcaaa atttaatcgt attcacttag tcgttctaga ttctgttggt attggtgcag
    23881 caccagatgc cgacaaattc tttaatgctg gtgtagctga tacagattct gacaccctcg
    23941 gtcatatttc agagacagct ggtctggctg ttccaaatat ggcaaaaatt ggacttggtc
    24001 atattcctcg tcctgtcccc ctaaagacag ttccagctga ggctgatcct actggctatg
    24061 tcaccaaatt agaagaggta tctcttggta aggataccat gacaggtcac tgggaaatta
    24121 tgggcttaaa cattactgag ccatttgata ccttctggga tggctttcca gaggagatta
    24181 tccaaaaaat cgaagctttt tcaggccgta aggtcattcg tgaagccaat aagccttact
    24241 cagggacaaa ggtgattgat gattttggtc cccgtcaaat ggaaactggt gagctgattg
    24301 tttatacctc tgccgaccct gtattgcaaa ttgcagcaca tgaggaggtg attcctgttg
    24361 aggagcttta ccggatttgt gagtatgcgc gttccattac ccttgagcgt cctgctcttt
    24421 taggtcgtat tattgcccgt ccgtatatag gagagccagg cagcttcact cgcacagcta
    24481 atcgtcgtga ttatgcagtc tcaccgttcc aagacactgt cttaaataag ctggctgacg
    24541 ctgggatttc tacttatgct gttgggaaaa tcaatgacat ctttaatggc tcagggatta
    24601 ccaacgatat ggggcacaat aagtctaaca gtcatgggat tgataccctg atcaaaagct
    24661 tgcagttgcc agcatttaca aaaggtcttt cttttactaa cttggttgat tttgatgcta
    24721 gctttggtca ccgtcgtgat ccagagggct atcgtgactg tttgcatgaa tttgatcgtc
    24781 gcctgccaga gatcattgcc aacatgaagg acgatgatct gctcttgatt acagctgatc
    24841 atggcaatga cccaacctat gctggaactg accacacacg tgagtatatt ccattgcttg
    24901 cttactcagc ctcctgcact ggagcaggtg tgattccaca gggacatttt gctgatattt
    24961 cagcgactat tgccgaaaac ttcggtgtgg acactgctat gattggaaca tcattcttag
    25021 ctgacttggt ataggagtaa gcaaatatca tttgataggc caaggagctt ggcgtatcaa
    25081 attgaaaacc agcgctgtgg ttaggtctat taataggctt gtggcaggtt gtctagttct
    25141 gatgatcggt gtgatattag ttgatttatt ggactttgct acagcaaaaa gctcaagaga
    25201 agtatgcttt atagtaaaaa ataaataaga taaagggaga aataagatga cattacttga
    25261 aaaaattcgt gaaacacagg ctttcctaga aagcaagggc attgataagc ctgaatttgg
    25321 tctcatttta ggctctggtc taggtgagct tgccaatgag gttgagcagg cgattgtgat
    25381 tgattatgct gatattccaa actggggcaa atcaacagtt gttggtcatg ctggaaaatt
    25441 agtttatggt gagctggctg gtcgtaaagt attggcactt caagggcgct ttcatttcta
    25501 tgaaggtaat ccaatggagg ttgtgacctt cccggtacgt gtgatgaagg ctctgggctg
    25561 ccatagcttg ctggtgacaa atgcagcagg cggtatcggc tatggtcctg ggacgcttat
    25621 gctaatcaat gaccatatta atatgacagg aacaaacccg ctcattggtg aaaacctaga
    25681 tgaatttggc ccacgcttcc cagatatgtc tgatgcctat acagcagctt atcgtgagac
    25741 agctcgctca gtagcagaaa aactaggctt agacctgcaa gagggtgttt accttggctg
    25801 ttcaggacca acctatgaaa caccagctga gattcgtgcc tttaaggtta tgggagcaga
    25861 tgctgttggt atgtcaactg ttccagaggt tattatcgct gcccactcag gcttgaaggt
    25921 gcttggaatt tcagcgatta caaactttgc agcgggcttc caatcagagc ttaaccatga
    25981 agaggttgta gaggtaactg agcgtatcaa ggaaaacttt aaaggcttgg ttaaggctat
    26041 tttggcagag ctttaaggct tgctcttaga ctagcagtaa ccatgagcga ctgctagtac
    26101 tttgatcgat aagacgagga aaaataagga ttgggacatt agagtgatga ctgatatgga
    26161 acatacgata agtattcttt tagaagttta tgcttatagt catgcctaca aaattgcaag
    26221 aactctgcct gatttttccc ccaaggtact ttatttgctt gagcttttaa aggaaagaag
    26281 agagcttaac gttgcttatg cctttcaaca tagggcggaa aataggctta ttgaggatag
    26341 acatcaggtt aagcttttgt taaatgaagc tcaagaggag gagcagactg caaattacct
    26401 gcttgatttg gcagctaagg tcaaaaacgg tgagattatt gattttgtaa ggtcagtatc
    26461 gcctgtcttg tatcgtctct ttttgcggct gcttgagcag gctgtcccag atgttcaaag
    26521 ctatattatt gataccaaga atgatcaata tgacacttgg aattttaagg cgatggaaaa
    26581 agccgataat gacctcttta ggagctatct ggcacaaaga cagccacgtc atgtgacgac
    26641 acgcagcttg gctgatttac ttgttttatc agagcttcca gctgatatta aaagactagt
    26701 ggtagtctta aggcagtttg aaaaatcagt ccgcaatccc ctagcacatt tgatcaaacc
    26761 ctttgatgag gaggagctat atcggacaac tcatttttcc tctcaagcct ttctagatgg
    26821 tttgattcgc ttagcagttt tttctggtgt taactatatc aaagagccct tctattttga
    26881 tgtcgttaat gctgtcattg aaaaggagct gttagacagc gccaagcctt agctatttga
    26941 aagattagca ataataaaaa acctgaacga tctgaacgag gcttctctaa gctagctatg
    27001 actagtcagc ttagagcctt agaacaggtc tttcaggttt tttatgttta gctagtgtgg
    27061 ttaattaatg attgaagcta atttcttcta gcaggtagtc aataaatcgc tctcccattt
    27121 ttgagaggtt agccttttcg tgcttgataa agacaatctc aatcacatca gggacatcta
    27181 agggaatagc gacaatctgg tctccattta gatttgtgtt taaaataccg ctggcaacgg
    27241 tgtagccatt taagccaatc atgagattaa atagggtagc tcggtcactc accacaatag
    27301 acttactgtg agggatatgt gccatcatct cctctgagaa ataaaaggaa ttgtgaatcc
    27361 cctgatcata gcttagataa ggaaaatcaa ggagatcatc aatggttaag ctggttttat
    27421 ttgccagagg attggacttg ctgataaaga tatgcggtgt ggttttaaat agggtggaaa
    27481 cggtcaaatg attttcctca aacagcttgg taaggacgtc tcggttgtag tcattgataa
    27541 acaaaacgcc gatttctgag cgaaaatttt tcacatcgtc aatgatttcc caggttcttg
    27601 tttctcgcaa gaaaagctcg tactgggtca tatcagcccg ctttaataaa gagacaaaag
    27661 cattgacaac aaaggcgtaa tgctgagagg aaacactaaa gagctcacga ctagtattgt
    27721 gatttttata gcgatcctct agcagtgctg tttgttcaat aatttgtctg gcataagata
    27781 gaaactcaac cccgtccttg gttaaggtaa tgcccttggg attacgaatg aaaatagtaa
    27841 tgcccatctc ctgctctaat tccttgacag cattagacag actgggctgc gtgataaata
    27901 attgcttagc ggcttcgttc atggaaccgc attcaacaat ctttataatg tattgtagtt
    27961 gttggattct catactgaca gtctatctta aatagtacaa agaatcaagt gcctttatta
    28021 gagcttaaga caaggtttca caagcggtag cctagcttgt gcggtgaagc tagcttgatg
    28081 ctagtgttgt acccaggtaa aaaagagctg gcaaataggc agttttatcg ctttttaccg
    28141 cttatttttg gcatgcctgt gttttgataa acggctggtc ttgatcggta aaaagtaatc
    28201 gtgataatgt cagataatac ctatttttcc attgctcttt taattttctt gtgttatatt
    28261 aataatattg atatatttaa tgttttgaga taaagggtgg tgatggtgta atatgactgg
    28321 acaaagtagt catcaggtat taattcaaaa gctgttggtc agcactcact atttgacatt
    28381 atttagagat gagctgaagc tagttgagag gacaccatct attttgggaa gtgagtttcc
    28441 tgtctctctt gttcaaacgg aattaggtga tattatcacc ttggtggata ccttaaataa
    28501 gcagcagcgc ttgattgagt cgaccttttg gtatgaggag tcagccttta agctcatgaa
    28561 caaggcctta gatattgttg ataattggat aaaggggata gatggcttaa ttaagctctg
    28621 ccagtccaag gaggtctttc aggccattgt tggtgataaa agaacacgtg tttttggtgt
    28681 tttgattgat gttttttctt ccctaaaaat tagcaccatg tcattgaagg aatttgcagc
    28741 tccggctgct ctttgccatt agattaagct gggctaagct tggatagtgg ctggttaagc
    28801 ctgcaagttg cccctctcat gacaagtcta ggctttattt agggtgagca gtgtgccaag
    28861 ggtgtattaa gtgctggttg ctttgaagct tcgccttgct aggttagctg tgagtgatgt
    28921 cacgataact gcgcgaaaca gttatttctg aattataata caggttaaag taggtacttt
    28981 taat
//
LOCUS       DARYXW010000017        27917 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.017, whole genome shotgun sequence.
ACCESSION   DARYXW010000017 DARYXW010000000
VERSION     DARYXW010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27917
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.017"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(290..2080)
                     /locus_tag="TV191_000607"
     CDS             complement(290..2080)
                     /locus_tag="TV191_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HEL1507144.1"
                     /translation="MTHLVDLRKKPYSLDEEAICWVEDTIAAMTLEEKIGQLFVNMGA
                     SRSEDYLTQVLEDYHIAAVRYNKGMASEIWDQNYILQTKSKIPMLIAANTEAGGDGAV
                     NDGTKVGDEIKVAATNDPKYAYEMGRIAGLEASAVGCNASFAPIVDLTRNWRNPIIAN
                     RNWGVNVDQIIELSKEYMKGIMEYGIMPFAKHFPGDGIDERDHHLSFASNPMTKEEWL
                     SSFGRIYGELAEAGLPGIMAGHIHLPNVEKAMHPERELDDMLPASLNKTLLDELLRGE
                     LGYNGAIVTDASHMVAMTASMPRRLLLPTAIEAGCDLFLFFNDPDEDLQWMKEGYEAG
                     ILSDERLHDALRRTLGLKAKLGLHRFEGHREDIMLPKDKAMVLINTPEAQAIADEVAD
                     KAITLVKNKQAGIFPVTPERYKRVLIVNVEGYKGGFGAMIAGQKKRASDIVKELLEAR
                     GHEVTVWESTEERIMQLPEEERAAAIANVYAQKQPISNITEHYDLILNLVDVNSGGTV
                     QRIIWPAAKGTPDQPFYVHEVPTIVVSVQHAFALADMPQVGTYINAYDGKDNTMKALV
                     AKLAGESEFTGVSPVDAFCGLIDTQLWHSF"
     gene            complement(2195..2998)
                     /locus_tag="TV191_000608"
     CDS             complement(2195..2998)
                     /locus_tag="TV191_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEL1507145.1"
                     /translation="MTAKTEQFVFCVDSDGCAMDTMTYKHQLFFGPLAADYFAVADQA
                     SFLKEWDRINLYSRTRGVNRFVGLVMGLEYAGVTGIDALKQWVQHTASLSNQSLEAEL
                     LKRPSDDLQKALDWSNEVNRQIEAYKGEALAFLGALAALKALHQLGQVFVVSSANKEA
                     VQKEWQDQGLMTHVDGLYCQDRGKKEAVIAQLIDEGYVRERMMMIGDSPGDLAAAEQN
                     QITFFPILVGKEASSWQDLSHAAEAFTTGDLTELDVKSLTEAFWRNLDR"
     gene            complement(3262..4101)
                     /locus_tag="TV191_000609"
     CDS             complement(3262..4101)
                     /locus_tag="TV191_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEL1507146.1"
                     /translation="MSRVIEFKDKVVVITGAGGVLCGSMAKAFAKAGAKVALLDLNQE
                     AAQAFVDDIEAEGGIAKAYQANVLSKENLEAVRQAVLADFGPADILVNGAGGNSPKAT
                     TDNEFHDTSLPEDTKTFFDLDEAGISFVFNLNYLGTLLPTQVFAQDMVGRKGANIINI
                     SSMNAFTPLTKIPAYSGAKAAISNFTQWLAVHFSKVGIRCNAIAPGFLVTNQNRSLLF
                     TEDGQPTARAEKILKNTPMGRFGEAEELIGGLFFLADEQSASFVNGVVLPIDGGFAAY
                     SGV"
     gene            complement(4117..5211)
                     /locus_tag="TV191_000610"
     CDS             complement(4117..5211)
                     /locus_tag="TV191_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HEL1507147.1"
                     /translation="MKMSFRWYGKHDPVSLEEIKAIPGMQGIVTAVYDVPVGQAWPLE
                     NILELKRIVEAAGLEISVIESIPVHEDIKQGKPNRDELIENYKTSIINVGKAGIPVVC
                     YNFMPVFDWTRSDLNYPLPDGSTSLAFLKADLADVDPVADDLNLPGWDFSYSKEEMKA
                     IIEHYRHHISEEDLWANLDYFIKAIMPTAEAAGVKMAIHPDDPPYGIFGLPRIITGQK
                     AVERFLDLYDSPNNGITMCVGSYASDPQNDVIAMTEYALKRQRINFMHTRNVTAGDWG
                     FQETAHLSQAGDIDMNAIIKLLVDYDWQGPLRPDHGRRIWGDQTKTPGYGLYDRALGA
                     TYFNGLYEANMRAAGKIPDFGITVKTVGDK"
     gene            complement(5473..6870)
                     /gene="uxaC"
                     /locus_tag="TV191_000611"
     CDS             complement(5473..6870)
                     /gene="uxaC"
                     /locus_tag="TV191_000611"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HEL1507148.1"
                     /translation="MAFNDDNFMLKNEAAKRLYQQIKDQPIFDYHCHLDPKEIFEDKV
                     YDNIVDLWLGGDHYKWRLMRANGISEEEITGSASKLDKFKAFARTLQRSYGNPVYHWS
                     VMELKNVFGVCELLTEDNAEEIYHRINAYLVEHQISPRKLIADSRVRFIGTTDHPLDD
                     LAWHKRLAADDTFETVVAPTFRPDEAFIEHQRFADFVARLAQATGRTITDFKSFIAAM
                     EERIAYFAENGCKASDISFTEIVFEAAEPEQLDRLMTRVLEGYQPQPLEVKQWQTAVF
                     AELCRLYKHYGFVTQVHFGALRNNHSAIFNKLGADVGVDSLGDQTGLAINMNRLLDHL
                     VQRDSLPKMIWYNLNPSYNIAVANTLANFQANENGIAGYLQFGAGWWFADTKLGMISQ
                     MNALAEQGLLANFVGMLTDSRSFLSYQRHDYFRRILSTYLGEWIEEGEVPEDYQALGK
                     MAQDIAYNNAIQYFN"
     gene            complement(6898..7515)
                     /gene="eda"
                     /locus_tag="TV191_000612"
     CDS             complement(6898..7515)
                     /gene="eda"
                     /locus_tag="TV191_000612"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEL1507149.1"
                     /translation="MLNRLKENYFFAIIRGKTVEDAIAIAKHAILGGIRNIEITYSTP
                     NASEVIRILSAEFEHDDAVIIGAGTVMTPDLAREAIAAGASFLVSPHFSREIAEVANQ
                     ASNLYFPGCATATEIVTAMNASCPIIKVFPGGVVGPGFIKDIHGPIPEVDLMPSGGVS
                     IDNVKEWKNAGAVAVGIGSALASRVEAEGYDSVTRIAASFVSALD"
     gene            complement(7698..8369)
                     /locus_tag="TV191_000613"
     CDS             complement(7698..8369)
                     /locus_tag="TV191_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000113633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HEL1507150.1"
                     /translation="MARPLVEKTAERLLKLILERGYEVGAKLPNEYELAQDLEVGRST
                     IREAVRSLATRNVLEVRQGSGTYISSKKGVSEDPLGFSLVKDTAKLTADLFELRLLLE
                     PRIAALTAQHATPKEVEALEKLVVDIEEAVAAGDPKHLQLDVNFHSLMAKYSGNIAMD
                     SLLPVINQSIHLINANYTNRQMKEDSLQAHRDILNAIKAGDPIAAHDAMLLHIMTVKR
                     TAFLS"
     gene            complement(8411..10201)
                     /gene="uidA"
                     /locus_tag="TV191_000614"
     CDS             complement(8411..10201)
                     /gene="uidA"
                     /locus_tag="TV191_000614"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HEL1507151.1"
                     /translation="MLYPILTKTRKIYDLGGLWQFKLGDHNPQELLASDELMVVPTSF
                     NDVVVDKDKRNYIGDFWYERFVDVPDLAADEELVLRFGSVTHNATVYVNGQALGQHKG
                     GFTPFEVLVPETHYQDNQIKVSVCANNILDYTSLPVGNYSEETQEDGSIKKIVKENFD
                     FFNYAGIHRPVKLMVRPKCHISDITITSDLSEDMTSALVEVSVETSAAVDEVKVTIFD
                     EEHKLVAQAIDGKARLDKVRLWEVLDAYLYTAHVEIIVDGNVVDSYDEPFGIRSIAVE
                     KGQFLLNGKPVYFKGFGKHEDTFINGRGLNEAANLMDMNLLKELGANSFRTSHYPYSE
                     EMMRLADRMGILVIDEVPAVGLFQNFTASLDLSPKDNGTWSVMKTKEAHEQAIRELVK
                     RDKNHPSVVMWVVANEPASHEEGAHEYFEPLIALYKALDPQQRPVTLVNLLLATPDRD
                     KVMDLVDVISLNRYYAWYVDHGDLIKGEVGLRQELLEWQKKFPNKPILMTEYGADTLP
                     GLHSMWDIPYTEEFQCRFYEMSHRVFDEIPNLVGEQVWNFADFETNLMIFRIQGNHKG
                     LFSRNRQPKHVVGLFKERWNTIPHYNYKKK"
     gene            complement(10222..11250)
                     /locus_tag="TV191_000615"
     CDS             complement(10222..11250)
                     /locus_tag="TV191_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEL1507152.1"
                     /translation="MKKVVSLGEILLRLSPPQYQTLKQATSLDCQFGGSELNVISSLA
                     QLGHQVSLISAIPDNDLGQMTKTFLFSRQINQEHIIEKGQRLGLYYYQKGFSLRASRV
                     TYDRCHSAFWESKRADYDLEHVFDEADWFHVSGITPALTSDLYELTYYLMTKARAEGL
                     TISFDLNFRASLWSSFQEARDLLSPLVQLADVCIGIEPLTLKGSGALDLKDQLGLNRP
                     YDDEALLKEVLARLADTYGVKCFAFTQREMDYTNEYLLKAYLYQNGSLYKTQKSGIQV
                     LDRVGTGDAFTAGLIHGLLSYKDEQATLDVAMASFKFKHTIEGDSNIMTQDDIDHLLA
                     KESHEIQR"
     gene            complement(11334..12878)
                     /locus_tag="TV191_000616"
     CDS             complement(11334..12878)
                     /locus_tag="TV191_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000416102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1507153.1"
                     /translation="MEKTIDQRVEEVTYNRAKVWQLVLFALNNASTNIYLFTFMFVTY
                     FSTGVLGLAAIFVSQIMGYIRIFDGFIDPAIGILIDKTETKFGKYRPILIIGNIITAL
                     SLILLLGLSGVSENIRFPLFILVLIIHKIGYSMQQTITKAGQTALTNDPKQRPIFNIV
                     DAIMTTLLMTGGQFVVSSFLVPKFGNFTPAFFHVLIYGTIVISAILGLLAVLGIWSKD
                     RKEFFGLGENTQKTALKDYLKVIKGNQPLQVLSIAAALVKFAVQFFGDSVVMVILFGV
                     LFGNYALSGQFSLLFIVPGILINIAFSGIARKRGLRFSYIRALQIGLVGLLAFGIVLF
                     MGNKGDLSLSHINLYTILFTVTLIIARYASQAPASLVLTMGADISDYETSESGRYVSG
                     MIGTIFSLTDSIASSFAPMVIGAVLAGIGFSKTYPTIETPLTPSLKMALIALHVGIPF
                     VALLVALILMSFYKLDKEEMVRIQEKIQVMKASSDKERVQAIAKNVPLSDMDYVDVTK
                     YPVDKD"
     gene            complement(13293..14552)
                     /locus_tag="TV191_000617"
     CDS             complement(13293..14552)
                     /locus_tag="TV191_000617"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEL1507154.1"
                     /translation="MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADDVVTLDGV
                     PAISDVDSLIEIMKLMGAMVTYQGDTLEIDPRGVQDIPMPYGKINSLRASYYFYGSLL
                     GRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGAQISYEGASMHLMTEAQQLHGAHIYM
                     DTISVGATINTMIAATKAKGKTIIENAAREPEIIDVATLLNNMGAHIRGAGTDVITIE
                     GVERLHGTRHQVIPDRIEAGTYIALAAAVGSGVRITNVLYEHLESFIAKLEEMGVRMT
                     VEEDSIFVEKQEALKAVTIKTSPYPGFATDLQQPLTPLLLRTEGRGSIIDTIYEKRVN
                     HVPELARMGADIAILGSQIVYHGSNRLSGAQVKATDLRAGAALVIAGLMAQGKTEISN
                     IEFILRGYANIIDKLTALGADIQLIED"
     gene            complement(14868..16073)
                     /locus_tag="TV191_000618"
     CDS             complement(14868..16073)
                     /locus_tag="TV191_000618"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEL1507155.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TCVYTGSVHVFGEISTTAYVDINRVVRDTIAEIGYTEAEYGFSAESVGVHPSLVEQSP
                     DIAQGVNEALEAREGQSDDFNAIGAGDQGLMFGFAIDETPELMPLPISLSHQLVRRLA
                     TLRKSGEISYLRPDAKSQVTVEYDEHDKPVRVDTVVISTQHDPEVSNDQIRQDMIEQV
                     IKAVIPAHYLDEKTRFLINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYARHGGGAFSG
                     KDATKVDRSASYAARYIAKNLVAAGLASKAEVQLAYAIGVAQPVSVRVDTFGTSTVSE
                     SILEAAVRQVFDLRPAGIIKMLDLKRPIYRQTAAYGHMGRTDIDLPWEQLDKVSPLTE
                     AVAALSEGA"
     gene            complement(16406..18625)
                     /locus_tag="TV191_000619"
     CDS             complement(16406..18625)
                     /locus_tag="TV191_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL1507156.1"
                     /translation="MKSKKLMLMASLFMACHLTLTACQSTKQPTNQPKTKQTAKKATK
                     KKQSKKVKQTRKDRKGVAGIDFPTDDGFILTKDSKILSRTENGIVVEHNGHSHFIFYA
                     DLKGSKFEYLIPKDADLNKPEQTKAASGHHHTSANDPHHHYVFNPADIVAEDALGYIV
                     RHGDHYHYILKSSLGGQVAYPVPNHVPLSAPSSPSGKFAGVDYPTSDGFLFDGTGIVG
                     RTSYGLIVDHNGHNHLVTYESLRNSKWKHLIEQPKEEAPAKPQSDLEKTIALKKAYLA
                     KSLNIPEDSIRVEHTEEGIILDYPHGDHRHATYIDDIDLSKPFDPHAVDPHAKDRIGM
                     ATLRKLGFDEEVISSIIHANAPTEFPSRERDLEKMKAWLATVEYLNIGEIKDPLKRAG
                     LNLMPNIQILGIGFTPITDITPVYQFKNLKQLWMTQTGIKNYDFLKNLPTLEGIDISQ
                     NGVSDLSFLKAFPHYKVISAAGNDITDISILKELPNLESVNLDFNKITDLSALANAQK
                     LVAVSLEHNQIKDLSALSNKGQLTKLFVSNNPDLDLSTLKSSALKEITAKEVNLQSLS
                     FVKDLPALEQLVVDQNKLNSLTGLEHNKSLIQLSANQNMINSLALPGTQSSLQSLNLE
                     ENQLTNFEGVNNYLALEAINVNRNKINTLALKEPNQTLKYIQADGNHFPAEELAAESG
                     QFPQGIIKNFKAAEGGSLNNATPAEAVEDEHKPADTDQEAADKHDHEHHDHDEHHHG"
     gene            19152..20093
                     /locus_tag="TV191_000620"
     CDS             19152..20093
                     /locus_tag="TV191_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEL1507157.1"
                     /translation="MKTSEKIYQLLACSDDYVSGEYLAEQLKLSRTSVWKSIKSLESQ
                     GLHIESLKHKGYRLIQGDILLPELISQELNMPLSYHEKSQSTQLDAKQGIELKHTAPR
                     LYLAPSQYAAKGRLNRQFFASPHGGIYMSLHLKPNVPYADMPPYTMMVASSIVKAISR
                     LTGIDTQIKWVNDIYLGHKKIAGILTEAITSVETGVITDVIIGVGLNFFVTEFSENLK
                     ERAGSLFSNKPSITRNALIIDIWKLFTTIPIKDHIKVYKEKSLVLQKQVSFQENDRQK
                     TATAIDLTDEGHLIVQLDNGQLQVLRSGEISLSSWGD"
     gene            complement(20068..20271)
                     /locus_tag="TV191_000621"
     CDS             complement(20068..20271)
                     /locus_tag="TV191_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 family protein"
                     /protein_id="HEL1507158.1"
                     /translation="MTIRQFMFMAFICAFEAYFFSDLLFSGDYIFALFWGLLLFRDLR
                     RAYAIDQFTKNIINAVNPPRKKD"
     gene            complement(20652..22328)
                     /gene="dnaX"
                     /locus_tag="TV191_000622"
     CDS             complement(20652..22328)
                     /gene="dnaX"
                     /locus_tag="TV191_000622"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEL1507159.1"
                     /translation="MYQALYRKYRSQTFAEMVGQSVISTTLKQAVESEKISHAYLFSG
                     PRGTGKTSAAKIFAKAMNCPNQVKGEPCNHCDICRDITTGSLEDVIEIDAASNNGVDE
                     IRDIRDKSTYAPSRATYKVYIIDEVHMLSTGAFNALLKTLEEPSDNVVFILATTELHK
                     IPATILSRVQRFEFKAIKQPAICEHLAAILDKEGIAYEIEALHLIARRAEGGMRDALS
                     ILDQALSLSFDNRVTLAIAEEITGSISISALDDYVQHLIRQKTSQALANLETIYDSGK
                     SMSRFATDLLTYFRDLLIVKSGGDHHRQSALFDDNLAVSFDQLFTMIATVTKHLPEIK
                     KGTHPRIYAEMMTIQLAEQGQAADTAIPSSLLADVDDLKHEISQLRETISQLQAQKGL
                     TAQATPAHSIKPKAFTYKVDREKILKIMEETVQDSQQSRQYLEALKSAWNEILDSISA
                     QDRALLLGSEPVLANSENAILAFEAAFNAEQAMKRQDLNDMFGNIMSKAAGFSPHILA
                     VPKADFHHIRSEFAMTIKTKKETAKESEQATFDMPEGFDFLTDKIHLIED"
     gene            complement(22328..22825)
                     /locus_tag="TV191_000623"
     CDS             complement(22328..22825)
                     /locus_tag="TV191_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEL1507160.1"
                     /translation="MNKTTKIEHYQLLLAQAKALFSNESNALANLSNASALLKMTLPH
                     SVFAGFYLFDGQELILGPFQGKVSCVHIKLGKGVCGESAQSGQTIIVDDVKKHANYIS
                     CDSAAMSEIVVPMLKAGRLVGVLDLDSSLVADYDQIDQDYLEQFVALLLENTSFRFDM
                     FGVEN"
     gene            23005..23775
                     /locus_tag="TV191_000624"
     CDS             23005..23775
                     /locus_tag="TV191_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEL1507161.1"
                     /translation="MLLVFNGIEYECLNLVSPKQTFYQSAALILSTSLLGIYLIPFSL
                     AIAYLKRIYQIRISTLLLAGLGGLYISGFLASFGNQVLEQFWISLIKPNIALEEWTGA
                     LTGPFVEEPIKAFAAMLVIYLLPAINLKQKLVISLISGMGFQLTEDISYIASAADRSI
                     NDILPTTLARISSSPNSHWVYTGIFTMGAYLLIKKSQLFPRSLQIFWVVSPLALHFIW
                     NSPISDLAGVAVIHGTITTLIFISLFKKIHALDDSIAY"
     gene            complement(23957..24229)
                     /locus_tag="TV191_000625"
     CDS             complement(23957..24229)
                     /locus_tag="TV191_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002998338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEL1507162.1"
                     /translation="MLPSLILLFGWNAVVFAAYGSDKHRAQKGQWRLSEKMLLTLSLL
                     CGGIGAYLAGHYFNHKTKKWYFVLSWYMGILMTLVLCYYLYQWYIL"
     gene            complement(24252..24878)
                     /gene="udk"
                     /locus_tag="TV191_000626"
     CDS             complement(24252..24878)
                     /gene="udk"
                     /locus_tag="TV191_000626"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEL1507163.1"
                     /translation="MLKKPIIIGVTGGSGGGKTSVSRAILNSFPNARIAMIQHDSYYK
                     DQSHISFEERVKTNYDHPLAFDTDFMIQQLKELLAGRPVDIPIYDYKEHTRSNRTFRQ
                     EPQDVIIVEGILVLEDERLRELMDIKLFVDTDDDIRIIRRIQRDMVERGRSLESIIEQ
                     YTSVVKPMYHQFIEPSKRYADIVIPEGVSNVVAIDLINTKIASILGEL"
     gene            24974..26068
                     /locus_tag="TV191_000627"
     CDS             24974..26068
                     /locus_tag="TV191_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL1507164.1"
                     /translation="MITNLPTQWQEKLAKLGFTNLTPIQEQVFQPIVDGKSLLGISPT
                     GTGKTLAYLWPSLLRLSPKKAQQLLILAPNTELAGQLFEVTKEWAEPLGLTAQLFISG
                     SSQKRQIERLKKGPEIIIGTPGRIFELVRLKKIKMMAINTIILDEYDDLLSDSQYQFV
                     QKLSHYAPRDHQMIYMSATNKIEQASLADHTLVIDLSKQALPCIEHCYMLVDKRHRTD
                     ILRKLANIPDFRGLVFFNSLSDLGATEERLQYSGASVASLASDVNVKQRKAILEAFKE
                     QSISLLLATDIVARGIDIDQLEYVINAEVPRNKEQYTHRAGRTGRMGRSGIVITLVSH
                     PEDIKRLKKFTKVTEMYLKHQQLYQKEIRG"
     gene            complement(26333..27619)
                     /locus_tag="TV191_000628"
     CDS             complement(26333..27619)
                     /locus_tag="TV191_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEL1507165.1"
                     /translation="MKKLNYILIILLSLLLVGVAFTFIRSWKIGQDTQRVIKLEQTAS
                     KDSPKIKKVKYLKKGKQDWYYLSPIEKADDFYVSNLPMSLYQGKQTDKAVIMVKPKLE
                     ASHIKQVNQLVIYKTVYKPQLFGLKKTTEKAVSRYHVKEDYSPFKLEELVAGRLDRIE
                     EEVGKLYPGKEIKLSTDTMIEKNQVLSDGFAIDSGNLILFGHMSIPLASLFDVINPDF
                     LEGSDKTAYEEYLEEKKAKEAEKEGQKLVALTFDDGPDPVTTPQVLDILAKYQAKGTF
                     FMMGSKVVGHEALVKKVSAAGHDVENHSWDHPDLTTLTVDQIQTQINTTNQAIEKACG
                     KRPVYLRPPYGATNDIVRRASGLKEMLWTVDTRDWENRNTAAIMANVKQQLQPGGVVL
                     MHDIHQTSVDALPSIMEYLKAEGYKCVTLSELYGSR"
BASE COUNT         8195 a         6647 c         5268 g         7807 t
ORIGIN      
        1 ttatctgttc aattgtttca cttatcaaca agcttatagc ttgtctatca tctgaagcaa
       61 ggttgagcat taggcacaaa aagaaaagct agaatgaccc tctagctttt ctttaggatt
      121 aacaggctct atcatctcca tatcggataa aactccccac cacagggatt atggggctat
      181 ttctgcagct acaaggggct gattaacagg ttttatcctg aaatcttttt aaatcattca
      241 gagcaatcac cgcagaacac gtaaagcctc tacttatcct gtagcaacct cagaagctat
      301 gccatagctg ggtatcaatc aagccacaaa aggcatcaac aggagacact ccagtgaatt
      361 cagattcacc agctaatttt gcaaccaaag ccttcatagt gttgtccttg ccatcgtagg
      421 cattaatata agtaccaacc tgtggcatat cagcaagggc aaaggcatgc tgaactgaaa
      481 caacgattgt tgggacctca tggacgtaga atggctgatc cggtgttccc ttagcagctg
      541 gccagataat acgctgaact gtacctccag aattgacgtc caccaaatta agaattaaat
      601 cataatgctc tgtaatgttt gaaatcggct gcttttgtgc ataaacatta gcaatagccg
      661 ctgcacgctc ttcctctggt agctgcatga ttcgctcttc ggttgattcc cagacagtta
      721 cctcatgccc acgcgcctct agcaattcct tgacaatgtc tgaggcccgt ttcttctgtc
      781 ctgcaatcat agcaccaaag ccacccttat agccctccac gttaacaatc agcacacgct
      841 tgtagcgctc tggagttacc gggaaaatcc ctgcctgctt gtttttcaca agggtaatgg
      901 ccttgtcggc aacctcatct gcaattgctt gagcctctgg tgtgttaatc aagaccatcg
      961 ccttgtcctt aggcagcata atatcttctc ggtgtccttc aaagcgatga agtccaagct
     1021 ttgctttcaa gccaagcgta cgacgaaggg cgtcatgaag gcgttcgtca cttaaaattc
     1081 ctgcctcata gccctctttc atccattgta ggtcttcatc tgggtcatta aagaataaaa
     1141 agagatcgca gcctgcctca atcgctgttg gtaacaataa gcgacgtggc attgaggctg
     1201 tcatcgcaac catatgcgaa gcgtcagtca caatagcacc attatagcca agctcaccac
     1261 gcagcagctc atctaagagg gttttattaa gtgaggctgg aagcatatca tctagctcac
     1321 gctcagggtg catggccttt tcaacatttg gcaggtgaat atgtcctgcc ataataccag
     1381 gtaagccagc ctctgcaagc tcgccataaa tacgtccaaa gctagatagc cactcctcct
     1441 tggtcattgg gtttgaggca aaggacaaat gatggtcacg ctcatcaata ccatcaccag
     1501 ggaagtgctt ggcaaagggc atgataccat attccataat ccccttcata tactctttgg
     1561 aaagctcaat gatttgatca acatttaccc cccagttgcg attagcaatg attggattac
     1621 gccaattacg cgtcaaatca acaattggcg caaaggaggc attacagcca acagctgacg
     1681 cttccagtcc tgcaatccgt cccatttcat aagcgtattt aggatcgttt gtcgcagcta
     1741 ccttgatttc atcaccaacc ttagtgccat cattgacagc accatcacca ccagcctctg
     1801 tattggcagc aatgagcatt ggaatcttgg atttggtttg taaaatataa ttttgatccc
     1861 aaatttctga agccatgcct ttattgtagc gaacagctgc aatatgataa tcctcaagca
     1921 cctgagttaa ataatcctct gatcgactag cccccatatt aacaaatagc tgacctatct
     1981 tctcctccaa ggtcattgct gcaatggtat cctccaccca gcaaatagct tcttcgtcta
     2041 ggctatatgg tttttttctt aaatctacta aatgtgtcat tgtacttcct ttcaactaaa
     2101 gccttctctg cttgcttttc tgttttaatg aatggcgcta cagcaacctg ctaccaagcc
     2161 ctaacaggct cagctccact ggtcagctac ctgcctacct atcaagatta cgccagaagg
     2221 cttctgtaag gctcttgaca tcaagctctg tcaagtcacc agttgtaaaa gcttcagcag
     2281 catgtgacag atcctgccac gagctagcct ccttaccaac gaggattgga aaaaaagtga
     2341 tctggttttg ctcagcagct gctagatcac ctggtgaatc tcctatcatc atcatgcgct
     2401 ctctcacata tccttcatca atgagctgtg ctatgacagc ctcttttttg ccacgatcct
     2461 gacaatacaa gccatcaaca tgtgtcatca ggccttgatc ctgccattcc ttttgaacgg
     2521 cctctttatt agctgagctg acaacaaaaa cctggccaag ctggtgcaag gccttaagag
     2581 cagctaaagc tcctagaaat gccaatgcct ctcctttgta ggcctcaatc tgacggttta
     2641 cctcatttga ccagtccaag gccttttgca ggtcatcact aggacgctta agaagctccg
     2701 cctccagaga ctgattggat aatgaggcag tgtgttgtac ccattgcttt aaagcgtcaa
     2761 tccctgtaac tcctgcgtat tctagcccca taacaagccc aacaaagcgg ttaacaccgc
     2821 gtgtacgcga ataaagatta atgcgatccc actcttttaa gaaagacgct tggtctgcta
     2881 ccgcaaaata atccgccgca agcggaccaa aaaagagctg atgcttataa gtcatggtgt
     2941 ccattgcgca gccatctgag tccacacaaa agacaaattg ttcagtttta gctgtcattc
     3001 caacctccaa atcatctgat gaattaattc taacacagta agaaaacgct gtcaatcata
     3061 aatcctaatc aagcagcgtt tcatttttaa aagctatcat tacttgttga ttgctaaaaa
     3121 aggctagagt gataaggaac aatagaagcc acaaatcatc atacctttat taatggcagc
     3181 ttggctacaa agcaagctgt cacgatagaa aaaccacttg aggcattgca gtttgagttc
     3241 tcaagtggtt tattttttag cttagacgcc tgaataagct gcaaatccgc catcaattgg
     3301 cagaacaacg ccgttcacaa aggaagcaga ctgctcatca gccaagaaaa agaggcctcc
     3361 aattaattct tctgcctcac caaagcgtcc cattggtgta ttcttaagga ttttttcagc
     3421 acgagccgtt ggctgtccgt cctctgtgaa aaggaggcta cggttttgat tggttaccaa
     3481 aaatccagga gcaatggcat tacaacgaat gccaacctta gaaaaatgaa cagccaacca
     3541 ctgggtaaag ttggaaatgg ctgccttagc cccagaatag gctgggatct ttgttaatgg
     3601 cgtaaaggca ttcattgaag aaatgttaat aatatttgcc cccttacgac caaccatatc
     3661 ctgagcaaag acttgcgtcg gcaacaaggt gcctaaatag tttaaattaa agacaaagct
     3721 gatacctgct tcatcaaggt caaagaaggt ttttgtatcc tctggcaggc ttgtgtcgtg
     3781 aaactcatta tcggttgttg ccttagggct gtttccgcca gcgccattca ctaaaatatc
     3841 tgctggacca aaatctgcta aaactgcctg acgaacggcc tctaggtttt ctttagacaa
     3901 tacatttgcc tgataggcct ttgcaatacc accctctgcc tcaatatcat caacaaaggc
     3961 ctgtgccgcc tcttggttaa ggtctaacag tgccacctta gcccctgctt ttgcaaatgc
     4021 ctttgccata ctgccacaaa ggacaccgcc agctcctgtg atcacaacaa ccttgtcctt
     4081 aaattcaata actcgactca tctcatgccc ctttttctat ttatctccaa ctgtttttac
     4141 agtaatgcca aaatctggta tctttccagc tgcacgcata ttagcctcat aaagcccatt
     4201 aaaataggtc gcaccaagtg cccggtcata cagcccatag ccaggggttt tggtttgatc
     4261 tccccagata cgacgaccat gatctggacg aagtggtcct tgccagtcat aatcaaccaa
     4321 taatttgata atagcattca tatcaatgtc accagcctgt gacaagtgag cggtttcttg
     4381 gaagccccaa tcaccagcag tgacattacg cgtatgcata aagttaatac gctggcgctt
     4441 aagcgcgtac tccgtcatag cgatcacatc attttgagga tcagaagcat aggagcccac
     4501 acacatggta atcccattat taggggaatc ataaaggtct aagaagcgct ctacagcctt
     4561 ttgacctgtt atgatacgtg gtaagccaaa aataccataa ggaggatcat cagggtggat
     4621 agccatctta acgccagctg cctctgctgt tggcataata gccttaataa aataatctaa
     4681 attagcccac aggtcttctt cggaaatatg atgacgataa tgctcaataa tagccttcat
     4741 ctcttctttt gagtaagaaa aatcccaacc cggtaggttc aaatcatctg ccacaggatc
     4801 cacatctgcc aagtctgcct ttaaaaaagc aagtgaggtt gatccatcag gcaatgggta
     4861 attaagatct gagcgagtcc aatcaaacac tggcataaaa ttatagcaaa ccacaggaat
     4921 acctgcctta ccaacattga tgatagaggt cttataattt tcaatcagct catcacgatt
     4981 gggctttcct tgcttgatgt cctcgtgaac aggaattgat tcgatgactg aaatctcaag
     5041 gcctgcagcc tcaactatcc tcttcaattc aaggatattt tctagtggcc aagcctgacc
     5101 aactggtaca tcatacacag ctgttacaat tccctgcata ccaggaatgg ccttgatttc
     5161 ctctaaactt actggatcat gctttccata ccagcgaaac gacattttca tagtatcata
     5221 cctcgagttc tcgtaaactc cttttccttt cgattcacac aattgttatt tattattgtt
     5281 tttggggcta atacccttgc aactaaaggg cctgggcctg ctacttggtc tagcctttgt
     5341 aatctagtca atcaacaaga cgccgacagc agctagcagg ccgatattgt cctagcctct
     5401 tttaagacta ggaccttaat catagagcaa catcatattt ctatgcttct tctagttaac
     5461 gaccaaggca gcctagttaa aatactggat agcattattg taggcaatgt cctgagccat
     5521 tttaccaagt gcctgataat cctctggtac ctcaccttct tcaatccact caccaaggta
     5581 ggtcgacaaa atacgtctga aataatcatg acgctgatag gataaaaatg aacgtgaatc
     5641 cgttagcatg ccgacaaaat tagctaacaa accttgctca gccaaggcat tcatctggct
     5701 aatcatacca agcttggtat cagcaaacca ccagcctgca ccgaattgca gatagcccgc
     5761 aataccgttt tcattggctt ggaaattagc tagtgtatta gcaaccgcga tattatagct
     5821 cggatttagg ttataccaaa tcatctttgg caggctgtct ctttgcacca gatgatccag
     5881 caggcgattc atattgattg ctagtcctgt ttggtctccc agtgagtcaa cacccacatc
     5941 tgcccccagc ttgttgaata tagctgaatg attattgcga agagcaccaa aatgcacctg
     6001 agtaacaaag ccatagtgct tataaagcct gcaaagctct gcaaacaccg ctgtctgcca
     6061 ttgcttgacc tctaacggct gcggctgata gccctctaaa acccttgtca tgagacggtc
     6121 taattgctct ggctctgctg cttcaaagac aatctctgta aagctgatgt cactggcctt
     6181 acaaccattt tctgcaaaat aggcaatacg ctcttccata gccgctataa agctcttaaa
     6241 atctgtaata gttcttccgg tagcttgagc aagacgagcc acaaaatctg caaagcgctg
     6301 atgctcaata aaagcctcat ctggtctaaa ggttggcgcg acaaccgtct caaaggtatc
     6361 atcagcagct aacctcttat gccaagctag gtcatcaagc gggtgatctg tcgtaccaat
     6421 aaaccgcact cggctatctg caatcaactt tctaggacta atctggtgct caaccaagta
     6481 agcattgata cgatgataga tttcctctgc attatcctca gtcagtagct cacagacacc
     6541 aaagacattt ttcaactcca tcactgacca gtggtaaaca ggattgccat aggagcgctg
     6601 aagtgtacgg gcaaaggcct tgaatttatc cagcttagag gctgagcctg tgatttcttc
     6661 ttccgaaatg ccattagcgc gcatcaagcg ccacttgtaa tgatcaccac caagccaaag
     6721 gtcaacaata ttgtcataaa ccttgtcctc aaaaatttcc tttggatcta agtgacaatg
     6781 gtaatcaaaa ataggctgat ccttgatttg ttgatagagg cgctttgctg cctcattttt
     6841 tagcataaaa ttgtcgtcat taaaagccat ctcgtcctcc tcttatgacc aattccctta
     6901 atcaagggct gatacaaatg acgctgcaat acgggttaca ctatcatagc cctcagcctc
     6961 aactcggcta gctaaggctg aaccaatccc aacagcaaca gcacctgcat ttttccactc
     7021 cttgacattg tcaatcgaca caccacctga tggcatcaaa tcaacctcag gaataggacc
     7081 atgaatatcc ttaataaagc ctggtcctac aacacctcca ggaaagacct taataatcgg
     7141 acaagaggca ttcattgctg tgacaatttc agtagctgtt gcacagcctg ggaaataaag
     7201 atttgatgcc tgattggcaa cctctgctat ttctctagaa aaatgaggac taactaaaaa
     7261 gctagcacct gctgcaatag cttctcttgc cagatcaggc gtcatcactg tcccagctcc
     7321 aataatcaca gcatcatcat gctcaaactc agctgacaat attctaataa cctctgaagc
     7381 atttggagta gaataggtaa tctcgatatt acgaataccg cctaaaatag catgcttagc
     7441 aatggcaata gcgtcttcta ctgtttttcc acgaataata gcaaaaaaat aattctcttt
     7501 taatcggttt agcataggct cctccttttc atgaaaccgt tgtcttagtt ttattatata
     7561 aatcatcaga tgatttgtca aggaaaaagc aaaaaaagga cttggttcta gtatctctaa
     7621 aaccaagccc tcttattcga gccaagaagc aaatcactca aaactcaata gactgtttcc
     7681 ggcaagcaag cttaagctta tgatagaaaa gccgttcgct taactgtcat gatgtgcagg
     7741 agcatagcgt catgtgccgc gatcggatct cccgctttaa tcgcattcag aatatctctg
     7801 tgggcttgta gagaatcttc tttcatctga cgatttgtgt aattggcatt gatcagatga
     7861 atcgactgat tgatcaccgg tagcaagcta tccatagcaa tattgccact gtattttgcc
     7921 atcaaggaat ggaaattcac atccagctgc aaatgcttag gatcaccagc agctacggcc
     7981 tcttcaatat caacaacaag cttctctaag gcttcaacct cctttggcgt tgcatgctgt
     8041 gctgtcaaag cggcaatcct aggctcaagc aatagccgca attcaaacaa atcagcggtc
     8101 agcttggctg tgtccttgac taaggaaaag cctaaaggat cctcagaaac accttttttc
     8161 gagctaatat aagtacctga tccttgtcta acctctaaaa catttctagt tgctaagctt
     8221 ctaacagctt ctctaatagt gcttcttcca acctctaagt cctgtgctaa ctcatattca
     8281 ttggggagct ttgctccaac ctcataccca cgttctaaaa ttagctttaa caagcgctct
     8341 gctgtttttt cgactaaagg cctagccata caatcccttc ttcctactta ttgctagcta
     8401 ctattgtaca ctatttcttt ttataattgt agtggggaat ggtattccag cgctctttaa
     8461 acaaaccaac aacatgctta ggctggcgat ttctagaaaa aagcccctta tgattgcctt
     8521 gaatacggaa gatcatcaga ttagtttcaa aatcagcaaa attccatacc tgctctccaa
     8581 ctagattagg aatctcatca aaaacgcggt gactcatctc atagaagcgg cactgaaatt
     8641 cctctgtata tggaatatcc cacatcgaat gaagaccagg aagcgtatct gcaccgtact
     8701 ctgtcatcag gataggcttg ttaggaaact tcttctgcca ttctaatagc tcctgacgca
     8761 gcccaacctc tcctttgatc aagtctccat gatcaacata ccaagcataa taacggttta
     8821 aggagatcac atcaaccaga tccatcacct tatctcgatc aggtgttgct aatagcagat
     8881 taaccaatgt tactggacgc tgctgcggat ctagtgcctt ataaagagca atcagcggct
     8941 caaagtattc gtgtgctccc tcttcatggc tggcaggctc attggccacg acccacatga
     9001 caacagaagg gtgatttttg tcacgcttga cgagctcacg aattgcttgc tcatgcgctt
     9061 ccttagtttt catgacagac caagtgccat tgtcctttgg cgaaagatcc aaggaggctg
     9121 taaagttttg gaagagccct actgccggaa cctcatcaat aaccaagatt cccatacgat
     9181 ctgccagacg catcatctcc tcagagtaag ggtagtgtga ggtacgaaat gaattggcac
     9241 caagctcctt gagcagattc atatccatta aattagctgc ttcattcaat ccacgaccgt
     9301 tgataaaggt atcctcatgc ttaccaaagc ccttgaaata aacaggcttg ccatttagta
     9361 aaaattgtcc tttttcaact gcaatacttc tgataccaaa tggctcatca taactatcta
     9421 caacattgcc atctacgatg atctcaacgt gggcagtgta tagataagca tctaaaactt
     9481 cccataaacg aaccttatca agtcttgcct tgccatcaat agcctgcgca acgagcttgt
     9541 gctcttcatc aaagatcgtc accttaacct catcaacagc tgctgaggtt tcaacagata
     9601 cctcgactaa ggctgatgtc atatcctcag acaagtcact cgtgatcgtg atatctgaga
     9661 tatggcattt tggccgcacc ataagcttca ctggacggtg aataccagca tagttgaaga
     9721 agtcaaaatt ctccttgaca atttttttga tactgccatc ctcttgagtt tcttcactat
     9781 aattgcccac tggaaggctg gtataatcta aaatattatt ggcacaaaca gataccttaa
     9841 tttgattatc ctgataatgg gtctcaggca ccaacacctc aaatggagtg aagcctccct
     9901 tgtgttgccc taaagcttgc ccattaacat agactgttgc attgtgcgtg acagagccaa
     9961 agcgaagtac cagctcctca tcagcagcaa gatctggcac atcaacaaag cgctcgtacc
    10021 aaaaatcacc gatgtaattg cgcttgtcct tatccacaac cacatcatta aaggaggtcg
    10081 gcacaaccat cagctcatca gaggctagga gctcctgcgg gttatggtct cctagcttaa
    10141 attgccagag cccccctaaa tcataaatct ttcttgtttt tgtcagtatt gggtataaca
    10201 tacgatttct cctttatcac attatcgttg aatctcatgc gattccttgg ccagtaaatg
    10261 atcaatgtca tcttgtgtca tgatattact atcaccctca atggtatgct taaacttaaa
    10321 gctagccatt gcaacatcta aagtagcctg ctcgtcttta taacttaata agccatgaat
    10381 cagccctgcc gtaaaagcat cgcccgtccc tactcggtcc agaacctgaa taccagattt
    10441 ttgggtttta taaaggctgc cattttgata caggtaggcc tttaacaggt attcattggt
    10501 atagtccatc tctctctggg taaaggcaaa gcattttacc ccataggtat cagctaacct
    10561 agccagcacc tccttcaaca aggcttcatc atcatagggt ctattcaagc ctaattgatc
    10621 ctttaaatca agcgcgccgc ttcccttaag cgtcagcggc tcaatgccaa tacaaacatc
    10681 agccagctga acaagaggcg acaagagatc tctagcctcc tgaaaggagg accatagact
    10741 agccctaaaa ttcaaatcaa aggaaatagt caatccctct gccctagcct ttgtcatcaa
    10801 ataataggtc agctcataaa gatcactcgt tagagcaggc gttatcccag acacatgaaa
    10861 ccaatcagcc tcatcaaaaa catgctccaa atcatagtca gcacgctttg actcccaaaa
    10921 ggctgaatga cagcggtcat aggtaacccg acttgctcgc aaagaaaagc ccttttgata
    10981 ataataaagc cctaaacgct gacccttttc gataatatgc tcctgattaa tttgacgcga
    11041 aaagagaaag gtttttgtca tttgtcccag atcattgtct ggaatagctg aaataagaga
    11101 gacctgatgc cctagctgag caaggcttga gatgacatta agctcagaac ctccaaattg
    11161 acaatctagg cttgttgcct gctttaacgt ctggtattga gggggtgaca atcgcaagag
    11221 gatttcaccc aaggatacaa cttttttcac aacattcctc cttatactat caagctactc
    11281 tattatttta taaaaaagtc agccactcct caaagaaata gctgacccag cacctaatcc
    11341 ttatcaacag gatattttgt cacatcaaca tagtccatgt ctgacagtgg tacattttta
    11401 gcgatagcct gcacgcgttc cttatcagag cttgctttca tcacttgaat cttctcttga
    11461 atacgcacca tttcctcttt gtcaagcttg tagaatgaca tcaaaatcaa agccactagt
    11521 aaggctacaa atggaatacc gacatgcagc gcaatcaagg ccatctttag acttggggta
    11581 agcggtgtct caatcgttgg gtaagtcttt gaaaaaccaa taccagccag cactgcacca
    11641 ataaccattg gcgcaaatga tgatgcaatc gagtcagtca aggagaagat tgtaccaatc
    11701 attcctgaga cataacggcc tgattctgat gtttcgtagt ctgaaatatc agctcccatt
    11761 gttagcacca agctagcagg cgcttgtgag gcatagcgag caataatcag tgtcacagta
    11821 aacaaaatag tgtaaaggtt aatatgactt aggctgagat cccctttatt acccataaag
    11881 agcacaatac caaaggctaa caagccaacc aagccaatct gaagagctct gatatatgag
    11941 aaacgcaaac ctctcttacg agcaatacct gaaaaagcaa tattaatcaa aatccccgga
    12001 acaataaaca gcaatgagaa ttgaccagac aaagcatagt taccaaataa aacaccaaac
    12061 aagataacca tgacaaccga atcaccaaag aattgaacag caaacttaac caaggctgcg
    12121 gcaattgata ggacctgtag cggctggttg cccttgataa ccttcaaata gtccttcaga
    12181 gctgtctttt gcgtattttc accaagacca aagaattcct ttctgtcctt gctccaaata
    12241 ccaagcactg ccaatagacc caaaatagct gagataacaa tcgtgccata aatcaacacg
    12301 tggaagaagg ctggtgtgaa gttaccaaat tttggaacca agaagcttga cacaacaaac
    12361 tgtccaccag tcatcagcaa ggttgtcata atggcatcaa caatgttaaa gattggacgc
    12421 tgcttcggat cattagtaag ggctgtctga ccagccttag tgatggtttg ctgcatagag
    12481 tagccgatct tatggataat caaaaccaga ataaaaagtg gaaaacgaat gttctcacta
    12541 actccactta gaccaagcag cagaataagt gatagggctg tgataatatt tccgatgatt
    12601 aggatcggac gatacttacc aaacttagtt tctgttttat caatcaagat accaatcgca
    12661 ggatcaataa agccatcaaa aatacgaata taacccatga tctggctgac aaaaatagct
    12721 gccaagccta gaacacctgt tgaaaagtag gtcacaaaca taaatgtgaa taggtagata
    12781 ttggttgaag cattgtttaa agcaaataaa acaagctgcc aaaccttagc gcggttatag
    12841 gtaacctctt caaccctttg gtcaattgtt ttctccatca gagaaatccc ccttttatca
    12901 ttcgcttatt gtgtaagcgt tttatttcta catgcttatc ttactattca tctgatgatt
    12961 tgtcaacaca atttaaactt ttttcgccta attttaaaaa ataaagctta tttaggattt
    13021 taatcattaa attcatctga taatttctgg tgtctttaaa aataatcatc agacaattac
    13081 tcattgacat caaaaaaact gagccctgtg caatacagaa ctaaatcctt tcactaatat
    13141 gtcgtgtcca acttttgggg gtcagtacac aggatagaca gggggttctt aaaaatcaaa
    13201 agcccctaaa accactctca taccaagcag tcttaggagc tctaagcatt catgtcaggt
    13261 gataatcatt aggctatgaa agccttcagt tcttaatcct caataagctg aatatcagcc
    13321 cctaaggctg ttagcttatc aataatgtta gcatagccac gtaaaataaa ctcaatattg
    13381 ctaatctcgg ttttaccctg agccattaga cctgcaatca ccaaagcagc accagcccgc
    13441 aaatcagttg ccttaacctg tgccccactg aggcgattag agccatgata aacaatttgg
    13501 ctgccaagaa tggcaatatc tgctcccata cgagcaagct ctggcacatg gttgacacgc
    13561 ttttcatata tcgtatcaat gatactacca cgaccctcag tccttaaaag cagaggagtc
    13621 aaaggctgct gtaggtcagt ggcaaagcct ggatagggag aggttttaat agtgactgct
    13681 ttcaaggctt cctgcttttc cacaaaaata gaatcctctt caaccgtcat tctcacaccc
    13741 atttcctcta gcttagcaat aaagctctct aagtgctcgt aaaggacatt ggtaatcctt
    13801 accccactac caacagcggc tgccaaggca atataggtac cagcctcaat gcgatctggg
    13861 atcacctgat gtctggtgcc atgaagcctt tcaactccct caatcgtaat cacatcagta
    13921 cctgcaccac gaatatgcgc ccccatgtta tttaacagtg tcgcaacgtc aataatctca
    13981 ggctctctag ctgcattttc aataatggtc ttaccctttg cctttgtcgc agcaatcata
    14041 gtattaatgg tagcgcctac actgatagta tccatgtaga tatgagcgcc atgaagctgc
    14101 tgagcctctg tcatcaggtg catgcttgct ccctcataag atatctgggc ccccattgct
    14161 tcaaaagcct tcagatgaag atcaataggc ctagggccta agtcacagcc acccggcaag
    14221 cccacaaccg cctgcccaaa gcgtcccaat agactgccat aaaaatagta agaggctctt
    14281 aggctgttaa ttttaccata aggcatagga atatcttgaa cccctctggg gtcaatctcc
    14341 aaggtatccc cctgataggt caccatagct cccatgagct tcatgatttc aataagactg
    14401 tcaacatcac taatagctgg taccccatct aaagtgacaa catcgtctgc caaaataatc
    14461 gcaggaatga gagctacaac gctattttta gcgcctgaaa ctgccacctc tccggataag
    14521 gcttttccac cattaataat aatttttcgc atactttcaa aactttctga tactagaatt
    14581 caaccttttt attttatcac aaatagcggt ctattacaat cacctcatca ccagctgctg
    14641 caacaggctt aacaacctgc ctcttgatca cttttcataa caggtttttg agaagccaga
    14701 ctcttatctg gatctttctt ctgctgcgca ggcctttttg tctttcatag ccgccaagcc
    14761 tgacaagttt tgctggacta aaaaagctcc caaccagcag cacagccgct agctcaggag
    14821 ctattatacc tttaagtcaa tcatcaacta accggcgctc aatctgctta agcaccctct
    14881 gacagtgctg ccaccgcttc tgtcaatgga gataccttgt ccaattgttc ccaaggcagg
    14941 tcaatgtctg ttcgccccat gtgcccatag gctgctgtct gcctatagat tggacgcttg
    15001 agatcaagca tcttaatgat ccctgctggg cgcaggtcaa agacctgacg aacagccgct
    15061 tccaaaatac tttctgacac tgttgatgtc ccaaaggtat ccacacgaac tgaaactggc
    15121 tgtgcaaccc cgatagcata ggctaattga acctctgctt tacttgcaag ccctgctgcc
    15181 acaaggtttt tggcaatata acgagctgca taagaggctg agcggtcaac cttagttgcg
    15241 tctttaccag agaaggcacc accaccatga cgcgcatagc caccataggt gtcaacaatg
    15301 atcttacgac cagtcaagcc agaatctccc tgaggaccac caataacaaa acgcccagtc
    15361 ggattgataa ggaatcttgt cttctcatct agataatggg ctggaataac agccttaatc
    15421 acctgctcaa tcatatcttg acgaatctgg tcattgctta cttctggatc atgctgggtt
    15481 gatataacaa ctgtatcaac acgaacaggc ttatcatgtt catcatattc gaccgtaacc
    15541 tgtgatttag cgtctggacg caaatagctg atctcacctg attttcgcag tgtcgccaaa
    15601 cggcgtacaa gctggtgaga taaggaaatc ggcagtggca ttagttctgg tgtctcatca
    15661 attgcaaagc caaacattag cccctgatcc ccagcaccaa tcgcattgaa atcatcgctt
    15721 tgtccttcac gtgcttcaag tgcttcatta acgccttgag caatatctgg tgactgctca
    15781 accagagatg gatgaacacc cactgattct gctgaaaagc catattctgc ctcagtatag
    15841 ccaatctcag cgatggtatc acgaaccaca cgattaatat ccacataggc agttgttgaa
    15901 atttctccaa aaacgtggac cgagcctgtg taaacgcagg tctctgcagc aacgtgtgcc
    15961 tctggatcct tggctaaaat agcatctaaa atagcatctg aaatttggtc tgcaatctta
    16021 tctggatgcc cttcagatac tgattcagac gtgaaaagtt tacgttctga cataaaaatg
    16081 tcccccctta aaaagaatga tacccaccag cacacatgcc agataggatt ttcctagcct
    16141 cactcatcaa gccagccgcc aatacaaaag gactgtatcc aagctagcct atgactaacg
    16201 cttagcgagt tacaaagtac cggcttttag actgctatcc tcagataaca aagccgtctt
    16261 atcgggactt aataacttat ttattatacc acttttagcg ggatttgtaa gagctccatc
    16321 agcttttttc tcaaaataag aaaaggaata ccgctacagg cgtattcctc ctcttaatgt
    16381 cgtgataatc agcgcaagct atcgattaac catggtggtg ctcatcgtga tcatgatgct
    16441 catggtcatg cttatctgct gcctcttgat cagtatcagc cggcttatgc tcgtcttcaa
    16501 cagcttctgc tggtgtggca ttatttagac taccaccctc tgctgccttg aagttcttga
    16561 taattccttg tgggaattgt ccgctttcag cagctagctc ctcagctggg aagtggttac
    16621 catcagcctg aatgtatttc agggtttggt taggctcctt caaggccaag gtgttaatct
    16681 tgttacgatt aacattaatt gcttctaggg cgagataatt gttgacaccc tcaaaattag
    16741 tcagctggtt ctcttcaagg ttaagagact gtaatgagct ttgtgtacct ggtaaggcca
    16801 agctattaat catgttctgg ttagctgata gctgaatcag gctcttattg tgctcaagac
    16861 ctgtcaagct gttaagcttg ttttggtcaa ccactagctg ctctaatgcc ggtagatcct
    16921 tgacaaagct aaggctttgt aaattaacct ccttggcagt gatttccttg agagcagagg
    16981 attttaaggt tgacaaatca aggtcagggt tgtttgacac aaagagtttg gtcaattgtc
    17041 ccttgtttga caaggcactc aagtccttaa tctgattgtg ctctaggctg acagcgacta
    17101 gcttttgagc atttgccaag gcagaaagat ctgtaatctt gttaaagtca aggttaacgg
    17161 actctaggtt tggcaattct ttcaaaatag aaatatctgt gatatcattt cctgctgccg
    17221 aaattacctt gtaatgcgga aaggctttaa ggaagctcaa atcagaaaca ccattttgag
    17281 aaatatcaat tccttcaagc gttggcaggt tcttcaagaa atcataattt ttaatgccgg
    17341 tctgtgtcat ccacaattgt ttgaggttct tgaactggta gactggggta atatcagtga
    17401 ttggggtaaa gccaatacct aaaatctgta tattaggcat caggtttaaa cctgcccgct
    17461 taagaggatc cttaatctca ccgatattga ggtattcaac agtcgccaac catgccttca
    17521 ttttctctag gtctcgctct cttgatggaa actcagttgg tgcatttgca tggataatgg
    17581 acgaaatcac ttcctcatca aagccaagct ttctcagagt tgccataccg attctatcct
    17641 tagcatgcgg atctactgca tgaggatcaa aaggttttga taaatcaata tcgtcaatat
    17701 aggttgcatg acgatggtca ccatgtggat agtcaagaat gataccttct tctgtatgct
    17761 ccacacgaat gctgtcctca ggaatattta atgacttagc caaatatgct tttttcaaag
    17821 caatcgtttt ctcaagatca ctttgtggct tagctggtgc ttcttccttt ggctgttcga
    17881 ttaaatgctt ccacttgctg ttacgcaagc tttcataagt gactaaatga ttgtggccat
    17941 tgtgatcaac aatcaatcca tatgatgttc gaccgacaat acctgtcccg tcaaacaaga
    18001 agccatcact tgttgggtaa tcaacacctg caaattttcc agacggtgat gatggagctg
    18061 atagtggcac atggttaggc actggataag ctacctgacc acctagtgag ctttttagga
    18121 tatagtggta atgatcacca tgacggacaa tatagcccaa ggcgtcctca gctacaatat
    18181 cagctgggtt aaacacatag tgatggtgcg ggtcattagc actagtatgg tgatgacctg
    18241 atgctgcctt ggtctgctca ggcttgttta ggtcagcgtc ctttggaatc aggtactcaa
    18301 acttgctgcc cttgagatct gcataaaaaa taaaatgcga atgcccatta tgctcaacaa
    18361 caataccgtt ttctgttcta gataagattt ttgaatcctt ggtcaagata aaaccgtcat
    18421 cagttggaaa gtcaatcccc gctactccct tacggtcttt tcttgtttgc ttaacctttt
    18481 tagactgttt ctttttggtc gcttttttag ctgtctgttt tgtcttaggc tgatttgttg
    18541 gctgctttgt cgactgacaa gctgtcaggg tcaggtgaca agccataaac aggctagcca
    18601 ttagcattaa ttttttactt ttcatctttc ctccataaat taactggtta aataagatat
    18661 taactagtta aatataccaa aaaaacaaat aatttcaact gttttcttat ttttaattca
    18721 ttctcattca acaatcatag tagcttggct aggttggcag aaaaatgagc ctctcctact
    18781 ctcatcaaat aaacagatag ccttaatgat ggctgagata acagcataca aagtcgttaa
    18841 agtcacttgt aagaaaaaga aggacatatc ttaccaccac tatcttgctc atcaaagccc
    18901 tacggctttc agacaaaatc ttcataacag cggaaaggct gatgaagcag ctcagacaaa
    18961 aagagcaagc tccttaacgt caaggatcag agatcagcac aaaaataaca gcaggctaca
    19021 ttaagaactg caattccttg aaatagaatt gcttttttac aaaaaaatcg tctccctaga
    19081 ctgttccatc atctcacgtc atttgtatta tttgctcttg aaatccagtc attttatact
    19141 atactagaat tatgaagaca tctgaaaaaa tttaccaatt actagcttgc agcgacgact
    19201 atgtcagtgg agaatacttg gcagagcagc tcaagctttc tagaacctct gtctggaaat
    19261 ccatcaaaag ccttgaaagt caaggccttc acattgaatc cctcaagcat aagggctatc
    19321 gccttattca aggagatata ttgctgccag agctcatcag ccaagagctc aacatgcctt
    19381 tatcttatca tgagaaaagc cagtcaacac agctagacgc caagcaagga atcgagctaa
    19441 agcatactgc tcctaggctc tatctcgctc caagtcagta tgcggccaag gggcggctta
    19501 atcgccaatt ctttgcgtca cctcatggcg gcatttacat gtccttgcat ctcaagccaa
    19561 atgttcctta cgcagacatg cctccttaca ccatgatggt ggcctctagt attgttaagg
    19621 ctatttcaag attgaccggt attgacaccc aaatcaaatg ggtcaatgat atttaccttg
    19681 gccataaaaa aatcgccggt atcctgactg aggccattac ctctgtggaa acaggcgtca
    19741 ttactgatgt gattattggc gtagggctta acttttttgt aaccgaattt tctgaaaacc
    19801 tcaaagaacg agcaggctct ctttttagca acaagcctag tattactcga aatgccctaa
    19861 tcattgacat ttggaagctc tttaccacaa taccaatcaa ggaccatatt aaggtctaca
    19921 aagaaaaatc acttgtcctt caaaaacaag tgagcttcca agaaaatgat cgtcaaaaaa
    19981 cagcaactgc cattgacctg actgatgaag gacacctcat cgttcaatta gacaatggtc
    20041 agctacaggt cttaaggagc ggcgaaatta gtctttcttc ctggggggat taacagcatt
    20101 aatgatgttt ttggtaaatt ggtcaatagc ataagcacgc cttaaatctc taaagagcaa
    20161 aagaccccaa aacagagcaa aaatataatc gcctgaaaat aataaatcgc tgaaaaaata
    20221 agcttcaaag gcacaaatga atgccataaa cataaattgt cgaatagtca tactactatt
    20281 ataccaagaa aactaaattt ccactaacga ttttcacgca gcttgaagaa aaaggcagtt
    20341 agcctgcttc aagctttttt gctgctcttt gatagcctgt aacagtcaaa taaaaaagag
    20401 ctcactctaa aaacgacgcc aaaagccagc ttgattgcta ggcttgtagt caattgtctc
    20461 aaatcagtga atcactaagc cttataagaa ctcagtcatt gggtcacaat gacacctagc
    20521 tctaagcagc aaaaaagaga accacaccgg tcctctctag cttggcttgt cagctatcta
    20581 ttagtgctga caatgagccc tgtcatctcc ttattctaga caattgatac actaccaatc
    20641 atcagctagc gctaatcctc tatgagatga atcttatcag ttaaaaagtc aaacccctca
    20701 ggcatgtcaa aggtcgcttg ctcagactct ttggctgtct cttttttggt tttgatggtc
    20761 atggcaaact ccgagcgaat atggtggaag tctgcctttg gtactgccaa gatatgagga
    20821 gaaaaccctg ctgccttact catgatattc ccaaacatat cattcaaatc ctgacgcttc
    20881 atggcctgct cagcgttaaa ggcggcctca aaggccaaaa tagcattttc actattggct
    20941 aaaacaggct ccgagcctag taacaaagct cgatcctgtg cagaaatact atctaaaatc
    21001 tcattccaag cactttttag cgcttctaaa tattgtcgtg actgctggct atcttgaaca
    21061 gtttcctcca tgattttcaa tatcttttcc cgatcaacct tgtaggtaaa ggcctttggc
    21121 ttgatggaat gagctggtgt agcctgcgca gttagaccct tttgagcctg tagctgtgat
    21181 atcgtctccc tcagctgact aatctcatgc ttcaagtcat caacatcagc tagcaggcta
    21241 gacggtatcg cagtgtctgc tgcttgtcct tgctctgcca gctgaatggt catcatttca
    21301 gcgtagattc taggatgggt tccttttttg atctcaggca aatgcttggt tactgtagca
    21361 atcattgtaa aaagctgatc aaaagacact gcaaggttat catcaaaaag agctgactgc
    21421 ctgtgatgat caccacctga tttcacaatg agcaggtctc taaaataggt tagcagatcc
    21481 gttgcaaagc gactcatgct cttgccacta tcataaattg tttctagatt agctaaggcc
    21541 tgacttgttt tttgcctgat gagatgctga acgtagtcgt ctaaggccga aatagaaata
    21601 gagcctgtga tttcttctgc aatagcaagc gtcactcgat tgtcaaagga taggctcaag
    21661 gcctgatcta aaatggatag ggcatcacgc atgccacctt ctgctcgtct tgcaattaaa
    21721 tgaagcgcct ctatttcata ggctatgccc tccttgtcca gtatcgccgc caaatgctca
    21781 caaatagctg gctgcttaat ggctttaaat tcaaatcgct ggactctaga caaaatagta
    21841 gctggaatct tgtgtagttc tgttgtggct aggataaaaa ccacattgtc actcggctct
    21901 tcaagggtct ttaggagcgc attgaaggcc cctgttgata gcatatgcac ctcatcaata
    21961 atataaacct tgtaggttgc ccggctagga gcataggttg acttatctcg aatatcgcga
    22021 atttcatcaa caccattatt agaggcagca tcaatttcaa tcacgtcctc caggctgcca
    22081 gttgtaatat ctcggcaaat atcacaatga ttgcagggct ctcccttgac ctgattaggg
    22141 cagttcattg ccttagcaaa aattttggct gcgctggttt taccagttcc tcttggacct
    22201 gaaaagaggt aagcatggct tatcttttct gactcaacag cctgctttaa ggtggtcgaa
    22261 ataactgact gcccaaccat ttcagcaaag gtctggctac gatacttccg gtaaagggct
    22321 tgatacatta attctcaact ccaaacatgt caaaacgaaa agatgtattt tctagtaata
    22381 aggctacaaa ttgctctaaa tagtcttgat ctatctgatc ataatcagca acaagactgg
    22441 aatccaaatc cagaacacca acaagcctgc cagccttaag cattggcaca acaatctcgc
    22501 tcatggctgc tgaatcacag gaaatgtaat tagcatgctt tttgacatca tcaacgatga
    22561 tggtttgacc agattgagct gattctccac atactccctt gccaagcttg atatgcacac
    22621 aggaaacctt tccctgaaag ggaccaagga tcaattcttg accatcaaaa aggtaaaagc
    22681 ctgcaaaaac agaatgaggc agggtcattt ttaagagggc actagcatta gagagattgg
    22741 ccaaggcatt gctttcatta gaaaataagg ctttagcttg agccaataat agctgataat
    22801 gttcaatttt tgtcgtctta ttcatggttc ttattataac atatctgcta ctaatcgtta
    22861 aacgatttcc acaggaaaag aattttaatc agcctctcta gaaaagaaag agattttatg
    22921 ataaaatagt gagtaatatt aaaaaaatag gagagtcaga tgccgttgtt gagatataaa
    22981 aagattatcg ctacgacctt atttatgtta ttagtgttta atggtattga gtatgaatgt
    23041 ctaaaccttg tcagtcccaa acaaaccttt taccaatccg ctgccttaat cctctcaacc
    23101 agcctactag ggatctatct gattcccttt tcactggcta ttgcttatct caagcgcatc
    23161 taccagataa ggatctcaac cctgctatta gctgggctag gcggtcttta tattagtggc
    23221 tttttagcct cctttggcaa tcaggtttta gagcaatttt ggattagcct gataaagccc
    23281 aatattgcct tagaggagtg gacgggagct ttgacagggc cttttgtgga agagcctatt
    23341 aaggcctttg cagctatgct tgtcatttat ttgctgccag ctattaatct taagcaaaaa
    23401 ttagtcatca gtctcatttc tggcatggga ttccagctga ctgaggacat tagctatatt
    23461 gcaagtgcgg ctgatcggtc cataaatgac attttgccta caacgcttgc caggattagc
    23521 agctcaccaa actctcattg ggtctatact ggtattttta caatgggagc atacctttta
    23581 attaaaaaat ctcaattatt cccaaggtct ctgcagattt tctgggtggt aagtcctcta
    23641 gccctacatt ttatatggaa ctctcctatc tcagatttag ctggtgtcgc agttattcat
    23701 ggaacaataa caacccttat ctttatcagt ctattcaaaa aaatccatgc cctagacgac
    23761 agcatcgcct actagcgtca taggacacga gcaaccaagc ccagccgcat ttgggcatgt
    23821 gatggctcat atgcatatat agctactcac ctctcgctta agctataggc agctaaatac
    23881 ctatcacaat agcagaaaaa atgactacca gtcttaaaag ggctagtagt cattttaagc
    23941 taaaaacaag cacttcttac aggatatacc actgatacag ataatagcaa agcacaaggg
    24001 tcatcagtat ccccatatac catgaaagga caaaatacca tttcttcgtt ttatggttaa
    24061 aataatgccc agctagatag gctccaatcc caccacataa gagtgacaac gttaatagca
    24121 ttttctcaga aagtcgccat tgaccttttt gggctctgtg tttatcactg ccataggccg
    24181 caaagaccac agcattccaa ccaaaaagca agattaggct tggtagcatt tgtctgtctc
    24241 caatcacagc actacagctc acctaagatg ctggcaatct ttgtgttgat gagatcaata
    24301 gcaaccacat tgctaacccc ttctggaatg acaatatcag catagcgctt acttggctca
    24361 ataaattgat gatacatcgg cttgacaacg cttgtgtact gctcaataat gctctcaagg
    24421 cttctgccac gctcaaccat atcacgctga atacgacgga taatccgaat gtcatcatct
    24481 gtatcaacaa aaagcttgat atccatcagc tcacgcaaac gctcgtcctc taataccaga
    24541 atcccctcaa caataatgac gtcctgaggc tcttggcgaa aagttctgtt gctgcgagta
    24601 tgctccttat aatcatagat tggaatatca acaggccggc cagccaagag ttcctttagc
    24661 tgctgaatca tgaaatccgt atcaaaggct aacgggtgat cataattagt cttaaccctt
    24721 tcctcaaagc tgatatgtga ttgatccttg taatacgaat catgctgaat catcgcaatt
    24781 ctcgcatttg gaaagctatt taaaatggca cgagacacgc tagtcttacc accaccagaa
    24841 ccaccagtca caccaataat aatgggtttt ttaagcattg taaactccaa atctaaaagt
    24901 ctttcggtct attttaccaa atttgccact ataatgctat aatgaagaga aaacaaaata
    24961 aaaggataga tatatgataa ccaaccttcc cactcaatgg caggaaaagc tggcaaagct
    25021 tggctttact aatctcaccc caatccaaga gcaggtcttt cagcccattg ttgatggcaa
    25081 aagcctatta ggcattagcc ccaccggaac aggcaaaact ctggcctatt tatggccaag
    25141 ccttctcagg ctaagcccta aaaaagccca gcagttgctg attttagcac ctaatactga
    25201 gctagctgga cagctttttg aggttaccaa ggaatgggca gagcccttag gattaactgc
    25261 gcagctcttt atttccggaa gcagccaaaa acgccagatc gaacgcctca aaaaaggccc
    25321 agaaatcatt atcggaacac cgggacgcat ttttgaatta gtaaggctta aaaaaatcaa
    25381 aatgatggcc atcaatacca tcattttaga tgaatacgac gacctactga gtgactccca
    25441 ataccagttt gtccaaaaac tctcccatta cgcgcctcgt gaccatcaaa tgatctacat
    25501 gagtgctact aacaagatag agcaagccag tctagcggat cataccttgg tcattgatct
    25561 gtctaagcaa gcattgcctt gcattgagca ctgctacatg ctggttgaca aaaggcatcg
    25621 gaccgatatc ctacgtaagc tagcaaatat tcctgacttt cgtggtctgg tcttttttaa
    25681 cagcctgtca gacctaggtg ctactgaaga acgcctgcaa tatagtggag cttctgttgc
    25741 ttctctagcc agtgatgtga atgtcaagca gcgaaaggcc attttagaag cctttaaaga
    25801 gcagagcatt tcactgctgc ttgcgacgga catagtcgct cgtgggattg atattgacca
    25861 gctagaatac gtcattaacg ctgaggttcc ccgtaataaa gagcaatata ctcatagagc
    25921 tgggcgaacc ggtcgtatgg gacgatcagg gattgtcata actcttgtca gtcaccctga
    25981 agacatcaag cgccttaaaa aatttaccaa ggtcactgag atgtacttga agcatcagca
    26041 attataccaa aaagaaataa gaggctagct caaaggatat aaacctaaaa agcttgcctc
    26101 caagtatgat gtaaagcaac taatcactat ttcttaccct tgctactaaa aaaacgaacg
    26161 taaagtcctt ctgacatgaa gtcaaaacct tacgttcgtt ttatattata ctgacaccac
    26221 tggctttatt agtatagtag atactggcca tgcttagcca gactagatac tttcttgaag
    26281 tgagcccgcc atttagtcat gctctagagc cttacttgct ttttctgact gactagcggc
    26341 taccatatag ctcagataag gtcacacatt tgtatccttc cgcttttagg tattccataa
    26401 tacttggcaa ggcatctaca ctggtctggt gaatatcgtg cattagaaca acccctccag
    26461 gctgcaattg ctgcttgaca tttgccatga tagcagcagt attacgattt tcccaatctc
    26521 tggtatcaac tgtccaaagc atttccttaa gacccgatgc ccttctaaca atatcattag
    26581 tagctccata aggaggacga agatagactg ggcgttttcc acaggccttt tcgatggctt
    26641 gattggtcgt attgatctgt gtttggatct gatcaacggt tagggtcgtc aaatcagggt
    26701 gatcccaaga atgattctca acatcatgac cagcagcact aaccttctta accaaagcct
    26761 catggccaac aaccttagac cccatcataa aaaaggtccc cttggcctga tatttggcca
    26821 aaatatctaa aacctgcggt gtggtcacag ggtctggacc atcatcaaag gtcagagcga
    26881 ctagcttttg tccctctttt tctgcctctt ttgccttctt ttcctccaaa tactcttcat
    26941 aagcagtctt gtctgaaccc tctagaaaat ctggattaat cacatcaaac aggcttgcaa
    27001 gaggtattga catatgacca aataaaataa gattacccga atcaatggca aagccatcgc
    27061 ttaatacctg atttttttct atcatcgtat cagtgctcag cttgatctct ttgcctggat
    27121 aaagcttgcc aacctcttcc tcgatgcgat ctaagcgacc agcaactagc tcctctagct
    27181 taaaggggct ataatcctct ttcacatggt aacgactaac agccttttct gtagtctttt
    27241 ttagaccaaa taactgaggc ttgtagaccg tcttgtagat aaccaattga ttgacctgct
    27301 tgatatgtga agcctcaagc ttaggcttta ccatgataac agccttgtca gtctgcttgc
    27361 cttgatacag agacataggc agatttgaca cataaaaatc gtcagccttc tcaatcggag
    27421 acaggtaata ccaatcctgc tttcctttct tgagatactt gacctttttg atctttggac
    27481 tatccttaga agcagtctgt tcgagcttaa tgactctctg agtatcctgc cctattttcc
    27541 aagatctaat gaaggtaaac gcaacaccga ccaacaataa acttaataaa ataatgagaa
    27601 tataatttag ctttttcaat ctcgtcctcc aattacccta caattttaac acaagatagt
    27661 tggaaaataa ataaaaaaag ttaggtttcc ttaacttttt tcagtccaaa ataagggcaa
    27721 aaaagtgttt tatggtgcag gatttgcctg agttattttc cctttatcac agccatttgt
    27781 cactggataa ggggctagat attataccta aagcttctct ttattgctat cattattctg
    27841 acattcttag gcatgctatt tcccttgata ggacttgatt gctgtttctt tagcttgtaa
    27901 ggatctccta aaaatga
//
LOCUS       DARYXW010000018        27147 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.018, whole genome shotgun sequence.
ACCESSION   DARYXW010000018 DARYXW010000000
VERSION     DARYXW010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27147)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27147)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27147
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.018"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(<1..600)
                     /locus_tag="TV191_000629"
     CDS             complement(<1..600)
                     /locus_tag="TV191_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1507166.1"
                     /translation="MKRQSNIRRLCHQALAATLITGSLIGTGLLGNKVVYGDMSADVK
                     KIEQVLQSDSGKLKTVLGQISDPNTLFALFAIISADVNIDPESFSFILNGPITPLLSY
                     FNNPNKNDNRKAVVNEIKKRVSALEQAQKLETKAKIEKQIAESELEKTRNAFKVTIEN
                     LHKLEGLLDTEKQKTRKVEEDYQQAKTDKEKAEADKRNAE"
     gene            1005..1649
                     /locus_tag="TV191_000630"
     CDS             1005..1649
                     /locus_tag="TV191_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507167.1"
                     /translation="MPIAAYQYESVVEIISEINRLHYSFSSGLGALLCFNLKKSVSSV
                     VVNNRIDREFQELIVSYKARLNRNISQVSSIRHQFIGIRWRIKQAESISEKLLYYMSE
                     NHEFGRIPLNKCLNDFLGFRILVNNLEVVFAALQNDNRVTNIAKLYLRTDGDYKGIHL
                     YFKNGNNRFFPWELQIWDPEQSRLNELSHKEHKQKRQYISLPQHYFDANLEKEE"
     gene            1654..2403
                     /locus_tag="TV191_000631"
     CDS             1654..2403
                     /locus_tag="TV191_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4065 domain-containing protein"
                     /protein_id="HEL1507168.1"
                     /translation="MYQHFILVASSYARGERVGFHLATEGQLDHVAIEEKMQRLSHIN
                     RDDVGVHSFVTDSADWQSVIELDSFFEDIMVCQDFDEFEQVLQSDSKISAIDVAKFFL
                     AMRPLSHLQLQKLVYLAYKTYLLAYGESLFDEKIVAFQYGPVVEEVYHSFKKYGSEVI
                     DIDDHTEYILKDIHLPQALGRMLLVEDAKKIVPVLLDVVKQYGDLTGGELVKLTHSEK
                     GPWQTVFRPQLNCEITDEVILAQGRYERLSS"
     gene            complement(2508..2657)
                     /gene="rpmG"
                     /locus_tag="TV191_000632"
     CDS             complement(2508..2657)
                     /gene="rpmG"
                     /locus_tag="TV191_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEL1507169.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(2673..2855)
                     /gene="rpmF"
                     /locus_tag="TV191_000633"
     CDS             complement(2673..2855)
                     /gene="rpmF"
                     /locus_tag="TV191_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEL1507170.1"
                     /translation="MAVPARHTSKAKKNKRRTHYKLTAPSVKFDETTGDYSRSHRVSL
                     KGYYKGHKIAKANAAE"
     gene            3125..3955
                     /locus_tag="TV191_000634"
     CDS             3125..3955
                     /locus_tag="TV191_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507171.1"
                     /translation="MFGKLLSLLGFVVALTGCGVSQAEKERVVTEYSPIIIKKFQTLG
                     YQGKITVDDYTKMIETGSERLYFTYSEEVDGKVISLKDSISIATYKSPEEDLADAEVD
                     MGIREEAMWQQPAVKAQAAQIKQLFSELETEDLKLISVTGQSVQTISDSDGELIREDV
                     VRGRNELSQDASNNREAGLSIGGYYHIDVSKYLKNHVLEIRIDFDWRMSEEEQDDLSG
                     PRLDFSDRIKSLDFTCLWDGYYKVGFDRVSRSNRSGDIQDMIVLDIRGGKLVRSFSVL
                     "
     gene            4015..5295
                     /locus_tag="TV191_000635"
     CDS             4015..5295
                     /locus_tag="TV191_000635"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEL1507172.1"
                     /translation="MKLQKPKGTQDILPVAAAKWQYVEGVARETFKQYHYGEIRTPMF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PVKLYYIGSMFRYERPQAGRLREFHQIGVECFGSANPATDVETIAMAYHLFERLGIKE
                     VTLHLNSLGNAASRAAYRQALIDYLSPMRETLSKDSQRRLDENPLRVLDSKEKEDKIA
                     VANAPSILDYLDEESQAHFDAVRSMLEVLAIPYVIDTNMVRGLDYYNHTIFEFITEVD
                     QSELTICAGGRYDGLVEYFGGPATPGFGFGLGLERLLLILDKQGVELPVEEGLDVYIA
                     VLGAYANVAALALTQAIRRQGFTVERDYLGRKIKAQFKSADAFKAKVVITLGESEIKT
                     GQAVLKHNQTRQEMTVSFDQIQTNFASIFAECIQ"
     gene            complement(5500..6792)
                     /locus_tag="TV191_000636"
     CDS             complement(5500..6792)
                     /locus_tag="TV191_000636"
                     /inference="COORDINATES: protein motif:HMM:NF025854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEL1507173.1"
                     /translation="MAINAIFHLYTSVVNIVIVNYFFRQKNGQLATFKNIGYLSFLVF
                     IECCTHFFVSGSYASLITLTCSLVTSLIISSSYRYSMKQCIFWSVTLQSIGILLEASL
                     GIILISLKYQISSISGTFLFINLLTISSIIIIFVLKQLFLKTTDNWLDEQTQTNWILK
                     LSIIPMISLSLLLLQLLRLKEEPLFDLFTILLTLGFIIITITSLYLYTYISDQHLQMQ
                     DINLDRVRFQSELKHLENVKENQLSIRALKHDLHNQNIVLLGLLEQKQYTKAQQLLNH
                     NLNLLDGTDTFFTNDTILNYLLNQKAVVAKKNGIVLDIHCLIPTNISLKTEVISVIIG
                     NLLDNSIAATIRNQNKAEKQIQLKVRLFKNQLHIDIENFFDPKELASRSQRKKDGLGI
                     KNVQKIVQQYYGLYQQTIDNNIYKVSIIFSNIVLVSQQ"
     gene            complement(6782..7498)
                     /locus_tag="TV191_000637"
     CDS             complement(6782..7498)
                     /locus_tag="TV191_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1507174.1"
                     /translation="MLKIALCDDNKAFATAVEDLLYQYNQLVPVELDIYEDPCQLIQS
                     LSNDYHIFLLDIEMDNMSGIALAEHIRKDNLSAIIIFLTSHKEYMENIFHVQTFDYLI
                     KPLNEPYFFECLNRALRVLELDKKFFTFSSCHSYYSLSLNDIIYFEKEGRKVLIHTKD
                     KTYSTFLSTKALLKELPEQFIQTHHSYVFNVNYFYKFENNDITLAIDNTRFFIIPISR
                     KFKKGIQENIFSKLRRVNGY"
     gene            7752..7976
                     /locus_tag="TV191_000638"
     CDS             7752..7976
                     /locus_tag="TV191_000638"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507175.1"
                     /translation="MNYSRPCIKDIYPIYKLSDTMFRIGAQINITTEFNDSNYETGAS
                     FTHKLWPHFKECPACGHGNSNDWEIFSHYG"
     gene            7987..8907
                     /locus_tag="TV191_000639"
     CDS             7987..8907
                     /locus_tag="TV191_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1507176.1"
                     /translation="MEQYELMVRSLSKRYARDGSYANRDLHCVFKSSEITALIGHNGA
                     GKTTLLNQIIGNIKPDVGDISFLDCSFVKSPKIARKNTSMMPQLHAPLKGITIKQAIS
                     SIGKIRGLSGKLLETEVQELIQELGLIKWQNTVGEKLSGGLKRLTSFAMAVIAAPKIV
                     LLDEPTNDVDPIRRIKLWLYLKKMAAKGHIVIVVTHNILEVEKYADAYYLLEKGEVKS
                     SGAVKTLSSNPKSRISILFRDQKALEEYPFAYSLGGDDNEAITIMDNKEMTALLNWLG
                     IHLSSDTIVQYSITTLGLNDYYEELSDEED"
     gene            8894..9634
                     /locus_tag="TV191_000640"
     CDS             8894..9634
                     /locus_tag="TV191_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1507177.1"
                     /translation="MKKISVTYQFLSLLNWSFIRHKSLILLCSVIQFFMTIALVYGYS
                     LIIADDTVQTVYYLASGSVTIGMITIGCTVSAQSISSDKRDGIVSYIQTLPVLRSLIL
                     LSDLLIWTLTALIGVGVSIAVVYLKFQILPQLSLATFLILPLVLMTMISMGFAIAYWS
                     TPSTMMLVTQLLLMIGLLFSPIMYPAERIPEVILRGYHFLPFIPAGDLIRETVYLGHS
                     ISVVKLVVLLLWLVATALLSVNWLNRQS"
     gene            9791..11539
                     /gene="aspS"
                     /locus_tag="TV191_000641"
     CDS             9791..11539
                     /gene="aspS"
                     /locus_tag="TV191_000641"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEL1507178.1"
                     /translation="MKRSMYAGHVRKEHIGRTIVLKGWVSRRRDLGGLIFIDLRDREG
                     VMQLVINPEDVSGDVMATAERLRSEYVIEVEGSVEARQQANDKLATGAVELKVSGLTI
                     LNTAKTTPFEIKDGVEVSDDTRLRYRYLDLRRPEMLESFKLRAKTTHVIRNYLDNLGF
                     IDVETPMLTKSTPEGARDYLVPSRISQGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLSEQEIQDIVEGMIAKVMKDTKGIEVKLPFPRMAY
                     DDAMNHYGSDKPDTRFDMLLQDLTDLVKEIDFKVFSEAQAVKAIVVKGHADRYSRKDI
                     DKLTEFAKQFGAKGLAWLKVVDGAFTGPIAKFLTGVKSKLTESLQLEHNDLVLFVADT
                     LEVANNTLGALRTRIAKELDMIDMSQFNFLWVVDWPMFEWSEEEERYMSAHHPFTLPT
                     AESAHELEGDLAKVRAVAYDIVLNGYELGGGSLRINQKDMQERMFRALGFTAEEANEQ
                     FGFLLEAMEYGFPPHGGLAIGLDRLVMLLAGKDNIREVIAFPKNNKASDPMTQAPSLV
                     SEKQLEELQLQIEHHD"
     gene            11532..12479
                     /locus_tag="TV191_000642"
     CDS             11532..12479
                     /locus_tag="TV191_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL1507179.1"
                     /translation="MIKKTTYRKRVKYLINRGAKKIGLLHAVKSISKEKYTEKISASL
                     LYGILSSIAVNFFFQPGHVYSSGATGLAQVISAISHHLWGFEIPVALAFYVTNIPLLV
                     LAWYKIGHKFTIFTFITVSMSSFFIQIMPQVTLTTDPLINAIFGGLVMGLGIGTGFKS
                     RISSGGTDIISLTLRKKTGKDVGNLSLMINGVIMAFAGLLFGWQYALYSMVTIFVSSR
                     VTDAIFTKQKKMQATIVTSCPDKVIHMIHKKLHRGVTSINDAEGTYKHEHKAVLITIL
                     TREEYSEFKWLMLKTDPNAFVSVAENVRIIGRFVESDED"
     gene            12495..13376
                     /locus_tag="TV191_000643"
     CDS             12495..13376
                     /locus_tag="TV191_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL1507180.1"
                     /translation="MPANKSLKLKNCCFIILGSAIYAFAFVYFYMANRIAANGLAGLT
                     QVANALFQINPSITGYLINLPLVLLGARLFGRRAMVYTVTGILSLYWFVWLFQQLPLF
                     IDLDHDNLVVSLLAGILGGLGGGIVFRNGGTIGGSDIIAKLIEDRFGLQLNQALLGID
                     IFVIVVSLTYISIPQMMYALIASFMYSRIVHLVQNGGYSARGTFIISDYSQTISQFIM
                     EELGRGVTYLHGEGAYSGREKQVIYVALGRSDVRELKAFIAQVDPNAFVSFFDVNEVN
                     SPEFIATKSKYHKTKKR"
     gene            13520..14434
                     /locus_tag="TV191_000644"
     CDS             13520..14434
                     /locus_tag="TV191_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL1507181.1"
                     /translation="MTNLDKWHRVRELLLIAVGVAIYTFGFVNFNMANELAEGGVAGI
                     TLILHAHFGINPAYSSLLFNLPLFMLGAKIFGRRSLALTIYGTVLMSVFIWLWQKVPM
                     ELGLENDMMLVAVVAGLFAGIGSGLVFRYGATTGGTDIIARIAEEKFGAKLGQTLLFV
                     DALVLTASLTYVDLKHMLYTLVASFVFSQMISVVQNGGYTIRGMIIITKQSQAAAQAI
                     LTEINRGVTYLKGQGAYSGHDYNIMYVTLNPTEVREVKRILAELDPDAFISIIDVDEV
                     ISSDFKIRRKNFDKPIEKALQKKSNMLK"
     gene            14606..16000
                     /locus_tag="TV191_000645"
     CDS             14606..16000
                     /locus_tag="TV191_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEL1507182.1"
                     /translation="MEALSIQHYALDTAEKNLLTIDSLTLNQGERVFIIGDNGAGKTS
                     FLKTIIGESTNYSGFLQVHGDIAYVPQIKSTSPQSGGERAMSYLKEAFQARPSLLILD
                     EPSSYLDHANRDWLINQLKRYRGTLLVVSHDRYLINQLSQKIWLLEHQTIKTYHGNYD
                     DYQRSRQLEEDKQLRAFLEYQRKTNQLKKSLTRKKVQANKMAVKKKSVSRSDWKTNSF
                     AGSYDSQAKAMAKAAKAMENRLTRMKEVNSPRKKAWAKLKKDPNEGALPNTLLHLQEG
                     TLTRDHQLLFDYPGIVIRSHSRIAIIGRNKAGKSSFLDQLAAQALSGFYAQNLRITYF
                     KQDQADLEPDQTAVELISRQSSQDRVTILNYLAMMGIDYDKANQKVAVLSGGERVRLA
                     LVAALLTDHQLLILDEPTIYLDLVAIEALESCLIDYPAALLLVSHDLAFVNKVATEIY
                     EVKDHHLTAYHFED"
     gene            complement(16048..17739)
                     /locus_tag="TV191_000646"
     CDS             complement(16048..17739)
                     /locus_tag="TV191_000646"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEL1507183.1"
                     /translation="MDTKTLIAAEIAKIVPELEQAAIFNLLETPKNSDMGDLAFPAFS
                     LAKALRKAPQAIASDLAERIDASQFEKVAAVGPYVNFFLDKASISAQVLTQVIADGAD
                     YAQQDEGQGRHIAIDMSSPNIAKPFSIGHLRSTVIGDSLAHIFAKMGYKPVKINHLGD
                     WGKQFGMLIVAYKKWGNEAAVQAHPIDELLKLYVRINAEAETDPSLDEEAREWFRRLE
                     ERDQEATELWQWFRDESLIEFNRLYDQLGVSFDSYNGEAFYNDKMDEVLELLEDKGLL
                     VESKGAKVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKRTYDFAKSVYVVGNE
                     QAAHFKQLKAVLKEMGYDWSDDMTHVAFGLVTKGGAKLSTRKGNVILLEPTVAEAISR
                     AANQIEAKNPKLANKEAVAHAVGVGAIKFYDLKTDRMNGYDFDLEAMVSFEGETGPYV
                     QYAHARIQSILRKASFTPATDTSYSLNDPESWEIIKLIQDFPRIIKRAFDNFEPSIMA
                     KFAIHLAQSFNKYYAHTRILEDDPERDNRLALCYATAIVLKEALRLLGVEAPNEM"
     gene            18016..18453
                     /gene="argR"
                     /locus_tag="TV191_000647"
     CDS             18016..18453
                     /gene="argR"
                     /locus_tag="TV191_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEL1507184.1"
                     /translation="MNKIERQQQIKQLIQAEHIGTQEEIRRLLQKDGIVVTQATLSRD
                     LREIGLLKLRDDRGKLYYSLSEPVATPFSPDVRFYVLKVDRAGFMLVLHTNLGEADVL
                     ANLIDNDAIEDVLGTIAGADTLLVICRDEEIAKRFEKDLAAGL"
     gene            18455..18805
                     /locus_tag="TV191_000648"
     CDS             18455..18805
                     /locus_tag="TV191_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HEL1507185.1"
                     /translation="MPYRESLHQLIAALEKHSSIIAYKEAQQHLLQRTDYNQKAYQMK
                     RHQQDTYLFRQIAKDKAAEESAFKAQQLREDLDHQPLIDDYRDKMQNASDLVRYITGT
                     IEDELNKEFNDGKG"
     gene            18792..21347
                     /gene="mutS"
                     /locus_tag="TV191_000649"
     CDS             18792..21347
                     /gene="mutS"
                     /locus_tag="TV191_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEL1507186.1"
                     /translation="MAKANVSPGMQQYLDIKKDYPDAFLLFRMGDFYELFYEDAVKAA
                     QILEIGLTSRNKNADNPIPMAGVPYHSVQQYIDVLIDLGHKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTAVDSSRPDSPNNFLVAVDFDGKAYGLSYMDVSTGEFFATDLADFAS
                     VKSEIQNLKAKEVLLGFELSEEEQAILVKQLNLLLSFEMTALEDSPLIDHQLTAVELS
                     AAGKLLHYVHQTQLRELSHLQALVHYDIKDYLQMSYATKSSLDLLENARTGKKHGSLY
                     WLLDETKTAMGMRLLRAWIDRPLVTSEAILERQEIIQVFLNAFIERTDLSDSLKGVYD
                     IERLSSRVSFGKANPKDLLQLGHTLAKVPYIKAILEAFNSPYLDKLVNQIDTLPELEH
                     LIRSAIDPDAPATINEGNIIRTGFDERLDHYRKVMREGTGWIADIETKERQASGISNL
                     KIDYNKKDGYYFHVTNSNLGMVPDHFFRKATLKNSERYGTAELAKIEGQMLEAREESS
                     SLEYDIFMRIRAQVETYIDRLQQLAKALATVDVLQSLAVVAEKNHYVRPLFNQESKIA
                     IDNGRHAVVEKVLGVQEYIPNSISFGPQTSIQLITGPNMSGKSTYMRQLALTVIMAQI
                     GSFVAAESASLPLFDAIFTRIGAVDDLISGQSTFMVEMMEANHAIKRATPHSLILFDE
                     LGRGTATYDGMALAQSIIEYIHDRVGAKTMFATHYHELTELSTKLTKLVNVHVATLEK
                     DGNVTFLHKIAEGPADKSYGIHVARIAGLPEDLLARADTVLTKLEAQSQARESVLSTT
                     EVRETQQLANQQLSLFTDDGSSSEIIKRLESVDVMNLTPIQAMTVLYELKKLL"
     gene            21494..23476
                     /gene="mutL"
                     /locus_tag="TV191_000650"
     CDS             21494..23476
                     /gene="mutL"
                     /locus_tag="TV191_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEL1507187.1"
                     /translation="MTTIIELPEVLANQIAAGEVIERPASVVKELVENAIDAKSSQIT
                     VEIEESGLKMIQITDNGEGMSHEDLPLSLRRHATSKIKSQSDLFRIRTLGFRGEALPS
                     VASISKLTIKTATADAEHGSILVASGGKIEQLEAVSTPVGTKIKVENLFYNTPARLKY
                     MKSLQAELAHVVDVVNRLSLAHPEIAFTLISDGKQLTQTSGAGDLRQALAGIYGLNTA
                     KKMIDISSADLDFEVGGFVSLPELTRANRNYITILINGRYIKNFLLNRAILDGYGSKL
                     MVGRFPIAVIDIQIDPYLADVNVHPTKQEIRISKERELMALISTAISESLREQDLIPD
                     ALENLARSSTRSFSKPEQTSLPLQPSQLYYDPQKNDFFTKETVVSEDSPQGFNHETLV
                     DSGVKQVDNLQLAKTESEAAAPSVKYASRPDPMLSDGEHPGLDVHNKQKLSQMLDRLE
                     NEEQSVFPELDYFGQMHGTYLFAQGRDGLFIIDQHAAQERVKYEYYRDKIGEVDNSLQ
                     QLLVPYLFEFSGSDFINLQEKMSLLNEVGIYLEPYGNHTFILREHPIWMKEAEIESGV
                     YEMCDMLLLTNEVSIKTYRAELAIMMSCKRSIKANHSLDDYSARQLLLQLAQCKNPYN
                     CPHGRPVLINFSKADMEKMFRRIQENHTSLRELGKY"
     gene            23487..24710
                     /locus_tag="TV191_000651"
     CDS             23487..24710
                     /locus_tag="TV191_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1507188.1"
                     /translation="MREFFQLPKQIQIRQFVRFITITLGSSIFPFMAMYYTSYFGAFW
                     TGILMMVTSFTGFIGTLYGGHLSDAIGRKKVIMLGSVASTLGWLLTILANVPKTVLPW
                     LTFVGILLVELASSFYAPAYEAMLIDLTDDSNRRFVYTINYWFINIAIMLGAGISGLF
                     YDRYFLELLIALLIINIVCFGIAYRYFGETRPEHYRFEHGIGILAGFANYRQVFKDRA
                     FVLFTIGTILFSSIWLQMDNYVPVHLKLYFEETDVLGIHLTSSKMLSLMVFTNTLLIV
                     LLMTVINRLTARWRLLPQLVIGSVIFAFGMLLSFTFTGFFAIWCSVVVFTIGEMLNVP
                     ANQVLRAEMMDQSKIGSYTGFVSMAQPLGAILAGLLVSLSHFTGQAGVQLAFVLIACV
                     GLYVIVLSAKMKKKV"
     gene            24712..25308
                     /gene="ruvA"
                     /locus_tag="TV191_000652"
     CDS             24712..25308
                     /gene="ruvA"
                     /locus_tag="TV191_000652"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEL1507189.1"
                     /translation="MYDYIKGQLTKITAKYIVVEANGLGYMITVANPYSFTDCVNQQV
                     TIYLHQVIREDAQLLFGFHSEEEKDVFLKLISVSGIGPTTALAIVAVDDNRGLVNAID
                     NSDITYLMRFPKIGKKTAQQMVLDLAGKFVEAPKEESSKPPKAKQQGNEQLDEAVEAL
                     LALGYKATELKKIRAFFEGTSETAEQYIKSALKMLMKG"
     gene            25318..25869
                     /locus_tag="TV191_000653"
     CDS             25318..25869
                     /locus_tag="TV191_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEL1507190.1"
                     /translation="MKRCAWVPQDNKLYCDYHDLEWGRPVYDDRALFELLCLESYQSG
                     LSWLTVLKKRPAFRSVFHHYDISAVASFSEQEMAAALQNAAIIRHKPKLIATVNNAAA
                     VQRIQQEYGSFSSYLWNFVGGQPIDRLVNDDNPAPAQTALSLKLSKDLKKRGFKWLGP
                     TTVYSFMQAAGLVNDHEENCEFR"
     gene            complement(26305..>27147)
                     /locus_tag="TV191_000654"
     CDS             complement(26305..>27147)
                     /locus_tag="TV191_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1507191.1"
                     /translation="RWDYGKIYQAIRKSKGLTQEKICGDFLARSTLARIESGQVIPKF
                     DTMIFLLNQLNMTLEEFRYVCNTYHPSTRQDILNQFYNQVSAVNITELEKLRQKCFNY
                     LKNKNDIPISYILDSVEVMISLRKKGVKNNQDLQELAYKIWNSLVKQDTWYEKDLQLL
                     HTILFHFPIEIIENISQKILDSLAKYKDYRNIKSSEYALLTNLSTIYLYHNLKKECEE
                     ITLLTIKLARQLKRYDSLGFSQVRLGICRNDDHLINKGLQLLQLTEETELLETLQHEL
                     KNYR"
BASE COUNT         7867 a         4737 c         5990 g         8553 t
ORIGIN      
        1 ttccgcattc cttttatcag cctctgcttt ttctttatcg gttttagctt gttggtaatc
       61 ttcctcaact tttcgagttt tttgtttttc agtgtctaat aatccctcta gtttatgtaa
      121 attttcaatt gttactttga aagcattcct agttttttct aattcacttt ctgcaatctg
      181 tttctctatt ttagctttag tttctaattt ttgagcttgc tccaaagctg agactctttt
      241 ttttatttca ttaacaactg cctttctatt atcatttttg tttggattgt tgaaatatga
      301 taataatggt gtgattgggc catttaatat aaaactaaaa ctttctggat ctatatttac
      361 atcggctgat ataatagcaa ataaagcaaa caatgtattg ggatcactaa tttgtcctaa
      421 tactgttttt aacttaccac tatctgattg taaaacttgc tcaatttttt ttacgtccgc
      481 actcatatct ccatacacaa ctttatttcc aagtagtcct gttcctatca ggcttcctgt
      541 gatgagagta gctgctaggg cttgatgaca caagcgtctg atgtttgatt gtcttttcat
      601 gatttagtcc tcacatatcg tcgaatgttt tttctaaaat tcttccaaaa aatcttaaca
      661 tgacgcttgc aggctgtgaa tacgttttgg gcaattcgcc tccgtagttt cgtttttttt
      721 aattcaatca ttaaacgtct gattttatca tgatataatt gatcttgttc aaggctgatc
      781 aggaaattct tgatgaagat gacagcttta tatcggtgtt tgggaaacca taagattggc
      841 aaggctacgc tgggcttagc tgacattgtt gcttcaaaat gctttcaggt gtagaaatgt
      901 tgacaagtat tctttaaaaa gatagactat agctagtagg atagaggtat gcacaggtga
      961 cagatgtgat acttgtgttt tttgctattt ttggaggttt ctgattgcct attgcagctt
     1021 atcaatatga aagtgttgtt gagattatta gtgaaatcaa tcgattacac tattcatttt
     1081 cttcgggttt aggagctctt ctatgcttta atttgaaaaa gagtgtcagt tcggtagtcg
     1141 ttaacaatcg tattgatagg gagttccaag agctcatcgt ttcttataaa gcaaggctaa
     1201 ataggaatat tagtcaagtc tcaagcatac gacatcagtt tataggcatt agatggagaa
     1261 taaagcaagc agaatctatt agtgagaagc ttttatacta catgagcgag aatcatgagt
     1321 ttggaaggat tcccttaaat aaatgtttga atgattttct tggatttagg atcttggtca
     1381 ataacttaga agttgttttt gctgctttgc aaaatgataa tcgagtgact aatattgcta
     1441 aattgtattt aagaacagat ggcgactata aaggtatcca tctatatttt aaaaatggaa
     1501 ataatcggtt ttttccatgg gaattacaga tttgggatcc agagcaatca cgcttaaatg
     1561 agctgtcaca taaagagcat aagcaaaaac gacaatatat atcactaccc caacattatt
     1621 ttgatgctaa tttagaaaag gaggaataac cgcatgtatc agcattttat tttagttgct
     1681 agttcatatg caagaggtga gagagttggc tttcacttag cgacagaagg tcaattggat
     1741 catgttgcca ttgaagaaaa aatgcagcgg ctgagtcata tcaatagaga tgatgttggt
     1801 gtgcattctt ttgttacaga tagtgctgat tggcaaagtg tcattgagtt agattccttt
     1861 tttgaggata ttatggtttg tcaagacttc gatgaatttg aacaggtttt acaatccgac
     1921 tctaaaatta gtgctattga tgttgctaaa tttttcttag caatgcgtcc actctcacac
     1981 ttacaattgc aaaagttagt ttatcttgct tataaaacat atcttcttgc ctatggtgaa
     2041 tccttatttg atgaaaaaat agttgctttt caatatggtc ctgtagtaga agaggtgtat
     2101 cacagcttta aaaaatatgg ttctgaggtg atagatatcg atgatcatac agaatatatt
     2161 ttaaaagaca tacatcttcc gcaagcctta ggtagaatgc tattggtcga agacgcaaag
     2221 aagattgtgc ctgtattatt agatgttgtt aaacagtatg gagatttaac aggaggagaa
     2281 ttggttaagc tgacgcactc tgaaaaggga ccttggcaga cggtttttcg tccacagtta
     2341 aattgtgaga tcactgatga ggttatttta gcccaaggca gatatgaaag attatcatca
     2401 taagtacctt tgcttattgt attagctgag aatactcagt tgtctcatca aaaccaaaac
     2461 aaaaaagcct ttgaaacgtt gatttcaagg gctttctgta tatcgtctta ttttacctct
     2521 gtaaacacaa catgtttacg tagttttggt gagtattttt tcaattgaag gcggtctgga
     2581 gtgttacgtt tgttttttga agtaaggtac aagcgttcac cagattcttt gtgttcaagt
     2641 gtgatattta cgcgcatggt atctcccttc tattattcag ctgcgttagc tttagcgatt
     2701 ttatgtcctt tgtagtatcc cttaagtgag acacgatgtg aacgtgagta atctccagtt
     2761 gtttcgtcaa attttactga tggtgcagtc aatttgtagt gtgtacgacg tttgttcttt
     2821 ttagcttttg acgtgtgacg tgcaggaact gccatttttt ctatcctccg ttaaatgatc
     2881 aagggtctat taaaagattg gtgacaaact ggtgtgcatg atcttatgct aacctatctg
     2941 tctcaaatct ttgacccatt gttatctatt tgatgttatg gctttcgcca actttagtat
     3001 catatcatat cttctatgta aagtaaagtt acttgacaaa aattttatta aaaagctctg
     3061 ctattctcca aaaatcctaa aaaatggtaa aatgagacaa aggtggttat tttaggagat
     3121 taagatgttt ggaaaattat taagtctgtt aggctttgtc gttgctttga ctggttgtgg
     3181 tgtttcacag gcagaaaaag aacgtgttgt aacagagtat agccccatta ttattaaaaa
     3241 atttcaaacc ttaggatacc aagggaaaat cactgtagac gactatacta agatgattga
     3301 gacaggtagt gagagacttt attttaccta cagcgaagaa gtagacggta aggttattag
     3361 tctgaaggat agtatttcga ttgctaccta taaatcacct gaggaagatt tggctgatgc
     3421 agaagttgac atgggaatta gggaagaagc tatgtggcag caaccagctg tcaaagcgca
     3481 agctgctcag atcaaacaac tatttagcga gttggagact gaggatttga agcttatatc
     3541 cgtaacagga caaagtgtcc agacgatttc tgattcagat ggagagctga ttagggaaga
     3601 tgttgtacga ggcaggaatg aattatctca agatgcatct aataatagag aagctgggct
     3661 atcaataggt ggctattatc atattgatgt ttcaaagtat ttgaaaaatc acgtgttgga
     3721 aattcgtata gattttgatt ggcgaatgtc agaagaggaa caagacgatt tgtctggccc
     3781 caggttggat ttttctgata gaataaaaag tctagacttt acctgcttgt gggatggcta
     3841 ctataaagtg gggtttgaca gggtgagtag atctaatcga agtggagata ttcaagatat
     3901 gattgtttta gatattcgag gcggtaaatt ggttcgtagc ttttctgtac tttaacagat
     3961 taatgaagct attctatggt aaaatatata aatactagta aaagaggaaa taaaatgaag
     4021 cttcaaaaac caaaaggaac acaggacatt ttgcctgtgg ctgctgctaa gtggcaatat
     4081 gttgaaggtg ttgcacgtga aacctttaag caataccatt atggtgaaat ccgaacacct
     4141 atgtttgagc attatgaggt cattagccga tcagtaggtg ataccactga tattgtgacc
     4201 aaggaaatgt atgacttcta tgataagggc gaccgtcata tcacacttcg tccagaagga
     4261 acagccccag ttgttcgttc gtatgtggaa aacaagctct ttgcgccaga ggttcaaaag
     4321 cctgtcaagc tgtattatat tgggtcaatg tttcgttatg agcgtccgca ggccggccgt
     4381 ttgcgtgaat ttcaccagat tggtgtagag tgctttggct ctgccaatcc tgccactgat
     4441 gttgagacga tcgccatggc ttatcacctc tttgaaaggc ttggtattaa agaggtgacc
     4501 ttgcatttga atagccttgg aaatgcagct agtcgcgcag cctatcgtca ggccttgatt
     4561 gattacctat ctccaatgcg tgagaccttg tccaaggata gtcagcgccg tttagatgaa
     4621 aaccctctgc gcgtgcttga ttccaaggaa aaagaggata agattgcagt agcaaatgcc
     4681 ccatctattc ttgattatct tgacgaggag agtcaggctc actttgatgc tgtgcgcagc
     4741 atgcttgaag tacttgctat tccttatgtt attgatacca atatggtgcg tgggcttgat
     4801 tattacaacc acacgatttt tgaattcatt acagaggtgg atcagtctga gctgacgatt
     4861 tgtgctggtg gtcgctatga tggtcttgtg gagtattttg gtggaccagc aacccctggc
     4921 tttggttttg gacttggttt ggaacgtctt ttgcttatcc ttgataagca aggcgttgaa
     4981 ctgccagtcg aagaaggctt ggacgtttac atagctgttt taggggctta cgccaatgtg
     5041 gcggcgctag ccttgacaca ggccattcgc cgtcaggggt tcaccgtaga acgcgattac
     5101 ctcggacgta aaatcaaagc acaattcaag tcagctgatg ctttcaaggc aaaggtagtc
     5161 atcaccctag gtgaaagtga aatcaaaaca ggtcaagctg tccttaagca taatcaaact
     5221 cgtcaagaga tgacagttag ctttgatcaa atccaaacaa attttgccag catttttgca
     5281 gaatgtatcc agtaaagcaa aaaaactgaa aaaagtggta tgagtcatta agatactaaa
     5341 aaatcacaca acgtcgttgc tttaatagca atgatattgt gtgattttgt gatgttatac
     5401 ctatactaag gactattttt cctattttta gtagtcagtt tgaaagcact cttgtttgga
     5461 atggcagcag ctatgcttat agctggtgat gggttaatgc tattgttgag aaactaaaac
     5521 aatgttagag aagataatgc tgactttata gatgttattg tctatggttt gctggtatag
     5581 tccataatac tgttgaacaa ttttttgaac atttttaatt cccaatccgt cttttttccg
     5641 ttgacttctg gaagcaagct cttttggatc aaaaaagttt tcgatatcaa tgtggagttg
     5701 atttttaaag agtctcacct ttaattgtat ttgtttttca gctttatttt gattgcgaat
     5761 agttgcggca atgctattat caagtagatt tcctataatg actgaaataa cttcagtctt
     5821 taggcttatg tttgtaggga taaggcagtg aatatctaac acaatgccat tctttttggc
     5881 tacgactgct ttttgattaa gtaaataatt taaaatagta tcattggtaa agaaagtatc
     5941 tgtcccatct agcaggttaa ggttatgatt cagtaattgt tgggctttag tgtactgctt
     6001 ttgctccaga agtcctaata ggacaatgtt ttgattatgt agatcatgct taagagccct
     6061 aatgcttaat tgattttcct ttacattttc taaatgcttc agttctgact ggaatcgtac
     6121 cctatctaag ttaatgtctt gcatttgtaa atgctgatct gaaatgtaag tatacagata
     6181 cagcgaagtg attgtgataa tgataaatcc aagtgttagc agtattgtaa acaagtcaaa
     6241 taaaggttct tcttttaatc gaaggagctg tagcagtagc agagaaagac ttatcattgg
     6301 aataatagat agctttagta tccagttggt ttgtgtttgc tcatcaagcc aattgtctgt
     6361 agtctttaaa aagagctgct ttaacacaaa tataatgata atactggata tggtaagcag
     6421 gtttataaat aaaaatgtcc cactgataga agagatttga tatttaagag atattaaaat
     6481 gatccctaag cttgcttcta gcaggatacc tatgctttga agtgtaacag accaaaagat
     6541 acactgtttc atggagtaac gatagctact agatattatc agtgatgtta ccaaagaaca
     6601 agtcagggtt atcagtgagg catagcttcc tgatacaaaa aaatgagtgc agcattctat
     6661 gaatactaaa aaagagagat aacctatgtt tttaaaggta gctagctgac catttttctg
     6721 acgaaaaaaa taattaacaa tcacaatatt aacaactgat gtataaagat gaaaaatagc
     6781 gttaatagcc atttactctc cttagcttgg aaaagatgtt ctcctgaata cccttcttaa
     6841 atttccgact gataggaatg ataaaaaagc gcgtgttatc aatagctaat gttatgtcat
     6901 tgttttcaaa tttatagaag taattgacgt taaacacata agaatgatgg gtttggataa
     6961 attgttcagg aagctctttt agtaatgctt tggttgataa aaaggtagag taggtcttgt
     7021 ccttggtatg aatgagtact tttcgtcctt ccttttcaaa atagataata tcgtttaagc
     7081 ttaagctata gtaggagtgg caagatgaaa aggtaaaaaa ttttttgtca agctctaaaa
     7141 cccttagagc tctatttagg cactcaaaaa aatagggttc atttaaaggc ttaatcaggt
     7201 aatcaaaggt ttgcacgtga aaaatgtttt ccatgtattc tttgtggctt gttaaaaaga
     7261 taataatagc agagagatta tctttcctaa tatgctcggc taatgctatt ccagacatgt
     7321 tatccatttc aatgtcaaga agaaaaatat ggtaatcatt agacagtgac tgtattaatt
     7381 gacaaggatc ctcgtaaatg tctaactcca ctggaactaa ttgattatat tggtataata
     7441 gatcttctac agctgttgca aaagctttat tgtcatcaca aagagcaatt ttaagcatgg
     7501 tacccccata atcctataga ctgtggtatt tagtatacca aaaatgacat gaaaagcgct
     7561 attttttaca aaataataat aatagactga atgttttgat aaaatgaatc tatgaaatga
     7621 gggagcaata atgactgaag taacagtgcg taaaccgatg gaaacaatgg aagtttcatg
     7681 ggtagtcatt taaatactct aaagtgggct gtttttatca gcctacttta atatttttag
     7741 gagggtaaaa aatgaattat agcagacctt gtattaaaga tatttatcca atttataaac
     7801 tgagtgatac catgtttcga ataggcgctc aaattaatat tacgacggaa tttaacgatt
     7861 caaattatga aacaggtgct tcatttacac ataagctttg gccacatttc aaagagtgtc
     7921 cggcttgtgg tcatggcaac agtaatgatt gggaaatatt tagtcattat gggtaggagt
     7981 taatcaatgg aacaatatga attaatggtg aggtcacttt caaaaaggta tgccagagat
     8041 ggctcttatg ccaataggga tttacattgt gtctttaaat ccagtgaaat aacagccttg
     8101 ataggtcata atggagctgg taaaacaact ctactaaacc agattattgg taatataaaa
     8161 cctgatgtgg gtgatatttc atttctagac tgttcgtttg tcaagtcccc taaaattgct
     8221 agaaaaaata cgtcaatgat gcctcagcta catgccccct taaaaggaat cacaattaaa
     8281 caggctattt catcaattgg aaaaatcaga gggctgtccg gaaaattatt ggagacagag
     8341 gttcaggaat taattcaaga actcggtctt attaagtggc aaaatactgt cggagagaaa
     8401 ctctctggtg gactaaaaag attgacgtcg tttgcaatgg ctgttattgc tgctccgaag
     8461 attgttttac tagatgagcc gacaaatgat gttgatccta taagacgtat aaaattatgg
     8521 ttatacttaa aaaagatggc ggcaaaggga catatcgtta ttgttgtcac ccataatatt
     8581 ttagaggttg aaaaatatgc agatgcttat tatttgcttg aaaaggggga agtaaaaagt
     8641 tcaggagcgg taaaaaccct atccagcaat ccaaagagta gaatatccat tttatttaga
     8701 gatcaaaaag ccttggaaga atacccattt gcttactcac ttggtgggga tgacaatgaa
     8761 gctataacaa taatggataa taaggaaatg acagcattat tgaattggtt aggcatacat
     8821 ttgtcatcag ataccattgt tcaatatagt atcacgacgt tagggttaaa tgattattat
     8881 gaggagctgt cagatgaaga agattagtgt tacttaccaa tttctaagct tgttaaattg
     8941 gagctttatt cgccataaat cgttgatatt attgtgtagc gttattcaat tttttatgac
     9001 aattgcactg gtttacggtt attcacttat tattgctgat gatactgtgc aaacagtcta
     9061 ctatcttgct tctggctcag taacgattgg tatgattacc attggctgta cggtatcagc
     9121 acaatcaatc agtagtgata aaagagatgg cattgtgagc tatattcaaa cgttacccgt
     9181 cctaagaagt ttgatcctgc tatctgatct attgatttgg acattaactg ctttgattgg
     9241 tgttggtgtg tcaattgcgg ttgtttattt aaaatttcaa atattgcccc agctgtcctt
     9301 agcgacgttt cttattttgc cattagtttt aatgacaatg atcagtatgg gttttgccat
     9361 tgcttattgg tcaactccaa gtacgatgat gctggtaacc caattattgt tgatgattgg
     9421 cttattgttt tcacctataa tgtatcctgc agaacgtata cctgaggtga ttttaagggg
     9481 atatcatttt ctgccattta taccagcagg agacttgatt cgagagacgg tttatttggg
     9541 gcattccatt tcagttgtca agcttgtggt gttactgtta tggctggttg ccactgcctt
     9601 actttcagtc aattggctaa acaggcaaag ctaaggtata ggctctgcta tttcttaaaa
     9661 actctactca aatgggtggg gtttttaatt gttttttgtt ataataagtg gtaatgatat
     9721 ttttaattag agaaaggaac aaagacaggt agggagtgtt gactctttat ttgctcttgg
     9781 tatcttattt atgaagcgta gcatgtatgc aggacacgtc cgaaaggaac atattggaag
     9841 aacgattgtt ttaaaaggtt gggtaagtcg ccgtcgtgat ttgggcggcc ttattttcat
     9901 tgatttgcgt gatcgtgaag gagtgatgca gctggttatt aatccagagg acgtttcagg
     9961 tgatgtgatg gcgactgctg agcgcttacg cagtgaatac gtgattgagg tggaaggaag
    10021 tgttgaggcg cgtcagcagg ctaatgataa gctagctaca ggtgcagtgg agctaaaggt
    10081 ttcaggcttg accattctta atacagctaa aacgacaccg tttgaaatca aggacggtgt
    10141 tgaggttagt gacgatacgc gtttacgcta ccgttattta gatcttcgtc gtccagaaat
    10201 gctggaaagc tttaagcttc gtgccaagac gacgcatgtt atccgtaatt acttggataa
    10261 tcttggattt attgatgttg agacaccgat gttgacaaag tcaacgccag agggagcgcg
    10321 tgattacctt gtaccaagcc gtatcagcca gggacatttc tatgctttac cgcaaagccc
    10381 acaaatcaca aagcaattgt taatgaatgc gggctttgat cgatattacc agattgttaa
    10441 gtgcttccgc gacgaagatt tacgaggaga tcgtcagcct gagtttacac aggttgactt
    10501 ggaaacgtca tttttatctg agcaagaaat ccaagatatt gttgagggta tgattgcaaa
    10561 ggttatgaag gatacaaagg gcatagaggt taagctgcca tttccgcgca tggcttatga
    10621 tgacgccatg aatcattatg gctcagataa gccagataca cgctttgata tgcttttaca
    10681 agacttgaca gatcttgtca aggagattga ctttaaggta ttttctgagg cacaggctgt
    10741 taaggcaatt gttgtcaaag gacatgcgga tcgctactcg cgaaaggaca ttgataagct
    10801 gacagaattt gctaagcaat ttggtgctaa gggtctggca tggctgaagg tggttgatgg
    10861 tgcatttact ggaccaattg ctaagttctt gacaggtgtg aaaagtaagt tgacagagtc
    10921 tttacagctt gagcataatg atttggtctt gtttgttgca gacaccttag aggtagccaa
    10981 caatacccta ggtgctcttc gtacacgtat tgcaaaagag cttgacatga ttgacatgtc
    11041 tcagtttaat ttcctatggg tggttgactg gcccatgttt gaatggtctg aagaagagga
    11101 gcgttacatg tctgctcatc acccatttac attaccaaca gcagagtcag cccatgagct
    11161 agagggtgat ttagccaagg ttcgcgctgt tgcttacgat attgtcttaa atggctatga
    11221 gcttggtggc ggaagccttc gtatcaacca aaaagacatg caagagcgta tgtttagagc
    11281 actaggcttc acagctgagg aggccaatga gcaatttggc ttcttactag aggctatgga
    11341 gtatggcttc ccaccacatg gtggtcttgc tattggtctt gatcggcttg tcatgctgct
    11401 tgctggcaag gacaacattc gagaggttat tgcctttcct aaaaacaata aagcatctga
    11461 tccaatgaca caggcgccta gtctggtatc tgaaaagcaa ttagaggagc ttcagcttca
    11521 aatagaacat catgattaaa aaaacaacct ataggaaaag agtaaaatac ctgattaata
    11581 gaggagccaa aaaaattggc ttgcttcatg ccgtaaaaag catttccaag gagaagtata
    11641 cagagaaaat ttcggcctct ttactctatg gcatattgtc tagtatagct gttaatttct
    11701 ttttccaacc gggccatgtc tactcaagtg gtgcaacagg acttgctcag gttatctctg
    11761 ccatcagcca ccatttatgg ggctttgaga ttcctgttgc tttagctttt tacgtgacta
    11821 acattcctct tttagtctta gcttggtata agattggtca taaatttacg atttttacct
    11881 ttattaccgt tagtatgagc tctttcttta tccaaatcat gcctcaggtg accttgacga
    11941 ctgacccact gattaatgct atatttggtg gcttggttat gggtttgggg atcggtacag
    12001 gcttcaagtc tcgcatttct agtggtggta cggacattat cagtctgaca cttagaaaga
    12061 aaacaggaaa agatgtcggt aacctttcat tgatgatcaa tggtgtgatt atggcttttg
    12121 caggactgtt gtttggctgg cagtatgcgc tttattcgat ggtgactatt ttcgtttcta
    12181 gtcgagtgac tgatgcgatt tttaccaagc aaaagaaaat gcaggcgacc attgtgacca
    12241 gctgtcctga caaggtgatc cacatgattc ataaaaagct gcaccgaggg gtaaccagta
    12301 tcaatgatgc tgaaggcacc tacaagcatg agcataaggc tgttttaatt acgattctca
    12361 cacgtgagga atatagtgaa tttaagtggc tgatgcttaa aacagatcca aatgcttttg
    12421 tttctgttgc tgaaaatgtt agaatcattg gtcgctttgt cgaatcagat gaagactaag
    12481 aaataggtat caatatgcca gctaataaga gcttaaagct taaaaattgt tgttttatta
    12541 ttcttggctc agctatttat gcctttgcct ttgtctactt ttacatggca aatcgtattg
    12601 ctgctaatgg gctagcggga ctgacgcagg ttgctaatgc cttgtttcag atcaatcctt
    12661 caataacggg ttatctgatt aatttgcctc tcgtcctgtt gggtgcaagg ctctttggca
    12721 gacgggcaat ggtgtatact gtgaccggta ttttatcact ttattggttt gtttggctgt
    12781 ttcaacagct cccccttttt attgacttag atcatgacaa tttagtagtg tccttgctgg
    12841 caggaattct tggtggttta ggtggcggca ttgtttttag aaatggtggg acgattggtg
    12901 gctcagatat tattgctaag ctgatagagg ataggtttgg cttgcagctc aatcaagcct
    12961 tattagggat tgatattttt gtcattgtgg tttctttgac ctatatttca ataccgcaga
    13021 tgatgtatgc tttgattgct agctttatgt atagtaggat tgttcatctg gtgcaaaatg
    13081 gtggctattc tgcacgcgga acctttatta tttcagatta ttctcagact atttcacaat
    13141 tcattatgga ggagctcggt agaggagtca cctatttaca tggtgagggt gcttactctg
    13201 gtcgtgagaa acaggttatt tatgtagctc taggtcgatc agatgtacga gagctaaagg
    13261 cctttatagc acaggttgat cccaatgctt ttgtttcttt ctttgatgtt aacgaagtca
    13321 atagtccaga atttattgcc acaaaaagta aataccataa aacgaaaaaa agataaaggc
    13381 tggaatatca cattcatagc ctttgattat gctaatgaaa gcgcttggct attaagctta
    13441 ttgtagtgta gctattaaat ggccgtcctt gagctttcat ctggtaccta acaaatgtaa
    13501 tgaatagtga ggaaagtgaa tgacaaatct tgacaaatgg catcgtgtaa gagagctatt
    13561 attaattgcg gtgggtgttg ctatctatac ctttggtttt gttaatttca acatggctaa
    13621 tgaattggct gagggtggcg tagctggaat taccttgatt ttgcatgctc attttgggat
    13681 caatccggct tattcgtcac ttttatttaa tctgccttta tttatgttag gggctaagat
    13741 ttttggaagg cgctccctag ccttaacgat ttatggaacc gttcttatgt cagtctttat
    13801 ctggctgtgg caaaaggtgc ctatggagct tggtttagag aatgatatga tgcttgttgc
    13861 ggttgttgca ggcttgtttg caggaattgg tagtggcctt gtttttcgat atggagcgac
    13921 aactggtggg actgatatta ttgcccgcat tgcagaggaa aagtttggtg ctaagctggg
    13981 gcaaaccctg ttatttgtag atgccttggt attaacagcc tctctcactt atgttgattt
    14041 gaagcatatg ctctatacat tagtggctag ctttgtcttt agccagatga ttagtgttgt
    14101 tcaaaatggt ggctatacca ttcgtggtat gattattatc actaagcagt cgcaagccgc
    14161 ggcgcaggcg atcttgacag aaatcaatcg aggagtgact tatttaaagg gacaaggcgc
    14221 ttattctggt catgattata atattatgta cgtgacgctc aatccaacag aggtgcgaga
    14281 ggtgaagcgt attttagcag agctagatcc agacgccttt atctctatta ttgatgttga
    14341 tgaggtaatc agctcagact tcaagattcg tcgcaaaaat tttgacaaac caattgagaa
    14401 ggctttacag aaaaaatcca acatgttaaa ataaagaaaa taagcagaaa taagaggttg
    14461 agaaaagcca tgattaacaa ttaactcatt gtcaagcact aatctatgat taacagcaag
    14521 ggattagtgt ctgctttgag gcttgggaat cagggctttt tgtgtgcact ttttcaggcc
    14581 tttctgatga tagaaaggaa taaatatgga agcacttagt attcagcatt acgctttaga
    14641 tacagcagaa aaaaacttat tgacaataga ttctcttaca ttgaatcaag gtgagagggt
    14701 tttcatcatt ggtgataatg gggctggaaa gaccagcttt ttaaagacaa ttatcggaga
    14761 aagcactaac tatagtggct ttttgcaggt gcatggagat attgcttatg ttccgcaaat
    14821 caagtccact agccctcagt caggaggtga gagggcgatg tcttacctaa aagaggcttt
    14881 tcaagcaagg ccttctctgt taattttaga tgagccaagc tcttatttag accatgctaa
    14941 tcgtgattgg ttgattaatc aattgaaacg ctaccgagga accttgctgg tggttagcca
    15001 tgatcggtat ttgatcaatc aattgagtca gaaaatatgg ttgcttgagc atcaaacgat
    15061 caagacttac catggcaatt atgatgatta tcagcgttct agacagctag aggaggataa
    15121 gcagctaaga gcttttctgg aataccaacg aaagactaat caactgaaaa aaagcctgac
    15181 cagaaaaaaa gtgcaggcca acaaaatggc tgtaaagaaa aagtcggttt ctcggtcaga
    15241 ttggaaaacc aattcctttg cgggcagcta tgattcacag gccaaggcta tggcaaaagc
    15301 agctaaagct atggaaaatc gactcactcg aatgaaagag gttaacagtc cgcgcaaaaa
    15361 ggcttgggca aaattaaaaa aggatccaaa cgaaggtgca ctaccaaata ctcttttaca
    15421 cctacaagaa ggtaccctta caagggacca tcagttattg tttgactatc ctggtattgt
    15481 gatcagatca catagcagga tagcgattat cgggagaaac aaggctggta aaagcagctt
    15541 tttagatcag ctggcagccc aggccttgtc tggattttat gcgcaaaatc taaggataac
    15601 ctattttaaa caggaccagg ctgacttgga gccggatcag acagcagtag agctcattag
    15661 tcggcagtcc agccaagata gggtcaccat tttaaattat ctagctatga tgggcattga
    15721 ttatgataag gccaatcaaa aggtagctgt cttatctggt ggggaaaggg ttcgtttggc
    15781 gttagtggct gccttgctga cagatcatca gcttttgatt ttagatgagc cgacaattta
    15841 tttggatctt gtcgctattg aggctttgga gtcttgcttg attgactatc cagctgctct
    15901 tttgttggtt tctcatgacc tagcatttgt taacaaggta gcaacagaaa tttatgaggt
    15961 taaggatcat catttaacag cctatcattt tgaagactag caaaaaagcc taggctagct
    16021 tatcctcgct agcttaggct tattagtcta catttcattt ggtgcctcaa cacccaatag
    16081 acgaagcgct tctttgagga cgattgcagt tgcatagcaa agcgctaagc ggttgtcacg
    16141 ttctggatcg tcttcgagga tacgggtatg cgcataatat ttgttaaagc tttgtgccaa
    16201 gtgaatagca aattttgcca tgattgatgg ctcaaagtta tcaaaagcac gcttgatgat
    16261 acgtgggaag tcctggataa gcttaatgat ttcccagctt tcaggatcat taaggctata
    16321 gcttgtatcg gtagctggcg taaagcttgc tttacgcagg atagattgga tacgtgcgtg
    16381 tgcatattgg acgtaaggac cggtttctcc ttcaaaggat accattgctt caagatcgaa
    16441 gtcatagcca ttcatacggt ctgtttttaa atcatagaac ttgatagctc ccacaccaac
    16501 agcatgagct actgcttcct tgttggcaag cttaggattt ttagcttcga tttggtttgc
    16561 tgctctgctg atggcttctg caaccgttgg ctcaagcaaa atgacattac ccttacgtgt
    16621 tgataatttt gcaccgccct ttgtcacaag gccaaaagca acgtgtgtca tgtcatctga
    16681 ccaatcgtag cccatttctt taagaacagc ctttaattgc ttgaagtgtg cagcttgctc
    16741 gttgccaacc acgtaaactg attttgcaaa atcataggta cgcttgcggt aaagggcagc
    16801 agctagatca cgagtaatat aaagcgtagc tccatctgat tttttaatga gagctgggtg
    16861 ctcaatacca tatttttcaa ggttaaccac cttagctccc ttagattcga ctagtaggcc
    16921 tttgtcctca agaagctcaa ggacctcatc cattttatca ttgtagaagg cttcaccatt
    16981 atagctatca aagctaactc ctagctggtc atagagtcgg ttaaactcaa tcaagctttc
    17041 atcgcggaac cactgccaaa gctctgtagc ctcttgatct ctctcctcta gcctgcggaa
    17101 ccattcacgt gcctcctcat caagactagg atcagtttct gcctctgcat tgattctcac
    17161 atagagcttt aagagctcat caattgggtg tgcttgaaca gcggcctcat ttccccactt
    17221 cttatacgct acaatgagca taccgaattg cttgccccag tcacctaggt gattgatttt
    17281 aacaggctta tagcccattt ttgcaaagat atgagcaaga ctgtccccga taactgttga
    17341 gcgcaggtga ccgattgaaa atggcttagc aatgttaggg ctggacatat caatagcaat
    17401 atgacgtcct tgtccttcat cctgttgagc atagtcagct ccgtcagcaa tcacctgtgt
    17461 aagaacctgt gcagaaatgc tagccttatc taaaaagaaa ttgacataag gaccaacagc
    17521 agcaaccttc tcaaattggc tggcgtcaat cctttcagct aaatcactag caatagcttg
    17581 tggtgctttg cgaagcgcct ttgctagact aaaggctgga aaggctaagt ctcccatgtc
    17641 agaatttttg ggtgtttcaa gtaagttaaa aatggcagcc tgctctagtt caggaacaat
    17701 cttagcaatc tcagctgcaa tcagagtttt agtgtccata ttgcttctcc taaaaatagt
    17761 ttgtcaccct attctaacac atttcttgga aataaacgag gtgtctattg agaaattata
    17821 ctagaaggct tgtaggtgtt ttggggaaca aagctaaaga attagagcag caaagcttgc
    17881 caaatctaag ggtctaatga tatgagcaag aaataatgct tccttaaaat aaagcaaatt
    17941 gacagagctg agatgaaata ctaccatttt tttgttataa tttgagagga taattataca
    18001 ttggggagat atatcatgaa taaaatagaa cggcagcagc aaatcaagca acttattcag
    18061 gctgagcaca tcggtacaca ggaggagatt agacggcttc ttcaaaagga tggtatcgtg
    18121 gtcactcagg ctaccctatc acgagattta agagaaatcg gattacttaa attaagagat
    18181 gacagaggta agctatacta tagtctttct gagcctgttg ccacaccatt tagtccagat
    18241 gtgcgctttt atgtcctaaa ggttgaccgg gcgggcttta tgctggttct ccataccaat
    18301 ctgggagaag cagacgtgtt ggcaaatctt attgacaatg atgccattga ggacgttttg
    18361 ggcacgattg cgggtgctga taccttactt gttatttgtc gtgatgagga gattgccaag
    18421 cgctttgaaa aagatttagc tgctggtcta taatatgcct taccgcgaat ccttacatca
    18481 gctgatagca gcactggaaa agcactcaag cattatagct tataaggagg ctcagcagca
    18541 cttgcttcaa aggactgatt ataatcaaaa ggcctatcag atgaagcgac atcaacagga
    18601 cacctatctt tttcgtcaaa tcgctaagga taaagcagct gaagaatcag cttttaaggc
    18661 tcagcaatta cgagaagatt tagatcatca accattgata gatgattatc gtgacaaaat
    18721 gcaaaacgct agtgacttgg ttcggtacat tacagggact atagaagatg aattaaataa
    18781 ggagttcaat gatggcaaag gctaatgttt ctcccggaat gcagcagtat ctggacatca
    18841 aaaaggatta tccagatgct tttttgcttt ttaggatggg agatttttat gagttatttt
    18901 atgaagacgc tgttaaggca gcgcagattt tagaaatcgg cttaaccagt cgtaataaaa
    18961 atgctgacaa cccaattcca atggcaggtg ttccctatca ttctgtccaa caatacatcg
    19021 atgttttaat tgatttgggg cataaggttg ctattgctga gcagatggag gatcctaagc
    19081 aagcggtcgg tgttgttaag cgtgaggtgg ttcaggtcat taccccaggg acagctgtgg
    19141 actcaagcag acctgatagt cccaataatt ttttggtggc tgttgatttt gatggcaagg
    19201 cttatggcct gtcttatatg gacgtctcta caggagaatt ttttgctaca gacctagcag
    19261 attttgccag tgtcaaaagt gagattcaaa acctgaaggc aaaagaggtt cttttaggct
    19321 ttgaattatc tgaagaagag caggctattt tagtaaagca gctgaatctt ttgctgtcct
    19381 ttgagatgac agcactagag gattcgcctt tgattgatca tcagctaaca gcagtcgagc
    19441 tgtctgcagc aggtaagctg ctacactatg ttcatcaaac ccagctgcgt gagcttagcc
    19501 atctacaggc cttggtgcac tatgatatta aggattattt gcagatgtct tatgcaacca
    19561 aatcaagcct tgacctgctt gaaaatgctc gtactggtaa aaagcatggg agcctttatt
    19621 ggttgcttga tgaaaccaaa acagccatgg gtatgcgtct attaagggct tggattgata
    19681 ggccacttgt gactagtgag gcgatcctag aacgtcagga aattatccag gtgtttctta
    19741 atgcttttat cgaaaggaca gatctaagcg atagtttaaa gggtgtttac gacattgagc
    19801 gcttgtctag tcgtgtatct tttggaaaag caaaccccaa ggatctatta cagctaggtc
    19861 atactttggc caaagttcct tatatcaagg ctatcttaga ggcctttaac agtccttacc
    19921 ttgacaagct tgtcaaccaa attgacactt tgcctgagct agagcacctg atacggtcag
    19981 ctatagatcc agatgctcct gctactatca atgaaggcaa tattatcaga acaggctttg
    20041 atgaacggct ggatcattac cgaaaggtca tgcgagaagg caccggctgg attgctgata
    20101 ttgagacaaa agaaagacag gccagtggga taagcaatct caaaatcgac tataacaaaa
    20161 aagatggcta ctattttcat gtgaccaact ctaatctagg tatggttcct gaccattttt
    20221 ttagaaaggc aacattgaaa aattctgagc gctatgggac agcagagcta gctaagattg
    20281 aaggacaaat gcttgaggct agagaggagt catctagcct ggaatatgat attttcatgc
    20341 gtattcgtgc tcaagtggag acctacatcg ataggctgca gcagctagca aaagctctag
    20401 caactgttga tgtcctacaa agcttagcag tggtcgcaga gaagaatcac tatgttcgac
    20461 cattatttaa tcaagagagc aagattgcga ttgacaatgg tcggcatgct gttgttgaaa
    20521 aggttctagg tgttcaggag tatattccaa acagcatttc ctttggtcca cagacaagca
    20581 ttcagctcat tacaggacca aacatgagtg ggaagtctac gtatatgaga cagcttgctt
    20641 tgacagtcat tatggctcag ataggctcat ttgtagctgc agaatctgct agcctgcctt
    20701 tatttgacgc tatttttact aggattggtg cagtagatga tttgatctca ggccagtcta
    20761 cattcatggt tgagatgatg gaggctaatc atgctatcaa gcgagcaacc cctcattccc
    20821 tgattttgtt tgatgagtta gggcgtggta cagcgaccta tgatggtatg gcactagccc
    20881 agtctatcat cgaatacatt catgatagag ttggtgcaaa gactatgttt gcgacccatt
    20941 atcatgaatt gacagagctg tcaaccaagt tgacaaagct ggttaatgtt catgttgcga
    21001 cgttagaaaa agatggaaat gtaaccttcc tgcataagat tgccgaaggt cctgctgata
    21061 aatcctatgg gattcatgtg gcgagaatag ctggattgcc agaggattta ctagccagag
    21121 ctgatactgt gctaaccaag ctggaagctc aatcacaagc aagagagtcc gtcttatcaa
    21181 ctacagaagt aagagagact cagcagctgg ctaatcagca gctatcactt tttacagatg
    21241 atggctcctc tagcgagatt attaaaaggc ttgagagtgt tgatgtgatg aatctaactc
    21301 ccattcaggc catgaccgtt ctttatgagc taaaaaagct actgtaaaag ctagtatcag
    21361 atgttaaagg cacttgtagg ctcaccaggc cacaggtgct ttttggttta ttgaccataa
    21421 gacccttgct agctctgatg cttggctctt ttagttttat gttataatag tccataagaa
    21481 tgcgaggaaa tatatgacaa caattatcga attacctgag gttctcgcca atcaaattgc
    21541 agctggtgaa gtcattgaaa gaccagcaag tgttgttaaa gaattggttg agaacgccat
    21601 agatgcaaag agtagtcaga ttactgttga aatagaagag tctggcttga aaatgattca
    21661 aatcactgac aatggcgaag ggatgtctca cgaggacctg cccctgagcc tgcgtcgtca
    21721 tgccacaagt aaaatcaaaa gtcaaagtga tttgttcaga atcagaacac ttggctttcg
    21781 aggagaagct ttgccttcgg ttgcctctat cagtaaacta acgatcaaaa cagcaacagc
    21841 tgatgcagag catgggtcaa tattagttgc tagtggcggt aagattgagc agctggaagc
    21901 tgtctcaaca cctgttggta caaaaatcaa ggtagaaaac ctattttaca atacaccagc
    21961 tagactgaaa tacatgaaga gcttacaagc ggagctggct catgttgttg atgtcgtcaa
    22021 tcgcttgagc ctggctcacc cagagattgc ttttacattg atcagtgatg gcaagcagct
    22081 aacacaaacc tctggggctg gggatttacg tcaagcgctt gctggtatct atggcctgaa
    22141 tactgctaaa aaaatgattg acatttctag tgctgattta gattttgaag tgggaggctt
    22201 tgtgagtctg ccagagctga caagagctaa tcgtaattac attactatcc tgatcaatgg
    22261 tcgctatatt aaaaatttct tgttaaatcg agccatttta gatggttatg gctctaagct
    22321 gatggtggga cgctttccta tagctgtcat tgatattcaa attgatcctt atctggcaga
    22381 tgttaatgtt cacccaacca agcaggaaat tagaatttct aaggagcgtg aattaatggc
    22441 tctgattagt acagctattt cagagagcct acgagaacaa gacttgattc ctgatgcctt
    22501 ggaaaattta gctaggtcca gcacacgttc attttcaaag cctgagcaga ccagtttgcc
    22561 tttacagcct agtcagcttt attatgatcc gcaaaaaaat gatttcttta ccaaagaaac
    22621 agtggtttca gaggatagcc cgcagggctt taaccatgaa actttggttg acagtggtgt
    22681 caagcaggtt gacaatttgc agctggccaa gactgaatct gaagcagctg ctccaagtgt
    22741 taaatatgct agtcggccag atcctatgct ttctgatggt gagcacccgg gtcttgatgt
    22801 ccacaataag caaaaattat ctcagatgct tgatcgttta gaaaatgaag agcagtcggt
    22861 ctttccagag cttgattatt ttggccaaat gcatgggacc tacctttttg cccaaggcag
    22921 agatggcttg tttatcattg atcagcacgc agctcaggag cgcgtcaagt atgagtatta
    22981 tcgtgacaag attggtgagg ttgacaatag cctacaacaa ttgctggtgc cttatctgtt
    23041 tgagttttcc ggatcagatt ttattaatct tcaggaaaaa atgtcgcttt tgaacgaggt
    23101 tggtatttat ttagagcctt atggcaatca tacctttatc cttagggagc accctatttg
    23161 gatgaaggag gcagagattg aatctggtgt ttatgaaatg tgtgacatgc tgctgttgac
    23221 aaatgaagta tccatcaaaa cttatcgtgc tgagctagcg attatgatga gctgtaaacg
    23281 ttccatcaag gcaaaccata gcttagatga ttattcagca agacagctgc ttttacagct
    23341 tgctcaatgt aaaaacccct ataactgccc acatggtaga cctgttttga ttaacttcag
    23401 caaggcggac atggaaaaaa tgttccgtcg tatccaagaa aatcacacca gcttgagaga
    23461 attgggcaaa tactagagag gatagcatgc gagaattttt ccagttacct aagcaaatac
    23521 aaattcggca atttgtgcgc tttattacca ttacgcttgg cagtagtatc tttcctttta
    23581 tggcgatgta ctatacaagc tactttggcg ccttttggac aggcatacta atgatggtga
    23641 ctagctttac aggctttatt gggaccttat atggaggtca tttgtcagat gctattggtc
    23701 gtaagaaggt aattatgctt ggttcagttg cgagcacctt aggctggctg ctgaccattt
    23761 tggccaatgt tccaaagacg gttcttcctt ggttgacctt tgtgggaatt ttgctggttg
    23821 agcttgcttc cagcttttac gctcctgcct atgaggctat gctgattgat ttaacagatg
    23881 atagcaatcg tcgctttgtt tataccatta attactggtt tattaatata gccattatgc
    23941 ttggtgcagg tatttcagga cttttttatg atcggtattt cttagaactg ttgattgctt
    24001 tactgattat taatatcgtc tgctttggta ttgcctatcg ttattttggt gaaacgaggc
    24061 ctgagcatta ccgctttgag catggtattg gtattctagc aggttttgct aactaccggc
    24121 aagtctttaa ggatcgcgct tttgtgttat ttactatagg gacgatttta tttagcagta
    24181 tttggttgca gatggacaat tacgttccgg ttcaccttaa gctgtatttt gaagagactg
    24241 atgtgctcgg tattcatctg actagctcaa aaatgctgtc actgatggtc tttaccaata
    24301 ccttgctgat tgtgctgttg atgacagtta ttaatcgctt gacagcaagg tggagattat
    24361 taccacagct ggtgatcgga tcggttattt ttgcctttgg tatgctgttg tcatttacat
    24421 ttactggctt ttttgctatt tggtgttcag ttgtggtgtt taccattggt gaaatgctaa
    24481 atgtccctgc caatcaagtg ttaagagcag aaatgatgga tcagtctaaa attggctcct
    24541 acacaggctt tgtctcgatg gcccagcctt tgggagctat tctagcaggt ttgctggttt
    24601 ctcttagtca ttttacagga caggctggtg ttcagctagc atttgttttg attgcctgtg
    24661 tggggcttta tgtgattgtt ttatctgcga aaatgaagaa aaaggtgtag tatgtacgat
    24721 tatattaaag gtcagctaac aaaaattact gcaaagtata ttgtggtaga agcaaatggt
    24781 ttaggctata tgataactgt tgccaatcct tatagcttta cagactgtgt caaccagcag
    24841 gtaacgatct atcttcatca ggtgatcaga gaagatgctc agctgctgtt tggttttcac
    24901 agtgaggaag aaaaggacgt ttttttgaag ctgatttcgg tatcaggtat cggaccgacg
    24961 actgccctag ctattgtagc tgtagatgat aatagaggac tcgtcaatgc cattgataat
    25021 agtgatatta catatttgat gaggttccct aaaatcggaa aaaaaacagc tcagcaaatg
    25081 gtgcttgatt tagcaggtaa gttcgttgaa gcacctaagg aggaaagcag caagccccct
    25141 aaagccaagc aacaggggaa tgaacagctt gatgaggctg tcgaagccct attagccctt
    25201 ggatataagg cgacagagct aaagaaaatt cgagccttct ttgagggaac aagtgagaca
    25261 gctgagcagt atatcaaatc agctctgaaa atgctaatga aaggctagga gcttcatatg
    25321 aaacgttgcg catgggtacc acaagataat aagctttatt gtgattacca tgacttggag
    25381 tggggaaggc ctgtctatga tgatcgcgct ctttttgagc tgctttgtct tgaaagctat
    25441 cagtcaggct tatcttggtt aactgttttg aaaaaacgtc cagccttcag aagtgttttt
    25501 catcattatg atatctcagc tgtggcaagc tttagtgagc aggaaatggc tgctgccctg
    25561 caaaatgcag caattatccg acacaagcca aagctaatag ccactgtcaa caatgcagcg
    25621 gcagtccagc gcatccaaca agagtatggt agcttttcca gctatctttg gaactttgta
    25681 ggaggtcagc caattgacag gcttgtcaac gatgacaacc cagcgcccgc tcaaacagcc
    25741 ctatctctca agctatctaa ggacttgaaa aaacgtggct ttaagtggct aggaccaaca
    25801 actgtttatt cctttatgca ggcagcagga ttggtcaatg accatgaaga gaactgtgag
    25861 tttaggtaga attaatcgcc tctttggagt gatgtttcat gagcctatca aagagagctt
    25921 gataaaaaca gcccaatctt gattgcttat aggatgatgt ataagagcta tgtttttgct
    25981 ccgtacttta aggatagatg atgaatcccc ttatttaccc tgtagcgaat gttgtaagct
    26041 tctaatgggt ttaaggtttt agcctgttac tgctattgcc agtaagctac agtttgatca
    26101 ggtagttata ttggattgcc tcaacgattg tgttgctgct ggctggtgct tctttctata
    26161 acttattttg gtgcatgtga ttgtggctct aaaagttata acagagtatc ggtacgattg
    26221 gtgttacccc ttggtttcta tttttttctt atcagccagt ctggcattta cagcctataa
    26281 taaaagctac cgcttaaaaa tttcttagcg gtagtttttt agttcatgtt gcaaggtttc
    26341 tagaagttca gtttcttctg tcaactgtag taattgtaag cctttattaa ttaggtgatc
    26401 atcattacga caaataccga gacgaacttg ggaaaaacct aagctatcat agcgtttaag
    26461 ctgtctagct aatttgattg ttagtaaggt aatttcttcg cactcctttt tgaggttgtg
    26521 atagaggtaa atggttgaaa gattggttag taaagcatat tcagatgatt tgatattgcg
    26581 gtaatcttta tattttgcta ggctatctag gattttttga ctgatgtttt caattatttc
    26641 gataggaaag tgaaaaagaa tggtatgtag taattgtaaa tctttctcat accaagtatc
    26701 ttgttttacg agggaattcc agattttata agctagctct tgtaaatctt gattgttttt
    26761 aacgcctttt ttcctaagac ttatcatgac ttcgacacta tctaaaatat aagaaatggg
    26821 aatatcattt ttatttttaa ggtaattgaa gcatttttga cgtaattttt ctaattcagt
    26881 aatatttaca gctgatacct gattataaaa ttggtttaaa atgtcctgcc ttgtgctagg
    26941 atgataagtg ttgcagacat atctaaactc ttccagtgtc atattgagtt ggtttaataa
    27001 aaaaatcatt gtatcaaatt taggaatgac ttgtccgctt tcaatacgag ctagtgtaga
    27061 acgagctaaa aagtctccac agatcttttc ttgtgttaat cctttagatt ttcgtatagc
    27121 ttgataaatt ttaccgtaat cccaacg
//
LOCUS       DARYXW010000019        25899 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.019, whole genome shotgun sequence.
ACCESSION   DARYXW010000019 DARYXW010000000
VERSION     DARYXW010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25899)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25899)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25899
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.019"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            164..769
                     /locus_tag="TV191_000655"
     CDS             164..769
                     /locus_tag="TV191_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEL1507192.1"
                     /translation="MGSTLIDESLAFNAFMKQWRISLARCGKQLTREELLSSINMLTA
                     AGICEFDLLWQRLAPKGCQRPKWSHQLERLFADTKPCLQVLSETYQLGIIANQAKGLK
                     ERLERFGISHYFALMISSSDVGLQKPDLALFRYALDQAGVLARDAVYIGDRVDNDIIP
                     AKALGMRAVRIHQGLAASSPDDRLYPSDVHISKLSDLLECF"
     gene            1237..4017
                     /locus_tag="TV191_000656"
     CDS             1237..4017
                     /locus_tag="TV191_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEL1507193.1"
                     /translation="MSNKKFFTYASLLALIAVPTVVEEVTAQPSAQLVYADELRLSPS
                     TDSSPVTKTDEADQPVAQSVSATEPVEALVIADKESALNPAVLADADGSQPIAVVRAG
                     QEGQPYTVTGKIISAVNGWGGHGFYIQDSQGSGLYIYPGSALGYVTGDVVQLTGTLTT
                     YKGELQLKTITKHHKINGELPTPIAEVTIPELEKASPSTLVKLSNVTVGDISSDKHET
                     SSFKVSDTAGNSVAVRLDNRTGVKTSDLLSKIGKGDVINLTAIHSTFDGKLQLKPFSL
                     EQFEVVKKVVREEEVTPLGRVVKIGQIQGASHTSPLLNQAVTVKEVVVTYLDDATHFY
                     VQDINGDNDKATSDGIRVFAQNAQVQAGDVLTISGTVEEFFGKGYDDRKQTDLTITQI
                     KASKVTKTGTAQVPAPLVLGKDRVAPANIIDNDGFSVFDPEEDAIDFWESLEGMLVAV
                     DNAKILGPMSHKEIYVLPGSSTRVLTNSGGILLPETGYNTDLIPVLFKKGKQTIKAGD
                     SYQGRLAGPVSYSYGNYKVFVDDSSRMPVLVDGQLKPEKTHIKKDLSKLSIASYNIEN
                     FSANPSSTKDEKVRRIAESFIYDLNAPDIIGLIEVQDNNGPTDDGTTDATQSAQRLID
                     AIKALGGPAYQYVDIAPENNADGGQPGSNIRTGFLYQPGRVSLSDKPRGGVNDAVKWV
                     NGELSLSVGRIDPTNPAWNSVRKSLAAEFIFQGHKVVVVANHLNSKRGDNSLYGRVQP
                     VTFKSEERRHVLARLLSQFTKEGASQQANIVMLGDFNDYEFTKTIKLIEEGDMANLVS
                     RHELSDRYSYFYRGNNQTLDNMLVSRNLLGRYEFDMVHVNSPFMEAHGRASDHDPLLL
                     QLSFGKDKPAAPSDQPKKTPAPAATTQASKAGRAQLLPKTGDKTALMVSILGLTAVFS
                     SFSLFRKCQERK"
     gene            complement(4439..4576)
                     /locus_tag="TV191_000657"
     CDS             complement(4439..4576)
                     /locus_tag="TV191_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003585727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL1507194.1"
                     /translation="MHQNPTERSVLLSTYEALQLMLAFGSFLLTLISLVVAIVILNNK
                     K"
     regulatory      4820..4938
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            4936..5442
                     /locus_tag="TV191_000658"
     CDS             4936..5442
                     /locus_tag="TV191_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEL1507195.1"
                     /translation="MTSFTVRDYVYIALVAALYVVLTITPPLNAISYGMYQFRVAEMM
                     NFLAFYHKKYIIAVTLGCMIANFYSFGLIDVLVGGGSTLIFVSLGVALFKQYQEEYLL
                     NGLLNKAFVYFSLFFATSMITVAIELYFFGAPFFLTWFTTAVGEFASLIIGSMIIDRL
                     SKRINLRQ"
     gene            5539..7497
                     /gene="ligA"
                     /locus_tag="TV191_000659"
     CDS             5539..7497
                     /gene="ligA"
                     /locus_tag="TV191_000659"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEL1507196.1"
                     /translation="MKKRIRELTDLLNQYRQEYYTNDAPSVSDSEYDKLYRELVELEQ
                     TYPAYILKDSPTQLVGSTILTGFQKYQHQYPLFSLQDAFSREELNAFDQRIKSAFPEA
                     EYLAELKIDGLSISLVYEAGVLKVGATRGDGTIGENITENIKNIKDIPKRLSQALDVT
                     IRGEAYMSRQAFKTINEERQENGEPEFANPRNAAAGTLRQLDTRIVAKRQLATFLYQE
                     VGLETADSQQKTLERLADLGFSVNSHYLLSSSMNDIWDFIQSIEASREELPYEIDGVV
                     VKVNQLAIQEELGFTVKAPRWAIAYKFPAEEKEAEIVSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRIGDTVVVYKAGDIIPAVLRVVEAKRRDQAPMPIP
                     TACPSCQSQLVHFEDEVALRCINPLCPSLVQRSLEHFASRQAMNIAGLGPAVVEKLYS
                     AGLVHDVADIYRLSLEDLLTLDGIKEKSAEKLLAAIEQSKANSAEKLLFGLGIRHIGA
                     KASRLILEAYGDLEALLAVTAEELAQIDGLGLVIGQSLVQYFQQEQAAQLLAELKSAG
                     VNLAYLGQRPDQQAALFGLTVVLTGKLEKLNRTQAMEKLEQLGAKVTGSVSKKTDLVV
                     AGSEAGSKLAKAQQLGIRIEDEDWLLNL"
     gene            7510..8532
                     /locus_tag="TV191_000660"
     CDS             7510..8532
                     /locus_tag="TV191_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEL1507197.1"
                     /translation="MKKQMRARLIYNPTSGQEIMKKNVAEVLDILEGFGYETSAFQTT
                     AAKHSALKEARRAAKAGFDLLIAAGGDGTINEVVNGIAPLEKRPKMAIIPAGTTNDFA
                     RALKVPRGNPVEAAKLIGKNQTIRMDIGRAKKDTYFINISAAGSLTELTYSVPSQLKT
                     MFGYLAYLAKGVELLPRVSNVPVKITHDHGIFEGEVSMIFAAITNSVGGFEKIAPDAK
                     LDDGMFTLILIKTANLFEIVHLLRLIIDGGKHVTDRRVEYIKTSKITIEPQSDKRMMI
                     NLDGEYGGDAPITLENLKNHITFFANTDLISDDALVLDQEELEIEEMVKKFAHEVEDL
                     EQGLEE"
     gene            8541..10841
                     /gene="pulA"
                     /locus_tag="TV191_000661"
     CDS             8541..10841
                     /gene="pulA"
                     /locus_tag="TV191_000661"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEL1507198.1"
                     /translation="MDNAVIVHYHSCKGHYFQLSLWQWRDGKLGKDAYFSRFDSFGAV
                     AYLTYPAPYFLSHAYVIVKDQFWQHQTVDFRIERDYGVPKTEVWLVDGDPTVYYSRQA
                     AVASRHDGRCDVHAFDMAVNSQAFDKRWGFSGWLGFRYQPEETSFRLWAPTAEKVELI
                     LYASTDERASVAKVLPMQRGQQYSPDHHAENTCGVWDISLRGDYNYHAYCYRVYYRRR
                     TFRDTRDPYAIATTANGKRSIVIAPEHLRPQGFSVKQGKEATWRLDNPNQAVIYEMHV
                     RDFSKSETSGVSLANRGKFKGLIETGTRNAFGDSTCFDYVKSLGITHIQLQPVFDHHQ
                     FFDENGDYAYNWGYDPENYNVPAASFTSNPHEPATRILELKEVIQAYHDAGINVIMDV
                     VYNHTYSSRESAFQLTVPDYYYRMNPNGSFQNGSGCGNETASEKEMYRKYMLDSILYW
                     TNEFNIDGFRFDLMGLHDIDTMNLIRQELDKIDPRILVFGEGWDMGVGLAAEQKAKKG
                     NASQMPGIGFINDDQRNAVKGAEVYGSLEKGFVSGAPTEGLVAKSILGSDELVSYCTP
                     SQVINYVEAHDNYNLNDLLWVLNPEDSKQDHVKRVQLASAMTILMQGIYFMQLGQEFL
                     RTKLYPTGQDKELTQADRERAMNSYNAPDNVNQVDWRQVSLERETVAIMKKLIYLKTK
                     TALFSYPSFEQIRQHVYIEHAGENTGFISFTVEDERKYRLIFSSFRNRLQSSANHVII
                     ETNDKRFQDSESMLDELTAMILDITQ"
     gene            10988..12867
                     /gene="glgB"
                     /locus_tag="TV191_000662"
                     /pseudo
     CDS             10988..12867
                     /gene="glgB"
                     /locus_tag="TV191_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004234331.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
     gene            12934..14073
                     /locus_tag="TV191_000663"
     CDS             12934..14073
                     /locus_tag="TV191_000663"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019785022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEL1507199.1"
                     /translation="MKNGMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVITQYQPLALNNHIGNGSSWGLDGINSGATILQPYSATEGNRWFQGT
                     SHAIYQNIDYIDSINPEYVLILSGDHIYKMDYDDMLQTHKANMASLTVAVIDVPLKEA
                     SRFGIMNTDTNDRIVEFEEKPANPKSTKASMGIYIFNWQRLRTMLVDAEKNNIDMSDF
                     GQHVIPSYLESGERVYTYNFKGYWKDVGTIESLWEANMEYIGEENALDSRDRSWKIYS
                     KNHIAPPNFITEDAEVKDSLVVDGSFISGKVNHSILSTNVQVRKGAEVKDSFIMSDVI
                     IGEGARITRAIIGEGAVIGDHVIIDGSKDVQVVGYNEVVGVPNED"
     gene            14063..15196
                     /gene="glgD"
                     /locus_tag="TV191_000664"
     CDS             14063..15196
                     /gene="glgD"
                     /locus_tag="TV191_000664"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEL1507200.1"
                     /translation="MKIDKYSAILGSSIGFAEMKGLTDTRPLANLPFDGKYRLIDFQL
                     SNLANAGVRSIYGIFRGQNIRSVFDHIRSGREWGLNSLLSHYFLGFYNTKEDSKEADK
                     DYYQQILTYLKRSGSDQTIYMSCDILCNIELGQVIHLHNANHRNITVVYKKMPTKAIS
                     KANDILDIDETDTVVDRRSLSEGQEVEKMSAGIYIVNTPWLIEQMEKEAEKENPQKLR
                     FLLRDLIVSEGALGFEYTGYLANIHSVKSYFDANMDMLDPHKFYSLLYANQKVYTRVK
                     NEESTYFDAASEVNNAQFASGSIVKGYVEHSIVSRNCRITSQARVTNSILLPKAVIGE
                     GAVIDYAIIDKSVRVAPGVTIRGSAEEPIVVAKGTEVVEDMIK"
     gene            15193..16623
                     /gene="glgA"
                     /locus_tag="TV191_000665"
     CDS             15193..16623
                     /gene="glgA"
                     /locus_tag="TV191_000665"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEL1507201.1"
                     /translation="MKIMFVAAEGAPFAKTGGLGDVIGALPKSLVKNGHEVSVILPYY
                     DVVDQAFGQQVEDVLYFYTQVGWRRQYVGIKKLVKDKVTFYFIDNQGYFFRGRIYGDW
                     DDGERFAYFQLAAIEAMEKIGVIPDILHVHDYHTAMIPFLLKEKYHWIQAYQAIRTVF
                     TIHNIAFQGQFDPGMLGDLFDVGIERYEDGTLRWHDCLNWMKAAVLYADRVTTVSPSY
                     AHEIQTPAFGQGLDQVMRMEAGKLSGIVNGIDTDLFNPARDPHLPASFSAEDLSGKAA
                     TKQALQERLGLPVRADVPLIGMVSRLTDQKGFQLVLEELPHILQQDVQLVLLGTGDPD
                     YEAAFSWFAKAYPEKLSANITFDLPLAQQIYGACDLFLMPSAFEPCGLSQMMAMRYGA
                     IPIVHEIGGLKDTVASYNAYEKTGTGFGFDQFSGFWLTQTLLFALDIYHNHKEDWQTI
                     QQHAMTKDFSWDTASLAYLDLYKSLL"
     gene            16642..19038
                     /locus_tag="TV191_000666"
     CDS             16642..19038
                     /locus_tag="TV191_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004234325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HEL1507202.1"
                     /translation="MHVTKEQFIRDFKDTLHEEQLIKVPAATAAELFTSLAKLIRKYY
                     TDTWIERNRSLTEQQQKIAYYFSIEFLPGRMLETNLLNLGILDTVKEAFADLGIDFQA
                     VKHAEHDMALGNGGLGRLAAAFMDSLATTGYPGFGNGLRYRYGLFKQRIVNGYQVELP
                     DSWFGSIGNVWEIRKDHDIVDVKLFGNVYLKANQDGKLAPIYEGAQVLRAVPYDVPQI
                     GFENDVINNLRLWDVEIPEEHELDYPTIESRRAVKDITAILYPDDSSYEGKKLRLIQE
                     YFMTSAGIQTIIKSYLKQGLPLTELHQKVSVHINDTHPAVAPAELMRLLIDDYGLEWV
                     DAWATTVKTMSYTNHTILSEALEKWDAELFKTVLPRVYQIILEIDHRFVAEMAQKGID
                     PQIIENTRIVKDNQIYMANLAIIGGYSVNGVAKLHTELLKTDTLKDFYALYPEKFNNK
                     TNGIVQRRWTQIAAPELSAAIDRTIGKGWRKDIHQLRQLSQFTEDPAVLNDFYQVKQA
                     AKQRLARYILEKTGLEVSTEAIFDVQVKRLHAYKRQLLNVLHIMKLYLDLKANPDLDM
                     VPRVFIFGAKAAPGYHFAKSVIKIINELANLINHDTSLKGKLKVVFLENYNVSLAELI
                     IPAADISEQISLASKEASGTSNMKFMMTGAITLATLDGANIEIKDEVGEENIVIFGMD
                     KDQVYDHYAKHDYYSRGLYESDPQIKAVVDAFVNGTIPNSQHEGMEIYDALITHNDEY
                     FLLEDFSSYVKAQAKIDRLYRQKDRWSKMSLINIAHSDKFTSDDTITQYAKDIWQLKR
                     "
     gene            19380..19577
                     /locus_tag="TV191_000667"
     CDS             19380..19577
                     /locus_tag="TV191_000667"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEL1507203.1"
                     /translation="MNPIFALALACFGVSLAEGFLMANLFKSASRQPEIIGQLRSLMI
                     LGVAFIEGTFFVTLVMAFILK"
     gene            19611..20327
                     /gene="atpB"
                     /locus_tag="TV191_000668"
     CDS             19611..20327
                     /gene="atpB"
                     /locus_tag="TV191_000668"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEL1507204.1"
                     /translation="MEEAKVPMVELGPITFNLTLLAVCIVTILLIFGFVFWASRQMTL
                     KPKGKQTALEYLISFVNGIGEEHLDSHLQKSYSLLLFTIFLFVAVANNLGLFTKLETT
                     SGYNLWTSPTANLAFDLALSLFVTLLVHIEGIRRRGFGAYLKRFATPWPMTPMNLLEE
                     FTNFLSLAIRLFGNIFAGEVVTGLIVQLANYRLYWWPIAFLVNIAWTAFSIFISCIQA
                     FVFTKLTATYLGKKVNESEE"
     gene            20345..20839
                     /gene="atpF"
                     /locus_tag="TV191_000669"
     CDS             20345..20839
                     /gene="atpF"
                     /locus_tag="TV191_000669"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEL1507205.1"
                     /translation="MSVTIGELIGNFILVTGSVIVLLLLIKAFAWGAIEAVLQARSQQ
                     ISQDIDQAEQARLNAQQLEKEGQANLEASRSEASQIVEAAKETGKAQETRIVAEATEE
                     ADRLKAAALTDIEHSKSEAISAVKTEMSDLTVLLAEKIMGANLDKAAQSQLIDRYLDD
                     LGEA"
     gene            20839..21375
                     /locus_tag="TV191_000670"
     CDS             20839..21375
                     /locus_tag="TV191_000670"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEL1507206.1"
                     /translation="MTKKEQALIEQYAKSLVQVCQERDTLEALQADVLAILEVFKATN
                     LAKTLSSLAVPRAKRLELVRQLQGDNIVYLNNLLEVMLQNEREAYLYQVLLRVLSELA
                     SVSNQYDVTVTSAVPLSEEQKQRVRTVVSKRLAVKTGRLIEKVDPSLIGGFMISVNNK
                     VIDTSIRRQLQAFKMNLK"
     gene            21391..22896
                     /locus_tag="TV191_000671"
     CDS             21391..22896
                     /locus_tag="TV191_000671"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEL1507207.1"
                     /translation="MAINAQEISALIKKQIENFQPNFDVTETGVVTYIGDGIARARGL
                     DNAMSGELLEFSNGTFGMAQNLESNDVGIIILGDFSTIREGDEVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPVDGLGDIETTGFRPVETPAPGVMQRKSVFESLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTSVAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLRRYGAL
                     DYTIVVTASASQPSPLLFIAPYAGVAMAEEFMYNGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERSAKVSDDLGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLQEDLFNSGIRPAIDAGSSVSRVGGSAQIKAMKRVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQPLHKPLPVEKQVVILYALTHGFLDDVPV
                     DDILAFEEALYDYFDAHYDHLFETIRTTKDLPQEAELDVAIQAFKAQSNFK"
     gene            22914..23789
                     /locus_tag="TV191_000672"
     CDS             22914..23789
                     /locus_tag="TV191_000672"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEL1507208.1"
                     /translation="MAGSLSEIKAKIISTEKTSKITSAMRMVSSAKLVKSEQAARDFQ
                     IYASKIRQITTDLLKSDLTTGSDNPMLVSRPVKKTGYIVITSDKGLVGGYNSKILKSI
                     MDMIQEYHAAGDYEIISIGSIGSDFFKARGMNVAFELRGLADQPSFDQVGRIISQSVG
                     MFVNEIFDELYVCYNHHVNSLTSQVRVQRMLPISDLVAEEAAEEGVTGFELEPNRHVI
                     LEQLLPQFTESLIYGAIIDAKTAEHAAGMTAMQTATDNAKHVINDLTIQYNRARQAAI
                     TQEITEIVAGANALE"
     gene            23957..25363
                     /gene="atpD"
                     /locus_tag="TV191_000673"
     CDS             23957..25363
                     /gene="atpD"
                     /locus_tag="TV191_000673"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEL1507209.1"
                     /translation="MSSGKIAQVVGPVVDVVFASGDKLPEINNALIVYKDGDKKQKIV
                     LEVALELGDGMVRTIAMESTDGLTRGLEVLDTGRAISVPVGKETLGRVFNVLGETIDL
                     EAPFADDVNREPIHKKAPAFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLTQ
                     MGIYPAVDPLASSSRALSPEIVGEEHYAVATEVQRVLQRYRELQDIIAILGMDELSEE
                     EKTLVGRARRIQFFLSQNFNVAEQFTGLPGSYVPVAETVRGFKEILEGKHDHLPEDAF
                     RAVGPIEDVIEKAKKMGF"
     gene            25376..25792
                     /locus_tag="TV191_000674"
     CDS             25376..25792
                     /locus_tag="TV191_000674"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEL1507210.1"
                     /translation="MTQMTVQVVTPDGIKYDHHAKFISVTTPDGEMGILPNHINVIAP
                     LQVHEMKIRRVSEDDRVDWVAINGGIIEIKDNVVTIVADSAERDRDIDVSRAERAKLR
                     AERDIAEAETTHDIDEVRRAKVALRRALNRINVSKK"
BASE COUNT         7227 a         5034 c         6200 g         7438 t
ORIGIN      
        1 atttgatttt agattaaaag gtttacaagc tttgatttta aagcattcta ggactgtcct
       61 agaatgcttt tagttttgat aagcacaatc cgctgttgac tgtataaacc gtatatgata
      121 caaaataaga gcttgtagca gtgaagccac taactctagt gctgtgggct caaccttgat
      181 tgatgaatcc cttgctttta atgcgtttat gaagcagtgg cgtatcagtc tagctcgttg
      241 tggaaagcaa ttaactagag aagaattact atcctcaatc aatatgctga cagccgcagg
      301 gatttgtgag tttgatttgc tgtggcagcg tcttgctcct aaggggtgtc agcgtcccaa
      361 atggagccat cagctggaga ggctctttgc ggatacaaag ccttgtctac aggtcttgtc
      421 tgagacttat cagcttggga ttattgctaa tcaggcaaag ggtctaaaag agcgcttaga
      481 gaggtttggg attagtcatt attttgccct tatgatatct tcttctgatg tggggctaca
      541 aaagcctgat cttgctctgt ttcgctatgc acttgatcaa gcaggcgtat tagcgcgtga
      601 tgctgtttat attggggatc gtgttgacaa tgatattatt cctgctaagg cattgggaat
      661 gagagctgtc aggattcatc aagggcttgc tgcgtccagt ccagatgata ggctttatcc
      721 tagtgatgtc catattagca aacttagtga cctgttagaa tgcttttaac cagtctttag
      781 cttgaactag cttttctttg tggtctttct gggtgaatgg cagcaagctt tggagtcatg
      841 ttatggctag accttggatc taagggcgct gagcgtctca tatgatgagg ccgatcaagt
      901 agtctccttg acaagtagat tattgtttgg tgcttatagg tggctttagg tgatgactgg
      961 ttttgcctca actaaggctc gctattgcta tctggggtat cttctgactt ttttaatgtg
     1021 ctcttatctg gttggattag acctgctcct tgcttgagga aagctgtttt taacgctgat
     1081 gagtctggga aatggtgaga ttggtgttgg cttttactag tttttttgcg tttacttggg
     1141 ctaactttat atgagaaaaa aagaaaaata tttattttat ctgttatttt tgttacaata
     1201 agcgtgtaaa ctaagatgca ttaaaaagga gtttttatgt cgaataagaa attttttact
     1261 tatgcttcat tattggcatt aatcgctgtt cctactgtgg ttgaagaggt gactgcacag
     1321 ccttcagctc agcttgttta tgcagatgag ctaaggctat caccaagtac cgactcatct
     1381 ccagtaacaa agaccgatga ggctgatcag ccagttgctc aatctgtttc tgcgacagaa
     1441 ccagtagagg ctcttgttat tgcggataaa gaaagcgctt taaatcctgc tgttctagct
     1501 gatgccgatg gaagtcagcc gattgcagtg gttagagctg gtcaagaggg tcagccttat
     1561 accgttactg gcaaaatcat cagtgctgtt aatggctggg gtggtcatgg cttttatatc
     1621 caggacagtc agggatcagg tctttacatt tatccaggaa gtgctttggg gtacgtgact
     1681 ggtgatgtgg tgcagctgac aggaacactg actacttaca agggtgagct tcagcttaaa
     1741 acgattacaa agcatcataa gattaatggc gaattaccaa cacctattgc tgaggtaacc
     1801 attccggagc tagaaaaagc aagcccgtct accctggtga agctttcaaa tgtgactgtt
     1861 ggagacattt catcagataa gcacgaaacc tcctctttta aggtcagcga tacagctggc
     1921 aatagtgttg cggtgcgtct tgataatcgt acaggtgtta agacctctga cttactctct
     1981 aaaattggca agggtgatgt gattaatctg acagctattc actcaacctt tgatgggaag
     2041 ctccagctca agccctttag ccttgagcaa tttgaggtag taaagaaggt tgttcgagaa
     2101 gaagaggtga ctcctcttgg tcgagtggtt aaaatcggcc aaattcaagg tgccagccac
     2161 acctcaccgc tcttgaatca agctgtaaca gtaaaagagg tggtggtgac ctatcttgat
     2221 gatgcaactc atttctatgt gcaagatatt aatggtgaca acgataaggc gacctcagac
     2281 ggtattcgtg tctttgctca aaatgctcag gtgcaggctg gtgatgtgct gaccatttcc
     2341 ggaacagtgg aggagttctt tggcaaaggc tacgatgacc gtaagcagac ggatctgacc
     2401 attacgcaaa tcaaggcatc taaggtcact aaaacaggga ctgctcaggt accagctccg
     2461 cttgtgctag gtaaggatcg tgttgctcca gctaatatca ttgataatga tggctttagt
     2521 gtttttgatc cagaagagga cgctattgat ttttgggaat ccttggaggg aatgcttgtt
     2581 gccgttgata atgccaagat tttagggccg atgtctcata aggaaattta tgtgttacca
     2641 gggtcatcaa ctcgagtgct gactaactca ggtggtattt tacttcctga gacaggctat
     2701 aatacagacc tgattcctgt tctctttaaa aaaggaaagc aaaccatcaa agctggtgat
     2761 tcctatcagg gacgacttgc aggtccggta tcatatagct atggtaatta taaggtgttt
     2821 gtcgatgaca gcagtcgtat gccagtcttg gttgatggtc agctgaagcc tgaaaagaca
     2881 cacatcaaga aggaccttag caagctaagc attgcctcat acaacattga aaacttctca
     2941 gcaaacccat catcaacaaa agacgagaag gtaaggcgca ttgcagaatc cttcatctat
     3001 gacctaaatg ctcctgatat tattggtctc atcgaggttc aggacaataa tggacctact
     3061 gatgatggca caacagatgc aacacaaagc gctcagcgct tgattgatgc catcaaggcc
     3121 ttaggtggac cagcttatca atatgtggat attgctccgg aaaataacgc tgatggtggg
     3181 cagccgggca gtaatattcg gacaggcttc ctgtatcagc caggacgtgt cagcctttct
     3241 gataagccta gaggtggtgt taatgatgcg gtgaaatggg taaatggtga gctaagcttg
     3301 agtgttggac gtattgaccc aacaaatcct gcttggaata gtgttagaaa atcattggct
     3361 gctgagttta ttttccaagg ccacaaggtt gtggtggttg ccaatcattt gaattccaaa
     3421 cgaggcgaca attcattata tggacgtgtt cagccggtaa cctttaaatc agaggaaaga
     3481 cgtcatgtct tagcaaggct tttgagccaa tttactaagg aaggtgctag tcagcaggct
     3541 aatatcgtta tgttgggtga ctttaacgat tatgagttta cgaagaccat taagctgatt
     3601 gaagaaggag atatggcaaa tttggtgagc aggcatgagc tttctgaccg ttattcttac
     3661 ttctatagag gaaataacca aacgcttgat aacatgcttg tttcacgcaa tttgcttggt
     3721 cgctacgagt ttgacatggt tcatgtgaat tcaccattta tggaagcgca tggacgtgct
     3781 tctgatcatg atccgttgct tcttcagctc tcctttggaa aagacaagcc agcagcacca
     3841 tcagatcagc caaagaaaac accagcacca gctgcgacaa ctcaagcctc taaggcagga
     3901 cgtgcacagc tattgccaaa aacaggtgat aagacagcgc ttatggtaag tattttaggc
     3961 ttaacagctg tctttagctc ctttagcctg tttaggaaat gtcaggaaag gaagtaaagg
     4021 atttctttgg ggtaggccag cagctgagcg gctactgcgt tttgtctgct ggtgctatat
     4081 aggtggttga agcgagcgaa gagaggtatg cttcctagga tcatagcaca atatcttatg
     4141 cttataaacg aacacaatgc tccttatgag cattcaaaac ctatactcaa aaggaatata
     4201 acagctgagt taagagggat tgcttttgac agattgtggt aaaaaaaggg atcttgagga
     4261 attggctagt gatctagctg ccaaaatgcg atgtcttgtt tgactatttt tccctattgg
     4321 gatataatga caatagaaaa agggtagttg tttgcgcaac taccctgtgc agaaccgttt
     4381 aagacggtgg cagaatgaaa gttaaaaaat aatcgtcgac ctaccaaagt tcagacggtt
     4441 attttttatt gtttaatatg acgattgcaa cgactaagct gattaaggta agtaagaaac
     4501 taccaaaagc cagcatgagt tgaagggcct cgtaagtaga caataaaacg ctcctttcag
     4561 ttggattttg atgcattgcc cataggcatc accacctttc agaaatcaga gccaccgtct
     4621 tagcttttct gtaaagaaca ttatatcata atcacatgag aaagccgtta gattttaaac
     4681 tgatcaggcg gctttttggt gttttgctgt cttttagtgg aatcgcctaa gctttgctgt
     4741 atagtatggg attttatgct ttttgtaagg gcttaggctg ctatggcagg gtccatgtcc
     4801 tttgtcaata gcttagtttt atggtacaat gtaggcgttg cctagcaacc cttggtgctt
     4861 agttcccttt caccaagcat attacaaacg tggcggagct gtttatgctc tagtctgacg
     4921 tcaaaggaga aacacatgac aagttttact gttcgtgact atgtttacat tgctctagtg
     4981 gctgcccttt atgtggtttt gacaatcact ccacctttga atgctatttc ctatggcatg
     5041 tatcaatttc gggttgccga gatgatgaat tttttggctt tttaccataa aaagtatatc
     5101 attgcggtga ccttgggctg tatgattgct aatttttata gctttggctt gattgatgtt
     5161 ttggtgggtg gaggctcaac gctcattttt gttagcttag gtgtcgcttt atttaagcaa
     5221 taccaagagg aatatctctt aaatggcttg ctgaataagg cctttgttta tttctcacta
     5281 ttttttgcga cttctatgat caccgttgcg attgagcttt acttctttgg agcaccattt
     5341 ttcctaactt ggtttaccac tgctgtaggg gaatttgctt cacttatcat tggctctatg
     5401 atcattgatc gcttatcaaa acgcattaat ttacgacaat aatagtaaca tgtagccttc
     5461 cgtttttggg aggcttttta tgattttctt ctagctaggc aatagcttat ttgctatgtt
     5521 ttgtgataaa ataagactat gaaaaaacgc ataagagaat tgactgatct gttaaatcaa
     5581 taccgtcagg agtattacac caatgacgct ccttctgtat ctgatagtga gtatgataag
     5641 ctttatcgtg agcttgtaga gctggagcag acctatccag cctatatcct aaaggacagc
     5701 cccacacagc tggtgggcag tacgattttg acaggatttc agaaatatca gcaccagtat
     5761 ccgctcttta gtttgcagga tgctttttca cgtgaagagc ttaacgcctt tgatcagcgg
     5821 atcaaatcag cctttcctga ggctgaatac cttgctgagc taaaaattga tggcttgtcc
     5881 atttcgctgg tttatgaggc tggtgttcta aaggttggag cgacacgtgg cgatgggact
     5941 attggcgaga atatcactga aaacattaag aatattaagg atattcccaa acggctaagt
     6001 caagcacttg atgtgacgat acggggggag gcctatatgt cgcgtcaggc ctttaagacg
     6061 atcaatgaag agcgtcagga aaatggtgag ccagaatttg ccaatccaag aaatgcagcg
     6121 gcaggaacct tgaggcagct ggatactagg attgttgcca agcgacagct agcaaccttt
     6181 ttgtatcagg aggtaggcct agaaactgct gatagccagc aaaagacctt ggagcgcttg
     6241 gccgatttag gcttttcggt caatagccac tatctgctgt cctcatcgat gaatgacatt
     6301 tgggacttta tccagagcat tgaagctagt agagaagagc taccttatga gattgatggt
     6361 gtggtggtca aggttaatca gttggcgatc caagaggaac ttggctttac cgtcaaggca
     6421 ccacgctggg ctattgctta taagtttcca gcagaagaaa aggaagctga gattgtatct
     6481 gtggattgga cggttggccg aacaggtgtg gtcacaccaa cagctaattt gacccctgtg
     6541 cagctggcag gcaccactgt cagtcgagcg accttgcata atgttgatta tatcgcagaa
     6601 aaggatattc gcattgggga tacggtggtg gtgtataagg ctggagatat tattccagct
     6661 gttttgcggg tggttgaggc taagcgtagg gatcaggctc caatgcccat tcctacagcc
     6721 tgtccttcct gccagagtca gctggtgcat tttgaggacg aggtagcttt gcgttgcatt
     6781 aaccccttgt gtccgagctt ggttcaacgg agcttggagc attttgccag tcgtcaggcg
     6841 atgaatatcg ctggtcttgg tccagcggtt gttgaaaagc tttattctgc tggcctggtg
     6901 catgatgtgg cagatattta ccgactaagc ttggaggatt tgctgacgct agatggtatc
     6961 aaggaaaagt cggctgaaaa gctcttggca gctattgaac aatcaaaggc aaactcagct
     7021 gaaaagctct tgtttggact tggtattcgt catattggcg caaaggctag tcgtctgata
     7081 ttagaggctt acggtgattt agaggcgctg ttagctgtaa ccgctgaaga gctcgctcag
     7141 attgacgggc ttggtctagt gatcggacaa tccctggtgc agtattttca gcaagagcaa
     7201 gccgctcagc tgctagctga attaaaatca gctggggtta atctggctta tttaggccaa
     7261 aggcctgatc aacaggctgc gctgtttggt ttaacggtgg tattgacagg aaaattagaa
     7321 aagctaaacc gtacccaagc catggaaaag ctagagcagc ttggtgctaa ggtaacagga
     7381 agcgtttcta aaaaaacaga tttagtggtt gctggcagcg aggcaggctc taagctggct
     7441 aaggcccagc agctgggtat cagaattgaa gatgaggatt ggttgctcaa tctttagtga
     7501 ggtaataaca tgaaaaaaca aatgagggct cgtctgattt acaatccaac ctctggtcaa
     7561 gaaatcatga aaaaaaacgt tgcagaggtg ctggatattt tggaaggctt tggctatgaa
     7621 acctctgcct ttcaaacgac agcagctaag cactcagcct taaaggaagc aagaagggca
     7681 gctaaagcag gctttgacct cttgattgct gctggtggag atggtacgat caacgaagta
     7741 gtcaatggca ttgctcccct agagaaaaga cctaagatgg cgattattcc agcaggaacc
     7801 accaatgatt ttgctagggc cttaaaggta ccaagaggca atcccgttga ggccgctaag
     7861 ctgattggta aaaatcaaac catccgcatg gatataggac gtgctaaaaa ggatacttat
     7921 tttatcaaca tttcagccgc aggaagcctg acagagctga cctatagtgt ccctagtcag
     7981 ctcaaaacca tgtttggcta cctggcttat ctggctaagg gagtggagct cttgcctcga
     8041 gtgagtaatg ttccggtgaa aatcacgcat gatcatggca tttttgaggg agaggtatca
     8101 atgatttttg cagccatcac taattctgtt ggtggctttg aaaagattgc cccagatgct
     8161 aagctagatg atggcatgtt tacccttatt ttgattaaaa cagccaacct gtttgaaatt
     8221 gtgcacctgc tgcggttgat cattgacggt ggtaagcatg ttacggatcg ccgcgtcgaa
     8281 tacattaaaa ccagtaaaat caccattgag ccccaatcag ataagcgcat gatgattaat
     8341 ttagatggtg aatatggtgg tgatgcgcca attaccctag aaaacttaaa aaatcacatc
     8401 accttttttg caaatactga tttgatttca gatgatgccc ttgtcctaga ccaagaggag
     8461 ctggaaatcg aagaaatggt caagaaattt gcgcatgagg tagaggattt agagcaggga
     8521 ttggaggaat agggctagtt atggataatg cagttattgt tcattatcat agttgcaagg
     8581 gacattattt tcaattaagt ctatggcaat ggcgagatgg taagctgggc aaggacgctt
     8641 atttttcgag gtttgacagc tttggagcag ttgcttatct cacttatcca gcaccttatt
     8701 ttttgagtca tgcttatgtg attgtaaagg atcagttttg gcagcatcaa accgttgatt
     8761 ttcggattga gcgtgattat ggggttccaa agactgaggt gtggcttgtt gatggtgatc
     8821 ctacggttta ttattcgaga caggctgctg tggctagtcg acatgatggt agatgtgatg
     8881 tgcatgcctt tgatatggct gtcaatagtc aggcctttga caagcgctgg ggctttagtg
     8941 gctggctagg ctttcgctat cagcctgagg agacgtcttt tcgtttgtgg gctccaacag
     9001 cagaaaaggt tgagctcatt ctctatgctt cgactgatga gagagctagt gttgccaagg
     9061 ttttgcccat gcagcgtggg cagcagtact cgccagatca tcatgcagaa aacacatgtg
     9121 gtgtgtggga catcagccta agaggtgatt ataattacca tgcttattgc taccgggttt
     9181 attatcgcag gcgtaccttt agagacacta gggatcctta tgcgatcgca acgacagcaa
     9241 atggcaaaag gtcaattgtc attgcaccgg agcatttaag accgcagggc ttttcagtga
     9301 agcagggtaa ggaggctacc tggcgcttag acaatcctaa tcaggcggtg atctatgaaa
     9361 tgcatgttcg cgacttttca aaatcagaaa cctcgggcgt tagcttggct aatcgtggca
     9421 aatttaaggg gctgattgag acaggcacgc gcaatgcttt tggagattca acctgctttg
     9481 attatgtcaa gtcccttggc attacgcata ttcagctcca gccggtcttt gaccatcatc
     9541 aattctttga tgaaaatgga gattatgcct ataattgggg ctatgaccct gaaaattaca
     9601 atgttccagc agccagcttt accagtaatc cgcatgagcc agctacccgt atcctggaat
     9661 taaaggaggt cattcaggct tatcatgatg caggcatcaa tgtgatcatg gacgtggtgt
     9721 acaatcatac ctactcatca agagagtcag cctttcagct gacggttccg gattattatt
     9781 accgtatgaa tcctaatggc tcctttcaaa atggctctgg ctgtggcaat gaaacggcta
     9841 gtgaaaagga aatgtatcgc aaatacatgc ttgattcgat cctatattgg accaatgagt
     9901 ttaacattga tggcttcagg tttgatctga tgggcttaca cgatattgac accatgaatc
     9961 ttatccgaca agagctagat aagattgacc caaggatact tgtttttggt gagggctggg
    10021 atatgggagt tggtctggca gctgagcaga aggctaaaaa aggaaatgcc agccaaatgc
    10081 ctggaatcgg ctttattaat gatgatcagc gtaatgcagt taagggggca gaggtctatg
    10141 ggagcttaga gaagggcttt gtatcaggtg caccgacaga aggacttgta gccaagtcta
    10201 ttttgggcag tgatgagctg gtctcttatt gtacgcctag tcaggtgatc aattatgttg
    10261 aagctcatga caactataac ctcaatgatt tgctgtgggt tttgaatcca gaggacagca
    10321 agcaggatca tgtcaaacgg gttcagctag cttcagctat gacgattctc atgcaaggga
    10381 tttactttat gcagctgggt caggaatttt tacgaacaaa gctttaccca acaggtcagg
    10441 ataaggagct gacacaggca gaccgagaaa gggcgatgaa ttcctacaat gcacctgaca
    10501 atgtgaatca ggttgactgg agacaggtta gcttggagcg cgaaacggtt gctattatga
    10561 aaaaactaat ctatctgaaa actaaaacag ctttgttttc atacccatca tttgagcaaa
    10621 tcagacagca tgtttacatt gagcatgctg gtgaaaatac gggcttcatt agctttacag
    10681 tagaagatga aagaaagtat cgattgattt tctctagttt tagaaaccgc ttgcaatcat
    10741 ctgctaatca tgttataatt gaaacaaatg ataagcgctt tcaagatagt gagtccatgc
    10801 tagatgagct gacagcgatg atccttgaca tcacacaata gcctgagtgt tctcaggtta
    10861 tttttgtttg ttgtcaagga taaaagggct gtagttacag ttagcagaga cctattagga
    10921 ccttgcttat catatcgctt agcgccttga aaaagggttt aggagtaggg aaagaagagg
    10981 tgatgggatg gataatgact tagcgcttta tacctttggc acaggtgaga attttcacat
    11041 acaggattat ctaggtgttc atcggattaa caatgacaca ggcaccagct atgtctttag
    11101 ggtatgggcg cccaatgcag aggctgtcag cttgattgga gattttactg attggcagtc
    11161 caatccactt gagatgagcc gaaatgaggc tggcgtgtgg gaggttacca ctagcttgcc
    11221 gcaggaagga gatatttata agtattgggt taggcgccaa ggtggtcagc ttgttgaaaa
    11281 aattgatcca gtggcctttc tatttgaagc tagaccagga acgggtgcta ttgtcaaaac
    11341 ccttccagcc aaaaaatggc gtgatagctt atggatggga cggcgaaagc gttttggctt
    11401 taggcagcgt ccggttaata tctatgaggt tcatgcccat tcatggaaaa aagacgaaaa
    11461 cgcaaggccc tatgacttta gcaagctaaa agaagagctc attccctatc tcaagagcat
    11521 gcactacact catgttgagt ttatgccggt catggctcac cccttagata tgagctgggg
    11581 ctatcagctg atgggctact ttgcctttga gtcaaccttt ggaagcccag aagcctttca
    11641 ggattttgtt gaggcctgtc atcttaataa tattggtgtt ttgattgatt gggtgccggg
    11701 acattttaca caaaatgatg acgccttagc ttattttgac ggtacagcta cctatgaata
    11761 tcaggatcac catcgtgctc ataattatgg ctgggggccc taaattttga tttgggtaaa
    11821 actcaggtac agtccttttt gatttcaagt gccctttttt ggctggaggc ttatcatgtt
    11881 gacggcattc gagtagatgc tgttagcaat atgctttact tggattatga tcaaggccct
    11941 tggactccga atcaatacgg tggcaaccaa aaccttgagg ggatagcctt tcttcaaaaa
    12001 ttaaccacag ttatcaagga aaaacaccct gatgtgatga tgattgcaga ggaggcgacc
    12061 tcagctaccc caataaccag ccctgttgca gaagggggac taggctttga ttataagtgg
    12121 aatatgggct ggatgaatga tattcttagg ttttacgaag aggatcctta ttaccgaaaa
    12181 tacgatttca atctcttgac ctttagcttt atgtattgct ttaaggagca ttacatttta
    12241 cccttttctc acgatgaggt tgttcatggc aaaaaaagcc tcatgcataa aatgtggggg
    12301 gaccgctaca atcaatttgc aggcctaaga aatctttaca cctatcaaat ctgccaccca
    12361 ggcaagaagc tgctttttat gggatctgag tttggacagt ttttggaatg gaaatacgat
    12421 catcaattag agtggcaaaa tttagaggac gagctcaatg ccaaaatgca gcatttcaca
    12481 gccagcctaa atcagctata taaggaccat agcatgctgt ggcaaaatga tgaaacctat
    12541 gacggcattg atattattga tgcagacaat aaggacgaat cagtcttgtc gttttgtcgt
    12601 caaaacaata aaggagagct cctgctttgt gtctttaaca tgacacctgt tgaaagacca
    12661 ggctttacca taggtgtgcc gatagcaggt ctttatcaag aaattttcaa tacagagctt
    12721 gaggcctttg gaggtgtctg gaaggagcac aatcccttaa ccaacacagt agccaagaaa
    12781 tggaagactt atccgcagac cttgagcttt accctgcctg cactaggagc aagcatctgg
    12841 aaaatcaagc gtcgtcagaa gcaataagct attcattgct tacttagctg tttcaaccaa
    12901 aagaagtcac tacagtcatg aaaggataac gaaatgaaga atggaatgtt agccctcata
    12961 ttagcagggg gacaaggaac tcgcttagga aaattgacac agagcattgc aaagcctgct
    13021 gtgcaatttg gaggtcggta tcgtatcatt gattttgccc tatccaattg tgctaactca
    13081 gggattcata atgtgggggt tatcacccag taccagcctc ttgccttaaa taatcatatt
    13141 ggcaatggtt cgtcatgggg cttagatggt attaattctg gcgctacgat tttacagccc
    13201 tactctgcaa cagagggaaa tcgctggttt caaggaacta gccatgctat ctatcaaaat
    13261 attgattata ttgatagcat taaccctgaa tatgtgctga tcctgtctgg tgatcatatt
    13321 tacaaaatgg actatgatga catgcttcag acgcataagg ctaatatggc tagcttgact
    13381 gttgctgtga ttgatgttcc tctaaaggaa gccagtcgat ttggcattat gaacacagat
    13441 accaatgacc gcattgtcga atttgaagaa aagcctgcca atccaaaatc aaccaaggct
    13501 tcaatgggta tttatatctt taattggcag cgccttcgga ccatgctggt tgacgcagaa
    13561 aaaaacaaca ttgatatgtc tgactttggt cagcatgtga ttccgtctta ccttgagtct
    13621 ggcgagcgtg tctacaccta taactttaaa ggctactgga aggacgtcgg aacgattgag
    13681 tctctctggg aagccaatat ggaatacatc ggtgaggaaa atgccctaga cagtcgtgat
    13741 cgttcttgga agatttattc taaaaaccat atcgctccac caaactttat cacagaggac
    13801 gccgaggtca aggattctct ggtagtagat ggcagcttta tctctggtaa ggtcaaccat
    13861 tctatcttgt ctaccaatgt gcaggtaaga aagggagccg aggttaagga ttcctttatc
    13921 atgagcgatg ttatcattgg tgagggtgca aggattacac gagctattat tggtgagggt
    13981 gcagtcattg gtgatcatgt gatcattgat ggcagcaagg acgttcaagt cgtaggctat
    14041 aatgaagtag tgggggtacc aaatgaagat tgataaatat tctgccattc taggcagctc
    14101 aattggcttt gctgaaatga aggggctaac agacacaaga ccattagcca acctaccctt
    14161 tgatgggaaa taccggctca ttgattttca attgtccaac cttgccaatg caggtgtccg
    14221 tagcatctat ggtatttttc gtgggcaaaa tatccgctca gtgtttgatc atatcaggtc
    14281 aggtcgtgaa tgggggctta attccttact aagtcattat ttccttggct tttataacac
    14341 caaggaggat tctaaagagg ctgacaagga ctattatcag cagattttga cctatttaaa
    14401 gcgctcaggg tcagatcaga ccatttacat gagctgtgat attctctgca atattgagct
    14461 tgggcaggtt attcatctgc acaatgccaa ccatcgcaac attacggttg tctacaagaa
    14521 aatgccgacc aaggccatct ctaaggctaa cgatatttta gatattgacg agacagatac
    14581 tgttgttgac aggcgaagtc tgtctgaggg gcaggaggtt gaaaaaatgt cagcaggcat
    14641 ttacatcgtc aataccccat ggttaattga acagatggaa aaagaagccg aaaaagaaaa
    14701 ccctcaaaag ctacgcttcc tcttacgtga tttgattgtg tcagagggcg ctcttggctt
    14761 tgaatatact ggctatcttg ccaatattca ctctgttaaa tcttattttg atgccaatat
    14821 ggacatgctg gatccgcata agttttattc actattatat gctaatcaga aggtctacac
    14881 gcgtgtcaaa aatgaagagt caacctattt tgatgcggct tctgaggtga acaatgccca
    14941 atttgcttca ggaagcattg tcaagggcta tgtcgagcac tcaattgtct ctcgcaattg
    15001 tcgcattacc tcacaggcac gtgttacaaa tagtatttta ttgccaaagg cagtgattgg
    15061 tgagggtgct gtcattgatt atgctatcat tgataaatcc gtaagggttg caccaggtgt
    15121 tactattaga ggaagcgctg aggagccaat agttgttgcc aaggggactg aggttgttga
    15181 ggatatgata aaatgaagat aatgtttgtt gcagcagagg gagctccctt tgctaagaca
    15241 ggtggcctag gcgatgtcat tggggcattg cctaaatcac ttgttaaaaa tggtcatgag
    15301 gtgtctgtga tactgcctta ttatgacgtg gttgatcaag cctttggtca gcaggttgag
    15361 gacgtcttgt atttttatac gcaggttggc tggagacgcc aatacgtggg cattaaaaag
    15421 cttgtcaagg ataaggtgac cttttacttt attgacaatc aaggttattt ctttagaggc
    15481 aggatctatg gtgattggga cgacggtgag cgctttgcct atttccagct ggctgccata
    15541 gaagcaatgg agaaaatcgg ggttattcca gatattttgc atgtgcatga ttaccatacc
    15601 gctatgattc ctttcctatt gaaagaaaaa taccattgga ttcaggccta tcaagcgatt
    15661 cggacagttt ttaccattca taatatcgca tttcaagggc agtttgatcc tggcatgcta
    15721 ggcgatttgt ttgatgttgg tatagagcgc tacgaggatg gcaccctgcg ttggcatgat
    15781 tgcttgaatt ggatgaaagc agcagtccta tatgcagatc gggtaaccac tgtctcaccc
    15841 tcttatgcgc atgaaattca gacaccagcc tttggacaag gcttggatca agtcatgcga
    15901 atggaggcag gcaagctatc aggcattgtg aatggtattg acactgactt atttaaccca
    15961 gcaagggatc ctcatttgcc tgcttcattt tcagcagaag acctatcagg caaggcggct
    16021 actaaacagg ccttgcagga gcggttagga ttaccagtca gggcagatgt tccattgatt
    16081 ggtatggttt cgcgcttgac ggatcaaaag ggctttcagc ttgttcttga ggaattaccg
    16141 catatcttgc agcaggacgt tcagcttgtc ttgttaggaa caggtgaccc tgattatgag
    16201 gctgcctttt catggtttgc caaggcctat ccagaaaaac tgtctgctaa tattaccttt
    16261 gatctgccat tagctcagca gatttatggg gcctgtgatc tctttttaat gccaagtgct
    16321 tttgagccct gcggactttc gcaaatgatg gctatgagat atggcgcgat accgattgtc
    16381 catgagatcg gcggcttgaa ggatactgtt gcctcctaca atgcttatga aaagactgga
    16441 actggttttg gctttgatca gttttcagga ttttggttaa cgcagacgct cttgtttgcc
    16501 cttgatattt accataacca caaggaggat tggcagacta ttcaacaaca tgccatgacc
    16561 aaggattttt catgggatac agccagtctg gcctaccttg atttatataa aagcttacta
    16621 taacacagaa aaggaatggg aatgcacgtc acaaaagaac aatttattcg agattttaaa
    16681 gataccttac atgaggaaca attgatcaag gttcctgccg caacagctgc tgagcttttc
    16741 acctcattag caaagcttat ccgtaaatac tatacagata cttggattga aaggaatcgt
    16801 tccttaaccg aacagcagca aaaaattgcc tattattttt cgatcgaatt tttaccagga
    16861 agaatgctag aaacaaatct tcttaattta ggcattcttg atacagttaa agaagccttt
    16921 gctgacttgg gaattgattt tcaagcagtg aagcatgcag agcacgacat ggctctaggc
    16981 aatggaggtc taggacgttt ggcagctgcc tttatggatt cgctagcgac aacaggctat
    17041 ccaggctttg gaaatgggct gcgttatcgt tatgggctgt ttaagcaacg gattgtgaat
    17101 ggttatcagg tagaattacc agattcttgg tttggctcta ttggtaatgt ctgggagatc
    17161 agaaaggatc atgacattgt agacgtcaag ctctttggga atgtttacct aaaagccaat
    17221 caggacggta agctagcgcc aatctatgag ggagctcagg ttttgagagc tgttccctac
    17281 gatgttcctc agattggctt tgaaaatgat gtgattaaca atcttcgcct ctgggacgta
    17341 gaaatcccag aagaacatga gcttgattac ccaaccatcg agtcaagacg ggcagtcaag
    17401 gacattactg ccattttgta cccagacgac agcagctatg aaggcaaaaa gcttagattg
    17461 atccaagaat atttcatgac cagcgcaggc atccaaacca ttatcaaatc ctatttaaag
    17521 cagggcttgc cacttactga gcttcatcaa aaggtatctg ttcatatcaa tgatacccac
    17581 ccagcagtag ctccagcaga gcttatgcgg ctcttgattg acgactatgg cttagaatgg
    17641 gtagacgcct gggcgacaac cgtaaaaacc atgagctata ccaatcatac gattttgtca
    17701 gaagccttag aaaaatggga cgcagagctc tttaagactg tgctgccccg cgtttatcaa
    17761 atcattttag agattgatca tcgctttgtt gctgaaatgg cgcaaaaggg tattgatcct
    17821 cagatcattg aaaacactag aatcgttaag gacaaccaga tttatatggc taatcttgcc
    17881 attattggtg gctattcggt caatggcgtt gccaagctac atacagagtt gttaaagaca
    17941 gataccctta aggactttta tgccttgtat cctgaaaaat tcaacaacaa aaccaatggt
    18001 atcgtgcaaa gacgttggac acagattgct gcgccagagc tatcagcagc tattgaccgc
    18061 acgattggca aaggctggcg caaggatatt caccagcttc gacaattgag tcaatttaca
    18121 gaagatccag ctgtgctaaa tgatttttat caggtaaaac aagcagctaa gcagcgccta
    18181 gccaggtata tcctggaaaa aacaggtctt gaggtttcaa cagaggctat ttttgatgtg
    18241 caggtcaaac gcctacatgc ctacaagcgg cagctcctga acgtcctgca tattatgaag
    18301 ctttaccttg atttgaaggc taatccagat ttagatatgg tgcctagagt ctttattttc
    18361 ggcgcaaagg ctgcaccagg ctatcatttt gccaagtcgg tgatcaaaat catcaatgag
    18421 ctggctaatc tcattaacca tgataccagt ctcaaaggaa agctaaaggt tgtttttctt
    18481 gaaaattata acgtgagtct agcagagctc attatccctg cggcagatat ttcagagcag
    18541 atttcactgg cctccaagga agcctcagga acatcaaaca tgaaatttat gatgactggt
    18601 gctatcaccc tagcgaccct tgatggggca aacattgaaa tcaaagacga ggtcggagag
    18661 gaaaacattg tgatctttgg tatggataag gatcaggtct atgaccacta tgccaagcat
    18721 gattattatt caagaggcct atatgagagc gaccctcaga ttaaagcagt agtcgacgct
    18781 tttgtcaatg gcaccattcc aaatagtcaa cacgaaggta tggaaatcta tgatgcccta
    18841 atcacgcata atgatgaata cttcttgcta gaagactttt cttcctatgt aaaagcacag
    18901 gctaagattg atcggctcta ccgccaaaag gatagatggt caaaaatgtc gctcatcaac
    18961 attgcccatt ctgacaagtt tacatcagat gataccatca cccagtatgc caaggacatt
    19021 tggcagctaa aacgctaatc catcaaggaa gaaaaagcat tagttacctt agattgaaga
    19081 gagtgtcttt tgagaccatt ttcttcaatc ttttttgatt gcaaaagacc ttgggaatca
    19141 gatcagctgc ctgcctaata ctttggccta tcaaggtatt ttggaatttg ttaatctttt
    19201 tgttataata gtggtgtgaa gctatttttt aaatgaaaaa gccaacactt caagatggtg
    19261 ttaaagtaag gttagtatta gtctaagaaa gcgtaaccac attaaagaaa gctgttgaca
    19321 ttctcaattt taaggaatag aataacaaag taaaaaattt ttaaaaggag tattctatta
    19381 tgaatcctat tttcgcattg gctcttgcct gctttggtgt atcacttgcc gaaggctttt
    19441 tgatggctaa tctctttaaa tcagcgtcac gccaaccaga aattatcggt caattacgtt
    19501 ccttgatgat cctaggtgtt gcctttattg aaggtacctt cttcgttacc cttgttatgg
    19561 ccttcattct aaaataacag cctatttgat atagaaaagg agggtattaa atggaagaag
    19621 ctaaagtacc gatggtagag cttggtccaa taacctttaa tttgacccta cttgctgttt
    19681 gtattgttac tatcctactg atatttggct ttgttttttg ggcaagtcgt cagatgacat
    19741 taaaaccaaa aggcaagcaa actgcgttag aatatttaat cagctttgtt aatggtattg
    19801 gggaagagca tttggatagt catcttcaga agtcttattc gcttttactt tttaccattt
    19861 ttctttttgt ggcagttgcc aacaacttgg gcttatttac aaagctagaa acaaccagtg
    19921 gctacaacct atggacatcg ccaacagcta atttggcctt tgacctagcc ctatctctgt
    19981 ttgtgacgct tcttgttcat atcgaaggca ttagacgtcg tggttttggc gcttatttaa
    20041 aacgctttgc gacaccttgg ccaatgactc cgatgaacct attagaagaa tttaccaact
    20101 tcctatcact tgctatcagg ctgtttggta atatctttgc aggagaggtt gtgacaggct
    20161 tgattgttca gctggccaat tatcgcctgt attggtggcc aattgctttc cttgttaata
    20221 tagcatggac agccttttcc atatttattt cctgcataca agcctttgta tttacaaaat
    20281 taacagcaac gtatttagga aaaaaagtta atgaatcaga agaataagaa gggaggacaa
    20341 acgaatgtca gttacaattg gtgagctcat tgggaatttt attctggtaa caggctctgt
    20401 catcgtcttg ttgctcttga ttaaagcctt tgcttggggt gctatcgaag ctgttttaca
    20461 ggcacgctca cagcaaattt cacaggatat tgaccaagca gagcaggcgc gtctcaacgc
    20521 ccagcagctt gaaaaggaag gtcaagccaa tctagaagcc agcagatcag aggctagtca
    20581 gattgttgag gcagccaaag aaactggtaa agcacaggag acacgcattg tagcagaggc
    20641 tacagaagag gcagatcgcc taaaagcagc agcgttgaca gatatcgaac acagcaagtc
    20701 agaggctatt tcagccgtta agacagaaat gtcagatttg acagttttac tagcagaaaa
    20761 aattatggga gccaatcttg ataaggcggc tcaaagccag cttattgatc gctatcttga
    20821 tgatttagga gaggcttaat gaccaaaaaa gaacaagctc ttatcgagca atatgcaaaa
    20881 agtcttgtgc aggtctgtca ggagcgagac actcttgaag cactgcaggc tgatgtgctt
    20941 gccattttag aggtttttaa agctactaat cttgctaaga cattgtcaag cttagcggtt
    21001 ccacgtgcta aaaggcttga gctagtaagg cagcttcaag gagataatat cgtttatctg
    21061 aataacttgc tagaagttat gctgcaaaat gagcgtgaag cttatttata tcaagtgctt
    21121 ctaagggttt tatccgagct ggctagtgtc tcaaatcaat atgacgtgac agttacatca
    21181 gcagttcctt taagtgagga gcaaaagcag cgtgtgcgta cagtggtttc aaagagactt
    21241 gcagtaaaga caggtcgctt aatcgaaaag gtagatcctt ctttaattgg aggatttatg
    21301 attagcgtca ataataaggt aattgataca agcattcgtc gtcaattaca agcatttaaa
    21361 atgaatttaa aatagaaagt ggtgtgactt ttggcaatta atgcacaaga aattagcgct
    21421 ttaattaaaa agcaaattga gaacttccag ccaaatttcg atgtcacaga aactggagtt
    21481 gttacctata ttggtgatgg gattgcacgt gctcgtggct tagacaatgc gatgagtggc
    21541 gagcttcttg aattttcaaa tggtaccttc ggtatggctc aaaacctaga gtcaaacgat
    21601 gttggtatca ttattcttgg tgatttttca acgattcgtg agggtgatga agtcaaacgt
    21661 accggtaaaa ttatggaagt gccagtcggt gaagctctca ttggacgtgt ggtcaatcca
    21721 cttggtcagc ctgttgatgg cttaggtgac attgagacaa ctggctttag gcctgttgaa
    21781 actccagctc ctggtgttat gcagcgtaag tctgtttttg agtccttaca aaccggtcta
    21841 aaggctattg atgctttggt tccgatcggt cgtggccagc gcgagctgat tatcggtgac
    21901 cgtcagacag gtaagacgtc tgtagccatt gatgccatct tgaatcaaaa ggggcaggac
    21961 atgatttgta tctatgtcgc tattggtcaa aaggaatcaa cagttcggac acaggttgaa
    22021 accctacgtc gttatggtgc tttggattat accattgttg taacggcttc tgcttcacag
    22081 ccatcaccct tgctgtttat tgcaccttat gctggtgttg cgatggcaga agagtttatg
    22141 tacaatggca agcacgtttt gattgtttat gatgacctgt ctaagcaggc ggtagcttat
    22201 cgtgaattgt cgctcttgct tcgtcgccca ccaggtcgtg aggcctatcc aggagatgtt
    22261 ttctacctgc atagccgctt gcttgagcgc tcagctaagg tgtctgatga cttaggtggt
    22321 ggctcaatta cagccttacc atttattgag acgcaggctg gggatatctc tgcctacatt
    22381 gcgacaaacg tgatttcgat tacagatggt cagattttct tgcaagagga tctctttaac
    22441 tcaggaatcc gcccagctat tgatgctggc tcgtcagtat ctcgtgtcgg tggctctgca
    22501 cagatcaagg ctatgaaaag ggttgcaggg actttgcgtc ttgacctagc ctcttatcgt
    22561 gagttagaag cctttacaca atttggctca gatctagatg cagcaacgca agcaaaatta
    22621 aatcgtggtc gtcgtactgt tgaaatccta aagcagccac tgcacaagcc cttgcctgtt
    22681 gaaaagcagg tggtcatttt gtacgctttg acgcatggat ttttagatga tgttcctgta
    22741 gatgatattt tagcctttga agaagcactt tatgactact ttgatgcgca ttatgatcac
    22801 ttatttgaaa caatccgtac aaccaaagac cttccgcagg aggctgagct ggacgttgct
    22861 attcaggcct tcaaagcaca gtcaaacttt aaataaaaga ggggggtact agtatggcag
    22921 gctctctaag tgaaattaag gctaaaatca tttcaaccga aaaaacaagc aaaatcacta
    22981 gcgccatgcg tatggtttct tctgcaaagc ttgttaaatc tgagcaagca gctcgtgatt
    23041 ttcaaatcta tgcttcaaag attcgtcaga ttacaacaga cttactgaaa tcagacctga
    23101 caacaggctc agataatccc atgctggtgt ctcgtcctgt gaaaaagaca ggctatattg
    23161 ttattacctc tgataaagga ctggtcggtg gttacaattc aaaaatctta aagtccatta
    23221 tggacatgat tcaggaatac catgccgctg gcgattatga gattatctca attggcagca
    23281 tcggctcaga tttttttaag gccagaggta tgaatgttgc ctttgagctg cgcggcctag
    23341 cagatcagcc aagctttgat caggtcggaa ggattatctc tcagtctgta ggtatgtttg
    23401 tcaatgagat ttttgatgag ctgtacgtct gctacaatca ccatgtcaat agcttgacga
    23461 gccaggttcg ggttcagcgc atgctgccga tttctgattt ggttgccgag gaggccgcag
    23521 aagaaggtgt cactggattt gaattagagc caaaccgtca tgtgattttg gagcagctgc
    23581 tgccgcaatt tactgaaagc ttaatttatg gtgcgattat tgatgcaaaa acagcagagc
    23641 atgctgctgg catgactgca atgcagactg ccactgacaa tgccaagcat gtgatcaatg
    23701 atttgaccat ccagtacaat cgtgcgcgtc aggcggccat tacacaagaa attacagaaa
    23761 ttgtagctgg tgctaatgca cttgaataag cttattgtat gctgatagcg ctctagcaga
    23821 gacctattag cacttaatgt catcttcaaa gctagatgac atttgggatt aatgagctag
    23881 gggcctttta cccttagcta ctcgaattta gaaaaattca gcttaatccc ctactatcga
    23941 atataaggag aaaaacatga gctcaggcaa aattgctcag gttgttggtc cagttgtaga
    24001 cgttgtgttt gcgagtgggg acaaactacc agagattaat aatgcgttga tagtttataa
    24061 agatggcgat aaaaagcaaa aaatcgttct cgaggttgcc ctagagcttg gagacggtat
    24121 ggtacgtaca attgctatgg aatcaaccga tgggcttaca cgtggattag aggttcttga
    24181 tactggtcgt gccattagtg taccagttgg taaagagact ctaggtcgtg ttttcaacgt
    24241 tcttggtgaa accatcgacc tagaagcacc atttgcagat gatgttaatc gtgaaccgat
    24301 ccataaaaaa gcaccagcct ttgatgaatt gtcaacatca tcagaaattc ttgaaacagg
    24361 tatcaaggtt attgacctgc ttgcccctta cttaaagggt ggtaaggtcg gtcttttcgg
    24421 tggtgccgga gttggtaaaa ccgttcttat ccaagaatta atccacaata tcgctcaaga
    24481 gcatggtggg atctcggtat ttaccggtgt tggtgagcgt acgcgtgaag gaaatgacct
    24541 ttactgggaa atgaaggaat caggcgttat tgaaaaaaca gccatggttt ttggtcagat
    24601 gaatgaacca ccaggagccc gtatgcgtgt tgccttgacc ggcttgacaa ttgctgaata
    24661 tttccgcgat gttgaaggcc aagacgtcct gctcttcatt gacaatattt tccgctttac
    24721 tcaagcaggc tcagaggtat cagcccttct aggtcgtatg ccttcagccg ttggttacca
    24781 gccaacactt gccactgaaa tgggacaatt gcaagagcgt atcacctcaa cgaaaaaagg
    24841 ctctgttacc tctatccaag ccatctacgt gccagctgat gactacactg atccggcgcc
    24901 ggcaacagca tttgctcact tggattctac aactaacctt gagcgtaagc tgacgcagat
    24961 ggggatttac ccagcggttg atccactggc ttcaagttca cgcgcgctgt caccagaaat
    25021 tgttggtgag gagcactatg cagtagccac agaggttcag cgtgtcttgc agcgctatcg
    25081 tgaattgcag gatatcattg ctatcttagg tatggacgag ctgtcagaag aggaaaagac
    25141 attggtagga cgtgcgcgtc ggattcagtt cttcttatcg caaaacttta acgtcgcaga
    25201 acagtttaca ggccttcctg gctcttatgt tccagttgcc gaaaccgttc gtggcttcaa
    25261 ggaaatccta gaaggaaagc atgaccacct tccagaagac gcctttcgtg ctgttggacc
    25321 aattgaggac gtgatcgaaa aagctaagaa aatgggcttt tagtgaggtg atgccatgac
    25381 acaaatgact gttcaggtgg ttacgccaga tgggatcaaa tatgatcatc atgctaagtt
    25441 catctcagta acgacaccag atggtgagat ggggatctta cctaaccaca tcaatgtgat
    25501 tgctccttta caggtgcatg aaatgaagat tcgtcgtgtc agtgaagacg atcgcgttga
    25561 ttgggttgct atcaatggtg ggatcattga gatcaaagac aacgtggtta ccattgttgc
    25621 agattcagcc gaacgtgatc gtgatattga tgttagccga gcagagcggg caaaattgcg
    25681 agcagagcgt gacattgcag aggctgaaac cactcatgat attgatgagg tgcggcgtgc
    25741 taaggttgct ttgcgacgtg ccttgaaccg catcaatgtt agtaaaaaat agtaaaatga
    25801 gtctaaccta ccaatttaac caagacagag cgagtagcgc tgcttaggaa agggtgtaga
    25861 tagactcttt tatcttttta tagaaaaaat accctcttt
//
LOCUS       DARYXW010000020        25376 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.020, whole genome shotgun sequence.
ACCESSION   DARYXW010000020 DARYXW010000000
VERSION     DARYXW010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25376
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.020"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(<1..980)
                     /locus_tag="TV191_000675"
     CDS             complement(<1..980)
                     /locus_tag="TV191_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEL1507211.1"
                     /translation="MQEKIYDITIIGGGPVGLFAAFYAGLRGMTVKIIESLSELGGQP
                     AVLYPEKVIYDIPAYPALTGAELTQKLIEQLSRFDDRIAVCLKEEVLSFEKADGNFVI
                     QTSKARHYSKAIIVACGNGAFAPRTLGLDNEQLFADHNLFYNVHSLNQFAGKRVVICG
                     GGDSAVDWALALDGLAKSVTLVHRRDAFRAHEHSVELLKNSHVTTLTPFVPLALEGEN
                     GFVNKMTIQKVKSEEEITLELDSLIVSFGFSTSNKNLKHWNLDYKRSSLLVSPLFQTS
                     QEGIFAIGDAAAYEGRVDLIATGFGEAPIAVNQAIKYIYPDRDNRPVHSTA"
     gene            complement(980..1711)
                     /gene="trmD"
                     /locus_tag="TV191_000676"
     CDS             complement(980..1711)
                     /gene="trmD"
                     /locus_tag="TV191_000676"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEL1507212.1"
                     /translation="MKIDILTLFPEMFAPLEHSIVGKAKEKGLLDIHYHNFRDHAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDTMDSIQATKPRVILLDPAGKPFHQSYAEELALEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDFVLTGGELAAMTMIDATVRLIPNVLGKQASH
                     QEDSFSSGLLEYPQYTRPYDYRGMKVPDVLMSGHHEHIRLWRMEQSLKKTYLRRPDLL
                     ETYDFSDEEKRIFDKIKSGLSEGEN"
     gene            complement(1701..2219)
                     /gene="rimM"
                     /locus_tag="TV191_000677"
     CDS             complement(1701..2219)
                     /gene="rimM"
                     /locus_tag="TV191_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEL1507213.1"
                     /translation="MEYFSVGKIVNTQGLQGEMRVLSVSDFTEERFQKGARLALFDDK
                     DRFVQEVEIASHRKHKQFDIIKFKGMYHINAIEQFKGYSLKIAKENQGKLAEGEFYYH
                     QIIGLEVYEKDQLVGEIKEILQPGANDVWVVKRQSKRDLLLPYIPSVVLCVDIEKHRV
                     DVEIMEGLDDED"
     gene            complement(2990..3328)
                     /locus_tag="TV191_000678"
                     /pseudo
     CDS             complement(2990..3328)
                     /locus_tag="TV191_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677858.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(3494..3733)
                     /locus_tag="TV191_000679"
     CDS             complement(3494..3733)
                     /locus_tag="TV191_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEL1507214.1"
                     /translation="MDTIENLIIAIVKPLISQPDKLTIKIEDTPDFLEYHLDLDAQDI
                     GRVIGKKGRTITAIRSIVYSVPTLGKKVRLVIDEK"
     gene            complement(3743..4015)
                     /gene="rpsP"
                     /locus_tag="TV191_000680"
     CDS             complement(3743..4015)
                     /gene="rpsP"
                     /locus_tag="TV191_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEL1507215.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRAPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLDWLGKGAQPSDTVRSLLSKAGVMAKFHDQKFSK"
     gene            complement(4446..5063)
                     /locus_tag="TV191_000681"
     CDS             complement(4446..5063)
                     /locus_tag="TV191_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEL1507216.1"
                     /translation="MSSFGVSHSLLKKLFKILGGLSILFSVMLVVYLIRQLDIINNPK
                     ALAHLIKDHLLIGAICFFILQIVQVVVPIIPGGVTTVVGFLAFGPILGFMLNVFGICI
                     GSSILFQLVRRYGKPFILLFLSMEQLQFYEKKLSTKLFERFFILNMISPLAPADALIM
                     ITGLSQMTYKRFLLIILICRPISILTFSYFWIYGGEFLKHILMHY"
     gene            complement(5056..6279)
                     /locus_tag="TV191_000682"
     CDS             complement(5056..6279)
                     /locus_tag="TV191_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1507217.1"
                     /translation="MENWKFALSSIWGHKLRSILTMLGIIIGVAAVVIIMGLGAAMTK
                     RVTDSFSNDQKEVQLYFKAKGDEDNPYAAFAAHENEQEVKPEWLEQIVKAIDGVDSYY
                     YTNNSTSTISFEKKKMDNVAITGVSQDYFKVKKYDIVAGRTLNSKDYKNFSRIILLDT
                     VLADELFGKGNYEQALNKVVSLDSKDYLVVGVYKTDQEVVSFAGGISGGAIMANTQVA
                     SEFHVKEIGSVYLYIGDVKRSLELGNQAAAMLTTLSHVKEGEYAVPDNSQIINDINAQ
                     FSIMTTVVGSIAGISLLVGGIGVMNIMLVSVTERTREIGLRKALGATRLKILSQFLIE
                     SVVLTLIGGLLGLLLAQMCVGVLGNAMQLKGAAVSLDVAAVAIIFSASIGIIFGLLPA
                     NKASKLDPIEALRYE"
     gene            complement(6291..7001)
                     /locus_tag="TV191_000683"
     CDS             complement(6291..7001)
                     /locus_tag="TV191_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1507218.1"
                     /translation="MPDEKKELIQLKSIVKSYQNGDQELQVLKGVDLTVYEGEFVAIM
                     GPSGSGKSTLMNIIGLLDRPTSGDYRLNGTQVEILNDRKLAQVRNEEIGFVFQQFFLL
                     AKLNALQNVELPLIYAGVGVSKRRELAKQFLEKVELGMRMKHLPSELSGGQKQRVAIA
                     RALVNNPSIILADEPTGALDTKTGEQIMRLLTELNKEGKTIIMVTHEPEIADFATRKI
                     VIRDGEITADTTESVRID"
     gene            complement(7001..8263)
                     /locus_tag="TV191_000684"
     CDS             complement(7001..8263)
                     /locus_tag="TV191_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEL1507219.1"
                     /translation="MSKRGKIKLSTKTKGIIAGAVALTVVVIGGVLWKQQQDTISDQN
                     IKLPYSAVNVTEGTIASSTLLSGTVKALSEEYVYFDASKGSDATVTVKVGDQVTQGQQ
                     LVQYNTTVPQAAYDTAVRNLNKIGRQINHLKTYGVPAATTETSKDEETGQETTTTIQP
                     SAQQNASYAQQLQDLNDSYADAQAEVNKAQQALNETVVVSGVSGTVVEVNNDIDPSSK
                     NSQTLVHVATEGKLQVKGTLTEYDLANIKVGQAVKIKSKVYADQEWTGKISYVSNYPT
                     DANAGGSTAGGSGSSSSTGATYDYKIDITSPLNQLKQGFTVSVEVINEAKHALVPVTA
                     IVNKGKKHFVWVYDDSTAKAKKVEVTLGNADAERQEVSAGLKVGDIVIANPDKNIKEG
                     EKLEDVISADTKASKDSKKSSKESEVIK"
     gene            complement(8578..11754)
                     /gene="carB"
                     /locus_tag="TV191_000685"
     CDS             complement(8578..11754)
                     /gene="carB"
                     /locus_tag="TV191_000685"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEL1507220.1"
                     /translation="MAKRTDIKKIMVIGSGPIVIGQAAEFDYAGTQACLALKEEGYQV
                     VLVNSNPATIMTDKEVADKVYIEPLTLAFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     SKAGILQELGVELLGTTLSAIDQAEDRDLFKQLMKELGEPIPESEIVTTVEAAIGFAN
                     AIGYPVIVRPAFTLGGTGGGICSNEEVLRDIVENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDAADNALVVCSMENFDPVGIHTGDSIVFAPTQTLSDVENQLLRDASLRIIRALK
                     IEGGCNVQLALDPNSFSYYVIEVNPRVSRSSALASKATGYPIAKIAAKIAVGLRLDDM
                     LNPVTGTTYAMFEPALDYVVAKLPRFPFDKFERGERRLGTQMKATGEVMAIGRRIEEC
                     LLKACRSLEIGVHHNELKGLDTISDHELVAHIVRAQDDRLFYLSEALRRGYSIEELAG
                     LTKIDLFFLDKLRHIVELEQDLIKKPVDIDLLIEAKRYGFSDQKIAELWQTDAASIRR
                     LRRAYRVLPVYKMVDTCAAEFDSQTPYFYSTYEWENESIKSEKESVIVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEEVMNVIEL
                     EQPKGVILQFGGQTAINLAEQLTKAGVPILGTQLEDLDCAEDRELFEKALKELGIPQP
                     PGKTATNEAEALEAARAIGFPVLVRPSYVLGGRAMEIVENENDLRSYMKTAVKASPEH
                     PVLIDSYILGKECEVDAISDGQSVLIPGIMEHIERAGVHSGDSMAVYPPQHLSKQVQD
                     KIVDYTKRLAIGLNCIGMMNIQFVIQNEQVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQTLKDLGYQDGLYPESSLVHIKAPVFSFAKLAKVDSLLGPEMKSTGEVMGSD
                     LTLEKALYKAFEASYLHMPEYGTIVFTIADDHKSEALILARRFSAIGYQIMATEGTAA
                     FFADQGLDSQLVGKIGDNAHDIPALLRKGQIQAIINTVGTKRVTDKDGQMIRSSAIEQ
                     GVPLFTALDTAVAMLRVLESRTFSIEAI"
     gene            complement(12172..13263)
                     /gene="carA"
                     /locus_tag="TV191_000686"
     CDS             complement(12172..13263)
                     /gene="carA"
                     /locus_tag="TV191_000686"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEL1507221.1"
                     /translation="MAKRLLILEDGTIFEGKPFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQLLVFTYPLVGNYGINRDDYESIAPTCKGVIVSEVSRIASNWRQQMTLDEFLK
                     HKGIPGISGIDTRALTKIIRQHGTMKATMADDGDTLEHLKDQLRATVLPTNGIEQVST
                     KTAYPAPGVGKNIVLVDFGLKHSILRELSKRQCQMTIVPFDITAEEILQLNPDGLMLS
                     NGPGNPEDLPEALEMIRGVQGKIPIFGICMGHQLLSLANGAKTFKMPFGHRGFNHAVR
                     EIATGRIDFTSQNHGYAVERDSLPDCLMVTHEEINDKTVEGVRHRHVPAFSVQFHPDA
                     APGPHDASYLFDEFLDMIDAWQLEQQGKC"
     gene            complement(13286..14221)
                     /locus_tag="TV191_000687"
     CDS             complement(13286..14221)
                     /locus_tag="TV191_000687"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEL1507222.1"
                     /translation="MSVVNNRVALKHLVSMEHLTNEEVLGLISRGSEYKAGKVAIKDN
                     SRHFAANLFFENSTRTHKSFEVAENKLGLRVLDFNADTSAVNKGETLYDTVLTMSALG
                     TEICVIRHPEDDYYQQLIDSPTITASIVNGGDGSGQHPSQCLLDLLTIYEEFGHFDGL
                     KIAIAGDLTHSRVAKSNMQILKRLGAELYFYGPEQWYSSEFDSYGRYMAIDHIIDQLD
                     VLMLLRVQHERHDGSQSFSKEDYHRQFGLTEERYRRLKDSAIIMHPAPVNRDVEIADH
                     LVEAPKARIVAQMANGVFVRMAIIEAILNGRNDKV"
     gene            complement(14279..15538)
                     /locus_tag="TV191_000688"
     CDS             complement(14279..15538)
                     /locus_tag="TV191_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEL1507223.1"
                     /translation="MKDVIYDVEEVPKAGILLGLSFQHLFAMFGATVLVPILVGIDPS
                     VALLSSGLGTLAHLSVTTFKIPAYMGSSFAYIAAMQMLMKTDGIGAVAQGAITGGLVY
                     LVVALVVKAIGNEWIDKILPPVVVGPIVMVIGLSLASTAVSDVMLKDGKYNLLYLLIG
                     LVTLLAIIFFNIYGKGIVAIIPILLGLLVGYLFAILVGMVTGQSIVDFTQVAKAQWLS
                     VPAVAIPFLTYDITLYPSAILTMAPIAFVTMTEHFGHIMVLNSLTKRDYFKDPGLEKT
                     LTGDGLAQVIAGFLGAPPVTSYGENIGVMALNKIFSVYVIAGAAVIAGLLSFVGKVSA
                     LIQSIPTPVIGGISIALFGVIASSGLKILIEAKVDMDNKKNLLIASVILVSGIGGLML
                     QINGLQISGVAFSTLLGIILYQLLPEN"
     gene            complement(15554..16075)
                     /gene="pyrR"
                     /locus_tag="TV191_000689"
     CDS             complement(15554..16075)
                     /gene="pyrR"
                     /locus_tag="TV191_000689"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEL1507224.1"
                     /translation="MKSKVIVDELTMKRAITRITYEIIERNKQLDNVVLVGIKTRGVY
                     LARRIQERLEQLESLHLAVGELDTKPFRDDMRVEEDTTSMPVDITGKDIILVDDVLYT
                     GRTIRAAIDNLVSLGRPGRVSLAVLVDRGHRELPIRADYVGKNIPTSKTEEIVVEVVE
                     VDGQDRISIVDPG"
     gene            16437..17051
                     /locus_tag="TV191_000690"
     CDS             16437..17051
                     /locus_tag="TV191_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEL1507225.1"
                     /translation="MNDITRKINHKQLIQITTILGIIVTIVILFYLQQHPNLFAVGGP
                     FQTYLMELGILAPCLFILLQIIQVVYPIIPGGLTCVLGHVVFGPFWGFLYNTLGIFIG
                     SLLSFMLARKYGEQFAKAFVSDDTYNKYIPYLNKGKYFERFLITAFILPGFPDDFLCM
                     VAGLSSMSIKTFTSIFLISKPITLYIYTLLAYQGIQIVGQVLQS"
     gene            complement(17132..18022)
                     /locus_tag="TV191_000691"
     CDS             complement(17132..18022)
                     /locus_tag="TV191_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEL1507226.1"
                     /translation="MEIKITESGHRLDKALADLTPLSRSQANDQIKQKRVLVNGLPKK
                     AKYIVQVGDCISYHIPEESSLDYQAQDIPLDIVYQDDVLAIINKPQGMVVHPSAGHST
                     GTLVNALLYHIKDLSSINGVIRPGIVHRIDKDTSGLLMVAKTDKAHQLLADELKAKKS
                     LRKYVAIVHGNLPKDRGVIEAPIGRSEKDRKKQTVTAKGKEALTLFKVLERFGHYTFV
                     ELQLETGRTHQIRVHMAYIGHPLAGDPLYGPRKTLAGKGQFLHAQTLGLTHPVTGEEL
                     VFTVEPPEIFQRTLEQLRQG"
     gene            complement(18012..18470)
                     /locus_tag="TV191_000692"
     CDS             complement(18012..18470)
                     /locus_tag="TV191_000692"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEL1507227.1"
                     /translation="MKRISFIMAAIVLMILDQLSKWWTVTHIELGQVKPFIPGLVSLT
                     YLQNRGAAFSILQNQQWFFTIITVLVVGYAIYYVLKHPKASFWLQLSLLLIISGGLGN
                     FIDRLRLSYVVDMIHLDVINFAIFNVADSYLTIGVLLLVICLWKEEDYGN"
     gene            complement(18698..19627)
                     /locus_tag="TV191_000693"
     CDS             complement(18698..19627)
                     /locus_tag="TV191_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEL1507228.1"
                     /translation="MNIQQLRYVVAIANNGTFREAASKLFVSQPSLSVSVKDLETELG
                     FQIFRRTTAGTVLTSQGLLFYEKALEVVKCFDSLEKEFSQSALEPNEFSIASQHYDFL
                     PALITAFSQKHAGHKVFRVFESTTMQILDEVAQGNSELGIIYLNAQNRQGLFQRMDKL
                     ALDYVELLSFTTHIYLSKNHPLAQRKALFLEDLQGLPAVRFTQEKEEYLYYSENFIDT
                     SKSPHIYTVSDRATLNGILERTAAFATGSGFLDQQSVNGIKVIPLRDHMEHKMIYVKR
                     RDKNLSAAALHFVTILQDYFEHRKEKQAIDNGT"
     gene            complement(20034..20327)
                     /gene="rpmA"
                     /locus_tag="TV191_000694"
     CDS             complement(20034..20327)
                     /gene="rpmA"
                     /locus_tag="TV191_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEL1507229.1"
                     /translation="MIKLNLSNLQHFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVSG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(20349..20681)
                     /locus_tag="TV191_000695"
     CDS             complement(20349..20681)
                     /locus_tag="TV191_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEL1507230.1"
                     /translation="MIKVRLTKDAAGWTEMLITGHAGSGEYGFDVVCASVSVLAFNLV
                     NSVEQMTGLEPALEMVDGGGFLRVTKPEGFTEQQEQVWQILFESVVIGLENLAEHLSE
                     YVQKPVMN"
     gene            complement(20694..21008)
                     /gene="rplU"
                     /locus_tag="TV191_000696"
     CDS             complement(20694..21008)
                     /gene="rplU"
                     /locus_tag="TV191_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEL1507231.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAIYVEKIDAEAGAEITFNEVVLVG
                     GDKTVVGTPVVEGATVVGTVEKQGKQKKVVTFKYKPKKGSHRKQGHRQPYTKVVINAI
                     KA"
     misc_feature    complement(21042..21116)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(21238..22431)
                     /locus_tag="TV191_000697"
     CDS             complement(21238..22431)
                     /locus_tag="TV191_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEL1507232.1"
                     /translation="MLKDFQYKKTMLSVLTLIVVILVFGLAFDLLGMSKKGTQTKSKT
                     PQKTQTARVVANGDILIHDILYMSAKKADGSYDFNPYFEYVKDWISQADLAIGDYEGT
                     ISPDYPLAGYPLFNAPEAIAAALKHTGYDVVDLAHNHILDSRLEGALNTKRVFADMGI
                     DSIGIYEQDRSKENILIKKVNGIKIAILGYSYGYNGMEATLSQEEYDKHLSDLNEEKI
                     QKDILRAEKEADITIVMPQMGTEYALEPTAEQKTLYRKMIDWGADVVLGGHPHVVEPA
                     ETIVKDKEKKFIIYSMGNFISNQRLETVDDIWTERGVLMDLTFEKKGQKTKIKTVKAH
                     PTMVLAKPKGLYGSEGYELYSYRTMVLEDFIKGGRYYDKIDPETQEKAAIAYKEMNAL
                     VNLKW"
     gene            22696..23313
                     /locus_tag="TV191_000698"
     CDS             22696..23313
                     /locus_tag="TV191_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3862 domain-containing protein"
                     /protein_id="HEL1507233.1"
                     /translation="MKHNSFSRSLLLPLLICSLSACSSHTEKKDHTKDATAITDTRKA
                     EHQDIRANMEKVKLATASTDFKGGSSLEELITIFGQPSQHEEKAAGSVTLDSYTWQFD
                     HVTVNINLYENSSIVKTIANFAFIRDLTLSLKDYNSLKKGMTYDEVKQLLTEPDNYSQ
                     ANSSEKETIQAIWISGLKAQTQGANIALTFENNQLTEMSQVGLED"
     gene            complement(23611..24840)
                     /locus_tag="TV191_000699"
     CDS             complement(23611..24840)
                     /locus_tag="TV191_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1507234.1"
                     /translation="MRGLIKNVVFRTLTVSNFLSALGSYIYNIVFIIYATTLPYSHIA
                     VFIANIITIIPMVFTFWIGVKADKTKRKTRNLIVIGFIQSLLFTLVALLMTNQTFLVF
                     AFVGFLNVVSDILSDYKNGLRLPIMQKNIESEKLYEAYSFAQFIGYLSSIAGQALGVW
                     LLTTSGNNYAFVALINAISFLLSSVVLLKNRQKLRHDVVEASEAGVSLMKQFKVMYTR
                     MTETFKKIDHISFVMLLLSILTLNAIGGAINSIYHFYLMDHQLFHFHYGQSLVIVDAV
                     TIIGAMLGNLTPKDYFSRLSISKLVQTQGIAFLLVGVSNALQLPAIIGVLCLAFAAYI
                     MGKATPKLDALLMENLPSDMLAQSNNFLGLLFSLSLPVGVFIFSFLALYNMTLCWILF
                     MVLSLAALALSTSSTRG"
     gene            complement(24875..25366)
                     /locus_tag="TV191_000700"
     CDS             complement(24875..25366)
                     /locus_tag="TV191_000700"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507235.1"
                     /translation="MMQLKSEVNLGLNGLAGVLFYLSSISYDNEIIEKGIDFILESLV
                     EDSDGNRGVLISENSVSPYLSNGTAGIVQLLIYVNSDKYIKDIKNLSESLLVEFAQFS
                     GLWNGMLGIAMTLLQVFRLTNDTLYLEKACELLISSKIMSEHHIKLQYEFRYAVSIFN
                     QVK"
BASE COUNT         7646 a         5881 c         4487 g         7362 t
ORIGIN      
        1 gctgttgaat gaacaggtct attatctcta tcaggataaa tatacttaat cgcttggttg
       61 acagcaatcg gtgcctcacc aaagccagtg gcaatcaaat caaccctgcc ttcataagct
      121 gctgcgtcac cgatcgcaaa aatcccttcc tgacttgttt gaaagagggg agagacaaga
      181 agacttgagc gcttataatc tagattccaa tgctttaggt ttttattaga tgtagaaaag
      241 ccaaagctaa caatcaggct gtctagctca agcgttatct cctcttctga ctttaccttt
      301 tgaatagtca ttttgttgac aaagccattt tctccttcga gggcaagggg aacaaagggg
      361 gtaagggtag taacatgaga gttttttaac aattctacgc tatgctcatg agccctaaag
      421 gcgtctcgcc ggtgcacaag ggtaacactc ttagcgaggc catctaaggc taaagcccag
      481 tccacagcag aatctccacc accgcagatc acaaccctct taccagcaaa ctgattcaag
      541 ctgtgaacat tataaaagag attatgatca gcaaataact gctcattgtc taagcccaag
      601 gttctaggcg caaaggctcc attgccacaa gcaacaataa tggccttaga ataatgtctg
      661 gccttgcttg tttgaataac aaagttccca tcagccttct caaaagacag gacctcttct
      721 ttcaggcata ctgctatgcg atcgtcaaat ctgcttagct gctcaataag cttttgtgtt
      781 agttccgctc cagtcagggc cggataagct ggaatatcat agataacctt ttcaggataa
      841 agaacagccg gctgtcctcc tagctctgac aggctttcaa taatcttaac cgtcatgccg
      901 cgcaggcctg cataaaaggc tgcaaataag cctaccggac ctccaccaat gatggtaatg
      961 tcatatattt tttcttgcac tagttctctc cttcacttag ccccgatttg attttatcaa
     1021 aaatcctttt ttcctcatca gaaaaatcat aagtctctaa taaatctggt cttctcaaat
     1081 aggtcttctt taggctttgc tccatacgcc agagacgaat atgctcatga tggccactca
     1141 ttaggacatc aggcaccttc atgccacgat aatcatatgg ccttgtatac tgtgggtact
     1201 ccaagagccc agatgagaag gaatcctctt gatgactggc ttgctttcca agcacattag
     1261 gaatcagtct cactgttgca tcaatcattg tcatagcagc cagctcacca ccagttaaga
     1321 caaaatctcc cagagatatt tcatcggtaa caagtgtctt aatgcgttcg tcatagcctt
     1381 cgtaatgccc acaaataaaa attaactctt cctcaagagc taattcttca gcataagact
     1441 gatgaaaggg ttttccagca ggatccagta aaatcactcg aggctttgta gcctgaatgc
     1501 tatccatggt atcaaaaata ggctgcgctc tcagcagcat gccctgccca ccaccatatg
     1561 gctcatcatc aacatgccta gctttctccg catggtcacg aaaattgtgg taatgaatat
     1621 ctaaaagccc cttttcctta gcctttccaa caatggagtg ctccaaagga gcaaacattt
     1681 ccgggaaaag ggttaaaata tcaatcttca tcatctaagc cttccataat ttcaacgtct
     1741 acccgatgct tttcgatatc aacacaaaga acaaccgatg ggatataagg aagcaacagg
     1801 tcacgcttgc tttgccgttt gaccacccaa acatcatttg caccaggctg taaaatttcc
     1861 ttaatctctc ctactagctg gtccttttca tacacctcca gaccaataat ctggtgatag
     1921 taaaattctc cctcagctag cttaccctga ttctctttag caatcttaag actgtagccc
     1981 ttaaattgct caatagcatt gatgtgatac attcccttaa acttgataat gtcaaactgc
     2041 ttatgcttgc gatgactcgc aatctcaacc tcctgcacaa aacgatcctt gtcgtcaaac
     2101 agggctagtc tagcaccttt ttgaaatcgt tcctcagtaa agtcactcac agacagcacg
     2161 cgcatttctc cttgcaagcc ttgagtattg acaatcttcc caacgctaaa atattccatc
     2221 cttactccta atcatcttag actctatagc ttgatagacc tctatttttt catgacaaca
     2281 cgacatgagt atcatcatcc taagcactct agcctatcgt taaagctccc cttattgtaa
     2341 catgttctgc cttattttgc acttctcttt caaaaaatta atctcccagt tatagcagct
     2401 aagcctagca agcaaagccc ttgatgctaa agaatcctga tccccctata attaacaaat
     2461 catcatgact tgccttgccc aagctcagtc aagtgaatga aaaatctgct aaacaatagc
     2521 cttgcgcctc gctgacaagc atcaaaaaaa cactcctgct ggcaatctga actgcccccc
     2581 aattgttaga ttttatgtcc aacttttggg ggtcagtaca atctagtaaa ctagaatcag
     2641 gagtgtttca ttatagccca acaagcaaaa ggaatacttg gtaaaagcaa agctgacttg
     2701 cattgagaag attaaaacca ttcaatctgt cacaataatt atggaaacat tgggaattta
     2761 aaaacaagta tcagctgcta tcaacctgtg gggaaatagt ctacctatgc ctatcgggcc
     2821 atccatcata ggtcctctca agaaatgatg agagcctcat caaccagcta tcatcgcctt
     2881 aaaggagaat gacgaatgtt atcgtaggtg tcccaagaaa tactacaaaa gaaactcatt
     2941 ttgatcttaa tgctctaaag ggcttgacct tacgtcaact gataaagctc tacttcatag
     3001 catcgttttg ctttgcagct tttctatacc tcatgtctaa taaaagacat aagcttgccg
     3061 ataagaacat taccccaaca tagaagaata gattggtctc atcgccagtc tttagtaaga
     3121 tggtattttg atgcttcatc ggtttggtag ctgttgaaac atgcggacac ttggtttcat
     3181 ttgtcgtcga tggtattgtc ggacgacttg gcttagtgtt attaggctta tgattgcctt
     3241 cactactgct tacctttttc ttccactgtg caaacaattc attaggaaac ggcaggtcat
     3301 tatctaccct aatgtcatca cctacctttt ttaacctcct gctcgatctc ttgttgcata
     3361 caaaatgtta tacagatact tctgtcagat agagttcttg cttttgtctc ttgacttggt
     3421 gattcaaaac acaaaaaaag cctgctagat agaactagca aggctttaag attagtcttg
     3481 ttcaaaatag aacttatttt tcatcaatga ctaatcgaac cttttttcct aaagttggca
     3541 ccgaatagac aatcgatctt atcgctgtga tggtacgacc tttctttccg ataacacgac
     3601 cgatgtcttg agcatccaag tcaagatggt actctaaaaa atccggagta tcttcaattt
     3661 taatagtaag cttatctggt tgtgaaatca agggcttcac aatagcgata atgagatttt
     3721 caatggtatc cataggcttt tattacttag aaaatttttg atcgtggaat ttagccataa
     3781 ccccagcttt agatagaagg ctacgaactg tatcagaagg ttgtgcacct tttcctagcc
     3841 aatcaagaac acgatcttct ttaagagtta cttgattttc agctacaagt gggttgtagg
     3901 ttccaactgt ttcgatgaaa cgaccatcac gtggtgcacg tgaatctgca acgttgatac
     3961 ggtagaaagg ttttttctta gaacccatac gagttaaacg gatttttact gccattttaa
     4021 tatgtctctt ttctttaaat gataatagtc aagaaatgta gtcctgctca tttctcacct
     4081 aactagtata ctttactttt gattatgtgt caagtttttt tcttgacact tttttatgat
     4141 cataatacta ctcaacatct tcaatcagct aagctgctta gatgacatca aacagcaggc
     4201 agctgctctt ataagagcat acaactccaa actaacctac tctagtgatc cttagccgtc
     4261 aataatggga tcaggcaagc ataactcccc gtcaaaggag cggtttgttt cacagcaaaa
     4321 aggcgaaata aactgacaat cacatcaaaa aggacgagcc cctaaacatg caggagctcg
     4381 tccttttacc aatatgactt agtctctcct tgcttttaag gctagggtat tagctaagcg
     4441 ttacactaat aatgcatcaa aatatgctta agaaactctc caccataaat ccaaaaataa
     4501 ctgaaggtca aaattgaaat gggtctacaa attaggataa tcagtaaaaa gcgcttgtag
     4561 gtcatctgac tcaatccagt aatcataata agagcatcgg caggggctaa gggggaaatc
     4621 atattgagaa taaagaaacg ctcaaataat ttcgttgata gcttcttttc ataaaactgt
     4681 agctgctcca tacttaaaaa cagtaagata aagggctttc cgtatctcct caccaactga
     4741 aacaaaatag aagatccaat gcagatacca aacacattta acataaagcc taatatagga
     4801 ccaaaggcta gaaagccaac gactgttgtc acaccaccag gaatgatagg aacaactacc
     4861 tgcacaattt gcaagataaa aaagcaaatg gcaccgataa ggagatgatc cttgattaaa
     4921 tgggctaaag cctttggatt attaataata tctagctgcc taataaggta gacaacaagc
     4981 atgacggaga acagaattga taggccacca agaatcttaa acagcttctt taacaacgaa
     5041 tgtgaaacac caaagctact catagcgcaa agcctctatc ggatcaagct tgcttgcttt
     5101 gtttgctggc agcaatccaa aaataatacc aattgatgcc gaaaagataa tagctacagc
     5161 cgcaacatct aaggaaacag ctgctccctt taattgcatc gcatttccta gcacacctac
     5221 acacatctgt gctagcagca gccctaaaag accgccaatt aacgtcaaca ccactgattc
     5281 aatcaaaaat tggctaagta tcttcaagcg cgttgctccc aaggcttttc gcaagccaat
     5341 ttcacgtgta cgctctgtta cagataccag catgatgttc ataacaccaa taccacccac
     5401 aagaagggaa attcctgcaa tggacccaac aactgtggtc atgatactaa attgtgcgtt
     5461 aatgtcattg ataatttggc tattgtcagg aacagcgtac tcgccctcct taacatgaga
     5521 cagtgtggtc agcatagcag ctgcttgatt tcctaattca aggcttcgct taacgtcgcc
     5581 aatataaaga taaacagagc caatttcctt gacatgaaat tctgaagcca cctgggtatt
     5641 ggccataatg gctcctccag aaatcccacc agcaaacgaa acaacctcct gatcagtctt
     5701 gtaaacacct actacaaggt agtccttact atctagacta accaccttat ttagagcttg
     5761 ttcataattg cctttgccaa ataattcgtc agccaagaca gtatctaata ggataatgcg
     5821 agaaaaattt ttataatcct tgctatttag cgtcctacct gcaacaatat catatttttt
     5881 gactttaaaa taatcctgac taaccccagt gatggccaca ttgtccatct tctttttctc
     5941 aaaggaaatg gtagaggttg aattattggt atagtaataa gaatctaccc catcaattgc
     6001 tttgacaatc tgctctagcc attcaggctt gacctcttgc tcattttcat gcgctgcaaa
     6061 ggccgcgtaa gggttgtcct catctccttt tgccttgaaa taaagctgaa cctctttttg
     6121 gtcatttgaa aaggaatccg taaccctctt tgtcatggca gcaccaagcc ccatgataat
     6181 cacaacagca gctacaccga taataattcc cagcatggta agaatcgaac gcagcttgtg
     6241 cccccagatt gaactaagag caaatttcca attttccatc acttttcctc ctagtcaatc
     6301 ctgacacttt ctgttgtatc agctgtgatt tcaccatcac gaataacaat ttttcgagtg
     6361 gcaaagtccg caatctctgg ctcatgagta accataataa tagttttgcc ttccttattc
     6421 agctccgtca aaagcctcat aatctgctca ccagtctttg tatctagggc accagtcggc
     6481 tcatcagcta agataataga cgggttatta accaaggctc ttgcaatggc aaccctttgc
     6541 ttttgaccac ctgataactc tgatggcaaa tgcttcattc gcataccaag ctcaaccttt
     6601 tccaaaaatt gcttagccaa ttcacgacgc tttgatactc caactccagc ataaatcaag
     6661 ggaagctcaa cattttgcag ggcatttagc tttgctagta aaaagaactg ctgaaagaca
     6721 aagccaatct cttcgtttct cacctgagca agctttcgat catttaggat ctcaacctgt
     6781 gtgccattga gacgataatc acctgaggtt ggtctatcta ataagccgat gatattcatc
     6841 agggttgatt tccctgagcc agaaggcccc ataatagcga caaattcacc ctcatataca
     6901 gtcaaatcca cgccttttag gacctgtagc tcctgatcac cattttgata gcttttaaca
     6961 atgcttttta attgtattaa ttcttttttc tcatctggca ctacttaatc acctcggatt
     7021 ctttactgct ttttttagaa tcttttgatg cctttgtgtc tgcggaaata acgtcttcta
     7081 gcttttcacc ctctttgatg ttcttatcag ggttagcaat gacaatatct cccaccttta
     7141 gacctgcact tacttcttgt ctttcagcat cagcattgcc tagggttact tcaacctttt
     7201 tagcctttgc agttgagtca tcatagaccc agacaaaatg cttcttgcct ttgttaacga
     7261 tagcagtaac tggtactaag gcatgctttg cttcgttgat aacctcaaca gacaccgtaa
     7321 agccttgctt tagctggtta agcggactcg tgatatcaat tttgtagtca taggtcgcac
     7381 cagttgagct tgatgagcct gagcctcctg cagttgaacc acctgcattg gcatcggttg
     7441 ggtagtttga cacataagaa atctttccgg tccactcttg atcagcatag acctttgatt
     7501 taatcttcac agcttgtcca accttaatat tggctaaatc atactctgtt agggtccctt
     7561 tgacctgtaa cttgccttcg gttgcgacat gaaccaaggt ttgactgttt tttgaagacg
     7621 ggtcaatatc attattaacc tctacaactg tccctgaaac accactgaca actactgttt
     7681 catttaaggc ctgctgtgct ttattgacct ctgcttgagc atcagcatag gaatcattta
     7741 aatcctgcaa ttgctgagca tagctagcat tttgctgggc tgagggctga atggttgtgg
     7801 tggtttcttg ccctgtctcc tcgtccttgc ttgtctcagt agttgctgct ggaacaccat
     7861 acgtttttaa atgattaatc tgacgcccaa ttttattgag attgcgaaca gcggtgtcat
     7921 aagctgcctg tggtacagtt gtattgtact gtactaactg ctggccttgt gtgacctgat
     7981 ctcctacctt aaccgtaacg gtagcgtctg agcctttgct agcatcaaaa taaacatatt
     8041 cttctgaaag agctttaaca gtaccagaga gtaaggttga agaggctatt gtcccttctg
     8101 ttacatttac cgcagaataa ggtagcttga tattttgatc agagatagta tcttgctgtt
     8161 gcttccacaa tactccaccg ataacgacta cagttagtgc aactgcacct gcgataatgc
     8221 ctttggtttt cgttgataac tttatctttc ctcttttaga catttctgtc ctcccctttt
     8281 gtactatttt tgtaagacaa gtatatgatg tttttaaaaa cttgtcaaga atttcttgga
     8341 taagcttaat aaagcagcct cttcatcatg tagatgacaa ctctattata atggtttttc
     8401 aagctgtact agcttacact tttgtaatat taaaaagagg caaagacaaa aagagttgtc
     8461 ctttaacttt attacacagt ctcattcatt aaaaagcgaa caagcctagt tttcaaaatc
     8521 tcagaaaact agacttgttc gtttgtttag acttttctct cagtctcttc atcaggttta
     8581 aatagcttct atactaaagg tacggctttc aagaactctc agcattgcta ctgctgtatc
     8641 caatgctgta aacagaggaa ctccttgttc gattgctgag cttctgatca tctgcccgtc
     8701 cttatcagtc actcgttttg ttcctacggt attaataata gcttgaatct gcccttttct
     8761 cagtaaggct gggatatcat gagcattgtc gccaattttt ccaactagct gtgaatctag
     8821 cccttggtca gcaaagaaag cagctgtgcc ttcggttgcc atgatctggt agccaatagc
     8881 actaaagcgt ctagctaaga tcagagcctc cgacttatgg tcatcagcga tggtaaaaac
     8941 tattgttcca tattccggca tgtgcagata gctagcttca aaggctttgt aaagggcttt
     9001 ttcaagtgtt aaatcagagc ccatgacttc accagttgat ttcatctcag gccctaaaag
     9061 gctatccacc ttagcgagct ttgcaaatga aaaaaccggt gccttgatat gaacaagcga
     9121 gctttcagga taaaggccat cttgataacc taagtctttt aaggtctgac ccagaataag
     9181 cttcgtagcg acttgtgcca ttggaatatt ggttactttt gataaaaatg gcactgtccg
     9241 actggcacga ggattgacct caatgacata gacctgctca ttttggatca caaattggat
     9301 attcatcatg ccaatacagt ttagccctat agcaagacgc ttagtgtaat caacaatctt
     9361 gtcttgaacc tgtttagata ggtgctgcgg cgggtacaca gccattgaat ctcctgaatg
     9421 cactcctgct ctttcgatat gctccatgat ccctgggatt aagactgatt gaccgtcaga
     9481 gattgcatct acctcgcatt ccttaccaag gatataagaa tctattaaaa caggatgctc
     9541 aggactagcc ttgacagctg ttttcatgta ggagcgtaaa tcgttttcat tttcaacaat
     9601 ttccattgct cggccaccaa gaacataaga gggtctgacc aataccggaa agccaatggc
     9661 acgcgctgcc tctaaggcct ctgcctcatt ggtggctgtt ttcccaggag gctgagggat
     9721 ccccagctcc ttcaaggctt tttcaaaaag ctccctatcc tcagcacaat ctaagtcctc
     9781 tagctgtgtg cctaaaatag gaactccggc cttggttaac tgctctgcta gattaatagc
     9841 agtttgtcca ccaaactgta ggattactcc ctttggctgc tctaattcaa taacgttcat
     9901 gacctcttca aaggttaagg gttcaaaata aagcttgtct gatatcgaaa aatctgttga
     9961 cactgtttca ggatttgaat tcatgataat ggcttcatag cccgcagcct gaatagcctt
    10021 gacagaatgt acggttgcat aatcaaactc aactccctga ccgatgcgga taggaccaga
    10081 gccaaggacg ataacagatt ctttctcgga tttgattgat tcgttttccc actcataggt
    10141 cgagtaaaaa taaggcgttt gtgagtcaaa ttcagctgca caggtatcaa ccatcttata
    10201 aactggcaag acacgatagg ctcgccttaa ccgtctaata cttgcagcat cagtttgcca
    10261 aagctctgca attttttggt ctgaaaaacc atatcgcttg gcttctatca gcaaatcgat
    10321 atcaactggc tttttaataa ggtcttgctc cagttctacg atatgacgta atttatccaa
    10381 aaagaataaa tcaatcttgg ttaagccagc tagctcttca atactatagc cacgacgaag
    10441 ggcctcagaa agatagaata gacgatcgtc ctgtgctctt acaatgtgag caaccagctc
    10501 atgatcactg atagtatcta gacccttcag ttcgttatgg tgtactccaa tttccaacga
    10561 gcgacaagcc tttaagagac attcctcaat acggcgtcca atagccataa cctcaccagt
    10621 tgctttcatc tgggttccta gacgacgctc cccccgctca aacttgtcaa atggaaagcg
    10681 tggcagcttg gcaaccacat aatcaagagc tggttcaaac atggcatagg tggttcctgt
    10741 gaccggatta agcatgtcat caagccttaa gccaactgca attttagcag ctattttagc
    10801 gattggataa ccagttgcct ttgaagccag tgctgatgag cgagataccc gcggattaac
    10861 ctcaatcaca taatagctga agctattggg atcaagtgcc agctgaacat tacagcctcc
    10921 ttcaatctta agggcacgaa taattctcaa gctagcatca cgaagcagct gattctcaac
    10981 atctgatagg gtttgtgtcg gggcaaaaac gattgaatct ccagtatgta tccctactgg
    11041 gtcaaaattt tccatactgc aaacaaccag cgcgttatca gcagcatcac gcatgacctc
    11101 atattcaatc tctttaaagc cggcaatgga gcgttcaatc agacactggg tgacaggaga
    11161 tagcttcagg ccattctcca caatatctcg caagacctct tcattggagc aaataccacc
    11221 tccagtgcct cccagagtaa aggcggggcg gacaataaca gggtagccaa tggcatttgc
    11281 aaagccgata gccgcctcta ctgtcgtcac aatctctgat tctggaatag gctctcccaa
    11341 ctctttcatt aattgcttaa ataaatcacg atcctctgcc tgatcaatag cagataaggt
    11401 tgttccaagc agctccactc ctaattcttg taaaatacca gccttagaca gttccatcgc
    11461 catgttaaga ccggtctgcc cacctaaggt cggcagcaag gcgtctggtc tttcctttct
    11521 taagatacga ctaacaaatg ccaacgtcag gggctcgata taaaccttat ctgcaacctc
    11581 tttgtctgtc ataattgtcg cagggttaga attaaccaga acaacctgat agccctcttc
    11641 ctttaaggct aaacaagcct gtgttcctgc gtaatcaaat tcagctgcct gcccaataac
    11701 aataggacca gaccctatca ccatgatttt tttaatatct gtacgttttg ccataatatc
    11761 tggtacaaaa ggccttaaca atccgaataa aataatgcaa gcacctaaca ttaaagcatc
    11821 acaatctatt ttttactagg atttgtacct gtactcagct gcagcaagcc ctttgtacct
    11881 actcctttca ttatttgccg tctcacaggg cggcattaaa taaaacactt aacagtctgt
    11941 cacatgagac gatgagtaca agatcaagta acccttagct cagcaagtat agatgactta
    12001 attgatatag tctttttact tctaaagagg gcgatcttgc cagcaaatac tagtcataac
    12061 ccgcggcaga gcgatcattt cccactagtc tatctgctgc ctgactcaag ctgtttcatg
    12121 acagctgatc aagcctttgg tgcttgcttt ttgatctgct agcacacttg attaacattt
    12181 gccttgctgc tctagctgcc aggcgtcaat catatctaaa aattcatcaa atagatagct
    12241 agcgtcatga gggcctggtg cagcgtctgg gtgaaactgc acagaaaagg cgggaacatg
    12301 tcgatgtctc accccttcaa cagttttgtc attaatctcc tcgtgcgtaa ccatcaagca
    12361 gtctggcaag ctgtcgcgct caacagcata accatgattt tgactagtaa aatcaatacg
    12421 tccggtcgct atttctctga cagcatgatt aaagccacga tgtccaaaag gcattttaaa
    12481 ggtcttagcg ccattagcta agctaagcag ctgatggccc atacaaatgc caaaaattgg
    12541 aatttttcct tgaacaccac gaatcatctc caaggcctcc ggcaaatcct ctggattacc
    12601 tggaccattt gatagcatta gaccatctgg gttgagctgt agaatctctt ctgctgtgat
    12661 atcaaagggg actattgtca tctgacattg ccttttggat aattctctta aaatggaatg
    12721 cttcaagcca aagtccacca aaacaatatt tttcccaaca cccggagcgg gataggcagt
    12781 cttagttgac acctgctcaa taccattagt cggaagcaca gttgcacgca gctgatcctt
    12841 taggtgttca agcgtatcac catcatctgc cattgttgcc ttcatcgtac catgctgacg
    12901 aatgattttg gtcaacgctc tggtatcaat tcctgaaatg cctggaatcc ccttatgctt
    12961 taaaaactcg tccaaggtca tttgctgacg ccaattgcta gctatcctgc ttacttcaga
    13021 gacaatgacc cctttgcaag ttggggcaat ggactcataa tcatcacgat taataccata
    13081 attaccaaca aggggatagg taaatactaa gagctgcccg ttataggact ggtctgtgat
    13141 tgactcctgg tagcctgtca ttcctgtatt aaagacaatc tcgccagtga catcaatatc
    13201 tgcaccaaag ggctttcctt caaaaatggt gccatcctct aagataagta accgttttgc
    13261 cattttaacc ccctctaaca tgcctttaga ccttatcgtt tctgccatta aggatcgctt
    13321 cgataatggc catacggaca aatacaccat tagccatttg agctactatt cttgcctttg
    13381 gagcctctac taaatggtca gcaatctcaa catcgcgatt aaccggtgcc gggtgcataa
    13441 taatcgcaga gtcctttaac cgcctgtagc gctcctcagt tagaccaaac tgtctatgat
    13501 aatcttcctt ggaaaagctt tgactaccat catggcgctc atgctgcacc ctaagcagca
    13561 tcaacacatc taattgatca ataatgtgat caatcgccat gtaccttcca tagctgtcaa
    13621 attcagacga gtaccattgc tcaggaccat agaaataaag ctctgctcca agccgcttta
    13681 gaatctgcat gtttgattta gccacacgag aatgtgtcaa atcccctgca atagcaatct
    13741 tcaggccatc aaaatgacca aattcttcat aaatagttag caaatcaagc aagcattgac
    13801 tagggtgctg acctgatcca tcacctccat taacgataga ggcagtaatc gttggactgt
    13861 caataagctg ctgatagtaa tcatcttctg ggtgacgaat cacgcagatt tctgttccta
    13921 gagcactcat ggtaagaaca gtatcatata aggtttcccc tttattgaca gcacttgtat
    13981 cagcgttaaa atcaaggact ctaagaccaa gcttgttctc agcaacctca aaggatttat
    14041 gggttcttgt tgaattttca aagaataaat tagctgcaaa gtgcctactg ttatctttaa
    14101 tagctacctt acctgccttg tattcagagc cacgactaat aagtcctaaa acctcttcat
    14161 ttgttaaatg ctccattgac accaaatgct taagcgcaac acgattattt acaactgaca
    14221 tgatttatcc ccttttacca ataatgaaat gatgataaca attgacaaca gctacacact
    14281 agttttctgg aagaagctga tacaatataa tgccaagaag cgttgaaaaa gcaacacccg
    14341 aaatctgaag gccattgatt tgaagcatga ggcctccaat accagaaacc agaataacac
    14401 tagcaatcaa taggtttttc ttgttgtcca tatcaacctt agcttcaatc aggattttca
    14461 agccactaga ggctataacc ccaaacagag caatcgaaat ccctccaatc actggagtag
    14521 gaatagactg aataagtgct gataccttac caacaaagct taacaaacca gcaatcacag
    14581 cggcacctgc aataacatag actgagaaga ttttattgag ggccatcaca ccaatatttt
    14641 caccataaga tgttaccgga ggcgctccta aaaatccagc aatcacctgt gcaaggccat
    14701 cacccgtcaa ggttttttcc aagccaggat ccttgaaata atctctttta gtcaggctat
    14761 taagcaccat gatatgaccg aaatgctctg tcatggtgac aaaggcaatc ggggccatcg
    14821 ttaaaatagc actaggatac aaggtaatgt cataggttaa aaaggggata gccacagctg
    14881 gaacactgag ccattgggcc ttagcaacct gtgtaaagtc aacaatagac tgacccgtca
    14941 ccataccaac aaggatcgca aacaaatagc caaccaataa gcccaacaaa ataggaatga
    15001 tggcgacaat ccctttacca taaatgttaa agaaaataat cgctaataag gtgacaagac
    15061 caatcaaaag gtataacagg ttatactttc catcctttag catgacatca ctaactgctg
    15121 ttgaggccaa gctaagaccg atcaccataa caatgggacc aaccacaact ggaggtaaga
    15181 tcttatcgat ccattcattg ccaatcgcct tcaccaccag tgctacaacc agataaacca
    15241 ggccacctgt aatcgctccc tgtgcaactg caccaatacc atctgttttc attagcattt
    15301 gcatggctgc aatataagca aagcttgagc ccatataagc gggaatttta aatgttgtta
    15361 ctgacaaatg cgccagagtc ccaagtccac ttgataagag ggcaactgac ggatcaatcc
    15421 caaccaaaat tggaaccaaa acagttgctc caaacatagc aaataaatgc tggaaggaca
    15481 agccaagcaa aatccctgcc tttggcactt cttctacatc ataaatgaca tctttcacac
    15541 aatcacctct ttcttatccc ggatcaacaa tactaatacg atcttgaccg tcaacctcaa
    15601 ccacctcaac gacaatctct tctgtcttgc ttgtgggaat attctttcca acataatcgg
    15661 cccgaattgg taattcacga tggcctcgat ccaccaaaac agctaggcta acacgtccag
    15721 gacgccctaa gctaaccaaa ttgtcgatag ctgcccgaat cgttctgccg gtataaagca
    15781 cgtcatctac taagataata tccttgccgg taatatctac cggcatgctg gtggtgtcct
    15841 cttccactct catatcatct ctaaagggct tggtatctag ctctccaact gccaagtgca
    15901 ggctttctag ctgctctaat ctttcttgaa tacgacgagc aaggtaaaca cctcttgttt
    15961 taatccctac aagcaccaca ttgtctagtt gcttgttgcg ctcaataatc tcgtacgtaa
    16021 tccgcgtgat cgcacgcttc atggttagct catcaacaat tacctttgat ttcattcaaa
    16081 gcctcctcaa aaaattcaac taaaaaaatc tccctgttaa caaggagatt cagcaaaaca
    16141 ggcacacagc tagacataac tgtgcacttt tttattcaga acatgctcct tgccagcctc
    16201 acaggactgt tttaaaggaa tattttattt tcattagtat agcaaaatca caagccaaaa
    16261 acaaggattt tctaaaaaat aattcaaaat atatagagct atcacagcac caaggaaaat
    16321 gctactaagg tcatcagcaa tcctccaaca caattccaaa aataggtctt aagacctatt
    16381 gtatttgtat caaaacaata gcacaataat atcaaacaca aaggagagcg tttatgatga
    16441 atgatataac tagaaagatt aaccataagc aactgattca aatcactacc attctaggca
    16501 ttattgttac catcgttatt ttgttctatc tgcagcagca ccctaatctt tttgcagttg
    16561 gcggtccttt tcagacctat cttatggaac ttggtatcct agcaccctgt ttgtttatac
    16621 tgcttcaaat cattcaagtg gtttacccta tcattcctgg aggcttgacc tgtgttttag
    16681 ggcatgtagt ctttgggccg ttttggggat ttctttataa tactctaggt atttttattg
    16741 gttcgctgct tagctttatg ctcgctagaa aatatggtga acagtttgct aaagcctttg
    16801 tatcagatga tacctataac aaatacattc cttacctcaa taaaggcaag tactttgaac
    16861 gatttctcat aacagccttt attctccctg gctttccaga tgattttctc tgtatggtag
    16921 ctggactaag cagcatgtct atcaaaacat ttaccagtat tttcttgata tcaaagccaa
    16981 ttactcttta tatctacacc cttcttgctt accaaggcat acaaatcgtt ggacaggtat
    17041 tgcaatccta aaaaaagcta gtattaagct atcaagcctg attggaatac agtattccaa
    17101 tcaaaaaggc gctcagcttg gtaccagctt tttatccttg tcttagttgc tccaaagtcc
    17161 tttggaagat ttctggtggc tcaacagtaa agaccagctc ctctcctgtc acagggtggg
    17221 ttagtcccaa tgtttgcgca tgaagaaact gccccttgcc agccaaggtc ttacgaggac
    17281 cgtagagtgg atctcctgca agagggtgac caatataagc catatgaacg cgaatttgat
    17341 gcgttcgacc tgtttccaat tgtaattcca cgaaggtata gtggccaaag cgctccaaaa
    17401 ccttaaaaag agtcaaggct tccttgccct tagcagttac ggtctgtttt ttacgatcct
    17461 tttcactgcg gccaatcgga gcttcaatta cacctcgatc ctttggtaaa ttaccatgaa
    17521 caatggccac atactttcgt aaggatttct tagccttgag ctcatcagct agtagctggt
    17581 gggccttatc ggtcttggca accattaaaa gaccagaggt atccttatca attctatgca
    17641 caattcctgg acgaataaca ccattaatag aagacaggtc tttgatatga tagagcaagg
    17701 cattgaccag cgtccctgta gaatgccccg cagaagggtg aacaaccatt ccctgaggct
    17761 tattaataat ggccaataca tcatcttggt agacaatatc tagtggtata tcctgagcct
    17821 gatagtccaa gctgctttcc tctgggatat gatagctaat gcagtcaccc acctgcacaa
    17881 tatacttggc cttcttaggt aagccattga ccaataccct tttttgcttg atctgatcat
    17941 tagcctgact tcttgataat ggggtcaaat cagccaaggc cttatccaag cgatggcctg
    18001 attctgttat cttaatttcc atagtcctct tctttccata gacaaatgac cagcagcaaa
    18061 acacctatcg tcaaatagga atctgccaca ttaaaaatag caaaattgat cacatctaaa
    18121 tgaatcatat caaccacata ggataacctc aagcggtcaa taaaattccc aagacctcca
    18181 gatataatca gcaataaaga gagctgtagc caaaagctag cctttgggtg cttcaacaca
    18241 taataaatgg catagccaac caccaaaaca gttatgattg taaagaacca ctgctgattc
    18301 tgtagtatgg aaaaagcagc tcctcgattt tgaagatagg tcaagctcac caaacctggt
    18361 ataaagggct tcacctgccc tagctcaata tgtgtaacag tccaccattt acttagctga
    18421 tccagtatca ttaagacaat ggcagccata ataaaactaa ttcttttcaa ctaatcctat
    18481 tcctttcagc ttaaaaacaa gagattacct tgatggcttc aaaaaagcaa caacagccag
    18541 ctgtctctgt agcgtactca accttaaagc ctccaaaaac tggtattcta gtaacctttt
    18601 agtatcattg atagtcaacc acacagcagc tctagacttg actttatatc aacaagtctc
    18661 accacagcag ctcgcttaat ccttatccat accagagcta agtcccattg tctatagctt
    18721 gcttttcttt tcgatgttca aaataatcct gtaaaatggt cacaaaatgt aaagccgcag
    18781 cagataggtt cttatcccta cgcttgacat aaatcatttt atgctccata tgatcacgca
    18841 agggaataac cttgatgcca ttaacgcttt gctgatctaa aaatccagac cctgttgcaa
    18901 aggcagctgt cctttccaaa atgccattta aggttgccct atctgacaca gtgtatatgt
    18961 gaggactctt gcttgtgtca ataaaatttt ctgaataata aagatattct tctttttctt
    19021 gagtaaagcg taccgctggc agcccttgca aatcctctaa gaaaagggct ttcctttgag
    19081 ccaatggatg gttttttgat aggtaaatat gggttgtaaa ggatagcaat tcaacataat
    19141 ccaaagccag cttatccatt cgctgaaaaa gcccctgacg gttttgtgca ttaagataga
    19201 taattccaag ctcactattt ccctgtgcca cctcatctaa aatttgcata gtcgttgact
    19261 caaaaactct aaaaacctta tgcccagcat gcttttggga aaatgctgtt attaaagctg
    19321 gtaaaaaatc ataatgctga ctcgcaattg aaaattcatt tggctccaaa gccgattgag
    19381 aaaactcctt ttccagcgag tcaaagcact taacaacctc taaggccttt tcataaaata
    19441 aaagcccctg gctggttaac acagttcctg ctgttgtcct acgaaagatc tgaaagccaa
    19501 gctctgtctc caaatccttc actgaaacag acaaactggg ttgactgaca aatagctttg
    19561 aagcagcctc acgaaaggta ccattatttg caatagcaac cacatatcgt aattgttgaa
    19621 tattcattaa tccacttcct aaatctagta cccttcatta taccataaag ccagccaatg
    19681 aaaaataaag gcgtccatct taaccatgcc aaacgtatct acagataatc atgagatagc
    19741 attgactttt tcaatagtgt cttatcatat ttagctatag aaaacagcct tactataagt
    19801 tatacttttg aaagaagtaa gccttagatc acagaacatc acactgagat tttttatgcg
    19861 cttatcctgt ctgtccaaga actgagaatt ggctacatct agctaataag ccatttcagg
    19921 attttactgt ctaggagtta tttataggca actattacag taagatagtg tcacaataca
    19981 aaaaaggcta tcccaaagta cagaacagcc ttataccgtg cccttttaac acattatttt
    20041 gcgattgggt atacagaaac ttgtttctta tcgcgtccct tacgctcaaa gcgtacaaca
    20101 ccttcaacct tagcaaaaag agtatcatct ccgccacgac caacgttaac accaggataa
    20161 atatgtgtgc cgcgttgacg gtaaaggatt gaacctcctg aaactgtttg tccatcagct
    20221 gccttagcgc caagacgttt tgcttgtgaa tcacgtccgt tagaagttga acctccacct
    20281 tttttgtggg cgaagtgttg taggttagaa agattaagtt taatcatttt tatttcctct
    20341 cgttgaattt aattcatcac aggcttttga acatattctg ataaatgctc tgccaaattc
    20401 tccaagccaa tcacaacaga ctcaaacaga atttgccaca cctgctcttg ttgctcagta
    20461 aatccctcag gctttgttac ccttaggaat ccaccaccat cgaccatttc tagtgctggc
    20521 tcaagacctg tcatctgttc aactgaatta acaagattga aggccaaaac tgaaaccgaa
    20581 gcacaaacta catcaaagcc gtactcaccg cttccagcat gtcctgtgat aagcatctca
    20641 gtccagccag ctgcgtcttt tgttaaccgt actttaatca tgtcaaacta gaattatgcc
    20701 ttgatagcgt taatcacaac tttagtgtaa ggctgacgat gaccttgctt acggtggcta
    20761 ccttttttag gcttgtactt aaaggttaca accttctttt gttttccttg cttttcaaca
    20821 gttccaacga cagtagctcc ctcaacaact ggagtaccaa cgacagtctt atcaccacct
    20881 acgagaacaa cctcgttaaa agtgatttct gcgccagctt cagcgtcaat tttctcaacg
    20941 tagattgctt gacctacttc aactttaacc tgttttccac cagttttgat gattgcatat
    21001 gtgctcatga tgcacctcct ataagatttt tgatgaggtt tccctctgtg aagactcgcc
    21061 tagaatcgtg agagccaatc tacttgaaaa cgattttcgt gcggttgcac aggacgtgca
    21121 cttagtcaac gttacaattt taacatcaaa tttgattttt atcaagaaaa atatgctttt
    21181 atcttcctaa aatcttaagc tatacataat cacagctatg taaaggctag caatgcttta
    21241 ccattttagg ttaaccaggg cattcatttc tttataagca atagctgctt tttcttgcgt
    21301 ttcgggatca atcttatcat aatatctgcc gcctttgata aagtcctcca aaaccatggt
    21361 acgatagcta tatagctcat agccttcact accataaagg cccttaggct tagctaaaac
    21421 cattgtcggg tgagccttta ctgtttttat ttttgttttt tgccccttct tctcaaaggt
    21481 aaggtccatt agcacgccgc gctctgtcca aatatcatca acagtctcta ggcgttgatt
    21541 ggaaatgaaa ttacccattg aatagataat aaatttcttt tccttgtcct taacaatcgt
    21601 ctctgccggc tctacgacgt gggggtgacc tcctaagaca acatcagcac cccagtcaat
    21661 catttttcga taaagagttt tttgctcagc tgttggctct aaagcatact ctgtgcccat
    21721 ctgcggcata acaatggtaa tatcggcctc tttttcagca cgcaagatgt ctttttgtat
    21781 cttttcctca ttaaggtcag acaggtgctt gtcatactcc tcctgactga gtgtcgcctc
    21841 cattccatta tagccatatg aatagcccaa tattgcaatc ttaatcccat taaccttttt
    21901 aatgagaatg ttctccttag agcgatcctg ctcataaata ccaatgctgt ctatccccat
    21961 atcagcaaaa acacgcttgg tattgagagc tccttctaat cttgagtcca aaatatggtt
    22021 atgggccaaa tcaaccacat catagccagt atgcttaagc gcagcagcaa tagcctctgg
    22081 cgcattaaac aaaggatagc cagctagagg atagtctgga ctgatcgttc cctcatagtc
    22141 tccaatggcc aaatcagcct gactaatcca atccttcaca tactcaaaat agggattaaa
    22201 atcatagcta ccatcagcct ttttagcact catatagaga atatcatgaa tcaaaatatc
    22261 accatttgcg acaacacgcg ctgtttgtgt cttttgaggt gtcttgcttt tcgtttgtgt
    22321 gccttttttt gacatgccta ataaatcaaa ggccaaccca aaaacaagta tcaccacaat
    22381 caaggtaagc actgaaagca tggtcttttt atactgaaaa tcttttagca agcgtcaaac
    22441 ctcctttttt cctattatac catgttgaca cgacttttta ataacaaatc ccaaagaaaa
    22501 ggctatgccc atttaagaag aatgccttag acagcagcat agactcgtat tagctagtca
    22561 aaaaactaga ttgctcctct ttggttgatg tcatatactt tgagcctaaa tagctttcaa
    22621 caaagtctaa tagttgaata atgtcatgca aaatatggta taatgaaaca aaatcaaact
    22681 agtcaggata gtcacatgaa gcataactct ttcagccgct cactattact cccccttctc
    22741 atctgttcct tgtctgcttg ctcttctcat acagagaaaa aagaccatac caaagacgct
    22801 actgctatca ccgatacccg aaaagcagag catcaggaca tcagggcaaa tatggaaaag
    22861 gtcaagctcg ctaccgctag caccgacttc aaaggtggct caagccttga ggagctaatc
    22921 actatttttg gacagcctag tcagcacgaa gaaaaagcag ctggtagtgt tactcttgac
    22981 tcctacacat ggcagtttga ccatgtcacg gttaatatta acctctatga aaacagcagc
    23041 attgttaaaa ctattgctaa ctttgctttt attagagacc tgaccttatc cttaaaggac
    23101 tacaacagct tgaaaaaggg catgacctat gatgaggtca agcagctatt gactgagcct
    23161 gataattaca gtcaagccaa ttccagtgaa aaagaaacca ttcaagccat ttggattagt
    23221 ggcttaaaag ctcagacaca gggtgccaat atagcactaa cctttgaaaa caaccagttg
    23281 acagaaatgt cacaggttgg tcttgaagac tagtttgtgg ataaccccaa tcatattaat
    23341 gatagaaaaa agcttgatat ttaataagat caagctcaaa cgatagacca agtagctgat
    23401 gatcttgaca gtaatgtgta acaagctgag atactactca ctaggcagta tttactagca
    23461 gccactgaat ttcctttatg atgacaggca accacctttt ttgtggtgac ctatcaatag
    23521 caccataagc tctcttttgt cacatacctt gcttaacatt attttaccag gtatgtgatg
    23581 agctttttag gttgtctgat agtataacat ctaaccccta gttgatgatg tagataaggc
    23641 aagagctgct aaggatagca ccataaataa gatccaacat agggtcatat tatatagtgc
    23701 caagaacgaa aagataaaga cacctacagg gagcgataaa gagaacagaa gacctaaaaa
    23761 gttattgctt tgggctagca tatctgatgg gagattttcc attaaaaggg cgtccagctt
    23821 gggtgtggct tttcccataa tataagctgc aaaggctaag cataaaaccc ctatgatggc
    23881 aggtaattgc agagcattag agactcctac cagcaaaaat gctatgccct gagtctgtac
    23941 tagctttgat attgaaagcc ttgaaaagta atcctttggt gttagatttc ccaacatcgc
    24001 tccgataatc gtaacggcat caacaataac taaagactgc ccataatgaa aatgaaatag
    24061 ctgatgatcc atcaaataaa aatgataaat gctattaatt gctcctccaa tagcgtttaa
    24121 ggtcaagatg gataagagta acatcacaaa agagatatga tcaatctttt taaaggtctc
    24181 tgtcatcctt gtatacatca ccttaaattg cttcattaat gaaacacctg cttcagaagc
    24241 ttcaacgaca tcatgcctta gcttttgtcg atttttaaga agcacaacag atgacaataa
    24301 aaaggaaata gcatttatca aagcaacaaa ggcataattg ttgcctgatg tcgttagcag
    24361 ccaaactcct aaagcttgtc ctgcaatact agagaggtag ccgataaatt gagcaaaaga
    24421 ataggcctca tagagctttt ctgattcaat atttttctgc attatcggga gacgtaagcc
    24481 atttttgtaa tcacttagaa tatcagaaac cacattcaaa aagcccacaa aggcaaatac
    24541 caagaacgtc tgatttgtca tcaacaaggc tacaagcgta aataaaagag attgtataaa
    24601 accaataaca ataagatttc ttgttttcct ttttgtctta tctgctttga cgccaatcca
    24661 aaaggtaaac accataggaa tgatggtgat gatattggct ataaaaacag caatatgaga
    24721 ataaggtagc gtggttgcat aaataataaa aacaatattg taaatataag agcctaaagc
    24781 acttaaaaag tttgaaactg tcagtgttct aaaaacgaca tttttaatca atcccctcat
    24841 ttacttacct gttgacgtcc tttcttatgt caccttactt tacttgattg aatatactta
    24901 cagcatatct aaattcgtac tgtagtttta tatggtgttc tgacatgatt ttgctactaa
    24961 ttagtaattc acaagccttt tctaagtata aagtatcgtt tgttagtcta aatacttgta
    25021 aaagtgtcat ggctatcccc agcattccgt tccatagacc actaaactga gcaaattcaa
    25081 ctaataacga ctccgataaa ttcttaatat ctttaatata tttatcggag ttaacgtaaa
    25141 taagcaattg aacgatccca gcagtcccat ttgataagta tggagataca gaattttctg
    25201 atattaatac accccgattt ccatcgctat cttcaactaa gctttctaga ataaaatcaa
    25261 ttcctttctc aataatttcg ttatcataag aaattgaaga cagatagaac aatactccag
    25321 ctaaaccatt taaccctaaa ttaacttctg attttaattg catcaaaact tcatcg
//
LOCUS       DARYXW010000021        24305 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.021, whole genome shotgun sequence.
ACCESSION   DARYXW010000021 DARYXW010000000
VERSION     DARYXW010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24305
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.021"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            152..1756
                     /locus_tag="TV191_000701"
     CDS             152..1756
                     /locus_tag="TV191_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_156117153.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEL1507236.1"
                     /translation="MFLRNNKQKFSIRKLSAGAASVLVATSVLGGTTVKANSEVSRTA
                     TPRLSRDLKNRLNDIAISRDASSAQKVRNLLKGASVGDLQALLRGLDSARAAYGKDDY
                     YNLLMHLPSMLNDKPDGDRRQLSLASLLVDEIEKRIADGDSYAKLLEAKLAVIKSQQE
                     MLRERDSQLRNLEKEKEQELQKAKDERQALTESFNKTLSRSTKEYNKLKTELAKEKEK
                     AAKMTKELADKLSNAEASRDKAFAVSKDLADKLSSAEASRDKAFAVSKDLADKLAAKT
                     AEAEKLMENVGSLDRLVESAKREMAQKLAEIDQLTADKAKADAELAAANDTIASLQTE
                     LEKAKTELAVSERLIESGKREIAELQKQKDASDKALVESQANVAELEKQKAASDAKVA
                     ELEKEVEAAKAEVADLKAQLAKKEEELEAVKKEKEALEAKIEELKKAHAEELSKLKEM
                     LEKKDHANADLQAEINRLKQELADRIKSLSQGGRASQTNPGTTTAKAGQLPSTGESAN
                     PFFTIAALTVIAGAGMAVVSPKRKEN"
     gene            1979..4198
                     /locus_tag="TV191_000702"
     CDS             1979..4198
                     /locus_tag="TV191_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEL1507237.1"
                     /translation="MVKEINLSGEEVVALAAKYMTDGDVELVQKALDYATAAHFYQVR
                     KSGEPYIVHPIQVAAILADLHLDAVTVVCGFLHDVVEDTDITLEDIEFDFGKDVRDIV
                     DGVTKLGKVEYKSHEEQLAENHRKMLMAMSKDIRVILVKLADRLHNMRTLKHLRKDKQ
                     ERISRETMEIYAPLAHRLGISRIKWELEDLAFRYLNEIEFYKISHMMREKRREREALV
                     DDIVTKIKAYTTDQGLYGDVYGRPKHIYSVYRKMRDKKKRFDQIFDLIAIRCVMETQS
                     DVYAMVGYIHELWRPMPGRFKDYIAAPKTNGYQSIHTTVYGPKGPIEIQIRTKEMHQV
                     AEYGVAAHWAYKKGIRGKVNQVEQKVGMNWIKELVELQAASNGDAKGFVDSVKEDIFS
                     ERIYVFTPTGAVQELPKDSGPIDFAYAVHTQVGEKATGAKVNGRMVPLTAKLKTGDVV
                     EIVTNPNSFGPSRDWIKLVKTNKARNKIRQFFKNQDKELSINKGRELLVSYFQEQGYV
                     ANKYLERKRIEEILPKVSVKSEESLYAAVGFGDISPVSVFNKLTERERREEERAKAKA
                     EAEELVKGGEVKHENKEILKVRSENGVIIQGASGLLMRIAKCCNPVPGDVIEGYITKG
                     RGIAIHRADCNNIKSQDGYQERLIEVEWDLEHSSKDYQAEIDIYGLNRIGLLNDVLQI
                     LSNATKSISTVNAQPTKDMKFANIHVSFGIPNLAQLTAVVEKVKAVPDVYSVKRTNG"
     gene            4213..4656
                     /locus_tag="TV191_000703"
     CDS             4213..4656
                     /locus_tag="TV191_000703"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEL1507238.1"
                     /translation="MKIVIQRVKEASVSIDGKIAGAIDQGLLLLVGIGPDDQAEDIDY
                     AVRKISHMRIFSDPEGKMNRSIQDIEGSVLSISQFTLYADTKKGNRPAFTGAAKPDRA
                     SQLYNSFNAQLEQLVPVQRGVFGADMQVSLINDGPVTIILDTKYR"
     gene            complement(4783..6075)
                     /locus_tag="TV191_000704"
     CDS             complement(4783..6075)
                     /locus_tag="TV191_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HEL1507239.1"
                     /translation="MLTSKRLYHLGKTPLEIGTVVIGLFTMTLGAPAVKANHYKVGWA
                     WSSSSRVANHYKYEDTTKPIHSKDYQETTGLYLMVNITGVDNTNHTIVSPHYQDIRLE
                     YGKTYTTNEMIKLVQDVIDPSAESFKVISLKNAKLTKASTAEILSTDHFTTPIKGQYH
                     QKDQTYILTGQVLVEKVSKVALKDIKVTDKAGNPIQDSDAVAVTQHVKFLKKDNGQLV
                     NVDVTDSLGKEGLTGLRYYGSRVSSEELFEAAKKAFETTQAFKDGYQLVKRISTTVTQ
                     DPDITHQSHNGEIYSGASERMVYHADRDEDFNYIIDSNRIAQVYNSKYDVNNPISYAT
                     HSDSVVETYFISKDINDDYSTTYRSVTIYQQDKQQQLINEYTFKTHEAITTETIDKYL
                     KGLPNTFQAKNGTSYQFTGSLTPISETEFIAVYKDLQK"
     gene            6830..7678
                     /locus_tag="TV191_000705"
     CDS             6830..7678
                     /locus_tag="TV191_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEL1507240.1"
                     /translation="MALKDYFPDMQEGAFPLADQDWISVEVGEQYLHFPKSSLSEREQ
                     LLLGLGRQRKEPSKDQKSPWYHYLILGQGEQPEEFQGCQFIYINHQCPLAGDLIELLK
                     GIIEGVEAVLPISQTRTAFLVCHHSRSDLFQLLANLLPTIESDFGLALMIFIGNGWYQ
                     VSGNALRDYFKEENAVFTAYLAEHSASRLLTFSEVMLWSLLANSGLPALSKHFSQLLL
                     ANKEVMDLVLAMWQEHGNLVQTAQRLYIHRNSLQYKLDKFAQQSGLYLKQLDDLAFAY
                     LFILKH"
     gene            7828..8961
                     /gene="ugpC"
                     /locus_tag="TV191_000706"
     CDS             7828..8961
                     /gene="ugpC"
                     /locus_tag="TV191_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEL1507241.1"
                     /translation="MVELNLKHIYKKYPNTTHYAVEDFDLDIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELKIDGEVVNDKSPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYKKDDIDRRVKEAAEILGLTEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGSTTIYVTHDQTEAMTLADRIVIMSATKNPQGN
                     GTIGKIEQVGSPQELYNLPANKFVAGFIGSPAMNFFEVVVKDGQIISEDGLDIAIPEG
                     QAKMLEAAGYKGKKVIFGIRPEDISSNQIVHDTYPNANVTAEVLVSELLGSETMLYVK
                     LGQTEFASRVDARDFHNPGEKVSLTFNVAKGHFFDLETEQAIR"
     gene            9145..10764
                     /locus_tag="TV191_000707"
     CDS             9145..10764
                     /locus_tag="TV191_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEL1507242.1"
                     /translation="MEKHWWHKATIYQIYPRSFMDTSGNGIGDLKGITGKLDYLQELG
                     ITAIWLSPVYQSPMDDNGYDISDYQAIAAIFGDMADMDELLDEAKQRGIKIIMDLVVN
                     HTSDEHAWFVEARENPDSPKRDYYIWRDQPNNLMSIFSGSAWEYDDASGQYYLHIFSK
                     KQPDLNWENAELRQSIYDMMNFWIDKGIGGFRMDVIDLIGKIPDSEITGNGPRLHEYL
                     KEMNQASFGNHDLMTVGETWGATPEIARQYSRPENKELSMVFQFEHIGLQHKPNASKW
                     DYAAELNVPALKEIFSKWQTELKLGEGWNSLFWNNHDLPRVVSIWGNDTVYREKSAKA
                     MAILLHLMRGTPYIYQGEEIGMTNYPFERLSDVNDIESLNYAKEAMANGMSEEAVLDC
                     ICRVGRDNARTPMQWSSQKNAGFSTADQTWLPVNPNHQEINVASALADPDSVFYTYQK
                     LIQLRQTQDWLVEADYQLLETSDKVFAYKRQLGRETYLVVVNLSNQEQFFEESLHKAQ
                     VIISNTDVQAVVESQQLEPWDAFCVKLDETL"
     gene            10873..11235
                     /gene="traF"
                     /locus_tag="TV191_000708"
                     /pseudo
     CDS             10873..11235
                     /gene="traF"
                     /locus_tag="TV191_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623564.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraF"
     gene            11349..11708
                     /gene="yajC"
                     /locus_tag="TV191_000709"
     CDS             11349..11708
                     /gene="yajC"
                     /locus_tag="TV191_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEL1507243.1"
                     /translation="MGLPTILMFVVMIGLIWFMQRQQKKQAQERQNQLNAIEKGDEIV
                     TIGGMFAVVDEVDLAAKRIVLDVDGVYLPFELSAIKRVVEKGSAVTSADVDTTETAVD
                     DTAVEASDEAESAIETN"
     gene            11882..12631
                     /locus_tag="TV191_000710"
     CDS             11882..12631
                     /locus_tag="TV191_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEL1507244.1"
                     /translation="MFGLKAKSKKIVLDRIPKHIGIIMDGNGRWAKKRLKPRVFGHKA
                     GMDALQEVTIAASDLGVKVLTVYAFSTENWSRPQDEVSFIMNLPVEFFDKYVPELHKN
                     NVKVQMIGETNRLPKDTLKALEAAIAKTRQNTGLILNFALNYGGRAEITNAVGLIAQD
                     VLDAKLNPGDITEDLIANYLMTDHLPYLYRDPDLIIRTSGELRLSNFMPWQSAYSELY
                     FTPVLWPDFKRAELLKAIEDYNHRHRRFGAI"
     gene            12641..13435
                     /locus_tag="TV191_000711"
     CDS             12641..13435
                     /locus_tag="TV191_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEL1507245.1"
                     /translation="MRERFIWGGVAAAVFLPFLLIGSLPFQLFVGVLAMIGVSELLRM
                     KRLEVFSFEGVFAMLAAFVLTVPLDHYLTFLPMDASFACYGLLVFFLLAGIVISSDSY
                     GFEDASFPIAASLYVGIGFHNLVNARMTGIDKVFLALFIVWATDIGAYLIGRRFGKRK
                     LLPKISPNKTIEGSLGGIVSAVLVSFVFMLFDKAVYAPHHFGTMLILVALFSIFAQFG
                     DLVESAVKRHFGVKDSGKLIPGHGGILDRFDSMIFVFPIMHLFGLF"
     gene            13467..14732
                     /gene="rseP"
                     /locus_tag="TV191_000712"
     CDS             13467..14732
                     /gene="rseP"
                     /locus_tag="TV191_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEL1507246.1"
                     /translation="MLGIITFIIIFGILVLVHEFGHFYFAKRSGILVREFAIGMGPKL
                     FSHVDQQGTLYTIRLLPLGGYVRMAGWGDDTTEIKTGTPASLTLNDQGLVKRINLSQS
                     KLDPTSLPMNVTAYDLEDKLTITGLVLDEIKTYSVDHDATIVEEDGTEIRIAPLDVQY
                     QNASIGGRLITNFAGPMNNFILGIVVFILFAFVQGGVADYHSNHIRVVENGAAAKAGI
                     RDNDQILEINHQKINDWYELTQAVTDSAADVKAKGKLEITYQTGDQVKTIALKPEKKG
                     DQYLIGVQYPLKTSLTDKLIGGFEMAGNGALVIVTALKSLITSFSLDKLGGPVAMYQM
                     SNQAAKNGLESVLSLMAMLSINLGIFNLIPIPALDGGKILMNVIEALRRKPLKQETET
                     YITLAGVAIMVVLMIAVTWNDIMRAFFQG"
     gene            15002..16858
                     /locus_tag="TV191_000713"
     CDS             15002..16858
                     /locus_tag="TV191_000713"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEL1507247.1"
                     /translation="MKQSKMLIPTLREMPSDAQVISHALMVRAGYVRQVSAGIYAYLP
                     LAHRTIEKFKTIMRQEFDKIGAVEMLAPALLTADLWRESGRYETYGEDLYKLKNRDKS
                     DFILGPTHEETFTTLVRDAVKSYKQLPLNLYQIQSKYRDEKRPRNGLLRTREFIMKDG
                     YSFHQSYDDLDVTYDAYRQAYEAIFTRAGLDFKGIIGDGGAMGGKDSQEFMAITPDRT
                     NLDRWLVLDKSIPSLADIPEEVLEEIKAELASWLVSGEDTIAYSSESSYAANLEMATS
                     EYKSSSKVTALDDLVEIETPNCKTIDEVAAFLDVAEHQVIKTLLFMVDHEPVLALLVG
                     NDQINAVKLKNHLGADFLEPASEEEARAILGAGFGSLGPVHLTDGIRIVADRKVQDLA
                     NAVAGANKDGYHLTGVNPNRDFQAEYADIREVKEGETSPDRHGVLQFARGIEIGHIFK
                     LGTRYSDSMAANILDENGRAVPIVMGCYGIGVSRILSAVIEQHARLFVSKTPKGDYRY
                     AWGINFPKELAPFDVHLITVNVKDQEAQDLTERVEASLMAKGYDVLTDDRNERVGSKF
                     SDSDLIGLPIRVTIGKKAAEGIVEIKIKATGDSIEVHADSLIETLDILTKDN"
     gene            16910..17467
                     /locus_tag="TV191_000714"
     CDS             16910..17467
                     /locus_tag="TV191_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEL1507248.1"
                     /translation="MTIEELQQLVLADHELMTILSIIETLPLKDCWLAAGAIRNAIWN
                     HLAYGIGFDPLTDVDVVFFDPEISYEAEQLLEEQLKCAYPMYQWEVRNQAYMAAHNPK
                     TPPYRSSQDAITKYPERCTAIAVRLVGGQLEVFAPYGLADISHFVCRPTPHFLEDSER
                     MDCYRQRLAKKDWHKKWPQLTYHDC"
     gene            17802..22199
                     /locus_tag="TV191_000715"
     CDS             17802..22199
                     /locus_tag="TV191_000715"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEL1507249.1"
                     /translation="MSDLFGKLMEQIEMPLEIRQSSAFSSADIIEVKVHSVSRLWEFH
                     FSFAEVLPIESYRELSDRLVRTFEAADIKVTFDIKAETINYSDQLLQAYYQEAFEHEP
                     CNGASFKSSFSRLQVRYDHHQLIIMAPDFVNNDHFRKNHLPNLAAQFERFGFGRLAID
                     MVSDQEMTDHLTKDFETNRQALVEKAVQDNIAAQQSLEAMQPPAEEAAPSPSLDYRER
                     MAQRQASFDKAVITPMIEVDTEENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSF
                     AMQKWAKDDDELRKFDLIAKGAWLRVQGNIENNPFTKSLTMNVQQVKAIVHHERKDLM
                     PEGQKRVEFHAHTNMSTMDALPTVEDLIDTAARWGHQAVAITDHANVQSFPHGYHRAR
                     KAGIKAIFGLEANIVEDKVPISFNPVAMDLHEATYVVFDVETTGLSAMNNDLIQIAAS
                     KMFKGNIIEQFDEFINPGHPLSAFTTELTGITDNHLVGAKPIQQVLEAFQAFCQGTIL
                     VAHNASFDVGFMNANYDRYGLAKISQPVIDTLELARNLYPEYKRHGLGPLTKRFQVSL
                     EHHHMANYDAEATGRLLFIFLKEAREKHGITNLLQLNTDLVAEDSYKKARIKHATIYV
                     QNQLGLKNMFKLVSLSNVKYFEGVPRIPRTVLDQHREGLLLGTACSDGEVFDAVLTQG
                     IDAAVDLAKYYDFIEIMPPAIYQPLVVRELIKDQAGVEQIIRDLIEVGRRAEKPVLAT
                     GNVHYIEPEDAIYRDIIVRSLGQGALINRTIGRGEAAKPVPLPEAHFRTTNEMLDDFA
                     FLGQDLAYEVVVQNTQALADRIEKVEVVKDDLYTPYIDKAEETVAELTYQKAFAIYGN
                     PLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMI
                     GITEVNPMPPHYVCPSCQQSEFITDGSVGSGYDLPNKACPRCGTLYKKDGQDIPFETF
                     LGFDGDKVPDIDLNFSGDDQPNAHLDVRDIFGEEYAFRAGTVGTVAEKTAYGFVKGYE
                     RDYGKFYPDAEVDRLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQFPADDVTAS
                     WQTTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPITIPADDPDVMALFSGTE
                     VLGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVWLGNA
                     QDLIKEGIATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERSSY
                     IKAMRQNNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIR
                     AKAFELKTMSGGLAAVKARMEDISNKRKRNEASNVENDLFTTLEIVNEMLERGFKFGK
                     LDLYKSEATEFQIEGDTLIPPFIALEGLGENVARQIVKARQDGEFLSKMELRKRGGAS
                     ATLVDKMDELGILGNMPDDNQLSLFDDFF"
     gene            22321..22749
                     /locus_tag="TV191_000716"
     CDS             22321..22749
                     /locus_tag="TV191_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEL1507250.1"
                     /translation="MNELDKNPALKAMVVFRKAQRTLDAQSSAFFQKANLTPTQFSVL
                     EVLYSKGSMRINKLIGSLLATSGNMTVVLKNMERNGWISRCQDAKDKRACLVQLTPEG
                     KALIETILPEHIKRVEALFSVLTETEQKQLITLLKKFKEL"
     gene            22879..23424
                     /locus_tag="TV191_000717"
     CDS             22879..23424
                     /locus_tag="TV191_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEL1507251.1"
                     /translation="MKQILIINGSLRTGSFNHQLAQAAEQLLEGKAAVSYLDWEQVPM
                     FSQDLEASTPESVAGVREAIQAADAIWIFSPVYNFAIPGSIKNLLDWVSRALDLSDPS
                     GPSAINGKVVTVSSVANGGHEQLFAQYQDLLPFIRTTVVGNFTKAAVNPEAWATGVLD
                     ISEETRQSLAAQAEALLEAIH"
     gene            complement(23603..24217)
                     /locus_tag="TV191_000718"
     CDS             complement(23603..24217)
                     /locus_tag="TV191_000718"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEL1507252.1"
                     /translation="MSAQDKLIKAQHLIDMNDIIREGNPTLRAVAKEVEFPLSDDDII
                     LGEKMMQFLKHSQDPVMGEKLGLRAGVGLAAPQIDVSKRIIAVLVPNPEDSEGNPPKE
                     AYSMEEVLYNPKIVSHSVQDAALADGEGCLSVDRVVEGYVVRHARVTVEYYDKHNEKH
                     RIKLKGYNAIVVQHEIDHINGVLFYDRINAKNPFEAKEGMLILN"
BASE COUNT         6927 a         4785 c         5836 g         6757 t
ORIGIN      
        1 aaaaacaata atatacattc ttgcttatta aataaaaatg acaatgtact gcataaagaa
       61 gttcctgtca ttaaaataaa agtgccatga ggttataata gtatggtaaa acaaaaaagt
      121 gtgcccataa cgggtagaga ggaattgaca tatgtttttg agaaataaca agcaaaaatt
      181 tagcatcaga aaactaagtg ccggtgcagc atcagtatta gttgcaacaa gtgtgttggg
      241 agggacaact gtaaaagcga actctgaggt tagtcgtacg gcgactccaa gattatcgcg
      301 tgatttaaaa aatagattaa acgatatagc cataagtaga gatgcctcat cagcccaaaa
      361 agttcgaaat cttctaaaag gcgcctctgt tggggattta caggcattat tgagaggtct
      421 tgattcagca agggctgcgt atggtaaaga tgattattac aatttattga tgcaccttcc
      481 atcgatgtta aatgataaac ctgatgggga tagaagacaa ttaagtttgg cttcattact
      541 tgtagatgaa attgaaaagc ggattgctga tggagatagt tatgcaaaac ttcttgaggc
      601 taaacttgca gttattaaat ctcaacaaga aatgcttaga gaaagagatt cccaacttcg
      661 aaatctagag aaggaaaaag aacaagaact acaaaaagct aaagatgagc gtcaagctct
      721 taccgaatca ttcaacaaaa ctttatcaag atcaacaaaa gagtataata aactaaaaac
      781 agaacttgca aaagaaaaag aaaaagcagc taagatgact aaggaattag cagataagct
      841 aagcaatgct gaagcaagtc gtgataaagc ctttgcagta tcaaaagatt tagcagataa
      901 actaagtagt gctgaagcaa gtcgtgataa agcttttgca gtatcaaaag atttagcaga
      961 taaattggca gctaaaacag cagaagctga aaagttaatg gaaaacgttg gtagtctaga
     1021 ccgcttggta gagtctgcaa aacgtgaaat ggctcaaaaa ttagcagaaa ttgatcaatt
     1081 aactgctgat aaggctaagg ctgatgcaga gcttgcagct gcaaatgaca ccattgcatc
     1141 acttcaaaca gagctagaaa aagctaagac agagcttgct gtttcagagc gtttgattga
     1201 atcaggcaaa cgtgaaattg ctgagctaca aaaacaaaaa gatgcttctg ataaggcttt
     1261 agtagaatca caagctaatg tagcagagct tgaaaaacaa aaagcagcat cagatgctaa
     1321 ggtagcagag cttgaaaaag aagttgaagc tgctaaagct gaggttgcag atcttaaagc
     1381 acaattagct aagaaagaag aagagcttga agccgttaag aaggaaaaag aagcgcttga
     1441 agctaagatt gaagagctca aaaaagctca tgctgaggaa ctttcaaaac ttaaagaaat
     1501 gcttgagaag aaagaccatg caaatgcaga tcttcaagca gaaatcaatc gcttgaagca
     1561 agagctagct gacaggatta agtcattgtc acaaggtggt cgtgcttcac aaacaaaccc
     1621 aggcactaca actgctaaag caggtcaatt gccatctact ggtgagtctg ctaacccatt
     1681 cttcactatt gcagctctta ctgtcatcgc tggtgctggt atggctgtgg tgtctcctaa
     1741 acgcaaagaa aactaagcta tttcctcttt ccccaatgga caatagccga aataatagag
     1801 cgactatcgt tctaacacaa aagcaacagt ctcctgtctg ttgctttttg tgatattagg
     1861 gctcatcagt ctaggctaat ggttttctgc gctttatctg cagctttgag gattccttct
     1921 tttgctttta cagtgaaagt gttaaaatag gaaaaacaac tagtaattga ggaagtaaat
     1981 ggttaaagaa atcaatttat caggagagga agtagttgcc cttgctgcca agtacatgac
     2041 agacggtgac gtcgagcttg tgcaaaaggc gcttgattat gcgacagctg ctcattttta
     2101 ccaggttaga aagtcggggg agccttatat tgtgcaccct attcaggtag cagcaatcct
     2161 agcagacctg catttggacg ctgtgacagt tgtctgtggc tttttgcatg atgtggtaga
     2221 ggatactgat attactctag aggacattga gtttgacttt ggtaaggacg ttcgtgacat
     2281 tgttgatggg gtcacaaagc ttggtaaggt agaatacaag tctcacgagg agcagctggc
     2341 tgaaaaccac cgcaaaatgc tcatggccat gtcaaaggac attcgtgtga ttttggtcaa
     2401 gctagccgac cgactgcaca atatgcgcac cctcaagcac ctccgtaagg acaagcagga
     2461 gcggatttct cgtgaaacca tggaaatcta tgccccgcta gcccatcgct tggggatcag
     2521 tcggatcaag tgggagctgg aggatctagc ttttcgctac ctcaatgaga tcgaattcta
     2581 caaaatctct catatgatga gagaaaagcg gcgggagcgc gaagctttgg ttgatgatat
     2641 tgtcactaag attaaagcct acaccaccga tcaagggctt tatggtgatg tctatggccg
     2701 tcctaagcac atctactcgg tttaccggaa aatgcgtgac aagaaaaagc gctttgatca
     2761 gatatttgac ttgattgcga tccgttgtgt catggagaca caaagtgatg tttacgcgat
     2821 ggtcggctat attcatgagc tctggcgtcc catgcctggc cgcttcaagg actacattgc
     2881 agcgcctaag accaatggct atcagtcgat tcacacgact gtttacgggc caaaaggacc
     2941 gattgaaatt cagattcgga ccaaggaaat gcatcaggtc gctgagtatg gggtagcagc
     3001 ccactgggcc tacaaaaaag gtattcgtgg caaggtcaat caagtcgagc aaaaggttgg
     3061 tatgaattgg attaaggagc ttgtcgagct tcaggctgcc tcaaatggcg atgctaaggg
     3121 ctttgttgac tcggtgaagg aggacatctt ttcagagcgt atctatgtgt tcacaccgac
     3181 aggagcagtg caggaattgc ccaaggattc aggccctata gactttgcct atgccgttca
     3241 cactcaggtt ggtgaaaagg cgacaggagc caaggtcaat ggccgcatgg tgcccttgac
     3301 agccaagtta aaaaccggtg atgtggtgga aattgtcacc aatccgaatt cctttggtcc
     3361 tagtcgtgac tggattaagc tcgtcaagac caataaggct cgtaacaaga ttcgccaatt
     3421 ctttaaaaat caggacaagg agctgtctat caataaagga cgtgagcttc tggttagtta
     3481 ttttcaagag cagggctatg ttgccaacaa gtaccttgag cgtaagcgta ttgaggagat
     3541 tttaccaaag gtcagtgtta aaagcgagga gtctctctat gccgctgttg gctttggcga
     3601 tattagccca gtcagtgtct ttaataaatt aaccgaaaga gaaaggcgtg aggaggagcg
     3661 tgccaaggct aaggctgaag ctgaggagct ggttaagggc ggtgaggtca agcatgaaaa
     3721 caaagagatt ctcaaggtcc gcagtgaaaa tggcgtgatt atccaagggg cgtctgggct
     3781 tctcatgcgt atcgccaaat gctgcaatcc cgtaccagga gatgtgattg aaggctatat
     3841 taccaaggga cgaggcattg ctattcaccg cgcagactgt aataacatca agagtcagga
     3901 cggctatcag gagcgtctca ttgaggttga gtgggatttg gagcattcta gcaaggatta
     3961 ccaagctgag attgatattt atggtttaaa tcgtatcggc ctgctcaatg atgtcctgca
     4021 aatcctatct aacgccacca agagcatttc aactgtcaat gcccagccga ccaaggacat
     4081 gaagtttgcc aatattcatg tgagctttgg cattcctaat ctggctcagc tgacagctgt
     4141 tgttgaaaag gtcaaggcgg ttccagatgt ttacagcgtc aaacgaacca acggataaaa
     4201 aggagaccaa ccatgaaaat tgtgattcag cgcgtcaagg aagcctcagt gtcgattgat
     4261 gggaaaatag ctggcgctat tgatcaaggg ctgctgctgc ttgttggcat aggtccagat
     4321 gatcaggcag aggatataga ctatgcagtg cgtaaaatca gtcatatgcg gattttttca
     4381 gaccccgagg gcaagatgaa ccgatccatt caggacattg agggcagtgt cttgtctatc
     4441 tcgcagttta cgctatatgc tgacaccaaa aagggcaacc gacctgcctt caccggggct
     4501 gctaagcctg acagggccag ccagctttat aacagcttca acgctcagct agagcagctt
     4561 gtaccggttc agcgaggggt ctttggtgcg gacatgcagg ttagtctgat caatgatggc
     4621 ccagttacga ttatcctaga tacgaagtat cgataactgc ctagcgatcg atcgtttgct
     4681 taggagagtc atataaagga aaaacaaaaa gacgagtggt atgagaagca ctcgtctttg
     4741 tcgtttatgc tgctgtgttg aagctagcta gggctactag tcttattttt gcaggtcttt
     4801 gtagactgcg atgaattctg tctcagaaat tggggttaag ctgccagtga attggtaaga
     4861 agtaccattt ttagcttgga aagtattagg taaaccttta aggtatttgt cgatagtctc
     4921 agtggtaatt gcttcgtgtg ttttaaaggt gtattcgtta atcagctgct gctgtttgtc
     4981 ctgttggtaa atagtaactg aacgataggt tgtgctatag tcatcgttaa tatccttaga
     5041 aataaaatag gtttctacaa cagaatctga atgtgtcgca tagctaatgg gattgttgac
     5101 gtcatacttt gaattatata cttgagctat cctgttagaa tctatgatat agttaaagtc
     5161 ctcatcgcga tcagcatggt agaccatgcg ttcactagct ccactgtaaa tctcaccgtt
     5221 atggctttga tgagttatat caggatcctg cgtgactgtt gtactgattc gcttgacgag
     5281 ctgatacccg tctttgaaag cctgagtggt ttcaaaagcc tttttagcag cttcaaagag
     5341 ctcctcagaa gagaccctgc tgccatagta tcttaacccg gtaagtcctt ctttaccaag
     5401 gctgtcagtt acatcaacat taacaagctg cccattgtct tttttgagga atttaacgtg
     5461 ctgtgtcaca gctacggcat ctgaatcttg gattgggttt cctgccttat ctgttacctt
     5521 aatgtccttg agagctacct tgctaacttt ttccacaagg acctgacccg tcaagatgta
     5581 tgtttggtct ttttgatgat actgtccttt gattggtgtc gtaaaatggt ctgtgctaag
     5641 tatttcagct gtagaagctt ttgttaattt ggcatttttc aaactaatga ccttaaagct
     5701 ttctgctgaa ggatctatga cgtcttgaac tagctttatc atctcatttg tggtgtaggt
     5761 tttgccatat tctagtctaa tatcctgata atgtggagat acgatggtgt gattagtgtt
     5821 atctactcca gtgatattga ccatgaggta cagtcctgtg gtttcttgat agtcttttga
     5881 atggattggc ttagtggtgt cctcgtattt atagtgattt gctaccctac tagagcttga
     5941 ccatgcccac ccaactttgt aatggtttgc tttaacggca ggtgctccca aggtcatggt
     6001 gaatagtcca atgactacag ttcctatttc taaaggtgtt ttcccaaggt gatacagtct
     6061 ttttgaagtc aacatatttc aaacctccct aaatcctgtc agtctctata gttataaaaa
     6121 tacagagaat cgttagaaga attaatgttt catgccggca agatgagtgt aacaaaagat
     6181 tggtgccgat acaagaagat ggagattaga gcatctggtt tcaatgagag ttacataata
     6241 gcagaaggtt ttttcactat gagagctaat cgtcttaaaa tggtataata gcaagtgaat
     6301 aggctatcta actggtttaa cagccatttt tagagaagct taatagtatt gctgataagt
     6361 gactcgtatc tccatattgc ttttcaaagg ctatgttagc tatgataagc gtgaccaggc
     6421 tatcggaaaa tccagtgttc ttaaaggctt tgaagctctg gctttgaacc ttagctctgg
     6481 tgtttctatg aaaatgactt gggccttgta ccagataaga atgaagtcaa attgaggttt
     6541 tttgacaaaa tgtttgagta aatacaagtt catagaagtc taatgtataa aaatacaatt
     6601 gtatcgccat aatctgaatg accaaaccat taaaaaaata aaatttttaa acattttgga
     6661 aaacgctttc aaaactaaaa agaactgtcc tatagtcatt gcttagcatt aaagcaaggt
     6721 gtgaaatgtt atcatatgga gaaataggct gtcttgtgct gtatctgtgc caaaaaagaa
     6781 tgcttgtttt tgtgatataa tgtgactaag aaacctgaaa ggaatgctta tggcattaaa
     6841 agactatttt cctgatatgc aagagggtgc atttcctctg gctgaccaag attggattag
     6901 cgttgaggtt ggggagcagt acctccattt ccccaaatcc agcttgtcag agcgagagca
     6961 gcttttgctt ggtttggggc ggcagcgcaa agagccgtcc aaggatcaga aatctccttg
     7021 gtatcattat ttgattctgg gccaagggga gcagccggag gagtttcagg gttgccagtt
     7081 catctatatc aaccatcaat gtcctttagc aggtgatttg attgagcttc taaaggggat
     7141 catagaggga gttgaggctg ttttgcccat tagccagacc aggacagctt ttttggtctg
     7201 tcaccatagc cgttcagacc tttttcagct cttagcaaat ttattgccca cgattgagag
     7261 cgattttggt ttggccttga tgatttttat cggtaatggc tggtatcagg tgtcaggaaa
     7321 tgccttgaga gactatttta aggaagaaaa tgctgtgttt acagcttatc ttgctgagca
     7381 ctctgccagt cgcttgctga ccttttcaga ggtcatgctc tggtcactct tagcaaacag
     7441 tggtttgcca gccttgtcaa agcattttag tcagctgctt ttagccaata aagaggtcat
     7501 ggatctggtg ctcgccatgt ggcaggagca tggcaacctg gtacagacag cccagcgctt
     7561 gtatattcat cgcaattcgc tgcaatataa gctggataag tttgctcagc agtcaggtct
     7621 ctatttaaag cagctagatg acttggcctt tgcttatcta tttatactga agcattagat
     7681 ttgtgcaggg tgcccaaaga catttgggcg ttttgtctat atgatgaaaa cgctatcttt
     7741 gctataataa aagcatcaaa taaaaagtgt cagggttgct agcattgcag tcagctagca
     7801 gcctatctga cccattagga gtaacgcatg gttgaattaa acttaaagca catctataag
     7861 aaatacccaa ataccacaca ctatgctgtt gaggatttcg atttagacat taaggataag
     7921 gaatttatcg tttttgtagg gccttcaggc tgtggtaagt caacaacgct tcgtatgatt
     7981 gctgggcttg aggatatttc agagggtgaa ttgaaaattg acggtgaggt tgtgaatgac
     8041 aaatcaccaa aggaccgcga tatcgcgatg gttttccaaa actatgccct ttacccgcat
     8101 atgaccgttt atgacaacat ggcctttggt ctcaagctac gtaaatacaa aaaagatgat
     8161 attgatcgtc gtgtcaagga agcagcagaa atccttggct tgacagaatt tttagaacgt
     8221 aagccagcag acctttctgg tggtcagcgt cagcgtgtgg ctatgggacg tgctatcgtg
     8281 cgtgatgcca aggtattctt gatggacgag cctttgtcaa acctagacgc taagctgcgg
     8341 gtgtcaatgc gtgctgaaat tgcgaaaatt caccgccgta tcggctcaac aacaatctac
     8401 gtaacgcacg accagaccga agcgatgacc ttggcagatc gtatcgttat catgagtgcc
     8461 actaaaaacc ctcaaggcaa cggtacaatc ggaaagattg agcaggttgg ctcaccacag
     8521 gagctctata acctaccggc caataaattt gttgcaggct ttattggaag ccctgcgatg
     8581 aacttctttg aggtggttgt caaggacggt cagatcatca gtgaggacgg gcttgatatt
     8641 gctattccag aaggtcaggc taaaatgctt gaagcagctg gctataaggg caagaaggtt
     8701 atttttggta tccgtccaga agatatttca agcaaccaaa tcgtgcatga cacctatcca
     8761 aatgccaatg tcacagcaga ggtcttggtt tctgagctgc ttggatctga aaccatgctt
     8821 tatgttaagc ttggtcaaac agagtttgct tcacgagttg atgcgcgtga cttccacaat
     8881 ccaggtgaaa aggttagctt gaccttcaat gttgctaagg ggcatttctt tgatctagaa
     8941 acagagcaag ctattcgcta ataacacctc ctagaataaa atcctcatct tgcttgagga
     9001 ttttttaaca aaagaaaatg caagcgattg cgctatcaaa aagaaaaagg gatttatcat
     9061 aaagacaaca gatgttctgt agtgctaggc gatcataatg atggcacgaa atagcaggag
     9121 actgtttagt aataaggaga tatgatggaa aaacactggt ggcataaagc gacaatttat
     9181 caaatttacc caaggtcctt catggataca agtgggaatg gtattggtga tttaaaagga
     9241 atcacaggta agctggatta tctacaggag ctagggatca cagctatttg gctgtctcca
     9301 gtttatcaat caccaatgga cgataacggc tatgatattt cagactatca ggccattgca
     9361 gctatttttg gtgatatggc tgatatggac gagctgcttg atgaggccaa gcagcggggg
     9421 atcaaaatca tcatggattt ggttgtcaat cacacctctg atgagcacgc ttggtttgtg
     9481 gaggcaagag aaaatcctga cagtcctaaa cgagattatt acatttggcg tgatcagcct
     9541 aataatctca tgtcgatctt ttctggctct gcttgggaat atgatgatgc ctctgggcag
     9601 tattatctgc acatattcag taaaaaacag cccgacttga attgggaaaa tgctgaattg
     9661 cgtcaaagca tttatgacat gatgaatttc tggattgata aggggatagg tggctttcgc
     9721 atggacgtca ttgacctgat tggtaagatt ccggattctg aaattacagg caatggccca
     9781 aggctgcatg aatacctcaa ggagatgaac caggcaagct ttgggaatca tgacctgatg
     9841 actgttggtg aaacatgggg cgctacaccg gaaattgctc gtcagtattc acgtcctgaa
     9901 aataaggagc tgtcaatggt ctttcaattt gaacatatcg gcttgcagca taagccaaat
     9961 gcttctaaat gggattacgc agctgagttg aatgttccgg ctctcaagga gatttttagc
    10021 aagtggcaga cagagctaaa gctaggtgaa ggctggaact cccttttttg gaacaatcat
    10081 gacttgcctc gtgtcgtctc catttgggga aatgatacag tatatagaga gaagtctgcc
    10141 aaggcaatgg ctattttgct gcatttaatg cgtgggacac cttatattta tcagggtgaa
    10201 gagattggca tgaccaatta cccctttgag cgcttgagtg atgtgaatga tattgaatca
    10261 ctgaattatg ccaaggaggc tatggctaat ggcatgtcag aggaggctgt tcttgattgt
    10321 atttgtaggg tgggtcgaga caatgcaaga acaccaatgc aatggagcag tcaaaagaac
    10381 gccggctttt caactgctga tcagacctgg ctgcctgtca acccaaatca tcaagagatt
    10441 aatgtggcta gtgctctagc tgatcctgat tctgtttttt acacctatca aaagcttatt
    10501 cagctgcgtc agacacagga ttggctggtg gaggcagatt atcagctgct ggaaacatca
    10561 gataaggttt ttgcctataa gcgtcagctt ggtagagaga cttaccttgt tgttgtcaat
    10621 ctgtctaatc aagagcagtt ttttgaagaa agtcttcata aggcccaagt gattatcagc
    10681 aataccgatg tgcaggcagt cgtagaaagt caacagctgg agccttggga cgccttttgt
    10741 gttaagcttg atgagacctt gtagcctagc tgcttgctgt gcctcagctc aataatcgta
    10801 gcgattcttt gagaattttg acaaattgct gtatgattag tagaagaatt agatacaaaa
    10861 gaggaggctg agatgaccgt tgaagaaacc atgacctttg caaaaagcat tgcagcattt
    10921 agataggtag agattagtga ggtagtcact aggctagcag caggtgagga catcaccgtc
    10981 tttttaggca gagcgacctg tccttattgt cgtcgctttg cacccaagct agcaagcgta
    11041 gcaaggcagg agcataagga tattttcttt gtagatagtg aagactcaac agagcttgca
    11101 gacctgcagg cctttcgtga gcgctatggg cttgctactg tgcctgccct gctcattagt
    11161 cgtcatcagg aggtcaaggc agtctgtgat tctagcttga ctgaggaagc cattttggct
    11221 ttcctagagc agtgacagac agctaattat ctggtgcaag taatagaaat gtaatcagtc
    11281 atgtcttgct atgtgagtcc aaatctgcta tagtaggaca tgacttttag acgaaataag
    11341 gagatattat gggcttacca acaattttaa tgtttgttgt catgattggt ttaatttggt
    11401 ttatgcagcg tcagcaaaaa aagcaggcgc aggagcgcca aaatcagctt aatgcgattg
    11461 aaaaaggcga tgagattgtg acgattggtg gcatgtttgc agtggtcgat gaggttgatt
    11521 tagcagcaaa gcgaattgtc ttagatgttg atggtgtcta tctgccattt gagctatcag
    11581 cgatcaagcg cgtggtcgaa aaaggaagtg cagtgacatc agctgatgtg gatacgacag
    11641 agactgcagt tgatgacaca gcggttgagg cttcagacga agctgaatca gctattgaga
    11701 caaattaaga aaatgaggtc tgaagcatta gtgtttcaga cttttttagg tgatgatagc
    11761 aggtagccag acagagctgt catgtgctat ggaaatatcg tctacaacga gaaaaagcga
    11821 gccaaaccgc atgaaatatg gtaaaatatg aggtaagtat gcttgtgaat aaggaaaaaa
    11881 catgtttgga ttaaaagcga agtcaaaaaa aatcgttttg gataggattc caaagcacat
    11941 tgggatcatc atggatggta atggacgctg ggcgaaaaaa cgcttaaagc cgcgtgtctt
    12001 tggacataag gcgggtatgg acgctttgca ggaggtaacg attgcagctt cagatttagg
    12061 ggttaaggtg ttaacagtct atgccttttc gacagaaaat tggtcaagac cacaagatga
    12121 ggtgagcttc attatgaacc tgcctgttga gttttttgat aagtatgtgc ctgagctgca
    12181 caaaaataat gtcaaggtgc agatgatcgg tgagaccaac cgcctaccta aggatacact
    12241 aaaggccttg gaagcagcta ttgctaagac aaggcaaaat actggcttga ttctaaactt
    12301 tgctcttaat tatgggggtc gcgcggaaat caccaatgct gtcggtctca ttgctcaaga
    12361 tgtcctagac gccaagctga accctggtga cattaccgag gatttgattg ccaactattt
    12421 gatgacggat catttgccct atctctatcg cgatcctgac cttattatca gaacgagcgg
    12481 tgaattgcgc ttgagtaatt ttatgccttg gcaatcagcc tatagtgagc tttactttac
    12541 gccggtgctg tggcctgatt ttaaaagagc tgaactacta aaggccatag aggattataa
    12601 ccatcgtcat cgccgtttcg gtgctattta aggagagagt atgagagaac gtttcatttg
    12661 gggtggtgtt gcagctgctg ttttcctacc ctttttactc attggcagct taccctttca
    12721 attgtttgta ggtgtgcttg ccatgattgg tgtatcagag ctgttaagaa tgaagaggct
    12781 tgaggtcttt tcctttgagg gtgtttttgc catgctagca gctttcgttt tgacagtgcc
    12841 gttggatcat tacctgacct ttttgccgat ggacgctagt tttgcttgtt acgggctgtt
    12901 ggtgtttttc cttttagcag gaatagtgat tagcagcgat tcttatggct ttgaggatgc
    12961 tagctttccg attgcagcta gcttatatgt tggtattggc tttcataatc tggttaatgc
    13021 gcgaatgaca gggatagaca aggtttttct ggctcttttt attgtctggg cgactgatat
    13081 tggagcttac ttgattgggc gccgatttgg taagcgaaag ctcctgccaa aaatatcacc
    13141 caacaaaaca attgagggca gccttggtgg tatagtcagt gcggtgcttg tttcctttgt
    13201 gtttatgctc tttgataagg ctgtttatgc tcctcatcat tttggaacaa tgttgatttt
    13261 ggtggctctt ttttctattt ttgctcagtt tggagatttg gttgaaagtg ctgtcaaaag
    13321 acatttcgga gttaaggact caggcaaatt gattccaggc catggtggta ttttagatcg
    13381 ttttgattcg atgatctttg tttttcccat tatgcatcta tttgggttat tttaaagctc
    13441 attatcaata gactgaaagg aaatctatgt taggaataat tacctttatt attatttttg
    13501 gtattcttgt gcttgtccat gagtttggcc atttctattt tgctaaacga tctggtattt
    13561 tagtcagaga gtttgctatt ggcatgggac caaaactctt ttcgcatgtt gatcagcaag
    13621 gaacgcttta cacgatccgg ctattaccgc ttggtggcta tgtgcgaatg gcaggctggg
    13681 gtgatgacac aactgagata aaaacaggaa cgcctgctag cttaacgctt aatgatcagg
    13741 gcttggtcaa gcggattaac ctgtctcaga gcaagcttga tccgactagc ctgcctatga
    13801 atgtgactgc ttatgactta gaagataagt tgacgattac agggctggtt cttgatgaga
    13861 tcaagaccta ttcggtagac catgacgcga ccattgtcga ggaggacggt acagagatcc
    13921 ggattgcgcc gcttgatgtt cagtatcaaa acgcaagcat tggcggtcgt ttgatcacca
    13981 attttgcagg acctatgaat aattttattc taggtattgt tgtctttatt ttgtttgcct
    14041 ttgttcaagg tggtgtggct gattatcata gcaaccatat tcgtgtggtg gaaaatggcg
    14101 cagcagccaa ggctggtatt agagacaatg atcagatttt agagattaat catcaaaaga
    14161 ttaatgactg gtatgagttg acgcaggccg ttactgattc agcagcagat gttaaggcta
    14221 agggcaagct agagattacc tatcagacag gtgatcaggt taagactata gcactgaagc
    14281 ctgaaaaaaa aggcgatcag taccttattg gtgtccagta cccactaaaa acaagtctga
    14341 cagacaagct aataggtggc tttgagatgg ctggtaatgg tgctctagtg attgtcactg
    14401 ctctaaagag tttgattacc tcctttagcc tagataaatt aggtgggcca gttgccatgt
    14461 atcagatgtc caatcaggca gcaaagaatg gtttagagtc tgtcttgtcc ttgatggcaa
    14521 tgctctctat caatttaggg atttttaatt tgattccgat tcccgcacta gatggtggta
    14581 agatcctgat gaatgtgatt gaagcacttc gtcgtaagcc attaaagcaa gagacagaga
    14641 cttatattac ccttgcaggt gttgcgatta tggtggtact catgattgca gtgacctgga
    14701 acgatattat gcgagccttt ttccaaggct gatggtctct ctcatttaaa ggagagccta
    14761 aaaggcttaa tgtaacagaa ataacaagag atatagtgtc attattgtgg ttctaagacc
    14821 ttgcaaatgc agcaaaagct tagccaatat agctcatttt gtctcttttt tagaaatgaa
    14881 ttctcaacga aaggaaagag agctgttgac caagctgggc taaggcctac agctgaaatc
    14941 aaaatgctag acctgctatt agtctaaggg cgttttgagc tgctctctat agcttatttt
    15001 aatgaaacaa agtaaaatgc ttatcccaac cctgcgcgaa atgccaagtg acgctcaggt
    15061 aatcagtcat gccctcatgg tgcgtgcggg ctatgtccgt caggtatctg ccggtattta
    15121 tgcctatttg ccattagctc atcgtacaat tgaaaaattc aagacgatta tgcggcagga
    15181 atttgacaaa attggtgctg ttgaaatgct agcacctgcc cttttaacag ctgacctctg
    15241 gcgtgaatca ggccgctatg agacttacgg tgaggacctt tacaagctaa aaaaccgcga
    15301 caaatcagac tttatcttag gtcctaccca tgaagaaacc tttactacac tggtgcgtga
    15361 tgcggttaaa tcctataagc agctgccgct caatctgtat cagattcaat ccaaatatcg
    15421 tgatgaaaag cgtcctcgta atggcctgct tcgcacacgt gaatttatca tgaaggacgg
    15481 ctatagcttt catcaaagct atgatgattt agatgtcacc tatgacgcct atcgtcaggc
    15541 ctatgaggct atttttacca gagcaggctt ggatttcaaa ggaattatcg gtgatggtgg
    15601 tgctatgggt ggtaaggatt cgcaggaatt tatggctatc acaccggacc gtactaattt
    15661 agaccgctgg ctggtcttag acaagtctat tccgtcattg gctgacattc cagaggaggt
    15721 cttggaagag attaaggccg agctggcttc atggctggtt tcaggagagg acaccattgc
    15781 ttattcaagt gaatcaagct atgctgctaa ccttgagatg gcaaccagtg agtacaagtc
    15841 ctcatcaaag gtaacagcct tagatgatct cgtcgagatt gagacaccaa attgtaaaac
    15901 cattgatgaa gtggcggcct ttcttgacgt tgctgagcat caggtcatta aaaccctgct
    15961 ctttatggtg gaccatgagc ctgtgcttgc tttattggtt ggaaatgacc agatcaatgc
    16021 tgtcaaattg aaaaaccacc tcggtgcaga cttcttagag ccagctagcg aggaggaggc
    16081 gcgtgctatc ctaggtgcag gctttggttc acttggtcca gttcatttga cagatggtat
    16141 ccgtattgtg gctgatcgta aggtccaaga ccttgctaat gctgtagctg gagccaataa
    16201 agatggttat cacctgactg gtgtcaatcc aaatcgtgat ttccaagcag agtatgctga
    16261 tattcgtgag gtaaaagagg gagagacctc tccagataga catggcgtgc tgcagtttgc
    16321 cagaggtatt gaaatcggtc atatctttaa gctggggacc cgctattctg atagcatggc
    16381 agctaatatc cttgatgaga atggcagagc agttccgatt gtcatgggct gctatggtat
    16441 tggggttagt cgtatcctat cagcagtcat tgagcagcat gctcgtctct ttgtcagcaa
    16501 gacaccaaag ggtgattatc gctatgcttg ggggattaat ttccctaaag agctagctcc
    16561 gtttgatgtg catttgatta ccgttaatgt caaggatcag gaggcgcagg acctgacaga
    16621 aagagtagag gctagtctga tggccaaggg ctatgatgtc ctcactgatg accgcaatga
    16681 gcgtgtcggc tctaagttct ctgatagtga tttgattggg cttccgattc gtgtgacgat
    16741 tggtaaaaaa gcagctgagg gcattgttga gatcaaaatc aaagcaacag gtgacagcat
    16801 tgaggtgcac gctgatagct tgattgaaac tcttgacatt ctcacaaagg acaactaatg
    16861 atatgaggtc aacgatggtt gatctctttt tgtatgctat aatgaaagca tgacaattga
    16921 ggaattacag cagctggtgc tagcagatca tgagctaatg actattctaa gcattataga
    16981 gaccttgcct ttaaaggatt gttggctggc agcaggtgca attcggaacg ctatttggaa
    17041 tcatttagct tatgggatag gctttgatcc gctgacagat gtagatgtgg tcttttttga
    17101 ccctgagatc tcttacgaag ctgagcagct gctagaagag cagcttaagt gtgcttatcc
    17161 catgtaccaa tgggaggttc gcaatcaagc ctatatggca gcacataacc ccaagacgcc
    17221 tccttatcga tctagtcaag acgctatcac aaagtatccg gagcgctgta cagcgattgc
    17281 tgttagactt gtaggaggac agctagaggt ttttgctccc tatggtttag cagacattag
    17341 tcactttgtc tgtcggccaa caccgcattt tttagaggat tcagagcgta tggactgcta
    17401 taggcagcgc ctagcaaaga aggactggca caagaaatgg ccacagctga cctaccacga
    17461 ctgctaagtc agaggaaaca aagcaggcta ggagctccgt acagccaagc aattagtccg
    17521 ctcccagacc cgttagctac agctctcacc tagtcaaaac aagcacatga acagatcatt
    17581 ggcagatagc cttgcctttg cagatattgt cacaccctat ttagctgtac catgtgtctt
    17641 atgataggcg tgatagtgct gtcagaagcg ccagctgagc cagaaaaagc gttaagccta
    17701 cagcaagggg cttttaacct ttggtatgtt gtcttgtagg agaggtcgaa aatgatcact
    17761 atttatgata aaatagaccc taagaaaatc aggagaaagc tatgtcagat ttattcggta
    17821 aattgatgga acaaattgaa atgccacttg agataagaca atcaagtgcc ttttcgtctg
    17881 ctgatattat cgaggtcaag gtgcattcag tgtctcgtct gtgggaattt catttttcct
    17941 ttgcagaggt tctcccgata gagagctatc gagagctgtc agataggctt gtgagaacct
    18001 ttgaggcagc agatattaag gtaacatttg acatcaaggc agagacaatt aattattcgg
    18061 atcagctgct gcaagcctac tatcaagaag catttgagca tgagccctgt aatggggcta
    18121 gcttcaagtc atctttttct agacttcagg tcaggtatga ccatcatcag ctgatcatta
    18181 tggcacctga ctttgtgaat aatgatcact ttaggaaaaa tcatttaccc aatctggcag
    18241 ctcagtttga gcgctttggc tttgggaggc tagcgattga tatggtgtct gatcaggaga
    18301 tgacagacca tttgacaaag gactttgaga ccaaccgtca ggctctggtg gaaaaggctg
    18361 tacaggataa tatcgcagca cagcaatcat tggaggccat gcagccacca gctgaggagg
    18421 cagcaccaag cccaagcctt gactatagag agcgtatggc tcagcgccaa gcaagctttg
    18481 ataaggcggt cattacacca atgattgagg tggatacaga agaaaatcgc attgtttttg
    18541 aaggaatggt ctttgatgtg gagcgcaaga cgacaagaac aggccgccat atcatcaact
    18601 tcaagatgac agattacacc tcctcctttg ccatgcaaaa atgggccaaa gatgacgatg
    18661 agctcagaaa atttgatctg attgcgaagg gagcttggct gcgcgttcag ggaaatatcg
    18721 aaaacaaccc cttcaccaag agcctaacca tgaatgtgca gcaggttaag gcgattgttc
    18781 accatgagcg taaggatctc atgccagaag ggcaaaagcg tgttgaattt catgcacaca
    18841 ctaatatgtc cacaatggac gctctaccga cggtagaaga cctgattgat acagcagcca
    18901 ggtggggaca tcaggcagta gcgattactg accacgctaa tgttcagagc tttccgcatg
    18961 gctatcatag agcacgcaag gcaggaatca aggcaatctt tggcttagag gccaatattg
    19021 ttgaggataa ggtacctatt tccttcaatc ctgtcgctat ggacctgcat gaagccacct
    19081 atgttgtctt tgacgtggag accaccggcc tttctgccat gaacaatgat ttgattcaga
    19141 tcgcagcttc caaaatgttc aagggaaata tcattgagca gtttgatgag tttatcaatc
    19201 caggccaccc cttatctgct tttacaacag aattgacagg gattacagat aatcatttgg
    19261 taggagctaa gcctatacag caggtgttag aggcatttca ggccttttgt cagggcacta
    19321 tcctagttgc ccacaatgct agctttgacg tgggatttat gaatgccaac tacgatcggt
    19381 atggtttagc aaaaatcagc cagccagtta ttgacaccct ggagcttgcc agaaacctgt
    19441 accctgagta taagcggcat ggcttgggcc ctttgactaa gcgctttcag gttagccttg
    19501 agcaccatca catggccaat tacgatgctg aagcaacagg gcgtttgctc tttatcttcc
    19561 taaaggaagc tagagaaaag catgggatta caaacctgct tcagctcaat acagacttag
    19621 tggcagagga ttcctataag aaagcacgga tcaagcacgc cacgatctat gttcaaaatc
    19681 agctaggtct caaaaacatg tttaagctgg ttagcctttc aaatgtgaaa tattttgaag
    19741 gtgtgcctag aattccaaga accgtccttg atcagcatcg tgaaggcttg ctgcttggga
    19801 cagcctgctc agacggcgag gtctttgacg ctgttttgac ccaaggaatt gacgctgctg
    19861 ttgatctggc caaatactac gattttatcg aaatcatgcc gcctgcaatt taccagccct
    19921 tggtagtccg agagctaatc aaggatcaag caggagttga gcagattatt cgcgatttga
    19981 ttgaggtcgg ccgcagagct gaaaagcctg tcctagctac tggaaacgtg cactacattg
    20041 agccagagga cgccatctat cgtgacatta tcgttcgtag tctagggcaa ggtgccctga
    20101 ttaaccgtac tattggccgc ggagaggctg ccaagcctgt cccgctacca gaggctcatt
    20161 ttagaacaac caatgaaatg cttgatgatt ttgccttttt aggtcaggac ttggcctatg
    20221 aggttgtggt gcaaaatacc caagcccttg ctgatcgaat tgaaaaggtg gaggttgtta
    20281 aggatgatct gtacacccca tatattgata aggcagaaga aaccgttgct gagctgactt
    20341 atcaaaaggc ctttgctatc tatggcaacc cacttccaga tatcattgat ctgcgcattg
    20401 aaaaggagct aacgtccatt ttgggaaacg gctttgcggt gatttatcta gcctcacaaa
    20461 tgctggttaa tcgctctaat gagcgtggtt atctggtagg ctcacgtggc tctgttggtt
    20521 caagctttgt tgcgaccatg attggcatca cagaggtcaa tccaatgccg cctcattatg
    20581 tctgcccaag ctgccagcag tcagagttta tcacagatgg ctcggtcggc tctggctatg
    20641 atttgccaaa caaggcctgt cctagatgtg ggacgctgta caaaaaggac ggacaggata
    20701 ttccttttga aaccttcctt ggctttgatg gtgataaggt tccagatatt gatttgaact
    20761 tctcaggaga tgatcagccc aatgcccact tggacgttcg tgatatcttc ggggaagaat
    20821 acgcctttcg tgcaggtact gttggtactg tcgctgaaaa aacagcctat ggctttgtca
    20881 agggctatga gagagattat ggcaagtttt acccagatgc agaggttgat cgtctagctg
    20941 ctggtgctgc tggtgttaag cggacgactg gtcagcaccc tggtgggatc gttgttatcc
    21001 ctaactatat ggacgtttat gattttacac ctgtgcagtt tccggcagat gatgtgacag
    21061 cctcatggca gacgacccac tttaatttcc atgatattga tgaaaatgtc ctaaagctcg
    21121 atgtactcgg tcatgatgat cccaccatga ttcgtaagct gcaggattta tcaggtattg
    21181 atccgattac tattccagca gatgatcctg acgtgatggc acttttttct ggaacagagg
    21241 tgctcggagt gactcctgaa caaattggaa caccaacagg tatgcttggg atcccagagt
    21301 ttggaacgaa ctttgttcgt ggcatggtga atgagaccca cccaacgacc tttgcagaat
    21361 tgctgcagct atcaggtcta tcgcatggaa cggacgtctg gctgggtaat gctcaggatc
    21421 tgatcaaaga aggcattgcc accctaaaaa cagttatcgg ttgtcgagat gacatcatgg
    21481 tttacctcat gcatgctggt ctagagccta agatggcctt taccatcatg gagcgtgtgc
    21541 gtaaggggct ctggctaaag atttccgagg aggagcgcag ctcctatatc aaggccatgc
    21601 ggcaaaacaa cgtcccagac tggtacatcg aatcctgtgg taaaatcaag tacatgttcc
    21661 ccaaggctca cgctgccgcc tatgttttga tggcattgcg agtggcttat ttcaaggttc
    21721 atcaccccat catgtattac tgtgcttatt tctctattcg tgccaaggcc tttgagctca
    21781 aaaccatgag tggtgggcta gctgctgtca aggctcgcat ggaggacatc agcaacaagc
    21841 gcaagcgcaa tgaagcctca aacgttgaaa atgacctgtt taccacttta gaaattgtca
    21901 atgaaatgct tgagagaggg tttaagtttg gcaagctaga cctttacaag agcgaggcaa
    21961 ctgagtttca aattgaaggg gataccctaa ttccaccttt tattgcctta gaaggcttgg
    22021 gagaaaacgt tgctagacaa atcgtcaagg ctcgccaaga tggtgaattt ctatcaaaaa
    22081 tggaattacg caagcgtggt ggtgcttctg ccactctagt tgataagatg gacgagctgg
    22141 gcattttagg aaatatgcca gatgacaatc agctgagtct atttgatgac tttttctaag
    22201 attgcacagc cctaatattg tctatgttag cttgtcatac agtgaagagc agggcaggaa
    22261 ggcttcctgt cctctttttg tcaatacgca aagaaagccc aaaaaagaac gaggaaaagc
    22321 atgaatgaat tagacaaaaa tcctgcctta aaggcaatgg ttgtttttag aaaagcacag
    22381 cgtaccttag atgctcaaag ctccgccttt tttcaaaagg ccaatctgac tcctacccaa
    22441 tttagcgtct tagaggtgct ttattccaaa ggaagcatga gaattaacaa gctcatcggt
    22501 tctctcttgg caacctctgg caatatgacc gtagtgctga aaaatatgga gagaaatggc
    22561 tggatcagcc gctgccaaga tgctaaagat aagcgtgcct gcttggtaca gctaacgcca
    22621 gagggcaaag ccttgattga gactatccta cctgagcata tcaaacgtgt tgaagccctt
    22681 ttttcagtgc tgacagagac tgagcaaaaa caattgatta cgcttttaaa gaaatttaaa
    22741 gaactctaag caaatggctt tacaggatct cccaagtagg atataatcac tacatagtac
    22801 aaaaagatac taactagtca taataagtca tcaagacagc agatggctag ttaccagata
    22861 atcaatggga gacaaagcat gaaacaaatt ttaatcatta atggttcatt acggacaggt
    22921 tcatttaatc atcagcttgc tcaagcggct gagcagctac ttgaaggcaa ggcagctgta
    22981 tcttacttgg actgggaaca ggtacctatg tttagtcagg atttagaagc aagcacccct
    23041 gagtcagtgg caggcgtacg agaagccatt caagcagcag atgctatctg gattttttca
    23101 cctgtctata attttgcaat cccgggctct atcaaaaacc tattagactg ggtatcacgc
    23161 gcccttgatt tgtcagaccc atcaggacca tcagcaatca atggtaaggt agttaccgta
    23221 tcatctgttg ctaatggtgg gcacgagcag ctatttgcgc aataccagga cctgctgccc
    23281 tttatccgta cgacagtagt tggtaacttt accaaagccg ctgtcaatcc agaagcatgg
    23341 gcgacaggtg ttcttgatat ttctgaggaa acaaggcaaa gccttgcagc acaggcagaa
    23401 gcccttcttg aagccattca ctaagactct ctgagcatta aacagataaa gctgcagcta
    23461 ggatcaaaaa gcagctagac acataaaaag agcttaaacc agaaatgtac ggcactccaa
    23521 aagctagaca aaaactctag cgattggggt acaggtcaaa acggttttaa gctctttttt
    23581 agacttattt tatagtagta acttaattaa gaattagcat accctcttta gcctcaaagg
    23641 ggtttttcgc attaatacgg tcatagaata agacaccatt aatatgatca atctcatgct
    23701 gaaccacgat agcattgtag ccctttagct taatgcggtg cttttcattg tgcttatcgt
    23761 aatattccac tgtcacacgc gcatgacgga cgacatagcc ttccaccaca cgatcaacag
    23821 acaaacaccc ctcaccgtca gcaagagcag cgtcttgaac agaatgagac acaattttag
    23881 gattatagag cacttcctcc atgctgtaag cctccttagg tggattgccc tcgctgtctt
    23941 caggatttgg aaccagaaca gcgatgatac gctttgacac atcaatctga ggtgctgcta
    24001 gaccaactcc tgctcgaagc cctaattttt ctcccatgac agggtcttga gaatgcttta
    24061 aaaattgcat cattttttca cctaaaatga tgtcatcatc actaagagga aactcgacct
    24121 ccttagccac agcacgaagc gtaggattgc cttcgcggat aatatcattc atatcaatga
    24181 gatgctgtgc tttaattaat ttatcttgtg cagacatttt gcctcccttt ttttatattt
    24241 gataatggct ttactatatc acaaaatcct tatttttaaa agataaggca ggccagtgat
    24301 gacga
//
LOCUS       DARYXW010000022        24020 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.022, whole genome shotgun sequence.
ACCESSION   DARYXW010000022 DARYXW010000000
VERSION     DARYXW010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24020)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24020)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24020
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.022"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            85..366
                     /locus_tag="TV191_000719"
     CDS             85..366
                     /locus_tag="TV191_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEL1507253.1"
                     /translation="MPTPLEQRQLKQQKQEQVSQQKFQEFQDLNGHSSKLKELIFFAR
                     IAVFSLITVLFAFVLLVMNLAPVWAFLIASAISLAITSFLSKAITLLMS"
     gene            complement(492..917)
                     /locus_tag="TV191_000720"
     CDS             complement(492..917)
                     /locus_tag="TV191_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEL1507254.1"
                     /translation="MSNFFKTLVIGVASGAATAYFLSTEKGKVLKARAQRAYEAYRQN
                     PEEYHQMAKEKGSEYSQLARHTFNDLKTRFESGDMTTDQVFDFIKEKTSQFVHQAKEA
                     ASEHDKADDVIIDLDEEDIIINYPEDDSEKEAASNKSEE"
     gene            complement(914..1318)
                     /locus_tag="TV191_000721"
     CDS             complement(914..1318)
                     /locus_tag="TV191_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007892823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEL1507255.1"
                     /translation="MNLVGISLLIIALAFVALVIFLIVVLKKVSEAVDEAKKTITVLT
                     SDVNVTLYQTNEILAKANVLVDDVNGKMTTIDPLFVAIADLSESVSDLNVQARHLGRR
                     ATNATSNAAKVGKVALVGKVASKLFGKKEKRS"
     gene            complement(1340..2119)
                     /locus_tag="TV191_000722"
     CDS             complement(1340..2119)
                     /locus_tag="TV191_000722"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEL1507256.1"
                     /translation="MINPIAFKLGPLSLHWYAVCILVGLLLAVYLAAKEAPRKKMTSD
                     DIIDFILIAFPLAIIGARIYYVAFEWSYYSQHLSDIFAIWNGGIAIYGGLITGTIVLF
                     VYCYYKVLNPIHFLDIAAPSVMLAQAIGRWGNFFNQEAYGRAVSQLNYLPSFIRQQMF
                     IDGSYRVPTFLYESMWNLIGFVIIMVWRRKPRSLVDGDIISFYLIWYGCGRLVIEGMR
                     TDSLMLLGIRVSQYMSVLLIIIAIVFIFKRHRQKGISYYQE"
     gene            complement(2116..3048)
                     /locus_tag="TV191_000723"
     CDS             complement(2116..3048)
                     /locus_tag="TV191_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEL1507257.1"
                     /translation="MTVTVKMLVTKVKLDVVYATDDLLEKEITTSDISRPGLEMTGYF
                     DYYAPERLQLFGMKEWSYLTQMTSHNRYSVLKEMFKKDTPAVIVSRGLAIPEEMVQAA
                     QEEGIALFSSRVSTSRLAGEMSYFLDASLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDVFAKDEETLWGEPAEILRHLLEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAIYLENFEAGKVFDRLGNGNEEITFSGVSIPRIRIPVKTGRNVSVVIE
                     AAAMNHRAKEMGFDATKTFEERLTRLISKNEEGK"
     gene            complement(3326..3598)
                     /locus_tag="TV191_000724"
     CDS             complement(3326..3598)
                     /locus_tag="TV191_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEL1507258.1"
                     /translation="MESKFYKQRKHKLVAGVISGLADKYGWDLPLARVLAALLIYFTR
                     FGVVIYILLAIFLPYKEDLLEERYGRGPRRRKDADVLNDEDEGWFW"
     gene            complement(3662..4099)
                     /locus_tag="TV191_000725"
     CDS             complement(3662..4099)
                     /locus_tag="TV191_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003097487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEL1507259.1"
                     /translation="MSLTDYVREVSLADFGKPFKHQASWNRRLRTTGGRFFPKDGHLD
                     FNPKILEEHGETVFRQIVRHELCHYHLYFEGLGFRHKDQAFKELLDQVDGLRYAPKLQ
                     SHQANYLYICQDCGQAYDRKRPINLAVFACGRCHGRLIEKNQS"
     gene            complement(4086..6218)
                     /locus_tag="TV191_000726"
     CDS             complement(4086..6218)
                     /locus_tag="TV191_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEL1507260.1"
                     /translation="MENMNHQNISEALGVTPKQISQVLTLTAEGNTIPFIARYRKEAT
                     GNLDEVVIKAIIDMDKSLTQLRERKDTILAKIEGQGKLTAALKEAIEAADKLADLEEL
                     YLPYKEKRRTKATIAREAGLSGLARLILQNAQDLETKAEAFITEGFSDPQAALAGAVD
                     ILVEAMSEDSRLRSWTYNEIWKYSRITSSLKEASLDDKQVFQIYYAFSETVSNMQGYR
                     TLALNRGEKLGVLKVSFEHHIDKMLRFFSLRFKEHNAYIDDVINQTIKKKIVPAMERR
                     IRTELTEMAEDGAIKLFSENLRHLLLISPLKGKMVLGFDPAFRTGAKLAVIDPTGKLL
                     TTQVIYPVAPANQAKIQAARVALAQLITDYQIDIIAIGNGTASRESEAFVAEVLKDFP
                     ETSYVIVNESGASVYSASELARHEFPELTVEKRSAISIARRLQDPLAELVKIDPKAIG
                     VGQYQHDVSQKKLSEHLDFVVDTVVNQVGVNINTASPALLAHVSGLNKTISENIVRYR
                     EENGEITSRAEIKKVPRLGAKAFEQAAGFLRIPNAKNILDNTGVHPEAYPAVKKLFQL
                     LAIKDLDEPARAKLQAVNLEEMAEQLTLGQETLKDIIADLLKPGRDLRDDFEAPVLRK
                     DILSVKDLAVGQRLEGTVRNVVDFGAFVDIGVHEDGLIHISEMSEAFVNHPSQVVSVG
                     DLVTVWVSKVDLDRHKVNLSLVPPRESD"
     gene            complement(6386..6712)
                     /locus_tag="TV191_000727"
     CDS             complement(6386..6712)
                     /locus_tag="TV191_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507261.1"
                     /translation="MKKLLLTSAAALALATVAVSTTKVEAFSRGHVIEHTINDTKSLS
                     AARWGSRLQILNLLTRFKHKLGEDGFRSYNRQFRARVGAAKSVSEIDELYNKFEKELE
                     ELEDLT"
     gene            complement(6988..7740)
                     /gene="pstB"
                     /locus_tag="TV191_000728"
     CDS             complement(6988..7740)
                     /gene="pstB"
                     /locus_tag="TV191_000728"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEL1507262.1"
                     /translation="MGAFSTKQLNVFYGAFQALKDISIDIPENQITALIGPSGCGKST
                     FLKTLNRMNDLIPSCRIEGEVLLDNQDIYAKAINLNSLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGLKDKKTLDQLVEQSLRGAAIWDEVKDSLKKSAMSLSGGQQQRLCIARA
                     LAVAPDVLLMDEPTSALDPISTLKIEDLVQQLKQDYTIIIVTHNMQQASRMSDKTAFF
                     LTGDICEFGDTAELFTKPKDKRTEDYISGRFG"
     gene            complement(7742..8557)
                     /gene="pstA"
                     /locus_tag="TV191_000729"
     CDS             complement(7742..8557)
                     /gene="pstA"
                     /locus_tag="TV191_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEL1507263.1"
                     /translation="MTNYLLKALVYLLSLLTFGSLFLIIAFMLIKGLPSLSLSLFSWT
                     YTSDNVSLMPSIISTVSLVLGTLVLALPIGVFAGFYLVEYAKQDSLWVRAIRLAADTL
                     SGIPSIVFGLFGMLFFVVFFGLQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDHLRQ
                     ASLGLGAGKLRTIFKIVLPAAMPGILAGVILAIGRVVGETAALMYTLGTSTNTPTSLM
                     SSGRSLALHMYMLSSEGLHVKEAYATGVILLITVLLINALSSLLSRRLVKGVV"
     gene            complement(8550..9413)
                     /gene="pstC"
                     /locus_tag="TV191_000730"
     CDS             complement(8550..9413)
                     /gene="pstC"
                     /locus_tag="TV191_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEL1507264.1"
                     /translation="MNKQAFKEDFFKVIFFLSAAMAIIAICLICIFIFSNGLPFIAKY
                     GMRAFLLGNDWSPSNQPASYGILPMIAGSFVITLGAMVIGVPTGILTSVFMVYYCPKA
                     CYGFLKSAVNLMAAIPSIVYGFFGLQVLVPWIRSFAGNGMSVLTASLLLGIMILPTLI
                     SLSESAIRAVPKAYYSASLALGASHERSIFRVILPAAKSGLFSALILGFGRAIGETMA
                     VILVAGNQPVLPSGLFEGTRTMTTNIVLEMAYASGQHREALIATSAVLFGFILIINAC
                     FAYVKGKSAHD"
     gene            complement(9483..10355)
                     /locus_tag="TV191_000731"
     CDS             complement(9483..10355)
                     /locus_tag="TV191_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HEL1507265.1"
                     /translation="MTIKKMLIMAAIGLSGLGLAACGNNSADAGKAADRIDLVSRENG
                     SGTRGAFTEMTGILKKDGDKEIDQTAKTAIIQNSTEGVISSVKGNSRAIGYISLGSLN
                     SDVAALKVNGVKASRETILEGKYPLQRPFNIVWSSDLSGVGKDFITFIDSKQGQEIVR
                     DNRLIEAKTDAPAYSSKGLSGKLSIVGSTSVSPLMEKLAEAYKKENPAISIDITSNGS
                     SAGITAVKEKTADIGMVSRDLTTEESKGLIDDAIALDGIVVIVHKDNKVSNIGIDVLA
                     DVFSGKLTSWDKVK"
     gene            complement(10514..11839)
                     /locus_tag="TV191_000732"
     CDS             complement(10514..11839)
                     /locus_tag="TV191_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEL1507266.1"
                     /translation="MIGHLRRLSMLLGLCLLAALGLIWQGPHQVLTLVVLCTGLVASF
                     YVLSMLFRWEREFRALHHHLLTASDHFLLVGQADLSAYAKQLTELKSDLLQKEARLKA
                     LSKNVEAVTSHLTMGMLLVSNQRELLLTSKSLPAYFPEAKPPFVVLEDLKRMDLIALV
                     NQVFDQKQTLKKELTGLHDGDLILEVTLVPIFNQSHVVKEILVLLYDLTAIRHYERLN
                     LEFIANASHELRTPVTSIKGFAETIKEMPDDETSLKEDFLDIIYNESLRLERIVEHLL
                     TLSKANKTPLDLTEFQLRNFLLYTGQSMRPQLEQKQLELSYALEDSIVVTSDQYLLSQ
                     IMLNLLSNAIQYTDNGGRIQLSSQRVAGGVAITVADTGIGISQIELDRIFERFYRVNK
                     GRSRQSGGTGLGLAIVKELSQLLGGQITVTSQLGEGSQFTLFLPEAINK"
     gene            complement(11823..12545)
                     /locus_tag="TV191_000733"
     CDS             complement(11823..12545)
                     /locus_tag="TV191_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003104099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1507267.1"
                     /translation="MTKRVLLVDDEEPILRLLDYHLAKEGFVTEMVTDGRTALALAER
                     EPYDFIVLDIMLPQLDGIEVCKRLRAKGSKTPIMMVSAKSDEFDKVLALELGADDYVT
                     KPFSPRELLARVKAILRRTEAEISGDGEERREPFYTMSQLRLYPERHEVYKDKELLPL
                     TPKEYELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKAP
                     QYIQTIRGYGYKFKELKNDRTS"
     gene            12717..12872
                     /locus_tag="TV191_000734"
     CDS             12717..12872
                     /locus_tag="TV191_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507268.1"
                     /translation="MAITHKKNDQLEKMMAGFASIPDFDKPLELNQDGKLVTEKPKPQ
                     VKTAKQD"
     gene            12913..13815
                     /locus_tag="TV191_000735"
     CDS             12913..13815
                     /locus_tag="TV191_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEL1507269.1"
                     /translation="MSLFSNLPPSVLQWFAIFLSIIIEALPFVFLGTILSGCIEVFVT
                     PDLVQRYLPQNKWLRILFGTFIGFVFPSCECGIIPIINRFLEKKVPSYTAVPFLATAP
                     IINPIVLFATYSAFGNSLRFLMLRLLGAILVAVSLGIMLAFIVDENILKESTQPVHCH
                     TYSHESLPKRLYLALAHAIDEFFDTGRYLVFGTLIASAMQIYLPTKVLTAIGHSPLTA
                     ILVMMLLAFILSLCSEADAFIGASLLSTFGVAPVLAFLLIGPMVDIKNLMMMLNSFKG
                     AFIVQFISVSAVMITIYCLLVGVL"
     gene            13815..14630
                     /locus_tag="TV191_000736"
     CDS             13815..14630
                     /locus_tag="TV191_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEL1507270.1"
                     /translation="MIRFLILAGYFELTMYLELSGKLNQYINIRYAYLAYISMVLSFI
                     LALVQLYTWTKNIKLHSHLKGKVAQLTSPLILVFPVLVGLLVPTVSLDSTTVAAKGYT
                     FPLAAGASKTGVSDDGTTIQYLKPDTSLYFTKSAYQKEMLNELKKYQGKSAITITTDN
                     YMEVMELIYLYPDEFVDRTIQYTGFVYNEPGHDSYQFLFRFGIIHCIADSGVYGLLTT
                     GNQESYANNTWLTVKGQLHMEYDKTLEQQLPVLQIEEAHQAPEPDNPYVYRVF"
     gene            complement(14815..16236)
                     /locus_tag="TV191_000737"
     CDS             complement(14815..16236)
                     /locus_tag="TV191_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000643228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEL1507271.1"
                     /translation="MVCFPKDFLWGGAVAANQVEGAYLTDGKGLSVQDVLPEGGLGDY
                     TAEPTAANLKLEAIDFYHRYKEDVALFAEMGFKVFRTSIAWSRIFPQGDETEPNEAGL
                     QFYDDLFDELIAHGIEPLVTLSHYETPLHLAKVYNGWTDRRMVGFFERFATTVMQRYK
                     NKVKYWLTFNEVNSILHMPFTSGAIMTPKEKLTPQELYQAIHHELVASASVTRLARLI
                     NPAFKIGCMILAMPAYPMTSDPRDILAAKQFEQRNLLFSDIQVRGKYPSYAKSFFKEQ
                     HIDIQFEPGDSELLAQHTVDFLSFSYYMSVTQSHHPDHYQRGEGNILGGLVNPHLPSS
                     EWGWQIDPIGLRITLNDYYDRYQIPLFIVENGLGAKDKLVQTKDGHWTVQDDYRIDYM
                     RQHLLQVAKAIEDGVDIMGYTSWGCIDCVSMSTAQLSKRYGFIYVDRHDDGSGHLTRY
                     KKKSFAWYQRVIETNGRSLSEES"
     gene            complement(16263..18125)
                     /locus_tag="TV191_000738"
     CDS             complement(16263..18125)
                     /locus_tag="TV191_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HEL1507272.1"
                     /translation="MTYQETAKAIFEAVGGEQNIQEVTHCITRLRLVLKDDKQVVDQK
                     IKLIPNVIGVMRQNGQYQIILGNDVNNYYKAFMTLGQFHETDMSSSAGQKQSMIEGLI
                     ETIASVITPLIPALLGGGMLKVVGILVPMLGLAGTDSQTVAFINFFGDAAYYFMPIMI
                     AYSAAARFKVTPVLAATVAGILLHPAFVTMVATGKPMALFGAPVTPASYGASVIPILI
                     MVYLMQYIEREVNRFVPSVMKSFLQPTLIIFISGFLALVVIGPLGVIIGQGLSNSLLA
                     IYHIAPWLALAILGAIMPLVVMTGMHWAFAPIFLAASVATPDVLILPAMLASNLAQGS
                     AAVAVACQSKQKQTRQVALAAGLSALLAGITEPALYGITLKFKKPLYAAMISGGLVGA
                     YIGFVNIASYTFVVPSLIGLPQYISPTSSANFTNALIAAGLTIALTFTLTWFFGIDEE
                     VDQEGSADSDSTPVKSGLSAKQSIYAPMVGTVLPLSEVPDETFSSKLLGEGLAILPNE
                     EYVYAPFDGEVITLFPTKHAIALKNAKGVDVLIHVGIDTVELKGQGFEQLVKAGDTVK
                     QGQPLLRIDLELIGSKGYSLVTPFVVTNSSEQLEIIVNDNKEHITQHDVALVIL"
     gene            complement(18130..18969)
                     /locus_tag="TV191_000739"
     CDS             complement(18130..18969)
                     /locus_tag="TV191_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEL1507273.1"
                     /translation="MIIKRVLNHNAAISTNHQGLDILLMGKGIAFKKRIGDHIDSEAI
                     EASFVLKNSDNMNRFTELFIAVPQEVVACSERLINLGKIKLGKNLDEILYINLTDHIH
                     SAIERHKQGMIISDPLRWEIRRYYPDEYAIGVKALEVIASELGVALAVDEASFIAMHF
                     VNASLDNPFKEPHRMTEIVSYIEQKVKADFKTELDEVSIDYYRFITHVKLFAQRVLSG
                     MAYDDDETDLLLMVKDKYPEEYHCVRQISHHMKKAYHYQLSSSELLYLTVHIKRLVKN
                     VKE"
     gene            complement(19258..20715)
                     /gene="ftsY"
                     /locus_tag="TV191_000740"
     CDS             complement(19258..20715)
                     /gene="ftsY"
                     /locus_tag="TV191_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEL1507274.1"
                     /translation="MGLFERLFGKKDKTKVAEQEAATTEVLSEDITSKDTIESEKEAL
                     SDTNAHAVAADVVSRTDDTSKQAELSDEAASEQAEGLDPAARGAFLLEREPELELAAT
                     DDKTLDQAGESLSQHEAMEEAKHDRAKSEHSNESADASTEDQAETNAEYQVAAQAPAG
                     SADQPAEEGQKQETLSAESDQEKYKRSLKKTRTGFSARLNSFFANFRRVDEDFFEDLE
                     ELLILSDVGVHVATTLTEELRYEAKLENAKKPEALKRLIIDKLVAIYEGDGRYNEAIH
                     YQPGLTVMLFVGVNGVGKTTSIGKLAYRYKQEGKKVMLVAADTFRAGAVAQLVEWGRR
                     VDVPVITGPEKADPASVVFDGVERAVAERADILLIDTAGRLQNKDNLMAELEKIGRII
                     KRVIPDAPHETLLALDASTGQNALSQAKEFSKITPLTGLILTKIDGTAKGGIVLAIRQ
                     ELDIPVKLIGFGEAIDDIGEFHSEDFMKGLLEGIL"
     gene            complement(20715..21542)
                     /locus_tag="TV191_000741"
     CDS             complement(20715..21542)
                     /locus_tag="TV191_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL1507275.1"
                     /translation="MTRIKLLALDLDGTLYNTEKIVSDENKKALAAAKEKGVKVVITT
                     GRPLKAIGNLLEELDLLGEENYSITFNGGLVQRNTGHILDKSALSLAEVYDIHQQLAA
                     VGLPTDVISDGTVYSLSGNDGRRSQYHLASPLLNFVSLKSFAELPKDITYNKIVTVTD
                     PKVLDQQLARLPKTIFEDFEAFKSRDIIFEIMPKGIHKAFGLDLLCQHLGLEAKHVMA
                     MGDEANDFSMLQWAGLGVAMANAVDQAKEVADAVTTLTNDQSGVAEAIWKYILNEEG"
     gene            complement(21543..22340)
                     /locus_tag="TV191_000742"
     CDS             complement(21543..22340)
                     /locus_tag="TV191_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL1507276.1"
                     /translation="MVKLIATDMDGTFLREDGTYDKERLAALLPKLREKGILFTVSSG
                     RSLLAIDHLFEPFLDDIAIIAENGSVVQYKRDILFADVMTKQQCHDIVEKILANPYYN
                     QSGILFSGQKAAYVLKGATEDYIQKMHYYYENVQLIDCLQDIVDDTVFKASTTFTGET
                     VLAGSDWLNQELSYASAVTTGFDSIDIILKEVHKGFGMDQLCQHLGILPEKTIAFGDN
                     LNDYQMLSFAGQAIATENARPEIKAISDQVIGHCNDSAVLTYLEGLV"
     gene            complement(22858..23367)
                     /locus_tag="TV191_000743"
     CDS             complement(22858..23367)
                     /locus_tag="TV191_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507277.1"
                     /translation="MKKKAYMTLILLIGILAIFLVGKQVIKKENPNKPTVDLTVYTIS
                     SSDTQKWNKVRQLETEEAIYLIRVKEAASSEEIFSNIIADGAAMGFGVSEEDVKQFNN
                     HLENTIEDSKNNKLIEMEFFDFSNNNKGFVVANFDYGKKEFNAQKKEKKALYKKLYEA
                     FKEKNHQSR"
     gene            complement(23364..23987)
                     /locus_tag="TV191_000744"
     CDS             complement(23364..23987)
                     /locus_tag="TV191_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1507278.1"
                     /translation="MAIEVLNVTKKFGSKKIFTDLNLTFEAGKSYALIGGSGSGKSTL
                     LNIIGRLEKIDSGKVLVDEQDIWKTKERTFFKTIIGYVFQNYSLIENKTVYDNLRLIN
                     KDKKIIADVLEKVGLSNDYLNQKIYELSGGQVQRVAIARMLMKPRKIILADEPTGALD
                     SEIGKEIINLLLSETAENKYVIIATHDPAVYNKVDVIIDLKDIGSEI"
BASE COUNT         6907 a         5676 c         4475 g         6962 t
ORIGIN      
        1 aacgagaagc cttcaaaaaa aaagatgaca accatcagct tttatggtaa aatggttggg
       61 tatcttacgg gaaaggagag gactatgcct acaccattgg agcagcggca gctcaagcag
      121 cagaagcaag agcaggtctc gcagcaaaaa tttcaagagt ttcaagacct caatggacac
      181 agtagcaagc tcaaggaact tatttttttt gcccgtattg ctgtttttag tttaatcact
      241 gtcttgtttg catttgtcct tcttgtcatg aatttggcac cggtttgggc ctttctaatt
      301 gctagtgcta tcagcctagc catcacttcc tttctttcaa aggccatcac gttattaatg
      361 tcataaacag ttagagcttg gcttcgctaa gctctttttt cattactctt attgcctatt
      421 ttcttgaata aacgagtagc ccacatcaca aaaggccctc catagctgag agagccctta
      481 tttttgcctt attattcttc agacttattg ctagctgctt ctttttctga atcatcttca
      541 ggatagttga taataatatc ctcttcatcc agatcaataa tcacatcatc agccttgtca
      601 tgctctgaag cagcttcctt tgcctgatga acaaattggc tggtcttttc cttgataaaa
      661 tcaaacacct gatcagtggt catatcccct gattcaaacc tggtttttaa atcattaaag
      721 gtatggcgag ccagctgact gtactcactt cctttttctt tagccatttg atgatattcc
      781 tcaggatttt gacgataggc ttcataggcc ctttgtgcgc gagccttcaa gacctttcct
      841 ttttcagttg acaagaaata agcggtagct gctcctgaag ctacaccaat caccaacgtt
      901 ttaaaaaaat tactcatgac cttttctcct ttttaccaaa taatttagaa gcgaccttgc
      961 cgacaagagc tactttaccc acctttgcag cattgcttgt ggcatttgtc gcccgacgtc
     1021 caaggtgtct ggcctgcaca ttcaaatcag aaacactttc tgacaaatct gcaatagcaa
     1081 caaagagagg atctattgtt gtcatcttac cattcacatc atctaccagc acattagcct
     1141 tagctaatat ttcattggtt tgataaaggg taacattgac atcactcgtt aaaacggtaa
     1201 tggttttttt agcctcatca actgcctctg acaccttttt taacaccaca atcaaaaaaa
     1261 taaccagagc aacaaaggct aatgcgatta tcagcaatga aatgcccact aaattcataa
     1321 acgtctcctc tttctatccc tattcttgat aataagaaat tcccttttgt cgatgccttt
     1381 taaagataaa aacaatcgca atgataatga gcagcaccga catgtattga gaaacacgaa
     1441 ttcctaaaag catcaggctg tccgttcgca tgccctcaat caccaatcga ccacagccat
     1501 accaaatcag gtaaaatgag ataatatccc catctactaa tgacctgggc ttacgccgcc
     1561 acaccatgat aatgacaaag ccaatcaggt tccacatgga ctcatataaa aaggtgggaa
     1621 cacgatagct gccatctata aacatctgct ggcgaataaa actaggcagg taattgagct
     1681 ggctgacagc cctgccatag gcctcttggt taaagaaatt tccccatctg ccgatggcct
     1741 gagcaagcat gacactaggc gctgcaatat ctaagaaatg gataggattc agcaccttat
     1801 agtagcaata aacaaagaga acaatggtac ctgttatcaa gccgccatag atggcaatcc
     1861 caccattcca aatagcaaag atatcactca aatgctgaga ataataggac cattcaaagg
     1921 ctacataata gattcttgct ccaataattg ccaaaggaaa ggcaatcaga ataaaatcaa
     1981 taatatcatc actggtcatt ttttttcgcg gggcttcttt ggctgccaaa taaaccgcta
     2041 aaagtaatcc caccaagata caaaccgcat accagtgaag actaagagga ccaagcttaa
     2101 aggctattgg attgatcatt tgccctcctc atttttgctg attaaacgtg taaggcgctc
     2161 ctcaaaggtt ttggtagcat caaagcccat ctctttcgca cgatggttca tggcagcagc
     2221 ctcaataacc actgacacat ttcgacctgt tttgacagga atgcgaatcc ttggaatact
     2281 gacaccagaa aaggtaatct cttcattgcc attgcccaag cggtcaaaga ccttgccagc
     2341 ctcaaaattc tccaaataaa tagccaactg cacctgtgag gaatccttga cagcactagc
     2401 accgtacagc gacatgacat caataatgcc aacaccacga atctcaagga gatgacgtaa
     2461 aatctctgct ggctcccccc atagcgtctc ctcatcttta gcaaagacat ctactcggtc
     2521 gtctgccacc aagcgatggc cacgcttgac caactctaag cctgtctcac ttttaccaat
     2581 acctgaatca ccttggatca gcacccccat accgtaaata tccatcagca ccccatgcac
     2641 acttgttcgc tctgctaagg aagcatcaag aaaataagac atctcaccag ctaagcggct
     2701 ggtagatacg cggctgctaa acagagcaat accttcctcc tgcgctgcct gaaccatctc
     2761 ctctgggata gctaggcccc tagatacaat cacagctggc gtgtcttttt taaacatttc
     2821 ctttaagact gagtagcgat tgtgtgaggt catctgagtg aggtaggacc attctttcat
     2881 gccaaacagc tgaagccgct ctggggcata gtaatcaaaa tagccggtca tctcaagacc
     2941 cggacgcgaa atatctgagg tcgttatctc cttttctagc aagtcatcag ttgcatagac
     3001 aacgtcaagc ttgacctttg tgactaacat cttaacggta actgtcataa tttctccttt
     3061 tttaatatta tatcataaat cactatctaa gcccttacaa atacttattt ttcaaagaag
     3121 ctttcaaagt gcttgatcat actaaaaaag aatcctgcaa cagctgcctc aggctcactt
     3181 aaagcaggca ctagcctaaa gcggacaaac aacaaaaggc cctatctcat cagataaagg
     3241 cctacagcca gctttatttc tgataatcac gctagaggca ctattaaaat tcctgtcaag
     3301 cttttaatag tcgctcgctg tggtcttacc aaaaccagcc ttcatcttca tcatttagga
     3361 catcagcatc cttgcgacgt cttggtcctc tcccgtaacg ttcttcaagt aggtcctctt
     3421 tatatggtag gaagatggct aaaagaatat aaataacaac cccaaagcga gtaaaataga
     3481 tcaataaggc ggcaagcaca cgagctaggg gcaaatccca gccgtattta tcagctaaac
     3541 cagagataac tccagccact agcttatgct ttcgttgctt ataaaattta gattccatgt
     3601 ctcctcgcct ccttattcta tgatactagt ttattccttt tttagcaaaa taaaatcagc
     3661 cttacgactg atttttttca atgagcctgc catgacacct gccgcaggca aataccgcca
     3721 gattgatagg acgttttcgg tcataagctt ggccgcaatc ttgacagatg tagaggtaat
     3781 tagcttgatg tgactgtaat tttggagcgt atctcagacc gtctacttgg tctagaagct
     3841 ccttaaaggc ttgatcctta tgccgaaagc ccagcccctc aaaatagagg tgataatgac
     3901 aaagctcatg cctaacgatc tgtctaaaga cagtctcccc atgctcctct aagattttgg
     3961 gattgaaatc cagatgacca tcctttggaa aaaaacgtcc gcctgttgtt cttagtcgtc
     4021 tgttccaaga agcctgatgc ttaaagggct ttccaaaatc agctagcgag acctctctaa
     4081 cataatcagt cagactcacg aggcggcact aagcttaggt tgaccttgtg gcggtctaag
     4141 tcaaccttag aaacccaaac agtgactaaa tctccgacag aaacgacctg acttgggtga
     4201 ttgacaaagg cctcactcat ctctgaaatg tgaatcaaac cgtcctcatg tacaccaata
     4261 tcaacaaaag caccgaagtc aaccacattt ctaacagttc cctctagcct ttgaccaaca
     4321 gccagatcct ttacactcaa aatgtccttt cgaagaacag gagcttcaaa gtcatcacgc
     4381 aagtctcttc ctggcttcag caaatcagca atgatatcct tgagcgtttc ttgaccaagc
     4441 gtcaattgct ctgccatttc ctcaagatta accgcctgta atttggccct tgcaggctca
     4501 tctaagtctt taatcgcaag taattgaaag agctttttga cagccggata ggcttctggg
     4561 tgaacgcctg tattgtctaa tatattctta gcattgggaa tacgcaagaa gcctgctgcc
     4621 tgctcaaagg cctttgcgcc tagtctaggg acctttttga tctcagcacg tgaggtgatc
     4681 tctccatttt cttcacgata cctgacgata ttctcagaaa tggttttatt tagccctgaa
     4741 acatgagcca gtagggctgg actagctgta ttgatgttaa ccccaacctg attaacaacg
     4801 gtatcaacga caaaatccag atgctcagat agctttttct gactaacatc atgctggtat
     4861 tgtccgacac cgattgcttt tgggtcaatt ttgaccagct ctgctagcgg gtcttgcaag
     4921 cgacgcgcaa tagagatggc tgagcgcttt tcaaccgtca gctctggaaa ttcatggcgg
     4981 gctagctctg aggccgaata aaccgaagct ccgctttcat taacaatgac ataagaggtt
     5041 tctggaaaat cctttagcac ctctgcaaca aaggcttcac tctcacgact ggctgtgcca
     5101 ttaccaatgg caataatatc aatctgatag tcagtgatga gctgagctag agctactctt
     5161 gctgcttgaa tcttagcttg attagctggt gccaccggat agataacctg agtagttaac
     5221 agctttccag tcggatcaat caccgctaat ttggcccctg tcctaaaggc cgggtcaaag
     5281 cccagcacca tttttccctt tagtggtgaa attagcaaaa gatgacgcaa attttccgaa
     5341 aagagcttga tagcaccgtc ctcagccatt tcagttaatt ctgtgcggat acgtcgttcc
     5401 atagcaggaa caattttttt cttgattgtt tggttaataa catcatcaat ataagcattg
     5461 tgctccttaa agcgaaggct gaaaaagcgc agcattttgt ctatatgatg ctcaaaggat
     5521 acctttaata cgcctagctt ttccccacga ttgagagcta gggtcctgta gccctgcatg
     5581 ttagataccg tctcagaaaa cgcatagtaa atctgaaaga cctgcttgtc atctaagctg
     5641 gcttccttta ggctagaggt tatacggcta tacttccaaa tctcattata ggtccaggac
     5701 cttagcctgc tatcctctga catggcttcg accaaaatat caacagctcc agcaagggct
     5761 gcctgtggat ccgaaaaacc ttctgtgata aaggcctctg ccttagtttc taggtcttgt
     5821 gcattttgaa ggatcagtct agctagtcca gataagccgg cttctcgagc aatggttgcc
     5881 ttggtacgcc gcttttcctt gtaaggcaaa taaagctcct ctaggtcagc caatttatca
     5941 gctgcttcta tagcttcctt aagggcagct gttagtttcc cttgtccttc gattttagca
     6001 agaatggtgt ctttacgctc cctaagctgt gtgagggact tatccatatc aataatggcc
     6061 ttgatcacca cttcatcaag gttacctgta gcttccttac gatagcgcgc aataaaggga
     6121 atggtattac cctcagcggt aagggtaagc acttgactaa tctgttttgg ggtgaccccc
     6181 aacgcttctg aaatgttttg atgattcata ttttccataa cagttcttat tatagcacaa
     6241 agaaagaggg atagaacaag ataaaagctt tatgacaaat aagtgtcaag aaaacaaaac
     6301 ttatcttttc agatacttct aaaggctaag aaaaaacgat ctccaaacgg aaatcgtctt
     6361 ttagctactt agtggttagt caaaattaag tgagatcttc taactcttcc aactcctttt
     6421 caaacttatt ataaagttca tcaatttcac ttactgattt tgctgcacct accctagctc
     6481 tgaattgtct gttataagac ctaaagccat cctctcctag tttatgctta aatcgtgtta
     6541 acagattaag gatttgcagt cttgaccccc agcgcgctgc actaagcgac ttggtgtcgt
     6601 taatcgtatg ctctataaca tgcccacgag aaaacgcctc tacttttgtt gtgctaactg
     6661 ctactgttgc taaggctagc gctgcagcac tagttaatag taattttttc atgatatgac
     6721 tcctatttgt ttttttatgt agttattata taatattaat aagattatag tttactaata
     6781 tatatatata tatatttcta ataccagtaa cctttgtctg aaaatagcta gatcgtgctt
     6841 atcaaagaaa gcaaaaaagc ttcactctac aggaagtaag agagaagctt ccacgctaat
     6901 aggatactga tctgacatca tcaaaacacc aattgaggag agatttagcc ctcattccaa
     6961 ttgctctttc atcgcctagt ccttttctta tccgaagcgt ccggaaatat aatcctctgt
     7021 acgcttgtcc tttggctttg taaatagttc agctgtatcg ccaaattcac aaatatctcc
     7081 tgtgaggaaa aaggctgttt tatctgacat gcgtgaagcc tgctgcatgt tgtgggtaac
     7141 gatgataatc gtgtaatcct gctttaattg ctgaaccaag tcctcaattt ttaaggtaga
     7201 aatgggatca agagcagagg taggctcgtc catgagcaac acatcaggtg ctacagcaag
     7261 cgctcttgca atgcaaagcc gctgctgctg tccacctgat agggacatgg cactcttttt
     7321 taagctgtct ttgacctcgt cccaaatggc tgctcctctc aaggactgct ctaccagctg
     7381 atctagagtt ttcttgtcct taaggccatg tgtcctagga ccataagcca cattatcata
     7441 aatagacatg gcaaatgggt tgggctgctg aaagaccata ccaacacgct tacgcagact
     7501 gttgaggttt attgctttag catagatgtc ttgattgtct aagagaacct ctccttcgat
     7561 acgacaggaa ggaatcaagt cattcatgcg atttagggtt tttaaaaagg ttgatttgcc
     7621 acagccagag ggacctatca gggctgtgat ctgattttct ggtatgtcaa tggagatatc
     7681 ctttaaggcc tgaaatgctc cataaaagac attaagctgc ttggttgaaa aagctcccat
     7741 tttagacgac tcctttcact aatcggcgtg ataataagct tgatagggca ttgatcagca
     7801 agacagttat gagtaagata acacccgttg cataagcttc cttgacatgt agcccttcgc
     7861 tagacagcat gtacatgtga agagctagtg agcgtcctga tgacatgagg ctggttggcg
     7921 tattggtaga ggtgcctagg gtatacatca gggctgctgt ctcacccaca acacgtccaa
     7981 tcgctaggat taccccggct agaataccag gcattgcagc cggcagcact attttaaaaa
     8041 tcgtccttag cttacctgct cctaagccaa ggctagcctg acgcaagtga tcactaacag
     8101 agaggagcgc ttcttctgtt gatcgaatga taactggcaa caccatgatt acagacgtca
     8161 gaatacctga taaaagagaa tattgcaggc cgaaaaaaac cacaaagaac agcatgccaa
     8221 aaagaccaaa aacaatcgaa ggaatccctg atagcgtatc agctgcaaga cgtattgccc
     8281 ttacccatag tgagtcctgc ttagcgtatt ccacaagata gaagccagca aagacaccaa
     8341 tgggcaaggc tagcactaag gtgcctaaaa ctagactaac agttgagata atcgacggca
     8401 ttagagaaac attgtcagag gtataggtcc atgaaaataa ggataacgac agactaggca
     8461 agccttttat cagcataaag gcaataatca aaaataagga gccaaaggtc aatagcgaca
     8521 aaagatagac cagggctttt agtaaatagt tagtcatgag ctgattttcc tttcacataa
     8581 gcaaagcaag cattaatgat gagaataaag ccaaagagga cagccgatgt tgcaatcaag
     8641 gcctctctat gctgaccaga agcatatgcc atctctagga caatatttgt cgtcatggtt
     8701 cttgtgccct caaataatcc tgatggcagc acaggctggt ttcctgctac caaaataact
     8761 gccatcgtct caccaatggc acgaccaaat cctaaaataa gagcggaaaa aaggccggat
     8821 ttggctgctg gcaggatcac tcgaaaaata ctcctttcat gactggctcc cagtgcaaga
     8881 ctagctgaat aataagcctt tggaacagct ctgatagcag actctgaaag actgataagc
     8941 gttggcaaaa tcatgattcc taagagcaag gaggcagtca gcacactcat gccattacca
     9001 gcaaagctcc taatccaagg cactagcact tgaagaccaa aaaagccata aacgatagac
     9061 ggaatggctg ccatcagatt aacagctgac tttaaaaagc catagcatgc tttaggacaa
     9121 tagtaaacca taaaaactga ggtcaatata cctgttggca caccaatcac cattgcacca
     9181 agtgtgatga caaaagaccc tgcaatcatc ggcaaaatac catagcttgc cggctgattt
     9241 gacggtgacc aatcatttcc tagcaaaaag gctctcatac catacttagc aataaaggga
     9301 aggccattac taaaaataaa gatacagatt aaacaaatag caataattgc catcgctgca
     9361 ctgagaaaga agataacttt aaaaaaatcc tctttaaagg cttgtttatt cactgatgat
     9421 cctttctaag aaaggaaagc aagaacaaaa cacctcttct ttgccttcct tctaatcgtt
     9481 ctttatttga ctttgtccca gcttgttagc ttgccgctaa agacatcagc cagcacatct
     9541 atgccaatat tacttacctt attgtccttg tgaacaatca ctacgatacc atcaagggca
     9601 atcgcatcat caattaagcc cttgctctcc tcagttgtta ggtcacgaga aaccataccg
     9661 atgtctgctg ttttttcctt gacggcggtg atacctgctg atgagccatt tgaggtaata
     9721 tcaatgctaa tggctggatt ttctttcttg tatgcttctg ctaatttttc catcaagggt
     9781 gaaactgagg ttgagcctac aattgacagc ttgcctgata agcccttact gctataggct
     9841 ggcgcgtctg tttttgcttc gatcaatcga ttgtctctaa caatctcctg cccctgcttt
     9901 gagtcaataa aggtgataaa atccttacca actcctgata ggtctgagga ccatacaata
     9961 ttaaagggac gctgcagagg gtatttcccc tctaaaatag tctcacgact agcctttacg
    10021 ccatttacct ttagggctgc aacgtcgcta tttaaggacc ctagcgagat gtagccaatg
    10081 gcacgactat ttcccttaac agaggagatg accccttctg tgctattttg gataatagct
    10141 gtttttgctg tttggtcaat ctctttgtca ccgtcctttt ttagaatgcc tgtcatttcg
    10201 gtaaaggctc cacgagtacc tgagccattt tctcgagaaa caaggtcaat cctgtctgct
    10261 gcttttccag catcagcact gttattgcca caggctgcaa gacctaagcc tgataagcca
    10321 atagctgcca tgatcagcat ttttttgatt gtcataagaa tcacccttat cttttatgat
    10381 attgtgttgt aggcttgcta cacctatagc ttatcaggtc tttgtaaagg tttatccctg
    10441 attaatgtaa agattttgta aaacctaaaa cagccactac caaggctggc cttaagtagc
    10501 tggtagtgac tgtttacttg ttgatagctt ctggtaagaa taaggtaaat tggctgccct
    10561 ctcctagctg acttgtgact gttatctgac cgccaagaag ctgactcagc tcctttacaa
    10621 tggctaggcc taggcctgtt ccaccacttt gcctgctacg tcccttgtta acacgataaa
    10681 agcgctcaaa aatacgatct agctcaattt ggctaatgcc aatcccagta tctgcaactg
    10741 taatggcaac accaccagca accctttgac tggatagctg aattctgccc ccattgtctg
    10801 tatactgtat cgcatttgat aagagattta acatgatctg cgataagagg tattgatcag
    10861 atgtcacaac aatcgaatcc tccaatgcat agcttagctc aagctgcttt tgctctagct
    10921 gtggcctcat gctctgacct gtatacagca ggaagttcct gagctgaaac tctgtcaggt
    10981 caagtggtgt cttgttagcc ttggataagg tcagcaggtg ctcaacaata cgttctagac
    11041 gcaagctttc attgtagata atgtctaaaa agtcttcttt taggcttgtt tcatcgtcag
    11101 gcatttcctt aatcgtttca gcaaagccct tgatcgatgt aaccggtgtt cttaattcgt
    11161 gagaagcatt agcaataaac tccaaattta gcctctcata atgacgaatg gccgtcagat
    11221 catataagag cactaaaatc tccttgacaa catgcgactg gttaaagata ggcacaaggg
    11281 taacctccaa gatcaaatca ccatcatgta ggcctgttaa ttccttcttt aatgtctgct
    11341 tttggtcaaa gacttgatta actaaggcta tcagatccat tcgtttaaga tcctccaaga
    11401 ccacaaaagg tggcttagcc tctggaaaat aagccggtaa ggatttgctg gtcagcaaca
    11461 gctccctttg attggagact aaaagcatgc ccatcgtgag atgagaggtt acagcctcca
    11521 cattttttga taaggctttt agccttgctt ccttttgtaa taggtcactt tttagctctg
    11581 tcagctgctt agcataagca cttaaatcag cctgccccac taggagaaaa tggtcactag
    11641 ctgtcaaaag atggtggtgc aaggctctga attcacgctc ccatctaaat agcatgctca
    11701 agacataaaa gctagctacg agaccagtac acagcactac tagagtcagc acctgatgcg
    11761 gcccttgcca aatcagacca agagcagcca gcaagcaaag ccctagcagc atgctcaaac
    11821 gcctaagatg tcctatcatt ctttagctcc ttaaatttgt agccatagcc gcgaatggtt
    11881 tgaatatact gaggcgcctt aggattgtcc tcgatttttt ctctgagctt gccaatatga
    11941 acgtctacca gacgtgtttc ttggccaaag tcataacccc agatacgctc taatagccgc
    12001 tcacgcgtca gggtcatatt agggtgcttc atgagataga gcagtagctc atattccttt
    12061 ggggttaacg gcaatagctc cttgtcctta tagacctcat gtcgctctgg gtacagacgc
    12121 aattgactca tcgtataaaa aggctcacga cgctcttcac catcaccaga aatctctgct
    12181 tcagtacgcc ttaaaatagc cttgacacgc gctaataatt ctctaggact aaagggcttg
    12241 gtcacataat catctgcccc cagctccaaa gccaaaacct tgtcaaattc atcactttta
    12301 gcagaaacca tcataattgg ggttttgctt cccttagcac gaagcctttt gcagacctcg
    12361 ataccgtcta attgcggcag cataatatct aacacaataa aatcataagg ttctctttca
    12421 gctaatgcca aggcagtacg gccatctgtt accatctctg tcacaaagcc ctccttggcc
    12481 aagtgataat ccagtagcct taagataggc tcctcatcat ctactaataa tactcgtttt
    12541 gtcatttcat agctcccatc agccacatta tatcatattt gtcagtcaat ctaatgacac
    12601 actgcttgac ggcctgaagc ctaaaatcaa tcagaagata aaaagatgtt ttagctttgg
    12661 ctttaccgtc aaatgattgt ataatagagc tatattgatt gaaagaaggt atacctatgg
    12721 caattactca taagaaaaat gaccagctcg aaaagatgat ggcaggcttt gcgtctatcc
    12781 cagattttga taagccttta gagcttaacc aagatggaaa gctagtcact gaaaaaccaa
    12841 agccacaagt caagacagct aagcaggact agcccttatt ggcgtcgtta acatatagaa
    12901 aggatacggt gaatgtcgct tttttcaaat ctgccaccca gcgtgcttca atggtttgcg
    12961 atttttctat ccattatcat tgaagccctg ccttttgtat ttttagggac tattttatct
    13021 ggctgtattg aggttttcgt cacgcctgat ttagttcaaa gatacctccc tcaaaataag
    13081 tggctaagaa ttttatttgg tacctttatt ggctttgttt ttccttcctg tgaatgtggt
    13141 atcattccta ttattaatcg ttttttagaa aagaaggtgc ctagctacac tgctgttccc
    13201 tttttagcaa ccgctccaat tattaatccg attgttttat ttgctaccta ctctgccttt
    13261 gggaattcgc tgcgctttct catgctaagg cttttaggcg ccattttagt ggctgtcagc
    13321 cttggcatca tgctagcctt cattgttgat gagaacattc tcaaggaatc aacccagccg
    13381 gtgcattgtc atacttacag tcacgaaagc ctgccaaaac ggctttactt ggcactggct
    13441 cacgctattg acgaattttt tgatacagga aggtatctag tctttgggac cctgattgct
    13501 tcagccatgc agatttatct gccaacaaag gtgctgacag cgatcggaca tagccctttg
    13561 acagccatct tagtcatgat gctcttagcc tttatcttat ctctttgcag tgaggctgac
    13621 gcctttattg gagcttcgtt attgtcaacc tttggagttg ctcctgtttt agcctttctc
    13681 ttaatcggcc ctatggttga catcaaaaac ctcatgatga tgctcaattc ctttaaggga
    13741 gcctttattg ttcaatttat cagtgtatca gctgtgatga ttaccatata ttgcttactt
    13801 gtgggggtgc tgtgatgatt cgctttttaa ttttagcagg ctattttgag ttgaccatgt
    13861 atctagagct atctggcaag ctaaatcaat atatcaatat tcgttacgct tacttagcct
    13921 atatttctat ggttctatcc tttatccttg cattggtgca gctatacact tggactaaaa
    13981 acatcaagct acacagtcat ttaaaaggta aggtcgctca gctgaccagt ccccttatcc
    14041 tggtctttcc tgttttggtt ggcttgttag tacctacagt cagcttggat tcgacgaccg
    14101 ttgccgccaa gggctatacc tttccattag ccgcaggcgc ttcaaaaaca ggggtcagtg
    14161 atgatggtac tactattcaa tacctaaagc cagacaccag cctgtacttt accaaatccg
    14221 cctatcaaaa ggaaatgctc aatgaactga aaaaatacca aggcaaatca gccatcacca
    14281 ttaccactga caattatatg gaggtaatgg aattaatcta cctttaccca gacgaattcg
    14341 ttgatcgtac gattcagtac actggctttg tctataatga gccaggacat gacagctatc
    14401 aattcctctt tagatttggg attatccatt gtatcgctga ttccggtgtg tatgggcttc
    14461 tgaccactgg taatcaagaa agctatgcca ataacacttg gctgaccgtc aagggccagc
    14521 tgcacatgga atatgacaag accctagagc agcagcttcc tgtccttcaa atcgaggaag
    14581 cacaccaagc cccagagcct gataaccctt atgtctatag ggtattttaa caagcattaa
    14641 gcctccacac ctatgacaca ggtctatgga ggctttttgt taggggacag tacaaagacg
    14701 taattgagtt cgttccattt aaatgaaatg gctaaaagcc gtatagcatc agccttttaa
    14761 aagacgtgtg ctatacggct ttgctattgt tggtaaagcc tttgaggcta ctttctagct
    14821 ctcctcagac aggctacgcc cattggtctc aatgaccctt tgataccaag caaaggattt
    14881 tttcttgtag cgtgtcaaat gaccactgcc atcatcatgt cggtcgacat aaataaagcc
    14941 ataacgctta cttagctgag cagtcgacat agaaacacaa tcaatacagc cccaggaggt
    15001 atagcccata atgtcaacac cgtcctcaat agccttagca acctgcaata aatgctgcct
    15061 catgtaatca atccgataat cgtcctgaac tgtccagtga ccatcctttg tctgtactag
    15121 cttatctttg gcgccaagcc cattttctac aataaagaga ggaatttggt acctatcata
    15181 gtaatcattc aaggttatgc gaaggccaat tggatcaatt tgccagcccc attccgaaga
    15241 gggcagatga ggattaacca agccacctaa aatattgccc tcccctcgtt gataatgatc
    15301 cgggtgatga gactgagtca cactcatgta atagctaaag gataaaaagt caaccgtatg
    15361 ctgcgccaaa agctcactgt cgcccggttc aaattgaatg tcaatgtgct gctccttaaa
    15421 aaaggatttg gcataggaag ggtattttcc tctgacctga atatctgaga acaggagatt
    15481 acgttgctca aactgcttcg cagctaaaat atccctcgga tcagaggtca ttggataggc
    15541 tggcatagcc aaaatcatac agcctatttt aaaagcaggg ttaatcaatc tagcaagcct
    15601 tgtcacacta gcagacgcta ctaattcatg gtgaatcgct tgataaagct cctgcggagt
    15661 cagcttttcc tttggtgtca tgatagcacc actggtaaaa ggcatatgca ggattgaatt
    15721 aacctcattg aaggttaacc aatacttaac cttgttcttg tagcgctgca tgacagttgt
    15781 cgcaaaacgt tcaaagaagc caaccatacg acggtcagtc cagccattat agaccttagc
    15841 tagatgcagt ggggtttcgt agtgagatag ggtcactaaa ggctctatgc catgtgctat
    15901 cagctcatca aacaaatcgt cataaaattg tagccctgct tcgttaggct ctgtctcatc
    15961 gccctgagga aaaatacgag accaagcaat tgatgtccgg aaaaccttaa agcccatttc
    16021 tgcaaagagc gccacgtcct ccttgtagcg gtgataaaaa tcgatggcct ctagcttcaa
    16081 attagctgct gttggctcag ctgtatagtc tcctaagccc ccttctggta aaacatcctg
    16141 aaccgacaag cctttgccat ctgttaaata agctccctca acctgattgg cagcaactgc
    16201 ccctccccac aagaaatcct ttggaaaaca aaccatatta tctcctcctt caattcatct
    16261 ctttagagaa taacgagagc aacatcatgc tgagtgatat gctccttgtt gtcattaaca
    16321 atgatttcga gctgctcaga gctattggtc accacaaatg gagtcactaa agaatagccc
    16381 ttagagccaa tcaattcaag atctatacgt agcagcggct gcccctgctt aacagtatca
    16441 ccagccttaa ccagctgctc aaagccctgt ccttttagct caaccgtatc aataccaaca
    16501 tgaattaaga cgtcaactcc cttggcgttc tttaaagcaa tagcatgctt tgttggaaaa
    16561 agggtgataa cctcgccatc aaatggggca tagacatatt cctcattagg taaaatagcc
    16621 agcccctctc ctaaaagctt agacgaaaag gtttcatctg gcacctctga taatggaagc
    16681 actgtgccaa ccatcggagc ataaatagat tgctttgctg ataagccact ttttactggc
    16741 gtgctatccg agtcagctga cccctcctgg tcaacctcct catcaatgcc aaaaaaccag
    16801 gttaatgtaa aggttagagc aattgttaag cccgctgcaa ttaaggcatt ggtaaaatta
    16861 gcagagctag tcgggctaat gtattgtggc aatccaatta gtgatggcac cacaaaagta
    16921 taagaggcta tattaacaaa gccaatatag gcgcccacaa ggccaccaga aatcattgca
    16981 gcatagagcg gctttttaaa ctttagagta atgccataaa gagcaggctc tgtaattcct
    17041 gccaataaag ctgataagcc tgctgctaag gcaacctgac gggtttgctt ttgctttgat
    17101 tgacatgcta cagccaccgc tgctgatccc tgagctaggt tagaggctag cattgctggg
    17161 aggattaaaa catctggagt tgctacagag gccgccagaa aaataggagc aaaggcccaa
    17221 tgcatacccg tcataacaac aagcggcata attgcaccta aaatagcaag agccagccaa
    17281 ggagcaatat ggtaaatcgc tagcaggcta ttagacaagc cctgtcctat aataacaccc
    17341 agaggtccaa taacaactaa ggctagaaag cctgaaataa aaataatcaa ggtcggctgc
    17401 aggaagctct tcatcacact cggtacaaaa cggttaacct ctcgctcaat gtattgcatc
    17461 aggtaaacca taattaaaat cggaataact gacgcaccat agctagcagg tgtcaccggc
    17521 gctccaaaca aagccatagg tttacctgta gctaccatcg taacaaaagc tgggtgtagt
    17581 aaaatccctg caacagttgc tgctaataca ggtgtgacct taaagcgtgc cgcagctgaa
    17641 tatgcaatca tgattggcat aaaataataa gcagcatctc caaaaaaatt aataaaagca
    17701 actgtttgag agtccgtacc tgctagacca agcataggca ccaagatccc aaccaccttt
    17761 aacataccgc ctcccagtaa ggcaggtatc agtggagtaa tcacactagc tatcgtttca
    17821 atcaaccctt caatcataga ctgcttttga ccagcgctag agctcatatc agtttcatga
    17881 aactgtccta gggtcataaa tgccttataa taattgttaa catcgtttcc taaaataatt
    17941 tgatactgac cgttttggcg catgactcca atcacattag gaataagttt gattttttga
    18001 tctaccactt gtttatcatc tttcaaaacc aagcgtaacc gcgtgatgca gtgggttacc
    18061 tcttgaatat tctgctcacc accaactgct tcaaaaatgg ccttggctgt ttcttgataa
    18121 gtcatttcat tactccttca catttttgac taaacgtttg atatgaaccg ttaaatacaa
    18181 aagctcacta gagctaagct gataatggta tgcttttttc atgtgatggc taatttgcct
    18241 aacacagtga tattcctctg ggtatttatc cttaaccatc agcagcaaat cagtctcgtc
    18301 atcatcataa gccatgcctg ataacacgcg ctgagcaaat agcttcacat gagtgataaa
    18361 gcgataataa tcaatagaga cttcatcaag ctctgtctta aaatcagcct tgaccttctg
    18421 ttcaatgtaa gacacaattt ctgtcattcg atgaggctcc ttgaaaggat tatcaaggct
    18481 cgcgttgaca aagtgcatcg caataaacga agcttcatct acagccagag cgactcctag
    18541 ctcactggca atgacctcta aggccttaac gccaatcgca tattcatcag gataataccg
    18601 tctaatctcc cagcgcaagg gatcactaat gatcatcccc tgcttatgtc tttcaatagc
    18661 tgaatgaata tggtctgtca aattgatata gagtatttca tctaaatttt tacccagctt
    18721 aattttccct agattaataa gcctctctga gcaagcaacc acctcttgcg gaacagcaat
    18781 aaataattca gtaaaacggt tcatattgtc actatttttt aaaacaaatg acgcttcgat
    18841 agcttcacta tcgatatggt caccaattct tttcttaaaa gcaatcccct ttcccatcaa
    18901 aagaatatct agcccctgat ggttggtcga aatcgctgca ttatggttta aaacgcgttt
    18961 aataatcata aaagtcctag tccctcattg cttcacaata aaaaatgacc tatccacagc
    19021 atgctaaaag gccacactgg aataggtccc tgctcacaaa actgtgataa catcctttaa
    19081 tattctgatt catttgtcat tagcacgctt accctaagta atcacatcta ataacgtttt
    19141 cattttatca tctcctaaag gtcctgtcaa gcgttttcaa aaggctgttt gacatttgcc
    19201 tctaaacgaa ccccctcatt ctctttggcc aacagccgat aatctgaggc tttcctctta
    19261 aagtatgcct tctaatagtc ccttcataaa gtcctcagag tgaaattcac cgatatcatc
    19321 aatagcctca ccaaagccaa tcagcttcac tgggatatcc aattcctgac gaatagctag
    19381 gacaattccc cccttagctg taccgtcaat cttagttaaa atcaagcctg tgagcggtgt
    19441 gatttttgaa aactccttag cctgactcag agcattttgc cccgttgagg catcgagcgc
    19501 tagcagggtt tcgtgtgggg catcaggtat gacacgctta atgattcgtc ctattttttc
    19561 aagctctgcc attaggttgt ccttattttg caggcggcct gcggtatcaa tcaggagaat
    19621 atctgccctt tcagcaacag ccctctcaac gccatcaaag accacagagg ccggatctgc
    19681 tttttcaggg cctgtaatga ccggcacatc aacccgtcgt ccccattcaa ccagctgggc
    19741 aaccgcgcct gctcggaagg tatcagctgc aacaagcata accttttttc cctcttgctt
    19801 ataccgataa gctagctttc caattgatgt tgtcttacca acgccattca ccccaacaaa
    19861 gagcataacg gtcaagccag gctgataatg aatcgcttca ttgtagcggc catccccctc
    19921 ataaatagcc actagcttat caatgataag acgctttaga gcctctggct ttttagcatt
    19981 ttcaagctta gcctcatagc gcaattcttc agtcaaggtt gtggcaacat gaacaccaac
    20041 atctgagaga atcaaaagct cctctaagtc ctcaaagaag tcctcgtcaa cacgtctaaa
    20101 gttagcaaag aagctgttca agcgtgctga aaagcctgta cgggttttct ttaagctgcg
    20161 cttgtatttt tcctgatcag attcagctga tagggtctct tgcttttggc cttcctcagc
    20221 tggctgatca gctgaaccag caggtgcttg agctgctact tgatactcag catttgtctc
    20281 tgcctgatct tctgttgatg cgtctgcgct ctcgttacta tgctctgact tagccctatc
    20341 atgcttagcc tcctccatag cctcgtgctg gcttaggctc tcacctgcct gatccaaggt
    20401 cttgtcatca gtagctgcta actctagctc cggctctctt tctaaaagaa aagctcctct
    20461 agctgctgga tcaagccctt cagcttgctc tgaagcagcc tcgtctgaga gctcagcctg
    20521 tttgctagtg tcatcggtcc tagagaccac atcagctgcc actgcatgag catttgtatc
    20581 tgataaggcc tccttttcag actcaatcgt atcctttgac gttatgtcct ccgacaatac
    20641 ctctgtagtg gcagcctctt gctcagcaac cttagtctta tccttttttc caaataagcg
    20701 ttcaaataat cccattagcc ttcctcattt aaaatatatt tccaaatagc ctcagccaca
    20761 cctgattggt cattggttag ggtagtcact gcatctgcca cttccttagc ctgatcaacc
    20821 gcattggcca tagccacacc aagacctgcc cattgtagca tgctaaagtc attggcctca
    20881 tctcccatcg ccatgacatg cttggcctcc aagcccaagt gctgacaaag caggtccaaa
    20941 ccaaatgcct tatgaatccc cttaggcata atctcaaaga tgatgtctcg tgatttaaag
    21001 gcctcaaaat cctcaaagat agtctttgga agccttgcaa gctgctgatc caagaccttt
    21061 ggatccgtca ccgtaacaat tttattgtat gtgatgtcct ttggcagctc agcaaatgat
    21121 ttaaggctaa caaagttcag caagggactt gccaagtgat actgagagcg tctgccatca
    21181 ttgcctgata gactataaac agtaccatca ctgataacat cagtaggtaa gccaaccgct
    21241 gccaactgct gatgaatgtc ataaacctca gcaaggctta gagcgctttt atctaaaata
    21301 tgaccagtat ttcgttgaac cagaccgcca ttaaaggtaa tgctatagtt ctcttcacct
    21361 agcaaatcca gctcctcaag caaatttccg atagccttaa gaggacgtcc ggttgtgata
    21421 acaaccttaa ctcctttttc cttagctgct gctagagctt ttttgttctc atcactaacg
    21481 attttttcgg tattatagag agtcccatct aaatctagag ctaaaagctt tatacgcgtc
    21541 atttacacca atccctccaa ataagttaac actgctgagt cattacaatg accaataacc
    21601 tgatcagaaa tcgctttgat ttcaggcctt gcattttcag tagcaatagc ctgccctgca
    21661 aaggacagca tttgataatc atttagatta tcgccaaagg caatggtctt ttccggtaaa
    21721 atgcctaggt gctgacacag ctgatccatg ccaaagccct tatgaacctc ttttaggata
    21781 atatcaatcg aatcaaagcc agtcgtcacc gcagaagcat aggacagctc ctgatttagc
    21841 cagtcactgc cagctaagac tgtttctcct gtaaaggtcg ttgaggcttt aaaaacagtg
    21901 tcatcaacaa tatcctgcag acaatcaata agctgaacat tttcataata ataatgcatt
    21961 ttttggatat aatcctccgt agctcctttg agcacatagg ctgccttttg ccctgaaaag
    22021 aggatcccag actgattgta ataaggattg gcaagaattt tctctacaat gtcatgacac
    22081 tgctgcttgg tcatgacatc agcaaaaaga atgtccctct tgtattgcac cacagaccca
    22141 ttctcagcga taatggcaat gtcatctaaa aaaggctcaa acaagtgatc aatggctaaa
    22201 agcgaacgcc cactagaaac tgtaaagaga atcccttttt ctcttagctt aggcaacaga
    22261 gctgccaagc gctccttgtc ataagttccg tcctctctta aaaaggttcc gtccatatct
    22321 gttgctatca atttaaccat acaatttaac catttccttt ttagggagat actgattcag
    22381 ctattcagct ctcccaaaaa tctctttttc cattatacca tatctaaaca aaaagggcgt
    22441 gcctgtccta acacgtcctt gttttaaggc tttataattt ctgtagtggg taactccact
    22501 gtggagatta ttgagccctt attccaaggc tttctttatg ttctattgta tcaatttcct
    22561 tattccaatt tctgttgcaa ttaactttaa catacaatct aaccatttca ctttcaaggg
    22621 agtgcaaaac ccgagtgggg tgtgcaactc aaatcccagt ataactcctt tcgttatacc
    22681 acaggtagac caaaaaaggg cgtgccatct gacataccct tgttttaaca gtcaatctga
    22741 gctccgtttt taaaggctaa acttctttat ctccatactc tcaacgctta tttgccataa
    22801 ttcttaattg aagcccgtca ctaagttttc ttgttactaa agagttgagt aatgaatcta
    22861 tctagactga tgatttttct ccttaaaagc ttcatatagt tttttatata acgctttctt
    22921 ttcttttttc tgagcattaa actctttttt accgtaatca aaatttgcta ccacaaaccc
    22981 cttgttattg ttagaaaaat caaaaaattc catttcgatt aatttgttat tcttagaatc
    23041 ttctatagta ttctctaaat gattgttgaa ttgtttaaca tcttcttcac taactccaaa
    23101 acccatagca gctccgtctg caatgatgtt tgaaaatatt tcttctgaag atgctgcttc
    23161 ttttaccctt attaggtata tggcttcttc tgtttctaat tgtcttactt tattccattt
    23221 ttgggtatca ctagaagaga tcgtatagac tgttaaatct accgtaggtt tattgggatt
    23281 ttcttttttt attacttgtt ttcccactaa gaaaattgcg agtattccaa ttaataatat
    23341 caacgtcata taagctttct ttttcatatc tcactcccta tatctttcaa atcaatgata
    23401 acatcaacct tattatatac agctggatca tgtgttgcta taataacata tttattttcg
    23461 gctgtttcac tcaataataa attaatgatt tcttttccaa tctcactatc caaagctcct
    23521 gtaggttcat ccgctaaaat aattttacgt ggcttcatta acattcttgc aatagctaca
    23581 cgctgaacct gtcctccaga taattcatat attttctgat ttaaatagtc attagaaagt
    23641 cctacttttt caagtacatc agctattatt tttttatctt tattgatgag tctcaaatta
    23701 tcatatactg ttttgttttc tattaaagaa taattctgga atacataccc aataatagtt
    23761 ttaaagaaag ttctttcttt tgtcttccaa atatcctgct catcaactaa aacctttcca
    23821 ctgtcaattt tttctagtct tcctatgata ttaagtagtg tacttttacc tgaaccagag
    23881 cctccaatca atgcgtagct ttttccagct tcaaacgtta aatttaaatc tgtgaatatc
    23941 ttttttgagc cgaatttttt ggtaacattc aaaacttcaa ttgccattag tcatctcctt
    24001 ttagaatttg tgtatatttt
//
LOCUS       DARYXW010000023        23237 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.023, whole genome shotgun sequence.
ACCESSION   DARYXW010000023 DARYXW010000000
VERSION     DARYXW010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23237)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23237)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23237
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.023"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(<1..1341)
                     /locus_tag="TV191_000745"
     CDS             complement(<1..1341)
                     /locus_tag="TV191_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEL1507279.1"
                     /translation="MLTMKHKMLIFCLLLSIFVSQFHMLHVYAETSSKTQYNILIKES
                     LDTNKVKKQLNDQGMIVLDEIPEINVLTIAAANDSSMILEKNCNYIDDISRNNTFTVN
                     PKMTYQFGHAFYLDSDLNYWNKQWDMQRSISTSSRFWHKSSGEVTIGVIDSGITDNNT
                     DISSKIISVQNFTEDPVTKAIDVNNVLDKTGHGTSVVGQMSSNGYYTGIAPGMKVRMY
                     KVFEEGNAQDEWILKAIIQAAKDDVDVINLSLGQYLLKASSNIDEDRTALINSYQRAI
                     NYAHKQGSVVVASVGDEGANLNNQAELKNLVSALTGRAFSSVDGTIEDIPAQLDNVVT
                     VGSVDGDGAISNFSNRGRNVVDIFAAGGGSKKLALHGYDTWINNKLFEQDWVIIPTLE
                     GKYTYGYGTSIAAPKVAAALGLIIEKYDLKDKPDEAITILYSNSWSSLDDNGKPI"
     gene            complement(1509..1640)
                     /locus_tag="TV191_000746"
     CDS             complement(1509..1640)
                     /locus_tag="TV191_000746"
                     /inference="COORDINATES: protein motif:HMM:NF022534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507280.1"
                     /translation="MEEETKLNQETMTTMIGKYECYARQLEKLAFVFNYKSELRTKD"
     gene            complement(2749..4695)
                     /gene="thrS"
                     /locus_tag="TV191_000747"
     CDS             complement(2749..4695)
                     /gene="thrS"
                     /locus_tag="TV191_000747"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEL1507281.1"
                     /translation="MITITFPDGAVREFESGVTTFEIADSISKSLAKKALAGKFNGQL
                     IDTTRAIEEDGSIEIITADHEDAFEVLRHSAAHLFAQAAKRLFPKLHLGVGPAIADGF
                     YYDTDNADGQISNEDLPRIEEEMKKIVKENFPCIREEITKEEALELFKDDPYKVELIN
                     EHADDAAGLTVYRQGEFVDLCRGPHVPSTGRIRVFHLLNVAGAYWRGNSDNNMMQRVY
                     GTAWFDKKDLKAYLTRLEEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRT
                     LERYITDKELASGYQHVYTPPLASVELYKTSGHWEHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVYKNHVHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSYRDPKDTHKYYDNDEMWENAQSMLKAA
                     LDEMGADYFEAEGEAAFYGPKLDIQVKTALGNEETLSTIQLDFLLPERFNLSYIGADG
                     EEHRPVMIHRGVISTMERFTAILIETYKGAFPTWLAPRQVTVIPISNEAHIDYAWEVA
                     KILRDHGIRADVDDRNEKMQYKIRASQTSKIPYQLIVGDKEMQDKSVNVRRYGSKATH
                     TEAISAFVDNILADIARKSRPAEG"
     gene            complement(5286..6620)
                     /locus_tag="TV191_000748"
     CDS             complement(5286..6620)
                     /locus_tag="TV191_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEL1507282.1"
                     /translation="MRVGLFTDTYFPQVSGVATSIRTLKEELEKEGHEVYIFTTTDKH
                     VKRFEDPTIIRLPSVPFVSFTDRRVVYRGLISSYKIAKEYHLDIIHTQTEFSLGLLGK
                     MVGKALRIPVVHTYHTQYEDYVSYIANGKIIRPSMVKPLLRGYLKDLDGVICPSRIVL
                     NLLEGYEVTIPKRVIPTGIALENYVREDIKKEDVAALRKELAISDDETMLLSLSRVSY
                     EKNIQAIIHQLPAVLSENSRIKLVIVGDGPYLQALKELAVSLGVEDHVVFTGMIAHDQ
                     VGLYYKACDFFISASTSETQGLTYIESLASGKPIIAHGNPYLDDLITDKMFGTLYYAE
                     SELSDAIIDAILETPQMNQRLLDEKRYEISAQHFGKSVYTFYLDTLISRHNKETKKLS
                     LYLNRTEKSGSIKLVQGAIHLPKRAAKATALTSVKVLKAPIKLVNAIRDFLD"
     gene            complement(6622..7620)
                     /locus_tag="TV191_000749"
     CDS             complement(6622..7620)
                     /locus_tag="TV191_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEL1507283.1"
                     /translation="MKVLLYLEAENYLRKSGIGRAIKHQAKALSLVGQEFTTDPKDDY
                     DLVHLNTYGLKSWLLMSKAQKAGKKVIMHGHSTEEDFRNSFIFSNLVSPLFKAYLCRF
                     YNKADAIITPTPYSKALIEHYGVKTPIFAVSNGIDLEQYGANADKEAAFRRYFNLKEG
                     EKVVMGAGLFFLRKGIDEFVKVAEMMPDVRFIWFGDTNKWVIPARVRQIVNGKHPDNV
                     IFPGYIKGDVYEGAMTGADAFFFPSREETEGIVVLEALASRQHLVLRDIPVYEGWIDQ
                     DSAELANDTSGFVAALRRILSGESNKTEAGYRVAEGRSLDRIAHQLVAIYQKVMEL"
     gene            complement(7916..9391)
                     /locus_tag="TV191_000750"
     CDS             complement(7916..9391)
                     /locus_tag="TV191_000750"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEL1507284.1"
                     /translation="MSHQLLMQAFEWYLPADGRHWQRLKSSIPELQQLGVSQLWLPPA
                     FKGTSSDDVGYGVYDLFDLGEFNQNGTVSTKYGSKEDYLQLIAALKEAKIKPIADVVL
                     NHKANGDHKERFSVIKMNPENRQQALTEPYEIEGWTGFDFPGRQNTYNDFKWHWYHFT
                     GLDYDAKANETGIYMITGDNKGWANDELIDDEHGNFDYLMYNDLDFKHPEVIQNLQDW
                     AKWFIETTGIEGFRLDAVKHIDSYFIQTFINDIRTQLKPDLEVFGEYWKSDQESMEDY
                     LEATKAQFALVDVALHMSFFNASQQGADFDLTTIFDGSLVASRPDLAITFVENHDTQR
                     GQALESTVEEWFKPLAYGLILLRQEGKPCLFYGDYYGISGDYPQQSFKEVITKMAELR
                     QQLVYGEQIDYFDHANCIGWTCLGDDQRPQPLAVVLSNGDAGWKHMEVGQAYAGQVFC
                     DFLDNCQETVVVAEDGWADFKVEAGSISAWVLQKAQPKEEA"
     gene            complement(9461..10462)
                     /gene="ccpA"
                     /locus_tag="TV191_000751"
     CDS             complement(9461..10462)
                     /gene="ccpA"
                     /locus_tag="TV191_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEL1507285.1"
                     /translation="MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFSILAKGIDDIAAMYKYNIVLASS
                     DEDDDKEVNVVNTLFAKQVDGIIFMGHHLTDKIRAEFSRSRTPIVLAGTVDLDHQLPS
                     VNIDYKAAVADVVDILAKDHQSIAFVSGPLIDDINGKVRLAGYKDGLKKNKLDFKEGL
                     VFEANYSYKEGFELAQRVINSGATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSN
                     DSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEILLNHGIKKRGTTK"
     gene            10636..11721
                     /locus_tag="TV191_000752"
     CDS             10636..11721
                     /locus_tag="TV191_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEL1507286.1"
                     /translation="MTKLDQIRLYLNQEKAELAIFSDSVTINYLTGFLCDPHERQMFL
                     FVYHDKAPVLFVPALEVARAEQLLDFPVFGYVDSENPWEKIKSILPSTAAKTIYAEFD
                     HLNITKFQGLQSVFSGRFDNLTPYIQRMRLIKSADEIQKMLIAGEFADKAVNVGFDNI
                     SLDVTETDIIAQIEFEMKKQGISKMSFETMVLTGNNAANPHGIPGTNKIENNALLLFD
                     LGVETLGYTSDMTRTVAVGKPDQFKLDIYQLCLEAQLTALDMIKPGVTAAQVDAAARQ
                     VIEKAGYGDYFNHRLGHGIGMDVHEFPSIMAGNDLILEEGMCFSVEPGIYIPGKVGVR
                     IEDCGHVTKDGFELFTQTPKELLYFEG"
     gene            complement(11895..13478)
                     /locus_tag="TV191_000753"
     CDS             complement(11895..13478)
                     /locus_tag="TV191_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011226359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1507287.1"
                     /translation="MKSILQVISKWQLCLYSLLALLYSLQGLLLSVLIQIAGQIDMNN
                     KGMVLLFGLGGVAFFVFIYMCMYLNNILARSMVRAFNCLIAKKALYHFYHKQLNYFTS
                     ALNSFLTQDIPMFWQEYLVPLFIYPVFGLSILASVLYLLLQDIYIGIAFTIGGFLMII
                     PQFVFNHLLQSRGLELSQAREKSLASITDFTKGADTIQSNQANEAFAHHVLEMIQHME
                     DKQYSYYTTHNLVMFWTGPLKGIGLVSPLIIGLLVMSYSSLSLTTLIAMITASTNLVS
                     PLQQLLEATSSLQSATAVKEKMVRVLALEEETKHQALTPTDDLTLDIYFKRLDKYFDH
                     RLIFQGIDGHISAGHKTLLTGASGSGKSTLFALLCGEDKDYSGTIYFEAANGKRYFPS
                     YDVVSLIHQKPYIFEGSLRDNLTLFQDYSDQRLKEILQQVHLWNELNGDLDLHLDGQN
                     LSGGQIMKLEIARCLLILKPILLADEVTAALDKESAREIRELLHSLPCTMVEIAHKYN
                     AQSYDCIYHLKDKELVRCS"
     gene            13716..14567
                     /locus_tag="TV191_000754"
     CDS             13716..14567
                     /locus_tag="TV191_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1507288.1"
                     /translation="MNIREKFKAIRKQRRLSLKTLGKIAGSATSISDFENGKTNLSND
                     VLLQLLGFMIVEINELFEWEDFHEKELVEAIKQIELAIKSKHIPALSQLQQDFQSLSK
                     TKEQYIYHIISLILTITIAEYQNKEIDPHIMSELTDYFFFLEYWTNLDVGLLGNIVHY
                     MTTDALILLTNDILEHTPQVLRNNLDRIRIDTVLNCLTVLINRKEEKASRTLLKLLFN
                     KHYPNYFAFEKLYLHELQAVYDFNWKDKEQALAAHHVILATISLLFTADEAKEWDSFF
                     QESTSSL"
     gene            14828..15496
                     /locus_tag="TV191_000755"
     CDS             14828..15496
                     /locus_tag="TV191_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEL1507289.1"
                     /translation="MSHKSIHQQLRNAFSFRTAVRVYNDQKIAKEDLDLILDAAWLSP
                     SSIGLEAWRFVVLENEAVKHELKEVSWGAVYQFETASHMILLISEKNARYDGASIKQS
                     LLRRGITDEQALASRLACYEAFQKHDMKIADDPRALFDWTAKQTYIALANMMTTAAFM
                     GIDSCPIEGFNYDKVNAILAKHGIINPDTEGISSMLSLGYRLRDPKHSQTRKPREEVI
                     SFFN"
     gene            15611..16537
                     /locus_tag="TV191_000756"
     CDS             15611..16537
                     /locus_tag="TV191_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL1507290.1"
                     /translation="MTLLSVIIPCFNEEDTIIPYLEEMKQIEAAMTSQLAFEYLFIDD
                     GSTDQTLSVLRELAGRFSNVHYLSFSRHFGKEAGLLAGLEEAKGSYITVMDVDLQDPP
                     ELLPLMYSKLQEGFDVVATRRQSRQGEPAIRSFFARLFYRLVKHVSNTEIVDGVRDYR
                     LMTRQVVDSILELGEVNRFSKGIFSWVGYNTAYISFDNRKRQYGKTSWNFLELLNYSI
                     DGFINFSEMPLTIATWTGTLSFLLSLLAICFIVIRKLLFGDPVSGWASTVSIMLFIGG
                     IQLFCMGIIGKYISKIFLETKKRPVYIIKEKK"
     gene            complement(16521..16709)
                     /locus_tag="TV191_000757"
     CDS             complement(16521..16709)
                     /locus_tag="TV191_000757"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507291.1"
                     /translation="MTLSRLFRCEADARSHTKKDLMVLIGTIKSFCRACHDEGNQSLS
                     ASLAADRGLDDCSVISFL"
     gene            complement(16821..17288)
                     /gene="smpB"
                     /locus_tag="TV191_000758"
     CDS             complement(16821..17288)
                     /gene="smpB"
                     /locus_tag="TV191_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEL1507292.1"
                     /translation="MAKGEGNVLAQHKKARHDYHIVETVEAGIVLTGTEIKSVRAARI
                     QLKDGFAQIKNGEAWLVNVHIAPFEQGNIWNADPERTRKLLLKKREIQHLADELKGTG
                     MTLIPLKVYLKDGFAKVLIGLAKGKHDYDKRESIKRREQDRDIRRVMKSVNRR"
     gene            complement(17291..19615)
                     /gene="rnr"
                     /locus_tag="TV191_000759"
     CDS             complement(17291..19615)
                     /gene="rnr"
                     /locus_tag="TV191_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEL1507293.1"
                     /translation="MMIENITNYLKEHGQSNIHDLAAALEMTDARSFPRLIKAISKME
                     GKGLLSFSDEGEVFLRAPQQKKPEIRVQGIFRANKAGFGFLSVDDNEDDIFIGRDDVG
                     YASDGDRVEAVIKKPANRLKATAAEARVVAIVERSLKTVVGRVILDDDHPKYAGYIKS
                     KNQRIQQRIYIAKSPIALDGTEIIKADIVQYPKAGQDYFVGTVCDIIGHQHDVGIDVL
                     EVLESMDIVSAFPDDVLAEANAIPDAPSDQDLMGRVDLRKETTITIDGADAKDLDDAI
                     HIKRLANGNVELGVHIADVSYYVTEGSALDREAAARGTSVYVTDRVVPMLPERLSNGI
                     CSLNPKVDRLTQSAIMEIDHQGHVVDYQLCQSVINTTFRMTYSAVNQMIAGDSEALRE
                     FDRIADDVSTMVELHQILEAMRVKRGALNFDTQEARIIVNDKGMPVDVVLRQRGVAER
                     MIESFMLAANECVAEHFSRAGLPFIYRVHEEPKAEKLQTFIDYASAFGIQIQGTANKI
                     SQEALQAFMAKVEGSPGAEVLNMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRR
                     YPDLLVHRMIREYNQITQEKVDHFAQVIPELAVSSSQLERRAIDAERVVEAMKKAEYM
                     ADYIGDVFDGVIASVVKFGMFVELPNTIEGLVHITNLPEYYHYNERTLSLKGERSGKV
                     FRAGQPIRVRLVRADKETGDIDFDYLASDYDVVEKTTRSAKAKHKHRQKAASRASRSK
                     ESKPSKPKSKQKTRKKAKKPFYQKAAKKKGRKRS"
     gene            complement(19702..19938)
                     /gene="secG"
                     /locus_tag="TV191_000760"
     CDS             complement(19702..19938)
                     /gene="secG"
                     /locus_tag="TV191_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEL1507294.1"
                     /translation="MYDLLLTILLVLSVLLVIAIFMQPQKNPSSNVFDSSGSEALFER
                     TKARGFEAFMQRFTAVLVFFWLGIALVLAILSSK"
     gene            complement(19984..20130)
                     /gene="rpmG"
                     /locus_tag="TV191_000761"
     CDS             complement(19984..20130)
                     /gene="rpmG"
                     /locus_tag="TV191_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEL1507295.1"
                     /translation="MRVKIHLECSHCGSKNYLTSKNKTSHPEKIKVPKYCPKERKVTL
                     HVES"
     gene            20618..22450
                     /locus_tag="TV191_000762"
     CDS             20618..22450
                     /locus_tag="TV191_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1507296.1"
                     /translation="MRKTMKKMLAASTLCIIMSGSFISGSARVLAEKYYGFNDGTGEH
                     SPFPVYVTPITKPNRNTAKVVYCFNKDMKWPETWDKAAPKKPDNLPLYYDMEGTDQLF
                     STYASGQLTPNVSKVLANIMAKGYPNNNEFAHHFKLTPNSAVKVTQIAVWTVTDNLKN
                     YSQYSLTREEEAALNYLTDKNGDDFSDSIKLKLYIPQNPRTIKYQNLLGYDLIVKTPE
                     KKDNCKCTKIYIEDNGKDGYYLYIYYDNNENNRYDSDKDSLLQKKYIKNGKDGKPGRP
                     GVPGLPGPAGPQGPRGDKGETGERGPKGEKGLDGKPGEKGPKGDTGKDGKDGQPGPQG
                     PKGDPGRDGKDGEPGKPGERGEKGPQGERGPQGLPGPKGEPGIPGPKDEDGKDGAPGH
                     DGQPGPKGEKGDPGQQGIPGPKGEPGRDGKDGEKGERGEQGPQGERGEQGPQGERGEQ
                     GPQGERGEQGPQGERGEQGPQGERGEQGPQGERGEQGPQGERGEQGPQGERGEQGPRG
                     ENPTPTPDPMPQPEPQPEPQPMPDPAPKPESKPEPKPIPQPEVKPQPETKPQQPNKPS
                     TITSQSSGKSLPKTNDTGSLITAFGTGLLTLLGLGFLAKRKRKQ"
     gene            22763..>23237
                     /locus_tag="TV191_000763"
     CDS             22763..>23237
                     /locus_tag="TV191_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1507297.1"
                     /translation="MRKTMKKMLAASTVCIIMSGSFIGGSARILAEQYYGWNDGTRVK
                     SPFFLYVTPTNETTRKTGKNGTIVYCFNRDKEWPANWEEGRSLELVNAETAYKLPIYN
                     KLLGTTDSFTKNASKPRVSGDIGKALIAVLKNGYPNKNLSGLDDTKSRILTQLAIW"
BASE COUNT         7076 a         5364 c         4325 g         6472 t
ORIGIN      
        1 aattggtttt ccattatcat ccaagctact ccaagagtta ctatacaaaa tagttatggc
       61 ctcatctggt ttatctttta aatcatattt ttcgatgatt aaacctaagg cagcagctac
      121 tttaggggct gcaatagagg tcccgtagcc ataagtatat ttcccttcta gtgttgggat
      181 aataacccaa tcttgctcaa ataatttatt gttaatccaa gtgtcatagc catgaagcgc
      241 tagcttcttg cttcctccac ctgccgcaaa gatatcaacg acattccttc cacgattgga
      301 aaagttagat attgcaccat caccatcaac agatcctact gtcacaacat tatctagctg
      361 tgcgggaata tcctctattg tcccatcgac tgaactaaac gctcttcctg tgagagcact
      421 gactaagttc ttaagctcag cttgattatt taagttagct ccctcatcac caacagaagc
      481 aactaccact gagccttgtt tgtgtgcata attgattgcc cgttgatagc tattgattag
      541 agcagttcta tcttcatcaa tatttgatga agcctttaat aaatactgac caagactcaa
      601 atttatgaca tcaacatcat cctttgctgc ttgaataatt gcttttaaaa tccattcatc
      661 ttgagcgttt ccctcttcaa acaccttata cattctaacc ttcatgcctg gagcaattcc
      721 tgtataataa ccatttgaag acatttgtcc aacaacagat gtaccatgac ctgttttatc
      781 caaaacatta ttaacatcaa ttgccttagt tactggatcc tccgtaaaat tttgaacaga
      841 aatgatcttt gaagaaatgt cagtattatt atcagtaata ccagaatcta ttacaccaat
      901 ggttacctca cctgatgact tatgccaaaa cctactacta gtactaatac ttctttgcat
      961 atcccattgt ttattccagt aatttaaatc actatctaaa taaaatgcat gcccaaactg
     1021 atatgtcatt ttgggattta ctgtaaaagt attattcctt gaaatgtcat caatatagtt
     1081 acaattcttt tccaaaatca tagatgagtc atttgcagca gcgattgtca aaacattaat
     1141 ttcaggaatt tcatcaagca ctatcattcc ctgatcattt aattgctttt ttaccttatt
     1201 ggtatctaag ctttctttta taagaatatt atattgagtt ttgctactag tctcagcata
     1261 gacatgtaac atatgaaatt gagatacaaa aatagacagt agcaaacaga aaatcaacat
     1321 tttatgcttc atggtcagca ctcctttaag tattgttttt acacttatcg tatgactaac
     1381 atttcagatt tgtttcagat tctagaaaat aatacttact attgtgctta tttaagtcca
     1441 aaaattagca ttacactcat taagtatctg agattaatct agctaacatt ctaaattgtt
     1501 ttctcccact aatcttttgt tcttaattcc gacttataat taaagacaaa agctaatttt
     1561 tctaactgcc tcgcatagca ctcatacttg ccaatcattg ttgtcatcgt ctcctgattg
     1621 agcttagttt cttcttccac ctgctccagt ttactagctg atatgcaagt gcaatggtcg
     1681 ttttttgtga atcacaccta ctttgaatct ggtaaaatca ttctactaac aaacttcctg
     1741 tgtaatttct agtagcctag gtagcctgat aaagagattt cttcaaataa aaataaccat
     1801 gtcgaatgcc agcgctccat ttcttaccag cattttcatt attccccagc taaagctcta
     1861 tccatgaggc taagtgacct gtgcttagaa ttaactcata tccacactag tctcagaaat
     1921 aaagactgaa gctatcatga tgtcactact aggaatgaat gaaatctagg gtttctactt
     1981 gacagtcata gtgagacaaa caagcggcaa tttgctcttc taaactcccg atttgtttct
     2041 aatagcaagc ataaatctcc atagactacc cccatagaaa atggtggtga ttggagaaat
     2101 caccattaag tgcttcacga cgttgaggag ctttcttctt caaactagta taaacaatta
     2161 atggactact tactctagct gtcataggcg tttgagcaat cagtagttga aatagcttgc
     2221 aaccgaaagc acccagcata ctctcaatgc ggatcggaag ttcaatgcca cctaactgta
     2281 gaattttata atgcaaattg tcctttatta agaaccttat tgatcatttt aagctttagt
     2341 tcgggagagg aacgaatctt tttccttagc agctttacaa tcaattaatc gtgctaaata
     2401 ctttaaatgg aattgattga tatcaaattg tttgaatgaa taactctggt tttgtaggcc
     2461 gcagatttct accttgtctt gatgtcttaa tgtcatgtta aaagcacccc attcgttaga
     2521 tagtttgtct aacttttggg gcgcagttca ttcattagat tttttatcta atttttgaga
     2581 agcagtttac ttctgatgag ggcttctata ttgctttcat tagttctatg agtgagagca
     2641 aagctcttgt agctatttgt cccagatttt tttatgtcat ctgttttgca agtcaagctg
     2701 acgtctgctt aatcagccta tctaaaacca gcttgcttgg tctgcttttt agccttcagc
     2761 tgggcgtgat ttgcgggcaa tatcagccaa aatgttatca acaaatgctg aaatagcttc
     2821 ggtatgtgtt gccttactgc catagcggcg cacattaact gacttgtcct gcatctcctt
     2881 atcaccaacg attaattggt aagggatttt actggtttga gaggcacgaa tcttatattg
     2941 cattttctca ttacgatcat ccacatctgc acgaatccca tgatcacgaa ggattttagc
     3001 aacctcccaa gcatagtcaa tatgggcctc attggaaatt gggataactg ttacctgacg
     3061 tggtgccagc catgttggga aagctccctt ataggtttca atcaaaatag cagtaaagcg
     3121 ctccatggtt gaaatcaccc cgcggtggat catcaccgga cggtgttctt ctccatcagc
     3181 accaatatag ctcagattaa aacgctcagg cagtaagaag tccagctgaa tggttgatag
     3241 ggtttcttca tttccaaggg ctgttttgac ctgaatatca agctttggcc cgtaaaaggc
     3301 agcctctcct tctgcttcaa agtaatcagc gcccatttca tcaagcgcag ccttcagcat
     3361 gctttgagca ttttcccaca tctcatcgtt atcgtaatat ttatgtgtat cctttggatc
     3421 acgataggac agacggaagc ggtaatctgt taggttaaaa tcctcataaa cgtcaataat
     3481 cagctgaaga gctcgctgga attcctcctg aatctgctct ggcgtcacaa acaggtgccc
     3541 atcgtttaag gtcatctccc gcacgcgctg aagccctgaa agagcccctg atttttcata
     3601 gcggtgcatc ataccaagct ctgcaatacg aatcggcagc tcgcgatagg aatgcacatg
     3661 gtttttataa acctgaatat ggtgtgggca attcattgga cgaaggacaa attcttcacc
     3721 atctcccata tccattgtcg ggaacatatc ctcctgataa tgctcccagt ggcctgatgt
     3781 tttataaagc tcaactgaag caagcggcgg agtataaaca tgctgatagc ctgatgccag
     3841 ctctttatca gtgatatagc gctcaagcgt gcgacgaatc gtcgctccat ttggtagcca
     3901 aaatggcaag ccttgtccta cctcctgaga gatcataaac aaatcaagct ccttgcctag
     3961 cttacggtga tcgcgctcct tagcctcctc aaggcgtgtc aaataggcct tgaggtcctt
     4021 tttatcaaac caggctgtcc catagacacg ctgcatcatg ttattatcgc tattgccacg
     4081 ccagtaagct ccagctacat ttaacaaatg aaagacccga atccgacctg ttgacggcac
     4141 atgaggacca cgacaaaggt ccacaaattc accctgacgg taaacagtta agccagccgc
     4201 atcatctgca tgctcattaa tcaactcaac cttataaggg tcatccttaa aaagctcaag
     4261 agcctcttct tttgtgatct cctcacgaat acatggaaag ttctctttga caattttttt
     4321 catttcctct tcaatgcgag gcaggtcttc gttagagatt tgaccatcag cattatctgt
     4381 atcataataa aaaccatctg caatggcagg gcctacacca agatgcagct tggggaacaa
     4441 gcgcttagca gcttgagcaa acaagtgagc cgcagaatga cgcagcacct caaaagcgtc
     4501 ctcatgatca gcagttataa tttctatact accgtcctct tcaatggcgc gcgtggtatc
     4561 aattaattga ccattaaact taccagccaa ggccttttta gctagagatt tgctgataga
     4621 gtcagcaatc tcaaaggttg tgacaccaga ttcaaattca cgcaccgcgc cgtctgggaa
     4681 agtgattgta atcatctgtt ttctcctata aaccatctag atacttaaaa caagctaatc
     4741 aagcagggct atatctccca agccttctgc tgctacgaca aaataaaaac tgactgcctc
     4801 ccaaaggacg caatcagcgt ggttccacct ttatttatgc atgacaaaga aatcctgtcc
     4861 tgcacctcag cttggctata tcgtgaccac cgttttatgt ttgcataaaa gcaaggaagg
     4921 agtattacac tagacaccct gtgctcttct caccaaccag cactcgctta aaggatgcga
     4981 cctaatctaa cttgtcttcc tgattattat agcaatattt ggaaataatt caagtgattt
     5041 ttcctaaaaa agctgagata agcccacaga cctccaagcc cacaaggcaa gaatgactag
     5101 gcaaggaacc ctgaaacttc tgccacaagc ctttgaagaa cagctcaaac aggacttgcc
     5161 gcctgtcgtc tcagttcaca agacaacaaa ctaaatcctt tagacaaatg attatcctaa
     5221 agagctatct gctctctcac gcagaaccaa agcctgtaat tgcaggcttc tttgtttatt
     5281 tagccttagt ccaaaaagtc tcggatcgca ttgaccagct tgataggggc tttgagcacc
     5341 ttgacagatg tcagtgcagt tgccttagct gctcgcttag gcaagtgaat cgctccttga
     5401 accagcttga ttgagccact cttttctgtt cgattgagat agagacttag ctttttcgtc
     5461 tctttattgt gtcgcgaaat caaggtatct aaataaaagg tgtacactga tttgccaaaa
     5521 tgctgagctg aaatctcata gcgcttctca tctagcagcc tctggttcat ttgaggtgtt
     5581 tctaaaatgg catcaataat cgcatctgac aattctgact cagcataata aagtgttcca
     5641 aacatcttat cggtaatcaa atcatctagg tagggattgc catgagcgat gatgggcttg
     5701 ccactagcaa ggctctcaat ataagttagc ccctgtgtct cactcgttga cgctgaaata
     5761 aagaaatcac aggccttata ataaagccca acctgatcat gagcaatcat accagtaaag
     5821 accacatgat cctcaacgcc taagctgaca gccagctcct ttaaggcttg aagataagga
     5881 ccatcaccaa caatgacaag cttgatcctg ctattttcac tcaaaacagc tggcagctga
     5941 tggataatag cctgaatatt cttctcataa gacacccgcg acaggctcaa tagcatggtc
     6001 tcatcatcag aaatggccaa ttcctttctc aaggcagcga catcttcttt tttaatatcc
     6061 tcacgaacat agttctctag tgcaatgcca gtcggaatca cacgcttagg aatggttacc
     6121 tcgtaccctt ccaaaagatt tagcacaatc cgacttgggc aaataacacc atcaaggtcc
     6181 tttaaatacc cacgaagcag gggcttgacc atgctaggtc gaatgatctt accattagca
     6241 atatagctca cataatcctc atactgggta tgataggtgt gaacaaccgg aattcttaag
     6301 gccttgccca ccattttgcc caacaaacct aagctaaact ctgtttgagt atggataatg
     6361 tctaaatgat attccttagc aatcttgtag gaggaaatga gcccacgata aaccacacga
     6421 cgatccgtaa aggacacaaa aggaacactt ggtaaccgaa taatggtcgg atcctcaaag
     6481 cgcttaacat gcttgtctgt tgttgtgaaa atatagacct catgcccctc tttttccagc
     6541 tcctccttta gggtgcgaat actggtagcc actccggaaa cctgtggaaa ataggtatct
     6601 gtaaatagac ctacacgcat cttataactc cattactttt tgataaatag ccactaattg
     6661 atgagcaatc ctatcaaggc tgcgcccctc ggcgacacga tagccggcct ctgttttgtt
     6721 gctttcccct gaaagaatgc gtcttaaggc tgcaacaaag cctgaggtat catttgccaa
     6781 ctcagcactg tcttgatcaa tccagccctc atagactggt atatcgcgta aaacaagatg
     6841 ctgccggctg gctaaggctt cgagaaccac aatgccttct gtttcctcac gacttgggaa
     6901 gaaaaaggcg tcagccccag tcatagcccc ctcatacaca tctcccttga tataaccagg
     6961 gaagatcaca ttatcggggt gcttaccgtt gacaatctgg cggacacgag caggaataac
     7021 ccatttattg gtatcaccaa accagataaa ccgaacatct ggcatcatct cagcaacctt
     7081 aacaaactca tcaatccctt ttctaagaaa gaaaagcccc gctcccatga ctaccttctc
     7141 accctctttg aggttaaaat aacgccgaaa ggcagcttct ttgtcagcat tagcaccata
     7201 ttgctccaaa tcaatcccat tagatactgc aaaaatagga gtcttaaccc cgtaatgctc
     7261 aatcaaggct ttagaataag gggtcggtgt gataatggcg tccgccttat tgtaaaagcg
     7321 gcagagatag gctttgaata aaggagacac tagatttgaa aaaataaagg aatttctaaa
     7381 atcctcctct gtcgaatgcc catgcatgat caccttttta ccggcctttt gagcctttga
     7441 catcaaaagc cagcttttaa gcccataggt attgagatga accaaatcat agtcgtcctt
     7501 tggatcagtg gtgaactcct gtcccacaag cgatagcgct tttgcctgat gcttaatcgc
     7561 tcgcccgata cctgattttc ttaaataatt ttctgcttct aaatacaata agactttcat
     7621 actgtctatt atagcctatt ttatggtatt tttcactaag agagttaaaa atcagccctt
     7681 agactgattt tagggtaagg cttcttctac ccctatactc atctcaaaaa tgcttttaag
     7741 tcctgctttt gctgtcatca aatggctgat cttggtaata tcagctagac caagatcgtg
     7801 aaagctccag ctcaaggctc acgtattagc cctttcaaga aagcctccca cctttctcac
     7861 tggccaaaaa gccagcaaga cctggccttt tcttctgatt aattcagcct atcagctaag
     7921 cttcttcttt tggctgtgct ttttgtaaca cccaggctga gatagagcct gcctctacct
     7981 tgaaatctgc ccagccatcc tcagcaacaa caacagtctc ctgacaattg tctaagaaat
     8041 cacaaaaaac ttgaccagca taggcttgac caacctccat gtgcttccag cctgcatcgc
     8101 cattagacaa aacaactgcc aaaggctgag gacgctgatc atctcctaag caggtccagc
     8161 cgatacaatt ggcatgatca aagtaatcaa tctgctcccc atagaccagc tgctgcctga
     8221 gctctgccat ttttgtgata acctccttaa aactttgctg agggtagtct ccagaaatac
     8281 cataataatc accataaaaa agacagggct tgccctcttg tcgtaaaaga atcagcccat
     8341 aggctaaggg cttgaaccat tcctcaacag ttgactctaa ggcttgccct ctttgggtgt
     8401 catggttttc cacaaaggta atagcaaggt ctggccgact agccacaaga ctgccatcaa
     8461 aaatagtggt caaatcaaaa tcagctccct gctggctagc attaaaaaag gacatgtgca
     8521 gcgcaacatc aactagagca aactgagcct tcgttgcttc gaggtaatcc tccatagatt
     8581 cctgatcaga cttccagtat tctccaaaaa cctctaaatc gggctttagc tgggtacgaa
     8641 tatcattgat aaaggtctga ataaaataag aatcaatatg cttcacagcg tctaaacgaa
     8701 agccctcaat accagttgtc tcaataaacc acttggccca atcctgtaaa ttttggatta
     8761 cctcaggatg cttgaaatct aagtcattgt acattagata atcaaaatta ccatgctcat
     8821 cgtcaatcag ctcatcattg gcccagccct tgttatcacc ggtgatcatg taaatacctg
     8881 tttcattagc cttggcgtca taatccaatc ccgtaaaatg gtaccagtgc catttaaagt
     8941 cattataggt attttgtctg ccgggaaaat caaagcctgt ccagccttca atctcatagg
     9001 gctctgtaag ggcctgctga cggttctctg gattcatttt gatcacagaa aagcgttcct
     9061 tgtgatcacc attagccttg tggttcagca caacatcagc aataggcttt atttttgcct
     9121 cttttagggc tgcaatcagc tgcaaataat cctctttgct gccatatttt gtgctgacag
     9181 ttccattttg gttaaactct cccaaatcaa acaaatcgta aacaccgtac cccacatcat
     9241 cagagctagt gcccttaaag gcaggcggca gccacagctg actaacccct agctgttgta
     9301 gctcaggaat actgcttttc agcctttgcc aatgccttcc atcggcaggc aaataccatt
     9361 caaaggcctg cattaatagt tgatgactca tcttaacctc ctaaaaagga caaaccagaa
     9421 aactcctagt ttgtcctcaa aactgcctaa acaggcagaa ctattttgtt gtcccacgct
     9481 ttttaatgcc atggttcaat aaaatttctt tttcttctaa ttcttcctta ttcatgatct
     9541 tagtgagcat acgcatgcta acagccccca agtcatagac cggctggctg atagagctca
     9601 aatttggacg tgtgtactga acgactggag aatcattgct tgtgataatc tcaaagtctt
     9661 ctggaacacg cttaccagct tcaaaaagac cattcaaaag gcctgctgcc agctcgtcct
     9721 ctgcaacata ggcagctgtc gctccggaat tgatcacacg ctgagccagc tcaaagcctt
     9781 ccttataaga atagttggcc tcaaacacca gaccctcttt aaagtcaagc ttgttcttct
     9841 tgagtccgtc cttgtagcca gctaaacgca cctttccgtt gatatcatca atgagcggcc
     9901 ctgaaacaaa ggcaatgctt tggtggtctt tagctaaaat atccaccaca tcagcaacag
     9961 ccgccttata atcaatgtta acacttggca gctgatgatc cagatcaacc gttcctgcca
    10021 gaacgattgg cgtacgcgaa cgagaaaact ctgcccgaat cttgtcagtc aagtgatgtc
    10081 ccatgaaaat aatgccatcg acctgctttg caaagagggt attcacaaca ttgacctctt
    10141 tatcatcgtc ctcatcactt gaagcaagaa caatattgta cttgtacata gcagcaatat
    10201 catcaattcc ctttgccaga atagaaaaat agctatttgc aatattagga atcacaacac
    10261 cgactgttgt tgtcttttta cttgcaagac cacgagcaac agcatttgga cgataatcga
    10321 gacgatcaat aacctctaag acctttttgc gggtattttc ctttacattt ttgttaccat
    10381 ttacaactcg actaactgtc gccattgaaa ctcccgcttc gcgagcaaca tcataaatcg
    10441 tgattgtatc atctgtattc attcttcatc ttcctttcta actgaaaatg acgctttcaa
    10501 aaagtatttt agcatgattt gtaaccactt tcaagtatta acggttgatt tttgaaaaag
    10561 ttttcaaaaa ttcataataa gcttgctttt ttaagtattt tttggaaaaa tagaaggcag
    10621 aaagaaggtt tatctatgac taaattagat caaattcgtt tgtaccttaa tcaggaaaag
    10681 gctgagcttg ctatcttttc tgattctgta acgatcaatt acttaactgg ttttttatgt
    10741 gatcctcatg aaaggcagat gttcctattt gtctatcatg acaaggctcc tgttttgttt
    10801 gtaccagctt tagaggttgc aagggctgaa caattgctgg acttccctgt ttttggctac
    10861 gttgactctg aaaatccttg ggaaaaaatc aagtctatcc taccaagcac agcagcaaag
    10921 accatttacg ctgagtttga tcatttgaac attaccaagt ttcaagggct gcagagtgtc
    10981 ttttcaggac gctttgacaa tctaacccct tacattcaaa gaatgcggct catcaagtct
    11041 gctgacgaaa ttcaaaaaat gctgattgct ggagaatttg ccgataaggc tgtcaatgtg
    11101 ggctttgata atatttcact tgacgtcacc gagacagata tcatcgctca aatcgaattt
    11161 gaaatgaaaa aacaaggcat cagcaagatg agctttgaaa cgatggtttt aactggtaac
    11221 aacgctgcaa acccacatgg cattccagga accaataaaa tcgaaaacaa tgccctgctg
    11281 ctctttgacc ttggtgttga aacattaggc tatactagcg acatgacgcg tacagttgcc
    11341 gttggaaagc cagaccaatt taagcttgat atttatcagc tttgcttaga ggctcagcta
    11401 actgctcttg atatgattaa gccaggagtg actgcagctc aggtagatgc cgctgctcgc
    11461 caagtgattg aaaaggctgg ctatggcgac tacttcaatc acaggctcgg ccatggtatc
    11521 ggtatggacg ttcacgaatt tccatcaatc atggctggca atgacctgat tcttgaagaa
    11581 ggcatgtgct tctcagttga gcctggtatc tatatcccag gcaaggttgg ggttcgtatt
    11641 gaggactgtg gtcacgtaac taaagacggc tttgagctct tcacccaaac accaaaagaa
    11701 ttactatact ttgaagggta ataggaggct taaaaagcct gaaacaaaat gtctcagacc
    11761 ctaatatcta aagcaacagc acttggtctg ttacttttca tattacaggc tattttctca
    11821 caaggaaaag tcaaagcacc ccttgatggg aaatcagagg ggcaaaagct atttgtacta
    11881 agctcaaaag ctaatcaaga gcacctgacc agctctttat cctttaagtg ataaatgcaa
    11941 tcataagact gtgcattata tttatgagct atctcaacca tggtgcaggg gagtgaatgg
    12001 agtaactcac gaatctctct ggcgctttct ttgtctaggg cagctgtgac ctcatcagcc
    12061 agcaaaatcg gttttagtat cagcaagcag cgtgcaattt ccagcttcat gatttgcccg
    12121 ccagagagat tttgcccatc tagatggaga tcaagatctc cgtttagctc attccaaaga
    12181 tgaacctgct gtaatatctc ctttagtcgc tggtccgaat aatcctgaaa cagcgtgaga
    12241 ttatctcgca agcttccttc aaatatgtaa ggcttttgat gtatcaaaga cacaacatca
    12301 taggaaggaa aatagcgttt tccattggca gcttcaaaat aaatagttcc agaataatcc
    12361 ttatcctcac cacacaaaag agcaaataaa gtagatttcc cactaccact ggctcctgtt
    12421 agcaaggttt tgtgccctgc tgaaatatga ccatctatcc cttgaaaaat aagcctatga
    12481 tcaaaatact tatctaacct cttaaagtag atatcaagtg taagatcatc tgtaggggtt
    12541 aaggcttgat gttttgtctc ttcctccaga gccaatactc taaccatctt ctccttaaca
    12601 gcagttgcag actgtaaact cgaagtagct tctaataatt gctgcaaggg agagacaaga
    12661 ttcgtagaag ctgttatcat agcaatgaga gttgttagtg atagacttga atagctcatc
    12721 accaacagac caataataag aggactaacc aagccaatcc cttttaatgg accagtccaa
    12781 aacattacca gattgtgggt agtataatag ctatattgct tgtcttccat atgctgaatc
    12841 atttctaaca catggtgagc aaaagcttcg ttggcttgat tactctgtat cgtgtctgcc
    12901 cccttagtaa aatcggtgat actggctagg cttttctccc tcgcctgact aagctctaag
    12961 cctcgtgatt gaagtaagtg attgaacaca aactgtggaa taatcatcaa aaagccacca
    13021 atagtaaagg caataccaat ataaatatcc tgcaaaagaa ggtacaagac agaggctaag
    13081 atagataggc caaaaacagg ataaatgaat aaggggacca aatactcctg ccaaaacata
    13141 ggaatatctt gggtcaaaaa cgaatttaag gctgaagtaa aatagttgag ctgtttatga
    13201 taaaaatgat ataaagcctt ctttgcaata aggcaattaa acgctctaac catagaacgt
    13261 gctaaaatgt tattaagata catgcacata taaataaaga caaaaaaagc tacgcctcca
    13321 agaccaaaaa gcaataccat tcctttattg ttcatatcaa tttgccctgc tatctgaatt
    13381 aatactgata acaatagtcc ctgcaaggaa tagagcaaag ccaataaact atacaagcaa
    13441 agctgccatt ttgaaatgac ttgtaaaata cttttcatat caatcactcc tcacctgaaa
    13501 cctaaatgta tcgctctctt ggaaagtata aacgaaacat cctcatacac caatcatttc
    13561 caccacaaac tagattcttg aatgttaaat caagctcttg atcaaaatca tgttctctga
    13621 tttcttgaac aaccattggt tctctccttt cattcttact atttctagta tataatggga
    13681 aaaaatacga aaggaaaaat ttcggaaatc cggatatgaa tatcagagag aaatttaaag
    13741 caattcgtaa acaaagaaga ctatccttaa aaacgcttgg taaaatagct ggctcagcca
    13801 ctagtatttc tgacttcgaa aatggaaaaa cgaacctttc taatgatgtt ttattgcagc
    13861 ttttaggctt tatgattgtt gaaataaacg agctattcga atgggaggat tttcacgaaa
    13921 aggaattggt tgaagccatc aagcaaatcg aactggcaat aaaatctaaa catattcctg
    13981 ctctatctca gctacagcag gactttcaaa gcttatctaa gacaaaggaa cagtacattt
    14041 accacatcat ctcactgatc ctaaccatca ccattgcaga atatcaaaac aaagagatcg
    14101 atccacacat catgtctgag ctaacagact acttcttttt cttggagtat tggactaacc
    14161 ttgatgtcgg cctactagga aacatcgtcc actacatgac aacagatgcc ctaatcttat
    14221 tgacaaatga catcttagag catacgcctc aagtactccg aaataaccta gatcgtatta
    14281 ggatcgatac tgtattaaac tgtcttactg tcttgattaa tcgtaaagag gagaaggcaa
    14341 gcagaacact tcttaaatta ttatttaaca aacattatcc taattacttt gcctttgaaa
    14401 agctctattt acatgaatta caagcagtct atgattttaa ctggaaagat aaagaacagg
    14461 cgcttgcagc tcatcacgtc atactggcta ccatttcatt actatttaca gctgatgaag
    14521 ccaaagaatg ggacagcttc tttcaagaaa gtactagctc tttgtaatac tccagctcat
    14581 acactaaaga aaagcaagga taatcacata aaaactaatc acatcacttt gccctgctag
    14641 ctgaattagc ttgggtcatc tcttatgccc agcaaaacat catctagtct cagctttctt
    14701 ccaaagcttc ttgtctctct gggcttgcaa gcttttgata gcttaagagg cacaagcatt
    14761 aacaaaggct aacaaatgcc tgtaaaaata tgctatgata ggggtaacaa aaacctagga
    14821 ggtgcttatg tcacacaaat ccattcatca acagcttaga aatgcttttt cctttcggac
    14881 agcggtacgc gtctacaatg accaaaaaat agccaaagaa gacttagacc tgattttaga
    14941 tgctgcctgg ctcagtcctt cctctatcgg ccttgaggcc tggcggtttg tcgttttaga
    15001 aaacgaagct gtcaagcatg agctaaagga ggtctcttgg ggagcagttt atcagtttga
    15061 gacagctagt catatgatcc ttttaatcag cgaaaaaaac gccagatatg atggcgcttc
    15121 tatcaagcaa agcttattgc gcagaggcat tactgacgag caagccttgg ccagtcgtct
    15181 ggcatgctac gaagccttcc aaaagcatga tatgaaaata gcagatgatc ctcgggctct
    15241 ctttgactgg actgccaagc aaacctatat cgcgcttgct aatatgatga ccactgctgc
    15301 ttttatgggg attgactctt gtccgattga gggctttaac tatgacaagg taaatgctat
    15361 cttagcaaaa catgggatta tcaaccctga taccgagggt atctctagca tgctgtcttt
    15421 aggctatcgc ctgcgcgatc ccaaacactc acaaaccaga aagcccagag aagaggttat
    15481 ttccttcttt aactaagccc cttttgccat tgctcccaaa gaaagtgcaa agacagtcct
    15541 ttgccttttc tttttcataa ctgtcgaatt atggtacaat gtgtcaaaag acctatggaa
    15601 agtgatgcct atgacattat tatctgtaat tatcccctgc ttcaacgaag aagacacgat
    15661 tattccttat cttgaagaaa tgaagcaaat cgaagcggcc atgaccagcc aattagcctt
    15721 tgaatatctt tttattgatg atggctctac agatcaaacc ctgagcgtgc taagagagct
    15781 tgcggggcgc ttctctaatg tgcattacct ctccttttca cgacattttg gcaaggaagc
    15841 tggactatta gccggcctag aagaggcaaa aggaagctat attacggtga tggacgttga
    15901 cctccaggac ccacccgagc ttctcccgct gatgtatagc aaattacagg agggctttga
    15961 tgtggttgcc acaagaagac agagccgaca aggagagcct gctatccgtt ccttttttgc
    16021 tagactcttc tacagattag tcaagcatgt ctccaacacc gaaatcgtcg atggggtacg
    16081 tgattatcgt ttaatgacaa gacaggtggt ggatagtatt ttagagttgg gagaggtcaa
    16141 tcgcttttcc aaggggattt tttcttgggt tggctacaat actgcctata tcagctttga
    16201 caatcgtaag cggcagtacg gcaaaaccag ctggaacttt cttgagcttt tgaactactc
    16261 gatagacggc tttatcaatt tttctgagat gcccttaacc attgctacct ggactgggac
    16321 acttagcttt ttgctatctc tgctagccat ttgctttatt gttatacgca agctgctttt
    16381 tggtgatccg gtttcaggct gggcaagcac tgtatccatt atgctattta tcggtggaat
    16441 tcagctgttt tgcatgggaa tcattggaaa atacatttcc aagatcttcc ttgaaaccaa
    16501 gaaaagaccc gtctacatca tcaaagaaaa gaaataacag agcaatcatc aaggccccta
    16561 tcagccgcca atgaggccga taaggactgg ttgccctcat catgacaagc acgacaaaaa
    16621 gacttgatgg tcccaatcaa aaccatcaag tcttttttag tatgtgacct tgcgtctgcc
    16681 tcgcacctaa aaagacgaga taatgtcata accaccgtct atctactgac cccaaaaagt
    16741 tggacaattt agttttaagc aagggattta gttctgtatt gcacaggact aagcaaggcc
    16801 atcagcttgt aaacagacgc ttagcggcgg ttcacactct tcatcacacg ccgaatgtca
    16861 cgatcctgct cgcgtcgctt gatcgattca cgcttgtcat aatcatgctt tcctttggca
    16921 aggccgatta acaccttggc aaagccatcc ttaagataaa cctttagagg aataagggtc
    16981 attcctgtgc cctttagctc atctgctagg tgctgaatct cacgcttttt gagcaataat
    17041 ttgcgcgtgc gctccggatc agcattccag atatttccct gctcaaaggg agcaatatga
    17101 acattgacca accaggcctc accattcttg atttgggcaa agccgtcctt gagctggata
    17161 cgcgcggcac gaacactctt aatctccgta ccggtcaaca caattccagc ctcaactgtc
    17221 tcaacgatat gatagtcatg acgagccttt ttgtgttgcg ctaatacatt accttcacct
    17281 tttgccatgc ttaactcctt ttacgacctt tctttttagc agctttttgg taaaatggtt
    17341 tctttgcttt ttttcttgtc ttctgctttg attttggctt tgagggcttg gactccttac
    17401 tcctgctagc ccttgaagca gccttttgcc tgtgcttatg cttagcttta gctgaccttg
    17461 tggtcttttc aaccacatca tagtcactag ccaagtaatc aaaatcaatg tcacctgttt
    17521 ccttgtcagc cctcaccaat ctaacccgaa tcggctgacc tgctctaaat acctttcctg
    17581 agcgttcacc ctttaaggag agtgtccgtt cattatagtg ataatattca ggcaaattgg
    17641 taatatgcac cagaccttca attgtatttg gcaattcgac aaacatgcca aacttaacca
    17701 cactagcaat cacgccatca aacacatcac caatataatc tgccatgtat tctgcttttt
    17761 tcatcgcctc aaccacacgc tccgcgtcaa ttgcacgacg ctctagctga gatgacgata
    17821 ctgccaattc tggaataacc tgtgcaaaat gatccacctt ctcctgcgtg atctgattgt
    17881 attctcgaat catgcggtgc accagtaaat cagggtaacg acgaatcggg ctggtaaaat
    17941 gcgtgtagta gtctgctgct aagccatagt gaccatgatt atgctcagaa tacctagcct
    18001 gctgcataga gcgcagcagc atcatattca aaacctctgc tccaggactt ccttctacct
    18061 ttgccataaa ggcctgcaag gcttcttgag aaatcttatt agcagttccc tgaatctgaa
    18121 tcccaaaggc actagcgtaa tcaataaagg tctgcaattt ctctgccttt ggctcctcat
    18181 gaacccggta aataaatggc aagccagccc ttgaaaaatg ctcagcaaca cattcatttg
    18241 ccgctagcat aaaggactca atcatgcgct ctgcaacacc tcgctggcgc aagaccacat
    18301 caaccggcat gcccttatca ttgacaataa tcctagcctc ctgcgtgtca aagttcaagg
    18361 ccccgcgctt cacacgcatc gcctctaaga tctgatgcag ctcaaccata gtactcacat
    18421 catcagcaat tctatcaaat tccctaagcg cctcactgtc acctgcaatc atctgattga
    18481 ccgcgctgta ggtcattcta aaggttgtgt taatcactga ctgacacagc tgataatcaa
    18541 ccacatgtcc ctgatgatca atctccatga tcgctgactg ggtcaaccgg tcaacctttg
    18601 gattgagaga gcagatacca tttgacaacc gctccggcag cattggcacc acacgatctg
    18661 tcacgtaaac agaggtcccg cgcgcagctg cctcacgatc caaggctgac ccttccgtca
    18721 catagtagga cacatctgcg atatgaaccc caagctcaac gtttccattg gccaatctct
    18781 tgatatggat ggcgtcatct aggtctttag catcagcacc atcaatagtg atggtcgttt
    18841 ctttgcgcaa atcaacacgc cccataagat cctgatcact cggagcatct ggaatggcat
    18901 tggcctcagc tagaacgtca tctggaaacg ccgatacaat atccatagat tccaaaacct
    18961 ccagcacatc aatgccgaca tcatgctgat gcccaataat atcacacaca gtccctacaa
    19021 aataatcctg cccagcctta gggtattgca caatatcagc cttaatgatt tcagtaccat
    19081 ctaaggcaat tggagatttt gcgatataaa tcctctgttg aatcctttga tttttcgact
    19141 tgatgtagcc agcatactta gggtgatcat catctaaaat aaccctacca acaaccgtct
    19201 ttaaagagcg ctccacgata gctaccacgc gagcctctgc tgctgtagcc ttaagccgat
    19261 tagctggttt tttaataaca gcctcaaccc tatcgccatc actagcatac cccacatcat
    19321 cacgaccaat aaaaatgtcg tcctcattgt catcaaccga caaaaagcca aagccagcct
    19381 tattggcacg aaaaatacct tgaaccctta tctctggctt tttttgctgt ggtgctctaa
    19441 gaaacacctc accctcatct gaaaaagaca aaagtccctt gccttccatt ttggaaatgg
    19501 ctttaatcag gcgaggaaag ctcctcgcat cagtcatctc tagtgcagcc gccaaatcat
    19561 gaatatttga ttggccatgc tcctttaaat aattcgtaat gttctctatc atcataccta
    19621 tcttctattt ctaacaccat acttgatggt tgtgctcatt gataaaaaaa tgagctagac
    19681 taactctgtc aagctcactc cttatttact tgataaaatg gcaagcacta acgcaattcc
    19741 taaccaaaaa aacactagaa ctgctgtaaa acgttgcata aaagcttcaa atccgcgagc
    19801 ttttgtacgc tcaaacaagg cttctgagcc actgctatca aaaacattgc tactaggatt
    19861 tttttgtggc tgcataaaga tagcaatcac aagcaacact gataatacta gcaatatcgt
    19921 aagtagtaag tcgtacatgt taattcctcc actgtagtct caatcattct aacacaaaac
    19981 caactaagat tcaacatgca gcgttacttt tctctcctta ggacagtatt taggaacctt
    20041 aatcttctca gggtgacttg ttttattttt actagtcaaa taatttttgc tgccgcaatg
    20101 gctgcactcc aaatgaatct ttactctcac atcatttccc taatcttact atattttatc
    20161 agcgtcataa ggcttcaaat cacccgcagc ttctttatta aagatatctc tagttattat
    20221 agcatattat ccagtaagaa aacaaactca ggacttttag caaaaaaggc ttaagcgcca
    20281 accaataaac attccaaggc tatcggggaa tattttctaa tggttattat aaatcatgaa
    20341 caattaccta acaaagcaac tccaaaacaa agataaaaga cgaacattca ccttgctgct
    20401 cagctatcaa gataaacaat cctgatagca tcaattttct ttaggtcctc agcaatcggt
    20461 tgtaatatca gacaattcag gtgttgatta aaaaaaacga aactacggag accaattgtc
    20521 agaaagctat tcacagcccg caggcgtcgt gctaaagtat tgtctggaaa aagaaaggtt
    20581 taggaatgat tatacctaaa ctcaaaggag agaaacaatg agaaaaacaa tgaagaagat
    20641 gctagcagcc tcgacgctct gcatcatcat gtcaggcagc ttcatcagcg gctcagctag
    20701 agtgttggcg gagaagtatt atggttttaa tgatggcaca ggagagcatt caccattccc
    20761 tgtatacgtt actccaatta ctaaacctaa taggaatact gccaaagttg tctactgttt
    20821 caataaagat atgaagtggc cagaaacttg ggataaagca gcaccaaaaa aaccagataa
    20881 tttacctcta tactacgata tggaaggtac tgatcaatta ttcagtacat atgcaagtgg
    20941 acaacttact cctaatgtca gtaaagtctt agctaatata atggctaaag gttatccaaa
    21001 caacaatgag tttgctcacc attttaaact cactcccaat tccgctgtaa aagttactca
    21061 aatcgcagtt tggactgtta cggataacct aaaaaactat tctcaataca gtctaaccag
    21121 agaagaggaa gctgcattaa attacctaac tgacaaaaat ggggacgact ttagcgatag
    21181 tatcaagtta aaattataca ttccacaaaa tcctcgaact ataaaatatc aaaatcttct
    21241 aggttatgac ctaatagtta aaactccaga aaaaaaagat aattgtaaat gcaccaaaat
    21301 ttatatagaa gataatggaa aagatggcta ttatctgtat atttattatg acaacaatga
    21361 aaataataga tatgactcgg acaaagatag cctattgcaa aagaaataca taaaaaatgg
    21421 gaaagatggg aaaccaggaa gaccaggggt tccaggactt cctggccctg ctggacctca
    21481 agggcctaga ggagacaaag gagaaaccgg ggaacgtgga cctaaaggtg aaaaaggtct
    21541 agacggtaag cctggtgaaa agggtcctaa aggcgataca ggaaaagatg gtaaggacgg
    21601 acaacccgga cctcagggac ctaagggtga ccctggacgt gatggaaaag atggcgaacc
    21661 tggaaaacct ggcgagcgcg gtgagaaagg acctcaaggc gaacgtggac ctcaaggact
    21721 tcctgggccc aaaggtgagc ctggaattcc agggcctaag gatgaagatg gaaaagatgg
    21781 tgctcctgga catgacggac aaccggggcc taaaggtgaa aaaggggacc ctgggcaaca
    21841 aggcattcca ggacctaaag gggaacctgg acgtgatggt aaagatggag aaaaaggcga
    21901 gcgtggagag caaggacctc aaggcgaacg tggagagcaa ggacctcaag gcgaacgtgg
    21961 agagcaagga cctcaaggcg aacgcgggga gcaaggacct caaggcgaac gtggggagca
    22021 aggacctcaa ggcgaacgcg gagagcaagg acctcaaggc gaacgcggag agcaaggacc
    22081 tcaaggcgaa cgtggagagc aaggacctca aggcgaacgt ggggagcaag gacctcgtgg
    22141 agaaaatcct actcctaccc cagatccaat gccacaacca gaaccacaac cagaaccaca
    22201 accaatgcct gatccagcac ctaaaccaga atccaagcca gaacctaagc cgatacctca
    22261 accagaggtt aagcctcagc cagagacaaa acctcaacaa ccaaacaagc catcaaccat
    22321 tactagccaa tctagcggca aatcactgcc aaaaacaaat gacactggca gcttgatcac
    22381 agcatttggt acaggcttac tcactcttct tggactaggc ttcctagcaa aacgcaaaag
    22441 aaagcaataa ttaaaacact acccatagcc ttttaatcat tggctatcaa ctagataaca
    22501 aaaagcttat cgttttactc ctaacgatag gctttttcgc attccctatt gcttggtctc
    22561 aatactattt ttccagcttt aggctggttt tgctaatcca aaataatatc agacaatttc
    22621 cgttttaatt aaaaaaaaaa aaaacgaaac tacggacgcc aattgtcaga aaatggttca
    22681 cagcttagag tcaccatgtt aagctattct acgaagaaga aaggtttagg aatgactatt
    22741 tctaaactca aaggagagaa acatgagaaa aacaatgaag aagatgctgg cagcctcgac
    22801 agtctgcatc atcatgtcag gtagctttat cggcggatca gccagaatcc tagccgagca
    22861 gtattatggg tggaatgatg gaacaagagt aaaatcacct tttttccttt atgttacgcc
    22921 aacaaatgaa acgactagga aaaccggaaa aaatggtaca atagtctatt gtttcaacag
    22981 agataaggaa tggccagcaa attgggaaga aggaagatcc ttagaactag tgaatgctga
    23041 aacagcttat aaattaccca tctataataa attactaggt acaactgatt cctttactaa
    23101 aaatgctagt aaaccaagag tatctggaga tattggtaaa gcgctaatag ctgtactgaa
    23161 aaatggttat cctaataaaa atttatccgg attagatgac actaaaagtc gaatactaac
    23221 tcaactagct atctggt
//
LOCUS       DARYXW010000024        22449 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.024, whole genome shotgun sequence.
ACCESSION   DARYXW010000024 DARYXW010000000
VERSION     DARYXW010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22449)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22449)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22449
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.024"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            26..1594
                     /locus_tag="TV191_000764"
     CDS             26..1594
                     /locus_tag="TV191_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEL1507298.1"
                     /translation="MKKLVLSCLATLLIFLGGIGTVQADHYLRVGMEAAYSPFNWTQD
                     DSSNGAVPIEGTSQYANGYDVQIAKKIAKALNKDLLVVKTSWTGLIPALTSGKIDLIA
                     AGMSPTAERKKEIAFSNSYYTSEPVIVVASNGKYAKARSIKDFSGAKVTAQQGVWHVN
                     LLPQLEGAKLQTPMGDFSQMRQALTSGVIDGYISERPEAMTAETANKAFKMITLTKGF
                     TVSESDAAIAIGMKKGDDRLTAVNQVLDAISQKERLALMDKMIQQQPSEPKADEAKPS
                     FIKQTWSIFQSNWKQFLRGTGMTLLISMIGTITGLFIGLLIGIYRTAPKAKGKLAALA
                     QRLFGGLLNVYIEVFRGTPMIVQSMVIYYGTAQAFGISIDRTLAAIVIVSINTGAYMS
                     EIVRGGIFAVDKGQFEAATALGFTHGQTMRQIVLPQVVRNILPATGNEFVINIKDTSV
                     LNVISVVELYFSGNTVATQTYQYFQTFTIIAIIYFVLTFTVTRILRYIERRFDADTYT
                     TGANQMQVSEVPNV"
     gene            1587..2327
                     /locus_tag="TV191_000765"
     CDS             1587..2327
                     /locus_tag="TV191_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1507299.1"
                     /translation="MSNPIIEIKNLKKSYGNNEVLKDISLTVNKGEVISIIGSSGSGK
                     STLLRSINLLEEPSAGEILFHGDNVLAEGYNLTHYREKLGMVFQSFNLFENLNVLENA
                     IVAQTTVLKRERSEAEKIAKENLKAVGMTEQYWQAKPKQLSGGQKQRVAIARALSVNP
                     EAMLFDEPTSALDPEMVAEVLKTMQDLAKSGLTMIIVTHEMEFARDVSDRVIFMDKGL
                     IAEEGTPKQLFEQPKQDRTKAFLQRFLS"
     gene            2675..2791
                     /locus_tag="TV191_000766"
     CDS             2675..2791
                     /locus_tag="TV191_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HEL1507300.1"
                     /translation="MAEKTDLASAYRRLKSPNIKTKKRALKIIHEHKRYGKK"
     gene            complement(3315..4205)
                     /locus_tag="TV191_000767"
     CDS             complement(3315..4205)
                     /locus_tag="TV191_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEL1507301.1"
                     /translation="MLEAILIIGFLVIVILSIMASTLYVVRQQSVAIIERFGKYQGTA
                     TSGIHIRLPFGIDRIAARVQLRLLQSEIIVETKTKDNVFVTLNVATQYRVNEQNVIDA
                     YYKLIKPEAQIRSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMSTYGYIIV
                     KTLITKVEPDAEVKQSMNEINAAQRKRVAAQELANADKIKIVTAAEAEAEKDRLHGVG
                     IAQQRKAIVDGLADSIQELKEANISLNEEQIMSILLTNQYLDTLNTFAAKGNQTLFLP
                     NTLNGVDDIRTQVLSALKTR"
     gene            complement(4468..6132)
                     /locus_tag="TV191_000768"
     CDS             complement(4468..6132)
                     /locus_tag="TV191_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEL1507302.1"
                     /translation="MSNITTSLFQEMVQAAATRLGKQAEYVNSLNVFPVPDGDTGTNM
                     SMTMDNGAKEVADKPASTVGEVGQILSKGLLMGARGNSGVITSQLFRGFGQSIKSKEE
                     LTGKDLAQAFQMGVEVAYKAVMKPVEGTILTVSRGAATAALKKADLTDNAIEVMQAAL
                     DGAKGALAKTPDLLPVLKEVGVVDSGGQGLVFIYEGFLSALNGDYVASEDFKATPANM
                     SEMIKAEHHKSVAGHVATEDITYGYCTEIMVALKQGPTYVKEFNYDEFQGYLSGLGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLIKIKVDNMRNQHEAQVQKIDNEPTKA
                     EAKEFGLIAVVAGDGLAEIFKAQGVDYVISGGQTMNPSTEDIVKAIEAVNAKQVIILP
                     NNKNIFMAAQSAAEVVDIPAAVVETRTIPQGFTSLLAFDPSKTLEDNVADMTASLSDV
                     VSGSVTLAVRDTTIDGLDIHENDFLGMVDGSIVVSNPDMEATLKTTFDHMIDEDSEIV
                     TIFIGEDGSSEVAQGLADYLEETYEDIEVELHQGDQPVYPYLMSVE"
     gene            complement(6132..6497)
                     /locus_tag="TV191_000769"
     CDS             complement(6132..6497)
                     /locus_tag="TV191_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL1507303.1"
                     /translation="MTVKINTKDGLIELSDDVIATVVGGSATEIFGVVGMASKSALKD
                     NFQSLLRKENYAKGVVVKSTDMGISVDVYTVMSYGVKISEVSKNIQERVKFNLESQLG
                     LSADMVNVYVQNIKVVGEN"
     gene            complement(6649..6837)
                     /locus_tag="TV191_000770"
     CDS             complement(6649..6837)
                     /locus_tag="TV191_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEL1507304.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRTVKPNLQKVTILVDGKP
                     KKVWASARALKSGKVERI"
     gene            complement(7297..7662)
                     /locus_tag="TV191_000771"
     CDS             complement(7297..7662)
                     /locus_tag="TV191_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507305.1"
                     /translation="MADLSISKKSLLKGLGLLSVCLGLAVGTSRTAFAHVSTFYWNRS
                     WYLSQQNKGTDEEVEQKKKELIKKIKDSDLDGFIMGNYIDTINSHVFLYKLLHLEEYI
                     DFLIAQFDHFTPEQLEKRD"
     gene            complement(8252..9133)
                     /locus_tag="TV191_000772"
     CDS             complement(8252..9133)
                     /locus_tag="TV191_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEL1507306.1"
                     /translation="MPIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKQAP
                     VLIQTSMGAAKYMGGYKLAKVLIETLVESMNITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLEKAREIVKLAHAKGVSVEAEVGTIGGEEDGIIGSGELAPIEDAK
                     AMVATGIDFLAAGIGNIHGPYPENWTGLDLDHLKKLTDAVPGFPIVLHGGSGIPDDQI
                     QAAIKLGVAKVNVNTECQIAFANATRAFARDYEANVAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSANKA"
     gene            complement(9336..9421)
                     /locus_tag="TV191_000773"
     tRNA            complement(9336..9421)
                     /locus_tag="TV191_000773"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9385..9387),aa:Leu,seq:aag)
     gene            complement(9476..10402)
                     /locus_tag="TV191_000774"
     CDS             complement(9476..10402)
                     /locus_tag="TV191_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEL1507307.1"
                     /translation="MKTIRLSKYFGILLLLLTLASVGASFYFFHVAQVREEKSFINNK
                     KRTPDNPLYPAELAFDSLTREKRSITNRGRQQVAWYLPASQDTHKTAIVVHGFTNDKE
                     DMKPYAMLFHSLGYNVLIPDNEAHGESEGDLIGYGWNDRLNLLAWIDLLVSEDKGSRI
                     SLFGLSMGAATVMMASGEQLPSQVVNIVEDCGYTSVWDELKFQAKAMYNLPAFPLLYE
                     VSALSKIRAGFSYGEASSVKQLAKNKLPVLFIHGDKDTFVPTEMVYQNYQATKGPKEL
                     MVVKGAKHAKSFETNPDQYKEKIAAFLQKYEK"
     gene            complement(10762..12375)
                     /locus_tag="TV191_000775"
     CDS             complement(10762..12375)
                     /locus_tag="TV191_000775"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEL1507308.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NIDPGTMSPYQHGEVYVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITDALKEKIKRAATTTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGSENVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPVE
                     QGIKNKLAQFCDVNPEAVIESRDVEHLYQIPLNLQAQSMDQIVCDHLKLDVPQADMTE
                     WSAMVDRVMNLKKTTRIALVGKYVELPDAYLSVVEALKHSGYANDTAIELDWINANDL
                     TAENAKKLLGQADGIIVPGGFGQRGTEGKIQAIRYAREHDVPMLGICLGMQLTCVEFA
                     RHVLGMEKANSFELDPDTAYPIIDIMRDQIDIEDMGGTLRLGLYPCKLKAGSRAAAAY
                     NNQEVVQRRHRHRYEFNNKFRQDFEAAGFVFSGVSPDNRLVEIVELPEKKFFVAAQYH
                     PELQSRPNRPEELYTAFVTAAVKNKNQSL"
     gene            complement(12649..13215)
                     /locus_tag="TV191_000776"
     CDS             complement(12649..13215)
                     /locus_tag="TV191_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEL1507309.1"
                     /translation="MKLDVFAGQEISELSMIEVARAILEERGRDNDMYFSDLVNEIQN
                     YLGKSDADIRYALPFFYTDLNTDGSFIPLGENKWGLRSWYAIDEIDEEIITLEDEEDG
                     APKRKKKRVNAFMDGDEDAIDYSADDPEDEDFVRESSDIEYDEEDPDDEKSEVESYDS
                     ELNEIIPEDDFEEVDLNEEDEEDEEEEE"
     gene            complement(13482..14765)
                     /locus_tag="TV191_000777"
     CDS             complement(13482..14765)
                     /locus_tag="TV191_000777"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEL1507310.1"
                     /translation="MSTSFENKATNRGVITFTISQDKIKPALDQAFNKIKKDLNAPGF
                     RKGHMPRPVFDQRFGEEVLYEEALNIVLPAAYEGAVAELELDVVAQPKIDVVSMEKCQ
                     EWTLTAEVVTKPEVKLGDYKDLTVEVEASKEVTDEEVDAKVERERNNLAELVVKEEAA
                     VEGDTVVIDFVGSVDGVEFDGGKGDNFSLELGSGQFIPGFEEQLVGAKAGDTVEVNVT
                     FPENYQAEDLAGKAAKFVATVHEVKAKEVPELDDELAKDIDEEVETLDELKAKYRKEL
                     EASKEAAYDDALEGAAIELAVENAEIVELPEEMVHDEVHRSVNEFMASMQRQGISPDM
                     YFQLTGTSQEDLHKQHEAEADKRVKTNLVIEAIAKAEGFEASDDEIEKEINDLAAEYS
                     MPVEQVRSLLSADMLKHDIVMKKAVEVITSSAKAK"
     gene            complement(15114..16523)
                     /locus_tag="TV191_000778"
     CDS             complement(15114..16523)
                     /locus_tag="TV191_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEL1507311.1"
                     /translation="MVTHKTKRFLKALSVTSLTLGLVLSGLAPLAPANLASAQEVQSD
                     NQPVAMKDGAILHAWCWSFNTIKENMSAIKEAGYTSIQTSPINAVIEGAGGSKDLKNW
                     YYHYQPTDYTIGNYQLGTEEEFKAMAQEADKYGINIIVDAVLNHTTSEIKAVSPKITA
                     IDNWTHGNDKIVNFNDRYQITQKSLLGLYDFNTQNRAVQEYMLNYLKRAVADGADGFR
                     YDAAKHIELPGEHNSDFWKVILNNGAKFQYGEILQGDACNEAGYGNIMGVTASNYGKL
                     IRKVLGQGYVKDWDLVNFQVHGVSEDKLVTWVESHDTYANDDEESTKLTDEDIKLGWG
                     IIAARNEGAPLFFSRPRGGGGQNGRFPGESQIGDAGSDLFKDPTIVAINQFRNRMNGQ
                     SEYIRNPGMDQGLVMIERGQKGAVITNLTIVDKDFSSTTTLADGDYKDAVTGTVYHVS
                     NHNITGHLAKKSVAVLLPA"
     gene            16974..17813
                     /locus_tag="TV191_000779"
     CDS             16974..17813
                     /locus_tag="TV191_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HEL1507312.1"
                     /translation="MTFILTYFNQLHLENIMVLVFSKLVSITLLLIFFVIFKKITTAL
                     FEKAIAKSFSYSRQTEARKKTLSKLLHNTLNYVFYFLLIYWILSLLGIPVSSLLAGAG
                     IAGVAIGLGAQGFLSDVVNGFFILFENQFEVGDTVTIAGIEGTISSVGIRTTQVRGFD
                     GTLHFIPNRNITVVSNKSRGNMRALIDIPLYSSTDLEHVTQIIKAVNKREVPNFPQIV
                     GQPNILGPQTNPNGQFTFRVSIFTENGQQFTIYYSFYKLYQEALLREGIKLPTASAIS
                     PLA"
     gene            complement(17909..18469)
                     /locus_tag="TV191_000780"
     CDS             complement(17909..18469)
                     /locus_tag="TV191_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019777568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEL1507313.1"
                     /translation="MNLKVLREEARSILLDIVERSAIKKGQLFVLGLSSSEVLGGRIG
                     QHSSLEVGEVIVKLILEELSFRGIHLAVQGCEHINRALVLEESVAEEYRLEIVNVLPS
                     LHAGGSGQLAAFKYMKQPVEVEAIAAHAGLDIGDTSIGMHVKRVQVPLVPIQRELGGA
                     HVTALASRPKLIGGVRARYQPDPIRK"
     gene            complement(18482..18955)
                     /locus_tag="TV191_000781"
     CDS             complement(18482..18955)
                     /locus_tag="TV191_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL1507314.1"
                     /translation="MKQTRELALVSILTALTVVLGRFVSIATPTGFLSLLDAGVYVTA
                     FSLGKKEGMLVGGLSAFLLDLISGYPNWMLISLVAHGAQGYLAGLPGRHRFLGVGLAS
                     VIMVGLYFLAAIPMYGMGAAISEISGNAAQNTLGIGVGYLLYLGVKKQLVKVSDD"
     gene            complement(18961..19710)
                     /locus_tag="TV191_000782"
     CDS             complement(18961..19710)
                     /locus_tag="TV191_000782"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEL1507315.1"
                     /translation="MKNKVLTIAGSDIFSGGGLQADLAVLHQLDSFAFLAITCLTSCD
                     AKGFSIHPVATDLLAKQLSSLAAIPFQAIKVGLLPRPEIAEQVALFLELKKDIPVVLD
                     PVLVFKENQDQTVVEMTQALRSLFPLTAVITPNLREAERLAGLAINSREQMVEAAKKL
                     YEMGAKRVVIKGGNRFDQRVALDLFYDAKTLCFLEKPVLAKQNSGAGCSFAAAIAAYL
                     AKGYSPLRAVEQAKDLVFEAIQQSNDYGVVL"
     gene            complement(19700..20449)
                     /gene="truA"
                     /locus_tag="TV191_000783"
     CDS             complement(19700..20449)
                     /gene="truA"
                     /locus_tag="TV191_000783"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEL1507316.1"
                     /translation="MTRYKAIISYDGTLFSGFQRQSQARTVQEEIEKTLQKLTGGQGI
                     QIHGAGRTDAGVHAYGQVIHFDLEQKRDPEKLRFALDTQTPDDIDVISLEIAADDFHA
                     RYHKHFKTYEFLVDIGRPKNPMMRHYATHYPYPLDIAKMQAAIKDLVGTHDFTGFTAA
                     GTSVKNKVRTITAATLTQDPKTGFLVFTFSGNGFLYKQVRNMVGTLLKIGNGRLPIEQ
                     IRLVLESKNRQLAGPTAAGNGLYLKEIIYEE"
     gene            20636..22000
                     /locus_tag="TV191_000784"
     CDS             20636..22000
                     /locus_tag="TV191_000784"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEL1507317.1"
                     /translation="MKVTKFGGSSLASAQQLEKVLAIIKDDPERKIIVVSAPGKRSPT
                     DTKVTDALIAYYKAYVSDRHYHKHLEWIINRYQQICNDLTLDSKIITQIKASLEQLAR
                     LPKEHNPYLYDTFLAAGEDNNAKLVAAYLKANGLTASYLHPKDAGLIVSSEPQHARLL
                     PISYDKLEALKDHDDILVIPGFFGVTNENQICTFSRGGSDITGSIIAAGVTADSYENF
                     TDVNGIFAAHPGVVKQPQTITELTYREMRELAYAGFSVLHDEALIPAYRGKIPIVIKN
                     TNNPSHPGTTIVLEHQRKSNPVVGISGDDHFVSINLSKYLMNREIGFGRKLLQILEDL
                     NIRWEHMPTGIDDLSIVLRERELTPIKEEEILRRLVQQLEVDEVSITRNLSIIMIVGE
                     NMKSHIGVTSAATKALSEHHINIAMISQGSSEVSVMFVINSTDEKKAIRALYQTFFSP
                     DRPL"
BASE COUNT         6635 a         5313 c         4072 g         6429 t
ORIGIN      
        1 cacgttttta aaaaaggaga cctatatgaa aaagctagtc cttagctgct tggccacctt
       61 acttattttt cttggaggaa taggtactgt gcaagcagat cactatttac gagttggtat
      121 ggaggcggct tactctccat ttaactggac tcaagatgat tcgtcaaatg gcgctgttcc
      181 tatcgaagga accagccaat acgccaatgg ctatgatgtg caaatcgcta aaaaaattgc
      241 aaaagcatta aacaaagact tattggttgt gaaaacctcg tggacaggtc ttattccggc
      301 tctgacctca ggtaagattg atttaattgc agctggtatg agcccaacag cagagcgcaa
      361 aaaagaaatt gccttttcta acagctacta caccagcgag ccagtcattg ttgtcgcctc
      421 aaatggtaag tatgccaagg ctcgttctat caaagatttt tcaggtgcta aggtaactgc
      481 tcaacagggc gtgtggcatg tcaacctgct accacagcta gagggggcaa agcttcaaac
      541 accaatggga gatttttctc aaatgcgcca ggctctaacc tctggagtga ttgatggcta
      601 tatctccgag cgccctgagg caatgacagc cgagactgcc aacaaagcct ttaaaatgat
      661 cactctaaca aaaggattta ccgtttcaga gtcagacgct gccattgcca ttggcatgaa
      721 aaaaggagac gaccgcctta cagcagtcaa tcaagtgctt gatgccattt ctcaaaagga
      781 acgccttgcc ttgatggaca agatgatcca acagcagcca agcgagccca aagctgatga
      841 agcaaagccc tcctttatca agcaaacctg gtcaatcttt caaagcaact ggaagcagtt
      901 ccttcgcggg acaggcatga ccctcctgat ttcgatgatt ggtactatca caggactttt
      961 catcggtctc ttgattggta tttaccgtac agcaccaaag gctaaaggca aattggcagc
     1021 gctagctcaa aggctctttg gtggactact caacgtctat atcgaagtct ttcgtgggac
     1081 gccaatgatt gttcaatcaa tggtgatcta ctacggcact gcacaggcct ttggcatttc
     1141 cattgaccgc acactagcag ctatcgttat tgtctcaatc aacacaggtg cttacatgag
     1201 tgaaattgtc cgaggcggta tctttgcagt tgacaaaggg cagtttgaag cagcaacagc
     1261 ccttggcttt actcatgggc aaaccatgcg tcagattgtc cttcctcagg tggttcgtaa
     1321 tatcctacct gctactggta atgagtttgt catcaatatc aaggatacct ctgtcttgaa
     1381 tgtcatttca gtggttgagc tatatttctc aggaaataca gtggctactc agacttatca
     1441 atacttccaa acctttacca ttatcgctat tatttacttc gtcctaacct ttacggtaac
     1501 gcgtatcctt cgctatatcg aacgtcgctt cgatgctgat acttacacta ccggagcaaa
     1561 ccaaatgcaa gtttcggagg tcccaaatgt ctaatcccat tattgaaatt aaaaacctaa
     1621 aaaaatctta cggcaacaat gaggtcctaa aggacatctc gctaaccgtc aataaaggag
     1681 aggtgatttc aatcatcggt tcatctggat caggcaaatc aaccctccta cgctcaatca
     1741 acctattaga agagcctagc gccggagaaa ttctctttca tggtgacaat gtgcttgcag
     1801 aaggctacaa cctgacccat taccgtgaaa aattgggcat ggttttccag tccttcaatc
     1861 tctttgaaaa tcttaacgtt ttagaaaatg caatcgtagc tcaaacaact gtcctcaaga
     1921 gagaacgatc agaggctgaa aaaatcgcca aggaaaatct caaggcagtt ggcatgaccg
     1981 agcaatactg gcaagccaag cctaagcagc tatcaggcgg acaaaagcaa cgtgttgcta
     2041 tcgcccgcgc cctatctgtt aaccctgaag ccatgctgtt tgatgagcca acatcagctc
     2101 ttgacccaga aatggtcgca gaggtcttaa aaaccatgca agatctggct aaatcaggct
     2161 tgaccatgat tattgtcact cacgaaatgg agtttgcaag agatgtttct gaccgtgtca
     2221 ttttcatgga taaggggctc attgcagaag aaggcacgcc aaagcagctc tttgagcagc
     2281 caaagcagga ccgaaccaaa gcatttttac agcgcttttt gtcataagcc taaaagccag
     2341 tctaaccata ggtgttagat tggctttttt tgataagtca catctgctaa gcagcataat
     2401 gatcatatag actactttag atcaaagaaa agacctatta taggacaatt tccctcaaca
     2461 ggcacagata ataaacctcc ttttgaaggt tgtgctgcta ctttttcaaa gctgctaagg
     2521 caactggtct acaaaaatca tttctcaaat gagacggtaa ctgttaagct tgatctctat
     2581 tctaaaattt caacacaaaa tactttactg gttaataact ttgtgctata ctgtctttat
     2641 taacgttaat aatatatttt agtaggagga tagcatggcc gaaaaaactg acctcgcgtc
     2701 agcttacaga agactaaaaa gcccaaatat taaaactaaa aaacgtgctc tgaagattat
     2761 tcacgagcac aaacgttacg gtaaaaaata gtattctatt tttatctctc caaatttaag
     2821 tcagataaaa aatgattagg acaccatccc tccgtcttaa tcattttttg atggccaaga
     2881 aaagaaagct ttaagcattg ttaaccatca acaagctgag gacacacaca tctgatagag
     2941 ctgccaatag tagcagttag gaaatgctac actcagcttt taggtccatg cttcagcatt
     3001 ttcaagcaac cggataccaa gaaaactaac cttttagcac agcacaaagc ggcacttgaa
     3061 ctcactttgt tccctcattt gctctcttag cggctaagct tcaaaggtga ttgaaacaac
     3121 ccattgcaat tggtctagct tccaagctgt ttgagcctgt gattcttgct agcatttcag
     3181 acatagcaac atttttcaat agccattatg cttaagacaa tagtgaaata aagacgactg
     3241 ccttactttt caagaacatt gacgagccat catacaaaaa gcaagctgat gctgaccagc
     3301 ttgcttaata tatattatct tgtttttaag gctgatagca cctgagtgcg aatatcatca
     3361 acaccattta gagtatttgg taggaaaagg gtctgattac cctttgcagc aaaggtattg
     3421 agggtatcta agtactggtt ggtcagaaga attgacatga tctgctcttc attcagtgaa
     3481 atattagcct ccttcaattc ctgaatagaa tcagccaagc catcaacaat agccttacgc
     3541 tgctgtgcaa taccaacacc atgcaggcga tccttttcgg cttccgcttc tgctgcagtt
     3601 acaattttaa tcttatcagc attagccaat tcctgtgctg ccacacgctt acgctgagca
     3661 gcattaattt cattcataga ctgcttgact tcagcgtctg gctcaacctt tgtaatcaag
     3721 gtctttacaa taatatagcc ataggttgac atttcttctg ctacctgatg ctgcacctcc
     3781 aaggcaattt catctttttt ctcaaacaat tcatctaagg ttagctttgg aacagaagag
     3841 cgcaaggcat cttcaatata agacctaatt tgagcctctg gcttgatcaa tttgtaataa
     3901 gcatctatca cattttgctc attcacacga tattgagtcg caacatttag cgtcacaaaa
     3961 acattgtcct tggtctttgt ttcaacaata atctctgact gcagcaaacg caattgcaca
     4021 cgcgcagcaa tgcggtcaat cccaaagggc aatcgaatat gaataccact agtagctgta
     4081 ccttgatatt taccaaagcg ctctataata gcaacagatt gctggcgcac cacatacagc
     4141 gtgcttgcca taatggataa tatcacaatc accagaaatc caataatcaa aatagcttct
     4201 aacatgttaa tctcctcctt ataaagccct agctggatag ctatacggct ttttatgatt
     4261 gcctcattgt tataagacaa ttataaaaca tttttgtctt ttgtcaataa aaatctcaac
     4321 gtctatcagc cggctttaca gctgctagag accactaaaa gtctacacct gacgacaggc
     4381 tgcaatcatt gcttcttaat agtcaagtct tccttccaaa gacaaaagga gctaagcctt
     4441 gcctaactcc tctctttgtt ctattcatta ttcaacactc ataaggtatg gatacacagg
     4501 ctgatctccc tgatgcaact caacctctat atcctcatat gtttcctcga ggtaatcagc
     4561 aagaccttga gccacttcac tgctgccatc ctcaccaatg aagatcgtaa cgatttcgct
     4621 gtcctcatca atcatgtgat caaaggtagt ctttagggta gcttccatgt ctggatttga
     4681 cactacaatg ctgccatcga ccattcctaa aaagtcattt tcatgaatat caaggccatc
     4741 aatcgttgta tcgcgcacag ccagagtcac acttccacta accacatcag acaggcttgc
     4801 tgtcatatca gctacattat cctccaaagt ttttgaagga tcaaaggcca gcaggctcgt
     4861 aaagccttgt ggaattgtac gtgtctccac aacagccgca ggaatatcca caacctcggc
     4921 tgctgattgg gctgccatga agatgttttt attgtttggt aagataatca cctgcttagc
     4981 attgacagct tcgatagcct taacaatatc ctcagtagat ggattcatgg tttgtccacc
     5041 tgagataacg tagtcaaccc cctgtgcctt aaaaatctct gccaggccat cacctgcaac
     5101 aacagcaatc aggccaaact cttttgcctc tgccttagta ggctcattgt ctattttttg
     5161 tacctgtgcc tcatgctgat tgcgcatgtt atctacttta attttgatca gtgagccgta
     5221 cttcagaccc tcttgcatca ctagccctgg atcctctgta tggacgtgaa ccttaacgat
     5281 ctcatcatca tttactacta aaagcgaatc accaagccca ctcaaatagc cctgaaattc
     5341 atcataatta aattctttaa cataggtagg accctgcttt agagcaacca taatctcagt
     5401 acaatagcca taggtaatat cctcggtagc aacatgacct gcaactgatt tgtggtgctc
     5461 agccttaatc atctcagaca tattggcagg agtggcctta aagtcctcag aagctacata
     5521 atcaccattt aaggcagaca agaagccctc gtaaataaag acaagacctt gacctcctga
     5581 gtcaacaaca ccaacctctt ttaaaactgg cagcaggtct ggtgtttttg caagggctcc
     5641 ttttgcacca tctagcgctg cttgcatcac ctcaatggca ttatcagtaa ggtctgcctt
     5701 tttcaaggct gctgttgctg caccacgaga aacggtcaaa atagtcccct caacaggctt
     5761 catcaccgcc ttgtaggcaa cctcaactcc catctgaaag gcctgagcta aatccttacc
     5821 tgtcagctcc tcttttgact tgatactttg gccaaagcca cgaaaaagct gcgaggtaat
     5881 aacaccagaa ttgccacgcg cccccatcaa gagacccttg gataggatct gcccaacctc
     5941 accaaccgtt gaagccggct tatcagcaac ctctttagca ccattatcca ttgtcatgct
     6001 catattagtc cctgtatcac catctggtac aggaaaaacg tttaaggaat tgacatattc
     6061 tgcttgttta ccaagacgag ttgctgccgc ttggaccatt tcttggaata agcttgttgt
     6121 aatatttgac actaattttc tcctacaact ttaatatttt gcacgtaaac attcaccata
     6181 tccgcagaaa gcccaagctg actctcaagg ttaaatttca cacgctcctg aatatttttg
     6241 gatacctcac taattttaac accgtagctc ataacagtat agacatcaac tgaaataccc
     6301 atgtccgttg acttaacaac tacaccctta gcataatttt ctttgcgaag tagcgattga
     6361 aagttatctt ttagagcact tttactagcc ataccaacaa cgccaaaaat ttccgttgct
     6421 gaacctccaa cgacagttgc aataacgtca tcagatagct caattagacc atcttttgta
     6481 ttaattttta cagtcatagt tactacctca aaaagttttt atcagcttat tttatcataa
     6541 ttcaaggtca atgtaaaaag atataagcga agaaaggtca cctctatcat gcttttctaa
     6601 gctttttctg aaaacgacta agaaaaaaag ccctaaggct tatttcgatt agatgcgttc
     6661 tactttacca gatttaagcg cacgagctga agcccaaact ttttttggtt taccatcaac
     6721 aaggatagta actttttgaa gatttggttt aacagtacgt tttgtttggt tcatagcgtg
     6781 tgaacggttg ttaccagata cagtcttacg acctgtgaaa taacatactt tagccattgt
     6841 aatctatttc ctcctaggta gaatatgttt acggatgtgc tagcaccaca tacttaccta
     6901 gtctatcaca actcttacct tttggcaagc tattttttac atctgcaggc cttagccact
     6961 aagcagcaaa atgtccctct taatagctaa gcactcactt gctcctctcc tataaatagg
     7021 tctataagaa tcaataatac cctatctatc acaaatgtct aagggctgct gtcagctcga
     7081 aagccttctc ttagaacgct aaaactactc taagaaatag aggttattta acaggctttg
     7141 ctgtagttgc ctagctgaaa tcctataagc atgcactaaa aaagactaaa caagacatca
     7201 cacaaccaca ttagtaggga gattagcctg aggagtgctt cttgtttagt cttttatcct
     7261 cttgaaagcc ttgatcagta tcgtgattgc tgatttctaa tcacgcttct ctaactgctc
     7321 aggtgtgaag tggtcaaact gggcaattaa aaaatcaata tactcttcaa ggtgtaaaag
     7381 cttatagaga aaaacgtggc tattaatggt atcaatataa ttacccataa taaagccatc
     7441 taaatcagaa tctttaatct tcttgattaa ttccttcttt ttttgttcaa cctcttcatc
     7501 agtgccttta ttttgctgag acaggtacca ggacctattc caataaaagg ttgatacatg
     7561 cgcaaaagct gtccggctag taccgactgc taaaccaaga caaacagata gtagtccaag
     7621 gccctttaaa agagactttt ttgaaatact tagatctgcc atagcgagtc ctccttttta
     7681 tttttctaac caaaccatac taaaatataa ctatattgta aaataaaaag tattgtatta
     7741 gaaataagta aaaataaagc tatgaatagt tgacctaact aaacccaaca aataagatgc
     7801 tacatgacaa aattcctttt attctcacca cctgtgatct catcaaaagc tctctaaacc
     7861 agagaggcat agacagctac cgaatgaagc cttagtaata gctgtctcag ctcaccttaa
     7921 actaataggg tcgataaata aggagacatt tgcgcagcag aagctgatag tgtcaaaggt
     7981 tctacttcag caagcatatc atgagtcacc tatttcagca caggcttggt aatgtttgga
     8041 tagtacaaag cgtttttctc aagaacgttc aagatccttc cagtcatagc agagcagccc
     8101 ttaccacaga catctgctag cacacacctc aaaaacaaag acataatcgc tcaagtaggg
     8161 ctattcttta tcggcaaggg gattaggcga aggaactata aaaaggccta tccttgcgga
     8221 taaaccctga tttaatcacg tttagcagtc attaagcctt gtttgctgag ccaaagacat
     8281 caatacgttc ttcaacagaa gcctggatcg ccttaacacc atctgccaag aatttacgtg
     8341 ggtcaaagag ttttttctta tcgtattctg caacgtttgc ttcgtaatca cgcgcaaagg
     8401 cacgagtagc gttagcaaat gcaatttgac actctgtatt aacattaacc tttgcaacac
     8461 caagcttgat agctgcttga atttggtcat caggaatacc tgaaccacca tgaagcacga
     8521 ttgggaagcc tggtacagca tcagtcaatt tcttcaagtg atctagatca agaccagtcc
     8581 agttttctgg gtatgggcca tggatattac caatacctgc agccaagaag tcaattcctg
     8641 tagcaaccat tgccttagcg tcttcaatcg gagcaagctc accactaccg atgataccgt
     8701 cttcttcacc accaattgta cctacctcag cttcaactga aacaccctta gcatgtgcta
     8761 gcttaacaat ttcacgtgct ttctcaaggt tttcttcaac tggaaggtgt gaaccgtcaa
     8821 acatgattga agtgtaacca acctcgatac attcaagagc atcttcatag tgaccatgat
     8881 caagatggat cgcaaccggt acagtgatgt tcattgattc tacaagagtt tcgataagaa
     8941 ccttagctag cttgtagcca cccatgtatt tagctgcacc cattgaggtt tggataagaa
     9001 caggagcttg tttagcttct gctgcacgca ggatcgcttg agtccattca aggttgtttg
     9061 tgttaaatcc accaacagca tagccgttat cacgtgctgc ttggacaaat ttttctgctg
     9121 aaacgattgg cattttaata agcctcctct tatattttgg gttaacccca tttacattgt
     9181 tcattttagc acaattttca agaaatttcc agcccctcat cagcttaaag cgttttctcg
     9241 attcatctta tcacaggctc acaattgagc atttggctag cagcagtctt ttcaggaaat
     9301 aaaaaaaaag atgaatccaa gattcacctc tgcgatgcgg agagtgggac ttgaacccac
     9361 acgacctaaa gcggtcacag gatccttagt cctgcgcgtc tgccaattcc gccatccccg
     9421 cttgctcttt agcaacatat aaaattatat cagctgggag ctttactgtc aatacttatt
     9481 tctcatattt ttgcaaaaag gccgcaatct tttccttgta ctggtcggga ttggtctcaa
     9541 aggacttggc atgcttagcc cccttaacaa ccattagctc tttaggacct tttgttgcct
     9601 gatagttttg atagaccatc tctgtcggga caaaggtatc cttgtcgcca tgaataaaga
     9661 ggactggcag cttatttttg gccaattgct tcaccgagct agcctcacca tagctaaagc
     9721 cggcacgaat tttagagagg gctgaaacct catacagcaa gggaaaggct ggtagattgt
     9781 acatggcctt agcttggaat ttcaattcgt cccaaacact agtatagcca caatcctcaa
     9841 caatattgac aacctgacta ggtagctgct caccgcttgc catcataacg gttgcggcac
     9901 ccatggataa gccaaataag ctaatgcgac tgcctttatc ctcgctaacg agcaaatcaa
     9961 tccaggcaag taggttcaag cgatcattcc agccatagcc aatcaagtca ccctcactct
    10021 caccatgagc ctcattatct ggtatcagca cattgtagcc taggctgtga aaaagcatgg
    10081 catagggctt catgtcctct ttatcatttg taaagccatg aacgacaata gctgtcttat
    10141 gagtatcctg cgaggcaggc aaataccatg caacctgttg acgtcctctg ttagtgatac
    10201 tgcgtttttc acgcgtcaag ctgtcaaaag ctagctctgc tgggtacaaa ggattgtctg
    10261 gggttcgttt tttattgttg ataaatgact tttcctcacg cacctgagca acatggaaga
    10321 aataaaagct agctcccaca ctagccaggg tcaacaagag cagtaaaatg ccaaaatact
    10381 ttgataatcg aatggttttc ataccgacta ttctacaaga aaatatggaa aaaagaaagc
    10441 tttatgctaa aaataaccga taccttttta ctgccttctt aaggccaaat ctcaagccag
    10501 ccagtagcta aagcgttttc gcaggaattg aagctcaata gtttaaagaa tatacaagct
    10561 accttcaaaa tagctttgac cagatcaaga ggaagtccgc tgacagcatt tgataagagg
    10621 taaaatggtg ctttttgcta tattaaaagt ggctgatgtc atcatctcat cagccactca
    10681 aagacttaat aagcctatca aagctgctaa ctctcagcac ctaaataagg ctcaaggata
    10741 gcctcttacg tcatactaga cttaaaggct ttggttttta tttttcactg ctgctgtaac
    10801 aaaggcagtg tatagctctt caggacgatt aggacggctt tgcagctctg gatggtattg
    10861 ggctgccaca aagaatttct tctctggtaa ttctacaatc tctaccaaac gattgtccgg
    10921 cgaaacacct gagaaaacaa agcctgctgc ttcaaagtcc tgacggaatt tattgttaaa
    10981 ttcgtaacgg tggcggtgac ggcgctgcac cacctcttgg ttattgtagg ctgctgcagc
    11041 tcttgagcca gcttttagct tacatgggta tagccccaga cgtaatgttc ctcccatgtc
    11101 ctcaatatca atttgatcac gcataatatc aatgattgga taggcagtat ctggatccag
    11161 ctcaaacgaa ttggcctttt ccatgcctag gacatgacga gcaaactcaa cacaggttaa
    11221 ttgcatgcct aagcaaatgc ccagcatcgg cacatcatgc tcacgcgcat agcgaatggc
    11281 ttgaattttt ccttctgttc cacgctgacc aaagccgcca ggaacgataa tgccatcagc
    11341 ctgcccaagc agcttcttag cgttttcagc tgtcaggtca ttagcattaa tccaatcaag
    11401 ctcaatagca gtgtcattag catagccaga atgctttagg gcttccacaa cagacaaata
    11461 cgcatctgga agctcaacat atttcccaac caaagcaatc cttgtcgttt tcttgaggtt
    11521 catcactcta tcaaccatag ctgaccattc tgtcatatct gcctgaggca cgtctagctt
    11581 caagtgatca cagacgattt gatccattga ttgagcctgc aaattcagtg gaatttgata
    11641 caaatgctcc acgtcacgag attcaataac ggcttctggg ttaacatcac aaaattgcgc
    11701 cagcttattt tttatcccct gctcaacagg ctcctcagta cgaatgacaa gcatattcgg
    11761 ctgaatgcct aagccgcgta attccttaac agagtgctgt gtcggctttg ttttcatctc
    11821 gcctgctgct tttaaataag gcagtagggt tgtgtgaata tacatcacat tttcagagcc
    11881 gacatctgcc ttcatttgac gaagcgcttc taagaatggc agactctcaa tgtctcccac
    11941 agttccacca acctcggtaa taatcacgtc agaatctgtg gtcgtagctg cgcgcttgat
    12001 cttctccttt aaggcatctg taatgtgtgg aataacctga acagtcgctc caaggtattc
    12061 acccttacgc tccttacgaa gcacctcact gtagatttta ccagttgtca catttgagta
    12121 tttattaaga ttaatgtcaa taaaccgttc gtagtgacca agatccaagt cagtctctgc
    12181 accatcatca gtgacataga cctccccatg ctgataaggg ctcattgtcc caggatcgat
    12241 attaatataa gggtcgaatt tttgaatcgt tacctttagg ccacgatttt tcaataaacg
    12301 tccaaggcta gccgctacaa taccttttcc gattgatgag accactccgc cagttacaaa
    12361 aatgtacttt gtcataacac tcctttatcc ttttgagtta agcctgacta actcgttttt
    12421 atttttaaaa gatcgtccta ctttagctag taacgattgg gggctaagct tcccataagg
    12481 ctaagccatg agaccagtaa ccaaggctaa gttattaaaa caaaaatagc cccctattaa
    12541 ctagggagct tacctgacct cttaaagagg tgcccgatta ataatataaa ctataagagg
    12601 acatttgtca aatattactg ttgcttttag aggctagcga tactcctgct attcctcctc
    12661 ttcctcatct tcttcgtcct cttcattgag gtcaacctct tcaaaatcgt cctctggaat
    12721 gatttcattg agctctgaat cgtaggactc tacttcagat ttttcatcgt ctggatcttc
    12781 ctcgtcatat tcaatatcag atgattcacg aacaaaatcc tcatcctctg gatcatcagc
    12841 gctatagtca atagcgtcct catcaccgtc catgaaggca ttgacacgtt tcttcttgcg
    12901 ttttggtgcg ccgtcttctt catcttctag ggtgatgatt tcctcatcaa tctcatcaat
    12961 agcataccat gaacgtagac cccatttatt ttcaccaagt ggaataaagc taccatctgt
    13021 attgagatca gtgtaaaaaa atggtaaagc atatcgaata tcagcgtcag acttgcctag
    13081 gtaattttga atctcattaa ccaaatcgct aaaatacatg tcattatcgc gaccacgctc
    13141 ttctaaaata gcacgagcaa cttcaatcat agaaagttcg cttatttctt gtcctgcaaa
    13201 tacatctaat ttcaaggcag ttctccttat tttatcattc tcccctattt tacgctaaaa
    13261 ataccgattc gtcaaagctt ttatcaggga agaacagtat tctttttacc cacttctcag
    13321 ccagcaagaa caaagcctag cagcaaccag cttgattgct cctaaacgcg ataacagaag
    13381 catttcaaag agaagtgtta actgtttgcc tttaaaccat gaagcaacag caaaacaaga
    13441 ccaagtgctt gcttagtctt gcttgtctat atcataacag cttattttgc ttttgctgag
    13501 cttgtaatca cttctacagc ttttttcata acaatgtcat gctttaacat atcagctgaa
    13561 agcaatgagc gaacctgctc aactggcatg ctatactcag ctgcaaggtc gttaatttct
    13621 ttttcaatct catcgtctga agcttcaaag ccctctgcct ttgcgatagc ctcaataacg
    13681 agattagttt tgacacgctt gtctgcctct gcttcatgct gcttgtgaag atcttcttga
    13741 cttgtgccag ttagctggaa gtacatatca ggtgaaatgc cctgacgctg catgctagcc
    13801 ataaattcat taacggaacg gtgaacctcg tcatgaacca tttcctctgg taattccaca
    13861 atttcagcat tctcaacagc taactcaata gcagcaccct ctagagcgtc atcataagct
    13921 gcttcctttg aagcctcaag ctctttacga tacttagcct ttagctcatc aagtgtttca
    13981 acttcctcgt caatatcctt tgcaagctca tcgtcaagct caggtacttc ttttgccttt
    14041 acctcatgaa cagttgccac aaacttagca gccttacctg caagatcttc agcttgataa
    14101 ttttctggga aggttacatt aacctcaaca gtgtcaccag ccttagcgcc aactagctgt
    14161 tcctcaaagc ctggaataaa ttgtcctgag ccaagctcaa gtgagaaatt gtctcctttg
    14221 ccgccatcaa attcaactcc atcaacagag cctacaaaat caataacaac tgtgtcacct
    14281 tctactgctg cttcttcttt gacaaccagc tcagcaagat tgttgcgctc gcgctcaacc
    14341 tttgcgtcaa cctcctcatc agtaacctct tttgaagcct caacctcaac agtaaggtct
    14401 ttgtaatcac caagcttaac ctctggtttt gtgacaacct ctgcagtaag tgtccattct
    14461 tgacactttt ccatagaaac cacatcaatt tttggctgtg caacaacatc aagctcaagc
    14521 tctgcaacag caccttcata ggctgctggc agcacaatat tcaaggcctc ctcataaaga
    14581 acctcttcac caaatctttg atcaaaaaca ggacgaggca tgtgaccctt acggaagcct
    14641 ggtgcattta aatccttttt aattttatta aaagcttgat caagagcggg cttgatttta
    14701 tcttgactaa tggtaaatgt aatcacgcca cgatttgtag ctttgttctc aaatgatgta
    14761 gacattaagt catttctcct taaaataatt tagatacacc tcattctatc atattaccaa
    14821 gtgtttttaa agttttttat gcgtgaaagt agggacaggg tttccaaata tcagactctt
    14881 aactgaacca ttaccaaaaa cctcatcagc ttcaaagaaa aagagactgg aacaaaagtc
    14941 tgcctccaaa ataaaacaaa cgaacaagac ttgttttctg agatcccaaa aactagtctt
    15001 gttcgctttt taattattta gactgggtaa taaaatacat tagctaagac tttttaacat
    15061 gcaactcttt ttgtcccaga gtccaaacag tccttaatct gtaagccaga tagttacgct
    15121 ggaagtagga cagctactga tttcttagct agatgaccgg taatgttgtg attggaaaca
    15181 tgataaactg tgccagtcac tgcgtctttg tagtcaccgt cagctagggt tgttgtagaa
    15241 gaaaagtctt tatcaacgat ggttaggttg gtgataacag cacccttttg accgcgttca
    15301 atcatgacta gaccttggtc cataccagga ttgcgaatat attctgattg accattcatc
    15361 ctattgcgga attgattaat cgcaacaatg gttggatcct taaacaagtc actgccggca
    15421 tcaccaattt ggctttctcc agggaagcgt ccattttggc cgccaccgcc acgaggacgt
    15481 gaaaagaaga gcggtgctcc ctcattacga gcagcaataa ttccccagcc aagcttaatg
    15541 tcctcatctg ttagcttggt agactcttca tcatcgttag cataggtatc atgagattct
    15601 acccaagtga ctaacttgtc ctctgaaacg ccatgcactt ggaaattcac caaatcccaa
    15661 tctttcacat agccttgacc tagcacttta cggattagct taccatagtt tgacgctgtc
    15721 actcccatga tattgccata gcctgcttcg ttgcaagcat caccctgtaa aatttctcca
    15781 tattggaatt tagcaccatt gttaagaata accttccaga aatcgctgtt atgctcacct
    15841 ggtaattcga tatgctttgc agcatcatac ctaaagccat ctgctccatc agctactgct
    15901 cgttttagat aattcagcat gtattcttgg acagctcgat tttgcgtgtt gaaatcataa
    15961 agtcctagca aggatttttg ggttatttga taacgatcgt tgaagttgac gattttgtca
    16021 tttccatgtg tccagttatc tatggctgtg atcttagggc taactgcctt aatctcagag
    16081 gttgtatgat tcaaaacagc atcaacaata atattgatcc catatttatc agcctcctga
    16141 gccattgcct taaattcctc ttctgttcct aattggtagt tcccgatagt atagtctgtt
    16201 ggctgataat ggtaatacca gtttttcaag tccttactac cgccagctcc ttcaatgaca
    16261 gcattaatag gtgaggtttg aatactagtg tagccagctt ccttaatggc actcatgttt
    16321 tctttgatgg tgttaaagga ccagcaccaa gcatgtaaaa tagctccgtc cttcatggct
    16381 accggttgat tatcggactg cacctcctga gcactagcaa ggttagctgg ggctagagga
    16441 gccaagcctg aaagtaccaa gccaagggtc aagctggtca ctgatagagc tttgagaaat
    16501 ctttttgtct tatgtgttac catatgtaaa ctccgttctt tctgcgaaat cgctttcgtt
    16561 ggcgcttaaa aaaataagat gattctctgt actgtttgca aacaaaaata ggacctatga
    16621 gagaagtata acatataaat ttcggtatgc ataccatttt tagcaaaaaa ttagtgattt
    16681 ttttaatttt tatttccttt gctaaagcct ctaaaaccaa tcaaaataat gttgcataag
    16741 tatttgcctt ttatttatct cataatcaga ctcattcgct ctaatctttt gcacatgtta
    16801 atgtcattta tttgcagacc tacgcaacca attgcacaga gctttgtttc cttcgtcaga
    16861 aaaacctcaa taaaacataa acaagaagcc attactcttc ttgataatgt ttggtgatct
    16921 attttcaacc aggacttttt ttggtaaact agctacgata gaaaggagtt gccatgacgt
    16981 ttatattaac atactttaat cagctacacc tagaaaatat catggtgctt gtgttttcta
    17041 aattagtgtc aatcacctta ttattgattt tctttgtgat cttcaaaaaa atcacgacag
    17101 ctttatttga aaaggcaatc gccaagtcat tttcctattc aagacaaact gaagcaagga
    17161 aaaaaacctt atccaagctc cttcacaaca ccctaaatta tgttttctat tttcttctca
    17221 tctattggat tttgagccta cttggtattc cagtatctag tcttttagca ggagcaggaa
    17281 ttgctggtgt tgctattggg cttggggctc aaggcttctt gtctgatgtg gtcaatggct
    17341 tttttattct gtttgaaaat caatttgaag taggagacac cgtcaccatt gcaggcattg
    17401 aaggaaccat ctccagcgtt ggtattcgaa ccactcaggt gcgaggcttt gatggcacac
    17461 tacattttat tcccaaccgc aatattacag ttgttagcaa caaatcacgc ggcaatatga
    17521 gagctttgat cgatattcca ctttattcct caaccgatct agagcatgtg acccaaatca
    17581 tcaaggctgt caataagcga gaggtgccaa atttcccaca aattgtcgga cagcccaaca
    17641 ttctaggacc acaaaccaat cccaacggac aattcacctt tcgcgttagc atttttactg
    17701 aaaatgggca gcaatttacg atttactata gcttttataa gctctatcaa gaggccttac
    17761 taagggaggg tatcaagcta ccaactgcat ctgccatatc acccttagcc tagcagtaaa
    17821 aaccattgct ttcttagcat acaaaagccc tatcccgcag ccaggtcatc agacttagac
    17881 tgctagatag ggctatttct tttggctctt atttccgaat aggatcaggc tgatacctgg
    17941 ctcttacacc accaattaat ttgggccgac ttgctaaggc agtcacatga gcaccaccaa
    18001 gctctcgctg aataggcaca agcggcacct gtacacgctt aacatgcata ccaattgagg
    18061 tatctccaat gtcaaggcct gcatgagcag caatggcttc aacctcaact ggctgcttca
    18121 tgtatttgaa ggctgctaat tgaccacttc ctccagcatg caagctaggc agcacattga
    18181 ctatttctag ccgatattct tcagcaacac tttcttctaa taccaaggca cgattaatgt
    18241 gctcacaccc ctgaaccgct aaatgaatcc ctctgaacga caattcctcc aatataagct
    18301 tcacaataac ctcgcccacc tctaagctag aatgctggcc aatacgacca ccaagtacct
    18361 cgctagagga cagccctaag acaaacagtt gccctttttt gatagcacta cgctccacaa
    18421 tatcaagcaa gatagagcgt gcttcttctc tcaatacttt taaattcatt gaatcacctg
    18481 cttaatcatc tgacactttg accagctgtt ttttgacccc taaatacagc agatagccta
    18541 cacctatgcc aagggtattt tgagcagcat tccccgaaat ttctgaaata gcagcgccca
    18601 taccatacat tggaatagct gcaagaaaat acagaccaac cattatcaca gaagcaaggc
    18661 ccacgccaag aaagcgatgc ctgccaggca agcctgctaa gtagccctga gccccatgag
    18721 caacaagact aatcagcatc caattggggt aacctgagat caaatcaagc aaaaaagctg
    18781 ataagccccc aacaagcata ccctcctttt tcccaagaga aaaggcagtc acatacaccc
    18841 ctgcatctaa aagacttaaa aaacctgtcg gcgtggcaat actcacaaac ctgcccagga
    18901 caactgtcag ggcagtcaag atagacacaa gagctagctc tcttgtctgt ttcatattta
    18961 tcataagaca actccataat catttgactg ttgaatggct tcaaaaacaa ggtctttagc
    19021 ctgctcaaca gccctaagcg gtgaatatcc cttagctaaa taagcagcaa ttgcagctgc
    19081 aaagctacag ccagccccac tgttttgttt ggccaagact ggcttttcta aaaagcacag
    19141 ggtttttgcg tcataaaata gatctagggc aactcgttga tcaaaacgat tcccaccctt
    19201 gatcacaacc ctcttagccc ccatctcata aagctttttt gccgcttcta ccatttgctc
    19261 cctgctatta atagcaagcc ctgccaagcg ttctgcttct cttaggttgg gagtaatcac
    19321 tgctgttaag ggaaaaagag agcgcaaagc ctgtgtcatt tccacaactg tctgatcttg
    19381 attttcctta aatactaaaa caggatctaa aacaacaggg atatcctttt ttagctctaa
    19441 aaacagggcc acctgctctg ctatttcagg tcttggcaaa agaccaactt tgattgcctg
    19501 aaaaggaata gctgctaagc tagacaactg ctttgccagc aaatcagtcg caacagggtg
    19561 aatgctgaaa cctttagcat cacagcttgt taagcaggtg atagctaaaa atgcaaagct
    19621 atcgagctga tgaagcactg ccaaatcagc ctgcaaacca ccaccgctga atatatcact
    19681 cccagcaatc gttaatacct tattcttcat aaatgatttc cttcaaataa agaccattac
    19741 cagccgctgt cggtccagct agctgccgat tcttactctc taaaacgagc ctgatttgtt
    19801 caatgggcaa ccgaccattg ccgatcttaa gcaaggtccc aaccatattt ctaacctgct
    19861 tataaagaaa gccattccct gaaaacgtaa aaacaagaaa accagtttta gggtcctgag
    19921 tgagggtagc tgctgtaatg gtacgaacct tatttttaac agaggttccc gcagctgtaa
    19981 agcctgtaaa atcatgcgtc ccaaccaaat ccttaatcgc agcctgcatt ttcgcaatat
    20041 ctaagggata agggtaatgg gtcgcataat ggcgcatcat aggattttta ggacgaccaa
    20101 tatccactaa gaattcatag gttttgaaat gcttatggta gcgagcgtga aaatcatctg
    20161 ctgcaatctc cagactgatc acatcaatat catctggtgt ctgggtatca agtgcaaagc
    20221 gaagcttttc agggtctctt ttttgctcca aatcaaagtg aatcacttga ccataagcat
    20281 gcacacctgc atctgttcta ccagctccat gaatctgtat cccttgacca cctgtcaatt
    20341 tttgcagggt cttttcaatc tcttcttgta ccgtacgtgc ctgactttgt ctctgaaaac
    20401 cagaaaataa ggtcccatcg taggaaataa ttgctttata tcttgtcatg ctattattct
    20461 accatttctt ccagccatca gaaaagagca tttacggctt ttgtccccat acagttttcg
    20521 attagctttg ataatcaagc ttgatttgac gccaacaggc aaaaaaaggc tactgacaag
    20581 gactagcttt tctgctataa tttctctaat attcaataag tagactggag agcaaatgaa
    20641 ggtaacaaaa tttggcggca gctccttagc atctgcccag cagttagaaa aggtcttggc
    20701 tattatcaag gacgatcctg agcgtaaaat catcgttgtc tccgcaccag gcaaacgatc
    20761 ccctacagac acaaaggtga ctgatgcact cattgcttat tacaaagcct acgtctcaga
    20821 ccgtcattat cacaagcatt tggaatggat tatcaatcgt taccaacaaa tctgtaatga
    20881 cctaactcta gatagcaaaa tcatcaccca aattaaagct tccttagagc aattggcacg
    20941 gcttccaaaa gaacataatc cctatttata cgataccttt cttgcggccg gtgaggacaa
    21001 taatgctaag ctagtagctg cctacctcaa ggcaaatggc ttaactgcaa gctatctcca
    21061 ccccaaagat gcaggtctaa tcgtaagcag tgagccacag catgcacgtc ttcttccaat
    21121 cagttacgat aagctagagg ccttaaagga tcatgatgac attcttgtta ttcctggatt
    21181 ctttggtgtg acaaatgaaa accagatttg taccttctca cgtggtggct ctgatattac
    21241 cggctccatt attgcagcag gagtcacagc tgacagctat gaaaatttta cagatgtcaa
    21301 tggcatcttt gctgcccacc ctggtgttgt taagcagcca cagacgatca ctgaattaac
    21361 ctacagagaa atgcgcgagt tagcctatgc tggcttttct gtcctccatg atgaagcatt
    21421 aatccctgct taccgaggga aaatcccaat cgtcatcaaa aacactaaca atcccagcca
    21481 cccaggtaca acaattgttc ttgagcacca gaggaaatcc aatcccgttg tcggtatatc
    21541 aggtgatgat cactttgtca gcattaacct atctaaatac ctcatgaaca gagaaattgg
    21601 atttgggcgc aagctccttc agatattaga ggacctcaat atcagatggg agcacatgcc
    21661 tacaggtatt gatgacctat caattgtact tagagaaaga gaattgaccc ccatcaaaga
    21721 agaagaaatc cttcgcagac ttgtccagca attagaggtt gatgaggtgt ccatcaccag
    21781 gaacctttct attatcatga tagtcggtga aaacatgaaa agtcatattg gtgtcacatc
    21841 tgccgcaaca aaggctctat ctgaacatca tatcaatatt gctatgattt cccaaggctc
    21901 aagtgaggta tctgtcatgt ttgtcatcaa tagcaccgat gaaaaaaagg ccattagagc
    21961 cttatatcaa acctttttta gccctgatcg acccctgtaa agctccatat aacatctctt
    22021 gttaacacca agcttcaaaa acagctcaca agctagacag tactcctagc ctatgagctg
    22081 ttttgatgat ctaaaactat caagattaag catcggtagt aacgacttaa tatgctcaca
    22141 gctatcataa actctagctt taccttattg aggaaaagaa aaccagtttt cacctcagct
    22201 aagattaaca acaagcgatt aagcacttgc taaaaacaga tagacttcaa aagtgagaca
    22261 tatgtataat ttctaccaga tctaaataaa tatagcagca gagcaccgag tttaataagc
    22321 catttctgac atgataaact cgccaagctc tccacagatc aagatttgcc ttatcaattg
    22381 atacaacagc cagcattctc aaagatgcac aagatccatc acagtctagc catctccctg
    22441 cacagtaag
//
LOCUS       DARYXW010000025        22432 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.025, whole genome shotgun sequence.
ACCESSION   DARYXW010000025 DARYXW010000000
VERSION     DARYXW010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22432
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.025"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(111..533)
                     /locus_tag="TV191_000785"
     CDS             complement(111..533)
                     /locus_tag="TV191_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507318.1"
                     /translation="MEHSQLEWEDVSQYEEVKGYGQQVWKRQGTYYLVTNEGGIAEQR
                     VVYELPYDLFELLEQGKRNLGEIAFKLRYDCWPPTEEEKIASDKAFLQRSPIALIADP
                     TSWELFTQEELRKLIPIAEQKWIDWKGKLPDDYVSPLK"
     gene            complement(856..1116)
                     /locus_tag="TV191_000786"
     CDS             complement(856..1116)
                     /locus_tag="TV191_000786"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507319.1"
                     /translation="MDNNNCFQYTQRLRELIELEYPKQKNYSGILRDLYVLTNDIDNN
                     RIVGNINFSSLARQFVDDTTQYDSPILKTLKDLEVCLNRKRR"
     gene            complement(1131..2939)
                     /locus_tag="TV191_000787"
     CDS             complement(1131..2939)
                     /locus_tag="TV191_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507320.1"
                     /translation="MSYNIKYDEITSLQQSTQTTISAWGDGITSIQTALSALIGDSRL
                     QGQTASSIKSYLSEVHGTLLQTLQSLMNDYSASLLLYKDGYYQIDSNSHAQLPGQVFK
                     TLQSELRLSQAHLKDQLELLQNTRAKLSDLVHYSGVSHAKTVVDYSELITDIHRLDEA
                     IIQYESNHASQDLAAFKELLASTKALIAEYSSKPKRAGSYQVGDIGQLNTIKRFATAY
                     QGVARHLETNAKRLQAAQERDHARFEAVAAEDRAKQGWIDLALSLVTIAVGVAAIVMT
                     AGAATPLVVGAFVVGSGTVAYGASNLYEAGHNIYLGSVGDGLTVATNPLRDTLFMGND
                     RLYHQIGGLFTTASAALILIGQTKSVAKGLTEFTIGEVGGFIGGQASYHGTKLLGGSE
                     QDAQRATLVGNILAGYAASSAARRFSLNEPIAARVTKPTYNHQQLLKNLENSRLARES
                     SNFGGYIKKESVTKYPTQIDSKVTVGAKENLPGWIADSFTDSHYRTVITGEEITLYRT
                     FGGASDAGGGFVTTVPATNRIQAKIDTALLPEWKNTRQYEAVIKIPKGSQLNIGKVAP
                     QTVKSSGTTLIGGGDQVLLPNRWPLEWIQEIRIVPN"
     gene            complement(3580..4479)
                     /locus_tag="TV191_000788"
     CDS             complement(3580..4479)
                     /locus_tag="TV191_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEL1507321.1"
                     /translation="MVLFTGKTVEEAIEKGLQELGLSRLKAHIKVISKEKKGFLGFGK
                     KPAQVDIEGINEKTVYKADKKAVRSVPEEINRQNAPVINPDEVELEEMKAVRSQDRRA
                     AESDAHQPTGPLSTAQSAPTQSKAQPVSSAAGASQLDPAAADMSKDIELAAQEISDYV
                     TKIIYEMDIEASIERTNNRRQINLQIETPEAGRVIGYHGKVLKSLQLLAQNFLHDRYS
                     KNFSVSLNVHDYVEHRTETLIDFTKKVSKRVLESGQDYTMDPMSNSERKIVHKTVSAI
                     DGVESYSEGNDPNRYVVVSLIHD"
     gene            complement(4491..5300)
                     /locus_tag="TV191_000789"
     CDS             complement(4491..5300)
                     /locus_tag="TV191_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002267318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEL1507322.1"
                     /translation="MKKRVKTAALVPLVLLLVACGRGEVTAQSSSSWEQLVYFFAKAI
                     QWLSFDGSTGIGIILFTIMIRLLLLPLFNMQIKSGQKMQDIQPELKALQKKYAAKDTA
                     TRMKLAEESQALYKKYGVNPYMSLLPLLIQMPVMFALFQSLTRVAFLREGTFLWVELA
                     RHDHLFILPILAAVFTFLSTWLTNLAAREKTAMITIMTYVMPVFIFFMGFNLASGVVL
                     YWAVSNAFQVVQLLLFNNPFKVIAERQRLADEEKERRAKERRARKRAMKRK"
     gene            complement(5284..5643)
                     /gene="rnpA"
                     /locus_tag="TV191_000790"
     CDS             complement(5284..5643)
                     /gene="rnpA"
                     /locus_tag="TV191_000790"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEL1507323.1"
                     /translation="MKKSYRVKREKDFQAIFKLGQSMANRKFVIYHLKGEHKHFRAGI
                     SVGKKLGNAVTRNAVKRKIRHVLMELGDHLKSEDFVVIARRGAEELDYQAVKQNLHHV
                     LKLAKLLEEGFEIEKKS"
     gene            complement(6135..6875)
                     /locus_tag="TV191_000791"
     CDS             complement(6135..6875)
                     /locus_tag="TV191_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1507324.1"
                     /translation="MLNIFILEDNLIQQSRIEAIVASILEEGRIPHNQLEVFSNPQKL
                     FDSIQERGDHQLYFLDIEIGDKSRSGLELASDIRQKDPNAVLVFVTTHSEFAPISFRY
                     KVSALDFIDKAVDSQQFKERIEECIRYTYEMMSSRQVEEMFLFETPQTRLKLPYKDIL
                     YFATATTPHKVCLWTQTERLEFYGNLSEIHAVAPKLFLCHRSYLVNLDNVVRIDKAKQ
                     LVYFENGDSCMVSRLRMKQLFEKWKSFR"
     gene            complement(6879..8177)
                     /locus_tag="TV191_000792"
     CDS             complement(6879..8177)
                     /locus_tag="TV191_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEL1507325.1"
                     /translation="MLGMSFFYALIFVNSWVIFSTFSGIKLAVRSLLLVGACFVVANL
                     LLDHVLLVDQLVFVAVSVGFAPHKKASEHLFNGLFAIMIVELLFRIIGSFLLPAVLGY
                     SIHQINNDIGLLMVCHALVLPAFYLFSYIFSVDLTLIKFISEDKLKKWVFWMNAALLF
                     YYVMVHCMINIQGDFFKIYFRYRSVMIFLYLMLLIWVIVKLDRFAKDQLSQRLALAQK
                     ERVAYLEKHNQYIERLCREIRAIKHDSENILISLKDSIDSGDIAAISKVYQTVIQESA
                     SSIRQLTPELSALDNVQDSVIRSLLHAKLLEAKLQGIAVYIDIPETLASSSVRLLDVI
                     VLFKVVIDNAILSAKGSSRPFLSIAYFNQDGKRFFIIENSTRLKRVDIAKQFDASRLE
                     LGSHAHKRLLQFSAVLERYPHITFSTKSDHYRLRQLLEMR"
     gene            complement(8189..9535)
                     /locus_tag="TV191_000793"
     CDS             complement(8189..9535)
                     /locus_tag="TV191_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEL1507326.1"
                     /translation="MTDIYYLFLLLSLMIYYVTEISIFSFLSDIKLALWKQIFVLTAA
                     LFLNQFALLPPLIIDPLLLLAVLALEKRPCFSLKALFLAFVPGVFVDLLSRFILAIVL
                     PYIFSVNGSYVRHLVLDFIAYVMIFPSFALINYFVGKDYKQIVKADRFDKASSFYSLF
                     LLFSLAYYIDLFMILGFTDPFLDLKSPIMMSTSYKVLFLIFTLLLIYLLSYFNHQSKE
                     FLKQELKKEQQAYIANLETYGKHLEKLYKGVKVFQLVYLKRLERLGQAIDSGSVSDVQ
                     TVYAQTVDEATDYWDDKHYNISKLSKISVSSIKSLLSSKIIKAEKAGIALSLEVPDRI
                     RDSYISELDLLLLVSIFCDNAIEAALETAQPAVAIAYFLSDDQQIFTVTNTTKDERVM
                     ISRIFEEGYSSKGSGRGIGLSNAKRILQKYPELSLRTRSHDYQFSQTLIMPKIEKE"
     gene            complement(9980..11425)
                     /locus_tag="TV191_000794"
     CDS             complement(9980..11425)
                     /locus_tag="TV191_000794"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEL1507327.1"
                     /translation="MSKPIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGDFIIRIE
                     DTDRKRHVEDGERSQLENLKWLGIDWDESPETHERYRQSERLALYQQYIDQLLAEGKA
                     YKSYVTEEELAAERERQEAAGETPRYVNEYLGMSAYEKAAYIAEREAAGIVPTVRLAV
                     NEAGVYKWTDMVKGDIVFEGGNVGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPVFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYM
                     PEAVFNFIALLGWNPGGEAEIFSREQLIALFDEIRLSKSPAAFDQKKMDWMSNEYFKH
                     ADLGAVYALCKPFLEAAGRLTEKAEKLVELYQPQLSSADEIVPLTDLFFSDFPELTAK
                     EKEVMAAETVPTVLKAFKEKLEAMSDEDFKPENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPNTIYLLGREQSIEHIANML"
     gene            complement(12027..12740)
                     /locus_tag="TV191_000795"
     CDS             complement(12027..12740)
                     /locus_tag="TV191_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00266 family protein"
                     /protein_id="HEL1507328.1"
                     /translation="MAYNRMTYTIDSSMQFPLVEIDLDMGESVFLQKGSMVYHTPSIS
                     LNTKLNGRGSGLGKLVGAIGRSMVSGESMFITQAIANDVSGKLALAPSMPGQVIALEL
                     GVDQYRLNDGAFLALDGSAHYTMKRQKLGKALFSGQGGFFVMSTQGEGTLLVNAFGSI
                     KKITLHGDSMTIDNSHVVAWSQDLDYDIHLENGFMQSIGTGEGVVNTFSGYGDVYVQS
                     LNLQQFAGVLQSYIVTGGH"
     gene            complement(12868..13374)
                     /locus_tag="TV191_000796"
     CDS             complement(12868..13374)
                     /locus_tag="TV191_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEL1507329.1"
                     /translation="MSYFERFLSANEAYVALHGTAHLPLKPKTKVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRITDDMLRSLVISQQQLGTREIVVLHHTDCGAQTFTNEAF
                     TAQLHDTLGVDVSDCDFLPFTDVEASVREDMAILQQSPLIPKDVVISGAVYDVATGRM
                     SQVAMPKS"
     gene            13757..14035
                     /locus_tag="TV191_000797"
     CDS             13757..14035
                     /locus_tag="TV191_000797"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507330.1"
                     /translation="MKQTKIICLLAAAAVLTLGPISTGQTQPQTVYASQVSGDSCIDL
                     GNGWFKCPKDIGGWDILFNQDYQAPSRSPFFTWISGWFNFIWQWFKSF"
     gene            complement(14196..15557)
                     /gene="radA"
                     /locus_tag="TV191_000798"
     CDS             complement(14196..15557)
                     /gene="radA"
                     /locus_tag="TV191_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEL1507331.1"
                     /translation="MAKKKARFICGECGYQSPKYLGRCPNCSAWSSFVEETEVKDVKN
                     ARISLTGEKSKPIKLKHINGVRYQRIQTEMNEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSIQLADKGTVLYVSGEESAEQIKMRSDRLGQTDNDFYLYAETNMQAIRAEIE
                     AIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELLQLAKSNHIATFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFDMQSGGLVEVLNP
                     SQVFLEERLDGATGSAVVVTMEGSRPILAEVQALVTPTVFGNARRTTTGLDFNRVSLI
                     MAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTNPQEAFLGE
                     IGLTGDIRRVTRIEQRINEAAKLGFTKLYAPKSSLQGIDLPKGIEVVGVTTVGEVLKA
                     VFT"
     gene            complement(15624..16070)
                     /locus_tag="TV191_000799"
     CDS             complement(15624..16070)
                     /locus_tag="TV191_000799"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEL1507332.1"
                     /translation="MTRIRGFELVSGFTDTDLLPKRETAHAAGYDLSVAEETSIAPGE
                     IVLVPTGVKAYMQDGEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPANEGHIFAQ
                     MKNITDQTITLSAGERIVQGVFMPFLIADGDQAGGERTGGFGSTGG"
     gene            complement(16272..17039)
                     /locus_tag="TV191_000800"
     CDS             complement(16272..17039)
                     /locus_tag="TV191_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HEL1507333.1"
                     /translation="MIDLQEILARMNPNQKINYDRVMQQMTKVWARESIRPRILMHVC
                     CAPCSTYTLEYLTQYADITVYFANSNIHPKDEYHRRAYVTQKFVAEFNDKTGNSVQFI
                     EADYVPNEFVKTVRGLEKESEGGDRCRVCFDYRLDKTAQKAVELGFDYFASALTISPH
                     KNSQTINDVGIDVQKVYTTKYLPSDFKKNNGYRRSVEMCEEYDIYRQCYCGCVYAANI
                     QGIDLVQVKKDAKAFMADKDLEADFPRIRFSYAGKEI"
     gene            complement(17201..18997)
                     /locus_tag="TV191_000801"
     CDS             complement(17201..18997)
                     /locus_tag="TV191_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1507334.1"
                     /translation="MKILRFFWFYFKRYKLSFVVIFFAIVLATYLQVKAPVFLGDSLA
                     ELGEWVQRYYKAQALSKMTGQPLVEPSMAPFRTVMGKLLLAYLFTAVANLIYSLLFTR
                     VISHSTNRMRKGLFGKLERLTVGFFDSHKDGAILSRFTSDLDNIQNSMNQSLIQVLTN
                     IALYIGLVLMMFRQDSRLALVTIASTPVALILLVVIITMARKYTDLQQKEVSALNAYM
                     DEKISGQKAIIVQGVQQDAIDGFIEHNERVRAATFKGRLFAGLLFPVMNGMSLLNTAI
                     VIFAGSTIVLGDKSMSTAAALGLVVTFVQYSQQYYQPIMQIASSWGELQLAFTGAGRI
                     QEMFDEKEEVRPEHAPVFTALKEGVEIKHVDFGYLPGQKILSDVSISASKGKMVAVVG
                     PTGSGKTTIMNLINRFYDVDAGSITFDGRDIREYDLDSLRQRVGIVLQESVLFSGTIA
                     DNIRFGNQTISQKEVETAARATHIHEFIMSLPDGYQTQVSDDENVFSTGQKQLISIAR
                     TLLTDPQVLILDEATSNVDTVTESKIQKAMEAIVAGRTSFVIAHRLKTILNADEIIVL
                     KDGKVIEQGSHHELLRQKGFYAELYHNQFVFE"
     gene            complement(18997..20706)
                     /locus_tag="TV191_000802"
     CDS             complement(18997..20706)
                     /locus_tag="TV191_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1507335.1"
                     /translation="MLRNAVMKYKWYAALSLVMISGVVASALLQPHYLKDVLAAIMEN
                     DQTRIAEVGFWLLVIAGIGLVSGAVNTILSAKIAQGVSADIREQTFRKIQSFSYANVE
                     AFNAGNLVVRMTNDINQIQNFVMMLFQILLRLPILFVGAFILAVQALPSLWWVLVLVV
                     VMTMVVIGLVMSQMGPRFGIFQRLMDRINQIAKENLRGVRVVKSFVQEKSQYDTFKEA
                     SNDLLGLNLFIGYGFSIMQPILMLVSYMAIYLSLYLVSGLVKTDPAVIGNMASFMTYM
                     GQISFAITMVGFMGMQASRALTSIGRIREILETEPAMTFVNHEQEELTGSIVFDDVSF
                     TYPNDSEATLKHISFEVEPGQMVGIVGATGAGKSTLAQLIPRLFDPQEGQILIGGKAL
                     PSISQETLRDTVSIVLQKAILFSGTIADNLRQGNPYADQLALENAARIAQAKEFIDRM
                     DAGYQSEVEERGNNFSGGQKQRMSIARGVINNPKILVLDDSTSALDAKSEKLVQEALN
                     KELKETTTVIIAQKISSVVKADKILVLDNGRLIGEGTHAELVASNPIYREIYETQKGR
                     EEN"
     gene            complement(20699..21148)
                     /locus_tag="TV191_000803"
     CDS             complement(20699..21148)
                     /locus_tag="TV191_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEL1507336.1"
                     /translation="MPRIIAELRELTHQVEQISEEIAKKYDLQHLAGPQGHVLVFLHC
                     HQDRDIFVKDIEKELQISKSVTSNLVKRMEKNGFIRVVASATDKRCKQVVLTSAGRAK
                     LPVLKECRRDIERYFFKEISREELLTVKKVIDQLKQNIRAYKGDTDA"
     gene            21358..22377
                     /locus_tag="TV191_000804"
     CDS             21358..22377
                     /locus_tag="TV191_000804"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEL1507337.1"
                     /translation="MPKQKVAILGPGSWGTALAQVLNDNGHEVRLWGNIPEQINEINT
                     RHTNSHYFKDIVLDEAIKATLDLKEALADIDAILFVVPTKVTRLVAKQVAQVLDHKAI
                     VMHASKGLEPGTHERLSTILEEEIPAQLRSEVVVVSGPSHAEETIVRDITLITAASKD
                     ITAARYVQTLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGYGDNAKAAVI
                     TRGLAEITRLGVKLGADPLTYSGLSGVGDLIVTGTSVHSRNWRAGAALGRGEKLKDIE
                     NNMGMVIEGISTTKVAYEIAQELGVYMPITSAIYKSIYEGADIKESILGMMSNEFRSE
                     NEWHT"
BASE COUNT         6671 a         5445 c         4219 g         6097 t
ORIGIN      
        1 tggcattggc ttcaaggtga cgagctactc cctgataagc tgtcgcaggc taattattaa
       61 gaacatgctt taaaatagca gagctaatct cggctccgct atcttaaaca ttatttcaaa
      121 ggactgacat aatcatctgg cagttttccc ttccaatcta tccatttttg ctctgcgatt
      181 ggaatcagtt ttcttagctc ttcttgggta aaaagttccc aacttgttgg atctgcaatt
      241 aaggctattg gggatctttg taaaaatgct ttatcactag ctattttctc ttcttccgtt
      301 ggtggccaac aatcatatcg caatttaaaa gcaatctccc ctaaattccg ttttccttgc
      361 tccaataatt caaataaatc atacggcagc tcatatacta ctcgctgctc agctatacca
      421 ccttcattag tcactagata gtaagttccc tgacgcttcc acacctgttg accataaccc
      481 ttgacttcct catattgact aacatcttcc cactctaatt gactatgttc catgtatgtt
      541 ctcctttact tgtactgata tctttcataa ctccctctgg catatcaccc ggataagtac
      601 gacctccagg tcgccaccag ctattagcac ccttttcatt accacttgga atagaaatcc
      661 ctttctccga aacaacctct ggtgaaacat ctaagcgata gagcggatca ttgccaagat
      721 aaccctcgtc gaagccgagt aagctttcat aaaagattga tgcatagtca gcttactctt
      781 gttcctcctt tcttcagttt tttatcataa tttcatctta aaatttaatc aattcgagca
      841 atctaatctc actcatcatc tccttttcct atttaggcat acttctaagt ccttcaaagt
      901 ttttaaaatt ggactatcat actgtgttgt atcatcaaca aattgtctag ctaaacttga
      961 aaaattaata ttcccaacaa tccgattatt atcaatatca ttagtcaaaa cataaagatc
     1021 tcttaatatt cctgaatagt ttttttgctt gggatactca agttctatta actctctaag
     1081 cctttgtgta tattgaaaac agttattatt atccataaat ttctcctttt ttagttagga
     1141 acgatcctta tttcttgaat ccactccaat ggccaccgat tgggaagtaa gacctgatct
     1201 ccacctccaa ttaaggttgt tcctgaagat ttaaccgtct gtggggcaac cttgccaata
     1261 ttcaattgac tcccctttgg tattttaatt acagcctcat attgtctagt atttttccat
     1321 tctggaagta aagctgtatc tatttttgct tgtatacgat tagttgcagg caccgttgtg
     1381 acaaaaccgc ctccagcatc tgacgcccct ccaaaagtcc tataaagtgt tatttcctca
     1441 cctgtaataa ctgttctata gtgactatct gtaaatgaat ctgcaatcca accaggaaga
     1501 ttttccttag ccccaactgt tactttacta tctatttgag ttggatattt tgtaacactt
     1561 tcttttttta tatagcctcc gaaattagaa ctctctctcg ccagcctgct gttctcaagg
     1621 ttcttcaaaa gctgctggtg attgtaggtc ggtttcgtca ctctagctgc tattggctca
     1681 ttcaagctga accttctggc ggcacttgag gcggcatagc ctgctaggat attccctacc
     1741 aaggtagctc tttgggcatc ttgctcactg ccgcctaaga gcttggtgcc atgatagctg
     1801 gcctgaccac cgataaagcc gccaacctca ccgatcgtaa actctgtcaa gcccttggca
     1861 acactcttgg tctgaccaat cagaattagt gctgcactgg ctgttgtgaa cagcccgccg
     1921 atctggtgat aaagcctgtc attccccatg aacaaggtat cccgaagggg attggtagcc
     1981 actgtaagcc catcgccaac gctacctaga taaatgttgt gcccagcctc atacaggttc
     2041 gacgccccat aagcaactgt accactgcca acaacaaagg ccccaaccac caagggagtc
     2101 gctgcccctg ctgtcatgac gatagccgca accccaaccg ctattgtcac aaggctgagt
     2161 gctagatcta tccagccctg cttggccctg tcctctgcag ctactgcctc aaaacgggca
     2221 tgatcccgct cctgcgctgc ttggagacgc ttggcattgg tctcaagatg acgagccacc
     2281 ccctgataag ctgtcgcaaa gcgttttatg gtgttgagct gtcctatatc cccaacctga
     2341 tagctcccag cccgcttggg cttactgctg tactctgcta tcaaggcctt ggtcgaagcc
     2401 aaaagctcct tgaaggcggc caagtcctga ctggcatgat tgctttcgta ttgaatgatg
     2461 gcctcgtcca agcgatggat atcagtgatc agctcactat aatccactac tgtcttggca
     2521 tgactgacac cagagtagtg aaccaggtct gataacttag ctctggtatt ctgtagtagc
     2581 tcaagctgat ccttgaggtg ggcctgcgag agccgaagct ctgactgcag ggtcttaaag
     2641 acctgaccgg gtaactgggc atgactatta ctgtctatct ggtaatagcc gtccttatac
     2701 agcaagaggc tagctgagta atcattcatc aggctttgca gggtttgtaa aagtgtccca
     2761 tgcacctcac tcagatagct cttgattgag ctagcggtct gaccctgaag gcgactgtct
     2821 ccaatcaagg ctgacagggc ggtctggata ctcgttatcc catctcccca agcactgatc
     2881 gtggtttggg tgctttgttg aagggaggta atctcatcat atttgatatt atagctcatt
     2941 tcttccccta acgttttcaa tgcgatatca aaatgtttca ccaataatag caatacattt
     3001 ctttaatata cctcttttat tatatcaaaa aaaacttaat gattatcaca ccaagctaag
     3061 agcattgatg ggtaataaca tatagcttat ccaaccttgt tagcaggagt attacaaata
     3121 atgtattgcc aagaggaaaa gctgatataa ataggtggga caaacgtggt caagaaaacc
     3181 tttaacacca agaaaaccat gataattctt gataacatca aatagtgcct cagctaaatg
     3241 attatgatga cctttaccaa atcattcttt attatctgca agaaaagaac agtgacatct
     3301 cttcgatccg attacgaata taaatcaagc ttcaaaaccg ctcttagtac ctttattcgt
     3361 tgccaaaaat atctcattga actctcttat tcaaacgcta agctagaagc aaccaataaa
     3421 ctgagcaaaa acataaagcg gcaagctttg gctttaggaa cttcaaagct aagattccca
     3481 atacttttaa catcacaaaa gagagcacca agctggtcct ctctagatat tagttattag
     3541 tcaccccact acagttgaca ttgagcctct ttgatgacac tagtcgtgaa ttagtgagac
     3601 aacaacatag cgattagggt cgttgccctc tgaatagctc tcaaccccat caatagcaga
     3661 aactgtttta tgaacaatct ttcgctcgct gttactcata ggatccatgg tataatcttg
     3721 accagactca agcacacgct tggatacctt tttggtaaag tcaatcaggg tttctgtccg
     3781 atgctctaca taatcatgaa cattcaagga gacagaaaaa ttcttagaat agcggtcatg
     3841 taagaaattt tgggccagca attgcagtga tttcaaaacc ttaccatgat agccaataac
     3901 acgacctgcc tctggtgtct ctatctgaag attgatctga cgacgattgt tggtcctctc
     3961 aatagaggct tcaatatcca tctcatagat aatcttggtc acatagtcag aaatctcctg
     4021 tgcagctagc tcaatatcct tactcatgtc cgctgcagct ggatccagct gactcgcacc
     4081 agcagctgac gacacaggct gtgcctttga ctgagtagga gctgactgag ctgtgcttaa
     4141 tggacctgtt ggctgatgag catcagactc agcagccctt ctgtcttgtg atcgaacagc
     4201 cttcatctcc tcaagctcca cctcatcggg gttaataacc ggtgcatttt gacggttgat
     4261 ctcctctgga acactacgta cggctttttt atcagcctta tagactgttt tttcattaat
     4321 gccttcaata tcaacctgag ctggcttttt accaaagccc aaaaagccct ttttctcctt
     4381 tgaaatcacc ttgatgtgtg cttttagacg tgacaacccc aactcttgaa gtcctttttc
     4441 aattgcttct tcaacagtct tacctgtaaa caataccata tcctaaactc ctattttctt
     4501 ttcattgctc tcttacgagc gcgacgttcc ttagctcgac gctctttttc ttcatctgct
     4561 aaacgttgcc tttcggcaat aaccttaaag ggattattaa acagcaagag ctgaacaacc
     4621 tgaaaggcat tggaaactgc ccaataaagc accacaccac tggccagatt aaagcccata
     4681 aagaagatga acacaggcat cacgtaggtc atgatcgtta tcatggccgt cttttctcta
     4741 gccgctagat tggttagcca tgttgataaa aaggtaaaga cagccgctaa aataggcaga
     4801 ataaagagat gatcatgtcg cgccagctca acccataaaa aggtgccttc tcttaagaaa
     4861 gccacacgag tcagagactg aaacaaggca aacatcaccg gcatctgaat cagcaagggc
     4921 aaaaggctca tgtaaggatt gacaccatac tttttgtaca gagcttgact ttcttcagct
     4981 agcttcatac gagttgctgt gtctttagca gcatattttt tttgcagggc ctttagctct
     5041 ggttgaatgt cctgcatttt ctgccctgac ttgatttgca tgttaaacaa tggcagtaaa
     5101 agcaagcgaa tcattatcgt aaataggata atcccaatcc cagtcgatcc atcaaaggac
     5161 aaccattgga tcgccttggc aaaaaaataa accaattgct cccagctact agatgattgt
     5221 gctgtcacct ctccacgccc acaggctact agtagcaaga caagcggcac tagggctgct
     5281 gttttaactc tttttttcaa tctcaaaacc ttcctcaagc aattttgcta gctttaaaac
     5341 atgatgtaaa ttttgtttga ctgcttgata atctaattcc tctgcacctc tcctagcaat
     5401 aacaacgaaa tcctcagact tgaggtgatc acccagctcc attaaaacat gtcgtatctt
     5461 gcgctttacc gcatttcgag taacagcatt tcctagcttt ttgccaacag aaatccctgc
     5521 tcgaaaatgc ttgtgctccc ctttcaaatg gtaaatgaca aattttcgat ttgccatgct
     5581 ctgaccaagc ttaaaaatcg cctggaaatc tttctctcgc ttgacacgat agcttttctt
     5641 caaaacttaa ctcccatatc taaattatta ccattatacc ataaaacatt aaaaagcctc
     5701 aacccttatc aatgggccta taataagaga ttggacccac tatctaaagg atcagaacaa
     5761 aaaatgcttt tagtgaatca cggtagctgt caagtcttga tagccttatc aatcatacta
     5821 gcaaagaaac aaaaaaataa agcccggtaa accgagcttt atctccgctg acttgagcat
     5881 cagcaaatat gatatccaaa caaagacaac tgaaacaatc attttaataa caagcagcca
     5941 tatcaaaaat actatttgtt tatggagaga gagagaaaac aatattttga ttgaattggg
     6001 gatggaccac tccattacct aatgatttcg taaatcttta ttcatactag acattatagc
     6061 gaaaaatcac taaaaaagat gacaatttcc tgaaatgttc atttttcgtc ctaaaatgtc
     6121 attcaactta atttttagcg aaaagacttc cacttttcaa aaagctgttt cattctcaaa
     6181 cgagagacca tacaagaatc accattttca aaatacacca attgcttagc cttatcaatt
     6241 cgaacaacat tgtcaagatt gaccaagtaa gaacggtggc ataaaaacag cttaggagct
     6301 accgcatgaa tctcagataa gttcccataa aattctaagc gctctgtttg cgtccacagg
     6361 cacaccttgt gaggcgttgt tgcagttgca aaataaagaa tgtccttata aggcagcttt
     6421 aggcgggtct gcggggtctc aaacaaaaac atctcttcta cttgacgact cgacatcatc
     6481 tcataggtgt agcgaataca ttcctcaatg cgctctttaa attgctgact atcaaccgct
     6541 ttatcaataa aatccaaggc agacaccttg tacctaaagg aaataggggc gaactctgaa
     6601 tgcgtcgtga caaaaacaag cacagcattg ggatccttct ggcgaatatc tgaggctagc
     6661 tctagcccac ttcttgattt gtcaccaatt tcaatatcta aaaaatacag ctgatgatct
     6721 cctctctcct gaatgctatc aaacagcttt tgaggatttg aaaacacctc taattgatta
     6781 tgaggaatcc taccctcttc taatatggac gccacaatgg cctcaatacg actttgttga
     6841 atcagattgt cttccagaat aaaaatgttt agcatggctt atctcatttc taacaattgt
     6901 ctcaaacggt agtgatcact tttggttgaa aaggtgatgt ggggatagcg ctctaacaca
     6961 gccgagaact gtagcaggcg cttatgagca tggcttccta gctccaatcg gctagcatca
     7021 aattgcttgg caatatcaac ccgcttgagc cttgtactat tttcaatgat aaaaaatcgc
     7081 ttgccatctt gattaaaata ggcaatggat aaaaaaggac gagagctgcc tttagctgac
     7141 aaaatagcat tatcaataac taccttgaaa agaacgatga catctaacag cctgacagaa
     7201 gagctagcaa gcgtttcagg aatatcgatg taaacagcaa tgccctgcag ctttgcttct
     7261 aatagcttgg catgcaatag gctgcgaatc accgaatcct gaacattatc aagggctgat
     7321 aattcaggtg ttagctgcct gatagagctt gctgattctt ggataactgt ttgatagacc
     7381 ttagaaatag cagctatatc tccactatca atactatcct ttagactaat tagaatattt
     7441 tctgaatcat gcttaatagc cctgatctca cgacaaagcc gctcaatata ctgattgtgc
     7501 ttttcaaggt aagcaacacg ctccttttgt gccagagcca atctttgaga tagctgatcc
     7561 ttagcaaagc ggtccagctt gacaatgacc cagatgagca gcatgaggta aagaaaaatc
     7621 atgacagagc ggtaacgaaa ataaatcttg aaaaaatctc cttggatatt gatcatgcag
     7681 tgaaccatca catagtagaa aagtaaggct gcattcatcc aaaagaccca cttctttagc
     7741 ttgtcctcac tgataaactt aatcaaggtc aaatcaacgc taaaaatata gctaaacagg
     7801 taaaaggccg gcaaaaccaa tgcatgacag accatcaata gacctatgtc attattgatt
     7861 tgatgaatgc tgtagcctaa aaccgctggc aaaaggaaag agccaataat acgaaagagc
     7921 agctcaacaa tcataatcgc aaacaagcca ttaaacagat gctcagaagc ctttttatga
     7981 ggtgcaaagc caacactgac agcaacaaac accagctgat caactagcag cacatgatcc
     8041 agcagcagat tagcaacaac aaagcaggca ccaaccaaaa gcaatgatct aacagctagc
     8101 ttaatgcctg aaaatgtcga aaagatgacc cagctattca caaagatcag agcataaaag
     8161 aatgacatac ctagcataaa ataaaactct actctttctc tatttttggc atgattaggg
     8221 tctgactaaa ctgataatca tgactcctgg tgcgcaagga tagctcagga tatttctgca
     8281 aaatccgctt ggcattagac aagcctatcc ctcgaccgct cccctttgag gaatagccct
     8341 cttcaaaaat cctactaatc atgacccttt cgtccttggt cgtattggtt acggtgaaaa
     8401 tctgctgatc atcagataaa aagtaggcta tcgccactgc tggctgggct gtctctagag
     8461 cagcctcaat agcattgtca caaaaaatag atacaagcag caataaatca agctctgaga
     8521 tatagctatc ccgaatccga tctggaactt ctaggcttaa ggcgattcct gccttctcag
     8581 ccttaatgat ttttgatgat agcaagcttt ttatcgagga tacactgatt ttactgagct
     8641 ttgaaatatt gtaatgctta tcgtcccaat aatccgtcgc ctcatctacc gtttgggcat
     8701 agacagtctg tacatctgac acagagccag agtcaatagc ctgccccagc ctttctagcc
     8761 tcttgaggta aactagctga aataccttaa cacccttata aagcttttct agatgctttc
     8821 cataggtttc cagattagca atataagcct gctgttcctt ttttaattcc tgttttaaga
     8881 attcctttga ttgatgatta aaataagaca gtaaataaat caacaatagg gtaaagatga
     8941 gaaacagcac cttataagac gttgacatca ttatcgggga tttaaggtca agaaagggat
     9001 cagtaaatcc taaaatcata aagagatcaa tatagtaggc caaactaaag agcaaaaaca
     9061 agctataaaa gctactggcc ttatcaaacc tgtcagcttt aacaatctgc ttgtaatcct
     9121 ttcccacaaa ataattaatc aaagcaaagc ttgggaaaat catcacataa gcaataaagt
     9181 ctaggacaag gtgtctgaca tagctgccat taactgaaaa aatataggga agtacaatcg
     9241 ctaaaataaa gcgtgataac aaatcaacaa acactccggg aacaaaggcc aagaatagag
     9301 cctttaagct aaagcagggc cgcttttcta aggctaatac agctagcagc aataaaggat
     9361 caattatcaa gggcggcaat aaagcaaact gattcaaaaa gagagctgct gtcaggacaa
     9421 aaatctgctt ccaaagtgcc agtttaatgt ctgataaaaa ggaaaaaata ctaatttctg
     9481 tcacataata aatcatcagt gatagtaata aaaagagata ataaatatca gtcattctgc
     9541 ctccttacca actttattat tttaacacac tttgtgtcaa tccctattat atgaattttt
     9601 tatataattc agcaagcgca aaaacagtcc atagctggtt tgtgacagcg tttgcaaatc
     9661 agatgtcaat cattaaagca aattaaaata tctgaccagc cttaccttat ctagggaaaa
     9721 atattgtata acaaataatc taagaaaacc agtgacaatt taatatttat tttaataata
     9781 tcttccacgc tcatcaaaaa ttaagcagat aagcctgctg gattatgaca tctagctatg
     9841 cgctactggg cgtcgtgtcg ctagctcaag cacactaaaa aagaatgaag caaacatcag
     9901 atatctcatc tctgcttcat tcatgatgtt atttatgatc atcgtccagc ctagaccaaa
     9961 ctactagctg cgatagtgtt taaagcatat tggcaatatg ctcaatcgat tgttcacgtc
    10021 caaggaggta aatggtattt ggcagctctg ggccatgcat ttctccagaa acagcaatac
    10081 gaattggcat aaagaggttc ttgcccttaa tgccggtttc tttttggaca gccttgattt
    10141 gtgggaaaat gttttctggc ttaaagtcct catctgacat cgcctctagc ttttccttga
    10201 aggccttcag aactgttgga acagtctcag ctgccatcac ttctttttct tttgcggtca
    10261 gctctgggaa atctgagaaa aataaatcag tcaatggaac aatctcatca gcagagctta
    10321 attgaggctg atagagctca actagcttct ctgctttttc agtcaagcgg cctgctgctt
    10381 caagaaatgg cttacaaagc gcatatacag cgccaagatc agcatgctta aagtactcat
    10441 tgctcatcca gtccattttt ttctgatcaa aggctgctgg cgacttgcta agacgaatct
    10501 catcaaataa ggcaatcaat tgctcacgag aaaagatctc agcctccccg ccaggattcc
    10561 agcctaaaag ggcaataaaa ttaaagactg cctctggcat atagcctttt ttgcggtaat
    10621 cctcaataaa ctgcagggta ttggtatcac gctttgatag ctttttacct gtctcagaat
    10681 taatgataag ggtcatatga ccaaagacgg gtgcttccca gccaagcgcc tcgtaaacca
    10741 tcaactgctt tggcgtattg gcaatatggt catctccgcg gataacgtgt gagatttgca
    10801 tatcgtgatc atcaataaca acagcaaaat tgtaggttgg atagccgtct tttttctgga
    10861 ttacccagtc accaccgaca ttgccaccct caaatacgat atcgcctttt accatgtctg
    10921 tccatttgta aacaccagcc tcattgaccg ctaaacgaac cgtaggcaca atacctgctg
    10981 cttcacgctc tgcaatatag gccgcctttt catatgctga catgccaagg tattcattga
    11041 catagcgagg tgtttcacca gctgcctctt gacgctcacg ctctgctgcc agctcctcct
    11101 cagtcacata agacttgtaa gccttgcctt ctgccaataa ttggtcaatg tattgttgat
    11161 aaagggctag acgctctgac tgacgataac gctcgtgcgt ctcaggactt tcgtcccaat
    11221 ctataccaag ccattttaaa ttttccagct gagaacgctc gccgtcctcg acatgacgct
    11281 tacgatcagt atcttcaata cgaataataa agtcaccgcc atgatgacga gcataaagat
    11341 agttaaagag cgctgtccgc gcatttccga tatgtaaaag gcctgttggg cttggtgcat
    11401 agcgcacacg aattggttta gacattcttt ttctcctatg gtttcattga aagaagggat
    11461 cctgggctat aaaccgttcc tacggtaggc ttgctctatg agaaaatggt cgataaggaa
    11521 caaaaataca gctaatccct tggaaatcta aagatttcaa tcgctcctat tatagcacaa
    11581 cttcaagcat tgggcgacaa aaatcaactt agaacagctg cataacgaaa atgcatgtaa
    11641 ccattttcta gctacatgca ttgttttcat ctacttctga tattttgata tcatcagctg
    11701 ttcacattca gcttaattgt agcctgaatt gatttgaaaa agaccatacc actgatgaga
    11761 aaatcgctat caaaaacgta aagatcctta tgcgtttggc gtggcctaga gctaggatag
    11821 ctctataagc agctcattgg caagcagtgc tgcctctttc aatagcttca tagcatgcct
    11881 agctatagat attagtcagg ctattgacct gcattgatgt caagctacac cccagcaaag
    11941 aaagcgacaa tatactctgg caaccacgaa cctgtcatat ccatttcaat ccatcaattg
    12001 gcaaggcttg gtttacttcc aactgcttaa tggccgcctg tgacaatata gctctgtaaa
    12061 actccagcaa attgctgaag gttcaggctt tgcacataga catctccgta tccgctaaag
    12121 gtattgacca ctccctcacc tgtaccaata gactgcataa agccattttc caaatgaata
    12181 tcataatcca aatcctgact ccaagccacc acatggctat tatcaatcgt catgctgtcg
    12241 ccatgaagcg tgattttttt aatcgaacca aaagcattga ccaatagggt tccttctcct
    12301 tgtgttgaca tcacaaagaa gccaccctga ccgctaaata aggccttacc aagtttttgg
    12361 cgcttcatgg tgtagtgagc tgagccatct aaagccaaga aggctccgtc attcaaacgg
    12421 tattgatcta cccctagctc aagagcaata acctgaccag gcattgaagg ggcaagcgct
    12481 agcttgccac taacatcatt agcaatcgcc tgtgtgataa acatggattc tcctgaaacc
    12541 attgaacggc caatggcacc aaccagcttg ccaagacctg agccacgccc attgagcttg
    12601 gtgtttaagc tgattgacgg tgtgtggtaa accatactgc ctttttgtag aaagacagac
    12661 tcccccatgt ccaaatcaat ttcaacaaga ggaaactgca tgctgctgtc aatagtatag
    12721 gtcattcgat tataggccat aacaccactc ctttgtatga ttttgttgat acaatcaagt
    12781 atagtctttt ttggcagcat tgtccactag ctactgtcgc cgccattcct aaccagtctc
    12841 aaagccatac tacaaaccga tcagctgtca ggatttcggc atcgccacct gagacatacg
    12901 tccagtggca acatcataga ccgcaccact aatgaccacg tcttttggaa tcaacggtga
    12961 ttgctgcaat atagccatat cctcacgaac acttgcttcc acatcagtaa aggggagaaa
    13021 atcacagtca gacacatcta ctcccagagt atcatgaagc tgcgctgtaa aggcttcatt
    13081 ggtaaaggtt tgcgccccac aatccgtatg atgaagaaca acgatctcac gcgttcccag
    13141 ctgctgctgc gaaatcacaa gagaccgaag catgtcatct gttatccgtc caccagcatt
    13201 gcgtaaaata tgggcatcac caagcgctaa acccaaggcc tgcgccacat gcagtcttga
    13261 gtccatacag gtcacaatag ctaccttagt tttgggcttt aggggcaaat gagcagtccc
    13321 atgtaaggcg acataggctt cattggcaga taaaaagcgt tcaaaatatg acatgaatac
    13381 ggtcctccca gactaatctc taagctatct cagccttgag ctgtctgtct atcttatcat
    13441 cttttgcctg aaatgtctga atgctgaact gctttttaac acaagcagat agcactagcc
    13501 taactgaaac cagaggtagg tgagccagcc ttgacattgg aagcaagctt agcagcccgc
    13561 cctttgagcc gctaaagtaa gggcagcaag aacgtgacaa aatcagttaa ttgtcatttt
    13621 aattaaaaaa cgaaactacg gagacaaact gataaattgc tatttctcgc tatcagccag
    13681 tatgctaaac tcttctcaga aggccttggc agtcgctagc tgctaagcca ataatactaa
    13741 attaaggaga atagcaatga aacaaacaaa aataatctgc ttattggctg ctgctgctgt
    13801 cctaacccta ggtcctatca gcacaggcca gacacaacca cagaccgtat atgccagtca
    13861 ggttagtgga gacagctgta tcgatctagg taatggatgg tttaaatgtc ctaaggatat
    13921 tggaggatgg gacattcttt ttaatcaaga ttaccaagcg ccttcacgat cgccattttt
    13981 cacttggatt tcaggctggt ttaactttat atggcagtgg tttaaaagct tctaagatct
    14041 actaatacgc tatccatatc ataaggctct tagaggctag ctctctaagg gctttttggt
    14101 tctacggaac actataagga ccttccaata ctactggtct taaaataaaa aagactagga
    14161 atagctcccc tagtcctcat gttaaaaaca acaacctaag taaagacagc ctttaagacc
    14221 tctcctactg tcgtcacacc aacaacctca atcccttttg gcagatcaat cccctgcaat
    14281 gagcttttcg gagcgtaaag cttggtaaag ccaagcttag cggcttcatt aatccgctgc
    14341 tcaatacggg tcacacgccg aatatcacca gtcaagccaa tctctcctaa aaaggcctcc
    14401 tgagggttgg ttggtttttc cttgtagcta gaggcaatgg ccacagcaac tgccaagtca
    14461 atagcaggct catctagctt cacaccgcct gctgacttga ggtaggcatc ttgattttgt
    14521 agcagcagcc cacatcgctt ttccaagaca gccataatca gactgacgcg attaaagtcc
    14581 aacccagttg tcgttcgtct agcattacca aaaacagtcg gtgtcaccaa ggcctgcacc
    14641 tcagctaaaa tcggtctgct cccctccatg gtgacaacca cagcagagcc tgttgcgccg
    14701 tctaatcgtt cctctaagaa cacctgactg ggattgagga cctccactag cccacctgat
    14761 tgcatgtcaa aaataccaat ctcattggtt gagccaaaac gatttttaac cgctcgcaag
    14821 atacgaaagg tatgatgcct ctcaccctca aaataaagga ccgtatcaac catatgctcc
    14881 agcatgcgag gccctgctag ggtgccctcc ttggtgacat gtcctacaat aaaggttgca
    14941 atatgattag acttagctag ctggagcagc tcagcagtga cctctcgaac ctgactgacc
    15001 gagccctgaa cacccgaaat ctccggactc atgatcgtct gaatagaatc aataatcaaa
    15061 aaatccggct gaatggcttc aatctctgct cgaatagcct gcatattggt ctccgcatag
    15121 aggtaaaaat cattgtcggt ctgtcccaaa cgatcactgc gcatcttgat ctgctctgcc
    15181 gattcctctc cagagacata taaaacagtt cccttatccg caagctggat agaaacctgc
    15241 aagagcagcg ttgacttacc aataccagga tcaccaccaa tcaaaaccaa gctccccggc
    15301 acaacaccac cgcccagcac acgattgaac tcattcatct ctgtctggat acgctggtag
    15361 cgaacgccat tgatatgctt tagcttgatg ggcttacttt tttctccagt caggctaata
    15421 cgggcatttt tgacgtcctt gacctctgtc tcctctacaa aggaagacca ggcagagcaa
    15481 ttagggcagc gccccagata tttgggtgac tgatagccac attctccaca gataaacctc
    15541 gcctttttct tagctataac acatttcctc cttgaatcta agcatcaact ggctacaagc
    15601 acgtgaagca gcctgctaat accttatcct cctgtcgaac caaaaccacc tgtccgctca
    15661 ccaccagcct gatcaccatc agcaatcaaa aaaggcataa atacgccctg aacaatgcgc
    15721 tcaccagctg acaaggtaat ggtttgatcc gtaatatttt tcatctgagc aaaaatatgc
    15781 ccttcattcg cagggttacc atagtagtca ccatcaataa cacccacaga attgatcaga
    15841 accagtccct ttttacgagg attgctggag cgatcataga gataaagcac ctcaccgtct
    15901 tgcatatacg ccttgacccc tgttggcaca agtacaatct cacctggtgc aatgctggtc
    15961 tcctctgcaa cagataagtc atagcctgct gcatgagctg tctcacgttt tggtaataaa
    16021 tcagtatcag taaagcctga cacaagctca aagcctcgaa tccttgtcat gattaacctc
    16081 aagagccctt gtcagtgcct gcagcagctg taaaatcacc tgccaggaca gcagacaaaa
    16141 gcactcttat cccttttctt tttttagtcc tcttattata aaatattcgt aaaggaatag
    16201 caaaaaagta ggggctgcac cccaaaaatc accgactgcc cccctctata acgcaacaaa
    16261 atgcaagagg gctaaatctc cttgccggca tagctaaacc gaatccttgg aaaatcagcc
    16321 tccaaatcct tatctgccat aaaagccttg gcgtcctttt tcacctgaac cagatcaatc
    16381 ccttgtatgt ttgcagcata gacgcagccg caatagcact ggcggtaaat atcatattcc
    16441 tcacacattt cgaccgacct gcgatagcca ttatttttct tgaaatcact aggcaaatac
    16501 ttagtggtgt aaaccttttg cacatcaatg cctacatcgt taatcgtctg tgagttttta
    16561 tgagggctga tggtcaaggc actagcaaaa taatcaaagc ccagctccac agccttttgt
    16621 gccgtcttgt ccaagcgata atcaaagcaa acacgacaac gatccccgcc ctcagactct
    16681 ttctccaagc ctcggacagt cttgacaaat tcatttggca cataatctgc ctcgataaac
    16741 tgcacgctat tacctgtttt atcgttgaac tctgctacaa atttctgagt aacataggcc
    16801 ctgcggtggt attcgtcctt tgggtgaata tttgaattag caaaataaac cgtaatatca
    16861 gcgtactggg ttaaatattc cagcgtgtag gttgagcagg gagcacagca aacatgcatc
    16921 aaaatgcgag gacgtataga ctccctcgcc cagaccttgg tcatctgctg catgacccga
    16981 tcatagttta ttttctggtt tggattcatt ctagctagaa tctcttgtaa gtcaatcatt
    17041 acatcttcta ccttctattg tctgtctctt ttattatagc acattgcctt gacatgcttt
    17101 gcatcaaaaa actccgccaa agcggagtcg atcggcaaaa gctgttttga tggtttttaa
    17161 gaataacaac agcagcttat gtaatgatca tttttagaag ctactcaaac acaaactgat
    17221 tgtgataaag ctcggcataa aagccctttt gccttagcag ctcatggtga cttccctgct
    17281 caataacctt accgtccttt agaacgatga tttcatcagc atttaaaatg gtttttaggc
    17341 ggtgggcaat cacgaagctt gtgcgacctg ccacgatagc ctccatagcc ttttgaatct
    17401 tactttcagt aacagtatca acatttgatg ttgcctcgtc caaaatcaag acctgaggat
    17461 cggttaacag cgtacgagca attgaaataa gctgcttttg accagttgaa aagacattct
    17521 catcatctga cacctgagtt tggtagccat caggcaagga catgataaac tcatgaatat
    17581 gcgttgcacg cgctgctgtc tcaacctctt tttggctgat tgtctgatta ccaaagcgga
    17641 tattatcagc aatagtccca gaaaacaaga ctgactcctg taggacaata ccaacccgct
    17701 gacgcagact atccaagtca tattccctaa tatcacgacc atcaaaggta atagagccag
    17761 catcaacatc ataaaaacga ttaatcagat tcatgatcgt ggtcttgcca gaccctgtcg
    17821 gtccaacaac agcaaccatt ttcccctttg aagctgaaat cgacacatct gacagaattt
    17881 tttgtcccgg cagataacca aagtcaacat gcttaatctc aaccccttct tttaatgctg
    17941 taaagacagg agcatgctca gggcgaacct cttctttttc atcgaacatt tcttggatac
    18001 gaccagcacc tgtaaaggcc agctgcaatt caccccagct agaggcaatc tgcataatcg
    18061 gttgataata ctgctgtgaa tactgaacaa aggtcaccac caagccaaga gcagcagctg
    18121 ttgacatgga cttgtcacca aggacaatgg ttgagccagc aaagatgaca atagctgtat
    18181 tcaaaagact catcccattc atcacaggaa acagcagacc agcaaaaagg cgtcccttaa
    18241 aggttgctgc acgcaccctc tcattgtgct caataaagcc atcaatagca tcctgttgca
    18301 ccccttgaac aataatagcc ttctggccag aaatcttctc gtccatgtaa gcatttaaag
    18361 cactgacctc cttttgctgc aaatcagtat atttgcgggc cattgtaatg atgacaacga
    18421 gaagaataag cgccacaggg gttgaggcta tcgttaccaa ggccaagcga ctatcctgcc
    18481 taaacatcat cagcactaga ccaatataca aagcaatatt tgtcaagacc tgaatcagag
    18541 attggttcat ggagttttga atattatcaa gatcactggt aaagcgtgat agaatagcac
    18601 cgtccttgtg actatcaaaa aagccaactg tcaagcgctc caatttgcca aataagccct
    18661 tacgcatgcg attggtcgaa tgcgaaataa cccttgtaaa gaggagacta taaataagat
    18721 tagccactgc tgtaaagaga taagccaaca atagctttcc cataaccgtc ctaaaaggcg
    18781 ccatagaggg ctcaactaag ggctgacccg tcattttgct aagcgcctga gccttgtaat
    18841 agcgctgcac ccattctccc agctcagcta gagagtctcc caaaaagaca ggggccttaa
    18901 cctgcaggta ggttgccagg acaatagcaa agaatatcac aacaaaagag agcttataac
    18961 gtttaaaata aaaccagaaa aatcgcagga tcttcattag ttctcctctc ttcccttttg
    19021 agtttcgtaa atttcacgat aaatcggatt ggaagcaacc agctcagcat gcgtcccttc
    19081 tccaatcaat cgaccattat caagaacaag aatcttatct gccttgacaa ctgacgatat
    19141 tttttgtgcg atgatgactg ttgttgtctc tttgagctcc ttattcaagg cctcctgaac
    19201 aagcttttca gatttggcat ctagagctga tgtcgaatca tcaagcacca aaatcttagg
    19261 attgttaatc acaccacgag caattgacat tctctgcttt tgaccgccag aaaaattatt
    19321 gccacgctct tctacctcac tctggtagcc agcgtccata cggtcgataa attccttggc
    19381 ctgcgcaatg cgtgctgcat tttctaaagc caattggtca gcatagggat tgccctgacg
    19441 cagattatcc gcaatagtcc cagaaaaaag aatagccttt tgcagcacaa tagagacggt
    19501 gtcgcgcaga gtctcttgac tgatgcttgg cagagcctta ccaccaatca ggatttgccc
    19561 ttcctgtggg tcaaacaaac gcggaatcag ctgcgcaagg gtcgacttgc cagcacctgt
    19621 cgcaccgaca ataccaacca tttgaccggg ctcaacctca aacgaaatat gctttagagt
    19681 ggcttcactg tcatttggat aggtaaagct cacatcatca aagacaatac tgcctgtcag
    19741 ctcctcctgc tcatggttaa caaaggtcat agcaggctct gtttctaaaa tctccctgat
    19801 ccgaccaatc gaggtcaagg cacgacttgc ctgcattccc ataaaaccaa ccatcgtgat
    19861 cgcaaagctg atttgtccca tataggtcat aaaggaagcc atatttccaa taacagcagg
    19921 atctgttttg accagccctg aaaccagata caaggacaaa taaatggcca tgtaagacac
    19981 caacatcaaa ataggctgca tgattgaaaa gccatagccg ataaacaaat tcaagcccag
    20041 taggtcattt gaagcctcct taaatgtgtc atactggctt ttttcctgaa caaaggactt
    20101 gaccacacgc acaccgcgta ggttttcctt agcaatctga ttgatcctat ccatcaagcg
    20161 ctggaagatc ccaaagcgag gacccatctg gctcatcacc agcccaatga ctaccattgt
    20221 catcacaacc acaagcacca agacccacca aaggctcggt aaggcctgca ccgctaaaat
    20281 aaaggcaccg acaaataaaa tcggcaagcg caacaatatc tgaaaaagca tcatcacaaa
    20341 gttttggatt tgattaatat catttgtcat tctaacgaca agatttccag cattgaaggc
    20401 ttccacattg gcataagaaa aggattggat ctttctaaag gtctgctcac gaatatcagc
    20461 agatacccct tgagcaatct tggcagacaa gatggtattg accgcacctg acaccaagcc
    20521 aatccctgct atcactaaca gccaaaaacc cacctctgca atccttgtct gatcattttc
    20581 cataatagca gctagaacat ctttgaggta atgtggctgg agcagggcac tggctacgac
    20641 cccagaaatc atcactaggg acagagccgc ataccattta tacttcatca cagcatttct
    20701 aagcatctgt atctccttta taagctcgta tattttgttt cagctgatcg ataacctttt
    20761 ttaccgtcag cagctcttct cttgaaattt ccttgaaaaa atagcgctca atatctctgc
    20821 ggcactcctt taataccggc agcttagccc taccagccga ggtcaagaca acctgcttgc
    20881 agcgcttatc tgtagccgag gcaacaactc gaataaagcc atttttttcc atacgcttca
    20941 ccagattact cgtaaccgat tttgagattt gaagctcctt ttcaatgtcc ttgacaaaaa
    21001 tgtctctgtc ttgatggcaa tgcaaaaaga caagaacatg cccttgtgga ccagcaagat
    21061 gctggaggtc atacttttta gcaatctctt cgctaatttg ctcaacctga tgggtcaatt
    21121 cacgaagctc agcaatgatt cttggcattt ccttcctcct tagttctcat gataaccatt
    21181 ttagttctct tgggaactat tgtcaaccaa aaaggcttac gatctgacta tcttccctgc
    21241 tacttaccct ttgctagcac cactgagctg acaggctagg ccagcagacc ttttctatta
    21301 gagttaggcc ttgtcttatg atataataag gtgattagct cttaaaggag aataaaaatg
    21361 ccaaaacaaa aggtagccat tttgggacct ggctcttggg gcacagccct ggcacaggtc
    21421 ctaaatgaca acggacatga ggtccgacta tggggaaata tccctgaaca aatcaacgaa
    21481 atcaacacac gccatactaa tagtcattat tttaaggaca ttgtcctaga tgaagccatc
    21541 aaggcaaccc ttgatttgaa ggaagcattg gctgatattg atgctatatt gtttgttgtg
    21601 cctaccaagg tgactcggct tgttgccaag caggtcgctc aggtcctaga ccacaaggct
    21661 attgtcatgc acgcctcaaa gggattagag cctggaaccc atgagcgcct ctcaacgatc
    21721 ctcgaagagg agatccctgc ccagctgcgc agtgaggtcg tggttgtgtc tgggcctagc
    21781 catgccgagg agaccatcgt tcgtgacatt accctaatca ctgcagcctc aaaggacatc
    21841 acagctgcta ggtatgttca gaccctcttt agcaaccact acttccgtct ctacaccaat
    21901 actgatgtga tcggtgttga aaccgctggc gctctcaaga acatcattgc tgttggagcc
    21961 ggtgctctgc atggccttgg ctatggtgac aatgccaagg ctgctgtcat cacacgcggt
    22021 cttgcggaaa tcacacgact aggggtcaag cttggggcag accctctgac ctatagcggc
    22081 ctatctggtg ttggtgattt gattgtcaca ggaacatctg tgcattcacg caactggcga
    22141 gctggtgctg ctcttggtcg cggcgaaaag ctcaaggaca tcgaaaacaa tatgggcatg
    22201 gtgattgaag gcatttccac aaccaaggta gcctacgaaa ttgcccaaga gctaggggtt
    22261 tatatgccaa ttaccagcgc gatttacaaa tctatctatg aaggtgctga cattaaagaa
    22321 agcattctgg gcatgatgtc aaatgaattt cgctcagaaa atgaatggca cacataagga
    22381 accacaaatc aaggaggaac tcatgacaaa ggtcagaaaa gccattatcc ca
//
LOCUS       DARYXW010000026        22105 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.026, whole genome shotgun sequence.
ACCESSION   DARYXW010000026 DARYXW010000000
VERSION     DARYXW010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22105)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22105)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22105
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.026"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            449..1933
                     /locus_tag="TV191_000805"
     CDS             449..1933
                     /locus_tag="TV191_000805"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004229889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEL1507338.1"
                     /translation="MPMMYQSTRNAANKVTASQAILSGLADDGGLFTPTSMPVLDLDF
                     EELKTKSYQEVAKLILSAFFDDYTEAELDACISSAYDDKFDTAVIAPLATLKDYHNLE
                     LFHGSTIAFKDMALSILPYLLTTAAKKQGVERKIAILTATSGDTGKAAMAGFVDVPGT
                     DIIVFYPKSGVSRIQELQMITQAGHNTHVVAIEGNFDDAQTEVKRLFNDPDLRERLAA
                     QQIQLSSANSMNIGRLIPQVVYYIYAYAQLVRHQRLEAGETINIVVPTGNFGNLLVAY
                     YAKEIGLPVAKFICASNENNVLTDFFASGRYDKKRPFKVTTSPSMDILVSSNLERLVF
                     YLLGNDAQKTAVLMKSLAETGQYQLADADQSILDLFAAGFATEQETAKEIKTIFESDH
                     YVLDPHTAVASAVYRAYREQSGDSRPTIVASTASPYKFPRVVVEAISGQQVASDFEAL
                     EQLADISGVVVPQAVNGLQEAPIRHSLLVTVADMQQAVEAYLGV"
     gene            1973..3274
                     /locus_tag="TV191_000806"
     CDS             1973..3274
                     /locus_tag="TV191_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEL1507339.1"
                     /translation="MTHNRKKILSLALPSMAENILQMLMGMIDNYLAAQIGLTAVSGI
                     AIANNILTIYQALFIALGAAVSSLIARSVGEQNHSKEIDYMANAILVTGALSVLLGLM
                     SVVGHKSILAFLGAASLVARLGGQYLAIVGGMILSLGLFTSLGAIIRAKGQPSIPMKV
                     SLLTNLLNAVFSALSLYIWGFGVIGIAWSTVASRLIGVVILCHFLPIKEIIKRFANPL
                     DKEIFSLSLPAAGERLMMRAGDVLIVTIIVRFGTEALAGNAIGETLTQFNYMPGLAMS
                     TATVILVANQLGSGKGATIAKTVKETFLLATLMMLVMGLITYLLGPNLLPLFTADAKA
                     QQAGMVVLVFSLLGVPATAGTLVYTAAWQGIGQAKLPFYATTIGMWLVRISLGYFIGV
                     TLNYGVIGVWLATILDNATRWLILAVAFKKQQRQLFSDCHS"
     gene            3654..3962
                     /gene="rpsJ"
                     /locus_tag="TV191_000807"
     CDS             3654..3962
                     /gene="rpsJ"
                     /locus_tag="TV191_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEL1507340.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAEKIVETATRTGATVAGPVPLPT
                     ERSLYTIIRATHNYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            4260..4886
                     /gene="rplC"
                     /locus_tag="TV191_000808"
     CDS             4260..4886
                     /gene="rplC"
                     /locus_tag="TV191_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEL1507341.1"
                     /translation="MTKGILGEKVGMTQIFTESGEFIPVTVIEATPNVVLQVKTVETD
                     GYEAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNIEGLEVGAEITVDIFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVSPNRVFKNKHLAG
                     RMGGNRVTIQNLEIVQVIPEKNVILIKGNVPGAKKSLITIKSAVKAAK"
     gene            4911..5534
                     /gene="rplD"
                     /locus_tag="TV191_000809"
     CDS             4911..5534
                     /gene="rplD"
                     /locus_tag="TV191_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEL1507342.1"
                     /translation="MANVKLFDQTGKEVSTVELNDDIFGIEPNESVVFDVVISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSAKVAEDKFVAVESLSFAAPKTAEFAKVLSALSIDTKVLVLVEEGN
                     EFAALSARNLPNVAVATAATASVLDIVNADKLLVTKEAISTIEEVLA"
     gene            5534..5830
                     /locus_tag="TV191_000810"
     CDS             5534..5830
                     /locus_tag="TV191_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEL1507343.1"
                     /translation="MNLYDVIKKPVITEKSMYALEEGKYTFEVDTRAHKLLIKQAVEA
                     AFDGVKVASVNTVNVKPKAKRVGRYTGFTSKTKKAIITLTADSKAIELFAVEAE"
     gene            5848..6681
                     /gene="rplB"
                     /locus_tag="TV191_000811"
     CDS             5848..6681
                     /gene="rplB"
                     /locus_tag="TV191_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEL1507344.1"
                     /translation="MGIKVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVSLKNKAGRN
                     NNGRITVRHQGGGHKRHYRLIDFKRNKDGVEAVVKTIEYDPNRTANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPDADIKVGNALPLVNIPVGTVVHNIELKPGKGGELVRAAGA
                     SAQVLGQEGKYVLVRLQSGEVRMILGTCRATVGTVGNEQQSLVNIGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSNKLLVRRRNE
                     K"
     gene            6793..7071
                     /gene="rpsS"
                     /locus_tag="TV191_000812"
     CDS             6793..7071
                     /gene="rpsS"
                     /locus_tag="TV191_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEL1507345.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRR"
     gene            7087..7431
                     /gene="rplV"
                     /locus_tag="TV191_000813"
     CDS             7087..7431
                     /gene="rplV"
                     /locus_tag="TV191_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEL1507346.1"
                     /translation="MAEITSAKAMARTVRVSPRKTRLVLDLIRGKKVADAIAILKFTP
                     NKAARVIEKTLNSAIANAENNFGLEKANLVVSETFANEGPTMKRFRPRAKGSASPINK
                     RTTHVTVVVSEK"
     gene            7444..8097
                     /gene="rpsC"
                     /locus_tag="TV191_000814"
     CDS             7444..8097
                     /gene="rpsC"
                     /locus_tag="TV191_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEL1507347.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFINK
                     ELAEASVSTIEIERAVNKVIVSLHTAKPGMVIGKGGANVDALRAQLNKLTGKQVHINI
                     IEIKQPDLDAHLVGENIARQLEQRVAFRRAQKQAIQRTMRAGAKGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            8101..8514
                     /gene="rplP"
                     /locus_tag="TV191_000815"
     CDS             8101..8514
                     /gene="rplP"
                     /locus_tag="TV191_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEL1507348.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVSFGEYGLQATTSSWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEVAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            8524..8730
                     /locus_tag="TV191_000816"
     CDS             8524..8730
                     /locus_tag="TV191_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEL1507349.1"
                     /translation="MKLEEIKKFVAELRGLSQEELAKKENELKKELFDLRFQAAAGQL
                     DQTARLNEVKKQIARVKTVQSEMK"
     gene            8755..9018
                     /gene="rpsQ"
                     /locus_tag="TV191_000817"
     CDS             8755..9018
                     /gene="rpsQ"
                     /locus_tag="TV191_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011983253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEL1507350.1"
                     /translation="MMERNQRKTLVGRVVSDKMDKTITVIVETKRNHPVYGKRINYSK
                     KYKAHDEKNLAKEGDIVRIMETRPLSATKRFRLVEIVEEAVII"
     gene            9043..9411
                     /gene="rplN"
                     /locus_tag="TV191_000818"
     CDS             9043..9411
                     /gene="rplN"
                     /locus_tag="TV191_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEL1507351.1"
                     /translation="MIQQETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRPDGSYIKFDDNAAVIIRDDKTPRGTRIFGPV
                     ARELREGGYMKIVSLAPEVL"
     gene            9495..9800
                     /gene="rplX"
                     /locus_tag="TV191_000819"
     CDS             9495..9800
                     /gene="rplX"
                     /locus_tag="TV191_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEL1507352.1"
                     /translation="MFVKKGDKVRVIAGKDKGVEAVVLKALPKVNKVIVEGVAIIKKH
                     QKPNSENPQGAIVEKEAPIHASNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            9824..10366
                     /gene="rplE"
                     /locus_tag="TV191_000820"
     CDS             9824..10366
                     /gene="rplE"
                     /locus_tag="TV191_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEL1507353.1"
                     /translation="MANRLKEKYTNEVIPALTEKFNYTSVMAVPKVEKIVLNMGVGDA
                     VSNAKNLEKAAAELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKVRGLDIVIVTT
                     ANTDEESRELLKGLGMPFAK"
     gene            10382..10567
                     /locus_tag="TV191_000821"
     CDS             10382..10567
                     /locus_tag="TV191_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HEL1507354.1"
                     /translation="MAKKSMIAKNKRPAKYSTQAYTRCEKCGRPHSVYRKFKLCRVCF
                     RELAYKGQIPGVVKASW"
     gene            10900..11298
                     /gene="rpsH"
                     /locus_tag="TV191_000822"
     CDS             10900..11298
                     /gene="rpsH"
                     /locus_tag="TV191_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEL1507355.1"
                     /translation="MVMTDPIADFLTRIRNANQVKHEVLEVPASNIKKGIAEILKREG
                     FIKNVEVIEDGKQGIIRVFLKYGQNGERVITNLKRVSKPGLRIYSKREDVPKVLNGLG
                     IAIISTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            11620..12156
                     /gene="rplF"
                     /locus_tag="TV191_000823"
     CDS             11620..12156
                     /gene="rplF"
                     /locus_tag="TV191_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEL1507356.1"
                     /translation="MSRIGNKVIIIPAGVEIINNDNVVTVKGPKGELTREFNKNIEIK
                     VEGNEMTLVRPDDSKEMKTIHGTTRANLNNMVVGVSEGFKKELEMKGVGYRAQLQGSK
                     LVLSVGKSHQDEVEAPEGITFTVANPTSISVEGINKEVVGQTAAYIRSLRSPEPYKGK
                     GIRYVGEYVRLKEGKTGK"
     gene            12259..12615
                     /gene="rplR"
                     /locus_tag="TV191_000824"
     CDS             12259..12615
                     /gene="rplR"
                     /locus_tag="TV191_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEL1507357.1"
                     /translation="MISKPDKNKIRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVVVGKLVAERAVAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            12634..13128
                     /gene="rpsE"
                     /locus_tag="TV191_000825"
     CDS             12634..13128
                     /gene="rpsE"
                     /locus_tag="TV191_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEL1507358.1"
                     /translation="MAFKDNAVELEERVVAINRVTKVVKGGRRLRFAALVVVGDGNGH
                     VGFGTGKAQEVPEAIRKAVEAAKKSMIEVPMVGTTIPHEVYTNFGGAKVLLKPAVEGS
                     GVAAGGAVRAVIELAGIADITSKSLGSNTPINIVRATVEGLKQLKRAEEVAALRGISV
                     SDLA"
     gene            13143..13325
                     /gene="rpmD"
                     /locus_tag="TV191_000826"
     CDS             13143..13325
                     /gene="rpmD"
                     /locus_tag="TV191_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002959367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEL1507359.1"
                     /translation="MAQIKITLTKSPIGRKPEQRKTVVALGLGKLNSSVIKEDNAAIR
                     GMVTAISHLVTVEDVK"
     gene            13527..13967
                     /gene="rplO"
                     /locus_tag="TV191_000827"
     CDS             13527..13967
                     /gene="rplO"
                     /locus_tag="TV191_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEL1507360.1"
                     /translation="MKLHELKPAKGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRIPKRGFTNINTKEYALVNLDQLNAFEDGTEVTPVVLKEAGIV
                     RAEKSGVKILGNGELTKKLTVKAAKFSKSAEAAITAKGGSIEVI"
     gene            13984..15288
                     /gene="secY"
                     /locus_tag="TV191_000828"
     CDS             13984..15288
                     /gene="secY"
                     /locus_tag="TV191_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEL1507361.1"
                     /translation="MFLKILKDALKIKNVRNKIFFTIFIILIFRIGTHITVPGVNAKS
                     LEQLSELPFLNMLNLVSGNAMRNFSVFSMGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYISLVLAFAQSIGITAGFNTLSSVALVKTPDVRTYLLIGALLTTG
                     SVIVTWLGEQITDKGFGNGVSMIIFAGIISSIPNAIATIREDYFVNVKSGDLQSSYIV
                     VGILILAVLAIVFFTTYVQQAEYKIPIQYTKLVQGAPTSSYLPLKVNPAGVIPVIFAS
                     SITTIPSTIIPFFQNGRDIPWLTTLQGIFNYQSPTGMIVYALLIILFSFFYTFVQVNP
                     EKTAENLQKNSSYIPSVRPGRETEEFMSSLLKKLATVGAIFLAFISLVPIAAQQALNL
                     SSSIALGGTSLLILISTGIEGMKQLEGYLLKRKYVGFMNITE"
     gene            15440..16081
                     /locus_tag="TV191_000829"
     CDS             15440..16081
                     /locus_tag="TV191_000829"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEL1507362.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVETFELIHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGDLVPDEVTNGIVKERLAQADIKEKGFLLDGYPRTIEQAHALDETLK
                     ALGLTLDGVINIEVDPASLIDRLSGRIINKKTGETFHKIFNPPVGDYKEEDFYQREDD
                     KPETVKRRLDVNIAQGEPIIKHYRQAGIVRDIDGNKDISEVFADIKKVIENLK"
     gene            16199..16417
                     /gene="infA"
                     /locus_tag="TV191_000830"
     CDS             16199..16417
                     /gene="infA"
                     /locus_tag="TV191_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEL1507363.1"
                     /translation="MAKEDVIEIEGKVVETMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILVGDRVTVEMSPYDLTRGRITYRFK"
     gene            16443..16559
                     /gene="rpmJ"
                     /locus_tag="TV191_000831"
     CDS             16443..16559
                     /gene="rpmJ"
                     /locus_tag="TV191_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEL1507364.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPTNPKHKQRQG"
     gene            16577..16942
                     /gene="rpsM"
                     /locus_tag="TV191_000832"
     CDS             16577..16942
                     /gene="rpsM"
                     /locus_tag="TV191_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEL1507365.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGVSEDIR
                     VKDLTSDQEDAIRREVDTIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            16960..17343
                     /gene="rpsK"
                     /locus_tag="TV191_000833"
     CDS             16960..17343
                     /gene="rpsK"
                     /locus_tag="TV191_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEL1507366.1"
                     /translation="MAKPTRKRRVKKNIESGVAHIHATFNNTIVMITDVHGNALAWSS
                     AGALGFKGSRKSTPFAAQMAAEAAAKSAQEHGLKTVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            17390..18328
                     /locus_tag="TV191_000834"
     CDS             17390..18328
                     /locus_tag="TV191_000834"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEL1507367.1"
                     /translation="MIEFEKPIITKIDENKDYGRFVIEPLERGYGTTLGNSLRRVLLS
                     SLPGAAVTSIRIDGVLHEFDTIPGVREDVMQIILNVKGLAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIELVNPDHYLFTIADGYTLKASMTVAKKRGYVPAEGNKKDDAPVG
                     TLAVDSIYTPVKKVNYQVEPARVGSNDGFDKLTIEIMTNGTIIPEDALGLSARVLIEH
                     LNLFTDLTDVAKATEVMKEAEKVNDEKVLDRTIEELDLSVRSYNCLKRAGINTVFDLT
                     EKSEPEMMKVRNLGRKSLEEVKVKLADLGLGLKNDK"
     gene            18343..18729
                     /gene="rplQ"
                     /locus_tag="TV191_000835"
     CDS             18343..18729
                     /gene="rplQ"
                     /locus_tag="TV191_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEL1507368.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAYVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            complement(18947..19178)
                     /locus_tag="TV191_000836"
                     /pseudo
     CDS             complement(18947..19178)
                     /locus_tag="TV191_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195628.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            20034..21284
                     /locus_tag="TV191_000837"
     CDS             20034..21284
                     /locus_tag="TV191_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507369.1"
                     /translation="MSIDMYLSLSEEQAQSVEAVLARRQTAYQSLQETLIQLISNSPD
                     LSGRTYDSAKAYSSQVLIPLLKGCMLLDEAIITACKRLPSEYRSQVDQIDLKESDLVE
                     RIAQFDHVIGRYMDLISIEYSREEPSYSYISHLRSAEQLHRAVKRRLEEILRRLRHFD
                     TNSVHLFSTIQTLAAAVQIGMRQARTSWHAGSQVFVISEDMAWADTINSKWSKSKGLS
                     YLSDYVYDPDVLSKRAAINHSWIKTGYTMSKNFGKAVSKDYTKASFLSYGKAAKATGW
                     TSMAVDTGITSVREYNKKNSRAYGSEGKALIHASVAQIKSMGPIEGAIIGSKAGPWGA
                     LMGFVTGGINVTWGVVHPESKDNMFLWIQDKMDDVYDSIVQTDLGKGTHHAKESVKGH
                     IGRAIVRTWDFVSQSFGKGVGYDI"
     gene            21274..22105
                     /locus_tag="TV191_000838"
                     /pseudo
     CDS             21274..22105
                     /locus_tag="TV191_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677217.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         6775 a         4003 c         4920 g         6407 t
ORIGIN      
        1 agcaatagtc aagtcacctt tcactaagaa aaatcacttg attattgctt agttttttct
       61 aatggaggat ttttagttta gaagctttga gtttagacct caaaacttag atatggaatt
      121 cgaaaggcag tcactgctgt caacattact ttgggaaagt tcctataaga gacttttcat
      181 tagactgaag tagcttcaat agctctaaaa ctacctagac tcaagtaaca acaagtcctt
      241 agaattgatt ttctaagggc ttttttgctg cctcaaggta aagacatgtt cagcaacaaa
      301 ttgactggct agaccagtcc tttatttatg ctgatggctt gagactgctg ggttattagc
      361 acagaaaatg gctgtctcca aatcctagaa ggcttatgat tggaatatga tataatagtc
      421 aaaagaaatg atgaggtgat gtgaagcaat gccaatgatg taccaatcaa caagaaatgc
      481 agctaataag gtaacagcta gtcaagcgat tttaagtggc ctagcagatg atggtggctt
      541 gtttactcct acaagcatgc cagtgctgga tctagatttt gaggagctaa agaccaagtc
      601 ctatcaagag gttgccaagc ttattttatc agcctttttt gatgactata ctgaagcaga
      661 attagatgct tgtatctctt ctgcctatga tgataagttt gatacagcag tgatagcacc
      721 tctagctacg ttaaaggatt atcataattt ggagctattt catggctcaa ccatcgcatt
      781 taaggacatg gctctatcta ttttgcctta tctcttgaca actgctgcta aaaagcaagg
      841 tgtggagcga aaaattgcga ttttaaccgc tacctcaggt gatactggta aggcagcaat
      901 ggcaggcttt gttgatgttc cgggaacgga tattattgtc ttttatccta agtcaggcgt
      961 tagcaggatt caggagctgc agatgatcac acaggccggt cacaataccc atgttgtggc
     1021 gattgaaggc aattttgatg atgctcaaac agaggtcaag cgcctgttta atgaccctga
     1081 tttgcgtgag cggctagcag ctcaacagat acagctgtct tcggccaatt cgatgaatat
     1141 tggtcgtttg attcctcagg ttgtctatta tatttatgct tatgcccagt tggtaaggca
     1201 tcagcgactt gaagctggag agacgattaa catagtagtg ccgacaggaa attttggcaa
     1261 tctactggtt gcctactacg ccaaagaaat tggacttcct gttgccaaat tcatctgtgc
     1321 ttccaatgaa aacaatgtct tgacagattt ctttgctagt ggtaggtatg ataaaaagcg
     1381 tcccttcaag gtgactacta gtccatcaat ggatattttg gtgtcttcaa atttagagcg
     1441 cttggttttt tatttactag gcaatgatgc ccaaaagaca gcagtattaa tgaagagctt
     1501 ggcagaaaca ggtcagtatc agctagctga tgcagatcag tctatccttg atttatttgc
     1561 ggcaggcttt gcaacagagc aagagactgc taaagagatc aaaacgatat ttgagtctga
     1621 tcattatgtg cttgacccac atacagctgt agcttcagct gtttatcgtg cttatcggga
     1681 gcaatcaggt gactctagac cgactattgt tgcgtcaact gctagtcctt ataagtttcc
     1741 gcgggtagtt gtggaagcta ttagtggtca gcaggttgcc agtgattttg aggcgcttga
     1801 gcagttggct gatatatcag gtgtagtcgt gccacaagcg gtcaatggct tacaggaggc
     1861 gcccattcgt catagccttt tagtgacagt agcagatatg cagcaggcag tagaggctta
     1921 tcttggagta taggaggcat aaaggagctc cctttcaatt gatatgaata taatgactca
     1981 caatagaaaa aagatactgt ccttggccct tccatcaatg gcagaaaata tattgcaaat
     2041 gctgatggga atgatagaca attatttggc tgctcaaatt ggacttacgg ctgtttcagg
     2101 cattgcgatt gctaataata ttctgacgat ttatcaggcc ctttttatcg cattaggtgc
     2161 tgcagtctcc agtctcattg ctagaagcgt aggagagcaa aaccattcta aagaaatcga
     2221 ctacatggca aatgctatct tagtaacggg ggctctatca gttcttctag gcttgatgtc
     2281 cgtagtggga cataaaagca tattagcctt tctgggagca gctagtctgg tagctagact
     2341 tggtgggcag tatttagcca ttgtcggtgg aatgattctt agtcttggtc ttttcacgag
     2401 cttaggtgcg attattcgtg ctaagggcca gcctagcatt cccatgaagg tcagcctttt
     2461 aactaatttg ctaaacgctg tattttcagc cctttctctt tacatatggg gatttggagt
     2521 gatagggatt gcttggtcaa ctgttgcatc acgtctcatt ggagttgtta ttctatgtca
     2581 ctttcttcct attaaagaaa ttattaaacg ttttgctaat cccttagata aagagatctt
     2641 tagcctctct cttccagcgg ctggtgagcg gctcatgatg cgagctggtg atgtgctgat
     2701 tgttactatt attgttagat ttggaacaga ggccttggca ggcaatgcga ttggagaaac
     2761 cttaactcaa tttaattata tgccgggact tgctatgtca actgcgacag tcattttagt
     2821 tgccaatcag ttgggcagtg gcaaaggggc tacaatagcg aaaactgtaa aagaaacctt
     2881 tttgttagcc accctgatga tgcttgttat gggcttgatc acttatttgc taggccctaa
     2941 tctactgccc ttatttacag cagatgccaa ggctcagcag gctggtatgg ttgtcttagt
     3001 cttttctctt ttgggggtac cagcaacagc cgggaccttg gtttatacag cagcctggca
     3061 gggtatcgga caagctaagc ttccctttta tgcaacaacg attggtatgt ggctggttcg
     3121 gatttctttg ggctacttta ttggagtaac cttaaattat ggagtaatag gtgtttggct
     3181 tgcgactatt ttggacaatg ctaccagatg gctcattctt gcagtggctt ttaagaagca
     3241 gcaaaggcag cttttttcgg actgtcatag ctaaactttg tatttaggtc tcaagacttc
     3301 tgagtggtga ctttcctttt gggagtcagc cactgtcatc agaatgtaaa gtacgcctga
     3361 ggctctgttt gctaatagct tctcttatct gcggaagatc aaagaggatt gctggaacag
     3421 ctgaggtttg tcttcaatct ggcttgccct ttcttagggc aagttttttt gaaaaaatcc
     3481 cctgaaaggc ttgcaatgcc ttattaattc tgctattata ttatggtgct gtaaaaatac
     3541 agctttagct gtgatacgag aggttgcgac acgctcggtt gcattgccac gtgacaggtg
     3601 tcggttttct cgaggagcta gcctattatc gtaaatagac gagaggagaa aagatggcaa
     3661 acaaaaaaat ccgtatccgc ttgaaagcgt acgaacaccg tacacttgat acagcggcag
     3721 aaaaaatcgt tgaaactgca actcgtacag gtgcaacagt agctggacca gttccacttc
     3781 caactgaacg tagtctttac accattattc gtgcgactca caattataaa gattctcgcg
     3841 aacaatttga aatgcgtaca cacaaacgtc ttattgatat tgtgaaccca acgcaaaaga
     3901 ctgttgatgc acttatgaaa ttggaccttc caagtggtgt caacgtagaa atcaagcttt
     3961 aattgtttga aacatgagtg aggaacgagt tcatatctaa ttgaacacag gctaaactct
     4021 gtgtgaaaaa gagacacagc cgttctaatt ttaattagat tacggatgtg gctacctgta
     4081 ggtgtaaatc ttcctagaaa cagaagtttc ttcgtcagat ttcctatttt cactgtgagt
     4141 ttgacgcctt aagtatcttg ctttgagcat aaaaaacgct cgtaaaaaac ttttttgagc
     4201 ataaaaaacg ctcactaaaa actttttgaa atattattaa gaaaaggaat tattttctca
     4261 tgacaaaagg aatcttaggg gaaaaagtgg gaatgactca aatcttcact gaatccggtg
     4321 aatttatccc tgttactgtc atcgaagcaa ctccaaacgt tgtgcttcaa gttaagactg
     4381 ttgaaacaga cggttacgaa gcaattcaag ttggttttga tgataaacgt gaagtattga
     4441 gcaacaaacc tgccaaaggc catgtagcaa aagctaacac agctcctaag cgcttcattc
     4501 gtgaattcaa aaacattgaa ggcttagaag taggtgcaga aatcactgtg gatatcttcg
     4561 cagctgggga tgttgttgat gtaactggta cttcaaaagg taaaggcttc caaggtgtta
     4621 tcaaacgcca tggtcaatca cgtggtccga tggcccatgg ttctcgttac catcgtcgtc
     4681 caggttctat gggacctgtt tcaccaaacc gcgttttcaa aaacaaacat ttggcaggac
     4741 gcatgggtgg caatcgtgta actattcaaa atcttgaaat tgtacaagtt atcccagaaa
     4801 agaacgttat tcttattaaa ggtaacgtac caggtgctaa gaaatctctt atcaccatca
     4861 aatcagcagt taaagctgct aaataataag aaaggagaaa acagttaaaa atggcaaacg
     4921 taaaactatt tgaccaaact ggtaaagaag ttagcacagt tgaattaaat gatgatatct
     4981 ttggtatcga accaaacgaa tcagttgttt ttgatgttgt aatcagccaa cgtgctagcc
     5041 ttcgccaagg tactcatgcg gttaaaaacc gttcagcagt atcaggtggt ggacgtaaac
     5101 cttggcgtca aaaaggaact ggacgtgctc gtcaaggttc tatccgctca ccacaatggc
     5161 gtggtggtgg tgttgtcttt ggaccaactc cacgttcata tggatacaaa cttccacaaa
     5221 aagttcgtcg ccttgctttg aaatcagttt actcagcaaa agttgctgaa gataaatttg
     5281 tagctgtaga aagcctttca tttgcagcac caaaaacagc tgaatttgca aaggtgcttt
     5341 cagctcttag cattgataca aaagtacttg ttcttgttga agaaggaaat gaatttgcag
     5401 cactttctgc acgtaacctt ccaaacgtag ctgtggcaac agcagcgact gcaagtgttc
     5461 ttgatatcgt aaacgcagac aaacttcttg taacgaaaga agcaatctct acaattgagg
     5521 aggttcttgc ataatgaatt tgtacgacgt aatcaaaaaa ccagttatta ctgaaaaatc
     5581 aatgtatgcc cttgaagaag gtaaatacac atttgaagtt gacacacgtg cgcacaaact
     5641 gttaatcaag caagctgttg aagctgcatt tgacggagtt aaggttgcaa gcgtcaatac
     5701 tgttaacgtt aaaccaaagg ctaagcgtgt tggtcgttac acaggtttta cttcaaaaac
     5761 taaaaaggct atcatcactc ttacagctga ttctaaagca atcgagttgt tcgcagttga
     5821 agctgaataa tctaaggagg aaataacgtg ggtattaaag tttataaacc aacgacaaat
     5881 ggccgtcgta acatgacttc tttggatttc gctgaaatca caacaagcac acctgagaaa
     5941 tcattgcttg tttctcttaa aaacaaagct ggtcgtaaca acaatggtcg cattacagtt
     6001 cgtcaccaag gtggtggaca caaacgccat taccgtttga ttgacttcaa gcgtaacaaa
     6061 gatggtgttg aagcagttgt taaaacaatc gaatacgatc caaaccgtac tgcaaacatt
     6121 gcacttgtac attacactga cggagttaag gcttacatca tcgctcctaa gggtcttgaa
     6181 gtaggtcaac gtattgtttc tggaccagat gcagatatta aggttggtaa tgcacttcca
     6241 ttagtaaaca ttcctgttgg tacagttgtt cacaacattg agcttaagcc tggtaagggt
     6301 ggagagcttg tacgtgctgc tggagcttct gctcaagtac ttggtcaaga aggcaaatac
     6361 gttcttgttc gtcttcaatc aggtgaagtt cgtatgattc ttggaacatg tcgtgcaact
     6421 gttggtacag ttggtaacga gcaacaatca cttgttaaca ttggtaaagc aggacgtagc
     6481 cgttggaaag gtatccgccc aacagttcgt ggttctgtaa tgaaccctaa cgatcaccca
     6541 catggtggtg gtgaaggtaa agcaccagtt ggacgtaaag cgccatctac tccttggggt
     6601 aaaccagcgc ttggtcttaa aacacgtaac aaaaaagcta aatctaacaa gcttcttgtt
     6661 cgtcgtcgta acgaaaaata agcggcaaat ctagcataag cttattcaat cattccgcca
     6721 gctcggtaga gtttgagctt gctctcatgc tcaagccgct gtggtacatt atttaaagga
     6781 gaaaactaca aaatgggacg tagtcttaaa aaaggacctt tcgtcgatga gcatttgatg
     6841 aaaaaagttg aagctcaagc taatgacgaa aagaaaaaag taatcaaaac ttggtcacgt
     6901 cgttcaacga ttttcccaag tttcatcgga tatacaatcg cagtttatga tggccgcaag
     6961 catgtacctg tgtacattca agaagacatg gtaggtcaca agcttggtga atttgcacca
     7021 actcgtacct acaagggtca cgcagctgac gacaagaaaa cacgtcgtta ataggaggag
     7081 gacacaatgg cagaaattac ttcagctaaa gcaatggctc gtacagtgcg tgtttcacct
     7141 cgtaaaacac gtttagtact tgatcttatc cgcggtaaga aagttgctga tgcaatcgca
     7201 atcttaaaat tcactccaaa caaagcagct cgtgttattg agaaaactct taactcagca
     7261 attgctaacg cagaaaataa ctttggtttg gaaaaagcta acttggtagt atctgaaaca
     7321 tttgcaaacg aaggaccaac aatgaaacgt ttccgtccac gtgcaaaggg ctcagcgtca
     7381 ccaatcaaca agcgaacaac tcacgttaca gtagttgtat cagaaaaata aggaggtaaa
     7441 atcgtgggtc aaaaagtaca tccaattggt atgcgtgtcg gaatcattcg tgactgggat
     7501 gcaaaatggt atgctgaaaa agaatacgcg gattaccttc atgaagatct tgcaatccgt
     7561 aaattcatta acaaagaatt ggcagaggct tcagtttcaa caattgaaat tgagcgtgct
     7621 gtaaataaag ttattgtttc acttcacact gcaaagcctg gtatggttat cggtaaaggt
     7681 ggagcaaatg ttgacgctct tcgcgctcag cttaacaaat taactggaaa acaagtacac
     7741 atcaacatca tcgaaatcaa acagcctgat cttgatgccc accttgttgg tgaaaacatt
     7801 gctcgtcagc ttgagcaacg tgttgctttc cgtcgtgctc aaaaacaagc tattcaacgt
     7861 acaatgcgtg ctggagctaa gggaatcaaa actcaagttt caggtcgctt gaacggtgca
     7921 gatatcgcgc gtagcgaagg ctactcagaa ggaactgttc ctcttcacac acttcgtgca
     7981 gatattgact atgcttggga agaagcagat actacatacg gtaaacttgg tgttaaagtt
     8041 tggatttatc gtggtgaagt tcttccagct cgcaaaaaca ctaaaggagg caaataacag
     8101 atgttagtac ctaaacgtgt taaacaccgt cgtgagtttc gtggaaaaat gcgcggtgaa
     8161 gcaaaaggtg gaaaagaagt atcattcggt gaatatggtc ttcaagctac tactagctca
     8221 tggatcacta accgccaaat cgaagctgct cgtatcgcta tgactcgtta catgaagcgt
     8281 ggtggtaaag tttggattaa aatcttccct cacaaatctt atacagctaa agctatcggg
     8341 gttcgtatgg gttctggtaa gggtgcacct gaaggttggg tagcaccagt taagcgtggc
     8401 aaggttatgt ttgaggttgc tggtgtttct gaagaaatcg ctcgtgaagc acttcgtctt
     8461 gctagccaca agctaccagt taaatgtaaa ttcgtaaaac gtgaagcaga ataaggagaa
     8521 gacatgaaac ttgaagaaat caaaaagttt gttgctgagc ttcgtggctt gtctcaagaa
     8581 gagcttgcta agaaagaaaa cgaactcaaa aaagaacttt tcgaccttcg ttttcaagct
     8641 gcagcaggtc aactagatca aactgctcgt ttgaacgaag ttaaaaaaca aattgcacgt
     8701 gtaaagactg tgcaatctga aatgaaataa tagattggga aaggagtatt ctaaataatg
     8761 gaacgtaatc aacgtaaaac ccttgttgga cgtgttgtat ctgacaagat ggacaaaaca
     8821 atcactgtta tagttgaaac aaagcgtaac cacccagtct atggtaaacg tatcaactat
     8881 tctaaaaaat acaaagcaca tgacgaaaag aaccttgcta aagaaggcga tatcgttcgt
     8941 atcatggaaa ctcgtccact ttcagctaca aaacgcttcc gtcttgtaga aatcgtggaa
     9001 gaagctgtta ttatctaatc aaactaaaag gagacaattg aaatgattca acaagaaact
     9061 cgcttgaaag ttgctgataa tagcggtgct cgtgagatct tgactatcaa ggttcttggt
     9121 ggttcagggc gtaagtttgc taacatcggt gacgtcatcg ttgcatctgt aaaacaagct
     9181 actcctggtg gagcagttaa aaagggtgat gttgttaagg ctgttattgt tcgtacaaag
     9241 agtggtgctc gtcgtccaga cggttcatac atcaaatttg atgacaatgc ggctgtcatt
     9301 attcgtgatg acaagactcc tcgtgggact cgtatctttg ggcctgttgc acgtgaattg
     9361 cgtgagggtg gctacatgaa gatcgtatca cttgcaccag aagtacttta attttaatca
     9421 ttaaacaaac taagtcccct aggctagcct agggtgccca taggggcgta agaaaataat
     9481 aggagaaacc cataatgttt gtaaaaaaag gcgacaaggt tcgcgttatt gctggtaagg
     9541 acaaaggtgt tgaagctgtt gttcttaaag cacttccaaa agtaaacaaa gttattgttg
     9601 aaggcgtagc catcatcaaa aagcatcaaa aaccaaacag cgaaaatcct caaggtgcta
     9661 tcgttgaaaa agaagcacca atccatgcat caaacgttca agttcttgat aaaaatggtg
     9721 ttgctggacg cgttggttac aagtttgtag acggcaaaaa agttcgttac aacaaaaaat
     9781 caggcgaagt gcttgattaa tcacgaagga aaggagaagc ataatggcaa atcgtttaaa
     9841 agaaaaatat actaacgaag taattcctgc gttgacagag aagtttaatt acacatcagt
     9901 tatggctgtg ccaaaggttg agaaaatcgt tcttaacatg ggtgtgggtg acgctgtatc
     9961 aaacgctaaa aaccttgaaa aagctgctgc agaattggcg cttatctcag gtcaaaaacc
    10021 acttattact aaagctaaga aatcaatcgc tggcttccgt cttcgtgaag gtgttgctat
    10081 cggtgcgaag gtgacacttc gtggcgaacg catgtacgaa ttcctagaca agctagttag
    10141 cgtttcactt cctcgtgttc gtgacttcca tggtgttcca acaaaatcat ttgatggtcg
    10201 tggtaactac actcttggtg tgaaagaaca gcttatcttc ccagaaatca actttgatga
    10261 tgttgataaa gtgcgtggtc ttgatattgt tatcgtaaca actgctaaca ctgacgaaga
    10321 atcacgtgaa ttgcttaaag gtcttggaat gccttttgca aaataatagg gggtaactaa
    10381 attggctaaa aaatctatga ttgctaaaaa caaacgtcct gcgaagtatt ctacacaagc
    10441 ttacactcgt tgtgaaaaat gtggacgtcc acattctgtt taccgcaagt ttaagctttg
    10501 ccgcgtttgc ttccgcgagt tggcttacaa aggccaaatc ccaggtgttg ttaaagcgtc
    10561 ttggtaaaat gatgatgtga gagcgttaag ctacctaagc aaaaatagga aaattgacga
    10621 agagtctaaa tactctagga aattttgcac ctaaaggtag tagcttgaac tcagttcaaa
    10681 tgaacaaata atactatcag atattatgtc tgattcgatg caaaggcaaa gtgtcaattt
    10741 gaacacgggc gaaagccggt gtcaaaaaga taaacattcc ttggaggttt tccctcctgc
    10801 ggaagtttcc tattttgact ttggctttta gcgccctttg tatcatcgat taactagcaa
    10861 gtgcagcttg caaactacta gtaagaggag aataataaaa tggttatgac tgacccaatt
    10921 gcagactttt tgacacgtat tcgtaatgct aatcaagtaa agcatgaagt gttagaagta
    10981 cctgcatcaa atattaaaaa agggattgca gaaatcctta agcgtgaagg ctttatcaaa
    11041 aacgttgaag ttattgaaga tggcaaacaa ggaattattc gcgtatttct taagtacggt
    11101 caaaatggtg aacgtgtcat cactaactta aaacgtgttt caaaaccagg tcttcgtatt
    11161 tattctaagc gtgaggatgt tccaaaggtt cttaatggac taggaattgc aattatttca
    11221 acttcagaag gtcttttgac tgataaagaa gctcgtcaaa agaacgttgg tggagaagtt
    11281 atcgcatacg tttggtaatt taagagacaa aagccgtaac gaacaatcta aaattagaaa
    11341 attattgtgg cttgcttgca aacaaaatag tttgtctatt ttagatggca gttcgtcggc
    11401 tgtgctcaaa tgatgaacac tatcaacata gcaaacgtaa aagaactaat tgaacatggg
    11461 ctaaagtctg tgtgaaaaag ataaattttt ctagaaacct tggtttcata gtaatgtttc
    11521 ctattttcac tttgcctttt acgccctaag tatcttagtt caccccgtga aaactcgtcg
    11581 cgtaagcggc ctgataattt aacaggagaa aaaattaata tgtcacgtat tggtaataag
    11641 gttattatta tccctgcagg cgttgaaatc attaacaacg acaatgttgt tactgtaaag
    11701 gggcctaaag gagagctcac tcgtgagttt aacaaaaata ttgaaatcaa agtcgaagga
    11761 aacgaaatga ctcttgtacg tcctgacgac tcaaaagaaa tgaaaacaat tcatggtaca
    11821 actcgtgcaa acttgaataa catggttgtt ggagtttcag aaggtttcaa aaaagagctt
    11881 gaaatgaagg gtgtcggata tcgtgcacag cttcaaggct ctaagcttgt tctttcagta
    11941 ggtaaatctc accaagatga ggtggaagct ccagaaggga ttacatttac tgtagctaat
    12001 ccaacatcaa tttcagttga gggtatcaac aaagaagttg ttggtcaaac tgccgcttac
    12061 attcgtagcc tacgttcacc agagccttac aaaggtaaag gtattcgtta cgttggtgag
    12121 tatgtacgcc ttaaagaagg taaaacaggt aaataatgtt cttagtggaa tatggcatag
    12181 gcttgcttat gtcatgctct acaagctcaa ttgataattt gtcggaaaga caaacttaaa
    12241 tattaagagg tgaaaattgt gatttcgaaa ccagataaaa acaaaatccg ccaaaaacgc
    12301 catcgtcgcg ttcgcggtaa actctctgga actgctgatc gcccacgttt gaacgtattc
    12361 cgttctaata caggcatcta cgctcaagtt attgatgacg tagcgggtgt aacgctcgca
    12421 agtgcatcaa ctcttgataa agaagtttct aaaggaacaa aaactgaaca agctgttgta
    12481 gtcggcaaac ttgttgctga acgtgcggtg gctaaaggta tttctgaagt ggtgtttgac
    12541 cgcggtggat atctctatca tggacgtgtt aaagctttgg ctgatgcagc tcgtgaaaac
    12601 ggattgaaat tctaataggg aggacacaaa ataatggcat ttaaagataa tgcagttgaa
    12661 cttgaagaac gcgttgttgc tattaaccgc gttacaaaag ttgttaaagg tggacgtcgt
    12721 cttcgttttg cagctcttgt agttgttggt gatggaaacg gacatgttgg attcggtact
    12781 ggtaaagctc aggaagtacc agaagctatt cgcaaggcag ttgaagctgc taaaaagagc
    12841 atgattgaag tgccaatggt tggcacaaca attcctcacg aggtttacac taactttggt
    12901 ggagctaaag tattgttgaa gccagctgta gaaggttctg gagttgctgc tggtggtgcg
    12961 gtacgtgccg tcatcgaatt agcaggtatt gctgatatta cttcaaaatc tcttggttca
    13021 aacactccaa tcaacatcgt tcgtgcaact gttgaaggat taaaacagct taaacgtgca
    13081 gaagaagttg ccgcacttcg tggcatctca gtttctgact tagcttaaga aaggggatca
    13141 tcatggctca aattaaaatt actttgacta agtctccaat cggacgtaag ccagaacaac
    13201 gtaaaacggt tgttgccctt ggacttggta aattaaactc ttcagttatc aaggaagata
    13261 atgctgctat tcgtggtatg gtgacagcaa tttctcactt ggtgacagtt gaagatgtca
    13321 aataaagagt tagctagaaa tctctgattt cttgcattag catgcagaac cggcttttgt
    13381 gagttattcc tttgaatgac aagcagtggt cggttggtgc atatagcatc aggctatgac
    13441 atagcttgat catgtatagg cgagtttcta tggagagtcc tttcccttca tagaggcgct
    13501 agcattttac aaaaaaagga gaaaaaatga aacttcatga attgaagcct gccaaaggct
    13561 ctcgtaaagt ccgcaatcgt gttggacgcg gtacttcatc aggcaatggt aaaacatctg
    13621 gacgcggtca aaaaggtcaa aaggctcgta gtggtggtgg cgtacgtcta ggctttgaag
    13681 gtggacaaac acccttgttc cgtcgtattc caaagcgtgg atttacaaat atcaacacta
    13741 aagagtatgc tcttgttaac cttgatcaat taaacgcttt tgaagatggc acagaagtaa
    13801 ctccagttgt tcttaaggaa gctggaatcg ttcgtgctga aaagtcaggc gttaaaattc
    13861 ttggtaacgg cgaattgact aaaaaattga ctgttaaagc agcgaaattt tcaaaatctg
    13921 ctgaagcagc cattactgct aagggtggtt caatagaagt catctaatga ggggatactc
    13981 attatgttct taaaaatact caaagacgca ttgaagataa agaatgttag aaataaaata
    14041 ttttttacaa tctttattat ccttatattc cgtattggaa cacatatcac tgttcctggt
    14101 gtaaatgcaa aaagcttaga gcagctgagt gagcttccct tcctaaatat gttgaacttg
    14161 gtcagcggta atgcaatgag aaacttttca gttttctcaa tgggtgttag tccctatatt
    14221 acagcctcaa tcgttgttca gctattgcag atggatattt tgccgaagtt tgttgagtgg
    14281 ggaaaacaag gtgaggttgg ccgtcgtaag ctaaaccaag cgacgcgcta tatttccctt
    14341 gtcttagcct ttgctcaatc tatcggtatt acagcgggtt ttaacacctt atcaagtgtg
    14401 gccctagtca aaacaccaga tgtaagaacc tatttactga ttggagcttt actgacaaca
    14461 ggtagtgtga ttgtgacctg gcttggtgaa cagattaccg ataaaggctt tggtaatggg
    14521 gtgtctatga ttatctttgc aggtatcatt tcctctattc caaatgctat tgcaaccatt
    14581 cgtgaggatt attttgtcaa tgtgaagtca ggtgacctac agtcatctta tatcgttgtt
    14641 ggtattctca ttcttgcagt gcttgctatc gtctttttca caacgtatgt tcagcaggcg
    14701 gaatataaaa ttccaatcca atatacaaag cttgttcagg gtgcgcctac aagctcatac
    14761 cttcccttaa aagtaaatcc agctggtgtt attcccgtta tctttgccag ctcgattaca
    14821 acaattccaa gtacgattat cccgttcttt caaaatggca gagatattcc atggttgaca
    14881 actttgcaag gaatttttaa ctatcaatct ccaacaggaa tgattgttta tgccttgtta
    14941 attatcctgt tttcattctt ctataccttt gttcaagtaa atcctgagaa aacagctgaa
    15001 aatctacaga agaattcgtc ctatattcca agtgttagac ctggacgaga aacagaagaa
    15061 tttatgtcat ccttgctaaa gaaattggca actgtgggtg ctatcttcct agcatttata
    15121 tctcttgttc caattgcggc acaacaagct cttaacctat cttctagtat tgcattaggt
    15181 ggaactagct tgctgatttt gatttcgaca ggtatcgaag gtatgaagca gcttgaaggt
    15241 taccttctca agagaaaata tgtcggattt atgaatatta cagaatagaa tatgggttga
    15301 cactgtcaac cttctatttt gtttttaaat gacaataaga tttacagagc cttggttcct
    15361 atcttcttat tgccatttga aaacaaaaac aaggaaaact aaatttccta ttatctttat
    15421 gtcaaaagag gagaaaaaga tgaatctttt aatcatgggc ttacctggtg ccggtaaggg
    15481 tacacaggct gcaaagattg ttgaaacctt tgagcttatt catatttcaa caggagatat
    15541 gttccgcgct gcaatggcta atcagactga aatgggagtt cttgcgaaat cttatatcga
    15601 taagggtgat ttggtgccag atgaggtaac caatggtatc gttaaagaac gcttagcaca
    15661 agctgatatt aaagaaaagg gatttctttt agatggctat cctcgtacca ttgagcaggc
    15721 acatgcctta gatgaaacct taaaagcatt gggacttacg ttagatggtg tgatcaacat
    15781 tgaggttgac cctgcgtcac tcattgacag gcttagcggt cgtatcatca acaaaaaaac
    15841 aggggaaacc ttccataaga tctttaaccc accagtggga gactataagg aagaggactt
    15901 ttatcaacgt gaagatgata agcctgaaac agttaagcgt cgcttagatg ttaatattgc
    15961 acaaggtgag cctattatca agcattatcg tcaagcaggc attgttcgtg acattgacgg
    16021 aaacaaggac atttctgagg tctttgctga cataaaaaag gtcatcgaaa acctgaaata
    16081 aattccagaa aatcgcttgc gaaagtgatt ttatcgtgat atactagact agtctgactt
    16141 ataattgtta cctctgtgct cagaggacat caaatcgaaa tttagggggt acttttgcgt
    16201 ggcaaaagaa gacgtgattg aaattgaagg taaagttgtc gaaactatgc caaatgcaat
    16261 gtttactgtt gaattggaaa atggacatca gattttagca accgtatcag gaaagatccg
    16321 caaaaattac attcgtattt tagtgggtga tcgtgttact gtagagatga gtccttacga
    16381 cttgacacgt ggacgtatca cataccgctt taaatagtcg aaataattgg agggattaaa
    16441 acatgaaggt aagaccatcg gttaaaccaa tttgcgaata ctgcaaggtt attcgtcgta
    16501 acggtcgtgt tatggtaatt tgtccgacaa atccaaaaca caagcaacgt caaggataag
    16561 atagaaagga gaaaaaatgg ctcgtattgc tggagttgat attccaaatg ataagcgtgt
    16621 agtaatttca cttacctatg tgtatggaat tggtcttgca acatctaaaa aaatcttagc
    16681 agcagcaggt gtctctgagg acattcgtgt taaagatttg acatcagatc aagaagacgc
    16741 tatccgtcgc gaagtggata caattaaagt tgaaggtgat cttcgtcgtg aagtaaacct
    16801 aaatatcaag cgtttgatgg aaatcggttc atatcgtgga attcgtcacc gtcgtggact
    16861 tcctgtacgt ggacaaaaca caaaaaacaa tgctcgtact cgtaaaggta aagctgttgc
    16921 gattgcaggt aagaaaaaat aaaataggag gtaaaaaaat tggctaaacc aacacgtaag
    16981 cgtcgtgtga aaaagaacat cgaatctggt gttgcacata ttcacgctac atttaataac
    17041 actattgtta tgattacaga tgtgcacggt aatgctttag catggtcatc agccggtgct
    17101 cttggtttta agggttctcg taagtcaact ccttttgctg ctcaaatggc tgcagaggct
    17161 gctgcgaaat ctgcacaaga acatggttta aaaactgttg aagttactgt aaaaggtcct
    17221 ggttcaggtc gtgaatcagc tattcgtgcc ctagctgctg ccggtcttga agtaactgcc
    17281 attcgtgatg tgactcctgt accgcataat ggtgctcgtc ctccaaaacg tcgtcgtgta
    17341 taatcacagt aacaaatagt acacaagttt cgtttcgagg ggtgaaagaa tgattgagtt
    17401 tgaaaaacca ataataacaa aaattgatga aaataaagat tacggtagat ttgtaatcga
    17461 accacttgaa cgtggatatg gtacaactct aggtaattca cttcgtcgtg tactcttgtc
    17521 ttcacttcca ggtgcagctg ttacatcaat cagaattgat ggagtactac acgaatttga
    17581 tacaatccca ggtgtacgtg aagatgtcat gcaaattatc cttaatgtta agggacttgc
    17641 tgtgaaatca tacgtcgaag acgaaaagat tatcgagctt gatgtagaag gtccagcaga
    17701 ggtaacagct ggagatattc tcacagatag cgatatcgaa cttgttaacc ctgatcatta
    17761 tctttttact attgctgatg gttatacatt gaaggcttca atgactgtcg ctaaaaaacg
    17821 cggctatgta ccagcagagg gtaataaaaa agatgatgca cctgtgggga cgttggcagt
    17881 agattcaatc tatacgccag taaaaaaggt taattatcaa gttgagcctg ctcgtgtagg
    17941 tagtaatgac ggctttgata aattgactat tgaaatcatg acaaacggaa caattattcc
    18001 cgaagatgcc ttaggtttat ctgctcgagt tttaatcgaa cacttgaatt tatttactga
    18061 tttaacagat gttgcaaagg caactgaagt gatgaaggaa gctgaaaaag tgaacgatga
    18121 aaaggtactt gatcgcacta ttgaggaact tgatttgtcc gtacgctcat ataactgctt
    18181 gaaacgtgcc ggtattaata ctgtcttcga tttaacagaa aaatctgagc ctgaaatgat
    18241 gaaggtccgt aaccttggac gtaagagtct tgaggaagta aaggtcaagc ttgctgactt
    18301 aggtttggga ctaaaaaacg ataaataaca taggaggata aaatggctta ccgtaaacta
    18361 ggacgcacta gctcacaacg taaagcaatg cttcgtgact taacgacaga tcttttgatt
    18421 aacgaatcaa ttgtaacgac agaagcacgt gcaaaggaaa tccgtaaaac agttgaaaaa
    18481 atgattactc ttggtaaacg tggtgatctt catgctcgtc gccaagcagc tgcatacgtt
    18541 cgtaacgaaa tcgcatcaga aaactatgat gaagctactg ataaatacac atcaacaaca
    18601 gctcttcaaa aacttttctc tgaaattgcg cctcgttatg cagaacgcaa cggtggatac
    18661 actcgtatcc ttaaaacaga accacgccgc ggagatgctg ctccaatggc gattattgaa
    18721 ttagtttaat ttttatcaat tttgttgagt gttatgatga tggagcagtt cctttaagct
    18781 gttcttagtc tagctctggt ctaccgctag gacctttcct agcggtaaca ctcaccatgt
    18841 tgagaataag taacgcttgt ttacgaaagg tctctaagct gtaggtgccc ttcgtaagca
    18901 ggcgttttgt tgtgactcca tgttaactgt agtagatgac taatatctaa tatctagaga
    18961 ggatcagctt ggtgctctct tttctgatat taaaagcatt gggaatcttg gttttgaagt
    19021 tcttaaagct cctaaagcca aagtctttcg cttgatgtct ttggtcatct tgttagtggt
    19081 ctccggctta gcattggaat aaggtagttc aaagcattgg tgatgtaaga tctatacttc
    19141 ctgaaggtct tgaaaaccgt tttgaaggtg tgattgacct gtagcgggag tagattagat
    19201 caatggcgtt tggctgcttt gaaaatttag gtgacaattg tttttgtatc tttgtttaaa
    19261 aatggtataa tattaaaaca ttaaacaaaa tgtacataaa aaagccatat aaaagaatga
    19321 tattaagata atgtgatcaa tagttttaga aaatgaatgt gtaaggttaa ggtatgcccc
    19381 cttgatataa tgctagtttt acgaagaggc attctgtaca gacataatgc actcttacaa
    19441 atgatacggt aattgctcaa caaggcgcaa cagccttggc aaatgtaata tttgccttag
    19501 ctagcagcga attagttacg cttgatacat agacaagggt ttctggcata cagcagcaga
    19561 tggtgtgcct gtctcagaga gtggctgctt ggcttatcct attcatgttt taaaacttac
    19621 aggaggtgtt atgtggcctt tggtcgatgg atatttagct aggtgaacag ctattagctg
    19681 taaatatgag gtaggagctt tagtttgcat gatgttaaat gaattgaaac agacttagga
    19741 aagcttggct tagcaactat cacgcaagtt cttaacaacg ataaagatcg tatgggaaaa
    19801 tatgatcaag catcaacgga catgagatgt gttttatgaa gaaaccatta tacttttata
    19861 agacttattt agttgttttt ctttgcggac ttgtttgagg agtagtctac ataggcaata
    19921 ggctcaggct tacagcactt aggagacatt agagcatgag aagcactaac tggctagtga
    19981 tagaaaagta atagcacagt gtttttataa ctaacaagag gagtagacat tctatgagta
    20041 ttgacatgta tttgagctta tctgaagagc aggcacagag tgtagaggct gtcttagcta
    20101 ggcgacaaac agcctatcaa tccttacagg agaccttgat ccaattgatt tctaacagtc
    20161 ctgatttatc agggcggacc tatgattctg ctaaggctta tagtagtcaa gtgctaattc
    20221 ctttgttaaa ggggtgtatg cttttagatg aggcgattat aacagcctgt aagaggctac
    20281 ctagtgagta ccgtagtcag gtagaccaaa ttgatttgaa ggagagtgat ctggttgagc
    20341 gtattgccca gttcgatcat gtgattggtc ggtacatgga tttgattagt attgaataca
    20401 gtagagagga gcctagctat tcttatatct ctcatttaag atcagctgag cagctccatc
    20461 gggccgttaa gcggcgtctt gaggagatat tgcgaaggct aaggcatttt gataccaact
    20521 cagttcacct tttttcgact attcagactt tggcagcagc ggtacaaata ggcatgcgtc
    20581 aagctaggac ctcgtggcat gcaggaagtc aggtatttgt gatttcagag gatatggcat
    20641 gggccgatac gattaattct aagtggtcaa aaagtaaagg gttaagctat cttagtgatt
    20701 atgtttacga cccagatgtg ctctctaaga gagcagctat taatcactct tggattaaaa
    20761 caggctatac tatgtctaaa aattttggca aagctgtttc aaaagattat acaaaagcaa
    20821 gctttttgag ctatggtaag gcagccaagg cgactggctg gacttctatg gcagtagata
    20881 ctggaataac tagtgtaagg gaatacaata agaaaaatag tagagcctat ggcagtgagg
    20941 gcaaggcgct tattcatgct agtgtggctc aaatcaagag catgggacct atagaagggg
    21001 cgataattgg cagtaaagct ggaccttggg gagcattaat ggggtttgtt acaggaggca
    21061 ttaatgttac ttggggagta gtgcatccag agtctaagga caacatgttt ttatggatac
    21121 aagataaaat ggatgatgtt tacgattcga ttgttcagac agatcttggc aaagggacgc
    21181 accatgctaa agaaagtgtc aaaggtcata tcggtcgagc tattgtaagg acatgggact
    21241 ttgtcagtca atcatttggt aaaggagtgg gctatgacat ttaaagatca gctttttagt
    21301 gggacgtttg agcaatcaaa aaagattgtg tctaaaagta tattgacaga agaaggtgcg
    21361 cagattggag tattctcatc tatgagtcta tggaagagaa taacaggctt gatgatgttg
    21421 ccattatttg ctatttcata tggagtagga gttgtgttac ctgaacactt tcaacaatca
    21481 acagaaggag ttcaagctat ttcattggct gcaatagaga ttattgccag attaggacag
    21541 ttcagtcgat actttatcat ttgttttatt tgtatgtctg ttggattaat tattagtaat
    21601 atccttccaa agcctaacta ggcttatcaa ttattatatg gcaatgctac tcttattata
    21661 cttagtatta caactattat ctcagccttc cctttaactg ctggccttac aattgcagct
    21721 tttggctgga tcggtttttt gcttcagcta ttgctttgcc tttatttgtg gaaggtttgt
    21781 gtcatagata agtgtcaaca gctacgcaca gcaatttatc aagaaagcac catagcacct
    21841 gattggggca gtaagctagt aagctttatt aagtcttatg gtggtatctt attaggcctc
    21901 tctgttctca accgctggac tctcaatcta ggagagctag tcaaggaaag ccctggtttg
    21961 ttgagttttc tgtacggctg gatttttcta ttgttcatgt ttttgatgct atttgcactg
    22021 ggtcaagcgt taaaaaatac catcatagcc tattattttt ttagatatca aaaagaatac
    22081 cgcaagcatt ttaatataag cgatg
//
LOCUS       DARYXW010000027        21770 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.027, whole genome shotgun sequence.
ACCESSION   DARYXW010000027 DARYXW010000000
VERSION     DARYXW010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21770)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21770)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21770
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.027"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            70..1248
                     /locus_tag="TV191_000839"
     CDS             70..1248
                     /locus_tag="TV191_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002996017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1507370.1"
                     /translation="MKKRILSAVLVSGVTLGTATTVGADDLDSKIALQNSVISNLNKE
                     QKAAQDRMKTLQSQVSSLQSEQERLVAKNGELEARSAQFEQEIQVLASQIIARNEKLK
                     GQARSAQKGNTLGYLNALLNSKSISDVITRLVAINRAVSANAQMLEKQKADKLSLEEK
                     QQENQEAINTIASNITAIESNQVALKTQQADLEVAKVDLALQLATAEDEKASLITRKE
                     AAEQAAAQAKAQAEQEAAARAAQAQAQAQSVAAAQAAVTQAVPTPAPAQAQPVVAPAA
                     MVSTPAVSYAYDPSNPYPVGQCTWGVKALAPWVGNYWGNGGQWASSAAAAGFRVGATP
                     MVGSVVVWNDGGYGHVAYVTGVQGGQIQVMEANYAGNQSIGNYRGWFSPGAVSYIYPN
                     "
     gene            1353..2315
                     /locus_tag="TV191_000840"
     CDS             1353..2315
                     /locus_tag="TV191_000840"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEL1507371.1"
                     /translation="MSYSDLKLFALSSNKELAEKVAAAMGIQLGKSTVRQFSDGEIQV
                     NIEESIRGHHVFILQSTSSPVNDNLMEILIMVDALKRASAEKISVVMPYYGYARQDRK
                     ARSREPITSKLVANMLEVAGVDRLLTVDLHAAQIQGFFDIPVDHLMGAPLIADYFDRH
                     GLVGDDVVVVSPDHGGVTRARKLAQFLQTPIAIIDKRRSVDKMNTSEVMNIIGSVEGK
                     KCILIDDMIDTAGTICHAADALAEAGATAVYASCTHPVLSGPALDNIQKSAIEKLIVL
                     DTIYLPEERLIDKIEQISIADLIAEAIIRIHEKRPLSPLFELGK"
     gene            2675..3445
                     /gene="recO"
                     /locus_tag="TV191_000841"
     CDS             2675..3445
                     /gene="recO"
                     /locus_tag="TV191_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEL1507372.1"
                     /translation="MRIQRSLGIVLYNKNYREDDKLVKIFTEAAGKRMFFVKHIGRSK
                     LAPVVQPLTAADFLLKINDSSLSYIEDYNQVEAYRHINEDFFRLSYASYVLALADAAI
                     PDNEPDPQLFAFLKKTLDLMEEGLDYDILTNIFEVQILDRFGVRMNFHDCVFCHRTNL
                     PFDFSHKYSGVLCPQHYHEDERRYGLDPNVIYLLNRFQTLNIDELKTISVNTGMKKKL
                     RLFIDALYEDYVGIRLKSKVFIDDLAKWGDIMKNKQGL"
     gene            3561..4568
                     /gene="plsX"
                     /locus_tag="TV191_000842"
     CDS             3561..4568
                     /gene="plsX"
                     /locus_tag="TV191_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEL1507373.1"
                     /translation="MKKIAIDAMGGDYAPKAIVEGVNQAIESFSDIEIQLYGDQSRIE
                     SYLVKSDRVSIVHTDEKINSDDEPAKAIRRKKNASMVLAARAVKDGRADAVLSAGNTG
                     ALLAAGLFIIGRIKGVDRPGLLSTLPTVDGSGFDMLDLGANAENTAEHLHQYAILGSF
                     YAKHVRGIAKPRIGLLNNGTEATKGDSLRKEVYNFLASDSSLQFIGNVEARDLMSGVA
                     DVVVADGFTGNAVLKSIEGTAMSIMGQLKSAIAVGGVKAKFGALLLKSSLYDLKDTLD
                     YSSAGGAVLFGLKAPLVKSHGSSDAKAIFHTIKQVRTMLETDVVGQLVEEFSKESDVN
                     D"
     gene            4561..4809
                     /locus_tag="TV191_000843"
     CDS             4561..4809
                     /locus_tag="TV191_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514702.1"
                     /note="carries the fatty acid chain in fatty acid
                     biosynthesis; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEL1507374.1"
                     /translation="MTEEVILEKIIALIKKQRSRIDFDITEKTALKDDLGVDSIELVE
                     FVINIEDEFGIDIPDEDVDGMVSMGDMLNYLVKRLNQS"
     gene            4959..5669
                     /locus_tag="TV191_000844"
     CDS             4959..5669
                     /locus_tag="TV191_000844"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEL1507375.1"
                     /translation="MSNQLIYSGKAKDIYETADDGIVLISYKDQVTMLNGAHKEMIEG
                     KGSLNNQISALIFDRLNRVGVSTHFIKQLSETEQLNKRVAIIPLEVVLRNVAAGSFSK
                     RFGVKEGQALDEPIIELYYKNDALDDPFINDEHVSFLKLATDEQIAYIKQETHRINAY
                     LKEWFASVGLTLVDFKLEFGFDKEGMLILADEFSPDNCRLWDNAGRHMDKDVFRRQLG
                     SLTQAYETVLERLRALDQ"
     gene            5848..9588
                     /locus_tag="TV191_000845"
     CDS             5848..9588
                     /locus_tag="TV191_000845"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEL1507376.1"
                     /translation="MNKRIFVEKKADFQIKAQVLLKELKHQLQLKTLVDLRIVQVYDV
                     FHLDQELLLTAIKHVFSEQVTDQVLSEEALQADLKRYAFFAIEALPGQFDQRAASSQE
                     ALLLLGASTDVTVLTSQLYLVNQDIAAEELEALKQYLLNPVDSRFKDILAGLDDQDFS
                     VADKVIPTLDVFNDYTAENLARYRSEQGLAMEVEDLLFIQDYFKTKGRVPTETELRVL
                     DTYWSDHCRHTTFETELKTLDFSASHFEKQLQATYETYLAMRDELGRSERPQTLMDMA
                     TIFGRYERANGRLEDLEVSDEINAYSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRLSGAGDITSPLSETRKGKLPQQVISRQAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKENVVREKPRTGDVVVLLGGK
                     TGRDGIGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRRGDVTRLIKKSNDF
                     GAGGVCVAIGELAAGLNINLDKIPLKYAGLNGTEIAISESQERMAVVICPKDLEAFMS
                     ACHKENIHAAVVAAVTEKPNLVMTWNGQTIVDIERSFLETNGVRVSVAAKVVDSGAPI
                     PEARQTTAETLEADTIAVLSDLNHASQKGLQTLFDSSVGRSTVIHPLGGRYQMTPVEG
                     SVQKLPVQHGVTKTVSVIAQGYHPYIAEWSPYHGAAYAVIEATARLVATGSHWHKARF
                     SYQEYFQRMDKQAERFGQPVAALLGAIEAQVQLGLPSIGGKDSMSGSFEELTVPPTLV
                     AFGVTTAHVDHILSPEFKAAGENIYYIPGQAISEVIDFELIKSNFMTFEAIQKKHNIS
                     SASAVKYGGVVEALALAAFGNRLGACVTLPELDRSLTAQLGGFIFTSKEEITGVIKLG
                     QTTSDFTLVVNDVKLSGARLLKAFEGSLEQVYPTVFQQAGELKPVPVVTTALAAQFKE
                     KIAQPVVYIPVFPGTNSEYDSAKAFEREGARVNLVPFVTLNEAAIDASVDTMVDHIHQ
                     AHIIFLAGGFSAADEPDGSAKFIVNILLNEKVRMAIDAFIEKGGLIIGICNGFQALVK
                     SGLLPYGRFEAVHEASPTLFYNDANQHVAKMVETRIANTNSPWLAGVRVGDIHAVAVS
                     HGEGKLVVTERELAELCKNGQIFSQYVDLDGNPSMDSRYNPNGSVNAIEGLTSKNGQI
                     IGKMGHSERFEEGLFQNIPGNKDQWLFRSAVHYFRGDHVGID"
     gene            9707..11164
                     /locus_tag="TV191_000846"
     CDS             9707..11164
                     /locus_tag="TV191_000846"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003104332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEL1507377.1"
                     /translation="MTYDVKSLNEECGVFGIWGHPHAAQVTYFGLHSLQHRGQEGAGI
                     ISNDNGELHQHRDVGLLSEVFKDSSDLDKLKGHAAIGHVRYATAGTASINNIQPFLYR
                     FTDAQFGLCHNGNLTNAMSLKKALESEGAIFNASSDTEILMHLIRRSHHPEFLGKVKE
                     ALNTVKGGFAYLLMTENQLIAALDPNGFRPLSIGRMKNGAWVVSSETCAFEVVGAEWV
                     RDVMPGEVIIIDDQGITYDCYTTTTQLAICSMEYIYFARPDSTIAGVNVHTARKRMGK
                     RLAQEFQHEADIVVGVPNSSLSAAMGFAEASGLPNEMGLVKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVNLLREAGATEVHVAIGSPELKY
                     PCFYGIDIQTRRELISANHTAAEVCDIIGADSLTYLSLDGLIEAIGLDTKAPNGGLCV
                     AYFDGQYPTPLYDYEEAYLKSLEEKVSFHIDQVTK"
     gene            11221..12243
                     /locus_tag="TV191_000847"
     CDS             11221..12243
                     /locus_tag="TV191_000847"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEL1507378.1"
                     /translation="MSKNAYAQSGVDVEAGYELVERIKKHAERSKRLGVMGGLGGFGG
                     LFDLSKTGVKEPVLVSGTDGVGTKLMLAIQYDKHDTIGQDCVAMCVNDIIAAGAEPLY
                     FLDYLAAGKNEPAKLEQVIAGIAEGCVQAGAALIGGETAEMPGMYGQDDYDLAGFAVG
                     IAEKSQLIDGSRVAEGDHLLGLASSGVHSNGYSLVRRIFAGYTGEELLPELDGKKLKE
                     VLLEPTRIYVKAVLPLIKSGLVAGIAHITGGGFIENLPRMFSKELAAEIEEASLPVLP
                     IFKVLETYGKINHEEMFEIFNMGIGMVLAVKPEHVEQVKACLDEPVYDIGRVVTRTVA
                     SVVMKP"
     gene            12240..12797
                     /gene="purN"
                     /locus_tag="TV191_000848"
     CDS             12240..12797
                     /gene="purN"
                     /locus_tag="TV191_000848"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEL1507379.1"
                     /translation="MTRIAVFASGNGSNFQTIAEQFPVAFVFSDHCDAHVLSRACALG
                     VLSYSFELKDFENKQAYEQTLVALLQRHQIDLIVLAGYMKIVSTTLLDAYEGKIINIH
                     PAYLPEFPGAHGILDAWQAGVSQSGVTVHWVDSGIDTGKIIKQVRVPRLSDDTLESFE
                     ARIHEAEYQLYPEVLDSLGVERLNR"
     gene            12944..14491
                     /gene="purH"
                     /locus_tag="TV191_000849"
     CDS             12944..14491
                     /gene="purH"
                     /locus_tag="TV191_000849"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEL1507380.1"
                     /translation="MTKRALISVSDKRGIVDLARELKHLGWDIISTGGTRLALEEAGV
                     VTVAIDDVTGFPEMMDGRVKTLHPLIHGGLLARRDIEHHLQAAKQNRIELIDLVVVNL
                     YPFKETICRPDVTYDVAVDMVDIGGPSLLRSAAKNHASVTVVVDPTDYPLVLGELAST
                     GSTSYQTRQSLAAKAFRHTAAYDAVIADYFTRQAGETKPEKLTLTYDLKQSMRYGENP
                     QQAADFYQRALPTTYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKERPTVVALKHM
                     NPCGIGQADDIETAWDFAYAADPVSIFGGIVVLNREVDLATAEKLHAIFLELIIAPGY
                     SKEALAVLTHKKKHLRILELPFAAQEASEIEAEYTGVLGGLLVQNQDVVTESPADWIV
                     VTKRQPNEQEMAALAFAWKTIKYVKSNAIVIANDHMTLGVGPGQTNRIASIRIAIAQA
                     TGQLEGAVLASDAFFPFADSIEEIAAAGIKAIIQPGGSIRDSESIAAANQHGITMIFT
                     GVRHFRH"
     gene            complement(14869..16023)
                     /locus_tag="TV191_000850"
     CDS             complement(14869..16023)
                     /locus_tag="TV191_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HEL1507381.1"
                     /translation="MKKVYQLLASGAILLGGNGAISSATTTISQGQSGIVHAAVLGDN
                     YPSKWKQGFGADPWNMYLRQCTSFVAFRLHSSNGFSLPRGYGNVESWGRIAKHQGYHV
                     DHTPRVGAVAWWDKGFNQSHALYGHVAWVAEVNGDTVIIEEYNYNAGQGPEKYHKRQI
                     HKHQVSGYIHFKDLDHNSTSHTQMLHASQAGSTRLAKSGTYYFSSQSPIKAEATLASP
                     DLAYYHTGQLVHYDQTLVADGYEWLSYIGHSGNHRYIPIHKLPVQPQQHSQASIDKPK
                     PVATTPIKVGDTVAFPGVFRVDQVAQNMIASSELAGGEPTSLNWIDSAPLHETDHKGR
                     IAGNQILQVGDYFVVSGTYKVLKVDQPSKGIYVQMGSRGTWLTIDKAKKV"
     gene            16414..17676
                     /gene="purD"
                     /locus_tag="TV191_000851"
     CDS             16414..17676
                     /gene="purD"
                     /locus_tag="TV191_000851"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEL1507382.1"
                     /translation="MKLLVIGSGGREHAIAKKLLESKGVEQVFVAPGNDGMTLDGIER
                     VDIDISEHSALIAFAKTNHIAWTFVGPDDALAAGIVDEFNQSGLKAFGPSRLAAELEW
                     SKDFAKQIMVKYGIPTAAYGTFSDFAKAKAYIEEKGAPIVVKADGLALGKGVVVAETV
                     EQAVEAARDMLLDNKFGDSGARVVIEEFLAGEEFSLFAFVNGDQFYLMPTAQDHKRAL
                     DGDKGPNTGGMGAYAPVPHLSQSVVDTAVETIVKPVLKGMMTEGRPYLGILYCGLILT
                     EDGPKVIEFNARFGDPETQVILPRLTSDFAQNITDILEGNTANITWSDEGVTLGVVLA
                     SNGYPLAYKKGVLLPAKTTGDIITYYAGVKLAENGKALLSNGGRVYMLVTTAVTVPAA
                     QEKIYTELAQQNTEGLFYRNDIGRKAVK"
     gene            17905..18393
                     /gene="purE"
                     /locus_tag="TV191_000852"
     CDS             17905..18393
                     /gene="purE"
                     /locus_tag="TV191_000852"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEL1507383.1"
                     /translation="MKPIISIIMGSKSDWTTMQKTAEILDQFGLAYEKKVVSAHRTPD
                     LMFTYAEKARERGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGLDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALTALRILSIEDETIAEQLSHFHKEQGRIAEESTHE
                     LN"
     gene            18380..19453
                     /gene="purK"
                     /locus_tag="TV191_000853"
     CDS             18380..19453
                     /gene="purK"
                     /locus_tag="TV191_000853"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEL1507384.1"
                     /translation="MNSTKTIGIIGGGQLGQMMAISAIYMGHKVITLDPAADCPASRV
                     SEVIVAPYSDVEALRQLTERCDILTYEFENVDADALDTVVKEEQLPQGTELLRISQNR
                     IFEKDFLANKASAAVAPYKVVTSSLDLENLDFSKKYVLKTATGGYDGHGQVVIRSEAD
                     LEEANKLANTAECVLEEFVSFDREISVIVSGNGTDVTVFPVQENIHRNNILSKTIVPA
                     RISEAVSAKSQAMAVKIAEQLNLSGTLCVEMFVAGDEILVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGQPLPAVKLHAPAIMLNVLGQHMEQAQRYATENPSAHLHLYGKIE
                     AKHNRKMGHVTVFNSQSDEVEEF"
     gene            19468..19692
                     /locus_tag="TV191_000854"
     CDS             19468..19692
                     /locus_tag="TV191_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEL1507385.1"
                     /translation="MIKIIVHAFIENGETGVVEVVFASENQESISEKMTELQKQYPND
                     YLAIYDLPLDTDLSQLAHYPSIAIGKGEFE"
     gene            20289..21581
                     /gene="purB"
                     /locus_tag="TV191_000855"
     CDS             20289..21581
                     /gene="purB"
                     /locus_tag="TV191_000855"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEL1507386.1"
                     /translation="MLNRYSRPEMAKIWSEENKYRAWLEVEILADEAWAELGEIPKED
                     VAKIRANASFDINRILEIEEETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIVAEKAKEHKMTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNQERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCGKLGIRPQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMVTAYENVALWHERDISHSSAERIITPDTTILINYMLNRFGNIVKNL
                     TVFPENMTRNMNSTFGLIYSQRVMLKLIEKGMTREEAYDLVQPKTAYSWDNQVDFKPI
                     LEADENITAKLRQDELDELFNPAYYTKRVDAIFDRLGL"
BASE COUNT         6080 a         4016 c         5303 g         6371 t
ORIGIN      
        1 gtaacattaa acgcttgatt ttttgataga atataatgtg tcttatcgaa aaggagtaat
       61 ttttttagta tgaaaaaaag aattctatca gcggttcttg taagcggtgt gacccttgga
      121 acagcaacta cagtgggagc ggatgattta gattccaaaa tagcgttgca aaattcagtt
      181 atttctaatt taaataaaga acaaaaagct gcgcaggata gaatgaagac tttgcaaagt
      241 caggttagct cattacaatc tgaacaagaa aggttagtcg ctaaaaatgg tgagcttgaa
      301 gcgcgatctg ctcagtttga gcaggagatt caagtgcttg ccagtcaaat tattgctcgt
      361 aatgaaaagt taaaaggaca ggctcgtagt gctcaaaagg gaaatacgtt aggttacctc
      421 aatgcacttt tgaattctaa gtcaatttct gacgttatta ctcgtttggt tgctattaat
      481 agagctgtgt cagccaatgc acagatgttg gaaaagcaaa aggctgataa gctttctctt
      541 gaagaaaagc aacaggaaaa tcaagaagcg attaatacaa ttgcttcaaa tattacagca
      601 attgaatcaa accaagtagc tttaaagact caacaagcag atttagaggt tgccaaggta
      661 gatttggcgc ttcaattagc aactgctgag gacgagaagg ctagcttgat tacccgtaaa
      721 gaggctgcag agcaggcagc agctcaagcc aaggctcagg cagagcagga agcagcagcc
      781 agagcagcac aggctcaagc tcaagcacag tctgtagcgg cagctcaagc agcagtgact
      841 caagccgtac caacaccagc tccagcgcag gcacagcctg ttgtggcgcc agcagctatg
      901 gtttcaacac cagcggtgtc gtatgcctat gatccttcta atccgtaccc tgtcggccaa
      961 tgtacttggg gagttaaggc tttagctcct tgggttggca attattgggg aaatggtggt
     1021 caatgggcat caagtgcagc ggcagcaggt ttccgtgtag gtgcaacacc aatggttggc
     1081 tctgttgttg tatggaatga tggtggctat ggtcacgttg cctacgtaac aggtgttcag
     1141 ggtggacaga ttcaagttat ggaagccaac tatgctggaa atcaatctat tggcaattat
     1201 cgtggttggt ttagcccagg tgctgtatcg tatatttatc caaattagaa aataagtaaa
     1261 ggtaagaatc aggattctta cctttttatt tccattgaaa aattgattga aaagggttaa
     1321 aatggtatag gatcaaaact ttggaggaaa aaatgtctta ttctgattta aagctgtttg
     1381 cattatcgtc aaacaaggaa ttagcagaaa aagttgctgc tgcgatggga attcaacttg
     1441 ggaagtctac ggttcgccag ttttcagatg gtgagattca ggtcaatatt gaggaatcaa
     1501 tacgtggaca ccatgttttt attttgcagt caacaagctc gcctgttaat gataacctaa
     1561 tggaaatttt aattatggtt gatgctttaa agcgtgccag tgctgagaaa atttctgtgg
     1621 taatgcctta ttatggctat gctcgtcagg atcgtaaggc tcgttcgcgt gagcctatta
     1681 cctctaaatt agtcgctaat atgctagagg tggcaggtgt tgatcgttta ttgactgttg
     1741 atttacatgc tgcgcagatt caaggcttct ttgatattcc tgttgatcat ctcatgggag
     1801 cacctttaat tgctgattat tttgatcgtc atggtctagt aggtgatgac gttgttgttg
     1861 ttagcccaga tcatggtggt gtgacgcgtg ctcgtaagct ggcacaattc ctccaaacgc
     1921 caattgctat tattgataag cgtcgtagtg ttgataaaat gaataccagt gaggtgatga
     1981 atatcattgg tagtgttgaa ggtaaaaaat gtattctgat tgatgatatg attgatactg
     2041 ctggtaccat ctgtcatgcc gctgatgcgc ttgctgaagc aggagcaaca gcagtttacg
     2101 catcatgtac tcacccagtg ctgtcaggac cagctcttga taatattcaa aaatcagcga
     2161 ttgaaaaatt gattgttttg gatacgatct atttaccaga agaaagactg attgataaga
     2221 ttgaacaaat ctctattgca gatttgattg cggaagctat cattcgtatc catgaaaaac
     2281 gtccattgtc acccctattt gaattaggga aatgataagg ttagcctgag gtagtaagcc
     2341 ttaggctttt ttatgtttta aaaggctatt tgattaccaa agcagtgttt gatttaacgc
     2401 catagatagg cttcactgtc ttatggtagg tgttgagcta ttatagcaaa aagtcatgtg
     2461 taggtgctgt gtttaaacag ctagcctatg attcatatag ttatggctag tgactgttga
     2521 gcttcttatt ctcagagttg ttacgagcct taagtacagt gttagtcatg caattttcct
     2581 ggattttggg tataatatag ctgtatttaa ggtgttttaa aggtctagta agaaaggcat
     2641 tattactagc tgagaagctt ggttatggag atatatgcgt attcagaggt cacttggtat
     2701 tgtcttgtac aataaaaact atcgtgaaga tgataagctc gtaaaaatat ttacagaagc
     2761 ggcgggcaag cgtatgtttt tcgtgaaaca tattggtcgt tctaaactag ctcctgtggt
     2821 ccagccttta acggctgctg attttctatt gaaaatcaat gattcgagcc tttcttatat
     2881 agaggattat aatcaggtgg aggcttatcg gcacatcaat gaagattttt ttaggctatc
     2941 ctatgctagt tatgtcttgg ctctggctga tgcggctatt ccagataatg agcctgatcc
     3001 tcagttgttt gcttttttga aaaagactct tgatctgatg gaagaagggc tagattatga
     3061 cattttaacg aatatctttg aagtccagat tttggatcgt tttggggtga gaatgaattt
     3121 tcatgattgt gttttttgtc acagaaccaa tctgcctttt gatttttctc ataagtattc
     3181 aggtgtcctt tgtccgcagc attaccatga ggatgagagg cgatatggct tggatcccaa
     3241 tgtgatttat ttgcttaatc gttttcaaac gcttaatatt gatgagctaa agactatttc
     3301 tgtgaatact ggtatgaaaa aaaagcttcg tctttttatt gatgccttgt atgaggatta
     3361 tgtcggtatt cgtctaaaaa gtaaggtttt tattgatgat ttggctaagt ggggagatat
     3421 tatgaaaaac aagcagggct tgtgagctat tcaggtgtgg atttgtcctt ttatgggaat
     3481 tgtctgggga atatgctata atagttacgt tattctctag gatatttttc gttaagaaaa
     3541 ataggattaa aggagcaaaa atgaagaaaa ttgcaataga cgctatgggt ggtgattatg
     3601 cccctaaagc tattgttgag ggtgttaatc aggcgataga atccttttca gatattgaaa
     3661 ttcagcttta tggcgatcaa tcaaggattg agtcttacct agttaaatca gatcgtgtgt
     3721 ccattgttca tacagatgaa aaaattaatt ctgatgatga gccagcaaag gctattcgtc
     3781 gtaagaagaa tgcttctatg gttttagctg caagggcagt taaggatggt cgggctgatg
     3841 cagttctttc ggcaggtaat acaggcgcct tgttagctgc tggtttgttt attattggtc
     3901 gtatcaaggg agtggatcgt cctggtttgc tgtcaactct gccaacggtt gatggttcag
     3961 gctttgacat gttagatttg ggtgccaatg ctgaaaacac agcagagcat ttacaccaat
     4021 atgctatttt aggctctttt tatgcaaaac atgtgcgtgg tattgccaag cctcggattg
     4081 gcttgcttaa taatggtact gaggcaacta agggtgattc tcttcgcaag gaggtctata
     4141 attttttagc ttcagacagc agcctacagt ttattgggaa tgttgaggca agagatttga
     4201 tgtctggcgt ggcagatgtt gtggtagcag atggctttac aggaaatgct gttttgaagt
     4261 cgattgaagg cactgctatg agtattatgg gacaattgaa atcagctata gcagtaggtg
     4321 gtgttaaggc aaagtttgga gctcttttat tgaagagtag cctttatgac ttaaaggata
     4381 ctttagatta ttccagtgcg ggtggggctg tattgtttgg tcttaaagca cctcttgtga
     4441 aatcacatgg ttctagtgat gccaaggcta tttttcatac cattaagcag gttcgtacga
     4501 tgctagaaac agatgtagtt ggccaattag ttgaggagtt ttctaaggag agtgatgtaa
     4561 atgactgagg aagttatttt agagaaaatc atcgcattaa tcaagaagca aagaagtcgt
     4621 atagactttg acattacaga aaaaacagca ctaaaggatg atttaggagt agattcgatt
     4681 gaactggtag agtttgttat taatatcgaa gatgaatttg gtattgatat tcctgatgaa
     4741 gatgttgatg gcatggtatc tatgggagat atgctaaatt atttggtcaa gcgtttaaac
     4801 caaagctaaa tagttttaaa agagcaccag ctcttttttt gtttccgaaa aaacgaacat
     4861 tataagttta ttttatatta aatgtaaata aatgttgaat atttagtatg tttgtggtat
     4921 tgtttagata ttaaatgcaa agaaaggcga acaaataagt gtctaatcaa ctcatttatt
     4981 caggtaaggc aaaggatatc tatgaaacag ccgatgacgg gattgtctta atctcctaca
     5041 aggatcaggt cactatgcta aatggagcac ataaggaaat gattgaagga aaagggagcc
     5101 ttaataatca gatttctgcc ttaatctttg ataggctaaa tagggttggc gtatcaactc
     5161 attttattaa gcaattatcc gagacagaac agttaaataa aagggttgcg attattcctt
     5221 tggaggttgt tttacgaaac gtggccgctg gctcattttc aaagcgcttt ggtgttaaag
     5281 aaggtcaggc tttggacgag ccaattattg agctttatta caagaatgac gctttagatg
     5341 atcctttcat taatgatgag catgtcagct ttttaaagct tgcgactgat gagcagatag
     5401 cctacatcaa acaagagacg catcgtatta atgcttattt gaaggagtgg tttgctagtg
     5461 ttgggttgac actggttgat tttaagctag aatttggctt tgataaggag gggatgctta
     5521 tccttgctga tgagttttct ccggataatt gccgcttgtg ggataatgcg ggccgtcaca
     5581 tggataagga cgtttttcgt cgtcagcttg gcagtttgac gcaagcctat gagactgttt
     5641 tagaaaggct aagagcattg gatcaataaa gaccagctta tttgttgtca gttaagaaag
     5701 ggagctcttt tttgtccgtc atgtaagaaa ataaatcagt tcagactatt tgagctgctg
     5761 tctaagaaag gctgtctgct attggagaaa agagtcaggc tagttcttat tttgggctgg
     5821 tttctgattg gacttggtat attaactatg aataaacgta tttttgttga aaagaaggct
     5881 gattttcaga ttaaggcaca ggtcctgtta aaggaattga aacatcagct gcagttaaag
     5941 acactggttg atttgcgtat tgtgcaggtt tatgatgtgt ttcatttgga tcaggagctg
     6001 cttttaacag ctataaagca tgttttctct gagcaggtca ctgatcaggt attgtcagaa
     6061 gaagctttac aagcagattt aaaaaggtat gccttttttg cgattgaagc tctgcctgga
     6121 cagtttgatc agcgtgcggc aagctctcag gaagccttat tgttgttagg agcctcaact
     6181 gatgtgactg ttttgacctc acagctttat ttggtcaatc aagacattgc tgctgaagaa
     6241 ttagaagcct taaagcagta cttgttaaat ccagtggatt ctaggtttaa ggacatatta
     6301 gccggtcttg atgatcagga tttttcagta gcagataaag tgattccaac gcttgatgtt
     6361 tttaatgatt atacagcgga aaatcttgct cgttacaggt ctgagcaggg cctagcaatg
     6421 gaagtggagg atctgctgtt tattcaggat tatttcaaga caaaggggcg agtgccaaca
     6481 gagactgaac taagggtttt ggatacgtat tggtctgatc attgtcgtca cacaaccttt
     6541 gaaacagagc taaaaacgct tgatttttca gcttctcatt ttgaaaagca gctccaagct
     6601 acctatgaga cctaccttgc tatgcgtgat gagctaggtc gatctgaaag gcctcaaacg
     6661 cttatggata tggctaccat ttttggacgt tatgaaagag ctaatggtcg tttagaggat
     6721 ttggaggttt cagatgaaat caatgcttac tcagtggaaa ttgaggtaga tgttgatggt
     6781 gtcaaggagc cttggctgct catgtttaaa aatgaaacac ataatcaccc aacggaaatt
     6841 gaaccctttg ggggtgctgc aacctgtatt ggtggagcta ttcgtgatcc tctgtcaggc
     6901 cgttcctatg tttatcaagc catgcggctt tctggtgcag gggacattac aagcccgctg
     6961 tcagagactc gtaagggcaa attaccacag caggttattt cgaggcaagc agcacatggt
     7021 tactcgtcat atggcaatca aattgggcta gcgactactt atgttcgtga gtattttcac
     7081 ccaggctttg ttgccaaacg tatggagctt ggtgcggtag ttggtgctgc acccaaggaa
     7141 aatgtggttc gtgaaaagcc aaggacaggt gacgtggtgg ttttgcttgg tgggaaaaca
     7201 ggacgtgatg gtattggtgg tgcgacagga tcatctaagg ttcagacagt tgagtctgta
     7261 gaaacagctg gtgcagaggt ccaaaaagga aatgccattg aggagcgtaa aatccaacgt
     7321 ctttttcgtc gtggcgatgt gacacgcctc atcaagaagt caaatgattt tggtgctggt
     7381 ggtgtttgtg tagccattgg cgagcttgct gctggtctta acattaactt agataagatt
     7441 cctttaaaat atgctgggct aaatggaaca gaaattgcca tttcagaatc ccaagagcgt
     7501 atggctgtcg tgatttgtcc aaaggattta gaggccttta tgagcgcctg ccataaggaa
     7561 aatatccatg ctgctgttgt ggcagctgtg acagaaaaac cgaatcttgt tatgacctgg
     7621 aatgggcaga cgattgttga tattgaacgc tcatttttag agacaaatgg tgtgcgcgtg
     7681 tctgttgctg ctaaggttgt tgacagtggt gcgccaatac cagaagctcg tcaaactact
     7741 gctgagacac ttgaagcaga taccattgct gtcttatcag acctgaacca tgctagtcaa
     7801 aagggtttgc aaaccctgtt tgatagctca gtgggtcgct ctacagtaat acatccgctt
     7861 ggtgggcgct atcaaatgac acctgttgaa ggctctgttc agaaattacc agttcaacat
     7921 ggagtgacaa agacagtctc tgttatcgct caaggctatc acccttatat agccgaatgg
     7981 tcaccttatc atggtgctgc ttatgctgta attgaggcaa ctgctcgtct ggtcgcaacg
     8041 ggtagccatt ggcataaggc acgcttttca tatcaggaat atttccaaag aatggataag
     8101 caggcagagc gctttggtca accggtggca gccttgcttg gagcaattga agcacaggtg
     8161 cagcttggct tgccttctat tggaggtaag gattcaatgt ctggtagctt tgaggaattg
     8221 acagtgccgc cgaccttggt tgcctttggt gtgacgactg ctcatgtaga tcatatcctt
     8281 tcaccagaat ttaaagctgc tggcgagaat atttactata ttccaggaca ggctatttcg
     8341 gaagtgattg attttgagtt gataaaatct aattttatga cttttgaggc tattcagaaa
     8401 aagcataata ttagctcagc ttcggctgtt aaatatggtg gtgttgttga agcactggct
     8461 cttgctgcct ttggtaatcg gttaggggct tgtgtgacat taccagagct tgacaggagc
     8521 ttaacagctc agcttggtgg ctttatcttt acatcaaaag aggaaatcac aggtgttatc
     8581 aagcttggtc aaactaccag tgactttaca ttggttgtca atgatgtcaa gctatctgga
     8641 gctcgtctct taaaggcttt tgaagggagc ctggagcagg tttacccgac ggtatttcag
     8701 caggcaggtg aattgaagcc tgttcctgta gtgacaacag cacttgctgc tcagtttaag
     8761 gaaaaaatag ctcagccagt tgtctatatt ccagtttttc caggaactaa ctcagaatat
     8821 gattcggcta aggcctttga aagagagggt gcaagggtga acttggtgcc ttttgttacc
     8881 ttgaatgagg cagctattga cgcttcagtt gacacgatgg ttgaccatat tcatcaagct
     8941 catattatct tccttgcagg tggtttttca gcggcagatg agccagatgg ttcagctaaa
     9001 tttattgtta atatcctgct gaatgagaag gttcgaatgg cgattgatgc ctttattgaa
     9061 aagggtggtc tgattatcgg tatttgtaat ggctttcaag ctctggtcaa atcagggctg
     9121 ctgccatatg gacgttttga ggcggtacat gaggctagtc caactctgtt ttataatgat
     9181 gccaatcagc atgtggctaa aatggtagaa acgcgtattg ccaataccaa ttctccttgg
     9241 ctggcaggtg tcagggtggg ggatattcat gctgttgcag tgtcacatgg agagggcaag
     9301 cttgtggtaa cagaaagaga attagcagag ctttgtaaaa atggtcagat ttttagccag
     9361 tatgttgacc ttgatggtaa tccaagcatg gatagcaggt ataatccaaa tggctctgtc
     9421 aacgctattg aaggtcttac cagcaaaaat ggtcagatta tcggtaagat gggacattca
     9481 gagcgctttg aagagggact tttccaaaat attccgggta ataaggatca atggttattc
     9541 cgaagtgcgg tgcattattt tagaggagac catgtgggta ttgactgaac tgggatatag
     9601 ccttgtaata gctaagatag ctgctattat tgctcagcct agctgttagt tctagcttag
     9661 ttaatgacac aatcataatt aaaagggcat tagcccagag gtaaagatga catatgacgt
     9721 aaaatctctt aatgaggaat gtggtgtttt tgggatttgg ggacacccac atgccgctca
     9781 agtgacttat tttgggcttc atagcctaca gcaccgcggc caagagggag caggtattat
     9841 ttcaaatgat aatggggagc ttcatcagca tcgtgatgta ggtctcttgt cagaggtgtt
     9901 taaggattca tctgatctgg acaagctaaa gggacatgct gccattggtc atgtgcggta
     9961 tgcgactgct gggacggctt ccattaataa tattcagccc tttttatatc gttttacaga
    10021 cgctcaattt ggcttgtgcc acaatggtaa tttgaccaat gctatgtcat tgaaaaaagc
    10081 gttagagagt gagggagcta tttttaatgc ctcttctgat acagaaattc taatgcattt
    10141 gattcgtcgt agtcatcacc cagaattttt aggaaaggta aaagaggcac tcaacactgt
    10201 taaagggggc tttgcttacc tgctgatgac agagaaccag ctgatagcag cgcttgatcc
    10261 aaacggcttt aggccgttgt ctataggccg tatgaaaaat ggggcttggg tcgtctcaag
    10321 tgagacctgt gcctttgaag tggttggtgc tgagtgggtt cgcgatgtga tgccaggtga
    10381 ggtcattatc attgatgatc aggggatcac ttatgactgc tatacgacta ctacgcagct
    10441 ggctatctgc tctatggaat atatttactt tgcgcgtcct gattcaacca ttgctggagt
    10501 caatgttcac accgctcgca agcgaatggg aaagagactg gctcaggaat ttcagcatga
    10561 ggctgatatt gtggttggtg tgccaaattc ctcattatca gcagcgatgg gctttgcaga
    10621 agcatcaggc ctgccaaatg aaatgggatt ggtcaagaat caatataccc aacgaacctt
    10681 tatccaacca actcaggagc ttcgtgagca gggagttcga atgaaacttt cagctgtttc
    10741 aggtgttgtc aagggcaaaa gggttgtgat ggtagatgat tctattgtca gagggacaac
    10801 ctcacgacgc attgttaatt tgctgcgtga agcaggagct acagaggttc atgtagcaat
    10861 tggtagccct gagctcaaat acccttgctt ttatgggatt gatattcaga caagacggga
    10921 gctgatttca gctaatcata ctgctgctga ggtctgtgat attatcggtg ctgatagcct
    10981 gacttatttg tcacttgatg ggcttatcga ggctattgga cttgatacaa aagcaccaaa
    11041 tggtgggctt tgtgtggctt attttgacgg tcagtatcca acgccgcttt atgattatga
    11101 ggaggcttat ctcaagagct tagaagaaaa ggtaagcttt cacattgatc aggtgacgaa
    11161 gtagcgcttt atggctaaca tagaataaat gatctaggca gctaaaataa ggaggagaaa
    11221 atgtctaaaa atgcttatgc tcaatcaggt gtcgatgttg aagcaggcta tgagcttgtt
    11281 gagcgaataa aaaagcatgc cgagcgtagc aaacgattgg gtgttatggg tggtctagga
    11341 ggctttggtg gtctgtttga cctgtcaaag actggtgtta aggagcctgt tttggtttca
    11401 gggacagatg gcgtcggaac aaagctaatg cttgcaatcc agtacgataa gcatgacacg
    11461 attgggcagg attgtgtggc aatgtgtgtc aatgatatta ttgcagcagg tgccgaaccc
    11521 ctgtattttc ttgattacct tgcagcagga aaaaatgagc ctgccaaatt agagcaggtg
    11581 attgcaggta ttgctgaggg ctgtgttcaa gcaggtgctg ctcttatcgg tggagaaact
    11641 gctgagatgc ctggtatgta tggtcaagat gactatgatc ttgccggttt tgcggttggt
    11701 attgctgaga aatctcagct gattgatggt tcaagagtag ctgagggaga tcatctccta
    11761 ggtttggcat caagtggagt tcattcaaat ggttattcct tggttcgtcg tatttttgcc
    11821 ggttatactg gtgaggagct gcttccagag cttgatggaa aaaagcttaa ggaggtactt
    11881 cttgagccaa ctcgtattta tgtcaaggct gtgttaccac tcattaaaag cggcttagtg
    11941 gcaggaatcg ctcatattac gggtggcggc tttattgaaa acctacctcg tatgttttcc
    12001 aaagaactag ccgctgaaat tgaagaagcc agcttacctg tgctgcccat ttttaaagtc
    12061 cttgagacat atggtaagat caatcatgaa gaaatgtttg agatttttaa tatgggtatt
    12121 ggcatggtgc ttgctgtcaa gcctgagcac gttgagcagg tgaaggcctg tcttgatgag
    12181 cctgtgtatg acattggtcg cgttgtgacc agaacagttg ctagtgtggt gatgaagcca
    12241 tgacaagaat tgccgttttt gcttctggta atggctccaa ttttcaaacg attgcagaac
    12301 agtttccggt tgcctttgtt ttttctgatc attgcgatgc tcatgtttta agtagagcct
    12361 gtgctttggg tgttctgtcc tacagctttg aactaaagga ctttgagaat aagcaagcct
    12421 atgagcagac tcttgtggca ttgctgcagc ggcatcagat tgatctcatc gtccttgccg
    12481 gctatatgaa aattgtgagt acaaccttac ttgatgctta cgaaggaaaa atcatcaaca
    12541 ttcacccagc ttatttgcca gaatttccag gagcacatgg tattttagat gcttggcaag
    12601 caggtgttag tcagtcagga gtgactgttc attgggttga tagtggtatt gatacaggaa
    12661 aaatcatcaa acaggtacga gtaccacgtt tgagtgatga tactcttgaa agctttgaag
    12721 ccagaattca tgaagcagaa taccaattgt atccagaggt actggatagt cttggagtag
    12781 agcggcttaa ccgctgattg tgtaagatta ataactattt tccctattgt ggcatttcgt
    12841 ttatcatagc agctgcgcta atggtggcta acaaaggcta gaagacttgt ttgatgatgg
    12901 cactgctatt gaggaaaata gacttttcta aggagaactt aaaatgacta aacgcgcctt
    12961 aattagcgta tcagataaaa gagggattgt ggaccttgct agggagctta agcatcttgg
    13021 ctgggatatt atatcaacag gaggaacaag gcttgctctt gaagaggctg gtgtagttac
    13081 tgttgctatt gacgatgtga caggctttcc tgaaatgatg gacggacggg taaaaacgct
    13141 gcaccctctc attcatggtg gcttacttgc tcgtcgtgac attgagcacc acttacaggc
    13201 agcaaagcaa aacaggattg aattaataga ccttgttgtt gttaaccttt atcccttcaa
    13261 agaaaccatt tgccgtccag atgtcactta tgatgtcgct gttgatatgg ttgatattgg
    13321 tggtccttca ctgctgcgtt cagcggctaa aaatcatgct agtgttacgg tagtggttga
    13381 tccgacagat tatccgctcg ttttaggaga gttggctagc actggcagta caagttacca
    13441 aacccgtcaa agcttagcag ctaaagcttt tcgccatact gcagcctatg atgcagtgat
    13501 tgcagattat tttacaagac aagcaggtga gacaaagcct gaaaagctca cgcttaccta
    13561 tgatttgaag caaagcatgc gttacggtga aaatcctcaa caggctgcag atttttacca
    13621 aagagcgctc ccaacaacct attcaattgc ttcagccaag cagctaaatg gaaaagagct
    13681 atcattcaac aatattcgtg atgcagatgc tgcgattcgt attattcgtg attttaagga
    13741 gcgtccaacc gttgtagcac tcaagcatat gaatccatgt ggtattggtc aggcagatga
    13801 tattgagaca gcttgggatt ttgcttatgc agctgatccg gtgtctatct ttggtggtat
    13861 tgttgtccta aatcgtgagg tggatctagc gacagcggag aagcttcatg ctatttttct
    13921 tgaattgatc attgcaccag gctattccaa agaagcgcta gctgttctca cccataaaaa
    13981 gaagcacttg cgaattcttg aattgccatt tgctgctcag gaggctagtg aaatagaagc
    14041 agaatataca ggagttcttg gtggtctact agtgcaaaat caagatgttg tcacagagtc
    14101 tccagcggat tggatagtgg tgacaaagcg tcagccaaat gaacaggaaa tggctgctct
    14161 agcatttgct tggaaaacca tcaaatatgt caagtctaat gcgattgtca ttgctaatga
    14221 tcatatgact ttgggcgttg gtccagggca aacaaaccga atagcctcta ttcgtattgc
    14281 tattgcgcaa gcaacggggc agcttgaggg agcagttctt gctagcgatg ccttcttccc
    14341 atttgcagac agcattgaag aaattgctgc cgctggtatc aaggctatta tccagcctgg
    14401 aggctctatt cgtgattcag aatctattgc agctgccaat cagcatggta taaccatgat
    14461 tttcacaggt gtgaggcatt ttagacatta ataaagtaaa aagagactgg agccaaaaga
    14521 gttgcacttt agaaattctt ggttaatata ctttattacc tagttggatt cattaaaaag
    14581 cgaacaagtc tagttttcat aatctcagaa aactagactt gtttgcttgt tttatttggt
    14641 ggtcatacta ttgtttcagc ctctttttac tatgactaat acaagaattt atgaaggaac
    14701 aaggctttat tttttgttgt ggtaacagtg accagatccg ttatcaatca gtatttgagt
    14761 attttgagct ctagatgcat cacttagata ggatattgca aaggatacag ctgctgcatg
    14821 tattaggaaa gcattatcat aaaaggcttt ttcgttagcc taaaggtttt agaccttctt
    14881 tgccttatct attgttaacc atgttccacg tgaacccatt tgcacgtaaa tccccttgct
    14941 aggctgatca acctttagaa ccttataggt tcctgaaacg acaaaataat cacccacctg
    15001 caaaatctga tttccagcaa tacgtccttt atggtccgtt tcgtggagtg gagctgagtc
    15061 tatccagttt aaggaggttg gctctccacc ggctaattca ctgcttgcaa tcatgttctg
    15121 agcgacctga tcgacccgaa aaacaccagg aaaggctaca gtatctccaa ccttgatagg
    15181 agtggtcgcc acaggctttg gtttatctat agaggcttga ctatgttgct gaggctgaac
    15241 cggcaatttg tgaattggaa tgtagcgatg atttcctgaa tgaccgatat agctgagcca
    15301 ttcatagcca tcagcgacaa gggtttgatc atagtgcact aactgtccag tatgatagta
    15361 agctaaatca ggacttgcta atgtagcttc agcctttata ggactttggc ttgaaaaata
    15421 ataggtacca cttttagcta gacgagttga tcctgcttga gaagcatgta acatttgtgt
    15481 gtggctggta gagttgtgat ccagatcctt gaagtgaatg taaccactta cctgatgctt
    15541 atgaatctgt cgtttatgat acttttcagg tccctgtccg gcattatagt tgtattcctc
    15601 aataataaca gtgtcaccat tgacctctgc tacccaggcg acgtgtccat atagggcatg
    15661 tgactggtta aagcccttat cccaccaagc aacagcacca actctaggtg tatgatcaac
    15721 atgatagcct tggtgtttag ctatacgtcc ccagctttca acattaccat agcctctagg
    15781 caggctgaat ccatttgagg aatgcagtcg gaatgctaca aaagaagtgc attgacgtaa
    15841 gtacatgttc caaggatcag ctccgaagcc ctgtttccac ttacttggat agttatcccc
    15901 taaaacagca gcgtgtacga tacctgactg accttgtgaa atcgttgttg tggcagagga
    15961 tattgcacca ttaccaccta aaaggattgc tcctgaagct aacaattgat agactttttt
    16021 cattaattac ctcctgtaac ttactattcg caagaaagag gacaaaaatg tccttgattt
    16081 aaaaaaatgt aaggaaaaat attttagcct caaaatactg ttggtgctcc ctagcttcca
    16141 agagccaata ggcaagccca tctccagctt gcctgctccc tgtagctaaa agcaatttat
    16201 agtaacacta gcacctcatc tgaagaggca ggctgtggta attaatgcca ataatctgta
    16261 aaaagagaca gcaggtatgg ttatatgagc tatgatggtt atattctata aagcttattt
    16321 tttagcttcg ggctttcttt ggtgattagt tatttatata aacgaacaat tatgctaaaa
    16381 tatgtttata aaattcgtgt tatgaggtgt gtgatgaagc ttttagttat cggttcaggt
    16441 ggtcgtgaac atgcgattgc taagaaattg ttagagtcaa aaggcgttga acaggttttt
    16501 gtggcacctg gcaatgatgg catgaccctt gatggcatag aacgggtaga tattgatatt
    16561 tccgaacatt ctgctttgat tgcttttgca aagaccaatc atatagcctg gacctttgtg
    16621 ggaccagatg acgcattagc ggctggtatc gttgatgagt ttaaccagtc tggcttgaaa
    16681 gcctttgggc cctctcgttt agcagcggag ctggagtggt caaaggactt tgctaagcaa
    16741 atcatggtca aatacggtat tccaacagca gcctatggca cattttctga ttttgcaaaa
    16801 gccaaggcct acatcgagga aaagggcgcg ccaattgtgg ttaaagcaga tggtttggcg
    16861 ctaggaaagg gtgttgtcgt agcagagact gtagagcagg cagttgaggc ggcgcgtgac
    16921 atgctcttgg ataataaatt tggtgattca ggtgcgcgcg tggtgattga ggaattttta
    16981 gctggtgaag agttctctct ctttgccttt gtgaatggcg atcagtttta cctcatgccg
    17041 acagcgcagg accacaagcg ggctcttgat ggtgacaagg ggccaaatac aggtggtatg
    17101 ggggcttatg caccagtgcc tcatctttct caaagtgtgg tggatacagc agttgagacc
    17161 attgtcaagc ctgttctaaa agggatgatg acagaggggc gtccctatct tggaatcctt
    17221 tactgtggct tgattttgac agaagatgga ccaaaagtga ttgaattcaa tgctcgcttt
    17281 ggtgatcctg agactcaggt tatccttcct cgcctgacct ctgattttgc acagaacatt
    17341 accgatatat tagagggcaa cacagctaat atcacatggt cagacgaggg agtgacgctc
    17401 ggcgttgtcc ttgcttcaaa cggttatccg cttgcttaca agaaaggtgt gcttctgcca
    17461 gcaaagacca ctggcgacat cattacctac tacgcagggg ttaagcttgc ggaaaatggc
    17521 aaagcactgc tgtcaaatgg tggacgtgtc tatatgctgg tcaccacagc agttaccgtc
    17581 ccagctgcgc aagaaaaaat ctataccgaa cttgctcagc aaaataccga aggattattc
    17641 taccgaaacg atattggaag aaaagcagta aaataaatta gcgctagctc aagctaccga
    17701 aggtcgctat gatgacaatg acttattatc ggtgagcaaa agcgagccta acacgatact
    17761 tttcgccgta gcgcaaagag tgacaaggtc actcggggga acttgaaaga ccttgggctt
    17821 tcaagttagt catgagacac ctatggtggc tgttgacgcc cccccccact taagaaaagt
    17881 atcaaaaacc tttaaggaga aagtatgaaa ccaattatct ctatcatcat gggctccaaa
    17941 tctgactgga ccaccatgca aaaaaccgcc gaaatcctcg accagtttgg ccttgcctac
    18001 gaaaaaaaag tggtctctgc ccaccgcacg ccggatctca tgttcacata cgctgagaaa
    18061 gcacgcgaac gtggcattaa aatcatcatc gctggtgctg gcggagcagc ccatctccct
    18121 ggaatggtcg ctgcaaagac gacacttcct gttatcggcg tacctgtcaa atcgcgtgct
    18181 cttagtggtc ttgattcgct gtattcaatt gtgcagatgc caggtggtgt gcctgtggca
    18241 actatggcca ttggagaggc aggagcaacc aatgcagcac tgactgctct tcggatcctt
    18301 tcaattgagg atgaaacaat cgcagagcag ctcagccatt tccacaaaga gcaaggacgg
    18361 atcgcagagg agtcaaccca tgaactcaac taaaacaatt ggaattatcg gaggtggtca
    18421 gctgggacag atgatggcga tttctgccat ttatatgggg cataaggtca ttacactgga
    18481 tccagcagcg gattgcccag cctcgcgcgt gagtgaggtt atcgtggcgc cttatagtga
    18541 tgtggaggcg ctgcgtcaat tgaccgagcg ctgtgatatt ttgacctatg aatttgaaaa
    18601 tgtggacgct gacgcccttg atacagtggt aaaggaggag cagctgcctc aaggaacaga
    18661 gttacttcgg atctcgcaga atcgtatttt tgaaaaagat tttttagcca ataaagcaag
    18721 cgcggcagtg gcaccctaca aggttgtaac ctctagcctc gacttggaaa accttgactt
    18781 ttcgaaaaaa tacgtcctca agacagcgac aggtggctat gatggacacg gtcaagtcgt
    18841 tattcgctcc gaagcagacc ttgaagaggc taataagttg gctaacactg ccgagtgcgt
    18901 cttggaagaa tttgtcagct ttgaccgaga gatttccgtt attgtatctg gcaatggcac
    18961 agatgtcact gtctttcctg ttcaggaaaa tatccatcgg aacaatatcc tgtcaaaaac
    19021 cattgtccca gctcgcattt cagaagcagt tagcgctaaa tcgcaggcta tggcggtgaa
    19081 aatagcagag cagcttaacc tatctggcac cctctgtgta gaaatgtttg tggcaggcga
    19141 cgagattttg gtcaatgaaa tcgccccacg tccccacaac tcaggacatt actccatcga
    19201 agcctgtgat ttctcccagt ttgacaccca cattttaggt gtattaggcc agccattacc
    19261 agctgtcaaa ctccatgccc cagccattat gctcaacgtc ctcggccagc acatggaaca
    19321 agcccaacgc tacgccacag aaaaccctag cgcccacctc cacctctatg gtaaaataga
    19381 agccaagcac aaccgcaaaa tgggacacgt gacggtgttt aacagtcaat cagatgaggt
    19441 tgaagaattt taggaggaat taatcctatg ataaaaatca ttgttcacgc ttttattgaa
    19501 aatggtgaaa caggtgttgt tgaagttgtc tttgcttcgg aaaaccaaga atccatttct
    19561 gaaaaaatga cggagctaca aaagcaatat ccaaacgatt accttgctat ctatgattta
    19621 ccactagata cagacctatc gcaattggcc cactatccgt caatagcgat aggcaaaggg
    19681 gagtttgagt agttaaggaa gattagtatt tcggattgag tgttattggg acaatttatg
    19741 gctatgcctt tcaaaagatt ggtcatgatg ttgagcatgt tgtgagaatt gagaatcgta
    19801 atcagatttc agaagttggt aaatgactta atggataatt ctagatactg atctcgagca
    19861 atcataagag aaatgttgaa attgtagctt ctggaggtgt agaactcaaa aattatcgtg
    19921 gtgagatatt tccatataaa acttctaagc gtatttcgtc tagattgata acatatagat
    19981 aggtttgtac ataatgaact tactagatgc atcatgacaa agcagatctt ttatatacat
    20041 gcaaagaggt ttacaatatt ggtatagtca actattgatg ccctaacttt taatcacaat
    20101 atagaaatta ttgcgaatag actttaaaag cattactatt aactatgtag aaaggaaatg
    20161 agcgctagaa ttttcaaact gaacctgagc ggaaagctcg gaatttagat aaatttcctc
    20221 ggacgtaaat gtccgtcttt agctttctaa aattcagttg ctttctggct gttcttggta
    20281 tcttaattat gctaaaccgt tattcacgcc ctgagatggc gaagatttgg agtgaagaga
    20341 acaagtaccg tgcttggttg gaggtggaaa tcctcgctga tgaggcatgg gctgagttgg
    20401 gtgagattcc caaggaagat gtggcgaaga ttcgcgccaa tgcgagtttt gacatcaatc
    20461 gtattttgga gattgaagaa gagacccgtc acgatgtggt ggcctttact cgtgcggtgt
    20521 ctgaaacgct cggtgaggag cgcaagtggg tccactatgg cttgacatcg actgacgtgg
    20581 tggatacggc ctatggctat ctctacaagc aggctaatga cattatccgt cgtgaccttg
    20641 aaaactttac caacattgtg gctgagaagg ctaaggagca caaaatgact atcatgatgg
    20701 ggcgtactca tggtgtgcac gcggagccaa cgaccttcgg tctcaaattg gcgacctggt
    20761 acagtgaaat gaagcgtaat caagagcgtt ttgagcatgc ggctgctggt gttgaggccg
    20821 gtaaaatctc aggtgctgtt ggaaactttg ccaatatccc accatttgtt gaggagtatg
    20881 tctgtggcaa gctaggcatt cgcccgcagg aaatctcaac tcaggtcttg ccacgagacc
    20941 ttcatgccga gtacttcgca gtgcttgcta gtatcgcgac atcaattgaa cgcatggcaa
    21001 ctgaaattcg aggcctgcaa aaatctgagc aacgtgaggt agaagagttc tttgccaaag
    21061 gacaaaaggg aagctctgcc atgcctcata agcgtaaccc gatcggctct gaaaacatga
    21121 cggggcttgc gcgtgtcatt cgtgggcaca tggtgacagc ctatgagaac gtggcgcttt
    21181 ggcatgagcg tgatatttcg cactcgtcag cagagcggat tatcacacca gacacgacta
    21241 tcctcatcaa ctacatgctc aaccgttttg gcaatatcgt caaaaatttg acagtctttc
    21301 cagaaaacat gactcgtaac atgaactcta cctttggctt gatttacagc caacgtgtga
    21361 tgcttaagct gatcgaaaaa ggcatgacgc gtgaggaggc gtatgacttg gtacagccaa
    21421 agacagccta ttcatgggac aaccaagtgg acttcaagcc gatccttgag gcagacgaaa
    21481 atatcactgc aaaattaagg caagatgagc ttgatgagct cttcaatcca gcttattata
    21541 ccaagcgtgt cgatgctatt ttcgaccgat taggattata ggaagaaaac agcgcgtctt
    21601 tttagactgt agctaagccc agatttgttt aaaaagtctt gaaaatgaat tcctcggagc
    21661 taattctcaa aatgaagaat agtatttcaa gagaggctgt cactagctat atcgcttaag
    21721 aaaatgctct aaaatagaca ttttttcaat ctgagaaggc aataggcctt
//
LOCUS       DARYXW010000028        21551 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.028, whole genome shotgun sequence.
ACCESSION   DARYXW010000028 DARYXW010000000
VERSION     DARYXW010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21551)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21551)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21551
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.028"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            33..1643
                     /locus_tag="TV191_000856"
     CDS             33..1643
                     /locus_tag="TV191_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEL1507387.1"
                     /translation="MLINIITLLVCGLIGVILGYALISIRLKSAKEAAELTLLNAEQD
                     AVDIRGKAKADAAHIKKTAQRESKASRKELLLEAKEEARKYREEIEQEFKSERQELKQ
                     LETRLAERALTLDRKDENLSSKEKVLDSKEQSLTDKSKHIDERQAQVEKLEEDKRAEL
                     QRVAAMTIAEAREVILMETENKLTHEIATRIRDAERDIKDRTDKTAKDLLAQAMQRMA
                     GEYVTEQTITSVHLPDDNMKGRIIGREGRNIRTLESLTGIDVIIDDTPEVVVLSGFDP
                     IRREIARMTLESLIADGRIHPARIEELVEKNRLEMDNRIREYGEAAAYEIGAPNLHPD
                     LIKIMGRLQFRTSFGQNVLRHSVEVGKLAGILAGELGENVALARRAGFLHDMGKAIDR
                     EVEGSHVEIGMEFARKYKEHPVVVNTIASHHGDVEPDSVIAVLVAAADALSSARPGAR
                     NESVENYIKRLRDLEEIATSFDGVQSSFALQAGREIRIMVQPEKISDDEIVVLSHKVR
                     EKIENNLDYPGNIKVTVIRELRAIDYAK"
     gene            1805..2431
                     /gene="gmk"
                     /locus_tag="TV191_000857"
     CDS             1805..2431
                     /gene="gmk"
                     /locus_tag="TV191_000857"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEL1507388.1"
                     /translation="MSERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQ
                     RPGEVDGVDYFFRTREEFEELIKNGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKAKVPDGVFIFLTPPDLDELQDRLVGRGTDSQEVIAKRIERAKEEIALM
                     REYDYAVVNDEVPLAAERVKRIIETEHFRVERVIGRYDQMIKTTKSLR"
     gene            2456..2773
                     /locus_tag="TV191_000858"
     CDS             2456..2773
                     /locus_tag="TV191_000858"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000979238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEL1507389.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILQAKRAHELEAGAAPTQSFKSV
                     KSTLQALEEIESGNVVIHPDPAAKRAAVRARIEAERLAREEEERKIKEQIAKEKEEEG
                     EKI"
     gene            2837..5221
                     /locus_tag="TV191_000859"
     CDS             2837..5221
                     /locus_tag="TV191_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEL1507390.1"
                     /translation="MQHIAQVIVDIPLMQTDKPFSYLIPDELLSLVKIGSRVHVPFGN
                     GNRLLQGFVIGFSSQSTQQLKAIWSVLDAEPVLNQEQVALAEQLRQTVFSYKITLLKA
                     MLPSLLNSHYDRLLTPTADLAAADLADVFSNGDSLLYSKLSPEQEGRVLRLIQSGKIR
                     ATYLAKDKKTIKTETYYQVNRLALQEHKISNRAKKRQALKAYLLANPQKDKLAKLYQD
                     YSREVVSYFVTNQLIELEERRVNRSEDYFNHIKAAPLLKLNQQQQQAVDQITKAVGRE
                     AKPFLLEGITGSGKTEVYLHVIAHVLEQGKTAIVLVPEISLTPQMTSRFISRFGRQVA
                     IMHSGLSDGEKFDEWQKIKTGQARVVVGARSAIFSPLENIGAIIIDEEHEATYKQESN
                     PRYHARDVALIRARHHKAALVMGSATPSIDSRARASKGLYQFIQLTERANPLASMPQV
                     EIVDFRDYIGQQEVSSFTPYLIDKLKERLARKEQAVLMLNRRGYSSFIMCRDCGYVDQ
                     CPNCDISLTLHMDTKTMNCHYCGFQRAIPKLCPSCQGKSIRYYGTGTQKAYDELKQVL
                     PEARILRMDVDTTRKKGSHEAILSQFGNGDADVLLGTQMIAKGLDFPNVTLVGVLNAD
                     TSLHLPDFRASERTFQLLTQVAGRAGRADKPGEVLIQTYNPEHYAIQLAKKQDFEAFY
                     AYEMGIRRKLGYPPYYFTVGLTLSHKSEQEVVKKAYQLLTILKQGLSDQIRILGPTPK
                     PIARTHNLYHYQIILKYRFEDQLEATLNQILDWSQEQDNRELKVIIDQEPQSFM"
     gene            5288..6223
                     /locus_tag="TV191_000860"
     CDS             5288..6223
                     /locus_tag="TV191_000860"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEL1507391.1"
                     /translation="MTRLIFMGTPQFSATVLQGLLEKPAYDILAVVTQPDRAVGRKKD
                     ITMTPVKKLALAHQLPVFQPEKLSGSQELADIMALGADGIVTAAFGQFLPTVLLDSVT
                     FAVNVHASLLPKYRGGAPIHYAIINGDKEAGVTIMEMVKEMDAGDMISSASLPILDTD
                     NVGTMFDKLAILGRDLLLKTLPDYLSGDLKPVPQDHSQATFSPNLSAEEERLDWSKPA
                     REVFNHIRGMNPWPVAHTLLDGQRFKIYEAELAEGSGSAGQIIAKTKKALVVAAGEGA
                     LSLTLVQPAGKPKMPIVDFLNGIGRSLEVGDVLGE"
     gene            6213..7535
                     /gene="rsmB"
                     /locus_tag="TV191_000861"
     CDS             6213..7535
                     /gene="rsmB"
                     /locus_tag="TV191_000861"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEL1507392.1"
                     /translation="MANDWKKSARGQALLIVEDIFDHGAYSNLALKHQLANQFLSDKD
                     KALVTEIVYGTISRKITLEWYLAHYIEDRDRLDKWVYYLLMLSLYQLAYLDKVPAHAI
                     VNDAVNLAKARAHGRGADKLVNAVLRQLTNKPLPDIKSIKRKNKYYAVAYSVPVWLVK
                     KLIDQFGEERAVAIMESLFVRSRASIRVTDLTKLDEIKQATGSEQSLLARTGLTKRAG
                     NFAASSYFINGDITIQDETSQLVAPTLDIQGQEMILDACSAPGGKTAHIASYLTSGKV
                     VALDLYEHKLALVNENAKRLGVADRIETKVLDAREVHKHFAKNSFDKILVDAPCSGIG
                     LIRRKPDIKYNKEGQDFQQLQEIQLEILSSVCQTLRKGGIITYSTCTIFDEENFQVID
                     KFLQRHPNFEQVTLKHAQADIVKDGCLMITPEQYQTDGFFIGQVRRVL"
     gene            7573..8313
                     /locus_tag="TV191_000862"
     CDS             7573..8313
                     /locus_tag="TV191_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEL1507393.1"
                     /translation="MKISLKTDIGQKRSNNQDFINKFDNKKGITLVILADGMGGHRAG
                     NIASEMTVTDLGREWVKTDFTELSQIKDWLLTTIEAENQRIYDLGQSEDYKGMGTTVE
                     AVALVDSNAIYAHIGDSRIGLVHEGNYSLLTSDHSLVNALVKAGQITEEEAASHPQKN
                     IITQSIGQASPVEPDLGVKVLEKGDYLVINSDGLTNMIANEEIVDILCQDISLDEKNQ
                     ALIDLANQRGGLDNITVALVHKESGEAE"
     gene            8310..10205
                     /gene="pknB"
                     /locus_tag="TV191_000863"
     CDS             8310..10205
                     /gene="pknB"
                     /locus_tag="TV191_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEL1507394.1"
                     /translation="MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVL
                     RTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIGEEDGQQFLVMEYVDGSDLKKYI
                     QDHAPLSNNEVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKSSVVKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSIIDENPNVPQALENVVIRATAKKLSDRYRSTFEMSRDLMTALSYN
                     RSRERKVVFDDVESTKPLPKVTPTPVTAPKVSNASQASAAVDARLEQTSQMDTLQKPQ
                     KKKKNGRFLGTLLKILFSFFVVGVALFAYLVLTKPTTVKVPDVTGSSLNAAKQVLEEA
                     GLKVGKVHQIESDTVSEDQVVKTNPQAGSAKRKGSSVDLYLSIGNKGFEMENYKGQDY
                     QDVMTSLTETYGVPKSKIKIERIVTNEYPENTVISQSPSAGEKFNPAGKSKITLSVAV
                     GDTVIMPMVTEYSYADAVNTLTALGIDAARIKAYVPSSSSPTGFVQVSSPSSKAVVSG
                     QTPYYGTQISLSEKGDISLYLYPEETRASSSSSSSDTSAPNPSAGDTTDSSSHTELGQ
                     NDAVTTP"
     gene            10338..11030
                     /locus_tag="TV191_000864"
     CDS             10338..11030
                     /locus_tag="TV191_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEL1507395.1"
                     /translation="MKKFQFFLLVECMLLAMGIMTILANDLSSFILILVLILLALRFY
                     NQDTRNSFLLTVSLLLLFLIFMLNPYIIMAVLLGIVYVIINHFSQVKKKNRFALIRFA
                     EEKMTVRQVKNQWLGAANYESDYYSFEDINIIRASGNDTIDLTNVIVTGMDNVIIIRK
                     IFGNTKILVPIDVAVTLEVSSIYASVDFFELQEYDLRNESITLGEAEDSSLKKVKIIV
                     STIAGNVEVARR"
     gene            11027..12031
                     /locus_tag="TV191_000865"
     CDS             11027..12031
                     /locus_tag="TV191_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1507396.1"
                     /translation="MKKRYYALVWLYSTITILSIVFVVMDNLGITFDYLRSHLWQLER
                     LVFSVVLLIISVTLLLLLLWIILDDNSKRSINKNLRRILNNQRIHLEETSEINTNLTR
                     LSAKMSHITTNIQKKENAYILDSQKIVQQERKRIARDLHDTVSQELFASSMILSGVSM
                     SLDQMDKEQLQQQLVTVEAMLQNAQNDLRILLLHLRPTELANRSLSEGFTMILKELTD
                     KSGIEVVYKENIGTLPKAIEDNLFRIAQEFISNTLKHAKASRLEVYLNQTPTELQLKM
                     VDNGVGFDMGQVRELSYGLKNIEDRVNDLAGTLRLISQKGKGVSMDIRLPLVMGDEDE
                     "
     gene            12024..12665
                     /locus_tag="TV191_000866"
     CDS             12024..12665
                     /locus_tag="TV191_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1507397.1"
                     /translation="MSNITVILVDDHEMVRMGLKSFLNLQQDVDVIGEASNGREGVEL
                     ALELRPDVVVMDLVMPELGGVEATLEILSKWKEARVLVLTSYLDNEKIYPVIDAGAKG
                     YMLKTSSAAEILNAIRKVAKGELAIETEVDKKIKAHDQQPNLHEELTAREYDILHLLA
                     KGYDNQTIADELFISLKTVKTHVSNILAKLQVDDRTQAVVYAFRHHLVPQDDH"
     gene            12698..14098
                     /locus_tag="TV191_000867"
     CDS             12698..14098
                     /locus_tag="TV191_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL1507398.1"
                     /translation="MDAKLKYKAKKIKMVFFDIDDTLRVKNTGYMPESIQRVFKELKK
                     KGILTGIASGRARYGVPKEVQDLQADYCVKLNGAYVKDNQKNIIFQAPIPADTVVAYK
                     KWANAVGIDYGMAGRHEAVLSARNEMISDAIDKVYSTLEVCPDYNEHHDVYQMWTFED
                     KGDDLQLPVELAEQLRLVRWHDHSSDVVLKGTSKALGVSKVVEHLGLRPENILVFGDE
                     LNDLELFDYAGISIAMGVSHPQLQEKADFITKTVEENGILYALEELGLIDKELHFPQL
                     DLAGHEGPRVVMKTNHGELTLALFPEHAPKTVANFLGLAKEGYYNGVIFHRIIADFMI
                     QGGDPTGTGMGGQSIYGQSFEDEFSEELYNLRGALSMANAGPNTNGSQFFIVQNTSLP
                     YSQKELERGGWPKDIAAAYAEHGGTPYLDRRHTVFGQLADEASYQVLDNIAAVETGAQ
                     DKPKEDVVIEAIEVFD"
     gene            14098..14460
                     /locus_tag="TV191_000868"
     CDS             14098..14460
                     /locus_tag="TV191_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEL1507399.1"
                     /translation="MKIGDKLHGTITGIKPYGAFVALENGTTGLIHISEIKTGFIDNI
                     HQILRLGEAVLVQVIDYDEYSHKVSLSLRTLEEEKHHVSSHHRFSNSRYKIGFKPLEA
                     SLPNWIEEGLDHFKQEKS"
     gene            complement(14847..15773)
                     /gene="cysK"
                     /locus_tag="TV191_000869"
     CDS             complement(14847..15773)
                     /gene="cysK"
                     /locus_tag="TV191_000869"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003063544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEL1507400.1"
                     /translation="MSKLYHNITELVGKTPIIKLRNTSPEEAADIYVKLEAFNPGSSV
                     KDRIALAMIEAAEKAGMIKPGDTIVEPTSGNTGIGLSWVGAAKGYRVLIVMPETMSIE
                     RRQIIQAYGAELVLTPGSDGMKGAIAKAEEIARETGAWMPSQFDNPANPKVHEETTGQ
                     EIIAVFGEKGLDAFVSGVGTGGTISGVAHALKAVNPDISIYAVEADESAVLSGEESSP
                     HKIQGISAGFIPNTLDTKAYDHIIRVASEAALATARSIGAKEGFLVGISSGAAVYAAI
                     QAAKELGKGKKVLAILPDNGERYLSTALYQFD"
     gene            complement(15894..16535)
                     /locus_tag="TV191_000870"
     CDS             complement(15894..16535)
                     /locus_tag="TV191_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEL1507401.1"
                     /translation="MEDYKTIMTDGLFEESIKKSRFICQIKRVYTEEEARAFIADIKK
                     KHYKANHSCSAMIIGDKGQTKRSSDDGEPSGTAGIPMLSVLERQELTNLVAVVTRYFG
                     GVKLGAGGLIRAYSGVTAAAIQALKVVEVKKQTGLAISLTYPQYQIYPNFLEQEALIE
                     MNTEFSDVVRTAIYFDPERLESISKALIEHYHGKVSFEEIESQRIEVPVLPAN"
     gene            16591..17759
                     /locus_tag="TV191_000871"
                     /pseudo
     CDS             16591..17759
                     /locus_tag="TV191_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623352.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
     gene            complement(17789..19222)
                     /locus_tag="TV191_000872"
     CDS             complement(17789..19222)
                     /locus_tag="TV191_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014570823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEL1507402.1"
                     /translation="MITTRKVAIYVRVSTTNQAEEGYSIQGQIDSLIKYCEAMGWIIY
                     EEYTDAGFSGGKIDRPAMSKLITDAKHKRFDTILVYKLDRLSRSVRDTLYLVKDVFNQ
                     NNIHFVSLQENIDTSSAMGNLFLTLLSAIAEFEREQITERMTMGKIGRAKSGKTMAWT
                     YTPFGYDYNKEKGELILDPAKAPIVKMIYTDYLKGMSIQKIVDKLNKMDYNGKDCTWF
                     PHGVKHLLDNPVYYGMTRYNNKLFPGNHQPIITKELFDKTQRERQRRRLGIEENHYTI
                     PFQAKYMLSKFLRCRQCGSRMGLELGRPRKKEGKRSKKYYCLNSRPKRTASCDTPLYD
                     AETLEDYVLHEIAKIQKDPSIASRQKHIEDHELKYKRERIEANINKTVNQLSKLNNLY
                     LNDLITLEDLKTQTNTLIAKKRLLENELDKTCDNDDELDRQETIADFLALPDVWTMDY
                     EGQKYAVELLVQRVKVDRDNIDIHWTF"
     gene            complement(19354..19557)
                     /locus_tag="TV191_000873"
     CDS             complement(19354..19557)
                     /locus_tag="TV191_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014611912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507403.1"
                     /translation="MKWLFLILFIGCGANAVNLSKKVNSDDEVDENNSHLISHSNEEI
                     PWNKKEQLYWGTASIVFLVLFII"
     gene            complement(19560..20729)
                     /locus_tag="TV191_000874"
     CDS             complement(19560..20729)
                     /locus_tag="TV191_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HEL1507404.1"
                     /translation="MGLFNFGKIKDVALEKKLQKLQQKIENEKEKLREIKEEIALAND
                     TLDLQEYGFFERQYKFSHSTKYKDALDTLRMKQKTLIKNGEATSIISPMTLDGSAAKG
                     KAMQNQLRKAAIRGFNGEADALLVKVSVVNVDKKVQTLQKAFEQLNKMYERNLIQLTF
                     KYLDLKAQELRLAAEYELQKQEEKEILREQRAREREDKKLQAEITAKRKQLEKDRKHF
                     LQMVKNVEVMLANASPKEQEKLQLQLIEYQNKLSELDKIEEDIDYREGHATAGYVYVI
                     SNIGAFGEDVYKIGVTRRLDPMDRIRELGSASVPFTFDVHALIFSEEAFALESELHNK
                     FEAYKVNKINSRKEYFRVPFAKIKEVLENHKELAIEITEEAEAFEYRQSILKNGG"
     gene            complement(20738..21526)
                     /locus_tag="TV191_000875"
     CDS             complement(20738..21526)
                     /locus_tag="TV191_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1507405.1"
                     /translation="MARGRGRLTPQEIEALGFFSSKFNDLLNETNTKQVELSKATGIP
                     PSTLTGYVKGTSLPIPGNVQKIADYFGLMKSDIDPRFAPRKKNHELKIPTSPLVKKIT
                     TTVVELNVPRKQKVLDFATDQLKEQKNKMTSMEKKLYEYKVYEKLSAGTGYGYFGDGN
                     YDTVFYEEELDYDFASWVFGDSMEPTYLNGEVVLIKQTGFDYEGGVYAVEWDGQTYIK
                     KVYREKDGLRLVSLNKKYKDKFAPFSEDPRIIGKIVGNFMPKEY"
BASE COUNT         6229 a         4226 c         4738 g         6358 t
ORIGIN      
        1 aatgaaaact aaactattat tgaggtaaag acatgttaat taatatcata acgttacttg
       61 tctgtggcct cattggtgta atattaggtt atgcacttat ttcgattaga ctcaagtctg
      121 cgaaggaagc tgcagagttg actcttttaa acgctgaaca ggatgctgtt gatattcgtg
      181 gcaaggcaaa ggccgatgcc gctcatatca aaaagacagc acaacgtgaa agtaaagcaa
      241 gtcgtaaaga attactttta gaagcaaagg aagaggcaag aaagtatcgt gaagaaattg
      301 aacaggaatt taaatctgaa agacaagagc ttaaacagct ggagacgcgc ttggcagagc
      361 gtgctctaac tcttgatcgt aaggatgaaa atctatcaag taaagaaaaa gtactagata
      421 gcaaagagca aagtctgacc gataaatcta agcacattga tgagcgacag gcacaggttg
      481 aaaaacttga ggaagacaaa agagcagagc tccaacgagt tgctgctatg accattgcag
      541 aagcgcgtga ggttatcctg atggaaactg aaaacaagct gacgcatgag atcgcaacac
      601 gcattcgtga tgcagagcgt gacatcaagg acaggacaga caagactgct aaggacctgt
      661 tagcacaggc catgcaacgt atggctggtg agtatgtgac tgagcagacg attacaagtg
      721 tgcacttgcc tgatgataac atgaaagggc gtattatcgg tcgagagggt cgcaatatcc
      781 gtactctaga gagtctgaca gggattgatg tgatcattga cgataccccg gaagtggttg
      841 ttttatcagg ctttgaccct attcgtcgag agattgctcg tatgacccta gagtccttga
      901 ttgctgatgg tcgtattcac ccggcgcgta tcgaggaatt ggttgagaaa aatcgtcttg
      961 agatggacaa taggattcgt gagtatggtg aggctgctgc ctatgagatc ggtgcaccta
     1021 acctccaccc ggatttgatt aagatcatgg ggcgcttaca gtttcgtacc tcatttggtc
     1081 aaaatgtttt acgccactca gtcgaggttg gtaagctagc tggtatttta gctggcgagc
     1141 ttggtgaaaa tgtggcactt gcacgtcgcg caggtttctt gcatgatatg ggcaaggcta
     1201 ttgatcgtga ggttgaagga agccacgttg agattggtat ggagtttgct cgcaagtaca
     1261 aggagcaccc tgttgttgtg aacaccatag ccagccatca tggcgatgtc gagccggatt
     1321 cggttattgc agttctggta gctgctgctg atgcccttag ctctgctcgt ccaggtgccc
     1381 gcaatgaatc tgtggaaaac tatatcaagc gtcttcgtga ccttgaagaa atcgcaacaa
     1441 gctttgatgg tgttcaaagt agctttgccc tccaagccgg tcgtgagatt cgcatcatgg
     1501 ttcagccaga aaagatttct gatgacgaga ttgtggttct ctcacacaag gtaagagaaa
     1561 agattgaaaa taacttggat tacccaggaa atatcaaggt aactgttatt cgtgagttgc
     1621 gagcaataga ttatgcgaaa taaaaaggaa agagtgtatg cttttcaaaa gccagagttt
     1681 agcctctagc tttgagaagg cgtctatctc ttccttttct ttcttaggat tgggctgata
     1741 attgtcttga aaaacgatag cctttttgat aaactattag aaagcaatca ataaggagaa
     1801 cacaatgtct gaacgcggtt tgttaatcgt tttctctggc ccctcaggtg tcggaaaggg
     1861 aacggtgaga caagagattt tttcaacgcc agatcataaa tttgaatatt ctgtttcgat
     1921 gacgacacgt ccacagagac caggtgaagt tgatggggtt gattatttct tccgcacacg
     1981 agaagaattt gaagagctaa taaaaaatgg tcaaatgcta gaatatgcag agtatgtcgg
     2041 caattactat ggcactccct taacctatgt taacgaaacc cttgataagg gcattgatgt
     2101 ctttttggaa attgaggtac agggtgcttt gcaggtcaag gctaaggtgc ctgatggtgt
     2161 cttcattttt ctaacgccgc cagacttaga tgaattgcag gaccgtttgg ttggtcgtgg
     2221 aacagacagc caagaggtga ttgccaagcg tatcgaaaga gctaaggaag agattgcgct
     2281 catgcgagag tatgattatg ctgtggtcaa cgacgaggtt cctttagctg cagagcgtgt
     2341 caagcgtatt attgagaccg agcattttcg cgttgagcgt gtgattggtc gctatgatca
     2401 aatgattaaa acaacaaaat ctctcagatg atagaaatag aaaagagtaa agcccatgat
     2461 gttaaaacct tcaattgata ctttattaga taaagtccca tcaaaatatt cacttgttat
     2521 tttacaggcc aagcgtgctc atgaattaga agcaggtgct gcaccgacac agtcctttaa
     2581 gtctgtcaaa tcaacacttc aggcactaga ggagattgag tcaggcaatg ttgtgattca
     2641 cccggatcct gctgctaagc gtgcggctgt tcgtgcaagg attgaggcag agcgtttagc
     2701 aagagaagaa gaagagcgta aaataaaaga gcagattgca aaagaaaaag aagaagaggg
     2761 agaaaaaatc taaggttgag tcaatcttag tttttttcat attgcaggtc catttcttga
     2821 tagaaaggaa gtcaaaatgc aacacatagc acaggtcatt gttgatattc ccttgatgca
     2881 aaccgataag cccttttctt atcttattcc agatgagcta ttatctctgg ttaagattgg
     2941 ttctcgcgtt catgtgcctt ttggtaatgg caataggttg ctacagggct ttgttattgg
     3001 cttttctagt caatcaacgc agcaattgaa ggctatttgg tcagttttag atgctgagcc
     3061 tgttttaaat caggagcagg tggcattagc agagcaatta cgacaaacag tcttttccta
     3121 caaaatcacc ctcttaaagg caatgcttcc tagcctactt aattctcatt acgatcggct
     3181 gctcaccccg acagctgact tagctgcggc tgaccttgct gatgttttct ctaatgggga
     3241 ttccttgctt tattctaagc taagtccaga gcaggaggga cgtgtcctta ggctgataca
     3301 gtctggtaag attagggcaa cttatctagc caaggacaaa aagacaatca aaaccgagac
     3361 ttactatcag gtcaatagat tagccttaca ggagcataag atttcaaatc gggctaaaaa
     3421 gcgccaagcc ttaaaggctt atttgttagc caatccacaa aaagataagc tagccaagct
     3481 ttatcaggat tattctagag aggttgttag ctattttgtg accaaccagc tgatcgagct
     3541 tgaggagcga cgtgtcaatc gcagtgagga ttatttcaat cacatcaagg cagccccact
     3601 cttaaagctt aatcagcagc agcagcaagc tgttgaccag attacgaagg ctgttggcag
     3661 agaggctaag ccctttttac tggaaggtat tacaggctct ggcaagacag aggtctatct
     3721 tcatgtgatt gcgcatgtgc ttgagcaagg aaagacagct attgtcttag tgccagaaat
     3781 ctccctcacg cctcaaatga cctctcgatt tatttcccgc tttggaagac aggtcgctat
     3841 tatgcattca ggtttgtcag atggagaaaa atttgacgaa tggcagaaaa ttaagacagg
     3901 gcaggctaga gtggtggtcg gtgctcgctc tgctattttt tcacctttag aaaatattgg
     3961 agccattatt attgatgagg agcatgaggc cacctacaag caggaatcta atcccagata
     4021 ccatgccaga gatgtagctc tcattcgtgc aaggcaccat aaggctgcct tagtgatggg
     4081 ctcagcgacc cctagtattg atagtcgcgc tagagccagc aagggactgt atcagtttat
     4141 ccagctgact gagagagcca atcctcttgc cagtatgcct caggttgaga ttgttgattt
     4201 tcgagattat attggtcagc aggaggttag cagcttcacc ccttatttga ttgataaact
     4261 caaagagcgt cttgctagaa aagagcaggc tgttttgatg ctcaacaggc gtggctactc
     4321 tagctttatc atgtgtcgag attgtggcta tgttgatcaa tgtccaaatt gtgatatttc
     4381 cttaaccctc cacatggata cgaaaaccat gaattgtcac tattgcggct ttcaaagggc
     4441 tattccgaag ctatgcccta gctgtcaagg caaaagcata cgctattatg gaacagggac
     4501 gcaaaaagcc tatgatgagc tcaagcaagt gttgccggaa gctagaatat tacgaatgga
     4561 cgtagacacg acacgtaaaa aaggaagcca tgaggctatt ttaagccagt ttggaaatgg
     4621 tgatgctgat gtgctgcttg ggacacaaat gattgcaaag gggttggatt ttcccaacgt
     4681 caccctagta ggtgttttaa atgcagatac ttccttgcat ttacctgatt ttagggcatc
     4741 ggagcgaacc tttcaattgc tgactcaggt tgcaggacgt gcaggacgtg cagacaagcc
     4801 aggtgaagtc ctgattcaga cctacaatcc tgagcattac gcgattcaac tggccaaaaa
     4861 gcaggatttt gaagcctttt acgcttatga aatggggatt cgacgaaagc taggctatcc
     4921 tccctattat ttcacagtag gtctgaccct atcgcataag agtgagcaag aggtggtcaa
     4981 aaaggcctat caactgctga ccatattgaa gcagggcttg tctgatcaga tcagaatatt
     5041 agggccaacg ccaaagccaa ttgcaagaac gcacaatctt taccattatc agattatttt
     5101 gaagtatcgc tttgaggatc agcttgaagc taccctgaat caaattcttg attggagcca
     5161 agagcaggat aatcgcgagc taaaggttat cattgatcag gagccacaga gctttatgta
     5221 agtgttcttt accggacttt gcgccaagct atgctataat gaaaaagaaa gaaaatagag
     5281 gacatagatg acaagattaa tttttatggg cactccccaa ttttcagcaa ctgttttgca
     5341 gggcttacta gaaaaaccag cctatgacat tttagcggtc gtgacccagc ctgatcgtgc
     5401 ggttggtcgc aaaaaagaca tcacaatgac gcctgttaaa aagctggcgc ttgcacatca
     5461 gctgcctgtt tttcagcctg agaagctatc tggttcacag gagctagcag atatcatggc
     5521 attaggagca gacgggattg taacggcagc ctttgggcaa tttttaccaa cagtcttatt
     5581 ggattcggtg acatttgctg ttaatgtgca cgcgtcctta cttcctaaat atcgtggtgg
     5641 cgctccgatc cattatgcta ttatcaatgg tgacaaggaa gctggagtta ccattatgga
     5701 gatggttaag gagatggacg ctggggatat gatatcaagc gcaagccttc caattttaga
     5761 tactgataat gttggtacca tgtttgataa gctggccatt ctaggacgag atttattatt
     5821 gaaaaccttg cctgattact tgtctggtga cctaaagcca gttcctcaag accatagcca
     5881 agccaccttt tctcccaatc tttcagcaga agaagaaaga ctggactggt caaagccagc
     5941 aagagaggtg tttaatcata tcagaggaat gaacccttgg ccggtggctc ataccttatt
     6001 agatgggcag cgcttcaaaa tttatgaggc tgaattggct gaaggctctg gatctgctgg
     6061 gcaaatcatc gctaaaacta aaaaagcatt ggtcgtagca gcaggtgagg gggctctatc
     6121 cttgacgctc gttcaaccag caggcaagcc aaagatgcct attgttgact ttttaaatgg
     6181 tattggcaga agcctagagg tgggtgatgt ccttggcgaa tgattggaaa aaatcagcta
     6241 gaggacaggc gctgcttatc gttgaggata tttttgatca tggagcctat tctaaccttg
     6301 ccttgaagca ccagctggcg aatcagtttt taagtgataa ggacaaggct ctagtcacag
     6361 agattgttta cgggactatc tctaggaaga taaccctaga atggtatctg gctcactata
     6421 ttgaggaccg agacaggctg gataaatggg tttattatct cttgatgctt agcctttacc
     6481 agctggctta cctagacaag gtgcctgctc atgctattgt taatgacgct gttaatcttg
     6541 ccaaggcgag agctcatggc agaggagcag ataagctggt caatgccgtt ttgcgccagc
     6601 tgaccaataa gcccttacca gatatcaaga gcatcaagcg aaaaaacaaa tactatgctg
     6661 ttgcttactc agtaccggtc tggctagtca aaaaattgat cgaccaattt ggcgaggagc
     6721 gagctgtagc aatcatggaa agtctttttg tgagaagcag agccagcata cgtgtcacag
     6781 atctgacaaa gcttgatgag atcaagcagg caacaggatc agagcaatca ttacttgcta
     6841 ggactggtct gaccaagaga gctggcaatt ttgctgccag cagttatttc atcaatgggg
     6901 acattacgat ccaagatgag accagtcagc tagttgcccc gacgctggat attcaagggc
     6961 aggaaatgat tttagatgct tgtagtgcac ccggagggaa aacagctcac attgcctctt
     7021 atttgacgag cggcaaagta gtggcccttg atttgtatga gcacaagctg gccttagtga
     7081 atgaaaatgc taagcgtcta ggggtagcag atcggattga aactaaggtg cttgatgcta
     7141 gagaggttca taagcatttt gcgaagaaca gctttgataa gattttagtt gatgctccct
     7201 gctctggtat aggcctcatc aggcgtaagc cagatattaa atacaacaag gaagggcagg
     7261 acttccagca attgcaggaa attcagctgg agatattgtc tagcgtttgt caaacgctgc
     7321 gaaaaggtgg tataataacc tatagcactt gtacgatttt tgatgaagag aatttccaag
     7381 ttattgacaa atttttacaa cgtcatccta attttgaaca agtaacactc aagcatgcac
     7441 aagcagatat tgtcaaggac ggttgtctta tgattacacc agagcaatac cagactgatg
     7501 gcttctttat tgggcaagtc agacgagtct tgtagtattt aggaggagac tgacctagtc
     7561 agaaaagatt atatgaagat ttcattaaaa accgatattg ggcaaaagcg ctcaaacaat
     7621 caagatttta tcaacaaatt tgataataaa aaaggcatta cccttgttat cctagcagat
     7681 ggtatgggag gtcatagggc aggaaatatt gccagtgaga tgaccgttac agacctaggt
     7741 agagagtggg ttaagacaga ttttactgag cttagtcaga tcaaggattg gttgttaaca
     7801 accatcgaag cagagaacca acgtatctac gacttgggac aatctgaaga ctataaggga
     7861 atgggaacaa ccgttgaggc agttgctcta gtagattcta atgcgattta tgcccatatt
     7921 ggcgattctc gtatcggctt ggttcatgag ggaaattata gtcttttaac cagtgatcat
     7981 tccttggtta atgccctagt gaaggctggt cagattaccg aagaggaggc tgctagccac
     8041 ccacaaaaaa atatcatcac acaatctata ggtcaagctt caccggtaga gccagactta
     8101 ggtgtcaagg ttttagaaaa gggcgattac ctagtgatta atagtgatgg cttaaccaat
     8161 atgattgcta atgaggagat tgttgacata ttatgtcaag acatcagcct tgatgagaaa
     8221 aatcaagcct tgattgacct ggcaaaccaa agaggaggcc tagacaacat caccgttgct
     8281 ttggtgcata aggaaagcgg ggaagcagaa tgattcagat tggcaagcta tttgctggtc
     8341 gttatcgcat tctaaaatct ataggccgcg gtggtatggc ggatgtttat ttagcaaacg
     8401 atttgattct ggataatgag gacgttgcca ttaaggtctt gcggaccaat tatcaaacag
     8461 atcaggttgc tgttgcgcgt tttcaaagag aagcgcgagc catggctgaa ttaaatcacc
     8521 ccaatattgt tgccattcgg gatataggcg aggaagacgg acagcaattt ttagtaatgg
     8581 aatatgttga tggctctgac ttgaaaaaat acattcagga tcatgcgcca ttatctaaca
     8641 atgaggtggt gagaatcatg gaagaggttc tttctgccat gactctggcc caccaaaaag
     8701 gaattgttca cagggattta aagcctcaaa acattctttt gaccaaatca agtgttgtta
     8761 aggttacaga ttttgggatt gccgttgcct ttgcagagac cagtctaacc cagacaaatt
     8821 ctatgctagg aagtgtgcat tacctctcac ctgagcaagc gcgtggttct aaagcgacga
     8881 ttcaaagtga tatttacgcg atgggaatta tgctctttga aatgctaaca gggcatattc
     8941 cttatgatgg cgatagcgct gtgacgattg ctttgcagca ttttcaaaag ccgctgccct
     9001 ctatcattga tgaaaatcct aatgtgcctc aagccttgga aaacgtcgtt attcgggcta
     9061 ctgccaaaaa gctaagtgac cgttatcgct cgacctttga gatgagcagg gatttgatga
     9121 cagcccttag ctataaccgc agtcgtgagc gtaaggttgt ctttgatgat gtcgaaagca
     9181 caaagccctt gccaaaggta acaccgactc ctgtaacagc acctaaggta tcaaatgcta
     9241 gtcaggcatc tgcggcagtt gatgctagac ttgagcagac tagccagatg gatactctgc
     9301 aaaagcctca aaaaaagaaa aaaaatgggc gttttctagg aacactctta aaaatcttgt
     9361 tttccttttt tgttgttggt gtggctcttt ttgcttattt ggtcttgacc aagccaacta
     9421 cggttaaggt tcctgatgtg acaggctcta gtctcaatgc tgccaagcag gtcttggagg
     9481 aggcgggact aaaggtcggt aaggtccatc agattgaaag tgacacagtt agtgaggatc
     9541 aggtggttaa gacaaatcct caagctggct cagctaagcg aaaaggctcc agcgttgacc
     9601 tttacctttc gatcggaaat aaaggctttg agatggaaaa ttataaggga caggattatc
     9661 aagatgtgat gaccagtctg actgagacct atggcgtacc aaagtcaaaa atcaagattg
     9721 agcgtatcgt gacaaatgaa taccctgaaa acaccgttat tagccagtct ccaagcgcag
     9781 gagaaaaatt taacccagct ggtaaatcca agattaccct cagtgtagca gtgggtgata
     9841 cagtcatcat gccaatggta actgagtaca gctatgcaga tgcagtcaat acactaacag
     9901 ctttaggaat tgatgccgca agaatcaagg cctatgtacc aagctccagc tctccgacag
     9961 gctttgtgca ggtgagctcc ccaagctcaa aggcggttgt cagtgggcaa acaccgtatt
    10021 atggtaccca gattagcctt tctgaaaagg gtgatattag cctctacctc taccctgagg
    10081 agacacgtgc atcaagcagc tcatcgagct ctgatacctc ggctcctaat ccatcagctg
    10141 gagatacaac agactcaagc agtcataccg aattaggtca aaatgacgct gttacaacac
    10201 cgtaaacgta aataggatat agaatatctg gcttgcccat agttgctaag ctaggtattc
    10261 ttttttacta gaatgccact caagggtgaa tttttgctta atttttgata aaatgtcagg
    10321 gtaatggaag gagtctaatg aaaaaatttc aattctttct gcttgttgaa tgcatgctgc
    10381 tggctatggg gattatgacc attttggcca acgacttatc aagctttatt ttaattttgg
    10441 tcttgatttt attggctctg cgtttttata atcaagatac ccgcaatagc tttttgctaa
    10501 cagttagctt attgctttta ttcttaattt ttatgctgaa cccttatatt attatggcgg
    10561 ttctgttggg gattgtgtat gtgattatca atcatttttc acaggtaaaa aagaagaatc
    10621 gatttgccct cattcggttt gcagaagaaa aaatgactgt gcgacaggtc aaaaatcaat
    10681 ggcttggcgc agctaactat gaaagtgatt attattcctt tgaggatatc aatattattc
    10741 gtgcctctgg caatgatacg attgatctga caaatgtgat tgtgactgga atggacaatg
    10801 tcatcattat cagaaagatc tttggcaaca caaagatcct agtgcctatt gatgtggctg
    10861 ttaccttaga ggtcagctct atctatgcta gtgttgattt ttttgagctt caagagtacg
    10921 atttacgaaa tgaatccatc accctaggag aggccgagga cagcagttta aagaaggtta
    10981 agattatcgt atccactata gcaggaaatg tcgaggtggc tagacgatga aaaaaaggta
    11041 ttatgctttg gtctggcttt attcgactat aaccatttta tcaattgttt ttgttgtgat
    11101 ggataatctg gggatcacct ttgactactt gcggagccat ttatggcagc tagagcgctt
    11161 ggtgttttca gttgtgctgc ttatcatctc tgtaaccttg ctgttgcttt tgttgtggat
    11221 tattttagat gataatagca agcggagcat caataaaaat ttacgcagga ttctcaacaa
    11281 tcaaagaatt catttggagg agacctctga aatcaacacg aatttgacca gactttctgc
    11341 gaaaatgtct catataacaa ccaatatcca gaaaaaagag aatgcttata ttttagatag
    11401 tcaaaaaatt gttcaacagg agcgtaaacg aatcgctaga gacctgcacg acactgttag
    11461 tcaagaattg tttgcttcgt cgatgatttt gtcaggggtt tctatgagcc tagatcagat
    11521 ggataaggag cagctacagc aacaattagt tactgttgaa gccatgctgc aaaatgctca
    11581 aaatgattta cgcattttat tattgcacct gcgcccgaca gaattggcaa atcgtagcct
    11641 gtcagagggc tttacgatga ttctcaagga actaactgat aaaagcggca ttgaggttgt
    11701 ctataaagaa aatattggca ctctgccaaa ggccatagag gataatctct ttaggatcgc
    11761 tcaggaattt atcagcaata ccctcaagca tgctaaggcg agccgccttg aggtgtactt
    11821 gaaccaaaca ccaacagaac tacagctaaa aatggttgat aatggggttg gttttgacat
    11881 gggtcaggtt agggaattaa gctatggcct taaaaatatt gaagatcgtg tgaatgacct
    11941 ggctggaacg cttcgtttga ttagtcaaaa aggaaagggc gtttcgatgg acattagact
    12001 gccacttgtg atgggagatg aagatgagta atataaccgt aatattagtt gatgaccatg
    12061 aaatggtccg aatgggctta aaaagcttct taaatttgca gcaagatgtt gatgtcatag
    12121 gtgaggcttc taatggtcgt gagggagttg agcttgccct tgaattgaga ccagatgtcg
    12181 tggttatgga tttggtaatg cctgaattag gaggtgtaga ggcgacccta gaaatactct
    12241 ccaaatggaa ggaagcaagg gtgttggtgt taacctccta tcttgataat gaaaaaattt
    12301 accctgtcat tgatgcagga gctaagggct atatgttaaa aacatcaagt gcagctgaaa
    12361 tcttaaatgc cattagaaag gttgctaagg gcgagcttgc cattgaaacg gaggttgaca
    12421 agaagattaa ggcacatgat cagcagccta atttacatga agagcttaca gcgcgtgaat
    12481 acgatatttt gcatttattg gccaagggct atgataacca gaccattgct gatgagcttt
    12541 ttatttcctt gaagacagtt aagactcacg tgtcaaatat tttagccaaa ttgcaggttg
    12601 atgatcgtac tcaggctgtt gtatacgctt tccgacatca tttagtgcct caagatgatc
    12661 attaatgcta taatagtact attgcatgga ggaaagtatg gacgcaaaac taaagtataa
    12721 ggccaagaaa atcaagatgg ttttctttga catagatgat accctgcgcg taaagaacac
    12781 aggctatatg ccagagtcta tccagagggt tttcaaagag ctcaagaaaa aagggatcct
    12841 aacaggaatt gcttcgggtc gcgccagata tggtgtgccc aaggaggttc aggatttaca
    12901 ggcagattat tgtgttaagc taaatggtgc ttatgtgaag gacaatcaaa aaaacattat
    12961 ctttcaggca cctatcccag cagacactgt tgtagcctat aaaaaatggg ccaatgcagt
    13021 cggcattgat tatggcatgg caggacgtca cgaggctgtc ttatcagctc gtaacgagat
    13081 gattagtgat gctattgata aggtttactc cacactagag gtatgcccgg attacaatga
    13141 gcaccatgat gtctaccaaa tgtggacctt tgaggacaag ggagatgacc tgcaattacc
    13201 tgttgaattg gctgagcagc ttcgcctagt aaggtggcat gatcactcct ctgatgtggt
    13261 cctaaagggc acctctaagg ctctaggtgt atcaaaggtt gttgagcatt tgggcttaag
    13321 gcctgaaaat atcctggtct ttggtgatga gctcaatgat ttagagctat ttgattatgc
    13381 tggcatcagc attgctatgg gggtttctca cccacaatta caagaaaaag cagattttat
    13441 tactaaaaca gttgaagaaa acggcatttt atatgccttg gaggaattag gtttgattga
    13501 caaagaatta cattttccgc agctagattt ggctggccat gaaggaccaa gagtggtgat
    13561 gaaaacaaat catggtgagc tgacattggc tttatttcca gagcatgctc caaaaacagt
    13621 tgctaacttc ttaggtctag ctaaggaagg ctactataat ggtgttattt tccatcgtat
    13681 tattgcagat tttatgattc aaggtggaga tccgactggc actggaatgg gtgggcaatc
    13741 catctatggt caaagctttg aggatgagtt ttcagaggaa ttgtacaacc ttcgcggagc
    13801 cctttcgatg gctaatgcag gaccaaatac aaacggcagc caattcttta tcgtccaaaa
    13861 tacaagcctt ccttattctc aaaaggaatt agagcgtggt ggctggccaa aggacattgc
    13921 agcagcctac gctgaacatg gggggactcc ttacctggat cgtcgccata cagtatttgg
    13981 tcagttggct gatgaagcct cttatcaggt cttggataac attgctgctg tcgaaacagg
    14041 ggcacaagac aagccaaaag aggacgttgt cattgaggcc atcgaggtat ttgattgatg
    14101 aaaattggcg ataagctgca tgggaccatt acaggaatca aaccctatgg agcctttgtt
    14161 gcccttgaaa atgggacaac aggtctcatt catatttcag aaattaagac gggatttatt
    14221 gataatattc atcagatcct aagacttggt gaggcggttt tagttcaggt cattgactat
    14281 gacgaataca gtcataaggt cagcctgtcc ttgagaactt tggaggagga aaagcatcat
    14341 gtgtcaagtc atcatcgctt ttcaaacagc cgttataaga ttggctttaa gcctcttgaa
    14401 gccagcttac ccaattggat tgaggaaggc ttagaccact ttaagcagga aaaatcgtaa
    14461 acagacttgg aaacataaaa aaccgagaaa cagctatatg aactgttcct cggttttttg
    14521 ctatcagctc tggaccagtc accttactta tctcaaagct atcttcaaaa aaagccaatt
    14581 gtgattgcta gtcctctttg aacatcttag cctactagct tgagtctttt ttactgtggt
    14641 gaaagcggct aggaaagcct atttccaaga agctagaagc tctggggcgc ttaggcgtgg
    14701 tatgctatgt ttattgttaa aaaggaatca aagtaagcat ttttccatat gctagctgac
    14761 tggcctttaa tggtgactaa gtaagagcga tgatttatgc ttgaaagctt attctagctg
    14821 ctagggctgg tgcttatatg attattctaa tcaaactgat aaagggcagt agacaggtac
    14881 cgctcaccat tatctggtaa tatagctaag acctttttac cttttccaag ctccttagca
    14941 gcttggatag cagcataaac agcggctcca gaagaaatgc ctacaagaaa gccctcctta
    15001 gccccgattg accgagcagt ggcaagggca gcctctgacg ctactcgaat gatgtggtca
    15061 taggcctttg tatctaaggt atttgggata aagccagctg aaatcccttg aatcttgtgc
    15121 ggagaagact cttcaccaga taagacggca gattcatctg cttccacagc atagatagaa
    15181 atatcaggat taacagcctt taaggcatgc gcaacgccag aaatagtgcc accagttccc
    15241 acaccagaaa caaaggcatc aagtcctttt tctccaaaaa ccgcgataat ttcttgccct
    15301 gttgtctctt catgaacctt gggatttgca ggattgtcaa attgcgaggg catccaagca
    15361 ccggtctctc tggcaatctc ttctgcttta gcaatcgcac ctttcatccc atcactacct
    15421 ggggttaaaa cgagctctgc tccgtaagct tgaatgattt gacgtctttc aatactcatt
    15481 gtctcaggca ttacaatgag cactcggtag ccttttgcag ccccaaccca ggataagcca
    15541 atccctgtat tgccactggt tggctcaacg attgtatcac ctggcttgat catgcctgct
    15601 ttctcagcag cttcaatcat tgcaagtgct atgcgatcct taactgaaga gcctggatta
    15661 aaagcttcta gcttgacata aatatcggca gcctcctctg gactggtgtt tctcaattta
    15721 ataatagggg ttttcccaac caactctgta atgttgtgat atagctttga cataggtcct
    15781 cctttttatc cttgtatcaa tacatgctta tataaaagta tatagctaat aatcgacaaa
    15841 gtaaaatagc catttactat cgtagtgata aagagacgct atcactgttc atgctaattg
    15901 gcaggcaaaa cagggacctc aatcctttgc gattcgatct cttcaaagga aaccttgcca
    15961 tgataatgct caatcaatgc cttagaaata ctctccaagc gctcaggatc aaagtaaata
    16021 gctgttctga cgacatcaga aaattcggta ttcatttcaa tcaatgcttc ttgctccaga
    16081 aaattaggat agatttggta ttgagggtag gtgaggctga ttgctagtcc agtttgtttt
    16141 tttacctcaa cgacctttaa ggcctgaata gctgccgcag ttacgccgga gtaagcgcga
    16201 atgagccctc cagctcctaa tttaacacct ccaaaatagc gtgtcacaac agctacaaga
    16261 ttggttaatt cctgcctttc taagacagat agcatgggaa taccagcagt accagatggc
    16321 tcaccatcat cgcttgaccg cttggtttgt cctttgtctc cgataatcat agcagagcag
    16381 gaatgattgg ccttatagtg cttttttttg atgtcagcaa taaaggctct ggcctcctct
    16441 tctgtgtaga cgcgtttgat ttggcaaata aagcgagatt ttttgatgct ttcctcaaaa
    16501 agcccatcag tcataatagt tttataatct tccataagaa aattttacaa aaaatgctga
    16561 tatttagcaa aataattcgg ataataaggt atggagaata tcgaaaatta ctatggacgt
    16621 cttttacccg aaaggcaatg cccaaaggct gtttctgcct gggcttgcag cttacaaagc
    16681 atgatcacta aaaagggaac gttatactgc caacgctgta gcagtttaat tgagaaggct
    16741 catcagctgc ctagcggtgc ttactactgt agagcctgtc ttgtttttgg tcgaaaccaa
    16801 tctgatcgcc ccttgctcta ttttccaccg gcttcttttc caaagggaca ttatctgagg
    16861 tggcaaggac agctcacgac atatcaggca gctatctctc atcagcttac taaccatgtt
    16921 aagctcaagc aagacacctt agttcatgcg gttactggtg ctggcaaaac agagatgatg
    16981 tatgaagcta ttgcagcagt tgttaataag ggtggctggg tctgcattgc tagtccacga
    17041 gttgatgttt gcatagagct tgaaaaacga ctatcgcggg acttttcctg tcaagtctgc
    17101 cttatgcatg ctgagtcaga ggtttatcat agaagcccca ttatcgttgc cacaacacat
    17161 caattgatga ccttttacca tgcttttgat ctgctcatta ttgacgaagt agatgccttc
    17221 ccctttgtca ataatcgtca attaaaccat gctgctcatc aggctgcaaa agcagatgca
    17281 gtgacagtat acctaacagc aacctctaca agagatttag agcgcaaggt cagcaaaaag
    17341 agcttgtcaa attgacgttg gcaagaagat tccatggcaa gcccttagtt gttccaaagt
    17401 atcaaagatt attctccctt ttagaggcta tcaatcgtgg gaaattgcct agaaggttca
    17461 tcaccctagt caaaaaacaa agggcaaccg gctatcctct tttaatcttt tttccgatta
    17521 ttgagctggc tgagcaatgc tgtcagctgc tccacaagta ttttcctaag gaaactattg
    17581 ctcatgcttc cagtcagtca tcaaatcgaa tggctatcat tgagcaattc agacaaggac
    17641 aaatcactat acttatatca acaaccattt tggaaagagg tgtgaccttt ccaaccgtag
    17701 atgtctttgt cttattagcc aatcatcgcc tttacacaag cagcagtctt attcaaatca
    17761 agggttgaaa actttgtaat ttttggcatt aaaaagtcca atgaatgtct atattatctc
    17821 tatcaacttt aacacgttga acaagcagct caacagcata tttttgaccc tcatagtcca
    17881 tggtccatac atcaggcaag gcgagaaagt cagcaatggt ttcttgtctg tcaagttcat
    17941 catcgttatc acaagtttta tctagttcgt tctctagcaa tcttttttta gctataagag
    18001 tgtttgtctg agttttgagg tcttcaagag ttatcagatc gttaagataa agattgttta
    18061 gcttagagag ttgattcact gttttattga tattagcttc aattctttca cgcttgtatt
    18121 ttaattcgtg atcctcaata tgtttttgtc tgctcgctat tgacggatct ttttgtattt
    18181 tggctatctc gtgtaacaca taatcctcca aggtttctgc atcgtaaagt ggtgtgtcgc
    18241 aactagctgt tcgttttggc ctactattta ggcaatagta ttttttggat cttttgcctt
    18301 ctttttttct tggtctgcca agctcaagcc ccattcttga gccacattga cgacatctta
    18361 aaaatttact tagcatatac ttcgcctgaa aaggtattgt gtagtggttt tcttcgattc
    18421 ctaatcttct gcgttgcctt tctctttggg ttttatcaaa tagctctttt gtaataattg
    18481 gttgatgatt tccggggaat aatttattat tataccttgt cataccataa tagacaggat
    18541 tatctaatag atgcttaaca ccatgtggaa accaagtgca atccttaccg ttgtagtcca
    18601 tcttattaag tttatccact attttttgaa tagacatacc tttgagataa tctgtatata
    18661 tcattttaac tataggcgct tttgcaggat ctaaaatcaa ttcgcctttt tctttgttgt
    18721 aatcatagcc aaaaggggta taagtccagg ccatagtttt tccggatttt gctcttccga
    18781 tttttcccat tgtcattctc tctgttatct gttctcgttc gaattcggca attgcagata
    18841 gcaatgtgag gaatagatta cccatagccg aagaagtgtc aatattttct tgcagactga
    18901 caaaatggat attgttttgg ttaaaaacat ctttaactaa gtaaagagta tctctgacac
    18961 ttcgggagag tctgtctagc ttataaacta agattgtatc aaatcgttta tgctttgcgt
    19021 ctgtaattag tttagacatg gcgggacggt ctatcttacc tcctgaaaag ccagcatcag
    19081 tgtactcctc atatataatc caacccatag cttcgcagta tttgatcaaa ctgtctatct
    19141 gaccttgtat tgaatagccc tcctctgcct gatttgttgt actgactcta acataaatag
    19201 cgacttttct tgttgtaatc attgtttttc acctcatttt tatgttaaaa tgggtatagt
    19261 aaagagacct actgcaaagc aggtttttac tatacacgtt cgcctcacgc tcgcatcgac
    19321 caaagttgag cgtgaggctt tttattattg tgtttagatt ataaaaagca ctaaaaatac
    19381 aatggaagca gtgccccaat aaagctgttc ttttttattc caaggaatct cttcatttga
    19441 atgtgatata aggtgactgt tgttttcgtc aacttcatca tcggaattaa cttttttaga
    19501 aaggtttaca gcattagcac cgcagcctat aaataaaatt aggaataacc atttcatatt
    19561 taacccccat ttttcaagat actttgacgg tattcaaacg cttcagcttc ttcggtaatc
    19621 tcaatagcta attctttatg attttctaga acttctttga ttttagcaaa cggaactcta
    19681 aagtactctt ttcgactgtt tattttattt actttatacg cttcaaattt attatgtaac
    19741 tcagactcta aagcaaaagc ttcctcacta aagataagcg catgaacatc aaaagtaaaa
    19801 ggcaccgatg cactccccaa ttcgcgaata cgatccattg ggtctaaacg tcttgttact
    19861 ccaattttat aaacatcttc tccaaaagca cctatattag aaataacata gacatatcca
    19921 gctgttgcat gtccttctct ataatcaatg tcttcttcaa tcttatcaag ttctgagagc
    19981 ttgttttggt attcaattaa ttgcaattgt aatttctctt gttctttcgg agaagcgtta
    20041 gcaagcatca cttcgacgtt cttgaccatt tgtaaaaagt gcttcctgtc tttttcaagt
    20101 tgttttcttt tagcagtaat ctcagcttga agttttttat cttctctttc tcttgcacgc
    20161 tgttctctta gaatttcttt ttcttcttgt ttttgcaatt cgtattcagc agctaatctc
    20221 aattcttgtg cttttaaatc taaatattta aaggtaagtt ggatcaagtt cctttcatac
    20281 attttattta attgttcgaa agccttctga agagtttgca cttttttatc tacatttacg
    20341 acagacactt taactagtaa ggcatcggct tcaccattaa agccgcggat tgcagctttc
    20401 ctaagttggt tctgcattgc tttacctttt gctgcactac catctagagt catgggggaa
    20461 attatgcttg tagcttcacc attttttatg agtgtttttt gtttcattcg taacgtatct
    20521 aaagcatctt tatatttagt actatgggaa aatttatact ggcgttcaaa aaaaccatat
    20581 tcttgaaggt ctaatgtatc attggctaat gcaatttctt ctttaatttc cctcaatttt
    20641 tctttttcat tttcaatttt ttgttgtaac ttttgtaatt tcttttctag agccacatct
    20701 tttatttttc cgaaattaaa caatcccata acacacctca atattctttg ggcataaagt
    20761 tgccgacgat tttgccgatt atacgcggat cttcgctaaa aggagcaaac ttatccttgt
    20821 attttttatt taaagaaact aatcttaatc catctttttc cctataaact ttcttaatat
    20881 aggtttgtcc gtcccattca acagcataga caccgccttc gtaatcaaag ccagtttgct
    20941 ttataagcac aacttcacca tttaaataag tgggctccat agaatcgccg aaaacccaag
    21001 aagcgaaatc gtagtctaat tcttcttcgt aaaagacagt atcatagttc ccgtcaccaa
    21061 aatatccata acctgtccca gctgaaagct tctcgtaaac tttatactca tagagttttt
    21121 tctccataga agtcatttta tttttttgtt cttttaattg atctgttgca aagtctaaaa
    21181 ctttttgctt acgaggaaca tttaattcca cgacagttgt ggttattttt ttgacaagtg
    21241 gagaagtagg aatcttaagt tcgtgatttt tcttacgagg tgcaaatctt ggatctatat
    21301 ctgatttcat taacccaaaa taatcggcta ttttttggac attaccggga ataggtaaag
    21361 atgtcccttt tacgtaacct gtgagcgtac ttggtggtat tcctgtagcc tttgagagtt
    21421 caacttgctt tgtatttgtt tcgttgagca gatcattgaa tttgctcgaa aagaatccta
    21481 acgcctctat ttcttgaggt gttaatctac ctcttcctct tgccatatta ttttcctttc
    21541 gatttttata c
//
LOCUS       DARYXW010000029        21453 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.029, whole genome shotgun sequence.
ACCESSION   DARYXW010000029 DARYXW010000000
VERSION     DARYXW010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21453)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21453)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21453
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.029"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            135..908
                     /locus_tag="TV191_000876"
     CDS             135..908
                     /locus_tag="TV191_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEL1507406.1"
                     /translation="MIEIFDTHTHLNVDHFSGKEEEELALAKEFGVSYHNVVGFDQET
                     IDQALTLADAYREVYATIGWHPTEAGSYTQAVEDSLIACLKHPKVVALGEIGLDYYWM
                     EDPKEVQIEVFKRQLQLAKDHDLPFVVHTRDALEDTYQVLKEAGVGPRGGIMHSYSGS
                     LEMAQRFVDLGMLISFSGVVTFKKAVDVQEAARHLPLDKLLVETDAPYLAPVPKRGRE
                     NHTAYTRYVVEKIAELRGLSVEEIAAATTANAKRVFRID"
     gene            880..1476
                     /gene="rnmV"
                     /locus_tag="TV191_000877"
     CDS             880..1476
                     /gene="rnmV"
                     /locus_tag="TV191_000877"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEL1507407.1"
                     /translation="MQRGCLELTEKLKIQEVIVVEGKDDTANLQRFYDVDTYETKGSA
                     ITDEDLERIDRLNKLRGVIVFTDPDYHGERIRKLIMRAVPTARHAFLRRHEAKPRSKS
                     KGRSLGVEHASFEDLQKALSQVTQSFDDESYFDISQTDLIRLGLLLAADSRKRREYLG
                     EVLRIGYSNGKQLLKRLKLFGITLSEVEDVMTSYQTEQ"
     gene            1820..2692
                     /gene="rsmA"
                     /locus_tag="TV191_000878"
     CDS             1820..2692
                     /gene="rsmA"
                     /locus_tag="TV191_000878"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015911942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEL1507408.1"
                     /translation="MRIADYSVTKSILDRYGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DKSVNVIEIGPGIGALTEFLAERAAEVMAFEIDERLVPILADTLRDFDNVQVVNQDIL
                     KADLQTQLKQFSNPDLPIKVVANLPYYITTPILMHLIESKIPFQEFVVMMQREVADRI
                     SAEPNTKAYGSLSIAVQYYMTAKIAFVVPRTVFVPAPNVDSAILKMTRRDQPLIEVQD
                     EDFFFRVSRVGFVHRRKTLWNNLVSHFGKAEDTKARLEQGLALAGIKPSIRGEALSIQ
                     DFGRLADALKQVGF"
     gene            2853..3725
                     /gene="rsgA"
                     /locus_tag="TV191_000879"
     CDS             2853..3725
                     /gene="rsgA"
                     /locus_tag="TV191_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEL1507409.1"
                     /translation="MQGKIIKALAGFYYVESEGQVYQTRARGNFRKRGQTPYVGDLVE
                     FSAEDNSEGYILAIAERKNSLVRPPIVNIDQAAVIMSAKEPDFNTNLLDRFLILLEHK
                     AIHPIIYISKIDLLEQPESIEAIGQHYRAIGYDFVTSLSHLLPLLAGKTTVFMGQTGV
                     GKSTLLNRIAPELALETGDISDSLGRGRHTTRAVSFYDAYNGKIADTPGFSSLDYGID
                     NAEDLNEAFPELRRLSHSCKFRSCTHTHEPKCAVKEALGNGELWSVRYQNYLQFLSEI
                     ENRRETYQKVSKRK"
     gene            3734..4396
                     /locus_tag="TV191_000880"
     CDS             3734..4396
                     /locus_tag="TV191_000880"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEL1507410.1"
                     /translation="MSSLKIAPSILAADYACFAAELARIEKTDAEYVHIDIMDGQFVP
                     NISFGADVVASMRKHSKLVFDCHLMVVNPERYVEAFAQAGADIMTIHVESTLHSHGAL
                     QKIRAAGMKAGVVINPGTPVSAVEPLLSLVDQVLIMTVNPGFGGQAFIPECLEKVAAI
                     AKMRDERGLSFDIEVDGGVDDKTIRACYQAGANVFVAGSYLFKAADLAAQVQTLRAAL
                     NG"
     gene            4389..5021
                     /locus_tag="TV191_000881"
     CDS             4389..5021
                     /locus_tag="TV191_000881"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEL1507411.1"
                     /translation="MVKVALFAGGDLSYFTCDFDYFVGIDRGSLFLLENGLPLNMAVG
                     DFDSIPQVAFEVVKEQAELLVQASPEKNDTDTELALKEVFTRFPEAEVTIFGAFGGRL
                     DHLLSNVFLPADPELAPFMAQICLRDQQNAISYRSSGWQTIRQDKDMTYVAFMADGDA
                     DLTITGAKFDLTTSNFFKKKVYASNEFIDQPIKVHVPKGYLIIIQSKDRS"
     gene            5023..6294
                     /locus_tag="TV191_000882"
     CDS             5023..6294
                     /locus_tag="TV191_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEL1507412.1"
                     /translation="MDLILFVLVLVLIGLAAYSFVSIKHLQSRLEKALDDNADNLSDQ
                     LTYQLDMANKSQLLELSTVMNRQQNELFQQLMVIRDTLHQGLAENRDRSDQRLETMTQ
                     SLSQAVKNLQDSNEKRLEEMRHTVEEKLEKTLKNRLQTSFEAVSKQLESVNQGLGEMR
                     TVAKDVGTLNKVLSNTKTRGILGELQLGQIVEDIMTANQYEREFATVSGSSDRVEYAI
                     KLPGNGQGDYIYLPIDSKFPLEDYYRLEDAYEAGDRAAIETSRKALLAAIKRFAKSIH
                     SKYLNPPETTNFGIMFLPTEGLYSEVVRNPAFFDSLRREENIVVAGPSTLSALLNSLS
                     VGFKTLNLQKNADDISKILGNVKLEFEKFGGLLAKAQKQLNTANHTLDQLMSTRTKAI
                     VRALATVEGYQDQSTQSLLHIPLLEEADDED"
     gene            6284..7222
                     /locus_tag="TV191_000883"
     CDS             6284..7222
                     /locus_tag="TV191_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEL1507413.1"
                     /translation="MKINQMKKDQPFEGFYLIKSAEVRKTRAGKDFIAFTFQDDTGEI
                     SGNLWDAQPYNVEEFVAGKIVFMKGRREVYNGTPQVNQITLRNIRPGEPNDPKEFKEK
                     APVSVTEVRDYLDQMLFKIENATWQRIVRALYRKYDKEFFTYPAAKTNHHAFESGLAY
                     HTATMVRLADSIGDIYPELNKSLLFAGIMLHDLAKVLELTGPDNTEYTIRGNLIGHIA
                     LINEEITKTITELNIDDNKEEVTVLRHVILSHHGQLEYGSPVRPRIMEAEIIHMIDNI
                     DANMMMMSTALSRIGEGEMTNRIFAMDNRSFYKPKY"
     gene            7322..8137
                     /gene="purR"
                     /locus_tag="TV191_000884"
     CDS             7322..8137
                     /gene="purR"
                     /locus_tag="TV191_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEL1507414.1"
                     /translation="MKLRRSERMVVISNYLINNPYKLTSLNTFATKYEAAKSSISEDI
                     AIIKKAFEESNIGEIDTLTGASGGVIFTPSISEAEARSIVEELCQRLSESNRILPGGY
                     IYLSDLLSTPKLLQNIGRIIANAFKGQKIDAVMTVATKGVPLANAVANILNVPFVIVR
                     RDLKITEGSTVSVNYASASSYRIEKMFLSKRSLKPNSRVLIVDDFLKGGGTITGMMSL
                     LTEFDSTLVGVAVFAENAQSEREQMSFKSLLKVSEIDVKNNRVVVEVGNIFDK"
     gene            8174..10678
                     /locus_tag="TV191_000885"
     CDS             8174..10678
                     /locus_tag="TV191_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC10/PgrA surface exclusion domain-containing
                     protein"
                     /protein_id="HEL1507415.1"
                     /translation="MEQENSRTKHVKSTIALTSTIALLGTSVGVSHQVKADDAKSGDA
                     NTSNTSEATLAKPETLEEAVLAVKATEETLSERKKELAETNTNIAETEGEIANLEATK
                     KEQIAELAKAEELLETYSSMSEEDLAKSIEKHETELETINTELEKATTESQAQAEAVA
                     KQQETIAAEATKADQLATQLTAAEQKVSDLNTMISQPEAIVSEAQAAKEEVKRISDDL
                     AKATANLATVKETVHSQLTSDLAANKAALAAKEAELQRLQNGVATAQLNVAGSNKLIL
                     PKDYPIEEIKKLAASGYIGTAAYNQYYQAVKDTMIAKAEPGAAMNQYVDIPEDLNRVV
                     DPDNLSQEVQNELAQFAAQMINDVRKQLGLVPVTVTVGSQEFARLLTKSYKETHQNTR
                     PSFVYGQVDASGHRGVGPHDQTIIEESAVKVGLRQKDDNMYENLGAFNEVHTVNGIKR
                     GIYDSIKYMLFTDHLHGNTYGHAVNFLRVDKTDPNAPVYLGFSTSNVESLNEHFVIFP
                     ESDIVDATRFSTTEIPKSGQVIDRSASIQALTNDIASIKGKIASLESRLADPSSEAEV
                     TAAQAKISQLQHQLEAAQAKSHKLDQQVEQLANTKDSLRTQLLAAKEEQAQLKANLDK
                     ALALLASSKATLHKLEAAMEEAKARVAGLASQKAQLEDLLAFEKNPNRIELAQEKVAA
                     AKKALADTEDKLLAAQASLSDLQAQRARLQLSIATIEQQLVLLKNLVQEKQRLRLEAE
                     RLNSMSETRQLLNQLAPQAAKAGVGSELVATGLLVSKVASAIAKQSPTSHSYGAGAAS
                     HAAVDDNTQRAVQAGMVMLAAAGLATVKLKKGSKKR"
     gene            10861..11274
                     /gene="rpsL"
                     /locus_tag="TV191_000886"
     CDS             10861..11274
                     /gene="rpsL"
                     /locus_tag="TV191_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEL1507416.1"
                     /translation="MPTINQLVRKPRKSKIEKSDSPALNIGYNSHKKVHTKLAAPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLIRGGRVKD
                     LPGVRYHIVRGALDTAGVADRKQGRSKYGAKRPKG"
     gene            11295..11765
                     /gene="rpsG"
                     /locus_tag="TV191_000887"
     CDS             11295..11765
                     /gene="rpsG"
                     /locus_tag="TV191_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEL1507417.1"
                     /translation="MSRKNRAPKREVLPDPLYNSKLVTRLINRIMLDGKRGTASSIVY
                     DAFSEIKEATGNDALEVFETAMDNIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTASRARGEHTMKDRLAKEIMDAANNTGASVKKREDTHKMAEANRAFAHFRW"
     gene            12308..14386
                     /gene="fusA"
                     /locus_tag="TV191_000888"
     CDS             12308..14386
                     /gene="fusA"
                     /locus_tag="TV191_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEL1507418.1"
                     /translation="MAREFSLAKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWDGHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVQTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPEEYLEQAQEYREKLIEAV
                     AETDEDLMMKYLEGEEITNEELVAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVIA
                     YLPSPLDIPAIKGVNPDTDAEEERPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     NSGSYVMNTSKGKRERIGRILQMHANSRQEIETVYAGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESIEVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIA
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLIESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLALKEAAKTAQPAILEPMMLVTITAPEDNLGDVMGHVTA
                     RRGRVDGMEAHGTSQIVRAYVPLAEMFGYATVLRSATQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGE"
     gene            14469..14621
                     /locus_tag="TV191_000889"
     CDS             14469..14621
                     /locus_tag="TV191_000889"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507419.1"
                     /translation="MTEKSSPIRHKRLGKGLKKALLTTLSDTFGCPKKLFAVSILMEK
                     QSFENG"
     gene            14767..15777
                     /gene="gap"
                     /locus_tag="TV191_000890"
     CDS             14767..15777
                     /gene="gap"
                     /locus_tag="TV191_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEL1507420.1"
                     /translation="MVVKVGINGFGRIGRLAFRLIQNVEGVEVTRINDLTDPAMLAYL
                     LKYDSTQGRFDGDVEVVEGGFNVNGKFVKVSAEANPENIDWASQEVDIVLEATGFFAS
                     KAGAEKHLHANGAKKVVITAPGGNDVKTVVFNTNHEILDGTETVISGASCTTNCLAPM
                     AKVLQDKFGVVEGLMTTIHGYTGDQMTLDAPHRKGDFRRARAAAVNIVPNSTGAAKAI
                     GLVIPELNGKLDGAAQRVPVPTGSVTELVSVLEKDVTADEVNAAMKAAANDSFGYTED
                     QIVSSDVVGIHYGSLFDATQTKVLTVDGKQLVKTVSWYDNEMSYTAQLVRTLEYFAKI
                     AK"
     gene            16321..17175
                     /locus_tag="TV191_000891"
     CDS             16321..17175
                     /locus_tag="TV191_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase, lipoprotein e(P4) family"
                     /protein_id="HEL1507421.1"
                     /translation="MTSKKILNLVSLGLSLVLISGCTTNGEKKAAPSQDKDKQEKVVR
                     LTNDQLRARENTMATLWYQQSEEAKALYLQGYQVAKQRLDTLLSQATDKPYSIVLDID
                     ETVLDNSPYQAKNIKEGTGFTPDSWDKWVQKKSAKAVAGAKDFLQYANDKGVQIYYVS
                     DRTTKQVEPTMENLEKEGIPVQGKDHFLFLEEGVKSKEGRRQKVQETTNLVLLFGDNL
                     LDFAEFSKTSHEDRRKLLDQLHAEFGSKFIIFPNPMYGSWESSVYNGQKLDSEGQIKA
                     RDKALEAY"
     gene            17385..18581
                     /locus_tag="TV191_000892"
     CDS             17385..18581
                     /locus_tag="TV191_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEL1507422.1"
                     /translation="MAKLTVKDLDLKGKKVLVRVDFNVPLKNGVITNDNRISAALPTI
                     KYIIEHGGRAILFSHLGRVKEEADKEGKSLAPVAKNLAEKLGQEVIFPGSTRGAELEA
                     AIDALEDGQVLLVENTRFEDIDGKKESKNDPELGKYWASLGEGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIKEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYEAQGIEIGNSLCEEDKLDVAKSLLEKSNGKLVLPVDSKEANAF
                     ADYTEVKVTEGEAVDTGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQEG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKELPGL
                     AALTEK"
     gene            19004..19525
                     /locus_tag="TV191_000893"
     CDS             19004..19525
                     /locus_tag="TV191_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEL1507423.1"
                     /translation="MNYHFDASKLKLGMRTFKTGLAVFFVLLLFHFFDFQGLQIGALT
                     AVFSLRESFDKTISFGTSRILGNSIGGFFAIIFYLLDTLFQGAFWVTLVFVPILTMLT
                     IMFNVAFNNQSGIIGAVAALLIITLSIPTGEAFMYVIARVFETFCGVFIAILVNTDVE
                     LIRNKWLSRKLKK"
     gene            19601..19972
                     /locus_tag="TV191_000894"
     CDS             19601..19972
                     /locus_tag="TV191_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEL1507424.1"
                     /translation="MKEKELRRSMAVFPIGAVMTLTDLSARQIRYYEDQELIKPERTE
                     GNRRLFSLNDMDRLLEIKDFLDEGLNIAAIKREYAERQDKLMQKQKVLTDADVRRILH
                     DELLNQGGFSTPSQHIGNFRI"
     gene            20009..21355
                     /gene="glnA"
                     /locus_tag="TV191_000895"
     CDS             20009..21355
                     /gene="glnA"
                     /locus_tag="TV191_000895"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEL1507425.1"
                     /translation="MAITAADVRREVKEKHVTFLRLMFTDIMGVMKNVEIPATEEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWIVFPWGDENGTVGGLICDIYTAEG
                     KPFAGDPRGNLKRALKHMDEVGYQSFNLGPEPEFFLFKIDEAGEPTLEVNDKGGYFDL
                     APIDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYADALKACDNIQIFKLV
                     VKTIAREHGLYATFMAKPKFGIAGSGMHCNMSLFDKGGNNAFYDENDKRGMKLSDDAY
                     YFLGGLMKHAYNYTAITNPTVNSYKRLVPGYEAPVYVAWAGSNRSPLIRVPASRGMGT
                     RLELRSVDPTANPYLALAVLLEAGLDGIINKIEAPAPIEANIYMMTAEERNAAGIVDL
                     PSTLHNALKALQKDEVIQKALGDHIYTNFLEAKRIEWSSYATFVSQWEIDNYLHNY"
BASE COUNT         6262 a         4115 c         5013 g         6063 t
ORIGIN      
        1 attacagtta tgtcaaggct gactgtttga gtaaaccaag agctatgcta agaatgaagt
       61 agctgatgag atatggtata ataatcaagc aggtatccct tttagggcaa tacaagaaag
      121 aggaatgact aagaatgata gaaatttttg atacccatac gcatttgaat gtggatcatt
      181 ttagtggtaa agaggaagag gaattagcac ttgctaagga gtttggggtt agctaccata
      241 atgtcgttgg ctttgatcag gagactattg atcaagccct taccttagct gatgcttata
      301 gggaggtcta tgcaacgatt ggctggcacc cgactgaggc tggctcttac acacaggcgg
      361 ttgaagatag tctgattgct tgcttgaagc acccaaaggt tgttgcctta ggagagattg
      421 gcttggatta ctattggatg gaggacccca aggaggtaca gatagaggtc tttaagcggc
      481 agctacagct tgctaaggac catgacctcc cctttgtggt gcatacgcgt gatgcccttg
      541 aggataccta tcaggtctta aaggaggctg gagtgggtcc tagaggtggt atcatgcatt
      601 cttactcagg atcacttgag atggctcaac gatttgtaga tctgggtatg ctgatttcct
      661 tttcaggggt tgtcaccttt aaaaaggcgg ttgatgttca ggaagcagca agacacctgc
      721 cgctggataa gctcttggtg gaaacagatg ccccctacct cgccccagta ccaaagagag
      781 gacgtgaaaa ccataccgcc tatacgcgtt atgttgttga gaaaatcgcg gagctacgtg
      841 gtttatcagt agaagagata gctgcagcaa cgactgccaa tgcaaagagg gtgtttagaa
      901 ttgactgaga agcttaaaat tcaagaggtt attgtggtag aggggaagga cgataccgct
      961 aatttacagc gcttctatga tgtcgatacc tatgaaacaa agggctctgc catcactgat
     1021 gaggacttag aacgcattga tcggcttaac aagctgcgtg gtgtgattgt ctttacggat
     1081 ccagattatc atggcgagag gattcgcaaa ctgattatga gagctgtccc aacagctcgt
     1141 catgcctttt tacgtcgaca tgaggctaag ccaaggtcca aaagtaaggg acgttcctta
     1201 ggtgtggagc acgctagctt tgaggacctg caaaaggctc tgtctcaggt tacccagtct
     1261 tttgatgacg agagttattt tgatattagt cagacagatt tgattcgtct agggctttta
     1321 ttggcagctg atagccgcaa gcgcagagag tatctaggag aagtccttcg tatcggctat
     1381 tccaacggaa agcagctcct aaagcgccta aagctatttg gcattaccct atcagaggtt
     1441 gaggacgtga tgacctccta tcagactgag caatagatgg cgctagaaag gctgattgga
     1501 tcaaacaaaa gagccctgag acttcttgtt ctggctccaa aaaattagat aagaaatggt
     1561 aacaaggatt gaattctgta ttgggcagga gtcagtcctt ttaactttct tagataagca
     1621 ttctctgttc taagacgttc attctccttg aagttgctct agttctccag atgttctttg
     1681 attgatgtcc tctcttgctt ggtttccctc ttgttttatc aagaatagta taaccatttt
     1741 catctctttt tttgctgtgg ctctgataaa taatagaaat atgctacaat agatataaaa
     1801 caatgaatag gacatcaaca tgagaattgc agattacagt gtaaccaagt ctatccttga
     1861 tcgctatggt tttaccttta aaaaatcatt tggtcaaaat ttcttgacgg atactaatat
     1921 tttacagaag attgttgata cggctgagat tgacaagtca gtcaacgtca ttgagattgg
     1981 tcctggtatc ggggctttga ccgaattttt ggcagaaagg gctgcagagg tcatggcctt
     2041 tgagattgat gagcgcttgg tgccaatact ggctgatacg cttcgtgatt ttgacaatgt
     2101 tcaggtggtt aatcaggata ttttaaaggc agatttacag acccagctaa agcaatttag
     2161 caatccggac cttcctatca aggtggtagc caatttgccc tattacatca ctacacccat
     2221 tttgatgcac ctgattgaaa gtaagattcc cttccaagaa tttgtcgtca tgatgcagcg
     2281 cgaggtggca gatcggattt cagctgagcc caataccaag gcctatggct ctttgtctat
     2341 agcagtccag tattatatga ccgctaagat agcctttgtt gttcctagga ctgtttttgt
     2401 gccagcacca aatgtggatt cggcaattct gaagatgact cgtcgtgacc agcccttgat
     2461 tgaggttcaa gatgaggatt tcttttttag ggtgtcacga gtaggctttg tgcatcgcag
     2521 aaagacgctt tggaataact tggttagcca ttttggcaag gctgaggaca caaaggcaag
     2581 gcttgagcag ggactagctc tagctggaat caagccttct atccgaggag aagcgctgtc
     2641 tattcaagat tttggacggt tagctgatgc cctaaagcaa gtaggcttct agtgccttag
     2701 ttatgattgt agcttgtcac agcaatcctg ctgtggcttt tttagatagt ggtgggttca
     2761 tcttatcttt ggtgaaactt gggctaaact gctgaattcg aatgattttt ctgatataat
     2821 ggcattattc taggataaaa aaaggagttc atttgcaagg caaaatcatt aaggctctgg
     2881 ctggctttta ctatgttgag tcagaggggc aggtttatca aacgcgggcg cgtggcaatt
     2941 ttagaaagcg tggtcaaaca ccctatgtag gagatttagt agaattttct gctgaggaca
     3001 attcagaggg ctatatttta gctattgctg agcggaaaaa tagtctggtg cgtcctccca
     3061 ttgtcaatat tgatcaagca gctgtcatta tgtcagccaa ggagcctgat tttaatacca
     3121 accttttaga tcgctttctc attttacttg agcacaaggc catccaccct attatttaca
     3181 tttcaaaaat agacctgctt gagcagccag agagtatcga agccattggt cagcattatc
     3241 gtgcgattgg ctatgatttt gtgacgagct tatcacatct gctgccatta ttagctggta
     3301 agacaacagt atttatgggg cagacaggag ttggaaagtc cactttgcta aaccgtatcg
     3361 caccagagct agctcttgaa acgggtgata tttcagacag tctgggacga ggacgccaca
     3421 ccactagagc tgttagcttt tatgacgctt ataatggcaa aatcgcagac acccccggct
     3481 tttcgtcctt ggactatggc attgataatg ctgaggatct caacgaagcc tttccagagc
     3541 ttagacgcct tagccatagc tgtaaatttc gctcctgtac ccatactcat gagcccaagt
     3601 gtgcggttaa ggaagccttg ggaaatggtg agctctggtc tgttcgctat cagaattacc
     3661 ttcaatttct gagtgaaatc gaaaaccgtc gagaaacata tcaaaaagtt agtaaaagaa
     3721 agtaggttta actatgtcat ctctgaaaat tgcgccatct attttagcag ccgattatgc
     3781 ttgctttgct gctgagctgg ctcgtattga aaaaacagat gctgaatacg ttcatattga
     3841 tatcatggac ggtcagtttg tgccaaatat cagctttgga gcagatgttg ttgctagcat
     3901 gcgcaagcac agcaagctag tctttgattg ccacttgatg gttgtgaatc ctgagagata
     3961 tgttgaggcc tttgctcagg caggagctga tatcatgacc attcatgtgg agagcactct
     4021 tcatagtcat ggcgccttgc aaaagatcag ggctgccggc atgaaggctg gtgtggtcat
     4081 taatcctggg acacctgtct ctgcggttga gcctttatta agcttggtgg atcaggtgct
     4141 gatcatgact gttaacccag gctttggagg acaggccttt attccggaat gtctggaaaa
     4201 ggttgcagct attgctaaaa tgagagatga aagaggcttg agctttgata ttgaggttga
     4261 cggtggtgtt gatgataaaa ccattcgtgc ttgctatcaa gcaggagcta atgtttttgt
     4321 ggctggctcc tatctgttta aggcagcgga tttggcagct caagtgcaaa cattgagggc
     4381 ggcccttaat ggttaaggta gccctctttg caggtgggga tttgtcctat tttacctgtg
     4441 attttgatta ttttgttgga attgatagag gaagtctatt tttgttagaa aatgggcttc
     4501 ctttgaatat ggctgtaggc gattttgatt caattcccca agtagccttt gaggttgtca
     4561 aggagcaagc agagcttctt gttcaggcta gtcctgaaaa aaatgatacg gacactgaat
     4621 tagctctcaa agaggtattt acccgttttc cagaggcaga ggttacgatc tttggtgctt
     4681 ttggcggtag actagaccac ttgttatcca atgtcttttt accagcggat ccagagcttg
     4741 caccgtttat ggcacaaatt tgcctgcggg atcagcaaaa tgccattagc tatcgatcct
     4801 ctggctggca gacgattagg caggataagg acatgactta tgtggccttt atggctgatg
     4861 gtgatgctga cttgaccatt acaggtgcca aatttgattt gacgacgtcc aatttcttta
     4921 agaaaaaggt atacgctagc aacgagttca ttgatcagcc tattaaggtt catgtgccaa
     4981 agggctattt aattattatt cagagcaaag ataggagtta gtatggacct tattcttttc
     5041 gtgttagtgc ttgtgttgat aggacttgct gcctattcat ttgttagcat aaagcatttg
     5101 cagagcagat tagaaaaagc cttagacgat aatgctgata atctatcaga tcagctaacc
     5161 taccagctgg atatggcaaa taagagtcag ctgctagagc tatcaacagt gatgaatcgt
     5221 cagcaaaatg agctttttca gcagctgatg gttattcgtg atacgctgca tcagggcttg
     5281 gctgaaaatc gcgaccgctc agaccagcgt ttggaaacga tgactcaaag ccttagccaa
     5341 gctgtcaaga acctacagga ttctaatgaa aagcgactgg aggaaatgcg ccatacagtc
     5401 gaagaaaagc tagaaaagac attgaagaat cgattgcaaa cctcctttga ggccgtttca
     5461 aagcagctag aaagcgtcaa tcagggtcta ggagaaatgc ggaccgtagc caaagatgtt
     5521 ggtaccctaa acaaggtcct atccaatacc aaaaccagag gaatcctagg tgagctccag
     5581 cttggtcaga ttgttgagga catcatgaca gctaaccagt atgaaagaga gtttgccaca
     5641 gtttctggct caagcgatcg tgtcgaatac gctatcaagc tacctggaaa tgggcaagga
     5701 gactatattt acctacctat tgactccaag tttcccttgg aggattatta caggctggag
     5761 gacgcctacg aggctggtga tagagctgct attgagacta gccgaaaggc tcttcttgcg
     5821 gcgattaaac gttttgctaa gagtattcat agtaaatacc tgaatccacc tgaaacaacc
     5881 aattttggga ttatgttttt accaaccgag gggctctact cggaggtggt gcgcaatccg
     5941 gctttctttg atagccttcg tcgcgaggaa aatattgttg tagcaggccc atcaacctta
     6001 tcagccctgc ttaattcctt atctgttggc tttaaaaccc ttaacctgca aaaaaacgca
     6061 gacgatatta gcaagatttt aggcaatgtc aaattagaat ttgaaaaatt tggcggcctg
     6121 cttgctaagg cgcaaaagca gctcaacact gctaaccata ccctagacca gctgatgtca
     6181 accagaacca aagcgattgt tcgtgctctg gctactgtcg aaggctacca agaccagtca
     6241 acccaatcct tattacatat acccttatta gaagaggcag acgatgaaga ttaaccaaat
     6301 gaaaaaagac cagccttttg aaggctttta cctgataaaa tcagcagaag tcagaaaaac
     6361 aagggctggc aaggatttta ttgcttttac ctttcaagat gatactggtg agatttcagg
     6421 taatttgtgg gacgcccagc cctataatgt tgaggaattt gtcgcaggta agattgtctt
     6481 tatgaaaggc cgtcgtgagg tctataatgg cactcctcag gttaaccaga ttaccttaag
     6541 aaatatccgg cctggggagc ctaatgaccc aaaggaattt aaagaaaagg cacctgtcag
     6601 tgttactgag gttcgtgact acctagatca gatgctcttt aagatcgaaa atgcgacctg
     6661 gcagaggatt gtcagagcgc tttaccgcaa atatgataag gagtttttca cttatccagc
     6721 agccaaaacc aatcaccatg cctttgaatc aggcttggcc tatcatacag caacgatggt
     6781 tagactagca gatagcattg gagatattta tccagagcta aataaaagcc tgttatttgc
     6841 aggcattatg ctgcatgacc tagccaaggt acttgagctg acaggcccag acaataccga
     6901 atatactatc cgaggcaatc tgataggaca tatcgccctc atcaacgaag agattacaaa
     6961 gaccatcaca gagctgaaca ttgatgacaa caaagaagag gtcaccgttt tacgccatgt
     7021 aatcttaagt catcatggcc aattagaata cggcagccct gttcgtccgc gcattatgga
     7081 ggcagagatt attcacatga ttgacaacat tgacgccaat atgatgatga tgtcaacagc
     7141 tctcagtcgt attggcgagg gagaaatgac caatcgtatt ttcgctatgg ataaccgatc
     7201 cttttataaa cctaaatatt agcaaggatc ataataaaaa acgaacattt tgcagttgaa
     7261 tgttcgtttt ttcgttatgt tatgatataa tagtagagaa tatataaata atggggaaca
     7321 tatgaaatta agacgaagtg aacgcatggt tgtgatatct aattacctga ttaacaaccc
     7381 ttataagcta acaagtttaa atacctttgc cacaaaatat gaggcagcca aatcatctat
     7441 ttcagaagat attgccatta tcaaaaaagc ctttgaagaa tctaatattg gagagattga
     7501 cactctaaca ggggcaagtg gaggtgtcat ttttacgcca agcatttcag aggcagaggc
     7561 tcgctcaatc gtagaagagc tgtgtcagcg gctttcagaa agtaaccgca ttttacctgg
     7621 tggctatatc tatctgtctg atttattaag cacaccaaag ctcttgcaga atatcggtcg
     7681 cattatcgct aatgctttta aggggcaaaa aattgacgcg gtgatgacag ttgcaactaa
     7741 gggggttccc ttggctaatg cggttgcaaa tattctgaat gtaccctttg tgattgtcag
     7801 gcgcgactta aaaatcacag aaggttcaac cgtctcagtc aactacgcta gtgcctcaag
     7861 ttatcgtatt gaaaaaatgt ttttatcaaa gcgaagctta aagccaaaca gtcgagtctt
     7921 gattgttgat gattttttaa agggtggtgg tacaatcaca ggcatgatga gcctgttaac
     7981 ggagtttgat agtacattgg tgggtgtagc tgtttttgca gaaaatgcac aatcagagcg
     8041 cgaacaaatg tccttcaagt cactattaaa ggtctccgaa attgatgtca aaaataatag
     8101 ggtcgttgtt gaagtaggaa atattttcga taaataaatc gaacgtaggt ggaaaaataa
     8161 aaggggatta atcatggagc aagaaaactc aagaacaaag catgttaaaa gtaccattgc
     8221 tttgacatca accattgccc tattagggac aagcgttggt gtatcacatc aggtaaaggc
     8281 agacgatgct aagtcaggcg atgccaatac aagcaatacc agcgaagcta cgctagctaa
     8341 gccagaaacg cttgaggagg cagtccttgc ggtaaaggct acagaagaaa cactcagtga
     8401 gcgtaaaaaa gaattagctg agactaatac aaatatcgcg gaaacagagg gcgaaatcgc
     8461 aaacctagaa gcaactaaaa aagaacagat agctgagctt gccaaggctg aggagctact
     8521 tgagacttac tcgtccatga gtgaggaaga cctagccaag tcaattgaaa agcatgagac
     8581 agagctagag acaattaaca cagaactaga gaaggcgact actgagagtc aagctcaggc
     8641 agaggcagtg gctaagcagc aagaaacgat cgcagcagag gctacaaagg ccgaccagct
     8701 agctacccag ctaacagcag cagagcaaaa ggtctcagac cttaacacga tgattagcca
     8761 gccggaagct attgtctcag aagctcaagc tgcaaaagaa gaggtcaagc gcatttctga
     8821 tgacctagca aaggctacag caaatctagc tactgttaag gagacagtcc acagccagct
     8881 aacctcagac ctagcagcca acaaggcagc cctggcagct aaagaggcag agctgcaaag
     8941 gcttcaaaat ggagttgcca ctgcccaatt gaacgttgct ggcagcaata aattaattct
     9001 tccaaaagac tacccaattg aggagattaa aaagctagca gccagtggtt atatcggaac
     9061 agcagcatat aatcaatatt atcaggcagt taaggataca atgattgcaa aggcagagcc
     9121 gggtgctgcc atgaatcagt atgttgatat tcctgaggac ctcaatcgtg ttgttgaccc
     9181 tgacaaccta tcacaagagg ttcaaaatga gctagctcag tttgcagctc aaatgattaa
     9241 tgatgtccgc aagcagctag gacttgtccc tgtaacagta acagtcggct cacaggagtt
     9301 tgctcgcctg ctaaccaaga gctacaagga aacacatcaa aatactcgac cttcctttgt
     9361 ctatggacaa gtagatgctt caggtcatcg cggtgtaggt ccgcatgatc aaacgattat
     9421 tgaagaatct gctgtaaagg taggacttcg tcaaaaagat gacaacatgt acgaaaacct
     9481 tggtgccttt aacgaggttc acactgtcaa cggtatcaag cgcggcatct atgacagcat
     9541 taagtatatg ctgtttacag atcacctgca tgggaacacc tatggtcatg ctgttaactt
     9601 cctgcgtgtt gataagactg accctaatgc acctgtttac ctaggatttt caacaagtaa
     9661 tgttgagtcc ttaaatgagc attttgtgat tttcccagag tcagatattg tggacgctac
     9721 tcgttttagc acgactgaaa ttccaaaatc aggtcaggtg attgatcgct cagcaagcat
     9781 acaggcattg acaaatgata ttgcttcgat caagggcaag attgcgtctc ttgaaagcag
     9841 attagctgat ccttcctcag aagctgaggt cacagctgcg caggcaaaaa tcagtcagct
     9901 gcaacatcag ctagaagcag cccaagccaa atctcataaa ttggatcaac aggttgagca
     9961 attggccaat acaaaagatt ctctacgcac acagttgctt gctgccaaag aagagcaggc
    10021 acaattgaag gctaatctag ataaggcctt ggccttgcta gcgtcttcaa aggctacgct
    10081 tcataagctt gaagcagcta tggaagaggc taaggcaaga gtagccggct tagctagtca
    10141 gaaggctcag cttgaggatc tgctagcctt tgagaaaaat cctaatcgga tcgagcttgc
    10201 acaggaaaag gtagccgcag ccaaaaaggc tttagctgat acagaggata agctcttagc
    10261 tgctcaggcc agcctgtctg atttgcaggc tcaaagagca agactccagc tttctattgc
    10321 gacaattgaa caacaattag tactattgaa gaatttagtc caagaaaagc aaaggctcag
    10381 acttgaggct gaaaggctaa atagcatgtc agaaacaaga cagcttctca atcagctagc
    10441 gccgcaggct gcaaaagcag gtgtcggctc agaattggtt gctacaggtc ttcttgtctc
    10501 caaggttgcc tcagctatcg ctaagcaatc accgacaagc cattcctatg gagcaggagc
    10561 agcatcacat gcagctgttg atgacaacac acagcgtgct gttcaggctg gtatggtcat
    10621 gctggcagct gccggcttag caacggttaa gctcaaaaaa ggcagcaaaa aacgctaagc
    10681 ctagcttaaa aagcatttga cacaaggtat cgtctatgtt attatattag acggtacttt
    10741 ttacttttgg tctctcaaga gtgtacagag acgtgctgac aattgttgca aaaagtgcac
    10801 cagatatagg ctgtcaccaa gtgctatatc aaccaaaatt aaaaaaacag gagaatgtag
    10861 atgcctacaa ttaaccagtt ggtacgtaaa ccacgtaaat ctaaaattga gaaatcagat
    10921 tcgccagctt tgaacattgg ctacaacagt cataaaaaag ttcatacgaa gcttgctgct
    10981 ccacaaaagc gtggtgttgc gactcgtgtt ggaacaatga cacctaaaaa acctaactca
    11041 gcccttcgta aatttgcgcg tgtacgctta agcaacctta tcgaagtaac agcttatatc
    11101 ccaggtattg gccacaacct acaagagcac agtgttgtgc ttatccgcgg tggacgtgta
    11161 aaggaccttc caggggtacg ctatcatatc gttcgtggag cacttgatac tgcaggtgtt
    11221 gcagaccgta agcaaggccg ttctaagtac ggtgctaaac gtccaaaagg ataatagagg
    11281 agggataaga aacaatgagt cgtaaaaata gagcgccaaa acgcgaagta ttaccagatc
    11341 cattatataa ctcaaagctt gtgacgcgtc ttatcaatcg tattatgctt gatggaaaac
    11401 gcggaactgc atcatcaatc gtttatgatg cttttagcga aatcaaagaa gcaacaggca
    11461 acgatgctct tgaagtattt gaaacagcta tggacaacat catgcctgtg cttgaagtgc
    11521 gtgcacgtcg tgtcggtggt tcaaactatc aggttccagt tgaggttcgt ccagagcgtc
    11581 gtacaacact tggtcttcgt tggttggtaa ctgcatcacg tgctcgtggt gaacacacta
    11641 tgaaagatcg tcttgctaaa gagattatgg atgctgcaaa caacaccggt gcgtcagtca
    11701 agaaacgtga ggatactcat aagatggctg aggctaaccg cgcctttgca cacttccgtt
    11761 ggtaagaata agatacgaag gtgtacagaa cgcatagtga agataggaag cttgacgaag
    11821 agatttttat ctctaggaaa gcttatcttt ttcacacagc gtttagcctg agttcagttt
    11881 taggctgttt tagtgtgaga caaatgctag cccaaatcgg gaaattgacg cagaagcgat
    11941 catttccaga agattttatc tttttggcag acatttgtcg ctaaaattca actaatctaa
    12001 gatgtgagag tgttaagcaa gttctagaca aactgatcta ttatcttttt tgtcagtgac
    12061 ttgcagctca aactcagtta caatcaagat gtatagacaa agagagcaag attttaatag
    12121 aaaattctca ccttcaagat gagttattgt tttgatcgga ttgctcttaa gtcgggtttt
    12181 ggtttgcaaa catactaaat gctatctatc aaacatatct taggaaacgg gtaggcctct
    12241 gcctatccgt ttttaatgaa tagtgttata ataagatgta aataaaaaat ataggagaaa
    12301 aaacctaatg gctcgcgaat tttcactagc aaaaactcgt aatatcggta tcatggctca
    12361 cgttgatgct ggtaagacaa ctacaacaga gcgtatcctt tactacaccg gtaaaatcca
    12421 taaaatcggt gaaacacacg agggtgcatc acaaatggac tggatggagc aagagcaaga
    12481 gcgtgggatc acaatcacat ctgctgctac aacagcgcaa tgggatggac atcgtgttaa
    12541 tatcattgac acaccagggc acgtggactt caccattgaa gtacaacgtt cgctccgcgt
    12601 tcttgacggt gcagtaaccg ttcttgactc acaatcaggt gttgagcctc aaacagaaac
    12661 tgtttggcgt caagcaactg aatacggtgt tccacgtatt gtttttgcca acaagatgga
    12721 taagatcggt gctgacttcc tttactcagt acaaaccctt cacgatcgtc ttcaagcaaa
    12781 tgctcaccca attcaattac caatcggttc agaagatgat tttcgtggta tcattgactt
    12841 gatcaaaatg aaggctgaaa tctacaccaa tgaccttggt acagatattc ttgaagaaga
    12901 tattcctgag gaatacctag agcaagctca agaatatcgt gaaaagctta tcgaagcagt
    12961 tgctgaaact gacgaagatt tgatgatgaa ataccttgaa ggtgaagaaa tcactaacga
    13021 agaacttgtt gctggtatcc gtaaagcaac gatcaacgtt gagttcttcc cagtgctttg
    13081 tggctctgcc ttcaaaaaca aaggagttca attgatgctt gatgcggtta ttgcatacct
    13141 tccaagccca cttgacattc cagcaattaa aggggttaat cctgatactg acgctgaaga
    13201 agagcgtcca gcatctgatg aagagccatt tgcagccctt gccttcaaga tcatgactga
    13261 tccatttgta ggtcgtttga ccttcttccg cgtttactct ggtgttctta acagtggttc
    13321 atacgtgatg aatacctcaa aaggtaagcg tgagcgtatc ggacgtatcc ttcaaatgca
    13381 cgctaacagc cgtcaagaaa ttgaaacagt ttacgctggt gacattgctg ctgctgttgg
    13441 tttgaaagac actacaactg gtgactcatt gactgatgaa aaagcaaaaa tcattcttga
    13501 gtctattgag gttccagagc cagttatcca attgatggta gagcctaagt ctaaggctga
    13561 ccaagataag atgggtattg ctcttcaaaa gcttgctgaa gaagatccaa ccttccgcgt
    13621 tgagacaaac gttgagactg gtgaaacagt tatcgctggt atgggtgagc ttcaccttga
    13681 tgtccttgta gaccgtatgc gtcgtgaatt caaggttgaa gctaatgtag gtgctcctca
    13741 ggtatcttat cgtgaaacct tccgcgcttc tacacaggct cgtggcttct tcaagcgtca
    13801 gtctggtggt aagggtcaat tcggtgacgt ttggattgaa tttacgccaa atgaagaagg
    13861 taaaggattt gagtttgaaa atgccattgt cggtggtgtg gttcctcgtg aatttatccc
    13921 agccgttgaa aaaggcttga ttgagtctat ggctaatggt gtccttgcag gatacccaat
    13981 ggttgacgtt aaagctaagc tttacgatgg ttcataccat gatgtcgact catctgagac
    14041 tgccttcaag attgcggctt cacttgccct taaagaagca gctaaaacag cacagccagc
    14101 tatccttgag ccaatgatgc ttgttacaat cacagctcca gaggataatc ttggagatgt
    14161 tatgggacat gtgacagctc gtcgtggacg tgttgatggt atggaagcac atggtactag
    14221 ccaaattgtt cgtgcttatg tgccacttgc agaaatgttt ggttatgcga ctgttcttcg
    14281 ttctgcaacg caaggacgtg gtacattcat gatggtattt gaccactatg aggatgttcc
    14341 taagtcggtt caagaagaaa ttatcaagaa aaataaaggt gaataatcac ccctaagagg
    14401 ctgtggatag tatcccagcc tttttgatgt gttacaacag atgggcggtg cagcaattga
    14461 tcaaagcaat gacagaaaaa tcaagcccta tcaggcataa acgtttagga aaaggcctta
    14521 agaaagcgct tttaacaaca ttaagcgaca cttttggctg ccctaaaaag ctctttgctg
    14581 tctcaatatt gatggagaag cagtcttttg aaaatgggta atatgtttgc attttttctg
    14641 aaatagttat ataatagtta cgttgaaggg ttgttgcagg aatctgcaag ttaatctttt
    14701 cacaataggt agggattagt ccctttaata ataattcttt tgattttcat aaggaggaaa
    14761 tcactaatgg tagttaaagt tggtattaac ggtttcggtc gtatcggtcg tcttgcgttc
    14821 cgtcttatcc aaaatgtaga aggtgttgaa gtaactcgca tcaacgactt gacagatcca
    14881 gccatgttag catatctttt aaaatatgat tcaactcaag gacgctttga tggcgacgtt
    14941 gaagtagtag aaggtggatt taacgttaac ggtaaatttg ttaaggtttc tgctgaagct
    15001 aaccctgaaa acattgactg ggcttcacaa gaagtagata tcgttttgga agcaactggt
    15061 ttcttcgctt caaaagctgg tgctgaaaag cacttacacg ctaatggtgc taagaaggtt
    15121 gttatcactg ctcctggtgg aaacgatgtt aaaactgttg ttttcaacac taaccacgaa
    15181 attcttgatg gtactgaaac agttatctca ggtgcttcat gtacaactaa ctgtcttgcc
    15241 ccaatggcta aagttcttca agacaaattt ggtgttgttg aaggcttgat gacaactatc
    15301 catggttaca ctggtgacca aatgactctt gatgcaccac accgtaaggg tgatttccgt
    15361 cgtgcacgtg ctgcagctgt gaacattgtt cctaactcaa ctggtgctgc aaaagctatc
    15421 ggtcttgtta ttccagagct taacggtaag cttgacggtg ctgcacaacg tgttccagtt
    15481 ccaacaggat ctgttactga gttagtatct gtacttgaaa aagacgttac agctgacgaa
    15541 gtgaatgctg caatgaaggc tgctgcaaac gacagttttg gttacactga agatcaaatc
    15601 gtatcaagcg acgttgtagg tatccactat ggttcattgt ttgatgcaac tcaaactaag
    15661 gtattgacag ttgatggtaa acaattggtt aaaactgttt catggtatga caacgaaatg
    15721 tcatacactg ctcagcttgt tcgtacactt gagtactttg caaaaattgc taaataatga
    15781 ctagagggcc tagtttacct aggctctttt ttgtgtcatg ataaaggttg cttatccctc
    15841 attggctagc ttattgctga acttgcactt aggcttaagc tgcacatagg ataagttttt
    15901 ttgctaacgc tttagtgatt agctgttctc agagagggtc attttagaaa ccttcttaag
    15961 gtgatatggc tatcaagctg ccttctttga actgctatgc ttaggctttg agtttaggtc
    16021 ttaaaagctt taggtgagtt tttcgttata attaactgca taaagcatgg ctttaagctc
    16081 atttccagcg caaatacctt ttttctttgc aagatgtcaa agagaagtac tgtaatggct
    16141 cgggcttatc tacatttttt gctcagctat ttttagctgt tttttagcta tggctccatg
    16201 aaattgtgaa gcgttttcat ttttattggt tatagtcttg acaatctgaa atgatggtaa
    16261 taaaatgaga ggtggataaa taaccgtact taataatgta tggaatatta ggaggatttt
    16321 atgacatcta aaaaaattct taaccttgtg tctttagggt tatcgttggt tttaatctct
    16381 ggctgtacga caaatggaga gaaaaaagca gctcctagtc aagacaagga taagcaagaa
    16441 aaggttgtcc gtctaaccaa tgatcagcta agggctaggg aaaataccat ggccacactc
    16501 tggtatcagc agtctgaaga ggctaaggct ctctacttac aggggtacca agtggctaag
    16561 cagcgcttag atacattatt gagtcaagca actgataaac catactctat tgttttggac
    16621 attgatgaga cagtgctcga taatagtcct taccaggcta aaaatattaa agagggcaca
    16681 ggctttacgc cggattcttg ggataaatgg gtccaaaaga aatcagccaa ggcagtagca
    16741 ggtgctaagg acttcttgca gtatgcaaat gacaagggcg ttcagattta ctatgtttct
    16801 gacagaacga ctaagcaagt agagccgact atggaaaatc ttgaaaaaga aggtattcca
    16861 gtgcaaggca aggatcattt cttgttctta gaggagggtg taaaatcaaa agagggccgt
    16921 cgtcaaaagg tgcaagaaac aacaaatcta gtgttgttat ttggtgacaa tttgcttgat
    16981 tttgcagagt tttctaagac ctctcatgaa gatagaagaa agcttttgga tcagctgcat
    17041 gcagagtttg gcagcaagtt tatcatcttc cctaatccaa tgtatggatc atgggaaagc
    17101 agtgtctata atggtcaaaa attagacagt gaaggccaaa tcaaagcacg tgacaaggct
    17161 ttagaggctt attaaaagcc ctgatttgcg tgattgctat gactatgttg tggcttcctg
    17221 cctgcttagg tgattgtgat ctgctaaaaa gaggtttacc caagggattt ttcaagcgct
    17281 ttgaaaaatt gtgaaatagt taatttattg ttttcagatt ttatccttat caaaagaatt
    17341 gtgttataat agagtgtact aaaaaatatt aaggagtcta tgaaatggct aaattgactg
    17401 ttaaagacct tgacctaaag ggtaaaaaag tgctcgttcg cgttgacttt aatgtccctt
    17461 tgaaaaatgg tgttattaca aacgataacc gtatttctgc agcacttcca acaatcaaat
    17521 acattattga gcatggtggt cgcgctatcc ttttctcaca cctaggacgt gtgaaggaag
    17581 aggcagacaa ggaaggcaaa tcattggcgc cagtagcgaa aaacttggct gaaaagcttg
    17641 gtcaagaggt tattttccct ggtagcactc gtggggcaga gcttgaagct gctattgatg
    17701 ctcttgagga tggacaggtt cttttggttg aaaacactcg ctttgaggat attgacggta
    17761 aaaaggaatc taaaaacgat ccagagcttg gtaaatactg ggcatcacta ggagaaggaa
    17821 tctttgttaa tgatgccttt ggtacagctc accgcgctca tgcgtcaaac gttggtatct
    17881 ctgcaaatgt tgaaaaagca gtggctggtt tccttcttga aaatgaaatt gcctatatca
    17941 aggaagctgt tgagactcca gagcgtccat ttgtcgctat tcttggtggt tcaaaggttt
    18001 ctgataagat cggtgtgatt gaaaaccttc ttgaaaaagc tgataaggtg cttatcggtg
    18061 gtggtatgac ctataccttc tacgaagctc aaggtattga aattggaaac tcactttgtg
    18121 aagaggacaa gcttgatgtg gcaaaatcac ttcttgaaaa atcaaatggc aagcttgttt
    18181 taccagttga ttccaaagaa gcaaacgctt ttgcagatta cactgaagtg aaggtaactg
    18241 agggtgaagc agttgataca ggcttccttg gtcttgacat cggtccaaaa tctatcgcta
    18301 aatttgatga agccctgaca ggtgctaaaa cagttgtttg gaatggtcct atgggtgtct
    18361 ttgaaaaccc tgatttccaa gaaggtacaa ttggtgtgat ggacgctatt gtgaagcagc
    18421 caggtgttaa gtcaatcatc ggtggaggtg attcagcagc ggcagccatc aaccttggac
    18481 gtgcagataa attctcatgg attagtacag gtggaggtgc ttcaatggag cttcttgaag
    18541 gtaaggagct tccaggctta gcagctctta cagaaaaata agctgatacc atttcggtgc
    18601 tgtcagtcgc aggctgctat atggtctgtt aagggctaag acagctgaag gctcacaaag
    18661 gtggcttatg ttgctggcgg tgcttatgct aattgttatg attaacaagc tgtcaaagga
    18721 taggctagag cctgctgtac cagtctatca ggccttgctg tcagctacta aatgaatgag
    18781 tcagaaaaag gtgctatgta ggtgcctttt tctgcgtttt gctttaggct gatagtgagt
    18841 ttgcttgaag tcaagactgg cttcatgcag gcttcagagt ctttgctagg aatgctataa
    18901 ggtgggttct gagcttatct atttaggata tgtgacaaat gctgttaaaa tatgttacac
    18961 tagcattagc tttaatttca atagaaagta tctgatatag gttatgaatt atcattttga
    19021 tgcctctaag ttaaagttgg gcatgcgtac gtttaaaact ggcttagctg tgttttttgt
    19081 tttgcttttg tttcattttt ttgattttca gggcctgcag ataggggcct tgacagctgt
    19141 ttttagcttg agagagagct ttgataagac gatctccttt ggcacctctc gtattttagg
    19201 aaattcgatt ggtggttttt ttgcgattat attttacctg cttgatactc tttttcaggg
    19261 cgcattttgg gttaccttgg tttttgttcc gatattgacg atgctaacca ttatgtttaa
    19321 tgtggctttt aataatcaat ctggcatcat cggtgcagtt gctgctcttt taattatcac
    19381 cttgtctatt cctactggcg aagcttttat gtatgttatt gctcgggttt ttgaaacctt
    19441 ttgtggggtt tttattgcca ttcttgtcaa tacagacgtg gagctgatta gaaataagtg
    19501 gttgagcagg aagctcaaaa aatgatgtca gaaaacataa catgtgacct tgacagttta
    19561 ttaaaatcaa cctataatag gggtgtgaaa ggaagttttc atgaaagaaa aagaactcag
    19621 acgctcaatg gcagtctttc cgatcggtgc agttatgacc ttgacagatc tatctgctcg
    19681 gcaaattcgc tattatgagg accaggagct gataaagcct gagagaacag agggcaaccg
    19741 tcgcttgttt tccttaaacg atatggatag acttcttgaa atcaaggact ttttggacga
    19801 aggattaaat attgcggcaa ttaagcgaga atatgctgaa cgccaggata aattaatgca
    19861 aaagcaaaag gtattgactg atgcagatgt gagacggatc ttacatgatg agcttcttaa
    19921 tcaaggtggc ttttccaccc cttcacagca tattgggaat tttcgtatct agcatacgac
    19981 tggcatgaaa gaaaaaggag attgattaat ggcaatcaca gcagctgatg ttcgtcgcga
    20041 ggtcaaagaa aagcatgtga cctttcttcg gttgatgttt acggacatta tgggtgttat
    20101 gaaaaacgtt gagatacctg caactgagga gcaattagat aaagtcctat ctaataaggt
    20161 catgtttgat ggctcctcga ttgaaggctt tgtgcgtatc aatgaatcag atatgtatct
    20221 ctatcctgat ttagacactt ggatcgtctt tccttgggga gatgaaaatg gaactgttgg
    20281 tggcttgatt tgtgatattt acactgctga aggcaagccc tttgctggtg acccacgtgg
    20341 caacctaaaa agagccttga agcatatgga tgaggttggc tatcagtcct ttaaccttgg
    20401 tccagagcca gaatttttct tgtttaagat agatgaagct ggagaaccaa cgcttgaggt
    20461 caatgacaag ggaggctatt ttgacctcgc tccgattgat ctggcagaca atacccgtcg
    20521 tgaaattgtt aatgtcttga ccaaaatggg ctttgaggtc gaagccagcc accatgaggt
    20581 agctgtcggt cagcatgaaa ttgactttaa atatgcagat gccttgaagg cctgtgataa
    20641 tattcagatc tttaagcttg tggtcaaaac cattgcgcgt gagcacgggc tctacgctac
    20701 ctttatggca aagccgaaat ttggtattgc cggctcaggt atgcattgta acatgtcctt
    20761 atttgataaa gggggcaaca atgcctttta tgatgaaaat gataagcgtg gcatgaagct
    20821 atcagatgat gcctattatt tcttaggtgg gttgatgaag catgcttaca attacaccgc
    20881 tatcacaaat ccaacggtta attcctacaa gcgcttggtt cctggttatg aggctcctgt
    20941 ttatgttgct tgggcaggaa gcaatcgttc acctcttatt cgtgttcctg cttctcgtgg
    21001 tatggggact cgtttagaat tgcgttcggt tgatccaaca gccaatcctt atttagcact
    21061 tgccgtttta ctagaggcag gcttagatgg tatcattaat aaaattgaag cgccggcacc
    21121 gattgaggct aatatttaca tgatgacagc agaggagcgc aatgctgctg gcattgttga
    21181 tttaccgtca acactccata atgctctaaa ggcgcttcaa aaggatgagg tcattcaaaa
    21241 ggctttaggt gatcatattt acaccaactt tttagaggca aaacggattg aatggtcttc
    21301 ctatgcgacc tttgtttcgc aatgggagat tgataattac ttacacaact attagaaaat
    21361 caaaactcac tcagcttttt gagtgagttt tttatgcttt tattcagcag atatggttat
    21421 ttatacttat cgttcctttt atacgctatg agg
//
LOCUS       DARYXW010000030        21157 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.030, whole genome shotgun sequence.
ACCESSION   DARYXW010000030 DARYXW010000000
VERSION     DARYXW010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21157
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.030"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            74..1252
                     /locus_tag="TV191_000896"
                     /pseudo
     CDS             74..1252
                     /locus_tag="TV191_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560651.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
     gene            1212..2660
                     /locus_tag="TV191_000897"
     CDS             1212..2660
                     /locus_tag="TV191_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEL1507426.1"
                     /translation="MLVVKKNQRQKSLNYWQKRQKDILSYLDRTDLDVFSELQKLYNE
                     QAFELQKELFDFYTKYSEENKMTYQDVVKKLRHEDLSDYVANANKYRKQAEKDPELLK
                     RLNEQYVSARATRMDALNLELVYRAGILKGVLDSAFENHLKKVASYAYKKAMGGRSGT
                     INGPVLEELVRTPFDGYNYSEQLWGNTDNLVKNLQKRLKQGFVRGEHPRAMARDLAKR
                     FNVANHRAETLIRTDGTMVINNATARRYLNAGLKYYRDLVRLDDRTTEICRTIAKENK
                     RKLLSELKPGINVAPYHFNCRTTIIPDEDELSIEVEPIDDKSTKYFKDVTSDWIDGNE
                     HKPQLSLLNEYVKNGTPYKVDGHSVVLDHSNYEYRVANWLSKKTGLQVDMVPRVNSPE
                     HIKTPDYLVDGAPFDLKEITGSGKNVIDGNLRKAKKQATNIIFDITKTPLSFEEIMGQ
                     LEHIYMIDRRGLDISIIKNKDEVLAVLEKEGG"
     gene            2688..2876
                     /locus_tag="TV191_000898"
     CDS             2688..2876
                     /locus_tag="TV191_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507427.1"
                     /translation="MGVRPSSFFISIIHHPIKTIKEENMFIWQMVLVALGVLVLILIV
                     GIAAIAVKSIIAELKKEG"
     gene            2881..3138
                     /locus_tag="TV191_000899"
     CDS             2881..3138
                     /locus_tag="TV191_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507428.1"
                     /translation="MNKRIKKKRKLETAVVMLVAENAMQAEAIKNQNKQIMELKSIVQ
                     RNALATNEELATVKAATLDNQSVIKAIGDTVDYIKKNYKRK"
     gene            3315..3884
                     /locus_tag="TV191_000900"
     CDS             3315..3884
                     /locus_tag="TV191_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEL1507429.1"
                     /translation="MAEENVTTETTEQVDTQKEAVEHPKHEYERTFTRADISKMMAAE
                     RTKWESEQSAAIEKARTEGERLAKLSKDERAKEEEQKRLDAIAEREKAVAEREMRIET
                     HSLLVEKGLPLDFIDIVLATTAEEVKANIDNLQTIFDKAVEKRVNDRLTQKPPRTGNG
                     SVGMTKADIMAIEDDDERMRLIAENRNLF"
     gene            3897..4784
                     /locus_tag="TV191_000901"
     CDS             3897..4784
                     /locus_tag="TV191_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HEL1507430.1"
                     /translation="MAEKNLNTMADLGDIKSIDFVNKFSKNINDLLKLLGVTRRETLT
                     NDLKIQTYKWEVTLDQTDPGEGETIPLSKVTRTKDKDYTVKWFKKRRATTAEAIARHG
                     AARAITEADKRIMRELQNGIKDAFFTFLKTKPTKVKGVGLQKALSASWAKLATFNEFE
                     GSPLVSFVSPLDVANYLGDTKVGADASNVFGMTLLKNFLGMQNVIVMPSVPEGKIYST
                     AVENLVFASLNVKGGDLGGLFADFTDETGLIAAARNRQLSNLTYESVFFGANVLFAEI
                     PEGVVEATIEAAAVPGIGG"
     gene            4796..5152
                     /locus_tag="TV191_000902"
     CDS             4796..5152
                     /locus_tag="TV191_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEL1507431.1"
                     /translation="MGDKQLIDDIKLFIGISKGDGAQDELITLAIYESKERVLAKLNE
                     YSETEITKIPDRLRFIVRDVAIKRFNRINSEGAVEDSEEGKTFKWDSYLKEYESTLRS
                     AAIGKVYSGKGVARFI"
     gene            5163..5441
                     /locus_tag="TV191_000903"
     CDS             5163..5441
                     /locus_tag="TV191_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507432.1"
                     /translation="MIYKDRVILVYVDEQDDFLDKRTVEKPSGKIPCMENTFTKSEQM
                     GLFGKYDLNAFKLHLQGHYDGFSKIIYKGKSRLIKGLAHHKNSTVIYV"
     gene            5438..5782
                     /locus_tag="TV191_000904"
     CDS             5438..5782
                     /locus_tag="TV191_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEL1507433.1"
                     /translation="MSLIYRMRGLDRFLRSVERKQKSVRIAVDKELSKSAARIERQAK
                     ILAPVDTGWLRAQIYSEQQRLLHYRVVSPALYSIYLELGTRKMEAQSFLDPALRKEWP
                     VLMANIKKMFKR"
     gene            5786..6145
                     /locus_tag="TV191_000905"
     CDS             5786..6145
                     /locus_tag="TV191_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507434.1"
                     /translation="MDYSLETLYLKKVKNRLGVLDIPIYFKLPKSDVLEPFIVVGTNI
                     SDLSKTAQTGAVIDDFSLNIDAFLPGDSRLDAEEIKSRMLRLLGRNNQIKAQILVDNS
                     IGREVYRVAINITETLF"
     gene            6157..6756
                     /locus_tag="TV191_000906"
     CDS             6157..6756
                     /locus_tag="TV191_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
                     /protein_id="HEL1507435.1"
                     /translation="MANTKKGTTIEITTGKPIVGKKIFYFIQSVDAPKKSQALLPAYR
                     TDGTTTMGGEYIDEQTQQGRVIEKATDEHSIDLTTYFVPTDPSVAVIEEAKKTGKSIK
                     IWEVIADESVKEQIQIPESSGPKKDVYPAKFGYAKIDEIERGTGISDLVEMSYTANIV
                     GALQDGKFPLTKEEIEMLENVYGYQNPGDTTGDYDNITK"
     gene            6810..7265
                     /locus_tag="TV191_000907"
     CDS             6810..7265
                     /locus_tag="TV191_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507436.1"
                     /translation="MEFTAAKRNIDIKFDFKTMFKINNKLGTINPETGERNADGVGAL
                     FFNILERNESAIVDLVRLSAGSGKKALTEDEILDAIAEAVDEEGTTEGLFAEIEKEMV
                     DSGFFRAKILKYIENMEKSARYLKAKDDTDATQIQIIEDMIGRMSNAVS"
     gene            7340..7573
                     /locus_tag="TV191_000908"
     CDS             7340..7573
                     /locus_tag="TV191_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507437.1"
                     /translation="MEGLEYKQVAERENLSELSLKLRYTLNAKKVDVGKLKYDKHRLT
                     IKRSYQKASRSQADSDSSIVERIQMLNNHFQNR"
     gene            7588..11745
                     /locus_tag="TV191_000909"
     CDS             7588..11745
                     /locus_tag="TV191_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEL1507438.1"
                     /translation="MPGTFDGSIFADVGANTKDYEQAMARIVSTTQNAFRKAQDTAVN
                     SSNKMVQIIGQIMAQLANNGESLGKRLGSAYATGLKLSIGEIQRIAASIGEKIPEPIK
                     NGFNKAFSIIQNSVQKLSSAIPHPIKSAFTSATSAVVSFSSKITSAVSAAFNSVSSKA
                     STVADKISSSFGGRITSAVTNLATKLSTGLSNGFSRMSSSAATSLNGISQKFANTSSA
                     GERLKSTVMSIVQAFSLMAVAQKAMHALTGAIGGAVSRVDTMNRFPKTMALFGYSAEQ
                     SKASIDKLSKGIEGLPTPLDSAVKSAQQLAITTGSLDKGTSLALAFNNAMIGYGATTE
                     GAEQALRQFNQSLGSGKIQAEEFNSVSEAAPGLMSKMAEAFGFGKNGVQDLKSALSDG
                     KITAQEFADKMIELNDAQGGFAEMAQSSAGGIRTAWKNVHTAVVKGVAGMISAFDEAA
                     KANGMKTIAETLLSLKPAITSVFDTINSLIPNAVAAFARLKQSINIDFSPLGASVKEV
                     FALINIVFGDFAHTGELSEQAFDNLKAKITSLAPKVIALWAVMNPASAISTIMPLLSL
                     FGKVGLALGSLGTSVGAFGGIISSGIASASGVVGAFAATLSGLPGVFATAAGRGLSVL
                     GTMTSAMSSLVSLALAAIGPAAILGLVVAGLGLINSQFGAQIEQLLNTAVTKGPGIIQ
                     GLVKGITSKIPVLIASGTQLIAKFANAIAVLLPVIIQAGVQLITSLVQGIGQNATNLI
                     SSAIKIIGSFVSSIASALPQLISVGMELLLNVVNGIVQNIPLIIQQAQQIIDSFGNSL
                     QANLPSIISNGIAILVNLVQGITQMLPTVLQIATQVITSFVSGIVQFLPQLLQGGIQI
                     IISLVQGIIQNLPQIAQSAVQIIQSLASGLTQALPQIIAAGIQLVAQLAVALIKGLPQ
                     IISAGIQLIMGLGKAMLGAIPNALSGVWEGIKSGFSSMWDQITGKSSTSTAKVSADAT
                     VMAMNVGMQTTAMANQANTDTTSMLNSISQNTELANINATSNATQMANNVNAQTGTMS
                     LQGLNDSMSLASGISTNMSVANINATTQAREMASGVNGATSSMNLDAINHTLSLASGV
                     GANMGAASTGATSQAQAMSSGVSNSLASMQSNSTKAASGLSNSVTSEMSSAATSATSS
                     VNRLSSAVESGFNKAKTSATTSMNGIANAVKTGFSSINSTAKQSMANLVSSVTSGMSR
                     ATAVSNNACQKILSIFRALAGQMSSAGAYAGQGFANGLASSAGTIYAIANSIAANVAA
                     TIRRALDIHSPSRVTKTLGAFTGEGFALGMAEWIGEINSLGKAYATAVTDQNWGVNST
                     VSTSAKVNNSGINTSLDNLSEEVRQSQLSEPIFEVHNEIVGDKIYTAVKEKESREQSK
                     DSYFVFD"
     gene            11757..12599
                     /locus_tag="TV191_000910"
     CDS             11757..12599
                     /locus_tag="TV191_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1507439.1"
                     /translation="MDLLIEKESQATRLSDFGIYNIAIEDSAPLLSVSHRAVKGRSGY
                     IYDGATFTTKTLKVKGRVTVSNVERLLDKQDELNALLVVDEPFYVTKMYPENSDLFNF
                     ELPGESTGDLQLIGSPHKPWKYRFKVILDDTIAYEFIGKTSQGLKYNLSFALRTAELP
                     FGETKPKDITLSGGSFAYAGTAKASQLEWPFIIELTPSGGQTNFYIEIDGRRFEFKQN
                     SQLQNSDKLLLTGIATTLNGNYVNAKTNYEYFIFNPNPNKRITYKTDFLGTIRILNFV
                     ELYK"
     gene            12609..14591
                     /locus_tag="TV191_000911"
     CDS             12609..14591
                     /locus_tag="TV191_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1507440.1"
                     /translation="MITFLDHRDIEYGVISVIRHTNAVNGERSVSGEIYTNSDVLNNI
                     DRGWRLRFEDEYYVVIYAKPVDVGQKTQVSFDAIHQFFWDFSKSSIYEGLGDGSHTID
                     TYLETVFKGSGYRYKLEVGVNAFRKQSFNYKSRLDLFNEIIKATGLEFSVSGKVVRLL
                     KNIGTDLSTVVRKNFNMNDLTIEKNIDSFITYQKGFGAWTDPEDHSKGRLEAEYESPL
                     AKEYGRLEGAPLTDERFTVADNLKEALKSNVENSYKISVKIDMEDLTRAGYRCERPVA
                     GDYIMAINETLGFQERIRIVSFTSYYDATGALVKHEVTCNDIGSVKKQSVGSLSINSR
                     INQIDADIASAIEVATQALVSADGKNTVYGGTEMPKDEPKGTLKKGDILFLKVGDTTR
                     MYFWNGAEWEEPEVVNDPERWREDLEKQISEAIEKAKKAQEEINQRTDKELEEFRAAL
                     KNLALPEEAIKKITEAIKVDDIPSIKQSFDDLKNRVSETSEESRLTAEILGNNGKTRY
                     NKNLLVGEPNRVKKIDEDFIEVEANDGGFKRGETYTISFSQTCEPLKKVAITLIQANN
                     KGVKLVLTPTKAKMEPETFTLIKDTEVINVYPLSYSVTLSGDWYKSKQVDLNASEVRN
                     MALGMSYRDVVDGNNADLILDWAENPDIIFDGNGGI"
     gene            14591..15709
                     /locus_tag="TV191_000912"
     CDS             14591..15709
                     /locus_tag="TV191_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_192934711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronoglucosaminidase"
                     /protein_id="HEL1507441.1"
                     /translation="MSKEVASARIQHRGMTKQEWESSSDILMEREIGIDMTTGYPKVG
                     DGKNKFKDLKDLRGPMGPQGPSGERGLTGPIGPRGPAGKPGTTDYNQLQNKPNLDAFA
                     QKKETNSKITKLESSKADKSAVYSKAESKIELDKKLSLTGGIVTGQLQFKPNKSGIKP
                     SSSVGGAINIDMSKSEGAGVVVYSNNDTSDGPLMSLRTGKETFNKSALFVDYKGTTNA
                     VNIVMRQPTTPNFSSALNITSDNENGSAMQLRGSEKALGTLKITHENPNVEAKYDENA
                     TALSIDIVKKQKGGKGTAAQGIYINSTSGTTGKLLRIRNLSDDKFYVKSDGGFYAKET
                     SQIDGNLKLKDPTANDHAATKAYVDKAISELKKLILKK"
     gene            15724..17610
                     /locus_tag="TV191_000913"
     CDS             15724..17610
                     /locus_tag="TV191_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HEL1507442.1"
                     /translation="MSRDPTLILDESNLVIGKDGRVHYTFTAEDDNPKVRLASKCLGT
                     AHFNQLMIERGDQATSYVAPVVVEGTGNPTGLFKDLKEISLELTDTANSQLWSKIKLT
                     NRGMLQEYYDGKIKTEIVNSARGVATRISEDTDKKLALINDTIDGIRREYRDADRKLS
                     ASYQAGIEGLKATMANDKIGLQAEIKASAQGLSQKYDDELRKLSAKITTTSSGTTEAY
                     ESKLAGLRAEFTRSNQGTRTELESQISGLRAVQQSTASQISQEIRDREGAVSRVQQSL
                     ESYQRRMQDAEENYSSLTHTVRGLQSDVGSPTGKIQSRLTQLAGQIEQRVTRDGVMSI
                     ISGAGDSIKLAIQKAGGINAKMSGNEIISAINLNSYGVTIAGKHIALDGNTTVNGTFT
                     TKIAEAIKIRADQIIAGTIDAARIRVINLNASSIVGLDANFIKAKIGYAITDLLEGKV
                     IKARNGAMLIDLNTAKMDFNSDATINFNSKNNALVRKDGTHTAFVHFSNATPKGYTGS
                     ALYASIGITSSGDGVNSASSGRFAGLRSFRYATGYNHTAAVDQTELYGDNVLIADDFS
                     INRGFKFRPDKMQKMLDMNDLYAAVVALGRCWGHLANVGWNTAHSNFTSAVTNELNNH
                     INKI"
     gene            17622..18059
                     /locus_tag="TV191_000914"
     CDS             17622..18059
                     /locus_tag="TV191_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEL1507443.1"
                     /translation="MDLTLKNKDLNTLYSVLDKIKVTNMRANRGRAKLLAKVVDKFKE
                     YAKDEGDLIDLYAQKDKDGKFVIDEHKNIKLADPAKLDEFNGLLNELADEEIVIKGGE
                     YSKRFIDFLNFLEECEDEFTSSEIILIDNILEQFEESKKGEKP"
     gene            18056..18667
                     /locus_tag="TV191_000915"
     CDS             18056..18667
                     /locus_tag="TV191_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HEL1507444.1"
                     /translation="MRNWKVTGKYPQFDSTGAVASTHIIITAEDGSVISQPIKQGLTS
                     TNDTEIIKATLEEFKKSEYVEIAMGEAVQKVDDLEKISQETAKTAKTAQTAAGLAKVS
                     AERTQRMINLQTIHVLTSGGKVEPDIYKGMLELIEPAKQGEYQAYDVFTVVDESHEDQ
                     AGEGNLVFVHVNEPFTYDKQTLKELEEEDKVTVIKYADLVKQD"
     gene            18679..18951
                     /locus_tag="TV191_000916"
     CDS             18679..18951
                     /locus_tag="TV191_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507445.1"
                     /translation="MATELIFGLGGFILAIVTTYNIFNAKSIKHATDITLLQSEVEHL
                     KIVTRQNARRLEEHDEQNKTLITMTEQIKNLNREVRELKDIMRGEA"
     gene            18948..19175
                     /locus_tag="TV191_000917"
     CDS             18948..19175
                     /locus_tag="TV191_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEL1507446.1"
                     /translation="MINLKLRLQNKVTLMAILGAIFLLAQQLGIKLPSNIADIANTAV
                     TLLVLLGVVTDPTTKGLSDSEQALTYHEPKQ"
     gene            19292..20626
                     /locus_tag="TV191_000918"
     CDS             19292..20626
                     /locus_tag="TV191_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysin"
                     /protein_id="HEL1507447.1"
                     /translation="MATYQEYKSRSNGNAYDIDGSLGAQCWDGYADYCKYLGLPYANC
                     TNTGYARDIWEQRHKNGILNYFDEVETMQAGDVAIFMVVAGVTPYSHVAIFDSDAGSG
                     YGWFLGQNQGGANGAYNLVKIPYSTTYPTAFRPKVFKNAVTVIGNIGLNKGDYFIDVS
                     AYQQADLTATCQQAGTTKTIIKVSESLAWLSDRHQQQANTSDPIGYYHFGRFGGDSNL
                     AQREADLFLSNLPTKKVSYLVIDYEDSASADKEANTNAVIAFMDKIANAGYKPVYYSY
                     KPFTLNNIDYQQIIAKYPNSIWIAGYPDYEVRTEPLWEFFPSMDGVRWWQFTSVGVAG
                     GLDKNIVLLADDSSKVDIPKIDKPQSQLTFNQKLDTNTKLDNSNVPYYEATLSTDYYV
                     ESKPNASSADKEFIKAGTRVRVYEKVNGWSRINASQSDQWVEDKYLSNATQV"
     gene            20900..>21157
                     /gene="spei"
                     /locus_tag="TV191_000919"
     CDS             20900..>21157
                     /gene="spei"
                     /locus_tag="TV191_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_047373492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeI"
                     /protein_id="HEL1507448.1"
                     /translation="MSSVGVINLRNLYSTYDPTEVKGKINEGPPFSGSLFYKNIPYGN
                     SSIELKVELNSVEKAKFFSGKRVDIFTLEYSPPCNSNIKKNS"
BASE COUNT         6976 a         3772 c         4713 g         5696 t
ORIGIN      
        1 ccccaaaagt tagacataaa atctaacaat tggggggcta tttttatgtc taacttttgg
       61 ggggcagttc actattgacc ttatgtcggt cagaaacaat gaggactacc acaacgtcaa
      121 aataaaaaca gatttatcaa tttatggaag agcctacgag ctgttaactg ttgagaaaat
      181 agatgacaaa aaaaccgaag taaaactcta ccagctcccg gccgagcaaa cttttgttat
      241 ctatgatgat acataccagc gaaattcgtt gatggccgtt catttctacg acatagatta
      301 cggctcaggt aaacgtaaac agattatcaa agcatatact tccgacacaa tttataccta
      361 cgaagactat aaccttgaaa caaaaggtat gcgattaaaa gattatgaag gacatttttt
      421 tagaggtgta ccagtcaacg aatacgctaa taacgaggag cgaacggggg cttatgagtc
      481 tgtacttgat aatattgacg cctatgattt atctcaatca gagcttgcta actttcaaca
      541 agattcagtc aatgcgttgc ttgtaatagc tggtaatgct tacacaggag ctgatgagaa
      601 tgactactta gatgatggcc gattaaatcc taatggtcgt ttagcgatct caattgggtt
      661 taaaaaagcc caagtgttaa ttttagacga taatcctaat ccaaatggcg ttaaaccgca
      721 agcgtacttt ctcaaaaaag agtatgatac cgccggtagc gaagcctaca aaaatagatt
      781 agttgcagac attttgaggt ttacttttac gccagataca caagatatga aattttcagg
      841 agttcaatct ggtgaatcaa tgaagtataa gcttatggct tctgacaact atcgcgagaa
      901 gcaagagagg ttgtttaaaa aaggattaat gcgacgctta cgcttagcag ctaatatctg
      961 ggccatcaaa gggaatgaag caactacata tagccttgta aatgatacga gtatagtttt
     1021 cacacctaat cttcctcaaa acgataatga aattgttaca gctgcacaaa atctttatgg
     1081 cattgttagc gatcagacta tctttgaaat cttaaatact gtcacaggag tagatgctga
     1141 agcagagctt gaacgcttga aagaagaagc tgataaaaag caatctttac cggagcctag
     1201 attggtaggt gatgctagtg gtcaagaaga accaacggca gaaaagcctt aattactggc
     1261 aaaagcgtca aaaagatatt ctaagttatt tagacagaac tgatttagat gtcttttcag
     1321 aactgcagaa gttatataat gaacaggctt ttgagttaca aaaggaattg tttgattttt
     1381 atactaagta ttctgaagag aacaaaatga cttatcagga tgtcgttaaa aaactacgtc
     1441 atgaagattt atcagattac gtagctaatg ctaacaagta tcgtaaacaa gctgagaaag
     1501 atcctgagct gctaaaacga cttaatgagc agtatgtatc agcaagagct acaaggatgg
     1561 atgcattaaa tcttgagctt gtttatcgtg cggggatact aaaaggtgta cttgattcag
     1621 catttgaaaa tcatttaaaa aaagttgcct catatgctta taaaaaagca atgggtggac
     1681 ggtcagggac aatcaatggt ccagttttag aagaactggt tagaaccccg tttgatggtt
     1741 ataactattc agaacagttg tggggcaata ctgacaatct tgttaagaat cttcaaaaga
     1801 gattaaaaca aggttttgtt cgtggcgagc atcctagagc gatggccaga gatttagcta
     1861 agcgatttaa tgttgctaat cacagggctg aaacactaat cagaactgat ggaactatgg
     1921 tgattaataa tgctaccgct aggcgctact tgaatgcagg acttaagtat tatcgtgatt
     1981 tagttagact tgatgacagg acaactgaga tatgccgtac aattgctaaa gaaaacaaaa
     2041 gaaagctatt atctgagcta aagcctggaa ttaatgtagc accctatcat ttcaactgca
     2101 gaacaactat tattcctgat gaagatgagc taagtattga agtagaacca attgatgata
     2161 aaagcactaa gtattttaag gatgtcacct cagattggat agatggaaat gagcataaac
     2221 cacaactgtc actactaaat gagtacgtaa aaaatggcac tccttacaaa gtagatggcc
     2281 atagtgtcgt tcttgatcat tcgaattatg aatatagagt tgctaattgg ttatccaaaa
     2341 agacaggatt gcaagttgac atggtgccaa gagttaattc ccctgaacat atcaagactc
     2401 ctgattattt agttgatgga gctccttttg atctaaaaga aatcacaggt tcgggtaaaa
     2461 acgtcattga tggcaatcta cgaaaagcaa aaaagcaggc aactaatatc atttttgata
     2521 taacaaaaac ccctttatca tttgaagaga taatggggca attagaacat atttatatga
     2581 tagatcgtag gggtcttgat atatcaatta tcaaaaataa agatgaggta ttagctgtat
     2641 tagaaaaaga aggaggatga cccaccgcct ccacagtaaa ctgcttcatg ggcgttagac
     2701 catcatcctt ctttatctca attatacatc accctattaa aactatcaag gaggaaaata
     2761 tgtttatttg gcaaatggta ttagtggcac taggtgtatt ggtactcata ttgattgttg
     2821 gcattgcagc aatagcggtt aagtcaatta ttgcagaatt gaaaaaagaa ggataaaaca
     2881 atgaataagc gcattaagaa aaaacgtaaa ttggaaacag cggttgtgat gcttgttgca
     2941 gagaatgcca tgcaagcaga agctattaaa aatcaaaaca aacaaatcat ggagctaaaa
     3001 tcaatcgttc aacgaaacgc tctggcaaca aacgaagagt tagcgactgt taaagctgct
     3061 actttagata accaatcagt tatcaaggca attggtgaca cggttgacta tattaagaaa
     3121 aactacaaac ggaagtaggg gaaataaagt ttaaccgtgt cgaatttgac ctctttacaa
     3181 atctaaacca aagtcgtagc aatacggctt tttattgtgt ccaaactttg ttgatgacac
     3241 taaaagctac actgtttcgt cgcaggacgt aaagctagac tatcggttgg tggcgtaacc
     3301 actaggagaa agttatggca gaagaaaatg taacaacaga gacaactgag caagtcgaca
     3361 ctcaaaaaga agctgttgaa catcctaagc atgaatatga gcgaactttt actcgcgcag
     3421 acatctcaaa aatgatggct gctgaacgca ctaaatggga atctgaacaa tccgcagcta
     3481 ttgaaaaagc tcgtacagaa ggtgaacgtt tggccaagtt gtcaaaagat gagcgcgcta
     3541 aagaggagga acaaaaacgt ctagatgcta tcgcagagcg tgaaaaagca gtagcagagc
     3601 gtgagatgcg cattgagacg cattccctgc ttgtggagaa aggattgcca ttggatttta
     3661 ttgatattgt tttagccact actgcagaag aggttaaggc caatattgat aatttacaaa
     3721 ctatttttga taaagctgtt gaaaaacgtg ttaacgatcg tttaactcag aaaccgccac
     3781 gaactggaaa tggctcggtc ggtatgacta aggctgacat catggcgata gaggatgacg
     3841 acgaacgtat gcgtttaatt gctgagaatc gtaacttatt ttaagagggg aatattatgg
     3901 ctgaaaaaaa cttaaacact atggcggact taggagatat taaatcaatt gattttgtta
     3961 acaagttttc caaaaatatt aatgatttac taaaattgct aggggttact cgtcgtgaaa
     4021 cattaactaa cgatctaaaa attcagacct ataagtggga agtgacttta gatcaaactg
     4081 atcctggaga aggggaaaca atccctctgt ctaaggttac tcgaactaaa gataaagact
     4141 atacagtgaa gtggttcaag aaacgtcgtg caactacagc tgaggcaatt gctcgccatg
     4201 gtgcagctcg tgctattact gaagcagata agcgcattat gcgtgagctt cagaatggaa
     4261 ttaaggatgc attctttaca ttcctcaaaa caaaaccaac aaaagttaaa ggcgttggcc
     4321 ttcaaaaagc gctgtctgca tcatgggcta agctagctac ttttaatgag tttgagggtt
     4381 ccccgcttgt ttcttttgtc tctcctttag acgtagctaa ctatcttgga gatactaaag
     4441 taggtgcgga tgcctctaat gtttttggaa tgacattgct taagaacttt ttgggtatgc
     4501 aaaatgtgat tgttatgcca tctgtgccag agggtaaaat ctactcaacg gctgtagaaa
     4561 atctagtttt tgcatcttta aatgttaaag ggggagactt gggcggcttg tttgctgatt
     4621 ttactgatga gacaggttta attgctgcag ctcgtaatcg tcagctttct aatcttacct
     4681 atgaatctgt tttctttggg gcgaatgtac tgtttgctga aattcctgaa ggggttgtag
     4741 aggcaacaat cgaagctgct gctgtacccg gcattggtgg ttaaaggcta tttatatggg
     4801 tgataaacaa cttattgacg atatcaaact ctttataggt atttccaagg gtgatggtgc
     4861 gcaagatgag ctcatcaccc ttgctatata tgaaagtaaa gagcgtgtgc tagctaaact
     4921 taatgaatac tcagaaactg aaatcaccaa aattcctgat agattgaggt ttattgtccg
     4981 tgatgttgct attaaacggt ttaataggat taattcagaa ggagccgttg aagatagcga
     5041 agaaggaaag acttttaagt gggacagtta ccttaaagag tatgaatcaa cactcagaag
     5101 cgctgctatt gggaaggtat attcaggcaa aggggtagca agatttattt aggagataca
     5161 caatgatcta taaagataga gtaatcttag tgtatgtcga tgaacaggac gattttctag
     5221 ataaaagaac tgttgaaaaa cctagcggga aaatcccctg tatggaaaat actttcacaa
     5281 aatctgaaca gatggggcta tttggtaaat atgatttgaa tgcttttaag ttgcacttgc
     5341 aaggccatta cgacggcttt agcaagatta tctacaaggg aaaatcgagg ttgataaagg
     5401 gactagcaca ccataaaaat agcacggtta tttatgtatg agtcttattt atcggatgag
     5461 aggcctagat aggtttttac gcagcgttga gcgcaagcag aagtcagtac gaatcgctgt
     5521 agataaagag cttagtaaat cagctgctag gattgagaga caggctaaaa tactagcccc
     5581 ggttgacact ggatggctga gagctcaaat ctacagtgag caacaacgac tcttacacta
     5641 tagagtggtt tctcctgctt tatattctat ttatcttgaa ttaggtactc gtaaaatgga
     5701 agcacaatcg tttttagacc ctgccctgag aaaagaatgg cctgtgctaa tggctaatat
     5761 caaaaaaatg tttaagaggt gatgcatgga ttactcactg gaaacactat atttaaaaaa
     5821 ggtaaaaaat agattgggag ttttagacat accaatctat tttaaattgc ctaaatcaga
     5881 cgttttagag ccttttattg ttgtaggtac aaatatatca gacttgtcaa aaacagctca
     5941 aactggagca gttattgatg attttagcct gaatatcgat gctttcttac ctggcgatag
     6001 tcgtttggat gcagaagaga taaaatctcg catgcttaga ctgcttgggc gaaataacca
     6061 aataaaggct cagattttgg tagataattc aataggacga gaagtctata gagttgctat
     6121 caacattaca gaaacactat tttaaagggg acctaaatgg caaacacaaa aaaaggaaca
     6181 actattgaaa ttacaacagg taaaccgatt gtaggaaaaa agatttttta ctttatacaa
     6241 tcagttgatg caccaaagaa aagtcaggct ctgttgccag cctatcgtac cgatggtact
     6301 acaaccatgg gtggtgaata cattgatgag caaacccaac aaggtcgcgt tattgagaag
     6361 gctacagatg aacactctat tgatttgaca acgtactttg taccgacaga tccatctgtt
     6421 gctgtcatcg aggaagctaa gaaaacgggt aaatctatca aaatttggga agttattgcc
     6481 gacgaaagcg tcaaagaaca aatccaaatt cctgaatcga gtggtcccaa gaaagatgtt
     6541 taccctgcta agtttgggta cgccaagatt gacgaaatcg aacgtggtac tggtatttca
     6601 gacttagtag aaatgtccta caccgctaac attgtagggg ccttacaaga tggtaaattc
     6661 cctctcacga aagaagaaat tgaaatgcta gaaaatgtat acggctatca aaatccgggt
     6721 gatactactg gcgactacga taatatcact aagtagtaca caggggcggc gactgctgcc
     6781 ccattttgat ttaaaaagga gataaaataa tggaatttac agcagcgaaa cgaaatatcg
     6841 atattaaatt tgattttaaa actatgttta agatcaataa taaactagga acaattaacc
     6901 cagaaacagg agagcgcaat gcagatggtg ttggtgcttt gtttttcaat atcttagagc
     6961 gtaatgaaag cgccattgtt gaccttgtgc gtttatctgc gggaagcgga aaaaaagcgc
     7021 taactgaaga tgaaattcta gatgcaattg cagaagctgt tgatgaagaa ggaacaacag
     7081 aagggttgtt tgctgaaata gagaaagaaa tggttgattc tggttttttc agagcgaaga
     7141 ttttgaaata tatcgaaaac atggagaaat cagctcgcta tctcaaagcg aaggacgata
     7201 cggacgcaac tcaaatccaa attatcgaag acatgattgg aagaatgagc aacgcagtat
     7261 cttagtaaat tgcgcacggt tagggctcac agacattgat actatctata aatgtactaa
     7321 gtgggagcta gaggctatta tggaggggct tgagtataag caggttgctg agcgcgagaa
     7381 cctctctgaa ttgtctctaa aacttagata tacattaaat gctaaaaagg ttgatgtagg
     7441 taagctcaaa tatgataagc ataggctaac tatcaaaaga tcgtatcaaa aagctagccg
     7501 tagccaagcc gatagtgata gcagtattgt tgagagaata caaatgctta ataatcattt
     7561 tcaaaataga tagataagga ggagtagatg ccaggaacat ttgatggttc tattttcgct
     7621 gatgttggtg ccaacacaaa ggactatgag caggccatgg ctcgtattgt tagtacgact
     7681 cagaatgctt tcagaaaagc ccaagataca gcggttaaca gtagtaataa aatggttcaa
     7741 atcattggac aaatcatggc ccaattagcg aacaacggcg aatcgctcgg aaagagactt
     7801 ggttccgcct acgctactgg tttaaaactg agcattggtg aaattcaacg tatagcagct
     7861 tccattggcg aaaaaattcc cgaacccata aagaatggtt tcaataaagc tttttcaatt
     7921 atccaaaata gcgtacagaa gttatctagc gccatccctc accccataaa atccgcattc
     7981 acaagtgcaa caagtgcagt agttagcttt tcgtctaaga tcacaagtgc cgtctcagca
     8041 gctttcaact ctgttagttc taaagcgagt actgttgcag ataaaatcag tagtagtttt
     8101 gggggtagaa tcacttcagc ggttactaat ttagcgacta agttaagtac aggtcttagc
     8161 aatggtttta gcagaatgtc tagttctgcg gctacttcct tgaatggaat cagccagaaa
     8221 ttcgccaaca cctcttctgc tggagagaga ctcaaaagta cagtgatgag catcgtgcag
     8281 gcctttagtt taatggctgt tgctcaaaaa gctatgcacg ctcttactgg ggcaataggc
     8341 ggggcggtta gtcgggttga taccatgaac cgctttccga aaacgatggc actatttggg
     8401 tattctgctg aacaatctaa ggcatcaatt gataagttgt caaaaggaat tgaaggtctg
     8461 ccaactcccc tagatagcgc tgtgaaaagt gctcagcagc tcgccataac cacaggaagt
     8521 ttagataaag gaactagttt agccctcgcc ttcaataatg caatgatcgg ttacggtgca
     8581 acaactgaag gggctgagca agcactcagg cagtttaacc agtcgttggg gtctggaaaa
     8641 attcaagctg aagagtttaa ctctgtatca gaagctgcgc cgggtttaat gtctaaaatg
     8701 gcggaagcct tcggttttgg taaaaatggc gtacaagatt taaaatcagc cttatctgat
     8761 ggcaaaatca ctgcacaaga gttcgcagat aaaatgattg agcttaacga tgcccaaggc
     8821 ggatttgcag agatggccca atcatcggct ggtggaatcc gaactgcgtg gaagaacgta
     8881 cataccgccg ttgtaaaagg cgtagcaggt atgatttcag cctttgatga agcggctaaa
     8941 gctaatggta tgaagaccat tgctgaaaca cttcttagtc tgaagccagc aataaccagt
     9001 gtttttgata cgattaattc tcttattcca aatgcagttg cagcattcgc taggctaaaa
     9061 cagtctatca atattgactt tagcccatta ggcgccagcg ttaaagaggt gtttgctctt
     9121 attaatattg tttttggaga ttttgcacat actggtgaat tatcagagca ggcttttgat
     9181 aatctaaaag caaaaatcac ttctttagct cctaaagtca ttgccctttg ggcagtgatg
     9241 aaccccgcta gcgctatatc aacgataatg cctttgcttt ctctattcgg aaaagttggt
     9301 ctagctttag gaagcttagg gacttctgtc ggggcgtttg gcggcataat ttctagtggg
     9361 atagctagtg ccagcggcgt tgttggtgcc tttgcggcaa ctctaagcgg attacctggc
     9421 gtttttgcta ccgcagcagg gcgtgggcta tctgtgcttg gaactatgac aagcgcaatg
     9481 tccagtcttg tgagtttagc actggcggcc ataggaccgg ccgctattct aggtcttgtg
     9541 gtggcaggac ttggtttgat taatagtcag tttggcgcac aaatcgagca gctacttaac
     9601 accgcagtta caaaaggtcc tggcattatt caaggccttg taaaaggaat tacttctaaa
     9661 ataccagttt tgatagctag tggcactcaa ttgattgcta aatttgcaaa tgctatcgca
     9721 gtgttattac cagttataat tcaagctggc gttcagctaa ttacgagtct cgtccaaggt
     9781 attggacaaa atgcaacgaa tttaattagt tcagcaataa aaatcattgg tagttttgtt
     9841 agttcaattg cgagtgcatt gccgcagctt atttctgttg gaatggagct attattaaat
     9901 gttgtcaacg gcatagttca aaatatacct cttattatcc agcaagccca gcaaattatt
     9961 gatagttttg ggaatagttt acaggctaac cttcctagta ttattagcaa cggtatagct
    10021 attttggtga atcttgtaca gggaattact caaatgttgc caactgttct gcagatagct
    10081 actcaagtca ttacgagttt tgtatctgga attgtacagt ttttaccgca gttacttcaa
    10141 ggtggcattc aaatcattat tagccttgtg caggggatta ttcaaaatct accccagatt
    10201 gcacaatctg ctgtacagat tatacagtct ttagcttctg gactgacgca agctctacct
    10261 cagattatcg cagcaggcat tcagcttgtt gcgcaactag ccgtagcctt gataaagggg
    10321 cttccacaga ttatttctgc gggtattcaa ttaattatgg ggctcggtaa agccatgtta
    10381 ggggctatcc caaacgctct ttcaggagtt tgggaaggta ttaagagcgg attcagttcg
    10441 atgtgggacc aaatcacagg taagagttcc acaagtacag ctaaagtctc tgcggacgcc
    10501 acggtcatgg ccatgaatgt tgggatgcaa acgacagcta tggctaatca agctaataca
    10561 gatacgacat ctatgcttaa tagcattagt caaaatacag agcttgctaa tataaacgct
    10621 acatcaaatg ccacacagat ggctaataac gttaatgctc agacaggaac gatgagtctt
    10681 caggggttga atgattcgat gtctcttgcg agtggcatta gcactaatat gtctgtcgct
    10741 aatataaacg ctactactca ggctcgagaa atggcttcag gggttaatgg tgcgacttct
    10801 tcaatgaatc tagacgccat taatcatacg ctcagcttag ctagtggtgt tggtgcgaac
    10861 atgggagctg ctagcacagg tgcaacttct caggcgcaag ctatgagctc aggggtgagt
    10921 aacagcctgg catcaatgca gtcaaactca actaaagcag cctctggtct gtctaatagt
    10981 gtgacaagcg aaatgtcttc tgcagcaacc tctgcaacct caagcgttaa taggttgtcc
    11041 tcggcggtcg agtctggctt caataaggcg aagacttcag caacaacctc aatgaatggg
    11101 atagccaatg cggttaaaac aggatttagt agcattaaca gtactgcaaa gcaatctatg
    11161 gcaaaccttg taagttcagt gacttctggg atgtctcgtg caaccgcggt gtctaataat
    11221 gcttgtcaga agatcctctc aatattcagg gctttggcag ggcagatgtc ttctgcagga
    11281 gcttatgcag gtcaaggttt tgctaatggt ctagctagta gcgcaggcac aatctacgca
    11341 atagctaaca gcattgccgc taatgtagca gcaacaatta gacgcgcttt agatattcac
    11401 tcaccatctc gtgtcactaa aacactaggt gcatttactg gagaggggtt tgccctcggt
    11461 atggcagagt ggataggtga gatcaatagc ctaggtaaag catacgcaac agcagttact
    11521 gatcaaaact ggggggtaaa tagtactgtt tcaacatctg ctaaagttaa taatagtgga
    11581 atcaatacct ctcttgataa tcttagcgaa gaggttaggc agtctcaatt gtcagagcct
    11641 atctttgaag tgcataatga gattgttgga gataaaattt acacggctgt taaagaaaaa
    11701 gaatcaagag agcaatctaa agattcttat tttgtttttg actagaaggg agtattttgg
    11761 atttattaat agaaaaagag agtcaggcaa ctaggttgtc tgactttggt atttataata
    11821 ttgctattga agatagcgct cctttactat ctgtatcaca ccgagcagtc aaaggaagga
    11881 gtggttacat ctacgatggg gctactttta cgactaaaac gcttaaggtc aaaggaagag
    11941 tgacggtaag caacgtggaa agacttttgg acaaacagga cgaactaaac gctctgcttg
    12001 ttgttgacga acctttctac gtgactaaga tgtaccctga aaactcagat ctatttaact
    12061 ttgagcttcc aggggaaagc acaggagacc tgcaacttat tggctctcct cataaacctt
    12121 ggaaatatag atttaaagtc atcttagacg acactatcgc ttatgaattt ataggaaaaa
    12181 ccagtcaagg actaaaatat aatctttcct tcgcgctaag aactgctgaa ttacctttcg
    12241 gtgagacaaa gccaaaggac ataactctat cagggggcag ttttgcctat gcaggaaccg
    12301 ctaaagcaag tcagctagag tggcctttta ttatagagct tactccttct ggaggtcaga
    12361 ctaattttta tattgaaatt gatggcaggc gctttgagtt taagcagaat agccagctac
    12421 aaaatagtga taaattactt ttgacaggca tagctaccac actaaacgga aattatgtca
    12481 atgctaaaac gaactatgag tattttatct tcaatcctaa tcctaacaag agaattactt
    12541 acaaaacgga ttttcttggc acgattagga ttttaaattt tgtagagttg tataaatagg
    12601 gaggtctaat gattactttt ttggatcatc gtgacattga gtatggggtc attagtgtca
    12661 ttaggcatac taatgctgtt aatggtgagc gctcagtgag cggggaaatt tatacaaaca
    12721 gtgatgtcct caataatatc gatagagggt ggcgacttag atttgaagat gagtattacg
    12781 ttgttattta cgcaaagcct gttgatgttg gtcaaaaaac gcaagtttcg tttgatgcca
    12841 tacaccaatt tttttgggac ttcagcaaga gtagtatcta tgagggtctc ggagatgggt
    12901 ctcataccat tgatacctat ctagagacag tatttaaagg tagtgggtac cgctataagc
    12961 tagaagtagg tgtgaacgca tttagaaaac aatcttttaa ttataagtcc aggttagatt
    13021 tattcaatga gattattaaa gcgaccggac ttgaattttc agtcagcggg aaagttgttc
    13081 ggctattaaa aaacataggt actgatctgt caacagtggt acgaaaaaat ttcaacatga
    13141 atgaccttac cattgaaaag aatattgata gctttattac ctatcagaaa ggctttggtg
    13201 catggaccga cccagaggac cactctaagg ggagacttga ggcggaatac gaaagtcctc
    13261 ttgccaagga gtacggtcga cttgaagggg cgcctctgac ggatgagcgc ttcacggtgg
    13321 cagataatct aaaagaagct ttaaaaagta atgttgaaaa ttcatataag atatcagtaa
    13381 aaattgatat ggaagattta acgagagctg ggtatagatg tgagaggccg gttgctggtg
    13441 actacattat ggcgataaat gagactttag gttttcaaga gcgtatacgg atagtttctt
    13501 ttacaagcta ctacgacgca actggagctt tagtaaaaca tgaagtcact tgtaatgata
    13561 tcggatctgt gaaaaaacaa agcgtaggaa gtctgtctat aaacagtaga atcaatcaga
    13621 tagatgcaga tattgcttct gcaattgaag tagcaacaca agcactagta tctgctgacg
    13681 ggaaaaatac tgtttacggt ggcacagaaa tgcccaaaga tgaaccaaaa ggaaccttaa
    13741 aaaaaggaga catattattc ctaaaagttg gcgatactac tagaatgtat ttctggaatg
    13801 gtgctgagtg ggaagaacct gaggttgtga acgacccaga acgatggcgt gaagacctcg
    13861 aaaaacaaat ctctgaggcg atcgaaaaag ccaaaaaagc acaggaagaa atcaaccaac
    13921 gcaccgataa agagcttgaa gaatttagag ccgccctcaa aaacctagcg ttaccagagg
    13981 aagcgattaa aaaaatcaca gaggctataa aagttgatga catcccgtct attaaacaaa
    14041 gctttgatga cctcaaaaat agagtgagtg agacaagcga agaatctcgt ttaactgccg
    14101 aaattttagg gaacaacggt aagacacgct acaacaaaaa tttgctggtc ggtgagccta
    14161 atcgtgttaa aaaaattgat gaggatttta tcgaggtaga agctaatgat ggtggtttca
    14221 agcgtggcga gacttacaca atcagcttta gtcagacatg tgagccgctc aaaaaagtgg
    14281 ctatcacgct gatccaagct aataataagg gagttaaact ggtactgaca cctactaagg
    14341 caaaaatgga gcctgagact tttactctaa ttaaggacac agaggtcatc aacgtctatc
    14401 ctttgagcta ctcagtcact ttaagtggtg actggtacaa atctaagcaa gtagatttaa
    14461 atgcgtcgga ggtgcgaaat atggctctgg ggatgagtta tagagatgtg gttgatggta
    14521 ataatgctga tttaattttg gactgggcgg aaaacccaga tattattttt gacggaaacg
    14581 gaggtattta atgtcaaaag aagttgcatc agcaaggata cagcatagag gcatgaccaa
    14641 acaagagtgg gaatcaagct ccgatatctt aatggagcga gaaattggaa ttgatatgac
    14701 tacgggttac ccaaaagttg gtgatggcaa aaataagttc aaggacttaa aagacttgcg
    14761 cggccctatg ggacctcaag gtccttcagg agaaagaggc ctaactggcc caattggtcc
    14821 tcggggccct gctggcaagc ctggaacgac agattataat caactccaaa ataaaccaaa
    14881 tctagatgcg tttgcacaaa aaaaagaaac taatagtaaa atcaccaaat tagaatcaag
    14941 caaagcagat aaaagcgctg tttactcaaa agcagagtca aaaatagagc tagacaaaaa
    15001 attgagtttg acaggcggca tagtgacagg acaactacag tttaaaccta ataaaagtgg
    15061 tattaaaccc tcatcttccg taggaggagc gattaacatt gatatgtcta aatcggaagg
    15121 tgctggtgtt gttgtctatt ctaacaatga taccagtgat gggccgttaa tgagcttgcg
    15181 gacgggtaaa gagaccttca ataaatcagc gctttttgtc gattataagg gaacaacaaa
    15241 tgccgttaat attgtgatgc gtcagccaac cacccccaat ttttcatcgg cgcttaatat
    15301 tactagcgac aatgaaaatg gtagtgcaat gcagctacga gggtcagaaa aagcgctagg
    15361 aacgctcaaa atcacacacg aaaacccaaa cgttgaggca aaatacgatg aaaacgctac
    15421 agcgttatct attgatatcg ttaaaaaaca gaaaggcgga aaaggtactg ctgctcaagg
    15481 aatctacatt aactcaacat caggcacgac agggaagttg cttaggatta gaaaccttag
    15541 tgatgataag ttctacgtca agtctgacgg tggtttttat gccaaggaaa cttcgcagat
    15601 tgatggcaac ctgaaactca aggaccccac agcgaatgat catgcggcaa ccaaagctta
    15661 tgtagataaa gcaatttctg agttaaaaaa actcatacta aaaaaataga ttaaggagga
    15721 taaatgagca gagacccaac acttatttta gacgagtcaa acctcgttat tggtaaggat
    15781 ggacgtgtgc attacacatt taccgcagag gacgacaacc caaaagtcag actagctagc
    15841 aagtgtctag gcacagcgca ttttaatcag ctcatgattg agcgaggaga ccaagctact
    15901 agctatgttg cgccagtagt agttgagggt acaggtaatc cgactggact atttaaagac
    15961 ctcaaagaga ttagcctaga gctgacagat actgctaatt cccagctttg gtcaaaaatc
    16021 aagctgacta accgtggtat gttgcaggaa tactacgacg gtaagatcaa gaccgagata
    16081 gtcaactccg ccagaggtgt cgctacacgt atcagcgagg atactgataa aaagctagcg
    16141 ctcatcaatg acaccattga tggtatcagg cgtgagtatc gagatgctga taggaagcta
    16201 tccgcaagct atcaggcagg catcgagggg ctaaaagcca caatggccaa tgataaaatc
    16261 ggtttacaag ctgagattaa agcctcagca caagggctat cgcaaaagta tgatgatgag
    16321 ttgcgcaagc tatcggctaa gatcacaaca acctcaagcg gcactacaga ggcctacgag
    16381 agtaagcttg cgggcttacg tgctgagttt actcgctcaa atcaaggcac gaggacagag
    16441 ctcgagtcac aaattagcgg gctaagagcg gtacagcagt caacagctag ccaaatctct
    16501 caagagatta gagaccgtga aggtgctgtc agtcgtgtgc agcagagttt ggagagttac
    16561 caaaggcgga tgcaggacgc agaagaaaac tatagtagct tgacccatac ggttagaggg
    16621 ctacagagcg acgttggatc tccgactggt aaaatccaat cgcgccttac tcaactagca
    16681 ggacaaattg agcagcgggt tactagagat ggtgtcatga gtattattag tggcgctgga
    16741 gacagcatta aattagctat ccaaaaggct ggcggcatta atgccaaaat gtctggtaat
    16801 gagattatct cagcaattaa cctcaactcc tacggagtaa caatcgcagg taaacacatc
    16861 gctctcgatg gcaatacgac tgtcaacggc acctttacca caaagatagc agaggctatc
    16921 aagattaggg ctgatcagat tattgcaggc acgattgacg ctgctaggat tagagtgatt
    16981 aaccttaacg caagtagtat cgttggttta gacgctaact ttatcaaagc taaaattggc
    17041 tatgctatca ctgatttgct cgagggtaag gtcattaagg ctcgtaatgg agcgatgctt
    17101 atcgacttaa atacagctaa gatggacttt aatagcgatg ccacaattaa ttttaatagc
    17161 aaaaacaatg ccttagtacg taaagatggc acacatactg cctttgtaca ttttagtaat
    17221 gcgacgccca aaggttatac agggtcagcg ttgtatgcat cgatcgggat aacctcatct
    17281 ggtgacggtg ttaactcggc ttcttccggt cgttttgcag ggctaaggtc atttaggtac
    17341 gctacgggat ataatcatac tgctgcagtc gaccaaaccg agctatacgg tgataatgtc
    17401 ttgattgcag atgactttag catcaatcga ggatttaaat ttagaccaga caagatgcaa
    17461 aaaatgcttg acatgaacga cttgtatgcg gctgtagtag ccttaggccg ctgttggggg
    17521 cacttggcta acgtcggctg gaatactgct catagcaatt ttacaagtgc ggtcactaac
    17581 gagttaaata atcatatcaa caaaatttaa taggagaaac aatggattta acgcttaaaa
    17641 acaaagattt aaacacacta tatagtgtac tagacaaaat caaagtcacg aacatgcgag
    17701 caaaccgcgg acgtgctaag ctactcgcaa aagtagtcga taaattcaaa gagtacgcca
    17761 aggatgaggg tgaccttatt gatctgtatg ctcaaaaaga caaagatggc aagtttgtca
    17821 ttgatgagca caaaaacatc aagctagcag accccgctaa actcgacgag ttcaacggcc
    17881 tactcaacga gctagctgat gaagaaattg tgattaaagg gggtgagtac tccaagcgat
    17941 ttattgactt tttaaacttt ttagaagagt gtgaagatga atttacatca tctgaaatca
    18001 ttcttatcga caacattttg gaacaatttg aagaaagtaa aaaaggagaa aaaccatgag
    18061 aaattggaaa gtgacaggaa aatacccaca atttgacagc acaggagcag tcgcaagcac
    18121 acatattatt atcactgctg aggatggctc agtcatctct caaccaatca agcagggctt
    18181 aacttcaact aatgacacag agattatcaa agctactttg gaagaattta aaaaatctga
    18241 atacgtcgaa atcgctatgg gcgaagccgt gcaaaaagta gacgaccttg aaaaaatctc
    18301 acaggaaacc gctaagaccg ctaaaacagc ccaaacagcc gcaggattag ctaaggtgtc
    18361 cgcagagcgt acacagcgga tgattaactt gcaaaccatc cacgtattga caagtggtgg
    18421 gaaagttgaa cccgatatct acaaaggtat gttagagctt attgaacctg ctaaacaagg
    18481 cgagtatcag gcttatgacg tgtttactgt tgtagatgag tcgcacgaag atcaagcggg
    18541 agaaggtaat cttgtctttg tacacgttaa cgagccgttt acttatgaca aacagacgct
    18601 taaagagcta gaggaagagg ataaagtcac agtcattaag tatgcggact tagttaagca
    18661 ggattagcga ggtaagctat ggcaacagag ttgatatttg gtcttggtgg ctttatttta
    18721 gctatcgtca cgacttacaa tatttttaat gcaaaatcca tcaagcatgc gacagatatt
    18781 actttgttgc agtctgaagt agagcattta aaaattgtta cacgccaaaa tgctcggcgt
    18841 cttgaggagc atgatgagca aaacaaaacg ctcatcacaa tgacagagca aattaaaaac
    18901 ctcaatcgtg aggtaagaga acttaaagat attatgagag gtgaagcatg atcaatttaa
    18961 aattacgact acaaaacaaa gtaaccttga tggctatttt aggagctatc tttttactgg
    19021 cacagcaatt aggtattaaa ctaccatcaa acatcgcgga tattgcaaac acagctgtaa
    19081 cgcttttggt attgctcggt gttgtcacag atccaaccac gaaaggcctg tcagacagtg
    19141 agcaagcttt gacttaccac gaaccaaaac aataggaggg gacatgcggg caatcacacg
    19201 attagcatta gttatagcaa tagcaatact gtatgtgcca ttatctgttg ttgctttgat
    19261 tttaagccca tttttagata aggagggata aatggctaca tatcaggaat ataaaagtcg
    19321 ttcaaatggc aatgcttacg atattgatgg atcgcttggt gcgcaatgtt gggatggcta
    19381 cgcagactac tgtaagtatc taggactgcc atacgcaaac tgtacaaata caggatatgc
    19441 aagggatata tgggaacaac gtcacaaaaa tggtatttta aactactttg acgaagtaga
    19501 gactatgcaa gctggagatg tcgcaatttt tatggtagtt gcaggtgtta caccgtatag
    19561 ccatgtggct atttttgata gtgatgcagg tagtggatac ggatggtttt taggtcaaaa
    19621 ccagggtgga gcaaacggag catataattt agtaaaaata ccatattcaa cgacttatcc
    19681 tactgcattt agaccaaaag tttttaaaaa tgcagttact gttataggta atataggact
    19741 aaataaaggc gattatttta ttgatgtatc agcttatcaa caagcagact taaccgctac
    19801 ttgtcagcaa gctggcacta ctaaaacgat tatcaaagta tccgagtcac tcgcttggct
    19861 gtctgatagg catcagcaac aagctaatac tagtgaccct attggttatt atcactttgg
    19921 acgatttgga ggagatagca acttagcgca acgagaagca gatttatttc tgtccaattt
    19981 accaaccaaa aaagtctctt acttagtcat tgattatgaa gactctgcaa gtgccgacaa
    20041 agaagctaac actaatgcag ttattgcgtt tatggataaa attgcaaacg ctggatataa
    20101 gcctgtttat tacagctata aaccatttac gcttaataat attgattatc agcaaattat
    20161 cgctaagtac ccaaacagca tttggatagc tggttatcca gactacgaag tacgaacaga
    20221 gccactttgg gagttcttcc cttcaatgga tggtgtgcgc tggtggcagt tcacaagtgt
    20281 aggagtagca ggtggtttag ataaaaatat tgtattatta gcagatgata gtagcaaagt
    20341 ggatatacct aagattgaca aaccacaaag ccagcttact tttaatcaaa agctagatac
    20401 taacactaaa ttagacaact cgaatgtacc ttactacgaa gcaaccctta gcacagacta
    20461 ttatgtagag tctaagccaa acgcaagtag cgctgataaa gaatttatca aggcaggaac
    20521 tcgtgtaaga gtctatgaaa aagtgaatgg atggtcacgt attaacgctt ctcagtctga
    20581 ccagtgggtc gaagataagt atttatctaa tgcaacacaa gtataaaata ggaggtaaag
    20641 ctcctttaga taagacaaat gccctcgctt ttgcgggggc tgtttttgtt ataaagattt
    20701 taattgttat ttaagcattt tcgttgattt ttttcttttt tgtgctaaaa tattttgtga
    20761 tttcttatta ttaaagaaga atagggtaca cttataagtg agaaaaattg taaatgttaa
    20821 ttttaaaaag tttttaactt catcttttct attgtgggta tttatatcag ctataattcc
    20881 aacgtgttac gcgtatgaga tgagtagtgt gggagttatt aatttaagga atttatactc
    20941 tacatatgat ccaacagaag taaaaggaaa aataaatgaa ggtccgccat tttcaggtag
    21001 tttgttctac aaaaatattc cttatggcaa tagttcgatt gaattaaaag tagaacttaa
    21061 tagcgtagaa aaagctaaat ttttttctgg taaaagggtg gatatattta ctttggagta
    21121 ttctcctccc tgtaactcta atataaaaaa gaattca
//
LOCUS       DARYXW010000031        20895 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.031, whole genome shotgun sequence.
ACCESSION   DARYXW010000031 DARYXW010000000
VERSION     DARYXW010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20895)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20895)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20895
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.031"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            126..1541
                     /locus_tag="TV191_000920"
     CDS             126..1541
                     /locus_tag="TV191_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1507449.1"
                     /translation="MRKNKLLRMIMLMTLLVPHLETARVLAEDTGAEASQVPATANEA
                     AIAQTGESTSTAAATSATDNSSSTTETTPNSGEPGATGSSSNTASSGSASGSTGQSTP
                     TSPAASPQPAPEVATQASQPALNIVPAAPTVDLSLTLALPSVNTYAAYVTHWSGQSAY
                     THNLLSRRYGIKAEQLDSFLKSTKIKYDEKRINGAALLQWEKKSGLDVRAIVAIAMTE
                     SELGTKGNATLLGSNMFGYALFDLDSKKPNQFNDELAIVKLTQETIIKNSNLNFEQQD
                     QKADKFAKKQLNFASDGGLYFTDTNGIGKRRAEIMEKLDAWIDQHGGTPEIPAELKIQ
                     SSSSFAVVPTGYKLSKSYDILSYQASSYAWGQCTWYVYNRAKELGYQFDSFMGNGGDW
                     RFKSGYSISKEPKVGYAVSFAPGQAGADGLYGHVSIVEDVRKDGSILISESNCLGLGQ
                     ISYRTFTAEQANQLTYVVGKS"
     gene            1743..5494
                     /locus_tag="TV191_000921"
                     /pseudo
     CDS             1743..5494
                     /locus_tag="TV191_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922617.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NEAT domain-containing protein"
     gene            5723..6628
                     /locus_tag="TV191_000922"
     CDS             5723..6628
                     /locus_tag="TV191_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein"
                     /protein_id="HEL1507450.1"
                     /translation="MKIINEEHMIKRLFKKLMGGLVVLLVCLAAIGGKAYADKGELYS
                     CVIRRDYRHPVSGQIEDSGGEHAFEIGQGMVEGTVYSNGMLEVTSAGDLYLTFRMSLA
                     DFSGNYQFWVQPGGTGAFQAAAYSVTKVGTDTNGTTKDIAIALPDVNTVVRGSMYVEP
                     MGREVVFYLSPSELQEGYSGDMVASFAAGEAKTDHAVTAPAKADEKKAPSKPDSKDAK
                     SAPNPSARPVGQSSSPKKQSNPSKKGQAVGLSTSLDKSKQESSQKPVNNPLPVLVYYV
                     PTALLLSGALVLFIKKKRKNNEESH"
     gene            6612..7496
                     /gene="isdE"
                     /locus_tag="TV191_000923"
     CDS             6612..7496
                     /gene="isdE"
                     /locus_tag="TV191_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter substrate-binding protein
                     IsdE"
                     /protein_id="HEL1507451.1"
                     /translation="MKKVIKLIGLAVLSLVLSACVDQHPRAEKKADKERIVATSVAVV
                     DICDRLSLDLVGVCDSKLYQLPKRYDAVKRIGLPMNPDMEVIASLKPTWILSPNSLQN
                     DLEPKYQQLDTEYGFLNLTSLEGMYQSIDDLGDLFDRKKEAKRLRADYEEFYRAFKKK
                     HKGQKKPRVLILMGLPGSYLIATNKSYVGNLLELAGGENVYHSEDKEFLSANPEDMLQ
                     QQPELILRTAHAIPDKVKDMFDKEFAENDIWKHFEAVKSQQVYDLDNTLFGMSAKFNY
                     KEALNHLSQIFYGAKEVK"
     gene            7498..8520
                     /locus_tag="TV191_000924"
     CDS             7498..8520
                     /locus_tag="TV191_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEL1507452.1"
                     /translation="MQQGSQYSDQVTAARKRTTRLVYMVLLLMLLFGLMLYAVSVGGL
                     SVSYQRIFNGLFVAYDSEVALIYDLRFPRIVIALLAGAGIATSGVLFQAILKNPISDP
                     AIIGVCSGASFMVLLSSLLLPQLLFYGPLLSFVGGCVSFLMIYTLSWKKGLQPIRIIL
                     TGIAINALFLGLSRAITDFSKTSNPFVNALLSGNISQKTWADVGVLWPYTVLGLLLAI
                     GLARQCDLLLLNDGLIRNLGIDSNYLRLGISLVAVLLAAVSTSIVGVVSFLGLIVPHI
                     GRLLVGSKHSYLIPFSALLGAFVFLLADTLGRQLCYPLEISPAVIMSIVGGPYFIYLL
                     RRSDVI"
     gene            8517..9299
                     /locus_tag="TV191_000925"
     CDS             8517..9299
                     /locus_tag="TV191_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1507453.1"
                     /translation="MSHEQGLIRVEDLSFTYRDRPILDRLSFTIPKGKITTIMGANGC
                     GKSTLLGLLTKNIPVKSGQIFLEGQAISSISLKQFAQKVAVVHQDNQAVADLLVGDLV
                     AVASQAHRRFFKGSSQEDDDIVAWALEVTNLRELAFREMQELSGGEKQRVWIAMALAQ
                     KTGVLVLDEPTTYLDIKYQLDILALIKKINQELGMTIIMVLHDINQALAVSDCVLGLQ
                     KGAIYAQGSPQEVLDQAFVEAVFGVSLPFIEKQDRRFVLTTL"
     gene            9345..11108
                     /locus_tag="TV191_000926"
     CDS             9345..11108
                     /locus_tag="TV191_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HEL1507454.1"
                     /translation="MNDTTEKISRAKKKMLLRRLKERIAPKRFLLYVSAFLSWLQFLM
                     RLMSFYLIAKQFTAFLAGQALQLTRLLVILLILNAVGFGLAMIAKQLQGLASQFARDS
                     LKQSFFDAFIAMDGQFDQQSTEADVLTVASQGIDSLDTYYSYYLSLAMLTAFNCTTVL
                     LLVFLIYPIGGLVFILSLPLIPISIVAMQKRSKRIMNHYWSTYMDVGNLFMDDLKGLN
                     TLYSYQADERYEESFVNKAEAFRKATMQLLGFQLQAVGYMDAVMYLGIGLSGFLAVQA
                     LSAGGISFFDFLFFILIATEFFAPIREQGYGMHLVMMNTKMADQIFGFLDSVEAVDQD
                     KGVALPAFDRIDIQDLSFSHGEKALLRDITMTIKKGELTAVAGVSGQGKTSLAQLLLK
                     RYQADSGQIFLGDVTIDLASKQAINQEILYVSDQSTLLNMSIYENLAMAAQLTRKELL
                     SWIDEHGILSFIYWLPDGIDTIVGENGCHLSAGQRQQVICARALLSQRSCYIFDEATS
                     SLDAENEAAIHRLLQQLAKQAIVIVITHKMKYLKQADQVLFLSPEQSASLASPRELYR
                     HHLAYRQLVDTQVELEANLYG"
     gene            11101..12783
                     /locus_tag="TV191_000927"
     CDS             11101..12783
                     /locus_tag="TV191_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1507455.1"
                     /translation="MVKSDYSTYRLVLRLLAMMKHLLAWIALAVMFAVLGFVLTVGIP
                     TSLAYLGLEVMAGHAITFKWLYLFVAMALLRGLVRYGEHYFGHFVAFHSLAAFRRIVF
                     KKLRALSPARLDSQDSGHLLKMIGEDIEALEVFFAHTLAPICTAFISASLMAYYLWQV
                     SWKLALGAIVTYVLLAVIIPVYFSNVLQSLLKKQNEGRRAYVSSFLESLRSVKDLLQF
                     QSIEKRFKLLSNQSKHVNALDRQVAQAQFLQMAITFLALGLSILTFAYVTLFELSQQT
                     VTFAGGLLAFVAFTASFAPFLELGRLPLGFKRAMNAARNVFQLLDEEALVDKGDQRIS
                     SVTRIAVEDLTFAYPKHQETIYHHLSVAFEKKGIIGIQGESGSGKSTLMKIIMKWYNW
                     QAGHIFLSEVDSQTLNAASLQANFAYVPQNAQLFQQTLRDNITLGRKDISDDDIMELA
                     EACGMKERILACDEGLDTLVRGSADFSAGEAQRLELMRALLKRADCYIFDEPTSNLDS
                     LNEAIFIDLIKKHCRGMVFLISHRPSTLACADQLFCVRNGFLKEVNNERVNH"
     gene            12764..13357
                     /locus_tag="TV191_000928"
     CDS             12764..13357
                     /locus_tag="TV191_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEL1507456.1"
                     /translation="MKGLTIKDIMTTGAFAALYFVCVGLGAMLSILFDRSGNMLYAPA
                     FAALLGGPVYMLLIAKLQTFGPISLVGIIMGSFFFLTGHFFASMLPAILFGCLADGIA
                     LLGKYQSRLVNLLSYLVFAFVNSGPIILMWLLKDAYIQSLLARGKDMAYVNRIMYDFT
                     VANVSWFVGVVLLCALVGGLFGQYLLKKHFAKSGMLL"
     gene            13354..14034
                     /locus_tag="TV191_000929"
     CDS             13354..14034
                     /locus_tag="TV191_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEL1507457.1"
                     /translation="MRLDVRTKLLLLILANACFFFRIDGWLGTMIIGVLLGILFWLGQ
                     GRLAIGMTLLYALLLALSVLPLHVLPAYLFRLLSFAAVAGQLLYPSVLAALIFVKTTT
                     AYELVHGLRKWHVPEVCLLTLAVMLRFLPKIRQEGKIIRQSLKIRGIFLDSWAIVRQP
                     RRYMEYLLVPLLMSLLRSSQDLTIASLTKGLAIKKGASECFVSHLSWKDWGVQIWIFV
                     TIAYMVLQ"
     gene            13971..15425
                     /locus_tag="TV191_000930"
     CDS             13971..15425
                     /locus_tag="TV191_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1507458.1"
                     /translation="MEGLGGTDLDICDDSLHGSPVIKAKQLQFSYTNRRQTACELRDC
                     QIEAGQFIVLCGQSGSGKSTFLKLLNGLIPDYFSGQLQGSLKVLSHQAGQASVEVLSR
                     QVSSVFQNPASQFFYREVKHELVFPCENQGLEPALILERLDTLAADFDIKDLLEADML
                     KLSGGQKQRVAIAAAIMQGTAIMVFDEPTANLDHASVAAVKAYLKQLKAAGKTIIVAE
                     HRLHYLLDLADHFYYFSAGRLERVLSPKDLLALPDQEREELGLRRCELTAVTKALRAK
                     TVFEHYDPEHALQIKQLEVKAGSRVLYHLNQLSFGAGQITGITGANGLGKSQLALYLA
                     GIFEAKEAKISYLGVTLPAKDRLSITSLVLQDVGLQLFSETVEKELNLGHHRHQATDD
                     LVNRLGLSQLLDKHPASLSGGEQQRVMIAASLLSDKEIVILDEPSSGLDLLQMQALVS
                     LLKELKQQKKVVIVISHDEELLDQACDSIYQLSR"
     gene            15789..17804
                     /gene="recG"
                     /locus_tag="TV191_000931"
     CDS             15789..17804
                     /gene="recG"
                     /locus_tag="TV191_000931"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEL1507459.1"
                     /translation="MLLKSSIANLKGLGPKSAEKFQKLGIYQIKDLLLYYPFRYEDFK
                     SKSALELLDGEKAVLTGRVVTPPSVQYYGFKRNRLSFKLKQGELVISVSFFNQPYLLE
                     KIVLDQEVAIFGRWDQKKAALTGMKLLMTLEDDLQPVYHVAQGISQPTLIKAIRSAFD
                     SGALAQLEENLPEPLIQKYRLLPRQAAVYAMHFPKHMEDYKQALRRIKFEEFFYFQMN
                     LQVLKLANKAEGNGLAIPFHQQAVAKKIAALPFSLTRAQQRSLEEILADMTSGAHMNR
                     LLQGDVGSGKTVIASLAMYAAQTAGFQSALMVPTEILAEQHYDSLCQLFPDLSIALLT
                     SGMKAAEKRAALSAIADGSVDMIVGTHALIQDAVTYHKLGLVITDEQHRFGVNQRRLF
                     REKGNNPDVLMMTATPIPRTLAITAYGEMDVSIIDELPAGRKPIITRWVKHRQLDSVL
                     AWVKTELAKGTQAYVISPLIEESETLDLKNAVALEAELKDYFKASASVALMHGKMKAD
                     DKEMIMQRFKAKEIDVLVSTTVIEVGVNVPNATIMLIMNADRFGLSQLHQLRGRVGRG
                     SKQSYAILVADPKTDSGKERMTIMTTTNDGFVLAEADLKLRGSGEIFGTRQSGLPEFK
                     TADIVEDYHILEEARRVAAEIVAAKDWQLDPRWAPILANLRVADQFD"
     gene            complement(17924..18889)
                     /locus_tag="TV191_000932"
     CDS             complement(17924..18889)
                     /locus_tag="TV191_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEL1507460.1"
                     /translation="MKEILVLHTGGTISMQADEAGKVSPNQNNPMNQVGLSLEHIHLT
                     VVDFLNLPSPHITPHHMLKMYHYIQQRASQFDAVVITHGTDTLEETAYFLDTMVLPVE
                     LPIVITGAMRSANEIGSDGIYNYLTALRVASHEKAKGKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGVVMKDDLLFFKTAEPRVRFELRHISGTVPIIKAYAGMGDGSI
                     LSLLTPDRIQGLVIEALGAGNVPPLAVSELEKLIASGIPVVLVSRCFNGIAEPVYAYR
                     GGGASLKRAGVMFVKELNAPKARLKLLIALNAGLTGQELKDYIEG"
     gene            18961..20349
                     /locus_tag="TV191_000933"
     CDS             18961..20349
                     /locus_tag="TV191_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL1507461.1"
                     /translation="MTIKAVFFDIDGTLLNDRKNVQKTTQRAIQQLKKQGIMVGLATG
                     RGPAFVQPFLENFGLDFAVTYNGQYILTRDKVLYQNQLPKSTIYKIIRYASDKKREIS
                     LGTASGLAGSRIIDMGTSPFGQMVSSIVPRSLVKTVEGSFKNLIRRFKPQSFSNLVTI
                     MREPIYQIVLVASVDDTQKIKERFPHIKVTRSSPYSLDLISSGQSKIKGIERLGEMFG
                     FELSEVMAFGDSDNDLEMLSGVGVGVAMGNAEAVVKSGAHFTTASNNNDGISKALAHY
                     GLIHFDVEKSFKSRDDNFNKVKDFHRLMDGDTIETPRGYSLKEAGYRADFKVEELVEF
                     LYAASQGDKHRFSQALIDLHAALDKAAKKVQAKEHPESPLVGQVDALTDLLYFTYGSF
                     VLMGVDPQPIFETVHEANMGKIFPDGKAHFDPITHKIQKPDDWQERYAPESAIKKELD
                     KQLQKSLQRLEK"
     gene            complement(20635..>20895)
                     /locus_tag="TV191_000934"
     CDS             complement(20635..>20895)
                     /locus_tag="TV191_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEL1507462.1"
                     /translation="AKEVLGDFEKQAREAGLTEVKQVIEFGNPKTLLAHDIPDKEEVD
                     LIMVGATGLNTFERLLIGSSSEYILRHAKVDLLVVREHDKTL"
BASE COUNT         5598 a         4151 c         5093 g         6053 t
ORIGIN      
        1 aataagaaaa ggcccttacc tttatccgag tattaaggca ttaatacaaa aaatcttgca
       61 ttttattttg cttcaatgtt ataatgtagg ttagaataga gcagaaagaa gtgattgaat
      121 actaaatgag aaaaaataaa ttattaagaa tgataatgct gatgactctt ctggtacctc
      181 atttagagac cgcaagagta ttggcagagg atacaggagc tgaagccagc caggttccag
      241 ctactgctaa tgaggctgca atcgcccaga ctggtgagtc cacttcgaca gcagctgcta
      301 cctcagctac tgacaactcc tcatcaacca ctgagactac tcccaacagt ggagaacctg
      361 gagcaacggg gtcatcaagc aatacagcta gctctggatc agcttctggt tctactggac
      421 agtcgacacc tactagtcca gcagctagcc ctcagccagc ccctgaagtt gctacacagg
      481 catctcagcc ggcactgaat attgttcctg ctgctcctac agttgatttg tccttgactc
      541 tggccctgcc ttctgtaaat acctatgctg cttatgtgac gcattggagt ggtcagagtg
      601 cttataccca taacctcttg tctaggcgct atgggatcaa ggcagagcag cttgatagct
      661 ttttaaagtc taccaagatc aagtatgatg agaagcgaat taacggtgct gccttgctgc
      721 aatgggaaaa aaagagtggg ctagatgtgc gggcgattgt agccattgca atgacagaaa
      781 gtgagctagg aaccaaggga aatgcaacct tactaggctc taacatgttt ggctatgcgc
      841 tttttgacct tgattcgaaa aagccaaatc agtttaatga tgagcttgct attgttaagc
      901 tgacacagga gacgattatc aaaaatagca accttaattt tgagcagcag gatcaaaagg
      961 ctgataaatt tgccaaaaag cagttgaact ttgctagtga tggtggtctt tacttcacag
     1021 ataccaatgg cattggcaag cgtcgcgctg agatcatgga aaaattagat gcttggattg
     1081 atcagcatgg aggcacgcca gagattccgg ctgagctgaa aattcaatcc tcttcaagct
     1141 ttgctgttgt tcctacaggc tacaagctgt ctaagagcta tgatatttta agctatcagg
     1201 cgtcaagcta tgcttgggga caatgtacct ggtatgttta taatcgcgct aaggagctag
     1261 gctatcagtt tgattccttt atgggaaatg gtggtgactg gagatttaag tctggctaca
     1321 gtatttctaa ggagccaaag gtaggctatg cggtttcctt tgctccaggt caagcgggtg
     1381 ctgacggtct ttatgggcac gtctctattg ttgaggatgt cagaaaggac ggctccatcc
     1441 tgatttcaga gtcaaattgt cttggcttag gtcagatttc ataccgcacc tttactgctg
     1501 agcaggccaa ccaattgact tatgttgttg gaaaatcata agtaatcttc ttgctttaaa
     1561 ggcgagaagt acagaatttt tgtaagaaaa aatccagctc tgttgcaggg ctgttttttt
     1621 ctttgcttta ttgtgaaaaa aatctcaaat tcaatcttga caaaggcttg acaacataat
     1681 aaattaagtg agattaataa aataattaaa tggctaataa catttttaga aggttcgaaa
     1741 taatgaaaag tatcaataag tgcgccattc ttgctttatc aacgctggct cttgcccagt
     1801 ctgcccagac ggttcgctca gaggctactc aagtctcttc aagtcttgtg acgactgtca
     1861 agcttaagga taatatttta ttgttcgagg agatcggtcc ctatgcggac aagtcagagg
     1921 ggaagctcta ttataaaaat atcgagaaaa ttctcattga tggtaaagag tatgacaaaa
     1981 agctggaggg tgactatagc tatgacatca attaccaagg aatcaaggta aacgctaaga
     2041 acatcacaga aggacagcat cagctgcgca tcgtcaataa gactaacgga ggcattcttg
     2101 tggtctttga caagaaagga aatgatgtta cctttgtttc tgccaagcct tcagatgata
     2161 ctactgcttc accgcagcaa gctgctgcta agacagaaaa gcctgctaag gtaactagcc
     2221 atgatggctt agcgacccta tcatttatca ccaaactaga gacaacagaa ggagagcttc
     2281 tttttccgga aattgatcgc tattccagca ccaagcaaat taaggaatta gctcatcaaa
     2341 tcacaaagat caaggtcaat gaccaggact ataaggattt ggtctatgat tcagtaaagg
     2401 acaagcctgg ctatgtgtct gacctgaagg ggcttcatct tgggacgaca gctttcaagg
     2461 agggagaaaa caaggttgtc atttcctcac aaagctttga agatgtcatc attacagtga
     2521 aaaagtcagg ggagcaatac acctttgttt ctgctaagca aaagcagaga caaggatccc
     2581 agcaggaagc accgcaggga cttgatttta ctaagctgga aagcgcgatc aaggaagctg
     2641 agcgtatcat tgctagcgag gccaataaag aacaggtcaa ggacttgtct agcaagcttc
     2701 aggtgatcaa ggagtcctat cgtcagattg acaatgaaaa attgctcaag gagacctatg
     2761 agcttttgat ggatagtatc aagtcctatc agggaactga tctggctgtt acggatctaa
     2821 aggcaggaac ctatacctta acctttaagg ccaataagga aaatacagag gaagcctcaa
     2881 tgctgcaggg agcatttgat aagaaggcca agctggtcgt caaagaagat ggcaagatgg
     2941 agatttcatt gctcaataca gctctagggc aatttttgat tgacttttcc attgagagta
     3001 aagggcagta tccaacctct gtccgcactc aggttggtga acgcgatatt aacaataact
     3061 acattagagt gaatttaccc taccgattga ggagctggac aagcttcaca agggtgctgt
     3121 gctagtatca gctatgggtg gtcaggaaag cgacctacat cactatgaca aatacaccaa
     3181 gttggacatg acctttagcg ctacagcaag taagggctgg acaggctatc aggctgagat
     3241 tgacgacaag gaaaaagggg tcggctctga gcgtcttgaa aaggttttgg ttaagcttgg
     3301 taaggacctt aacggtgatg gcaaaatgtc acctgaggaa attgcgaaga ttgaaggtga
     3361 gctgcgccta gaccactatg atttgacaga tatttcactc ttaaagcatg ctaagcatat
     3421 tactgagctg cacttagagg gcaatcagat tgcaagcatt ccaaaggaaa ccttcagtca
     3481 aatgaccaat ctaaggttct taaatcttcg cagcaatgtg attacaaccc tagataagga
     3541 tacctttgct cataacagcc agctaaaaga gctctatctc tcaagcaact atatgccaaa
     3601 tctggaggaa ggactattta gaaatcttgg tcagctggat cagctagatc tgtcaaaaaa
     3661 tagaatcagc gtgattcgag atggtgtctt taatggtcta tctcgcttga cctccttggc
     3721 cttggctgaa aatatcatta ctgaattttc agaaaatgct ctagcttcac ttgataatct
     3781 aaacttcttt gatgtttctg aaaaccagtt gggcagcctg ccaagctcct tgagtaagct
     3841 aactaagctt tcttatatcg ttgccaatcg aaaccaggtt ttagatattg ctaatattga
     3901 ctttagtcat atgccaaact tattaaccgt tgacttggca tcaaatgagc taactaaaat
     3961 cccacaggga gccttcaagg ctaataagca gctatcaaag cttaatgtct ataataacct
     4021 tttaacgaat attagcgaag ctgattttgc agatctaaag gcattggatc ttgatcttaa
     4081 gtttaactgc ctaagtggcg ttagtgataa gcttagacag atcatgggaa caaataagct
     4141 aaacccacaa aagcaatttg ctaatctatc tgcgacttta aatcatcaag cgatgaccta
     4201 tcaccaaggg tttagcctgc ttgatttgta ttattgggag cagcagacac tctcaagcac
     4261 cgaagcagaa attagctctg ttgaggatta caataaacgc cttaaggcaa gctcgtcaga
     4321 catcattgcc ttattaaatg agcgttatgc tgactgggat attgtggtgc aattgcagaa
     4381 aaaaacatca accggtcaat atgtcaccgt tgatgagaga cgcttgaata acgatccaca
     4441 agatgagctt caaggctcct ttgacctaaa gggagcaggt gtttatcgtg ttcgtaaggc
     4501 tcttatcacc aaggaatttg ctaagaagcg tgagcatatt tatctgacct ctaatgatgt
     4561 tgaggtcaag gaggatcagc ttgcaggtag tgaccagtct aagggcttgg atattaataa
     4621 gcttgaagat ggtgtctact acatcaaggc aagcatgctt aaaaatgatt tgcagtcaga
     4681 atcaatgtct catcaggcta ttgaccaccg cgtcaaattg attgtgaata agggtgtcta
     4741 tagcctagag gtgaccttta agggcatgaa gatcggtaac ctgacagggt atctcggaga
     4801 gttgagctac tttgttgatg gctaccaaag ggatttgact ggcagaccgg ttggtaagac
     4861 agaaaaagca gaggttgtgt cctactttac agatgtcaca ggcaagcccc tgtcagacgc
     4921 ttatggcagc aattacccac aggtgttgag atttaggctg attgatcagg ctaaaaagga
     4981 tggcttggta cctcttcgcg tctttgtgcc aattatggac gctatctcta agggaacagg
     5041 cttccagaca gtctttatga agttggatct tcaaagcctg acaaaggata aggcacaatt
     5101 gccacactca gaggacaatc agggacatgg taccataggt gagctcttgc agcctcacac
     5161 aggtatcatt ggtggtcata caagtcctgc tattcctaat ttgaccaatc ttttgactaa
     5221 gaagtcagct gctccaagca gtaatgccaa ggaggacgct aagaccggta cagataagct
     5281 taagagcctg atttcttcac ataaggcgtc taaggctggt acaggcaagg cctctaagca
     5341 ggctgctaag actagagcca aagctaaatc taaggctgct aaacatagtc aggagcagat
     5401 gaaagctgat catcgcggcc atatcattat cggtctagca agctttattg tcatagcagt
     5461 tggtctcatt cttggtagga aaaaattatt ttaagtcagt agagagtctg tttgatgcac
     5521 taagagcttg gtttaatcgc ttgtagtcat caaggcttat caacgatacg taaaggcatg
     5581 cctgtttcta atgatttctt aagcttaccc ttggtaagtg aggaatgggt atgcttttcg
     5641 tatttgaggt gttataatag tcaaataaga gtaggtcttg gcctgcgtct aaatctatgc
     5701 cttatttgat tgtcgtaagg aaatgaagat cattaatgag gaacatatga taaagagatt
     5761 attcaaaaaa ttaatgggtg gcttggtggt attgctggtt tgcctagcag ctataggagg
     5821 taaggcctat gctgataagg gtgagcttta ttcctgtgtg attaggcgag attatcgtca
     5881 cccggtttca gggcaaattg aagatagcgg tggtgagcac gcttttgaga ttggccaagg
     5941 tatggtggaa ggaacagttt atagcaatgg tatgctagag gtaacctcgg ctggggattt
     6001 gtatctgacc tttcgcatga gtctagctga tttttcaggt aactaccaat tttgggttca
     6061 gccgggtggt acaggggctt ttcaggcggc agcctacagt gtcaccaagg ttggcactga
     6121 taccaatggc acaacaaagg atattgcgat tgctttgcct gatgtcaata cggttgttag
     6181 aggcagcatg tacgtagagc ctatgggcag agaggttgtc ttttacctgt caccatctga
     6241 gctacaagaa ggctacagtg gagatatggt agctagcttt gcagcaggag aagccaagac
     6301 ggatcatgcg gtgacagctc ctgcaaaggc agatgagaag aaagctccta gtaaaccgga
     6361 ctcaaaagac gccaagtcag ctcctaatcc ctcagcaagg ccagttggtc aatcaagcag
     6421 tcccaaaaaa cagtcaaatc cctctaagaa gggtcaggca gttggtttga gcacttcgct
     6481 agataaaagt aagcaagagt cgtcccaaaa gccagtaaat aatccattgc cagttctggt
     6541 ttactatgta ccaacagctc ttttgttgtc aggagccttg gtcttgttta taaagaaaaa
     6601 gagaaaaaac aatgaagaaa gtcattaagc ttattggatt agctgttttg tccttggtgc
     6661 tatctgcttg tgtggatcag caccctaggg cagagaaaaa ggctgataag gagagaattg
     6721 ttgccacctc tgtggctgtt gttgatattt gtgatcggct aagcctagat ttggttgggg
     6781 tctgtgacag taagctatac caattgccaa agcgttacga tgctgtcaaa aggatcggtc
     6841 tgccgatgaa tcctgatatg gaggttattg cttctctaaa gccaacgtgg atactcagtc
     6901 ccaattctct gcaaaatgat ttagagccta aataccagca attggatacg gaatatggct
     6961 ttttgaattt aactagcctt gaaggcatgt accagtcgat tgatgatttg ggggacttgt
     7021 ttgatcgcaa aaaggaagct aagcgcttgc gggctgatta tgaggagttt taccgggcct
     7081 ttaagaaaaa gcataaaggg caaaaaaagc ctagggttct tattttgatg gggcttcctg
     7141 gcagctatct gattgctaca aataaatcct atgttggtaa tctgcttgag ctggctggtg
     7201 gtgagaatgt ttatcactct gaggacaagg aatttttgtc tgccaatcca gaagacatgc
     7261 ttcagcagca gcctgagctg attttgcgta ctgcccacgc cattccagac aaggttaagg
     7321 acatgtttga taaggaattt gctgaaaatg atatttggaa gcattttgaa gctgtcaagt
     7381 ctcagcaggt ttatgattta gacaataccc tttttggcat gagtgctaag tttaactaca
     7441 aagaggcttt gaaccatctg tcacaaatct tttatggagc aaaggaagtc aagtaagatg
     7501 cagcaaggta gtcaatattc tgatcaagtc acagcagcaa gaaaaaggac cactagactg
     7561 gtctatatgg ttctattgct catgctgctg tttggtttaa tgctatatgc ggtctctgtt
     7621 gggggcttat ctgtttctta tcagaggatc tttaatggct tatttgtagc atatgattca
     7681 gaggtagccc ttatttacga tttacgcttt ccaaggattg tgattgcttt attggctggg
     7741 gcggggatag caacatctgg ggtcttgttt caggcgattt taaaaaatcc tatttcagat
     7801 ccggcgatta ttggggtttg cagtggggct agctttatgg tcttgttatc tagcctgctt
     7861 ttgccgcagc tcttgtttta tggtcctttg ttatcatttg tgggaggctg tgtttctttt
     7921 ttgatgattt ataccttgtc ctggaagaag ggcttgcagc cgatacgcat cattttgaca
     7981 ggaatagcta tcaacgcctt gtttttaggc ttgtctcgtg cgattactga tttttcaaaa
     8041 accagcaatc cctttgtcaa tgcgctgttg tcaggaaata ttagtcaaaa aacctgggca
     8101 gatgttggtg tgctgtggcc ttatacagtg cttggcctgc tgcttgcgat aggcctagca
     8161 aggcagtgtg atctactgct gctaaacgat ggcttgattc gtaatttagg cattgatagt
     8221 aattacctgc gcttaggaat ctcgttggtt gcggtcttac tagctgctgt ttccacctcg
     8281 attgtgggtg tggtgtcatt tttaggcctg attgtgccgc atattggccg ccttttagtt
     8341 ggcagtaagc atagctatct cattcctttt tctgccctgc ttggcgcctt tgtctttttg
     8401 ctggcagata ccttaggaag gcagttgtgt tatcccttgg agattagccc agctgttatc
     8461 atgagcattg tcgggggacc ttattttatt tatctgttaa ggaggtctga cgtgatatga
     8521 gtcatgagca aggcttgatt cgtgtagagg atttgtcctt tacttatcgt gataggccta
     8581 ttttagatag gctgagcttt accattccaa aaggcaagat aacgacaatc atgggggcaa
     8641 acggctgtgg caaatcaacc ctactaggtc tgctgactaa aaatatcccc gttaagtctg
     8701 ggcaaatttt cttagaggga caagctatta gctctattag tcttaagcag tttgcccaaa
     8761 aagtagccgt tgtgcatcag gataatcagg cggtagcaga tcttctggtg ggtgatttgg
     8821 tggctgtggc aagccaagcc catcggcgtt tttttaaggg atcaagtcaa gaggacgatg
     8881 acattgttgc ttgggcctta gaggtgacta atctaaggga attggccttt agggaaatgc
     8941 aggagctatc tggtggtgaa aagcaaaggg tctggattgc tatggcgctt gcccaaaaaa
     9001 caggtgtctt agtgcttgat gagccaacca cttatcttga tattaagtac cagctggaca
     9061 ttttagccct catcaaaaaa atcaatcagg agctaggaat gaccattatc atggtgttac
     9121 atgatattaa tcaggccttg gctgtttcgg attgtgtgct tgggctgcaa aaaggtgcca
     9181 tctatgccca aggcagtcca caggaggttc ttgatcaggc ttttgtggag gcggtttttg
     9241 gggtgagctt gccctttatt gaaaagcagg ataggcgatt tgttcttacc actttatgag
     9301 acaaataaaa aatgaatgat agataggaat aaggcgacga ttatatgaac gatacaactg
     9361 aaaaaatatc acgcgcaaag aaaaaaatgc ttttaaggcg tttaaaggag cgtattgctc
     9421 ctaagcgttt tttgctttat gtgtcggcct ttttatcttg gctgcaattt ttgatgcgtt
     9481 taatgagctt ttacttaatt gctaagcaat tcacagcctt tttagcaggt caagccctgc
     9541 aattgacaag gctgcttgtt atccttttga ttttaaatgc tgttggcttt ggcttggcga
     9601 tgattgcaaa gcagctgcag ggcctagctt cgcaatttgc gcgtgactcg ctcaagcaat
     9661 ccttttttga tgcctttatt gctatggacg ggcaatttga tcagcagtca acagaggctg
     9721 atgtgttaac ggttgcctca caagggattg atagcttgga tacctattat tcctattacc
     9781 tatcgcttgc aatgctaaca gcttttaatt gcacaacggt cttactgctt gtttttttga
     9841 tctatcctat agggggcttg gtctttatct tgtctttgcc cttgattccc atatccattg
     9901 ttgctatgca aaaacgctct aaaaggatca tgaaccatta ctggtcaacc tatatggacg
     9961 ttggcaatct atttatggac gatctcaagg ggctaaatac cctttattcc tatcaggcag
    10021 atgaaaggta tgaggaaagc tttgtcaata aggcagaggc ctttcgtaag gctaccatgc
    10081 agctcttggg ctttcagctg caagcggttg gctatatgga cgctgtcatg tatcttggca
    10141 ttggcttatc tggcttttta gcggttcagg ctctgtcagc tggtggtata tccttttttg
    10201 actttctctt ttttatcctg attgcaacgg aattttttgc ccctattagg gagcagggct
    10261 atggcatgca cctagtcatg atgaatacta aaatggcaga tcaaatcttt ggctttttag
    10321 atagcgttga ggctgttgac caagacaagg gagttgcctt accggccttt gatcgtattg
    10381 atattcaaga tttgtccttt tcacatgggg aaaaggcttt gctaagagac atcacgatga
    10441 ctatcaaaaa gggtgagcta acagctgttg caggtgtttc aggacagggt aagactagtc
    10501 ttgcacagct cctgttgaag cgctatcagg cagatagcgg tcagatattc cttggtgatg
    10561 tgacgattga tctggcttct aaacaggcca tcaatcagga aatactctac gtttctgacc
    10621 agtcaacgct gcttaatatg agtatttatg agaaccttgc tatggcagct cagctgacta
    10681 gaaaggagct gcttagctgg attgatgagc atggcatttt gagctttatt tactggctac
    10741 ctgatgggat tgataccatt gtaggtgaga atggctgtca cttatctgca gggcaaagac
    10801 agcaggtgat ttgtgctagg gccttattga gccagcgttc ctgttatatt tttgatgagg
    10861 ctacctcaag tcttgatgct gagaatgaag ctgctattca cagactgctt cagcaattgg
    10921 ctaaacaggc cattgtaatt gtcatcactc ataagatgaa atatttgaag caggctgatc
    10981 aggtgctctt tttaagccct gagcagtctg ctagcttggc tagcccaaga gagctttacc
    11041 gccatcattt ggcctatcgt caattagttg atacacaagt agaattggag gcaaatcttt
    11101 atggttaaga gtgattacag cacctaccgg ctagttttac gattgcttgc tatgatgaag
    11161 catttgctgg cttggatagc tctggcggtg atgtttgcag tgctgggctt tgtgcttacc
    11221 gttggcattc ctaccagctt agcctatctg ggcttagagg tgatggctgg tcatgctatt
    11281 acctttaaat ggctttatct atttgttgct atggcactgc taagggggct tgttcgttat
    11341 ggagagcatt attttgggca ttttgttgcc tttcatagcc tggcagcctt tcgcaggatt
    11401 gtctttaaaa agctaagagc actctcgccg gcacgcttag acagtcagga cagcgggcac
    11461 ctgttaaaga tgattggcga ggatattgag gccttggagg tcttttttgc ccacacgctt
    11521 gcccctattt gtacggcgtt tatttcagct agcttgatgg cctattacct ttggcaggtt
    11581 agctggaagt tagccttggg ggctattgtg acctatgtgc ttttggctgt tattattcca
    11641 gtgtattttt caaacgtcct tcaatcactg ctcaaaaagc aaaatgaagg gcgcagggct
    11701 tatgtgtcaa gctttttaga gagtctcaga tctgttaagg atttgctgca atttcaaagc
    11761 attgagaagc gctttaagct cttatccaat cagagcaagc atgttaatgc gcttgatcgt
    11821 caggtggcac aggctcaatt tttacaaatg gcgataacct ttttggctct tggcttgtct
    11881 attttgacct ttgcttatgt tactcttttt gagctgagtc agcagacggt gacgtttgct
    11941 ggtgggttgc tggcttttgt tgcctttaca gcctcctttg cacccttttt agaattgggg
    12001 cgtttgccgc ttggcttcaa gcgtgccatg aatgctgcta ggaatgtctt tcagctttta
    12061 gatgaagaag cgttagtaga taagggagat cagcgtattt cctcggtaac aaggattgct
    12121 gttgaggatc tgacctttgc ttatcccaag catcaggaga ctatttacca ccacttatcc
    12181 gtcgcttttg aaaagaaagg cattatcggt attcagggag agtcaggctc tgggaagtca
    12241 actctgatga agatcattat gaaatggtac aattggcaag ctggtcatat tttcctgagt
    12301 gaggttgaca gtcaaacgct aaatgctgct tccctacagg ctaactttgc ctatgtccca
    12361 cagaatgcgc agctatttca gcaaacactt cgtgacaata tcacacttgg tcgtaaggac
    12421 atttcagatg atgatatcat ggaacttgct gaggcctgtg gcatgaagga gcgtatccta
    12481 gcctgtgatg aggggctaga taccctagtg agaggatcag cagacttttc agctggtgaa
    12541 gcccagcgct tggaattgat gcgggctcta ttgaagcggg cggattgcta tatttttgat
    12601 gagccaacat caaacttaga ttcgctgaat gaagccatct ttattgattt gattaaaaag
    12661 cattgccggg gaatggtctt tttgatttca catcggccat ccaccttggc ctgtgcagac
    12721 cagctatttt gtgtgagaaa tggttttttg aaggaggtaa acaatgaaag ggttaaccat
    12781 taaagatatc atgacaacag gcgcctttgc cgccctctat ttcgtttgtg tggggctagg
    12841 agccatgctg agcattctgt ttgatcgctc aggcaatatg ctctatgcgc cagcctttgc
    12901 ggccttgctt ggcgggccag tttatatgct attaatcgct aagctgcaga cctttggacc
    12961 gataagccta gtaggaatta ttatgggaag ctttttcttt ttgacaggtc atttttttgc
    13021 ttcaatgcta ccagctattc tttttggctg tttggcagat ggcatagccc ttttaggaaa
    13081 atatcaatct agactagtga atctcttgtc ttatcttgtt tttgcctttg ttaacagtgg
    13141 tcctattatt ttaatgtggc tgttgaagga cgcctatatc cagagtcttt tagcgcgtgg
    13201 taaggacatg gcatatgtta accgtatcat gtatgacttt accgttgcaa atgtcagctg
    13261 gtttgttggt gttgtccttc tttgtgcctt agtaggtggc ctttttggtc aatacctgct
    13321 gaaaaagcat tttgctaagt caggaatgct tttatgaggc ttgatgttcg cacaaaattg
    13381 ctcctgttaa ttctagccaa tgcctgcttc ttttttcgga ttgatggctg gctggggacg
    13441 atgattatag gtgttttgct tggcattttg ttttggcttg gtcaagggcg tctggcaatc
    13501 ggtatgacac tgctctatgc cttactgctt gctttgtctg tattgccgct tcatgtgctg
    13561 ccagcctatc tgtttaggct gctgagcttt gcagctgttg ctggtcaatt gctttaccca
    13621 tctgtgcttg ctgctttgat ttttgtcaag acaacgactg cctacgagct tgtgcatggg
    13681 ctgcgaaaat ggcatgtgcc agaggtttgt ctgttgactc ttgctgtcat gctgcgtttt
    13741 ttacctaaga tcaggcaaga aggaaagatt attcggcaat ctctgaaaat caggggcatt
    13801 ttcttggaca gctgggctat tgtcagacag ccaaggcggt atatggagta tctcttggta
    13861 ccgctgttga tgtcattgct gagaagtagt caggacttaa ccattgctag cctaacaaaa
    13921 gggctagcaa tcaaaaaggg agcaagtgag tgcttcgtat cacatctatc atggaaggat
    13981 tggggggtac agatttggat atttgtgacg atagcctaca tggttctcca gtgatcaagg
    14041 caaagcagct gcagttttcc tataccaatc gtaggcagac tgcctgtgag ctcagggatt
    14101 gtcagataga ggcaggtcaa tttatcgtgc tttgtggtca gtcaggctca ggcaagtcaa
    14161 cctttcttaa gctgctcaat ggcttgattc cagactattt ttcaggacaa ttacaaggaa
    14221 gtctgaaagt actgtctcat caggctggtc aggctagtgt tgaagtgctg tcaaggcagg
    14281 tttcctctgt ctttcaaaac ccagccagcc aatttttcta tcgtgaggtc aagcatgagc
    14341 ttgtttttcc ttgtgaaaat caaggcttag agccagctct tatccttgag aggctggata
    14401 ccttggcagc tgattttgac atcaaggact tactagaagc agatatgctt aagctatctg
    14461 gtggtcaaaa gcagcgggtg gctattgcag cagctatcat gcaagggaca gctatcatgg
    14521 tttttgatga gccaacagcc aatttggacc atgctagtgt agcagcggtc aaggcttatt
    14581 taaagcagct taaggctgct ggcaaaacca ttattgtcgc tgagcaccgc ttgcattatt
    14641 tgctggattt ggcagaccat ttttactatt tttcagctgg taggctagag cgcgtattaa
    14701 gccccaagga tctgctagct ttgccagatc aggaacgtga ggagctagga ctaagacgat
    14761 gtgagttgac tgctgtgact aaggctttgc gggcaaaaac tgtttttgag cattatgatc
    14821 cagagcatgc cttgcaaatc aagcagctag aggtcaaggc aggcagcagg gttttgtatc
    14881 acctcaatca gctcagcttt ggtgcagggc aaatcactgg cattaccgga gctaacggtt
    14941 tgggaaaatc gcagttggct ttatatctgg caggtatttt tgaagcaaaa gaggccaaga
    15001 tcagctatct gggtgtcacc ctgcctgcta aggacaggct ttcaatcaca agcctagtgt
    15061 tgcaggacgt tgggctacag ctattttcgg agacggtaga aaaggagctt aatctaggtc
    15121 atcatagaca tcaggctact gatgatttgg tgaataggct tgggctttct cagcttctag
    15181 acaagcaccc tgccagccta tcaggtggtg agcagcaaag ggtgatgatt gctgccagcc
    15241 tcttgtctga caaggagatt gtcattcttg atgagccaag cagtggctta gatctgctgc
    15301 aaatgcaggc tctggttagt cttttaaagg agctaaagca gcaaaaaaag gtagtgattg
    15361 tcatctctca tgacgaggaa ttactggatc aagcctgtga tagtatctat cagttgagca
    15421 ggtaaaggcc tagccttgct caagcggtct ggtgctgtat tggtgatggc tttatcgctc
    15481 cttggagcag caggtgttcc tgcttgatct gataaccact agctgcgatt gaccaatcac
    15541 aagccgccaa ctcttgacaa gctagcagta gctatcacaa ttctagggca tatcttggcc
    15601 tagcaagcag tgctgtattg tttatatgcc actcttcatc ttttagttag gccgtcctag
    15661 cggccgcact aagggtgtgt taggatcggc taatacctca aggcatctac agtaagaaaa
    15721 cgagcctctt cctttttgga gaggctcttg atttttgata taataatgaa aaagaaagcg
    15781 aggttgagat gctgttaaag agttcgattg ctaatttgaa gggtcttggt ccaaagtcag
    15841 ctgagaaatt tcaaaaatta ggcatttatc agatcaagga cttgctactc tattatcctt
    15901 ttcgctatga ggattttaaa agcaagtcag ccttagagct tttagatggt gaaaaggctg
    15961 tccttacagg tagagttgtg actccaccaa gcgttcaata ctatgggttc aagcgtaatc
    16021 gcctgagctt taaattgaag cagggggagc ttgtgattag tgtcagcttt ttcaatcagc
    16081 cttatctgct tgagaaaatc gtcttggatc aggaagtggc tatctttggt aggtgggatc
    16141 aaaaaaaagc agccttgaca ggtatgaaat tgctcatgac cttagaagat gatttgcagc
    16201 cagtttatca tgtggcgcag gggatcagtc aacccaccct gattaaggcg atcagatcag
    16261 cctttgatag cggtgcctta gctcagctgg aagaaaattt accagagccc ttgattcaga
    16321 aataccgcct gctgccgaga caagctgctg tttatgccat gcattttcct aaacatatgg
    16381 aggattataa gcaggccctg cgccgtataa aatttgaaga atttttctat tttcagatga
    16441 atctgcaggt tttaaagctt gctaacaagg cagagggcaa tgggttagcg attccttttc
    16501 atcagcaggc agtggcaaaa aagattgctg ctttgccctt ttcactgacc agagctcaac
    16561 aaagaagcct ggaggaaatc ttagcagata tgacctcagg ggctcatatg aaccgtctgt
    16621 tgcaggggga tgtcggctct ggcaagacag tgatcgcaag ccttgccatg tatgctgccc
    16681 aaacagcggg atttcaatcg gcactcatgg tgccaactga gattttagct gagcagcatt
    16741 acgatagtct ttgtcagctc tttccagatt tgtctattgc cctgttgaca tcgggtatga
    16801 aagcagctga aaaaagagca gctttatcgg ctattgctga tgggtctgtg gatatgattg
    16861 ttgggacgca tgccttgatc caagacgcag tgacctatca taagctaggg ctggtgatta
    16921 ctgatgaaca gcaccgtttt ggggttaatc agcgtcgctt gtttcgcgaa aaaggcaaca
    16981 atccagatgt tttgatgatg acagctactc ccatacctag aaccctagcc ataactgcct
    17041 atggtgagat ggacgtttcc attattgatg aattaccggc agggcgaaag ccaatcatca
    17101 ctcgctgggt caagcatcgg caattagata gtgtgctggc ctgggtaaag accgagcttg
    17161 ctaaggggac acaggcctat gttatctctc ctttgatcga agaatctgaa actctagatt
    17221 tgaaaaatgc ggtagcttta gaggctgagc tgaaggatta ttttaaagct tcagctagtg
    17281 ttgccttgat gcatggcaaa atgaaggcag acgacaagga gatgatcatg cagcgcttta
    17341 aggctaagga gattgatgtc ttggtgtcaa caaccgttat tgaggttggt gtcaatgtgc
    17401 caaatgccac catcatgctg atcatgaatg ctgaccgctt tggccttagc caattgcatc
    17461 agttgcgtgg tcgtgttggg cgaggcagca agcaatccta tgctattttg gtggcagatc
    17521 ctaagacaga ctcaggcaag gagcgtatga ccatcatgac aacgactaat gatggctttg
    17581 tgctggcaga ggctgacctc aagctgcgtg gctcaggaga gatttttggg acccgtcaat
    17641 caggtttgcc agagttcaaa acagctgata ttgtagagga ttatcatatc ctagaggagg
    17701 caagacgagt cgctgctgag attgttgcag ctaaggattg gcagctggac cctagatggg
    17761 ctccgatttt ggctaatctt cgtgtcgctg atcagtttga ttagatgtga ggctgacttg
    17821 ctggacagag ctaatataaa aacacgacaa gaggttctta gctgaccgag tcgtgctttt
    17881 tgtgctatag atgaggagta gtagcctgtg attataggag agcttagcct tcgatataat
    17941 ccttcagctc ttgacctgta agcccagcgt tgagggcgat gagcaatttt aacctggcct
    18001 taggggcatt tagctccttg acaaacataa caccagccct ttttaagctg gcaccacctc
    18061 cgcgataagc ataaactggc tctgctatgc cattgaagca gcgcgagacc aagacaacag
    18121 gaatcccaga ggcgattaat ttttcgagct cagatactgc taggggagga acatttccag
    18181 cgccgagggc ctcaatcact agtccctgaa tcctatcagg tgtcaaaagg cttaaaatac
    18241 ttccatctcc cataccagca taggccttga taatcggaac tgtgccagaa atatgacgaa
    18301 gctcaaagcg aacccttggc tcagcagtct taaagaacag taaatcgtcc ttcatgacga
    18361 ctcccaaagg gccatgagtc ggtgtttgaa aggtcgaaac attggtggta tgcgttttgg
    18421 tgacatactt agcggcatga atttcatcat tcatcacaac cagcaccccc ttgcccttgg
    18481 ctttctcatg gctggctacc ctaagcgctg ttaggtagtt atagatacca tcgcttccaa
    18541 tctcgttggc cgagcgcata gcacctgtga taacaatagg caactctaca ggcagcacca
    18601 ttgtgtctag aaaataagca gtctcttcta aggtatctgt accatgtgtg atgaccactg
    18661 catcaaactg actagccctt tgttgaatgt aatgatacat cttgagcatg tggtgagggg
    18721 tgatgtgcgg gcttggcaga tttaaaaaat ccacaacagt taggtggata tgctccaggc
    18781 taaggccaac ctgattcatt ggattgtttt gatttgggct caccttgcct gcttcatcag
    18841 cctgcattga aatggtgccg ccggtatgta agacgaggat ttccttcatt tgatactcat
    18901 acttctttca atttatgata taatttattt tatcacaaat agaagagaga acagaaggat
    18961 ttgacaataa aagcagtctt tttcgacatt gatggaaccc tgcttaatga tcgaaaaaat
    19021 gttcaaaaaa cgacgcaaag ggctattcag caattaaaaa aacaaggtat tatggttggg
    19081 ctggcaactg gtcgtggacc tgcttttgtg cagccctttt tagaaaattt tggcttggat
    19141 tttgcagtga cctacaatgg tcaatacatt ttgacacgag acaaggtctt gtatcagaac
    19201 cagctgccaa agtcaaccat ttataaaatc attcgctatg ctagcgataa aaagcgcgag
    19261 atctccttag gaacagcttc aggtcttgct gggtctcgga tcattgatat gggaaccagt
    19321 ccatttggtc agatggttag cagtattgtg ccaaggagtc tggtcaagac ggttgagggc
    19381 agctttaaaa acctcatcag acgctttaag ccgcaaagct tcagcaatct tgttaccatt
    19441 atgagagagc cgatttatca gattgtcttg gttgcttctg ttgatgacac ccaaaaaatc
    19501 aaggaaagat tcccgcatat caaggtaacc agaagcagcc cttattcctt agatttgatt
    19561 tctagcgggc agtctaaaat caagggcatt gaacgcttgg gcgagatgtt tggctttgag
    19621 ctctcagagg tcatggcctt tggcgactct gataatgact tagaaatgct ctcaggcgtt
    19681 ggtgttggtg ttgcgatggg aaatgctgag gcagtggtta aaagcggtgc tcactttaca
    19741 acagcttcaa ataacaatga tggtatctct aaggcgctgg cgcattatgg cttgattcat
    19801 tttgatgtgg aaaaaagctt taaaagtcgc gatgataatt tcaacaaggt caaggatttc
    19861 caccgcctga tggacggaga cacgattgaa acaccaagag gctattcctt aaaggaggct
    19921 ggctatcgag cagattttaa ggtagaggaa cttgtggaat ttctttatgc agccagtcaa
    19981 ggggataagc atcgcttttc tcaggctttg atagacctcc atgctgccct tgataaggca
    20041 gctaagaagg tgcaggccaa ggagcaccca gagtcacccc tggttgggca ggttgatgct
    20101 ttgacagatc tgctttattt tacctatggc tcatttgtat tgatgggagt ggaccctcag
    20161 cccatttttg agaccgtcca tgaagccaat atggggaaaa ttttccctga tgggaaagcg
    20221 cattttgatc ccataacgca taaaattcaa aagccagatg actggcagga gcgctatgca
    20281 ccagagtcag ccatcaaaaa agagttggac aagcagcttc aaaaatcatt gcagcgcttg
    20341 gaaaaataag gctgtcttta ttttagaggc attaaaaagc accttgagct gtgagttgat
    20401 ctcctagctg ttaagcattt ggcctaacac ttggggtcac ttcacttatt agctcagggt
    20461 gctttttgat gtagactaga caccctcaat aaaagggccc ttaagtctag ctagtggtaa
    20521 ttagtatatg agagcagtag tcctttagta gccttgtgag ctgaggctaa gggctaggta
    20581 tggttacttc acttaggctg caaatgcttc tgacagctga gagaattcgt cttgctacag
    20641 ggttttgtca tgctctcgaa ccactaatag gtcaaccttg gcatgacgaa ggatatattc
    20701 agatgatgat ccaatcagca accgctcaaa ggtgttaagc ccagttgccc caaccataat
    20761 caaatcaacc tcttctttgt cagggatatc gtgcgctaat agcgttttgg gattgccaaa
    20821 ttcaatcacc tgcttgacct cagtcagccc tgcctcgcgt gcttgttttt caaaatcccc
    20881 caagacctct ttagc
//
LOCUS       DARYXW010000032        20225 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.032, whole genome shotgun sequence.
ACCESSION   DARYXW010000032 DARYXW010000000
VERSION     DARYXW010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20225)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20225)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20225
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.032"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            137..421
                     /locus_tag="TV191_000935"
     CDS             137..421
                     /locus_tag="TV191_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3310 domain-containing protein"
                     /protein_id="HEL1507463.1"
                     /translation="MLMEDTFKKIKELEAACQDRTDNIKKPSHYQGRHGMEAIDVVKN
                     FAACPEHEEGFYWGNAVKYLLRYHAKNGVEDLKKARQNLDWLIEKLEEVE"
     gene            446..658
                     /locus_tag="TV191_000936"
     CDS             446..658
                     /locus_tag="TV191_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000010060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507464.1"
                     /translation="MSFRLSWEINGQTVEVIGDYKTLKAAYDSIKVHVKDRDKFASPY
                     YRIWQKGAVHFVDYGKHNAFYKIEER"
     gene            663..863
                     /locus_tag="TV191_000937"
     CDS             663..863
                     /locus_tag="TV191_000937"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507465.1"
                     /translation="MMDTETLEAVYDALQLSLPKIIDMLKAASATRDDAYKEGVLDGA
                     DLIADTVIKAIGQMIDPEADHG"
     gene            856..1083
                     /locus_tag="TV191_000938"
     CDS             856..1083
                     /locus_tag="TV191_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507466.1"
                     /translation="MAKDDFLTGFVLTLLAACVFAAGFVIGSDCSSEHYEQQMTDLRM
                     QLVSTQQQLKQSREQNQRQTKRIAELTGNGG"
     gene            1094..1783
                     /locus_tag="TV191_000939"
     CDS             1094..1783
                     /locus_tag="TV191_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002814908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEL1507467.1"
                     /translation="MEIKCGNCLQLLTELTDGSIDMVITDPPYNISVKNNFATMGRTG
                     IDFGDWDKGFDLLSWIDIASRKLTKNGGMVIFNDWKNLGDIARHCEKTGLVVKDIFRW
                     VKDNPMPRNRDRRYITDSEYGIWVVRKNSKWVFNRKSEKYDRPEYRYPIVAGLEKTQH
                     PTQKPVALMRDIITRHTTKGAVVLDPFMGSGSTGVACLLTERDFIGYELNKDYFNIAK
                     KRIAELTGNGG"
     gene            1787..1969
                     /locus_tag="TV191_000940"
     CDS             1787..1969
                     /locus_tag="TV191_000940"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507468.1"
                     /translation="MPELINTADLQTPIEALENNLDFFKSFYNDERFEDMENAKKLIE
                     RYEKAISILTEVQNES"
     gene            1959..2117
                     /locus_tag="TV191_000941"
     CDS             1959..2117
                     /locus_tag="TV191_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507469.1"
                     /translation="MKVKDLHKVLAKVDPELEVWINEKDGGVITKAKNVMTWNEHPNK
                     FFINAETQ"
     gene            2136..2717
                     /locus_tag="TV191_000942"
     CDS             2136..2717
                     /locus_tag="TV191_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEL1507470.1"
                     /translation="MNIEEAIKYFEDKRKDYIVSPSVIHVSTVEVINILKQIKLDKPK
                     PEIPQFVADWIEGHKADYITWEKADKADFVFRCINDLFNFGADMHTYDFDVSYEISKW
                     TQEHAYGFIVAVLFGYTIKKEKLYIVEIPNPNSGIEHKHIALARLANGKLGFSEIIDT
                     DFYSREDVRLTESEIRKDFDWAWERGFAKGVKE"
     gene            2714..2881
                     /locus_tag="TV191_000943"
     CDS             2714..2881
                     /locus_tag="TV191_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507471.1"
                     /translation="MNKSEIKNLVDRLSDLIDKCENDFEAMVFNPDGTFDLLLASHSA
                     LSKVLRGEVTE"
     gene            2878..3093
                     /locus_tag="TV191_000944"
     CDS             2878..3093
                     /locus_tag="TV191_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507472.1"
                     /translation="MKSYQKRFVEEYRQLTQRLSKLDKMLKKYAQGTLGFEPDCPIRL
                     LQEQRRVMSEYVDILEARAKFEGVDLE"
     gene            3167..3604
                     /locus_tag="TV191_000945"
     CDS             3167..3604
                     /locus_tag="TV191_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEL1507473.1"
                     /translation="MGNIPTPKANNFLEELKTIPDLIETLERDANLMSRSLIKSPQWS
                     DMRVSGGVKQSQEDKNIKMLHMVSYYSDQIERLKDRRQEMANLIVQSMGICESHVLLT
                     TYLDCDGDYERARERLNIGNRNKYFMFVRRGKESLELILKNTN"
     gene            complement(4109..4486)
                     /locus_tag="TV191_000946"
     CDS             complement(4109..4486)
                     /locus_tag="TV191_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEL1507474.1"
                     /translation="MLIYPATFTQDTDYIMVTFPDVPEAITQGKDFQEAYEMAVEVLG
                     FALEDYTDYPKASSVSDLKEQYRDSDIALIGIDMIAYMKKYHSKKVRKNVTIPEWLNK
                     AAEDENLNFSQVLTEALELKLQA"
     gene            complement(4538..4723)
                     /locus_tag="TV191_000947"
     CDS             complement(4538..4723)
                     /locus_tag="TV191_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEL1507475.1"
                     /translation="MPMTPKQMIKLLKKNGFYEVSQNGSHKKFRDNNGHQTIVPLHNK
                     DLGKGLEDTILKQAGLK"
     gene            4839..5174
                     /locus_tag="TV191_000948"
     CDS             4839..5174
                     /locus_tag="TV191_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEL1507476.1"
                     /translation="MRPQKLTIAGGRRTTVDYDDRSAEYRDYNRNRWKYDRKTKQFYN
                     SKIWRETSKQVLLQSDYICAMCGGEATMTDHIVSVKKDWNKRLDWNNLQASCKACNDC
                     KAIRERRKT"
     gene            5337..5804
                     /locus_tag="TV191_000949"
     CDS             5337..5804
                     /locus_tag="TV191_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HEL1507477.1"
                     /translation="MGRNLKLVETTKKHLTKEEKIVRETAQNKASDGLKKLQKTPPEH
                     FNNVAKYEYRRIIEDLQNLPLRNLDRGLLELYCTWYAIYKETSRKLDEVGYFTNDPDK
                     GIIPSPLILTLEKATANIRSSASQLGLTVDSRMKMFIPKEEEKPKSIFDKFGG"
     gene            5819..7573
                     /locus_tag="TV191_000950"
     CDS             5819..7573
                     /locus_tag="TV191_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HEL1507478.1"
                     /translation="MTIEYDYSAIGDIYKDDAFYYAKMVVDEEIKASKKVFKACLRHL
                     NDLKKIDDDNFKFIYLPKKAIDPIIFIELLPDVKTGKPYPLAMFQKFIIGNLYGWRKK
                     TDHSLRRFRKAMISVARKNGKTILIAGILLYEFLFGHNPSMSRQLFCTANDRTQAKIA
                     WDMAKKQLSSLRAKDADVRKATKIVRDELKNLHDESYIRALSRDTGAVDGFEPYVGVL
                     DEFAASKTNEMLELLESGQGQLDNPFILIISTAGMDLNVPMHTIEYPYITKILDEEIV
                     DDGYFGYVAEQDNEGEIKDESNWIKSNPILEVEALHDKLMDYLRTRRRVSLETGEINK
                     VLIKNFNMWRQSSEESYIDKQSWELARIDKPDTHKRRVWLGVDVGRVSDLFAITPVIM
                     MDDFWYIDSFSFVATKYGLTAKEKRDGVSYSNLERQGYCEITTLESGVIDDERVLEKI
                     EEMVYSNDWEVNGICFDPYQFGTLLTMIEKRHPEWPLIEVSQTTMVLNMPTKQFRDDL
                     KNGKIKHSGNPLLTMAVNNAYIKTDNNGMRIDKNKNSNKIDPLDAALDGYAVCYLEPF
                     DGSGYWTSEKILGGETLF"
     gene            7570..7740
                     /locus_tag="TV191_000951"
     CDS             7570..7740
                     /locus_tag="TV191_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507479.1"
                     /translation="MIGFILKNIHTLILLAGLGLLMYGLFLFGDKVGFIASGLILIFL
                     AIYVDSVGGKHE"
     gene            7733..7999
                     /locus_tag="TV191_000952"
     CDS             7733..7999
                     /locus_tag="TV191_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507480.1"
                     /translation="MNKRIKKKRKLETAVVMLVAENAMQAEVLRNQNRQIAELRSIIQ
                     QNAQATNREFAAVKSATLDNQAAIKKIGDEVYYIKQNYKRKWRK"
     gene            8033..9253
                     /locus_tag="TV191_000953"
     CDS             8033..9253
                     /locus_tag="TV191_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000007730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL1507481.1"
                     /translation="MSFFQPLGSSKVSYDDYVSSVLAGDVSQKYLGVSALKNSDILTA
                     TSIIAGDIARFPLVKKDVNGDIIHDEDINYLLNVKSTKNASARTWKFAMAVNAILTGN
                     SFSRILRDPKTNQALQFQFYRPSETTVEETDNHEIVYTFTDMLTAKQVKCFAHDVIHW
                     KFFSHDTILGRSPLLSLGDEIDLQTGGINTLIKFFKDGFSSGILKMKGAYISGEARKR
                     ARVEFEKMREGAIGGSPLVFDDTQEYTPLEIDTNVLQLITSNNFSTAQIAKALRVPSY
                     KLGVNSPNQSVAQLMEDYVTNDLPFYFDAITSELGLKTLSDKDRRLYRIEFDTRSVTG
                     RNVDEIVKLVNNQILTPNQGLVELGKQKSTDPNMDRYQSSLNYVFLDKKEEYQDKVGI
                     KGKGGEVNAKEDKS"
     gene            9231..9896
                     /locus_tag="TV191_000954"
     CDS             9231..9896
                     /locus_tag="TV191_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HEL1507482.1"
                     /translation="MPKRINLKGPLIANNSQEVYDYYGMEAASAKSIIEQFPEDNSDI
                     VLEVNSNGGLVTVGSEIYTALRNYKGKVTAEITGMAASAASVAVMGADKVVMSPTAQM
                     MVHKALFKWVSGNSDDLDKASNALKSSDKAIVSAYVAKTGLSEDAIMDLMRNETFMSA
                     QDAVEKGFADEVMSFEAVASIDNSMLPQAVIDDYYRSRNKRKQEISNMLLEIEKEEIL
                     RGL"
     gene            9921..11108
                     /locus_tag="TV191_000955"
     CDS             9921..11108
                     /locus_tag="TV191_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HEL1507483.1"
                     /translation="MFEEKIKEIKANIANLNQAIATKTTEVKNALESDDLETARSIKA
                     EIEEAKANLAEAENDLKLYEASVEKGGAENTGGKEVPQETKTYRESVNEFIRSKGTVT
                     NEGLRFEGKDEVLIPLNQTTPVDPKTDGVKKTDVKPVSSEEILYTPAREVKTVVDLKQ
                     FTSIHPAKKESGKWPVLQRATEKMVSVEELEKNPKLGKPQFKNVEWEVKTYRGAIPLS
                     QESIDDADVDLVGIVAETIGQMKVNTTNDAIAKVLKTFEAKAGVKTLDDIKKILNVDL
                     DPAYNVSFIVSQSFYQTLDTLKDKNGRYLLQDSITSASGKVFLGKPVFVLSDDVIGED
                     SAFVGDFKRGVLFADRKDLGLRWADNEIYGQYLQAVLRFGVAKVDDKAGYYVTFKPEQ
                     LPS"
     gene            11253..11555
                     /locus_tag="TV191_000956"
     CDS             11253..11555
                     /locus_tag="TV191_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEL1507484.1"
                     /translation="MAVSKELLDSVKLYCKIDFDFDDDIIKEMIESAQEQICFAIEDG
                     STPEKFKGHAKFNLAVKKQVKEEYDHRGLSADSFRYPLANGVLNIIHQLRLRGDDS"
     gene            11552..11899
                     /locus_tag="TV191_000957"
     CDS             11552..11899
                     /locus_tag="TV191_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HEL1507485.1"
                     /translation="MITRKMNVRITIFSQSGGQNEDGEVVSAVRKDLYTCWAEVLKTQ
                     LRDFNYQSKYQNASNLPTNKDTKVFLIRYNPELSIDNTMFVEFGKRIYKIDKIESDES
                     GKDIIMISGVSMS"
     gene            11896..12273
                     /locus_tag="TV191_000958"
     CDS             11896..12273
                     /locus_tag="TV191_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEL1507486.1"
                     /translation="MTKGLDEILANLTKLEVKAPKTAKAAVTEVAKEFEKALKANTPV
                     YEIETDERLQEDTVISGFKGANVGIVSKEIGYGKATGWRAHYPNDGTIYQRGQDFKEK
                     TINQMTPKAKQIYAAKVKEGLGL"
     gene            12270..12740
                     /locus_tag="TV191_000959"
     CDS             12270..12740
                     /locus_tag="TV191_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507487.1"
                     /translation="MIAETAAYKLLSNDKTLNELLDRLRGGPFKNGFKQGIFTYDIPD
                     NPVDLRKVDLAPFMRINTTLDGPADYADDEILCNEQRITINFWCKTASEADQISKCID
                     DILKKGGFERYTANEKPRYKDSDIDLLMNVRKYRYFDFYLKERGKNGKSKIWTT"
     gene            12712..13302
                     /locus_tag="TV191_000960"
     CDS             12712..13302
                     /locus_tag="TV191_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1507488.1"
                     /translation="MGKVKFGLRDFQYAVLGEDDNVATKKGGIKKLPGMKSAKLDITN
                     ELVTVSADDGPYVVLSGGITETKLEIEVLDLTTDARKDFFGIKVAAGVEKYNKNLTPN
                     NVACIFRTSDENGKAIWVGLLKGKFNLPGMETQTKEGSPNPKADTVTGNFVSRGTDGD
                     VLVIGREESHEFNYEAFAGFVFAGATDIKKGENFEM"
     gene            13354..13680
                     /locus_tag="TV191_000961"
     CDS             13354..13680
                     /locus_tag="TV191_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507489.1"
                     /translation="MYEITLKKGGVDKVFSKDFINVEDNLLAVEHQVRQSAVFSDEKR
                     RLDSKAHRKLNESYLQMFVDMYAGQFTVDDLKQSDMSVLNTLNDLYIAALGGEQEEDE
                     SEKKEQ"
     gene            13728..13877
                     /locus_tag="TV191_000962"
     CDS             13728..13877
                     /locus_tag="TV191_000962"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507490.1"
                     /translation="MKNGYTILDIKKMRLSDIELMVQALEIETVEKEEVIETTLDKAF
                     PFLFG"
     gene            13890..17813
                     /locus_tag="TV191_000963"
     CDS             13890..17813
                     /locus_tag="TV191_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HEL1507491.1"
                     /translation="MGNIGDLVATATLDISPFMSNTRNLKTYMKGLDNSLKAVEKSFQ
                     GHGGRIKGLKAVYAETGSALKGYQELLKTQSQKYSDLKKEIGDVNNATAEQKQKLIGA
                     KSAMLETAAKVTELQNRLRALATETSVFTRFGKAAEKIGGKMKSLGDSVAGVGAAFTR
                     GVTAPIVAGAGYAIKAAVDYETAFAGVKKTVDETATVSYAKLSQGIRQMAKELPASAV
                     EIAHVAEAAGQLGIKTGDILSFSRTMIDLGESTNLSAEEAASSIAKIANITGLTSKEY
                     SRFGSSVVALGNNFATTERDIVAMTNRIAASGKLAGLTNQEMLALATAMSSVGIEAEA
                     GGTAMTQTLSAIETAVINGGEDLTKFAQIANMSSADFARAWKEKPIVALQEFIKGLGQ
                     LDKKGESATKVLDELGLSGIRQSNMLKSLGLASETLGKALGISNKAWQENTALTDEAN
                     KRYETTESKLKMLKNEVNDVAIEFGGPLVDALRNGLEAGKPIIQMAADLAKQFNSLDK
                     EQQQQIIKWGLIAAAAGPALSIFGKGVGIIGSTIQGIGKMSQGLGALSGWLRTFKTGA
                     AAASAGAEAATASMGGMAGAVALLSNPVTWGVLLGGAAIVGIGLIADSMYKAQKRTEE
                     WGTAVSATEANALSNFKKKVDETNTSLQMFEAGAGSVKKVTEAFDDLVGSIEKLAQSK
                     LDKNINLAKKLGLSEETINALKSKTESVVNNVKSMNTQIKAIMEKHNGDMSQLSSAEK
                     ELVLRNQREMITAQLDLMKFSASEKKALTAALNNELDALNARQLEKVSENTVKMLDKE
                     NSAYKTKKAELKEILKQFGSDTSKLSAEELAARQEVLNRLTELNMQHNLKTKALNDQY
                     LAIQRERVQRLKESGKSQEEIHQGISQMASDMAQKLGISYDDAYRKLAYYTEKSGETL
                     KVLSRNTANATAEVAAANAQWDSLFTSDNPQQSLNELLSTAEGWNSFEIMVKNADVEP
                     TGRAALAEMLVAGGQWENMTLEQKKLVVDGQQAMIEIFDSKELLAQWQALTPEEKVLL
                     AKNLTQEPTMSAQQALDSVKQTVPADVNASDKTAGETQSAQNKIDNVKQRVPADVKAS
                     DKTGPDVASADRAVNSPKQKSPAVIRAQDNASGVAEGVIGALARIPRSVTTTITTFVR
                     KIFGHEKGTDFHPGGLAMVNDQKGPLYKELVTLPTGESFIPSGRNVILPLPRGSKVLK
                     ASRTKQLFPHYASGIGFDDTKIASLTTRLKSVQDKGQVIINTDPQLAELIKLLKDRDD
                     RNVTNNYTVNATNSSSSEDMFSQENMRRLLRELAYYTNGEGGRLA"
     gene            17813..18520
                     /locus_tag="TV191_000964"
     CDS             17813..18520
                     /locus_tag="TV191_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEL1507492.1"
                     /translation="MRYIEFNGTKSNDLGLLLERERSIKSTNNDIDLIEVAGRDGVLI
                     KDNERLKAVEQDFPFSLVGDVTVNQQKISEWLHVKGWHDLALSWDKDYIYRASVVNLF
                     EIDEILKQFGRLKVNFLIHPIKYLKTGKQEVPLVNGGTLQNPGNVQAKPILKIKGTGN
                     GVLTINDFETGLENVQGELVIDMERHLVYKDVLSAWDNIVRTEHHRMPLFDIGQNKIS
                     WTGNFTITAVPNWGVKV"
     gene            18517..>20225
                     /locus_tag="TV191_000965"
     CDS             18517..>20225
                     /locus_tag="TV191_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1507493.1"
                     /translation="MIPVLYEAKETKFRTFGLGEIADAYEVKATRERNGNYSLYIKYP
                     LDGAFAHLFKEEMKIKSDAGRRTKWQTFEINRVLRNSKEHIEIFARHISMRTQDIALK
                     PFVSGSSIDAESALEVWRDNLVGDDTFDVKSDILTLGSFNWEVDKIGNARGALGGVAG
                     SILDVYGGEYEFDNRTIILHKQMGRKTPTVLEYGRNIVSVEEERLLDGNYTSIYPYVR
                     YTPQPKPQEEASGKPHIGEHEKPEEQLVTLPEFIIDGQYLDLYAQRRIQMVDLSSHFN
                     DDKKEPTVEEIRKLAQKYLKDNNVGAPKISIEVDYIDLSQTLDYQDFRVMEEVELCDI
                     VPLYYPKFGITTETEKVVEIVYDVYTDSNHTIKLGTIGQSISKSLTGGVTQRIETLEN
                     NQKVITNNQQQFELNLPKYLNDLNGTKIWYEKPDDNVEHKIGDFWFEKNGKYQRTWVW
                     DGNQWVKIIDTEDLNPNQRAFDEAMAEIEKLKQHQQQIDKRNQRELEEFRDTLKNLAL
                     PEEAIKKITEAIKVDDIPSIKQSFDDLKNKVSETSETARLNAEIIGTDGKTRYNKNLL
                     VGDP"
BASE COUNT         6878 a         3336 c         4583 g         5428 t
ORIGIN      
        1 acttacgcgg ttactgataa aagattgttt agggagcatg agttcgcaac aaaaagagaa
       61 gcgatgcagt ttattagaga gctagagtta gctaatgata agcgagcgac agaatattat
      121 ttgagagagt ggagagatgc taatggaaga tacgtttaaa aaaattaagg agcttgaagc
      181 tgcttgtcag gataggacag ataacattaa aaagccatca cactatcaag ggcggcatgg
      241 catggaagca atcgacgtgg ttaaaaactt cgcagcttgc ccagagcacg aggagggttt
      301 ttattggggc aatgctgtta agtacctttt gcggtatcac gctaaaaatg gtgttgaaga
      361 ccttaaaaaa gcacgtcaga accttgattg gttaatcgag aagttggagg aagtggaatg
      421 ataccaaaat ttagagtgtg gaagaatgag ttttagatta tcttgggaaa ttaacggcca
      481 aaccgttgag gttataggtg actataaaac actaaaagca gcctatgact caattaaggt
      541 ccacgtcaaa gacagagata aatttgccag cccatattat cgcatatggc aaaaaggagc
      601 tgtacacttt gtggattatg gaaaacacaa tgctttttat aagattgagg agaggtgatt
      661 aaatgatgga tacagaaaca ctagaagcag tatatgatgc tttgcagcta tccttgccaa
      721 aaataatcga tatgcttaaa gcagcatccg cgaccagaga tgatgcttac aaagagggtg
      781 tactcgatgg cgcggatttg atagctgata ctgtaataaa agctatcgga caaatgatcg
      841 atccggaggc tgatcatggc taaagacgac tttttaacag gttttgtact tacactttta
      901 gctgcttgcg tttttgcagc aggatttgtg attggatctg actgtagtag cgagcactac
      961 gagcaacaaa tgacagactt gcgtatgcag cttgttagca cgcagcagca gcttaagcaa
     1021 tctcgtgagc aaaaccagag acagactaaa cggattgcgg aattgacagg aaatggggga
     1081 taaaaaacac tacatggaaa taaaatgtgg aaattgctta caattactaa cagagttaac
     1141 tgatggatca atcgatatgg tgataacaga cccaccatac aacatatcag taaaaaataa
     1201 ctttgctaca atggggcgga caggtataga ttttggtgat tgggataaag gcttcgactt
     1261 gttaagttgg attgatattg caagtcgaaa attaactaaa aatggtggaa tggtgatctt
     1321 caacgattgg aaaaatttag gagatattgc aagacattgc gaaaagacag ggttagtagt
     1381 aaaagatatt tttcgttggg tcaaagataa ccctatgccc agaaacagag atagaaggta
     1441 tattacagac agcgagtacg ggatatgggt cgtccgaaaa aattccaagt gggtatttaa
     1501 tcggaaatcg gaaaaatatg ataggccgga atacagatat ccaattgtag ccggactgga
     1561 aaaaacacag caccctactc aaaagccagt agccctgatg agggacatca ttacgcgaca
     1621 cacaacaaaa ggggctgttg ttttagaccc ttttatgggt agcgggtcaa ctggagtagc
     1681 ttgtctactg acggagagag actttattgg atatgagcta aataaagatt actttaatat
     1741 cgcaaaaaaa aggatagcag aattaactgg gaatggggga tgaaatatgc cagaattgat
     1801 taacacagcc gacttacaga caccgataga agcactagaa aataacctag atttttttaa
     1861 aagtttttac aacgacgaac gctttgaaga tatggaaaat gcaaaaaaat tgattgagag
     1921 atacgaaaaa gctatatcaa ttttaaccga ggtacaaaat gaaagttaaa gatttacata
     1981 aagtgttagc taaagttgac cctgaacttg aagtttggat aaatgaaaaa gatggagggg
     2041 ttataactaa agctaaaaac gtgatgactt ggaatgagca tccaaataag ttttttataa
     2101 atgcagaaac acaataatgt taaccgaggt acaaaatgaa catcgaagaa gcgataaagt
     2161 attttgaaga taagagaaaa gattatattg tatcaccaag tgtaatacat gtatcgactg
     2221 ttgaggtcat aaatatttta aaacaaatta agttagataa accaaagcca gaaattccgc
     2281 agtttgtcgc tgattggata gagggacaca aagcagatta tattacgtgg gaaaaagctg
     2341 ataaagcaga ttttgttttt aggtgtatta atgacctctt taatttcggt gcagatatgc
     2401 atacctatga ctttgatgtg tcttatgaga tatcaaaatg gacgcaagaa catgcctacg
     2461 gttttattgt tgctgttttg ttcggctaca caataaaaaa agaaaagctg tatattgttg
     2521 agatccctaa tcctaatagt ggcatagaac acaaacatat tgcactagca aggttagcga
     2581 atggaaaact tggattttca gagatcatag atactgattt ttattcaaga gaagatgtcc
     2641 gactcaccga gtcagaaatc cgcaaagatt ttgattgggc ttgggaacga ggttttgcga
     2701 aaggtgtgaa ggaatgaata aaagcgaaat caaaaattta gtagatagac taagtgattt
     2761 aattgataaa tgcgagaacg actttgaggc aatggtattt aacccagacg gaacgtttga
     2821 cttattactc gcaagccatt ctgcgttgtc aaaagtgtta agaggagagg taacagaatg
     2881 aaatcatatc aaaaaagatt tgttgaagag tacagacaac ttacacaacg tttgtcaaag
     2941 ctagataaaa tgcttaaaaa atatgctcaa ggcactcttg gttttgaacc agattgccct
     3001 atcaggctat tacaggagca gagacgtgtg atgtcggagt atgtcgacat attggaagca
     3061 agagcaaaat ttgaaggggt tgatttggag taataaaaaa agacgtccat gcgaacgcct
     3121 tcatgattaa atacccaaca atattatatc atgaatggag agttagatgg gcaacattcc
     3181 gacaccaaaa gctaataatt ttttggaaga attaaagact atccccgatc ttatagagac
     3241 ccttgaaaga gacgctaacc taatgagtcg gtcgctcatt aagtctcctc aatggtctga
     3301 tatgcgagtg tctggtgggg tcaaacaatc acaggaagac aaaaacataa aaatgttaca
     3361 catggtcagt tattacagtg atcagattga gcggctaaaa gaccgtcggc aagaaatggc
     3421 taatttgatt gtgcaaagca tgggaatttg tgagagccat gttttgctaa cgacttatct
     3481 tgactgtgat ggagactacg agagagccag agaacgctta aacataggta atcggaataa
     3541 atactttatg tttgttaggc gaggaaagga aagtctagaa ttgatactaa aaaatactaa
     3601 ttagatacaa attgatacta cataatacta ataaccatgt tattatagta ctgttgaaat
     3661 aacaagaaga gataaccatt ttaccaattg actatttatt tagtcgctga ctttaactac
     3721 gatcaaactt gttattttac taaagcttag tagctttgcg ttaaaggtgt taaattactc
     3781 ggttgaaccg gtcgggtaag tcgcaaatat gaagagagtt gttgagacgt aaggaaatgt
     3841 catgtgcacg catcttatga tattgcaggt tcgaaccctg ccgtctcaat cagcgtcggg
     3901 gagacgcgac cccatacccc tttaaaggca gacacgttct gatgtgtggg tttttatgat
     3961 taaccgcaag tccaaaacca agggtcgcaa ccttgcttgt ggttagtagg gacaacggtt
     4021 gtaagtcggt tcgattccga ctgttcctgt gctagtcatc acatcgtgat ggctttttat
     4081 tatgcaaaaa agaaccacta agtggctctt atgcttgtag ttttaattca agtgcctctg
     4141 tgaggacttg cgagaaattg agattttcat cttcggctgc tttgtttaac cactcaggga
     4201 tagtcacgtt cttacgtact tttttagagt ggtatttttt catgtaggca atcatatcga
     4261 tgccgattaa agcaatatca gaatcacgat actgttcttt taagtcggaa acggagctag
     4321 cctttggata gtcagtatag tcttcaagag caaagcctaa gacttcgaca gccatttcgt
     4381 aagcttcttg aaagtcttta ccttgagtaa ttgcttcagg tacatctgga aatgtaacca
     4441 tgatatagtc tgtgtcttgt gtgaatgtag ctggatagat taacataatg attctccttc
     4501 gatcactgtg agataagcaa accatctggc aagcggatta ttttaaaccc gcctgcttta
     4561 gaatggtatc ttcaaggcct tttccgaggt ctttgttgtg tagaggaaca atggtttgat
     4621 gtccgttatt atctcggaat tttttgtgac ttccgttttg actgacttca tagaacccat
     4681 tcttttttag cagttttatc atctgctttg gggtcattgg catattgctt acctcacttt
     4741 ctatacttat attatacacg caataaacat ggttgtcaat aggtatgcgc aaaaaatgcg
     4801 tatttttgtt ttctattttt tattatggag gttagggtat gaggccgcag aagttaacaa
     4861 ttgcgggtgg cagacgaacg actgttgact acgatgatag gtcagctgag tatcgtgact
     4921 ataatcgtaa cagatggaag tatgatagga agactaagca gttttataac tctaagattt
     4981 ggagagagac aagtaagcaa gtcttattgc aaagtgatta tatctgtgca atgtgtggtg
     5041 gagaagcaac gatgactgat cacattgtct cagttaagaa agattggaat aaaagattag
     5101 attggaataa cttgcaagca agttgtaaag cttgtaacga ttgtaaagca ataagagaga
     5161 gacggaaaac ctaaacgtac ataaaaagta acatacgcaa tcattgttcg ggaaataccc
     5221 cgcctatttt ttaacggggc tatattgttc ggaaacttaa gaacgcgccc ttttctgtgc
     5281 aaaaaaatcc ctttttgaaa tttttgaaac tgtaaagttt gtgtaaagga ggtcttatgg
     5341 gaagaaattt aaagctagtt gaaacgacaa aaaagcatct tacgaaagaa gaaaaaatag
     5401 tgcgagaaac cgcgcaaaat aaggcgtctg acggtcttaa aaagttgcaa aagacacctc
     5461 ctgaacactt taataatgta gctaagtacg agtataggag aatcatagaa gacctccaaa
     5521 acctacccct aagaaatctc gatagagggc tattagagtt atattgcaca tggtatgcta
     5581 tctacaaaga aacaagtaga aaactagatg aggttggtta ttttacgaat gatccagaca
     5641 aaggcattat tcctagtccg cttattttaa cattggaaaa agccactgcg aatattagaa
     5701 gtagtgccag tcaattagga ctaacggtag atagtcgcat gaagatgttt attccgaagg
     5761 aagaagaaaa acctaagagt atatttgata aatttggagg atagagagaa agggggtcat
     5821 gacaatagaa tacgattatt cagcaatcgg cgacatctat aaagatgacg ctttttatta
     5881 tgcaaaaatg gtcgttgatg aagagattaa agcaagtaag aaggtcttta aagcttgtct
     5941 aagacatttg aatgacctta aaaaaataga tgatgataat tttaaattta tctatttacc
     6001 aaaaaaagca attgacccca taatttttat tgagctattg ccagacgtta agacgggaaa
     6061 gccttatcct ttagcgatgt ttcagaagtt tattatcggg aatttatacg gatggcgaaa
     6121 gaaaacagat cattccttaa gacgctttag aaaagctatg atttcggttg ctcgtaaaaa
     6181 tggcaaaaca attctgatag ctggtatctt gctttatgaa tttttgtttg ggcataatcc
     6241 atctatgagt agacaattgt tttgtacagc taatgaccgt acacaggcta aaattgcttg
     6301 ggacatggca aagaagcaac tctcatcttt aagagcaaag gacgctgatg tcagaaaagc
     6361 cacgaaaatt gttcgtgatg agctgaaaaa cttacatgat gaatcttata ttagggctct
     6421 tagtcgagat actggggcag tcgatgggtt cgagccttac gttggcgttt tagatgagtt
     6481 tgcggcatca aagacaaacg aaatgttaga gcttttagaa tccggtcaag gtcagcttga
     6541 taatccgttt atcttgatta tctcaacagc tggtatggat ttgaatgtcc ccatgcacac
     6601 aattgagtat ccgtacatca ctaaaatttt agacgaagaa attgtagatg atggctattt
     6661 tggatatgtc gcagagcaag acaacgaagg tgaaattaaa gatgaatcaa attggataaa
     6721 atcaaatcca atcctcgagg ttgaagcttt gcacgataag ctaatggatt acctgagaac
     6781 gcgtcgtaga gtgtctcttg aaacaggtga aattaacaag gtacttatca aaaactttaa
     6841 catgtggcgg cagtcgagtg aggaatcata tattgataag caatcttggg aacttgctcg
     6901 tattgataaa cccgacacac ataaacgaag ggtctggcta ggtgtggacg tcggtcgtgt
     6961 tagtgactta tttgctatta caccagttat tatgatggac gatttttggt atattgacag
     7021 tttttctttt gttgcgacaa agtatgggtt aacggctaaa gaaaagcgtg atggtgtgtc
     7081 ttacagtaat ttagaacgtc aaggctattg cgagataaca acattagaaa gtggggttat
     7141 tgatgatgag agagttttag aaaaaataga ggagatggtc tattcgaatg actgggaagt
     7201 taacggaatc tgttttgacc cttaccaatt tggaacgctg cttacgatga ttgagaaaag
     7261 gcacccagaa tggcctctca tagaggtttc gcaaacgaca atggttttga acatgccaac
     7321 aaagcaattt cgtgatgatc tcaagaatgg caaaataaag cactctggca atccattgct
     7381 aacaatggct gttaataacg cttatatcaa gactgataac aatggcatga ggattgataa
     7441 gaataagaat agcaataaga tagaccctct ggacgctgct ttagacgggt atgcagtttg
     7501 ttacttagag ccatttgacg gctctggtta ctggacaagt gagaaaattt taggaggaga
     7561 gacactgttt tgattggttt tattttaaaa aacatacata cattaatctt gttagctgga
     7621 ctaggtttat tgatgtatgg gttgtttttg tttggtgata aagttggttt tatcgctagt
     7681 ggtcttattt taattttttt agctatctat gtagatagcg taggaggaaa acatgaataa
     7741 acgcattaag aaaaaacgta aattggaaac agcggttgtg atgcttgttg cagaaaatgc
     7801 tatgcaagct gaagtactca ggaatcaaaa cagacaaatt gcagagctga gatcgattat
     7861 acaacaaaac gcccaagcga caaatagaga gtttgcagca gttaaatcag cgacgctaga
     7921 caaccaagca gccattaaga aaattgggga tgaggtttat tatatcaagc aaaattataa
     7981 gcgcaagtgg cggaaataga tgttaatggt ttagaaagga ggtgagaaat cgatgagttt
     8041 ttttcaacct ttgggcagtt caaaggtgtc ctatgatgac tatgtatcat ctgttttagc
     8101 tggcgatgtc tcccaaaaat acttaggagt gtcggctttg aagaatagcg atattttaac
     8161 agcaacgtct attatagctg gggatattgc taggtttccg cttgttaaaa aggatgttaa
     8221 tggggacatt atccatgatg aggatattaa ttatctttta aatgttaaat ccacaaaaaa
     8281 tgcgagcgct aggacctgga agtttgctat ggcagtaaat gccattttga ctggtaattc
     8341 tttttcgcgt attttgagag atccaaagac taaccaagct ttgcaattcc aattttacag
     8401 gccgtcagaa acgactgttg aggagacaga taaccacgag atagtttata cgtttactga
     8461 tatgttgaca gcaaaacagg ttaaatgttt tgcccatgac gttatccact ggaagttttt
     8521 tagtcacgat acaattttgg gaaggtcccc gctactgtct ttaggtgatg agattgattt
     8581 gcaaaccggc ggcatcaata ccttaattaa attcttcaaa gatggttttt ctagtggcat
     8641 cttaaaaatg aaaggcgctt atataagcgg tgaagcacgt aagagagcca gagttgaatt
     8701 tgaaaaaatg cgcgagggtg caattggtgg tagtccttta gtattcgacg atacgcaaga
     8761 atacacgccg cttgaaatcg atactaacgt attgcaatta attacaagta acaatttttc
     8821 aacggcgcaa atcgcaaaag ctttgcgggt tcccagctac aagcttggtg ttaatagtcc
     8881 aaatcaatct gttgcccagt tgatggaaga ttatgtcacg aatgatttgc cattttattt
     8941 tgatgctatc acaagtgagt taggacttaa gacgctaagt gataaggata ggcgtttgta
     9001 tcgtatcgag tttgatacac gaagcgtcac aggtcgcaat gttgatgaga ttgtcaaatt
     9061 ggttaataac caaatcttga cgcctaacca aggcctcgta gagcttggta agcaaaaatc
     9121 aacagatcca aacatggata ggtaccagtc tagtctaaac tacgtctttt tagacaaaaa
     9181 agaagaatat caagacaagg ttggtatcaa agggaaagga ggtgaggtaa atgccaaaga
     9241 ggataaatct taaaggacca ctaattgcaa ataactctca agaagtttac gactattacg
     9301 gaatggaagc agcaagtgct aaaagtatca ttgagcaatt tcctgaagat aatagcgata
     9361 ttgttttgga agttaattca aacggtggac ttgtgacagt tgggagtgaa atctataccg
     9421 ctttacgaaa ttacaaagga aaagtaactg cagaaattac tggcatggct gcaagtgcag
     9481 catctgtggc tgttatgggt gcggataagg ttgtcatgag tcctacagct caaatgatgg
     9541 tgcataaagc actctttaaa tgggtgtctg gtaatagtga tgacctagac aaagcttcta
     9601 atgccttaaa atcaagtgat aaagctattg tgagtgccta tgtcgcaaaa acagggttat
     9661 cagaagatgc aatcatggat ttaatgcgaa atgaaacgtt tatgtccgct caagatgccg
     9721 tagaaaaagg ttttgcggac gaagttatgt cttttgaagc agttgctagc attgataatt
     9781 ccatgttgcc gcaagctgtt attgatgact attacagaag taggaacaaa cgaaaacaag
     9841 agattagcaa catgttacta gaaattgaaa aagaagaaat tttacgaggg ctataagctc
     9901 tttttttatt ggaggaattt atgttcgaag aaaaaatcaa agaaattaaa gcgaatatcg
     9961 ctaatttaaa ccaagctatt gctactaaaa caacagaagt aaaaaatgct ttggaatcag
    10021 atgaccttga aactgctcgc tcaattaaag cagaaattga agaagctaaa gcaaacctag
    10081 cagaagcaga aaatgacttg aaattgtatg aagctagcgt tgaaaaaggc ggtgcagaaa
    10141 atactggagg aaaagaagtg ccacaagaaa ctaaaacata tcgcgaaagc gttaacgaat
    10201 ttattcgttc aaaaggaaca gtaaccaacg aaggtttgcg ttttgaaggg aaagacgagg
    10261 ttcttatccc acttaaccaa acaacgcctg tagaccctaa aacggatggt gttaagaaaa
    10321 cggatgtaaa acctgtctct agtgaagaaa ttctttacac accagcgcgt gaagtcaaga
    10381 cagttgttga tttgaaacaa ttcactagca tccacccagc taaaaaagaa tcagggaaat
    10441 ggccagtatt gcaacgtgct acagaaaaaa tggttagcgt tgaagaattg gaaaaaaatc
    10501 caaaactagg caaaccacaa tttaaaaacg ttgaatggga agttaagact tatcgtggag
    10561 ctatcccact gtctcaagaa tctatcgatg atgcagatgt agatttggtt ggtattgttg
    10621 ctgaaacaat cggtcaaatg aaagttaata caactaatga tgcaattgct aaagtcctaa
    10681 aaacatttga ggctaaagct ggtgtcaaaa cattagatga catcaaaaaa atcctaaatg
    10741 tagatttaga tccagcttac aatgtatcat ttattgtatc tcaaagtttc tatcaaaccc
    10801 tagatacttt aaaagacaaa aatggtcgct acttgcttca agactcaatc acctctgcgt
    10861 ctggcaaagt gttccttgga aaaccagtat ttgtcctatc tgatgacgtg attggcgaag
    10921 actcagcttt tgtcggagat tttaagcgag gcgtgttatt cgctgatcgt aaagatttag
    10981 ggcttcgttg ggcagataac gaaatttacg gtcaatactt gcaagctgtc cttcgctttg
    11041 gtgtcgctaa ggtagatgac aaagctggat actatgtgac attcaaacca gaacaattgc
    11101 cctcataagg ccactgaaga agtggcgaaa ccaactagca aaagcactgt cgaggagatt
    11161 aagcgctatt taacaagcaa gggaattgac tttaatggga aaacattaaa atctgattta
    11221 ttaaaacttg caggcgttga agaggtatag ctatggctgt atcaaaagag ttattagaca
    11281 gtgtaaaact ctattgtaaa attgactttg attttgatga cgacatcatc aaagaaatga
    11341 ttgaatctgc tcaagaacaa atctgttttg caatagaaga cggttctact cctgaaaagt
    11401 tcaaaggtca cgctaaattt aatttagctg tcaaaaagca agtcaaggaa gagtatgacc
    11461 atcgcggttt gtctgcggat agttttcgct atccgttggc aaatggtgtt ttaaacatta
    11521 tccatcaatt gcgattgaga ggtgatgatt cgtgattaca cgcaagatga acgtcaggat
    11581 aacgattttt agccaatcag gcgggcaaaa tgaagatggt gaagtagtat ctgctgtcag
    11641 aaaggacttg tatacttgtt gggcagaagt gctaaaaacg cagttgagag attttaatta
    11701 tcaatcaaag tatcaaaacg ctagcaattt gccaacaaat aaggatacta aggttttttt
    11761 aattaggtat aaccctgaat tatctataga taacacgatg tttgttgagt ttggcaagcg
    11821 catttataag atagataaaa tcgaatctga cgaatctggc aaagatatta tcatgataag
    11881 tggagtaagc atgtcatgac aaaaggttta gatgaaatat tggctaatct gacaaagctt
    11941 gaagtaaaag caccaaaaac cgcaaaagca gcagtaactg aagttgccaa agaatttgaa
    12001 aaagcactta aagcaaatac ccctgtttat gagattgaaa cagatgagcg gctacaggaa
    12061 gataccgtta tcagtggttt taaaggagct aatgttggaa ttgtatccaa ggaaatcggc
    12121 tatggcaaag cgactggttg gcgtgcgcac tatcctaacg atgggaccat ttaccaacgc
    12181 ggacaagact ttaaggaaaa aactatcaat cagatgacac caaaagctaa acaaatctac
    12241 gcagcaaaag ttaaggaggg actagggctt tgattgctga aacagcagct tataaattat
    12301 taagtaacga taagacgcta aatgagttgt tggataggct cagaggcggt ccttttaaaa
    12361 atgggtttaa gcaaggcata tttacttatg atattccaga taacccagtt gacttgcgta
    12421 aggtagattt agcgcctttt atgcgaatca acacaacatt agacggtcct gctgattatg
    12481 cagatgatga gatactgtgt aacgagcaac ggatcaccat caatttttgg tgcaaaacag
    12541 cttctgaagc tgaccaaatt agcaaatgta tagatgatat tttaaaaaaa ggcggttttg
    12601 aaagatacac cgcaaacgaa aaaccaagat ataaagatag cgatattgac ttactcatga
    12661 acgtaaggaa ataccgctat tttgattttt atttaaaaga aagaggaaaa aatgggaaaa
    12721 gtaaaatttg gactacgtga ttttcagtac gccgtactag gcgaagatga taatgttgca
    12781 acgaaaaaag gtggtattaa aaaactacct ggaatgaaat ctgcaaaact cgatattacc
    12841 aatgaattgg ttaccgtttc ggcagatgat gggccttatg tagtgctttc gggaggaatc
    12901 accgaaacaa aactagaaat tgaagtactc gatcttacaa ccgatgcacg taaggacttt
    12961 ttcggcatta aagtggcggc aggtgttgaa aaatataaca aaaacttgac acctaataat
    13021 gtagcctgca tttttagaac aagtgatgag aacgggaagg ctatttgggt aggactgctt
    13081 aaaggtaaat ttaatttacc tggcatggaa actcaaacaa aagaaggatc tcctaacccc
    13141 aaagctgata ccgtaacagg taactttgtg tctcgtggca ccgatggaga cgtgcttgtt
    13201 attggaagag aagaaagtca tgaatttaat tatgaagctt ttgcaggatt tgtttttgct
    13261 ggtgcgacag atattaaaaa aggcgaaaac ttcgaaatgt aacaatcagg ttggatttta
    13321 aatccaacct tttatttttg ataaggagta gatatgtacg aaattacctt aaaaaaaggt
    13381 ggtgtagata aagttttttc aaaagacttt attaacgttg aggataattt gttggctgtt
    13441 gagcatcaag ttagacaaag cgctgtgttt agcgatgaga aaagacgctt agattctaaa
    13501 gcgcatagaa aacttaacga atcttacttg caaatgtttg ttgatatgta cgcaggtcaa
    13561 tttacagtcg atgatttaaa gcaatctgac atgagtgttt taaatacact taatgacctg
    13621 tacattgcag cactcggtgg agagcaagag gaagacgaaa gcgaaaaaaa ggaacaataa
    13681 ccccacaaga ggctaaagaa aacttactct tgtggataca gagccttttg aaaaacggtt
    13741 ataccatttt agatattaaa aaaatgcgct tatctgatat tgaattgatg gtacaagcgc
    13801 tagaaattga aactgtcgaa aaagaagaag tgattgaaac gaccttggat aaggcattcc
    13861 cattcctttt cggctagaaa ggaggctaaa tggggaatat aggtgattta gtagcaacgg
    13921 ctacactaga catatcacca tttatgtcaa acacaagaaa cctaaaaacc tacatgaaag
    13981 gcttagacaa ctcgttaaaa gctgttgaaa agagttttca agggcatggc gggcggatta
    14041 aaggtcttaa agcggtctat gctgaaacag gtagtgcatt aaaaggttac caagaattac
    14101 taaaaactca gtcacaaaaa tatagcgacc taaaaaaaga gataggcgat gttaataacg
    14161 ctactgctga gcaaaagcaa aaattgattg gcgctaaatc agccatgttg gagactgctg
    14221 cgaaagtcac agaattgcaa aacagattac gagcgttagc cactgaaact agcgttttta
    14281 caagatttgg taaagctgct gaaaaaatcg gcggcaagat gaaatcatta ggtgattctg
    14341 tagcaggagt tggtgctgca tttacgagag gagttaccgc tcctattgta gcgggcgctg
    14401 gttatgctat taaagcagct gttgactatg aaactgcgtt tgccggtgtt aaaaaaacag
    14461 ttgatgagac ggcgacagta tcctatgcta agttgtcgca aggcattagg caaatggcta
    14521 aagagttgcc agccagcgcg gtagaaatcg ctcacgttgc agaggcggca ggtcaattag
    14581 ggattaaaac aggtgatatc cttagttttt ctcgtacaat gattgattta ggagaatcca
    14641 ctaatctatc cgcagaagaa gctgcatcat ctattgcgaa aatcgcaaac attacaggac
    14701 taacgtcaaa ggaatattct agatttggta gctctgttgt tgccttaggt aataactttg
    14761 cgacaactga aagagatatt gttgcgatga caaaccgtat cgccgcatct ggtaaacttg
    14821 ccggcttaac taatcaagaa atgttagcgt tggcaactgc tatgtcaagc gtcggtatcg
    14881 aggcagaagc tggtggtact gctatgactc aaacattatc agcaattgaa actgctgtta
    14941 ttaatggtgg agaagattta acaaaatttg ctcaaattgc caatatgtca tccgctgatt
    15001 ttgcaagagc gtggaaagag aagccaattg ttgcattgca agagtttatt aaggggcttg
    15061 gtcaacttga taaaaaaggt gaaagtgcta caaaagtgct tgatgaactc ggtttaagtg
    15121 gtatccgcca gtctaacatg ttgaaatctt taggattagc atctgagact ttaggcaagg
    15181 ctcttggaat ctctaacaaa gcttggcaag aaaacactgc tttaactgac gaagctaata
    15241 agcgctatga gacaacagag tctaagctaa aaatgcttaa gaatgaagtt aatgatgtag
    15301 ctattgaatt tggtggccct ttggttgacg ctctaagaaa tgggctcgaa gcaggaaaac
    15361 caattattca aatggcagca gatttagcca agcaatttaa ctcgcttgac aaagagcaac
    15421 aacagcagat tatcaagtgg ggacttattg ctgccgccgc tggtccagct ttgtctatct
    15481 ttggtaaagg tgttggcatt attggcagta ctattcaagg cattgggaaa atgagtcaag
    15541 gtttaggagc gttgtcaggc tggttgcgca cttttaaaac tggagcggca gcagctagtg
    15601 caggagccga agctgccaca gcttctatgg gcggaatggc tggcgcggtt gccttattaa
    15661 gcaacccagt aacgtggggt gttttgctag gtggggcagc cattgtgggt ataggtttaa
    15721 ttgctgatag catgtataaa gcccaaaaac gcacagaaga gtggggaacc gctgtttccg
    15781 cgacagaagc aaatgcacta agtaacttta agaaaaaagt tgacgaaact aacacttcgt
    15841 tgcaaatgtt cgaggcaggc gcaggtagcg ttaagaaagt gactgaagct tttgatgatt
    15901 tggtcggaag tattgaaaag ttagctcaat caaaattaga taagaatata aacttagcta
    15961 aaaaattagg attatcagaa gaaaccataa atgctttgaa atccaaaact gaatcagtgg
    16021 ttaacaatgt taaaagcatg aatacccaga ttaaagcaat catggagaaa cacaacggtg
    16081 acatgagcca gttgtcaagc gctgaaaaag aacttgtttt gcgaaatcaa agagaaatga
    16141 ttaccgctca acttgattta atgaagttct ctgcatcaga aaagaaagct ttaacagcag
    16201 ctttgaataa cgaattagat gccctcaacg caagacagtt ggaaaaagta tccgaaaaca
    16261 ccgttaagat gcttgataaa gaaaattctg cttacaaaac aaaaaaagca gaattaaaag
    16321 aaattttaaa gcaatttgga agcgatacta gcaagctaag cgctgaagaa ttggctgcta
    16381 gacaggaagt tttgaataga cttactgagt taaatatgca gcacaaccta aaaaccaaag
    16441 ctttgaacga tcagtacctt gctatccaga gggagcgtgt ccaacggtta aaagaatctg
    16501 gcaagagtca agaagaaatc caccaaggga ttagccaaat ggcatcagac atggctcaga
    16561 agcttggtat tagctatgac gatgcttacc gtaaactagc ttattatact gagaaatctg
    16621 gtgaaacgtt gaaagttttg tcgcgtaata cggctaatgc tacggcggaa gtagcagcag
    16681 ctaacgctca gtgggatagc ttgtttacga gcgataatcc acaacaaagc ctaaacgaat
    16741 tgttatcgac cgcagaaggc tggaacagtt ttgaaatcat ggttaagaat gccgacgttg
    16801 aaccgacagg tagagccgca cttgctgaaa tgttggtagc tggtggccaa tgggaaaaca
    16861 tgacgttaga gcagaagaag ttggttgttg atggtcaaca agcgatgatt gaaatctttg
    16921 atagcaagga gttattagcg cagtggcaag cattgacgcc agaagaaaag gttttgctag
    16981 cgaaaaactt aacacaagaa ccaactatgt cggctcaaca agcccttgac agtgtcaagc
    17041 aaacagtacc tgctgatgtt aacgcaagtg ataaaacagc aggcgaaact caatcagcac
    17101 aaaacaagat tgacaatgtt aaacaacgag ttccagctga tgtgaaagca tcggataaga
    17161 ctggaccaga tgtagcaagt gctgacaggg ctgtcaatag tcctaaacaa aaaagtccag
    17221 ctgttatcag agcccaagat aatgctagcg gtgttgcaga aggtgttata ggtgcattgg
    17281 ctagaatccc aagaagtgtt acaacaacca ttacaacgtt tgtccgtaag atttttggac
    17341 atgaaaaagg gactgatttc caccccggcg ggttagctat ggtcaatgac caaaaagggc
    17401 cgctatacaa ggagttggtc actttaccaa cgggtgaatc atttattcca agcggacgaa
    17461 atgtcatcct ccctttgcca agggggtcta aagtcttaaa ggccagccgt acaaaacaat
    17521 tattcccgca ctatgccagc ggaataggtt ttgatgacac caaaatcgct agtctgacaa
    17581 ctcgtcttaa atctgtgcaa gataaggggc aagtgattat caataccgac cctcaacttg
    17641 cggagttaat taaactactt aaagacagag atgacagaaa tgtcacaaat aactataccg
    17701 taaacgctac taatagtagt agttcagagg atatgtttag ccaagaaaat atgagacggc
    17761 tactcagaga attagcttac tacacgaacg gagaaggagg gaggttagct taatgcgata
    17821 cattgaattt aatggcacta aaagcaatga tttaggttta ttgctagagc gcgaacgatc
    17881 aattaagtca acaaacaacg acattgattt aatcgaagta gcaggtcgtg acggtgtact
    17941 tattaaagac aacgaacgct taaaagcggt tgagcaagac tttccttttt cgctggttgg
    18001 tgacgtgact gtcaatcaac aaaaaataag cgaatggtta catgtcaagg gttggcacga
    18061 cttggcgttg tcttgggaca aggattatat ctatcgggct agtgttgtca atctttttga
    18121 aatagacgag atacttaagc aatttggtag attaaaagtt aatttcttaa tccaccctat
    18181 caaatattta aaaacaggta agcaagaggt gcctctcgta aatggaggta ctctacaaaa
    18241 tcctggcaat gtccaagcta aacctatctt aaaaatcaaa ggcacaggca atggtgtttt
    18301 aaccattaat gactttgaga caggacttga aaatgtacag ggcgagcttg ttatagatat
    18361 ggaaaggcat cttgtctata aggatgtttt atcggcttgg gataatatcg taaggacaga
    18421 acatcatcgc atgcctcttt ttgatattgg tcaaaacaaa atctcatgga ctggtaactt
    18481 tactatcacc gcagtgccaa actggggggt taaagtatga taccagtttt atacgaggcc
    18541 aaagaaacca aatttaggac ttttggcctt ggagaaattg cggacgctta cgaggttaaa
    18601 gctacacgtg agcgtaatgg caattactcg ttatatatca aatatccttt agatggtgcc
    18661 tttgctcatc tgttcaaaga agagatgaag attaagtccg atgctgggcg taggactaag
    18721 tggcagacgt ttgagattaa tcgggtgctg cggaatagta aagagcacat tgagattttt
    18781 gcacgccaca tatcgatgcg cacacaggac atcgctttaa aaccatttgt gagcgggtct
    18841 agcattgacg cagagtcggc actggaggtt tggcgggata atcttgtcgg tgatgatacc
    18901 tttgatgtta aaagcgacat tttaacacta ggcagcttta actgggaagt tgacaagata
    18961 ggcaatgcaa gaggcgctct cgggggtgtc gctggctcta tcttagatgt ttacggtggt
    19021 gagtacgagt ttgacaatcg cacaatcatc ttacataaac aaatggggcg taagacccct
    19081 acggttttgg agtatggccg caatatcgtt agcgtggaag aggagcgttt gcttgatggc
    19141 aattatacct caatctatcc ttacgtaaga tatacgccac aaccaaagcc gcaagaggaa
    19201 gcctctggta agccgcacat cggcgagcat gagaaacccg aagaacagct ggtcactttg
    19261 cctgaattta tcatagacgg tcagtatctt gacttatatg cccaacgcag aatacagatg
    19321 gttgatttat ctagtcattt taatgatgac aaaaaagagc caacagtcga agaaattaga
    19381 aagctggctc agaaatacct taaagataat aatgtaggcg cacctaaaat cagtatagag
    19441 gttgattata tcgacctgtc acagacgctt gactatcaag attttagagt tatggaggag
    19501 gtcgagcttt gcgatattgt accgctttac tatccaaagt ttggtatcac aaccgagacc
    19561 gaaaaagtcg ttgagattgt ctatgacgtc tatacagata gcaatcacac aataaagctt
    19621 ggcacgattg gccaatccat ctctaagagt ctgacaggtg gtgttacgca gcggattgag
    19681 acgctggaaa acaaccaaaa ggttattact aataatcaac agcaatttga gcttaattta
    19741 cccaaatacc tcaacgatct aaacggtacc aagatatggt acgaaaaacc agatgacaac
    19801 gttgagcaca agataggcga tttttggttt gagaaaaacg gtaaatatca gcgtacctgg
    19861 gtttgggacg ggaatcaatg ggtaaaaatc attgatactg aggatttaaa tcctaatcag
    19921 cgcgcttttg atgaggctat ggccgagatc gaaaagctta agcagcacca acaacaaatt
    19981 gacaaacgca atcagcggga gcttgaagag tttagagaca ccctcaaaaa cctagcgtta
    20041 ccagaggaag cgatcaaaaa aatcactgag gctatcaaag ttgatgacat cccgtcaatt
    20101 aaacagtcgt ttgatgactt aaaaaataaa gtcagcgaga caagcgaaac cgcacgatta
    20161 aacgctgaga ttatcgggac agatggtaag acccgctata acaaaaatct cttggttggc
    20221 gaccc
//
LOCUS       DARYXW010000033        20022 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.033, whole genome shotgun sequence.
ACCESSION   DARYXW010000033 DARYXW010000000
VERSION     DARYXW010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20022)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20022)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20022
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.033"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            <1..1230
                     /locus_tag="TV191_000966"
     CDS             <1..1230
                     /locus_tag="TV191_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEL1507494.1"
                     /translation="FNKHIYDKLYDYDTFTEVHYGGASSGKSHGVIQKVVLKACQDWK
                     HPRKVLFLRKVGATVYDSIFEDVKQCLELWGLLDKCKVNNSAYRIELPNGATFIFKGL
                     DNPEKIKSIKGVSDVVMEEASEFTLDDYTQLTLRLRDRKHLKKQIFLMFNPVSKVNWV
                     YKAFFVKTPKNTVVYQTTYKDNRFLDDVTRENIEELANRNEAYYKIYALGQFATLDKL
                     IFPKYEKKILNKDKLSHLPSFFGLDYGFINDPSAFLHVKIDDNNKKLYILEEYVRKNL
                     TNDKIANAIKDLGYAKEEIRGDSAEKKSNQELRNLGIPRIIDVKKGPGSVMQGIQYLL
                     QYDWIVDERCVKTIEELENYTWKKDKKTNEYINDPVDSYNHCIDAIRYATSNHFLTLD
                     KKQSNSFNIFRKAGFGL"
     gene            1242..2744
                     /locus_tag="TV191_000967"
     CDS             1242..2744
                     /locus_tag="TV191_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000930109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL1507495.1"
                     /translation="MLYTETFKDSTGNAKLLEFRFHRESRMRYQTSDLSGLFDEGYKL
                     LLDYIKHHESKQKPRIQELLDYAEGNNHTVCESGRRREADMADSRAIHNYGKYISTFK
                     QGYLVGNPIRVEYEDNDDAKKQLFKELADKNNFHQLNRRLVKDLSKVGRAYELIYRSM
                     DDKTEVVRLDPRETFIIYQADVGQASLVGVRYYNKSQLDRTKKTVEVYTDNEIIYFDY
                     DGQLTEVDRRPHIFKSVPITEYLNTDDGLGDYETELSLIDLYDAAQSDTANYMQDLSD
                     AILAIIGRVSFPSYVDTKEKAIEYLRAMRKARLLNLEPPVDTEGREGSVDAKYLYKQY
                     DVNGTEAYKDRVVQDIHRFTNTPDMSDSKFAGTQSGEALKWKVFGLDQERVDLQALFE
                     QSLKRRYKLIARVSELLKEIDGFDISKLKITFTPNLPKSLHEKIEAFKALGGELSQKT
                     TMSITDIVENPDKEIASINDEAKNRSLLAQKMESEGRMTDRELARDYNHE"
     gene            2725..4302
                     /locus_tag="TV191_000968"
     CDS             2725..4302
                     /locus_tag="TV191_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HEL1507496.1"
                     /translation="MTTIMNKSKYWRDRVKKEMDAKEADDISLEQSMKQLHNYHFRNI
                     EKEIESFYQRYADKEKIDIAEARKRVSELDISAYQKKAKELVVKAEKLRKEGKTVTRD
                     DFTHQENADMAIYNLAMKTNALELLRLNIDLEMQELANGEHKLTKTFLDEGYRKEVEF
                     QAGLLGLSVASQASVKGLADAVINANFKGAKWSDSIWDRQDKLRSIISQSVQSAILKG
                     KNGLTIARDIRREFDVSVSYAKRIAITEHARVQMEVSRLSMAENGFAMFDIIPEPKAC
                     DVCKDIAKQGPYHMDKWRTGENTPPIHPYCRCAVVGVEEENSSNHESLDKLIKTEYNQ
                     SMKESSTYARNVLSAVSLIEPRITSQIKHIVKQSNGNLQGLDFRLKSLDSLARKISTD
                     SLLDDISPEEAANNINDALRYTAVFKPDNFFDDYHSMKNALVRDGFKIEKVKNTWLDD
                     GPYNGVNTVVSKDNVKFEIQYHTQESFDLKNGKLHELYEERRLPNITRKRKAELDKMM
                     FELSKSLTKPNQIERVN"
     gene            4304..4510
                     /locus_tag="TV191_000969"
     CDS             4304..4510
                     /locus_tag="TV191_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507497.1"
                     /translation="MITKYFFIKTEHPKIVRYSNGLTEVYNSAKGWEEQEAWYDRLFF
                     SDFSDFEEVTEKEAKMFIAGLTAA"
     gene            4507..4926
                     /locus_tag="TV191_000970"
     CDS             4507..4926
                     /locus_tag="TV191_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEL1507498.1"
                     /translation="MSIVELAFRVAKKAHLGQVDKAGVDYIKHPITVASFVKTDEEKA
                     TAYLHDVIEDTSLTLLDLEEYDFPRSVIEAVDILTKKKGQDYQSYLNLVKTNKLARTV
                     KLADLKHNSDLSRLSEVTNKDLKRYKKYQEAIKYLNN"
     gene            5123..5392
                     /locus_tag="TV191_000971"
     CDS             5123..5392
                     /locus_tag="TV191_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507499.1"
                     /translation="MNKRIKKKRKLETVVVMLVAENALQAEALINQNKEIMELKSIVE
                     RNALATNEELATVKDTVLDNQSVIKAIGDTVDYIKQNYKRKWGKK"
     gene            5428..5595
                     /locus_tag="TV191_000972"
     CDS             5428..5595
                     /locus_tag="TV191_000972"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507500.1"
                     /translation="MKVKEIAQVFNEYSDFFVVQNGKYLPGDRTSFFLDCELEIKEIS
                     IGIPDCLIIEV"
     gene            5777..6400
                     /locus_tag="TV191_000973"
     CDS             5777..6400
                     /locus_tag="TV191_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEL1507501.1"
                     /translation="MNKKLLEKLFKCAPDTGTGSGGASDADSQQSETDGEPSSEDSFK
                     APQSQSELDSYTNKAIQKALENQRKDEAKRIEEAVKAALDKEKDYSKLSEEERQQREF
                     EDSKKAFEAEKAKFEHDKLVVQVEKDLIAKGLPSEFAELLATKDAENALEQVKTFEAA
                     FKKAVADEVKKTVRQLTPSTGAGAISTQTNYGANLASKIAQQSTTLF"
     gene            6411..6791
                     /locus_tag="TV191_000974"
     CDS             6411..6791
                     /locus_tag="TV191_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head decoration protein"
                     /protein_id="HEL1507502.1"
                     /translation="MNKRKVTTSKEILHNLEYEAITVTLDSSTVGKKVIPAGTVLAGV
                     SDSVFKDRKQKVKTVANHEVSGESNICGILLTDVDLTDGDKAGACVYRGTVNADKLAD
                     SSIAENFTELATKLPHVVFIKGGK"
     gene            6794..7843
                     /locus_tag="TV191_000975"
     CDS             6794..7843
                     /locus_tag="TV191_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major capsid protein"
                     /protein_id="HEL1507503.1"
                     /translation="MALIHEIITSENIKGFYNAKNENIDKTLGEKAFPPKQQLGLKLS
                     FIKGAAGKPVTLKAAAFDTKVPLRDRMAVELLDEEMPYFKEAMLVKEADRQELNIISQ
                     TKNSDLIDTVLAAIYNDKVTLIAGAKARLEAMRMEVLSKGKIHVASNGVMKDFDYGLD
                     SSQTTKPSVKWSEAETATPLKDIEGAIEKMAERGFVPEAIIMNSKTFSLIKNAKSTLK
                     IIKPMAPDGAAVTKGDLTTYIADELGLKILFKDGMFIGDDGKSRKYFPDGFATLVPNG
                     NLGYTVFGTTPEQSDLMGGHATDADVSLVETGIAITTTKTTDPVNVQTKVSMIALPSF
                     ERLEEVQIIDSIDQV"
     gene            7854..8120
                     /locus_tag="TV191_000976"
     CDS             7854..8120
                     /locus_tag="TV191_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507504.1"
                     /translation="MAEVIKTFRDKETTNTYYVGDDYNGDRIDELTAKGYLSGDKVSA
                     AAIEIDLDKLKVDEIRAKLDELGVAHDPKLKKPELLELLKQSAS"
     gene            8130..8483
                     /locus_tag="TV191_000977"
     CDS             8130..8483
                     /locus_tag="TV191_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEL1507505.1"
                     /translation="MQKINTDSIIANVKLDLGIDDTLQDSLLNMLLKRVTDHFKAEYG
                     VDDIDNAFSFVLEDCLIARFNRRGSERAKSEEVEGHKTTYYDFLNEFEPYDKMIKSNL
                     NLIKDNSRKGGLYFL"
     gene            8480..8788
                     /locus_tag="TV191_000978"
     CDS             8480..8788
                     /locus_tag="TV191_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507506.1"
                     /translation="MRYADRITFVKATDEQYDPDLGEYTYTEVMIKTLPCFVMDLGMA
                     KSVQIFGDYQKTRKVVYLRQPYTDLLDHCLYKGKKYKVQVDKQFNTVFYLEGDDSICS
                     "
     gene            8769..9134
                     /locus_tag="TV191_000979"
     CDS             8769..9134
                     /locus_tag="TV191_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEL1507507.1"
                     /translation="MILFVADISLKVVGTTGLKNKLELIAKKEAVKKIVRDNGKQLHR
                     KMVQKAVFTKGHSTGATRISITMQIGDDGFSVTVKPGTHYAGYLEKGTRFMSKQPFVL
                     PALKEQKVKFRKDLEALVK"
     gene            9131..9520
                     /locus_tag="TV191_000980"
     CDS             9131..9520
                     /locus_tag="TV191_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HEL1507508.1"
                     /translation="MIKTRDQSIFDEMFKRIQSLGFKVYDYKPMTEVPYPFVEMESTD
                     AEYIPNKDDIKGSVDLVLSVWGLQKKRKQVSDMASAIFSQAMSVASSDSFYWSLNIRQ
                     SSIQVLDDTTTVTPLKRAIVTLRFNLR"
     gene            9530..10121
                     /locus_tag="TV191_000981"
                     /pseudo
     CDS             9530..10121
                     /locus_tag="TV191_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052382.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
     gene            10183..10542
                     /locus_tag="TV191_000982"
     CDS             10183..10542
                     /locus_tag="TV191_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly chaperone"
                     /protein_id="HEL1507509.1"
                     /translation="MQLEIKGKTHNIKFGTRFVAEMDKNHIAEREGMKFGAGLQSTVP
                     FLFERNVVTLAEIIYTGTITESPRPSLNDIYDYIDEAEDIEKLFDDVLDELRQSNASK
                     LFITKLDKNIAEMATEA"
     gene            10584..10913
                     /locus_tag="TV191_000983"
     CDS             10584..10913
                     /locus_tag="TV191_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507510.1"
                     /translation="MIVLNCVRYLGMTDINEIGRLTLYEYDLLMIGKALASVDEAYKA
                     HKQAWINHQVSATRLVGGGKNKREVPVYKTFKEFFDYETEIKKITNEIDESYDKKAMD
                     LLLKANL"
     gene            10930..14184
                     /locus_tag="TV191_000984"
     CDS             10930..14184
                     /locus_tag="TV191_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEL1507511.1"
                     /translation="MGESYSVEAVLTAVDKTFGKTLKSAVQSIEGLEKRSKGFSAVSQ
                     KAGSMFKSMLGANLAGQAITALGRTVSSGLISMIGEMNSSAKAWKTFDANLADIGFGK
                     QQILEAKTAMQDYATKTIYSASDMASTYAQLAAVGVKDTGKLVKAFGGLAASAENPKQ
                     AMKSISQQMTQAVGRPTVAWQDFRIMLEQAPAGMAKVAKAMGKNLNELVADIQAGRVK
                     TKDFLEAVKQAGNDKSFQKMATEFKTVDQAIDGMREGLSNKLQPAFEKVNQFGIRAIE
                     AIGKQLDKINFSKFAAGLGKFLEGVNIDSIISRISTSISSIVSKIKGFWDGFNQTGAI
                     SAFSGALQSVWGALKNTAKAMSGGSWKTFGSIIGEIVKHVSNFARVIGDVVGKMDPSR
                     LKSWIATLAAVGGGLKIFEKLTGQSVIGSFLDKIGSKFKIFGNKAKEGTEQAFNGVKR
                     SGGIISKIFNGLGNIVKSAGTAIATAAKGIATGFSIAFKGLGSAISMVPPATWLALGA
                     AILAVGAAFALAGTQADGISQIFKTVGDVVVQVLQQVTNSLATLIPIIVSAIGSILPI
                     VAGAISQVVAAVAGGLSQIITAVANGVSTIIGAFTGLLGGVSSVITSISGVIQSLAGV
                     ITSVFNGIATIISSVGSAIKDVLTGLGSAFKGFGNGVKSALEGVGTVIKSFGSAVRNV
                     LDGVAHIFDSMGNAALNAGRGVKEMAKGIKMLVDLSLADLVATLGAVATGLGNMAGSA
                     GQMTTLSSAMSEVANGMARLGTSATIAITGLTVFATTITTIQTAIATLPTILTAAASG
                     FREIGDSATAAVGRIQTFAAGTTVVASAFASMQSMIRSAMAAIVSSIITSFNQAASQI
                     QSILSRVLSQARTFGSQLEQQMRQSGQRSGQNLAQGLSSQQGAVINAVSSMVNAAVSR
                     ANAGASPMRQAGAYIGQGLAQGMYSALGAVTAAANALVAQAERAARAKAMIHSPSRLF
                     AKRVGQYIPQGVAMGIYKNADVVDDSVGELFDSINSFDFNIADRLTSIGARFQGVVKS
                     ESSQSLSQQQEFVHTAQPAYVNFSLGGNEYEAFVSDITNRQAKIEKIRLKRSSW"
     gene            14216..14995
                     /locus_tag="TV191_000985"
     CDS             14216..14995
                     /locus_tag="TV191_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEL1507512.1"
                     /translation="MYEFNDTIRGTPKVTFNLKTTIGEKVLEEELNNDLGTFRTLTVS
                     GRDMVDLEHQTTSVLGRDGEYFHNATVEVRKLEIKAKITGKDNRSMRLQYEKLNRLIV
                     SHNQVFLSFSDEPDRNYLGIFKSKDIPEEVSNEQIIGLVFICYDPFKMSDIKTKKGNT
                     VQNDGLFNTKPIITLNLSSSTKEIRLLHVESQKYIRLTGTYTTDEIKIDMTTGKITQN
                     GRNILSDLDMVNSRYFDLLPGKNTLQCDNATITADFREVYL"
     gene            14992..17049
                     /locus_tag="TV191_000986"
     CDS             14992..17049
                     /locus_tag="TV191_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1507513.1"
                     /translation="MIYLFDKLEQLVATVGTDDLLSWHFKVKNNDWDQASFEVPVDYD
                     IEPFVYFGFFNYDPSQKEDVFKLFKVIDYNLEDSKYYKGLDKAESDLDTIAIIKDKRF
                     RQSSADACIDGALEGTGYQVGKVEGISEIRTLSYYYISPRAAMIKMIEAFNCEFNVRY
                     TFVNNKITSRYIDLKKRFGKPTGKQFEHGNNLLKVVYEESTDDIVTCLIGRGKGEEIQ
                     YDEPEAKEVEGHLPEAEKRQGYGRRIEFSDVVWSVEKGDSIDKPAGQNFVALDSAREE
                     YGLSQNGELKHRWGVFVNEEIEDKAELLKATWDQLQRLSIPIRIYKAEILDIGPETWK
                     GDSVAIIYDEVKIAFETRVDEIDIDKLNFNRSVVTLGDYSVVQNREARSRKEAVQNMI
                     NDSIENITGLGMNLQEFFQGIEEKIATGKKEMEDNWRKVNLEFDNFKKLIEQEGRNFR
                     ERLEAETKELDERNQKELDEFRETLKNLSLPEEAIKKITEAIKVDDIPSLKQSFDELK
                     NEVSKNSEKSRLNAEIIGTNGKTRYNKNLLVGEPNRTKTYDQDFVEIEANDGGFRRGE
                     TYTISFSQTCELLKKVAITLTQPHNKGLKLVLTPTKAKMEAQTFDLTKDIEVISVYPL
                     SYRAVLTGDWYKSKQMDFNAAEVQDLALEMSYRDVVDSNNASLILDWSSNPDVIFDGN
                     GGS"
     gene            17049..17756
                     /locus_tag="TV191_000987"
     CDS             17049..17756
                     /locus_tag="TV191_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL1507514.1"
                     /translation="MSETISAIVVHKSMTKNEWESSDIILPQGQLVYESDTGHSKFGD
                     GKNRYADLIYQGGPPGAQGPQGPAGETGPQGPPGPTGQRGETGPQGPPGPQGPPGADG
                     KMTFEQLTPEQKQQLKGAGIQSISLDYEGYLTIQLDNGQSFRSDISLKGPQGEPGING
                     MDGPRGATGPQGPAGDPASIPDDVVRRGELAAYLLKSEYKAKGAGSGLSYKVVTQSEY
                     DDLYDYSDNELILVTEG"
     gene            17758..18372
                     /locus_tag="TV191_000988"
     CDS             17758..18372
                     /locus_tag="TV191_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507515.1"
                     /translation="MAYKLYTKADVGDNMLLVVGHLPDNTKRLKIQRETLDVLSITHY
                     SSYDMVQLKSTVKRSHSKNTVVTLVAAAASKPKAKPKHVLNFAKANKVYLGSTRVIAV
                     YLGDRLLWSDKDSSGNKTVSVVGSLDIRQSQKMLYLYLIASDIADVKSKRIKSIAING
                     VNLSSAAQINFEDSDYYCLVTIERVANIKEIKNIAQKNKITLEF"
     gene            18383..>20022
                     /locus_tag="TV191_000989"
     CDS             18383..>20022
                     /locus_tag="TV191_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HEL1507516.1"
                     /translation="MSRDPTIVIDETNLVIGTDGRMHYTFTASQDNQKVRLKSNCLGT
                     AHFNQLMIERGDQATDYVAPVVVEGTGQATGVFKSLEEMLSGLKSIKLELTDTKNSNL
                     WSKIKLTTNGLLREYHHDHISTEIVETAAGIAKRIVDDTGQKLALINETIKGVKREYQ
                     DADRQLSASYQASIDGLKAQLANDKIGLQAEIKLSAQGLSQKYDDELRKLSAKITTTS
                     SGTTEAYENKLEGLRAEFTRSNQGMRTELESQISGLKAVQQSTAKQISQEIKDRAGAV
                     SRVQQDLDSYQRRLQDAEDNYSSLTQTVKGLQSTVSDPKGKIQSRFTQLQGQIEHRVT
                     RDGVMSIINESGDSIKLAIQKAGGIDAKMSAKEIISAINLNGYGVRISGERIALDGNT
                     TVNGAFGAKLGEFIKLKADQIIGGSIDAAKIRVINLNASSIVGLDANFIRAKIEHTIT
                     SLLEGKVIRARNGAMMIDLLNSKIDFNSNATINFNNKDNALVRKDGTHTAFVHFSNAT
                     PKNYTGSALYASIGITSSGDGINSASSGRFCGARFFRYA"
BASE COUNT         6745 a         3508 c         4504 g         5265 t
ORIGIN      
        1 tttaataagc atatttatga taaattatat gactatgaca cttttacaga ggtccattac
       61 ggcggagcat cgtctggtaa atctcatgga gttattcaaa aagtagtatt aaaagcatgc
      121 caagactgga agcaccctag aaaggtgctt tttttacgca aagttggtgc aactgtttat
      181 gactcaatat tcgaagatgt gaaacagtgt cttgagttat ggggtctact agacaagtgt
      241 aaggttaata attcagcata taggattgag ctgccaaatg gggcgacatt tatttttaaa
      301 ggcctagaca accctgagaa aatcaagtca attaaaggcg tgtcagatgt cgttatggaa
      361 gaggctagcg agtttacgct tgatgattat actcagctaa ctcttcgtct gcgtgatcgt
      421 aaacatttaa agaaacaaat ttttttaatg tttaacccgg tatcaaaagt aaactgggtt
      481 tataaagcct tcttcgttaa gacacctaag aatacagttg tctatcaaac aacttataaa
      541 gacaaccgtt tcttagatga tgtcacgaga gaaaatatcg aggaactagc caataggaat
      601 gaagcttatt acaaaatata tgcccttggc cagtttgcga cattagataa gcttatcttc
      661 ccaaaatacg aaaagaaaat attaaataaa gacaaattat cacacttgcc ttcttttttt
      721 ggcttggact atggatttat taatgatcca tcggcatttt tgcatgtcaa aattgatgat
      781 aacaataaaa aactttacat cttagaggag tatgtgagaa aaaatctaac aaatgataag
      841 atagcaaatg ctataaagga cctcggatat gccaaagaag agattagggg agactcagca
      901 gaaaagaaat caaatcaaga gcttagaaat ttaggtatcc caaggataat cgatgttaag
      961 aaaggtccgg ggtctgtcat gcaagggatt cagtatctgc tgcaatatga ctggatagtt
     1021 gatgaaagat gtgtcaagac cattgaagag ttagaaaatt atacctggaa aaaagataaa
     1081 aaaacaaatg agtatattaa cgacccagtc gatagttata accactgcat tgacgcgatt
     1141 aggtatgcga catctaatca tttcttgaca ctggacaaaa aacaatccaa tagctttaat
     1201 attttccgca aagcaggttt cggactctag aaaggagaac aatgttatac acagaaacgt
     1261 ttaaagacag cacaggtaat gctaaattac ttgagtttag attccatcgt gagtctcgta
     1321 tgaggtatca gacaagcgat ttaagcggcc tttttgacga agggtataaa ctattgcttg
     1381 actatatcaa acaccacgaa agcaagcaaa aaccacgcat acaggagctt ttagactatg
     1441 ctgagggtaa taatcataca gtctgcgaat caggccgcag acgagaggct gatatggcag
     1501 acagtcgtgc tatacacaac tacggtaagt atatctcgac ctttaagcag ggctatttag
     1561 ttggaaatcc tatccgcgtg gaatatgagg acaatgatga tgctaaaaaa caattgttca
     1621 aggagctggc ggataaaaat aacttccacc aacttaaccg tagacttgtc aaggatttat
     1681 ccaaggtagg ccgcgcctat gaacttatct atcgcagcat ggacgataag acagaggttg
     1741 tgcgattaga tccacgagaa acctttatta tctatcaagc tgatgttggg caagctagcc
     1801 ttgtgggtgt gaggtactat aacaagagtc agctggatag aacaaagaaa acagttgagg
     1861 tctacacaga taacgagatc atttactttg attatgatgg gcaactgaca gaggttgata
     1921 ggcggccaca catttttaaa tctgtaccta tcacagagta tctcaatacg gacgatggcc
     1981 ttggtgatta tgagacggag ttgtctttaa ttgacttgta tgatgcagct caatcagaca
     2041 cagcaaacta tatgcaagat ttgtcagatg caatcttggc tattattggt cgagtatcgt
     2101 tcccgagtta tgtagacacc aaggaaaaag ccattgaata tctgcgtgct atgcgcaaag
     2161 ctaggttgct aaatttagag ccaccagtgg ataccgaagg tagagaaggt tctgtagatg
     2221 ctaagtatct ctataagcaa tatgatgtca acggcacaga agcttataaa gatagggttg
     2281 tgcaagatat ccacagattt accaacacac cagatatgtc agatagcaaa tttgcaggca
     2341 cgcaatctgg agaggcactc aagtggaaag tctttgggct tgaccaagag cgtgtagact
     2401 tgcaagcact gtttgagcaa tctctaaaac gtagatataa gcttatcgca agagttagtg
     2461 agctgttaaa agaaattgac ggatttgaca ttagcaaact taaaattact tttaccccta
     2521 acttaccaaa atcgctacat gaaaaaattg aagcttttaa agcacttgga ggggagttgt
     2581 cgcaaaaaac aacaatgtct attacagata ttgtggaaaa tcctgataaa gagattgctt
     2641 ccatcaacga tgaggctaaa aatcgtagtt tattggcgca aaagatggag tcagaaggta
     2701 gaatgacgga tagggagtta gctcgtgact acaatcatga ataagagtaa atattggcgt
     2761 gatcgtgtta aaaaagaaat ggacgcaaaa gaggcagatg atatctccct tgaacagtcc
     2821 atgaaacaat tacacaatta tcattttaga aatatcgaaa aagaaattga gtcattttat
     2881 caacgttacg ctgataaaga gaaaatagac atcgcagaag cccgtaagag agtttctgag
     2941 cttgacattt ctgcttacca gaagaaagct aaggaacttg ttgtaaaggc tgagaagcta
     3001 cgaaaagagg gtaagacagt aacgagagat gactttaccc accaagaaaa tgcagacatg
     3061 gccatctaca atttagcgat gaaaactaac gctttagaat tgttgcgctt gaatatcgac
     3121 ttggagatgc aggagctcgc aaatggcgaa cataagctaa ccaagacatt tcttgacgaa
     3181 ggataccgca aagaggttga gttccaagcg ggattgttag gactgtcggt tgctagccaa
     3241 gcaagcgtga aagggttggc tgacgcagtt attaacgcta atttcaaagg cgcaaaatgg
     3301 tcggatagca tttgggacag acaagataaa ttacgcagca ttatatccca gagcgtacag
     3361 agtgctatct taaaaggtaa aaatggttta actattgcaa gggatattag acgagagttt
     3421 gatgtgtcag tgtcttatgc aaagcgaata gcaatcactg agcatgcaag ggtgcagatg
     3481 gaagttagta gattatccat ggcggagaat ggctttgcta tgtttgacat tatcccagag
     3541 cctaaagcat gtgatgtttg taaagacatt gctaaacaag gtccatatca catggataag
     3601 tggcgaacag gggaaaacac gccgcccatc catccttatt gcaggtgtgc agttgttgga
     3661 gtggaagaag aaaatagtag taatcatgaa tcacttgata agcttattaa aacagagtat
     3721 aatcaaagta tgaaagagtc atcgacttat gctcgtaacg ttttgtcggc agtgtcattg
     3781 atagagcctc gaattacatc gcaaattaag catattgtca agcaatccaa cggtaattta
     3841 caaggacttg attttagatt aaaaagtcta gattctttgg ccagaaagat ctctactgat
     3901 agcttgttgg acgatatttc accggaagaa gccgcaaaca acataaatga tgcattacgc
     3961 tatacagctg tatttaaacc agataatttt tttgatgatt atcatagcat gaaaaatgca
     4021 ttggtcagag atggttttaa aatcgaaaag gtgaaaaata cttggctaga tgatggtcca
     4081 tataacggtg ttaatactgt tgtatcaaaa gacaatgtca agtttgaaat tcaatatcat
     4141 acccaagaaa gctttgattt aaaaaacggg aaactgcatg aattatatga ggagagaaga
     4201 cttcctaata taacacgaaa acggaaggct gaactagaca aaatgatgtt tgagcttagt
     4261 aaatctttaa ctaaacctaa ccaaatagaa agggtgaatt gatatgatta caaaatattt
     4321 ttttataaaa accgaacacc ccaaaattgt tagatattct aatgggttaa cagaagttta
     4381 taacagcgca aaaggctggg aagaacaaga agcttggtac gatcgtctat tctttagcga
     4441 tttcagtgat tttgaagagg ttacagaaaa agaagctaaa atgtttattg cgggattgac
     4501 agcggcatga gtattgtgga gctagctttc agagtggcta aaaaagccca ccttggacag
     4561 gttgataagg ccggtgtcga ctatattaag caccctataa ctgttgcaag ttttgtaaaa
     4621 actgatgaag aaaaggcaac ggcttatctt catgatgtta tcgaagatac aagtttgact
     4681 ttacttgact tggaagagta tgattttcct cgaagtgtta tagaggcagt tgatatactg
     4741 acaaagaaaa aaggacagga ttatcaatcc tatctaaacc ttgttaaaac aaataaactt
     4801 gcaagaactg taaaattagc tgatttaaaa cacaattctg atttatctcg tctctctgaa
     4861 gtaactaaca aagatttaaa acgctataaa aaatatcaag aagctatcaa atatttaaac
     4921 aattaaacaa caacagacgg gcaaccgtct ttttttgtac cccaaaaaca ggaggaaatg
     4981 atgttgaaaa tagtgaaatt tttgaaatat gtttggattt ataagtgtaa acctgtcagt
     5041 ccaagtcttt atgcatcgag tcggattgag tacttcaaac ctcttggtta ttactgggaa
     5101 aaagcaacga taggagaaag caatgaataa acgaatcaaa aagaaacgta aactagaaac
     5161 agtagtagtg atgctggttg cggaaaatgc cttgcaggct gaagcgctca taaatcaaaa
     5221 caaagaaatc atggagctaa aatcaatcgt tgagcgaaac gctctggcaa caaacgaaga
     5281 gttagcgact gttaaagaca ccgttttaga caaccaatca gttatcaagg caattggtga
     5341 cacggttgac tacatcaagc aaaattacaa acgtaagtgg gggaagaaat gaagtatctc
     5401 aagaaaaagt aatagtaagg agttattttg aaagtcaaag agatagcaca ggtgtttaat
     5461 gaatattcgg atttttttgt ggtacaaaac ggtaaatatc tacctggtga cagaactagt
     5521 ttttttctag attgcgaatt ggaaatcaaa gaaatatcta tcggaattcc tgattgctta
     5581 attattgaag tataaaaaat tcaaagtcgt agcaatacgg ctttttattg tgccctgagc
     5641 atggcctaaa aaggctcaaa ttaatcacta gcgtggcttg tggataaata cacctaatag
     5701 agactagaaa acatgaggcg cccgttttcg tggctctgca gtgtgtttaa aagcaagact
     5761 agcgtgggag gaaaaaatga ataaaaaact attagaaaaa ctttttaaat gtgctccaga
     5821 tactggcaca ggttcaggag gagcttctga tgcagatagc caacaatccg aaacagatgg
     5881 agaaccatct agtgaagaca gctttaaagc tccacagtcg caatcagagt tagatagcta
     5941 tacgaataaa gcaatccaaa aggcattgga aaatcaacgc aaagatgaag ctaaacgaat
     6001 agaagaagct gtaaaagctg ctttagataa agaaaaagac tactccaagc tatctgaaga
     6061 agaacgtcag cagcgtgaat ttgaagatag taagaaagcc tttgaagctg aaaaagccaa
     6121 gtttgaacac gataaacttg tagtccaagt cgaaaaggat cttatcgcaa agggattgcc
     6181 ttctgagttt gctgaattgc ttgctacaaa agatgcagaa aatgcgctag agcaagtcaa
     6241 aacattcgaa gcagcattta aaaaagcagt agctgatgaa gttaaaaaga ccgtacgaca
     6301 acttactcca tcaactgggg caggtgcaat atcaacacaa acaaactatg gggcgaactt
     6361 ggcgagtaag atcgcacaac aaagcaccac attattttag gaggaaaaaa atgaataaac
     6421 gtaaagtaac aacatcaaaa gagattctcc acaatctcga atacgaagct attacagtca
     6481 ctttagattc aagcacagtt ggcaaaaaag ttattccagc cggtacagtt ttggccggtg
     6541 tatcggattc tgtttttaaa gatcgcaaac aaaaagtaaa aactgtggca aatcacgagg
     6601 tcagcggaga gagcaatatt tgtggaattt tgttaaccga tgttgatttg acagatggtg
     6661 ataaagcagg tgcttgtgtt tatcgcggta ctgtcaacgc agataaactt gctgattcat
     6721 caattgcaga aaattttacg gaattggcga caaaactacc acatgttgtc tttattaagg
     6781 gaggtaagta agcatggcat tgatccacga aattatcaca tcggaaaaca tcaaaggttt
     6841 ttataatgct aaaaatgaga acattgataa aacgttaggg gaaaaagcat tcccaccaaa
     6901 acagcaatta gggcttaagc tatcctttat caagggtgcg gcaggaaaac ctgtgacact
     6961 taaagcggcc gcttttgata ctaaagtacc tctacgtgac cgcatggcag ttgagctgct
     7021 tgacgaagaa atgccttact ttaaagaggc tatgcttgtt aaagaggcag accgtcaaga
     7081 gcttaacatt atatctcaaa caaaaaatag tgatcttatt gacacagttt tagcggcaat
     7141 ttataacgat aaggtaacgc ttatcgcagg cgctaaagca cgtttagaag caatgcgtat
     7201 ggaagtgctg tctaaaggta aaatccacgt cgcatcaaac ggtgtcatga aagactttga
     7261 ttatggacta gactcttcgc aaacaactaa gccaagtgtt aaatggtctg aggcagagac
     7321 cgcgacacca cttaaagaca ttgaaggtgc aattgaaaaa atggcagaac gtggctttgt
     7381 gccagaagca attatcatga actctaagac atttagtttg attaaaaacg ctaaatcaac
     7441 tcttaaaatc atcaaaccaa tggcaccaga tggggcagct gttaccaaag gtgatttgac
     7501 gacttatatt gctgatgaac taggactcaa aattttgttt aaagatggta tgttcattgg
     7561 tgacgatggc aaatctcgta agtatttccc agatggcttt gcaactttgg tacctaacgg
     7621 caaccttggc tacactgtgt ttggcactac tccagagcaa tcagatctca tgggtgggca
     7681 cgcaacagat gcagatgtgt cgttggttga gactggtatt gcaatcacaa ctactaagac
     7741 aactgatcca gtaaatgttc aaaccaaggt atctatgatt gctttgccgt cattcgaacg
     7801 attggaagaa gtgcaaatta tcgactccat tgaccaagta taaggagggg gttatggctg
     7861 aagttattaa aacttttagg gataaagaaa ccactaacac ttactacgta ggagacgatt
     7921 acaacggaga ccgcattgat gagttgacag ctaaaggata cctatctggt gataaggttt
     7981 ctgctgccgc tatagagatt gaccttgaca aattaaaggt tgacgaaatt agagcaaaac
     8041 ttgatgagtt aggcgtcgct catgacccta aactaaaaaa gccagaatta ttagaacttt
     8101 tgaaacagtc agctagctag gaggtgttta tgcaaaagat aaacacagat agcattatag
     8161 ctaacgtaaa actcgattta ggtattgatg acaccttgca agacagtttg ctcaatatgt
     8221 tgctaaaacg tgttacagac cattttaaag cggaatacgg cgttgatgat atagacaacg
     8281 ccttttcgtt tgttttggaa gactgtctaa ttgctaggtt taatcgcaga gggtcagaga
     8341 gggctaagtc ggaagaggta gagggtcata aaacaaccta ctatgacttt ttaaatgagt
     8401 ttgagcctta cgacaaaatg attaagtcca accttaattt gattaaggat aattctcgta
     8461 aagggggatt gtacttttta tgagatatgc agataggatt acgtttgtta aggcgacaga
     8521 tgaacaatat gaccctgatt taggtgagta cacatatacc gaagtcatga tcaagacatt
     8581 gccttgtttt gtcatggact taggtatggc taaatctgtg cagattttcg gagactatca
     8641 aaaaacacga aaagttgttt atttgcgcca accttatacc gatttgttag atcactgtct
     8701 ctacaaaggc aaaaagtaca aggtacaggt ggataagcaa tttaatactg ttttttatct
     8761 ggagggagat gattctattt gtagctgata tatctttaaa agtagttgga acgacagggc
     8821 taaagaataa acttgaactt attgccaaaa aagaggctgt caagaagatt gttagagata
     8881 atggaaaaca actacacagg aaaatggtcc aaaaggcagt atttaccaaa ggtcattcca
     8941 ctggtgctac cagaatatcc atcacaatgc agattggtga tgatggtttt agtgttacag
     9001 taaaacctgg cacgcattat gcaggttatt tagaaaaagg cactcgcttt atgagtaagc
     9061 aaccttttgt gttgccagct ctaaaagagc aaaaagtaaa attcagaaaa gatttggagg
     9121 cgcttgtcaa atgattaaaa ctagagatca atctattttt gacgagatgt ttaagcgtat
     9181 tcagtcttta ggttttaaag tttatgatta caaaccgatg actgaggttc cttatccgtt
     9241 tgtggaaatg gaatctactg atgcagaata tattccaaat aaagatgaca ttaaaggctc
     9301 tgttgacctc gtactgtctg tttggggatt gcaaaaaaaa cgaaagcagg tgtctgatat
     9361 ggcatctgct attttttcac aagctatgtc agtggctagt tctgacagct tttactggtc
     9421 gttaaatatt cgtcaatcat ctatccaagt gttagatgac acaacaacag tgacacctct
     9481 caagagagcg attgtcacat taagatttaa tttaagatag gaggtcgcaa tgccaggacc
     9541 aagtagatta ggatccaaag atgaagacca ctccacacaa gaaaggaagg aaaaaatggc
     9601 agcgcaagat caagtacaat tagaagcaaa acaagggatt catgcaatcc tattattccg
     9661 tttgttaaaa gaagcatcat cagaaaaagc agctaaactc gcttttcaaa cggaacacga
     9721 agttggtaaa agtcgtgatg tcgacggtca aaagactaaa gatggtatta tccagtctgt
     9781 cggagcttta gaatacgact ttaaagcaac atctatttta gccaaaggtg acaagttagc
     9841 agcaaaacta gaagaagcca tggaaaaagg tgagcttgtt gaaatttggg atattgattc
     9901 cgaaaaagca agtgaagaag cttgatagca aaggtaaata tccagctacc tattaccaag
     9961 gttacatttc aagtttcggc gctaagaaaa atgcagaaga aaatattgaa attgaaatgg
    10021 aatttgccat taatggcgtt ggtcaaaaag gatttgcaac attgaccgaa gaacaaaaag
    10081 cagctgtaca gtacaaattt aaagatacaa cagcaggtta atcaacaagg ccagttaatt
    10141 actggtcttt tatttttaaa tttttaaagg gggaaaagaa taatgcaatt ggaaattaaa
    10201 ggtaaaactc ataacatcaa atttggcaca cgatttgttg ctgaaatgga taagaatcac
    10261 attgcagaac gtgaagggat gaagtttggc gctggtttgc aatcaactgt tccgtttttg
    10321 tttgagcgta acgttgtgac acttgctgag attatctata cagggacaat cacagagtca
    10381 ccacgaccaa gcttaaatga tatttacgac tacatcgatg aggctgaaga tattgagaag
    10441 cttttcgatg atgttttaga tgagttgcgc caatctaacg cgtcaaagtt gtttatcacc
    10501 aaactggaca aaaacatagc ggagatggca accgaagctt aaagagttca accaaaaatt
    10561 attcttcaca agaaagcttt gagatgattg tccttaattg tgttagatat cttggcatga
    10621 ctgacattaa tgagattggt cggttgactt tgtatgaata tgatttattg atgataggta
    10681 aagcgctagc ctctgtagac gaggcatata aagctcacaa gcaagcttgg ataaatcacc
    10741 aggtctcagc tacgaggctg gtcggtggtg gtaaaaacaa aagagaagtt cctgtttata
    10801 aaacattcaa ggaatttttt gattatgaaa cagaaatcaa gaagataacc aatgaaattg
    10861 atgaaagcta tgacaagaaa gcaatggatt tacttttaaa agccaacctt taaatagaaa
    10921 ggaagttaaa tgggagaatc ttattcagtt gaagcggtgt tgacagcggt tgataaaacc
    10981 tttggtaaga ctttaaaatc agcagttcaa tcaattgaag gactagaaaa gcgttcaaaa
    11041 ggcttctcgg cggtgtctca aaaggctggg tctatgttta aaagcatgct tggagctaac
    11101 ttagcaggtc aagctattac agcgctagga cgtacagttt catctggact tatttcgatg
    11161 atcggcgaaa tgaatagctc agcaaaagcg tggaaaactt tcgatgccaa tttagcagat
    11221 atcggatttg gcaaacagca aattcttgaa gctaaaacag ctatgcaaga ttacgctact
    11281 aaaacaatct actcagcatc agatatggcc agcacatatg cacagttagc tgctgttggg
    11341 gtaaaggata ctgggaaact cgtaaaagct tttggtggtt tggctgcatc tgctgaaaat
    11401 ccaaaacaag ctatgaagtc aatcagtcag cagatgacac aagctgtggg aagacctaca
    11461 gtagcgtggc aagatttcag aataatgctc gagcaagctc cagctggtat ggctaaagtg
    11521 gccaaagcta tgggcaaaaa ccttaatgaa cttgtagccg acattcaggc tggtagagta
    11581 aaaactaaag acttcctaga agcagtaaaa caagctggta acgacaaaag cttccagaag
    11641 atggcgactg aattcaaaac tgtggaccaa gccattgatg gcatgcgtga aggtttatcc
    11701 aataaattgc aaccagcttt tgaaaaagtg aaccaatttg gaattagagc gattgaagca
    11761 atcgggaaac aactcgataa aatcaatttt tccaaatttg ctgcaggcct tggtaaattt
    11821 ctcgagggcg tgaacattga tagtattatt tcaagaatat caacatcaat ttcatctatc
    11881 gtttctaaaa taaaaggatt ctgggacgga tttaatcaaa ctggagcaat cagcgctttt
    11941 tccggtgctt tacaaagtgt ttggggagcg ttaaaaaata ctgctaaagc catgagtgga
    12001 ggaagctgga agaccttcgg gtcaatcatt ggcgaaattg ttaaacatgt ttctaatttc
    12061 gcaagagtga ttggagatgt cgttggcaag atggatccga gtagactaaa aagctggata
    12121 gctactcttg cagctgttgg tggtggattg aaaatctttg agaaattaac aggtcaaagt
    12181 gttattggat cttttttaga caaaatcggc tcaaaattca aaatatttgg aaataaagcc
    12241 aaagaaggga cagaacaagc ctttaacgga gtcaaaagaa gtggtggcat tatcagtaaa
    12301 atctttaacg gtttgggtaa tatcgttaag tctgccggta cagcgatagc gactgctgca
    12361 aaaggtatcg caactggttt ttctatcgcg tttaaggggc ttgggtctgc catttctatg
    12421 gtaccgccag ctacatggct agctttagga gcagctattt tagcggtagg agcggctttt
    12481 gccttggcag gaactcaagc tgatggcatt agtcaaattt ttaaaactgt tggcgatgtc
    12541 gttgtacaag ttttacaaca ggtcactaac agtctagcta ctctaattcc tattattgta
    12601 agcgctattg gctccatatt accaattgta gcaggggcta tttctcaagt cgtcgcagca
    12661 gttgctggcg gattatctca gattattaca gctgttgcta atggtgtatc aactattatt
    12721 ggggctttca caggtctact tggtggtgtt tctagcgtca ttacctcaat tagtggtgtt
    12781 atccaatcgc tggcaggtgt aattacctca gtatttaatg gcatagcaac cattatttcg
    12841 tctgtagggt ctgcaattaa agatgtatta acgggtctcg gcagtgcttt taaaggattc
    12901 ggcaacggtg taaaatcagc cttagaaggc gttgggacag taatcaaatc atttggtagt
    12961 gcagtcagaa atgtccttga tggtgttgcg catattttcg attctatggg taatgcagct
    13021 cttaatgctg gtcgtggcgt caaagaaatg gctaaaggca tcaagatgct tgtagattta
    13081 tcgcttgctg atttagtcgc aacgcttgga gcagtcgcga caggtcttgg gaatatggct
    13141 ggctctgccg gtcagatgac tacgttaagt tctgccatga gcgaagtagc caatggtatg
    13201 gcgcgtctag gaacaagcgc tacgatagca attactggat taacagtttt tgctactact
    13261 ataacaacta ttcagaccgc aattgcaact ctaccaacaa tcctaactgc agccgctagt
    13321 ggttttaggg agatcgggga ttcggcaact gcagcagttg gtcgaatcca gacttttgca
    13381 gctggtacaa ctgttgttgc atcagcgttt gctagtatgc aatctatgat tcgatctgcc
    13441 atggctgcaa tagtaagcag cattataaca tcatttaacc aagctgcctc tcaaatacaa
    13501 tcaattttat ctcgggtgct atctcaagct aggacatttg gatctcaact agagcaacaa
    13561 atgaggcaat cgggacagcg ttcaggacaa aatcttgctc aggggttgtc ttctcaacaa
    13621 ggtgctgtta ttaatgctgt ttctagcatg gttaatgccg cggtatcaag agcaaatgca
    13681 ggtgctagtc ctatgcgtca agctggagcg tacatcggac aagggcttgc gcaaggtatg
    13741 tattcagcgc taggagctgt aacagcagca gcaaacgctc ttgtagcaca agctgagagg
    13801 gcagcaagag ctaaggcgat gattcactcg ccatctaggt tatttgcaaa acgagttggt
    13861 caatatatcc ctcaaggggt agccatgggg atatataaaa acgctgatgt cgttgatgat
    13921 tctgtaggtg agctatttga tagtatcaat agctttgatt ttaatattgc ggatagattg
    13981 acaagtattg gcgctagatt ccaaggtgtt gtcaaatcag aaagttcgca atcgttgtcg
    14041 cagcaacaag agtttgtaca tacagctcaa ccagcgtatg taaactttag tttaggcgga
    14101 aacgaatacg aagcatttgt aagtgacatc actaatcgac aagcaaaaat tgaaaaaatc
    14161 agactaaaga gaagcagctg gtagttgttt ctcttagttt tatgaaagga gtaaaatgta
    14221 cgaatttaac gatactatca gagggactcc gaaagttact ttcaatttaa aaacaacaat
    14281 tggcgaaaag gtattagaag aagagctcaa taatgattta ggtaccttta ggacattgac
    14341 cgtttctggt cgtgatatgg tggacttaga acaccagaca acaagtgttt tagggcgaga
    14401 tggcgagtat ttccacaatg ccacagttga agtcagaaaa ctagaaataa aagctaaaat
    14461 tactggaaaa gataaccggt caatgcgttt gcaatatgaa aaattaaaca gattaattgt
    14521 tagtcataat caagtttttt tatcattttc agacgagccg gacagaaatt atctaggcat
    14581 ctttaaatct aaagatatac cagaagaagt ttctaacgaa caaatcattg gcttggtttt
    14641 catctgttat gatccattta aaatgtcaga tataaaaacc aaaaaaggta atactgttca
    14701 aaatgatggc ctatttaata caaaacctat cataactctc aacctctcat catcaacaaa
    14761 agaaattagg ctgctacacg tcgaaagtca aaagtatatc agattaactg gtacttatac
    14821 tactgacgaa atcaagattg atatgacaac aggtaagatt acccagaacg gccgtaatat
    14881 tcttagtgat ttagacatgg ttaacagtcg ctattttgat ctattacctg gtaaaaacac
    14941 tttgcagtgt gataatgcaa cgattacagc tgatttcagg gaggtttatc tatgatttat
    15001 ctctttgata agctggagca attagttgct actgttggta ctgatgactt gctctcatgg
    15061 cattttaagg tcaaaaataa tgattgggat caagctagtt ttgaggtacc tgttgattat
    15121 gacattgagc cttttgttta ctttggtttt tttaactatg atccaagcca aaaagaggac
    15181 gtttttaaac tctttaaagt cattgattac aacctagaag atagcaagta ttataaaggc
    15241 ttagataagg ctgagagtga ccttgatact attgctatta tcaaagacaa gcgctttaga
    15301 caatcgtccg cagatgcttg tattgatgga gctttagagg gcactggtta tcaagttggt
    15361 aaagttgagg gcatttccga gatcaggacc cttagctatt attacatcag cccacgagct
    15421 gccatgatca agatgataga agcttttaac tgcgaattta atgtcagata cacctttgtt
    15481 aataacaaaa ttactagtcg ctatatcgac cttaaaaagc gatttggcaa gccaacagga
    15541 aagcagtttg agcatgggaa taacttatta aaagtcgtct atgaggaatc aacagatgac
    15601 atcgtgactt gtctgattgg ccgaggcaag ggcgaggaaa tccaatatga tgaaccagag
    15661 gcaaaggaag ttgaaggaca cttaccagag gcagaaaagc gtcaaggtta tggccgaaga
    15721 attgaattta gcgatgttgt ctggtcagtc gaaaaaggcg actcgataga caaaccagct
    15781 ggtcaaaact ttgtggcgct agatagtgcc agagaagaat acggattgtc tcaaaatggc
    15841 gagctaaaac accgatgggg ggtctttgtc aacgaggaaa ttgaggacaa ggcggaactc
    15901 ttaaaagcca catgggatca attgcagcgc ttatcaatac ccatcagaat ttacaaggcg
    15961 gaaatcttag atattggccc cgaaacgtgg aaaggtgact cagtagccat tatctacgat
    16021 gaggtaaaaa tagcttttga aactcgtgtt gatgagattg atattgataa gctaaacttt
    16081 aacaggtcgg tagtaactct cggtgattat agcgttgtcc aaaaccgcga agcaaggtca
    16141 cgcaaggaag ctgtccaaaa catgatcaat gatagcatag aaaacatcac cggccttggc
    16201 atgaacttac aagaattttt tcaaggtatt gaggaaaaaa ttgccactgg caaaaaagag
    16261 atggaagaca attggcgtaa ggttaacctt gaatttgata actttaaaaa attaatcgaa
    16321 caagagggac gtaactttag agagcgttta gaagctgaaa caaaggaact agatgaacgc
    16381 aaccaaaaag aactcgatga atttcgcgaa accctcaaaa atctgtcgct gcccgaggaa
    16441 gccattaaaa aaataaccga ggccatcaaa gttgatgata tcccatcgct aaaacaaagt
    16501 tttgacgagc tcaaaaacga agtcagcaag aacagcgaaa aatctcgctt aaatgctgaa
    16561 atcatcggca cgaacggtaa gacccgctat aacaaaaatc tcttggttgg tgaacctaat
    16621 cgcaccaaga cctatgatca ggattttgtg gagatagaag caaatgacgg tggttttaga
    16681 cgcggtgaga catacacgat tagctttagt cagacatgtg agttgctaaa aaaagtggct
    16741 atcacgctga cgcagccgca taacaaaggt ctcaagctgg tgctgacacc aaccaaggct
    16801 aagatggagg cgcagacttt tgacctaacc aaggacatag aggttatcag cgtctatcct
    16861 ttgagctaca gagctgtttt aacaggtgac tggtataaat ctaagcagat ggattttaat
    16921 gcggcagaag tgcaggattt agctctggag atgtcttata gagacgttgt cgatagcaat
    16981 aatgctagtt tgattttgga ttggtcctca aatccagatg ttatttttga tggaaatgga
    17041 ggtagttaat gtcagagact atatcagcta tagttgtgca taaaagcatg acaaaaaacg
    17101 agtgggagtc tagtgacatc attttgccac aaggccagct tgtctatgag tctgacacag
    17161 gccatagtaa atttggcgac ggtaaaaata gatatgcaga tttgatctat caaggtggac
    17221 cacctggggc acaaggtccc caagggccag ctggcgaaac cggtccacaa ggcccaccag
    17281 gccctactgg tcaacgtggg gaaacaggcc cacagggtcc acctgggcca caagggccgc
    17341 caggagcgga cggtaaaatg acgtttgagc agctcacacc agagcaaaaa cagcagctta
    17401 aaggtgctgg catacaaagc atatcattgg attatgaggg ctatttgaca atacagctag
    17461 ataatggcca atcgtttaga tcagatatta gcttaaaagg tcctcaagga gagccgggga
    17521 tcaatggtat ggacggtcca agaggcgcaa cgggtcccca aggaccagct ggtgatccgg
    17581 cgagcatacc tgacgatgtt gtcagacgtg gtgagttagc tgcatatttg cttaaatcag
    17641 agtataaagc caaaggcgca ggctctgggc taagctacaa agttgtcact caatcagagt
    17701 atgatgatct gtatgattac agcgacaatg agttgatact cgtgacggag ggttgacatg
    17761 gcatataagc tttacactaa agctgatgtt ggtgacaaca tgttgcttgt tgttggccat
    17821 ttgcctgaca atacaaagcg attaaaaatc cagcgtgaga cgttagatgt attgagtatt
    17881 acccactata gctcttatga tatggtacaa ctcaagtcga cagtcaaaag atcccacagc
    17941 aaaaatacag ttgttactct tgtagctgca gctgctagca agcccaaagc taagccaaag
    18001 cacgttttaa actttgctaa ggctaataag gtctatctag gcagcactcg tgtaatagcg
    18061 gtttatctgg gtgatcgact gctctggtcc gacaaagaca gcagcgggaa caaaactgtc
    18121 tctgttgtgg ggagtcttga tatcagacaa tcacaaaaaa tgctgtattt gtacttaata
    18181 gcgtcagaca ttgcagatgt caaaagcaag cgcattaaat cgatagcgat aaatggcgtt
    18241 aacctgtcaa gcgctgcaca aatcaatttt gaggatagcg actattattg tctagtgaca
    18301 atcgagcgag ttgctaacat caaagagatc aaaaatatag cgcaaaaaaa caaaatcacg
    18361 ctagagtttt aggaggtaac aattgagcag agacccaaca attgtaatag acgagacaaa
    18421 cctcgttatt ggcacagatg gccgcatgca ttacacgttt actgctagtc aagacaacca
    18481 aaaggtcagg ctaaaaagca actgtttagg cacagcgcat tttaaccagc tgatgattga
    18541 gcgaggagac caagcgacgg actacgttgc gcccgttgtt gttgagggta caggacaggc
    18601 aacaggcgtc tttaaaagtc tcgaggagat gcttagtggc ctaaagtcaa ttaaactgga
    18661 gctaacagat accaaaaact caaatctgtg gtcaaaaatc aaattgacga caaatgggct
    18721 tttgcgtgag tatcatcatg atcatatctc gaccgagatt gtcgagacag cagctggtat
    18781 tgccaaacgg attgtcgatg atactggcca aaagctggca ctaatcaatg agactatcaa
    18841 aggtgttaag cgtgagtatc aagacgcaga tagacagcta tccgcgagct atcaagcaag
    18901 tatcgatggc ctcaaagccc agctggccaa cgacaaaatt ggcctacaag ctgagattaa
    18961 gctgtccgcc caaggcttgt cgcaaaaata cgacgatgag ctgcgcaagc tatctgccaa
    19021 gattacaacg acatctagtg gtactacgga agcctacgaa aacaaactcg agggcttacg
    19081 ggctgagttt actcgtagca accaaggcat gcggacagag cttgagtcgc aaatcagcgg
    19141 cctaaaagca gtacagcaat caactgcaaa acaaatctca caagagatca aggatagggc
    19201 aggggctgtt agtcgtgtgc aacaggatct agatagttac caaagacgct tgcaagacgc
    19261 agaggataat tacagtagct taacccagac cgttaaaggc ctgcagtcaa ctgttagcga
    19321 tcccaaaggc aaaatccagt cacgatttac acagctgcaa ggtcaaattg agcatcgtgt
    19381 gactagagat ggggttatga gtatcatcaa cgagtcaggc gatagcatta agctagcgat
    19441 ccaaaaggct ggtgggattg atgctaagat gagcgctaaa gagattatct cagcgattaa
    19501 tcttaatggt tatggcgtca gaatctccgg tgagcgtatt gcgctggacg gtaatacgac
    19561 cgttaacggg gcttttggag ctaaacttgg tgagtttatc aagctcaaag ccgatcaaat
    19621 tattggtggt tcgattgacg ctgctaagat tagagtgatc aatcttaacg ctagcagcat
    19681 tgtcggctta gatgctaact ttatcagggc taaaatcgaa catacgatta caagtttgct
    19741 tgagggtaaa gttatcagag ctcgcaacgg agcgatgatg attgacttgt taaactctaa
    19801 aattgacttt aacagcaacg ctaccattaa ctttaataac aaggacaatg cgcttgtacg
    19861 taaagacggt acccacacag cctttgtgca ttttagcaat gccacgccaa aaaattatac
    19921 aggtagtgcg ctttacgcct cgatcgggat aacctcgtca ggtgacggga ttaacagcgc
    19981 gtcgagcggt cgtttttgcg gtgctaggtt ttttaggtac gc
//
LOCUS       DARYXW010000034        19912 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.034, whole genome shotgun sequence.
ACCESSION   DARYXW010000034 DARYXW010000000
VERSION     DARYXW010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19912)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19912)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19912
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.034"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(<1..424)
                     /locus_tag="TV191_000990"
     CDS             complement(<1..424)
                     /locus_tag="TV191_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507517.1"
                     /translation="MVKLSKRSKIAMSFLIVFCGIFFVAQKRFGSSDQSFTVRPDADF
                     YIVGYHNIEGYQLTNEQPQKISDAKLEVVKGQINQVVKRAELSNRYLVFSEEGPPLGA
                     IGRLIALDFQKGNVTYHPTADYAFTSSGVSPDYYFTSTA"
     gene            1025..1843
                     /gene="proB"
                     /locus_tag="TV191_000991"
     CDS             1025..1843
                     /gene="proB"
                     /locus_tag="TV191_000991"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEL1507518.1"
                     /translation="MMKRQFEDVKRIVIKIGTSSLVLANGKINLEKIDHLAFVISSLM
                     NKGKEVILVSSGAMGFGLDLLKMAKRPSQLAKQQAVSSVGQVAMMSLYSQIFAHYQTT
                     VSQILLTRDVVVFPESLANVTNAFESLISLGIVPIVNENDAVSVDEMDHSTKFGDNDR
                     LSAIVARITRADLLIMLSDIDGLFDKNPTIYEDARLRSHVTEITEDIIASAGGAGSRF
                     GTGGMLSKIQSAQMMFEHQGQMILMNGANPRDILRVLEGEKLGTWFKQIERGDA"
     gene            1843..3090
                     /locus_tag="TV191_000992"
     CDS             1843..3090
                     /locus_tag="TV191_000992"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEL1507519.1"
                     /translation="MTIEQLGQRAKAASRALVSLTTKDKNQFLAFLAEELVAQTDMIL
                     TENAKDLAKAAEHGISEILCDRLRLTADRIHAMAQGVRQVADLADPIGEVIKGYTNLD
                     GLKITQKRVPLGVIAMIFESRPNVSVDAFSLAFKTNNAIILRGGKDALYSNMALVRLI
                     RNALEASAITPDAVLLVEDTSHAVAEELMQATDYIDVLIPRGGARLIQTVKEKAKVPV
                     IETGVGNVHIYVDEAADLEMAVKVVINAKTQRPSVCNAAESLIIHEKVGATFIPMLEA
                     AISKVQQVEWRADEQAKALFSKAVLATEEDYAAEFLDYIMSVHLVSSLDEAISWINQY
                     TSHHSEAIITANINAAERFQDLVDSAAVYVNASTRFTDGFVFGLGAEIGISTQKMHAR
                     GPMGLEALTSSKYLINGNGQIRS"
     gene            3110..3526
                     /locus_tag="TV191_000993"
     CDS             3110..3526
                     /locus_tag="TV191_000993"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507520.1"
                     /translation="MTRDLKKQETIRDLKTLAFKLESVIEALKELKRWGFFDLFDNGI
                     LTSWVKRQKISAINESLGDVRNLVCRYQKELKVSELRLPSSLSHTRQDKIFDIWLDNS
                     VTDFRVLKETKQVLESAELLYEAVQQALSHLDVKDS"
     gene            3629..4579
                     /gene="rsmH"
                     /locus_tag="TV191_000994"
     CDS             3629..4579
                     /gene="rsmH"
                     /locus_tag="TV191_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEL1507521.1"
                     /translation="MTNEFHHVTVLLHEAVDMLDIKPDGIYVDATLGGSGHSAYLLSL
                     LGDKGHLYCFDQDQKAIDHAQEQLKPYIDKGQVTFIKDNFRHLKARLLEHGVTEIDGI
                     LYDLGVSSPQLDERERGFSYKQDAPLDMRMDSQAALTAYEVVNTYDFNDLVRIFFKYG
                     EDKFSKQIARKIEQARAIKPISTTTELAALIKSAKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADASIQRAIELLALDGRISVITFHSLEDRLTKHLFKEASTADAPKGLPFIPD
                     ELKPKLELVSRKPILPSQKELMANNRAHSAKLRVARKVRK"
     gene            4583..4906
                     /gene="ftsL"
                     /locus_tag="TV191_000995"
     CDS             4583..4906
                     /gene="ftsL"
                     /locus_tag="TV191_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEL1507522.1"
                     /translation="MVNEKRTQAVSKALQKRIRTFSRVEKAFYATLILTAVTMAVSII
                     YLQSRKLQLQQHITQLNRQISDKRTELNNAKQEVNELSRRDRIVDIAGKAGLSNRNDN
                     IKKVE"
     gene            4910..7165
                     /locus_tag="TV191_000996"
     CDS             4910..7165
                     /locus_tag="TV191_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL1507523.1"
                     /translation="MTKWQRYFLDYVVRDRKTPVQNRLRVGQNMMLLTIFIFFIFMIN
                     FMIIIGTDQKFGVKLSDGAKKVYQETVSVQAKRGTIYDRNGTAIAVDSTTYSIYAILD
                     KSFVSATGEKLFVQPSQYDKVAQILKEQLGMEEKDVIKQLKQKGLFQVSFGPSGSGIS
                     YSTMTTIQKAMEAAKIKGIAFSASPSRMYPNGTFASELIGLASLEENKEDGTKSLVGK
                     MGMEAAFDSILSGEDGIITYQKDRNGNTLLGTGKTVKKPVDGKDVYTTLSEPIQTFLE
                     TQMDVFQSKAQGELASATLVNAKTGEILATTQRPTYNADTLEGLNSKSYSWQNILHQG
                     QFEPGSTMKVMTLAAAIDEKVFNPDETFSNANGLTIADATIQDWAINEGISTGQYMTY
                     AQGFSFSSNVGMTKLEQKMGNDKWMNYLTKFRFGFRTRFGLENEDPGIFPSDNIVTQA
                     MSAFGQGISVTQIQMLRAFTAISNDGVMLEPQFVSRIYDPNTDTYRVSDKEIVGKPVS
                     QKAASETRKYMINVGTDPQFGTLHLKSSGPVVKVGQLPVAVKSGTAQIATKDGTGYLD
                     GGLTNYIYSVVAMVPADEPDFLMYVTLKHPEHWAMVFWQDIINPVLEEAYLMKDTLDK
                     PVAVDTSHEATYQLPDIVGQDTGKSADELRRNLVHPIVLGNGSKIKKVSKKAGTNLAA
                     NQQLLILSNHFDEMPDMYGWTKANVATFAKWTGIDIKYKGSSSGRVVKQSVDVGKALK
                     KVKKITITLGD"
     gene            7167..8174
                     /locus_tag="TV191_000997"
     CDS             7167..8174
                     /locus_tag="TV191_000997"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEL1507524.1"
                     /translation="MFLTILAGLIAFAVTALAMPHFIRLYQLKKIGGQQMHEDVKQHL
                     AKAGTPTMGGTVFLLVATSLSFVFALVYFRDGQSLGLISGILLIVLIYGIIGFLDDFL
                     KIFKQVNEGLTAKQKFTFQIVGGLVFYVIHVMPSGIDAINVFGYHWHLGFLYLCFVLF
                     WVVGFSNAVNLTDGIDGLASVSVVISLLAYGVIAYAQGQFDVLLLIGIMVGALLAFFL
                     FNHKPAKIFMGDVGSLALGAMLAAISIALRQEWTLLVIGIVYVLETSSVMLQVTYFKY
                     TKKKYGEGRRIFRMTPFHHHLELGGLSGKAAKWSEWKVDAFLWALGLVASLIVLAILY
                     L"
     gene            8257..9600
                     /locus_tag="TV191_000998"
     CDS             8257..9600
                     /locus_tag="TV191_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL1507525.1"
                     /translation="MSFHDYHFKHYIQEALDELGFVEPTEVQQRLIPIVSTGRDLVGE
                     SKTGSGKTHTFLLPIFEKLKEEKEEVQAVITAPSRELATQIFEASRQIAKHSKQEIRI
                     ANYVGGTDKQRQLDKLKLSQPQLVIGTPGRIYDLVKSGDLAIHKASTFVVDEADMTMD
                     MGFLSTVDKIASALPKTIQILVFSATIPQKLQPFLRKYLTNPVIEQIKTETVIADTID
                     NWLLSTKGRDKNEQILATLKAIQPYLAMLFVNTKERADDLHAFLAANGMKAAKLHGGI
                     PPRERKRIMNQVKNLAFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITFYQPSDDSDIKELEKLGITFIPKVLKNGEFQDTYDRDRRQNREKAYQK
                     LDTEMIGLVKKKKKKIKPGYKKKIQWAVDEKRRKQRRAEKRAKGRAERQSRKQSF"
     gene            complement(10241..10696)
                     /locus_tag="TV191_000999"
     CDS             complement(10241..10696)
                     /locus_tag="TV191_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507526.1"
                     /translation="MKKAIVSVTLLTVAVLSLSTRFIYSTDYSDLNHKEMARLIQSRK
                     QPVIKYHDNVTINKMITYLAQAKREGILTETFLMNYIFAGEGEYLTKNSRIIADPDGG
                     YWSILEGYEGDGGVKTGIDGVSELNIFSPESTSIGELQEAVLAWYEANK"
     gene            11204..12031
                     /locus_tag="TV191_001000"
     CDS             11204..12031
                     /locus_tag="TV191_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEL1507527.1"
                     /translation="MTKQLQRALFFLLASLGLLAVVTSHEVTARQKEVIRVATDAATK
                     PFTYRKKHSVTGYDIEVLKRVFKGSKKYRLSIEVVPFPSILAGIDAGRYQIGANNFGY
                     SKERAEKYLFSSPISASHYALATKGKQQYKSLADLSGKKTQGIAGSNYMLILEKWNQS
                     HPDQKPIHLTYASESTPFTQRLQLLENGQLDFLFYDAISLTTVAEEQGFDVHVTKLKE
                     QADTAKDGLEYYVFANDQKGKALQSFVNKRLAKLKKSGQLRKLSQAFLGGDFISKVN"
     gene            12408..13211
                     /locus_tag="TV191_001001"
     CDS             12408..13211
                     /locus_tag="TV191_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL1507528.1"
                     /translation="MTSTFLTSGWAWYDKLISLIPEGKLFSWHAVFDAIPDIIRRLPI
                     TLGLTIAGAALGLFLALVFAIVKINRVRILYPIQAVFVSFLRGTPILVQLMLSYYGIP
                     LFLKFLNQRYGFDWNINAIPASIFAITAFAFNEAAYTSETIRAAIQSVHTGEIEAAKS
                     LGMTSAQVYRRVIIPNAAVVATPTLINGLIGLTKGTSLAFNAGIVEMFAQAQILGGAD
                     YRYFERYISVALVYWGISILIEQAGRLIEYNMAIKAPIPTNNSKIGELR"
     gene            13211..13954
                     /locus_tag="TV191_001002"
     CDS             13211..13954
                     /locus_tag="TV191_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1507529.1"
                     /translation="MIKVTHLTKSFSGQKILDDLTVTIEKGQVIALVGASGAGKSTFL
                     RSMNYLEQPDTGSITIDDFAVDFEHITKEDILTLRRKLAMVFQQFNLFERRTALDNVK
                     EGLKIVKKLSDQEATDIARAELAKVGLSDRENHYPRHLSGGQKQRVAIARALAMKPDV
                     LLLDEPTSALDPELVGEVERSIIDAAKAGQTMILVSHDMAFVYQVADRVLFLDKGKIL
                     EEGAPEQIFRHPKEARTKEFFANYAKTYI"
     gene            14064..14291
                     /locus_tag="TV191_001003"
     CDS             14064..14291
                     /locus_tag="TV191_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEL1507530.1"
                     /translation="MLVEIFRFYLEGLLLAAITMVMLCLLWILWRAVTKKDKTILQRQ
                     AFLYEMIMVAILTIPILSFAFMSILVVLKAK"
     gene            14351..15268
                     /gene="trxB"
                     /locus_tag="TV191_001004"
     CDS             14351..15268
                     /gene="trxB"
                     /locus_tag="TV191_001004"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEL1507531.1"
                     /translation="MYDTLIIGSGPAGMTAALYAARSNLRVGIIEQGAPGGQMNNTSD
                     IENYPGYDHISGPELSLKMYEPLEKFKVENIYGIVQRVEDCGDYKRVYTEDTHYDTKT
                     VIVATGAKHRLLGVAGEEEYTSRGVSYCAVCDGAFFRNQELLVVGGGDSAVEEAIYLT
                     QFAKKVTIVHRRDQLRAQKILQERAFANEKLDFIWDSVVKEIQGNDIKVSNVVIENVK
                     TGQVTSHDFGGVFIYVGLIPVTQMVSELGITNQEGWIVTDDQMKTSIPGIFAVGDVRQ
                     KQLRQITTAVGDGAIAGQGVYHYIESLSS"
     gene            15388..16782
                     /locus_tag="TV191_001005"
     CDS             15388..16782
                     /locus_tag="TV191_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEL1507532.1"
                     /translation="MSTKEAKSTKELENGMVRGLQNRHVQLIAIAGTIGTGLFLGAGR
                     SIALTGPSIIFVYMITGVFMFLMMRAIGEMLYYDPDQHTFINFITKYIGPGWGYFSGL
                     SYWISLIFIGMAEITAVASYVQFWFPAWPSWLIQLVFLVLLSSINLIAVRVFGETEFW
                     FAMIKIVAILALIATAVFMVLTGFETHVGHASLANIVDHFSLFPNGKLKFFMAFQMVF
                     FAYQAIEFVGITTSETANPRKVLPKAIQEIPMRIVIFYVGALVSIMAIVPWYQLPTDE
                     SPFVMVFKLIGIKWAAALINFVVLTSAASALNSTLYSTGRHLYQIANETPNALTKALR
                     INTLSRQGVPSRAIIASAVAVGVSALINILPGVADAFSLITASSSGVYIAIYALTMLA
                     HWKYRQSSDFMPDGYLMPSYQLTTPLTLAFFAFVFISLFLQKSTYIGAIGASIWILVF
                     GCYSQLKCKKALKG"
     gene            17058..18518
                     /locus_tag="TV191_001006"
     CDS             17058..18518
                     /locus_tag="TV191_001006"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEL1507533.1"
                     /translation="MYRDDSLTLHTDLYQLNMMQVYFEQGIHNRNAVFEVYFRREPFN
                     NGYAVFAGLQRIVEYLEQLTFSETDLAYLKELGYSPAFLTYLRELRLELTIRSAQEGD
                     LVFANEPIVQVEGPLGQCQLVETALLNIVNFQTLIATKAARIRSVIEDEPLLEFGTRR
                     AQEMDAAVWGTRAAIIGGADATSNVRAGKRFDIPVSGTHAHALVQAYGNDYDAFKAYA
                     SVHKDCIFLVDTYDTLRVGVPTAIRVAKELGDKINFLGVRLDSGDLAYLSKRVRQQLD
                     AAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVSIE
                     QADGTMRDTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITFTGVNVNDLEEIHM
                     FHPTYTYINKTVRDFDAVPLLVDIFDKGKLVYQLPSLKDIKAYARKEFDKLWDEYKRV
                     LNPQHYPVDLALDVWQNKMHLIDKIRKEACKRSDLI"
     gene            18515..19339
                     /gene="nadE"
                     /locus_tag="TV191_001007"
     CDS             18515..19339
                     /gene="nadE"
                     /locus_tag="TV191_001007"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEL1507534.1"
                     /translation="MTLQEDIIRQLEVKAVIDPKQEIRQSVDFLKAYLLKHPFLKTYV
                     LGISGGQDSSLAGKLAQMAIEELRAETGDEQYQFIAVRLPYGVQADEADAQKALAFIQ
                     PDQALTVNIKEAVDGQLRALEAAGLEISDFNKGNIKARQRMISQYAIAGQTAGAVIGT
                     DHAAENVTGFFTKFGDGGADILPLFRLTKRQGKALLKVLKADPSLYEKVPTADLEDKK
                     PGLADEVALGVTYQEIDDYLEGHTISAEAQARIEDWWHKGQHKRHLPITIFDDFWK"
BASE COUNT         5553 a         3712 c         4715 g         5932 t
ORIGIN      
        1 ttgctgtaga agtgaaataa taatctggtg atactccgga ggaagtaaag gcataatcag
       61 ctgttgggtg atacgtcacg ttgccttttt gaaaatcaag agcgataagt cttcctattg
      121 cccccaaagg tggcccctcc tcggaaaaga ccagataacg atttgaaagc tctgctcgtt
      181 taaccacttg attgatctga cctttgacca cttcgagctt agcgtcagaa attttttgcg
      241 gctgctcatt tgtcaattga taaccttcaa tattgtggta accgactata tagaaatctg
      301 cgtctggcct tacggtaaat gattggtctg atgaaccgaa tcgtttttga gcgacgaaaa
      361 atataccaca aaagacaatt aaaaatgaca tagctatctt gcttcttttt gatagtttaa
      421 ccatagtgat ttattcctat aactaattaa ttgctttaga tgactgacag gctctgtcgt
      481 cctaagcccc caaactaatt gagaacaatt gagtcttggg attccaaaaa tttaaatgat
      541 acggttttcc tacttgattt ccagcctatt gatttgcgtt ccagtcttgt tgaacactgg
      601 tagcctttgc gccaatgtgc cagacagtat gcctgtgact tgttcttgct acttctgaaa
      661 cgtgttcttt ctgtcaggta ttgcgcttta cagcaaggtc tggcccttag gtagtaaata
      721 tagctgtttg cgctttcatt ttatcgtatt gtgcgttttt gtcaatagct ttagtgttgg
      781 tatatggtca ttaaaaatga caggacaatg caggaggatc agacttaaac ttacaatagg
      841 ataaagcgta gcgtggtatg tggtgtcaca aaggaaatcc tgcttggagt ggctatcagg
      901 tggattttta tatcttaggt gaatgggtag ccagtgatcc ttttttttat caagctgata
      961 ggctgattga ttttggcttc aatctaacag tcctctgggc tgttttttat gctataatcc
     1021 taatatgatg aaacgacaat ttgaagatgt aaagcgtatt gtaattaaaa ttggaaccag
     1081 ctcgctggtg cttgctaatg ggaagattaa cttagaaaag atcgaccatt tagcctttgt
     1141 gatttcaagc ttaatgaata agggaaaaga ggttattttg gtttcctctg gcgccatggg
     1201 ctttgggctt gacctgttga aaatggccaa aagaccaagt cagcttgcca agcagcaggc
     1261 tgtttcaagt gtggggcagg ttgctatgat gagcctttat tcgcaaattt ttgcccacta
     1321 tcagacgaca gtgtctcaga ttttgctgac acgtgatgtg gttgtttttc cagaaagtct
     1381 ggcaaatgtc accaatgcct ttgaaagcct gattagttta gggattgtcc ccattgtcaa
     1441 cgaaaatgat gctgttagtg ttgatgagat ggatcattca acaaaatttg gagacaatga
     1501 ccgcttatca gctatcgtag ctcgtattac aagggctgat ttgctgatta tgctatcaga
     1561 cattgatggt ttgtttgata agaatccaac catctatgag gacgcgcgct tgaggagtca
     1621 tgtgacagag attacagagg atattatagc ctcagcaggc ggtgcaggca gcagatttgg
     1681 aactggtggt atgctaagta agatccaatc agcccagatg atgtttgagc atcaggggca
     1741 aatgattttg atgaatggtg ccaaccctag agacatttta agggtcttgg agggagaaaa
     1801 gctaggcact tggtttaaac agatagaaag aggtgacgcg tgatgacaat agaacagcta
     1861 ggacaaaggg ctaaggcagc tagtagggcc ttggtatcct tgacaacgaa ggataaaaat
     1921 caatttcttg cctttttggc tgaggaatta gtggcccaga cggatatgat tttgacagaa
     1981 aatgccaagg atctggctaa ggcggctgag catgggattt cagagattct gtgcgatcgc
     2041 ttacgcctga cagcagatcg tatccatgcg atggctcagg gcgtcagaca ggtggcagac
     2101 ttggctgatc ccattggcga agtgattaag ggctatacaa atctggacgg cctgaaaata
     2161 acccaaaagc gtgtgccttt aggtgttatt gcgatgattt ttgaaagccg ccctaatgtt
     2221 tctgttgacg cctttagctt ggcctttaag accaataatg ccattattct tagaggtggc
     2281 aaagatgctc tctactctaa tatggccttg gtcaggctta tcagaaatgc cttagaggca
     2341 tcagctatta cgccagatgc tgttttgctg gttgaggata cctctcatgc tgtagctgag
     2401 gaattgatgc aggcaacgga ttatattgat gtcttgattc ctcgtggggg tgccagatta
     2461 attcaaacgg tcaaggaaaa ggctaaggtg ccagtcattg agacgggggt tggcaatgtt
     2521 cacatttatg ttgatgaagc agccgatcta gagatggctg ttaaggttgt gattaatgct
     2581 aagacgcaaa gaccaagcgt ctgcaatgct gcagaaagcc tgattattca tgagaaggta
     2641 ggagcgacct ttattcccat gcttgaagca gccatcagca aggttcagca ggtggaatgg
     2701 cgagcagatg agcaggcaaa agccttgttt agcaaggctg tattagccac agaggaagat
     2761 tatgcggctg aatttttgga ttatatcatg tctgttcatc tggtttcctc tcttgatgaa
     2821 gctatttctt ggattaatca gtataccagt catcattcag aagccatcat cacagctaat
     2881 atcaatgctg cagagcgttt tcaggatctg gttgactcgg cagctgttta tgtgaatgcc
     2941 tcgacacgct ttacagatgg ctttgtcttt ggtctaggag cagaaattgg catttccaca
     3001 caaaaaatgc atgctcgtgg cccgatggga cttgaggcct tgaccagcag taaatacctg
     3061 atcaatggaa atggccagat tcggagctag ctgctaagga ggtaggctta tgacaaggga
     3121 tctaaagaag caagaaacca tacgagacct aaagacatta gcttttaagc ttgagtctgt
     3181 cattgaggca ttgaaagagc ttaagaggtg gggatttttt gatttgttcg acaatgggat
     3241 actaacaagc tgggtaaaaa ggcaaaaaat cagtgctatt aatgagagcc taggggacgt
     3301 gagaaatctg gtctgtaggt atcaaaagga gctgaaggtt agtgagttgc gcttgccttc
     3361 tagcttatct catacaagac aggataagat ctttgatatt tggctagata attcggtgac
     3421 agattttcgg gtgttaaagg agaccaagca ggtgctcgaa tcggctgagc tgctgtatga
     3481 ggctgtgcag caagctctta gtcatcttga tgtcaaggat agctaagcca aaaaaagtaa
     3541 gataaagagg gactttctta ggccttgaaa gcccttttct cttacttttt gatttataaa
     3601 ccctttgaag tatggtacaa ttagagctat gacaaacgaa tttcatcatg taactgtact
     3661 tcttcatgaa gctgttgata tgctggatat taagccagat ggtatttatg tagatgcgac
     3721 ccttggtggc tctgggcact cagcttattt gctgtctctg cttggtgata aggggcactt
     3781 gtattgcttt gatcaggacc aaaaggctat tgatcacgcg caggagcagc tcaagcccta
     3841 tattgacaag ggacaggtga cctttattaa ggacaatttt agacacctta aggcacgctt
     3901 gctggagcat ggggttacag agattgatgg gattttgtat gatttagggg tttctagtcc
     3961 gcagttagat gagagagagc gtggcttttc ttacaagcag gacgctccct tggacatgcg
     4021 aatggatagc caggcggctt tgacagccta tgaggttgtc aatacctatg atttcaatga
     4081 cttagttcgg atctttttta aatatggtga ggataagttc tcaaagcaga ttgctcgtaa
     4141 gattgagcag gcgagagcca ttaagccaat cagcaccacc acagagctgg cagcattgat
     4201 caaatcagct aagccagcca aggagctcaa gaaaaaagga cacccagcca agcaaatctt
     4261 tcaggctatt cgtattgagg tcaatgatga gcttggtgct gctgatgcgt ctatccagcg
     4321 ggcgatagag ctgctagccc ttgatggccg tatctcagtg attacctttc attctttgga
     4381 ggatcgtctg acaaagcact tgtttaaaga agcaagcaca gctgatgctc caaagggact
     4441 tccctttata cctgatgagc tcaagcctaa gcttgaattg gtttcgcgta agccgatttt
     4501 accaagtcaa aaggagctaa tggctaacaa tagggcacat tcagccaagc tacgagtcgc
     4561 aagaaaagtt cggaaataga ttatggttaa tgaaaaaaga actcaggcag tttcaaaagc
     4621 cttgcaaaaa agaattagaa ctttctcgag ggttgagaag gctttttatg ctacgcttat
     4681 cctgacagca gtaacgatgg ctgtaagcat tatttacctg caaagccgta aattgcagct
     4741 ccagcagcat atcactcagc tcaataggca gatctcagat aaaaggacag agcttaacaa
     4801 tgccaagcaa gaggttaatg agctgtcgcg acgtgaccgc attgttgata ttgctggcaa
     4861 agcagggctt agtaaccgaa atgataacat taagaaggtc gagtaagcta tgacaaaatg
     4921 gcaaagatat tttttagatt atgtggttcg tgatcgaaag acacctgttc agaaccgctt
     4981 gagggtgggg caaaacatga tgctcttaac catctttatt ttcttcatct ttatgattaa
     5041 ttttatgatc attatcggga cggatcagaa attcggtgtt aagctatcag atggagccaa
     5101 aaaggtttat caagagacgg tttctgttca ggccaagcga ggcacgattt atgatcgcaa
     5161 tggcacagct atcgctgtgg actcgacgac ctatagcatt tatgccattc ttgataagtc
     5221 ctttgtgtca gcgactggcg agaagctttt tgttcaaccg tctcagtatg acaaggttgc
     5281 tcaaatcctc aaggagcagc tgggtatgga ggaaaaggac gttattaagc agcttaagca
     5341 aaaaggtctt tttcaggttt cctttggtcc gtctggctca ggtatttctt atagcacgat
     5401 gacaacgatc caaaaggcta tggaggcagc taaaatcaag gggatcgcat tttcagcaag
     5461 tcctagccgt atgtatccaa atgggacctt tgcttcagag ctgattggtc ttgcttcact
     5521 tgaggaaaac aaggaggacg gtaccaagag cctagttgga aagatgggca tggaggcggc
     5581 ctttgatagc atcttatctg gggaagatgg aatcatcact tatcaaaagg atagaaacgg
     5641 taataccctg cttggaacag gaaagacagt gaaaaagcca gttgatggta aggacgttta
     5701 taccaccctg tcagagccta ttcaaacctt tctagaaacg caaatggacg tctttcagtc
     5761 gaaggcgcaa ggagagcttg ctagtgctac tctagtaaat gctaagactg gtgaaatctt
     5821 agcgactact caaagaccaa cctataatgc agacaccttg gaggggctaa acagcaaaag
     5881 ctatagctgg caaaatattc tccatcaggg gcagtttgag cccggctcaa ccatgaaggt
     5941 tatgactctg gcagctgcta ttgatgagaa ggtctttaat cctgatgaga cctttagcaa
     6001 tgcgaatggc ttaaccattg ctgatgctac cattcaggat tgggcgatta acgaagggat
     6061 ttctacaggg cagtacatga cctatgctca aggcttttcg ttttcaagta acgttggcat
     6121 gaccaagcta gagcaaaaaa tgggaaatga caaatggatg aactacctaa ctaaattccg
     6181 ttttggattc cggacacgct ttggcttgga aaatgaagac ccaggtattt tcccttctga
     6241 taatattgtt acccaagcaa tgagcgcttt tggtcagggg atttcggtga cgcaaattca
     6301 aatgcttaga gcctttacag ccatctctaa tgacggtgtg atgctagagc ctcaatttgt
     6361 tagtcgcatt tatgacccaa atacagatac ttaccgggtg tcagacaagg agattgtcgg
     6421 aaagccggtg tcccaaaagg ctgccagtga aacacgaaaa tacatgatta acgttgggac
     6481 tgacccacaa tttggaaccc ttcatttgaa atcatcaggt ccagtggtta aggttggtca
     6541 attaccagtt gctgtcaagt cagggactgc gcagattgcg actaaggacg gtacaggtta
     6601 tttagatggt ggcttgacaa actatattta ttcggtggtt gctatggtgc cagctgatga
     6661 gcctgatttt ctgatgtatg tcacactgaa gcacccagag cattgggcaa tggtgttttg
     6721 gcaggatatt atcaaccctg ttttagagga agcctatttg atgaaggata ctttagacaa
     6781 gccggttgct gtagatacca gtcacgaggc tacttatcag ttgcctgata ttgttggcca
     6841 agatacagga aaatcagctg atgagctacg cagaaatctg gttcacccta ttgtccttgg
     6901 caatggcagc aagattaaaa aggtatctaa aaaggcaggg accaatctag ctgctaacca
     6961 acagcttctg attttatcaa atcattttga tgagatgcct gatatgtacg gctggactaa
     7021 ggctaatgtg gctacctttg ctaaatggac tggcattgat atcaagtaca agggatcaag
     7081 ctcgggacgt gtcgttaaac agagcgttga tgtcggaaaa gcgctcaaaa aagtcaaaaa
     7141 aattaccata actttaggag attaacatgt ttttaaccat tctagcaggt ctgatagcct
     7201 ttgctgtgac tgcccttgcc atgcctcact ttataaggct ttaccagttg aaaaaaattg
     7261 gggggcagca gatgcatgag gacgttaagc agcatttggc taaggctgga acacctacaa
     7321 tgggaggaac agtttttctt cttgttgcta caagcttatc ctttgtgttt gctttagtct
     7381 attttcgaga tggacaaagc ctaggcttga tttcggggat cttgttgatt gtattgattt
     7441 acgggatcat aggcttttta gatgatttct taaagatctt caagcaggtt aatgaaggcc
     7501 ttactgccaa gcaaaaattc acgtttcaga ttgttggagg cctggtcttt tatgtgatac
     7561 acgtcatgcc aagtggtatt gatgcgatta atgtctttgg ttatcattgg catttgggct
     7621 ttttatacct atgctttgtt cttttttggg tggttggctt ttcaaatgcg gtcaacctga
     7681 cagacggtat tgatggtctg gcctcggtat ctgttgtgat tagcctgctg gcctatggtg
     7741 ttatcgctta tgctcaggga caatttgatg ttttgctctt gataggtatc atggttggtg
     7801 ccttgctggc ctttttcttg tttaaccata agccggccaa aatttttatg ggtgatgttg
     7861 gaagcttagc cttaggagca atgctagcag cgatttctat tgcgcttcgt caggaatgga
     7921 ccttgctggt tattgggatt gtctatgttc ttgagacaag ctcagtcatg cttcaggtta
     7981 cttactttaa atacaccaag aaaaaatatg gtgaaggccg tcggattttt aggatgactc
     8041 cttttcatca tcatctggaa ttaggcggct tgtccggtaa agcagccaag tggtctgaat
     8101 ggaaggttga tgccttccta tgggctcttg gtcttgtagc cagtctcatt gttttagcga
     8161 ttctttattt gtaagcggct ggggcagtgc ttgaggcacc gccttttgct catctcaagc
     8221 actaatagta ttatcagaaa gaaaacgagg taaataatgt catttcacga ttatcacttt
     8281 aagcattata ttcaagaggc cctagatgag cttggctttg tagagccaac agaggttcag
     8341 cagcgtctta tcccgattgt cagtacagga cgagacttag tgggtgagtc aaagacaggc
     8401 tcaggaaaga cgcatacctt tttgctgcct atttttgaaa agctcaagga ggaaaaagaa
     8461 gaggttcaag ctgtgattac agcacctagc cgggaactag caacacagat ttttgaggcc
     8521 agcaggcaaa ttgctaagca ttctaagcag gagattcgta ttgctaatta cgttggaggg
     8581 acagacaagc agcgtcagct tgacaagtta aagcttagtc agccccagct tgtcattgga
     8641 acgccaggtc gtatctatga tctagtcaag tcaggagatt tagccattca taaggcctct
     8701 acctttgttg ttgatgaggc tgatatgaca atggatatgg gctttttaag cactgtggat
     8761 aagattgctt cagcactgcc aaagactatc caaatacttg tattttcagc aaccattcca
     8821 caaaagctac agcccttttt aaggaagtat ttgaccaatc ctgtcattga acagatcaag
     8881 acagaaaccg ttattgcaga tacgattgac aactggctgt tatcaaccaa gggacgcgat
     8941 aaaaatgagc aaattttggc gactctaaag gctatccagc cttatctggc catgcttttt
     9001 gtcaatacca aggagagagc tgatgactta catgcctttt tagcagctaa tggtatgaag
     9061 gcagccaagc ttcatggagg tattcctcct agagagcgca agcgtatcat gaatcaagtc
     9121 aaaaacctgg catttgaata cattgtggca acggatttgg cggcgcgtgg tattgatatt
     9181 gagggggtta gtcatgtgat taacgacgcc attcctcaag acctatcctt ttttgtgcat
     9241 cgtgtggggc ggacaggtag aaacggcctg ccagggacag ccattacctt ttatcagcca
     9301 agtgatgatt ctgatatcaa ggagctggaa aagctaggca ttacctttat accaaaggtt
     9361 ttaaaaaatg gtgagtttca ggatacttac gatcgtgatc gtcgccagaa tcgtgaaaaa
     9421 gcttatcaga aattagacac tgaaatgatt ggcctggtta agaaaaaaaa gaaaaaaatt
     9481 aaaccgggct ataaaaagaa aattcaatgg gcagttgatg aaaagcggcg caagcagcga
     9541 cgagcagaaa aacgtgccaa gggacgagca gagcgtcagt ccagaaagca aagcttttaa
     9601 gacaggtgct tggtaaagat catccgttca agaaaaatta gatcaaaaag tttttagcga
     9661 tcattctaag ctgatatgaa cagaatcctt gacagagctg agtcaaggaa ctgtgattag
     9721 gtcccaaagc tgtttaggga ttgtttttaa aggcttcaac tctgttcagt gtcccatgtc
     9781 aaatggtcct gtcgttgcgt gcaaggattt caatctacgc tcccgcaaaa ggtgtgataa
     9841 aagtattgtt acatttgaaa ttgtcgaacc tacttcaatt gttacagcaa ctatctttga
     9901 agcgtggcaa ctaaaaccag ctattaacaa ctaaagccgc acctttggct gtcagaatag
     9961 tgattgaaat taacgggttg atacgctttg acacaccagc cttaaattac ttcctctgtg
    10021 ggagtgtaga ttaaggtgta ttaatgtttg aggaggagct tgctcctctt ttttgcttgt
    10081 tcagctcaat gtctctctga aggctatggt tttggttaga tggtaagcac taaaaaacct
    10141 tataagcatt gagcatgggt ctgaccattt caatgcctat aaggcctatg attagctaat
    10201 attagctatt atatgaagca gtcggttaac taagctgcgg ttacttatta gcctcatacc
    10261 aggctagcac cgcttcttga agctctccga tgctggtaga ttctggacta aagatattga
    10321 gctctgagac gccgtcaata ccagtcttaa caccgccatc tccctcataa ccttctagga
    10381 tactccaata ccctccgtca ggatcggcaa taatccttga atttttagtc aggtactcac
    10441 cctctccagc gaaaatataa ttcatgagga aggtctctgt cagaatgcct tctcttttag
    10501 cctgagctag gtaagtaatc attttattaa tggttacatt gtcatgatac ttaattactg
    10561 gttgttttct tgactggata agacgtgcca tctccttatg atttaaatca gaataatcag
    10621 tggagtagat aaatcttgtt gataagctta aaacagctac tgttaacaaa gtaaccgata
    10681 ctattgcctt tttcatagaa aacctcctta tacttaatta taatgtaaaa agattaatat
    10741 agcaacagtt aaagtttaat aataaaaatt tattttaaac tatttactcg ttttctaatg
    10801 ttaaacagaa tgaaagctag ttttctaggc ttcataaggc agataggtca actttttttc
    10861 tgatcgttaa ctgacagcct agtagtagag ctggatagga atgaccagtt aagaagggtg
    10921 ctactggttg aatgacacaa acagttcttt ttcttcttgt agaggtgact actagctttt
    10981 acatcagtca gttgaaagct tgaggtgttg attttggctt aggcagcctg ctaatagcta
    11041 aagcttgtct gttgtggtta atccatgatc aggtaaatga agaatgtgct gttttaattg
    11101 cttgtttgat actattttct tattgccttg atagagaaat gatattattc aaatttatca
    11161 ttttttgtta aaatggctac tgtataagag ataggagtat ggtatgacaa aacaattaca
    11221 gcgagcactc ttttttttgc tagcaagtct aggactcttg gcagtcgtga ctagccatga
    11281 ggtcacagct cgtcaaaaag aggtgatcag agtagcaaca gatgctgcca ctaagccctt
    11341 tacctatagg aagaagcata gcgttacagg ctatgatatt gaggttctaa aaagggtttt
    11401 taaaggctcc aaaaagtatc ggttaagcat agaggtggtt ccttttccat cgatcctggc
    11461 tggtattgat gcaggtcgtt atcagattgg ggccaataat tttggctata gtaaggaaag
    11521 agctgaaaag tatttgtttt caagccctat ttcggcctcg cattatgctc tggcaacaaa
    11581 gggtaagcag cagtataaaa gcttagctga tctttctgga aagaaaaccc aaggaatagc
    11641 tggctccaat tacatgctta tccttgaaaa atggaaccaa tcccatcctg accaaaagcc
    11701 tattcacctt acctatgctt ctgagtcaac cccatttact caaaggctgc agctgctgga
    11761 gaatggtcaa ctggactttc ttttctatga cgctatttct ctaacaaccg tagctgagga
    11821 gcaaggcttt gatgtgcatg tgacaaagct caaggagcag gctgatactg ctaaggatgg
    11881 cttggaatat tatgtgtttg ccaatgatca aaagggtaag gctctacaga gctttgtcaa
    11941 caaaaggctg gctaagctta aaaaatcagg tcagctcaga aagctcagcc aagcattttt
    12001 gggaggagac tttatctcca aggtcaatta attgacaggg ctaaaagccc tcaagccctg
    12061 ggcaggcttc aatctttcgt tgacctagcc tttgaggcag ttagctgtgc cagctagcca
    12121 agcttttgac ctttttggcc tagtagctga ttgttagtct tgtaccagtg gctatattct
    12181 ttgagaatta gccacttgga ggctttgaga gttcggctca agttcaagct tggtagctcc
    12241 aagaggctac tgttaacggt atttcaaaga gtttttttcc tttgtttgag tcctatcctc
    12301 tgcgataggc ttttcttatc attatcatgc ggatttacta ttttacatga catctcaaga
    12361 atgttaaaat gaaaatattg agacaaacca gtataaaggg gcgatacatg acatctacgt
    12421 ttttaacaag tgggtgggct tggtatgaca agctcatctc gttgatccca gaagggaagc
    12481 tgtttagctg gcatgctgtt tttgatgcca ttccagatat tatcaggcgt ctgccaatca
    12541 cacttggttt gacgatagct ggtgctgcct tgggtctttt tttggccttg gtttttgcca
    12601 ttgtcaaaat caacagggtt cgcattcttt atccgattca agcggttttt gttagctttt
    12661 tgcgtggaac ccccatattg gttcagctaa tgctgagcta ctatggtatt cctctttttc
    12721 tgaaattctt aaatcaacgc tatggctttg attggaatat caacgctatt ccggcttcta
    12781 tctttgcgat taccgccttt gccttcaatg aagctgctta tacgagtgaa accattagag
    12841 ctgcgattca atctgttcac acaggcgaaa ttgaggctgc taagagccta ggaatgacct
    12901 ctgctcaggt ttatcgccga gttatcattc caaatgccgc tgttgtggca acaccgacct
    12961 tgattaatgg gttgataggc ctgacaaagg gaacctctct ggccttcaat gcaggtatcg
    13021 ttgaaatgtt tgcacaggca cagattctag ggggagcaga ttatcgttat tttgaacgtt
    13081 acatctcagt tgccttagtt tattggggca ttagtatttt gatagaacag gctggtcgcc
    13141 taattgaata taacatggct atcaaagcac caatcccaac aaataatagc aagataggag
    13201 aattgcgcta atgattaagg taactcattt aaccaagtcc ttctctggac aaaagatctt
    13261 agacgattta acggtgacga ttgaaaaagg gcaggttata gctctggttg gtgcatcagg
    13321 tgcaggaaaa tcaaccttcc ttagaagcat gaattatctt gaacagccag atacaggaag
    13381 tattacgatt gatgactttg cagttgactt tgaacacatc acaaaagaag acattctaac
    13441 gcttagacga aaattagcga tggtctttca gcaatttaac ctctttgaac gccgcacagc
    13501 gcttgacaat gtcaaggaag gattaaaaat agttaaaaaa ctgtctgacc aagaagcaac
    13561 agacatagct agagcagaat tagctaaggt tggcttgtct gatcgtgaaa accattaccc
    13621 tcgtcattta tctggcggtc aaaagcaaag ggttgctatt gcgcgtgctt tagccatgaa
    13681 gccagatgtg ctattattag atgagcctac ctcagccttg gatcctgagc tggttggaga
    13741 ggttgaacgg tctattattg atgctgccaa ggcaggtcaa acgatgattt tagtgagtca
    13801 tgatatggct tttgtttatc aggttgcaga tagggtgctt tttttagaca aggggaaaat
    13861 tcttgaagag ggagctcctg agcagatctt tagacaccct aaggaagcaa gaacaaagga
    13921 attttttgca aactatgcaa aaacgtatat ttaaaagccg gcttttgata taataaaaag
    13981 gtctaggtag gctaggcttt tcttgtatgt gcttaaaagc taagctgcca tgaaaaaagg
    14041 ttatggtaat caggtagata aagatgttag tagaaatttt tcgcttttat ttggaaggtc
    14101 tgttgttagc agctattacg atggtcatgc tttgtctttt gtggatttta tggcgtgctg
    14161 tgaccaaaaa ggataaaacc attctccaga gacaggcatt tttatatgag atgattatgg
    14221 ttgctatttt gacgattccg attttgtcct ttgcctttat gagcattctg gtggtattga
    14281 aggcgaaata attgcaatac gatgtagcta ttgttaaaat gatgacaaga ctattaagag
    14341 gagttaaccc atgtacgata cactcattat tggatcagga cctgctggta tgacagctgc
    14401 tttatatgca gcacgtagta acctacgagt tggcattatt gagcaggggg cacctggcgg
    14461 tcaaatgaat aacacatcag atattgaaaa ttatcctggc tatgatcaca tttcaggacc
    14521 agagctatcg ttaaagatgt atgagccgct tgaaaaattt aaggttgaaa acatttatgg
    14581 cattgttcaa agggttgagg attgtggtga ttataagcgt gtgtacacag aagatacgca
    14641 ctacgatact aaaacagtga ttgtcgcgac aggagcaaag catcgtcttt taggtgttgc
    14701 tggagaagag gagtacacca gtcgaggtgt ttcttattgt gcggtctgtg atggtgcttt
    14761 ctttcgcaat caggagttat tagttgtagg aggaggagat tcagcagttg aggaagccat
    14821 ctacctgacc cagttcgcta agaaagtaac gattgtgcat cgtcgtgatc agctgcgtgc
    14881 ccaaaagatc ttgcaggagc gtgcttttgc caacgaaaag cttgatttta tctgggattc
    14941 tgttgtcaag gagattcaag gaaacgatat taaggtctct aatgttgtga ttgaaaatgt
    15001 caaaacaggt caagtgacta gccatgactt tggtggtgtc tttatctatg tcggcttgat
    15061 tccggttact caaatggtat ctgagctagg cattaccaat caagagggct ggattgtgac
    15121 agacgatcaa atgaagacaa gtattcctgg tatttttgct gtcggtgatg ttcgtcaaaa
    15181 gcagctgcgt cagatcacaa cagcagttgg agatggtgcc attgccggtc aaggcgtcta
    15241 ccattacatt gaaagcctat catcttaaaa aggttaacgc taaaaaggct tggttggcct
    15301 ttttagtttg caagccttag agaaagttga acattttctg aaaaacagat ataatagtgg
    15361 tgttttttta attgaatgga gagtcaaatg tctacaaaag aagctaaaag cactaaagaa
    15421 cttgagaatg gcatggtaag ggggctgcaa aaccgacatg ttcagctcat tgcgatagca
    15481 ggcactattg gaacaggtct ctttctagga gctggtcgtt ctattgcctt aacgggtccg
    15541 tctattatct ttgtttacat gattacaggt gtctttatgt ttttgatgat gcgggctatt
    15601 ggtgagatgc tatactatga tccggatcag cataccttta tcaatttcat tacaaaatat
    15661 attgggccag gctggggcta tttttctggg ctttcttact ggatttccct gatctttatt
    15721 ggcatggcag agattacagc tgtcgcctcc tatgttcagt tttggtttcc tgcttggcca
    15781 tcttggctga ttcagctcgt ttttttggtg ttgcttagct ccatcaattt aattgctgtg
    15841 cgggtctttg gagagactga attttggttt gccatgatta agattgttgc gattttagcc
    15901 ttgattgcaa cagccgtttt tatggttcta acgggctttg aaacgcatgt cggtcatgcc
    15961 agccttgcca atattgtgga tcatttttca ctatttccga atgggaagtt gaaatttttc
    16021 atggcctttc agatggtttt ctttgcctat caggccatcg aatttgttgg tattacaacc
    16081 tcagagaccg caaatcctag aaaggtcttg cccaaggcca tccaagagat tccgatgcgg
    16141 attgtcattt tttacgttgg tgctttggtg tctattatgg cgattgtgcc ttggtatcag
    16201 ttgcctacgg acgagtctcc ctttgtgatg gtctttaagc tgattgggat taaatgggct
    16261 gctgctttaa ttaattttgt ggtcttaaca tcagcagcat cagccctaaa ttcgaccctg
    16321 tattcgacag gtcggcattt gtatcaaatc gctaatgaga ccccaaatgc tcttactaaa
    16381 gccttgagga ttaacaccct atctcgtcaa ggggtaccaa gtagggctat tattgcttct
    16441 gctgttgctg ttggggtgtc ggccttgatt aatatcctgc ccggtgttgc agatgccttt
    16501 tcgctgatta cggcctcatc atctggtgtt tatattgcga tttatgcttt gaccatgctt
    16561 gcgcattgga aatatcgtca gtccagtgac tttatgccag atggttattt gatgccaagt
    16621 tatcagctaa caacaccatt gaccctagcc ttttttgcct ttgtttttat ttcactgttt
    16681 ttacagaagt ccacctatat cggggcaatt ggtgctagca tttggattct agtctttggc
    16741 tgctacagtc agctcaagtg taaaaaagcg ttaaaaggct aaggtgtgag ttaaatagat
    16801 tgaagaaagg ggctattttg gtcaatttct tcaatctttt tttatgaatg ctatcaactg
    16861 aaactgcttt tgttaaaaag ccataagccc ttgtgctata gactttttag gaaggtactg
    16921 gcaaaaaata tgtcaggctt aatagcagct caaggcttct tttttagaaa gcttgagcag
    16981 aggattttag ttgaatctta caggtctatg ccaaaaatat ggtataataa taacaattat
    17041 gttaaggagt tacttatatg tacagagatg atagcttaac ccttcatact gatttatatc
    17101 aattaaatat gatgcaggtt tattttgagc agggcattca taatcgtaat gctgtctttg
    17161 aggtttattt tcgtagagag ccttttaaca atggctatgc agtttttgct ggtctacaac
    17221 gaatcgtaga ataccttgag caattgacct tttctgagac cgatttggct tatttgaagg
    17281 agctaggcta cagccctgct tttttgacct atctcagaga gcttcgttta gagctaacga
    17341 ttcgctcagc acaagaggga gacttggtct ttgccaatga gcctattgtt caggttgagg
    17401 gacctttagg tcaatgtcag ctagtagaaa cagctctttt gaatatcgtg aatttccaaa
    17461 ccttgattgc tacaaaggca gctcgtattc gctctgttat tgaagatgag ccacttttag
    17521 agtttgggac acgccgcgct caggagatgg acgctgctgt ttgggggaca cgtgctgcca
    17581 ttattggcgg agcagacgca actagtaacg ttcgtgccgg aaagcgtttt gacattcctg
    17641 tgtctggcac gcatgcacat gctctggtac aggcctatgg taatgattat gatgctttca
    17701 aggcctatgc cagtgtgcac aaggattgta ttttcttggt tgatacctat gataccttga
    17761 gggtaggtgt cccaacagct attcgtgtgg ccaaggaatt aggtgataag attaatttct
    17821 tgggtgttcg tctggattct ggtgaccttg cttacctatc taaaagggta cgccagcagc
    17881 tggatgctgc cggcttcaca gaggctaaga tttacgcttc caatgattta gatgaaaata
    17941 caattctcaa cctgaaaatg caaaaagcta aaattgacgt ttggggtgtt ggaacaaaat
    18001 tgattacagc ctatgatcaa ccagctctgg gagcggttta taagattgtt tcgatagagc
    18061 aggcagatgg taccatgcgc gatactatca agctatcaaa taatgcagaa aaggtatcaa
    18121 caccaggtaa aaagcaggtt tggcgaatta ccagccgcga aaagggcaag tcagaaggcg
    18181 attacatcac ctttacaggt gttaatgtca atgacctaga ggaaattcac atgttccacc
    18241 cgacttatac ctacattaat aaaaccgtca gagattttga tgctgttcct ttgctagtag
    18301 atatttttga taaaggaaag ctcgtttatc agctgccaag cttaaaagac atcaaggctt
    18361 atgctagaaa ggaatttgat aagctttggg acgaatataa gcgtgtcttg aatccgcagc
    18421 attaccctgt ggatcttgcg cttgatgttt ggcaaaataa gatgcatctt attgacaaaa
    18481 tccgcaagga agcctgtaaa aggagtgatt tgatatgaca ttacaagagg atatcattcg
    18541 tcagcttgag gtcaaagcag taattgatcc taagcaggag attcgccagt cggttgattt
    18601 tttaaaggct tatttgttaa agcacccttt tttaaagact tatgtcttag ggatttctgg
    18661 tggtcaggat tccagcttag ccggaaagct agctcagatg gcgattgaag agctgcgcgc
    18721 tgaaacaggt gatgagcagt accaatttat cgctgtccgc ttgccctatg gtgttcaggc
    18781 agatgaggca gatgcacaaa aagccttagc atttattcaa cctgatcaag ccttgacggt
    18841 taatattaaa gaggctgttg atggtcagct aagagcctta gaggcggcag ggcttgagat
    18901 ttctgacttt aataagggaa acattaaggc acgtcagcgt atgattagtc agtatgctat
    18961 cgctggtcaa acagctggtg ctgtcattgg gacagatcat gccgccgaaa atgttacggg
    19021 ctttttcact aagtttggtg atggcggagc ggatattcta cccctttttc gcttgactaa
    19081 gcggcagggt aaggccttgt taaaggtgct aaaggctgac cccagcctct atgagaaggt
    19141 gccaacagca gatctagagg ataagaagcc aggacttgca gatgaggtag cattaggtgt
    19201 tacttatcaa gagatagacg attacttaga ggggcatacg atttccgctg aagctcaggc
    19261 aaggattgaa gactggtggc ataaagggca gcacaagcgc catctgccaa ttactatttt
    19321 tgatgacttt tggaagtgat cctcaaacct acacaggcta tagataaacc aatgctattt
    19381 taaataggtg aggagggaca ggagcttcta ttaggcataa atccagtagc tgttgcctaa
    19441 gagcttccct cacccttagc cctatgaagg ctctgactta gggctttttt gtaaatggga
    19501 ttggggtagt tgttgatttg tccctatctt aaagcagcca agataaagga gaatgctcag
    19561 ctaactaaaa accagaggct ttaaggagaa gaagtctttg gttttagctt tgccatatgt
    19621 ttcagttaac tatcaggggc cccttgactt agccgatggt gttatatcaa gcacttttgc
    19681 tacagtggag acgattcttt ttgtggctaa ggcaagctaa tgattaaact gaagtcatag
    19741 ccagacacag ctagcttctt tgagttcatg ctgaggtgga catatgacat gtttaggtgc
    19801 tcaaagtcca gcaggttttg tcgtcttttg agatggcttt ttgtctggtt attggaaagc
    19861 tgctgcttag ctttaaaaaa ttaagttagc ctaatttttt tacttgaaga at
//
LOCUS       DARYXW010000035        18968 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.035, whole genome shotgun sequence.
ACCESSION   DARYXW010000035 DARYXW010000000
VERSION     DARYXW010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18968)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18968)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18968
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.035"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            <1..376
                     /locus_tag="TV191_001008"
     CDS             <1..376
                     /locus_tag="TV191_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="secretion protein"
                     /protein_id="HEL1507535.1"
                     /translation="QGGEKKDISYIEQEGDLSALFQSETDLSIKKKQQHRKETSQTTK
                     NHLFMTHIDSDNLVARYQPLLFNPEQRLAATDDQYGVLLAQKTIGITWQMLAILLVGA
                     VLTGYSLTRGRLSRQKHKRHHE"
     gene            692..933
                     /locus_tag="TV191_001009"
                     /pseudo
     CDS             692..933
                     /locus_tag="TV191_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678362.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein"
     gene            936..2093
                     /gene="essB"
                     /locus_tag="TV191_001010"
     CDS             936..2093
                     /gene="essB"
                     /locus_tag="TV191_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein EssB"
                     /protein_id="HEL1507536.1"
                     /translation="MEKKMKTIIRELLVEDVKGDAEVAYTLLASEHSLFVPSKLEQAF
                     DKLILEASIDDMYDWSALEAMIVEEKLRHLLNLSELFDQLLDSKFTYSFTPDNLVFNR
                     NAEPQLIFRGIKDQVPPYQPLEREVFVNTLKCMTIALLDKKTSYDALMGGKLPFYKGN
                     LFCEAVAKAEALQELQELLATKYHEEQKDNKEHFSRVANKTISRLKLTTICSSVLALL
                     SLAGVLYFLLFAMPYQEMVASLRMAFINQDYSKVITTAKHTDSKALSQGDKYIVAYSV
                     IMTEPLTDKQKEELSKISNQSNEDYLRYWVLIGQARIDDAMDIASYLDDPQLLMYGLT
                     KKIDDVQRDPNLTAEARTEQLNSYKSKLDELKKAYLTPKEEKAAGSSSDKE"
     gene            2105..6481
                     /gene="essC"
                     /locus_tag="TV191_001011"
     CDS             2105..6481
                     /gene="essC"
                     /locus_tag="TV191_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein EssC"
                     /protein_id="HEL1507537.1"
                     /translation="MTYLIYDDNAYHLYSDTVYQLGPSSGSDIFLPLLEDITLSVEGS
                     GVVLLEESYSTGKHCVALSDEVTVTLLILEAVTKYLLPDSSLYISGETTAALQLLDYP
                     SELVLTLDSDSASCYSPVSYYLNGKWTKGKQPLKASDELVFSDGLVLSFQDQLLSIQS
                     LYAIQTALLPLTEAVAEDRASEFHRSPRIILREPEGKVTIASVPTDDEGKRQSLLKLI
                     ITPLAMIVFTGLSYVFFRGGGMLMMMMGMSVITIGSSIHSYFSDKKWHKEAQQQKIKD
                     YLAYLDTKYVELAGYREEQIEALLYHYPNMTTILEMAQKTDRRIYEKAPYHFDFLTYR
                     LGLGDTPASFHIDYSDSELTKHHEKAKQRVQELIAYYQVTAQVPIQNAIASPIGYIGA
                     RKVVIEQVQQLMMQIATFHSYHDVQFIPIFREEELPLWNWSRWLPHTKLKVLNSRGFV
                     YSQRTRDQLLTSLYQLIKERQLDSEQDKGTEKQYTPHYIVLITDMSLMLDHNIMEYIN
                     EDLSHLGIHYIFVEEVIESLPEHVKTVIDYRGDKHAQLILQEGLYLNKAFTPLQPLSM
                     KDKEVFARHMAGINHVETLRNAIPNSVTFLEMYGVNKVEELNLLKRWKENEAYQTMAV
                     PLGVRGRDDILYLNLHEKAHGPHGLIAGTTGSGKSELVQSYILSLAVNYHPYEVAFLL
                     IDYKGGGMANLFADLPHVVGTITNLDGNQANRALVSIKAELKKRQRIFLENDVNHIDQ
                     YTKLFKEGRVKEPLPHLLIISDEFAELKANQPEFMDELVSTARIGRSLGVKLILATQK
                     PSGVVNDQIWSNAKFKIALKVQDVADSREVIKTPDAAEITQVGRAYLQVGNNEIYELF
                     QSAWSGADYNPKGRHTIQHETTVYEITANGQYQAINKDLSGLDKKREAKSMPTELDAV
                     VAEAQQLFEDLHIPKVASPWLPPLSEKIYASDLQSTHFKDYWGQTQDLQPVLIGYQDI
                     PERQEQSPLYFHMEKAGHILLVSSPGFGKSTFLQGFALDVMRKQTPAQAHFYLYDFGT
                     SGLIALSDFPHVADYFTLDETDKIMKSLRYLSEEIKTRKHALSKAKATNLNQYNQLSK
                     DTFPALFVIIDGFDSVMDAPFVDAVYNVLNVIARDGASLGMYLVVTLSRLNTMRLQLQ
                     SNFKTKLSLFLFDNSDLSSVVGRSNIPLDDIKGRAIMKRDDIIQFQIALPYSSEYYTD
                     YMAEVKREVEAMRAVYQGALPAAIPMLPEKVTPDMIAAMSDSAQDFVIGLEREDVVPA
                     GFTFKKSILMASDSPAFVANYYKLLDFQLQRLADQYRTVILDPSQRIARQFFEDSQRF
                     STALDVGDTLRAIVEDFKKRLAAPGQDYQKWLVVIPDIAATALAAGISEEDFKQLVTE
                     GSQYGVTLIFVGAYQDLVNNTYDNFVKLANQLIEQVFLGMRISDQSHTRYAYISNEPS
                     LRPTQGYILYPEGYDFIQLLEI"
     gene            6494..6823
                     /locus_tag="TV191_001012"
     CDS             6494..6823
                     /locus_tag="TV191_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
                     /protein_id="HEL1507538.1"
                     /translation="MSTVTMLPLGSIVILKGNTKKMMIIARVIAAPIKGEVYRFDYGA
                     CLYPEGMMGDSLIYFNHDDIFKIIQEGYADDDNALMLETIAQALATTDIPKGDVSALN
                     DRKTVED"
     gene            6827..7261
                     /locus_tag="TV191_001013"
     CDS             6827..7261
                     /locus_tag="TV191_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5082 family protein"
                     /protein_id="HEL1507539.1"
                     /translation="MGQVDYNHINQLQRQVDQHRASLSTATAEIASIDEKLERLRCAK
                     ASVGAIQGDVHQIKVSVMAKRDQPDWKGERKDRLMSSWEEFSHDYRHFQLELDAYYDA
                     ICDTITRLENQKYEQQGLIGWCQSMINSLGNEIEKLFHIREG"
     gene            7263..7547
                     /locus_tag="TV191_001014"
     CDS             7263..7547
                     /locus_tag="TV191_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04197 family type VII secretion effector"
                     /protein_id="HEL1507540.1"
                     /translation="MFGVIQLSEVVFGAHVLSLTAAKASLSDVKASFPSHQSSSKVLD
                     LYQSEFEALSQLVAAYARLLEKDIALIAEAGQELALTDKQLGQAIGFRLQ"
     gene            complement(7618..8920)
                     /locus_tag="TV191_001015"
                     /pseudo
     CDS             complement(7618..8920)
                     /locus_tag="TV191_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400088.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            9301..10011
                     /gene="ccdA2"
                     /locus_tag="TV191_001016"
     CDS             9301..10011
                     /gene="ccdA2"
                     /locus_tag="TV191_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEL1507541.1"
                     /translation="MELTMLLMVSVFIAGLLSFFSPCIFPVLPVYLGILLDSDDSRSI
                     TIFGKKLYWYGIVKTLAFISGLSTIFIILGYGAGLLGNILYAAWFRYLLGAFVILLGI
                     HQMEIVTIKKLQFQKSVAFQNKKDRNAVLNAFLLGITFSFGWTPCVGPVLSSVLALAA
                     SGGSGAWQGGFLMIIYTLGLGLPFLLLSFASGIVLKHFNKLKPHIPLLKKLGGLLIVI
                     MGLLLMTGNLNSLSGLFE"
     gene            10025..10675
                     /locus_tag="TV191_001017"
     CDS             10025..10675
                     /locus_tag="TV191_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002933805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HEL1507542.1"
                     /translation="MKKTTFLTTGLACLALLTACSAKDKMAMNDSKKDHMTRTDDKSK
                     MKKDQKDKMSDKKDMMSDDKHMSDADKASKNDGQMAPDFELKSIDGKTYRLSDFKGKK
                     VYLKFWASWCSICLSTLGDTQSLATMKDKDFEVLTIVSPGHQGEKSEADFKKWFEGTD
                     FKDLPVLLDPDGKLLEAYGVRSYPTEIFVGSDGVLAKKHIGYAKKSEIEKTLKEIK"
     gene            10693..11805
                     /gene="msrB"
                     /locus_tag="TV191_001018"
     CDS             10693..11805
                     /gene="msrB"
                     /locus_tag="TV191_001018"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEL1507543.1"
                     /translation="MEHKWKLLLLVFGALVFLGGVLMVFQRGYATSYHNNQVKLPAKG
                     TSQLKKTANAKLPEKKKEIYLAGGCFWGVEEYFSNVDGVLDAVSGYANGRGDTTSYQL
                     LHQTGHAETVQVVYDANRISLKELLLHYFRIIDPTSLNKQGNDRGSQYRTGIYYTDPS
                     DLTTIDMVFQEKASDYKKKIVVEKAPLKSFTKAEEYHQDYLKKNPNGYCHINVNEASY
                     PVIDKTKYPKPSKEEIKKKLSKDEYRVTQNNETEKAFSNRYWDSFEAGIYVDVVTGEP
                     LFSSKDKFESGCGWPSFSRPISPDVLRYKTDKSFNMNRTEVRSRSGNSHLGHVFTDGP
                     KDQGGLRYCINSLSIRFIPKAEMEAKGYGYLLTAVD"
     gene            12073..12813
                     /locus_tag="TV191_001019"
     CDS             12073..12813
                     /locus_tag="TV191_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEL1507544.1"
                     /translation="MYSLLIVEDEYLVRQGIRSLVDFDQFAIDRIAEAENGQVAWELF
                     QENPYDIVLTDINMPKLNGIQLAELIKARAPKTHLVFLTGYDDFNYALSALKLGADDY
                     LLKPFSKSDVEEMLKKLKQKLEKLKKTEALQKLVDKPQQEGSEIKLAIQERLADSSLT
                     LKSLSSQLGFSPNYLSVLIKKDLGLPFQDYLIQERLKKAKLLLLTTDLKVYEIAEQVG
                     FEDINYFSQRFKQLVGMTPRQYKKGEGQ"
     gene            12810..14528
                     /locus_tag="TV191_001020"
     CDS             12810..14528
                     /locus_tag="TV191_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1507545.1"
                     /translation="MKRYPLLVQLVSYFFLIVISLITILGVIYYQTSSHNIRQLIERE
                     TRQSIRQSSQFIDAYIKPLKETTSALASHAEIQSFAKAANSSHQEQVLALMTTVLSTN
                     SDLRSAVLVTKDGRMVTTNPKLIMTTSHDMMAEPWYKSAIDRKAMPVLTPARQLSSHS
                     KKDWVVSVTQEVVDETGNNLGVLRLDIGYNTIKSSLDQLQLGRRGFAFIVNDKHEFVY
                     HPKNTVYSSEREMAAMKPYLAVADGYTKPKDYFVYQRVIPDSQWTLIGVASLDQLYHV
                     QRQIFWSFLGTGLLATVICGLGTVFVLRSWIGPIRRLQALILAIQKGNRQLRAEEIGS
                     PELADLARQFNAMLDQIDSLMISVADKEKAIGQYRLQALASQINPHFLYNTLDTIIWM
                     AEFNDSQRVVDVTKSLAKYFRLALNQGNELISLADELDHARQYLFIQKQRYGDKLHYE
                     IKGLEKYQDFMIPKLILQPLVENAIYHGIKEVDRPGMIRVTVLEADRHVILSVWDNGK
                     GISLADDSSQALLECGGVGLKNVDQRLKLQYGHLYRMAITSEQAVFTEIKLYLPKPLD
                     GLNELP"
     gene            14567..15655
                     /locus_tag="TV191_001021"
     CDS             14567..15655
                     /locus_tag="TV191_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEL1507546.1"
                     /translation="MSLESDYFKRKSPVFEALIPYGFTQEGDTYCYQESFMEGDFKAL
                     ITIKSSGQLSARVIDTDLGEDYLPLRNDRQQGVYVGQVRQAYLELLGRLSAACFRSTP
                     FQTRQANQVATSISQQWNDPLDYPFEKFPNIATYRVSGKWYAMVLPLLADKLGQVPKV
                     LQGQMVEVLTVRIAPNQLTHLLQQRGVYPAYHMSKKTWISLLLDGTLADDQLWELVTK
                     SRQLANPNGLANPDGPDYWVIPANLSYYDIDAEFAANPDILWTQKASIKAGDYVFIYI
                     TAPTRSIRYACQVLRSDIPNQGYRKNAKIKTLMSLRLLHCYEDGLISLDLMKQYGVNA
                     VRGPRRLSPQLVAFLKEKEYFKDVKQKE"
     gene            15670..16374
                     /locus_tag="TV191_001022"
     CDS             15670..16374
                     /locus_tag="TV191_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HEL1507547.1"
                     /translation="MTQFIADQSFWELFPDAKLGVLLLRNYDNQEDSPQEVKQLLADS
                     HDIAKQYLTEESFSDNEIIQVYRQAYQRFKTKKGARSSIEALLKRVANGQVLSSINPL
                     VDIYNTASLRFGLPVGAEDSDCFVGDLRLTLTEGGDEFYLIGDSKNSPTLPNELCYKD
                     DAGAVCRCLNWRDGERTMITDRTKNAFLVIEALDSKTQARLQDALKFIEDKAKCYLKA
                     ETALYTLDQASPSITF"
     gene            16634..17122
                     /locus_tag="TV191_001023"
     CDS             16634..17122
                     /locus_tag="TV191_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003032586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HEL1507548.1"
                     /translation="MELFDKVDDTLKALAIDYQLVEHEPALTTEQADQFIEGIEGVRT
                     KTMFLTTRKKNHFYLIIMDDTKRLDMNRFKELVGEKQIKMASAECLLAKMQLPPGVVS
                     PFGLLNNEDKDIQVYVDKAIAHEARMSFHPNTNDKTIFIQTDDLFKFLAAIGYAVNIV
                     DL"
     gene            complement(17632..18105)
                     /locus_tag="TV191_001024"
     CDS             complement(17632..18105)
                     /locus_tag="TV191_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEL1507549.1"
                     /translation="MNKKETRHQLIRSLISETTIHTQQELQERLRKNGISITQATLSR
                     DMKELNLVKVTTGNDTHYEALAISQTRWEHRLRFYMEDALVMLRVVQHQIILKTLPGL
                     AQSFGSILDAMQISEIVATICGDDTCLIICEDNEQAKACFEILSHYTPPFFFSNK"
     gene            18246..18926
                     /locus_tag="TV191_001025"
     CDS             18246..18926
                     /locus_tag="TV191_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEL1507550.1"
                     /translation="MIRREDYQYLRKLDDFCHFSIEQFDKIVGQMEFRQAKKDHMLFF
                     EGDKRDRLFLVTSGYFKIEQSDRTGTFTYTDFIRHGTIFPYGGLFTDDYYHFSVVAMT
                     DVTYFYFPTDLFEDYSLHNQQQMKHLYSKMSSLLELHELKVRNLITSSASSRVIQSLA
                     ILLVEMGKDSDTLPFQLTTTDIAQMSGTTRETVSHVFRDLKKEGLIAVKGKYLTYLDK
                     NYFLQYTT"
BASE COUNT         5446 a         3581 c         4397 g         5544 t
ORIGIN      
        1 tcaggggggt gagaaaaaag acattagcta catcgagcaa gagggcgatc tgtctgccct
       61 atttcaatca gagacagact taagcattaa aaagaaacag cagcatcgaa aagaaactag
      121 tcagacgacc aagaatcacc tatttatgac tcatattgat agtgacaacc ttgttgcaag
      181 gtatcagcca ctcttattta acccagagca gcgtctggca gcaacagatg accagtatgg
      241 tgttttgctc gctcaaaaaa ctatcggcat cacttggcaa atgctggcca tacttcttgt
      301 gggagctgta ctgactggct attctctgac tagagggcga ttatcaaggc aaaaacacaa
      361 aagacatcac gagtagaatc gtctgtcaag agtatctact cactgaaaat agagggctag
      421 cttaggagac ttcctaatgc tgcatttata agaaaaggct ctcagctgtt ttgacagtat
      481 tgggcaaggc cttagggcct gtagcaaata tgaagagcag ctttgatcag caggtagcaa
      541 gtcagtcaat acaaatgctt gaaagcctac ctgctgagaa aagtgtgtgt tctacgatac
      601 tttagtgatg tgaatcacct caagaggctt tagctagctt ggcaggtgat gtcaggtgac
      661 atggaaactt atcaggaaag ggctaatttt tatggagaat tatattagta tcagtcttga
      721 ttgctcgcat ttttttcaca ggaatttgat ttgcgggtac caaggacaat gacctttaag
      781 gagctattac aaatcgtatc agatgcttat ggtttgggat ttcaggtggt aaatcccagt
      841 gctagaaatg agcaaggtgg tcagctgatg acaagcacca gtcgcatgga taccctaaaa
      901 aatggtgcac tgttagtatt ggaaaattta taaacatgga gaaaaagatg aaaacaataa
      961 tacgtgagct attggttgag gatgttaaag gagatgctga ggttgcttat accttactag
     1021 cttctgagca ttctcttttt gttccttcca agttagaaca ggctttcgac aagctgattc
     1081 tagaggctag cattgatgac atgtatgact ggtcagccct agaggcgatg attgttgagg
     1141 aaaagctaag gcatttgcta aatcttagtg agctgtttga tcagctcttg gactcaaagt
     1201 tcacctacag ctttacacca gataatctgg tctttaaccg taatgcagag ccacagttga
     1261 tttttcgggg aatcaaggat caggttcctc cttaccagcc gcttgagcgt gaggtctttg
     1321 tgaatacact gaaatgtatg acaattgcct tgcttgataa aaagaccagc tatgacgctc
     1381 tgatgggtgg caagcttccc ttttacaaag gcaatctttt ttgcgaagca gtggccaagg
     1441 ctgaggcgct gcaggagttg caggagcttt tagcgacaaa gtaccatgag gagcaaaaag
     1501 acaataaaga gcatttttct cgtgttgcta acaagacgat atcgcgcttg aaattgacca
     1561 ccatttgttc atcagtgctt gctttgttgt ctttggcggg cgttctttat tttctattgt
     1621 ttgctatgcc ttatcaggaa atggttgcta gtctgcgtat ggcttttatt aatcaagact
     1681 attctaaggt tatcacaaca gcgaagcata cagacagtaa ggccttaagc cagggtgata
     1741 aatatattgt ggcttactct gtcataatga cagagcctct aacagacaag caaaaggagg
     1801 aattaagtaa aatatcgaac cagtctaatg aagattattt acgctattgg gtgctgattg
     1861 gtcaagcaag gatagatgat gccatggata ttgcgagcta tctagacgac ccgcagctct
     1921 tgatgtatgg cttgactaag aagattgatg atgttcagcg agatcctaat ctgacagcag
     1981 aggcgcgtac agagcagctt aacagctata agagcaaatt agacgagctc aaaaaggcct
     2041 acctgacgcc taaagaggaa aaagcagcag gctctagcag tgacaaggag tgacggagga
     2101 atttatgaca taccttattt atgacgacaa tgcctatcac ctttattcgg ataccgttta
     2161 tcagttgggg ccttcatcag ggtctgatat tttcctgccc ttgctggagg atattacctt
     2221 atcagtggag ggatcaggtg ttgtcctact ggaagagagc tacagcactg gtaagcattg
     2281 tgttgctctt tctgatgagg ttacagtgac cttacttatt cttgaagctg tcactaaata
     2341 cctgctgcca gactcctcgc tttacatttc aggagagact accgcagcac ttcaattgct
     2401 tgattaccct agtgagctgg tgctgaccct agactctgat tctgccagct gctatagccc
     2461 ggtgtcttat tatctaaatg gtaaatggac gaaaggcaag cagcctctta aagcatctga
     2521 tgaacttgtt ttttcagatg gcttagtgct tagttttcag gatcagctgc tatcgattca
     2581 gtccttgtat gctattcaga cagcattgct gcctcttaca gaggcagtag ctgaggatag
     2641 agccagtgaa tttcatcgtt ctcctaggat tatcctgcgt gagcctgagg gaaaggtgac
     2701 gattgcttct gtacccacag atgatgaagg gaaaagacag tctttattaa agctgatcat
     2761 aacgcccctt gcgatgattg tctttacagg gctctcttat gtctttttcc gaggtggggg
     2821 aatgctcatg atgatgatgg gaatgtctgt gattacgatt ggaagctcca ttcattctta
     2881 tttttcagat aaaaaatggc ataaagaagc ccagcagcaa aaaatcaagg attatctagc
     2941 ctacttggat accaagtatg tggagctagc aggctatcgt gaggagcaaa tcgaagcact
     3001 gctgtatcat taccctaata tgacgactat tcttgaaatg gcacaaaaaa cagatcgccg
     3061 tatttatgag aaggctccat atcattttga ctttttgacc taccgcttgg ggctaggtga
     3121 tactccagcc agctttcaca ttgattattc agattctgag ctgaccaagc atcatgaaaa
     3181 ggcaaagcaa agggttcaag agctgattgc ttattatcag gtgacagcac aggtgcctat
     3241 ccaaaatgcg attgccagtc caatcggtta tattggagca cgcaaggtcg tgattgagca
     3301 ggttcagcag ctgatgatgc agatcgctac cttccatagc tatcatgatg tacagtttat
     3361 tcctattttt cgagaagaag agctgccatt gtggaattgg agccggtggc tgcctcatac
     3421 taagctaaag gtgctaaata gtcgtggctt tgtttatagt cagcgaacac gtgaccaatt
     3481 gttgacctcg ctttatcagc tgatcaagga gcggcaatta gacagtgagc aggataaggg
     3541 gacagaaaag caatacactc cgcattatat agtgctgatt actgacatga gcctcatgct
     3601 tgaccacaat atcatggaat acatcaatga ggatttgtct catctaggca ttcattatat
     3661 ttttgttgaa gaggtcattg aaagtctccc tgagcatgtc aaaacagtta ttgattatcg
     3721 tggagataag catgctcagc tcattttgca ggaggggctc tacctcaata aggcctttac
     3781 cccacttcaa cccttatcta tgaaggataa ggaggtcttt gctagacata tggcagggat
     3841 taatcacgtt gagaccttac gcaatgcgat tccaaatagt gtgacctttc ttgaaatgta
     3901 tggcgttaac aaggtcgagg agcttaatct cttaaagcgc tggaaggaaa atgaggctta
     3961 tcagacaatg gctgttccgc ttggggtgcg tggtcgtgat gacatcttgt acctaaacct
     4021 tcatgaaaaa gcccatggac cgcatggctt aattgcagga acgactggat ctggtaaatc
     4081 agagctggtt cagtcttata ttttgtcgct ggcggtgaat tatcacccct atgaggttgc
     4141 ctttttgctg attgactaca agggtggtgg tatggccaat ctctttgctg atttaccaca
     4201 tgtcgttgga accattacca acctagatgg caatcaggcc aatagggctt tggtatcgat
     4261 taaggcagag ctgaaaaagc gtcagcggat tttccttgaa aatgatgtca atcatattga
     4321 tcaatacact aagctattca aggaaggacg agttaaggag cccctcccac acctgttaat
     4381 catcagcgat gaatttgcag aattaaaggc caatcagcca gaatttatgg acgagctggt
     4441 ctcaaccgcc cgtattggtc gttctcttgg tgttaagctc attttagcaa cgcaaaagcc
     4501 aagtggtgtc gttaatgacc agatttggtc gaatgcgaag tttaaaattg ccttgaaggt
     4561 tcaagatgtt gcagattctc gtgaggtgat taaaacccca gatgcagcag agattactca
     4621 ggttggtcgt gcttatctcc aggttggaaa caatgaaatt tacgagctgt tccaaagtgc
     4681 ctggtctgga gcagactaca atccaaaagg acgacatacc attcagcatg agacaacggt
     4741 ctatgaaatc acagctaatg gtcaatacca agcgattaac aaggacctta gtggacttga
     4801 caagaagaga gaagcaaaat ccatgccaac agagctagat gcggttgtag cagaggctca
     4861 gcagctcttt gaggacctgc atattccaaa ggtggccagt ccttggctgc cgcccctttc
     4921 agaaaaaatc tatgccagtg atttacagtc cacgcatttc aaggactatt ggggacagac
     4981 acaggacttg cagcctgttt tgattggcta tcaggacatt cctgaacgcc aagagcagtc
     5041 cccactctat tttcatatgg aaaaggctgg gcatatcctc ttagtgtcta gtcctggctt
     5101 tgggaagtcc accttccttc aaggctttgc tttagatgtg atgcgaaagc aaacaccagc
     5161 acaggctcat ttttacctct atgattttgg gacaagtggc ttgattgcgc tttctgattt
     5221 tccacatgtg gcagattact ttaccctaga tgagacagac aagatcatga aatcacttcg
     5281 ttatttaagt gaagaaatca agacccgtaa gcatgcccta tctaaggcta aggcaaccaa
     5341 cctcaatcag tacaatcaat tatccaagga taccttcccg gctctttttg tcatcattga
     5401 tggctttgat agtgtcatgg acgcaccatt tgtagatgct gtctacaatg tcttaaacgt
     5461 tattgcgcgt gatggggctt ccttgggaat gtaccttgtt gtgaccttat caagacttaa
     5521 taccatgagg ctacagctgc agtctaactt taagaccaag ctatccctct tcttgtttga
     5581 taatagtgat ttatcaagtg tggttggtcg ctcaaatatc ccactagatg atatcaaggg
     5641 acgagctatc atgaaacgtg acgacattat ccaatttcag attgccttgc catatagcag
     5701 tgagtactat acagattata tggcggaggt aaaaagagag gtcgaggcga tgagggctgt
     5761 ttatcaaggt gctttgccag cggctattcc aatgctgcca gaaaaggtta caccggatat
     5821 gatagcagcc atgtcagact ctgctcagga ttttgtgatt ggtttggagc gagaggacgt
     5881 tgttcctgct ggctttacct ttaaaaagtc aatactgatg gcctctgata gcccagcctt
     5941 tgtggctaac tattataagc tgcttgattt tcagttgcag cgtctggctg accagtatcg
     6001 tacggttatt ttagatccta gtcagcgtat tgcaaggcaa ttctttgagg atagtcaacg
     6061 ctttagcaca gccttagatg ttggagacac tctaagggct attgtagagg actttaaaaa
     6121 gcgtcttgca gcacctggtc aggattatca aaaatggtta gttgtgattc ctgatattgc
     6181 agctacagcg ctggcagcag ggattagcga ggaagacttt aaacagcttg tgaccgaggg
     6241 cagccagtat ggggtcacgc ttatctttgt cggagcttat caggatctgg tcaataatac
     6301 ctatgataat tttgtgaagc ttgcaaatca gctcattgag caggtctttt taggcatgcg
     6361 gatcagtgac caaagccata cacgatatgc ttatatcagc aatgagcctt cacttagacc
     6421 gacccagggc tatatcctat acccagaagg ctatgacttt attcaattat tagagattta
     6481 gaaaggaaca aagatgtcaa cagttacgat gcttccactt ggtagtattg tcattttaaa
     6541 gggcaatact aagaaaatga tgattattgc gcgtgtgatc gcagctccaa tcaaagggga
     6601 ggtttaccgc tttgactatg gtgcctgcct gtatccggag ggcatgatgg gggatagttt
     6661 gatttacttt aatcatgacg atatttttaa gattattcaa gaaggctatg ctgatgatga
     6721 caatgctctg atgttagaga cgatagcaca ggctttagca acaacggaca ttccaaaagg
     6781 agatgtttca gccttaaacg atagaaagac tgttgaggac tagcttatgg ggcaagttga
     6841 ctacaatcat atcaatcagc ttcaacgtca ggttgaccag cacagggcca gtctatcaac
     6901 ggctacagca gagatagcgt caatagacga aaagctagag cgcttgcgtt gtgccaaggc
     6961 ttctgttgga gcgattcaag gagatgttca tcagatcaag gtctctgtga tggctaagag
     7021 ggatcagcct gattggaagg gagaacgcaa ggaccgcttg atgtcgagct gggaggagtt
     7081 ctctcatgac tatcgccact ttcagctgga gctagatgct tattacgatg ccatttgtga
     7141 tacgataaca cgcttggaga atcaaaaata tgagcagcaa gggcttatcg gctggtgtca
     7201 gagcatgatt aatagcttgg gaaatgagat tgaaaagcta tttcatatta gggagggcta
     7261 gcatgtttgg tgttattcaa ttatctgagg ttgtgtttgg ggcgcatgtg ttaagcctga
     7321 ctgctgctaa ggctagcttg tctgatgtca aagctagctt tcccagccat cagtcatcaa
     7381 gtaaggtgct agatctgtat cagtcagagt ttgaagcact ctctcagctt gttgctgcct
     7441 atgctaggct tttggaaaag gatattgcct tgattgccga ggctggtcaa gaattagccc
     7501 taacagataa gcagttggga caagctatag gatttaggtt acaataggag gagggtatgg
     7561 gatataagat tcactttgaa gccatcagtg ccgcccaaca aagcactcaa accacgatca
     7621 gtgcttgggg agaaaggtcg tcttctcttt tatgatgttc aaagcaaggt aaatactttt
     7681 cttgaagttg tcaacgtttc tgaatccaaa agcattgcgc ttgatacctt tgataaattt
     7741 gttagttgct tcaagcttgg cgttagaata aggcagttca atggcattga tgatatagtc
     7801 gttatagcgt ataaaggtgt ttaaagtcgt tttgaaggtg tgattgagat gaggcaaagc
     7861 atcttgactt aacccaaaga agagctctgt cttcttttct tgcaagtgaa aaagaagtca
     7921 ttggtacaga tcataatagc cttttaactc agggattcgt ttgaaaatct tattgagaca
     7981 ttgtctagga gttaatgttt ctctaaaggt cctagagtag aaagtattaa gagatagttt
     8041 ccagttatcc tttagactaa gcttccaata gtatttaaga gcccgatatt caagagcttt
     8101 cttatcaaat ggcttcatga gttgaatgcg agtttgattg agcgctctac tcatgtgcta
     8161 cacaatgtgg aagcgatcga gaacaatttt agcttttggg agtgaactag tccagtggac
     8221 taattcagcc tgagcttaaa aatagaagag cgaagggttt aatgagagga atgtaacttc
     8281 ctgacatatc gacagtaaca actttgccct tatttctagc ttctttggag tacttaaaga
     8341 agtgatttcg aatggttgtt tgacatctgt tattgcgaat gataatgatt ttcttggtgt
     8401 tgaaatcctg agcgataaag gctagtttgc ccttttgata agagaattcg ttccaggaaa
     8461 gcacctcagg taaggtggtg taatcctctt taaagtgaca ttgcttgagc ttatgataga
     8521 cggtagaggt agagatagcg agtttagcag caatatgcgt aaaagcttct ttattgagca
     8581 atagctgaga gatcttctgt ctaactggtt cagagatttg gcaatttttc ttcacgagat
     8641 tggtttcaga gacagctacc ttccgacagg tttgacattg aaacctgctc tttttcaatc
     8701 gaataaggct agggaagcca ccgatttcga tgaaagggat tttagagggc ttctggaagt
     8761 catacttaat ctgagctctc ttacagtgct tacacttagg aggttgatag tccaatgtag
     8821 cgatgacttc gatatgtgta tcatgctgga tagccttatc gaaggtgata ttttgatctt
     8881 taattccgat gagtagtgtg gtatgatgaa tctgttccat aagacacttt ctaatgatgg
     8941 tctggtcgct tttcatgata agccttatgg gactttttgt gtactcaaaa gccctataat
     9001 ctccatagtg gacttaccca ctacagaaat tataaagccc taaaaaccaa tctgaggttg
     9061 ttgcaacagg attggttttt tcttgtgatt gcagatcaga cttttcaaaa gaacaagcac
     9121 attatctcag ctagactggt gcttgatagc tcctgagccc ttgtttgctg tagttgatag
     9181 gactttgctg atggcctagt caggcatatc gtatcaaatt caagtttttt catgtcactg
     9241 tctatagttt gtctgcccta ctttaggtag aatagaggta acttaagaga ggagtttatt
     9301 atggaattaa cgatgctttt gatggtttca gttttcattg cagggctgtt atcattcttt
     9361 tccccttgta tctttccagt tctgccggtg tatttaggca ttttgttaga ttctgatgat
     9421 tctaggtcta ttactatttt tggcaagaaa ctatattggt acggtattgt taagaccctt
     9481 gcttttattt caggtctatc taccattttt atcattttag gctatggggc tggtttactg
     9541 ggtaatattt tatatgctgc ttggtttcgc tacctacttg gtgcctttgt gattttgtta
     9601 ggtattcatc aaatggaaat cgtaaccatt aagaagctgc aatttcaaaa gagcgtagca
     9661 tttcaaaata agaaggaccg caatgctgtt ttaaatgcct ttttgctggg aattaccttt
     9721 agctttggtt ggacgccctg tgttggacca gttcttagct cggtgcttgc cttagcggct
     9781 tcaggtggca gtggggcttg gcagggtggc ttcttgatga ttatttatac cttgggctta
     9841 ggcctaccat ttttactact atcttttgct tctggtattg tgttgaagca ctttaataaa
     9901 ttaaaaccac acattcctct attgaagaag ttaggtggct tacttattgt tataatgggc
     9961 ttactgttga tgacaggaaa tctcaatagt ttatcaggtt tatttgaata aaggagaaga
    10021 aacaatgaaa aaaacaacat ttttaacaac aggcttagca tgtcttgctt tattaactgc
    10081 atgttcggcg aaggataaaa tggccatgaa tgatagtaaa aaagaccata tgaccaggac
    10141 cgatgacaaa tcaaagatga aaaaggatca aaaagacaag atgtcagaca agaaggatat
    10201 gatgtcagat gacaagcaca tgtcagatgc tgacaaggct agtaagaatg atgggcaaat
    10261 ggctccagat tttgaattaa agagcattga tggcaagact tatcgtttgt cagattttaa
    10321 aggtaagaag gtttacttga aattttgggc ctcatggtgt tctatctgct tatcaacctt
    10381 aggtgataca cagtcattag ctacgatgaa ggataaggat tttgaggtct taaccattgt
    10441 ttcacctggt catcagggtg aaaaatccga ggctgatttc aaaaaatggt ttgaaggaac
    10501 agactttaag gatttaccag tcttgctcga tccagatggc aagctgctag aggcttatgg
    10561 tgtgagatct tatccaactg aaatttttgt tggcagtgat ggtgttttag ctaagaagca
    10621 tattggttat gcaaagaaat cagagattga aaaaacctta aaggagatta aataagcaaa
    10681 ggaggctgtc tcatggaaca caaatggaag ttattgctac tcgtttttgg agccttagta
    10741 tttttaggag gtgttttgat ggtctttcaa agaggctacg ctactagcta ccataataat
    10801 caggtcaagc tgcctgccaa agggacgtct cagctcaaga agactgctaa tgccaagctg
    10861 cctgagaaga aaaaggagat ttaccttgca ggaggctgtt tctggggtgt ggaggagtat
    10921 ttttcaaatg ttgatggtgt tctagatgct gtttctggct atgctaatgg tagaggcgac
    10981 acaacctctt atcaattgct gcaccagaca ggacatgctg agacggttca ggttgtgtat
    11041 gatgctaatc ggattagctt aaaggagctt cttttacact actttagaat cattgaccca
    11101 acaagcctca ataagcaggg caatgatcgt ggcagtcagt accgtacagg catttattat
    11161 acggatccat ctgatttgac tactattgat atggtctttc aggaaaaagc ttcggattac
    11221 aaaaagaaaa ttgttgtgga aaaagctccc ctaaagagct ttaccaaggc tgaggaatat
    11281 catcaggatt acctcaagaa aaatcctaat ggctactgcc atattaatgt caacgaggct
    11341 tcatacccag tgattgataa gacaaaatac cctaagccaa gtaaggaaga gattaaaaag
    11401 aagctatcaa aggatgaata tcgtgtgacc caaaacaatg aaactgaaaa agccttttca
    11461 aacaggtact gggattcctt tgaagcaggg atctatgtag atgtggtcac tggtgagccg
    11521 ctgttttctt ccaaggataa atttgaatca ggctgtggct ggccaagctt tagcaggcct
    11581 attagcccag atgtgctacg ctataagaca gacaagagct tcaatatgaa ccgtacagag
    11641 gtgagaagcc gctcaggcaa ttcccattta ggtcatgtct ttaccgatgg tcctaaggat
    11701 cagggtggtc tgcgttattg tattaacagt ttatccattc gatttattcc aaaggctgaa
    11761 atggaagcta aaggctatgg ttacctttta acagcagttg attagaagat tatcctaaga
    11821 tttgttataa taagatgagg aagcacagat ggttgattat agttattaag acctgaagat
    11881 tacttcagtc gatattgcta aatgtgatca ggctcatgcc ctttagtctt gcttaagagg
    11941 tagtagcttt taaaagagtg attacgataa gaggcatttg ctcagagctt gtcctattta
    12001 gctcttgtcg agctatgtgc agagcttgta tgactatggt cactaagcat tagaaatagt
    12061 aggagaaatg gtgtgtactc attacttatt gttgaagacg aataccttgt gcgtcagggt
    12121 attcgttctt tggttgattt tgaccaattt gccatcgatc gtatagcaga ggctgagaat
    12181 ggtcaggtgg cttgggagtt gttccaagaa aatccttatg acattgtttt aacagatatt
    12241 aatatgccaa agcttaacgg cattcaactg gcagagctta taaaggcaag ggctccaaag
    12301 actcatcttg tttttttgac aggttatgat gatttcaatt atgccctatc tgccttaaag
    12361 ctaggggctg atgactacct gctaaagcca ttttccaaat cagatgttga agaaatgctc
    12421 aaaaagctaa agcagaaatt agaaaagctc aaaaaaacag aggcccttca aaaactagtt
    12481 gataagccgc agcaagaagg ctcagaaatt aagctagcta tccaagagcg tttagctgat
    12541 tcaagcctaa cgctaaagag cctatcaagc cagttaggct ttagccctaa ctatctaagt
    12601 gttttaatca aaaaggatct aggtttgcct tttcaggatt acttgattca ggagcgtctt
    12661 aaaaaggcta agctcttatt attaacaacg gatttgaagg tttatgagat agcagagcag
    12721 gttggctttg aggatattaa ttatttttcc cagcgcttta agcagttggt tggaatgaca
    12781 ccaaggcaat ataaaaaagg agaaggccaa tgaagcgcta ccctctttta gtacaattag
    12841 tgagttattt ttttctgatt gtgatttcac taatcactat tctgggagtg atttattatc
    12901 agaccagctc tcataatatc aggcagctca ttgaacgcga aaccagacag agcattcggc
    12961 agagctctca atttattgat gcctacatta agccattaaa ggagacaacc tcagccttag
    13021 ctagccatgc tgagattcag agctttgcta aggcagctaa cagtagtcat caagagcagg
    13081 tgttggcact gatgacaact gtgctgtcga ccaattcaga cctgcgctca gcggttctgg
    13141 tgacaaagga tggtcgtatg gtcacaacca acccaaagct aatcatgact acctcgcatg
    13201 atatgatggc agagccctgg tacaagtcag ctattgaccg caaggccatg ccggtgttga
    13261 cccctgcaag gcagctgtcc tcgcattcta aaaaggattg ggtggtttca gttactcagg
    13321 aggtagttga tgagacaggg aacaatttag gggtgctgcg attggatatt ggctacaata
    13381 ccatcaaatc ctccctagat caattgcagc ttgggcgtag gggctttgcc tttatcgtca
    13441 atgataagca tgaatttgtc tatcacccta aaaataccgt ctatagctca gagcgagaaa
    13501 tggccgcaat gaagccttac cttgctgttg ctgatggcta tacaaagcct aaggattatt
    13561 ttgtttacca aagggtgatt ccagacagtc aatggacctt gattggagtt gcctctttgg
    13621 atcagctgta tcatgtgcag cggcagattt tttggtcctt tttagggacg ggtctgcttg
    13681 caactgtcat ctgtggtctt gggacagtat ttgttctgag aagctggatt ggtcctatca
    13741 ggaggcttca ggctctcatt ttagctattc aaaagggtaa ccgtcagctg cgtgctgagg
    13801 aaattggctc gcctgagtta gctgatttgg cacgtcagtt taacgccatg ctggatcaaa
    13861 ttgatagttt gatgatttca gttgctgaca aggaaaaggc tattgggcag tatcgtctgc
    13921 aagccttagc cagtcaaatt aatcctcatt ttttgtacaa caccttagat actattattt
    13981 ggatggcaga gtttaatgac agccagcgtg tagttgatgt caccaagtct ctggctaagt
    14041 atttccgctt ggccttaaat cagggaaatg aattgattag ccttgctgat gaattggatc
    14101 acgctcgtca gtatttgttt atccaaaagc agcgctatgg tgacaagctg cactatgaga
    14161 tcaaaggtct tgagaaatac caggacttta tgattcctaa gctgattctt cagcccttgg
    14221 ttgaaaacgc tatttatcat ggtattaagg aggttgatag acctggaatg atcagagtaa
    14281 ctgtattaga agctgatcgt catgtgatat tatccgtttg ggataatgga aagggcataa
    14341 gcttagctga tgacagcagt caggccctgc ttgagtgtgg cggtgttggt ttaaaaaatg
    14401 ttgaccagcg cttgaaatta cagtatggtc atctctatag aatggcaatc actagcgagc
    14461 aggctgtttt tactgagatt aagctttatc ttcccaagcc gcttgatggc ctaaatgagc
    14521 tcccctaatc aatctgccct tagtagaaca aggaaaagag aggtttatgt ctttagaatc
    14581 cgattatttt aagcgaaaaa gtcctgtatt tgaggccctt atcccttatg gctttaccca
    14641 agagggtgac acttattgtt atcaggagtc atttatggag ggagatttca aggccttgat
    14701 tacgatcaag tcgtctggtc agctctcagc tagagtgatt gatactgacc ttggggagga
    14761 ctatctcccc ttgagaaatg atagacagca gggagtttat gttggtcagg ttcgtcaagc
    14821 ttatctagag cttcttggac gtttatcagc tgcctgcttt aggtctaccc cttttcagac
    14881 aaggcaggcc aaccaagtgg caacaagcat tagccagcag tggaatgatc cactagatta
    14941 cccctttgaa aaattcccta atattgccac ttatcgtgtt tctggcaagt ggtatgcgat
    15001 ggtattgccc ctgctagccg ataaattagg acaggtgcca aaggtcttac aggggcaaat
    15061 ggttgaggta ttgactgtta gaattgctcc taatcagcta acacacctct tgcagcaacg
    15121 tggtgtttac ccagcctatc atatgtctaa aaagacctgg attagcctat tactagatgg
    15181 tacactagca gatgatcagc tctgggagct agtcacgaaa agtcgtcaat tggctaatcc
    15241 taatggccta gctaacccag atggaccaga ttactgggtg attcctgcta atctcagcta
    15301 ttacgatatt gacgcggaat ttgcagctaa tcctgacatt ctctggacgc aaaaggcttc
    15361 cataaaagct ggagactatg tttttattta tatcactgca ccgaccagat caattcgcta
    15421 tgcctgtcag gtcttgagat cagacattcc taatcaaggc tatcggaaaa atgcgaagat
    15481 taagacctta atgtcgctac gcttgttgca ttgctacgaa gatggtttga tttcccttga
    15541 tttgatgaaa cagtatgggg ttaatgctgt tcgcggtcca agacggttaa gcccacaatt
    15601 agttgcattt ttgaaggaaa aagagtattt taaagatgtg aaacaaaaag aatgataagg
    15661 agagcgggta tgactcaatt tatagcagat cagagctttt gggaattatt tcctgatgct
    15721 aagctaggtg ttttgttgct caggaactat gacaatcagg aagactcccc acaagaggtc
    15781 aagcaattat tggcagacag ccatgacata gctaagcagt atttgactga agagtcgttt
    15841 agtgacaatg agatcattca ggtctatcgt caagcctatc agcgttttaa gacaaaaaag
    15901 ggagccagat ccagtattga ggccctccta aagagggtgg caaatggtca agtcctatcc
    15961 tccattaacc ctctggtgga tatttacaat acagccagtc taaggtttgg tctgccagtt
    16021 ggcgcagaag atagtgattg ctttgtaggt gacttacgcc tgacgttaac agagggaggc
    16081 gatgagtttt acctcattgg tgattctaaa aacagtccaa ctctgccaaa tgagctctgc
    16141 tacaaggacg atgctggtgc tgtttgccgc tgcctaaact ggcgcgatgg tgaaaggaca
    16201 atgattaccg atcgcactaa aaatgccttt ttagtcattg aagcattaga tagcaagacc
    16261 caagcaagac tacaggacgc ccttaagttt atcgaagaca aggctaagtg ctacctgaag
    16321 gcagaaacag cactatatac gctggatcaa gcctcaccaa gtatcacgtt ttaatcaaaa
    16381 aaagctagga agccagtatt cctagttttt tcagttgttc aggtgctttt atttggtgtt
    16441 gtcgagggag atttccttat agctgcaaga tatgacatga cagggaaaca gtttttgctt
    16501 gtttgatcta atcaagcgat taataaaagc ttttaagctg ttggttatgc taaagggctt
    16561 tcttaatcct atcagagaac tttaaaaaat agtataatgt agttaactta tgatgatagc
    16621 taaggaggtc agcatggagt tatttgacaa ggttgatgat acgttaaagg ctttagcgat
    16681 tgactaccag ctggttgagc atgagccagc tttaaccaca gagcaggcag accagttcat
    16741 agagggcatt gaaggggtta gaaccaagac aatgttttta acgaccagga aaaagaacca
    16801 tttttatctg atcattatgg atgatactaa gagactggat atgaatcgct tcaaggagct
    16861 tgttggagaa aagcagatta aaatggcatc agcagaatgc ttgcttgcca agatgcagct
    16921 gccaccagga gttgtttctc cttttggtct tttaaacaac gaggataagg atattcaggt
    16981 ttacgttgat aaagctattg ctcacgaagc tagaatgagc tttcacccaa ataccaatga
    17041 caaaaccatc tttattcaaa cagatgacct ctttaagttt ctagcggcta taggttacgc
    17101 ggtcaatatc gtggatctat agctaaattc aaggttcttc tagcggttct tgctcacatc
    17161 agttcacaaa gctggtggcc tagccaatcc agggcaaaca aaaagcacaa tagcctttct
    17221 tgactactga gaatagccag tagacccttg tgtcatatgc ttatctggta tttgagctta
    17281 aatctcaagg cttttaagta gaggatcaaa caaagaaaac gaccagcaga ccttgcgtga
    17341 tgactgatta tcaagtctgg taggagctaa aatcagtcat ggtcttgagg cctaaaacgt
    17401 cccatttgtc gctcctgttg ctagggcatt agttgacatg tatacccacg actaaccaag
    17461 ccgaggagag ctgtcgctcc cttctcagga gcgtggattg aaatgcaaaa gggatctgat
    17521 agacatttct gcttttaaag ctagtccatc aaaaaaacgc atgacaccac tgtagtggga
    17581 catcatgcgt ttttgctaag ctaaagtgat ttgacgcttc ctttgaaagg gttatttatt
    17641 gctgaagaaa aagggtggtg tgtaatggct caggatttca aagcaagctt tggcctgctc
    17701 attgtcctca cagataatca gacaggtatc atcaccacag atagtggcta cgatttctga
    17761 gatttgcata gcatcaagga tagagccaaa ggattgtgcc agccctggta aggtttttaa
    17821 aataatctga tgctgaacaa ccctgagcat gacaagggcg tcctccatat aaaagcgcaa
    17881 acgatgctcc caacgcgtct gagaaatggc cagcgcttca taatgcgtgt cattaccagt
    17941 tgtaaccttg acaaggttaa gctctttcat atcacgtgat aaggttgcct gtgtgatgct
    18001 tatcccattt tttcgtaagc gttcctgtaa ttcctgctgt gtgtgaatag ttgtttcaga
    18061 aattagagat cgaattaatt gatgacgtgt ttctttttta ttcatttctt ataatattcc
    18121 cctaatgatt agtaacattc agagtataac aaaaagatgg cagtgtgtaa agttttagat
    18181 gaaccgctta caaaaatagc ctttttatgt taaaataaaa cgggtgctta gaaaaggaga
    18241 tttgcgtgat tcgaagagaa gattatcaat accttagaaa acttgatgat ttctgtcatt
    18301 tttcaattga acaatttgac aagattgtcg gccaaatgga atttagacaa gctaaaaagg
    18361 atcatatgtt attttttgaa ggtgataaga gggacagact ctttttagtg acctcaggtt
    18421 attttaagat tgagcagtca gatcggacag gaacctttac ctatactgat ttcatacgac
    18481 atgggacaat ttttccctac ggggggctgt ttacagatga ctactatcat ttttcggtgg
    18541 ttgcgatgac agatgtcacc tacttttatt tcccgactga tttgtttgag gactattcct
    18601 tgcacaatca gcagcagatg aagcatctct acagtaaaat gtcgtccttg ctggagcttc
    18661 atgagctcaa ggtgcgcaat ctcatcacct ccagtgcaag ctcacgtgtg attcaatcct
    18721 tggctatttt actggttgaa atgggaaagg atagcgatac tctgcctttt cagctgacga
    18781 ctactgacat tgcacaaatg agtggaacaa ccagagaaac cgttagtcat gtctttagag
    18841 atttgaaaaa ggaaggcttg attgcagtca aggggaaata cctcacctac ctagataaaa
    18901 actattttct gcagtacaca acctaagatc aagtcaaaag gcttcgctta aaaagttttt
    18961 tgactttt
//
LOCUS       DARYXW010000036        18273 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.036, whole genome shotgun sequence.
ACCESSION   DARYXW010000036 DARYXW010000000
VERSION     DARYXW010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18273)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18273)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18273
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.036"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(85..1350)
                     /locus_tag="TV191_001026"
     CDS             complement(85..1350)
                     /locus_tag="TV191_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HEL1507551.1"
                     /translation="MAEFHFDIDQIANNAITKTDKTTDIITKLPTNTTGQISFYEKLS
                     PEQQQAITAKAPALVDTFMEDQNALLDFGQAAVEGVNATVNHILAEQKKLQIPQVDEL
                     LKNTNRELNGFIAKYKEATAAELEKKPTLLQKLFKQSKNTLQEFYFDSQTIEQKMDGM
                     AAAVVKQEDTLARNIVAAELLIEDNTKSIENLVGVIAFLEASQKETSSRALTLQQELA
                     VLDTTTPEYQVQSDLLARTTEVLNTLEQQHTEYLSRLYVAWATTPQMRNLVKVSSDMR
                     QKLGMLRRNTIPTMKLSIAQLGIMQQSVKSGMTADAIVNANNAALQMLAETSKEAIPN
                     LERTAQSPTISLTSVTALAESLVAQNNGIIAAIDQGRKERAQLEAAIIKSAETINDSV
                     KLRDQSIIQALLNEGKEKQETIEQTERQP"
     gene            complement(1364..2221)
                     /locus_tag="TV191_001027"
     CDS             complement(1364..2221)
                     /locus_tag="TV191_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507552.1"
                     /translation="MSRKYYQVSRRRKGFSWFGWLIGFAILVGVVENIDKAVLIFAAL
                     GVGYAAYRYSNRQARLKTATLEKRLEDLKATIQLADRKVKLLDHYLAKEDFTQYAILA
                     KQLLPQLSEIKKESGHLKEHMDISIYRRVTKKANDVESDVQLQLEKIQIAANLKAESL
                     KEQAADPIYKAPELRHYYDNIQADHHSILEKIKGADNHEELLALHEANMRRFQDILQG
                     YLKIKETPKNYYNADERLQQALEAIQQFDLDLDETLRKLNESELKDFDVSLRMMKGSA
                     QASEANTTN"
     gene            2564..3856
                     /locus_tag="TV191_001028"
     CDS             2564..3856
                     /locus_tag="TV191_001028"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEL1507553.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSSDAEVIARYQGGDNAGHTIV
                     IDNKKFKLHLIPSGIFFPEKISVIGNGVVVNPKSLVKELAYLHEEGVTTDNLRISDRA
                     HVILPYHIKLDQLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDRDIFAERL
                     KTNLAEKNRLFEKMYDSAPIAFDEIFEEYYAYGQEIKKYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREIGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLETVKICVAYDLDGKRIDHYPASLEQLKRCKPIYEELPGWSEDITGVRSLEDLPEN
                     ARNYVRRIGELVGVRISTFSVGPGREQTNILESVWATI"
     gene            complement(3971..4744)
                     /locus_tag="TV191_001029"
     CDS             complement(3971..4744)
                     /locus_tag="TV191_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEL1507554.1"
                     /translation="MTTKGIVFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCANPESQK
                     TLPEKMLSTDGLKTEIVGQEKTVEEIIAEVLKDLDFYEESGGGMTLSGGEIFAQFDFA
                     LALLKAAKAEGLHTAIETTAFAKHEQFAELINYVDFIYTDLKHYNRLKHTKVTGVRND
                     LIIKNIHYAFEMGKEVVLRIPVIPNFNDSLEDAKAFSELFNQLNINQVQLLPFHQFGE
                     NKYKLLGRSYDMADAVAYHPEDLVDYQQIFLNHHIHCYF"
     gene            4869..5615
                     /locus_tag="TV191_001030"
     CDS             4869..5615
                     /locus_tag="TV191_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEL1507555.1"
                     /translation="MNRLEKIIQLVFQKKKIDVNTLSEQLQVSKVTIRKDLDKLESKG
                     LLRRVHGYAVLNSGDDLNVRLSYNYNIKRRIAEKAAELVQDNDTIMIESGSTCALLAE
                     VLCQTKQNIKIITNSCFIASYIRQYSSCQLILLGGYYQPNSEVTVGPLLKEMISLFHV
                     DRVFVGTDGFDPAIGFMGKDMMRSEGVRYMAEASEELIILTDSSKLSKPSLVHQLSLE
                     AVDRMITDEQLEASTYKLLQEHGIAIDFIS"
     gene            5630..6610
                     /locus_tag="TV191_001031"
     CDS             5630..6610
                     /locus_tag="TV191_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEL1507556.1"
                     /translation="MKEGRKRLLAKVAYLHYVQGKSQTAISKQMNIYRTTVCRMLAKA
                     RAEGIVRIEIADYDANLFALEEYVRQKYGLEKLDIVSNQMEDSPSDTLVKVAKTAAEV
                     LRSTVKDGDKIGLSWGATLSSLIDELDPKVMKDIMVCPLAGGPSHINAKFHVNTLVYR
                     LARIFHGNSSFINAMVVQKDKQLTRGILQSKYFEETLTYWNHLDLALVGIGGEPNGHQ
                     TSQWRDLLTDKDYKQLADDKAVGEVCCRFFDQEGHSVHQELQDRTIGISLEQLARVPK
                     TIAVAVGQAKAKAILAALKAKFINYLITDKATIMAVLALDQDQTADTYLS"
     gene            6849..7169
                     /locus_tag="TV191_001032"
     CDS             6849..7169
                     /locus_tag="TV191_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEL1507557.1"
                     /translation="MELIVPDQIIMGLILNAGDAKQHIYQALKLAKAKDYEASDKELA
                     LADDALLEAHNLQTQFLAQEASGAKADITALFVHSQDHLMTTITEINFIKEIIELRKE
                     LAEN"
     gene            7194..7502
                     /locus_tag="TV191_001033"
     CDS             7194..7502
                     /locus_tag="TV191_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1507558.1"
                     /translation="MIKIGLFCAAGFSTGMLVNNMKVAAEKKGIACEIEAYSQGKLAD
                     YAPAIDVALLGPQVAYTLDKSEVICKENGIPIAVIPMADYGMLDGDKVLDLALSLIKE
                     "
     gene            7513..8817
                     /locus_tag="TV191_001034"
     CDS             7513..8817
                     /locus_tag="TV191_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL1507559.1"
                     /translation="MANMNAQKIIAPIMRFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     AGQIPFQGVNDAIASVLGADWTEPFMQVYQGTFAIMGLISCFSIGYSYAKNSGVEPLP
                     AGVLSLSAFFILLRSSYVPKKGEAIGDAISKAWFGGQGIIGAIIIGLVVGAIYTAFIR
                     RHIVIKMPEQVPWAIAKQFEAMIPAFAIFILSMLVYIIAKLVTGGGTFIEMIYAVIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGIVTALLLSNLDANKALLAAGDLS
                     LAKGAHIVTQQFLDSFLILSGSGITFGLVIAMIFAAKSKQYKALGKVAAFPALFNVNE
                     PVVFGFPIVMNPVMFLPFILVPVVAALIVYGSIAIGFMQPFAGVTLPWSTPAIISGFM
                     VGGWQGALVQALILVLSTVIYFPFFKVQDNIAYQNELAAEKA"
     gene            9098..11515
                     /locus_tag="TV191_001035"
     CDS             9098..11515
                     /locus_tag="TV191_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEL1507560.1"
                     /translation="MTEAKNPYFGTLTERMHRYREAVLDKKPYIDAERAILATEAYQK
                     HQNKPSNLKRAYMLQNILENMTIYIEDESLIAGNQASSNKDAPIFPEYTLEFVLNELD
                     LFEKRDGDVFYITEETKQQLRELAPFWENNNLRARCGVLLPKEVQVYMETGFFGMEGK
                     MNSGDAHLAVNYQKLLEVGLKGFEERTRAAKAALDLTIPESIDKYHFYDSVLIVIAAV
                     KAYAERYAKLARELAKTANPERQAELLEIARICDKVPYQPAETFAEAVQSVWFIQCIL
                     QIESNGHSLSYGRFDQYMYPYAKADLEAGRETEDSIVERLINLWIKTLTINKVRSQAH
                     TFSSAGSPLYQNVTIGGQTRDKQDAVNPLSYLVLRSVAQTKLPQPNLTVRYHKGLDNR
                     FMNECIEVMKLGFGMPAMNNDEIIIPSFIKKGVLEEDAYDYSAIGCVETAVPGKWGYR
                     CTGMSYINFPKILLITMNDGIDPASGKRFATGHGHFKDMTSYDELKAAWDATLREITR
                     MSVIVENAIDLGLEREVPDILCSALTDDCIGRGKTLKEGGAVYDYISGLQVGIANLSD
                     SLAALKKLVFEEGRLTTDELWHALETDFAGERGEEIRQMLINDAPKYGNDDDYADSLV
                     VEAYDTYIDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGKGTLATPDGRHAGTPL
                     AEGCSPEHSMDKKGPTSVLKSVAKLPTDEIVGGVLLNQKVNPQTLAKEEDKMKLMALL
                     RTFFNRLHGYHIQYNVVSRETLIDAQKNPEKHRDLIVRVAGYSAFFNVLSKATQDDII
                     ERTEHTL"
     gene            11530..12198
                     /locus_tag="TV191_001036"
     CDS             11530..12198
                     /locus_tag="TV191_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEL1507561.1"
                     /translation="MEYMLDTLNLEAIKKWNRILPLAGVTSNPSIAKKEGDIDFFERI
                     REVRAIIGDKASIHVQVVAQDYEGILKDAAAIRQQCGDSIYVKVPVTTEGLTAIKTLK
                     VEGYHITATAIYTTFQGLLAIEAGADYLAPYYNRMENLNIDPEAVIGQLAEAIDRECS
                     DSKILAASFKNVAQVNRAFALGAQAITAGPDVFEAGFAMPSIQKAVDDFGKDWQAIHH
                     RQTI"
     gene            12323..13414
                     /locus_tag="TV191_001037"
     CDS             12323..13414
                     /locus_tag="TV191_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEL1507562.1"
                     /translation="MKVFASPSRYIQGKNALFTNSDIIKKLGQKPVLLCDDIVYGIVG
                     ERFEGYLSEHGLPPVHVAFNGEASDNEINRVVAIARENDNDVIIGLGGGKTIDSAKAI
                     ADILEIPVIIAPTIASTDAPTSALSVIYTDEGAFEKYIFYAKNPELVLVDTQVICQAP
                     KRLLASGIADGLATWVEARAVMQKNGDTMAGGNQTLAGLAIAEACERTLFADGLKAMA
                     SCEKKVVTPALENVIEANTLLSGLGFESAGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLTQLFLENKSREEIDRYVDFYQAIGMPTTLKEMHLDTATEEDFLKIGRQATMAGE
                     TIHQMPFTITAEDVASALVAVDAYVCSRT"
     gene            13921..14973
                     /locus_tag="TV191_001038"
     CDS             13921..14973
                     /locus_tag="TV191_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEL1507563.1"
                     /translation="MIRKIGIVSLSSGMLGEANVKHELDLGLARLKQLGLEVTILPNA
                     LKGIDYFDQHPEARAADMIQAFADPSIDMILCAIGGVDTYRLLPYLFIEHQLQDVVNQ
                     KVFLGFSDTTINHLMLHKLGIKTFYGQSFLADICELADDMLPYSLAYFKELLETGTIA
                     EIRPSEKWYEERTDFSANSLGTQRIAHRNQGFELLKGPSLFKGEILGGCLESLYKLLD
                     SSKCSDSAKLCEQYQLFPDLSDWAGRLLLLETSEDKSDPAQYRRMLETLKATGIFSVI
                     SGLLVGKPIDNSYYDDYKQQLLAVVDNDIPILYNVNVGHATPRAIVPFGVMAVVDAKE
                     QVIRFVPDEHTDQNDV"
     gene            15002..15580
                     /locus_tag="TV191_001039"
     CDS             15002..15580
                     /locus_tag="TV191_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEL1507564.1"
                     /translation="MPKVDTITQVYFIRHAEPNYQNHNDVTRELSEHGVKASQDLVRQ
                     LAEVSIDAFYSSPYKRSIDTIAPLAASRAMEIKLIDDLRERKLADAWIEDFVDTAKKQ
                     WDDFTFKLPTGESLQEVQDRNIAALNRILKEAKGKTVVIGTHGTALSTLINYYQPDFG
                     FEDFDRYKHVFPWIVRASFDGDKLLGLNEFLV"
     gene            15779..16687
                     /locus_tag="TV191_001040"
     CDS             15779..16687
                     /locus_tag="TV191_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1507565.1"
                     /translation="MTNKTKRTGLVRKYGACSAAIALAALASLGAGKAVKADQPAALK
                     YPEPRDYFLHTREGDVIYDEDIKRYFEDLEAYLTARLGGIDKKVEEAAQKPGIPGPTG
                     PQGPKGDKGDPGAPGERGPAGPKGDTGEAGPRGEQGPAGQAGERGPKGDPGAPGPKGE
                     KGDTGAVGPKGEKGDTGATGPKGDKGERGEKGEQGQRGEKGEQGQRGEKGEQKPKGDQ
                     GKDTKPSAPKAPEKAPAPKAPKASEQSSNPKAPAPKSAPSKSAAPTGQKAALPATGEI
                     NHPFFTLAALSVIASVGVLTLKGKKD"
     gene            complement(16923..18269)
                     /locus_tag="TV191_001041"
     CDS             complement(16923..18269)
                     /locus_tag="TV191_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1507566.1"
                     /translation="MKKNQVTRYSLLIPAALMAAGLAMSTNSSVAFADESPAVDNHTV
                     VQPRLGEDKDTADTANQQLSDSTEVMADKPITKASETANPVAAADKLPLDTNQSAEDI
                     IAVKKAYIAKNTGLPLDKIQLLDTSEGKALMYPHDDHHHVILLDKIDVSKPFDDGQSS
                     HHSDHAHHHHDDVIEGSFAFTATVIDPEGKVLSGKDVQVVDITSGRKTLATVTTDEKG
                     QAVFDKLPLGRSLSIFVNGVPQGYTVRTGVDGDKHSASFTVDGKGTVEPEYSKTPLVV
                     IVRNEDAEPLSGQEVTLKHRVGRVIEKVTTGADGKAVFSKGLLDGTFYEIFVNGKKLS
                     QATTGEERSVALDAKDIKKSSPHSKPQEDAPKVPETKPETKPEAKPLSPEKADQAGKV
                     AAPAHTASKAAAAKAEMKKTTNQLPATGEAVNPFFTAAALAVMATAGVAAIKRKEN"
BASE COUNT         5059 a         3751 c         4203 g         5260 t
ORIGIN      
        1 tgacagaagg gtatttttga ttgttaccaa tcaaaaagcc acaggctggg tagctgtggc
       61 aggtctgtta tatcaggagc tgctttaagg ctggcgttct gtctgctcga ttgtctcctg
      121 cttttctttg ccctcattga ggagagcttg aatgatgctt tggtcgcgca gcttgacaga
      181 atcattaatg gtttctgctg atttgataat ggctgcttcc agctgagctc gctccttgcg
      241 tccttgatca atggcagcaa tgatgccgtt gttctgggca actagacttt ctgctagtgc
      301 tgtcactgag gtcaacgaaa tcgttgggct ttgagctgtc cgctcaaggt ttggaatcgc
      361 ttccttgctt gtctcagcta gcatttgtag ggcagcgttg ttggcattga caatggcgtc
      421 tgcggtcatt ccagacttga cagactgctg catgatacct agctgagcaa tagataattt
      481 catggttgga atggtattgc gtcgcagcat gcctagcttt tgtcgcatgt cagaggacac
      541 cttgacgagg ttacgcattt gcggtgttgt tgcccaagcc acatagagtc gactaaggta
      601 ttcggtgtgc tgctgctcaa gggtattgag cacctctgtt gtcctagcca ataggtcaga
      661 ttgcacctga tactctggtg ttgtcgtgtc aagtactgca agctcctgct gcaaggtaag
      721 ggcgcggcta gaggtttcct tttgactagc ttcaagaaag gcaatcacac caaccagatt
      781 ttcaatcgac ttggtattgt cctcaatcaa gagctctgcg gctacaatat tacgagcaag
      841 cgtgtcttct tgcttgacaa cagctgcagc cataccgtcc attttttgct caatggtctg
      901 agaatcaaag taaaattcct gaagcgtgtt cttgctttgt ttgaatagct tttgcaaaag
      961 cgttggcttt ttttcaagct cagcagcggt cgcttcctta tatttggcaa taaaaccatt
     1021 aagctcacga ttggtgtttt tgaggagctc gtcaacctgt ggaatttgta atttcttttg
     1081 ctcagctaga atatgattaa cagtagcatt aactccttca acggctgctt gaccaaaatc
     1141 aagtaaggca ttttggtcct ccataaaggt atcaacaagt gctggtgcct ttgcagtgat
     1201 agcctgctgc tgctcaggac tcagcttttc gtagaaagaa atttgtccag tagtattggt
     1261 tggtagctta gtgataatat cggtggtttt atctgtttta gtgatagcat tattagcgat
     1321 ctggtcaata tcaaagtgaa attctgccat aatagctcct ttatcagttg gtagtgttag
     1381 cctcgctagc ttgagcagag cccttcatca tgcgcagact aacatcaaaa tcctttagct
     1441 cactttcgtt aagcttcctt agggtctcat caaggtccag gtcaaattgt tggatagcct
     1501 caagagcctg ctgcaagcgc tcatcagcat tgtaataatt tttaggtgtt tctttgattt
     1561 ttaggtagcc ctgcaaaatg tcttgaaacc tgcgcatatt agcctcatgg agtgctaaga
     1621 gttcctcgtg attatcagct cccttgattt tttctaaaat cgagtggtgg tcagcctgga
     1681 tattgtcata atagtgacgt agctcgggcg ccttataaat ggggtcagct gcctgctcct
     1741 ttaggctttc agccttcaga tttgctgcga tttgaatctt ttcgagctgt agctgcacat
     1801 cgctttccac gtcattagcc tttttggtca cacgacggta aatgctaata tccatgtgtt
     1861 ccttgaggtg accgctttct tttttgattt cactcaattg cggcagtagc tgcttggcta
     1921 aaatggcata ctgtgtaaaa tcttccttag ccagataatg atcaaggagc ttaacctttc
     1981 ggtcggcaag ctgaatagtt gcctttaaat cctccaagcg tttctcaagt gttgccgttt
     2041 ttaagcgagc ctgacggttc gaatagcgat aagcagcata accaacaccc agcgctgcaa
     2101 aaatcagaac agctttgtca atattttcta caactcctac taaaatcgcg aagcctatca
     2161 gccagccaaa ccagctaaag ccctttcttc gtcgagatac ttggtaatat tttcgtgaca
     2221 tgtaaaactt cctttgtact ttttatcaca gtaaacaatc aattagttct attttacctt
     2281 aaaaatgtga tttcttaaag gaaagattag cagatttagc attattttcc ttcaaagact
     2341 ggtcttgctt gctttttagt gaaatgtttg ctttctgcct gttttcagaa aaaagcattt
     2401 gccatttgat attttttctt aataatacca aggaaagata gcagaaaacc acattttttg
     2461 ctataatgag gtgtaacaga cacttgcagg tgagagtcct gccacattta tcaagaaagg
     2521 tgggggctct ctttctttgt tgagatgagc ctatatcgaa gatatgacat cagtagtagt
     2581 agttggtacc cagtggggtg acgaaggtaa gggtaagatc actgactttt tatcctcaga
     2641 tgcagaagtg attgcacgtt accaaggtgg tgacaatgca ggacatacca ttgttattga
     2701 taacaagaaa ttcaagctgc acctgattcc atcaggtatt ttcttcccag aaaagatttc
     2761 tgtgattgga aatggtgtgg ttgtcaatcc aaaatccttg gttaaggagc ttgcttacct
     2821 gcatgaggag ggcgtgacca cagacaattt gcgcatttct gatcgtgctc atgtcatttt
     2881 gccataccat atcaagcttg accagcttca agaggaagca aagggtgaca ataaaatcgg
     2941 taccaccatc aagggcatcg gtccagccta tatggataag gcagcacgtg ttggtatccg
     3001 tattgcagac ctgttagaca gggatatttt tgctgagcgc ttaaagacga atctggctga
     3061 gaaaaatcgt ctttttgaga aaatgtatga cagcgcaccg attgcatttg acgagatttt
     3121 tgaagaatac tatgcttatg gtcaagagat caaaaaatat gtgacagaca catctgttat
     3181 tttgaacgac gctcttgatg cgggcaagcg tgtccttttt gagggagctc aaggggttat
     3241 gcttgatatt gatcagggaa cctatccatt tgtcacctca tctaatccag ttgcaggcgg
     3301 tgtgaccatt ggttcaggag tcggaccaag caaaatcaac aaggttgttg gagtatgtaa
     3361 ggcctatact agtcgcgttg gtgatggacc attccctacc gagttatttg acgaggttgg
     3421 tgagcgcatt cgtgagattg gtcatgagta tggaacaacc actggtcgtc cacgtcgcgt
     3481 tggctggttt gattctgttg tgatgcgtca tagccgtcgt gtgtcaggca ttaccaatct
     3541 atcacttaac tctattgatg tgctatcagg ccttgagact gtaaaaatct gtgtcgctta
     3601 tgaccttgat ggtaagcgca ttgatcatta cccagcaagc cttgagcagc taaaacgctg
     3661 caaaccgatt tatgaagagc ttccaggctg gtcagaggat attaccggtg ttcgcagcct
     3721 tgaggatctc ccagaaaatg ctcgcaacta tgttcgtcgt attggcgaac tggttggtgt
     3781 tcgtatctca accttctcag taggtccagg acgtgagcaa accaatatcc ttgaatctgt
     3841 ttgggcaact atctaagctg tctattgtga tagcaccagc cttagctgaa tattaacgaa
     3901 aacacgagca atcctaagga aggttatccg gaggagctgc tcatgttttt taggtatagg
     3961 gcttttaaga ttaaaaatag caatggatat gatgattgag aaagatttgc tgataatcca
     4021 ccagatcctc tgggtgataa gcgacagcat cagccatgtc atagcttctg cctagcaatt
     4081 tgtatttgtt ttcaccaaac tggtgaaagg gaagtagctg cacctgatta atgtttagct
     4141 gattgaaaag ctcagaaaat gccttggcgt cctccaaaga atcgttgaaa ttcggaatga
     4201 cagggatacg caagacgact tccttgccca tctcaaaggc gtagtggata tttttaatga
     4261 tcaggtcatt tcgcaccccg gtgaccttgg tgtgctttag gcgattatag tgcttcaaat
     4321 cggtataaat aaagtctaca tagttgatca gctcagcaaa ttgctcgtgc ttagcaaagg
     4381 ctgtcgtttc gatagctgtg tgtagccctt ctgccttagc agcctttaga agcgctaagg
     4441 caaagtcaaa ttgagcaaag atttcaccgc cagacaaggt cataccaccg ccagattcct
     4501 cgtaaaaatc aagatccttt aaaacctcag caataatctc ttcaaccgtc ttttcctgac
     4561 caacgatttc tgtctttagt ccatctgtgc ttagcatttt ttcgggtaac gttttttgtg
     4621 attcgggatt ggcacaccag ggacagcgta agggacaccc cttgagaaat acagttgtgc
     4681 gaatgcctgg tccatcgtgt atgctaaaat gctggatatt aaatacaatg ccttttgtcg
     4741 tcatagcgag acttcctttc gttctaggac tatcataaca gataaacgta aataaatcaa
     4801 ttacgaacga aagttatttt tgcttttcat ttaccgccat aattgttaca atggaaagga
     4861 ggtaaattat gaatcgttta gaaaaaatta tccaattagt atttcaaaag aaaaaaatag
     4921 atgttaatac tttatctgag cagctacagg tctccaaggt aaccattcgt aaggatttag
     4981 acaagcttga aagtaagggg ctgctgcgtc gtgtgcatgg ctatgcggtg ctcaatagtg
     5041 gtgatgattt gaatgtgcgc ctgtcctata attataacat caaaaggcgg attgctgaaa
     5101 aggctgccga gctggtgcag gacaacgata ctatcatgat tgagtcagga tcgacctgtg
     5161 ccctgttggc agaggtgctc tgtcaaacca aacaaaacat caaaatcatc accaactcct
     5221 gctttattgc aagctacatt cgtcagtata gtagctgtca gcttatcctg ctggggggct
     5281 actatcagcc taattctgag gtgaccgtag gcccactttt aaaggaaatg atttcgcttt
     5341 ttcatgtgga tcgtgttttt gttgggacag atggctttga tccggcaatt ggctttatgg
     5401 ggaaggatat gatgcgctca gagggcgtcc gttacatggc agaggcttct gaggagctta
     5461 ttatcctgac agattctagc aagcttagca aacccagtct ggttcatcag ctatcgcttg
     5521 aggctgttga ccgtatgatc acagatgagc aattggaggc aagcacctat aagctcctgc
     5581 aagagcatgg tattgccatt gactttatat cgtagcgtag ggaactcaaa tgaaagaagg
     5641 acgtaaacgc ctgcttgcca aggttgccta cctgcattat gtgcagggca aaagccaaac
     5701 cgctatttca aagcaaatga atatttaccg aacaacggtc tgtcgcatgc ttgccaaggc
     5761 tagggctgaa ggcattgtgc gtatcgagat agctgattat gatgctaatt tgtttgcctt
     5821 ggaggagtat gttcgtcaaa aatatggctt agaaaagctt gatattgtat ccaatcaaat
     5881 ggaagatagc cctagtgata ccttggtaaa ggtggccaaa acagcagccg aggttttgcg
     5941 cagtacggtc aaggatggtg ataagattgg cttatcgtgg ggggcaacgc tgtcaagtct
     6001 gattgacgag ctggatccta aagtaatgaa ggatattatg gtgtgtccct tggctggtgg
     6061 tcctagtcat atcaatgcca agtttcatgt gaatactctg gtttatcgct tagcaaggat
     6121 ctttcatggc aatagctcct ttatcaatgc tatggtggtt cagaaggaca agcagctaac
     6181 cagagggatt ttgcagtcca agtattttga agaaaccctg acctattgga accatcttga
     6241 ccttgctctg gtcggtattg gaggagagcc aaatggtcat cagaccagtc agtggcgtga
     6301 tttgttgact gataaggact ataagcagct ggcagatgac aaagctgttg gtgaggtctg
     6361 ctgtcgcttt tttgatcagg aggggcatag tgttcatcag gaattgcaag acagaacgat
     6421 aggcatttca ctggaacagc tcgcgcgtgt gcctaagaca atagctgttg ctgttggtca
     6481 agctaaggcc aaggctattt tagcggcttt aaaggctaaa tttatcaatt acctcatcac
     6541 cgataaggct actatcatgg ctgtcttggc tttggatcag gatcagacag ctgacaccta
     6601 tctctcatag caatagctta atcagaagac gattgttttc tgattttttt gtgaccaaaa
     6661 atcttgcaaa gcatcacttt tgcacaatag tgctaaaaaa taaatacagc acacaatata
     6721 ttgacgaagg aagtaaaaat gataaaatga acttatcaaa gaaatgtaaa cgattacaaa
     6781 cgcaagctgt ttttttacga aaaaagcaag ggtaatcctt acatgagcac gtcacaaagg
     6841 agaaacaaat ggaattaatt gtaccagacc aaatcatcat ggggttaatc ctaaatgcag
     6901 gagatgcaaa gcagcatatc tatcaagccc taaagctggc taaggctaaa gactatgagg
     6961 ctagtgacaa ggagttagcc ttagctgatg atgctttatt agaggcgcat aatttgcaga
     7021 cacaattttt agctcaggag gctagcgggg caaaggcaga cattacagcc ttgtttgtcc
     7081 attctcagga tcacttgatg acaactatta cagaaatcaa ttttatcaaa gaaatcattg
     7141 agcttcgtaa ggaattagca gaaaactaaa gatcatatca aaaggaggac gttatgatta
     7201 aaattggctt attttgtgca gcaggctttt caacaggcat gcttgtgaac aacatgaagg
     7261 tggctgctga gaaaaagggc attgcttgtg agattgaagc ctactcacaa ggaaagctgg
     7321 cagactatgc accagctatt gatgttgccc tcttaggtcc acaggtggct tataccttgg
     7381 ataagtcaga ggttatctgt aaggaaaacg gcattccaat agctgttatc ccaatggctg
     7441 attatggtat gctagatggt gataaggtgc ttgacttagc gctcagcttg ataaaggaat
     7501 aggagcttgg tcatggctaa tatgaatgct caaaaaatca ttgcaccgat tatgcggttt
     7561 gttaatatgc gtggcattat cgctctaaag gacggtatgc tggcgatttt acccttgacg
     7621 gttgtcggaa gtctttttct tattgcaggt cagattccct ttcagggggt caatgacgct
     7681 atagcgagtg tccttggggc agactggaca gagccattta tgcaggttta tcagggtacc
     7741 tttgctatta tgggcttgat ttcctgcttt tcgattggct attcctacgc taaaaattcg
     7801 ggtgtggagc cactgccagc aggtgtgcta tcattgtcag ccttctttat cctgctaagg
     7861 tcctcttatg tgccaaaaaa gggtgaggct attggtgatg ccattagtaa ggcttggttt
     7921 ggtggtcaag ggattattgg tgccatcatt attggcttgg tggttggtgc gatttataca
     7981 gcctttattc gtcgtcatat cgtcatcaaa atgccagagc aggtgccgtg ggccattgcc
     8041 aagcaatttg aagcgatgat tccagccttt gcaatcttta tcctgtcaat gcttgtttat
     8101 atcattgcaa agctagtgac aggtggcggc acctttattg aaatgattta cgctgtgatt
     8161 caggtgcctc tacagggctt gactggctct ctttacggtg cgattggtat tgcctttttc
     8221 atctccttcc tatggtggtt tggtgtgcat gggcaatcag tggtcaatgg tatcgtgaca
     8281 gcgctgctct tgtcaaatct agatgctaac aaggccttgt tagcagcagg tgatttgtct
     8341 ttggctaagg gtgctcatat tgtgacgcag caatttttag attctttctt aattttatca
     8401 ggctcaggta ttacctttgg cttagtgatt gccatgattt ttgcagccaa atcaaagcag
     8461 tacaaggctc taggcaaggt agcagccttt ccggctctct ttaatgttaa tgaaccggta
     8521 gtctttggct ttccaattgt gatgaaccca gtgatgtttc tgccatttat tttggtgcca
     8581 gttgttgcgg ctctgattgt ttatggctct attgcgattg ggtttatgca gccatttgca
     8641 ggtgtaacac ttccttggtc tacaccggct attatctcag gctttatggt tggtggctgg
     8701 cagggggctc ttgttcaggc tttgattctt gtcttgtcaa ccgttattta cttcccattc
     8761 tttaaggttc aggataatat tgcttatcaa aatgaattgg cagctgaaaa agcttaacag
     8821 tatgctgata tcaatcacca tgacttaaaa acagtcttta gtcactagct atagcattcc
     8881 tagagaaggg cttagagaag gaggatttct tcacgtaacc atctcaatga ggtggttttt
     8941 ttgaaagaga ctcttagaca agtctatttt tgcacgatag tgcaacttta aatgaatagc
     9001 tgaatgctat ggatatgata ggcaaaatgt tttaaatatg gtaaaataat tacgaaagaa
     9061 agtaatttaa tttcgtaaga aacaaaggag gcctaatatg actgaagcaa agaatcccta
     9121 ttttggtaca ttaacagaaa gaatgcaccg ctatcgtgag gcagttctag ataaaaagcc
     9181 ttatattgat gctgagcgtg ctattttagc aacagaggct taccaaaaac accaaaacaa
     9241 gccatctaat ctaaaacgcg cttacatgct gcaaaatatt ttggaaaaca tgaccatcta
     9301 cattgaggac gaaagcttga ttgctggtaa tcaggcgtct tctaacaagg atgcacctat
     9361 ctttccagag tacactcttg aatttgtcct aaatgagctt gacctttttg aaaagcgtga
     9421 tggcgatgtg ttttacatca ctgaagaaac caagcagcag cttcgcgagc ttgcaccctt
     9481 ctgggaaaat aacaatttgc gggcccgctg tggtgtcttg ctgccgaaag aggttcaggt
     9541 ttatatggaa actggcttct ttggcatgga aggcaagatg aattcaggag atgcccattt
     9601 agctgtcaat taccaaaagc tattagaggt tggcttgaag ggctttgagg aacggactcg
     9661 tgctgccaag gctgcgcttg atttgactat tcctgaaagc attgataagt accattttta
     9721 tgattctgtt ctgattgtga ttgctgcggt taaggcttat gcagagcgct atgccaaatt
     9781 ggcgcgtgag ctggccaaaa cagctaatcc agagcgtcag gcagaattgc ttgaaatcgc
     9841 gcgtatctgt gacaaggtgc cttaccagcc ggcggaaacc tttgctgaag cggtccaatc
     9901 agtttggttt atccagtgta ttcttcagat tgagtcaaat gggcattctc tttcttatgg
     9961 ccgatttgat caatacatgt atccatatgc caaggctgat ttggaggctg gtcgtgaaac
    10021 agaggattct atcgttgagc gcttgattaa cctttggata aagactctga ccatcaataa
    10081 ggtacgcagt caggctcata ccttctcatc agcaggtagt ccgctgtatc aaaatgtcac
    10141 cattggtggg caaaccagag ataagcagga cgctgtaaat cctctatcct acctagtgct
    10201 tcgcagtgtg gctcaaacca aattaccaca accaaaccta accgttcgat atcacaaggg
    10261 cttggataat cgttttatga atgaatgcat tgaggttatg aagcttggct ttggtatgcc
    10321 agctatgaac aacgatgaaa tcatcattcc gtcctttatc aaaaagggtg tccttgaaga
    10381 agacgcctat gattattcag caattggctg cgttgagaca gccgttccag gtaaatgggg
    10441 ctatcgctgt actggtatga gctacattaa ctttccgaag attttgctta tcaccatgaa
    10501 tgatggtatt gacccagctt cgggtaagcg ctttgcaaca ggacatggtc acttcaagga
    10561 tatgacctct tatgacgagc taaaggcagc ttgggacgcg actctgcgtg aaatcactcg
    10621 catgagtgtc atcgtagaaa atgccattga ccttgggctt gaacgagagg tgccagacat
    10681 tctttgctct gcattgaccg atgattgtat cggccgaggc aagacgctca aagaaggtgg
    10741 agcagtctat gactacatct caggcttgca ggtggggatt gctaacctgt ctgattccct
    10801 agctgcactg aaaaaattgg tgtttgagga gggtcgccta accactgatg agctctggca
    10861 tgctctagaa acagactttg caggtgagcg tggtgaagag atccgtcaaa tgctgattaa
    10921 cgatgcacca aaatatggta atgatgatga ctatgctgat agcttagtgg ttgaagccta
    10981 tgatacctac attgatgaaa ttgctaaata ccctaatacg cgctacggac gtggtccgat
    11041 tggtggtatt cgctactcag gcacctcatc tatttcagct aatgtcggcc aaggtaaggg
    11101 aaccttagct accccagatg ggcgtcatgc aggaacaccg cttgctgagg gctgctcacc
    11161 agagcacagt atggataaaa aaggaccaac ttctgttttg aaatccgttg ccaaattgcc
    11221 aacagatgaa attgtaggtg gggtcttact caaccaaaag gttaatcctc agacactagc
    11281 aaaagaagaa gacaagatga agctgatggc tctgcttcgg accttcttta acaggctaca
    11341 tggctatcat attcaataca acgtcgtctc acgtgaaacg cttattgatg ctcaaaagaa
    11401 tcctgaaaag caccgcgact tgattgtgcg tgtggcaggc tattcagcct tctttaatgt
    11461 tttatcaaaa gccactcagg acgatatcat cgaacgtacc gaacacacac tataggagaa
    11521 caattactta tggaatacat gctagatact ctaaatctag aggctattaa aaagtggaat
    11581 cgcattttac cccttgcagg ggtaacctca aatccttcaa ttgctaaaaa agagggagat
    11641 attgattttt ttgaacgcat tagagaggtt cgtgcgatca ttggagataa ggcctctatt
    11701 catgtgcaag tcgtggcaca ggattatgaa ggtattttaa aggacgctgc ggctattcgt
    11761 cagcaatgtg gtgatagtat ttatgtaaag gttcctgtga caacagaggg actcacagcg
    11821 atcaaaaccc taaaggtaga gggctaccat atcacagcta cagccatcta tactaccttc
    11881 caaggcttac tggccatcga agcaggagca gattatctgg caccttacta caatcgcatg
    11941 gaaaacctca atattgatcc ggaggctgtg attggccagc tggcagaggc cattgatcgt
    12001 gaatgctctg atagtaaaat cttggcagcg agcttcaaaa atgtagctca ggtcaaccga
    12061 gcctttgctt tgggtgctca ggccatcact gctggtccag atgtctttga ggcaggcttt
    12121 gcgatgccat ctatccaaaa ggctgtagat gattttggca aggattggca agccattcat
    12181 catcgtcaaa ctatttaaaa gccatctaac ccatcgttat atgagcaaga gcagggacgc
    12241 ttctatcagc atagctagac tagtcttgct cactcttaga tggtgagaag cgtcaaaaat
    12301 ctgatttaga aagaggaaca tcatgaaagt atttgcaagt ccatcacgct atattcaagg
    12361 gaaaaatgcc ttatttacca atagtgacat catcaaaaag ctagggcaaa agccggtatt
    12421 gctctgtgat gatattgttt acggcattgt cggagaacgt tttgagggct atttaagtga
    12481 gcatggtcta ccacctgttc acgtagcctt taatggcgaa gcgtctgata atgagattaa
    12541 tcgtgtcgtt gccattgcta gagaaaatga taatgatgtc attatcggac ttggcggagg
    12601 caagaccatt gacagtgcca aggcaatcgc tgacatcttg gagataccag tgattatcgc
    12661 tccaaccatt gcctccactg atgctccaac atcagcccta tcagtgattt acacagatga
    12721 gggcgccttt gaaaaataca ttttctatgc taaaaatcct gagcttgtct tggttgatac
    12781 tcaggttatc tgtcaagcac caaagcgctt gctggcttca ggtattgctg atggtctagc
    12841 cacttgggta gaagcgcgtg cggttatgca aaaaaatggt gacacgatgg caggcggcaa
    12901 ccaaaccttg gcaggacttg ctattgctga ggcctgcgag cgtaccctgt ttgctgacgg
    12961 tctcaaggca atggctagct gtgagaaaaa ggtcgttact ccagctttag aaaatgtgat
    13021 tgaggctaat accttattaa gtggtcttgg ctttgaaagt gcaggacttg ctgctgctca
    13081 tgctattcac aatggcttta cagctttgac aggtgacatt catcacctca ctcatggtga
    13141 aaaggtggcc tatggcaccc taacacagct tttcctcgaa aataaatcaa gagaagaaat
    13201 tgaccgctac gttgactttt atcaggctat cggaatgccg acaaccctaa aagaaatgca
    13261 tttagacacc gccaccgaag aggatttctt aaaaataggg cgtcaagcaa ccatggcagg
    13321 agaaaccatt caccaaatgc catttaccat cacagcagag gacgttgcct cagcgcttgt
    13381 tgctgtagat gcttacgttt gcagcagaac ttaatgcaga actgctaaag ttctcttagc
    13441 cttatcagga gcctattgct ggtagctctt gaccaaagga ttgtacctac cttagcctta
    13501 attcaactgt tagaggtgtt cctcttgctg tggtaagaga ggttctttac tgctaaaggc
    13561 tcattctcag ggcaagctgg cccctccaaa tcatttaaaa agtcgtaaat ctaatcaata
    13621 atggctatca gtataggcta ctggtagtca ttattctata tctgatttat gagaacatac
    13681 cagtcagcag ctttgctgtg ccacctattt cttgtcatta cagtagctta gctttatagc
    13741 tgacagagca aatgcttcct catctattag ctcttaattc aaccgctaca gtaatagaaa
    13801 aagctaatca aagtaagggc tagttttttt tggtatcgct attaacagta tgtattagag
    13861 gctatcagcc tagccattat tgtggtataa tgacacaaca actttttaag gaggttagct
    13921 atgattcgga agattggtat tgtcagcttg tctagtggta tgcttggcga ggctaatgtc
    13981 aagcacgaat tggatttagg cttagcccgt ttaaaacagc taggcttaga ggtaacgata
    14041 ctcccaaatg ctttaaaggg catagactat tttgatcagc accctgaagc aagggcagca
    14101 gatatgattc aggcctttgc agatccgtct attgacatga ttttgtgtgc cattggtggg
    14161 gtggatacct atcgcctctt gccctatctg tttatcgaac atcagctaca agatgttgtc
    14221 aatcaaaagg tctttcttgg attttctgac accacgatca accacttgat gcttcataag
    14281 cttggtatta aaacctttta tggtcagtcc tttcttgccg atatttgtga gctggctgat
    14341 gacatgctgc cttactcgct ggcttatttt aaagagcttc ttgagacagg aactatcgct
    14401 gagatcagac ctagtgagaa gtggtatgag gagcggactg actttagtgc aaacagcctt
    14461 gggacacaga gaatagctca tcgcaatcaa ggctttgaac tattaaaagg tccgtcctta
    14521 ttcaagggag agatactagg tgggtgttta gagtcacttt ataaactatt ggattcgtca
    14581 aagtgttcag atagcgctaa gctctgtgag caataccagc tctttccaga tctgtctgac
    14641 tgggcaggca ggctcttgct tctagaaacc agtgaagaca agtcagatcc agctcaatac
    14701 cgccgaatgc ttgaaaccct caaagcaaca gggatttttt cggtgatctc tggattattg
    14761 gttggaaagc cgatagacaa cagctactat gacgactata agcagcagct gctagctgtt
    14821 gttgataatg atatccccat tctttacaat gtcaatgttg gccatgctac cccaagagcc
    14881 attgttccct ttggtgtcat ggctgtggtt gatgccaaag agcaggtcat tcgatttgtc
    14941 cctgatgagc atacagacca aaatgacgtc taacaaatca aaacagaaag tgagagagtc
    15001 tatgccaaag gttgacacga taacgcaggt ttattttatc cgccacgcag agcctaacta
    15061 tcaaaaccac aacgacgtga ctagagagct ctccgagcat ggggttaagg cgagccaaga
    15121 cctggttagg caactagcag aggtgtcgat tgacgccttt tattccagtc cctataaacg
    15181 ctctattgac accattgccc cactagcagc tagtagggca atggaaatta agctgattga
    15241 cgatttgaga gagcgtaagc tagctgatgc ttggatagaa gactttgtcg acacagccaa
    15301 aaagcagtgg gacgatttta cctttaaatt gccgacaggc gaaagcctgc aagaggtaca
    15361 agacagaaat atagcagctc ttaaccgtat tttaaaagaa gcaaaaggca agacagtagt
    15421 cattggcaca catggcacag cactgtcaac ccttatcaac tactatcaac cagactttgg
    15481 ttttgaggat ttcgaccgat ataagcatgt ctttccttgg atagtcagag ctagctttga
    15541 tggtgacaag ctgcttgggc ttaatgagtt tctagtctga caagtctagc cttgatccag
    15601 ctattatagg tgatgacagc aacaaaatca gataattaac cctttcatta aaaaaaaaaa
    15661 aaacaaaacc tcggagacaa actagccagc agctatttct catgagtaat caacatgtta
    15721 aaatcttctt tggagatatt agacaaccat aattattata tcatcaaagg agagaaagat
    15781 gacaaacaaa acaaagcgta caggattggt acgcaagtac ggtgcctgct cagcagctat
    15841 cgccttagca gctcttgcaa gcctgggagc aggtaaagca gtaaaggcag accagccagc
    15901 agcactaaaa tatccagaac ctagagacta ttttcttcat actcgtgaag gtgatgttat
    15961 ttatgatgag gatataaaaa gatattttga ggatttagaa gcctatttaa cagctagact
    16021 tggtgggatt gataaaaaag tagaagaagc tgcccaaaag ccaggtattc caggtcctac
    16081 tggccctcaa ggtcctaagg gagacaaagg agatccaggt gcccctggtg agcgcggtcc
    16141 agctggacca aagggcgata cgggcgaagc cggaccaaga ggtgagcaag gcccagccgg
    16201 acaagctgga gaacgtggac caaaaggaga tccaggtgct ccaggtccta aaggtgaaaa
    16261 gggtgatact ggtgcagttg gtcctaaagg tgaaaaaggt gataccggag caaccggacc
    16321 aaagggagac aagggcgaac gcggtgaaaa aggcgagcaa ggccaacgtg gcgaaaaagg
    16381 cgagcaaggc caacgcggtg aaaaaggcga gcaaaaacca aagggtgatc aaggaaaaga
    16441 tacaaaacca tcagctccaa aagcacctga aaaggctcct gcaccaaaag ctccaaaggc
    16501 ttcagagcag tcatctaatc ctaaagcacc agctcctaag tcagcaccaa gcaaatcagc
    16561 ggcaccaaca ggtcaaaaag cagccctacc agcaacaggg gaaatcaacc acccattctt
    16621 cacccttgca gctcttagtg tcatcgctag cgtaggcgtc ctaactctaa aaggaaaaaa
    16681 agactaagct agttattgta tctttcctgt atgacactag ctaacagcta atcacaaaca
    16741 ccagagagag gtcttttctg acctctcttt tatatacact gagcacatgc ttacctcaaa
    16801 aagacagtag tctaagtttg actactgtct caaaaatcat ttttatctaa agctttgatc
    16861 agcttgacaa atggtagaga aggacttgat ttctaaggcc tttgacctca gtttgacttt
    16921 tgttaatttt ccttacgttt tatagctgct acaccagctg tagccataac tgcaagtgca
    16981 gctgcggtga agaatgggtt cacagcctca cctgttgctg gcaattgatt agtcgttttc
    17041 ttcatctcag ctttagctgc tgctgcttta gaagctgtgt gagctggcgc tgctacttta
    17101 cctgcttgat cagctttttc aggactgagt ggtttagcct ctggcttagt ttctggtttg
    17161 gtttctggaa ctttaggtgc gtcttcttgt ggttttgaat gtggacttga ttttttaata
    17221 tctttagcat ctagggcaac gcttctttcc tcacctgttg tagcttgaga aagctttttg
    17281 ccgttgacaa aaatctcata gaaagtgcca tctagaagcc ctttagaaaa tacagctttg
    17341 ccatcagctc ctgttgttac tttctctatc acacgaccta ctctatgctt tagagtgact
    17401 tcttgtcctg ataaaggttc agcatcttca ttacgaacga taacaaccaa aggtgtttta
    17461 ctgtattctg gctcaactgt tccttttccg tcaacagtaa agctagctga atgcttgtcg
    17521 ccatcaacac ctgttcgtac agtatagcct tgaggaacgc cattcacaaa aattgataaa
    17581 cttcttccta aaggaagctt gtcaaaaaca gcttgtcctt tttcatctgt tgtcacagtc
    17641 gcaagtgttt ttctgccact tgttatatct accacttgga cgtcttttcc agataatact
    17701 ttaccctcag ggtctataac tgttgcggta aaagcaaagc taccttcaat aacatcatca
    17761 tgatggtggt gtgcatgatc actgtgatga ctactctgcc catcgtcaaa aggcttagaa
    17821 acatcaatct tatccaataa aataacatga tgatgatcgt catgtggata catcaaggcc
    17881 ttaccctctg aagtatccaa taattgaatc ttgtctaatg gcaagcctgt atttttggcg
    17941 atataagctt tttttacggc aataatatct tcagctgatt gattagtgtc tagcggtaat
    18001 ttatcagctg ctgctacagg atttgcggtt tctgatgctt ttgtaattgg tttatcagcc
    18061 atcacctcag tgctgtcaga taactgttga ttagctgtat ctgcagtatc tttatcctca
    18121 cctaacctcg gttggactac agtgtgatta tccactgctg gtgattcatc agcaaatgct
    18181 actgacgagt tagttgacat cgctaaacca gcagccatta aagcagctgg gataagtaaa
    18241 gagtatcggg taacttgatt ctttttcatt aat
//
LOCUS       DARYXW010000037        18239 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.037, whole genome shotgun sequence.
ACCESSION   DARYXW010000037 DARYXW010000000
VERSION     DARYXW010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18239)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18239)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18239
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.037"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            345..1037
                     /gene="pyrF"
                     /locus_tag="TV191_001042"
     CDS             345..1037
                     /gene="pyrF"
                     /locus_tag="TV191_001042"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEL1507567.1"
                     /translation="MREERPIIALDFPSFEEVKSFLSLFPADERLYVKIGMELYYAEG
                     PDIVRYVKSLGHSVFLDLKLHDIPNTVKSTMAVLSRLGIDMTTVQAAGGVEMLRAARE
                     GLGQGPILIAVTQLTSTSEEQMREDQNIQSTLLASVLHYAKRTAQAKLDGVVCSAHEV
                     KAIKSEVPAGFVCLTPGIRPTGADIGDQKRVMTPHQARAIGSDYIVLGRPITQATDPV
                     KAYHQIKAEWNR"
     gene            1097..1732
                     /locus_tag="TV191_001043"
     CDS             1097..1732
                     /locus_tag="TV191_001043"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEL1507568.1"
                     /translation="MTLAAQIATDLLEIKAVYLRPKEPFTWASGITSPIYTDNRITLS
                     YPKTRSLIENGFVETIKAVFPEVEVIAGTATAGIPHGAIVADKMDLPFAYIRSKPKDH
                     GAGNQIEGHVRCGQKMVIIEDLISTGGSVLEAAAAASREGADVLGVVAIFTYELPVAS
                     INFEKAGLSLVTLSNYSDLIKVAKAKGYIDADGLALLKRFKEDQKHWQHES"
     gene            1784..2527
                     /locus_tag="TV191_001044"
     CDS             1784..2527
                     /locus_tag="TV191_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1507569.1"
                     /translation="MTYKDLLEIGETSYYQTDRLTYYKNPVVSERYFDNYLSYRSMPS
                     LADLKKDLAYVAKEQQDYPSHYAFLFFAENEELSTDMRAYLTDHHFSLEKHLIFTNEL
                     AKLHLKERDISPVTIEQLSETSFSAYLAYKYQANLAYGETYANQCKADNEANLLTNGS
                     TIYLAIKEGKIIGDITAWECGDYIEMDDFSVDEAYRGRGIGTALQRKASQGYKKVILI
                     SEEANRAMYEHQGYQEVAYYWTALKTSTR"
     gene            2762..4216
                     /locus_tag="TV191_001045"
     CDS             2762..4216
                     /locus_tag="TV191_001045"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HEL1507570.1"
                     /translation="MIFKDATEMAQAVREGRVSPSALVRDTIKKAQALNPELNAITSE
                     RFSEALAEAAARDFSGKPFAGVPIFLKDLGQEQEGQLATAGSVLFKDYRASKTDYVVQ
                     RLEELGFIILGRSNTPEFGFKNISDSRLHGPVNLPQDKSRNAGGSSGGAAALVSSGIT
                     LLAPASDGGGSIRIPASFNGLIGLKPSRGRVPVGPGSYRGWQGASVHFALTRSIRDTS
                     RLLYHLQVYQVESPFPLVPLTKEELFHPLDRPLRIALYDHMIDGTTASIDAQTALTEA
                     CHFLKEMGHEVVRLDKLPLDIPKVMRDYYLMTSVETAAMFADSQEALGRQVTKADMEV
                     MTWAIYQAGKDILASVYSQALQRWDHYSAEMASFHEQYDLLLTFTANTPAPKHGQFQP
                     SKELIDKLAKAECYPSSQRLALVEAMFEQSLFITPYTALANLTGQPALSLPTYETSAG
                     LPMGIQLIAAKGREDLLLGIARQFERAGLLKLPG"
     gene            4336..5202
                     /locus_tag="TV191_001046"
     CDS             4336..5202
                     /locus_tag="TV191_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEL1507571.1"
                     /translation="MKKGVALLSVSLASLLLAACGSQPSAQKTSWEKIKDKGVLKVAT
                     PATYQPTSYYNDANELVGYEVDLMKEIGKRLDLKVKFIETGYDQAFTSVDSGRVDVSL
                     NNFDITAKRQKKYNISTPYKYGVGGMIVRADGSSGISKADLSDWKGKKAAGASGTEYM
                     KVAKKQGAELVTYDNVTGDVYLNDVANGRTDFIPNDYPAQKLFVDYMKSQNPNLNVKM
                     SDVLYNPTAQGIIMSKKDDTLKKKIDAVIKDMKQDGSLKTISKTYYAGQDLTVPFGKD
                     KKIPVIDASDVD"
     gene            5230..5883
                     /locus_tag="TV191_001047"
     CDS             5230..5883
                     /locus_tag="TV191_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL1507572.1"
                     /translation="MLNLRLILESLGFVLSGLPYTLGISFLSFLTGLLLGLLLAFLRR
                     STSHFSHYLVRSYVSIMRGVPMIVVLFVLYFGLPYYGLELSALLCAYLGFSLVSAAYI
                     SEVFRASIDAIDQGQWEAARALGLPYVSIVKHVILPQAFRIAIPPLGNVVIDMVKSSS
                     LAAMITVPDIFQKAKIIGGREWDYMSMYILVAFIYWVIAFLLERCQGFLEKRLRLLS"
     gene            6014..6421
                     /locus_tag="TV191_001048"
     CDS             6014..6421
                     /locus_tag="TV191_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1507573.1"
                     /translation="MADSIVFRKNHMISTQAFARVLEASGIKRPTKDEARLSQMLKHS
                     NYLWTAWEGDKLVGVARALTDYAYVCYISDLAVDQAYQGQGIGKQLLSFISEDLGDAV
                     ALVLLSAPSAMSYYPKLGFEQSDKAFIIPRKPF"
     gene            6433..7086
                     /locus_tag="TV191_001049"
     CDS             6433..7086
                     /locus_tag="TV191_001049"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEL1507574.1"
                     /translation="MTHSAWHDEIKQVLPKDYYRRINRFLDEVYATGVVYPPRDNVFK
                     ALQVTPLEETRVLILGQDPYHGPLQAQGLSFSVPDSIPAPPSLQNILEELAADIGVRN
                     HHDLSSWAEQGVLLLNACLTVPEGRANGHAGLIWEPFTDAVIKVLNAKDRPVVFILWG
                     AYARRKKALITNPIHHVIESPHPSPLSAYRGFFGSKPFSRANAILEKEGLGQIDWLR"
     gene            7318..8592
                     /locus_tag="TV191_001050"
     CDS             7318..8592
                     /locus_tag="TV191_001050"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEL1507575.1"
                     /translation="MLLIKNGRVMDPKSQLDQVADVLIDNGRILRIAPDIEHDEVEQI
                     DASGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGVTTVVMMANTNPVISDTE
                     TLQAVLASAAKEKINIYTNASVTKRFNGQELTDFKALLAAGAVSFSDDGIPLESSKVL
                     KEALDLAKANKTFIALHEEDPQLNGVLGFNEHIAKDHFHFCGATGVAEYSMIARDVMI
                     AYDRQAHVHIQHLSKAESVKVVAFAQQLGAKVTAEATPQHFSKTEDLLRLAGANAKMN
                     PPLRTEQDRLAVIEGLKSGVIAIIATDHAPHHRDEKAVADLTKAPSGMTGLETSLSLG
                     LTNLVEPSHLSLMALLEKMTINPASLYSFDAGYLAESGPADLVIFADKEERLVTEAFA
                     SKASNSPFIGETLKGVVKYTIAKGQIVYQADN"
     gene            complement(8646..9293)
                     /gene="plsY"
                     /locus_tag="TV191_001051"
     CDS             complement(8646..9293)
                     /gene="plsY"
                     /locus_tag="TV191_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEL1507576.1"
                     /translation="MKLILLILTAYLLGSIPTGLWIGQYFYNINLREHGSGNTGTTNT
                     FRILGLKAGAATLLIDIFKGTLATLLPVLVGASNISPITIGFFAVLGHTFPIFAGFKG
                     GKAVATSAGVLLGFAPLYLLFLAAVFVLTLYLFSMISLASLTASVVAVISVLTFPAAH
                     FLLPSYDWLLTITIVVLAAIIILRHQDNMKRIKQQSENLIPWGLNLSKQQPASHH"
     gene            9426..11375
                     /gene="parE"
                     /locus_tag="TV191_001052"
     CDS             9426..11375
                     /gene="parE"
                     /locus_tag="TV191_001052"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEL1507577.1"
                     /translation="MAKKEISITNYNDDAIQVLEGLEAVRKRPGMYIGSTDATGLHHL
                     IWEIVDNAVDEALSGFGNEIDVTLNKDGSATISDSGRGMPTGQHALGIPTVQVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGRPVTGLE
                     KIATAPKSKSGTRVTFMPDDKIFSTTEFKWNTIAERLKESAFLLKTVKMTLTDLRGDD
                     PVVEEFHYENGVQDFVAYLNEDKETLTPVIYMEGQEQDFQVEVALQYNDGFSDNILSF
                     VNNVRTKDGGSHETGLKSAITKAMNDYARKTSLLKEKDKNLEGSDYREGLSAVLSILV
                     PEQHLQFEGQTKDKLGSPLARPIVESIVSEKLTFFLLENGELAGHLIRKAIKARDARE
                     AARRARDESRNGKKNKKDKGLLSGKLTPAQSKNPKKNELYLVEGDSAGGSAKQGRDRK
                     FQAILPLRGKVLNTEKAKMADILKNEEINTMVYTIGAGVGADFNLDDINYDKIIIMTD
                     ADTDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKSEKVSYAWTDGEL
                     EDLRKEFGKGASLQRYKGLGEMNADQLWETTMDPDTRTLIRVTIDDLARAERRVSVLM
                     GDKAAPRRQWIEDNVTFTLEENTVF"
     gene            11477..12292
                     /locus_tag="TV191_001053"
     CDS             11477..12292
                     /locus_tag="TV191_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATPase"
                     /protein_id="HEL1507578.1"
                     /translation="MKLDICQQSYSLQWGGTYYFALTDYPNIKAWELEKLAAFCAYEK
                     WNHRQTDISCQDSKLLEEVHQFLEAHACAYLFRPSCKLVASTFNINGEAVCCPYLSHT
                     CTVAAALSIFKTGRLLSAVRAFGVTAQELARSDRNAAGDPADYFHYVMLGWSNTTSGY
                     RLAMERLLNRMPNEKDLREHFVPGVSFHYSYSDICQMKGYVFDGYHPAKIKDELSLEE
                     LQACIIPKSWQQRFEAIIPKALRSRVHYLDYKGEGLVEWSDRVYQLLRVISDS"
     gene            12767..15226
                     /gene="parC"
                     /locus_tag="TV191_001054"
     CDS             12767..15226
                     /gene="parC"
                     /locus_tag="TV191_001054"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEL1507579.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQERALPDIRDGLKPVQRRI
                     LYSMNKDGNTFEKGYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQDWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIDKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSSGISAGYATDIPPHNLSEVIDAVIYMIDHPNAKLDKLMELLPGPDFPTGGI
                     IQGAAEIKKAYETGKSRVVVRSRTEIEDLKGGKQQIIVTELPYEVNKAVLVKKIDDVR
                     VNNKVPDIAEVRDESDRTGLRIAIELKKDADSQTILNYLLKYTELQVNYNFNMVAIDH
                     FTPRQVGLQKILSSYIAHRKSIIIKRSQFDKEKAEKRLHIVEGLIRVLSILDEIIALI
                     RASDNKADAKENLKVSYDFSEEQAEAIVTLQLYRLTNTDIVTLQQEEHDLRELITTLS
                     AIIGDEATMYNVMKRELREVKKKFAGPRLSELQAESQAIEIDSASLILEEETFVSVTQ
                     GGYIKRTSPRSFHASSLEEIGKRDDDHLIFVKQAKTTDHLLLFTNLGNVIYRPVYELT
                     DLRWKDIGEHLSQAIANFAADELVIYAELIQSFEEGLYISVTQHGLIKRFERKELTPW
                     RTYKSKSIKYAKLKDIDDRIVAIAPIIMEDLLLVTQQGYALRFSSQEIPIQGLKAAGV
                     KGINLKAQDYLVSACPVNADSFFVLTQRGALKRVAIADIPQTSRANRGLPVLRELKTK
                     PHRVFLAGMVKGDTTTGTIDLFTHDSEDTASDQQLEVISKTGQQYQLALNSLSLSDRT
                     SNGSFISESISDQEVAAARLI"
     gene            15324..16349
                     /locus_tag="TV191_001055"
     CDS             15324..16349
                     /locus_tag="TV191_001055"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEL1507580.1"
                     /translation="MMTTAIDWENLGFEYRKLPFRYVSYYKDGKWDAGRLTEDATLHI
                     SESAPALHYGQQAFEGLKAYRTKNGSIQLFRPDRNAARLQATADRLLMPQVSTEQFID
                     AVKQVVKANEDFVPPYGTGATLYLRPLLIGVGDIIGVKPANEYIFIVFAMPVGNYFKG
                     GLAPTNFIVSEDYDRAAPYGTGAAKVGGNYAGSLLPGKAAKTAGYSDVIYLDPATHTK
                     IEEVGAANFFGITANNEFITPLSPSILPSITKYSLLQLAEERLGMTAIEGDVPINDLD
                     RFVEAGACGTAAVISPIGGIQYQDKLHVFYSETEVGPVTRRLYDELVGIQFGDIEAPE
                     GWIVAID"
     gene            16417..16647
                     /locus_tag="TV191_001056"
     CDS             16417..16647
                     /locus_tag="TV191_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEL1507581.1"
                     /translation="MSKKEKKIELQLCDQQVTVNNTKIDGYQLQIGKRVVGEIAELDG
                     KFAVLKDSTVDAFFKTLEQAVENIIENYNLNH"
     gene            16708..16788
                     /locus_tag="TV191_001057"
     tRNA            16708..16788
                     /locus_tag="TV191_001057"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:16742..16744,aa:Tyr,seq:gta)
     gene            16827..16898
                     /locus_tag="TV191_001058"
     tRNA            16827..16898
                     /locus_tag="TV191_001058"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:16859..16861,aa:Gln,seq:ttg)
     gene            17026..18228
                     /gene="rpsA"
                     /locus_tag="TV191_001059"
     CDS             17026..18228
                     /gene="rpsA"
                     /locus_tag="TV191_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002997242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEL1507582.1"
                     /translation="MNEFEDLLNSVSEVNPGDVVTAEVLTVDNGQANVVIEGTGVEGV
                     LTLRELTNDREADINDYVKAGDTVEVLVLRQVVGKDTDTVTFLVSKKRLEARKAWDKL
                     IGREGEVVTVKGTRAVKGGLSVEFEGLRGFIPASMIDTRFVRNTEKFVGQEFDAKIKE
                     VDAAENRFILSRREVVEEAAKQARDKVFSTLSEGSVVTGTVARLTSFGAFIDLGGVDG
                     LVHVTELSHERNVSPKSVVSVGEEVEVKVLALDEEAGRVSLSLKATTPGPWDGVEQKL
                     AQGDVIEGKVKRLTDFGAFVEVLPGIDGLVHISQISHKRVENPKDVLTVGQEVTVKVL
                     DVNAADERVSLSIKALEERPAQAEGEKEEKRQSRPRHQKREAKRDYELPETQTGFSMA
                     DLFGDIEL"
BASE COUNT         5249 a         3512 c         4427 g         5051 t
ORIGIN      
        1 acattaacgt acagcaagct ttattttctt gctaaaaatc ttttttatac ctttgtcgtg
       61 tgagtaatgt caaaaccctt tgacaagggc tgtcaaaaaa gctataatga ttgagataag
      121 ttacctttaa gtgagtccag agaggcgagc aaggtacaca ggataagatg agagggtttg
      181 ctctcttgat tttcgtgtag cctcgcttct ttggaagtga ggcttttatg gtgtgacttt
      241 cagttggtct cgtggtaatg attcataaga ccaataaacc gctcgttaga cgggtgggca
      301 tgatttgttt gggagtaccc caagctgcat agaaaggata ggttatgcga gaagaacgcc
      361 ctattattgc cttagatttt ccttcctttg aggaggtcaa gtcatttctg tcgctgtttc
      421 cagctgatga gaggctatac gttaagattg gtatggaact gtattatgct gaaggaccag
      481 atattgtccg ttatgtcaag tccttaggtc acagtgtttt tctggatttg aagctgcatg
      541 atattccaaa tacagtcaaa tcaacgatgg cagtcctatc aaggcttggt atagacatga
      601 cgactgtgca ggctgctgga ggtgtagaga tgcttagagc agcgcgtgag ggcttggggc
      661 agggtccgat tctcattgcg gtgacacagc taacatcaac tagcgaagag caaatgcgtg
      721 aggatcaaaa cattcaatcc acgctgttag catctgtgct tcactatgcc aagcgtaccg
      781 ctcaggctaa gctagatggc gtggtttgct cagcccatga ggtcaaggcc attaagtcag
      841 aagtaccagc aggctttgtg tgtttgacac ctgggattcg cccgacaggt gctgacatcg
      901 gagatcaaaa gcgggtgatg acacctcatc aagctagagc tatcggaagt gactatattg
      961 ttcttggtcg tccgatcact caggctacag accctgtcaa ggcttatcac cagattaagg
     1021 cagagtggaa ccgttagcag caggatcatc atgacacata tagctggact atgacaccaa
     1081 ggaaaagagg agaaaaatga cactagcagc acaaattgca acagatttac ttgagattaa
     1141 ggccgtttac ctaagaccaa aggagccctt tacttgggcg tcaggcatta catcaccgat
     1201 ttatacggac aatcggatca ccctttctta tccaaaaacc agaagcttga ttgaaaatgg
     1261 ctttgtggag acgattaagg cagtatttcc agaggttgag gtgattgctg gcacagcaac
     1321 tgctggtatt ccacatggtg ctatcgttgc agataagatg gacctgcctt ttgcctatat
     1381 ccgcagcaag ccaaaggatc atggagcagg caaccaaata gaagggcatg tgcgctgcgg
     1441 gcaaaaaatg gtgattatcg aggatttgat ttcaacaggt ggatcagttc tggaggcggc
     1501 agcggcagct agtcgcgaag gtgctgatgt actaggagtg gtggcaattt ttacctatga
     1561 attgccagta gcaagcatca attttgaaaa ggcagggctt tccttggtga ccttgtctaa
     1621 ttattcagac ctcattaagg tcgctaaggc caagggctat attgatgctg atggcttggc
     1681 cctgttaaaa agatttaagg aggatcaaaa gcattggcag catgagagtt aaacagtgct
     1741 gaaaagctgc tgacatgctg actatgtctt aaggagagaa aaaatgactt acaaagattt
     1801 acttgagata ggtgagacca gttattatca gacggatcgc ttgacttact acaaaaatcc
     1861 tgtggtatct gagcgctatt ttgataatta ccttagctat cgtagcatgc cttctttggc
     1921 tgatttgaaa aaggacttgg cctatgtggc aaaagagcag caggattatc ctagtcacta
     1981 cgcctttctc ttttttgctg aaaatgaaga gctaagtaca gacatgcgag cttatttgac
     2041 agatcatcac tttagccttg aaaagcacct gatctttacc aatgagctgg caaagcttca
     2101 cctaaaggag cgtgatatat caccagtcac tattgaacag ctctcagaaa caagcttttc
     2161 tgcctatctg gcttacaaat atcaggctaa tttggcttat ggtgaaacct atgccaatca
     2221 atgcaaggct gataatgaag ccaatctatt gacaaacggc tcaaccattt atttagccat
     2281 caaggaaggg aagattatcg gagatattac ggcttgggaa tgtggcgact atattgaaat
     2341 ggacgatttc agtgtagatg aggcctatcg tggtcgtggt atcggtacag ccttacagcg
     2401 taaggccagt caaggctata agaaggtcat tctcatctca gaagaagcta atcgcgccat
     2461 gtatgagcac caaggctatc aggaggttgc ttactactgg acagcgctaa aaacatcgac
     2521 tagataagtg ataaagaaac agattatagg attgaaggtg taggctctta tgagtatgac
     2581 tcttcaatcc tttttttctg agcgcatttg ctaatcatac ctaatgaata agtcgtagcc
     2641 tgtctagtgg ctcattttaa tggcgtcttg ctctgtttta tgattaaata tagagaaaaa
     2701 gctattgtta gggcatgctt gttggtctag caaggctgat ggatgatagg atagggaatt
     2761 gatgattttt aaagatgcaa cagaaatggc gcaggctgtt cgagaaggta gggtgagccc
     2821 ctcagcctta gtgagagaca caattaaaaa ggctcaagca ctcaatcctg agttgaatgc
     2881 tattacctca gagcgttttt cagaagctct tgctgaggca gcagcaaggg atttttctgg
     2941 aaagccattt gctggtgtgc ctatttttct aaaggattta gggcaggagc aggagggcca
     3001 attggccact gcaggatcag tgttatttaa ggattatcgt gcctcaaaaa cggattatgt
     3061 tgtgcagcga ctagaggagc tgggctttat tattttagga agaagcaata cacctgaatt
     3121 tggctttaaa aatattagtg atagtcgctt acatggtccg gtaaatctgc cacaggacaa
     3181 gagccgtaat gctggtggtt catcaggtgg ggcagcagct cttgtgtcct caggaatcac
     3241 cttgctggct cctgctagtg acggaggagg atccattcgg attcctgcct cctttaatgg
     3301 cttgatcggt ttaaagccaa gcagaggaag agtgcctgtg gggccaggct cttatcgtgg
     3361 ctggcagggg gcgtctgttc attttgctct aacgaggtct attcgagaca caagtcgtct
     3421 tctttatcac ttgcaggttt atcaggtaga aagccctttt ccattagtgc cattaaccaa
     3481 agaagagctt tttcaccctt tagacagacc cttaaggatt gctctttatg atcacatgat
     3541 agatggaact accgcctcta tagatgctca gacagcttta accgaggcct gtcattttct
     3601 aaaagagatg gggcatgagg ttgtgcgatt agataagctt cctctagata taccaaaggt
     3661 tatgagggat tactacctga tgactagtgt tgagacagct gctatgtttg ctgatagcca
     3721 agaagccctt ggtcgtcagg tgaccaaagc agatatggag gtcatgacct gggctatcta
     3781 ccaagcgggt aaggatattc ttgcttcggt ctattctcag gcgctgcagc gctgggacca
     3841 ttatagtgct gaaatggcaa gctttcatga gcagtatgat cttttgctga cctttaccgc
     3901 caatacgcct gctccaaagc atggacagtt ccagccaagc aaggagctaa tagataagct
     3961 ggctaaggcg gaatgctacc cctccagtca gcgcctagcg ctagtagaag ccatgtttga
     4021 gcagagcttg ttcataaccc cttacacagc tttggcaaat ctgacaggcc aaccagctct
     4081 tagtttacca acctatgaaa cgtctgctgg attgccgatg ggcattcaat tgatagctgc
     4141 taaagggcga gaagacttat tgctgggaat agctagacag tttgaacggg ctggattgtt
     4201 aaagctacct ggttaaatat tataaaacag agctaatcta ttataggtta gcttttttgt
     4261 taaatcgagc atatctagtc tcttataaga ttagtcaatg ctatactgtc attaataatg
     4321 aaaaaggagt tcttgatgaa aaaaggagtt gctttacttt ctgttagctt ggcgagcttg
     4381 ctgttagccg cctgtgggtc acagccatca gctcaaaaaa caagctggga aaagattaaa
     4441 gataaaggtg ttttaaaggt tgctacgcct gcgacctacc agccaacatc gtactataat
     4501 gatgccaatg aattggtcgg ctatgaggtt gacctgatga aggaaattgg gaaacgcctt
     4561 gatcttaagg tgaagttcat tgaaacaggc tatgatcagg cttttacttc ggttgatagc
     4621 ggtcgtgttg atgtttctct caataatttt gacattacag ccaagcggca aaaaaaatac
     4681 aacatctcaa cgccttataa gtatggtgtt gggggaatga ttgttcgtgc tgatggcagc
     4741 tcaggcataa gcaaggctga cctaagcgat tggaaaggga aaaaagcagc tggcgcctct
     4801 ggtacagaat acatgaaggt tgccaagaag caaggtgctg aattagtcac ttatgataat
     4861 gtgacgggtg atgtttacct gaacgatgtt gctaatggca gaacagactt tattcccaat
     4921 gattatcctg cacaaaagct ttttgtggat tacatgaagt ctcaaaatcc taacctcaat
     4981 gtcaaaatga gtgatgtgct gtataatccg acagcacagg gcattatcat gagtaaaaaa
     5041 gatgacaccc ttaagaaaaa gattgatgcg gtcatcaaag acatgaaaca agatggcagc
     5101 ttgaaaacca tttcaaagac atactatgct ggtcaggatt tgacagttcc ttttggtaag
     5161 gacaagaaaa ttccagtcat tgatgccagt gatgtggact agtgccttag acaaaggagc
     5221 tctaaagcga tgcttaatct tagattgata ctagagagct tgggctttgt tttgtcaggt
     5281 ttgccctata ccttaggcat ttctttttta agctttctaa caggcctttt gctgggcttg
     5341 cttttagcct ttttaaggcg ttctactagt cactttagtc attatctggt caggagctat
     5401 gtgtccataa tgcgtggcgt tcctatgatt gtggtgctct ttgtccttta ttttgggctt
     5461 ccctattatg gcttagaact gtctgccttg ttatgtgcct atttgggctt ttcactggtt
     5521 agtgcagcct atatctctga ggtctttcgt gcctcgattg atgctattga tcagggacaa
     5581 tgggaggcag caagggcttt ggggctgcct tatgtcagca ttgtcaagca tgtgattctg
     5641 cctcaggcct ttcgtattgc tattccgcct ttaggaaatg ttgtgattga tatggtcaaa
     5701 agttcgtctt tggcagctat gattaccgtt cctgatattt ttcaaaaggc taaaattatt
     5761 ggtggcaggg agtgggatta catgtctatg tatatcttgg ttgcctttat ttattgggtg
     5821 attgcctttt tgctggagcg ctgtcagggc tttttagaaa agaggctgcg cttactctct
     5881 taaaaaccga atatttaccc tagaaatatt gtatttctag ggtttttatg ataaaaatat
     5941 gatagactaa agtagcctaa tcagttagtt agctttgtca agaactgact ggctagagtg
     6001 ttggaggtag gatatggcag actctattgt atttcggaaa aatcatatga tttcaactca
     6061 ggcctttgct cgagtgctgg aagcctcagg gattaaaaga ccgactaagg acgaggctag
     6121 attatcgcaa atgctaaagc attccaatta tctatggaca gcatgggaag gtgacaagtt
     6181 agttggtgtt gctagagccc ttactgacta tgcttatgtc tgctatattt ctgacctagc
     6241 agttgatcag gcatatcagg gtcaagggat aggcaagcaa ttgctgtctt ttatctcaga
     6301 ggatcttgga gatgctgttg ctcttgtatt gctgtcagca ccttcggcga tgtcctatta
     6361 ccctaagctt ggctttgaac aatcagacaa agccttcatt attccacgaa aaccgtttta
     6421 gagaggtatc taatgacaca ttcagcttgg catgatgaga ttaagcaagt gttacctaag
     6481 gattattatc ggcgtatcaa tcgcttttta gatgaggtct atgcgactgg agtggtttac
     6541 ccgcccagag acaatgtgtt taaggcctta caggtaacgc cattagaaga gacaagagtg
     6601 cttattttag ggcaggaccc ttatcatggc cctcttcaag ctcagggact ttccttttca
     6661 gtgcctgact ccattcctgc tccgccatct ttgcaaaata ttttggagga attagcagca
     6721 gatattggag taaggaatca tcacgatctt agcagctggg ctgagcaggg agtgttgctc
     6781 ttgaatgcct gcttgaccgt tccagaagga cgcgccaatg ggcatgcagg tctcatctgg
     6841 gagcccttta ccgatgcggt tataaaggtc ttgaatgcta aggataggcc tgttgtgttt
     6901 atcctctggg gagcctatgc gagaagaaag aaggccttga ttactaatcc gattcaccat
     6961 gttatcgaaa gccctcaccc tagccctctg tcagcctatc gtggcttttt tggcagcaag
     7021 cccttttcaa gagctaacgc cattttagaa aaagaaggcc taggacagat tgactggctg
     7081 cgctaggcat tgaggcaggc tattatggct aagcaggacg atttaccaat aaagtatccg
     7141 gctttggaga cttgggtata cctagctaaa tagagattga tgatatcagg gatcaagaca
     7201 gttacgtccg atatgtcaag caaaacaaat aatcactgcc tagataaatc agaaattgct
     7261 agggttatgc ttgattatcc tgataagcag ataagtagat ttgacatagg aggggtcatg
     7321 ttattaatta aaaatgggcg tgtgatggat ccaaaatcac agctagatca ggtggcagat
     7381 gtcttaattg ataatggaag gattttacgg attgctccag acattgagca tgatgaggta
     7441 gagcagatcg atgccagtgg acttgttgtt gctcctggtt tagtggatat tcatgttcat
     7501 tttagagagc cgggtcaaac gcacaaggag gacattcata caggtgctct ggcagcagct
     7561 gctggtgggg tgacaacagt agtcatgatg gcaaacacca atcctgttat atcagatacg
     7621 gaaaccttac aggctgttct agcaagtgct gctaaagaaa aaattaacat ttataccaat
     7681 gctagtgtga ccaagcggtt caatggccaa gagctaacag actttaaagc gctcttagca
     7741 gctggtgcgg tcagtttttc tgatgatggc attcctttag agagctccaa ggtcttaaag
     7801 gaagcattgg atttggctaa ggccaacaag accttcattg ccctgcatga ggaggatccc
     7861 caattaaacg gtgtccttgg cttcaatgag catatcgcta aggatcattt tcatttttgt
     7921 ggcgctactg gtgtggcaga atatagtatg attgccagag atgtgatgat tgcctatgat
     7981 cgacaagctc atgttcatat tcaacattta tctaaggctg agtctgttaa ggtagttgcc
     8041 tttgctcagc agttaggtgc caaggtcaca gccgaggcaa caccgcagca tttttctaaa
     8101 acagaagacc ttttacggct tgcaggggca aatgccaaga tgaatccgcc tctaagaaca
     8161 gaacaagata gattagcagt tattgagggg ctcaaatcag gtgtcatagc tattattgca
     8221 acggatcatg caccacatca tcgtgatgaa aaggccgttg ctgatctgac caaggcacca
     8281 tctggaatga ccggcttaga aacctcattg tcattaggcc tgacaaatct tgtggagccg
     8341 agccatcttt cattgatggc gttattagag aaaatgacca ttaatccagc ctcactatat
     8401 agctttgatg ctggttattt ggctgagtct ggccctgctg atcttgttat ttttgctgac
     8461 aaggaggagc gtttggtaac agaagccttt gcttcaaagg ctagtaattc accttttatt
     8521 ggcgaaaccc taaagggagt tgtgaaatac accattgcta agggacaaat tgtttatcag
     8581 gcagacaact aatcaacact taaaaagctg agcatctgat agtaactgat gctcagcttt
     8641 ttgatttagt gatggcttgc gggctgctgc ttgcttaagt tcaagcccca aggaatgaga
     8701 ttttcagatt gctgcttgat tcgcttcata ttatcctgat gccttaggat aatgattgct
     8761 gctagcacaa cgatggtaat ggttaatagc caatcgtagc taggcaataa aaagtgggcg
     8821 gcaggaaaag tcagaacgct aatcacagct actacagacg ctgttagact agctagtgaa
     8881 atcatgctaa ataaataaag cgttagcaca aacacagccg ctaaaaaaag gagatagagt
     8941 ggggcaaagc ctagcaagac accagcactg gttgcgactg cctttcctcc cttgaagcca
     9001 gcgaaaatag gaaaggtatg ccctaggaca gcaaaaaagc caatagtaat tggtgagata
     9061 ttgctagcgc caaccaaaac cggaagaagc gtggcaagcg tgcccttaaa aatatcaatc
     9121 aataaggttg cagcaccagc ttttagccca agaatccgaa acgtattggt cgtaccggta
     9181 ttacctgagc catgctcacg caggttgatg ttatagaaat actgtccaat ccataagcct
     9241 gttggaatgg agccaagtaa atatgctgta agaattaata ggatcaattt cataacatac
     9301 attatatcat aatgattgat ttaagcggaa gcagttacaa agaattacga aaaaatctta
     9361 aattattttg caaaattctc aaaaaacctg taagataaaa aagatgaaaa cgtctggagg
     9421 tcaacttggc taagaaagaa ataagcataa caaattataa tgatgatgcc attcaggtcc
     9481 tagagggctt agaggcagtt cgtaaaagac cagggatgta tatcggatca accgatgcaa
     9541 ccggacttca ccatttgatt tgggagattg tcgacaatgc tgttgacgag gccttatctg
     9601 gctttggaaa tgagatcgat gtgacgctaa acaaggatgg ttctgccacc atttctgaca
     9661 gcggacgagg catgccgacc ggacagcacg cccttggtat accaactgtt caggtcatct
     9721 ttaccatctt gcatgcaggt ggtaaatttg gtcaaggagg ctataaaacc tcaggaggcc
     9781 tgcatggtgt gggctcttca gttgtaaatg ccctatcgtc atggctagag gtggaaatca
     9841 cgagagacgg agcggtttac aagcagcgct ttgaaaatgg cggtaggcca gtgacaggct
     9901 tagaaaaaat agctacagct ccaaaaagca aatcagggac aagggttact ttcatgcctg
     9961 atgacaagat tttttcgaca actgagttca agtggaatac tatcgcagag cgtctaaagg
    10021 aatctgcttt tctgctaaag acggttaaaa tgaccctgac tgatctacga ggtgacgatc
    10081 cggtcgttga ggaatttcat tatgaaaatg gtgttcagga ttttgttgcc tatctcaatg
    10141 aggacaagga aaccttgact cctgtgattt acatggaagg gcaggagcag gattttcagg
    10201 ttgaggtcgc tttgcaatac aatgatgggt tttcagataa cattttgtcc tttgttaaca
    10261 atgttaggac aaaggacggt ggcagccatg aaactggctt aaaatcagct attacaaagg
    10321 ccatgaatga ctatgcccgc aaaaccagcc tactaaagga aaaggataaa aacttggagg
    10381 gctcagatta tcgtgagggc ttgtctgcag tgttatcgat ccttgtacca gagcagcatt
    10441 tgcaatttga agggcaaaca aaggacaagc taggaagccc actggcaagg ccgatcgttg
    10501 agagcattgt atcagaaaag ctgaccttct ttttacttga aaatggtgag ctggcaggtc
    10561 atttgattcg taaggctatc aaggcaagag acgcgcgtga ggcagccaga agagcgcgtg
    10621 atgagtctcg aaatggtaag aaaaacaaaa aggacaaggg gcttctttct gggaaattaa
    10681 ctccagccca gtccaaaaat cctaagaaaa acgagctgta cctagtcgag ggggactcag
    10741 ctggaggctc agctaagcag ggcagggatc gtaaatttca ggcaattctc cccttacgtg
    10801 gtaaggtttt gaacacagaa aaggccaaga tggctgatat tctcaaaaat gaggaaatca
    10861 atacaatggt ttataccatt ggcgcaggtg ttggtgctga tttcaatctt gatgatatta
    10921 attacgacaa gattattatc atgaccgatg ctgatacgga tggggctcat attcagaccc
    10981 tgctgctgac ctttttctac cgttatatgc ggccgctggt tgaagcagga catgtctata
    11041 ttgccttgcc tcctctttat aaaatgtcaa agggtaaagg caaatcggag aaggtttcct
    11101 atgcttggac agatggtgag ctggaggatc ttcgcaagga atttggtaaa ggtgcaagtc
    11161 tccaacgcta taagggactt ggggagatga atgccgatca gctatgggaa accacgatgg
    11221 accctgacac acgaaccctt atccgagtga cgattgatga cctggctagg gcagagcgac
    11281 gcgtttcagt cctcatggga gacaaggctg ccccacgccg tcaatggatt gaggacaatg
    11341 tcacctttac cttggaggaa aatacggttt tttaaggcat ttttcctaag gagggttcta
    11401 aaatatctca tatcaaattg ctattcatgt gctcagcatt catttatcaa ggattgtaat
    11461 cattgaggta acagtgatga agctagatat ttgtcaacaa agctacagtc ttcagtgggg
    11521 aggcacctat tattttgcat tgacagatta tcccaatatc aaggcttggg aactggaaaa
    11581 gctagcagcc ttttgtgcct acgaaaaatg gaatcatcgt caaacagaca ttagctgtca
    11641 ggacagcaag cttcttgaag aggttcatca atttcttgaa gcacatgctt gtgcctatct
    11701 ctttaggcct agctgtaaat tggtggcttc aacatttaac atcaatggag aggcagtctg
    11761 ttgtccttat ttaagtcata cctgcactgt agcggctgct ctaagcattt ttaagacagg
    11821 aaggctattg tctgctgtaa gagcttttgg ggtaacggca caggagttgg ctaggagtga
    11881 tcgaaatgct gctggtgatc ctgctgatta ttttcattat gtgatgcttg gctggtccaa
    11941 tacgacctca ggctatcgct tggctatgga gagattgctt aatcgtatgc caaatgaaaa
    12001 ggacttaaga gagcattttg tacccggagt tagctttcac tatagctatt ctgatatttg
    12061 tcagatgaaa ggctatgttt ttgatggcta tcaccctgcc aagatcaaag acgagcttag
    12121 tttggaggaa ttgcaggctt gcattattcc taaaagctgg cagcagcgct ttgaagcaat
    12181 tattccaaag gccttacgct caagggttca ttacctagac tataaaggcg aaggcttggt
    12241 cgagtggtct gatagggttt atcagctgtt aagagtgatc agtgacagct agctgtaaat
    12301 aggctagctt tatactattt tttgaatata atagacaatc taacagaaag gaaagctcag
    12361 tgagaggtct cttgctgggt gtgggatgga tttcctagaa actgctaatc ctagcgatag
    12421 gggagcgtag cgagcccatt ctgaaagctc ctgccgtagt gaaaagaaga taatcgctta
    12481 cgattatctt cgagggaaat ttcgagccga agtctcgaaa tttaggaatg gaaccgtagg
    12541 ttcgcttctg tccccactac ctaaaggaac tttcaaaaaa aactaattaa agaaagagat
    12601 atctttctga aagaaacaaa gaaaggaatg ttcagctagt ttactaactg aacacgggac
    12661 tatttttcct agaaaaatcg gtaacctcct agtgtccaag gacacgtcgt cagttccagc
    12721 attttttacg gaaaaatttc gcaagcgaaa cgtccctttg tatcttatga gtaatattca
    12781 aaacatgtcc cttgaggaca tcatgggaga gcgttttgga cgctactcca aatacatcat
    12841 tcaggagcga gcgcttcctg atattcgaga tggtctaaag cctgttcagc gccgcattct
    12901 ttattctatg aataaggacg gtaatacctt tgaaaagggc taccgcaagt cagccaagtc
    12961 tgttggtaat atcatgggca atttccaccc gcatggagat tcttcgatct atgacgctat
    13021 ggtacgcatg agtcaggatt ggaagaatcg tgaaattctt gtggaaatgc atggcaataa
    13081 cggctcgatg gacggtgatc caccggcagc tatgcggtac actgaggcaa gattatctga
    13141 aattgctggt tacctgctac aggacatcga taaaaaaaca gtgccatttg cttggaattt
    13201 tgacgatacc gaaaaagagc caacagtatt gccagctgcc tttccaaatc tattggtcaa
    13261 tggctcatca gggatctcag caggctatgc tacagatatt ccaccacata atttgtcaga
    13321 ggtgatcgat gctgttattt atatgattga ccacccaaat gccaagctgg ataagttaat
    13381 ggagctattg ccgggtcctg attttccaac aggtggtatt atccaaggag cagccgaaat
    13441 taaaaaagcc tacgaaacag gtaagagccg cgttgttgtt cgctccagaa ctgaaattga
    13501 ggatctaaag ggaggcaagc agcagatcat tgtgaccgaa cttccttatg aggtcaataa
    13561 agctgtccta gttaaaaaaa ttgatgatgt tcgggttaat aacaaggttc cagacatagc
    13621 agaggtgcgt gatgagtcag accgtacagg gctacgcatt gctattgagc tcaaaaaaga
    13681 cgctgacagc caaaccatct tgaattattt gttgaagtat accgagcttc aagtcaatta
    13741 taattttaat atggttgcga ttgatcattt tacgcctcgt caggttggat tgcaaaaaat
    13801 cttatcaagc tatatcgctc accgcaaaag tattattatc aagcgctctc agtttgacaa
    13861 ggaaaaggct gaaaagagat tgcatattgt tgagggcttg atacgtgtct tatctatttt
    13921 agatgagatt atcgcgctga tccgagcttc tgacaataag gctgacgcca aggaaaacct
    13981 aaaggtcagc tatgattttt cagaggaaca agcagaggct atcgtaacct tacagcttta
    14041 tcgactgacc aatacagata ttgttaccct ccagcaggaa gaacatgacc taagagagct
    14101 catcacaact ctctctgcca ttattggtga tgaagcaacc atgtataacg tgatgaagcg
    14161 tgagctaaga gaggtcaaga aaaagtttgc agggccgcgt ttatcagagc tgcaggctga
    14221 aagccaagcg attgaaattg attctgctag tcttattttg gaggaagaaa cctttgtcag
    14281 tgtgactcag ggaggctata tcaagcgaac aagccctagg tcatttcacg cctcaagcct
    14341 tgaggaaatt ggtaagcgtg atgatgatca tctgatcttt gttaagcagg ctaagacaac
    14401 agaccacctg ttactcttta ctaatttagg taatgttatt taccgtccgg tctatgagct
    14461 gactgacttg cgctggaagg acatcgggga gcatttatca caggctattg ctaattttgc
    14521 tgctgatgag ctggtgatat atgctgagtt gatccagtcc tttgaagagg gactatatat
    14581 ctcagtgaca cagcatggac tgattaaacg gtttgagcgc aaggagctga cgccttggcg
    14641 aacctacaaa tcaaaatcaa ttaaatacgc caagctaaaa gacatagatg atcgcattgt
    14701 ggcaatagca ccaattatca tggaagatct tcttttggtg acgcagcagg gctacgcctt
    14761 gcggttttct agccaagaaa taccgattca gggcctaaag gctgccggag ttaaaggaat
    14821 taacctaaag gctcaggatt acttggtttc tgcctgccca gtcaatgctg attccttctt
    14881 tgtgctgacg caaagaggag cactaaagcg agtggcgatt gctgatattc cacagaccag
    14941 ccgagctaac agaggtctgc cggtgttacg agaattaaag accaagccac acagagtttt
    15001 cttggcagga atggtaaaag gagatactac aacaggtacc attgacttat ttacacatga
    15061 ttcagaggac acagctagtg accagcaatt agaggttatt agtaagactg gtcaacaata
    15121 ccagcttgct ctcaatagcc tgtctctatc agataggaca agtaatggct cctttatttc
    15181 agagagcatt tcagatcagg aggtcgctgc tgcaaggctc atctagccaa agctttttcg
    15241 ctgtaccagt gagggctctg agtctttcat cgaaaaaaga tgcaaaacaa tgaagaaaag
    15301 aatacaaaaa gaaaagaggt aggataatga caacagctat tgattgggaa aacttaggct
    15361 ttgaataccg taagctgcca tttcgctatg tatcatatta caaggacggc aaatgggacg
    15421 caggtcgctt aacagaagat gctaccctgc acatctcaga aagtgcacca gctctgcatt
    15481 atgggcaaca agcctttgaa ggcttaaagg cctatcgcac taagaacggc tctattcagc
    15541 tatttcgccc agaccgcaat gcagctcgct tacaggcaac agctgaccgt ttgctgatgc
    15601 cacaggtatc taccgagcaa ttcattgacg ccgttaagca agtggtaaag gcaaatgagg
    15661 attttgtacc gccatatgga actggtgcta ccctttacct tagacccttg ttaattggtg
    15721 ttggcgatat tatcggtgtt aagcctgcta acgaatatat atttatagtt tttgccatgc
    15781 ctgttggcaa ttactttaaa ggcgggcttg cgccgaccaa ctttatcgtc tctgaggatt
    15841 atgatagagc agctccttat ggcactggag ctgccaaggt tggtgggaac tatgcaggta
    15901 gcttattgcc aggaaaagca gctaagacag cagggtattc agatgtgatt tacctagatc
    15961 cagcaactca cactaagatt gaagaggtcg gagccgctaa tttctttggc atcactgcca
    16021 ataatgaatt tattacgccg cttagcccat caatcttgcc ttcaattacc aaatactcct
    16081 tactccaatt agccgaagaa aggcttggta tgaccgctat tgagggtgat gtgccgatta
    16141 atgatttgga ccgatttgtt gaggcaggag cttgtgggac agctgctgtg atctcaccaa
    16201 ttggaggcat tcagtatcag gataagctac atgtctttta cagcgagact gaggttggtc
    16261 cagtgacacg tcgattatac gatgagctgg tcggtatcca attcggtgat atcgaagcac
    16321 cagaaggctg gattgtagct attgattaaa ataagtgaag cttgctattg caagctcttt
    16381 tgattttgtg taaaatagac aaggcgaggt gaagtgatga gtaaaaaaga gaaaaaaatt
    16441 gaactgcaat tatgcgatca acaagtaaca gtcaacaata ccaagataga cggttatcag
    16501 ttacaaattg gcaagcgtgt cgttggcgag attgcagagc ttgatggcaa gtttgctgtc
    16561 ttaaaagaca gcacagtaga tgcttttttt aaaacattag agcaagcagt tgaaaatatt
    16621 attgaaaact ataatttgaa ccactaaaaa tgcttaaaaa gacttgtcag cttacaaaaa
    16681 ctatggtaga atagtttttg ttgttacgga aagatagcga agaggctaaa cgcggcggac
    16741 tgtaaatccg ctcctttggg ttcgggggtt cgaatccctc tctttccatg cctaagctat
    16801 taggttcatt gttttaatga tgatattggg gtatagccaa gcggtaaggc aagggacttt
    16861 gactccctca tgcgttggtt cgaatccagc taccccagtc agaggtatca gattagcgtc
    16921 tgagatcgtc aaggataaaa gttgttgtca ttgcgggtta ccttgagaaa atatattgtt
    16981 atcaaaagct agcataagct agcttttgtt ggaggatttt ttagaatgaa tgaatttgaa
    17041 gatttgctaa acagtgttag cgaagtcaat cctggtgatg ttgtcactgc ggaggttttg
    17101 acagttgata acggtcaagc aaacgttgtt attgaaggca caggtgttga aggcgttttg
    17161 acacttcgtg aattgactaa cgatcgtgaa gctgatatta atgactatgt taaagctggc
    17221 gacaccgttg aagtgcttgt tcttcgtcaa gttgtaggta aagatactga tacagttact
    17281 ttcctagtat ctaaaaaacg tttggaagct cgtaaggcat gggacaagct tattggtcgt
    17341 gaaggtgaag tcgttactgt taaggggact cgtgctgtta aaggtggact ttcagttgaa
    17401 tttgaagggc ttcgcggatt tatccctgct tcaatgattg acactcgttt tgttcgcaat
    17461 acagaaaagt ttgtcggtca agaatttgac gctaaaatca aagaagttga tgcagcagaa
    17521 aaccgcttta tcttatcacg tcgtgaggtt gttgaagaag cagctaagca agcacgtgac
    17581 aaagtctttt caacactttc agaaggttca gtggtaactg gtactgttgc gcgtttgaca
    17641 agctttggtg cttttattga tcttggtggt gttgacggtc ttgttcacgt aactgagctc
    17701 tcacatgagc gtaatgtgtc gcctaaatca gttgtttctg ttggtgaaga ggttgaggtg
    17761 aaggtacttg ctcttgatga ggaagcaggt cgcgtatcac tatcacttaa agcaacaaca
    17821 cctggacctt gggatggcgt tgagcaaaag cttgcacaag gtgatgttat cgaaggtaag
    17881 gttaagcgct tgactgactt tggtgctttt gttgaggtat tacctggaat tgatggactt
    17941 gtacacattt cacaaatctc acacaagcgt gttgaaaatc caaaggacgt gcttactgta
    18001 ggtcaagagg taactgttaa ggttcttgac gttaacgctg ctgatgagcg tgtatcattg
    18061 tcaatcaagg cacttgaaga gcgtccagca caagcagagg gtgaaaagga agaaaaacgt
    18121 caatcacgtc cacgtcatca aaaacgtgaa gctaagcgtg attatgagct tccagaaaca
    18181 caaactggat tttcaatggc tgaccttttt ggtgatattg aattataata ctataaaaa
//
LOCUS       DARYXW010000038        18128 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.038, whole genome shotgun sequence.
ACCESSION   DARYXW010000038 DARYXW010000000
VERSION     DARYXW010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18128)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18128)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18128
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.038"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            71..1321
                     /locus_tag="TV191_001060"
     CDS             71..1321
                     /locus_tag="TV191_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEL1507583.1"
                     /translation="MKELKCPHCHTLFTVNESDYSQILAQVRGQEFDKELAQRLESEM
                     KLQEARANNRFQEVLTKKEQAIQSLTNRLERIEQEQAYLRQQELAQKDKELLELHNQL
                     DKLELEQQSRLQSALTVVEKERDHLKNQLVLQEKESELSLASVRSDYEVQLKAVNEQV
                     EFYKNFKAQQSTKAIGESLELYAETEFNKVRSYAFPNASFTKDNQVSHRGSKGDYIYR
                     ELDNNGVEILSIMFEMKNEVDTTKTKHKNSDFFKELDKDRREKNCEYAVLVTMLEADN
                     DYYNAGIVDVSHDYDKMYVVRPQLFIHLIGLLRNAALNSLKYKQELALVREQHIDITH
                     FEEDLEHFKHAFAKNYQSASNNFKKAVDEIDKSIKRMEEVKRFLTTSENQLRLANNKL
                     DDVSVKKLTRNNPTMRDKFQAIKP"
     gene            1430..2311
                     /gene="truB"
                     /locus_tag="TV191_001061"
     CDS             1430..2311
                     /gene="truB"
                     /locus_tag="TV191_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002271102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEL1507584.1"
                     /translation="MINGIINLKKEAGMTSHDAVFKLRKLLQEKKIGHGGTLDPDVVG
                     VLPIAVGKATRVIEYMTEAGKTYEGEVTLGYSTTTEDASGEIVDQTVVPLSLTEAMVD
                     EAMTQFIGQMTQIPPMYSAVKVNGRKLYDYARAGEAVERPKRQVTIDQFERTSPLTFA
                     GGLCRFSFRVSCSKGTYIRTLAVDLGRMLGYASHMSWLVRTASSGLSLDQSYTLSEIA
                     ELLDKKDMSFLLPIEYGVSDLARVVVNDWELRELSFGRKIALSCEENLLAAFYQDSLI
                     AILEKQEGLYKPRKVFI"
     gene            2325..3257
                     /locus_tag="TV191_001062"
     CDS             2325..3257
                     /locus_tag="TV191_001062"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEL1507585.1"
                     /translation="MDIQHIKSYQEIDESADTVLVLGYFDGLHRGHKALFDKAKEISR
                     QESLKIVTLTFHESPQLAFTRFSPDFLRHITYPEKRYEKFAEYGVDKLYLLDFTTSFS
                     KLSSDDFIDHYIGRLRVRHIVVGFDYHFGCDHADSHYLAKRIKGTVYSISEVKEDQIK
                     ISSTRIRSLITAGDVAKANQLLGYELSTRGMVVHGDARGRTIGFPTANLAPIDRTYLP
                     ADGVYVTDVLVRGKRYRSMTSIGKNITFGGKELRLEANIFDFNEDIYGETLEIIWLDR
                     IREMNKFSDVSTFISQLKQDKEAAINWKKDSQGY"
     gene            3300..3704
                     /locus_tag="TV191_001063"
     CDS             3300..3704
                     /locus_tag="TV191_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEL1507586.1"
                     /translation="MITLFLSPSCTSCRKARAWLTKHDVDFQEHNIITSPLSREELLA
                     ILSFTENGTEDIISTRSKVFQKLDIDIDELSIMDLIDLIAKNPSLLRRPIIMDSKRMQ
                     IGFNEDEIRAFLPRDYRKQELRQATIKAEIEG"
     gene            3706..3984
                     /locus_tag="TV191_001064"
     CDS             3706..3984
                     /locus_tag="TV191_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEL1507587.1"
                     /translation="MSDHYHYPLDVSWSTEEITSVLHFLNQVELAYEAKVGAEELLKS
                     YAAYKEIVRSKSQEKQIDREFQQASGYSTYQAVKKAREIEKGFFSLGR"
     gene            3974..4750
                     /locus_tag="TV191_001065"
     CDS             3974..4750
                     /locus_tag="TV191_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEL1507588.1"
                     /translation="MEDKYAFAKTIIKEAGLLIKDRMKDSLAIEIKTQHDDLVTNVDQ
                     ETQDFLIAKIKQAYPSDHMIAEEGGICHAITDGKVWVLDPIDGTVNFIVQKANFAIMM
                     AYYENGVGKFSLIYDVMADQLFSGGGDFAVTLNDQVLASYQDKPLDRSLIGCNAGMLS
                     RNDYNLHQLIDQTLGVRVYGGAGICMTKVLRQQLMAYFSYIQPWDYAAAAIMGESLGY
                     VLLTLEGKQPDFQSRQKVMFVPKSKLATIQSLLKTNENTQ"
     gene            4767..6074
                     /locus_tag="TV191_001066"
     CDS             4767..6074
                     /locus_tag="TV191_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEL1507589.1"
                     /translation="MQLPNDFIEKYQQLLGSEAKAFFESFDQPAISAYRINPLKHQSV
                     CLDPPIPDTPWGYYGRVSGKSPNHVSGVVYSQEPAAQMVAQVASPAKGTRVLDLAAAP
                     GGKSTQLLAYLENTGLLVSNEISTKRSKALVENIERFGARNVIVTNESADRLAAVFPE
                     YFDTIVFDGPCSGEGMFRKDPNAVSYWHKDYPAACASLQRSILAEAIPMLKPGGQLIY
                     STCTWSPEENEEVVRWLLESYDFLELEHIPKINGMAEGIGMPQAARMYPHRFKGEGQF
                     VAKLKDTRSTISSSSYKSPRSNLTQEQLRLWQDFEKNHLNITLSGLLQVFGDRLYLLP
                     DGLPCLRSLKIARNGLELGTFKKKRFEPSYALGLALRPEEVSLSVEINEEDFVTYASG
                     NTITLPESYATDWYQLVINGNGLGFAKIVGRTLKNSFPKGLRF"
     gene            6212..7078
                     /locus_tag="TV191_001067"
     CDS             6212..7078
                     /locus_tag="TV191_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HEL1507590.1"
                     /translation="MKSKKKFFLLSLLALSAFFLSACSSWIDKGESITAVGSTALQPL
                     VEAAADEFGSNNLGKSVNVQGGGSGTGLSQVQSGAVQVGNSDVFAEEKDGIDAAKLVD
                     HQVAVAGLAVIANPKVKVSNLTSKQLQKIFSGEYTNWKQVGGQDLAISVINRAASSGS
                     RATFDSVIMKGVTAKQSQEQDSNGMVKSIVSQTPGAISYLSFAYVDSSVKSLRLNGFK
                     ANAKNVATNDWPIWSYEHMYTKGKPDGLTKEFLDYVLSDEVQKTIVTHMGYIAITDMK
                     VVKSYDGKVTDK"
     gene            7089..8024
                     /gene="pstC"
                     /locus_tag="TV191_001068"
     CDS             7089..8024
                     /gene="pstC"
                     /locus_tag="TV191_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEL1507591.1"
                     /translation="MKNQELAKQLASPSKNSRLEAFGRTITFFCLALIVFIVAMILLF
                     VAQKGLSTFFVNKVNLFDFLFGTEWQPSVKNAAGVPYLGALPMIAGSFLVTILSALVA
                     TPFAIGAAVFMTEISPKYGAKLLQPAVELLVGIPSVVYGFIGLQVVVPFIRSIFGGTG
                     FGILSGVCVLFVMILPTVTFMTTDSLRAVPRHYREASMAMGATRWQTIWRVVLNAARP
                     GIFTAVIFGMARAFGEALAIQMVVGNSAVMPASLTTPAATLTSVLTMGIGNTVMGTVQ
                     NNVLWSLALVLLLMSLAFNSLVKLITKERKRNYER"
     gene            8014..8901
                     /gene="pstA"
                     /locus_tag="TV191_001069"
     CDS             8014..8901
                     /gene="pstA"
                     /locus_tag="TV191_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEL1507592.1"
                     /translation="MNAKKVDKVATGSLYTIAGIIVAILASLILFILVRGLPHISWSF
                     LTGKSSSYEAGGGIGIQLYNSFFLLVVTLIISIPLSTGAGIYLAEYAKKGPVTNVIRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLLHVH
                     HTQREAGLALGLSRWETVFHVVIPEALPSIVTGIVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNPLSVTSPISIFRQSETLAVHIWKVNSEGTIPDATLVSAGSAAVLLIFILIF
                     NLSARFIGKRIHAKMTAAK"
     gene            8918..9721
                     /gene="pstB"
                     /locus_tag="TV191_001070"
     CDS             8918..9721
                     /gene="pstB"
                     /locus_tag="TV191_001070"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEL1507593.1"
                     /translation="MTEYNWNERHIITFPEETIALATKDLHVYYGSKEAIKGIDMQFE
                     KNKITALIGPSGCGKSTYLRSLNRMNDTIDIARVTGEILYQGIDVNRKDMNVYEIRKH
                     LGMVFQRPNPFAKSIYKNITFAHERAGVRDKRVLDEIVETSLKQAALWDQVKDDLHKS
                     AFTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKDYTIIIV
                     THNMQQAARASDYTAFFYLGDLIEYDKTRNIFQNATCQSTNDYVSGHFG"
     gene            9735..10493
                     /gene="pstB"
                     /locus_tag="TV191_001071"
     CDS             9735..10493
                     /gene="pstB"
                     /locus_tag="TV191_001071"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEL1507594.1"
                     /translation="MAEPILQIRDLSVYYNKKKTLKDVSLDFYPNEITALIGPSGSGK
                     STLLRSINRMNDLNPEVTITGSIVYNGHNIYSPRTDTVDLRKEIGMVFQQPNPFPMSI
                     YENVVYGLRLKGIRDKAVLDHAVESSLKGASIWSEVKDRLHDSAVGLSGGQQQRVCIA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLFSLKKDYTMVIVTRSMQQASRLSDRTG
                     FFLEGDLLEFGPTKAMFMNPKRKETEDYISGKFG"
     gene            10564..11217
                     /gene="phoU"
                     /locus_tag="TV191_001072"
     CDS             10564..11217
                     /gene="phoU"
                     /locus_tag="TV191_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEL1507595.1"
                     /translation="MLRTKFEEELDKLHNQFYSMGTEVLSQINKTVRAFVSHDRELAK
                     EVIEEDDTINGFETKLEKKSLEIIALQQPVSNDLRTVITVLKASSDIERMGDHAASIA
                     KATIRMKGEERIPIVEEHINLMGKAVKQMVEEALNAYINADDAKAYEIAASDEIIDNY
                     FREIQSLAVEEIRKTPDAVFAGKEYFQVLMYLERIGDYARNICEWIVYLKTGKIIEL"
     gene            11451..13988
                     /locus_tag="TV191_001073"
     CDS             11451..13988
                     /locus_tag="TV191_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEL1507596.1"
                     /translation="MKKVEHLIEKFIPENYNIFLDINRSTKTFTGNVAINGEALDNQV
                     SFHQKDLAINAILLDNEAVSYHVDDDNELVRVELPETGMMTLVIEFSGNITDNMTGIY
                     PSYYTKDGEKQEVISTQFESHFAREAFPCIDEPEAKATFDLSLTFDQAEGEIALSNMP
                     EVNAERRKETGLWTFETTPRMSSYLLAFALGDLHGKTTKSKNGTTVGVYATKAHPLTS
                     LDFSLDIAVRVIDFYEDYFGVRYPIPQSLNIALPDFSSGAMENWGLITYREIYLLVDG
                     NSTARSRQNVALVVAHEIAHQWFGNLVTMKWWDDLWLNESFANMMEYVAINAIEPSWR
                     IFEDFQTTGVPLALKRDATDGVQSVHVAVNHPDEINTLFDPAIVYAKGSRLMHMLRRW
                     IGDKDFAAGLRLYFEKHQYRNTVGRDLWQALSEASGKDVAAFMDAWLEQPGYPVLTAR
                     VDNDQLILSQKQFFIGEASDQKRLWPIPLNANWKGLPDVLTEESIVISGFSQLAAQNK
                     GTLRFNTENTAHYITDYQGQLFHSLVDDLKHLDNTSALQVIQERRLLADSGLISYAEL
                     VDLIAQLDDKKSYMVAAAVQQVIRGLEQFIDEGTSAEQSFNRLISSIFQEDFRQLGFE
                     KRANESDEDEMVRQIALHHLLVGGNRDVIKQAKTIFEAYANRIEAIPAAIRRSVLVSQ
                     IKYFEIADLVDAYFDAYVATKDNNLRADLSAALATTANPSTLKRIQYSLKDKDIIKPQ
                     DLAAWYSFLLDQASAQESIWRWARENWKWIKASLGGDMSFDKFIIYPANHFKTAERLA
                     EYKAFFEPQLDDMAISRNISMGINEISARVALIDSEKEAIANALSQY"
     gene            14407..15081
                     /locus_tag="TV191_001074"
     CDS             14407..15081
                     /locus_tag="TV191_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1507597.1"
                     /translation="MIKLLLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGI
                     YDLILLDLMLPEKDGFQVLKALREKDIKIPVLIMTAKESIDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRVGKFNDKSLKFGNLTVDTTRKEVQVNGQAIELLGKELDLLIY
                     ILQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTDFVNHLQTLRSVGY
                     ILKANE"
     gene            15074..16384
                     /locus_tag="TV191_001075"
     CDS             15074..16384
                     /locus_tag="TV191_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEL1507598.1"
                     /translation="MNKLKKGLLSDNYTHFFHFFAIFTGIFVVMTIIILQIMRFSVYS
                     TVDSSLISVSQNASNYANRTMARISSFYFDAENNLIQALPELEASKSLGSSTTNMDII
                     LFSANGTILNSFDAFSNYQSFRLDKSQLNNIVTTQLMNFYGQKEKYHTLTVKVHIKNY
                     PAVAYMMAVVNVQQLDTANERYEQIIIMVMIVFWLISILASIYLAKWSRKPIMESYAK
                     QKMFVENASHELRTPLAVLQNRLESLFRKPNETILDNSEHIASSLDEVRNMRILTTNL
                     LNLARSDDGIKPQLVDVDAAFFDTVFENYQLVAEESGKQFISVNQINRPLKTDKALLK
                     QLMTILFDNAIKYTDHNGVVEVKVRTTDKHLLISVIDNGPGIKDDDKKKIFDRFYRVD
                     KARARQKGGFGLGLALAQQIVTSLKGTITVSDNKPTGAIFEVKL"
     gene            16769..17188
                     /locus_tag="TV191_001076"
     CDS             16769..17188
                     /locus_tag="TV191_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507599.1"
                     /translation="MIVYLKQHKNYWKLVSIAALIIILGGILTMNWLNGEELKKKKYR
                     QEQDRVVKYIGEHIELCNGQPITKIEFIEFQLETATTGTWSITTIVNEKYLIHFSEDR
                     LGEEIRTSYYSPKEFKQYSEKMRNNMTNVETIYYEEK"
     gene            17185..>18128
                     /locus_tag="TV191_001077"
     CDS             17185..>18128
                     /locus_tag="TV191_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507600.1"
                     /translation="MMIDRDYKNISEDVYKVDSGKERDPIQEGYPVANGKYRVLEAED
                     NPDNGMQAMAVVPIKDGKEDRSHIVIAYAGTNSSDIRDIDTDIQSVVFGDDQYLCTHE
                     EPDSFKVVKSQLSTAKAFSDYIRTSYPNAAISYTGHSLGGYLALITAAHAKQPATVFN
                     APSSVNNLSKEAIDFVKANKGLYHSYRINNDYIGNLGTYFGDDELGISRWVDGKAGIG
                     RHSLAAYRFNSKGQVIDRKGRPAAAQAPALATLSSKLTEYRLLKKKYVASNGISSSEE
                     FYLDQFQARAVAQALEQTTQLAQEEIIARRKEAVAEAEA"
BASE COUNT         5426 a         3360 c         4073 g         5269 t
ORIGIN      
        1 tctggaaaaa tcattttcta ggcttttttt gctataatgg cagtgagata attgcaagaa
       61 tggagaaatc atgaaagaac taaaatgtcc tcattgccat accttattta cggtcaatga
      121 gtctgactat agtcagattt tagcacaggt acgaggtcaa gagtttgaca aggagttggc
      181 acagcgctta gaaagtgaga tgaagctgca agaagcaagg gccaataacc gcttccaaga
      241 ggtgcttact aaaaaggagc aggctattca aagcctgacc aaccgcttgg agcgtattga
      301 gcaggaacag gcctatttga ggcaacagga gctagcccaa aaggataaag agctcctaga
      361 gcttcacaat cagctagata agctagagct tgagcagcaa tcaaggctcc agtctgccct
      421 tacagttgtt gaaaaggaac gtgatcacct aaaaaatcag ctcgtgctgc aggaaaaaga
      481 aagcgaactt tctctagcct ctgtgcgcag tgattatgag gtgcagttaa aggctgtcaa
      541 tgagcaggtt gagttttaca agaattttaa agcgcagcag tcaactaaag ctattggaga
      601 gagcttagag ctgtatgccg aaaccgagtt taacaaggtt cgcagctatg cctttccaaa
      661 tgccagtttt accaaggaca atcaagtgtc tcatcgaggc tcaaagggtg attatattta
      721 ccgagagcta gacaataatg gtgttgaaat tctctcaatc atgtttgaaa tgaaaaatga
      781 ggttgacacg accaagacca agcataaaaa tagtgatttc tttaaggaat tagataagga
      841 tcgccgggaa aagaattgtg aatatgctgt tcttgttacc atgcttgaag cagacaatga
      901 ttattacaat gcaggaattg ttgatgtcag tcatgactat gacaaaatgt atgtggttcg
      961 gcctcagctc tttattcatc tcatcggatt gctgcgtaac gctgctctta atagcttaaa
     1021 atataagcaa gaactggcgc ttgtcaggga gcagcacatt gatattacac attttgagga
     1081 ggacctagag cattttaagc atgcttttgc taaaaactac cagtctgcaa gcaataactt
     1141 taaaaaagcc gttgatgaaa ttgataagtc catcaagcgt atggaggagg tcaagcgctt
     1201 tctaacaact agcgaaaatc agctgcgttt agccaataac aagctagatg atgtctctgt
     1261 caaaaaacta accagaaata atccaaccat gcgcgataag tttcaagcaa tcaagcccta
     1321 ggattatctc agtcaggctt attgatagag gctttgttgc ttgtcaaaag ccttgtgaaa
     1381 tggttataat agataggcta atgatcaaaa caataaacga aagtaacaca tgataaacgg
     1441 aataatcaat ttaaaaaaag aagcaggcat gacatcacat gacgctgttt ttaagcttag
     1501 aaagctatta caagaaaaaa agattgggca tggagggacg cttgatcctg acgtggtcgg
     1561 tgttttgcct atagcagtgg ggaaggcaac gcgagttatt gaatacatga cagaagcagg
     1621 taaaacctat gagggagagg ttactcttgg ctattcaacg acaacagagg atgctagtgg
     1681 agagattgtt gaccaaacag tagtgccctt gagtttgact gaagcgatgg ttgatgaggc
     1741 aatgacacaa tttattggtc aaatgactca gattccaccg atgtattctg cggttaaggt
     1801 taatgggcgc aagctttatg attatgcacg agctggtgaa gcagtcgagc gccctaaaag
     1861 acaggtaacg attgaccagt ttgagcggac aagtcccttg acctttgcag gtggtctttg
     1921 ccgatttagc tttagggtga gctgtagcaa ggggacttat attaggacct tggcggttga
     1981 tctaggaaga atgcttggct atgcaagtca tatgtcttgg ctggttcgga cagcttcttc
     2041 gggtttaagt ttggatcagt cctatacctt gtcagagatt gctgagctgc tggataaaaa
     2101 ggacatgagc tttttattgc ctattgaata tggtgttagt gatttagcca gagtagtcgt
     2161 taatgactgg gagctgagag agctttcctt tggtagaaaa atcgctctat catgtgagga
     2221 aaatctgtta gcggcttttt atcaggacag cttgatcgct attttagaaa agcaagaagg
     2281 gctttacaag ccaagaaagg tttttattta gagaagattg atatatggat atacaacaca
     2341 ttaaaagcta tcaggagatt gatgaatcag ctgataccgt tttagtctta ggctactttg
     2401 atggtctgca ccgaggtcac aaggctctat ttgataaggc aaaggaaata tcacgtcagg
     2461 aaagcctaaa aatagtcacc ttgaccttcc atgagtcccc tcagctggcc tttacacgct
     2521 tttctcctga ttttttacga cacattacct atccagaaaa aaggtatgaa aaatttgctg
     2581 agtatggtgt tgataagctt tatttgcttg attttaccac gtcattttca aaactatcct
     2641 ctgatgattt cattgaccac tatattgggc gtttaagggt aaggcatatc gttgtaggct
     2701 ttgattatca ctttgggtgt gatcacgcag atagtcatta cttagctaaa cggataaaag
     2761 gaaccgttta tagcatttca gaggtcaaag aagaccagat caaaatctca tcaacacgta
     2821 tcagaagtct gattacagca ggagatgtcg ctaaggctaa tcagctgctt ggctatgagc
     2881 tttcaacaag aggaatggtt gtgcatggtg atgcgcgtgg gcgaaccatt ggttttccga
     2941 ctgccaatct tgcacctatt gataggacct atctgccagc tgatggtgtt tacgtgacag
     3001 atgtgctggt tagaggaaag cgctatcggt ctatgacgag tatcggcaag aacattacct
     3061 ttggtggtaa agagctgcga ttagaggcaa atatttttga ttttaatgag gacatttatg
     3121 gagaaactct tgaaattatt tggctagata ggattcgtga gatgaataaa tttagtgatg
     3181 ttagcacctt tatcagccaa ctaaagcagg ataaagaagc tgccataaat tggaaaaaag
     3241 atagccaagg ctattaaatt tttgtataat aaggtaagca caattaacag aggaaaagta
     3301 tgattacctt atttctatca ccaagctgta ctagctgccg taaggccaga gcctggctca
     3361 ccaagcatga cgttgacttt caagagcata atattattac cagcccactt agtcgtgagg
     3421 agctgttagc gatcctatcc tttactgaaa atggaacaga ggatattatt tcaacacgat
     3481 caaaggtttt tcaaaaattg gatattgata ttgatgagct gtctatcatg gatttgattg
     3541 atttgatcgc aaagaaccct agccttcttc gtaggccaat cattatggat agtaagcgca
     3601 tgcaaattgg ctttaatgaa gatgagatta gggcattttt gccaagggat tatcgtaagc
     3661 aagagctgcg ccaagcaacc ataaaggcag aaatcgaggg ataacatgtc agatcattat
     3721 cattacccac ttgatgtaag ctggagcact gaagagataa catcagtgct tcatttttta
     3781 aatcaggtag agttagccta tgaggctaag gtaggagcag aggagctact caaaagctat
     3841 gctgcctaca aggagattgt aagaagcaaa tcacaggaaa agcagattga ccgcgaattc
     3901 caacaagcca gtggctattc aacctatcaa gctgtcaaaa aagccagaga aattgagaaa
     3961 ggattctttt cccttggaag ataaatacgc atttgctaaa acgatcatca aagaggctgg
     4021 ccttctgatt aaggatagaa tgaaagatag cttagccatt gaaatcaaga cgcagcatga
     4081 tgatttagtg accaatgtag atcaagagac gcaggatttc ttaattgcta aaatcaaaca
     4141 ggcctatcct agtgaccata tgattgctga ggagggcggt atctgtcatg ctattacaga
     4201 tggcaaggtt tgggtgctgg atcctattga tggtacggtg aattttattg tacagaaagc
     4261 caattttgcg atcatgatgg cttattatga gaatggcgtc ggaaaattta gtctcattta
     4321 tgatgtcatg gcagatcagc ttttttcagg tggaggagat tttgctgtta ctttaaatga
     4381 tcaagtccta gcatcttatc aggataagcc gcttgatcgt agcttaattg gctgcaatgc
     4441 aggtatgctt tcaaggaacg attacaacct gcaccagttg attgatcaaa ccctaggagt
     4501 gagggtttat ggcggtgcag gcatttgcat gactaaggtg ttaaggcagc agctaatggc
     4561 ttatttctct tatattcaac cttgggatta tgcagcggca gccattatgg gcgaaagcct
     4621 tggctatgtc ctgttgacct tggagggaaa gcagccagac tttcagtcta gacagaaggt
     4681 gatgtttgtt cccaagtcta aactagccac cattcaatct ctgctgaaaa caaacgagaa
     4741 tacccaataa gattaaaatg aaaagcatgc aattaccaaa cgattttatt gaaaaatacc
     4801 aacagctgct aggttcagaa gcaaaagctt tttttgagag ctttgatcag cctgccatca
     4861 gtgcctacag gataaatccc ttaaagcacc aatcggtctg ccttgatcct cctattcctg
     4921 atacaccatg gggttactac ggcagggtat caggaaagtc tcctaaccac gtgtcaggtg
     4981 tggtgtattc ccaagagcct gctgctcaaa tggttgctca ggtggcctca cctgccaagg
     5041 gaactagagt gttggatttg gcagcagcgc caggtggcaa gtcaactcag ttacttgcct
     5101 atctagagaa tacaggactt ttagtgagta atgagatttc gaccaaacgc agcaaggcct
     5161 tagttgaaaa tatagagcgc tttggtgcta gaaatgttat tgtgacaaat gagtcagctg
     5221 acagactggc tgctgttttt ccagaatatt ttgacactat tgtctttgac gggccttgct
     5281 ctggtgaggg catgtttcgc aaggatccaa atgctgttag ctattggcac aaggattacc
     5341 cagcagcatg tgctagcctg caaagatcca ttttagcaga ggcgatacct atgctaaagc
     5401 caggtggtca gctgatttat tcgacctgca cctggtcgcc tgaagaaaat gaagaggttg
     5461 ttcgctggct actagaaagt tatgattttc ttgagctgga gcatatccct aagatcaatg
     5521 gtatggcaga ggggatcggt atgccacagg cagctagaat gtaccctcat cgctttaaag
     5581 gagagggaca gtttgttgct aagttaaagg atactagatc aacgatttcc tcttcaagct
     5641 acaaatctcc aaggtctaac ctcactcaag agcagctgag gctgtggcag gattttgaaa
     5701 aaaatcattt gaacataacc ttgtctggcc tattacaggt ctttggtgat cgtttgtact
     5761 tgttaccaga tggcttaccc tgtcttcgat cgcttaaaat agcaagaaat ggtctggaat
     5821 taggcacttt taagaaaaaa cgctttgagc cttcctatgc tctgggcttg gcattaagac
     5881 ctgaagaggt cagcttatct gttgagatta acgaagagga ctttgtcaca tacgcctcag
     5941 gaaataccat taccttacca gaatcttatg ctacagattg gtatcagctg gtcattaacg
     6001 gaaatggtct gggctttgct aaaatagttg gtcgcaccct taaaaatagc ttccctaagg
     6061 gcttacgttt ttaaggaatg gcataccatt aaatttttat aaatttaaat aaaacttctt
     6121 ccaaagcatt gttagatatg ttaatataaa gaatatgctg aagcttaatt cttcgctata
     6181 aacctttatt tttatgaata ggaatagaat aatgaaatcg aaaaagaaat tctttttgtt
     6241 aagtctttta gccttgtcgg ctttcttttt gtcagcctgc tcaagctgga ttgataaggg
     6301 agaatccata acagcggtag gctcaacagc attacagccc ttagtagaag ccgcagctga
     6361 tgagtttgga agcaataacc tcggaaaatc tgttaatgtt caaggaggcg gctctggcac
     6421 tggcttatca caggtgcagt caggtgctgt tcaggtaggc aatagtgatg tctttgcaga
     6481 agaaaaggac gggattgatg ctgctaagct tgttgatcac caggttgccg tagcaggact
     6541 tgctgtcatt gccaatccta aggtcaaggt atctaatctc acaagcaagc agctacaaaa
     6601 gattttctca ggtgaatata ccaactggaa gcaggttggt ggacaggatc ttgctatttc
     6661 agtgattaat cgagcggcaa gctcaggctc acgtgctacc tttgatagtg tcatcatgaa
     6721 gggtgttact gctaagcaaa gtcaagagca ggattctaac ggtatggtta aatcaattgt
     6781 gtctcagaca ccgggggcca tttcttactt atcctttgcc tatgtggatt cgtctgtaaa
     6841 atcattacga ttgaatggct ttaaggccaa tgccaaaaat gtagcaacca atgattggcc
     6901 catctggtcc tatgagcata tgtataccaa aggcaagcca gacggcttaa ccaaggaatt
     6961 tttggattat gtgctatcag atgaggtcca aaaaaccatt gtgacacata tgggttatat
     7021 tgctatcact gatatgaagg tcgtcaaatc ctatgatgga aaagttacag ataaataatg
     7081 ggggaattat gaaaaatcag gaattagcta agcaattagc ctcaccatca aaaaattcac
     7141 gacttgaagc atttggtcgt acgattacct ttttttgcct cgccttaatt gtttttatcg
     7201 ttgcaatgat tttacttttt gtggctcaaa agggcttgtc tacctttttt gtaaacaagg
     7261 ttaatctttt tgatttccta tttggtacag agtggcagcc tagcgttaaa aatgctgccg
     7321 gtgttcctta tcttggagct cttccgatga ttgctggatc gtttttagtc acgattttat
     7381 cagccttggt ggcaacacca tttgccattg gggcagcagt atttatgact gaaatttcac
     7441 ccaagtacgg ggcaaaacta ttacagccag cagttgaatt gcttgtaggt atcccgtcag
     7501 ttgtttatgg ctttattggc ttgcaggttg ttgttccttt tattcgttct atttttggtg
     7561 gaacaggctt tggtatccta tcaggggtct gtgtcttgtt tgtcatgatt ttaccgacgg
     7621 ttacctttat gacaacagat agtctgcgcg ctgttcctcg tcattatcgt gaggcttcta
     7681 tggctatggg ggctacacgt tggcaaacca tttggcgagt ggttttaaat gcggctcgtc
     7741 ctggtatttt tactgctgtt atttttggta tggctagagc ctttggtgag gccttagcca
     7801 ttcaaatggt tgtgggaaat tcagcagtca tgccggcttc actaaccact ccagcggcta
     7861 cattgacctc tgtattgact atgggaattg gtaatacagt tatgggaact gttcaaaata
     7921 atgtgctatg gtcattagcc cttgtcttat tgctgatgag tctagctttt aattcccttg
     7981 tcaaattaat tacgaaagag agaaagagaa attatgaacg ctaaaaaggt tgataaagta
     8041 gcaactggta gcttgtatac tattgctgga attattgtag ctattttagc ttccctaatt
     8101 ctgtttattc ttgtgcgtgg cctacctcac atcagctggt cgtttttaac agggaaatca
     8161 tcgtcctatg aagctggtgg aggtattggg attcagcttt ataattcatt tttcttgctg
     8221 gtagtaacct tgattatttc cattccccta tcaacaggtg ctggcattta tttggccgaa
     8281 tacgctaaaa aaggacctgt gacaaatgtg attagaacct gtattgaaat cctatcctca
     8341 ttgccatctg ttgtggttgg attgtttggc taccttattt ttgttgtaca gtttgaatat
     8401 ggcttttcta ttatatcagg tgcccttgct ttgacggtat ttaatcttcc gcaaatgaca
     8461 agaaacgttg aggatagctt gctgcatgtg catcatactc aaagagaggc agggctagcc
     8521 cttgggcttt cacgctggga aacggttttt catgtggtta ttccagaggc cttgccaagt
     8581 attgtgacag gtattgtttt ggcttcaggt cgtatctttg gtgaagcagc tgctcttatc
     8641 tatactgcgg gtcagtctgc cccagcgctt gattggtcaa attggaaccc tttgagcgtg
     8701 acaagcccta tttcaatttt ccgtcaatct gaaaccctag ctgttcatat ttggaaggtc
     8761 aatagtgaag ggacaatccc tgatgcaaca cttgtttctg ctggtagtgc agcggtgttg
     8821 ttgattttta tccttatttt caatctatca gctcgcttta ttggcaagcg tattcatgct
     8881 aagatgacag cagcaaaata agacattgga gagattcatg acagaatata attggaacga
     8941 acgtcatatc attacatttc cagaagaaac gattgcccta gctactaagg atctgcatgt
     9001 ttattatggt agcaaggagg caatcaaggg gattgatatg caattcgaaa aaaataaaat
     9061 tacagcccta attggaccct caggctgtgg caagtcaacc tatctgcgca gcctcaatcg
     9121 catgaatgac accattgata ttgctagagt aacaggtgaa attttgtatc aaggcattga
     9181 tgtcaatcga aaggacatga atgtgtatga aatccgtaag cacctaggaa tggtctttca
     9241 aaggccaaat ccatttgcca agtctattta taaaaacatc acctttgctc atgaaagagc
     9301 aggagtgaga gataaaaggg ttttagatga gattgtcgaa acctccctca agcaggctgc
     9361 actatgggat caggtcaagg acgatcttca taaatcagcc tttacccttt caggaggtca
     9421 gcagcagcgc ttgtgtattg ctagggctat ttcggttaag ccggatatct tgttgatgga
     9481 cgaaccagct tcagcccttg atcctattgc aaccatgcag ctagaagaaa ccatgtttga
     9541 gttgaagaag gattacacca ttattatcgt tactcataac atgcagcagg ccgctagagc
     9601 aagtgattac actgctttct tctatttggg tgacttaatt gaatacgata aaacgcgtaa
     9661 cattttccaa aacgctacct gtcagtccac aaatgattac gtctcagggc actttggtta
     9721 gaaagaagga tatgatggca gaacctattt tacaaatcag agatctttct gtttactata
     9781 ataaaaagaa aaccttaaag gacgtgtcct tagattttta cccaaatgaa atcacagcac
     9841 tcattggccc ttcagggtct gggaaatcaa cacttttgcg ttccatcaat cgcatgaatg
     9901 acctgaatcc agaggtaacc attacggggt caatcgttta taatggacat aacatttaca
     9961 gtccaagaac agacactgtt gatttgcgaa aagaaattgg tatggtcttt cagcagccca
    10021 atccctttcc aatgtctatc tatgaaaacg ttgtctatgg cttgcgccta aagggcatta
    10081 gagataaggc tgttttagat cacgctgttg aatcctctct caaaggagcc tccatctgga
    10141 gtgaggtcaa ggataggctt catgattcag ctgttggact atcaggaggt caacagcagc
    10201 gtgtctgcat agcaagggtt ctggcaacca gccctaaaat cattttgtta gatgagccaa
    10261 catcggcttt agatcccatt tcagccggca aaatcgaaga gaccctgttc tcactaaaaa
    10321 aggattatac gatggttatc gttacccgct ccatgcagca ggcctcgcgc ttgtcagacc
    10381 ggacaggctt cttcttagag ggagaccttc ttgagtttgg tcctactaag gcaatgttta
    10441 tgaaccctaa gaggaaggaa acagaagatt atatttcggg taaatttggc taagggatct
    10501 tgtttgtagt ctaggtatcc gctctgttta ggataataaa tgaatcaata gaaagaaaaa
    10561 atgatgttaa gaactaaatt tgaagaagaa ttagacaagc tacacaatca gttttactct
    10621 atgggaacag aagtcttgtc tcaaatcaat aaaaccgttc gtgcctttgt cagtcatgac
    10681 cgcgaattgg ccaaagaggt gattgaggaa gacgatacca tcaatggatt tgaaacaaaa
    10741 ttagaaaaaa agtctcttga aattatcgcc ttacagcagc ctgtttcaaa cgatttgcga
    10801 acagttatta ctgttttgaa ggcctcaagt gatattgagc gtatgggaga tcacgctgcc
    10861 tctatcgcta aagcaaccat tcgcatgaaa ggagaagagc gtatcccgat tgttgaggag
    10921 catatcaact tgatggggaa ggcagtcaag cagatggttg aagaggcgct aaatgcttat
    10981 attaatgcag atgatgccaa ggcctatgaa attgctgctt cagacgaaat cattgataat
    11041 tatttccgcg aaatccaatc tctagctgtc gaagaaattc gcaagacacc agatgccgtc
    11101 tttgctggca aggaatactt ccaggttctc atgtatttag agcgtatcgg tgactatgct
    11161 cgtaatattt gtgaatggat tgtctattta aaaactggaa aaattattga attataagaa
    11221 agtatggtat aatgggggct gggtgaactt ctcagttcct cgttttatta tagcgattaa
    11281 aaggttttag aggctggagc ttcagctgag ctgactatca gctgtcaagc ttctagacaa
    11341 aatgaaagat aacaataagc tagtcgtcta agggactaga cggcaggatt gattatatta
    11401 agaatgtgac cttgtcccat cactaattta atgacatatt aaggagttgt atgaaaaaag
    11461 tagaacatct tattgaaaag tttattcctg aaaattataa tattttctta gacattaatc
    11521 gcagcacaaa aaccttcaca ggtaatgttg caatcaatgg tgaagcatta gataatcaag
    11581 tgtcatttca ccaaaaggac ttggcaatca atgccatttt acttgacaat gaagctgtta
    11641 gctatcatgt tgacgatgac aatgagcttg tgcgtgttga gctgccagag actggtatga
    11701 tgacgcttgt cattgaattt tcaggtaata ttactgacaa tatgactggt atttacccgt
    11761 cctattacac aaaagatggt gaaaaacagg aggttatttc aacgcagttt gaaagccatt
    11821 ttgcgcgtga ggcctttcca tgtattgacg agcctgaagc aaaggctacc tttgacttaa
    11881 gcttgacatt tgaccaagca gagggcgaga ttgctctatc aaatatgcct gaggtcaatg
    11941 ctgagcgccg caaggagacc ggtctttgga cctttgagac aactcctaga atgtcttctt
    12001 atctgctggc ctttgcctta ggagacttgc atggcaaaac aacaaaaagt aaaaacggga
    12061 caacagttgg tgtttatgca accaaggctc acccactgac ctcgctagat ttttcattgg
    12121 atattgctgt acgtgtcatt gatttttacg aagactactt tggggttcgc tatcctattc
    12181 cgcaatctct aaatattgct cttcctgatt tttcatctgg agcgatggaa aactggggct
    12241 tgattaccta tcgtgaaatt tacctgttgg ttgatggcaa ttcaacagcc cgcagcagac
    12301 aaaatgttgc tcttgttgtg gcacacgaga ttgcccatca atggtttggt aatcttgtaa
    12361 ccatgaaatg gtgggacgat ctttggctaa atgaaagctt tgccaatatg atggaatatg
    12421 tagccatcaa tgctattgag ccgtcatggc gtatttttga ggatttccaa acaacaggtg
    12481 tgccgctggc tcttaagcgt gatgcaacag acggtgttca atcagtccat gttgctgtta
    12541 atcacccaga tgagattaat accctgtttg atccagctat tgtctatgcc aaaggtagcc
    12601 gcttaatgca tatgcttcgt cgctggattg gcgataagga ttttgcggca ggtctgcgcc
    12661 tttactttga aaagcatcaa taccgtaata ctgtaggacg tgatttgtgg caggctcttt
    12721 cagaagcttc tggtaaagat gttgctgcgt ttatggacgc ttggctagag cagccaggct
    12781 atcctgtctt aacggccaga gttgacaatg atcagttgat tctcagccaa aagcagttct
    12841 ttattggtga ggcaagcgac caaaagagac tatggccaat tccactaaat gcgaactgga
    12901 aaggtcttcc tgacgtactg acagaggagt ccatcgttat ttcaggcttt agtcaattag
    12961 ccgcccaaaa taaaggaaca cttcgcttta atacagaaaa tacagcgcat tacattacag
    13021 attatcaggg acagctcttt catagcttag ttgatgattt gaagcatctt gacaacacct
    13081 ctgcccttca agtgattcaa gagcgccgct tgctggctga tagcggtctg atttcttatg
    13141 cagagctggt tgacttaatc gctcagctag atgacaaaaa atcctatatg gttgctgcag
    13201 ctgttcagca ggttattaga ggcttagagc agttcattga tgaaggaacc tcagcagagc
    13261 agtccttcaa tcgattgatt tcttctattt tccaagagga cttcaggcag cttggatttg
    13321 aaaagagggc aaatgaatct gatgaagatg aaatggttcg tcaaattgct ttacatcacc
    13381 tgttggttgg aggcaatcgt gatgtgatca agcaggccaa gactatcttt gaagcttatg
    13441 caaatcgtat cgaagccatt ccagcagcca ttcgccgctc ggtattggtg agtcagatca
    13501 agtattttga aatagctgac ttggttgatg cttattttga tgcttatgtt gcaaccaagg
    13561 acaacaatct tcgagctgat ttgagcgccg ccttagcaac aacagctaat ccatcaactc
    13621 ttaagcgcat tcagtacagc ttaaaggata aggatattat taagccacag gacttagcag
    13681 cttggtacag ctttttgctt gatcaggcct ctgcacaaga aagcatttgg cgttgggcta
    13741 gagaaaattg gaagtggatt aaggcttcac tgggtggtga tatgagcttt gacaagttta
    13801 ttatttaccc tgctaaccat tttaaaacag cagagcgttt agctgaatat aaggccttct
    13861 ttgagccaca gcttgatgat atggcgatta gtcgcaatat ttcgatgggg ataaatgaaa
    13921 tttcagctcg agttgccctc attgatagtg aaaaggaagc tatcgctaat gctttaagtc
    13981 agtactaatg atatcacaaa ggagctgggg accatcctca actcctttat tggtgtcaaa
    14041 gctactatct ttaagtaaca tttagatcaa agggtaattg ctgtagctta gtggcactgc
    14101 ctgtcagctt ttggcaaatg aggaggcttc aatcataagc agtggttaat cttagcgccg
    14161 taaattacta gttgatcaga gtcagagctt aggacggata ggtcatagag acaattcttt
    14221 gtctgtcagt tttataactt aagtaggtct ccagactaac tgtatgctta tgacctgtca
    14281 tgagcaatag tttagcaaag cttaagcttt ttgtgttatc gttagattag agaattcatt
    14341 tagtaaggta atccctaaag actacttgag cgaggctgtt agtctttaga gaattgaggt
    14401 atcataatga taaaactatt attagtagaa gacgatttaa gcttgtcaaa ttctatcttt
    14461 gattttttag atgactttgc tgatgtgacg caggtttttg atggtgacga aggactctat
    14521 gaggcagaaa gcggtattta tgatttgatt ctgttagatt tgatgctgcc tgaaaaggat
    14581 ggctttcaag tgttaaaagc cttacgtgaa aaagacatca aaattcccgt cttgatcatg
    14641 actgccaaag aaagcatcga tgacaaaggg catggctttg agcttggtgc tgatgactat
    14701 ttaaccaagc ccttttacct agaagaatta aaaatgcgga ttcaggcctt gcttaagcgc
    14761 gtaggaaagt ttaatgacaa gagccttaaa tttggcaacc tgactgtaga tactacccgt
    14821 aaagaggtac aggtcaatgg gcaggccata gagctattag gcaaggagct tgatttacta
    14881 atctatatcc ttcaaaatca aaatgttatt ttgccaaaat cacaaatttt tgatcgtatc
    14941 tggggctttg atagtgatac cactatctct gttgtagagg tctatgtctc taaaattcgt
    15001 aagaagctta aggggacaga ctttgttaat catcttcaaa ccttgagaag tgtaggatat
    15061 atcttaaaag ctaatgaata aactaaaaaa aggattattg tccgataatt atacgcattt
    15121 ttttcatttc tttgctattt ttacaggcat ttttgttgtc atgaccatca ttattttaca
    15181 aatcatgagg tttagtgtct attccacagt agacagcagt ctcatttcgg tcagtcaaaa
    15241 tgccagcaac tatgctaata ggaccatggc gagaatatct tccttttatt ttgatgcaga
    15301 aaataacctt attcaggctc ttcctgaact ggaagcgtca aaatcacttg gctcctccac
    15361 cactaatatg gatattattt tatttagtgc taatgggacg atattgaact cctttgacgc
    15421 tttctctaat taccaaagct ttcgtttaga caaaagccag ctcaataaca ttgtcaccac
    15481 acagctgatg aatttttatg ggcaaaagga gaaataccat accctaaccg ttaaggttca
    15541 cattaaaaac tatccagcag tggcttatat gatggcagtg gttaatgttc agcagctgga
    15601 tactgctaat gagcgctatg aacagattat tatcatggtt atgattgtct tttggttaat
    15661 ttcgattttg gccagtattt atttggctaa gtggagcaga aagccaatta tggagagcta
    15721 tgccaagcaa aaaatgtttg tagaaaatgc cagtcatgag cttaggactc ctttagcggt
    15781 gctgcaaaat cgtttggaat cgctgtttag aaagcctaac gaaaccattt tagacaatag
    15841 cgagcatatt gcgtcaagcc tagatgaggt tcgtaatatg agaatattaa caactaatct
    15901 gttaaattta gccagaagtg atgatgggat caagccgcag ctagttgatg ttgatgcagc
    15961 cttttttgat actgtttttg aaaattatca attagttgca gaagagtcag gcaagcagtt
    16021 tatctcagtt aatcagatca ataggccctt aaagacggat aaggctttgc tcaagcagct
    16081 gatgaccatt ttgtttgata atgcgatcaa atacactgat cataacggtg tggttgaggt
    16141 caaggttaga acgaccgata agcatttatt gatttctgtt attgataatg gcccagggat
    16201 caaggatgat gataagaaaa agatttttga tcgcttttac cgagtggata aggcaagggc
    16261 acgccaaaaa ggagggtttg gactcggatt ggccttagcg cagcagatcg ttacctcatt
    16321 aaaaggaacg attaccgtca gtgataataa gcctaccggc gccatctttg aagtaaaatt
    16381 atagcactga gttcttgcta gcccataatc agtatgaaaa taacagtcac tagatcaaga
    16441 agtctagtga ctttttttat tgtcttcttt ttgctgttga ccaagcagtt gacaagaaaa
    16501 ttccaataga tagtttaaag ccaataaaac cattattagg cttgcattac aggcaggtat
    16561 caaacaaaga tatagaaaaa tataccataa aaaatctcat aaaagtgtca aaatggtaaa
    16621 aaattgccaa caatatgtcg atattatacc attattatag tataatattt ataatcgtat
    16681 cataatatta aaatatctgg tgtctagctg tttttgtaaa agcaaaaaac ttgcaacacc
    16741 ttatgataaa gcataaagga atacaagcat gatagtctac ctaaagcaac acaaaaatta
    16801 ctggaaatta gtcagcatag ccgctttaat cattatttta ggaggaatac taacaatgaa
    16861 ttggcttaat ggcgaagagc taaaaaagaa aaagtacaga caagagcagg atagggtagt
    16921 gaaatacata ggagagcata tagagctatg taatggtcag cctataacaa aaattgagtt
    16981 tatagaattt cagttagaaa ctgcaaccac cggaacttgg tcaataacaa caattgttaa
    17041 tgagaaatat ctgattcatt tttcagaaga tagattaggt gaagaaatac ggacttccta
    17101 ttattctcca aaagaattta agcaatacag tgaaaagatg aggaataata tgactaatgt
    17161 tgaaacaatt tattacgagg agaaatgatg attgatagag attataaaaa tatttcagag
    17221 gatgtgtata aggttgattc tggtaaagaa agagatccga ttcaagaagg atatccggtt
    17281 gccaatggaa aataccgcgt tcttgaagcc gaagataacc ccgacaatgg tatgcaggct
    17341 atggctgttg tgccaataaa agatggcaaa gaggatagaa gtcatatcgt cattgcctat
    17401 gccgggacaa atagcagtga tatacgcgat attgacaccg atattcaatc cgttgttttt
    17461 ggagatgatc aatacctgtg tacccatgag gagcctgatt cttttaaagt ggtcaagagt
    17521 cagctaagta ctgctaaagc cttttccgac tacattagga caagctaccc taacgctgcc
    17581 atctcctaca ccggacactc tctgggaggc tatctggcac tcatcacagc tgcccatgcc
    17641 aagcagcctg ccactgtctt taatgcgcca agctctgtta ataacctctc caaggaggct
    17701 attgactttg ttaaagccaa caagggactc taccacagct accgcattaa caatgactac
    17761 attggaaatc tgggcactta ctttggagat gatgagctag ggatttcaag atgggttgac
    17821 ggtaaggcgg gaataggacg tcatagctta gccgcttatc gcttcaactc aaagggtcag
    17881 gtgattgacc gtaagggtcg tcctgccgct gctcaagcac ctgctcttgc taccctaagc
    17941 tcaaagctaa ccgaataccg cctgctaaag aaaaagtatg tagcctctaa cggtattagc
    18001 agctcagagg agttttacct tgatcagttt caggctcgag cagtcgcaca ggctttggag
    18061 cagaccactc agcttgccca agaggagatc attgctcgcc ggaaggaggc ggttgcagag
    18121 gcagaggc
//
LOCUS       DARYXW010000039        18070 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.039, whole genome shotgun sequence.
ACCESSION   DARYXW010000039 DARYXW010000000
VERSION     DARYXW010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18070
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.039"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            182..409
                     /locus_tag="TV191_001078"
     CDS             182..409
                     /locus_tag="TV191_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507601.1"
                     /translation="MTKNDFLTGFVLILLAACIFAAGFVIGSDCSSEHYEQQMTGLRM
                     QLVNTQQQLKRASEDRARRTKRIADLTGNGG"
     gene            413..835
                     /locus_tag="TV191_001079"
     CDS             413..835
                     /locus_tag="TV191_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEL1507602.1"
                     /translation="MIDEIELDLQKPEIPQFVADYIDDMHKNARTLRYAFKYMESNIK
                     MHKWCVFERQETFVNAFLYGYTIKKEKLYIVEIPNPNSGIEHKHIALARLANGKLGFS
                     EIIDTDFYSREDVRLTESEIRKDFDWAWREGFAKEVTE"
     gene            1003..1233
                     /locus_tag="TV191_001080"
     CDS             1003..1233
                     /locus_tag="TV191_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003077369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507603.1"
                     /translation="MAYLREERETVIHYDELDDCWTFETNVRRHITKIEKRIELYEIL
                     SEEFDDRGRRIYICAKMKTGTVSPFAKPPRRK"
     gene            1610..2044
                     /locus_tag="TV191_001081"
     CDS             1610..2044
                     /locus_tag="TV191_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HEL1507604.1"
                     /translation="MTFFPEIDIQKTKSNAKRKLKEYPRWRRIANDVDTQKVTATYSF
                     EPRQPHGVHSKPVERLALNRVSAEQELDAIEQAVSMILEPERRRILYDKYLSPYKKAD
                     KVIYTELCMSESFYYDTLDIALLAFAELYREGSLIVEQGVFS"
     gene            2582..2656
                     /locus_tag="TV191_001082"
     tRNA            2582..2656
                     /locus_tag="TV191_001082"
                     /product="tRNA-OTHER"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
     gene            2815..3306
                     /locus_tag="TV191_001083"
     CDS             2815..3306
                     /locus_tag="TV191_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011834794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEL1507605.1"
                     /translation="MAKLTIKQQKFIDEYIICGNATEAALKAGYSKKTAGQIGEQNLK
                     KLEIKSAINERLKQLESSKIASAIEILQVLTAVLRQDLTEEVVTLNPVTGEYVTMQKK
                     PSIAEVIKAAGELLKRYPIQEQIEKIKQENELLRLKIETVKGAKPDTHLMEKLLEVIE
                     DGG"
     gene            3341..4594
                     /locus_tag="TV191_001084"
     CDS             3341..4594
                     /locus_tag="TV191_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEL1507606.1"
                     /translation="MRRPFNYELEVNEGTPRSGKTTAGHFRYARYLIESEDENHLVTA
                     YNQEQAYRLFIDGDGTGLMHIFDGNCEIKHDERGDHLLVTTPKGNKRVYYKGGGKVNS
                     VGAITGMSLGSVVFCEINLLHMDFIQECFRRTWAAKLRYHLADLNPPAPQHPVIKDVF
                     DVQNTRWTHWTMDDNPILTAERKQNIINSLKKNPYLYKRDVLGQRVMPQGVIYGLFDM
                     EKNVLDTLIGEPVEMYFCADGGQSDATSMSCNIVTRVRDNGKISFRLNRTAHYYHSGA
                     DTGQVKAMSTYARELKAFIDWCVKKYQLRYSDVFIDPACKALREELHAIGILTTGAPN
                     NAHDVNSKAKGIEVGIERGQTLISDGDFYLVNHKEEKYDHYHFLKELGLYSRDDKGKP
                     IDANNHSMDEFRYSVNVFVGRYKMK"
     gene            4604..6103
                     /locus_tag="TV191_001085"
     CDS             4604..6103
                     /locus_tag="TV191_001085"
                     /inference="COORDINATES: protein motif:HMM:TIGR01542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL1507607.1"
                     /translation="MFRNLWTKIKGVMQKMGLIKGLKDLNLHREIELSDKHYDSIQIW
                     KELYQGYHDKIHDYYEKSILDGRKKKKRLTLNMPKVVTSELATLIFNEKCEINIGSEN
                     ESLTKLITETLEKNNFTQEFQRFLEYSFALGGMAIKAYLKKDGTIGLNFVQADSFIPI
                     SWDNAGISEAVFVDTQHRGKYKYTHLEWHTWESELYVVAHELFRTDKSNDDVGIRVPI
                     TEIYPDLKSQVVIEKLSRPLFVYLKPNSANNIDLSSPLGISIYHNSFDTLRAIDIAYD
                     SFEREFRLGRKRILVPATAIRTVVDSEGNFHRYFDATDETYEAFHTGEDSKIQDIKDI
                     SVELRVDEHIAAINALLNLLSMQIGFSPGSFSFDGVSGVKTATEVISENSKTFRTKQS
                     HETMVEATLKNLVAIIVDFGDLYGLIEGESKYNVTVTFDDSIAQDRTQDAQYYIGLVA
                     AGLISKKKAMMKLFNLSEEDAELEIQTIHEESRTTNDMSIDLFGLDGDA"
     gene            6103..7713
                     /locus_tag="TV191_001086"
     CDS             6103..7713
                     /locus_tag="TV191_001086"
                     /inference="COORDINATES: protein motif:HMM:NF017919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507608.1"
                     /translation="MDYDTHIQLSFDLIELYSDVERELLTSIGRRFAKHYDEMVAGDI
                     MDWQIRQLLEVGELRKEHIEIMRKSARVSRERMIEMLTEAGYTSAGRYEDFFKEAYVK
                     GLIKLNPSAADNSMRLLRVLNTYINQAEDTLNLVNTTMLQSGQDTFLDTVNQVVAYVS
                     TGIKTPQVAMRDALKNAGQKGLTVFRAKNGAQWSTETYLNMITRTMNSNISNAMEDER
                     RHEYGVDYIEVSSHAGARPRCAPYQGRIYYDGVGDDPLEKYPHFSETSYGEAAGLFGV
                     NCGHHKYPYVPGMSKQTFFPYSKSENDKTYAESQVQRKLEREVKQLKRERAILTAAKD
                     KEGAKLASQRLENKWQELRQFTAQTGRTRRYDREKSLNTILSEDKKKAIVKDNLKIRD
                     EYRAIKKAIPEVAPKNLETYYDMRYNGGKIYEDLVRDYKDYIRWSKAEFPTKKSFEGH
                     IDSHLKEFPGLTGKQYQKKAADLLSRPITDNILGYDTDSRRVRYDLENNIFALGRVKQ
                     GTITTMLKPKEGVDYFDNDWKREFDNLK"
     gene            7679..7900
                     /locus_tag="TV191_001087"
     CDS             7679..7900
                     /locus_tag="TV191_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507609.1"
                     /translation="MTGKESLIILNDLEYVHCPVCGTLTEVYDICDTCKWQNTGETNI
                     DGGPNYITLEEARRRWANGEPLRNFFKDQ"
     gene            7952..8236
                     /locus_tag="TV191_001088"
     CDS             7952..8236
                     /locus_tag="TV191_001088"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507610.1"
                     /translation="MNKRIEKKRRTQMMLDRILRIVELMSQATDDNFAILEKRLEKAE
                     KRNEELMEIILVNVKEVNNRFDELEICQKIVEDDVAELKKAKKKGWFSRK"
     gene            8322..8561
                     /locus_tag="TV191_001089"
     CDS             8322..8561
                     /locus_tag="TV191_001089"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507611.1"
                     /translation="MAVIIVQTRGGDIEVPTPLPAMQANKAIQSQLFDKELTFLCVDN
                     HAFAKTEVLHVLVETEEDEELPQSKHKEEETCYMD"
     gene            8546..9148
                     /locus_tag="TV191_001090"
     CDS             8546..9148
                     /locus_tag="TV191_001090"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507612.1"
                     /translation="MLHGLKHRLFKLAPDTGAGGGAEVTSETNAEAGRVEQTVSQQQA
                     DPVDTEAIKNQAINEVLSQLGVSSVEDAKANLASWNEYQEGQKTEFQKIQDSLTVANN
                     SLAERDTMIASLQAQLAAAQMGVPAENTSDVITLANSLVHDKTDINAAITTVLEKYPH
                     FKGGDADVADKPNFVTQTQSQTETTEDAFFKALGLTIKED"
     gene            9150..10022
                     /locus_tag="TV191_001091"
     CDS             9150..10022
                     /locus_tag="TV191_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003039217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507613.1"
                     /translation="MSINYITKHEGIFEKKLMQGALTSNLETPKVNWLGAKSFELPTI
                     SVTGYKAHTRSKGYNAGTVSNDKNTYTLGFDRDVEFFVDKADVDETNQELSMANISNT
                     FITEHATPEVDAYRFSKIATNAIDNSHFKQEDDYSTTNVYERLKAAILPIRKYGAGNI
                     IIYVSSEIMDFLERSKDFTRSIATTSPQGIDTRVTSLDGVQLIEVWDDARFKTKFDFT
                     TGFVKDGSGKDINFLIVAKPAVIAKAKFNSIYLFAPGQHTEGDGYLYQNRLYHDLFVL
                     KSKQDGVYVSHKSA"
     gene            10033..10281
                     /locus_tag="TV191_001092"
     CDS             10033..10281
                     /locus_tag="TV191_001092"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507614.1"
                     /translation="MKTYEKDNQVYKVQEGSELEIQLIADGFKEIIEANEKETDITKM
                     KLDKLKAYAENEGIIIPEDIKKKEDVLAFIKEQQQRGE"
     gene            10284..10670
                     /locus_tag="TV191_001093"
     CDS             10284..10670
                     /locus_tag="TV191_001093"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507615.1"
                     /translation="MLTFDFYNKGYCGSQLNEEKFGELSKRAERKILALIGLKKEQVK
                     NLPLDILEAVKMAVCAQIEYLNAIGVESAIGVTSVTQAKVGNFSYTDGKKATVSASVG
                     SVGVSPDVLDYLLPSGLLYKGVNTRW"
     gene            10664..11008
                     /locus_tag="TV191_001094"
     CDS             10664..11008
                     /locus_tag="TV191_001094"
                     /inference="COORDINATES: protein motif:HMM:NF022130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507616.1"
                     /translation="MVKEVKPIPKELLVDTVTYLAVGNKDSWGAETVVSTELSQVLVQ
                     PRSSIQRGQQNESNSYELLLFFDCVNSLPVDHQFKVDDKISYLGKEYRIASVEVLKAF
                     DQSPHHYEVMLE"
     gene            11005..11358
                     /locus_tag="TV191_001095"
     CDS             11005..11358
                     /locus_tag="TV191_001095"
                     /inference="COORDINATES: protein motif:HMM:NF022564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507617.1"
                     /translation="MIGFKVEVIFNASKLIAKSEASAKTARFALSGQIKKDSDKYIPA
                     REWNLRDSGRVTERSVSWHTPYARRLYYNPQYNFSKDKNPNAQGKWFEVAKANHAEHW
                     YELTKKAYGAEFRGD"
     gene            11361..11729
                     /locus_tag="TV191_001096"
     CDS             11361..11729
                     /locus_tag="TV191_001096"
                     /inference="COORDINATES: protein motif:HMM:NF024103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507618.1"
                     /translation="MTFIDFLLRKVQEVSGAEPVLGIMGNSDKVAIIPMAGNFDNRAL
                     DESKIRIFTFQVLAKSKKQQEAFLTTENLVNGLDGLSNEPFTGGYLIKLECTTTTNFV
                     EKDSDKNYLYTALFRAELGG"
     gene            11733..12230
                     /locus_tag="TV191_001097"
     CDS             11733..12230
                     /locus_tag="TV191_001097"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507619.1"
                     /translation="MAADKPTFYLQSEHKLEISEDGKTWMRLAGGISELEPDGNEEVS
                     QDAYLDGSESDVTGGQLVLALTGHRLVGDKAQDWIYARQFRYGGKRRGFTRWTLPGGK
                     TQFTFASTFANIKGPSGAANGKGEIEFEIHSNETLVPNKVVVEVTKTNKELASEALGL
                     ERQER"
     gene            12250..12657
                     /locus_tag="TV191_001098"
     CDS             12250..12657
                     /locus_tag="TV191_001098"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507620.1"
                     /translation="MVRQFEFKKTVEEIEIAGEIYLLPLDDDNLLRIQRDFISYGKEI
                     EELQKVEVEKGDPDDLADNHKQQLLVMKKVIESPFGEGSFEKLYEASGHSLMNMVDLL
                     DYLVELVAEKVEQNKARATKAKEKYYSSKRKKK"
     gene            12665..13282
                     /locus_tag="TV191_001099"
     CDS             12665..13282
                     /locus_tag="TV191_001099"
                     /inference="COORDINATES: protein motif:HMM:NF018553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507621.1"
                     /translation="MKLTETYEVLADAFEFGGHIVTVDLAFDVVLRVMELLADAEVND
                     YAKIVWTLDMLLPYFDRTELSFDEEFEIFEYILKTFIYEQEDGEDDSLGGMSQTKTMH
                     FEKDAELIFASFFQSYHLDLFEQQGKLHWRKFMSLLMNLHKDTPFKEVVSYRVMKVPN
                     KDEASEEYIKHVKKMKRIYSLEDESEHQALNDDKLSALAARFGGE"
     gene            13283..15730
                     /locus_tag="TV191_001100"
     CDS             13283..15730
                     /locus_tag="TV191_001100"
                     /inference="COORDINATES: protein motif:HMM:TIGR01760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HEL1507622.1"
                     /translation="MADGSVIIDTLLKTEKFNQGVGKLQGKLAGLGSKLTSIGTGLTL
                     GLTAPIVGIGAASLSTFTTFESQMNRVKAISGATASEFRKLEDQAIKLGASSVFSATE
                     VAQAQEMMASAGFKVVDILKAMPGVMSLAAVSGGDMALASEAAATAVNMFGLEAKDAA
                     HVADVFAQAAADTNAEVGDMAEALKYAGPVAGALGISLEETAAAIGIMSNAGIKGSQA
                     GTTLRTSLSRLTDPTKKMRGIMSELGLEFFDVNGKMKSLSGITKELQTKMGDLTDSQK
                     SAAISTLFGKEAMSGMLALVNSAPGALDKQTQALINSNGAAKEMADTMNSGVKGSIEE
                     LKGSLETAGISIGKILAPALTSVIGAITSLVNWFNNLSPTMQNVVVVLGSLLAAIGPV
                     VLIIGVVTTQIAAFQQGVGLVFNAVKGLQAAFAFLTSPIGLVIVAIGALIAVFVYLWN
                     TNEQFRTKIIEIWTAISNFLQPIIQFIGNFIRETWTQLATFWNENQATIMTIAQTTWS
                     FIQTIFTTAIEMIKLAVSVFLGLLQSTWSVTFNSLKVIAQVAWAFISNVFKGSLGSIL
                     AVASAIFEQIKSTIDLAMKIIQNIIKIILSAIEGDWDGVLEGIKGIVSAFGDFIQSTF
                     SNMMDTAKRLVGAGIDTVKGIFDSLWNIDLFGAGQAIINGFLNGLRSMWGAVTDFVGG
                     IASWIAANKGPISYDRVLLKPHGKAIMDGLGNSMKTNFKDIQKDVSGMADDLTRSFQI
                     KRFNGFLPEKYTTKLDELKKYAQATLGGMILAPNMAVQPTVVVNISNEADSDIIRQKV
                     NAKNAQDAIINQLFKKG"
     gene            15734..16495
                     /locus_tag="TV191_001101"
     CDS             15734..16495
                     /locus_tag="TV191_001101"
                     /inference="COORDINATES: protein motif:HMM:NF017520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEL1507623.1"
                     /translation="MFSIEFLDGERLSADERGWKVKEMSSSGLEQNVVSESPKMRSGR
                     LVYGLYHGIKTYQLVFTKIIKDTLDYSRLVDEVNYYFLRDEPYYLYRDFRKKADRVDL
                     PKKRAKVFTKSIDHQKNGLKVEFTAKLESYELPYEEDTEVQRVTWTATHSWHNKGGHR
                     LDPRYCPMKMTITVSGSGAELKVLFNGQPYFWYKKSVKQGDIFIIDGTDVEKNRYNCF
                     EDCHKQTSFLKTGNNRIDIQGASCEALFEYRLLYL"
     gene            16506..>18070
                     /locus_tag="TV191_001102"
     CDS             16506..>18070
                     /locus_tag="TV191_001102"
                     /inference="COORDINATES: protein motif:HMM:NF018329.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1507624.1"
                     /translation="MQVKTKQGVFYVNADYTVVEKQGDYPKLTCTIPIKGNETWIADC
                     QELDRLYPAGEQDEFIIINPIKVTKGSSYDLEITAIGAFHFEFVKARLYEELPERMYT
                     LDYLLDLLFKDSRFSYKLQGDYSTRRFSGFGDDNKLTLFHHLMERFQTEFKVVGKVVL
                     VNTKVGKDTGFQFRYLRNIKDTKYSVDVTNLMTYVKGYGAWFDENDHSKGRLIVDYES
                     PLSKEYGKLDGKPVVDERMSLKESLIKKCKLAVDRSVSVSLTTTLVSLKQQDYQGAAR
                     IGDSIWFIDERISIEKKIRFSVVTTYYNAYDDILKQDVTLGDKDTYSRYQSLENSSQT
                     ETNDFQKAMSSKLAEVQDDVKKTHILVSGTTRIFFSTEFPQDNPKGTIKEDDILYRNH
                     DGTTLMYRWNGVQWELVPLVNDPDRWREELEKQISEAVEKLKQEQKVINQRTDKELEE
                     FRDTLKNLSLPEEAIKKITEAIKVDDIPSIKQSFDDLKNKVSETSETARLNAEIIGTD
                     GKTRYNKNLLVGDP"
BASE COUNT         5894 a         3143 c         4123 g         4910 t
ORIGIN      
        1 acccacgcag ttactgataa aaatttattt acagagtata catttgcgac gcagcaagat
       61 gccgagaatt atatcagaga cttagagcta aacggatcta agtgtgccct ttgagtatta
      121 tgagaggaga tttgcaaaat gatagacacc gatacacttg cagcagtacg ggaggctgat
      181 catgactaaa aacgactttt taacaggttt tgtacttata cttttagctg cttgcatttt
      241 tgcagcagga tttgtgattg gatctgactg tagtagcgag cactacgagc aacaaatgac
      301 aggcttgcgt atgcagcttg ttaacacgca gcagcagctt aagcgtgcga gtgaggatag
      361 agcaaggcgg actaaaagga ttgcggatct gaccgggaat ggaggatagg gtatgatcga
      421 cgaaatcgaa ctcgacctac aaaaaccaga aatcccacag tttgtcgctg actacataga
      481 tgatatgcac aaaaacgcac gtacattgag atacgctttt aaatacatgg aaagtaacat
      541 aaaaatgcac aaatggtgtg tttttgaaag gcaagaaacg tttgttaatg cttttttata
      601 cggctacaca ataaaaaaag aaaagctgta tattgttgag atccctaatc ctaatagtgg
      661 catagaacac aaacatattg cactagcaag gttagcgaat ggaaaacttg gattttcaga
      721 gatcatagat actgattttt attcaagaga agatgtccga ctcaccgagt cagaaatccg
      781 caaagatttt gattgggcat ggagagaggg gtttgctaaa gaggtgacgg aatgagcaga
      841 gataaaacca gaatcaggaa cattgtgaag tccatgaaac agttaggtgc tagcgaagaa
      901 gagacagacg aatacatgta tctatgcgtg tttaaaaagc ctcacgtcat agctcaaatc
      961 cgtaaaaagg ctaagatttt cagaggcgaa gggtggtaac agatggcata tttacgagaa
     1021 gaaagagaaa cagttattca ttacgacgaa ttggatgact gctggacttt tgaaactaac
     1081 gtccgtaggc atattacgaa aatagaaaaa cgcatcgaac tgtacgagat tctctcagag
     1141 gaattcgatg accgaggaag gcgtatctat atctgtgcga aaatgaagac aggaactgtc
     1201 agtccctttg cgaaaccacc aagaaggaaa tagctataga atcgatttta agcttcaaaa
     1261 acatggcaag aacgcacttc tgggaacgtg aaacacctag ctaatataaa tgtaccctag
     1321 aacaatttaa atcgaaaaaa tgattagcta cataggtttt aatcggctta tgtggcatag
     1381 accgaaatta aacacagaag gatgtgatga caatctcctt acacccaaaa aatctaacgc
     1441 tggttatcgg tcaccagcta ttatccaagg cgctaatact gacatcgtgt gcctgagctg
     1501 gcttataaaa aacgaaagag agggcttttc tccacacaaa aagacgtcca tgcgaacgcc
     1561 tccttggtta tatctgttaa caccattata ccacactgag ggggctttca tgacgttttt
     1621 tcctgagatt gatatccaaa aaacaaaatc caatgccaag cgtaaattga aagagtatcc
     1681 acgctggcgg cggatagcta acgatgtaga tactcaaaaa gttacagcta cttactcatt
     1741 tgagccaagg caacctcatg gagtccatag caagcctgta gagaggttag cacttaatcg
     1801 tgtgtcagcg gagcaggagt tagatgcgat tgagcaagct gtcagcatga tactagagcc
     1861 agagaggcgc aggattttgt acgataaata cttatcacct tataaaaaag cggacaaggt
     1921 tatttataca gaattgtgta tgtcagagag cttttattat gatacgctcg atatcgcttt
     1981 attagctttt gcagagctat atagagaggg gtctctgatt gtcgagcaag gagtttttag
     2041 ctagttttta tacagtaata taatagtttt tgtacaaaat agcgtgttaa tatagtatca
     2101 tagcaaaata acaaaaagag ataaccattt taccaattga ctatttattt agtcgccaac
     2161 tttaactacg atcaaacttg ttattttgaa ggtacatggg acgtgcaggt tcgaatcctg
     2221 ccgtctcaat accagctatt tccaaaatgg aaacagttgg aaaagacaaa ccccccattc
     2281 ctttaaaggc agatacgttc tgatatgggg ctttttatga ttaactgcaa gtaaaacaag
     2341 ggtcgcaacc ttgcttgtgg ttagtagacc tagtggtcgt ttatgcacgt tcgattcgtg
     2401 caaggtctgt tgggttgatt gcaataatcc ttttgtggac gcacaacaaa aatgtgatgt
     2461 aagtcacggc taaggtttgg gcggcgatag aatagatgcg caactatcgt tgggtcacgt
     2521 ctcagagttt gcatagttaa tattaaccga tgggcacacc ctgcgtcagt gggttgttta
     2581 tggatagctt agcaaagggg ttaatgcgac caactgttta gtttggtagg cgtgagttcg
     2641 aatctcacac tattctttca ggaacatgaa ccgtgattgg aaaacggtag aggtagcgcc
     2701 ttgataattg gattgtcgac ggtctgatta tatgtgtcgg ttcaattccg actgttcctg
     2761 ttctagtcac caattgtggt ggctttttat tatgtcacga ggaggtgatg gaaaattgct
     2821 aagttaacta taaaacaaca aaaatttatt gatgagtaca tcatctgtgg aaatgcgaca
     2881 gaagccgctc ttaaggcggg ttatagcaaa aaaacggctg ggcaaatcgg tgagcagaac
     2941 ttgaaaaaac ttgaaataaa atctgccatc aacgaacggc taaaacaact cgaaagcagt
     3001 aaaatagcta gtgcaatcga gatcctacaa gttcttactg ccgttcttcg gcaggatttg
     3061 acggaggagg ttgttaccct taatcctgta acaggtgagt acgttactat gcagaaaaaa
     3121 cctagcatcg cagaagtcat aaaagctgct ggtgagttat tgaaacgtta tcctatccaa
     3181 gaacaaattg aaaaaatcaa gcaagaaaac gagttgttac gccttaaaat tgaaaccgtc
     3241 aaaggcgcca agcctgatac ccatttgatg gaaaaactgc tggaggtaat cgaagatggc
     3301 ggttaggata aaaaagttat ccacaaaaca aaaagacatc attagacgcc cttttaacta
     3361 cgaattagag gtcaatgagg gaacacccag aagtggaaag accaccgctg ggcattttcg
     3421 ttatgctagg tatctgattg agtcagaaga tgaaaatcat cttgtgactg cttataatca
     3481 agaacaagct tatcgtttgt ttattgatgg agacggtaca gggctgatgc acatctttga
     3541 cgggaactgc gaaatcaaac atgatgagcg aggagatcac ctgcttgtaa caacaccaaa
     3601 aggtaataaa agggtttatt acaagggtgg aggtaaagtt aactcagtcg gtgctattac
     3661 aggtatgtct ctaggctcag tggtcttttg tgagattaat ctactgcata tggattttat
     3721 ccaggagtgt tttaggcgta cctgggcggc taaactgcgt tatcacttag cagaccttaa
     3781 ccctcctgcg ccacagcacc ctgttattaa agacgttttt gacgtccaaa ataccagatg
     3841 gacgcattgg accatggacg ataatccaat attaactgcg gagcgcaagc aaaacattat
     3901 caatagcctc aaaaaaaatc cttatcttta taaacgagat gtactcgggc agcgggtgat
     3961 gcctcaaggt gttatttatg gtctttttga catggaaaaa aatgttctag acactttgat
     4021 tggcgagcca gtggagatgt atttctgtgc agatggtggg caatctgatg ccacatctat
     4081 gtcttgcaac atcgtaacaa gagttagaga taatggcaag ataagtttta ggcttaatcg
     4141 gacagcgcac tactatcata gtggagcaga tactggtcag gtcaaagcca tgtcaacata
     4201 cgccagagaa cttaaggctt tcattgactg gtgtgttaaa aaataccaac ttcggtactc
     4261 tgatgtcttt attgaccctg cgtgtaaggc tttgcgcgag gaattacatg ccattggtat
     4321 tctgacgact ggagcgccga acaacgctca cgacgtaaac agtaaggcga aaggtatcga
     4381 agttgggata gaacgtggcc agactttgat ttcagacggt gatttttatc tagtaaatca
     4441 caaagaggaa aaatatgatc attatcattt cctgaaggaa ttagggcttt atagccgcga
     4501 tgataaaggc aaaccaatag acgcaaacaa ccactcaatg gacgaattta ggtactcggt
     4561 caatgttttt gtgggacgat acaaaatgaa ataggaggta gtcatgttta gaaacctctg
     4621 gactaaaata aaaggggtga tgcaaaaaat gggattgata aaaggtttga aagatttgaa
     4681 cctgcaccgc gaaattgaac tgtctgataa gcattatgat agtatccaaa tttggaaaga
     4741 gttgtatcaa ggctatcacg ataaaataca cgattactat gagaaatcta tcttagatgg
     4801 tcgtaaaaag aagaagcgtt tgactttgaa tatgcctaaa gttgtgacct cagagcttgc
     4861 tacattgatt tttaatgaaa aatgtgaaat taacattggt tctgaaaatg agagtttgac
     4921 aaagctcatc actgaaacgt tagagaaaaa taattttact caggagtttc aacgcttctt
     4981 agaatatagt ttcgccttgg gaggtatggc aatcaaagca tatctcaaaa aggacggtac
     5041 tatcggtctt aattttgtac aagcggatag ttttattccc atttcgtggg ataatgctgg
     5101 gattagcgaa gccgtatttg ttgatacgca gcatcgtgga aaatacaagt acacgcattt
     5161 ggagtggcat acttgggaaa gtgagttgta tgtagttgct cacgagttat ttagaactga
     5221 caagtcaaat gatgatgttg gcattcgcgt accgataaca gagatttatc cagatttaaa
     5281 atcacaagta gtcatcgaaa aactatcaag accgctattt gtttacctca aacctaattc
     5341 ggcaaacaac attgatctat caagtccgct agggatttca atctatcaca attcgtttga
     5401 taccttgcga gcgattgata ttgcctacga tagctttgag cgtgagtttc gacttggccg
     5461 taagaggata ttggttccag cgactgccat tcgtactgta gtggatagcg aggggaattt
     5521 ccaccgctat tttgacgcaa cagacgaaac atatgaggct ttccacacag gtgaagacag
     5581 caaaattcaa gatatcaaag atattagtgt tgaattgcga gttgatgaac atattgcagc
     5641 tattaacgca ctgttgaact tacttagtat gcagattggc tttagcccag gttctttcag
     5701 tttcgatgga gtatcgggtg tcaagacagc caccgaggtt atctctgaga attctaagac
     5761 attccgcacg aagcaatctc atgaaacgat ggtagaagca acattgaaaa atcttgttgc
     5821 gattatcgtt gattttgggg atctttatgg tttgatcgag ggtgagagta agtataatgt
     5881 aactgtaacg tttgacgact ctattgcgca ggacagaacc caggacgctc agtattatat
     5941 agggttggtc gcagctgggt taatcagcaa gaaaaaagct atgatgaagc tgtttaatct
     6001 gtcagaagaa gatgcagagt tggaaatcca aactatccac gaggaaagcc ggacaacaaa
     6061 cgatatgtca attgatttat ttggtttgga cggtgatgct tagtggatta tgatactcat
     6121 atccagctgt cttttgactt aatagagctt tattctgatg tcgaacgtga attgttgacg
     6181 tcaataggtc gcaggtttgc aaaacactat gacgaaatgg tagctggcga catcatggat
     6241 tggcaaatta ggcaattact cgaagttgga gagctgagaa aagagcacat cgaaatcatg
     6301 cgaaaaagtg cacgcgtgag tcgtgagcgt atgattgaga tgctgacgga ggcaggttat
     6361 acctccgcag gaaggtatga ggattttttt aaagaggcat acgttaaagg tttaatcaag
     6421 ctcaatccat ctgctgcaga caacagcatg aggttgttgc gagtgttaaa tacttacatc
     6481 aatcaagctg aggacacact taatcttgtc aatacgacca tgttacagtc tggccaagat
     6541 acttttttag atacagtcaa tcaagttgtt gcttatgttt ctacaggtat caagacccca
     6601 caagttgcta tgcgtgacgc tctaaaaaat gctggtcaaa agggccttac agtctttcgt
     6661 gctaaaaatg gcgcccagtg gtcaacggag acttatctca atatgatcac tcggacgatg
     6721 aactctaaca tttctaacgc tatggaagat gagcgtaggc atgagtatgg tgttgattac
     6781 atcgaggtat ctagccatgc tggcgcacgt ccaaggtgtg ctccttatca aggtcggata
     6841 tattacgatg gtgtcggaga tgatccgcta gagaaatacc cgcacttctc agagacttct
     6901 tatggcgaag ctgctggatt gtttggcgtt aattgcggtc atcataaata tccttacgtc
     6961 ccaggtatga gtaaacagac ctttttccct tacagtaaaa gcgaaaacga taaaacctat
     7021 gcagagtcgc aggtacaacg taaattagaa cgggaagtta agcagctgaa acgggaacga
     7081 gcaattctaa ctgctgcgaa ggacaaagag ggggctaaat tagcttctca acgcttggag
     7141 aacaagtggc aggaattgcg tcagtttact gctcaaacag gcagaacgag acgatacgac
     7201 cgcgagaaat cgctaaatac tattttgtct gaggacaaga aaaaagccat tgtcaaagat
     7261 aatttgaaaa tcagagatga gtatcgagcg attaagaaag ctatccctga agtagctcct
     7321 aaaaatcttg aaacctatta tgatatgcgt tataatggtg gcaagatata cgaggattta
     7381 gttagggatt acaaagacta tataagatgg tctaaagctg aatttcctac taaaaaatct
     7441 tttgaagggc atattgatag tcacttaaaa gagtttccag gattgactgg taaacaatat
     7501 cagaaaaagg ctgctgactt attatctaga ccgataactg ataatatttt aggttatgat
     7561 acagattcta gacgtgttag gtatgactta gaaaataaca tttttgcttt agggcgcgtt
     7621 aaacaaggta cgattacgac tatgctgaaa ccaaaggaag gggttgatta ctttgacaat
     7681 gactggaaaa gagagtttga taatcttaaa tgatttagaa tatgtccatt gtcctgtttg
     7741 tggaactttg accgaggttt atgatatttg cgatacttgt aaatggcaga ataccggtga
     7801 gacaaatatt gatggcggtc ctaattatat tacacttgag gaagcacgac gaaggtgggc
     7861 aaatggtgaa cctttgcgca acttttttaa agaccaataa tacaagcact gtaacagtgc
     7921 tttttttgta ctcaaaaaag gagagagtaa aatgaacaaa cgaattgaaa agaagcgtcg
     7981 cacacaaatg atgttagaca gaatcttgcg cattgtagaa ttgatgtcgc aagcaactga
     8041 cgacaacttt gctatcttgg aaaagcgctt agaaaaagct gaaaaacgta acgaagagct
     8101 tatggaaatc atcttagtaa acgttaaaga ggtaaataac cgctttgacg agctagaaat
     8161 ctgccagaag attgttgaag atgatgtcgc agagctcaaa aaagctaaga aaaaaggctg
     8221 gttcagccgg aaataactta atcgtgtcga attcgatgcg gttttatttt gccctgccgc
     8281 atggcgataa actaggtaaa aataaaagaa agaggtctaa aatggctgtt attatcgtac
     8341 aaacacgagg cggagatatt gaagttccca ccccattacc agcaatgcaa gctaataaag
     8401 cgattcaaag tcaattattc gataaggagc tgactttttt atgcgtggat aatcatgctt
     8461 ttgctaaaac tgaggtttta cacgttttgg tcgaaacaga agaagatgaa gaattaccac
     8521 agtcaaaaca taaggaggaa gaaacatgct acatggatta aaacaccgtt tgtttaaact
     8581 agccccagat actggagcag gcggaggcgc tgaagttact agcgagacta acgctgaagc
     8641 tggacgagtt gagcaaacag tatcgcaaca acaagctgat ccggttgata ctgaggcaat
     8701 caaaaatcaa gcaattaatg aggttctaag tcaactaggt gtttcttcgg tagaagatgc
     8761 caaagcaaat ctagcttctt ggaatgaata tcaagaaggt cagaaaacag agtttcaaaa
     8821 aattcaagat agtttgactg tggctaataa ctctttggct gagcgcgaca ctatgattgc
     8881 tagcttacaa gctcagttag ctgctgctca aatgggagtg cctgcggaaa acacctccga
     8941 tgttatcact ttggccaata gtttggtcca cgataaaaca gacatcaatg cagcgattac
     9001 taccgtactt gagaaatatc ctcatttcaa aggaggtgat gccgatgtag ctgataaacc
     9061 taactttgtg actcaaactc agagtcaaac ggaaacgacg gaagacgctt tttttaaagc
     9121 gttaggacta acaattaagg aggactaata tgtcaatcaa ttatattact aaacatgaag
     9181 gaatattcga aaagaaacta atgcaaggcg ctttgacgtc taacttagag acaccaaaag
     9241 tcaactggtt aggtgcaaag tcttttgagc taccaaccat ctcggtgact ggctataagg
     9301 cgcacacacg ctcaaaaggg tataacgcag gtactgtatc taacgataaa aatacttata
     9361 cgctcggctt tgatcgtgac gtagagtttt ttgtggataa ggcagacgtc gatgagacta
     9421 accaagagct gtctatggct aacatctcaa acacttttat cacagagcat gcaacgccag
     9481 aagttgacgc ttatcgcttt tcgaagattg ccacaaatgc gatcgataat agccatttta
     9541 agcaggaaga tgactactct actactaatg tttatgagcg cttaaaagct gctattttgc
     9601 ctattcgcaa gtacggagct ggcaatatca ttatctatgt ctccagtgag attatggact
     9661 ttttggagcg ctcaaaggac tttacacgct caatcgcgac aacatcaccg caagggattg
     9721 atactcgtgt gacatctctt gacggagtgc agctcataga ggtttgggac gatgcccgct
     9781 ttaagactaa atttgatttt acgacaggct ttgtcaaaga tggcagcggt aaagacatta
     9841 actttttgat tgtggccaag cctgcggtta ttgcaaaagc taaatttaac tctatttatc
     9901 tttttgcacc aggtcagcac accgaagggg acgggtatct atatcaaaat cgcttgtatc
     9961 acgacctttt tgtgcttaaa tctaaacaag atggggttta tgtatcccat aaatcagctt
    10021 aggaggttaa cgatgaaaac atacgagaag gacaatcaag tctataaagt acaagaaggc
    10081 agcgagctgg aaattcagct gattgccgac ggctttaaag aaattattga agcaaacgaa
    10141 aaggaaactg atatcactaa aatgaagctt gataagctaa aggcttatgc tgaaaatgaa
    10201 ggcattataa ttcctgaaga tattaagaaa aaagaagatg ttttagcttt tattaaggaa
    10261 cagcagcaga gaggtgagta gtgatgctca cctttgattt ttacaataag ggatattgtg
    10321 gctcacagct gaatgaagaa aagttcgggg agctgtcaaa acgtgctgag cgtaaaattt
    10381 tggcacttat tggcttgaaa aaggagcaag tgaagaattt gccacttgat attttagagg
    10441 cggtaaaaat ggctgtctgc gcccaaattg agtatcttaa cgcaataggc gttgaaagtg
    10501 ctatcggagt aacctctgta acccaagcta aagtcggcaa ttttagttac acagacggaa
    10561 agaaagcgac tgtatcagct agtgttggct ctgttggtgt tagccctgac gtgctagact
    10621 atctgcttcc gagtggattg ttatacaagg gggtgaatac gagatggtaa aagaagtcaa
    10681 acctatccct aaagagttat tagttgacac agttacttat ctagcagttg gcaacaaaga
    10741 cagctgggga gcagaaacgg tagtatctac agaattgtca caggtgttag tacaacctag
    10801 aagcagtatc caacgtgggc aacaaaacga gagtaatagc tacgagttgt tactcttttt
    10861 tgattgtgta aactcgttac cagtagatca tcagtttaag gttgacgaca aaattagtta
    10921 tctaggaaaa gagtatcgta tcgcaagtgt tgaggtacta aaagcttttg accagtcgcc
    10981 acatcactat gaggtgatgc tagaatgata ggttttaagg ttgaagtcat ctttaacgct
    11041 agtaaattga ttgccaagag tgaagcatct gcaaagacag ctcgctttgc tttaagtggt
    11101 caaatcaaaa aggatagtga caagtatatt cctgctcgtg agtggaatct gcgagatagc
    11161 ggaagagtaa ctgaacgctc agtatcttgg catacaccgt acgctagacg actctactac
    11221 aatcctcagt ataactttag caaggataag aatccgaatg cacaaggcaa gtggtttgag
    11281 gttgctaaag caaatcatgc agagcattgg tatgagctaa caaagaaagc ctatggtgct
    11341 gagtttagag gagattaatc atgacattta ttgatttttt gctcagaaaa gttcaagaag
    11401 tgagcggagc ggaaccggtc cttggcatta tggggaatag tgataaggtt gctattatcc
    11461 ctatggctgg aaattttgac aatcgagctc ttgacgaaag taagattagg atttttactt
    11521 tccaagtttt ggccaagagt aaaaaacagc aggaagcttt tttgacaaca gaaaacttgg
    11581 tcaatggtct agacggtcta tcaaatgagc cgtttactgg aggatatctc attaagctgg
    11641 agtgtacgac gaccactaac tttgttgaaa aagatagtga caaaaattat ttatatacag
    11701 ctcttttcag agcagaatta ggaggataag aaatggcagc agataagcca actttttatt
    11761 tacaatccga gcataagctc gaaatttcag aagatggaaa aacttggatg cgactagcag
    11821 gtggtatcag tgaattagaa ccagacggaa atgaagaagt atcacaagat gcttatcttg
    11881 acggctctga atctgatgtt acaggaggtc agctagtact agccttaact ggacatcgtc
    11941 tagtaggaga taaagctcaa gactggatct atgcacgtca attccgatat gggggcaaac
    12001 gtcgtggttt tacgcgttgg acattgccag gaggaaaaac acagtttacc tttgcctcta
    12061 cgtttgcaaa tatcaaaggt ccatcaggag cggctaacgg taaaggtgaa attgaatttg
    12121 aaatccattc gaacgaaaca cttgtaccta ataaagtagt tgtagaagtc actaagacaa
    12181 acaaagaact tgcgtctgaa gcacttggtt tagaacgtca agagcgataa gtagaaagga
    12241 tagtcagcaa tggtgagaca gtttgaattt aagaaaacgg ttgaagaaat tgagattgca
    12301 ggggaaatct acttactgcc tcttgatgat gataacctct tacgtatcca acgtgacttt
    12361 attagttacg gaaaagagat cgaagaactc caaaaagttg aggtagaaaa aggagatcca
    12421 gacgatctgg cggataatca taagcaacag cttttagtaa tgaaaaaggt catcgagtca
    12481 ccatttggag aagggagttt tgagaaactt tacgaagcat cagggcactc tttaatgaat
    12541 atggttgact tattggatta tcttgttgag ttagtcgctg aaaaagttga gcaaaataag
    12601 gctcgtgcca ctaaagcaaa agagaagtat tactcctcga agcgcaagaa aaagtaggta
    12661 gcttatgaag ttgacagaaa catatgaagt tcttgctgat gcttttgaat ttggcggtca
    12721 tatcgtaact gttgacttgg cttttgatgt cgtgttgcga gtcatggagc ttcttgccga
    12781 cgcagaagtc aatgactacg ctaaaattgt ctggactttg gatatgctct tgccatattt
    12841 tgatcgtacg gagttaagtt ttgatgaaga atttgaaatt ttcgaatata tcctaaagac
    12901 gtttatctat gaacaagaag acggagaaga tgacagttta ggaggaatgt cacaaacgaa
    12961 aacaatgcat tttgaaaagg atgcagagtt aatctttgcg tccttttttc aaagttatca
    13021 tcttgaccta tttgaacaac agggaaaatt gcactggcga aaatttatgt cactgctcat
    13081 gaatctgcat aaagacactc cttttaagga agttgtcagc tatcgtgtca tgaaagtgcc
    13141 taataaagat gaagcatcgg aagagtatat caaacacgtc aagaagatga agcgtatcta
    13201 ttcgctagaa gacgaatctg agcatcaagc gctaaatgat gacaagcttt cagcgttagc
    13261 agcaaggttt ggaggtgagt agatggcaga tggtagtgtt attattgata ccctgctaaa
    13321 gactgagaaa tttaaccaag gtgtagggaa actacaaggt aaattagctg gattaggatc
    13381 aaagttgacc agcattggta ccggtctaac tctaggctta actgctccta ttgtaggaat
    13441 cggagcggca tcgctcagca cgtttactac atttgaaagt caaatgaatc gtgttaaggc
    13501 gatttctgga gcaacagcaa gtgagttcag aaaactagaa gaccaggcta tcaaacttgg
    13561 agcttcctct gtttttagtg cgacagaagt agcacaagct caagaaatga tggcttctgc
    13621 aggttttaaa gtcgtcgata tcttaaaagc aatgccgggt gttatgtctc tagctgctgt
    13681 atctggtggg gatatggcat tagcaagcga ggcagccgca acagctgtca atatgtttgg
    13741 acttgaagct aaagacgcag cccatgttgc agatgttttt gcacaagctg ctgcggatac
    13801 taacgcagaa gttggagata tggcagaagc cctaaaatac gccggacctg ttgctggggc
    13861 tttagggatt agcttggaag aaaccgcggc agcaattggt atcatgtcta atgcaggcat
    13921 taaagggtca caagcaggaa caactttgag gacaagcctt tcacgactta cggatccaac
    13981 taaaaagatg cgaggaatca tgtccgaatt aggacttgaa tttttcgatg ttaatggaaa
    14041 aatgaagtcc ttatctggta ttaccaaaga acttcaaacc aaaatgggtg atttaactga
    14101 tagtcaaaag agtgcagcta tctctacttt gtttggtaaa gaagcaatgt ctggaatgct
    14161 tgccctagtt aattctgctc ctggcgcatt agacaagcaa acacaagcac ttatcaattc
    14221 aaatggtgct gctaaagaaa tggcagacac catgaatagt ggtgtcaagg gatcgattga
    14281 ggagcttaaa ggttcgcttg agactgctgg aatctccata ggtaaaatat tggcgccagc
    14341 cctaacgtcg gttatcgggg cgataacaag ccttgtgaat tggttcaata acctaagtcc
    14401 gacaatgcaa aacgtggtag ttgtactcgg aagtttactt gctgccattg gaccggttgt
    14461 ccttattata ggggttgtta ctactcagat agcagctttc cagcaaggcg tcggactagt
    14521 ctttaatgct gtcaaaggat tacaagctgc ttttgccttt ttgacgagtc ctatagggtt
    14581 agtcatcgta gccataggtg cactaattgc cgtatttgtt tatttgtgga atacaaacga
    14641 acaatttaga acgaagatca ttgagatttg gacggctatt tcgaactttt tacagcccat
    14701 catacaattt attggtaatt tcataaggga aacgtggact caattagcta ctttttggaa
    14761 cgaaaatcaa gcaactatta tgacaatagc ccagacaact tggtcattta tccagacgat
    14821 atttacaaca gcaattgaaa tgataaaatt ggccgttagt gtttttttag ggttattgca
    14881 atcaacgtgg tctgtaactt ttaattctct taaggttatc gcacaggtcg catgggcttt
    14941 tatttccaat gttttcaagg gaagtttagg gtccatactt gcggttgcat ctgctatatt
    15001 tgagcaaatt aaatcaacga ttgatcttgc gatgaaaatt attcaaaata tcatcaaaat
    15061 catactatcc gcgatagaag gtgattggga cggtgtatta gaaggtatca aaggaattgt
    15121 ttccgcattt ggagatttta ttcaatcaac tttctcaaat atgatggata ctgctaaacg
    15181 cttagtcgga gctggaatag ataccgtaaa aggaattttc gattctttgt ggaatattga
    15241 cttgttcgga gccggtcaag cgattattaa tggattctta aatggtttgc ggtctatgtg
    15301 gggagctgtc acagatttcg ttggcggtat tgcaagctgg attgcagcaa acaaaggtcc
    15361 catctcatat gatagggtac tattgaagcc gcatggaaaa gctattatgg acggactcgg
    15421 taatagcatg aaaactaact ttaaggacat tcagaaagat gtttctggca tggctgacga
    15481 tttaacaaga agttttcaaa tcaaaaggtt caacggtttt ttgccagaaa agtatactac
    15541 taagcttgat gagcttaaaa aatatgcgca agccacgctt ggcggaatga ttttagcccc
    15601 taacatggca gttcaaccga cagtcgttgt taacatcagc aatgaagcag atagcgatat
    15661 catcaggcaa aaagtcaatg ctaagaatgc acaagatgct attattaatc agttattcaa
    15721 gaaagggtaa aacatgttca gtatagagtt tttagacgga gagcgactaa gcgccgatga
    15781 acgaggatgg aaagttaaag agatgtcctc atcaggactt gaacaaaacg tcgttagcga
    15841 gtctcctaaa atgcgttctg gtcgccttgt ttatggtctt tatcatggca tcaaaactta
    15901 tcaacttgtt tttacaaaaa tcattaaaga tacccttgat tatagccgtt tagtagatga
    15961 agttaattac tattttttac gtgatgaacc atactatctt taccgcgact ttagaaagaa
    16021 agctgatcgg gtggacttgc cgaagaagcg ggcgaaggtg tttactaagt caatcgacca
    16081 tcaaaaaaat gggcttaaag ttgaatttac agctaagctg gaatcttatg aactacccta
    16141 cgaagaagat actgaggttc agcgggtcac ttggacggca acacattcat ggcacaataa
    16201 gggagggcat cgccttgacc ctcgttattg cccaatgaag atgaccataa cagtatcagg
    16261 ttcaggagct gaacttaagg tgctatttaa cggtcagcct tatttttggt ataaaaaatc
    16321 agttaaacaa ggggatatct ttatcattga tgggacggac gttgaaaaaa atagatacaa
    16381 ttgttttgaa gattgccata agcaaacctc ttttttaaaa acaggaaata acagaataga
    16441 tattcaagga gcttcgtgtg aagctctttt tgaatataga ctactgtatt tgtaggaggg
    16501 ttagtatgca ggtaaaaaca aagcaaggtg ttttttatgt taacgcagac tacaccgtcg
    16561 tcgaaaaaca aggtgactat cctaagctaa cttgtactat tcctattaag ggaaatgaga
    16621 cttggatagc agattgccaa gaacttgacc gcttataccc agctggggaa caagatgaat
    16681 ttattattat caatcctatt aaagtcacta aggggagttc gtatgatttg gaaattacag
    16741 cgataggagc ctttcatttt gaatttgtaa aggctcgtct atatgaagaa ctaccagaac
    16801 gaatgtatac tttagattac ttgctcgatc tcctgtttaa agacagccga ttcagttata
    16861 agctacaagg tgattattct actagaaggt tcagtggctt cggagatgat aacaaactga
    16921 ctttattcca tcatttaatg gaacgatttc aaacagaatt taaagttgtt ggcaaggtcg
    16981 ttttagttaa cacaaaagta ggtaaagata caggatttca gttccgctat cttagaaata
    17041 tcaaggatac aaagtactcg gtagacgtaa ctaacctgat gacatacgtt aaaggatatg
    17101 gagcctggtt tgatgaaaat gaccattcaa agggaagatt aattgttgat tatgagagcc
    17161 ccttatccaa agagtatggc aaacttgatg gtaagcccgt tgttgatgaa cgaatgagtt
    17221 taaaagaaag tcttatcaaa aaatgtaagc tagccgtaga tcgctctgta tctgtcagct
    17281 taacaacgac tttagtctct ttaaaacaac aggattatca aggtgcggcg agaataggag
    17341 actctatttg gtttattgac gaacgtatat ctattgaaaa aaagattcgg ttcagcgtag
    17401 taacaactta ctacaatgca tatgatgata ttttaaagca ggacgttact ttaggtgata
    17461 aagataccta ctctcgatat caaagtttag aaaactcttc tcaaacagag acaaatgatt
    17521 ttcaaaaagc gatgagtagc aaacttgcag aagttcaaga tgatgttaaa aagacgcata
    17581 ttttagtatc tggcactact aggattttct tttctacaga gtttcctcag gataatccta
    17641 agggaactat aaaagaagat gacattttgt accgtaatca cgatgggaca acattgatgt
    17701 acaggtggaa tggtgttcaa tgggaattag tcccgttggt aaacgatcca gatcgttggc
    17761 gtgaggaact ggagaaacaa atctctgagg ctgtcgaaaa gctcaaacaa gagcaaaaag
    17821 taatcaacca gagaaccgat aaagagctcg aagagtttag agatacgctc aaaaacctat
    17881 ctttaccaga ggaagccatt aaaaaaatca cagaggctat caaagttgat gatatcccgt
    17941 cgattaaaca gtcatttgat gacttaaaaa ataaagtcag cgagacaagc gagaccgcac
    18001 gattaaacgc tgagattatc gggacagatg gcaagacccg ctacaacaaa aatttgctag
    18061 tcggcgaccc
//
LOCUS       DARYXW010000040        17973 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.040, whole genome shotgun sequence.
ACCESSION   DARYXW010000040 DARYXW010000000
VERSION     DARYXW010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17973)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17973)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17973
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.040"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            36..1694
                     /locus_tag="TV191_001103"
     CDS             36..1694
                     /locus_tag="TV191_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1507625.1"
                     /translation="MTVLGTKACKRLGLAAVTLASVAALMACGNKQSASTDKKSEINW
                     YTPTEIITLDISKNTDTYSALAIGNSGSNLLRADAKGKLQPDLAEKVDVSEDGLTYTA
                     TLRDGLKWSDGSDLTAEDFVYSWQRMVDPKTASEYAYLATESHLKNAEDINSGKNPDL
                     DSLGVKADGNKVIFTLTEPAPQFKSLLSFSNFVPQKESFVKDAGKDYGTTSEKQIYSG
                     PYIVKDWNGTSGTFKLVKNKNYWDAKNVKTETVNVQTVKKPDTAVQMYKQGKLDFANI
                     SGTSAIYNANKKHKDVVPVLEATTAYIVYNQTGAIEGLNSLKIRQALNLATDRKGIVS
                     AAVDTGSKPATALVPTGLAKLSDGTDLTEHVAPGYKYDDKEAAKLFKEGLAELGKDAL
                     TITITADADAPAAKSAVDYIKETWETALPGLTVEEKFVPFKQRLEDTKNQNFEVAVVL
                     WGGDYPKGSTFYGLFKSGSAYNYGKFTNADYDAAYNKALTTDALNTDAAADDYKAAEK
                     ALYDNALYNPLYFRSGEGLQNPSIKGLIRNSTGLNVDFTYAYKD"
     gene            1863..2777
                     /locus_tag="TV191_001104"
     CDS             1863..2777
                     /locus_tag="TV191_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1507626.1"
                     /translation="MIKYLLKRVAILVVTLWVVITLSFFLMQVMPGTPYNSPKLTDDM
                     IAMLNQQYGLDKPLWQQYLKYLFDILHGDFGTSYQSINQSVTTLISQRLGVSVHLGVQ
                     ALIVGISSGLAVGAVSARNKNNSIDAILSVISTLGISMPSFIIGLLLLDYLGFKWNLL
                     PLSGWGSFGQTILPTLALAIPVFAQVTRFFRSEMIETLSTDYIQLARAKGLTKRQVTR
                     RHAYRNSMIPVLTLVGPMAAGILTGSALIEQIFSIPGIGQQFVTSIPTKDYPVIMGTT
                     IVYALMLMVAILATDMIISIADPRVRLG"
     gene            2787..3818
                     /locus_tag="TV191_001105"
     CDS             2787..3818
                     /locus_tag="TV191_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004347296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1507627.1"
                     /translation="MLEETKSFKLVGAGSLATQEKIEKPALSFLQDAWRRLKHNKLAV
                     IAMGFLAVLLLFSIGSLFVVSTDDANSFNSKEVSIYRNLPPKLSSSLPFWNGTITYAG
                     NTEPNDAYADQGVPEDKAFLLGTDNLGRSIGKRITVGIRISLLIAIVATLIDLVIGVT
                     YGLVSGFVGGKTDMVMQRIIEIISSIPNLVIVTMLGLLLGNGVTSIIISIAIVGWTSM
                     ARQVRNLTLSYRERDFVLASRALGESNIRIAFKHVLPNISGIIIVQIMMTVPSAIMYE
                     SVLSAINLGVKPPTASIGSLITDAQESLQYYPYQVLLPAFALVLISLAFILLGDGLRD
                     AFDPKSSDE"
     gene            3830..4876
                     /locus_tag="TV191_001106"
     CDS             3830..4876
                     /locus_tag="TV191_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1507628.1"
                     /translation="MTNETILSVKNLHVDFKTYAGDVKAIRDISFELKKGETLAIVGE
                     SGSGKSVTTRTLMGLNAKNASISGNICFKGKQLNELKEEEWVKVRGNEIAMIFQDPMT
                     SLDPTMTIGMQIAEAIMIHQSIHKTEALKRALDLMRQVGIPNAEEHLKDYPHQWSGGM
                     RQRAVIAIALAANPDILIADEPTTALDVTIQAQILKLMKDIQSQTASSIIFITHDLGV
                     VAGMVDRVAVMYAGKIVEYGTVDEVFYHPQHPYTWGLLNSMPTTATAAGSLRSIPGTP
                     PDLLNPPKGDAFAARNEFALDIDHIKEPPMFKVSDSHYAATWLLDERAPKITPPFPIR
                     KRWAKWQEMEERKA"
     gene            4876..5811
                     /locus_tag="TV191_001107"
     CDS             4876..5811
                     /locus_tag="TV191_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1507629.1"
                     /translation="MTEARKKLIEVKNVSLTFNKGKKNEVKAIDRLSFDIYEGEVFGL
                     VGESGSGKTTVGRAILKLYDISDGEIIFNGENVSQLKGKKLHSFRKHAQMIFQDPQAS
                     LNGRMKIRDIVAEGLDIHGLTASKAEREARVQELLKLVGLNQNHLTRYPHEFSGGQRQ
                     RIGIARALAVKPTFIIADEPISALDVSIQAQVVSLMQQLQKKRGLTYLFIAHDLSMVK
                     YISDRIGVMHWGKMLEIGTSDEVYNHPIHPYTKSLISAIPEPDPEKERKRIAEVYDPS
                     QELDGQERQMHEITPGHFVLATQAEAEQYRAECGL"
     gene            complement(6440..8122)
                     /locus_tag="TV191_001108"
     CDS             complement(6440..8122)
                     /locus_tag="TV191_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEL1507630.1"
                     /translation="MTNISLRPNEVGVYAIGGLGEIGKNTYGIEYQDEIIIVDAGIKF
                     PEDDLLGIDYVIPDYSYIVDNLERVKALVITHGHEDHIGGIPFLLKQANVPIYAGPLA
                     LALIRGKLEEHGLLRDAVLYEINHNTELTFKHMSVTFFKTTHSIPEPLGIVIHTPQGK
                     VICTGDFKFDFTPVGDPADLHRMAALGKDGVLCLLSDSTNAEIPTFTNSEKVVGQSIM
                     NIIEGIHGRIIFASFASNIYRLQQAAEAAVKTGRKIAVFGRSMEKAIVNGIELGYIKV
                     PKGTFIEPNEIKHYHASEILIMCTGSQGESMAALARIANGTHRQVSLQPGDTVIFSSS
                     PIPGNTVSVNKLINTIQEAGVDVIHGKVNNIHTSGHGGQQEQKLMLSLIKPKYFMPVH
                     GEYRMQKVHAGLAVDIGIPEENIFIMENGDVLALTSDSARIAGHFNAQDIYVDGNGIG
                     DIGTAVLRDRRDLSEDGVVLAVATVDFETQMILAGPDILSRGFIYMRESGELIRESQR
                     VLFNAIRIALKNKDASIQSVNGAIVNALRPFLYEKTEREPIIIPMVLTPDSQ"
     gene            complement(8124..8354)
                     /locus_tag="TV191_001109"
     CDS             complement(8124..8354)
                     /locus_tag="TV191_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEL1507631.1"
                     /translation="MIYKVFYQETKERSPRRENTQALYLDIDAASELEGRIKARKMVE
                     EHTDYNVEFIELLSDKHLDYEKETGVFTLTEF"
     gene            8640..9338
                     /gene="tsaB"
                     /locus_tag="TV191_001110"
     CDS             8640..9338
                     /gene="tsaB"
                     /locus_tag="TV191_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEL1507632.1"
                     /translation="MKTLAFDTSNKALSVALLDDGTLLADLTINVKKNHSISLMPAID
                     FLMSSADLKPKDLDRIVVAEGPGSYTGLRVATATAKMLAYSLSIDLVGVSSLYALAAS
                     TCRENPDSLVVPLIDARRRHVYVGYYHHQKAVKQDKYASFDAVLAELVSCDHVIFVGE
                     VEGFAEDIRSALPEAKIKPSLPSAFEVGLLGSSLSADNVAAFVPQYLKRVEAEENWLK
                     THAAGDDSQYVKRV"
     gene            9341..9766
                     /gene="rimI"
                     /locus_tag="TV191_001111"
     CDS             9341..9766
                     /gene="rimI"
                     /locus_tag="TV191_001111"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEL1507633.1"
                     /translation="MMSIQEKAAAVYQVLKEVYGQSPWTLKQIVSDMQQEHVDYFTFY
                     HQETLLGFLAIQQLPGEMEITNLAVLPSYQGQGIASWLMGQLDGFEGVIFLEVRASNH
                     RAQQLYLKHGFEVVGQRSNYYHDPIEAALIMRREGKNDR"
     gene            9756..10772
                     /gene="tsaD"
                     /locus_tag="TV191_001112"
     CDS             9756..10772
                     /gene="tsaD"
                     /locus_tag="TV191_001112"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEL1507634.1"
                     /translation="MTDRYILAVESSCDETSVAILKNDNVLLTNIIASQVESHKRFGG
                     VVPEVASRHHVEVITTCFDDALKEAQLEASDLTAVAVTYGPGLVGALLVGLAAAKAFA
                     WANDLPLIPVNHMAGHLMAAREQGELEYPLMALLVSGGHTELVYVTEPGEYHIVGETR
                     DDAVGEAYDKVGRVMGLPYPAGREIDQLAHQGTDTYHFPRAMMKEDHLEFSFSGLKSA
                     FINLHHNAQQKGEELVLEDLCASFQAAVLDILLAKTKKALKQYPSKMLVVAGGVAANQ
                     GLRERLAEEITDIAVVIPPLRLCGDNAGMIALAAVVEYEKGHVAGLDLNAKPSLAFDS
                     FHQQ"
     gene            10794..11822
                     /locus_tag="TV191_001113"
     CDS             10794..11822
                     /locus_tag="TV191_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HEL1507635.1"
                     /translation="MFYLLLPPLICSVVFLAVYIKEPRTLWLGASFVTTLGVSLLCAM
                     IYIFSIEEKLQGVGILVLGVIGFLAIVWLMSSPFILLLFLSFNGIRLIKREGLSFRNL
                     LLIGSAVLLFVHPFISRLLLESIGDSKLLRIMYETSDLLILYLLLIVSVYTISSMLNT
                     FYFRKTKEDYIIVLGSGLNGDQVTPLLASRINKGIQIYQKNPGSKLIMSGGKGADELI
                     AEGEAMCRYAIQQGIKSEDILVENQSRNTRENILLSKQLIPSGASFCLVTNRYHLFRA
                     LLLAKELALPCRCYGAKTKLYFSMNAFIREIVGYLQLKKKQHLLAMLILTVGYIAIRV
                     VMIYMLHI"
     gene            complement(12217..12486)
                     /gene="rpsN"
                     /locus_tag="TV191_001114"
     CDS             complement(12217..12486)
                     /gene="rpsN"
                     /locus_tag="TV191_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001085658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEL1507636.1"
                     /translation="MAKKSKIAKYHKQLQLIEQYADLRRELKAKGDYEALRKLPRDSN
                     PNRLKNRDRIDGRPHAYMRKFGVSRINFRELAHKGQLPGITKASW"
     gene            complement(12680..13852)
                     /locus_tag="TV191_001115"
     CDS             complement(12680..13852)
                     /locus_tag="TV191_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEL1507637.1"
                     /translation="MILYDTIIIGGGPAGMMAAISSSYYGYKTLLLDKNKRLGKKLAG
                     TGGGRCNVTNSGSHDELIAGIPGNGRFLYSVFSQFDNHDIIAFFKENGVTLKEEDHGR
                     MFPTTDQSKTIINALEQKIKSLGAQVLISTEIVSVKKRNNLFYLKSVDQTFSCERLIV
                     ATGGKSYPSTGSTGFGYDIARHFNIAVTELEAAESPLLTDFPHKALQGISLADVTLSC
                     GKHQITHDLLFTHFGLSGPAALRLSSFVKGGDIAELDLLPQTSAAELLSYLAQHREKA
                     LKNALKTLMPERVADFLAKGYPEKGKQLTPTQTQELVNRIKQLPIPITGKISLAKSFV
                     TKGGIDLKEINPKTLESKKVAGLYFAGEVLDVNAHTGGFNITAALCSGWVAGSSQS"
     gene            13978..14508
                     /locus_tag="TV191_001116"
     CDS             13978..14508
                     /locus_tag="TV191_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HEL1507638.1"
                     /translation="MAIEKTVSELADILGVSRQAVNNRVKSLPEEDLDKNDKGVTVVK
                     RSGLVKLEEIYKKTIFDDEPISEETKQRELLEILVDEKNTEITRLYEQLKAKDSQLAA
                     KDEQMRIKDVQIAEKDKQLDQQQQLTAKAMADKETLKLELEEAKAEADQVRLQAEEIQ
                     SEMGPKKGFLNRLFGK"
     gene            14553..15140
                     /locus_tag="TV191_001117"
     CDS             14553..15140
                     /locus_tag="TV191_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEL1507639.1"
                     /translation="MKQLEAYIAFDMEFNTVNEVSHIIQLSAVKWHKHQEVDSFDSYV
                     YTAVPLQSFINGLTGITSDKIVSAPKVDEVLDAFKQFVGDTPLIGYNAQKSDLPILAA
                     NGLDLSAQYAVDVFDEAYERRSSDLNGIANLRLQTVADFLGIKGRGHNSLEDARMTAR
                     VYEAFVEFDDNKSYLNKQKEAIADNPFAALGGLFD"
     gene            15244..15966
                     /locus_tag="TV191_001118"
     CDS             15244..15966
                     /locus_tag="TV191_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEL1507640.1"
                     /translation="MSDIYSTGELAKAAGVTVRTVQYYDKRGILLPSQLTEGGRRIYT
                     ESDLERLKIICFLRDLDFSIEQIKRVLAEDNVMAVLDLLLVDHIQQLEQDLRTKKHQL
                     DTAVKLLSGIRCSSSHSIKNLSDMSLTMNNQKAWRRLQLKMFSNIALAILVHVMLVLL
                     TSYFHLSWLVWIEAPLWIIFFTLLIVYFRKQFEYLCPNCHTIFEPDFKEFALAGHTPR
                     TRRLTCPHCHQKSYCLELAKEK"
     gene            complement(16008..16307)
                     /locus_tag="TV191_001119"
     CDS             complement(16008..16307)
                     /locus_tag="TV191_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016503193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEL1507641.1"
                     /translation="MMNMQNMMKQAQKLQKQMEQKQADLAAMQFTGKSAQELVTATFT
                     GDKQLVSIDFKEAVVDPEDIETLQDMTAQAINAALAQIDEATKKTLGAFAGKLPF"
     gene            16705..17292
                     /locus_tag="TV191_001120"
     CDS             16705..17292
                     /locus_tag="TV191_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507642.1"
                     /translation="MTTTKQSKTTLAARYLKLGLTSAMFAGGAFLALGSAPAVSASTH
                     AGNDQPATQRLTDQEIYERAQKLDLPDYVRGSIYGILNQNSSVTYPKDIAGLEQSEAP
                     QPPAAPQLTDQDAQKLDLPDYVRGSIYGILNQNSSVTYPKDIAGLEQSEAPQPPAAPQ
                     LTDQDAQQLDLPDYVRGSIYGILNQNSSITYPRDY"
     gene            17431..>17973
                     /locus_tag="TV191_001121"
     CDS             17431..>17973
                     /locus_tag="TV191_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1507643.1"
                     /translation="MTYKILLVDDELEIIDINERYLQQAGYRVTTASDGSQALELFHK
                     DQYDLIISDVMMPNMDGYDFIGEVLLEKPDQPFLFITAKTSEPDKIYSLSLGADDFIS
                     KPFSPRELVLRVKNILNRIYGKANQADSLVIGDLVMDHSTRRVTVANQDLNLTNKAFD
                     LLWILANHLNHVFSKTELYER"
BASE COUNT         4974 a         3628 c         4204 g         5167 t
ORIGIN      
        1 attttaaata actattttgt taggaggaag gttatatgac agtactagga acaaaagcat
       61 gtaagcgtct gggcttagcg gcagttacgc tagcctctgt tgctgccttg atggcttgtg
      121 gaaataagca atcagcgtca acagacaaaa agagtgagat taattggtat acgccaactg
      181 agatcatcac acttgatatc tcaaaaaata cagataccta ttctgctttg gctattggta
      241 attctggcag taaccttttg cgtgctgatg ctaaggggaa attacagcct gatttggctg
      301 aaaaggttga tgtgtcagag gacggcttga cctatacagc aaccctgcga gatggcttga
      361 aatggtctga tggtagtgat ctaacagcag aggactttgt gtacagctgg cagcgaatgg
      421 tcgatcctaa gacagcctca gagtacgctt acttggcaac tgagtcacat ctgaaaaacg
      481 cagaggacat taatagcggg aaaaatcctg atctagactc tctaggggta aaggctgatg
      541 ggaataaggt tatttttacc ttaacggagc cagcaccaca atttaagagc ttgctgtcct
      601 tctctaactt tgttcctcaa aaagaatcct ttgtcaagga cgctggcaag gactatggga
      661 caacatcaga aaaacaaatt tattctggtc cttatattgt caaggactgg aatggcacta
      721 gcggaacctt taagctagta aagaataaaa actattggga cgccaaaaac gtcaaaactg
      781 agacagttaa tgttcaaacg gttaaaaagc cagatacagc tgttcaaatg tacaagcaag
      841 gtaagctaga ctttgcaaat atttctggta cctcagctat ttacaatgct aataaaaagc
      901 ataaggacgt tgttccggtt cttgaggcaa caacagccta tatcgtatat aaccagacag
      961 gagctattga aggcttgaac agtcttaaaa ttcgtcaagc cttgaatttg gcaacagacc
     1021 gtaagggaat tgtatctgcg gctgttgata caggctcaaa gccggctaca gcgctggttc
     1081 ctacaggtct tgctaaatta tctgacggaa cagatctaac agagcatgtg gcacctggct
     1141 ataaatacga tgacaaggaa gctgcaaagc tcttcaagga aggcttggca gagctgggca
     1201 aggatgcctt gacaatcacc atcacagctg atgctgatgc gccggctgcc aagtctgcag
     1261 tggattacat caaggaaacc tgggaaacag ctcttcctgg cttgaccgtt gaagagaaat
     1321 ttgttccttt caagcaacgt cttgaggata ctaaaaacca aaactttgag gttgcagttg
     1381 ttctttgggg tggtgattat ccaaaagggt ctaccttcta tggcttgttt aaatcagggt
     1441 ctgcttataa ctatggtaaa tttacgaatg cagactatga tgcggcctac aacaaggctc
     1501 taacaacaga tgccttgaat acagatgcgg ctgctgatga ttataaggcg gcagaaaaag
     1561 ccctttatga caatgccctt tacaatcccc tttacttccg tagcggtgaa ggcctgcaaa
     1621 atccaagcat caaaggtctt atccgtaatt caactggtct aaatgttgac tttacttacg
     1681 cttataagga ctagcaataa tattattgta agcctatact gacctagcaa ggccacagct
     1741 ccttgatggg aagtgtttaa gagaagctta gggctagcta ggagtgtcta tcctgtaggc
     1801 cttggcaagc atattgcaag aattggtctt aaccagttct tgcttttggt tagaggaaaa
     1861 atatgattaa atatcttttg aagcgagtgg ctattttagt agtgacactc tgggtggtga
     1921 ttaccctgtc cttctttttg atgcaggtga tgcctggaac accctataac agtcctaaat
     1981 taactgatga catgattgct atgctgaatc agcagtacgg cttagataag cctctttggc
     2041 agcaatattt gaagtatttg tttgatattc ttcatggtga ctttggcacc agctatcagt
     2101 cgattaatca atcagtgaca accctgatct cgcagcgtct gggggtatct gtgcacttag
     2161 gagtacaggc gcttattgtt ggtattagct ctggcttagc tgttggtgct gtctcagcgc
     2221 ggaataaaaa taatagcatt gatgccattt taagtgttat ctcaacgctt ggtatttcca
     2281 tgccgtcctt tatcattggc ttgctgctgc tggattattt gggctttaaa tggaatttac
     2341 ttcccttgtc tggctgggga agctttgggc aaacgatttt gccgacgctt gctttagcta
     2401 ttccggtctt tgctcaggtg acccgttttt tccgcagcga gatgatcgag accttatcga
     2461 cagattatat tcagctagct agggcgaagg gcttgactaa gcgtcaggtg actcgtcggc
     2521 atgcttaccg caattcgatg attcctgtgt taaccttggt tggtccgatg gctgctggta
     2581 ttttgacggg atcagccctg attgagcaga ttttttccat tccggggatt gggcagcagt
     2641 ttgtgacctc tattcccacc aaggattacc cagtgattat gggaacaacg attgtctatg
     2701 cgctaatgct gatggttgct attttggcaa ctgatatgat cattagtatc gcagatccac
     2761 gtgttcgttt gggataggag agtgctatgc tagaagaaac aaaatcattt aagcttgttg
     2821 gagcaggtag cttagcgaca caagaaaaaa ttgaaaagcc ggcgctttcc tttcttcagg
     2881 acgcttggcg taggctaaag cacaataaac tagctgttat tgcgatgggg tttttagctg
     2941 tgctgctttt gttttctatt ggttctttat ttgttgtatc tacagatgat gccaatagct
     3001 ttaacagtaa ggaggtaagc atataccgta acctgccgcc aaagctaagc agcagcttgc
     3061 cattttggaa tgggaccatt acctacgctg gtaatacaga gcccaatgac gcttatgcgg
     3121 atcaaggggt cccagaggac aaggccttct tactcgggac ggataatctg gggcgcagta
     3181 ttggaaaacg tattacggta gggattcgta tttctctttt gattgctatt gtcgcaaccc
     3241 tgatcgatct agtgattggg gtaacctatg gcttggtctc aggctttgtt ggtggcaaga
     3301 ctgacatggt gatgcagcgg atcattgaga ttatctcctc tattccaaac cttgttattg
     3361 tgaccatgct tggtcttttg cttggcaatg gtgtgacttc aattattatt tcaattgcga
     3421 ttgtaggctg gacctcaatg gctaggcagg tccgcaacct aaccctgtct tatcgagagc
     3481 gtgatttcgt ccttgcttct cgtgccttgg gagaaagtaa tatcaggatt gcctttaagc
     3541 atgtattgcc aaatatttca gggattatta ttgttcaaat catgatgact gttccgagtg
     3601 ctatcatgta tgagtcagtt ttatctgcga ttaatttagg cgttaagcca ccgacagctt
     3661 cgattggttc attgattact gatgcacaag aaagcctgca atattatcct tatcaggtgc
     3721 tgctgccggc ttttgccttg gtgttaattt cgctagcctt tattttgttg ggtgatggct
     3781 tgcgtgacgc ttttgatcca aaatcaagtg atgaataggg ggaaataaaa tgacgaatga
     3841 aaccatttta agtgtcaaaa acctccatgt tgattttaaa acctacgctg gagatgttaa
     3901 ggcgattcgt gatatcagct ttgagctaaa aaagggagag actcttgcga ttgtgggaga
     3961 atcaggctca gggaaatctg taaccactcg cacgctgatg gggttaaatg ctaagaatgc
     4021 aagtatttca gggaatattt gctttaaggg caagcagctc aatgagctga aggaggagga
     4081 atgggtcaag gtgcgtggca atgaaattgc aatgatcttc caggatccga tgaccagcct
     4141 tgatcctacc atgacaattg gcatgcagat tgcagaggca ataatgattc atcaaagcat
     4201 tcataagaca gaagccttga agcgtgcttt agacctgatg cgtcaggttg gtatcccaaa
     4261 tgctgaggag caccttaagg attacccaca tcagtggtct gggggcatgc ggcaacgggc
     4321 tgttattgcc attgctctag ctgccaatcc tgatattttg attgcagatg agccgacaac
     4381 agctcttgat gttaccattc aggcccagat tttgaagctg atgaaggata ttcagtctca
     4441 gaccgcatca tcgattatct ttattacgca tgaccttggt gttgttgctg gaatggtaga
     4501 tcgcgttgct gtcatgtatg ctggaaagat tgtcgaatat ggaacggttg acgaggtatt
     4561 ttatcatccg cagcaccctt atacctgggg cttgctcaat tcgatgccaa caacagctac
     4621 tgcagcaggt agcttgaggt ctattcccgg aacgccgcca gatttattaa accctccaaa
     4681 gggagatgct tttgctgccc gtaatgagtt tgccctagac attgaccata tcaaagagcc
     4741 tccaatgttc aaggtaagtg acagccacta cgcagcaacc tggttgctag atgagcgtgc
     4801 tcctaaaata acccctccat tcccaatccg caagcgttgg gcaaaatggc aggaaatgga
     4861 agagaggaag gcttaatgac agaagctcgt aaaaaattaa tcgaagtaaa gaatgtttcc
     4921 ttaaccttta acaaggggaa gaaaaacgag gttaaggcta ttgatcgcct tagctttgac
     4981 atttatgagg gggaagtatt tggccttgtt ggggaatcag gctcaggcaa gacgacagtt
     5041 ggtcgagcta ttttgaaact gtatgacatt agtgatggtg agattatctt taacggagaa
     5101 aatgtctccc aattaaaagg gaaaaagctg catagctttc gtaagcatgc acaaatgatc
     5161 ttccaagatc ctcaggctag tttgaacggc cgtatgaaaa ttagagacat tgttgcagag
     5221 ggcttagaca ttcatggctt gacagcctca aaggcagagc gtgaagcaag agtccaggag
     5281 ctgttaaagc ttgttgggct caatcagaac catttgacgc gctacccaca tgaattttcc
     5341 ggtggtcaac gccagcgaat tggcattgcg cgtgccttgg ctgtgaagcc gacctttatt
     5401 atcgcagatg agccgatttc agcgcttgat gtgtcgattc aagcacaggt agtgagtctc
     5461 atgcagcaat tgcaaaaaaa gcgtggcttg acctatctct ttatcgctca cgatttgtct
     5521 atggtcaaat acatttcaga ccgtattggt gtgatgcatt ggggcaaaat gcttgagatt
     5581 gggacatctg atgaggttta caatcacccg attcaccctt atacgaaaag cttgatctcg
     5641 gccattcctg agccggatcc tgaaaaggag cgtaagcgta ttgcagaggt ttatgatcct
     5701 agccaggagc tagatggcca agagcgacaa atgcatgaaa tcactcctgg gcattttgtc
     5761 ttagcgactc aggccgaagc cgagcagtac cgagcagagt gtggccttta agagactagc
     5821 ataacagcaa tttcctaaaa aggctgatgt gatagttttt taggtatgac agaccaaaag
     5881 tcgtatgacc tttgccgatc aaaagcaggt gccatgcgat tttggtggta tggtggagct
     5941 ttgtcagcca acctagactg cacaaaaagc tccttatgat agaatttgta gcatgaggtt
     6001 gcgacacaag tctaccctaa aataaaacaa aataaaacaa ccgaacaggt ctagctttct
     6061 gagatttcaa aagccagacc tgttcggttt ttaatgaatg agactaggtc ataaagtatc
     6121 ttagttaaga ttgtctaaag tgcagctctt tttgctgtgc ttgctgctgt ttttataaaa
     6181 tgactcgtgg gaatcaatca gcctgtagtc aaatgttatc gctctctttt tgagatgtgg
     6241 cttgacaggt ttgctaagct cagcaggcta tttttagtag tatagctaga caaaggccct
     6301 taagctagct cagcacgtca ctctgttaag cttagctaac agcacgtgtt gggcaagtag
     6361 tatgcctcat agccttgtac gtcagtcatt gacgttgacg caacaaaaaa acacgagtct
     6421 ctaagctcgt gtcaaagatc tattggctat caggcgttag aaccatcgga atgataatag
     6481 gctcgcgctc tgtcttttcg taaaggaagg gacgaagcgc attaacgata gcaccattga
     6541 cagactggat actagcgtcc ttatttttca gagcgatacg aatcgcattg aaaagcacgc
     6601 gctgactctc tctgatgagc tcgcctgact cgcgcatgta gataaagccg cggctgagaa
     6661 tatctggtcc ggctaagatc atctgtgtct caaaatcaac agtcgccact gcaaggacaa
     6721 ccccgtcctc tgaaagatca cgacgatcgc gaaggactgc tgtcccaata tctccaatgc
     6781 cattgccatc tacataaatg tcctgagcat tgaaatgacc ggctatacga gcgctatcac
     6841 tggtcaaggc caatacgtca ccattttcca tgataaagat attttcctct ggaatcccaa
     6901 tatcaacagc aagcccagca tgaaccttct gcatacggta ttcaccatgg acaggcataa
     6961 agtattttgg cttaataagg ctaagcatta gcttttgctc ctgctggcca ccatgaccgg
     7021 aggtgtggat attgttgacc tttccatgaa taacgtcaac tccagcctcc tgaatcgtat
     7081 tgattagctt attgacgctg acggtattac caggaattgg acttgatgaa aagatgacag
     7141 tgtctccagg ctgtaagctg acctgtctgt gggtaccatt ggcaatccta gcaagggcgg
     7201 ccatagactc cccttgactg ccggtacaca tgatcaaaat ctcactagcg tggtaatgtt
     7261 taatctcatt aggctcaata aaggttccct ttgggacctt gatgtagcca agctcaatac
     7321 cgttaacaat agccttttcc attgaacgac caaatacagc aatcttacgc cctgtcttaa
     7381 cagcggcttc tgcagcctgc tgcaagcggt agatatttga agcaaaggaa gcaaaaatga
     7441 tacgtccatg aatgccttca ataatgttca tgattgactg gccaacgacc ttttcagaat
     7501 tcgtaaaggt tggtatctcg gcatttgtcg aatcggacaa tagacaaaga accccgtcct
     7561 taccaagagc agccatgcga tgtagatcag ccggatcacc aacaggtgta aagtcaaact
     7621 tgaagtcgcc agtacagatg actttccctt gtggggtgtg gataacaatc ccaagtggct
     7681 ctggaataga gtgagttgtt ttaaagaagg taacgctcat atgcttaaag gtgagctcgg
     7741 tattgtgatt aatctcatag agcacagcat cgcgtaagag accgtgctcc tccagctttc
     7801 ctcggataag agctagagct aaggggcctg catatatagg cacattagct tgctttagta
     7861 aaaaaggaat accgccaata tgatcctcat gaccatgagt aatcacaaga gccttgacgc
     7921 gctccaaatt gtcaacaata taagagtaat cggggataac atagtcaatc cctagcagat
     7981 cgtcctctgg gaatttgata ccggcatcga caatgatgat ttcatcttga tactcaatac
     8041 cgtaggtgtt tttgccgatc tctcccagac caccaatcgc ataaacccca acctcattag
     8101 gccttaaact gatatttgtc atgttaaaac tccgttaatg tgaaaacacc agtttctttt
     8161 tcgtagtcta ggtgcttgtc tgagagcagc tcgatgaatt cgacattgta atcggtgtgc
     8221 tcttcaacca tcttgcgggc tttgatacgc ccctcaagct cacttgcagc gtctatatct
     8281 aggtataggg cctgtgtgtt ttcacgacgc ggactgcgtt cctttgtttc ttggtagaaa
     8341 actttataaa tcattgatga tatcttcctt tcatgatgaa tcgattatcc aaacaataac
     8401 aaataggtca aaacgagaag gcctctgttt tgacgattac ctatcatgtg attattgtgt
     8461 aatagattta aacctgattc tgtgcaatta ctaagattat accatactat cggcttttag
     8521 taaaaagttt cgataaaatt attctcttga ccggtgatga ggctgtggct gtctcctttt
     8581 ccatgacctt tattttatgt tataattgtg gaatagaaat gacttgagaa gggcttagta
     8641 tgaagacact tgcatttgac acatcaaata aggcattatc tgttgctcta ttagacgatg
     8701 gcacattatt ggctgatctt acgattaatg ttaagaagaa tcacagtatt agtctgatgc
     8761 cggctattga ttttttaatg tcctcagctg acctgaagcc aaaggatctt gatcggatcg
     8821 tagtagcaga agggccgggc tcctatactg gcttgcgtgt tgctactgct acagcaaaaa
     8881 tgcttgctta tagcctaagt attgacctcg ttggcgtatc aagcctatat gccctagcgg
     8941 cttctacttg ccgagaaaac cctgatagct tggttgtccc tttgattgat gctagacgac
     9001 gccatgttta tgtgggctat tatcaccatc aaaaagctgt gaaacaggat aagtacgcgt
     9061 cctttgatgc tgttttagca gaactggtct cttgtgacca tgtgattttt gttggagaag
     9121 tggagggctt tgcagaggac attcgatcag ccttgccaga ggccaagata aagccaagtc
     9181 tgccatcggc ttttgaggtt ggtttgctag gcagcagcct ttcagctgac aatgtagcag
     9241 cctttgtccc acaatatttg aagcgggtcg aggcagagga aaactggctc aaaactcatg
     9301 ctgccggtga tgacagccag tatgtcaagc gagtttagcg atgatgtcta tccaagaaaa
     9361 agcagcagct gtctatcagg tgctaaaaga ggtctatggt caatcccctt ggaccttaaa
     9421 gcagatagtg tctgatatgc agcaggagca tgttgattat tttacctttt atcatcagga
     9481 gaccctgcta ggttttttag cgattcaaca gctgccagga gaaatggaaa tcactaatct
     9541 agctgttttg ccaagctatc aggggcaagg gattgcctct tggctcatgg gacagctaga
     9601 tggctttgag ggagtgatat ttcttgaggt tagagcgtca aaccataggg cgcagcagct
     9661 ttaccttaag catggctttg aggtggtagg ccagcgtagc aattattatc atgatccaat
     9721 agaagcagcc ttgatcatga ggcgggaagg aaagaatgac agatagatat attttagcag
     9781 tggagagctc ttgtgatgag acaagtgttg ctatcttaaa aaacgacaac gtcttattga
     9841 ccaatattat tgctagtcag gttgaaagtc acaagcgttt tggtggagtg gttcctgaag
     9901 tggctagtcg tcatcatgtg gaggtgatta cgacttgctt tgatgacgca ctcaaggagg
     9961 cccagcttga ggcttctgac ttgactgcgg ttgcggttac ctatggacca ggtctggtgg
    10021 gggccttgct agttggccta gcagcagcca aggcctttgc ttgggctaat gatttgccct
    10081 tgattccagt caatcatatg gcagggcacc tgatggcggc acgcgagcaa ggagagctgg
    10141 aataccctct tatggctctc ttggtttctg gtgggcatac agagcttgtc tatgtgaccg
    10201 agccaggaga atatcatatt gttggagaaa cacgtgatga cgcagttggt gaggcctatg
    10261 ataaggtagg acgtgtgatg ggcttgccct atcctgctgg tcgtgagatt gatcagctag
    10321 ctcaccaagg gacagatacc tatcattttc ctcgtgccat gatgaaagag gatcatttag
    10381 aattttcttt ttcaggccta aaatcagcct ttatcaacct gcaccataat gcgcagcaaa
    10441 agggtgagga gcttgtgctt gaggatctct gtgcttcctt tcaggctgcg gtgttagata
    10501 tattgttagc aaaaacgaag aaggcactca agcagtatcc atcaaaaatg ctagtcgttg
    10561 caggtggagt ggcagctaat cagggacttc gtgagcgttt agctgaggaa ataactgata
    10621 tagctgttgt gataccacct ctaagattgt gtggagataa tgctggtatg attgcgttgg
    10681 cggcggtggt tgagtacgag aaagggcatg tggcaggctt ggatctaaat gctaagccga
    10741 gtctagcctt tgatagcttt catcagcagt agtattagta tgaggagatt gtcatgtttt
    10801 atttattgct tcccccattg atttgcagtg tggtattttt ggctgtctat attaaggagc
    10861 caagaacgct gtggctagga gctagctttg tgacgaccct aggtgttagt ctcttgtgtg
    10921 ctatgattta cattttttca atcgaagaaa agcttcaggg agttggtatc ctagtgctag
    10981 gtgttattgg gtttcttgcg attgtatggt tgatgtctag tccctttatc ctcttgctct
    11041 ttctaagctt taatggcatt aggctcatca aaagagaggg gctttccttt cggaatttat
    11101 tgctgattgg ctcagcggtg ctattgtttg tacatccttt tatcagcaga ctattgttag
    11161 agagtatcgg tgattcaaag cttttaagga tcatgtatga aacgagtgac ctcttaatcc
    11221 tttacctctt gttaatcgta tcagtctaca ccatctcaag catgctgaat accttttact
    11281 tcagaaaaac caaggaggat tatattattg tgctgggcag cggcttaaat ggagaccagg
    11341 tcaccccctt gctagctagc cgcattaata agggcattca gatttaccag aaaaatcctg
    11401 gcagcaagct gatcatgtct ggtggcaaag gggctgatga gctaatagct gagggtgagg
    11461 cgatgtgtcg ctatgcaatc cagcaaggaa tcaaaagtga agatatatta gttgaaaacc
    11521 aatccagaaa caccagagaa aatattctgt tgtctaagca attaatacca tctggagctt
    11581 ccttttgctt ggtgaccaat cgttaccacc tgtttagagc cttattactg gctaaggagc
    11641 tagccttgcc ttgcaggtgc tatggggcaa aaacaaagct ctactttagt atgaatgcct
    11701 ttatcagaga gattgttggc tatctccaat taaagaaaaa gcagcacctg ctggcaatgc
    11761 tcatcttaac agtaggctat atagccataa gagtggtgat gatctatatg ctgcacattt
    11821 gatgtcattg gcaaaaaagc taaggctagt cacctcgtct tgggctgaaa aagtctctct
    11881 taggtccttt tctcagatga tatgagcaag cagccttttt aaaaaggcta catctaggat
    11941 tttatggagc cttagagctt gttgtgtggt gatgttcaat ggaaccaatc acaattgtta
    12001 cagcaaaaag caggccttta ggaacgtttg ctttgctggt aagtcctttt acttgcagag
    12061 gctggctaca ccagccaaag gctaaggcaa gtgatttagc ttgtgatgat caaggagttt
    12121 taagacgtaa aaaaatagct cggtatcttg gcataccgag ctatcatgat aaattggctt
    12181 ctatgattac taaatcttaa acaaggtgag tcaagcttac cagctagcct tagtgattcc
    12241 tggtagttgg cctttgtgag ctagctcacg aaaattgata cggctgacac caaacttacg
    12301 catgtaagca tggggacggc catcaattct atcacgattt ttcaagcgat ttggatttga
    12361 atcacgtggc aatttgcgca gtgcttcata atcacccttt gctttaagct cgcgacgaag
    12421 gtcagcatac tgttcaatca gttggagctg cttatggtat ttagcaattt ttgacttctt
    12481 tgccattgct ttctccttct taatatttaa taatctcaga gcgttatcag caccctgaat
    12541 ttcctcaacc agtcattaat cagttaagaa aacatagctc tattatacac taatttcaat
    12601 caaatgcaag aaaaatagat aactgattaa ccagttgagg caaaaacagc ctgccagtga
    12661 gtctactgac aagcctagct tagctttgcg agcttcctgc cacccagcca gagcagaggg
    12721 cagctgtaat gttaaagcca cctgtatgag cattaacatc taagacctca ccagcaaagt
    12781 aaagtcccgc gacctttttg ctttctaggg tcttagggtt gatttctttt aagtcaatgc
    12841 cacccttggt tacaaaggat ttggccagag atatttttcc tgtgattgga atcggtaatt
    12901 gcttaatcct gttgacgagc tcctgagtct gtgtgggagt taactgcttt cctttttctg
    12961 gatagccctt tgctaaaaaa tcagcgactc gctcaggcat caaagtcttg agcgcatttt
    13021 taagggcctt ttcccggtgc tgcgctagat agctgagcag ctcagctgcg gaggtttgtg
    13081 gcagcaggtc aagctctgcg atgtcacctc ccttaacaaa ggaggaaagc ctgagagcag
    13141 cggggcctga caacccaaaa tgggtaaaaa gcaaatcgtg agtgatctga tgtttcccac
    13201 agctaagggt cacatcagca agtgaaatcc cctgcagagc cttatgtgga aagtctgtta
    13261 ataaggggct ttccgcagcc tctagctcgg tgacagctat gttaaagtgg cgagcaatat
    13321 catagccaaa gcctgtcgat ccagtagatg ggtaggactt gcctcctgtt gccacgataa
    13381 gcctctcgca gctgaaggtt tgatcaactg atttgaggta aaaaaggtta ttccgctttt
    13441 tgaccgagac aatctcggta ctgatcagca cctgagctcc tagtgacttg attttttgct
    13501 ccagcgcatt gataatcgtc tttgattgat cggtcgtagg aaacatgcgt ccatgatcct
    13561 cttccttgag ggtcacccca ttttccttga aaaaggcaat gatgtcatga ttatcaaatt
    13621 gggaaaagac gctatagaga aagcgcccgt taccgggaat gcccgcgatt agctcatcat
    13681 ggcttccgct attggtgaca ttgcagcgtc ctcctccagt ccctgctagc tttttgccta
    13741 ggcgcttgtt tttgtcaagt aggagtgtct tgtagccata gtagctacta gagatggctg
    13801 ccatcatacc agcaggacca cctccaataa taatcgtgtc gtatagtatc atgtgcttat
    13861 tttagcataa catcaagcga tttaacagta atgtaaacta ggctaaattg acagaattct
    13921 ggtattgtgt tactattttt aataagaata ttcagttaca gtaataaaga ggaaattatg
    13981 gcaatagaaa agacagttag tgaactagct gacattttgg gagtgagccg ccaggctgtc
    14041 aataatcgtg tcaagtcctt accagaggag gaccttgata aaaatgataa aggggtcact
    14101 gtcgttaagc gtagtggctt ggttaagctg gaggaaatct acaagaaaac catttttgat
    14161 gatgagccaa ttagtgaaga gaccaagcag cgtgagctct tagagattct ggttgacgaa
    14221 aaaaacactg aaatcactcg cttatatgag cagctaaagg caaaggatag ccagctggct
    14281 gctaaggacg agcagatgcg tattaaggac gttcagattg ccgagaagga caagcagctg
    14341 gatcagcagc agcagctgac agctaaggct atggcagaca aagagacctt gaagctggag
    14401 cttgaggaag caaaggctga ggctgatcag gtacgactgc aagcagagga gatacagtct
    14461 gaaatgggac ctaaaaaagg ttttttaaat cgtttatttg gtaaataaca gtataccaag
    14521 accctctaag ggtctttttt gaggagagaa gaatgaaaca attagaagca tatattgcct
    14581 ttgatatgga atttaatact gtcaatgagg ttagtcatat cattcagctt tcagcggtca
    14641 aatggcacaa gcatcaggag gttgacagct ttgacagcta tgtttacact gctgttcccc
    14701 tgcaaagctt tatcaatggc ctgacaggca ttacctcaga taagatcgta tcagcaccca
    14761 aggttgatga ggtgcttgat gcctttaagc aatttgtcgg tgacacgcct ttgataggct
    14821 ataatgcaca aaagtctgat ttgcctattt tagcagcaaa tggcttggat ctgtcagcgc
    14881 aatatgcagt cgatgtcttt gatgaagcct atgagagacg aagcagcgac ctaaacggga
    14941 ttgctaatct tcgcctgcaa acagttgctg attttttagg gataaaagga agaggacata
    15001 atagcttaga ggacgctcgt atgacagcgc gtgtctatga agcgtttgtg gaatttgacg
    15061 acaataagtc ttacctaaac aaacaaaaag aagcgattgc agataacccc tttgcagctc
    15121 tgggagggct ttttgactag cagcgctagt catttctctg aaaaagaaaa atgacctaag
    15181 gtcagggctt gcttgtgacc ttgggtcata ttctataatg aggacagaaa ggaggtgaag
    15241 gacatgtctg atatttactc aactggtgag ctagcaaaag cagcaggtgt cactgtcagg
    15301 acagtgcaat attacgataa gcgtgggatt ttgttgcctt cccagcttac tgaaggtgga
    15361 cggcggattt acaccgagtc agatttggag cgattgaaaa tcatttgctt cttacgggac
    15421 ctagattttt ccattgagca gattaagcgc gtgctagcag aagacaatgt tatggcggtg
    15481 cttgacctct tgctggtgga tcatatccaa cagctggaac aagacttaag gacaaaaaag
    15541 catcagcttg acacagctgt caagcttttg tcaggtattc gctgctcatc tagtcactct
    15601 atcaaaaacc tatcagacat gtcacttacc atgaacaatc aaaaagcttg gcgtcgtttg
    15661 cagttgaaaa tgtttagtaa tattgcccta gcaatattgg ttcatgtgat gttagtgtta
    15721 ctaactagct attttcatct atcttggttg gtatggatag aggctccact atggataatc
    15781 ttttttactt tattgatcgt ttattttcgt aaacaatttg agtacctatg tccaaattgt
    15841 catactattt ttgaaccaga ctttaaagag tttgccttgg caggtcacac accaaggacc
    15901 cgcaggctga cctgtcctca ttgccatcaa aaatcttact gccttgaatt ggccaaggaa
    15961 aaataatgga aaatctccgc tggataccca gtggagattt cttgctatta gaatggtagc
    16021 ttgccagcaa aggctcctag agttttctta gtcgcctcat caatttgagc gagggctgca
    16081 ttgatggcct gagcagtcat atcctgaagt gtctctatat cctctgggtc aacgactgct
    16141 tccttgaaat caatgctaac caattgctta tcacctgtaa aggttgcagt gaccagctcc
    16201 tgagctgact ttcctgtaaa ttgcatagct gctaggtcag cctgcttttg ttccatttgc
    16261 ttttgaagct tttgcgcttg cttcatcatg ttttgcatgt tcatcataag ttccaattct
    16321 cctaagtttt gatacttaac tattataaca tatcagacaa gacttcaaac atgtgatctt
    16381 ttaaagttaa tgaaaaggcc ctgctagcct gcaatgcttt gatgtgctag cgactaacga
    16441 acaggtcgtt tcctttaaat agagttttct tgttgagctt tatagctggt gcttgttttt
    16501 gtgatgagct tgtgtgaggc tgtcgttagt gttgttttag gtggtttgac atcaggagcg
    16561 attaaaaaag ttatcagttt acatttttat aataataact taagaattaa tttaacttta
    16621 gattaatctt actttatatt tgattgctat acttagtcca taacataaat aaccaaaaag
    16681 aaagaggtaa tcgttatgac aacaatgact acaacaaaac aatcaaagac aactctagca
    16741 gctcgttatt tgaagcttgg tcttacttca gcaatgtttg ctggaggagc ctttctagct
    16801 ctaggctcag caccggctgt ctctgcttct acccatgctg gtaatgatca gccagcgact
    16861 caacgcttaa ctgatcagga gatctacgaa cgtgctcaaa agctagactt gccagactat
    16921 gtgagaggct caatctacgg tattctcaac caaaactcaa gtgttactta tccaaaggat
    16981 atagcaggtc tagagcagtc agaagctcca caaccccctg cagctccaca gctcactgac
    17041 caagatgctc aaaagctgga cttgccagac tatgtgagag gctcaatcta cggtattctc
    17101 aaccaaaatt caagtgttac ttatccaaag gatatagccg gtttagagca gtcagaggct
    17161 ccacaacccc ctgcagctcc acagctcact gaccaagatg ctcaacagct agacttgcca
    17221 gactatgtga gaggctcaat ctacggtatt ctcaatcaaa actcaagcat tacttatccg
    17281 cgcgattatt aagcatctaa gatgattaag gtgcacaatc gacgattaaa atgattgatg
    17341 agttaatgag attagaatta tttggctaag ttaagaatta gtgttatact tgagagagtg
    17401 tagcactaat tttttaatca aggaggaagc atgacctaca agatattatt ggtggatgat
    17461 gaattggaaa ttattgatat taacgaacgt tatttgcaac aggcagggta tcgtgttacc
    17521 actgcaagcg atggtagtca agccttggag ctttttcata aggatcagta cgatttgatt
    17581 atcagtgatg ttatgatgcc caatatggat ggctatgatt ttattgggga ggttttactg
    17641 gaaaagccag atcagccctt tctctttatc actgcaaaaa catctgagcc tgacaagatt
    17701 tattccttga gcttgggagc agatgatttt atttccaagc cctttagtcc acgtgaatta
    17761 gtcttacggg tcaaaaatat tttgaatcgg atttatggta aggctaacca agctgactcc
    17821 ttagttattg gggatttggt catggatcac agcactcgaa gggttacagt ggcaaatcaa
    17881 gatctgaatc tgaccaacaa ggcttttgat ttgttgtgga ttttggccaa tcatttgaat
    17941 catgtctttt caaaaacaga gctttatgag cgt
//
LOCUS       DARYXW010000041        17703 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.041, whole genome shotgun sequence.
ACCESSION   DARYXW010000041 DARYXW010000000
VERSION     DARYXW010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17703)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17703)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17703
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.041"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(<1..916)
                     /locus_tag="TV191_001122"
     CDS             complement(<1..916)
                     /locus_tag="TV191_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB N-terminal domain-containing protein"
                     /protein_id="HEL1507644.1"
                     /translation="MSKKLLKREITDAVDFLLDDGNALEQGNIQNIELDLLENYHNHP
                     FTLYTGKRLDDMVESIKENGVLNPIIVLKKDNNYEILSGHNRVNAARITKIKSIPCIV
                     KENLTDKEAYTYVIETNLIQRSFSDLLPTEKALVLKMRYEKIASQGKRNDLQKEINNL
                     DQGIIEKESKEEDKIDSRKTLGKEYNLSGASIARYLRLNELSKSWKKDVDEDKIGLTM
                     AVDLSYLSKEIQEYLYQKCEELELSLKPSDAKALHLMNRQEDLNQEMVITYLLNLKKT
                     KVKKYQNIKLSQSVYKKFFHDERKEDVEE"
     gene            complement(909..1685)
                     /locus_tag="TV191_001123"
     CDS             complement(909..1685)
                     /locus_tag="TV191_001123"
                     /inference="COORDINATES: protein motif:HMM:NF022077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HEL1507645.1"
                     /translation="MAEVITIANRKGGVGKTTTTLNLAYSLKELGKKVLVIDLDPQAN
                     LTRCFDMGNTENIKTIGHLLMVELEEEESYLVEGYTKSYDEIDIIPSSIFLSAVETQM
                     RAETGSERILSEIIRRVKENYDYILIDTSPSLSVLTINALCASDSVLIVADTQLFAVV
                     GINELLKTVQKIKKRVNPKLKVQGILLTMCENRTNLSKTLMEQVEEMFQKKIKVFQTK
                     IPKTVKVGEAIYSGQSIKKYAKGSSVDIAYDNLAKEICYE"
     gene            complement(1837..3000)
                     /locus_tag="TV191_001124"
                     /pseudo
     CDS             complement(1837..3000)
                     /locus_tag="TV191_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677880.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(3002..4723)
                     /locus_tag="TV191_001125"
     CDS             complement(3002..4723)
                     /locus_tag="TV191_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1507646.1"
                     /translation="MLTLIVQHIKQKKWIYILIAMTLVIYDASLVIPTRVIQDLVDLM
                     SRHQLSSGALVRHVIILLATAVVSYGVAYLWHLHLFQEAVHFKFDIQQRAFRKLVFMR
                     TPFYEKFRSGDMITRFSTDVEALMDLIGYGLMIILYAGGMIAFIIPTMFLISWKMTLI
                     GIVPILLMMVMIYGVTKKQEHLVEEAREAISSLSDEVLETVEGIRVMRAYSKKDYLAL
                     HFAQKTQNLADKWNQVAKYRALYFPLYSVMIAISTVIILMVGLQLIASSEVTLGQVIA
                     LQLYLVSLVEPFGMLSDFILVYQTGKTSFGKINELIETSDDMEPDGQLELESFDQIAF
                     IDYSFTYANSSRPSLEKINLTLKKGQTLGIVGKTGSGKTTLVRQFLRQYPLGQGQLMI
                     NHRSVLDYKRQSLERQIGYVPQEHILFSKTVAQNIAMGKKAATTEEILEAIETAAFTR
                     DVQGMAKGLDTEIGERGLSISGGQKQRISIARAFLSQPDLLILDDSLSAVDARTETDI
                     IRHIQDERKGKTTLIVSHRLSAIQHADWVIVLDQGQIVEEGQPQQLLAQKGWYYEQYQ
                     RQQAQEV"
     gene            5172..7178
                     /locus_tag="TV191_001126"
     CDS             5172..7178
                     /locus_tag="TV191_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase C-terminal domain-containing
                     protein"
                     /protein_id="HEL1507647.1"
                     /translation="MKKHFVLKSSVLGVFAGVSMLVTGVQADQVDVQFLGVNDFHGAL
                     DTTGSAYMPEGKVSNAGTAAQLAAYLDDAEADFKQTSPDGTSIRVQPGDMVGASPANS
                     GLLQDEPTVKVFNQMGFEYGTLGNHEFDEGLAEFNRIMTGTAPAEDSAINDITKQYEH
                     EASNQTLVIANVVDKETNTIPFGWKPYAVKEVPVNDKSVKVGFIGVVTTEIPNLVLKQ
                     NYEQYDYLDSAETIVKYAKELQEQQVNAIVVLAHIPATSDNGVVHDEMAAVMEKVNQL
                     YPEHSVDIVFAGHNHQYTNGTIGTTRVVQAVSQGKAYADVRGTLDTDLNDFVATPEAK
                     VIAVAPGIKTGNADIQAIVDQANDIVKTVTELKIGTAATSSTISKTENEDKESPVGNL
                     ITTAQLTIGRKTFPHVDFAMTNNGGIRADLVVKEDQTITWGAAQAVQPFGNILQVVQM
                     TGQQIYDVLNQQYDEDQKYFLQMSGLKYTYTANEANDPSTPFKVVKAYKDNGEEIDPA
                     AQYTLIINDFLYGGGDGFSVFKDAKLLGAINPDTEVFIEYIKDLEAAGKTVSAGINGV
                     KTYVTASLEGSTQSDHTGKHEIINRVFKNREGKVLATELVSDLFTPAQNANPATSIKP
                     LAAKKQANAALPATGTSQHSAAAMTILGLLTLTGTSLFKKKEGQ"
     gene            complement(7369..7779)
                     /locus_tag="TV191_001127"
     CDS             complement(7369..7779)
                     /locus_tag="TV191_001127"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEL1507648.1"
                     /translation="MIKKIVKDTFFLQQKAQPATKKDLWIGQDLQDTLAYYRDSCLGL
                     AANMIGENKRVIIISMGFVDLVMFNPVLIAKREAFEAEESCLSLIGQRKTKRYQEIKV
                     DYLDAHWHKKSLRLTGLPAQICQHELDHLEGILI"
     gene            complement(7911..9260)
                     /gene="gdhA"
                     /locus_tag="TV191_001128"
     CDS             complement(7911..9260)
                     /gene="gdhA"
                     /locus_tag="TV191_001128"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEL1507649.1"
                     /translation="MVSAKDYVASVFDKVKRDNPHETEFLQAVKEVFDSLIPVFEKYP
                     NYIEENLLERLVEPERVISFRVPWVDDQGRVQVNRGYRVQFSSAIGPYKGGLRFHPSV
                     NQSIVKFLGFEQIFKNALTGQPIGGGKGGSNFDPKGKSDLEIMRFTQSFMTELQRHIG
                     PDLDVPAGDIGVGAREIGYLFGQYKRLNGFKNGVLTGKGLAYGGSLARTEATGYGVVY
                     FAQQMLAAKGQDLAGKTAIVSGSGNVAIYATEKLQALGVKVLAVSDSSGYVYDDKGID
                     LETLKQIKEVKRERIKTYLESHPAAVFTPAGEGSIWTIKADLAFPCATQNELQEADAK
                     ALIEHGVKAVVEGANMPSTLEAIEQFQQAGVLFGPAKAANAGGVAVSALEMAQNSGRT
                     AWTFEEVDHRLYDIMKAIYQKAAAAAKECGQEGNLVVGANIAGFLKVAQAMSAQGIV"
     gene            complement(9401..11177)
                     /locus_tag="TV191_001129"
                     /pseudo
     CDS             complement(9401..11177)
                     /locus_tag="TV191_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738789.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(11177..12922)
                     /locus_tag="TV191_001130"
     CDS             complement(11177..12922)
                     /locus_tag="TV191_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1507650.1"
                     /translation="MALIWSYLKTRPKWICFDIVGGLLFVLVNLGLPTILARMIDQGV
                     MQQDQRALYFWALMMFIIVLLGVIGRVILSYASGKLTTNMIKDLRNDMYSCLQDYSHS
                     EYEKIGIASLVTRITNDAFVLMQFAEMSLRLGVVTPLMMIFSVVMIFLTSPSLAWIVA
                     VAMPFLVIVVLYVAIKTRPLSEKQQESLDRINQLVRENLTGLRVIRAFAREDFQEERF
                     NKRNDHYSGISKRLFTLTGLTEPLFVQIIIAMIVGIVWFALDPLARGQFKIGDLVAFI
                     EYSFHALFSFLMFANLFTMYPKTAVSSKRIKEVLDMPISIPKNEDGITAFTTRGYLEF
                     DNVTFAYPGETESPVLHNISFKTRPGETIAFIGSTGSGKSSLVNLIPRFYDVTLGRIL
                     VDGIDVRDYQLKALRSKIGFIPQKALLFTGTIEENLKYGKSDASHSELEQATEVSQAK
                     DFITSREKSYQTHLAEAGSNLSGGQKQRLSIARAVVKQPDIYIFDDSFSALDYKTDAE
                     LRRRLKEVTQDATVLIVAQRVGTIMDADQIIVLDQGEIVGRGTHEELLTSNAIYREIA
                     NSQLNKEDMTKEEGD"
     gene            complement(13027..14894)
                     /locus_tag="TV191_001131"
                     /pseudo
     CDS             complement(13027..14894)
                     /locus_tag="TV191_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854406.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
     gene            complement(14887..16098)
                     /locus_tag="TV191_001132"
     CDS             complement(14887..16098)
                     /locus_tag="TV191_001132"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEL1507651.1"
                     /translation="MTLMTMPSEFQKALPIVKKIKQAGFEAYFVGGSVRDSLLNRPIH
                     DVDIAASCYPEETKAIFLRTIDVGIEHGTVLVLENGSEYEITTFRTEDVYVDYRRPSQ
                     VSFVRSLEEDLKRRDFTVNALALDEDGQVIDIFNGLEDLKHKLLRAVGRPQERFEEDA
                     LRIMRGFRFAASLDFDIEAETFEAMKSHAPLLEKISIERSFIELDKLLMAPKWRKGIL
                     AMVACQAFNYLPGLVGKEEALQKYLKTLAADYVFQDNHQAWAYLLVMLELDQPKAFLK
                     AWKTSNDFQRRVTMMASLYQIRQERQLEKWDIYSFGKDLALLVDDLRQAQGLVSEAKR
                     VESLYQELTIHDKHDIVVNGSYLIRELGMKPGPQLGMLLNQIEQAIVEGRLVNQREHI
                     EAFVRRELLNE"
     gene            complement(16198..17046)
                     /locus_tag="TV191_001133"
     CDS             complement(16198..17046)
                     /locus_tag="TV191_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL1507652.1"
                     /translation="MKLAIITDNTAHLPEQLAEHADIFVLDIPVIIDGQSYVEGQNLT
                     IEAFYQSMRESQELPKTSQPSLSELDDLLGRLSTEHYTHVIGLFLASGISGFWQNIQF
                     LIEEHPELTIAFPDSKITSASLGSMVRNALEWSQQGLSFAEIMDKLEEQIAGTTAFIM
                     VDDLNHLVKGGRLSNGSALLGNLLSIKPILRFDSEGKIVVYEKVRTEKKAMKRLVDIL
                     KELTASGQYEVSIIHARAQDKADILKQLLLDNGYTCPVEEVHFGAVIAAHLGEGAVAF
                     GITPLV"
     gene            complement(17046..17426)
                     /locus_tag="TV191_001134"
     CDS             complement(17046..17426)
                     /locus_tag="TV191_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEL1507653.1"
                     /translation="MQLVREKEFVNQYHYDARNLEWEKENGTPETNFEVTFQLINKDV
                     ENKETAIVSVLQFVIVKEEFVISGVISQMVRILGRLVDKPSEFTQEEVESLAAPLLDM
                     VKRLTYEVTEIALDRPGINLEFKS"
     gene            complement(17631..>17703)
                     /locus_tag="TV191_001135"
     CDS             complement(17631..>17703)
                     /locus_tag="TV191_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEL1507654.1"
                     /translation="NNKRIKTKLKGLSPVQYRTKSFQ"
BASE COUNT         5198 a         4136 c         3177 g         5192 t
ORIGIN      
        1 tttcttctac atcttctttc ctttcatcat gaaaaaactt tttatagaca ctctgagata
       61 gtttgatatt ctgatacttt tttaccttcg tttttttcaa gttcagcaag tatgttataa
      121 ccatctcttg attcagatct tcttgtctgt tcatcagatg gagtgctttg gcatcgcttg
      181 gttttaaact tagttccaat tcttcgcact tctgatacag atattcctgt atttctttgg
      241 aaagatagga taaatctact gccatcgtca aacctatttt atcttcatcc acatcttttt
      301 tccaagactt agataattca tttaatctta ggtaccttgc aatagatgcc cctgaaagat
      361 tatattcttt tccaagtgtt tttctgctgt ctattttatc ttcctcttta ctttcctttt
      421 ctataattcc ctgatctaaa ttgtttatct ccttttgcaa atcatttctc ttgccctgac
      481 ttgctatttt ttcatatctc attttaagaa caagggcttt ttccgtcggc agtaaatcgg
      541 agaaagaacg ctgtataagg tttgtttcaa ttacataggt ataggcttct ttatccgtta
      601 gattttcttt aacaatacaa ggaatacttt ttatttttgt aattcttgct gcatttactc
      661 tattgtgtcc ggaaagtatt tcatagttgt tatctttttt caagacgata attggattaa
      721 gaactccgtt ttccttaatg ctctctacca tatcgtctaa tctcttacct gtatataaag
      781 taaacggatg attatgataa ttttcaagca aatcaagttc tatattctgt atatttcctt
      841 gttccaaggc atttccatca tcaagcaaaa aatctacggc atcggtgatt tctctcttta
      901 gaagtttttt actcatagca gatctccttt gccagattgt cataggcaat gtctacacta
      961 ctgccttttg catatttttt tatgctttgc ccgctataga tggcttcccc aactttaact
     1021 gttttcggaa ttttggtttg aaagaccttg attttctttt ggaacatttc ttctacttgc
     1081 tccatcagtg ttttggacag attggttcta ttctcacaca tggttagtaa aatcccctgc
     1141 actttcagtt tcggattcac tctctttttt attttttgaa cagtttttaa aagttcattg
     1201 attccaacaa ctgcgaacag ctgtgtatcc gctactataa ggacactgtc tgaggcacaa
     1261 agagcattta tagtcaaaac actaagtgat ggtgatgtat ctatgagaat atagtcataa
     1321 ttctctttta ccctcctaat aatttccgat aatatacgtt cacttcctgt ttctgctctc
     1381 atttgtgttt caacggcgga taagaaaatg cttgagggga taatatctat ctcatcataa
     1441 gatttggtat agccctctac caaatagctt tcttcttcct ccagttctac cattaacaaa
     1501 tgccctatgg tttttatatt ttctgtattt cccatatcaa aacatcttgt aagattagct
     1561 tgtggatcaa ggtcaatgac taatactttt ttccccagtt cttttagtga ataggcaagg
     1621 tttagagttg tagttgtttt tccaactccg ccttttcgat tggctatggt tatcacttct
     1681 gccataaagt ccctccttct tctctataca gagatttcat tttatgctat acttttatat
     1741 aattttagat ataaaaaaag atgatagcct caatccatca tcaagtttaa aagttttgcg
     1801 gaagccttta accattgatt ttacttggat ttattgtact atcatcatta tagcattgtc
     1861 cccagagcca gtatgcccta ctagggcaac cgtctcccct ttatcagcat gaatggtaat
     1921 atcagataaa actgtcttgc cattttcgta agcaaaatac accttggtaa aatccacagt
     1981 accatctgtt agctcaattg ctcgtgcttt atccggctct gtctgcgcct caagcagctt
     2041 cattaggcgc gttcctgtcg ctgttgagcg ctgaatatta ggtagctgcc taaccagcat
     2101 acttaataaa tcaaacaagc gcagcaaata attgacgtaa ataaagagct taccaactgt
     2161 gatgcctgat ctcccctgca agaactggta accaataaca gccaaaatag cggcaatcat
     2221 gccatacttt accaattccg tcagggtcca tgaagcaact gactctgcaa aaataatcct
     2281 atcatcagct gttttcatct ggtggatctg ctcttcaaat tcctctaaga tcgtatcctc
     2341 ttgatgataa agctgaataa tagaaacacc attcatggtt tcgttgactt gtgtgttgac
     2401 agcgctccta gcctgataaa aatccttcat tggctggtca gtcaagcttt tatacagcca
     2461 ttgcatgcca taaaagagtg gcataataag cagcaacagc aagcctgact tcacatcaag
     2521 gtaaatcatc accacataaa taaaaataat ttgtgaaaga ctgacaataa tttgagacaa
     2581 aaggttatca taaaattgat tcttcagggt ttcagtatca ttaacaatcc tagttgcaat
     2641 ctttcctgca ggctgatgat caaaataagc tatcggcagc ctctgcatga catcaaaggc
     2701 tcgattacga agattagcaa cgatcctatt agaggaataa accagcattc gataagagat
     2761 ataacgcaaa actgctgtta tcacaattaa cagcaaatac agcaggagca agcgctgaaa
     2821 gccttcaatc ggtacctctt ttcctctagc tatcggagtc aagtaatgat caatcgtttg
     2881 ttgcaacaat aagggagcca tctgacctcc agctgttgcc actagcaaaa agcctattgc
     2941 cagggaaaaa gccaaggtca cagctttaat ttcttttatt aattttataa atagggtcat
     3001 cttaaacctc ctgagcctgc tgacgctggt actgttcata ataccagccc ttctgagcta
     3061 aaagttgttg gggctgacct tcctctacta tctgcccctg atccagaaca ataacccaat
     3121 cggcatgctg aatcgcagac aagcgatggc taacaataag tgttgtcttt ccctttcttt
     3181 cgtcttgaat gtgtcgaata atatcagtct ctgttctagc atcaactgcc gacagggaat
     3241 catctaaaat cagcaaatct ggctgggaca aaaaggctct ggcaatcgaa atacgctgct
     3301 tttgacctcc tgaaatagac agaccacgct ctccaatctc agtatccaag ccctttgcca
     3361 ttccttgaac atcacgcgta aaggccgcag tttcaatcgc ctccaagatt tcctcagttg
     3421 tagctgcctt tttccccatc gcaatgtttt gagcaaccgt ttttgaaaac aggatatgct
     3481 cctgtggcac atagccaatt tgacgctcaa gtgattgacg cttataatcc aagacactac
     3541 gatgattaat catcagctgc ccctgcccaa gagggtattg tctcaaaaac tgcctgacaa
     3601 gggttgtttt accagagcct gttttaccaa caatccctaa ggtttgtccc tttttcaggg
     3661 ttaaattgat cttttctaag ctaggcctag aactattggc ataggtaaag ctatagtcta
     3721 taaaagcaat ctgatcaaag ctctctaact caagctggcc atcaggctcc atatcatcac
     3781 ttgtttcgat gagttcatta atcttaccaa aagaggtctt tcctgtctga taaaccaaaa
     3841 taaagtctga cagcatgcca aagggctcca ccaaagacac cagataaagc tgcagcgcaa
     3901 tgacttgacc aagtgttacc tctgagcttg ctatgagctg taggcctacc attaaaatga
     3961 ttactgtact aatggcaatc atgacgctgt aaagaggaaa gtacaaggca cgatacttgg
     4021 ccacctgatt ccatttatct gccaaattct gagtcttttg agcaaaatga agtgccaaat
     4081 aatctttttt actgtaagca cgcatcactc taatgccctc aacggtttct agtacctcat
     4141 cactaaggct tgaaatcgcc tcacgcgcct cttcaaccaa atgctcttgc tttttcgtca
     4201 caccatagat catcaccatc ataagcaaaa tcggtactat tcctatcaag gtcattttcc
     4261 aagaaatcaa aaacatggtc ggaataataa aagcaatcat accaccagca tataggataa
     4321 tcatcaagcc atagccgata aggtccataa gtgcttcgac atctgttgaa aaacgcgtga
     4381 tcatgtcacc tgagcgaaat ttctcataaa aaggcgttct cataaaaaca agctttcgaa
     4441 aggcacgctg ctgaatatca aacttaaaat gaactgcctc ctgaaataaa tgaagatgcc
     4501 acaaataagc aaccccataa gacactactg ccgtagccaa aagaatgata acatgcctca
     4561 ccaatgcccc tgagcttagc tgatgccttg acatcaaatc aaccaagtct tgaataaccc
     4621 ttgttggtat cacaagtgag gcatcatata tcactaaagt cattgcaata aggatataaa
     4681 tccatttctt ttgcttaata tgttgaacaa ttaaggtcag catcatatcc tccatttctg
     4741 aactaaccta tttcaagctg tcttaaaata ggatttttgc acacaaaaag cccgcaataa
     4801 gatatccttc ctaccgcggg ctctactatt tctatttagt gaaactaaaa gaaactaact
     4861 gttttggtta gaaaggagac tatcgtaata atggttaaat agttgaatga aacggatcat
     4921 tattaatttc tcctttcttt taatctgcct aacatcttat catagaatac tgggcttgta
     4981 aagccttttt tggatagttc ttctattttt ttacaaaaaa cgcttccaat gtttgcattt
     5041 taaacgtttt cagtgattag caaacgctat cgttgaattt ttgttagctt ttttattaat
     5101 ttttgttgaa ttctcattta aataatagta cacttaactt gtgacaatac tttaaacttt
     5161 taggagcgtt tatgaaaaag cattttgttt taaaaagtag tgttcttggt gtctttgccg
     5221 gagtttctat gctagtaacc ggcgtgcagg ccgatcaggt agacgtgcaa tttcttggtg
     5281 tcaatgactt tcatggtgcc ttagacacaa ccggctctgc ctacatgcca gaaggaaagg
     5341 tatctaacgc tggtaccgca gcacaattag ctgcttatct ggacgatgca gaggctgact
     5401 ttaagcaaac aagcccagat gggacaagca ttcgtgttca accaggagat atggtcggag
     5461 ctagtcctgc taattctgga ctattacagg acgagccaac ggttaaggta ttcaaccaga
     5521 tgggctttga atacggaacc cttgggaatc acgaattcga tgagggctta gctgaattca
     5581 accgtatcat gacaggcact gcacctgctg aagactcagc tatcaacgac attactaagc
     5641 aatacgagca tgaagcttca aatcaaaccc ttgtcattgc aaatgtcgtt gacaaggaga
     5701 ccaacacgat tccttttggc tggaagcctt atgctgtcaa agaagtccca gttaatgata
     5761 agtcagtcaa ggtgggcttt atcggtgttg tgacaacaga aattccaaac cttgtcctaa
     5821 aacaaaatta tgaacaatat gattacctag actctgcaga aaccatcgtt aaatatgcta
     5881 aagagctcca agagcagcag gtcaatgcga ttgttgtcct agctcatatc ccagcaacaa
     5941 gtgataacgg ggtagttcat gatgagatgg cagcagttat ggaaaaggtt aaccagcttt
     6001 atcctgagca tagtgtggat attgtctttg ctggtcacaa ccaccaatac accaacggta
     6061 ccattggcac aacacgtgtc gttcaggctg tttcacaggg gaaagcctat gcagatgttc
     6121 gtggaacact agacactgac ctcaatgatt ttgtagccac tcctgaagca aaggtcattg
     6181 ccgttgctcc tggcataaaa acaggcaatg ccgacattca agccattgtt gatcaagcca
     6241 atgacattgt caaaaccgtt accgagctaa agatcggtac agcagctacc tcttcaacga
     6301 tttctaaaac agaaaacgaa gacaaggaat ctcctgttgg caatttgata acaactgccc
     6361 aattaaccat tggtagaaaa accttccctc atgttgattt tgccatgaca aataatggcg
     6421 gtattcgcgc tgacttggtg gtcaaagagg atcaaaccat tacctgggga gctgcacagg
     6481 ctgttcaacc atttggcaat attcttcagg tcgttcaaat gactggccaa caaatctatg
     6541 atgtcttgaa ccaacaatac gatgaagacc aaaaatactt ccttcaaatg tctggactca
     6601 aatacactta tacagctaat gaggctaacg atccttcaac accgtttaag gtagtaaagg
     6661 cttataaaga taatggtgaa gaaattgatc cagcagctca atacacccta atcatcaacg
     6721 acttcctata tggcggtggt gatggcttct ccgtctttaa ggacgctaag ctactaggag
     6781 ccattaatcc tgatactgag gtctttatcg aatacatcaa ggaccttgaa gcagctggaa
     6841 agactgtaag tgctggtatt aacggtgtga aaacctatgt cactgccagt cttgaaggct
     6901 ctactcaaag tgatcatacc ggcaagcacg agatcatcaa ccgcgtcttt aagaatcgtg
     6961 agggcaaggt gcttgctact gagcttgtct ctgacctatt tacgcctgct caaaatgcta
     7021 atcctgccac aagcatcaag cctctagcag ctaaaaagca agctaatgct gccttaccag
     7081 caacaggaac aagccagcat tctgctgctg ccatgacaat cctaggacta ctaaccttaa
     7141 ctggtactag ccttttcaag aaaaaggaag gccaataaaa tcgtcctagc cataacagca
     7201 ataaccgact gtatcttaag catacagccg gttttctgat ttatgtgacg tttatttgtt
     7261 tcgcacctgt tgagcaagac aaataaacca cccatctatg gactgccctc attcgttaga
     7321 ttttctgtct aacttttggg gtgcagttca ctaacgggtg gtcatgattt aaatcaatat
     7381 gccctccaga tgatccagct catgctggca gatttgtgca ggcaggcctg tcaatctcag
     7441 ggatttcttg tgccaatgtg catcaaggta atcaaccttg atctcctgat aacgctttgt
     7501 cttacgttgg ccgattagtg ataggcagga ttcctctgcc tcaaacgctt cacgcttagc
     7561 aattaataca ggattaaaca tcaccaaatc cacaaagccc atgctaataa taataaccct
     7621 cttgttttcc cctatcatat tagcagccag ccccaggcag ctatcacgat aataagctaa
     7681 ggtatcctgc aggtcttgac caatccaaag gtcctttttc gttgctggct gtgctttttg
     7741 ctgcaagaaa aaggtgtcct tcacgatttt tttgatcatc agcttctcct tgattcattg
     7801 ctctaatcgg catgcattgt ctagatgacc gatcgtatat cttaacgtca ttgagctaag
     7861 attaatgtgc taaccctact gatatattca gcatatacca gccacagctc ttaaacgatt
     7921 ccctgtgctg acatggcctg agcaactttg agaaagcctg caatattagc tcccaccact
     7981 aggttgcctt cttgaccaca ttccttggcg gcagcggctg ctttttgata aatagccttc
     8041 atgatgtcat acaatcgatg atccacctct tcaaaggtcc atgcggtacg tccgctattt
     8101 tgtgccattt ccagcgcaga aactgctaca ccgccagcat ttgctgcttt agcaggtcca
     8161 aaaagaaccc cagcctgctg aaattgctca atagcctcta aggttgaggg catgttagcc
     8221 ccttcgacaa cagctttaac cccatgctca atcaaggctt tagcatctgc ctcttgtagc
     8281 tcattttgag tcgcacatgg aaaggcaagg tctgccttaa tagtccagat ggatccctca
     8341 ccagccggtg taaacacagc agccgggtga ctctctagat aggtcttgat acgctcacgc
     8401 ttcacttcct tgatttgctt tagggtctca agatcaatgc ccttatcatc ataaacgtaa
     8461 ccagaggaat ccgacactgc taatacctta acacctaagg cctgcaattt ttccgttgcg
     8521 taaatggcaa catttcctga tccagataca atagctgttt taccagccaa gtcctgcccc
     8581 ttagccgcca gcatttgctg agcaaaataa accacaccat agcctgtggc ctctgtgcga
     8641 gccaaagagc caccataagc taagcctttt cctgtcaaca caccattctt aaagccatta
     8701 agacgcttat attgcccaaa taaatagcca atttcgcgag cccctacacc aatatcacca
     8761 gcaggaacat caaggtcagg tccaatatgc ctttgcagct ctgtcataaa gctttgtgtg
     8821 aagcgcatga tttctaggtc tgatttgcct ttaggatcaa aatttgatcc tccttttcct
     8881 cctccaatag gctgaccagt cagagcattt ttgaaaatct gctcaaagcc aagaaattta
     8941 actatagact ggttaacaga agggtgaaag cgaagccctc ccttatatgg accgatagct
     9001 gatgaaaatt gcacgcggta gccacgatta acttggaccc tgccctggtc atcaacccaa
     9061 ggcaccctaa aggaaatcac acgctcaggc tcaaccaagc gctctaatag attttcctca
     9121 atataattag ggtatttttc aaaaacagga atcaaggaat caaatacctc cttgaccgcc
     9181 tgaagaaatt cagtctcatg cggattatcc cttttgacct tatcaaaaac actggctaca
     9241 tagtcttttg ctgataccat tatatatcct ctcgcttctt cattctattt taagtatagt
     9301 caatattata aattttctga attttgatgt caagctttta ctatgatcta aagcaaatta
     9361 aaagagcctt ggaacgattc attccaagac cctaagcttt ttaagactga ctggtcttaa
     9421 attggctatg ataaagctca taatagaagc ccttagcagc taataggctg tcatgattcc
     9481 cctgctcgat aatctgacca tcttttagaa ctaaaatctt atccgcctct tgaatggttg
     9541 ataagcggtg agcaataaca aagctagtcc tgccaaccat taatcgcttc atcgcctttt
     9601 gaatcaaaag ctctaaacgt gtatcaacag acgaggtggc ctcatctagg attagcagct
     9661 ttggatctgc taagagagct cgagcaatgg tcagcagctg cttttgcccc agggaaatat
     9721 tgctagattc ctgattcatc accatatgat agccacctgg caatgtccta atgaaatgat
     9781 caacattggc agccttagca gcctcaatta tttgttcatc agtcgcctct aaatgaccaa
     9841 agcgcaagtt ttcctgaatg ctgccctcaa agagccaagc gtcctgcagc accataccaa
     9901 actgacgcct ataggcttga cgtgacaact gacgaatgtc ctgaccatca actgtgatag
     9961 agccctcatt cacatcataa aaccgcatta ataaattaat cagggtggtc ttgccggctc
    10021 ctgtcggacc aacgatagct accatctcac caggcttaac ctctaaattg aaatttctaa
    10081 tcagaggatt gtctgctgta tagctaaaat caacctgatt aaaggacacc tgacctgtta
    10141 aatcatgttc taaatgctct tgggcaatag tcaattcatc tgcctcatca agcactgcaa
    10201 agatacgttc taaggatgac ttggcacttt gcagtggacc agccagctgt gttatggtct
    10261 gaataggctg actgatttgc caaatgtact gaacaaaggc ttgcatgttt gttcccgatt
    10321 gtcaggcggc ctgctatcac ctgtaagcca gcgattaagg caacaatcat gtaaacagaa
    10381 tctgaaataa aatgcagaac tggcatcatg atcccagaaa taaagctggc cttaaagcct
    10441 acttcttgta atcgctcagt gatctggtga aattcctcct ttgaggcttc ttcacgacca
    10501 tacagtttta aaatattaaa gccggtcaaa ttttcctgca caaagccatt catttctccc
    10561 aaaatattag cctgcgcttt aaaataaggc tgtgattttt ttaaaacaaa tcgagaagca
    10621 gcatatatca acgggatagc gataatcaca acagaggcta ggggggcatt aatatacaag
    10681 accatgccaa ccaccaaaat aagggtaaaa aaggcgttaa caatctgtaa aaaggactgc
    10741 tgtaaggcat tagagactgt ctcaacatca gaggtaaacc ggcctagcat atcgccgaac
    10801 tgatgcttat caaaataaga cacagggata cgattaattt tttgactgag gtctcgacga
    10861 agatcacaaa tgcttgattg cacagccctt gtcataaaat agtttgaacc ataagagcct
    10921 aactcgtaaa caagggccct aatgatatag agagctaaaa gaaaggcgat ataggtttta
    10981 ttaatgcctg caccagagac tccctttgct atgtctaata ggtttgcaga tagctctgtt
    11041 atcaccaagc caagaacaaa gggctctaag acactcatca cagcactgac tatttttaaa
    11101 ataatggcag ttattagtga gagcctatag gcactaaggt aggtccaaat tcttctaaac
    11161 acatgctttt cagtcattaa tccccctcct cttttgtcat gtcttccttg tttagctgag
    11221 aattggcaat ttcacgatag atggcattgc ttgtaagcaa ttcctcatgt gtacctcggc
    11281 caacaatttc tccctgatcc aagacaatga tttgatcagc atccataatc gtgcccaccc
    11341 tttgagccac aattaagacc gttgcatctt gtgtcacctc tttcagccgt ctgcgtaatt
    11401 cagcatctgt cttgtaatct agggcagaaa aggaatcgtc aaagatatag atgtctggct
    11461 gcttgaccac tgctctggca atagacaggc gctgcttttg ccctcctgat agattactgc
    11521 cggcctcagc tagatgggtt tgatagctct tttcacgact ggtaataaag tccttcgctt
    11581 gggaaacctc tgttgcctgc tcaagctcac tgtggctggc atctgactta ccatatttta
    11641 ggttttcctc aatggttcct gtaaatagca gggctttttg aggaataaag ccgattttag
    11701 aacgcagcgc ttttaattga taatccctga catcaatgcc atcaaccaag attctcccta
    11761 aggtcacgtc ataaaatcgt gggatcagat taaccaaaga tgattttcct gaacctgtcg
    11821 agccgataaa agcaatggtc tctccaggcc tagtcttaaa tgagatgtta tgtaaaactg
    11881 gactttccgt ttcacccgga taggcaaagg tcacgttatc aaattctaga taaccacgtg
    11941 ttgtgaacgc tgttatacca tcttcatttt taggaatcga aatcggcata tccagcactt
    12001 ccttgatacg cttgcttgac actgctgttt tagggtacat ggtaaagagg ttggcaaaca
    12061 ttaaaaatga aaaaagagca tgaaagctat attcgataaa ggccaccaaa tcaccaatct
    12121 taaactgccc ccttgccaag ggatccaagg caaaccagac gatccccaca atcatagcaa
    12181 tgataatttg cacaaataag ggctctgtta agcctgtcaa ggtaaatagt cgctttgaga
    12241 ttccagaata gtgatcattg cgcttattga agcgctcttc ttgaaagtct tctcttgcaa
    12301 aggctcgaat aactctcaga cctgtcaggt tttcacgcac caattggtta atacgatcaa
    12361 ggctctcctg ctgcttttct gataagggtc ttgtctttat cgcaacataa agcaccacaa
    12421 taactaaaaa aggcatggca acagccacaa tccaagccaa tgatggactg gttaaaaaga
    12481 tcatcaccac tgaaaagatc atcatcaaag gagttacgac acccagcctc aaggacattt
    12541 cagcaaattg catcaaaaca aaggcatcat ttgttatccg agtaaccagg gaggctatgc
    12601 caattttttc atattccgaa tgcgaataat cctgcaagca gctatacatg tcattacgta
    12661 aatccttgat catgttggtg gttagcttac ccgaagcata ggataaaatc acccgtccaa
    12721 tgacacctaa aagtacgata ataaacatca tcagagccca aaaataaaga gccctttgat
    12781 cctgctgcat aacgccttga tcaatcatac gagccaatat tgttggtagc cccagattga
    12841 ccagaacaaa taacaagcca cccacaatat cgaaacaaat ccatttaggt cttgttttta
    12901 aataggacca aattaaagcc attcatttcc tcccaaataa tagtgatatg aaaagaagcg
    12961 caagctagca cttctttttg tctataacta gtttaacaca aaaatatgaa attgacacat
    13021 aattaattat tcttctaatt cgcttaggta atcaaagcgc tcataggctt caagcagctc
    13081 aagattccgc tgatccagct ccttttgata ttgtgccaat tggtcgtaat cacttgccgc
    13141 tctgagcatt tgctcctcaa tagtagctat ttgttgctcg atagcagcta gcttttcttc
    13201 aatagctgcc cattcctttt tctcaagata ggacattctc tttttagagg tgacctgatg
    13261 gtcagtgcca gctttttgct cactgacagc aggctctatg acctctgctt caaaagcctt
    13321 ttcatctaaa tagtcgctat agttaccata gtattctctg atagctccat gctcaaaagc
    13381 caatactttt gttgcaacct tatccaagaa ataccgatca tgactcactg taatgaccgg
    13441 accagcaaat tgagctaaaa aatgctccaa cactgtcaag gttgcaatat ccaaatcatt
    13501 ggtcggctca tccagcagca ggacgttggg cttttcgatc aagagcttta gcaaatacag
    13561 tcttttttct ccccgcctga tagcttagcg attaaggagc catgactaga acgcggaaaa
    13621 agaaattgct ccaaaagctc actgatgcta gtggtgccaa cactggtctt gacctcatct
    13681 gccacctcct gcaaatagct aatcacgcgc ttgctgccgt ccatatcctt gatttgctgt
    13741 gaaaaataac caatacggat cgtctcgcca atctctagct gaccagctgt tggttttaag
    13801 tcaccagtca tcaagctaag cagggtggtc tttccagcac cgttagctcc aacaatgccg
    13861 atacggtcct tattttgaat gatcaggtta aaatgctcaa taatggcctg atcaccataa
    13921 gcaaaggaaa cctccttgaa attaatgacc ttcttgccaa tacgactggc ttcaaaggcc
    13981 atatctaatt gatctatagg cctttcctga tgaaggtcct tttttaactg ttcaaagcgg
    14041 ttaattctgg cctgctgctt ggtcgcacgc gcctgtggct gtgtcctcat ccaagccagc
    14101 tcctgtttat agagctgctt tttcttatgc aaatgagctg cttcgcgctc gtcttgctca
    14161 gccttcagac gcacataatc ctggtaattg ccctgatatt cagtcacatg agccttatcc
    14221 aattcaaaga tacgtgtggc tatactatcc aaaaaatagc gatcatgtgt aataaataga
    14281 acagtccttt tagaggtcct taagtaatga cttaaccaag cgatggtatc aatatccaaa
    14341 tgattggtcg gctcatctag cagcaacaaa tcactggctc caagcaagac ctgagccagc
    14401 tgtacccgac gtctcatacc accggacagg tcacccactc tctgatccag attgacaata
    14461 ccaagctttg ataagaccgt cttaacctca ctttcgatcg accaaacatc taatcgatcc
    14521 atctcagtca tcacctctgc tagcttttcc tgattgctat ctgaatagtc agccatcaac
    14581 agctcatatt ggcgaatcag ctgcatttcc tttaattcta gggacagaac agtatctaaa
    14641 acagactgat catcatcaaa gtccggctcc tgtgttaaat aagatatacg atagtcattt
    14701 gcctttgaaa aaggtgagcg gtcaccatca aagcccactt tttcagaaat aacatcaagc
    14761 aaggttgttt ttcctgtccc attgacacca ataatgccaa tgcgatcacc agcatgaata
    14821 ataaaggaaa tatcctgaaa aacggtctta tctccaacag acttcgtcag atgttcaacg
    14881 ataaaatcac tcatttagta gttcccttct aacaaaagcc tcaatgtgtt ctctttgatt
    14941 gacgagacgc ccctctacaa tggcctgctc aatctgattt aaaagcattc ccagctgtgg
    15001 tcctggcttc attccaagct cacgaatcag ataagagcca ttgaccacaa tatcatgctt
    15061 atcatggatc gtcagctcct gatacaagct ctcaacacgc ttggcctcac tgaccaagcc
    15121 ctgtgcctgt cgtaaatcgt caacgagtaa agccaagtcc ttgccaaacg agtaaatatc
    15181 ccatttttct agctgtcttt cttggcgaat ctgataaaga gaggccatca tcgtaaccct
    15241 acgctgaaaa tcattagagg ttttccaagc ctttaaaaag gctttaggct gatcaagctc
    15301 cagcataacc agcaaatagg cccaagcctg atgattgtcc tgaaacacat aatccgctgc
    15361 taaggttttc aggtactttt gcagggcttc ttccttgccc actaagcctg gcaaatagtt
    15421 aaaggcctga catgccacca tagctaagat acctttacgc cattttgggg ccattaaaag
    15481 cttatcaagc tcaataaaag agcgctcaat agaaatcttc tccagcaagg gagcatggct
    15541 tttcattgct tcaaaggtct cagcctcaat atcaaaatct aagctggcag caaaccgaaa
    15601 gcctcgcata atccgcaggg catcctcctc aaagcgctcc tgaggccttc caacagctct
    15661 tagaagctta tgctttaggt cctctaagcc attaaagata tcaataacct gtccgtcctc
    15721 atctaaggca agagcattga cagtaaaatc ccttcgtttt aaatcctctt ccaaggaccg
    15781 aacaaaggat acctgactag ggcgcctata atccacataa acgtcctcag ttcgaaacgt
    15841 tgtgatctca tattcactgc cattttctaa aacaagcact gtgccatgct caatcccaac
    15901 atcaattgtt cttaagaaaa tagcctttgt ctcctctgga tagcagctag cagctatatc
    15961 aacatcatga ataggcctgt ttaataagct atccctcaca cttccaccaa caaaataggc
    16021 ctcaaagcca gcctgcttga tttttttcac tattggtaaa gccttctgaa attcagaagg
    16081 cattgtcatt aatgttatca tgttttaatc taccacctaa aagctcctag agccttgtca
    16141 tatgcttccc gttaaaggct gtcatatcaa gctcagattg gtcatgggca agcctcttta
    16201 gacaagaggc gttatgccaa aggcaacagc tccttctcca agatgggctg caatcactgc
    16261 accaaaatga acctcctcaa cagggcaggt atagccatta tccaacaaga gctgctttaa
    16321 gatatcagcc ttatcctgcg ctctagcatg gataattgat acctcgtact gaccactagc
    16381 tgtcaattcc tttaagatat caaccaagcg cttcatggcc tttttttccg ttctaacctt
    16441 ttcatagacg acaatctttc cttcactatc aaagcgaaga attggcttga tgctgagcaa
    16501 atttcccagc aaagcagaac cgtttgataa gcgtcctccc ttgaccaaat gattcaaatc
    16561 atcaaccatg ataaaggctg tggttccagc gatttgctct tctagcttat ccataatctc
    16621 tgcaaagctc aagccttgct gagaccactc taaagcattt ctaaccatgc tgcctaatga
    16681 tgctgaggtg attttactat ctggaaaagc aatggtcaac tcagggtgct cctcgatgag
    16741 aaattgaata ttttgccaaa atcctgaaat accactagcc aagaacaagc caatcacatg
    16801 agtatagtgc tcagttgaca gacgccctag taaatcatct aattcagaga ggctgggctg
    16861 actggttttt ggcagctctt gagattctct catgctttgg taaaaggctt caatggtcag
    16921 gttttgtcct tcgacatagc tttgaccatc tatgattaca ggtatgtcta atacaaaaat
    16981 atcggcatgc tccgctaact gctctggaag gtgagctgta ttatcagtta ttattgctaa
    17041 cttcattaac ttttaaactc caaattaata ccaggacgat ccaaggcaat ttctgtcact
    17101 tcgtaggtca agcgcttcac catgtctaat aatggagcag ccaaggattc gacctcctct
    17161 tgtgtaaatt cactaggctt atccaccaag cgtcctaaaa tacgaaccat ctgtgaaatc
    17221 acaccactaa tcacaaactc ttccttgaca atgacaaatt gtaaaacaga aacaatagcc
    17281 gtctctttat tttccacatc tttattaatc aactgaaagg ttacttcaaa gtttgtttcc
    17341 ggtgttccat tttctttttc ccattctaaa tttctggcgt cataatggta ctgattgaca
    17401 aattcttttt cacgtactaa ttgcatgatt tcgttctcct taatggcgat atgacccatt
    17461 atagcataga tttgacgaat attaaagtag acttaaacca gtattttgga taattttttt
    17521 ccagaccttg tcacttcaat aaatataaac ctgccttcta tcaaccaatc aatctcctac
    17581 aacaaaaaaa caccccaagg tgtactgccc ccaaaaagtt gaacgaataa ttattgaaag
    17641 gatttagttc tgtattgaac agggctaagt ccttttagtt tagttttgat tcgtttattg
    17701 ttg
//
LOCUS       DARYXW010000042        17368 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.042, whole genome shotgun sequence.
ACCESSION   DARYXW010000042 DARYXW010000000
VERSION     DARYXW010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17368)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17368)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17368
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.042"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            40..651
                     /locus_tag="TV191_001136"
     CDS             40..651
                     /locus_tag="TV191_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HEL1507655.1"
                     /translation="MFKQDILKQRYFSFGIVAAAIALLAVVFAFSSENVNTDSYAKAS
                     DTKVVKKHHKTKKSTVAKAATKEQPAEQAEPSSADAAPAQESVASEVASPAVQEAAPQ
                     AQYAATPVAYSNGVILSNGNTAGAIGSEAAAQMAAATGVPQATWEAIIARESNGNPNA
                     ANPSGASGLFQTMPGWGSTATVQDQVNSALNAYRAQGLSAWGY"
     gene            complement(712..1347)
                     /locus_tag="TV191_001137"
     CDS             complement(712..1347)
                     /locus_tag="TV191_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase-like protein"
                     /protein_id="HEL1507656.1"
                     /translation="MKAILFDLDGTLVDSSIGILNAFEYTFQKMKIPCPDHSILSSYI
                     GPPLEATFSAFFRNQHDVEVAITHFRDFYRELGIYQARLYSGITELLDNLSQEGLDLY
                     VTTSKYEPMARQMLQDLTISHYFKAILGSISNRCHKLDIVKACLQDFAINKKEAIIVG
                     DTKFDMIGGKQAGITRLGVTWGFGCQEDLQAHGAQYIGHTPQEVIEIIQSL"
     gene            complement(1381..2253)
                     /gene="sdaAA"
                     /locus_tag="TV191_001138"
     CDS             complement(1381..2253)
                     /gene="sdaAA"
                     /locus_tag="TV191_001138"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEL1507657.1"
                     /translation="MFYTIEELVKQADDRFDGNVAELMIATEVEMTGRSRAEILSIMS
                     QHLQVMKDSVVSGLTATKSISGLTGGDALKMDHYIKKGKGLSDQTILTAVRNAMAVNE
                     LNAKMGLVCATPTAGSAGCLPAVLAVAIDKLKLSEKEQLDFLFTAGAFGLVIGNNASI
                     SGAEGGCQAEVGSASAMSAAALVKAAGGTAYQASQAVAFVIKNLLGLVCDPVAGLVEV
                     PCVKRNALGSSFALVAADMALANIQSQIPVDEVVDAMYQVGAAMPTAFKETAEGGLAA
                     TPTGRRYSKEIFGD"
     gene            complement(2265..2936)
                     /gene="sdaAB"
                     /locus_tag="TV191_001139"
     CDS             complement(2265..2936)
                     /gene="sdaAB"
                     /locus_tag="TV191_001139"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEL1507658.1"
                     /translation="MNTQKFQSVFDIIGPVMIGPSSSHTAGAVRIGKVVHSIFGEIPD
                     EVTFHLYNSFAKTYQGHGTDKALVAGIMGMDTDNPNIKNSLEIAHQKGIKIYWDILKD
                     SNAPHPNTVKISVKKADKAMSITGVSIGGGNIQVTELNGFSVSLSMNTPTLIIVHQDI
                     PGMIAKVTDILSASDINIAQMTVTRESAGEKAIMIIEVDSRDCQVAVKQIATIPNLHN
                     VNFFD"
     gene            3217..4341
                     /gene="mnmA"
                     /locus_tag="TV191_001140"
     CDS             3217..4341
                     /gene="mnmA"
                     /locus_tag="TV191_001140"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEL1507659.1"
                     /translation="MMTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGVFMKNWDD
                     TDEFGVCTATEDYKDVAAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRSGRTPNPDV
                     MCNKEIKFKAFLDYAMTLGADYVATGHYAQIKRDENGVVHMLRGLDKGKDQTYFLSQL
                     SQEQLQKTMFPLGHLQKSEVRAIAEQAGLATAKKKDSTGICFISEKNFKTFLSHYLPA
                     QKGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQQGGDNKPWFVVGKDLSQNILYVG
                     QGFYHESLMSTSLDASVIQFTREVPEEFTLECTAKFRYRQPDSKVTVHVKKDKAKVVF
                     AEPQRAITPGQAVVFYDGHECLGGGIIDMAYKDGEPCQYI"
     gene            4546..5010
                     /locus_tag="TV191_001141"
     CDS             4546..5010
                     /locus_tag="TV191_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HEL1507660.1"
                     /translation="MVQDFRTRIADHSFGVRASALIIKDGYIYLAKSPKEDYYLLGGA
                     IHVGESTEEAVKREVLEEVGAEVSVAQLAFVVENQFCLEGVNFHQIEFHYIVSLLSDS
                     SPSVVEGDCTRVCEWVALDDLDKIRLNPSCLKRAIKHWDRQPQHIKHIEIKE"
     gene            5013..6911
                     /gene="mnmG"
                     /locus_tag="TV191_001142"
     CDS             5013..6911
                     /gene="mnmG"
                     /locus_tag="TV191_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEL1507661.1"
                     /translation="MVHEFTESYDVIVVGAGHAGVEASLAASRMGCKTLLATINLDML
                     AFMPCNPSIGGSAKGIVVREIDALGGEMGKNIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KSLYAREMKHTVEKQENLTLRQSMIDDILVENGRVVGVLTATGQKYAAQAVIITTGTA
                     LRGEIILGELKYSSGPNNSLASVTLADNLKKLGLEIGRFKTGTPPRVKASSIDYEVTE
                     IQPGDVTPNHFSFMSKDKDYLANQIPCWLTYTNQISHDIITKNLYRAPMFSGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGFDTEEVYVQGLSTSLPEDVQKELVHSIKGL
                     ENAEMMRTGYAIEYDIVLPHQLRATLETKMISGLFTAGQTNGTSGYEEAAGQGLVAGI
                     NAALKVQGKPELILKRSDAYIGVMIDDLVTKGTLEPYRLLTSRAEYRLILRHDNADMR
                     LTEIGRQIGLVDDERWSAFEIKKNQFDNELKRLDSIKLKPIKETNARVQKLGFKSLTD
                     AMTAKEFMRRPEVDYATVVSFIGPAAEGLDAKLIELLETEIKYEGYIKKALDQVAKMK
                     RMEEKRIPKTIDWDAIDSIATEARQKFKKINPETIGQASRISGVNPADISILMVYLEG
                     NGKARRKT"
     gene            6999..8975
                     /locus_tag="TV191_001143"
     CDS             6999..8975
                     /locus_tag="TV191_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEL1507662.1"
                     /translation="MKRFRFETIHLIMMELILFGLLALCVRIMQSKMLITLAIFLVLL
                     FVAALLWYQKKVYELSDLDHIELLNEQTENNLKTLLDNMPVGVIQFDQETNAIEWYNP
                     YAELIFTDEAGFLQEQMIQQLLTDKRKSDISQTFEVSGNRYTSYIDVASGIFYFFDSS
                     VGSRQSADSSLLKPVIGIISVDNYDDITDDLSDADTSKINSFVANFIAEFMESKQVFY
                     RRVNMDRFYFFTDYKILKGLMDDKFSILEQFRKEAQEAQLPLTLSMGISFGEENHCQI
                     GQVALENLNIALVRGGDQIVIRENADHTNPVYFGGGSVSTVKRSRTRTRAMMTAISDR
                     IKMVDNVFIVGHRKLDMDALGSAVGMQFFASNIIENSFAVYNPDEMSPDIERAIERLQ
                     ADGKTRLISISQAMGLTTPRSLLVMVDHSKISLTLSKEFYEQFQDVIVVDHHRRDDDF
                     PDNAILTFIESGASSAAELVTELIQFQNAKKRLNKIQASVLMAGIMLDTKNFSTRVTS
                     RTFDVASYLRSRGSDSVEIQNISATDFDDYKQVNEIILRGERLSDSIIVATGLAGQYY
                     SNVIASKAADTILSMAHIEASFVIVETGADKIAISARSRSKINVQRMMEKLGGGGHFN
                     LAACQMKHISLSEAKQLLLETIDNTMKETREVES"
     gene            8972..9424
                     /gene="rplI"
                     /locus_tag="TV191_001144"
     CDS             8972..9424
                     /gene="rplI"
                     /locus_tag="TV191_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEL1507663.1"
                     /translation="MKVIFLVDVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEASSQAI
                     GQLRGQQKAEEKAQAEILAEAKAVKKILDDEKTRVQFKEKVGPDGRTFGSITAKKISE
                     ELQKQFKVKVDKRHIVLDHPIRAIGLIEVPVKLHKEVTAEIKLNIAEA"
     gene            9445..10821
                     /gene="dnaB"
                     /locus_tag="TV191_001145"
     CDS             9445..10821
                     /gene="dnaB"
                     /locus_tag="TV191_001145"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEL1507664.1"
                     /translation="MEVLSLPEVAELRVQPQDLLAEQSVLGSIFISPDKLITVREFIG
                     PEDFYKYSHKVIFRAMIRLSDRNDAIDATTVRTILDDQGDLQHIGGLSYIVELVNSVP
                     TSANAEYYAKIVAEKAMLRDIINRLTETVNLAYEGASDSEDIIASAEKALVDISEHSN
                     RSGFRKISDVLKINYENLEVRSKQTSDVTGLPTGFRDLDKITTGLHPDQLIILAARPA
                     VGKTAFVLNIAQNVGTKQKRAVAIFSLEMGAESLVDRMLAAEGMVNSHSLRTGQLTDQ
                     DWNNVTIAQGALAEAPIYIDDTPGIKITEIRARARKLSQEVEGGLGLIVIDYLQLITG
                     TRPENRQQEVSDISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIE
                     QDADIVAFLYRDDYYRKESDSTEEALEDNTIEVILEKNRAGARGTVKLMFQKEYNKFS
                     TIAQFEER"
     gene            10838..11110
                     /locus_tag="TV191_001146"
     CDS             10838..11110
                     /locus_tag="TV191_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HEL1507665.1"
                     /translation="MSDAFTDVAKMKKIKEDIKAHEGQLVELTLENGRKREKNKVGRL
                     IEVYPSLFIIEYQGNPDASGEANNSYVESYTYSDILTEKTLIRYFD"
     gene            11634..12245
                     /gene="rpsD"
                     /locus_tag="TV191_001147"
     CDS             11634..12245
                     /gene="rpsD"
                     /locus_tag="TV191_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEL1507666.1"
                     /translation="MSRYTGPSWKQSRRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFSYGMGEKQFRNLFVQATKIKEGTLGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSFRVEIGQVISVREKSMKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(12452..12985)
                     /locus_tag="TV191_001148"
     CDS             complement(12452..12985)
                     /locus_tag="TV191_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEL1507667.1"
                     /translation="MDSRKQQTKKAILNAMVSLLKTESFDDVTTVQLAKMAGISRSSF
                     YTHYKDKYEMIDYYQQTFFHKLEYIFEKEYQNKEHAFLEVFEFLKREQLLSALLSSNG
                     TREIQSFIINKVRLLITTDLQDKFSKDILSPTEKEYRSIYLAHAFFGVCQSWIAKGKK
                     ESPQEMTRFVLKMLSKT"
     gene            13117..15399
                     /locus_tag="TV191_001149"
     CDS             13117..15399
                     /locus_tag="TV191_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HEL1507668.1"
                     /translation="MLEGLKAIIKNRKLVVTMIGVALVPALYNLSFLGSMWDPYGRVD
                     QLPVAVVNQDKPAYLNNKRLTIGNDMVDNMSKNKELDYHFVAADTAQKGLEKGRYYMT
                     ITLPKDLSQKATTLLDQQPEKLIVSYQTSKGHSFIASKMGESAMNHLREAVSKNIRKT
                     YITSVFKSMHQLQSGLKEASNGGQQLAAGLVIARASSQLMSRHLNTLSESSARLSQGA
                     GNLSSGIAAYTAGVGQLDTAGLGQLAADMPAYLDGVSRLSKGANQLNAGLTQLALGSD
                     LSQDKQANIQALMASLPKLNQAIQQLKTNLSLSLAPNVDSGAIAKHLADMTRLVQELV
                     VDDTADKNNQLAALQATATYQGLNSEQQEELSSAISNTSTKVTISAKAMLTSLQAMSE
                     ELEAMSTSAGVADQLRDFKALVNQLAYQADQILPSTGKALSELSTGLRAVHSATTAQL
                     LSGSQALAGGFNQLTAKNEALTAGLSTLATGATALNHQSSQLLAGGQQLTVGANQLAF
                     GANQLSSGSSQLTDGLTTLSTGLSSLTTSLSKASDQLSMAWVEDQNADMVSDPVALSE
                     KDKDKVRTNGIGMAPYMIAVSLMVVALSTNIIFAEALSGKPIKDRWDWAKQKLLINGM
                     ISTVGSVILYAALQLLGFEANDGIKTLGFIMLSGWALMALVTALVSWDARYGAFASLI
                     MLLLQVGAAGGSYPIELSGQIFQILHPYLPMSYIVSGLRQTISLTAQIGLETSVLVGF
                     LLSFMAIGVLIYRPKDKQSS"
     gene            complement(15503..16558)
                     /locus_tag="TV191_001150"
     CDS             complement(15503..16558)
                     /locus_tag="TV191_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HEL1507669.1"
                     /translation="MTKQDFLDKLKQQINHLPQKDYQEIIDHFTEYFDEAGPDHEQAI
                     LKELGNPEDIAKELLKALDLPEKTDEDDWTNWEVDNKTKSEASSQKLEPIVDIRYSLL
                     NHDLTIETADIPYPTISYDDNRITISQDSDGMLNIIEDSAVQTIQYGFHFLDRWLAKY
                     QPITLTLPVNHHLKKISGESDNNDVTIRHIHCDSIVSNTYNGTISISHLSDSTVNLSS
                     KNGNIILEHCNIQSSKCQAKNANLSCDNSTLINCQLNNNNGNIRLEASQLTETFIENK
                     NGNIIGQQLSFSNDITIINKNGIIDINCPRENLIYYDVKASNNNGFVTISQEAGRQTP
                     FKAQLTISNNNGLISVS"
     gene            complement(16577..17002)
                     /locus_tag="TV191_001151"
     CDS             complement(16577..17002)
                     /locus_tag="TV191_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507670.1"
                     /translation="MTRDEYLAELDKYLRKLPKADYYEAAENSSQLELNDGSIKDSSI
                     TVADTKEENDYDYTDPSELAINHVTIKEKNTINGGDININTTLANPRDIAYHVTTRGN
                     IKLSSRFSNAKLNTDAATGATSFHSDIANTVNQSDLSIH"
     gene            complement(16989..17315)
                     /locus_tag="TV191_001152"
     CDS             complement(16989..17315)
                     /locus_tag="TV191_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019314866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEL1507671.1"
                     /translation="MYFPVSATLIEFLILSIVDKHDSYGYDISQTIKLVANIRESTLY
                     PILKKLEKSDYLTTYSQEHQGRKRNYYTITAKGEKQLIFLKEEWQSYKATLDGIIEGR
                     LRHDKR"
BASE COUNT         5042 a         3163 c         3845 g         5318 t
ORIGIN      
        1 gttaatatgg ataacagaga aaagtgaggt atttatttaa tgtttaaaca agacattttg
       61 aaacaacgtt attttagttt tggcattgta gcagctgcta ttgctttgct cgcagtagtt
      121 tttgcttttt caagtgaaaa tgtaaacact gattcctatg ctaaagcttc tgatactaag
      181 gttgtgaaga aacatcataa aacaaaaaaa tcaacagtag caaaggctgc aaccaaggag
      241 cagccagctg agcaggcaga gccttcctct gctgatgcag caccagctca ggaatcagta
      301 gcttctgagg tagctagtcc tgctgtgcaa gaggctgctc ctcaagctca gtatgcagct
      361 acaccagtgg cttatagcaa tggagtaatc ctttctaacg gcaataccgc aggggctatc
      421 ggtagtgaag cagcagctca aatggcggca gctactggtg ttccacaagc tacttgggaa
      481 gccattatcg ctcgtgagtc aaatggaaac cctaacgcag ctaatccttc aggtgcttca
      541 ggattattcc aaaccatgcc aggctgggga tcaactgcaa ccgttcagga tcaggtaaat
      601 tcagccttaa atgcctatcg tgcacagggc ttatcagctt ggggctacta agaacagata
      661 acagcgttaa aaacctatca tcttgtgtga tgataggttt ttagtatcgt tttacaatga
      721 ctggataatc tcaatcacct cttggggtgt gtgtccaatg tattgtgcgc catgtgcttg
      781 taaatcctct tgacaaccaa atccccaagt aactccaagt cttgtaatgc ctgcttgttt
      841 accaccaatc atgtcaaatt tggtatctcc aacaattata gcttcttttt tattaatagc
      901 aaaatcttgt aagcatgcct tgacgatatc caacttgtga caccgattag aaatagagcc
      961 taggatagct ttgaaataat ggctaatcgt taaatcctga agcatttgcc ttgccatagg
     1021 ttcatattta ctagttgtca catagaggtc aagaccttct tgcgagagat tatctaatag
     1081 ctctgtgatt ccagaataaa gccttgcttg gtaaatgcct aattccctgt aaaaatctct
     1141 aaagtgtgtt atagcaacct cgacatcatg ctgattccta aaaaatgctg aaaaggtcgc
     1201 ttctaagggt ggtccgatgt aagacgataa tatgctatga tcaggacaag ggattttcat
     1261 tttttgaaag gtgtattcaa aggcatttag tattcctata ctagaatcca ccaaagtacc
     1321 atctaagtca aataggattg ctttcatgac gtctcctcag tctatcgtta cttgattata
     1381 ttagtctccg aaaatttctt tactataccg tctacctgtt ggggttgctg ctaatcctcc
     1441 ctcagctgtc tccttaaagg ctgttggcat tgcggcacca acctgataca tagcatcaac
     1501 aacctcatct acaggaattt gtgactgaat attcgctaat gccatatcag cagcaacaag
     1561 agcaaagctt gatcctaatg cattacgctt aacacaggga acttcgacta agccagcaac
     1621 aggatcacaa accaatccca atagattttt gatcacaaag gctaccgctt ggctagcctg
     1681 ataagcggta ccacctgctg ccttaacaag ggctgcagca ctcattgcag aggcagagcc
     1741 cacctcggct tgacagcctc cttctgctcc ggagatagag gcattatttc caatgactaa
     1801 gccaaaggca cctgctgtaa agagaaagtc cagctgttcc ttttctgata gcttgagctt
     1861 atcaatagca acagcaagga cagcaggtag acagcctgca cttccagcag tcggggttgc
     1921 acaaacaagt cccatttttg catttagctc attgacagcc atagcatttc tcacagctgt
     1981 taaaatggtt tgatctgaaa gcccctttcc ttttttgatg taatgatcca tcttaagagc
     2041 atcaccgcca gtcaatccgc taatagattt ggttgctgtc aatccgctga caacagaatc
     2101 cttcattacc tgtaaatgct gtgacatgat ggataggatt tctgccctgc ttcgaccagt
     2161 catttcaacc tctgtagcaa tcatcagctc tgctacatta ccatcaaacc tatcatcagc
     2221 ctgcttgaca agctcttcaa ttgtgtaaaa cataatatac ctttctagtc aaagaaattg
     2281 acattatgca gattaggaat agttgcaatc tgcttgacag caacttgaca atcacgagaa
     2341 tcaacctcaa taatcataat ggctttctca cctgcacttt cacgagtcac agtcatttga
     2401 gcgatattaa tatcactagc tgacaatata tctgtaacct tagcaatcat tccggggata
     2461 tcttgatgga caataatcaa ggttggagta ttcatagaca aggaaacaga aaaaccattt
     2521 agctctgtga cctgaatgtt tcctcctcca attgacacac ctgtaatgct cattgcttta
     2581 tcagcctttt tgacactaat ctttacagta ttggggtggg gagcattgct atcctttaaa
     2641 atatcccaat aaattttaat gcccttttga tgagcaattt caagagaatt cttgatgttt
     2701 ggattatccg tatccatgcc cataatacca gctactagtg ccttgtcggt accatggcct
     2761 tgataggtct tagcaaatga attgtataga tgaaaggtca cctcatcagg aatttctcca
     2821 aaaatggagt ggacaacctt tccgattcta acagcaccag cggtatgact gctcgatggt
     2881 ccaatcatca ctggtccaat gatgtcaaaa actgattgaa atttttgtgt gttcatatat
     2941 gctccatgct ctttttatcc tttttattat aacaaatcgc taatcaaatg tcgtttgtta
     3001 tgaaaaaaga tattgttgga aataagagac aatactgtta taatagtcat gcgtctagcg
     3061 gcgcttcaaa tcgaccttca aatcgagctt tgagaaaaca cttggacaaa gacaaaaaat
     3121 atagaaatga accatttgct agagtcttgt ttaggcaagt tgattcgttc tattcttttt
     3181 ctcatgtcct tgtatcttat attgatggga gaataaatga tgacagataa ctcgaaaaca
     3241 cgtgttgttg ttggcatgag tggcggtgtt gattcatctg taactgcctt gctgttaaag
     3301 gagcagggat atgatgtgat tggcgtcttt atgaagaatt gggacgatac agatgaattt
     3361 ggtgtttgta cggcgactga ggattataaa gatgtggcag ccgtagccga tcagattggt
     3421 attccttact attctgttaa ttttgaaaaa gagtattggg atagagtgtt tgagtatttc
     3481 ctagcagaat accgttcagg acgcacccca aatcctgatg tcatgtgcaa taaggagata
     3541 aagtttaaag cctttcttga ttatgcgatg acattgggtg ctgattatgt ggcaacaggt
     3601 cactatgccc aaatcaaacg tgatgagaat ggtgtagtcc atatgctgcg tggtcttgat
     3661 aagggtaagg atcaaaccta ttttttaagc caactatcac aagagcaact ccaaaaaacc
     3721 atgtttccct tggggcacct gcaaaaatca gaggtacgtg ctattgctga acaagcaggc
     3781 cttgcaacag caaagaaaaa agactcaaca gggatttgtt ttattagtga gaagaatttt
     3841 aagacctttc ttagccatta tttaccagct caaaaggggc gtatgatgac tgttgatggt
     3901 cgtgatatgg gagagcatgc aggcttgatg tattatacta ttggccaacg tgggggactt
     3961 ggcattggtg gtcagcaggg tggagataac aagccttggt ttgttgttgg aaaagacctt
     4021 tcacaaaata tcctttatgt tggtcaaggc ttttaccacg agtccttaat gtcaactagt
     4081 cttgacgctt ctgtcattca gtttacaaga gaagttcctg aagaattcac cttagaatgc
     4141 acagcaaagt tccgctatcg tcagccagat tctaaggtga cggttcatgt caagaaagac
     4201 aaagctaagg ttgtttttgc tgagcctcag cgtgcgatta cacctggtca agcagtcgtt
     4261 ttttatgatg gtcatgagtg tcttggtggt ggtattattg atatggcgta taaagatggc
     4321 gagccttgtc aatatattta gcttgacatg ttaattgaca gatgtgtcaa taaagttgac
     4381 ggttttgtca tctgataagt cttgacaagc tggcagattt tgatagaata aggttaacaa
     4441 taacgatgat ggtcaaagct catgggaatt gtaagtcttt ttggcttaca gctttctcag
     4501 gttttgacta tttttatagc ttaaaaacag tgtcaaggag aaaagatggt tcaggatttt
     4561 agaacaagga tagcagacca tagctttggt gttagggctt cagcgttaat aattaaggat
     4621 ggctatattt atcttgccaa atcacccaaa gaggactatt atcttttagg tggtgctatt
     4681 catgttggag aaagcacaga agaagctgtc aagcgtgagg ttctagagga ggtaggagct
     4741 gaggtttcag ttgctcagtt agcctttgtg gttgaaaatc aattttgtct agaaggagtg
     4801 aactttcatc agattgagtt tcattatatt gtgagtctat tatctgattc tagcccttct
     4861 gtagttgagg gtgattgtac tagggtttgt gagtgggttg ctcttgatga tctagataag
     4921 ataaggctca atcctagttg tttaaaaagg gctataaagc attgggacag gcagcctcag
     4981 catataaaac atattgagat aaaggagtag atatggtaca tgaatttaca gaatcctacg
     5041 atgtcatcgt tgtaggagca ggacatgcag gtgttgaagc cagcttagcg gctagccgta
     5101 tggggtgtaa aaccttatta gcaacgataa atcttgatat gctggctttt atgccatgca
     5161 atccctctat tggagggtca gctaagggta ttgttgttcg cgaaattgat gctcttggtg
     5221 gagagatggg gaaaaacatt gacaaaacct atatccaaat gaaaatgctc aatacaggta
     5281 agggaccggc agttcgagca ttacgagctc aagcagataa aagcttgtat gcacgtgaga
     5341 tgaagcatac tgttgaaaag caagaaaacc tcactcttcg ccagtctatg attgatgata
     5401 ttttagtaga aaatggtagg gttgttggag tgctgacagc aacagggcaa aaatatgcag
     5461 ctcaggcagt gatcataaca acaggtacag ctcttcgtgg tgagattatc cttggagaat
     5521 tgaaatattc gtctggcccg aataacagct tggcctcagt gacactagct gataatttga
     5581 aaaagcttgg tcttgaaatt ggccgcttta agacaggaac cccaccacgt gtcaaggctt
     5641 cttctattga ttatgaggtg acagagattc agcctggtga tgtgactcca aatcattttt
     5701 cctttatgtc taaggacaaa gattatttgg ctaatcagat tccttgctgg ctgacctaca
     5761 ctaatcagat tagtcatgat atcatcacta aaaacctata tcgagcacct atgttttcag
     5821 gagtcgtcaa gggagtgggc ccacgctatt gtccatcaat tgaggataag attgtacgat
     5881 ttgctgataa agagcgtcat cagctctttt tagaaccaga aggctttgac actgaggagg
     5941 tctatgttca aggtctatcc acaagtcttc ctgaggacgt ccaaaaggaa ttggttcact
     6001 ctattaaggg gcttgaaaat gctgagatga tgagaacagg ctatgctatt gagtatgaca
     6061 ttgtattacc tcatcagctt cgtgctaccc ttgaaacaaa gatgatttca gggcttttta
     6121 cagctgggca aaccaatgga acctcaggct atgaggaagc tgctggtcaa ggccttgtcg
     6181 ctggtatcaa tgctgctttg aaggttcagg gtaagcctga gctcatttta aagcgcagcg
     6241 acgcttatat tggtgtaatg attgatgatt tggtaaccaa aggaaccttg gagccttacc
     6301 gtttgctgac atcacgcgca gaatatcgtc ttatccttcg tcatgataat gcggacatgc
     6361 gattgactga aattggtcgt cagattggct tggttgacga tgagcgttgg tctgcctttg
     6421 aaatcaagaa aaatcaattt gacaatgaat taaagaggct agatagtatc aaattaaagc
     6481 caatcaaaga aaccaatgct cgtgttcaaa agcttggctt taagtccttg acggacgcaa
     6541 tgacagctaa ggaatttatg cgtcgaccag aggttgacta tgccactgta gtgtcattta
     6601 taggtcctgc tgctgaggga ttagatgcta agctgattga gctactagaa actgagatca
     6661 aatacgaagg ctatatcaaa aaggcccttg atcaggttgc taaaatgaag cgtatggagg
     6721 aaaagcggat tcctaagacc attgattggg acgctattga ctcaattgct actgaggcaa
     6781 ggcaaaaatt taagaaaatc aatccagaaa ccattggtca ggctagtcgc atttcaggtg
     6841 taaatccggc agatattagc attttaatgg tttaccttga aggtaatgga aaggctcgcc
     6901 gtaaaacata atagtcatca aattgtaatc tcaaaaccac tgacagctct gtatttcagg
     6961 gctgttttat ggtataatac gggattaaga ggttaaagat gaaaagattt cgttttgaaa
     7021 ccattcattt aattatgatg gagttgattt tattcggctt actagcctta tgtgttagaa
     7081 tcatgcaatc aaaaatgctg attacactag ctattttttt agtgttgttg tttgttgcgg
     7141 ccttgctttg gtatcaaaaa aaggtttacg aattgtctga tttagaccac attgagctat
     7201 tgaacgaaca aacagaaaat aatttaaaaa cattactgga taacatgcca gttggtgtta
     7261 ttcagtttga tcaagaaacc aatgctattg aatggtacaa tccttacgca gagctgattt
     7321 tcactgatga ggccggtttt ttacaggaac agatgatcca acagcttctc actgataagc
     7381 gtaaaagtga tatttctcaa acctttgagg tttctggcaa tcgatacacg tcttatattg
     7441 atgtggcatc aggtattttt tacttttttg atagctctgt tggtagtaga caatcagcag
     7501 attctagctt gctaaagcca gttattggta ttatttctgt ggataattat gacgacatta
     7561 cagatgactt atctgatgct gatacgtcaa agataaattc atttgtggct aatttcatag
     7621 ctgagtttat ggagtctaag caggtatttt atcgacgtgt taatatggat cgtttttact
     7681 tttttacaga ctataagatc ttaaaagggc tgatggacga taagttttct attttagagc
     7741 agttccgaaa ggaagcccaa gaagcgcagc taccattgac cctaagtatg ggcatttcct
     7801 ttggagagga aaatcattgt caaattggtc aggttgctct tgagaatctg aatattgctc
     7861 ttgtccgagg cggagatcag attgttattc gtgaaaatgc agaccataca aatccggtct
     7921 attttggtgg cggctctgtt tctacggtta aacgctctag aactaggacg cgtgccatga
     7981 tgacagctat ttcagaccgt atcaaaatgg ttgataatgt gtttatcgta ggtcaccgta
     8041 aactggacat ggacgcctta ggctcggctg ttggcatgca attttttgct agtaacatta
     8101 ttgaaaacag ctttgctgtc tataatccgg atgagatgag tccagacatt gaaagagcta
     8161 ttgagcgctt acaggctgat ggtaagacac gtcttatcag tatttctcaa gcaatggggc
     8221 ttacgacccc tagatcactg ttagtaatgg tggaccactc taagatttcc ttaaccttgt
     8281 ctaaggaatt ttacgagcaa tttcaagatg ttattgtcgt tgatcatcac cgaagagatg
     8341 atgattttcc agataatgct atcttgacct ttattgaaag tggtgcaagc agtgccgcag
     8401 agctagtgac agaattaatc cagtttcaaa atgcgaagaa gcgcttaaac aagattcaag
     8461 caagtgtttt gatggctggt attatgctgg atactaagaa tttttcaaca cgtgtcacca
     8521 gtagaacctt tgatgttgcc agttatttac gaagcagagg tagtgatagc gtcgaaattc
     8581 aaaatatttc agcaactgat tttgatgact ataagcaggt taatgagatc attctcagag
     8641 gtgagcgcct tagcgactcc attatcgttg caactgggct tgctgggcaa tattatagta
     8701 atgtcattgc tagtaaggca gcagatacca tactatcaat ggcccatatt gaggctagct
     8761 ttgttattgt agagacagga gctgataaga ttgctatatc agcaagaagt cgtagtaaga
     8821 tcaatgtcca aagaatgatg gaaaagcttg gcggcggagg acatttcaac ttagcagcgt
     8881 gtcagatgaa gcatatcagt cttagcgagg ctaagcagct gttactagaa acaattgata
     8941 acacaatgaa agaaacaaga gaggtagagt catgaaagtc atttttttag ttgacgttaa
     9001 aggaaaagga aaaaaaggag aaatcaagga ggttcccact ggttatgctc agaattttct
     9061 gattaagaaa aatttagcaa aggaagctag cagtcaagca attggccagc taagagggca
     9121 gcaaaaagct gaggaaaaag cccaggctga aatcctagca gaggctaagg ctgttaagaa
     9181 aatcttagat gacgaaaaaa ctcgtgtcca gtttaaggaa aaggttggac cagatgggcg
     9241 tacctttggc tcaattacag ctaagaaaat ttccgaggaa ttgcaaaagc aatttaaggt
     9301 caaggttgac aagcgtcata ttgttttaga tcaccctatt cgtgctattg gtcttatcga
     9361 agtgccagtt aagctgcata aagaagtgac agctgaaata aaactaaaca ttgctgaggc
     9421 atagcacatc agcctaaaaa agatttggag gtgctgagtt tgcctgaagt tgctgagtta
     9481 cgagttcaac cccaagattt attggcagag cagtctgtac taggctctat ctttatttcc
     9541 ccagacaagt tgattaccgt tagagaattt atcggtccag aggattttta taagtattct
     9601 cataaggtca ttttcagggc aatgataagg cttagtgatc gaaatgatgc tattgatgca
     9661 acaacggtaa ggacgattct tgatgatcaa ggggaccttc aacatattgg tggcttgtct
     9721 tatattgttg agctggttaa tagtgtacct accagtgcca atgcagaata ctatgctaaa
     9781 atagtagctg aaaaggctat gctacgcgat atcatcaata ggttgacaga gactgtaaac
     9841 ttagcctatg aaggagcatc tgactcggag gatattattg caagtgctga gaaggccttg
     9901 gttgatatca gtgagcatag caatcgcagt ggctttcgta agatctcaga cgttttaaag
     9961 attaattatg aaaatcttga ggttcgttct aagcagacat cagacgttac aggtttacca
    10021 acgggcttta gggatcttga caagattaca acaggtttac acccagatca actgattatt
    10081 ttagcagctc gtcctgcagt cggtaagaca gcctttgtct taaacattgc tcaaaatgtt
    10141 ggtacaaagc aaaagagagc agttgccatt ttctccttag aaatgggagc tgaaagcctt
    10201 gttgatcgta tgctggccgc tgagggaatg gtcaattcac atagcttgag gactggtcag
    10261 ttgactgatc aggactggaa taatgtgacc attgcccaag gagccttggc agaagcacct
    10321 atctatattg atgatacacc tggcattaag attactgaga tcagagcaag ggcacgtaaa
    10381 ttgtctcagg aggttgaggg aggcttaggg ctaattgtca ttgattacct ccaactgatc
    10441 actggtacaa gacctgaaaa tcgtcagcaa gaggtttctg atatttcaag gcagctaaag
    10501 attttagcta aggaattaaa agtgcctgtt attgctttga gtcagctttc tcgtggtgtt
    10561 gagcagaggc aggacaagcg tccagttttg tctgatattc gtgagtctgg ctctatcgag
    10621 caggatgcgg atattgttgc atttttgtac cgagatgatt attatcgtaa agaaagcgac
    10681 agcacagaag aggctcttga ggataataca attgaggtga ttcttgagaa aaatagggca
    10741 ggtgcgcgtg ggacagttaa gctgatgttt caaaaggaat acaataaatt ttcgacaata
    10801 gctcaatttg aggaaagata agaaagaggg aaagagaatg agtgatgcat ttacagatgt
    10861 tgccaaaatg aaaaaaataa aggaagacat taaggctcat gaaggtcagt tggttgagtt
    10921 aacacttgaa aatggtcgta agcgtgaaaa aaataaggtt ggcagattga tagaggttta
    10981 cccttcttta tttatcattg agtatcaggg gaacccagat gcttcagggg aagcgaataa
    11041 ttcttatgtt gagtcttata cctattcaga tattttgacg gaaaaaacac tgattcgtta
    11101 ttttgattga aaaatcaatg cccatttagg gctttttctt tacactttgt tgacagctgt
    11161 gtaaagatat gaatcaattt gaagccttga agaacttatt agcaaatgaa tgaagcccgg
    11221 actaataata gggactagct ttcttgaaaa gcagttactc tgagactctc ggtattagat
    11281 atcaaaacat aatatgctat tttcaaagaa tttcctatcg gtattaaaaa gccttgttta
    11341 ctcgggaagt gttgtgtaaa agcttgtttg ccatatgatt aacatcatct ttgagcttac
    11401 agctaaccat ttttgatgat atgatattaa aaatgtaaaa aaaacttgaa tcaatacctt
    11461 tttcatgtta caattagttt tgtgtgaaat aacagcagaa aaatatgaag ctcgtcaaca
    11521 ggcggttaac taaattgagt aacctttgct gtttaggcga aaacctcctg cacgaatcag
    11581 gatttttcaa acagttattt cctcgttata ttttttagag gaggacatga tacatgtcac
    11641 gttatactgg tccatcatgg aaacaatcac gtcgtcttgg cttgtcattg acaggcacag
    11701 gtaaggaatt ggcacgtcgt aactacgtac ctggtcagca tggccctaac aaccgtagca
    11761 agctttcaga atatggcttg caacttgctg agaagcaaaa gcttcgcttt tcatatggta
    11821 tgggggaaaa acaattccgt aacctattcg tacaagctac aaaaatcaaa gaaggaactc
    11881 ttggtttcaa cttcatgctt cttttagagc gtcgtcttga caatgtggtt taccgcttag
    11941 gtcttgcaac tactcgtcgt caagcacgtc agtttgttaa ccatggtcat attcttgttg
    12001 atggtaagcg tgttgatatc ccatcattcc gcgttgagat tggccaagtc atctctgttc
    12061 gtgaaaaatc aatgaaggtt cctgcaatcc ttgaggcagt tgaagcaact cttggacgtc
    12121 cagcttttgt ttcatttgac gctgaaaagc ttgaaggatc attaactcgc ctcccagagc
    12181 gcgacgaaat taacccagaa atcaatgaag cacttgtcgt tgaattctac aacaaaatgc
    12241 tttaagataa gactttatat tataagaagc ccacaacagt gggctttttt ggttgagcgg
    12301 ttagctgatt tatgtaccga ccccaaaggt tagaccaaaa gtctaacgat tggaggtcgg
    12361 tattgttagg cataaagatc attataaact cagtaagaaa tagtttacaa agttgttttt
    12421 tggtactgga tttgacatca ttagtgcagg actatgtttt agatagcatt tttaagacga
    12481 aacgagtcat ttcctgaggg gattcttttt ttcctttagc aatccagctt tggcagacac
    12541 cgaaaaaggc atgtgctagg tagatgcttc gatattcctt ttcggttggg gacaagatgt
    12601 ccttactgaa cttgtcctga agatcggtag tgatcaacag acgaaccttg ttaatgataa
    12661 agctttggat ttctcgggta ccattggagg atagcagagc agatagtagt tgctctcgct
    12721 tgagaaattc aaatacttct aaaaaagcat gctccttgtt ttggtattct ttttcaaaaa
    12781 tgtattctaa tttgtgaaaa aaggtttgtt gatagtaatc aatcatctca tatttgtctt
    12841 tatagtgagt ataaaagcta gaacgactaa tgcctgccat tttagcaagc tgaacggttg
    12901 ttacatcatc gaagctttcg gtttttagta agctcaccat tgcattaaga atggccttct
    12961 tggtttgctg cttgcggcta tccatcatta tctccttttg aacacttgta gacattatgt
    13021 ctaaaaaatt tattttttcc ttgtaaaatg tcactttatt tgtataatat attttatcat
    13081 aatttttgaa cagtatgtct atttggagaa aaaataatgc tagaaggatt aaaagcaata
    13141 atcaaaaatc gtaagctagt agtgacaatg attggggttg ctctagtacc agctctctat
    13201 aatttgtcct ttttagggtc catgtgggat ccttatggtc gggttgatca gttgcctgta
    13261 gcagttgtga atcaggataa gcctgcttac ttgaataaca agagactgac tattggtaac
    13321 gatatggtag acaatatgtc taaaaataag gaattggatt atcattttgt ggctgcagat
    13381 accgcacaaa agggcttgga aaagggtcgt tattatatga cgattacgtt gccaaaggat
    13441 ttgtcacaaa aggccactac gctattagat cagcagccag agaagctgat tgttagctat
    13501 caaactagta agggccatag ctttatcgct tctaaaatgg gtgaatctgc tatgaatcac
    13561 ttgagagagg ctgtttctaa aaatataagg aagacctata tcacctccgt ttttaagagc
    13621 atgcatcagc tccaatctgg tctaaaggaa gcttcaaatg gcggtcagca attagccgct
    13681 ggcttagtaa ttgctagggc aagtagtcag ctaatgtcaa ggcatttgaa caccttgtct
    13741 gaatcaagtg ctcgcttgtc tcaaggagcg ggtaatctat ctagtggtat agctgcctat
    13801 acagccggtg ttggtcagct tgataccgcg ggcttaggac agctagcagc tgatatgcca
    13861 gcgtatctag atggtgtttc tcggttatcc aagggtgcta atcagttaaa tgctggcttg
    13921 acccaattgg ctctaggaag tgatctgtct caagacaaac aagctaatat tcaagcttta
    13981 atggctagcc taccaaagct taatcaggct atccagcagc taaagaccaa tctttccttg
    14041 tctttggcac caaatgtgga ctcaggagcc attgctaagc atttagccga tatgacgcgt
    14101 ttagtgcagg agcttgtggt agatgatact gctgacaaga acaatcagct agccgctcta
    14161 caagctacag ctacctatca aggtctcaac tctgagcagc aggaggagct gagctcagct
    14221 atttccaata cttcaactaa agtaacaata tcagcaaagg ctatgttgac atcactgcaa
    14281 gccatgtctg aggagctaga ggctatgtca acaagtgctg gtgtagctga tcaactgagg
    14341 gactttaaag cacttgttaa tcagctggct tatcaagctg atcaaatcct acctagcaca
    14401 ggcaaggcat tgtcagagct ttcaactggt ttaagggctg ttcactcagc gacaacagcc
    14461 cagctcttat caggtagtca agctcttgct ggcggcttta atcaattgac agctaagaat
    14521 gaagctctta cagcaggcct gtctactctt gctacagggg caacagctct taaccatcaa
    14581 tccagtcaat tattagcagg tggacagcag cttacagtag gcgctaatca gctagctttt
    14641 ggagccaatc agctctcctc tggcagctct cagttgacag atggcttgac aactctgtca
    14701 acaggtctgt caagcttaac gacctcacta tcaaaagctt ctgaccagct ttcaatggct
    14761 tgggtagagg accagaatgc tgatatggta tctgatccag tagcgttatc agagaaggac
    14821 aaggataagg ttaggaccaa tggtattggc atggctcctt atatgattgc tgtgtctcta
    14881 atggtagttg ccttgtctac aaatattatt tttgcagagg ccttatctgg taagccgatt
    14941 aaagatagat gggattgggc aaagcaaaaa ttactgatca atggcatgat ttcgaccgtt
    15001 ggctctgtta ttctttacgc tgcacttcaa ctgctgggct ttgaagctaa tgacggtatc
    15061 aagaccttag gctttattat gctgagtgga tgggccttga tggctttagt gactgcattg
    15121 gtcagctggg atgctcgata tggtgccttt gcttcgttaa ttatgctgtt gctacaggtt
    15181 ggtgctgcgg gtggttctta tcctattgag ttgagtggtc agatcttcca gattctccat
    15241 ccttatcttc caatgtctta tattgtctct ggccttcgtc agacaatatc attaactgcc
    15301 cagataggtt tagagacgag tgtattagtt ggctttttgt taagctttat ggctatagga
    15361 gtgctgattt atcgtccaaa ggacaagcaa tcgtcctaga taatagctga gataacaggt
    15421 tatcgttaaa cagtagatat aataaaaaag cttctagaaa ttgtggttta agctctttct
    15481 agaagctttt tttatggttg gtttagctta cggagataag accattatta ttggaaatgg
    15541 taagctgtgc tttaaagggt gtttgacgac ctgcttcttg actaatcgtt acaaatccat
    15601 tattatttga agcctttacg tcatagtaga tgaggttttc tctaggacaa ttgatgtcaa
    15661 tgattccatt cttattgatg atagtgatgt cattggaaaa ggacagctgc tgccctatga
    15721 tattaccgtt tttgttttca atgaaggttt ctgttagctg acttgcttct aatctgatgt
    15781 ttccattgtt attgttcagc tggcaattta ttagggtgct attgtcacag ctgaggttag
    15841 catttttggc ttgacattta ctagactgga tattgcaatg ctctaaaata atgttcccat
    15901 ttttgctgct taggttgaca gtgctatctg ataaatgact gatagaaatc gttccattgt
    15961 aagtgttaga gacaatgcta tcacaatgta tatgccttat ggtgacatcg ttgttgtcac
    16021 tttctccaga gatttttttc aggtggtggt tgacaggtag tgtcaaggta atgggttgat
    16081 attttgcaag ccagcggtct aggaaatgaa agccatactg tattgtttgt actgctgagt
    16141 cttcaatgat attgagcatg ccgtcactat cttggcttat tgtgatgcga ttatcatcgt
    16201 atgaaatagt agggtaagga atgtcagcag tttcaatggt taaatcatgg ttaagcagac
    16261 tatagcgaat gtcaactatt ggctcaagct tttgtgagct tgcttctgac tttgttttgt
    16321 tgtcaacttc ccaattcgtc cagtcatctt cgtctgtttt ttcggggaga tctaaggctt
    16381 ttaatagctc cttggcaatg tcctctggat ttcccagttc tttaagaata gcttgttcat
    16441 ggtcaggacc agcctcgtca aaatactctg taaaatggtc aatgatttct tggtaatcct
    16501 tttgaggtaa atggttgatc tgctgcttta gcttgtctag aaaatcttgt ttagtcatta
    16561 tgatatcctc ccttgattaa tgaattgata ggtcgctttg attgacagta ttggctatgt
    16621 cagagtgaaa tgaagtagct cctgttgctg cgtctgtgtt aagcttggcg tttgaaaaac
    16681 gagagctgag cttgatgttg cctcttgttg tgacatgata agcaatatct cttggatttg
    16741 ctaatgtggt attgatatta atatcgccgc cattaattgt gtttttctcc ttgattgtga
    16801 catgatttat agcaagctcg gaggggtctg tatagtcata gtcgttttct tcttttgtat
    16861 cagctacagt gatagaagag tctttgatac tgccgtcgtt aagttctagc tgacttgagt
    16921 tctcagcagc ttcataataa tctgctttag gtaattttcg taggtatttg tctagctctg
    16981 ctaggtattc atctcttgtc atgccttaat ctcccttcaa taatgccatc tagggtggcc
    17041 ttgtagcttt gccattcttc ctttaagaaa atcagctgct tttcgccttt ggctgtaatg
    17101 gtgtaatagt tacgcttgcg accttgatgt tcctgactat aggtagttaa atagtctgat
    17161 ttctctagct tttttaaaat agggtatagg gttgattccc tgatattagc gacaagctta
    17221 atggtttggc tgatatcata accataggaa tcatgcttgt cgacaataga taaaatcaaa
    17281 aattcaatca aggtagcaga tactggaaaa tacatctggt tactcccttc ctgcctcgta
    17341 tttatatata attattttat atattaag
//
LOCUS       DARYXW010000043        17202 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.043, whole genome shotgun sequence.
ACCESSION   DARYXW010000043 DARYXW010000000
VERSION     DARYXW010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17202)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17202)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17202
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.043"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            515..1546
                     /locus_tag="TV191_001153"
     CDS             515..1546
                     /locus_tag="TV191_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1507672.1"
                     /translation="MTTKEKQTKLMRRYGIFSVVVALTALAGLGAANEVKATAKKSLN
                     ELPNPVEIIQYNSTRTTDREARKYLNQLYEFLKPYLGSLEEEAQKGGPQGPVGPAGPR
                     GERGEPGPKGDRGPEGQRGEQGPAGPIGPQGPRGDKGETGEIGPRGEQGPTGPTGKPG
                     ERGPKGDRGERGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGE
                     KGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQSQRGEKGEQGKDTKPSAPKAPEQSPAP
                     QVPKTSEQQSASPKVPAPKSAPSKSAAPAAQKGILPATGETNHPFFTLAALGVIASAG
                     LLTLKRKNN"
     gene            2040..2564
                     /locus_tag="TV191_001154"
     CDS             2040..2564
                     /locus_tag="TV191_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HEL1507673.1"
                     /translation="MVEYWDIYTMNRLKTGRLMERGAAFVEGAYHLVVHACVFNDKGE
                     MLIQQRQKDKEGWPSYWDITVGGSALAGETSQEAVMRELKEELGLTLDLAGVRPHFSI
                     TFDNGFDDTFLILQAVDVRKLVLQTEEVQAVRWASRDEILAMIDAGIFIPYFKSKIDM
                     CFELVGQYGAIKWS"
     gene            2779..3630
                     /locus_tag="TV191_001155"
     CDS             2779..3630
                     /locus_tag="TV191_001155"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HEL1507674.1"
                     /translation="MTAIIERAPAKINLGLDIQGKRPDGYHDLSMVLVSVDLCDYITV
                     DHLEEDRILLTSNCPRLPINEHNDVYKAAYLLKERFQISTGVSIFLDKRVPVCAGMGG
                     GSSDAAAAIRALNQLWQLKLSPRQMIDIGMQIGSDVPYCLFAGCAQVTGKGEVVKPIN
                     GRLSSWVVLVKPEFGISTRTIFWDIDCETISRVPIEDLVSAIEAGDYQRLLATMGNSL
                     EDISIAKRPFIQKVKDKMLQSGADIALMTGSGPTVFALCQTEKQANRVVNSLKGFCKE
                     VYKVRTL"
     gene            3700..4143
                     /locus_tag="TV191_001156"
     CDS             3700..4143
                     /locus_tag="TV191_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent MarR family transcriptional
                     regulator"
                     /protein_id="HEL1507675.1"
                     /translation="MTILEKKLDNLVNRILLKAENQHELLFGACQSDVKLTNTQEHIL
                     MLLSQEKLTNTDLAKRLNISQAAVTKAIKGLIKQEMLAGTKDTVDARVTYFELTDLAR
                     PIAKEHTHHHDKTLAVYHRLLAHFSAEEQVIVEKFITAFAEELEG"
     gene            4146..4865
                     /locus_tag="TV191_001157"
     CDS             4146..4865
                     /locus_tag="TV191_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEL1507676.1"
                     /translation="MRYISVENLSFQYDSEPVLEGISYHLDSGEFVTLTGENGAAKST
                     LIKATLGILKPRAGQVTIAKQNIHGKKLRIAYLPQQVASFNAGFPSTVYEFVKSGRYP
                     RSGWFTRLSKHDEEHVRTSLESVGMWDSRHKRIGSLSGGQKQRVVIARMFASDPDIFV
                     LDEPTTGMDSGTTDTFYELMHHSAHRHGKAVLMITHDPEEVKAYADRNIHLIRNQRLP
                     WRCFNIHDAEADESKGGSFHA"
     gene            4858..5667
                     /locus_tag="TV191_001158"
     CDS             4858..5667
                     /locus_tag="TV191_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEL1507677.1"
                     /translation="MLEILSYDFMQRAVMAVVAISIFAPILGIFLILRRQSLLSDTLS
                     HVSLAGVAFGVVLGVSPTFTTIIVVVLAAILLEYLRVVYKHYMEISTAILMSLGLAIS
                     LIIMSKSTSSSSMSLEQYLFGSIITISTEQVAALFVIALIILALTILFIRPMYILTFD
                     EDTAYVDGLPVRVMSVLFNIVTGVAIALTIPAAGALLVSTIMVLPASIAMRLGKNFKS
                     VIFLGIMIGFTGMLSGIFLSYFWETPASATITMIFIAIFLVVNLLSFIRQK"
     gene            complement(5702..6958)
                     /locus_tag="TV191_001159"
     CDS             complement(5702..6958)
                     /locus_tag="TV191_001159"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEL1507678.1"
                     /translation="MNIFEELKARGLVFQTTDEEALVKALTEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERILQTKETVLDWSQKIK
                     EQLSCFLDFDNGENKAELVNNYDWFSQISFIDFLRDVGKHFTINYMMSKDSVKKRIET
                     GISYTEFAYQVMQGYDFYELNAKHNVTLQIGGSDQWGNMTAGTELLRKKADKTGHVMT
                     VPLITDATGKKFGKSEGNAIWLDAKKTSPYEMYQFWLNVMDDDAVRFLKIFTFLSLDE
                     IAAIEEQFNAARHERLAQKTLAREVVTLVHGEAAYQQALNITEQLFAGAIKNLSAAEL
                     KQGLSNVPNYQVQAEDSLNIVDMLVTAGISPSKRQAHEDLQNGAIYLNGERLQDLDYS
                     LSTADRIDNQLTVIRRGKKKYAVLTY"
     gene            7063..9363
                     /locus_tag="TV191_001160"
     CDS             7063..9363
                     /locus_tag="TV191_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014611927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL1507679.1"
                     /translation="MVKWKKNQTSKNHQRLELVDFGTVFLRTLKFMSSFFYVAVFLFG
                     MLGAGMAFGYLASQIDSVKIPSKESLVKQVESLTMMSQITYSDNSLISGIDTDLLRTP
                     VANDAISDNIKKAIVSTEDDNFQRHNGIVPKAIFRATLASVLGFGESSGGSTLTQQLI
                     KQQVLGDDPTFRRKSKEIIYALALERYMSKDDILSHYLNVSPFGRNNKGQNIAGVEEA
                     ARGIFGVSAKDLTVPQAAFLAGLPQSPIVYSPYLPTGQLKSADDMAYGIKRQQNVLYN
                     MYRTGVLTEKEYRDYKAYPISNDFIKPETVTANTHDYLYYSVLAEAQKAMYSYLIKRD
                     KVPAKDLKNDETKAAYEERALTELQHGGYTVKTTINKPIHQVMQKAAAQFGGLLDDGT
                     GTVQMGNVLTDNATGAVLGFIGGRDYAQNQNNHAFNTVRSPGSSIKPIIAYGPAIDQG
                     LMGSASVLSNYPTTYSSGQKIMHVDSEGTAMMPLQEALNTSWNIPAFWTQKLLRDKGV
                     DVENYMSKMGYRIADYSIESLPLGGGIETSVAQQTNAYQMIANNGLYQKQYMVASITA
                     SDGSVVYQHEAKPVRIFSAPTATILQELLRGPISSGATTTFKSRLAGINPSLAGADWI
                     GKTGTTENYTDVWLVLATPRVTLGGWAGHDDNTSLAPLTGYNNNSNYMAYLVNAISQA
                     DPNLFGLGQRFSLDPGVIKASVLKATGLKPGTVTINGQTISIGGELTTSLWAQKGPGA
                     TTYRFAIGGTDADYQKAWGGFSGRRN"
     gene            9625..13191
                     /gene="rpoB"
                     /locus_tag="TV191_001161"
     CDS             9625..13191
                     /gene="rpoB"
                     /locus_tag="TV191_001161"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEL1507680.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFQDFLDSG
                     LKEVFEDVLPISNFTDTMELEFVGYEFKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELETDSKDIAYTRIDRTRKIPFTTLVRALGFSGDDEIIDIFGDSELVR
                     NTIEKDIHKNQSDSRTDEALKEIYERLRPGEPKTADSSRSLLTARFFDARRYDLAAVG
                     RYKINKKLNIKTRLLNQIIAENLIDSETGEILVEAGTEMTRSVIESIEEQLDGDLNKF
                     VYTPNDYAVVTEPVILQKFKVVSPVDPDRVVTIVGNANPDDKVRALTPADILAEMSYF
                     LNLAEGLGKVDDIDHLGNRRIRAVGELLANQFRIGLARMERNVRERMSVQDNDVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSFGHLNKYGFIQTPYRKVDRVIGRVTNEIV
                     WLTADEEDEFTVAQANSKLNPDGTFAEEIVMGRHQGNNQEFPASQVDFVDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLIDPKAPYVGTGMEYQAAHDSGAAVIAQH
                     NGKVVFSDAERVEVRREDGSLDVYHITKFRRSNSGTAYNQRTLVKIGDIVEKGDFIAD
                     GPSMEKGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKEDVYTSVHLEEFESETRDT
                     KLGPEEITREVPNVGEEALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGGDGIVRDVKIFTRANGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARNLGIHIATPVFDGATSEDLWETVREAGMDSDAKTVLYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDVNGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDN
                     EVELRDLDEGEDDDVMHVDDLEKAREKQAQETQDIAESTEDN"
     gene            13282..16917
                     /gene="rpoC"
                     /locus_tag="TV191_001162"
     CDS             13282..16917
                     /gene="rpoC"
                     /locus_tag="TV191_001162"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEL1507681.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRAKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEPKSLLTEREYREKIQ
                     EYGHGSFIAKMGAEAIQDLLKRVDLVTEIAELKEELKTATGQKRIKAVRRLDVLDAFH
                     KSGNKPEWMILNILPVIPPDLRPMVQLDGGRFAASDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVIREIVAREFAGNVKAAKRMVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARLLMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEDA
                     GREGEGMVFKDKDEAVMAYRNGYVHLHSRVGIAVDSMPSKLWKDSQRHKIMVTTVGKI
                     LFNDIMPEDLPYLQEPNNANLTEGTPDKYFLKPGQNIQEVIDSLPINVPFKKKNLGNI
                     IAETFKRFRTTETSAFLDRLKDLGYYHSTLAGLTVGIADIPVIDNKAEIIEAAHHRVE
                     EINKAFRRGLMTDDDRYVAVTTTWREAKEALEKRLIETQDPKNPIVMMMDSGARGNIS
                     NFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADS
                     GYLTRRLVDVAQDVIIREDDCGTDRGLLIRAITDGKEVTETLEERLQGRYTRKSVKHP
                     ETGEVLIGADQLITEDMARKIVDAGVEEVTIRSVFTCATRHGVCRHCYGINLATGDAV
                     EVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRIQEIFEARNPKGEAV
                     ITEVKGTVIEIEEDASTRTKKVYVQGKTGMGEYVVPFTARMKVEVGDEVNRGAALTEG
                     SIQPKHLLEVRDTLSVETYLLAEVQKVYRSQGVEIGDKHVEVMVRQMLRKVRVMDPGD
                     TDLLPGTLMDIADFTDANKEIVISGGIPATSRPVLMGITKASLETNSFLSAASFQETT
                     RVLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMVRYRNIEPQAINEVEVIEEAEATE
                     EPAIIKE"
     gene            complement(17009..17202)
                     /locus_tag="TV191_001163"
                     /pseudo
     CDS             complement(17009..17202)
                     /locus_tag="TV191_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679490.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         4714 a         3320 c         4250 g         4918 t
ORIGIN      
        1 tgataaaaaa tcactgaatg atagctgtgt ttgatgtttg caacatttta aaatatcttt
       61 gcaaaaatca tacctagaca catacaatcc cacataagtt ttaaaagcat tcaattgcct
      121 tttaagatct ttatgagtca tgtttgtaaa gatatcctct tgcaacagat ctcttaatct
      181 ctaattgtat ccaataagaa gcagctttgt caatacggaa gccgaatagt ctttttgcct
      241 ttccttgtca gctgggcaat catgagggct ttgtgctttg atcttttgca tctataaaag
      301 ggtgaatcta ttgatgaggt gttatcggta gtggggccta ctgatgtcaa taactgacgt
      361 cagataatta cctctttaat tagaaaaaaa aaaaaaacga aactacggag agaacctaat
      421 aactggctat ttcttgctat aagccagcgt gttaaaatct tctttgggag aaaatttaga
      481 aaaaaataat atttctatca ctaaggagag aaagatgaca actaaagaaa aacaaacaaa
      541 actaatgcgc aggtatggca ttttctcggt agtcgttgcc ctaacagctc tagcaggtct
      601 aggagcagct aatgaagtta aggcaactgc taaaaaatct ttaaatgagt tacctaatcc
      661 agtagaaatt attcaatata attcaacaag aactactgat agagaagcta gaaagtatct
      721 taatcaatta tatgagtttt tgaaacctta tttaggaagt ttagaagaag aagctcaaaa
      781 aggagggcca caaggacctg tgggacctgc tggtcctaga ggtgaacgcg gagaaccagg
      841 acctaaagga gaccgaggtc ctgagggcca aagaggtgag caaggcccag cggggcctat
      901 tggaccccaa gggcctcgtg gtgacaaggg tgaaactgga gaaattggac ctaggggaga
      961 acaaggtccg accggtccta ctggtaagcc aggagagcgt ggccctaagg gtgacagagg
     1021 cgaacgcggc gaaaaaggcg agcaaggcca gcgtggcgaa aaaggcgagc aaggccaacg
     1081 tggcgaaaaa ggtgaacaag gccaacgcgg tgaaaagggc gagcaaggcc aacgtggcga
     1141 aaaaggtgaa caaggccaac gcggtgaaaa gggcgagcaa ggccaacgtg gcgaaaaagg
     1201 cgagcaaggc caacgtggcg aaaaaggtga acaaggccaa cgcggtgaaa aaggtgaaca
     1261 aagccaacgc ggtgaaaagg gcgagcaagg aaaggatacc aaaccatcag ctccaaaggc
     1321 cccggagcaa tctcctgctc cacaggtacc aaagacttca gagcagcagt cagctagtcc
     1381 taaggtacca gcgcctaagt cagcaccaag caaatcagcg gctccagcag ctcaaaaggg
     1441 tatattacca gctacaggag agacaaatca cccattcttc acccttgcag ctctcggcgt
     1501 cattgccagc gcaggcctgc taactctaaa aagaaaaaac aactaaatta gcttttgcaa
     1561 ctttctccta ctaaatgata gcctttagct tgaaggcgat tgattagttt aaaagctgat
     1621 atgagcacta gagaggccct aatggggtct ctttttgctt gcagcagtag atgttttgtc
     1681 ttcctctttc atggggtgat gtagttggtg tgcttttggg ttgagccttt aaggtttttt
     1741 gtaactaata tgatgaggca agtcagctgt gtgtatcacc atatcgttaa ctgagtaaga
     1801 cgcttgggga tcttaactac cagtttgtta gcgtggtgag ctttttgata cgtctcggga
     1861 aaacagatct ttttgtccat tttctatgcg aggcatttta aggtagggaa ttgtagaaaa
     1921 aagaattaag ctaggttggt aattgttgtt ttgtctggac ctggttgttt tggatatgct
     1981 tattgtgata tgattaatat actggatctg gtaatagctg tatcaggagg tgtgtttgta
     2041 tggttgagta ttgggacatt tatacgatga atcgtcttaa gactggtaga ctcatggagc
     2101 gtggagctgc ttttgtagag ggtgcttatc atttagtggt tcacgcctgt gtctttaatg
     2161 acaagggaga aatgctgatt cagcagcggc aaaaggataa agagggttgg cccagctatt
     2221 gggatataac ggtaggcggc agcgctcttg caggtgagac gtcacaagag gcagtgatga
     2281 gagaactgaa ggaggagcta ggacttactc ttgatttagc tggtgtaagg cctcattttt
     2341 caattacctt tgataatggc tttgacgata cttttttgat tttgcaggct gttgatgtaa
     2401 ggaagctagt tcttcagaca gaggaggtac aggctgttcg atgggctagt cgtgatgaga
     2461 ttttagccat gattgatgct ggtattttta ttccctactt taagagcaag attgatatgt
     2521 gctttgagtt agtggggcaa tatggagcga tcaagtggtc atagagactg ctgctgtctt
     2581 agctttgctt gctatgctag tagttgtcgt tttttggctg ctgatctggt gaagcctcac
     2641 gctagtaggg acaaatggtt ggctgttttg atacaaacac gctgtctatg catcattaga
     2701 tactaactgt atttatttga atttttcatg aagattgtgt atatttgata ctataatgac
     2761 atcaaataaa ggagtattat gactgcaatc attgagagag ctcctgcaaa aataaatcta
     2821 ggcttagata ttcaaggcaa gcgaccagat ggctatcatg acctatctat ggttctagtt
     2881 agtgtagatc tttgtgatta tattacagtg gatcatttag aggaggatag gattttattg
     2941 acctctaatt gccctagatt gcctattaat gagcacaatg acgtttacaa ggcggcttat
     3001 ttgctgaaag agcgatttca aatctcaaca ggtgtctcta ttttcttgga taagagggta
     3061 cctgtttgtg ctggtatggg aggtggctca agtgatgcgg ctgcagcaat cagagcattg
     3121 aatcagctgt ggcagctaaa gcttagtccc cgtcagatga ttgacattgg catgcagatt
     3181 ggtagcgatg tgccttattg tctttttgca ggctgcgccc aagtgactgg caaaggcgag
     3241 gtggttaagc caatcaatgg ccgcttgtcc tcttgggtgg ttctagtgaa gccagaattt
     3301 ggcatttcta ctagaacgat tttttgggat attgattgtg agacgatatc tcgagtgccg
     3361 attgaggatc tggtttcagc cattgaggca ggtgattatc agcgcttgct tgcaacgatg
     3421 ggaaattcct tagaggatat ttccattgct aaacggccgt ttattcaaaa ggttaaggat
     3481 aaaatgctgc agtcaggagc agacattgcc ctgatgacag gaagtggtcc aacggtattt
     3541 gccctatgtc aaacagaaaa gcaggccaat cgtgtggtga atagcctgaa aggcttttgt
     3601 aaggaagtct acaaggttag aacgctgtag atcagccttg aagttgcgtc ttttggggcg
     3661 tcatgttata attaactggt taatgaggag agggaaatca tgacaatttt agaaaaaaag
     3721 cttgataatt tggttaatcg tattttgtta aaggctgaaa atcagcatga gctgctcttt
     3781 ggggcttgtc agagtgatgt caaattaaca aatactcagg agcatatttt gatgcttttg
     3841 tcacaggaaa agctaaccaa tacagatttg gcaaaaaggc taaatatcag tcaagcagca
     3901 gtaactaaag cgattaaagg cttgatcaag caagaaatgc tagcaggaac aaaggatacc
     3961 gttgatgctc gagtaaccta ttttgaactg actgatctag caaggccaat cgctaaggag
     4021 catacacatc atcacgataa aacactagct gtttatcatc gtttgttggc acatttttct
     4081 gcggaggagc aggtgattgt tgaaaaattt atcactgctt ttgcggagga gttagaaggg
     4141 taataatgag atacatatcg gtggaaaatc tctcgttcca gtatgacagt gagcctgttt
     4201 tagagggaat cagctatcat ttggatagtg gagaatttgt cacattgact ggtgaaaatg
     4261 gtgctgccaa gtcaaccctg atcaaggcga ccttggggat tttaaagcca agggctgggc
     4321 aggtgactat agctaaacag aacattcatg ggaaaaagct gagaattgct tacttgccac
     4381 agcaggttgc cagctttaat gcaggctttc cgtcgactgt ttatgaattt gttaaatcag
     4441 gcagatatcc tagaagtggt tggtttacca gactaagtaa gcacgatgag gagcatgttc
     4501 ggacaagctt ggagtctgtt ggcatgtggg atagtcggca taagagaata gggagtctat
     4561 caggtggtca aaagcagcgt gtggttattg cgcgtatgtt tgcttctgac cccgatattt
     4621 ttgtgcttga tgagccgacc acaggaatgg atagtggaac aacagatact ttttatgagt
     4681 tgatgcacca cagcgctcat agacatggta aggctgtttt gatgattaca catgacccag
     4741 aggaggtcaa ggcttatgct gatcgcaata ttcatttgat tagaaatcaa cggcttcctt
     4801 ggcgttgctt caacattcat gatgctgagg ctgatgagag caaaggaggg tcattccatg
     4861 cttgagattt tatcttatga ttttatgcag cgtgctgtta tggctgttgt ggcgatcagt
     4921 atctttgctc cgattttggg tatctttttg attttgcgtc gtcaaagctt gttgagtgat
     4981 acgcttagcc acgtttctct ggctggtgtg gcctttggtg ttgttcttgg tgtttcgcca
     5041 accttcacaa cgattattgt ggtggtgcta gctgccatct tgctagaata tcttagggtg
     5101 gtttataagc actatatgga gatttcgaca gctatcctaa tgtccttggg gctggctatt
     5161 tccttgatta tcatgagtaa gtcaactagc tcttctagta tgagcttgga gcaatacctt
     5221 tttggctcta tcattactat tagtacggag caggttgctg ccttatttgt cattgctttg
     5281 attattttag ccttgacgat attatttatt cgtccaatgt atatcttgac cttcgatgag
     5341 gacacagcct acgtcgatgg cttgccggtg cgtgtcatgt ctgtcttgtt taatattgtg
     5401 acaggtgttg ctattgctct aacgatccca gcggcagggg cccttttggt atcaacgatt
     5461 atggttttgc cagcaagtat tgctatgcgg cttgggaaaa actttaaatc agttattttt
     5521 cttgggatta tgattggctt tacaggcatg ctgtctggta ttttcttgtc ctatttttgg
     5581 gaaacgccgg caagtgcgac cattacgatg atttttattg cgatcttcct tgtggttaac
     5641 ctgctgtcct ttatacgtca aaaataatca tccaaagcaa gattttccta gctgtctgtg
     5701 attagtaggt tagtacagcg tattttttct tgccgcggcg aatgacggtc aactgattgt
     5761 caatgcgatc tgctgtagat aagctgtaat ccagatcctg aagtcgttct ccattgaggt
     5821 agatcgcgcc attttgtaaa tcctcatgcg cctgacgttt tgatggtgaa atgcctgctg
     5881 tgactaacat atccacgata tttaggctgt cttctgcttg aacctgatag ttagggacat
     5941 tgcttaagcc ttgcttaagc tcagctgctg aaaggttttt gatagctcct gcaaaaagct
     6001 gttcggtaat attgagggct tgctggtagg ctgcctctcc atgaaccagt gtcaccacct
     6061 cacgcgcaag tgtcttttga gcaaggcgct catggcgtgc tgcgttgaac tgctcctcaa
     6121 tagcagcaat ctcatcaagt gataagaagg tgaagatctt caggaagcgt accgcatcat
     6181 cgtccataac atttaaccag aactggtaca tctcgtaagg agatgttttt ttagcgtcaa
     6241 gccaaatcgc attaccctct gacttgccga attttttacc tgttgcatct gtaatcaatg
     6301 gcactgtcat cacatgtcca gtcttgtcag cttttttgcg gagcaattcg gtacctgctg
     6361 tcatattacc ccactggtca gagccgccga tttgcagtgt cacattgtgc ttagcattta
     6421 gctcgtaaaa atcgtagcct tgcatgacct gatatgcaaa ttcggtgtag gaaattccgg
     6481 tttcgatacg ttttttcact gaatccttgc tcatcatgta attgatagtg aagtgcttgc
     6541 cgacatcacg aaggaagtca ataaagctaa tctgtgagaa ccagtcatag ttgttgacaa
     6601 gctcagcctt gttttcaccg ttgtcaaagt caagaaagca agagagttgt tctttaatct
     6661 tttggctcca atcaagaacg gtttccttgg tttgtaggat acgctcagcg tctttaaagg
     6721 acggatcacc aatcagccca gttgccccac cgacaagagc gtagggcttg tgtcctgcta
     6781 gctgcaagcg acgtgatgtc aaaatggcaa cgagatgacc aagatgcagg ctatcagctg
     6841 ttggatcata gccagtgtaa taggatactt gcccttctgt taatgctttg acaagggctt
     6901 cttcatcggt cgtctgaaag accaagccac gagctttgag ttcttcaaaa atattcatag
     6961 gctttctcca ttttctttat gatttccgaa tcattatatc aaaaatgact gtggctgtgc
     7021 aagcttaatc aaagtttggt ataatgaaga ttgaggtacg ttatggtgaa atggaaaaag
     7081 aatcaaacaa gcaaaaatca tcagcgatta gaattagttg attttggaac ggtctttttg
     7141 cgcacattaa aattcatgtc gagctttttt tatgtagctg tctttttatt tggcatgctg
     7201 ggtgctggta tggcctttgg ctatttagcc agtcaaattg actcggtaaa aattccaagt
     7261 aaggaaagtc ttgtcaagca ggttgaatca ttgaccatga tgtcacagat tacctattca
     7321 gataatagct tgatttcagg cattgatacg gatctgctta ggacaccggt tgctaatgat
     7381 gcgatttcag acaatatcaa aaaggctatt gtctcaactg aggacgacaa ctttcagcgc
     7441 cataatggca ttgtgccaaa ggcgattttt cgtgcgactc tggcctctgt tttgggcttt
     7501 ggggagtcaa gtggtggctc tacgctgaca cagcagttga ttaagcagca agtcttgggc
     7561 gatgatccga cctttaggcg aaaatcaaag gaaattatct atgcactggc cttagagcgt
     7621 tacatgtcaa aggacgatat tttatcacat tatttaaacg tgtcgccttt tggtcgtaat
     7681 aataagggac aaaacattgc aggtgtggag gaggctgcgc gtggcatttt tggagtctct
     7741 gccaaggatt tgacggttcc gcaggcggcc tttttggcag ggcttccgca aagcccgatt
     7801 gtttattcgc cgtatttgcc gacagggcag ttaaaatcag ccgatgatat ggcctatggg
     7861 attaagcgcc agcaaaatgt cctctacaat atgtatcgaa caggtgtgct gacagaaaaa
     7921 gaatatcgtg attataaggc atatcctatt agcaatgatt ttatcaaacc tgaaacagtc
     7981 actgccaata ctcatgatta cctctactat tctgtcttgg cagaggcaca aaaggccatg
     8041 tatagctatc tgattaagcg agataaggtg cctgctaaag atttaaaaaa tgatgagact
     8101 aaggctgcct atgaggagcg agccttaact gagctgcagc atggcggcta cactgtcaaa
     8161 acaacaatca ataagccaat ccatcaggtg atgcaaaaag cggcagctca gtttggtggc
     8221 ttgttagatg atggcactgg gacagtgcag atgggcaatg tcctaacgga caatgctaca
     8281 ggtgctgttt tgggctttat tggtgggaga gactatgctc aaaatcaaaa caatcatgcc
     8341 tttaatactg ttcgctctcc aggctctagc attaagccga ttattgctta tggacctgcc
     8401 attgatcagg gattaatggg aagtgctagt gtcctatcca actatccgac gacctattcc
     8461 agcggtcaaa aaatcatgca cgtcgatagt gaaggaacag caatgatgcc cctgcaggag
     8521 gcgcttaata cctcatggaa tattccagcc ttttggactc aaaagctgct gcgtgataag
     8581 ggcgttgatg ttgaaaacta tatgagtaaa atgggatatc ggattgctga ttattccatt
     8641 gaaagtctgc cacttggtgg tgggattgag acctcggtag cccagcagac caatgcttat
     8701 cagatgattg ctaataatgg tctttatcaa aagcaatata tggtggctag tatcacagct
     8761 agtgatggat ccgttgttta tcagcatgag gccaagccgg ttcgtatttt ctcagctccg
     8821 acagcaacga ttttacagga gctcttgaga gggccgattt catctggggc aacaaccact
     8881 tttaaaagcc gattagcagg gatcaaccca agccttgcag gtgctgactg gataggtaaa
     8941 acaggaacaa ccgaaaatta taccgatgtc tggctggtct tagctactcc aagggttact
     9001 ttgggtggtt gggcaggcca tgatgacaat acctcgcttg caccactgac gggatacaat
     9061 aataattcaa attatatggc ttatttggtt aatgccatca gtcaggctga tcccaatctt
     9121 tttggccttg gtcagcggtt ttcactggat cctggtgtta tcaaggcttc tgtcttgaag
     9181 gccactggtc taaagccggg tacagtgacg atcaatggcc aaaccatctc catcggtgga
     9241 gagctaacaa ccagcctttg ggctcaaaag ggacccggag caactaccta taggtttgcc
     9301 attggtggaa cagacgcaga ctatcaaaaa gcctggggag gttttagtgg tagaagaaat
     9361 tagttgtatt ttccagacaa atagtgtata atatctataa ctatttgtcg tctaatctag
     9421 ctgaaatatt gtccagctag aaagaacagc agttaaatca cactgataag gtccgattta
     9481 gctgctcttt ttgtgcctat ttttagataa aaatcaattt tgtaacaaaa atttaaagat
     9541 tctaaaaata ccacttaaga caaatattga tgttgcaatt gtttgcttga tagcaaagct
     9601 taaaaagaaa aaggagctaa aaacttggca ggacatgacg ttcaatacgg gaaacatcgt
     9661 acccgtcgta gtttttcaag aatcaaagag gttcttgatt taccaaattt gattgaaatt
     9721 caaactgatt cattccaaga tttcttagat tcaggcttga aggaagtatt tgaagatgtg
     9781 cttccaatct caaactttac agacacgatg gagcttgagt ttgttggtta cgaatttaag
     9841 gagcctaaat atacccttga agaggctcgt atccatgatg caagctattc tgcaccaatc
     9901 tttgtgacct tccgcctgat taataaggaa actggcgaaa tcaaaacaca agaggtcttt
     9961 tttggtgatt ttccgattat gactgaaatg ggaaccttta tcatcaacgg tggagagcgt
    10021 attattgttt ctcagctggt tcggtctcct ggtgtttatt tcaatgacaa ggttgataaa
    10081 aatggtaagg ttggttatgg ctcaacagtt atccctaatc gtggtgcttg gctagagcta
    10141 gaaactgact caaaggatat tgcttatact cgtattgacc gtacgcgtaa aatcccattt
    10201 acaacgctag tgcgtgcact tggtttttct ggtgatgacg aaattattga tatttttggt
    10261 gatagtgagc ttgttcgcaa taccattgaa aaggatattc ataaaaacca aagcgattca
    10321 cgtacagatg aggctcttaa ggaaatttat gaacgcttaa gaccaggtga gccaaagaca
    10381 gctgatagct cacgcagcct tttgacagct cgtttctttg atgctcgccg ttatgacttg
    10441 gcagcagttg gccgttataa gattaataaa aagctgaaca tcaagacacg tcttttgaat
    10501 caaattattg ctgaaaatct aatagatagt gagactggag agattctggt tgaggctgga
    10561 acagagatga ctcgtagtgt gattgagtca atcgaagagc agcttgatgg ggatttgaac
    10621 aagtttgtct acacaccaaa cgattatgcg gtggtgacag agcctgtgat cctacaaaaa
    10681 ttcaaggtgg tttcaccagt tgatcctgat cgtgtggtga cgatcgttgg taatgctaac
    10741 ccagatgata aggttcgtgc ccttactccg gctgatattt tggctgagat gtcttatttc
    10801 cttaaccttg ctgaaggtct tggaaaggtc gatgacattg accacttagg taatcgtcgt
    10861 atccgtgcag ttggtgaatt gcttgctaac caattccgta ttggtcttgc tcgtatggag
    10921 cgcaatgtcc gcgagcgtat gtctgtacag gataacgatg tgttgactcc acaacagatt
    10981 attaacattc gtcctgtaac ggcggctgtc aaagaattct ttggttcttc acagctatca
    11041 cagttcatgg atcagcacaa cccattgtct gagttgtcgc acaaacgtcg tttgtctgcc
    11101 ttaggacctg gtggtttgac acgtgatcgt gctggctatg aggtgcgtga cgtgcactac
    11161 actcactatg gtcgtatgtg tccgattgaa acacctgaag ggccaaatat cggtttgatt
    11221 aataacctgt cttcatttgg acatctgaac aaatacggct ttattcaaac cccttaccgt
    11281 aaggttgatc gtgtgattgg ccgagtgact aatgagattg tttggctaac tgctgatgaa
    11341 gaggatgagt ttacagtggc tcaggctaat tctaagctca atccagacgg tacctttgct
    11401 gaagagattg tcatgggacg tcaccaaggt aataaccaag agtttcctgc tagtcaggtt
    11461 gactttgttg acgtgtctcc taagcaggta gtcgctgttg cgacagcatg tattcctttc
    11521 cttgaaaacg atgactccaa ccgcgcccta atgggagcta acatgcagcg tcaggctgtg
    11581 ccattgattg atccaaaggc tccttatgtt ggtacgggta tggaatatca agcagctcat
    11641 gattcaggtg ctgcggtaat tgcccagcat aatggtaagg ttgtcttttc agatgctgaa
    11701 agagtagagg tgcgtcgtga ggacggttca cttgatgttt accacatcac aaaattccgc
    11761 cgttcaaact ctggtactgc ctacaaccaa cgaacccttg ttaaaatagg tgatattgtt
    11821 gaaaagggtg actttatcgc tgatggccct tctatggaaa aaggtgagat ggctcttggt
    11881 caaaatccaa tcgttgctta catgacctgg gaagggtaca actttgagga cgcggttatc
    11941 atgagtgagc gtcttgtgaa ggaggacgtt tatacctctg ttcacttgga ggagtttgaa
    12001 tcagaaacac gcgacacaaa gcttggacct gaggaaatca cacgtgaagt gccaaacgtt
    12061 ggtgaagaag ccctcaagga ccttgatgaa atgggtatta tccgtatcgg tgcagaggtc
    12121 aaggaaggcg atattcttgt tggtaaggta actcctaagg gtgaaaaaga cctttctgct
    12181 gaagaacgtc tcctgcatgc tatctttggt gataaatcac gtgaggttcg tgatacctcg
    12241 ttacgtgttc ctcatggtgg tgacgggatt gtacgtgatg tgaagatctt tacacgcgca
    12301 aatggtgatg agcttcaatc aggtgttaat atgctggtgc gtgtttacat tgctcaaaag
    12361 cgtaaaatca aggtcggaga taaaatggcc gggcgtcatg gtaacaaggg tgtcgtctca
    12421 cgtattgtac cggttgagga tatgccatat ctgccagacg gaacccctgt tgacatcatg
    12481 ctgaaccctc ttggggtgcc gtctcgtatg aacattggac aggttatgga gcttcaccta
    12541 ggtatggctg ctcgtaattt gggtatccat atcgcaacac cggtctttga cggagctacg
    12601 tctgaggacc tttgggaaac tgttcgtgaa gcaggtatgg atagcgatgc taagactgtt
    12661 ctttatgatg gccgtactgg tgagccgttt gataatcgtg tgtcagttgg tgtcatgtat
    12721 atgattaagc ttcaccacat ggttgatgat aagcttcacg cgcgttctgt aggaccatac
    12781 tcactggtta cccaacagcc gcttggaggt aaagctcagt ttggtggcca acgttttggt
    12841 gagatggagg tatgggctct tgaggcttat ggtgcttcaa acgttcttca ggaaatcttg
    12901 acctataagt cagacgatgt gaatggtcgc ttgaaagctt atgaggcgat taccaaaggt
    12961 aagccaattc caaagcctgg tgtaccagaa tctttccgcg ttcttgtgaa agaattgcaa
    13021 tcacttggtc ttgatatgcg tgtccttgat gaagacgata atgaagttga gcttcgtgat
    13081 cttgatgaag gcgaagacga tgacgtgatg cacgttgacg atcttgaaaa agcgcgtgaa
    13141 aagcaggctc aggaaactca agatattgct gaatcaactg aagacaacta aatcataaac
    13201 atttgtaaca gaaataatga ctagactagg gctatttgcc ctagctgcta gtaagtcatc
    13261 aaaggcagaa aggtaaaact agtggttgac gtaaatcgtt ttaaaagtat gcaaatcaca
    13321 ttagcttcac caagtaaggt ccgttcatgg tcctatggtg aagttaaaaa acctgaaaca
    13381 atcaactacc gtacattaaa accagaacgt gagggtcttt ttgacgaagt catttttgga
    13441 ccaaccaagg attgggagtg tgcgtgtggc aaatataaac gtattcgcta taagggcatt
    13501 gtctgtgacc gttgtggggt cgaggtaacg cgtgcaaagg ttcgtcgtga acgcatggga
    13561 cacattgagc tgaaggcacc tgtctcacat atctggtatt ttaagggaat cccatctcgt
    13621 atgggcttga ctcttgatat gagtcctcgt gctcttgagg aggtaatcta ttttgcggct
    13681 tatgtggtta ttgatccaaa ggacacaccg cttgagccaa aatcactatt gacagagcgt
    13741 gaatatcgtg aaaaaatcca agaatatgga catggctcat tcattgctaa aatgggggca
    13801 gaggctattc aagacctcct aaagcgtgtt gatttggtca cagaaattgc tgagctaaag
    13861 gaagaattaa aaacagcaac aggccaaaag cgtatcaagg ctgttcgtcg gttagatgtg
    13921 cttgatgcct ttcataaatc aggcaataag ccagaatgga tgatcctgaa catcttgccg
    13981 gtcattccac cagatcttcg tcctatggtg caattggacg gtggccgctt tgcagcctca
    14041 gacttgaatg acctttaccg tcgtgtcatt aaccgtaata atcgtttagc acgtttgttg
    14101 gagcttaatg cgcctggtat cattgtgcaa aatgaaaagc gtatgctgca agaggcggtt
    14161 gatgctttga ttgataatgg tcgtcgtggt cgtcctatta caggacctgg tagtcgtccg
    14221 cttaaatcct tgagccacat gcttaaagga aaacaagggc gttttcgtca aaacctgctt
    14281 gggaagcgtg ttgacttctc aggtcgttca gttattgctg tgggtccaac gctaaaaatg
    14341 taccaatgtg gtgtaccacg tgagatggct attgagcttt tcaagccatt tgtgatacgt
    14401 gagattgttg cccgcgaatt tgccggcaac gtcaaagcag ctaagcgtat ggttgagcgt
    14461 ggcgatgagc gtatctggga tattctagaa gaggttatca aggagcatcc agtcctgctt
    14521 aaccgcgcac ctacccttca cagattaggg attcaggcct ttgagccggt gcttattgat
    14581 ggtaaggctc ttcgtcttca cccgcttgtg tgtgaggcct acaatgccga ctttgacgga
    14641 gaccaaatgg ctattcacgt gccgctttca gaggaagcac aggcagaggc tcgtttgttg
    14701 atgcttgctg ctgagcatat tcttaaccct aaggacggta agccagttgt aacaccttct
    14761 caggatatgg tgctaggaaa ctactaccta acaatggaag atgctggtcg tgaaggcgaa
    14821 ggtatggtct ttaaggacaa ggacgaagcg gtaatggctt accgtaatgg ctatgttcac
    14881 cttcatagtc gtgttggtat tgctgttgac agtatgccaa gcaagctttg gaaggatagt
    14941 caaagacaca aaatcatggt gacaacggtc ggtaagatct tgtttaatga catcatgcca
    15001 gaggaccttc cttacctcca agagccaaat aatgctaact tgacagaggg cactccagat
    15061 aaatatttct tgaagccagg tcagaatatt caggaggtta ttgatagctt accgatcaat
    15121 gtgcccttca agaagaaaaa tcttggtaac atcattgcgg aaaccttcaa gcgtttccgt
    15181 acaacagaaa catcggcctt tcttgaccgc ttgaaggacc ttggctacta tcattcaacc
    15241 cttgcgggct tgacggttgg gatcgctgat attccggtta ttgacaacaa ggctgagatc
    15301 atcgaggctg ctcaccatcg tgttgaggaa attaataagg ccttccgtcg aggcttgatg
    15361 actgatgatg atcgctatgt tgcagtcaca acaacatggc gcgaggcaaa agaagccctt
    15421 gagaagcgtc tgattgaaac acaggatcct aagaacccaa tcgttatgat gatggactca
    15481 ggagcgcgtg gtaacatctc taacttctcg cagcttgccg gtatgcgtgg cttgatggct
    15541 gctcctaatg gccgtattat ggagcttcct atcctgtcta acttccgcga aggcttgtct
    15601 gttttggaaa tgttcttctc aactcatggt gctcgtaagg gtatgactga tacggctctt
    15661 aagacagctg actcaggcta tctgacacgt cgtttagttg atgttgcgca agatgtcatc
    15721 attcgtgagg acgattgtgg tacagaccga ggccttctta ttcgagctat cacagatggc
    15781 aaggaagtca ctgaaacact tgaggagcgc ttgcagggtc gatacactcg taaatcagtc
    15841 aagcaccctg aaactggtga ggtattgatt ggtgctgacc aattaatcac tgaggacatg
    15901 gctcgcaaga ttgttgatgc tggtgttgaa gaggttacca ttcgctcagt atttacctgt
    15961 gctactcgtc atggagtgtg tcgtcactgt tacggtatca acctagcgac aggtgatgcg
    16021 gttgaggttg gtgaggctgt tggtactatc gctgcccaat ctattggtga gcctggtact
    16081 cagctgacca tgcgtacctt ccacacagga ggggttgcct ctaataccga tatcacacag
    16141 ggtcttcctc gtatccaaga aatctttgaa gcgcgcaacc ctaaagggga agcagttatc
    16201 acagaggtta aggggactgt tattgagatt gaagaggacg catcaactcg tactaagaag
    16261 gtctacgttc aaggtaaaac aggcatgggt gaatatgttg tgccatttac agcgcgtatg
    16321 aaggttgagg ttggtgatga ggtcaatcgt ggagctgccc ttacagaagg gtcaatccag
    16381 cctaagcacc tccttgaggt tcgtgatacc ttgtcagttg agacctactt gcttgctgag
    16441 gttcaaaagg tttaccgcag ccaaggggta gaaatcggag acaagcacgt tgaggttatg
    16501 gttcgtcaaa tgcttcgcaa ggtacgtgtc atggatccag gtgatacaga tcttctgcca
    16561 ggaaccttaa tggatattgc agactttaca gatgccaata aggagattgt tatctctgga
    16621 ggtattcctg cgacctctcg tccagtgctt atgggaatca caaaagcctc acttgagact
    16681 aactcattcc tatcagcagc ttccttccag gaaaccactc gcgtgctgac agacgctgct
    16741 atccgaggca aaaaagacca tctattgggg cttaaggaaa atgttatcat tggtaagatc
    16801 attccagcag gtactggtat ggttcgttac cgtaacattg aaccgcaagc tatcaatgag
    16861 gttgaggtta tcgaagaagc tgaagctaca gaagagccag caattattaa ggaataagaa
    16921 ataaaaggag ctagccttag ctccttttat catgctaaaa tcattagatt aattgggctc
    16981 catgtcaact atagtaggtg actgataact aagcacgaga ggagacgaag gtcgtcttct
    17041 cttttgtcat gttcaaagca agcatagata agtttcttga aattgtcaac gtttctgaat
    17101 ccaaatgcat tgcgcttgat gtctttgatc agtttgctag tcgcttcaaa cttggcgtta
    17161 gaataaggta gttcaatggc attagtgata tagtctttat at
//
LOCUS       DARYXW010000044        17075 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.044, whole genome shotgun sequence.
ACCESSION   DARYXW010000044 DARYXW010000000
VERSION     DARYXW010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17075)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17075)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17075
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.044"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(15..986)
                     /locus_tag="TV191_001164"
     CDS             complement(15..986)
                     /locus_tag="TV191_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEL1507682.1"
                     /translation="MTYQKKLIAASMALASVFMLQTVHAAANNVQQVIDETYVQPDYV
                     LGYSLSAEQREQTLALLHYNSASDNKLSTLNTTAYASIMNVADDPSLQLYSSVRIQKL
                     GAKETLKVTIVTPENITKVTQDMYRNAAVTLGIEHANITVAAPIPVTGESALAGIYYS
                     LEKNGAKVPEENKKLAQEELSTLSNINTENAGKTGYDADKLNVALTDIKAAVAKAGEG
                     VNEEKVRQIVTETLDHYGLTKAVTPDQINLIINFALNLSNSGVISNENFTKTLNALKD
                     SIVEKAGSTFKNINVNFDATEALKTGQGILQQIIDFFRGLIDSLMGN"
     gene            complement(1299..1739)
                     /locus_tag="TV191_001165"
     CDS             complement(1299..1739)
                     /locus_tag="TV191_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL1507683.1"
                     /translation="MTKKAYLSLFTILLLFPLSACDFKAQDSTGKKLKSSHQLEKRCK
                     ALKKETDKSPNEVSKEEGIAAEQIIVSISDDGFVTSHGDHYHFYNGEVPYDSLFSSEL
                     LPPKDYQFDQKDVINEVKNGYVIKTDDHYYFYLKDNNHQENLRS"
     gene            complement(1736..2671)
                     /locus_tag="TV191_001166"
     CDS             complement(1736..2671)
                     /locus_tag="TV191_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HEL1507684.1"
                     /translation="MIRGFKKTIVAVGLLAVLLGLSACHQSSSSRKAGLVIKTSFYPI
                     YAMTKEICGDLNDVQVIAQNTSIHSYEPSPTVVAKVYDGDVFIYHSKILEAWAADLAP
                     QLEKKGLAVMEGTSHLTLDKVQGLEHFTIKKGMNTDALYDPHTWTDPILASQEAEQIA
                     ALLSQKDPAHKAVYLQNAKRFKAKAQKLVKTYKEKFESLGRKTFVTQHTAFSYLAKRF
                     DLKQLGIAGISPEQEPSPRQLAQIDRFIKKYDVKTIFVEENASDKLAKTLAQSNGVAI
                     DILSPLEVVPADQKTYLEHLKMNLETLYRVLESET"
     gene            complement(3109..3522)
                     /locus_tag="TV191_001167"
     CDS             complement(3109..3522)
                     /locus_tag="TV191_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEL1507685.1"
                     /translation="MELKAIHHIAIIVSDYEVSKDFYVNKLGFEIIRENHRPDRHDYK
                     LDLKCGAIELEIFGNKKTDPAYQAPPKRIGRPEYDKEACGLRHLAFHVKPIEAYIEQL
                     MAKGIAVEPLRYDDYTGKKMTFFFDPDGLPLELHE"
     gene            complement(3620..4375)
                     /locus_tag="TV191_001168"
     CDS             complement(3620..4375)
                     /locus_tag="TV191_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HEL1507686.1"
                     /translation="MAKRTHRRRQKRRKMSFARGILVVLLLIIGLALLFNKPIRNTLI
                     AWNSNKYQVTKVSKKTIKKNKEAKSSFDFQAVQPVSTESVLQAQMDAQQLPVIGGIAI
                     PELGINLPIFKGLGNTELIYGAGTMKEDQVMGGENNYSLASHHIFGLTGSSEMLFSPL
                     ERAKEGMSIYLTDKERIYEYEINAVFTVTPERIDVINDTPGLKEVTLVTCTDYEATER
                     IIVKGAIKNEYEFNKAPDDVLKAFNHSYNQMST"
     gene            complement(4380..6875)
                     /gene="gyrA"
                     /locus_tag="TV191_001169"
     CDS             complement(4380..6875)
                     /gene="gyrA"
                     /locus_tag="TV191_001169"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEL1507687.1"
                     /translation="MQDKHLVDVNLTSEMKTSFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRHMLVD
                     GHGNFGSMDGDGAAAQRYTEARMSKIALELLKDINKNTVDFQDNYDGNEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLAEAIDAVKMVMENPDCTTRDLMEVLPGPDFPTG
                     ALVMGRSGIHKAYETGKGSIVLRSRTEIETTSTGRERIVVTEFPYGINKTKVHEHIVR
                     LAQEKRIEGITAVRDESSRQGVRFVIEVRRDASANVILNNLFKLTSLQTNFSFNMLAI
                     EGGIPKILSLRQIIDNYILHQKDVITRRTQFDKDKAEARAHILEGLLIALDHLDEVIA
                     IIRNSETDIIAQAELMSRFDLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILARPERIEAIIKEEMEEIKRKYANPRRTELMIGEVLSLEDEDLIEEEDVLITLS
                     NNGYIKRLAQDEFRSQKRGGRGVQGTGVNDDDFVRELVSTSTHDTLLFFTNFGRVYRL
                     KAYEIPEYGRAAKGLPVINLLKLDDGETIQTIINAKKEDILDKYFFFTTKQGIVKRTE
                     VSEFSNIRQNGLRALNLKEGDELINVLLTNGQEDIIIGTRSGYSVRFNEATIRGMGRS
                     ATGVRGVKLREEDWVVGASRINDKQEVLVITENGYGKRTSAAEYPTKGRGGKGIKTAN
                     ITAKNGQLAGLMTVDGSEDIMVITTKGVIIRTNVSSISQTGRSTLGVKVMRLDTDSKI
                     VTFTLVQAEDNDPTAIAQTDTALTEAPINSSKE"
     gene            7067..8050
                     /locus_tag="TV191_001170"
     CDS             7067..8050
                     /locus_tag="TV191_001170"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEL1507688.1"
                     /translation="MTATKQHKKVILVGDGAVGSSYAFALVTQNIAQELGIIDIFKEK
                     TQGDAEDLSHALAFTSPKKIYAADYADCHDADLVVLTAGAPQKPGETRLDLVEKNLRI
                     NKEVVTQIVASGFKGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFRQAL
                     AAKIGVDARSVHAYIMGEHGDSEFAVWSHANVAGVGLYDWLQANRDVDEQGLVDLFIS
                     VRDAAYSIINKKGATFYGIAVALARITKAILDDENAVLPLSVFQEGQYEGVEDCYIGQ
                     PAIVGAYGIVRPVNIPLNDAELQKMQASANQLKTIIDEAFSKEEFASAAKN"
     gene            complement(8255..9622)
                     /locus_tag="TV191_001171"
     CDS             complement(8255..9622)
                     /locus_tag="TV191_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEL1507689.1"
                     /translation="MSKIVVIGANHAGTACIKTMLTNYGDANEIVVFDQNSNISFLGC
                     GMALWIGEQISGPEGLFYSNKEELESLGAKVYMESPVQSIDYDAKTVTALVDGKEHVE
                     SYDKLIFATGSQPILPPIKGAEIKEGSLEFEATLENLQFVKLYQNSADVISKLENKDI
                     KRVAVVGAGYIGVELAEAFQRKGKEVILIDVADTCLAGYYDRDLTDVMSKNLEEHGIQ
                     LAFGETVKEVAGDGKVEKLITDKNEYDVDMVILAVGFRPNTALGAGKIELFRNGAFLV
                     NKHQETSIPGIYAIGDCATIYDNATRDTNYIALASNAVRTGIVAAHNACGTALEGIGV
                     QGSNGISIYGLHMVSTGLTLEKAKCLGFDAAVTEYTDNQKPEFIEHGNFQVTIKIVYD
                     KESRRILGAQMASHEDISMGIHMFSLAIQEGVTIEKLALTDIFFLPHFNKPYNYITMA
                     ALGAE"
     gene            complement(9872..10474)
                     /locus_tag="TV191_001172"
     CDS             complement(9872..10474)
                     /locus_tag="TV191_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HEL1507690.1"
                     /translation="MFRVLKRILGLAVLIFCLYEAVTIHKNVHRVLQYKPTVERILAE
                     NGNKADVDLVLAMIYTETKGGEADVMQSSESSSGIRDSITDSQSSIEYGVRLLSHNLA
                     LAEKAGVDPWTAVQAYNFGTAYIDYVAKNGGQHTIELATNYSRTVVAPSLGNTTGKTY
                     FYYHPLALLSGGKLYCNGGNIYYAQEVHVNLYLIELMSLF"
     gene            complement(10475..11452)
                     /locus_tag="TV191_001173"
     CDS             complement(10475..11452)
                     /locus_tag="TV191_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEL1507691.1"
                     /translation="MLDIYIKGIVIHQFTPNDTELILSDALVAITPRIDEYFRKKLAK
                     VFSDDAKRGQLEADHAFFTTIGTELLETSVTIAKLWKEEFVASEHQKTNDLVFIQFDK
                     EGVPYLAFLRIALKEHFAHLSDDHENPITITQNNLPSPTQAPDEALVINRQTGYYYLI
                     EKRMKHNGSFAHYFSEKLLKVTPEQSVKKSIQMLEQTAQKVAENFNQDDFAFQSKMKV
                     ALAKNLEEETALSPEKLADQLFDQNLTARLTFVDQVKEMIPEPIQVSDIDHSRQLKKL
                     ETQKLSLSNGIELLVPNAVYQDAESVEFILNDNGTYSILIKNIEDIKNN"
     gene            complement(11455..12714)
                     /locus_tag="TV191_001174"
     CDS             complement(11455..12714)
                     /locus_tag="TV191_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEL1507692.1"
                     /translation="MMFNNENYKDYDQELWEAIQAEEDRQEHNIELIASENMVSKAVM
                     QAQGSVLTNKYAEGYPSKRYYGGTEYVDIVESLAIERAKKLFGAAYANVQPHSGSQAN
                     AAAYMALINAGDTVLGMDLAAGGHLTHGSPVNFSGKTYQFVGYTVDKETEKLDYAAIL
                     KQAKAVQPKLIVAGASAYSRQIDFEQFRFIADQVGSYLMVDMAHIAGLVAAGLHQNPV
                     PYAHIVTSTTHKTLRGPRGGLLLTNDEAISRKMNAAIFPGLQGGPLEHVIAAKAVAFK
                     EALDPAFTDYARAVIANTAAMAEVFAKDDRFRLISGGTDNHLFLVDVTKVIENGKLAQ
                     ALLDEVNITLNKNAIPFETLSPFKTSGIRIGCAAITSRGMGVDESRTIAHLIIKALVN
                     HQQPEILEEVRYEVRRLTDAFPLYKKN"
     gene            complement(12726..13157)
                     /locus_tag="TV191_001175"
     CDS             complement(12726..13157)
                     /locus_tag="TV191_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1507693.1"
                     /translation="MLRPLDQTDCQAICDINDQSLGYKVSLELTKSQLEKLRSDKHHY
                     LLGYADTKTNLLLGYLHAECYESLYSEKGFNILALAVRLDHQGRGIGRRLLAALEEKA
                     KQEKVSFIRLNSASHRTEAHAFYRKLSYVDDKTQLRFMKLL"
     gene            complement(13171..13764)
                     /locus_tag="TV191_001176"
     CDS             complement(13171..13764)
                     /locus_tag="TV191_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEL1507694.1"
                     /translation="MITHLIETIKAGGALILPTETVYGLFAQALNEEAVNAVYRLKKR
                     PRDKAMNLNVADFESILAFSKQQPAYLNKLYEAFLPGPLTIILKANAQTPYWINSGLK
                     TVGFRLPSHPLTAKIIRATGPLIGPSANLSGSKSGKCFNDIVKAFDGKVDGYADDAYL
                     TGKDSTILDLSSPKVSILRQGAITKEQLLAKVPELPF"
     gene            complement(13736..14584)
                     /gene="prmC"
                     /locus_tag="TV191_001177"
     CDS             complement(13736..14584)
                     /gene="prmC"
                     /locus_tag="TV191_001177"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEL1507695.1"
                     /translation="MNYAKQLRAYEDRLENIGEDRENLAYVFKELKQWTSLDFLLHQN
                     QEVTSEDQALLERIFLALSQHVSPQYITGRAYFRDLVLAVDSRVLIPRPETEELVELI
                     LKENDATRKSVLDIGTGSGAIAIALKKARPNWQVTASDISADALSLAYSNALDHHVEI
                     AFEQSDLFSKLSGQFDIIVSNPPYIAYEDKDEVGLNVYQSEPHLALFAAENGFSIYRR
                     IIEQASAYLTTSGKLYFEIGYKQGEGLKRLLSKRFPQKRIRVLKDMLGKERMVVVDDN
                     TFDRDN"
     gene            complement(14581..15663)
                     /gene="prfA"
                     /locus_tag="TV191_001178"
     CDS             complement(14581..15663)
                     /gene="prfA"
                     /locus_tag="TV191_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEL1507696.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPEVVSDTKRFMALSKEEASTR
                     ETVAAYRQYKAIIQSIDDAEEMIKEAGGDPDIEEMAKEELKEAKSAKEAYEDKLKLLL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLAMYQKFAESQGWRFEVMEASYNGVGG
                     IKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRIDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNRDKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEIVDALVLYDQTQKLESLNNQ"
     gene            complement(15705..16274)
                     /locus_tag="TV191_001179"
     CDS             complement(15705..16274)
                     /locus_tag="TV191_001179"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEL1507697.1"
                     /translation="MAQLYYKYGTMNSGKTIEILKVAHNYEEQGKPVVIMTSALDTRD
                     GFGIVSSRIGMRREAVPISNDMDIFAFIAELQEKPYCVLIDECQFLSKQNVYDLARVV
                     DELNVPVMAFGLKNDFQNELFEGSKYLLLLADKIDEIKTICQYCSKKATMVLRTEHGK
                     PVYEGAQIQIGGNETYIPVCRKHYFHPPI"
     gene            16461..16646
                     /locus_tag="TV191_001180"
     CDS             16461..16646
                     /locus_tag="TV191_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEL1507698.1"
                     /translation="MPFVTIDLFEGRSQEQKIALAREVTEVVSRIAQAPKEAIHVVIN
                     DMPEGTYFPHGEMKTKA"
     gene            16701..>17075
                     /locus_tag="TV191_001181"
     CDS             16701..>17075
                     /locus_tag="TV191_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEL1507699.1"
                     /translation="MIATDQIKMMGTIIDICIDSSKAKQQAATIRELLTLYNHRFSAS
                     DDSSELMAINHMAGIQPVRVHSDLFDLISIGKEHSLAYPSNLNITLGPLVQSWRIGFS
                     DAKLPDEATIDRRLRLTNPNHII"
BASE COUNT         4800 a         3750 c         3261 g         5264 t
ORIGIN      
        1 cttttatcta tttatcagtt acccattagg ctgtcaatca atcctctaaa gaaatcaata
       61 atttgctgaa ggattccctg tccagtcttt aaggcttcag tagcatcaaa gttcacgttg
      121 atatttttaa aggtagatcc ggccttttca acaatactat cctttaaagc attcagcgtt
      181 ttggtgaagt tttcattgga aatcacgcca ctatttgaga ggttaagcgc gaaattgata
      241 ataaggttaa tctgatcagg tgttactgcc ttggttaacc cataatgatc taaggtttct
      301 gttacaattt ggcgcacctt ttcctcatta accccttctc cagcctttgc gacagcagct
      361 ttaatatcag taagcgcaac atttagctta tctgcatcat agcctgtttt acctgcattt
      421 tcggtattga tattagatag ggttgatagc tcctcttgtg ccagcttctt gttttcctct
      481 gggactttgg caccattttt ttcgagtgaa taataaatac cggctaaagc tgattctcca
      541 gtaactggga ttggtgcagc tacagtaata ttggcatgct caatgcccaa ggtcacagcg
      601 gcgttacgat acatatcttg cgtcacctta gtgatatttt caggtgttac aatagttacc
      661 ttaagcgttt ctttagctcc cagcttttga atcctaactg aggaataaag ctgtaggctc
      721 ggatcatctg ctacattcat gatactagca taggcagttg tatttagggt gcttaatttg
      781 ttatcagaag cactattgta gtgaagcaag gccaaggttt gctctctttg ctcagcagac
      841 agtgaatagc ctaaaacgta atcaggctga acataggttt catcaattac ctgttgaaca
      901 ttattagctg cagcgtgtac tgtttgaagc ataaataccg aagccaaagc catactggct
      961 gctattaatt tcttttgata agtcattttt ctacctcttt tgtgttataa attttccttt
     1021 acgagaatcc tccagaaaag acgattaaag ccaaagtatc taggtgccta gtaagaccgt
     1081 tttacttagc tctgcaaagg gcaatattcc tagtcttttt caaaatctaa cgcctctatt
     1141 gtagcatttt tacctcaata agacgattaa aaagctgaaa caaagcatag ctagaatggc
     1201 caagcactat ttttacaaca aaaaaactag tgcataatgg cagcttagat gtagctacta
     1261 tcactagtcc aatgattatc ttatgcagca accagtcttt atgatctgag gttttcttga
     1321 tggttattgt cctttaaata gaaataataa tgatcatcag ttttgatgac atagccattt
     1381 ttaacctcat taatcacgtc cttttgatca aactggtagt ccttaggcgg taataactct
     1441 gaggaaaaaa ggctatcata aggcacctca ccattgtaaa aatggtaatg gtcaccatga
     1501 gaggtaacaa aaccatcatc cgagatagac acaataattt gctctgctgc tatcccctct
     1561 tccttgctaa cttcattagg acttttgtca gtctctttct ttaaggcttt gcaccttttt
     1621 tccaattgat gagatgattt tagcttcttg cctgtgctat cttgggcttt aaagtcacaa
     1681 gcggacaaag gaaataatag taagatagtg aataacgata aataagcttt tttggtcatg
     1741 tttcactctc caatacacga tatagtgttt ctaaattcat ttttaaatgc tctagataag
     1801 ttttttgatc agctggaacc acctcaagcg ggcttaggat atcaattgct acaccgttac
     1861 tttgagccaa ggttttggct agcttatctg aagcattttc ttcgacgaaa atcgtcttca
     1921 catcatattt tttgataaag cggtcaattt gagctaattg gcgaggacta ggctcttgct
     1981 caggagatat ccctgcaatt cccaattgct ttagatcaaa tctcttagct aggtaggaaa
     2041 aggctgtatg ctgtgtcaca aaggttttcc tacctagaga ttcaaacttt tccttatagg
     2101 tcttcactaa tttttgagcc ttagccttaa aacgcttagc attttgcaaa taaactgcct
     2161 tgtgagcagg atctttttga ctcaataaag ctgcaatctg ctctgcctct tgactagcta
     2221 agataggatc agtccaagtg tgaggatcat acaaggcatc ggtattcatt ccttttttta
     2281 tggtgaagtg ctccaagcct tgaaccttgt ctaatgttag atgtgatgtc ccctccatga
     2341 ctgctaatcc ctttttttcc agctgtggtg ccaaatccgc agcccaagct tctaatatct
     2401 tggaatggta aataaagaca tctccatcgt aaaccttagc aacaactgtc ggacttggct
     2461 catacgagtg tatgctagtg ttttgggcaa tgacctgaac atcatttaaa tccccgcaaa
     2521 tctcctttgt catagcataa ataggataaa agcttgtttt tatgaccaaa ccggccttcc
     2581 tactgctaga gctctgatga caggctgata gacccaaaag tactgctaat agtcctactg
     2641 cgacaattgt tttcttgaat cctctaatca tatctactct cttaactagt taatgaccta
     2701 aaaaggatac catgatttaa ctgaaatgtc aatattttat cattttagcg cacgacgtac
     2761 acgcatgaag aaaatgcatg taagcctttt ttagccccat gcatttttta atctatttct
     2821 agcgttttga cattgcaata tcatcagttt gtcaatttca atgtgatgac ttcatcacat
     2881 tttgctaaaa aggccatagt gatgataaaa aaccgctacc agaaagcgta aatgtcttct
     2941 tgcttttgtc gtgattttag tgaaccgcct accaactgaa ctgatgctgg cttaaccatt
     3001 tcctggccac catcaaaagc ctgcctctca attaacaagc ttactcaagg aagaggtgac
     3061 tgagccatgc atccgtctta gttatgacta acagcttatc ttggcatttc attcatgtaa
     3121 ttccagtggc aggccatcag gatcaaaaaa gaaggtcatc ttcttaccag tataatcatc
     3181 atacctaaga ggctcgacag caatgccctt agccattaat tgttcaatat aagcttcaat
     3241 aggcttaaca tgaaaagcta aatgacgaag cccacaggcc tctttgtcat attcgggcct
     3301 accgatacgc ttaggcggtg cctgataagc tggatcagtc tttttattgc caaaaatctc
     3361 taattcaatg gctccacatt ttaaatccaa tttgtaatca tgtctatcag gccggtgatt
     3421 ttcacgaata atctcaaagc caagcttatt gacataaaaa tccttagaga cctcataatc
     3481 cgaaacaatg atagcaatat gatgaatagc cttaagctcc atatgattta gttcctttat
     3541 taaataaaaa aagtgaaaca aagcaatgcc aagattactt tgtttcaccc ctcgtagcga
     3601 cccctcgcct agattaggct taggttgaca tctgattgta agagtgatta aaggccttca
     3661 aaacatcgtc aggtgctttg ttaaactcat actcgttttt gattgctcct ttgacaatga
     3721 ttcgctctgt tgcctcataa tccgtacagg tgaccaaggt tacctccttt agccctggtg
     3781 tgtcattgat aacatctatt ctctcaggtg tgaccgtaaa gacggcattg atctcgtact
     3841 cgtaaatacg ctccttatct gtaaggtaaa tagacatccc ttcttttgct ctttcaagcg
     3901 gtgagaataa catttcagaa gagcctgtta gtccaaaaat atgatgactg gctaaggagt
     3961 aattgttttc tcctcccata acctggtcct ctttcatggt accagcaccg tatataagct
     4021 ctgtgttgcc aagcccttta aagattggta ggttaatacc aagctctggt atggcaatac
     4081 ctcctattac tggaagctgc tgggcgtcca tttgagcctg taagacactt tcggtgctaa
     4141 ctggctgaac tgcttgaaaa tcaaagcttg actttgcttc cttattcttt ttaatcgtct
     4201 tttttgaaac ctttgtaact tgatatttat tagaattcca agcaatcagg gtgtttctaa
     4261 tgggcttgtt aaataacaag gctaagccta tgattaacaa taagacgact agaatacctc
     4321 tagcaaagga catctttctt cgtttttgtc ttctcctgtg ggttcttttt gccattcatt
     4381 tactccttgc tagaatttat tggtgcttct gttaaagctg tatcagtctg agcgattgct
     4441 gttggatcgt tgtcttcagc ctgtaccaag gtaaaggtaa caatcttaga atctgtatct
     4501 agcctcataa ccttaacacc aagtgttgaa cggccagtct gagaaatact tgaaacattg
     4561 gtacgaataa tcacaccctt cgttgtgatc accataatat cctcactgcc atcaacagtc
     4621 atcaggccag ccaactggcc attttttgcg gtgatattag ctgttttgat tccttttcca
     4681 cctcgaccct tagttgggta ttcggctgca ctggtacgct taccatagcc attttcggtg
     4741 atgactaaga cctcttgctt gtcattgata cgagaagctc cgacaaccca atcttcctca
     4801 cgaagcttga caccacgaac acccgtagcg ctacgcccca tgcctcgaat ggtagcttca
     4861 ttaaagcgaa cagaataacc tgatcttgtt ccaatgataa tatcttcctg accatttgtc
     4921 aagagaacat taatcagctc atctccttcc ttgagattaa gggctcgtag accattctga
     4981 cgaatattgc taaactctga tacctcagtt cgtttgacaa tcccttgctt tgttgtaaag
     5041 aagaaatatt tatcaagaat gtcttctttt ttagcattga taattgtttg aatggtttca
     5101 ccatcatcta gctttagtag attgataaca ggaagtcctt ttgcagcacg tccatattct
     5161 ggaatctcat aggcctttaa gcgatagacg cgcccaaaat tggtaaagaa aagcaatgtg
     5221 tcatgtgtac ttgttgagac aagctcacga acaaagtcat cgtcattgac acctgttccc
     5281 tgtacaccac gaccaccacg cttttgagat cgaaactcgt cttgagcaag gcgcttaatg
     5341 tagccattgt ttgatagggt gatcaaaaca tcttcttcct cgatcaaatc ctcatcttct
     5401 aatgacaata cctcaccaat catcaattct gtgcggcgag gattagcgta cttgcgcttg
     5461 atctcctcca tttcttcctt gatgatggct tcgatacgct ctggccttgc caaaatatct
     5521 gccaaatctg caatcaaagc cagtaggtca tcgtattctg attgaatttt atcacgttcc
     5581 aagccggtca aacggcgaag acgcatgtct aaaatagcct gactttggcg ttcagacaag
     5641 tcaaaacgag acatcaattc tgcttgtgcg ataatatctg tctcgctatt gcggataatg
     5701 gcaataacct catctagatg gtcaagagcg ataagtaagc cctctaaaat gtgtgcccta
     5761 gcttctgcct tgtccttgtc aaattgagtc ctgcgtgtaa tgacgtcctt ttgatgtaga
     5821 atataattat caataatctg tctcagtgac aagattttag gaatcccgcc ttcaatggct
     5881 agcatattga agctaaagtt tgtctggaga cttgtcaatt tgaataggtt atttaaaatc
     5941 acattagcag atgcatcgcg acggacttca atgacaaatc gtaccccttg tcggcttgat
     6001 tcgtcacgaa cagctgtaat gccctcaata cgcttttctt gggctaagcg aacaatatgc
     6061 tcatggacct ttgttttatt aatgccataa gggaattctg tgacgacaat ccgctcccgt
     6121 cctgtactag tggtttcaat ctcggtgcgt gaacgcaaaa cgattgatcc cttaccagtc
     6181 tcataagcct tatgaattcc tgaacgtccc atcaccaagg cacctgtagg aaaatccggc
     6241 cctggaagaa cctccattaa atctctggta gtgcagtcag gattttccat gaccatctta
     6301 acagcgtcta tggcctcagc taaattatga ggtggaatat tggtagccat accaactgcg
     6361 attccggtgg caccattgac caataaattg gggaagcgag ccggtaagac taagggttct
     6421 ctttcattac catcgtagtt atcctgaaag tcaacagtat ttttattaat atcctttaag
     6481 agctctagcg cgattttgct catacgagcc tcagtataac gctgagccgc agcaccgtca
     6541 ccgtccatag aaccaaagtt tccatgacca tcgacaagca tgtgacgata gctccaccac
     6601 tgggccatac ggaccatcgc ttcatagatg gacgaatccc catgtgggtg gtacttaccc
     6661 atgacatcac cggtaatacg agcagatttt ttatgtggct tatcaggtgt gacgcctagc
     6721 tcattcatgc cataaaggat acgacgatga acaggcttta agccatctcg tacatctgga
     6781 agtgctcttg ctacaataac gctcatagca taatcaatga aactcgtttt catctcactt
     6841 gtcagattga cgtcaactaa atgtttatct tgcatttaag gaatgctcct tttctagtca
     6901 atactctttt aattatacca taaaatcctt attttttctg attggaaacg ctgtccgaaa
     6961 acaattttca taatttggtc gaatatcatg acaaagacat taaaatgtgt taaaataaga
     7021 tcgtatgagc aatttgctct aactaaaatg aaggagatgt ttagaaatga ctgcaactaa
     7081 acaacataaa aaagtcatct tggttggcga tggtgctgta ggctcttctt atgcctttgc
     7141 actagtaacc caaaatattg cccaagagct tggtattatt gatattttta aagaaaaaac
     7201 tcaaggagat gctgaggatt taagccatgc gcttgccttt acctccccta aaaagatcta
     7261 tgctgctgat tatgctgact gtcacgatgc tgacctagtt gttttaacag ctggcgctcc
     7321 tcaaaagcca ggtgagactc gtcttgacct tgttgagaaa aatctacgta ttaataaaga
     7381 agtggttact caaattgtgg cctcaggctt taagggaatt ttccttgttg ctgctaatcc
     7441 ggtggatatt ttgacctatt caacctggaa attctcaggt ttccctaagg aacgcgttat
     7501 cggttctgga acatcacttg actcagcacg cttccgtcag gcacttgctg ccaaaattgg
     7561 tgtagacgca cgttctgttc atgcctacat catgggtgag catggagatt cagaatttgc
     7621 tgtttggtca catgctaatg ttgcaggggt tggattgtac gactggcttc aagctaatcg
     7681 tgacgttgat gaacaaggct tggtagacct ctttatctct gtacgtgacg cagcttactc
     7741 tatcatcaat aaaaagggtg ctaccttcta tggtattgca gtcgccctag cacgtattac
     7801 aaaagctatc cttgatgatg aaaatgcagt tcttccactt tctgttttcc aagaaggcca
     7861 atacgaaggc gttgaggatt gctatatcgg tcagcctgct attgttggtg cctatggtat
     7921 tgttcgtcca gtcaatatcc cattgaatga cgctgagctt caaaaaatgc aagcttcagc
     7981 aaaccaattg aagactatta tcgacgaagc cttctctaaa gaagagtttg cgtctgctgc
     8041 taaaaactaa ttaaaaaatg aatgtgttag atcttgctct aacgttttgg aatcactaca
     8101 aaaagcctaa tccaatcgga taggcttttt tcatgcgtct aacagcgagg tgcaagacaa
     8161 agcacgcttt cattaagcat cgtgtgtgct atgcttatag tcttaagtca caaaaaagac
     8221 aaccagcttt atgagctggc tgcttattag cttgttattc agcaccaagt gctgccattg
     8281 taatgtagtt atatggcttg ttaaagtgcg gtaagaagaa aatatcagtc aaagctaatt
     8341 tctcaatggt cactccttct tggatagcaa gtgagaacat atgaattccc attgaaatat
     8401 cttcatgtga ggccatttga gcacctagaa tacgacgtga ttctttatcg tagacaatct
     8461 taatggttac ttggaagtta ccatgctcga taaattctgg tttttgattg tcagtgtatt
     8521 ctgttactgc tgcatcaaag ccaaggcatt ttgctttctc aagagttaag ccagttgata
     8581 ccatgtgcaa gccgtagata gagataccat ttgatccctg cacaccaata ccctcaagag
     8641 ctgtgccaca agcgttatga gctgcgacaa tccctgtacg aacagcattt gaagcaaggg
     8701 caatataatt ggtatcgcga gttgcgttgt catagatggt tgcacaatca ccgattgcat
     8761 aaatccctgg aatagatgtt tcttggtgtt tgttaacaag gaaggcacca ttacggaaaa
     8821 gctcaatctt gccagcacca agagctgtat ttggacggaa gccaactgca aggataacca
     8881 tatcaacatc atattcattc ttatcagtga ttagcttttc aaccttgcca tcaccagcaa
     8941 cctctttgac agtttcccca aaggccaact gaataccatg ctcttctagg tttttagaca
     9001 tgacatctgt caaatcacga tcatagtagc ctgctagaca agtatccgca acatcaatca
     9061 gaataacctc tttgccctta cgttggaagg cttctgcaag ctctacacca atgtagcctg
     9121 caccaacgac tgcaacgcgc ttaatgtctt tgttttctaa tttcgaaatg acatctgctg
     9181 aattttggta caatttaacg aattgaagat tttcaagtgt tgcttcaaac tctaatgagc
     9241 cctctttgat ttctgcacct ttaattggtg gcaagatagg ctgtgaacca gttgcaaaaa
     9301 ttaatttgtc atatgactca acatgctctt tgccatcaac aagggctgtc actgttttag
     9361 catcgtagtc aatagattga actggtgatt ccatgtaaac cttagcacca agggactcta
     9421 gctcttcctt atttgagtag aataagccct ctgggccaga aatttgttcg ccaatccaaa
     9481 gtgccatacc acagcctaag aatgaaatat ttgagttttg gtcaaataca acaatctcat
     9541 tagcatcacc atagtttgtt aacatagtct tgatacatgc cgtacctgcg tggtttgcac
     9601 cgataacaac gattttactc atatgattat gttcctcatt tcacaattta tattaggtct
     9661 ctattataac acagggaaaa agcgcttcca actaaaatgc tcatttttct tgctttttta
     9721 taccgttttt tagtcaataa ataagacagc ctatcatttg ttgaagggtc gtacaaagac
     9781 cggtttgctt cagttaagtc aagacgacat tcttattcaa ctattttccc aaattcatta
     9841 catgattaag accatttttt gtcgttaact tctaaaaaag actcataagc tcaatcaggt
     9901 aaagattgac atgtacctct tgagcataat aaatattgcc gccgttgcaa taaagctttc
     9961 caccagagag gagggctaag gggtggtaat aaaaataggt ttttccagta gtatttccta
    10021 ggctgggtgc aacgacagtt ctagaatagt tagtggctag ttcaattgta tgctgaccgc
    10081 catttttagc aacgtaatca atataggcgg ttccaaaatt gtaagcttga acagctgtcc
    10141 aagggtctac gccggctttt tctgctaaag ctaaattgtg agatagcaat ctgacaccat
    10201 actcaatgct agattgacta tcggtgatcg aatcccttat gccagagctg ctttcgcttg
    10261 actgcataac gtcagcttct cctcccttag tttccgtgta tatcatggct agtaccagat
    10321 cgacgtctgc tttgttaccg ttttctgcta aaatacgctc tactgttggc ttgtattgta
    10381 ggactctgtg cacattctta tgaatggtaa ctgcttcgta caggcaaaaa atgaggacgg
    10441 ctaatcctaa gatacgcttt aacactctaa acatttagtt atttttgata tcctctatat
    10501 tttttatcaa tatggaatag gttccgttgt cattcaagat aaactctact gactcagcat
    10561 cttgataaac tgcattaggg acaagaagct caattccatt tgacagcgac agcttttgcg
    10621 tctctagctt ttttagctgt ctagaatgat caatatcact gacctgaatt ggttcgggaa
    10681 tcatttcctt gacctgatcc acaaaggtta accttgcagt caggttctgg tcaaataatt
    10741 gatctgctag cttttctgga gatagagctg tttcttcttc tagattttta gccagtgcta
    10801 ctttcatctt tgattgaaaa gcaaagtcat cttggttaaa attctcggca accttttgag
    10861 cggtctgctc aagcatttga atagattttt tgacagattg ctcaggtgtt acctttagca
    10921 gcttctcaga aaagtaatga gcaaagcttc cattgtgctt catgcgtttt tcgattaagt
    10981 agtaatagcc tgtttgacgg ttaatgacca aggcttcatc aggtgcctga gtagggcttg
    11041 gcaaattatt ttgcgtgatc gtaataggat tttcatgatc gtctgataga tgggcaaaat
    11101 gctcttttag ggcaatgcgt aaaaaggcca gataaggcac tccttcctta tcaaactgaa
    11161 taaaaaccaa atcgtttgtc ttttgatgtt cagaagcgac aaattcttcc ttccaaagct
    11221 tggcaattgt tactgatgtt tccaaaagct ctgtaccgat tgtggtaaaa aaagcatgat
    11281 cagcttctaa ttgcccacgt ttagcgtcgt cagaaaaaac cttggctaat tttttgcgaa
    11341 aatactcatc aattcttggt gttatagcta ctaaagcatc tgataagatc agctcggtat
    11401 cgtttggtgt gaattggtgg atcacaattc cttttatata aatatctagc attgttagtt
    11461 cttcttgtat aatgggaagg cgtcagtcaa tcggcgaacc tcataacgga cctcttcaag
    11521 gatttcaggc tgctggtggt taaccaaggc cttgataatt aaatgagcaa tagtcctact
    11581 ttcgtctact cccattccac gactggtaat ggcagcgcag cctatgcgaa tgcctgatgt
    11641 tttaaaggga gatagggtct caaaaggaat agcatttttg ttaagggtaa tattaacctc
    11701 atcaagcaag gcttgagcaa gcttgccatt ttcaatcacc ttagtcacat caacaaggaa
    11761 aagatggtta tctgtaccgc ctgagatcag acgaaaacga tcatccttgg caaaaacctc
    11821 tgccattgct gctgtatttg ctataacagc ccttgcatag tctgtaaagg caggatcaag
    11881 cgcctcctta aacgcaacag ccttcgctgc tatgacatgc tccaaaggcc caccctgtag
    11941 accagggaaa atagctgcat tcattttcct tgaaattgct tcatcatttg tcaaaagcag
    12001 gccaccacga ggaccacgaa gggttttatg agtggttgag gtcacaatat gagcataagg
    12061 tactggattt tgatgcagac ctgctgcaac caagcctgca atgtgtgcca tatccaccat
    12121 caaataggat cccacctggt ctgcaataaa acgaaattgc tcaaaatcaa tctgccgaga
    12181 ataggctgag gcacctgcaa caatcaactt aggctgaaca gccttagctt gctttaggat
    12241 agctgcgtag tccagctttt cagtttcctt atcgacagtg tagccgacaa attgataggt
    12301 ttttccagaa aaattgacag gtgagccatg tgtcaagtga cctccagctg ccaaatccat
    12361 accaagcaca gtgtcaccag cattaatcag tgccatataa gcagcagcat tggcctgact
    12421 accagaatga ggctgaacgt tggcataggc tgcaccaaag agctttttgg cacgctcaat
    12481 agcaaggctt tcaacaatat caacatactc tgtgccgcca taataacgct tgcttggata
    12541 gccctcagcg tatttgttgg tcaagacaga gccttgtgct tgcataacag cctttgagac
    12601 catattttca gaagcaatta gctcaatatt atgctcttgc ctgtcctcct cggcctgaat
    12661 agcctcccaa agctcctgat catagtcttt gtagttctcg ttgttaaaca tcattattgt
    12721 ctcctctata atagcttcat aaatcgtaat tgtgtcttat catctacata gctcagctta
    12781 cggtaaaagg catgtgcctc ggtcctgtga ctagcagaat taagccgaat aaagcttact
    12841 ttctcctgct tagccttctc ctctaaagca gctagtaagc gacgaccgat acctctacct
    12901 tgatggtcca gcctcactgc taaggccaaa atattaaagc ctttttccga gtaaagcgac
    12961 tcgtagcatt cagcatgcag atagcctaag agcagattgg tcttagtatc agcatagccc
    13021 agcaaataat gatgcttatc ggatcttagt ttttccaatt ggctttttgt caattcaaga
    13081 gaaaccttgt accccaagga ttgatcatta atgtcacaaa tagcttgaca atctgtttga
    13141 tctagtggtc ttagcatagc cttacctcct ctaaaatggc agctctggaa ccttagctaa
    13201 taattgctcc ttagtaatag caccttgtcg taaaatactg accttaggtg acgataaatc
    13261 caaaatagta gaatccttcc ctgtcaaata ggcatcatca gcataaccat caacctttcc
    13321 atcaaatgcc ttgacaatgt cattaaagca ttttccactc tttgagcctg acaggttagc
    13381 agatggccca atcaagggac ccgttgctct gataatttta gctgtgagag ggtgactggg
    13441 tagtcgaaag ccaactgttt ttagcccaga attaatccaa tagggtgtct gggcattggc
    13501 ttttaggata atcgtaagtg gaccaggtaa aaaagcctcg tacagcttgt taagataggc
    13561 aggctgctgc ttagaaaaag ccaaaatact ctcaaaatca gccacattaa ggttcatagc
    13621 cttgtcgcga ggcctttttt tgagacgata aacagcatta acagcctctt catttaaggc
    13681 ctgagcaaaa agaccataaa ctgtctcagt tggtaaaata agagctccac cagccttaat
    13741 tgtctctatc aaatgtgtta tcatcaacaa ccaccattct ttctttaccc agcatatcct
    13801 taagcactct gatacgcttt tgagggaaac gcttggataa gagccttttt aagccttctc
    13861 cctgcttgta gcctatttca aaatagagct taccacttgt cgtcagataa gcactagctt
    13921 gttcgataat gcgtcggtaa atagaaaagc cattttctgc agcaaataag gccaaatgcg
    13981 gctcagattg ataaacattc aagccaacct cgtccttatc ctcataggca atatagggag
    14041 ggttagaaac aatgatgtca aactgccctg atagcttgct aaaaaggtct gactgctcaa
    14101 aggctatctc tacatgatga tctaaagcgt ttgagtaagc aaggctcaag gcatcagctg
    14161 aaatatcaga ggctgtgacc tgccagttag gtcttgcttt ttttaaagca attgcaatag
    14221 caccactgcc tgttccaatg tctaaaacgg atttgcgagt agcgtcattt tccttcaaga
    14281 taagctcaac taattcttcc gtctctggtc ttgggattag cacgcgcgaa tccactgcaa
    14341 gcaccagatc tctaaaataa gccctgcctg tgatatattg tggcgataca tgctggctaa
    14401 gcgctaaaaa aatccgctct aataaggctt gatcctctga agtgacctct tgattttgat
    14461 gaagcaaaaa gtcaaggctt gtccactgct ttaattcttt aaaaacatag gcgaggtttt
    14521 cacgatcctc acctatgttt tctagcctgt cttcgtaggc tcttagttgc ttagcatagt
    14581 tcattggtta tttagcgatt ctaatttctg agtttgatca tatagcacta aagcgtcaac
    14641 aatctcgtct aactttccag acaaaatggt gtctaatttt tgcagggtta gaccgatacg
    14701 gtgatctgtc acacgatttt gtgggaaatt ataggtccga atccgttcag aacgatcacc
    14761 cgtaccgata gttgatttac gctctgcgtc ctgctcgtcc tgtgcgatct gtgcaaaatg
    14821 atctgctaca cgtgcccgaa taatcttcat agccttgtca cgattctttt gctgcgttct
    14881 ttcctcttgc atctcaacct tgatgtttgt tgggagatgg acgatacgaa cagcggttgc
    14941 caccttgttg acattttgtc cgccagcacc agaagcatgg taaatatcaa tacgaaggtc
    15001 ctttggatca atgtcgtact caacttcttc tacctctggc atgactaaga cagtcgcagt
    15061 tgaagtatgc acgcgccctt ggctttctgt tacaggaaca cgctgtacgc gatgagcacc
    15121 tgattcgtat tttagcttgg aataaacaga ttgtcctgaa accatagcaa caacctcttt
    15181 aatccctcca acaccattat aggaagcctc cattacctca aagcgccagc cttggctttc
    15241 ggcaaatttt tggtacatgg ctaagagatc accggcaaat agagcagcct catcaccacc
    15301 tgcggcacca cgaatttcca agataatatt tttatcatca tttggatctt tgggaagcag
    15361 caaaagcttt aacttgtcct cataggcttc cttggcagac ttggcctctt ttagctcctc
    15421 cttggccatc tcttcaatgt caggatcgcc gccggcttcc ttaatcatct cctcagcgtc
    15481 atcaatggat tggataatag ccttatactg acgataagct gctactgttt ctcgtgtgct
    15541 agcctcttcc tttgacagag ccataaaacg tttggtgtca gaaacaacct ccggatcact
    15601 taataattcg cctaattctt cataacggtc ctcaacggcc tgtaattgat cataaatatt
    15661 cattaggggg tattctctcc tctttttact tgttttagtt gttattagat tggtgggtga
    15721 aaataatgct tgcgacaaac tggaatatag gtctcattgc caccaatttg aatctgtgct
    15781 ccctcataaa cgggcttacc atgttctgtt cgcaatacca tagttgcttt tttgctgcaa
    15841 tattgacaga tggtttttat ctcatcaatc ttatcagcta acagtaacag gtatttggag
    15901 ccttcaaaca attcattttg aaaatcattt tttaagccaa aggccatcac tggaacattt
    15961 agctcatcaa ccacacgtgc taaatcatag acattttgct tgcttaaaaa ttgacattcg
    16021 tcaatcaaga cgcaataggg cttctcctgc aattcagcaa taaatgcaaa aatatccata
    16081 tcattcgaaa ttggtacagc ctcacgacgc atgccaatcc gactagaaac aatgccaaag
    16141 ccatcacgtg tgtctagcgc acttgtcata atcacaacag gcttcccctg ttcttcataa
    16201 ttgtgtgcta ccttcaagat ttcaatggtc tttcctgaat tcattgttcc atatttgtaa
    16261 tataattgag ccaaaatgga gattcctacc ttcttctttt gtcctactta ttctatcata
    16321 tttgtcccta tttggcgatt gccttatctg aaaatcttat tttcacaaca gctaaatcct
    16381 gtgctgttga gctaaggtta ggctttttga agctgacatg ctacaataga ggtatcatta
    16441 aaaaaaggag attgactatt atgccatttg taacgattga cctgtttgag gggcgtagcc
    16501 aagaacaaaa aattgcccta gcgcgtgagg tgacagaggt tgtttctcgt atcgcacagg
    16561 ctccaaaaga agcgattcat gttgtaatca atgacatgcc tgaggggacc tatttcccgc
    16621 atggtgagat gaaaaccaaa gcctaatgcc taagtcccac ttatctaggt gggcttttcc
    16681 tatttgaaaa ggagggcctg atgatagcta ctgatcagat caagatgatg ggaacaatca
    16741 ttgatatttg cattgactca tcaaaagcaa agcagcaagc agctactatc cgagagctac
    16801 taacccttta caatcaccgt ttttcggcca gtgacgacag ctctgaatta atggcaatca
    16861 accatatggc aggtattcag ccagtgcgtg tgcattcaga tttgtttgac ttaatctcaa
    16921 tcggaaaaga gcatagcttg gcttatccaa gcaaccttaa tatcacactt ggtcctttag
    16981 tgcaaagctg gcgcatcggc ttttcagacg ctaagcttcc agatgaagca actattgatc
    17041 gcagactaag actaaccaat cctaatcata tcatc
//
LOCUS       DARYXW010000045        17015 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.045, whole genome shotgun sequence.
ACCESSION   DARYXW010000045 DARYXW010000000
VERSION     DARYXW010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17015)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17015)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17015
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.045"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(220..1944)
                     /gene="ezrA"
                     /locus_tag="TV191_001182"
     CDS             complement(220..1944)
                     /gene="ezrA"
                     /locus_tag="TV191_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEL1507700.1"
                     /translation="MSSGIILLIVAIVLLVIIAYLVGVIIRKRNDTLITSLEERKQAL
                     FGLPVNDEIEEVKSLHLIGQSQTSFREWNQKWVDLTLNTFTDIEKHIFEAEHLNDTFN
                     FIRAKHEINSVESQLNLVEEDITAIREALGILKEQEEKNSARVTHALDLYEKLQASVA
                     ENEDNFGSTMAEIEKQMKNIEAEFSQFVALNSSGDPVEAAEVLDKAEEHTIALGQITE
                     QIPAIVAKLEDDFPDQLDDLETGYRRLLEENYHFPEKNIEARFQEIRESIRANSSELV
                     TLDLDRARDENTHIQERIDSLYELFEREIAAYKVVAKNSKILPRYLAHAKHNNEQLKH
                     EIARLSRKYILSENEGLNIKAFDKDLKDIEDNVLEIAEAFDQQEKPFSELQLILDRSI
                     KTLASVESGQMDVFAAVKDIEKIESQARQHLEIYVTQLHMIKRYMEKRNLPGIPQDFL
                     STFFTTSSQLEALMDELSRGRINIEAVSRLSEVATAAIANLEELTYQVVQHATLTEQL
                     LQYSNRYRSFEAGVQNSFEHALKLFEVDNDYQASFDEISYALETVEPGVTERFVNSYE
                     KTRERIRF"
     gene            complement(2093..4045)
                     /gene="gyrB"
                     /locus_tag="TV191_001183"
     CDS             complement(2093..4045)
                     /gene="gyrB"
                     /locus_tag="TV191_001183"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEL1507701.1"
                     /translation="MVEENKQLEDKAQEYDASQIQVLEGLEAVRMRPGMYIGSTAKEG
                     LHHLVWEIVDNSIDEALAGFASHIQVFIEADNSITVIDDGRGIPVDIQAKTGRPAVET
                     VFTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVRVYKNGHIHYQEFRRGAVV
                     DDLAIIGTTDVTGTTVHFTPDPEIFTETTEFDYQVLAKRIQELAFLNRGLKISITDKR
                     AGLEREEHFHYEGGIGSYVAFLNDKKDVIFDTPIYSDGELEGITVEVAMQYTTGYHET
                     VMSFANNIHTHEGGTHEQGFRTALTRVINDYAKKAKILKENEDNLTGEDVREGLTAVI
                     SVKHPNPQFEGQTKTKLGNSEVVKITNRLFSEALQRFLLENPQVARKIVEKGILASKA
                     RIAAKRAREVTRKKSGLEISNLPGKLADCSSNDASQNELFIVEGDSAGGSAKSGRNRE
                     FQAILPIRGKILNVEKATMDKILANEEIRSLFTAMGTGFGAEFDVSRARYQKLVIMTD
                     ADVDGAHIRTLLLTLIYRFMRPVLEAGYVYIAQPPIYGVKVGSEIKEYIQPGVNQEEE
                     LKAALERHSTGRSRPTIQRYKGLGEMDDHQLWETTMDPDNRLMARVTVDDAAEADRIF
                     DMLMGDRVEPRREFIEENAVYSTLDI"
     gene            complement(4046..4615)
                     /locus_tag="TV191_001184"
     CDS             complement(4046..4615)
                     /locus_tag="TV191_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEL1507702.1"
                     /translation="MKVMNYHDYIWDLGGTLLDNYEISTQAFIETLHFFKLSASHDAV
                     YQRLKKSTATAIQVFAPNEPQFLQYYKANEAKKLANPIWCLGAKDILKRIVASGSRNF
                     LISHRDHQVNDLLEQAGLLGYFTEVVTASNGFARKPNPESLLYLKEKYLISKGLVIGD
                     RRLDIEAGQAAGFDTLLVDGRKNLLEIVD"
     gene            complement(4711..5925)
                     /locus_tag="TV191_001185"
     CDS             complement(4711..5925)
                     /locus_tag="TV191_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEL1507703.1"
                     /translation="MLPKRKLIDQRLDYAIIFPVFCLLIFGLVSVYVAASHDFPQSLA
                     TVMLQQVLWILLGAVIAFTLMFFSTEILWKLTPVFYLLGVLLMVLPLIFFSPRLVAAT
                     GAKNWITIGSTTLFQPSEFMKISYILAMSWLTVWFKRKQERSRFLDDWKLLGLYLVLT
                     LPVMVLLALQKDLGTAMVFLAILAGIILISGISWWLILPALVLVFLLVSAFFFVFLLP
                     EGKEFLLKMGMDTYQLNRISAWLTPFDFSDTIAYQQTQSMISIGSGGFFGKGFNQLEL
                     SVPVRESDMIFTVIAENFGFLGAASLLILYLILIYRMLRVTFASNNLFYTYISTGFIM
                     MILFHIFENIGAAVGLLPLTGIPLPFISQGGSSLISNLIGVGLILSMNYQHVLAHEKQ
                     SEHELSRSSRYV"
     gene            complement(6578..8005)
                     /locus_tag="TV191_001186"
     CDS             complement(6578..8005)
                     /locus_tag="TV191_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019322885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEL1507704.1"
                     /translation="MAKQYKNLVNGEWKLSENEIKIYAPATGEELGSVPAMSREEVDQ
                     VYASARAALADWRALSYVERTAYLHKAADILVRDAEKIGAVLSKEVAKGYKAAVSEVI
                     RTAEIINYAAEEGLRMEGEVLEGGSFEAASKKKIAIVRREPVGLVLAISPFNYPINLA
                     GSKIAPALIAGNVVVLKPPTQGSISGLLLAEVFAEAGLPAGVFNTITGRGSVIGDYIV
                     EHEAVNFINFTGSTPIGERIGKLAGMRPIMLELGGKDSAIVLEDADIALAAKNIVAGA
                     FGYSGQRCTAVKRVLVMESVADQLVAEIKGLVEKLLIGMPEDNADITPLIDTKAADFV
                     EGLVNDAADKGAQALTEIKRDGNLICPILFDRVTTDMRLAWEEPFGPVLPVIRVSSVE
                     EAISISNQSEYGLQASIFTTNFPQAFAIAEKLEVGTVHINNKTQRGTDNFPFLGAKKS
                     GAGVQGVKYSIEAMTSLKSVVFDIQ"
     gene            complement(8207..9940)
                     /gene="ptsP"
                     /locus_tag="TV191_001187"
     CDS             complement(8207..9940)
                     /gene="ptsP"
                     /locus_tag="TV191_001187"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEL1507705.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DVALQASQDELSVIREKAVESLGEEAAAVFDAHLMVLADPEMISQIKETIRAKQTNAE
                     TGLKEVTDMFITIFEGMEDNPYMQERAADIRDVAKRVLAHLLGVKLPNPATIDEEAIV
                     IAHDLTPSDTAQLNKQFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNDITKRVKDGD
                     LIAVNGITGEVIIDPSEEQILAFKEAGEAYAKQKAEWALLKDAQTVTADGKYFELAAN
                     IGTPKDVEGVNDNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDLPKEMNPFLGFRALRISISETGNAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKVVFEEEKASLLSEGVAVADDIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDSAKMAEYAHRALTECSTAEEV
                     LELAKEYITEA"
     gene            complement(9945..10208)
                     /locus_tag="TV191_001188"
     CDS             complement(9945..10208)
                     /locus_tag="TV191_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEL1507706.1"
                     /translation="MASKDFHIVAETGIHARPATLLIQTASKFASDITLDYKGKAVNL
                     KSIMGVMSLGVGQGADVTITAEGADADDAIAAIEETMTKEGLA"
     gene            10630..10848
                     /gene="nrdH"
                     /locus_tag="TV191_001189"
     CDS             10630..10848
                     /gene="nrdH"
                     /locus_tag="TV191_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEL1507707.1"
                     /translation="MITVYSKHNCMQCKMTKKFLEQHGAAFQEINIDEHPEKVDYVKS
                     LGFTAAPVIETEQIVFSGFQPAKLKDII"
     gene            10869..13028
                     /gene="nrdE"
                     /locus_tag="TV191_001190"
     CDS             10869..13028
                     /gene="nrdE"
                     /locus_tag="TV191_001190"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEL1507708.1"
                     /translation="MSLKDLGDISYFRLNNEINRPVDGSIPLHKDKEALEAFFTENVI
                     PNTMSFSSINEKIAYLVDNDYIESAFIQNYSPEFISHLAKSIQAEGFRFKSFMAAYKF
                     YQQYALKTNDGNFYLESIEDRVMFNALYFADGDETLAKDLAIEMINQRYQPATPSFLN
                     AGRSRRGELVSCFLLQVTDDMNAIGRSINSALQLSRIGGGVGISLSNLREAGAPIKGY
                     AGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLSVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGITVPDKFYELARHNADMYLFSPYSVEREYGLPFNYIDITSMYDELVANPNI
                     TKTKIKARDLETEISKLQQESGYPYVINIDTANRSNPIDGKIIMSNLCSEILQVQTPS
                     LINDAQEFVKMGTDISCNLGSTNILNMMTSPDFGRSIRAMTRALTFVTDSSNIEAVPT
                     VKNGNSQAHTFGLGAMGLHSYLAQHHIEYGSPESIEFTDIYFMLMNYWTLVESNQIAR
                     ERQTTFVGFEKSTYASGAYFDQYITGECVPKSELVKSLFKDHFIPQAADWKALRQAIM
                     TDGLYHQNRLAVAPNGSISYINDCSASIHPITQRIEERQEKKIGKIYYPANGLSTDTI
                     PYYTSAYDMDMRKVIDVYAAATKHVDQGLSLTLFLRSELPKELYEWKTESKQTTRDLS
                     ILRHYAFNKGIKSIYYIRTFTDDGEEVGANQCESCVI"
     gene            13173..14132
                     /gene="nrdF"
                     /locus_tag="TV191_001191"
     CDS             13173..14132
                     /gene="nrdF"
                     /locus_tag="TV191_001191"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEL1507709.1"
                     /translation="MTTYYEAINWNEIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RRLSAVEKDLVGKVFGGLTLLDTMQSESGVEAIRKDVRTPHEEAVLNNIQFMESVHAK
                     SYSSIFSTLNTKKEIEDIFEWTNNNVFLQNKAKIINDIYENGSALQKKVASTYLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELSESEQESLR
                     DWMYDLLYQLYENEEQYTKTLYDEVGWTEEVMTFLRYNANKALMNLGQDPLFPDTAND
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGTVEAMTDDDYNYGL"
     gene            14218..15474
                     /locus_tag="TV191_001192"
     CDS             14218..15474
                     /locus_tag="TV191_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEL1507710.1"
                     /translation="MITRLITFLTWTGQLVVAGVIAGVVAYVLTQAIHFIQAISFGYQ
                     SGSFSTMIATVAPERRFLSLLLAGAIAGLGWQLLAKKAKPIQPIQQTLSQQKDFSPWT
                     QFCHGWLQLITVSMGAPVGREGASREVAVALTAACNKAINASAAEQGLLLACASGAAL
                     GAVYQAPLATIVFIMEAIVKKCSVKHIYAAAITAFTAVQSVLVLSGHQDIQYLILPQA
                     WQLTTVLWAIIASPILAFLAFCYQQLLQNAPKAKPKSRWFIPRVLGAFGFSACLSLYF
                     PEILGNGKAGLLLLLHHDVSLSYTASLLLSKAAAVYAVFASGAKGGKIAPSMMLGGAS
                     GLLLASLSNQLGYLSVPLPLAIVIGATLFLGIINQIPLTAPLFLIEITGQPLISLVPL
                     AIVGLTSYLSQQLFQKSLFFNKHKKL"
     gene            complement(15543..16319)
                     /locus_tag="TV191_001193"
     CDS             complement(15543..16319)
                     /locus_tag="TV191_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEL1507711.1"
                     /translation="MKAFMTEKDSTLVRILKSLLLGSGIGLVLGGLVGFGLARFNILE
                     NGFPISEEDTITGIKWGMRPLVIVLMLLSIYDIYQVVKEYARYVKLSDDETEELYRYI
                     NLKHAYALGFSAMAMVLNIVVFSLGYRVPIANNASYLGLTFPIYEALMLVVISVLHAY
                     ILKVYTRIRGVKMTLAPTLKELKQNILQQDEAELQANYQMSFEVVMGLSGFILPGIYV
                     ILLLLSMIFQRVELTGLIITASIHLYILVKSFKSAHDFYR"
     gene            complement(16316..16531)
                     /locus_tag="TV191_001194"
     CDS             complement(16316..16531)
                     /locus_tag="TV191_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1507712.1"
                     /translation="MAYRLRNRLKELRARDGINQTQMAALAGVSRQTISLIERNEYTP
                     SIIIAMKIAKVFNEPIEQVFSLVEGER"
BASE COUNT         5003 a         3933 c         3204 g         4875 t
ORIGIN      
        1 aaatggataa tcgtctgatt ttattacaaa atatctcatg tagcaacagc ccaatagcac
       61 taaggccttg tctatctcta ctgactggct tgaaccagct ttttgggtat agctcaagga
      121 ggccatagcc tgaccattca aaaagcttga aaaagcatag cccagcatgg actgcttttt
      181 caagcttttt cgtaatataa agtatcaacc cttgtcacat tagaagcgga tacgttcacg
      241 tgtcttctca taggaattga caaaacgctc tgtcactcct ggctcgactg tctccaaggc
      301 ataggaaatc tcatcaaatg atgcctgata gtcattgtcc acctcgaaca atttcaaggc
      361 atgctcaaag ctattttgca cgccagcttc aaaggaacga taacggttag agtactggag
      421 cagctgctct gtcaaggtag catgctgaac cacttggtag gttagctctt ctagattagc
      481 aatagcagct gttgccacct cagacagacg ggacaccgct tcaatgttga tacgtcctct
      541 acttagttcg tccatcaatg cttctagctg cgaactagtg gtaaagaagg tactcagaaa
      601 atcctgtgga attcccggta aattgcgctt ttccatataa cgcttaatca tgtgaagctg
      661 tgtgacgtag atttctaagt gctggcgagc ctgtgactca atcttttcaa tgtctttaac
      721 agcagcaaag acgtccatct gaccagactc tacagaagcc aacgtcttga tactacgatc
      781 aagaatcagc tgtagctctg aaaatggctt ttcctgctga tcaaaggctt cagcaatctc
      841 aaggacattg tcttcgatat ctttgaggtc tttgtcaaag gccttgatat ttaagccttc
      901 attttcactc aagatatact tacgtgatag acgagcaatc tcatgcttca actgctcgtt
      961 gttgtgcttg gcgtgagcca ggtatcttgg taatattttg ctatttttag caaccacctt
     1021 gtaggctgca atctcacgct caaagagctc atacagtgag tcgatacgct cttgaatgtg
     1081 agtattttca tctctagctc ggtccaaatc aagggtaacc agctctgatg aattggcacg
     1141 aatagactca cgaatctctt gaaagcgggc ttcaatattt ttttctggga agtgataatt
     1201 ttcctccagc aaacgacgat agcctgtctc cagatcgtcc aattgatccg gaaaatcatc
     1261 ttcaagcttt gctacaatag cagggatctg ctctgtaatt tgccccaagg caatcgtatg
     1321 ctcctcagcc ttatccaaaa cctccgctgc ttcaacaggg tcacctgatg aattaagggc
     1381 aacaaattgt gaaaactctg cttcaatatt cttcatttgc ttttcaattt cggccattgt
     1441 tgatccgaaa ttatcttcat tttcagcaac ggaagcctgc aacttttcgt acaaatctag
     1501 tgcatgagta acacgcgcgc tgtttttttc ttcctgctcc tttaatatgc caagtgcttc
     1561 acgaatagcg gtaatatcct cttcaacgag attcaattga ctctcaacgc tattaatctc
     1621 atgcttggca cgaatgaaat taaaggtgtc atttaagtgc tcagcctcaa agatatgctt
     1681 ttcaatatcg gtaaaggtat ttagggtcaa atcaacccac ttttgattcc attcacgaaa
     1741 tgaggtctgg ctttgaccaa tcaagtgaag agacttgact tcctcgattt cgtcattaac
     1801 aggaaggcca aataaagctt gttttcgttc ttctagactg gtaattaatg tgtcattacg
     1861 cttgcgtata ataacaccca ctaaataagc aataatcact agtaagacta tggccacaat
     1921 cagcaagata attccgcttg acatcttaat ctccttatta tttagatgcg attgatcaac
     1981 tgccggttca gtaggaacaa ctagcaagaa tcgcctttta ttatattatc aaaaatacac
     2041 tataacgtta cgattataac atacttttag gtgcttttca aaatatattt gactaaatgt
     2101 caagcgtact atagaccgca ttttcctcaa taaattcacg ccttggctca acacgatcgc
     2161 ccatcagcat gtcaaaaatc cgatcagcct ctgccgcatc atctacggtc acacgtgcca
     2221 ttagacgatt atcagggtcc attgttgttt cccaaagctg gtgatcgtcc atctctccta
     2281 ggcccttata gcgttgaata gtcggccttg agcgtcctgt gctatgtctt tcaagagcag
     2341 cctttagctc ctcttcttgg ttgactcccg gttgaatgta ttccttaatc tcgctgccaa
     2401 ccttaacacc ataaatcggt ggctgagcaa tgtaaacata gccagcctct aatactggtc
     2461 gcatgaagcg ataaatcaac gttaacaaaa gcgttctgat atgagctcca tcgacatctg
     2521 catcagtcat gatgaccagc ttttgatagc gagctctaga aacatcaaac tccgctccaa
     2581 agcctgtccc catagcagta aagaggcttc tgatttcttc gttagcaagg attttatcca
     2641 tcgttgcttt ttcaacgttt aaaattttac cacgaatagg cagaatagcc tgaaactcac
     2701 gattgcgacc tgacttcgct gatccaccag ccgaatcccc ctccacgata aaaagctcat
     2761 tttgactagc atcatttgag gagcagtcag ccagcttccc tggcaaattg gaaatctcta
     2821 ggcctgattt tttgcgggtt acttcacgcg ctctcttggc agcaatgcga gccttagagg
     2881 ctagaatccc cttttcaaca atcttacggg caacctgcgg attctctagt agaaagcgct
     2941 gaagagcttc gctaaacaag cgattggtaa tcttaacaac ctcagaattt cctaactttg
     3001 tctttgtttg cccttcaaat tgtggatttg ggtgcttgac agaaataaca gcagtcaagc
     3061 cctcgcggac gtcctcacct gtcagattat cctcgttttc cttgagaatc ttagccttct
     3121 tagcatagtc attaatcacg cgcgtcagag ctgttctaaa gccctgctca tgggtaccac
     3181 cctcatgtgt gtgaatattg ttggcaaagc tcataacagt ctcatggtaa cctgtagtgt
     3241 actgcatcgc cacctcaact gttatcccct ccagctcacc atcagaataa atcggagtat
     3301 cgaagatgac gtcctttttg tcatttaaaa aggcaacata agagccaata ccaccctcgt
     3361 aatggaaatg ctcttctctt tcaagaccag ctcgtttatc tgtaattgag atttttaagc
     3421 cacgattaag aaaggccagc tcttgaatac gctttgccag gacctggtag tcaaattctg
     3481 ttgtttctgt aaagatctct ggatcaggtg tgaaatgcac tgttgttccc gtaacatcag
     3541 tcgttccaat gatagccaaa tcatcaacta cagcaccacg cctaaactcc tgatagtgga
     3601 tatgcccatt tttatagaca cgaacatcaa gctgtgtgga taaggcatta acaaccgagg
     3661 agccaacacc atgaagtcct ccagaaacct tgtagccacc accgccaaat tttccaccgg
     3721 catgcaaaac tgtaaaaact gtctctacag caggccggcc tgtcttagct tgaatatcaa
     3781 ctgggatacc acgtccatca tcaataacgg taatcgaatt atctgcctca ataaaaacct
     3841 gaatatgact ggcaaagcct gccaaggctt catcgataga attatcaaca atctcccaaa
     3901 ctaggtgatg taagccttcc ttggcagttg agccaatata cattccagga cgcatgcgaa
     3961 cggcttctaa cccctctaag acctgaatct ggctagcgtc atactcttga gccttgtctt
     4021 ctaattgttt attttcttca accatctaat ctactatctc caataggttt tttctaccat
     4081 caacaagcag ggtgtcaaag cctgctgctt gtcctgcttc tatatcaagt ctgcgatcac
     4141 caatcactaa gcccttgctg atcaggtact tttccttcaa ataaagtaag ctctcagggt
     4201 taggctttct ggcaaagcca tttgaggcgg taacaacctc ggtaaaatag cccaaaagcc
     4261 cagcctgctc cagcaaatca ttgacctgat gatcacgatg ggatattaaa aaattacgcg
     4321 agcctgatgc cacaatcctc tttagaatgt cctttgcacc taggcaccaa ataggattgg
     4381 ctaatttctt agcctcattc gctttgtaat attgtaaaaa ttgcggttcg ttgggagcaa
     4441 atacttgaat ggcggttgct gttgatttct taagcctttg ataaacggca tcgtggcttg
     4501 cagacagctt aaaaaaatgc agcgtctcaa taaaagcctg ggtagaaatt tcatagttat
     4561 ccaagagagt gccgcccaaa tcccaaatat aatcatgata attcataacc ttaattataa
     4621 catatttttc tttattttta tagcgattaa gcaaataaaa aagggttgat tggcagctca
     4681 ttctaaccga acaaggacca aacatgcctc ttaaacataa cgtgagcttc tgctaagctc
     4741 atgctcgctt tgcttttcat gagcaaggac gtgctgatag ttcattgata ggatcaggcc
     4801 gaccccaatc agatttgaaa tcaaggaaga gccgccctga gaaataaagg gaaggggaat
     4861 accggtcaaa ggtagcagac caactgctgc gccaatgttt tcaaaaatat gaaatagtat
     4921 catcatgata aagccggttg aaatgtaggt ataaaaaagg ttattcgatg caaaggtcac
     4981 cctaagcatg cggtaaatca gtattaaata caagatcagt aagctagctg caccaagaaa
     5041 gccaaaattt tcagcgatca ctgtaaaaat catatcactt tctctgactg gtactgacag
     5101 ctcaagctga ttaaagccct taccaaaaaa gccaccactc ccaatcgaaa tcatactttg
     5161 cgtctgctga taggcaatgg tatctgagaa atcaaacggt gtcagccaag ctgaaatacg
     5221 attcaattgg taggtatcca ttcccatttt taaaaggaat tcttttccct ctggcaacaa
     5281 aaaaacaaag aaaaaagctg aaaccagtaa aaagactagt accaaagctg gtaaaataag
     5341 ccaccaagaa attcctgaaa ttaagataat cccagctaag atggctaaaa aaaccatagc
     5401 tgttcctaag tccttttgca gtgctagcag gaccatgacc ggcaacgtca agacaaggta
     5461 taagcccaag agcttccaat catctaaaaa ccgacttctc tcctgctttc tcttaaacca
     5521 gaccgttaac caagacattg ccagaatgta ggatattttc ataaattctg atggttgaaa
     5581 caaggtcgtt gagccaatcg taatccaatt tttcgcccct gtagcagcta ccagccgagg
     5641 gctaaaaaag atgagtggca gaaccattaa tagcacaccc aaaagataaa agacaggtgt
     5701 taatttccac agaatctctg tgctaaaaaa cattagggta aaggcaatca cagctccaag
     5761 aaggatccag agaacctgtt gaagcataac agtggcgagg ctttgcggaa aatcatgact
     5821 tgctgccaca tatacagata ccagaccaaa tattagcaaa caaaaaacag gaaaaataat
     5881 ggcataatca agacgttgat caattaattt tctcttgggt aacatgatgt cctactttct
     5941 aaacaaggaa gctagcagtc taaaccatta gtctacataa aaaaagaagc aaggagctct
     6001 agagatgacc accgcaggtc atcacccctc aatcccagcc ctctatcaag gcaagtaaag
     6061 caagccatta gtcctcttgc aaagatacca aagcctatat gagttttcat aagatctcat
     6121 acacttcact aaaagaagca agaagcatag ccacagcctt tgcctctaag ccttttgtgg
     6181 acaaggagac aactaaatcc aacagctatc tcacagctca agaggcagac cgacaagtag
     6241 ctctagtatt catattataa tggaaagccc tcaaaatagc aatgatagat attaagcctt
     6301 tcaccaagct tttgaaccat cagctatttt agcagcttcc ttgacctcaa tggctagtcc
     6361 tgctggctgt tggcgagact ttgtacactc acatcttaag gagatcaaaa cactctaaac
     6421 ttttttacga ccccaaaatc attaaatatt tagatctcat ctttgaggtt gggacaactc
     6481 accttcttgc atagctagct gttaaaacta gagacacaaa taaaacagcc gcacaaatgt
     6541 gcaactgctt tcaaactaag ataccctagc ttttttgtta ttgaatatca aatacgactg
     6601 atttgagact tgtcattgcc tcaattgaat atttgacccc ttgaacacca gctcctgatt
     6661 tcttagcccc taggaatggg aaattatctg taccacgttg ggttttgttg ttaatgtgta
     6721 ctgtaccaac ctcaagcttc tcagcaatag caaaggcctg tggaaaatta gtcgtaaaga
     6781 tagacgcttg caaaccgtat tcagattgat ttgaaatgct gattgcctct tctacagagc
     6841 ttacacgaat cactggcagc accggaccaa atggctcctc ccaagccaag cgcatatcag
     6901 ttgttactct atcaaacaag ataggacaaa ttaaattacc gtcacgcttg atttcagtaa
     6961 gcgcctgtgc tcccttgtct gctgcatcat taaccagacc ttcaacaaaa tctgccgctt
     7021 tggtatcaat caatggtgtg atgtcagcat tgtcctctgg cataccgata agtaatttct
     7081 caactaagcc cttaatctct gctaccagct ggtctgcaac gctttccata acaagcacac
     7141 gcttaactgc tgtacagcgt tgacctgagt agccaaaggc acctgcaaca atgtttttag
     7201 cagctaaggc aatatcagca tcttctaaga caatcgctga atccttacca ccaagctcaa
     7261 gcataatcgg acgcatgccg gctaatttac caattcgctc tccaattggc gttgagccag
     7321 taaagttgat aaagtttaca gcctcatgct caacgatgta atcaccaata actgagccgc
     7381 gtccagtgat ggtattaaag actccagcag gaagacctgc ttctgcaaat acctctgcta
     7441 agagcaagcc agaaatagag ccttgtgtcg gcggcttaag aaccacgaca tttcctgcaa
     7501 taagggctgg agcaatcttt gagcctgcta ggttaatcgg ataattgaag ggtgaaatcg
     7561 caagcacaag tcccactggc tcacgacgta cgatcgcaat ctttttctta ctagcagcct
     7621 caaagctgcc accctcaagg acctcgcctt ccatacgaag gccttcttct gctgcatagt
     7681 taataatttc tgctgtacga ataacctcac taacagcagc cttataaccc tttgcaacct
     7741 cttttgagag aacagcacca atcttctcag catcacgcac caaaatatca gcagccttgt
     7801 gcaaataagc agtacgctca acataagaaa gcgctctcca atctgcaaga gcagcgcgag
     7861 ctgacgcata aacctgatca acctcttcac gagacatagc tggtacacta cctaactcct
     7921 cgccggttgc tggtgcatag atcttgatct cattttcaga gagcttccac tcaccattca
     7981 ctaaattttt atattgttta gccaaacttt tttctccttt tataatggta ctattattct
     8041 atcacttttt tagcatattt caacaattcg ctacaggaag agtctgaaaa ttctgataaa
     8101 acttgaaaca tcaaactact ttataaagca agctttcata tggatctgat tagtcatttt
     8161 tctagtaaaa aagagccgga caaaaccagc tcctcgttat ttctatttaa gcttctgtaa
     8221 tatactcttt ggcaagctca agaacctctt cagcagttga gcattctgtg agtgcacgat
     8281 gagcatactc tgccattttc gctgaatcaa gctttttcat caggctacgt gtgcgaagca
     8341 cagatgttgc tgacattgaa aattcatcaa gccccatacc aacaagaagc ggcacagcct
     8401 gttggtcacc tgccatttca ccacacatac cagcccactt accttcagca tgagctgctt
     8461 tgataacatt gttaatcaaa cgaaggattg atgggttata tggctggtaa aggtatgaca
     8521 cttgctcgtt catgcggtct gctgccattg tgtactggat aaggtcattt gtaccaattg
     8581 agaagaagtc aacctccttg gcaaattggt cagcaagcat tgctgctgct gggatctcaa
     8641 tcatgatacc aacctgaata tcgtctgcaa ccgcaacacc ctcagacagc aagctagcct
     8701 tttcttcttc aaatacgact ttagcagcac gaaattcctt tagaagggca accatcggga
     8761 acatgatacg caattgacca tgcacagaag cacgcagcaa agcacgaatt tgtgtgcgga
     8821 acatagcatt acctgtttca gagattgaaa tgcgtaaggc acgaaaacca aggaatgggt
     8881 tcatttcctt tggtaaatca aagtaaggaa gctccttgtc cccaccgata tccattgtac
     8941 gaacaacaac aggcttgccg ttcattcctt caagaacagc cttgtaggct tcatattgct
     9001 catcttcggt tgggaaatcc tgagaatcca tataaagaaa ctcagtacgg taaagaccta
     9061 ccgcctcagc accattatcg ttgacacctt caacgtcctt aggtgtaccg atgtttgctg
     9121 ctaattcaaa gtacttgcca tctgctgtga cagtttgtgc gtccttaagc agagcccact
     9181 cagccttttg cttcgcataa gcctctccag cttccttgaa agcaagaatc tgctcctcac
     9241 ttgggtcaat aataacctca ccagtgatac cattaacagc aataaggtca ccatctttga
     9301 cacgcttagt aatatcattt gtaccaagca cagccgcaat ctcaagtgta cgggccatga
     9361 tagccgaatg actcgtacgt ccgccaatgt tcgttacaaa tgcttttaca aattgtttgt
     9421 taagctgtgc agtatctgaa ggagtcaaat catgtgcaat aacaattgct tcttcatcaa
     9481 ttgtagctgg atttggaagc ttaacaccta ataaatgagc caagacgcgc ttagcgacat
     9541 ctcgaatatc agccgcacgc tcttgcatat aaggattgtc ttccatgcct tcaaagattg
     9601 tgatgaacat gtcagtcact tcttttagac ctgtttcagc attcgtttgc ttcgcacgaa
     9661 tagtctcttt aatttggctg atcatctctg gatcagcaag aaccattaaa tgggcatcaa
     9721 aaactgctgc cgcttcttcg cctaggcttt ctactgcttt ttctcggata acagaaagct
     9781 cgtcttgtga agcttgtagt gcaacatcaa ggcgagcttc ttctgcattt gtatcctcga
     9841 ctgtgatagt ctcaaatgac aaatccggct gaactagcag atatgctttg gcaacagcaa
     9901 caccgtcaga ggctgcgatt cctttaagca tttctgtcat agtcttatgc caatccttct
     9961 ttagtcatag tttcttcgat tgccgcaata gcgtcatctg catcagcgcc ttctgctgtg
    10021 attgttacgt cagcaccttg accaacacca aggctcataa cacccatgat tgatttaaga
    10081 tttactgctt tacctttgta gtcaagtgta atatctgaag caaatttgct tgctgtttga
    10141 ataagtaagg tagctgggcg tgcatgaata cctgtttctg caacaatgtg aaagtctttt
    10201 gaagccataa tatggttctc cttttgaatt gtgtattttc gagctatcac atgataaccc
    10261 ttacaataag tgattatagc acaatgcttt tttattttca aggttaaatg ttctaacaag
    10321 aaaaaatcat gaaacagttt tcttgtattt tcatttgttg tcaatatttc ttacatgatg
    10381 attttcataa tgtcaaataa gccttccaac ctgattagta tgcatttaag aactacaagc
    10441 ctcttgtagc aattatcagt gataagagag gataacacaa tatttagaaa tattctcaca
    10501 cacaaccaca atatcttgtg ctattctgaa ataaatcgtt tgctttttag gaacattttt
    10561 tatatcctat tagagtcatt tgatttttcc taaaattgag tgaaagacta atagttggaa
    10621 ggacgagcaa tgattacagt atactcaaag cacaattgca tgcagtgcaa aatgactaag
    10681 aaatttttag aacagcatgg agctgctttc caagagatta atattgatga gcatccagaa
    10741 aaagtggact atgttaagag ccttggcttt actgctgctc ctgttattga gacagagcag
    10801 atagtattct cagggtttca gccagcaaaa ttaaaagata ttatttaact agacaaggaa
    10861 caattgatat gagtctcaaa gatcttggcg atatttctta ctttcgcctc aacaatgaaa
    10921 ttaaccgtcc tgttgatggc agcattccac ttcataaaga caaggaagct ttggaggctt
    10981 tttttaccga aaatgttatt cctaacacca tgtcattttc ttctatcaac gaaaagattg
    11041 cctatcttgt agacaatgac tatattgaat cagcctttat ccaaaactat tctcctgaat
    11101 ttatcagcca tctagccaag agcattcaag cagagggctt tcgctttaaa tcatttatgg
    11161 cggcctataa attttatcag cagtatgccc taaaaaccaa tgatggcaat ttctacttag
    11221 agagcataga ggatcgggtc atgttcaatg ccctttattt tgctgatggt gatgaaacat
    11281 tagctaagga cttagccatt gagatgatta atcagcgtta ccaacctgct actccttctt
    11341 ttttaaatgc tggacggagc cgtcgtggtg agctggtttc ttgctttctc cttcaggtga
    11401 cagatgatat gaatgccatt ggccgctcta ttaattctgc cttgcaatta tcccgtattg
    11461 ggggtggtgt tggcattagc ctatccaacc ttcgtgaggc tggcgctcca atcaagggct
    11521 atgccggagc tgcttctggt gttgtgcctg taatgaagct atttgaggac agcttttctt
    11581 attccaacca gctagggcag cgtcaagggg ctggtgtggt gtatttaagc gtctttcacc
    11641 ctgatattat cgcttttttg tctaccaaaa aagaaaatgc agatgaaaag gtgcgggtca
    11701 agacattgtc acttggtatt actgtaccag ataagtttta tgagcttgct cgtcacaatg
    11761 ctgacatgta tctctttagc ccttatagtg ttgaaagaga atacggcctg ccatttaact
    11821 acattgatat tactagcatg tatgacgaat tggttgccaa tcctaatatc accaaaacaa
    11881 aaatcaaagc acgtgatttg gagacagaga tttccaagct ccagcaggaa tctggctatc
    11941 cctatgttat caacatcgac actgccaaca ggtcaaaccc tattgacggt aaaatcatca
    12001 tgagcaacct atgctcagaa attctacagg ttcaaacgcc tagtctcatt aatgatgcgc
    12061 aggagtttgt caaaatggga actgatattt cctgcaatct gggatcaact aatatcttaa
    12121 acatgatgac gtcacctgac tttggtcgtt ccatcagagc catgacacgt gccctgacct
    12181 ttgtcactga ctcctctaat atcgaagcag tcccaactgt taaaaatggt aacagtcaag
    12241 cacatacctt tggccttggg gctatggggc ttcattccta tttggctcag caccatatcg
    12301 aatatggcag cccagaatct atcgaattta ctgatattta ctttatgctg atgaattact
    12361 ggacgcttgt cgaatccaat cagatcgctc gcgagcgtca gacaaccttt gttggctttg
    12421 aaaaatcaac atatgctagc ggtgcttatt ttgaccagta catcacagga gaatgtgtgc
    12481 caaaatcaga gctggttaaa agccttttca aggatcactt tattccgcaa gcagcagact
    12541 ggaaggcgct gcgtcaagcg attatgacag atggccttta tcaccaaaac cgtctggcag
    12601 ttgctcctaa tggatcaatt tcctatatca acgactgctc tgcttctatt cacccgatta
    12661 ctcagcggat cgaagaacgt caggaaaaga aaatcggcaa gatttattac ccagccaacg
    12721 gcctatctac agacaccatt ccttactaca catctgccta tgatatggac atgagaaagg
    12781 tgattgatgt ctatgcagct gctacaaagc atgttgatca gggactgtcg ttaacactct
    12841 ttttgcgcag cgaattgcca aaggagctct acgaatggaa aacagaaagc aagcaaacca
    12901 ctcgtgacct atctattttg agacattacg cctttaataa agggataaaa tcaatctatt
    12961 atatccgcac ctttaccgat gatggcgagg aggtcggagc caatcagtgt gaaagctgtg
    13021 tcatctaacc aagtgaatgg cagtgaggtg gaccagtcct taatgtcaga gcctagctga
    13081 tgtgtcagtg cacctgtcct aatgatagac cagcactcaa ggctctcctc ctagcatacc
    13141 taaccctata ttacaatcta ccggagaaac tcatgaccac atactatgaa gcaatcaact
    13201 ggaatgaaat cgaagatgtc attgacaagt caacctggga aaagctgacg gagcaattct
    13261 ggcttgatac acgtattcca ctatcaaatg accttgatga ctggcgcaga ttatctgctg
    13321 ttgaaaagga tttagtaggt aaggtctttg gcgggctaac ccttcttgat acgatgcagt
    13381 ctgagtcagg agtcgaagcc attcgcaagg acgtgcgcac cccgcatgaa gaggcagttc
    13441 ttaacaatat ccaatttatg gagtctgtcc atgctaaatc ctactcatca atcttttcga
    13501 ccctaaacac caaaaaagaa attgaagaca tttttgagtg gaccaacaac aacgtatttc
    13561 ttcaaaataa ggctaagata atcaacgaca tttatgaaaa tggcagtgcc cttcaaaaaa
    13621 aggtagcctc gacttatctc gaaacctttc tattttattc tggctttttt acaccactct
    13681 attatctggg caacaataag ctggctaatg tcgctgaaat tattaagctc atcattcgtg
    13741 atgagtccgt tcatggcact tatatcggct acaagtttca gctgggcttt aatgagctat
    13801 cagagagtga gcaagaaagc cttcgtgact ggatgtatga cctgctgtat cagctatatg
    13861 aaaatgaaga gcaatacacc aagaccctct atgatgaggt tggctggacc gaggaagtga
    13921 tgaccttcct acgctacaac gctaacaagg ctttgatgaa ccttggtcag gaccctcttt
    13981 ttccagacac tgccaatgat gtcaacccaa tcgttatgaa tggtatttca accggcacgt
    14041 caaaccacga tttcttctct caagttggta atggctacct tcttggtact gttgaagcta
    14101 tgactgatga cgattacaat tatgggctat aagtccagct tctcatgaag attggattta
    14161 tctatatttt ggagcctgag tagtctcagg ctctttttat ctgctataat aaaagatatg
    14221 attactcgat tgattacttt cttaacatgg acgggccaac tggtggtagc tggtgtgatt
    14281 gctggtgtgg tggcttacgt gctcactcaa gccattcatt tcatacaggc tattagcttt
    14341 ggataccaat ctgggtcttt tagcaccatg attgcaacgg tagctccaga aaggcgtttt
    14401 ttatctctat tgttggctgg agctattgct ggtctcggct ggcagctact tgctaaaaaa
    14461 gccaagccta ttcagcctat ccaacaaaca ctcagtcagc aaaaggattt cagcccttgg
    14521 acacaatttt gtcatggctg gctgcaatta ataaccgtct ccatgggagc acctgtcggt
    14581 cgtgaaggtg cttcacgtga ggttgctgtg gcactgactg ccgcttgcaa taaagctata
    14641 aacgcatcag cagcagagca aggattgctt ttagcctgtg cttcaggagc tgcccttgga
    14701 gctgtttacc aggcaccatt agctacgatt gtctttatca tggaggctat tgtcaaaaaa
    14761 tgctcagtta aacacattta cgcggcagct ataactgcct ttactgctgt tcaaagtgtg
    14821 cttgttctaa gcggacatca ggacatacag tatctcattc tcccacaagc ctggcaactg
    14881 acaacagtcc tttgggctat cattgccagt cccatcttag catttctggc cttttgctac
    14941 cagcagctgc tccaaaacgc accaaaggca aagcctaaga gccgatggtt tatccctcgt
    15001 gtcttagggg cttttggctt tagtgcttgt ttaagccttt atttcccaga gattttaggc
    15061 aatggcaagg ccggtctcct cctgctgcta caccatgatg tcagcctatc ttataccgcc
    15121 tcgctcttac taagtaaagc agctgctgtc tatgcagtat ttgcctctgg agctaaagga
    15181 ggcaaaattg ctccttctat gatgcttgga ggagctagtg gcttgctact ggcaagcctt
    15241 agcaatcagc taggttatct ctctgtacca cttcccttgg ccattgtcat tggagcgacc
    15301 ctctttttgg gaatcattaa tcagatacct cttactgctc ctctttttct cattgaaatt
    15361 accggacaac ctctcattag ccttgtgccg cttgcaattg taggtttgac aagctatctc
    15421 agccaacagc tctttcaaaa aagcctcttt ttcaacaaac acaaaaagct ttgatcgcca
    15481 gtaatggctt atcaaagctt ttttgctgta taacaattct tgagtaggta aaaccttacg
    15541 ccttacctat aaaaatcatg tgctgattta aaggatttca ccagaatata gaggtgaata
    15601 ctagcagtaa tgattagtcc ggtcagctca accctttgaa aaatcataga taaaagcaat
    15661 aatattacgt aaatgcctgg taatataaag ccactaaggc ccatgacaac ctcaaaagac
    15721 atttgataat tagcctgcaa ttctgcctcg tcctgttgta agatattctg ctttaattcc
    15781 tttaaggtag gagcaagcgt catcttgacc ccgcgaatcc gagtataaac cttcaaaata
    15841 taagcatgga gaacactaat aaccacaagc atcagagcct cgtaaatagg aaaagtcaaa
    15901 ccaagatagc tagcattatt agcaataggc accctatatc ccaaagaaaa aacgactata
    15961 ttcaagacca tagccatagc gctaaatcct aaagcatagg catgcttaag attaatgtaa
    16021 cggtacagct cctctgtttc atcatcgctt agcttgacat atctagcata ttctttgaca
    16081 acttgataaa tatcataaat gctcagcagc ataagcacga taacaagggg tctcattccc
    16141 cactttattc cagttatggt gtcttcttct gatatcggaa agccattttc taatatgtta
    16201 aacctagcta aaccaaaacc aacaaggcca cctaacacta agccaatccc tgatccaagc
    16261 agtaatgact taagtattct caccaacgta ctgtcctttt ccgtcataaa agctttcatc
    16321 tctcgccctc cactaagcta aatacttgtt caattggttc attaaatact ttagcaattt
    16381 tcattgcaat aataatagat ggtgtgtatt catttcgctc aatgaggcta atggtctgcc
    16441 tggaaacacc tgctaatgct gccatctgcg tctgattaat gccatctcta gctcgtagct
    16501 ccttgagccg atttctcaac ctataagcca tgcttcactc ctaataaatg ctgtctcctg
    16561 attgaacaga aagcaccagt catttccggc aacaatccat tgacacaatg gtataagctt
    16621 aaaatagctt tgttattgtt atcctactga ttactttttt ctttcatgag tccaactcca
    16681 gtgtaacaga tcatttactt tttgacaata atatttgtca aaaatagaaa cattgtcata
    16741 tgataaaaga atgcaatcac catctatgag ctttcttgta acaataaaaa accaagctcc
    16801 atcgaactta gcttaacctg ttgtcatcac tgttgtaaca gaaaataagc accttaaaaa
    16861 cactagatga ctaacaataa aacaatagct gctagttcca ttcaactcac tgataacaaa
    16921 tatcccgcat ggaaaaatca gtttattgtt tcgcacgatc attactatct cacctgtgat
    16981 atagctacaa tctactgttc gtctcaattt gttta
//
LOCUS       DARYXW010000046        15750 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.046, whole genome shotgun sequence.
ACCESSION   DARYXW010000046 DARYXW010000000
VERSION     DARYXW010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15750
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.046"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            13..741
                     /locus_tag="TV191_001195"
     CDS             13..741
                     /locus_tag="TV191_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1507713.1"
                     /translation="MIKEQPLYLQIVDVLEVKIRNTMSANDKLLSERELSDLFGVSRI
                     TIRLALKELELRGLIYKQQGKGTYVSGIKEPATDLSSAYSFTEEMKKQGRKPQTVILS
                     FEKIKTTAYLSGMLDLDVDTDVFELERLRIADGKPLMFERTYIPERGFEAITIDLLEK
                     KPLYDVFAEDFQEAIRLADEEFYASIALDYEAKLLGIKKGDPVLHIMRKTYNEKNRLI
                     EFTFSIARADQFRYRIQHHPNKKI"
     gene            753..1928
                     /locus_tag="TV191_001196"
     CDS             753..1928
                     /locus_tag="TV191_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEL1507714.1"
                     /translation="MFTKTQAELELLGAAITTREIKQQPELWSEVFESFLKQKKDLLA
                     FFDRIIESANRNKVKIIFTGAGTSEYIGNTICHYLEMTGDRENYLYYSIASTDLVAAP
                     SQYLFEEDTVVLVSFARSGNSPESVAAVSLVNQLVSNPYHLVITCAKEGALAQNAKKD
                     KRSYLFLLPEASNDAGFAMTGSFSCMMLAALLIFDQAHSLEEKKCYLDQIVGMVAAII
                     QQEADLQKLVSLEFQRLVYLGSGALAGLTQEAQLKILELTAGKIATVYDSSMGFRHGP
                     KSFIDDQTLVIGFVSNDPYTRRYDLDVLEEIREDAIAVDTVALQQQGGEGFSGHCFGL
                     DSSMLLPDAYLAFPLVFIAQTLALLSSIKVNNLPDTPSATGTVNRVVQGVKIYHYFK"
     gene            1938..2933
                     /gene="lacD"
                     /locus_tag="TV191_001197"
     CDS             1938..2933
                     /gene="lacD"
                     /locus_tag="TV191_001197"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEL1507715.1"
                     /translation="MYHLSKAKYRLLEKVSRKGIISALAFDQRGVLKRMMAAHQDTEP
                     TPWQIEALKALVSEELTPYASSILLDPEYGLPATKVRDEKSGLLLAYEQTGYDTTTTS
                     RLPDCLVDWSVKRLKEAGADAVKFLLYYDVDGDERINQQKQAYIERIGSECQAEEIPF
                     FLELLTYDEAITDNQSVAFAKLKAHKVNEAMKVFSTERFGVDVLKVEVPVNMAYVEGF
                     AEGEVVYSKEEAMQAFRDQEAASHLPYIYLSAGVSASLFQETLVFAAEAGARFNGVLC
                     GRATWSGAVAVYMSEGEEAARQWLRTEGFENIDRLNQVLEKTASPWTTKLTLDEA"
     gene            complement(2975..3694)
                     /locus_tag="TV191_001198"
     CDS             complement(2975..3694)
                     /locus_tag="TV191_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1507716.1"
                     /translation="MTIKYPKYRLIKEELQNQILNGHYHTGDKFYTEAELIKRFHVSS
                     ITIIRALKELEKEGFIRRRQGLGTFITRTRKEQLVQFSYLGTFKDQKEEVTVLSVVKG
                     NDPYYLNLLKLHKTEFYYTISRTRTINQQPYLYQLSYIPHDYLLCPERDLADYQSLYK
                     RFFLDFHIQMRSQSFTQQTQLTDHMPKDVATFLNMIDNTPCVLQTKLTRSTDNGRILE
                     YTESYKHWQFFKYALSSSDYQ"
     gene            3834..5597
                     /locus_tag="TV191_001199"
     CDS             3834..5597
                     /locus_tag="TV191_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEL1507717.1"
                     /translation="MKQFCIKEQFYLDGKPFKILSGAIHYFRIAPDSWSRVLYQLKAL
                     GFNTVETYIPWNMHEPRKGQFTFEGIADVEAFLDLAQECGLYAIVRPSPYICAEWEFG
                     GLPAWLLTENCRLRSSDEVFLKHVSDYYDVLLPKLVKRQLDNGGNILMFQLENEYGSY
                     GEEKAYLRKLKELMLAKGISAPLFTSDGPWPATLASGSLIDDDVFVTGNFGSNASKQF
                     ASMQDFFQAHQKQWPLMCMEFWLGWFNRWNEPIIRRDSKEAVDAIMEAIELGSINLYM
                     FCGGTNFGFMNGSSARLQKDLPQITSYDYDALLDEAGNPTKKYTLLQERLKECYPQLS
                     FAEPMISSTMALESIKLSARVSLFKTIKNVSAIKKSFYPCNMEELDQPTGYLLYRTHL
                     ARHSKEERLRVIDARDRIQLFLDEKHVKTQYQEEIGQDILIHQEGETTQLDILVENMG
                     RVSYGYKLTAPSQQKGLGRGLMADLHFVGDWEHFPLDFQELDWIDFSAGWTDEVPGFY
                     AYDFDCQQPADTYLDLSQFGKGIALVNGVNLGRFWKVGPTLSLYIPKGLLKQGQNRLL
                     IFETEGQFSESIRLTKEPIYK"
     gene            5615..6100
                     /locus_tag="TV191_001200"
     CDS             5615..6100
                     /locus_tag="TV191_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1507718.1"
                     /translation="MTIVAARIDGRLIHGQVANLWTTKLNISRIMVVDNEVISNDLEK
                     TALKLATPSGVKLSILSVEKAANNILEGRYDSQRLLIVARKPDSFLELIQKGVAISEL
                     NVGNMSQTPETRPVTRSINVVDEDIEAFKAISAKGCHLIAQMVPNDAPADFMPLLDKV
                     D"
     gene            6146..7027
                     /locus_tag="TV191_001201"
     CDS             6146..7027
                     /locus_tag="TV191_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEL1507719.1"
                     /translation="MIQWWQILLLTLYSAYQILDELTIVSSAGSPVFAGFISGIIMGD
                     VQTGLWIGGSLQLMVLGVGTFGGASRIDATSGAVIATAFSVAQGIEPELAISTIAVPV
                     AALLVYTDILGRFSTTFFAHRIDRHVENFNYRGIERDYLMGAVPWALSRALPVFLAVS
                     LGGGAVDTVVKFIDHYEWLANGLTLAGKMLPGLGFAILLHYLPVKRNLHYLALGFGLT
                     AMLTTIYTNLQVAGGALAGVAKDFNAAPFKGLPMIGIAIIGLSLATLHYKNGQQAPVA
                     EQKPGVSESGEIEDDEI"
     gene            7014..7832
                     /locus_tag="TV191_001202"
     CDS             7014..7832
                     /locus_tag="TV191_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HEL1507720.1"
                     /translation="MTKSNYKLTKQDFNQINKRSLFTFQWGWNYERMQGSSYLYMILP
                     QLRKIYGDGTPELKEMMKTHTQFFNTSNFFHTIITGIDLALEENEGLASKDAVNGIKT
                     GLMGPFAPIGDSVFGSLVPAIMGSIAAGLAKEGVWSGITGVLMWVCTQMIINVFRWKQ
                     LEIAYKEGTKLVTTMRDKLTAVVDAASVMGVFMVGALIATMINFQFTAAPKIGEKVIN
                     IQDLIDTIFPRLVPALFTGGIFWLLGRKGMSPTKAIVVIILFALVMSYFNILGV"
     gene            7836..8240
                     /locus_tag="TV191_001203"
     CDS             7836..8240
                     /locus_tag="TV191_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HEL1507721.1"
                     /translation="MAQTLILISHGAFCRELKQSTEMIMGPQDNILTAELQPNEGADD
                     FKEKLLRLIAGLDDVLVFADLMGGTPCNVASRLLMEGHQFELYAGMNMPMVIGFINAC
                     LIGEAFDFKAFACDNIHHVNTIISALADDDDD"
     gene            complement(8344..8604)
                     /locus_tag="TV191_001204"
     CDS             complement(8344..8604)
                     /locus_tag="TV191_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEL1507722.1"
                     /translation="MRKDIHPDYRPVVFLDTTTGYKFLSGSTKTSKETIEFEGETYPL
                     VRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAK"
     gene            complement(8729..9661)
                     /locus_tag="TV191_001205"
     CDS             complement(8729..9661)
                     /locus_tag="TV191_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEL1507723.1"
                     /translation="MTTFQTILEHIKHYQTIIIHRHQNPDPDALGSQAGLKEIIRHNF
                     PDKKVLITGFDEPSLAWISLMDQVSDDDYKEALVIVTDTANRPRIDDERYTMGACLIK
                     IDHHPNDDVYGDLSYVDTKTSSASEIIAEFAFSQGLALTDEAARLLYTGIVGDTGRFL
                     YASTSSKTLAIASQLRNYAFDFAAISRQMDSFPLKIAKLQGYVFEQLDIDDSGAARLL
                     LSQEVLNSFGISLAESSAIVSAPGKIDVVQAWVIFVELPDGQYRVRMRSKEKVINGIA
                     KRHQGGGHPLASGATSSGLEENEQIYQELIDLLT"
     gene            complement(9671..10099)
                     /locus_tag="TV191_001206"
     CDS             complement(9671..10099)
                     /locus_tag="TV191_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1507724.1"
                     /translation="MWVVKAFDQLTKDELFAIYKERVAVFVVEQQCPYPDIDDLDQKA
                     IHLFKQVDSELRAYCRLIPTDNSIKLGRVLVAQNARRTGLGRDLVHQALAYCQQHFPK
                     LPVYAQAQAYLEPFYSSFGFKAVSEIYLEDNIPHIDMIKN"
     gene            10357..11382
                     /locus_tag="TV191_001207"
     CDS             10357..11382
                     /locus_tag="TV191_001207"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HEL1507725.1"
                     /translation="METKDLKKLAKAELHCHLDGSLSLDTIRQLAALAQVDVPQDDSE
                     LKQLVTAPETCESLMDYLKTFDVIRPLLQTPQALTLAAYDVVKQAALENVIYIEIRFA
                     PELSMDQGLTATQVVEAVLKGLEQGQKEFGIVAKAIVCGMRQSSLDISREIFANVLEW
                     ANKGLVGFDFAGNELDFPPAVLADLIKETQAYGLPFTLHAGECGCPNYIVDAIDLGIK
                     RLGHVTAIHNQKDLLAKFIANDVTAELCFTSNLQTKAARTVEDFPYMQLRQAGAKLSI
                     NTDNRTVSDTNLTKEYELFVKHFETSVTDFLEHNRDAIKASFASPAEKEALLDRLEKA
                     YQSYIKK"
     gene            11443..11889
                     /locus_tag="TV191_001208"
     CDS             11443..11889
                     /locus_tag="TV191_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEL1507726.1"
                     /translation="MALAKIVYASMTGNTEEIADIVANKLQELGHDVEVDECTTVDAS
                     ELEAADMAIVATYTYGDGDLPDEIVDFYEDLQDLDLSGKIYGVVGSGDTFYDYFCKSV
                     DDFDEQLAATGATKGADSVKVDLAAEEEDIARLESFAEQMSQALEA"
     gene            12218..12511
                     /locus_tag="TV191_001209"
     CDS             12218..12511
                     /locus_tag="TV191_001209"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEL1507727.1"
                     /translation="MGLETIRQDINAVDRQLIALLEKRMVLADQVAAYKQVHDVPVLD
                     QEREAEVLRSVSQQIRHKAFEPAILELFKTIMAVSRRYQAEQIAVGSNDDEAY"
     gene            12492..13723
                     /locus_tag="TV191_001210"
                     /pseudo
     CDS             12492..13723
                     /locus_tag="TV191_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622696.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
     gene            13869..14216
                     /gene="rplS"
                     /locus_tag="TV191_001211"
     CDS             13869..14216
                     /gene="rplS"
                     /locus_tag="TV191_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEL1507728.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGSRERIQIFE
                     GVVISRKSQGISEMYTVRKISSGIGVERTFPIHTPRVEKIEVVRHGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            14731..14802
                     /locus_tag="TV191_001212"
     tRNA            14731..14802
                     /locus_tag="TV191_001212"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:14764..14766,aa:Arg,seq:cct)
     gene            complement(14926..15729)
                     /locus_tag="TV191_001213"
     CDS             complement(14926..15729)
                     /locus_tag="TV191_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL1507729.1"
                     /translation="MSKSRRRNWKSLTIVLLTILTIFTANSVQSARKLRTFPDTTEIS
                     LGTKATEIPGILPFTGKYQIALGDLDHLQRATYAHIQLKDQDEPTLKRKALRFNPPGW
                     HNYQVINSRGKKTWLMDRGHLVGYQFSGLNDEPKNLVTMTKYLNTGFSDKNPLGMLYY
                     ENRLDNWLAIHPNFWLDYKVTPIYQNDELVPRQVVLQYVGIDQNGELLQIKLGGNKES
                     VDHYGITSVVLDNVSPLAALDYRTGMLLDENQHTEEGNNLATEELDEAA"
BASE COUNT         4365 a         2969 c         3695 g         4721 t
ORIGIN      
        1 agaggtgtta gtatgataaa ggaacagcca ctctacttac aaattgttga tgtattagag
       61 gtcaaaatta gaaataccat gtcagctaat gataaattgt tatcagaacg agagctaagt
      121 gacttatttg gtgttagtcg gataaccatt agattggcac ttaaggagct agagctgcgt
      181 gggcttattt acaaacagca gggcaagggg acctatgtat caggcataaa ggagcctgct
      241 acagacctgt cctcagccta tagctttacc gaagagatga aaaagcaagg tcgtaagcct
      301 caaacagtca ttctttcatt tgaaaaaatc aagaccacag cttacttgtc tggtatgtta
      361 gatttagatg ttgatactga tgtttttgag ctagagcgtc taaggattgc agatggaaag
      421 ccattaatgt ttgagcgcac ttatatacct gaaaggggat ttgaggcgat aacgattgat
      481 ttattggaaa aaaagccctt atatgatgtg tttgctgagg attttcagga agctatccga
      541 ttggctgatg aggagtttta cgctagtatc gctctagatt atgaagcaaa gctattaggg
      601 atcaaaaagg gggatcctgt gctgcatatt atgcgtaaga cctataatga gaaaaatagg
      661 ctaatcgaat ttacctttag tattgctaga gcagaccagt ttaggtaccg tatccagcac
      721 caccctaaca agaagatata ggaggtaagg aaatgtttac aaaaacacaa gcagaactag
      781 agctacttgg cgcagctatc accactagag aaatcaagca gcagccagag ctatggtcag
      841 aggtctttga gtcttttctg aagcaaaaaa aagacctctt agcctttttt gacaggatta
      901 ttgaaagcgc taacagaaac aaggtaaaaa ttatttttac aggagctgga acttctgaat
      961 acattggcaa taccatttgt cattatttgg agatgactgg tgacagggaa aattatttat
     1021 attacagcat tgcttccaca gaccttgttg cagctccaag ccagtatctc tttgaagagg
     1081 atacagtcgt gcttgtttcc tttgcaagaa gtggcaatag tcctgaaagt gtcgctgctg
     1141 ttagtcttgt taatcagctg gtgtcaaatc cttatcattt ggtgataacc tgtgccaaag
     1201 agggggcctt agctcaaaat gctaagaagg acaaaaggag ctatttattc ttgctgcctg
     1261 aggcctcaaa tgacgctggc tttgctatga cgggaagctt tagctgcatg atgctagcgg
     1321 ccttgttgat ttttgatcaa gcgcattccc ttgaggagaa aaaatgctat ttagatcaga
     1381 ttgtaggtat ggtggcagct attattcagc aggaggctga tttacaaaag ctggttagct
     1441 tagagtttca acgcttggtt tacctgggat caggagcctt agcggggctt acgcaagagg
     1501 ctcaattgaa gattttagaa ttaacagctg gcaaaattgc aacagtctat gactcctcaa
     1561 tgggctttag gcatggtcca aagtcattta ttgatgatca gacattggtt attggttttg
     1621 ttagcaatga tccttatacg agaaggtatg accttgatgt tttagaagag ataagagagg
     1681 atgctattgc tgttgatacg gttgcattac agcagcaagg aggtgagggc tttagtgggc
     1741 attgctttgg cttagactcg tcaatgctat tgccagatgc ttatttggcc tttccgcttg
     1801 tttttatcgc ccaaacgctt gctttgctgt cgtctattaa ggttaataat ttaccagata
     1861 ctccttcggc cacaggaacg gttaacaggg ttgtccaagg tgttaagatt tatcactatt
     1921 ttaagtagga gaacaagatg taccatttat caaaagctaa gtatcgtctt cttgaaaagg
     1981 tcagtcgtaa gggcatcatt tcggccttgg cctttgatca acgcggggtt ttaaagcgca
     2041 tgatggcagc ccaccaagac acagagccaa ctccttggca aatcgaagcc ctaaaggctc
     2101 tggtatcaga ggagctaacc ccctatgcct cctctatcct gctagaccct gaatatggcc
     2161 tgccagccac caaggtgcgt gatgagaagt ctggcttatt attagcctat gaacaaaccg
     2221 gctatgacac aaccaccact agccgcctgc cagattgtct ggtggactgg tcagtcaagc
     2281 gcctcaagga ggccggagct gacgcagtga agttcttgct gtactatgat gttgatggtg
     2341 atgagcgtat taaccaacaa aagcaggcct atatcgagcg tatcggctca gaatgtcagg
     2401 cagaggagat accatttttc cttgagctat tgacctatga tgaggcgata acagacaatc
     2461 agagtgtagc ttttgccaag ctaaaggcac acaaggttaa tgaggccatg aaggtctttt
     2521 caactgagcg ctttggggtt gatgtcctaa aggtagaggt tcctgtcaat atggcctatg
     2581 ttgagggctt tgcagagggt gaggttgttt acagcaaaga ggaggctatg caggcctttc
     2641 gtgaccaaga ggcagctagt cacttgccct atatttattt gagtgcgggt gtatcagcta
     2701 gtctgtttca agagaccttg gtttttgcgg cagaggcagg agctaggttc aatggtgtgc
     2761 tgtgtggtag ggccacttgg tcaggagcag tagcggtgta catgtcagag ggcgaggagg
     2821 cagcgcgtca atggcttcgc acagagggtt ttgaaaatat tgatcgtctc aatcaggtgc
     2881 ttgagaaaac agccagccct tggacaacaa agcttactct tgatgaagcc tagtaaaggc
     2941 atgataaaag caatactagg acattgcttc tgtattattg gtaatcactg gaggacaagg
     3001 cgtacttgaa aaattgccaa tgcttgtagg actcggtgta ctctagaata cggccattat
     3061 ctgtcgaccg agtgagcttg gtttgaagga cacaaggagt gttgtctatc atgtttaaaa
     3121 atgtagcgac atctttaggc atgtgatccg tcagctgtgt ttgctgggtg aagctttgtg
     3181 atcgcatttg aatgtgaaaa tccaaaaaga agcgcttata aagcgactgg taatcagcta
     3241 aatcacgctc agggcacagc aggtaatcat gaggaatata agatagctgg tataaatagg
     3301 gctgctgatt aatcgttcgt gtacgggaga tggtgtagta aaattccgtt ttatgaagtt
     3361 tcaagagatt tagatagtag ggatcatttc ccttaactac actaaggaca gtcacctcct
     3421 ctttttgatc cttaaaggta cctagatagg aaaattggac tagctgttct tttctggtac
     3481 gggtaatgaa ggttccaagt ccctgccttc ttctgataaa gccttctttt tctagttctt
     3541 taagggctcg aatgatggtt atggagctaa catgaaagcg tttaatcagc tcggcttcgg
     3601 tataaaattt gtccccggta tggtagtggc cattcagaat ttggttttgc aattcttctt
     3661 tgattagtcg gtactttggg tatttgatgg tcatagttac tcactcaata attgtttagt
     3721 acgattatag caaaaatagt aagctgatgt catatcttac cagttattgc tcagatagct
     3781 tgtcaatcag tcattgatca aaggctgatg gttaatgaat aaaaggagat aatatgaagc
     3841 aattttgcat aaaggagcag ttttaccttg atggcaagcc gtttaagata ttatcaggtg
     3901 ccattcatta ctttagaata gctcctgata gctggtctag ggtgctttat cagctgaagg
     3961 ccttaggctt taatacagta gaaacctata ttccttggaa tatgcatgag ccaaggaagg
     4021 gacagtttac ctttgagggg attgcagatg ttgaggcatt tttggatttg gcacaggaat
     4081 gtggcctata tgctattgtc agaccctctc cttatatctg tgctgaatgg gagtttggtg
     4141 gtttaccggc ttggctatta actgaaaatt gtaggctcag atcaagcgat gaggtctttc
     4201 ttaagcatgt atcagattat tatgatgtgt tactaccaaa gctggtgaag cgtcagttag
     4261 ataatggcgg caatattctg atgtttcagc ttgaaaatga gtatggttct tatggtgaag
     4321 aaaaggctta tttaagaaaa ttaaaagagc ttatgcttgc taaaggcatt agtgcccctc
     4381 tctttacctc agatgggcct tggccagcca cgctagcatc agggagtctg attgacgatg
     4441 atgtttttgt gacaggcaac tttgggtcaa acgcttcaaa gcaatttgcc agtatgcagg
     4501 attttttcca agcacatcaa aagcaatggc ctctgatgtg tatggaattc tggttgggct
     4561 ggtttaatcg ctggaatgag ccaatcattc gaagggactc caaggaagct gttgatgcaa
     4621 tcatggaagc tatagagcta ggcagcatta acctttatat gttttgtggt ggcactaatt
     4681 ttggctttat gaatggctcg tcagctcgtc tgcaaaagga tttaccacag ataacctcct
     4741 atgattacga cgcattacta gatgaggcag ggaacccgac aaagaaatat accctgctgc
     4801 aagaacgtct caaggagtgt taccctcaat tatcctttgc agagccaatg atcagttcta
     4861 cgatggcctt agagtctatc aagttgtcgg caagggttag tctttttaag acaatcaaaa
     4921 atgtaagcgc tatcaagaaa agtttttatc cttgtaatat ggaggagcta gatcaaccaa
     4981 cgggctacct actgtataga acgcacctcg ctagacatag caaggaggag cggctcaggg
     5041 tcattgatgc tagagaccgc attcagctct ttttagatga aaagcacgtg aaaacccagt
     5101 atcaggagga aatcggtcag gatatactga tacatcaaga gggtgagacc acacagcttg
     5161 atattttagt cgaaaatatg ggacgtgtca gctatgggta caagctgaca gcaccaagcc
     5221 aacaaaaagg attaggcaga ggcttaatgg ctgacttgca ttttgtaggt gattgggagc
     5281 attttccact agattttcaa gagctggatt ggattgattt ttctgcaggt tggaccgatg
     5341 aggtgccagg attttacgcc tatgattttg attgtcagca gccggcagat acctaccttg
     5401 atttgagtca attcggaaaa ggaattgccc ttgtaaatgg tgttaaccta ggacgttttt
     5461 ggaaggtcgg tccaacatta tcgctttata ttcctaaggg actattaaaa caaggtcaaa
     5521 atagactgct gatatttgaa acagaagggc agtttagtga gtcaattcgt ttaactaagg
     5581 aaccaattta taaatagata aaaggagaaa acttatgaca attgttgcag cacgtattga
     5641 cggccggtta attcatggtc aggtagctaa tctatggacg acaaagctaa acattagccg
     5701 tatcatggtg gtcgataatg aggtgattag caatgacctt gaaaaaacag cactgaagct
     5761 agccacacct agcggtgtta aattatctat cttatctgtt gaaaaagcag ccaacaatat
     5821 tttggaaggg cgctatgatt ctcaacgctt gttgatagta gccagaaagc cggatagctt
     5881 tttggagctg attcaaaaag gggttgctat ttcagagtta aatgtcggca atatgtcaca
     5941 gacaccggag actcgtccag taacgcgttc tattaacgtt gtagacgagg atatagaggc
     6001 attcaaggct atttcagcca aagggtgtca tctcattgcc caaatggtgc ctaatgatgc
     6061 cccagcagac tttatgccgc tgttggataa ggttgattaa gatgtgtcaa atcaaaaacg
     6121 aatctgtttc aggaggtaaa agcttatgat tcaatggtgg caaatcctat tattaacact
     6181 ctactcagct tatcaaatat tagatgagct aacaattgtc tcttctgcag gctcacctgt
     6241 atttgcagga tttatttcag gtatcatcat gggagatgtg caaaccggtc tttggattgg
     6301 tggtagcctt caattgatgg tgcttggtgt tgggaccttt ggaggagctt cgcgtatcga
     6361 tgcaacctct ggtgcggtta ttgcgacagc cttctcggtt gctcaaggca tagagccaga
     6421 attagcgatt tcaaccattg cagttccggt agcggccttg ctggtttata ctgatattct
     6481 aggacgcttt tcaacgacct tctttgctca ccgtattgac cgccatgttg aaaactttaa
     6541 ctaccgaggc atcgagcgtg attaccttat gggagctgta ccttgggccc tatcacgtgc
     6601 tctgccggta tttttagcgg tctctttagg tggtggtgcg gttgatacag ttgttaagtt
     6661 cattgaccat tatgaatggc tagcaaatgg tctaactctt gcaggaaaaa tgcttccagg
     6721 cttgggcttt gcgatcttgc ttcactacct accagttaaa cgtaatctcc attatctggc
     6781 tttaggtttt ggcttgacag caatgctaac aaccatttac accaaccttc aggtagctgg
     6841 aggcgccctt gcaggagtag ccaaggattt caatgccgca ccattcaagg ggctgccaat
     6901 gattggtatt gctattattg ggctttcctt ggcaaccctc cattataaaa atggtcaaca
     6961 agcacctgta gctgaacaaa aacctggggt atcagaaagt ggggaaattg aagatgacga
     7021 aatctaatta taaattaacc aaacaggatt ttaatcaaat caataagcgc agcctgttca
     7081 cattccaatg gggctggaac tacgagcgta tgcagggctc tagctatctt tacatgattt
     7141 taccacagct tcgtaagatt tatggcgatg gaactccaga gctaaaagaa atgatgaaga
     7201 cgcacacgca gttttttaac acatcaaatt tctttcatac gattatcaca ggaattgact
     7261 tggcgttgga ggaaaatgaa ggacttgcct caaaagatgc tgttaatggg attaaaacag
     7321 gcttaatggg gccatttgct ccaattggtg attcggtctt tggctcctta gtaccagcta
     7381 ttatgggctc tatagccgca ggtcttgcta aagaaggggt ttggtcaggg attactggtg
     7441 tattgatgtg ggtatgtact cagatgatca tcaatgtgtt tcgttggaag cagcttgaaa
     7501 ttgcttataa agaaggtaca aagctcgtca ccaccatgcg tgataagcta actgctgtag
     7561 tagatgcagc ctcagtcatg ggagtattca tggtaggggc cttaattgca acaatgatta
     7621 attttcagtt taccgcagca cccaaaattg gagagaaagt tatcaatatt caagatttaa
     7681 ttgataccat ttttccacgt ctagttccag ccttatttac cggaggtatc ttctggctgc
     7741 tagggcgtaa gggcatgtca ccaactaagg caattgttgt gattatttta tttgccttag
     7801 tgatgtctta tttcaatatt ttaggagtat agctgatggc gcaaacctta attctcatta
     7861 gtcatggagc tttttgtcga gagctaaaac agagtacaga aatgattatg gggccacagg
     7921 acaatatttt aacagcagag ctgcaaccaa acgaaggtgc cgatgacttt aaagaaaagc
     7981 ttttaaggct aattgcaggt ttagatgacg tccttgtgtt tgcagatttg atgggtggaa
     8041 caccctgtaa cgttgccagt cgtttgttaa tggaaggaca tcagtttgag ctgtacgcag
     8101 gcatgaatat gccaatggtc attggtttca ttaatgcctg tttgatcggt gaagcgtttg
     8161 atttcaaagc ctttgcctgt gacaatattc accatgtcaa taccattatt tcagctctag
     8221 cagatgatga tgacgactaa ccaagctcgc ttatttgtca cgcaccttac ggagcgaaac
     8281 ggaccaagag ccgcataatc aaaaaagaca ctgccaaatc ttggcagtgt ctttgctgta
     8341 agcttatttt gctgcgtttg cgtctttgag accgtatttc ttgttgaaac gatccacacg
     8401 tccatcggct tgtgtaaact tttgacgacc tgtgtagaat gggtgtgagt ctgatgaaat
     8461 ttctacacga acaagagggt aagtttcccc ttcaaactca atggtttctt tagaggtctt
     8521 agttgaaccg ctaaggaatt tgtagcctgt agttgtatca aggaaaacaa ctggacgata
     8581 atctggatga atgtcttttc tcatcttaaa aaagttcctt tctgccatga tactgtccgt
     8641 atcatagtta ttaactactc tagtttaaca aaagttagta agcttgacaa gctttttcta
     8701 tcactattca tcaataagat gataagtctt atgttaagag atcaatcagc tcttggtaga
     8761 tttgctcatt ttcctctaag cctgatgacg tggcaccgct agcaagaggg tgcccgcctc
     8821 cttgatgacg cttagcaata ccattgatga ccttttcttt actgcgcatg cgtactcggt
     8881 actggccatc tggcagctca acaaagataa cccaagcctg caccacgtct atttttccag
     8941 gagcagagac aatcgctgag ctttctgcca agctaatacc aaaggaattt aggacctcct
     9001 ggctaagcag taggcgggct gcaccactgt catctatatc aagctgctca aaaacatagc
     9061 cttgtagctt ggcaatttta agtggaaagg aatccatctg cctcgaaata gcagcaaagt
     9121 caaaggcata atttcttaat tggcttgcaa tggccagtgt tttactgctt gttgaggcat
     9181 agagaaagcg tcctgtatct cccacaatgc cagtatataa tagtctagct gcctcatcag
     9241 ttaaagccaa gccttggcta aaggcaaatt cagcaataat ctcactagca cttgaggtct
     9301 tggtgtcaac gtaggagaga tcaccataga catcatcgtt agggtgatga tcaattttaa
     9361 tgaggcaagc gcccattgtg tagcgctcat catcaatgcg ggggcgattg gcagtgtctg
     9421 taacaatcac taaagcttcc ttataatcat cgtcggacac ctgatccatg agactaatcc
     9481 aagccagact aggctcatca aagcctgtta tcaggacctt tttgtcaggg aaattatgcc
     9541 tgataatctc tttaagtcct gcttggctcc ctagagcatc tggatcgggg ttttggtgcc
     9601 gatgaatgat gatggtttga tagtgcttaa tgtgttctaa aatagtttga aacgttgtca
     9661 taggtatcct ttagtttttg atcatatcaa tgtgaggaat attgtcttcc agataaatct
     9721 cagagactgc tttaaaccca aatgagctgt aaaaaggctc aagataagcc tgcgcttgag
     9781 cgtagacggg aagctttgga aagtgctgtt gacaataggc taaggcttga tgaactaagt
     9841 cacgtcctag tcctgttcgc cttgcatttt gtgctaccag tactcgtccc agctttatgc
     9901 tattgtcagt tgggattaag cgacagtagg ccctaagctc tgaatcaacc tgcttgaaaa
     9961 gatggatagc tttttgatcc aaatcgtcaa tatcaggata gggacattgc tgctcaacca
    10021 caaaaacagc cacacgctct ttatagatgg caaacaattc atcttttgtt aactgatcaa
    10081 atgctttaac aacccacatt agctagcctc caaaatcact ggtacaattt cctttatgat
    10141 aacataatag catatatcag ccataatgga acgaaaaaaa cctgactctt aatggacgat
    10201 gtcgtgatga taattacatc ttgtctcaaa agctggtaat catcacaggc acagaaaaat
    10261 gtgccccttc tgttgctttt tgagaaaaag ttcacttgct ttttggtagt tttttggtat
    10321 catactaaaa aatagactta attaaggaga tacagcttgg aaacaaaaga tttaaagaag
    10381 cttgctaaag ctgagctgca ctgccattta gacggttctt tgtcattaga cactattcgt
    10441 cagttggcgg ctttggcgca ggtagatgtt cctcaagatg attctgagtt aaagcagctg
    10501 gtaaccgcac cggaaacctg tgaatccttg atggattatt taaaaacctt tgatgttatc
    10561 agaccattat tacaaacgcc tcaggcttta acattggctg cttatgatgt tgtgaagcag
    10621 gctgcccttg aaaatgtcat ctacattgaa attcgatttg ctcctgagtt gtcaatggat
    10681 cagggcttga ccgccactca ggtggtagag gcagttttaa aaggactcga gcaaggacaa
    10741 aaagagtttg gcattgtcgc taaggctatt gtgtgtggca tgcgtcagtc ctcactagac
    10801 attagcagag agatttttgc aaatgtctta gagtgggcca ataaaggctt ggtaggcttt
    10861 gattttgcag gcaacgagct ggactttcct ccagctgtct tagcagattt gatcaaagag
    10921 acgcaggcct atgggttacc atttacgctt catgctggtg agtgtggctg tccaaactat
    10981 attgttgatg ctattgattt aggtatcaaa cgcttagggc atgtgacggc cattcataac
    11041 caaaaggatt tattggccaa gtttatcgcc aatgatgtga cagcagagct gtgcttcact
    11101 agtaatctac aaaccaaggc tgctaggact gttgaggact ttccttatat gcagctaagg
    11161 caggctggcg ctaaattatc cattaacaca gacaatcgaa cagtatccga taccaatctg
    11221 acaaaggaat atgaactgtt tgtcaagcac tttgagacaa gcgtcacaga ctttttagag
    11281 cataatcgtg atgctattaa ggctagtttt gccagtccgg ctgaaaaaga agctttattg
    11341 gatcgtttgg aaaaggctta tcagtcttac atcaagaaat aatgcttttc ttggcaaagt
    11401 atgataaaat atactgacat ttagttattt tgggaggaaa ttatggcatt agccaaaatc
    11461 gtttatgcca gcatgacagg aaatactgaa gaaattgctg atattgttgc taataaattg
    11521 caagaattgg gacatgatgt tgaggttgac gagtgtacaa cagttgatgc ttcagagctt
    11581 gaggctgctg atatggcaat cgttgcgacc tatacctatg gtgatgggga cttaccagat
    11641 gagattgtcg acttttatga ggacttgcag gatttggatt tgtcaggcaa gatctacggt
    11701 gtcgtgggct ctggtgatac cttttatgat tatttctgca aatcagttga tgattttgac
    11761 gaacagctcg ctgccactgg tgccactaag ggagctgact cggttaaggt tgatttagct
    11821 gctgaggaag aggatattgc tcgcctagaa tcctttgctg agcaaatgtc acaggcatta
    11881 gaggcataag taagactttt gatacagatt ggtaaaacgg tcagtggagg cttgcgtttt
    11941 ttaccaccaa atgcatgaaa aactgatatt ttctgatcgt tttttcatga ctatgtgctc
    12001 tttttcaaga aaagtcatgc cattattagc ctgaatgcaa acaattgata gtgtcaaaat
    12061 gttgatcata tagtaaaaaa atgcatgtga ctagaaagca gttacatgca ttttcgtcat
    12121 gcgtttgtcg tgaggcattt tgggggttac ttgcttactg agctgaaatt cactataata
    12181 aaaagataaa taaagaaaag aagaagttag gtgaatgatg ggattagaga ccatacgaca
    12241 agacattaat gctgttgatc gtcagttgat tgctttgctg gaaaagagaa tggtcttggc
    12301 tgaccaagta gcggcctata agcaggtaca tgatgtgcca gtgcttgatc aagagcgaga
    12361 ggctgaggtc ctaaggagcg tgtcacagca gattcggcat aaggcctttg agcctgccat
    12421 tcttgagcta tttaagacaa ttatggcagt atcaaggcgt tatcaggctg agcaaatagc
    12481 ggttggttca aatgatgatg aagcctatta aaaacaatca agacatcagt ataggtgata
    12541 atgtctattt ggcttttgca gccctgctcg ttggggtggt ggtaggtgtg atagatactg
    12601 tttttggaca aggcttgttg ctcttgtctg ctgttcgtga tgctcatctc atttacctgt
    12661 taccctgctt agctcttgct ggacttgtga ttgtgttctt atatgagcaa tatggccaaa
    12721 tcgctaagca ggggatgggc ttagtttttg atgtggggaa tggtgaaaaa acaagactac
    12781 cactggtgtt gattccgttg attatcctct caacctggct gacgcattta tgtggaggca
    12841 gtgctggtcg tgaaggcgta gcggttcaaa ttggagcgac aggtcacatt tttttggacg
    12901 tcttagacat cttaaggaca agtcacagct gtttttagtc atgggaatgg ccgcaggctt
    12961 tgcgggctta tttcaaacgc caatgacagc ggttgttttt gccttagagg tcctgttgct
    13021 aggaaatata agctatttag ccttgctacc ttctcttata gcagccttta ccgcctcttg
    13081 gacctctcat tgcctaggct tagaaaaatt ttcagtcccg atagccaagg ccttgaaaat
    13141 caccccgata acctttggga aattagtgct actaggcctt atttttggct tggctggtaa
    13201 tctttttgcc tccttgttag caagggctaa gccatacatt gcagcaaggc tgccaaatcc
    13261 ttattatcgt gtgttgcttg ttggtggttt tctatcgctt agcctgctgc tgtgccatta
    13321 cgggcgctat agtggcctag ggactaactt aattacagcg gcctttagtc atcagcctat
    13381 tgctaattat gattggctat taaagctctt gtttaccatt atcactctct cggctggctt
    13441 tcagggcggt gaggtcactc cactttttgc tattggtgcg gctttaggaa ttgtcctagc
    13501 accatggctt ggcttgccgg ctcagttggc tgcagccctt ggctatgctg cggtatttgg
    13561 cagtgccacc aatacctttt tagccccgat atttgttgga ttagaggttt ttggtgcaac
    13621 aaacgcaact gcttacttta tcgtgatagc ctttgcttat atggtgagcc gaaggcattc
    13681 aatctacact aagcaaaggg tgaccactag catcgcttcc tagtgtcttg gtcagttttt
    13741 tggagaaaat agctttacaa gtggggctta ttttgttaca ataggctccg tgtgtaatgg
    13801 acgcacaaaa attacggcta atccgctaag actcgcgctt aagattagta agataaggag
    13861 aataaacaat gaatccatta attcaaagct tgacagaggg tcaacttcgt actgatattc
    13921 ctagcttccg tcctggtgac actgttcgtg tgcacgcaaa ggttgtcgaa ggatctcgtg
    13981 aacgtatcca gatctttgag ggagtagtca tttcacgtaa aagtcaaggt atctcagaga
    14041 tgtatactgt tcgtaagatt tctagtggta tcggtgtaga gcgtaccttc ccaattcaca
    14101 caccacgtgt tgaaaagatt gaggttgtgc gtcatggtaa ggttcgtcgt gctaagcttt
    14161 actacctacg tgccttgcaa ggtaaggcag cgcgtatcaa ggaaattcgt cgctaaaaag
    14221 agcatacgag aggtttttca ctgtcttatg aaaggactgc tggagcagca gggtctttgg
    14281 gacaagcttt ttttcgcagg tatgtgaacc tacgctcaat tcaagacata tcaaaggctc
    14341 attctatgat agagtgggct ttttgattgt gatcatgctt tagtgcctaa ataaatgaca
    14401 gcagcctgac taatgaaagg cttacttgac tttggaaatg ctcaaggctt gcgctaccag
    14461 atagaagctg acatcatgcc atagcagtca aggggaagaa ggactagatt ttttggcgag
    14521 gtgttgatct gtgaccctga tgttgttggg aatatgagag taatttaaaa tttcgtcttg
    14581 cattctacct ttttctaggt tacaatagac aagtaacctg attagtgaag ctaaaagacg
    14641 tagcgatggg ttctaaaaaa gaatgattct ggcgtttttg gctaacctaa gctgatagct
    14701 ttgctaggca gtgtcttagt catctggtca gtcctgctag tttaacggat aaaacaagcg
    14761 cctcctaagc gctagctgtg ggttcgattc ccgcgcggga cattaaaaac aaagtaaaaa
    14821 gagtctgaga aggtttgagc tgcccctaat tgttagattt ttttctaact cttgaagtgt
    14881 gggtcaaaga ctatttgtct caggactctt tttaattggt ttttactaag ctgcttcatc
    14941 tagttcttca gttgctaagt tgtttccttc ttctgtatgt tggttttcat caagtagcat
    15001 tcctgtgcgg taatctaatg ctgccaaagg tgatacatta tccagaacaa ctgaggttat
    15061 accataatga tcaacggatt ctttgttgcc tcccaatttg atttggagga gctctccgtt
    15121 ttgatcaatt ccaacgtact gtaacactac ttgacgagga actaattcat cattctgata
    15181 aataggagtt accttataat ctagccaaaa gttagggtgt atggctaacc aattgtctag
    15241 tctattttca taataaagca ttcctaaagg atttttatca ctaaaacctg tattaaggta
    15301 ttttgtcata gtaactaaat ttttgggttc atcatttagg ccgctaaact gataaccgac
    15361 tagatgtccg cgatccatta accaagtctt tttccctcta gaattaatga cttgatagtt
    15421 atgccagccg ggaggattaa atctaagcgc ttttcttttg agagttggtt catcttgatc
    15481 tttgagttgt atgtgtgcat aggtggctct ttgtaaatga tcaagatctc ccagagctat
    15541 ttggtatttt ccagtaaacg gtaaaattcc tggtatttcg gtagcttttg ttcccaatga
    15601 tatttccgtt gtatctggga aggttctaag ttttcttgca gattgaacag agttagctgt
    15661 gaaaatagtc agaatagtta acaaaacaat tgttagactt ttccagttac ggcgacgtga
    15721 tttagacata tcaatgccct cctttttttg
//
LOCUS       DARYXW010000047        15097 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.047, whole genome shotgun sequence.
ACCESSION   DARYXW010000047 DARYXW010000000
VERSION     DARYXW010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15097)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15097)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15097
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.047"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(220..1320)
                     /locus_tag="TV191_001214"
     CDS             complement(220..1320)
                     /locus_tag="TV191_001214"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEL1507730.1"
                     /translation="MISSLHRPTVARVDLEAIRANIDHIHQHIPKKVRTYAVVKANAY
                     GHGAVAVSKAVEDQVDGYCVSNLDEALELRQAGIDKEILILGVILASELQLAIKHQLT
                     ITVASLEWLELAKKESVDFSQLHVHVKVDSGMGRIGVRSLAEANQLISILSDMGVQLD
                     GIFTHFATADDSDHAMFDKQLTFFKQLVEQLDKRPALVHASNSATSLWHSETIFNAIR
                     LGIVIYGLNPSGNSLSLPCPLKEALSLESRLVHVKQIQAGDSVGYGASYVAAEPEYVG
                     TLPIGYADGWTRNMQGFKVLVEGEFCDIIGRVSMDQLTIRLPKAYPIGTKVTLIGQQG
                     KQVITATDVADYRGTINYEVLCLLSDRIPREY"
     gene            complement(1317..1673)
                     /locus_tag="TV191_001215"
     CDS             complement(1317..1673)
                     /locus_tag="TV191_001215"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEL1507731.1"
                     /translation="MIVGHGIDLQDISAIEKVYLRNARFARKVLTDKELALFEQFSHH
                     RKMTYLAGRWAGKEAFSKAMGTGIGQLTFQDIEIINDSKGRPVITKSPFQGKAFISIS
                     HSGGYVQASVILEDLA"
     gene            complement(1789..4317)
                     /gene="secA"
                     /locus_tag="TV191_001216"
     CDS             complement(1789..4317)
                     /gene="secA"
                     /locus_tag="TV191_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEL1507732.1"
                     /translation="MSNILRKVIENDKGELRKLEKIAKKVESYADYMESLSDKDLQAK
                     TPEFKQRYQNGETLEQLLPEAFAVVREAARRVLGLYPYRVQIMGGVVLHNGDVPEMRT
                     GEGKTLTATMPVYLNALAGEGVHVITVNEYLSTRDATEMGEVYSWLGLSVGINLAAKS
                     PAEKREAYLCDITYSTNSEVGFDYLRDNMVVRQEDMVQRPLNFALVDEVDSVLIDEAR
                     TPLIVSGAVSSETNQLYIRADMFVKTLDSVDYIIDVPTKTIGLSDSGIDKAESYFNLS
                     NLYDIENVALTHFVDNALRANYIMLLDIDYVVSEEGEILIVDQFTGRTMEGRRFSDGL
                     HQAIEAKEGVRIQEESKTSASITYQNMFRMYKKLAGMTGTAKTEEEEFREVYNMRIIP
                     IPTNRPIARIDHTDLLYATLNSKFKAVVADVKARYEKGQPVLVGTVAVETSDLISKKL
                     VEAGIPHEVLNAKNHFKEAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDELMRRFGTDRIKAFLDRMNNDD
                     EDIVIKSRMLSRQVESAQKRVEGNNYDTRKQVLQYDDVMREQREIIYANRRDVITANR
                     DLGPEIKAMIKRTIDRAVDAHSRTNRKDAIDAIVTFARTSIVPEETIGAKELRGLKDD
                     QIKDKLYQRALEIYDKQLSKLRDQDAILEFQKVLILMIVDNKWTEHIDALDQLRNAVG
                     LRGYAQNNPVVEYQSEGFKMFQDMIGAIEFDVTRTMMKAQIHEQERERAIQYATTTAA
                     QNIQSQAIGADFDSSADFSRVERNDACPCHSGKKFKNCHGRKAF"
     gene            complement(4693..5637)
                     /gene="manA"
                     /locus_tag="TV191_001217"
     CDS             complement(4693..5637)
                     /gene="manA"
                     /locus_tag="TV191_001217"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEL1507733.1"
                     /translation="MSEPLFLTSCMHDKIWGGTKLREVFGYELPTETTGEYWAISAHP
                     NGVSTVSSGSYQGQRLDQLYAERPELFGNPKEKVFPLLTKILDANDWLSVQVHPDDAY
                     GLAHEGELGKTECWYIISAEEGAEIVYGHHASSKQELRAMIEAGNWEELLTRVPVKAG
                     DFFYVPSGTMHAIGKGILILETQQSSDTTYRVYDFDRRDAEGQLRELHIEKSIDVLTI
                     GKPENSTPATLELEHLVSTCLVSNPFFTVYKWEIDQAVSMKQSAPYLLVSVLAGQGSL
                     TIDQAVYELQKGMHFILPNDVTSWSFDGQLEMIVSHPN"
     gene            complement(5753..6637)
                     /locus_tag="TV191_001218"
     CDS             complement(5753..6637)
                     /locus_tag="TV191_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEL1507734.1"
                     /translation="MKTLLGSIEAGGTKFVCAVGDRDFAVVDKVQFPTTSPKETIERT
                     IAYFKQFEADLASIAIGSFGPIDIDPKSATYGYITTTPKPGWANVDLLGQLTAAFAIP
                     FYVTTDVNSSAYGEAISRPDVDSLVYYTIGTGIGAGAIQKGEFIGGLGHTEAGHTYVM
                     QHLDDVANAFLGVCPFHRGCLEGMAAGPSLEARAGIKGELLDQKAAVWDIQAFYIAQA
                     AVQATLLYRPQVIVFGGGVMAQEHMLVRVQEAFTRLINGYLPVADVREYLVTPAVAGN
                     GSATLGNFALAKLIAEKS"
     gene            complement(6994..10050)
                     /locus_tag="TV191_001219"
     CDS             complement(6994..10050)
                     /locus_tag="TV191_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEL1507735.1"
                     /translation="MEKQVLVKKTLKCVCAAALMVAILAAQHDSLIRVKAEDKVVQTS
                     PSVSAIDDLHYLSENSKKEFKEGLSKAGEVPEKLKDILSKAQQADKQAKVLAEMKVPE
                     KIAMKPLKGPLYGGYFRTWHDKTSDPAEKDKVNSMGELPKEVDLAFVFHDWTKDYSFF
                     WQELATKHVPTLNKQGTRVIRTIPWRFLAGGDHSGIAEDTQKYPNTPEGNKALAKAIV
                     DEYVYKYNLDGLDVDIERDSIPKVNGKESNENIQRSIAVFEEIGKLIGPKGADKSRLF
                     IMDSTYMADKNPLIERGAQYIDLLLVQVYGTQGEKGDWDPVARKPEKTMEERWESYSK
                     YIRPEQYMVGFSFYEENAGSGNLWYDINERKDDHNPLNSEIAGTRAERYAKWQPKTGG
                     VKGGIFSYAIDRDGVAHQPKKVSDDEKRTNKAIKDITDGIVKSDYKVSKALKKVMEND
                     KSYELIDQKDFPDKALREAVIAQVGSRRGDLERFNGTLRLDNPDIKSLEGLNKLKKLA
                     KLELIGLSQITKLDSLVLPANAKPTKDTLANVLEAYGSAKKEETKAIPQVALTISGLT
                     GLKELNLAGFDRDSLAGIDAASLTSLEKVDLSSNKLDLAAGTENRQILDTMLATVTKH
                     GGVSEKTFVFDHQKPTGLYPDTYGTKSLQLPVANDTIDLQAKLLFGTVTNQGTLINSE
                     ADYKAYQEQEIAGHRFVDSSYDYKAFAVTYKDYKIKVTDSTLGVTDHKDLSTSKEETY
                     KVEFFSPTNSTKPVHEAKVVVGAEKTMMVNLAEGATVIGGDADPTNAKKVFDGLLNND
                     TTILSTSNKASIIFELKEPGLVKYWRFFNDSKISKADCIKEAKLEAFVGHLEAGSKVK
                     DSLEKSSKWVTVSDYSGEDQEFSQPLNNIGAKYWRITVDTKGGRYNWPSLPELQIIGY
                     QLPAADLVMAMLATAEELSQQKDKFSQEQLKELEVKIAALKAALDSKMFNADAINAST
                     ADLKAYVDKLLADRTDQEKVAKAAKVEQPVATDIKENTEPENPKTD"
     gene            complement(10279..12162)
                     /locus_tag="TV191_001220"
     CDS             complement(10279..12162)
                     /locus_tag="TV191_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEL1507736.1"
                     /translation="MDNHQIAKEVIEALGGRENVRSVAHCATRLRVMVHDEGKINKEK
                     AEAIDKVKGAFFNSGQYQLIFGTGTVNSIYDEVVALGLPAALAGEQKEQVVKSGNAFQ
                     RAIRTFGDVFVPIIPAIVAIGLFMGVRGLLTQPAVMEFFGIHDYGDNFLMYTRILTDT
                     AFVYLPALVAWSAFRVFGGNPIIGIVLGLMLVSNELPNAWVVASGGDVKPLTFFGFVP
                     VVGYQGTVLPAFFVGLVGAKLEKWLHKRVPDALDLLATPFLTFAIMSALGLFVIGPIF
                     HSLENLVLAGTQAVLGLPFGIAGLVIGGVQQLIVVTGIHHIFNFLEAQLVANTGKDPF
                     NAYLTAATAAQAGATLAVAVKTKSAKLKGLAFPSALSALLGITEPAIFGVNLRYPKVF
                     VSGLIGGAAGGWVAGILGIAGTGFGITVLPGALLYLNGQLLQYLVTLLVGLGLAFVIA
                     YIWGFKDKSDQEAPATQVKSEPAQKASAAEELLSPVAGELIDLSSVADPVFSSGSMGQ
                     GVAIKPEGRILCSPVDGRVEAALETGHAYVIKSDKGAEILLHIGIDTVSMAGEGFETF
                     VKVGQMVKAGDALGSFDIARIQQAGLDTTTMLLVTNSADVHAVQILAQGKVTVGSPVI
                     LVK"
     gene            12439..13878
                     /locus_tag="TV191_001221"
     CDS             12439..13878
                     /locus_tag="TV191_001221"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HEL1507737.1"
                     /translation="MDLPRSIRYRPYQEWSKEAYQAIQQKVAQSLWRSHFHIEARTGL
                     LNDPNGFSYFAGSFQLFYQNWPFGAAHGLKQWVHTTSTDLVHFTETKTRLLPDHQNDS
                     HGAYSGSAYPIGDKLFLCYTGNVRSKDWVRHPLQIGAWMDQSGHITKCEQVLIDKPDD
                     VTEHFRDPQLFTYQDQLYAIIGAQNLQQQGIIKLYKANNNDVTSWQFVADLDFDDSGT
                     AYMIECPNLVFIEDKPVLIFCPQGLAKSELDYQNIYPNTYKVFQTFDPKRRKLLGGGP
                     IQNLDFGFEAYATQAFNSPDGRVLAVSWIGLPDIDYPTDKYAYQGALSLVKELRLKNG
                     RLHQAPVPALSKLRDKAQPFQNKKNSSNCYELALTIEAQQATELLLFADTQHKGLKLT
                     VDTCKGQLTIDRSKAGAQYAQEFGAKRSCQIPVNRATLNIYVDKSILEIFVNQGEAVL
                     TSRVFPNEGQSGIELLKGQVSGYYYEMRY"
     gene            13883..14848
                     /locus_tag="TV191_001222"
     CDS             13883..14848
                     /locus_tag="TV191_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1507738.1"
                     /translation="MVAKLTDVAALAGVSPTTVSRVINKKGYLSQKTIDKVNKAMREL
                     GYKPNNLARSLQGKSPQLIGLIFPNISNIFYAELIEHLEIELFKQGYKAIICNSENNP
                     IKERDYLEMLAANQVDGIISSSHNLGIDDYERVEAPIVAFDRNLAPHIPIISSDNFEG
                     GKLAAKTLQKHGCQKMIMITGNDHSDSPTGLRQLGFNYQLKKGADIIKLPNDLSSIRR
                     EMEIKSILATRRPDGIFASDDLTAILIMKVAGQLGIAIPDNLKLIGYDGTAFIEHYFP
                     QLTTIKQPIKEIASLTVEVLLKKIGNEKTSKDYVLPITLLPGGSL"
BASE COUNT         4306 a         3770 c         2859 g         4162 t
ORIGIN      
        1 tgaagcaaaa taaaatgcaa gattttttgt attaatgcct taatactcgg ataaaggtaa
       61 gggccttttc ttattctttt tcttaacccg cagaaaaaca agacctgtct tgatctgctc
      121 tatctatgct gttagcctga ggtctcaaga cctttacagg actaatcatt tgaaagacag
      181 ccttgaggcc agtcaatagt tgagcctagg ctcaatttcc taatattctc taggaatacg
      241 atcactcagc aagcaaagca cctcataatt aatcgtacct ctataatcgg caacatcggt
      301 tgctgtgatt acttgtttac cctgctgtcc aatcaaggtc accttagtgc cgataggata
      361 ggctttaggc aaacgaatgg tcaattggtc catcgacaca cgaccaataa tgtcacaaaa
      421 ttccccttct accaatacct taaagccctg catatttcga gtccaaccgt cagcatagcc
      481 gataggtaag gtcccgacat actctggttc tgctgctaca tagctagctc catagccaac
      541 gctatcccct gcctgaattt gcttcacatg aaccaaacgt gattctaagg acaaggcttc
      601 ctttaaggga caaggtagac tcaagctatt gccgcttgga ttgagtccat agataacaat
      661 accaaggcga atggcattaa aaattgtttc actatgccaa aggcttgttg cagagttgct
      721 tgcatgcact aatgcaggcc tcttatctag ctgctccacc aactgcttga aaaaggtcag
      781 ctgcttatcg aacatggcat ggtcagagtc atctgcggtt gcaaaatgcg tgaaaatccc
      841 gtcaagctgc actcccatat cggataagat tgagatgagc tgattggcct cagcaagcga
      901 cctgacacca atgcgcccca ttcccgagtc aaccttgaca tgcacatgaa gctgactgaa
      961 atcaaccgat tcctttttgg caagctctag ccactctaag ctggccactg ttatcgtcag
     1021 ctgatgctta atggctagct gcaattcact tgctaaaatc acccctaaaa taaggatttc
     1081 cttatcaatg cctgcctgac gtaattccaa ggcttcatca aggtttgata cgcaatagcc
     1141 atcaacctga tcctcaactg ccttggacac tgcaactgcc ccatgaccat aagcattggc
     1201 cttgacaaca gcatatgtcc ttaccttttt aggaatatgc tgatgaatat ggtcaatatt
     1261 tgctcgaata gcttctaagt caactctagc tactgttggt cgatgtaagc ttgaaatcat
     1321 gctaaatcct ccaaaataac acttgcttga acatagcccc cactatgtga aatactgata
     1381 aaggccttac cctgaaaggg agattttgta atgacgggac gccctttgct gtcattgata
     1441 atttcaatat cctgaaaggt tagctggcca atccctgtcc ccattgcctt tgaaaaggcc
     1501 tccttaccag cccagcggcc ggccagatag gtcatttttc ggtgatggga aaattgctca
     1561 aacagcgcta gctccttgtc cgtcaaaacc tttctagcaa atctagcatt tctcaaataa
     1621 accttttcaa tagctgaaat atcctgtaaa tctatcccat gtccaacaat catttgcctt
     1681 tattttacca gccttcactt taatttaggg aaacaaatcc taaacaagga gaagccgaga
     1741 acaaatctca gctcctcaca ggttttcaac atggccatca cgctatcctt aaaaagcctt
     1801 acgaccatga cagtttttaa acttcttacc agagtgacaa ggacaagcat cattgcgctc
     1861 gactcttgaa aaatcagctg atgaatcaaa atcagcaccg atagcctgcg actgaatgtt
     1921 ttgtgctgca gttgttgttg catactgaat tgcacgctcg cgctcctgct catgaatctg
     1981 tgccttcatc atggtacgtg taacatcaaa ttcgatagca ccaatcatat cctgaaacat
     2041 cttgaagcct tcactttgat attcaacaac tggattattt tgcgcataac cacgcaaacc
     2101 aaccgcatta cgaagctggt ctaaggcatc aatatgctct gtccatttgt tgtcaacaat
     2161 catcaaaatc agcaccttct ggaattctaa gatagcgtcc tgatcgcgca attttgataa
     2221 ctgcttatcg taaatctcaa gggcacgctg atagagcttg tctttgatct gatcgtcctt
     2281 gaggccacgc aattccttag caccgatggt ttcctctggg acaattgatg ttctcgcaaa
     2341 agtcacgatg gcgtcaatag cgtccttacg attggtacgt gagtgggcat caactgctcg
     2401 atcaatcgta cgcttgatca ttgccttaat ttcaggacct aggtcacgat ttgctgtgat
     2461 aacatcacga cggttagcgt aaataatctc acgctgctca cgcatcacat catcatactg
     2521 caagacctgc ttacgtgtgt catagttatt accctcaaca cgtttttgag ctgactccac
     2581 ctggcgtgac agcattctgg acttgataac aatatcctcg tcatcattgt tcatacgatc
     2641 caagaaagcc ttaatacggt ctgtaccaaa gcgcctcatc agctcgtcct ctaaggagag
     2701 gtagaattgt gactcccctg gatctccctg acgacctgaa cgcccacgaa gctgattatc
     2761 aatacggcgg ctctcatgac gctctgtccc gataacacaa agcccaccga gctctcggac
     2821 accctcaccg agcttaatgt ctgtcccacg accagccata ttggtcgcaa tcgttaccgc
     2881 accacgctga ccagcattca taataatctg tgcttcttta aagtggttct tagcatttaa
     2941 gacctcatgc ggaatgcctg cttctactag ctttttagaa atcaggtcac tggtctcaac
     3001 agcaactgta ccaactagaa cgggctgccc cttttcatag cgagccttaa catctgcaac
     3061 cactgccttg aattttgaat tcaacgttgc ataaagaagg tctgtgtgat caatacgagc
     3121 aataggacgg ttggttggaa tcggaataat acgcatgttg taaacttcgc ggaattcctc
     3181 ttcctccgtt tttgctgtac cagtcatacc cgccaatttc ttatacatac ggaacatgtt
     3241 ttggtaggta atagaggcac ttgtttttga ttcctcttga atacgaacgc cctcttttgc
     3301 ctcaatagct tggtgtaagc catccgaaaa gcgtcgtccc tccattgtac gacctgtaaa
     3361 ctggtctaca atcaaaatct cgccttcctc gctaaccaca taatcaatat ccaaaagcat
     3421 gatataatta gcacgaaggg cattatccac gaagtgggtc aaggcaacat tttcaatatc
     3481 gtataggttg ctgaggttga aatagctttc tgccttatca atacctgagt cgcttaggcc
     3541 aatcgtcttg gtcggaacat caatgatgta atccactgaa tccaaggtct tgacaaacat
     3601 gtctgcacga atatagagct gattcgtttc tgagctcaca gcaccagata caatcagagg
     3661 tgttcttgcc tcgtcaatca aaacagagtc aacctcatcg accaaggcaa agttcagtgg
     3721 tcgctgaacc atgtcctctt gacgaaccac catattatca cgcaggtagt caaagcctac
     3781 ctcagagttg gttgagtagg taatatcaca tagataagcc tcacgctttt cagctggtga
     3841 tttggctgct aggttgatac cgactgaaag ccctagccag ctatacacct ctcccatctc
     3901 tgtcgcgtca cgagttgaca agtattcatt aacagtgata acgtgtaccc cttcgccagc
     3961 aagggcatta aggtaaacag gcatggtcgc tgtaagggtc ttaccttcac cggtacgcat
     4021 ctcagggaca tctccattgt gcaagacaac cccccccatg atctgaacac gataagggta
     4081 aagtcccagc acacgtctag ccgcctcgcg gacaaccgca aatgcttctg gtaataactg
     4141 ctcaagggtt tccccatttt gataacgttg tttaaattcg ggcgtttttg cttgtaggtc
     4201 tttatctgac aaggactcca tatagtcagc ataggactct acttttttcg caattttttc
     4261 taattttcgt aattcgcctt tatcattttc aatgactttg cgtagaatat tgctcattct
     4321 ctttcctttc gatcgactaa tcattttatt ctaacataaa taggcaggca gttcaagaaa
     4381 tgatcataag atatccatga cagacgcatg aagaaaatca tttattgaaa aagttgtgaa
     4441 aatagcaaaa tagccatttt agggtatttg acagagtgtt tcctgaattg ttatattctc
     4501 cctctataaa cttttcttga aaaatttctt ttctgcaact atcgctatgg ctttcctatt
     4561 tttcagaata agttttcgca ttcagaaata tcttggaaat tttttcttca tgcgtctgtc
     4621 gtgataagat atcagaaaaa gaaaggccgc ttgtccaaac agtctttctt ggtgttttcg
     4681 tgtattctgt acttaattag gatgactgac aatcatttcc agctgaccat caaagctcca
     4741 tgacgtcaca tcatttggca ggataaaatg catacccttt tgaagctcgt aaacagcttg
     4801 atcaatcgta aggcttccct gaccagctag cacactgaca agcaggtaag gggctgattg
     4861 cttcatgctg actgcttgat caatctccca tttgtaaact gtaaagaagg gattagatac
     4921 taagcaggta gagaccaagt gctcaagttc tagtgtggct ggcgtgctgt tctcaggctt
     4981 gccaatagtt aggacatcga tagatttctc aatatggagc tcacgaagct gaccttcagc
     5041 gtctcgacga tcaaaatcat aaacgcgata ggtcgtgtct gaggattgct gcgtctctaa
     5101 gatcaaaatt cccttaccaa tggcatgcat cgtgccgctt ggaacataga agaaatcacc
     5161 agccttaacc ggaactcgcg tcaacaactc ttcccagttc cccgcctcaa tcatcgcacg
     5221 aagctcttgt ttagagcttg catgatgacc ataaacaatc tcagcgcctt cttcagctga
     5281 aataatatac cagcattccg tctttcctag ctctccctca tgggccagcc cataagcatc
     5341 atctgggtgt acctgaacgc ttagccagtc attagcatct aaaatcttcg tcaacagcgg
     5401 aaagaccttt tcctttggat ttccaaatag ctctggtctt tctgcataaa gctgatctag
     5461 cctttggcct tggtagctac cactgctaac tgtggaaaca ccattagggt gagctgagat
     5521 tgcccaatac tccccagtgg tttcggttgg aagctcatac ccaaacacct ctcttagctt
     5581 tgttccgccc cagatcttat catgcatgca tgatgttaaa aataatggtt ctgacatagt
     5641 aatcctcatt ctcttttcac taacctatgg tgacattctt tgccccaatt ctaccaattt
     5701 caggcacatt ttgcaaatga ctctaggact tttatcaaat aggctcaagt atctagctct
     5761 tttcagcaat cagctttgct aaagcaaaat tcccaagagt ggccgagcca ttacctgcaa
     5821 ctgctggtgt gaccaaatat tctctaacat cagctactgg taaataacca ttaatcagtc
     5881 tggtaaaggc ctcctgaaca cgcaccagca tgtgctcctg tgccatcaca cctccaccaa
     5941 acacaataac ctgaggacga taaagcagcg ttgcctgtac agcagcctga gctatataga
     6001 aggcttgaat atcccaaaca gcggccttct gatcaagaag ctccccctta atccctgccc
     6061 ttgcttcaag gcttggccct gctgccatgc cctctaagca cccccgatga aatggacaaa
     6121 cacccaaaaa tgcattcgcc acatcgtcaa ggtgctgcat aacataggta tgtcccgcct
     6181 ctgtatgacc taacccaccg ataaactcac ctttttgaat agctccagca ccaatacctg
     6241 ttccaatcgt ataataaaca agactgtcaa catcaggtcg agagatagcc tccccatagg
     6301 cagaactatt aacatcagtc gtcacataaa aaggaatcgc aaaggctgct gtcagctgcc
     6361 ctaatagatc tacatttgcc caacctggct tgggtgttgt ggtaatgtag ccataggtag
     6421 ctgacttagg atcaatatca atcggtccaa aggagccaat agcaatacta gccaagtcgg
     6481 cctcaaattg cttaaaataa gcaatcgtac gctcaatagt ctcttttgga cttgtcgttg
     6541 gaaattgcac cttatccaca acagcaaaat ccctatcacc aacagcacag acaaactttg
     6601 tcccgcctgc ttcaatactt ccaagtaatg ttttcatctt ttctccttaa taatagtgat
     6661 aagccctgtg ctggttattc tcacaaggct caaaatccca ccagctaatc agcagctacc
     6721 ttagtagcta aacatcatcg cttgcttcct tgcctcctag aaaagaccaa aaatctggga
     6781 taggactatc tcagattttt gatatgcctt taagagataa ggcaattgat tttaggaggg
     6841 aaaccttggc agcaggagct gccaccaaga agcagcacaa acaattgctt ttaatggtgt
     6901 gttcatcgcc ttatctctaa agcttaatgt gttagcgtaa tgatcagtaa cctcaagcta
     6961 acggccaaga acgacagcct gctcaaggat aagctagtct gtctttggat tttctggctc
     7021 agtattttct tttatgtcag tagccacagg ctgctcaact ttagctgctt tagctacttt
     7081 ttcctgatca gttctatcag ctaaaagctt atcaacataa gccttcagat cagcagtact
     7141 agcgttaata gcatcggcat taaacatctt actatctaaa gcagccttta aggcagctat
     7201 tttgacttcg agctccttaa gctgctcttg agagaacttg tctttttgct gagatagctc
     7261 ctctgcagta gctagcattg ccatcacaag atccgcagcc ggtaattgat aaccaatgat
     7321 ttgaagctca ggaagtgatg gccaattgta acgtcctccc ttagtatcaa ctgttattct
     7381 ccaatatttg gcaccaatgt tgtttaacgg ctggctaaac tcttggtcct ctcctgaata
     7441 atctgaaact gttacccatt ttgatgattt ttccaagcta tcctttacct ttgagccagc
     7501 ttcaagatgg ccaacaaagg cttcaagctt ggcctcctta atacagtcag ctttactaat
     7561 tttgctgtca ttaaagaaac gccaatactt gactaagcca ggctctttaa gttcaaaaat
     7621 gatagaagct ttattgctag ttgacagaat tgttgtatca ttattgagca aaccatcaaa
     7681 cacttttttt gcatttgttg gatctgcatc accaccaatc acagttgctc cctctgctag
     7741 gttaaccatc atggtttttt ccgcaccaac gacaacctta gcctcatgca caggcttagt
     7801 gctattagta gggctaaaga attcaacctt gtaggtctcc tccttgctag tggataagtc
     7861 cttgtgatca gtgacaccta aggttgagtc agtcaccttg atcttatagt ccttgtaggt
     7921 cactgcaaag gctttgtaat catagcttga atcaacaaaa cggtgacctg ctatttcctg
     7981 ctcctgataa gccttatagt cagcttcgct attgattagc gtgccctgat tggtaactgt
     8041 tccaaataaa agcttagcct gcaaatcaat tgtatcattt gctactggta actgaaggct
     8101 cttagtgcca taagtatcag gataaagacc agtaggcttt tgatgatcaa atacaaacgt
     8161 cttttcgcta acaccgccat gcttagtcac tgttgccagc atggtatcaa gaatctgacg
     8221 attttccgta ccagctgcta agtccagctt attactagag agatccacct tttcaagaga
     8281 ggttaggcta gctgcgtcaa ttccagccaa gctatcacga tcaaagccag caagatttaa
     8341 ttccttcaag ccagttagac cagaaatggt cagagccacc tgtggaatcg ccttagtctc
     8401 ttccttctta gcgctgccgt aggcttcaag aacattggcc agcgtatcct tggtcggctt
     8461 agcatttgca ggtaggacta agctatccag ctttgtgatt tgtgatagac cgattagctc
     8521 tagcttagct agttttttaa gcttattcag gccttctaaa ctcttgatat ccggattgtc
     8581 taagcgcagg gttccattga accgctctaa atcccctctt ctgcttccaa cctgtgcaat
     8641 aactgcttct cgcaaagcct tgtctggaaa atctttctga tcaatcagct cataggattt
     8701 gtcattttcc ataaccttct tcaaggcctt agaaacctta taatctgatt tgacaatacc
     8761 atctgttata tcctttatag ccttgttagt tcttttctca tcatctgaga cttttttagg
     8821 ttgatgcgct acaccatcgc gatcaatcgc ataagagaaa atccctccct tgacaccacc
     8881 tgtcttaggc tgccattttg cataacgctc agcacgagta ccagctatct ctgaatttaa
     8941 cggattatga tcatctttcc tctcattaat atcataccag aggttaccac tgcccgcatt
     9001 ttcctcatag aaagaaaaac caaccatgta ctgctcagga cgaatgtatt tgctatacga
     9061 ttcccaacgt tcctccattg tcttttcagg ttttctagcg actggatccc aatctccctt
     9121 ctcaccttga gtgccataaa cctgcacaag cagcaaatca atatattggg caccgcgctc
     9181 aatcaatggg ttcttgtcag ccatgtaggt gctatccata atgaacaaac gtgacttgtc
     9241 agcgcccttt ggcccaataa gcttgccaat ttcttcaaaa acagcaatag agcgctgaat
     9301 attttcgtta ctctcttttc catttacttt tggaatgcta tcccgctcaa tatcaacatc
     9361 taaaccatca agattatatt tataaacgta ttcatctaca atagcctttg ccaaggcctt
     9421 atttccctct ggagtatttg ggtatttttg cgtatcttca gcaataccac tatgatcacc
     9481 gcctgcaagg aaccgccatg gaatggtacg aatcacacgt gttccctgct tgttcagcgt
     9541 tggcacatgc ttggtcgcca attcttgcca gaaaaagcta taatccttgg tccaatcatg
     9601 gaaaacaaag gctaagtcaa cctccttagg caattctccc atagaattaa ccttatcctt
     9661 ttcagccgga tctgatgttt tatcatgcca agtcctaaaa tagccaccat aaagaggccc
     9721 ctttaaaggc ttcatggcta ttttttcagg aaccttcatt tctgcaagaa cctttgcctg
     9781 cttatctgcc tgctgtgcct tggataaaat atcctttagc ttttcaggta cttctcctgc
     9841 ctttgataac ccctccttaa attctttttt actgttttcc gacaggtaat gtaggtcatc
     9901 aatagcagag actgatggac tagtttgcac aaccttatcc tctgccttga cccttatgag
     9961 tgaatcatgt tgggcagcta atatagccac cattaacgct gcagcacaaa cacatttcag
    10021 tgttttcttg actaacacct gtttttccat tgggacactc ctttattttg ataccaaaga
    10081 atggcaaatc tttgctgaac caaaaatgta agcgcattct ctgcgttcgt ctaaagtata
    10141 gtagacctca tgatcaaaag caatgcacaa agtataggta aaataaaaga aacttaaggt
    10201 cttttaattt ctgtaatttt atggtgaata ttttaatctt acatgtaaaa agagatgaaa
    10261 tcatcaactc ttttcaaatt attttacaag gatcactgga ctgccaacag tcaccttacc
    10321 ttgtgccaaa atctgaacag catgaacatc tgcgctattg gtgacaagca gcatggttgt
    10381 agtatcaagg cccgcctgct gaatccttgc aatatcaaag cttccaagag catcaccagc
    10441 cttgaccatc tgaccaacct taacaaaggt ttcaaagccc tcacctgcca ttgaaacggt
    10501 atcaatacca atatgcagta ggatttctgc tcccttatct gatttgatga cgtaagcatg
    10561 acctgtctca agggcagcct ctaccctgcc atctaccggt gagcagagaa tgcgcccttc
    10621 aggcttgatg gcaacgcctt ggcccatgct tcctgacgaa aagacaggat cagcaaccga
    10681 tgacaaatca atcaactccc ctgcaactgg actaagcagc tcctcagcag cagaggcttt
    10741 ttgcgcaggc tctgatttta cttgggtagc cggtgcttct tggtcactct tgtccttgaa
    10801 tccccaaata taggcaatca caaaagctag accaagccca accaacagtg tcacaaggta
    10861 ctgtagtagc tgaccattaa gatacagcag tgcaccaggc aaaaccgtaa tcccaaagcc
    10921 ggtaccagca atgccaagaa tccctgcaac ccagccacca gctgcgcccc cgataagtcc
    10981 tgagacaaat acctttgggt agcggagatt aaccccaaag atagccggct cagtaatccc
    11041 taaaagagct gacagagctg atggaaaggc taaacccttt aattttgcag acttggtttt
    11101 aacagcaacc gctagagttg ctcctgcttg ggcggccgta gcagctgtca aataagcgtt
    11161 aaagggatcc tttcctgtat tggcaactag ctgcgcctcc aagaaattga aaatatgatg
    11221 gatacctgtc acaacaatca gctgctgaac acccccaata acaaggccgg caatcccaaa
    11281 aggcagacct aaaactgctt gtgtccctgc aagaacaagg ttttccaagg agtgaaagat
    11341 aggcccaatc acaaagagcc ccaaggcact cataatagca aaggtcaaaa acggcgttgc
    11401 caacaaatca agcgcatcag gcacccgctt atgcagccac ttttccagct tggcaccaac
    11461 cagaccaaca aagaaggctg gcaataccgt accttgataa ccaacaactg gaacaaaacc
    11521 aaagaaagtt aagggcttaa catcacctcc tgaggctacc acccaagcat ttggcaactc
    11581 attagagacg agcatcaagc caaggacaat cccaatgata gggttgccac caaataccct
    11641 aaaggctgac caagcaacca aggccggcag gtagacaaag gccgtatctg ttaaaatccg
    11701 agtgtacatg aggaaattgt cgccatagtc atgaatacca aagaactcca taacagccgg
    11761 ctgcgtcaag agaccccgta cacccataaa cagccctatc gccacaatag caggaatgat
    11821 cggaacaaag acatcaccaa aggtacgaat agcccgctga aaggcatttc cagacttgac
    11881 cacttgctcc ttttgctcac ctgccaaagc agctggaagc cctagagcta caacctcatc
    11941 ataaatgcta ttaaccgtac ctgtcccaaa aatcagctga tattggcctg agttgaaaaa
    12001 agcaccctta accttatcaa tagcctctgc tttttcctta ttgatcttac cctcgtcatg
    12061 aaccataacc cgcagccgcg tcgcacaatg agccacactt ctgacatttt cacgaccgcc
    12121 taaggcctcg ataacctctt ttgcaatctg atgattatcc ataccgatag catctccttt
    12181 tttgtctgtt atagtctatc gaaatagctt ttcttgagcc tatccaatat tggcggacct
    12241 accctactgt ccgactcaag atggtctttc aatttactat tgtgaatccg cttcacttct
    12301 tgctatcatt ttaacacgaa tattttttat gtcaagcgtt tgacatatat tttgtttaaa
    12361 ataattaaaa aagttgattt ttagagagaa aacgtttatc atatgaataa aaatgaccaa
    12421 tacctaagga gacctgacat ggatttacca agatctattc gctaccgacc atatcaagaa
    12481 tggagcaagg aagcctatca agcaatccaa caaaaggtgg cccagtcttt atggcgcagc
    12541 catttccata tagaagctcg tacaggtctc ctcaatgacc caaatggctt ttcttatttt
    12601 gctggcagct ttcagctttt ctatcaaaat tggccctttg gagcagctca tggtctaaag
    12661 caatgggtac acaccacatc aactgacttg gtgcatttta cagaaaccaa aactcggttg
    12721 ctgccggatc atcaaaacga tagtcatggc gcttattccg gctctgctta tcctattggt
    12781 gacaaactct ttttatgcta tacaggaaat gtccgcagca aggattgggt acgccaccca
    12841 ctacaaatag gtgcctggat ggaccaatca ggccacatca caaaatgtga gcaggtgctc
    12901 attgacaagc cagatgatgt cacagagcat tttcgtgacc cccagctctt tacctaccaa
    12961 gatcagcttt atgccatcat tggtgcacag aatttgcaac aacaaggtat cattaagctc
    13021 tacaaggcta acaacaatga tgtcaccagc tggcaatttg ttgctgactt ggattttgat
    13081 gactcaggca ccgcatacat gattgaatgc cctaatttgg ttttcattga agataagcct
    13141 gtgcttatct tctgccctca ggggcttgcc aaatcagagc ttgattacca aaacatttat
    13201 cccaatacct ataaggtatt tcagaccttt gatcctaaaa gacgcaagct ccttggggga
    13261 ggtccaatcc aaaaccttga ttttggattt gaagcttatg cgacacaggc ctttaatagc
    13321 cctgatggta gggtactggc agtttcttgg attggcctgc cggacatcga ctacccaacc
    13381 gataaatatg cctaccaggg agcgcttagt ctagtcaagg aattacgact caaaaatgga
    13441 aggctacacc aagcaccagt ccctgctctc agtaagctac gagacaaagc ccagcccttt
    13501 cagaacaaaa aaaacagctc aaactgctat gagctggctt tgaccattga agcacagcaa
    13561 gcaacagagc ttttgctctt tgccgataca cagcacaagg ggctgaaact gaccgttgac
    13621 acctgcaaag gacagctaac aattgatcgc agcaaggcag gcgcccagta tgcccaggaa
    13681 tttggagcaa agcggtcttg ccaaattcct gtcaatcgtg ctacacttaa tatctacgta
    13741 gacaagtcta ttctagagat ttttgtcaac caaggcgaag cagtcctcac gagtcgtgtc
    13801 tttccaaatg aggggcagtc tggcattgag ctgctaaagg gccaggtgag tggctactat
    13861 tatgaaatga ggtactagac aagtggtcgc aaaattaaca gatgttgcag cattagctgg
    13921 tgttagccca acaacagtct cacgtgtgat taacaaaaaa ggctatctgt cccagaaaac
    13981 cattgataag gtgaacaaag ccatgcgaga gcttggctac aagccaaata acctcgcacg
    14041 aagcctgcag ggcaaatccc ctcagctcat tgggctgatc tttcctaaca ttagtaatat
    14101 tttttacgcg gaattgattg agcatttaga aatcgagctc tttaagcaag gttataaagc
    14161 catcatttgc aacagtgaaa acaacccgat caaagaacga gattatttag aaatgctagc
    14221 tgccaatcag gttgacggca ttatctcatc aagccataac ctaggtattg atgattatga
    14281 gcgtgtcgag gcacccatcg tcgcctttga tagaaacctc gctcctcata tccccatcat
    14341 atcctctgat aattttgaag gagggaaatt ggccgcaaaa accctgcaaa agcatggctg
    14401 ccaaaaaatg atcatgatta caggaaatga tcattctgac tccccaacag gtcttagaca
    14461 gctaggcttt aattaccagc tcaaaaaagg cgctgatatt ataaaactgc caaatgatct
    14521 ttccagtatt cgccgcgaaa tggaaatcaa gtctattttg gcgacaagaa ggcctgacgg
    14581 catttttgct tctgatgatt tgacagctat cctcatcatg aaggttgctg gccagcttgg
    14641 catagcaatt ccagataacc tgaagcttat cggctatgac ggtacggctt ttattgagca
    14701 ttatttccca cagctcacca ccatcaagca gccgatcaag gagattgcca gcttaaccgt
    14761 agaagtatta ctgaaaaaaa taggtaacga aaaaaccagc aaggactatg tcttaccgat
    14821 caccctgctt cccggaggca gtctctaaga gcaatagctc ttcttctgtg attagcggct
    14881 ttcccctagc ttctccctta cttggggcac taaagtaaaa accaaagcac gaggtgggaa
    14941 accctagacc accaggatac acccagatag gtccccaaaa gaaagcttga taagcctgac
    15001 cacctaacaa aacctgcaca caaggaaagc ttcctcaagc tgtcctttgt acccttttcc
    15061 taacaatgcc accaaaaaca catgtaacag caagtga
//
LOCUS       DARYXW010000048        15033 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.048, whole genome shotgun sequence.
ACCESSION   DARYXW010000048 DARYXW010000000
VERSION     DARYXW010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15033)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15033)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15033
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.048"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(419..2830)
                     /locus_tag="TV191_001223"
     CDS             complement(419..2830)
                     /locus_tag="TV191_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL1507739.1"
                     /translation="MKKKHIVLGSAVAILLATNAASYQFGMHKALNSSSKDNSIAYID
                     SKDGKKALPKEKTMDQISAEEGISAEQIVVKITDQGYVTSHGDHFHFYNGKVPYDAIL
                     SEELLMTDPNYQFKQSDVVNEILDGYIIKVDGKYYVYLKPGSKRKNIRTKQQIAEQVE
                     KGTKEAKEKGLAKVAHLSKAEVAAVNEARSQGRYTTDDGYIFSPTDVIGDMGDAFLVP
                     HGSHFHYIPKKDLSPSELVAAQAYWNNKQGGKPSVIGGQPLPGQGDQPRPYDIPVNPI
                     HHPAGNLPSVGDPSLSFADKTFGELLDQLHGLDKKYRHVEEDGLIFEPTQVTLANAFG
                     YVIPHGDHYHIIPREQLSALEITLADRYLAGQTQGSPIAKPKPATQDQTAKEVTHQFL
                     GHQIKAYGKGLDGKPYDTSDHYVFSKASISSVDKAGITAKHEEHFHYMGFGELEQEEL
                     DQVAQWLQEHGQADEIARALVQSDGKDMSFDAKHVSRKVTNGGKVGYMMTKDGKEYFY
                     DREHLDLTQIAFAEQELMLKDKQHYIYDIVDTGVQPKLAVEVSSLPMHAGNATYDTWT
                     SFVIPHIDHIHVVPYSWLTKDQIATIKYVMQHPNTRPDVWSNPNHDEAGGVIANVTPA
                     DQRTSMENWQIIHSAEEVQAAIKAGRYAAPDGYIFDPKDVLAEGTFVWRNDSFSIPRV
                     GGRSLRTITKDELSHDEWQKVQELLGNKTSDAAESTIKPTKDQEPSAQDTAADGIEQT
                     KSLFDDIPNYGLDRATLERQINQLAEIAGIKPEYLIFVPEGVKFYDQKGHLMLYDVTT
                     LQQIK"
     gene            complement(2845..3768)
                     /locus_tag="TV191_001224"
     CDS             complement(2845..3768)
                     /locus_tag="TV191_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000755138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HEL1507740.1"
                     /translation="MKRKWIHLTLLLALFSGLVACSKPKEQSKQSRGMTIVTSFYPIY
                     AMTKAVSGELNDVRMIQSGAGIHSFEPSVNDVAAIYDADLFVYHSHTLEAWADDLDPN
                     LKKSKVAVFEASKSLTLDRVTGLEDIEVTDGIDPATLYDPHTWTDPILAGEEALAIAK
                     ELSRLDPKHEAIYTENAQAFQKEAKELADEYTKKFKKTSSKTFVTQHTAFSYLAKRFG
                     LKQLGISGISPEQEPTPRQLTEIQDFVKEYKVKTIFAEDNVNPKIAKAIAKTAGAKVK
                     LLSPLEAAPKNNKSYLDNLRANLEALYQSLK"
     gene            complement(4095..5642)
                     /locus_tag="TV191_001225"
     CDS             complement(4095..5642)
                     /locus_tag="TV191_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1507741.1"
                     /translation="MKKQSLKKVSLLTVTVISSLALAANANTYTTYARDNVVTATSQA
                     AEGFDFVATILDSNGRALEGKTVVLLDTTANPAKQVASAVSNSNGQAIFTQLPLNINL
                     SVSVDGETKGYTVRTSLAGSKEAASFVAKGAGTKEPLYSKNVIDITVRNQDSEPLEGQ
                     TVTLKIRQGQLVGSLVSDKNGKVTFKDRLLDGTFYHYELNGKYIGQVMTKMSVNAYLD
                     TSSSSSSGTSPQSKDTPKQEDGKSSPLEEGFHFVVTALDKEDRVVAGKEVSLTALIDG
                     AKTTIASAKTNADGQAVFTKLPLSRNISVSIDGKLQGYTVRTSESNEHKAAAFYVDGK
                     GTKPVVYSKTPAIVTVYDANGNKLAGQEVVLKNRYGAIRAIGKTDQSGKATFVNQLMD
                     GMFYEIVINGVKIPKKASTGSDVSGFLTKAQIRTDNKLSESERHSKDTKPLGKEPKDP
                     EKDKNVAKPETKSSSNRNVAPKEGKKETKALPRSGESAAPMVAFMGVLLIGLAAVIGL
                     VTKRRSS"
     gene            complement(6267..7148)
                     /locus_tag="TV191_001226"
     CDS             complement(6267..7148)
                     /locus_tag="TV191_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEL1507742.1"
                     /translation="MKKALLIVNPSSGGEKAKEYEALAYDKLASYFDDVDVKHTEKGG
                     DAKRFAHEAAQQRLDSVFVMGGDGTVNEGISGLAEQDYRPKFGFFPLGTVNDLARALG
                     MSLDPEEAINQISFETTSPLDIGKVNDAYFMNVVAIGTLPEAINDVAPEEKTTFGKMA
                     YFMSGFKQLIKNKSYTFQLDIDGKTKEINSTTLLIGLTNSIGGFERILPEARVDDGLL
                     HLIYLKDSNLLETVKALPSLLKGVEASDQTLGYQTFKEATIAMKEGQLSINVDGDEGE
                     ALPITVKVLPQHLQVYR"
     gene            complement(7313..8314)
                     /locus_tag="TV191_001227"
     CDS             complement(7313..8314)
                     /locus_tag="TV191_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1507743.1"
                     /translation="MVTLKDIAALAKVSPATVSRVLNKDQSLSVGQETKHRILTIADE
                     LGYQKHLKATNSPKSKLKIAIVQWYSQEEELNDLYYYAIRIGIEKRAYELDYDIVRYF
                     NNDILRVSDDHAGIIAIGKFSACQIKELEALSQHLVFVDSDTLELGHPCVTTDFDNAV
                     LKVLDYFMSKGIYSIGMIAGEEKTTDGREALVDQRFRTYKNYASEHGIYQPRYVYIGP
                     FSAQSGYELMTQAIEELGDDLPKAFFIANDTLAIGALRALQERGLAVPERVELISFND
                     TPLTRQVFPALSSVTVFTEDMGRMAVDVLNRNILNPERVKTMTILATELTLRDSTIG"
     gene            8455..9627
                     /locus_tag="TV191_001228"
     CDS             8455..9627
                     /locus_tag="TV191_001228"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEL1507744.1"
                     /translation="MDIAQLKQSFTDVFGKEPDAVFFSPGRINLIGEHTDYNGGHVFP
                     AAISLGTYGLARKREDQQLRFFSANFEEAGIIEVDLNQLTFDQADLWANYPKGVLSFL
                     QKAGHLIDTGFELYVFGNIPNGSGLSSSASLELLTGIVAQELFGLDVERLDLIKIGQQ
                     AENHFIGVNSGIMDQFAIGMGADKQALYLDTNTLAYEAVPLDLGDHVIVIMNTNKRRE
                     LADSKYNERRAECEQALEELNALLDIKALGELDAQRFDEYSYLIKDGKRLKRARHAVL
                     ENQRTLQARQALEAGALEQFGRLMNASHVSLEHDYEVTGPELDTLVHTAWEQEGVLGA
                     RMTGAGFGGCGIAIVAKDKVDSFIETVGKAYTKVIGYAPAFYLAEIAQGARLLSRK"
     gene            9631..11115
                     /gene="galT"
                     /locus_tag="TV191_001229"
     CDS             9631..11115
                     /gene="galT"
                     /locus_tag="TV191_001229"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEL1507745.1"
                     /translation="MASLIDTFVRKVIEHSDYTSEDAIYIRNRVLALVGENHVWQETS
                     LTALIALKEALVELAAENGKIGRLPEEKDCLGAELMNMITPIPSVVNRRFWDTYAQSP
                     QQAISDFYQLSQLNDYIKTAAIAKNISFTVPSQYGDMAITINLSKPEKDPKAIAAAKK
                     AKASSYPKCQLCMENEGYQGRINHPARANHRIIRMSLGNEAWGFQYSPYAYFNEHSII
                     FNTEHVPMTISTSTFRQLLDIVDILPDYFVGSNADLPIVGGSILTHNHYQAGRHVFPM
                     EIAKQDKRFTFKGFPDIQAATLNWPMSVIRLRSSNKDQLVQLADTIRLAWRHYSDDSV
                     DIVAYTNQEPHHTITPIARKKEGQFELDLVLRDNHTSEQFPDGVYHPHADVQHIKKEN
                     IGLIEVMGLAILPPRLKEELVEVKKYILNQANQIADYHKDWADQITLRPDLSAITVDD
                     IIQEEVGSVFVRVLEDAGVYKRDQEGQAAFMRFLKSIGIEAIEE"
     gene            11125..12135
                     /gene="galE"
                     /locus_tag="TV191_001230"
     CDS             11125..12135
                     /gene="galE"
                     /locus_tag="TV191_001230"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEL1507746.1"
                     /translation="MTVLVLGGAGYIGSHTVDWLISQREEKVIVVDSLVTGHRKAVHP
                     EALFYKGDLADKAFMRQVFRDNPDIDTVIHFAASSLVAESMADPLKYFDNNTAGMIKL
                     LEVMREAKVKRIVFSSTAAVYGIPKTVPILESAPKCPINPYGQSKLMMETIMTWADKA
                     YGITFVALRYFNVAGAKPDGSIGEDHEPETHLLPIILQTAQGVREQVMIFGDDYDTPD
                     GTNVRDYVHPIDLADAHILAMAYLRQGKPSQVFNLGSQTGFSNRQLLEAARRVTGQAI
                     PAKKAARRPGDPDTLIASSEKARKVLNWKPSYDDIDKIIASAWAWHTKHPKGYDDKAS
                     GS"
     gene            12212..13255
                     /locus_tag="TV191_001231"
     CDS             12212..13255
                     /locus_tag="TV191_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEL1507747.1"
                     /translation="MNIYQDIIEYIDQVPVTQLRLINTNGVEAHLLTLGATLQAFLVS
                     NEKQPKNIILGHDRPSDYLKNPLCAGQTIGRVAGRIKRGSFQLEQQRVCVDTNENGHC
                     LHGGFKGFHKLHWPYDTRQTVDYLEVTFKRDILEADDHFPGDLTVSITYRLDNHNRLS
                     IHFKAHSMRGTSLFNPTNHVYFNLGQTQDLTNHNLYIAASHRIETDNELIPTGQKLAV
                     DQTVYDFRSIKSLYPAIVENNGFDTAFEIDQQAIGTTKPIAVLQDSVSHDQISIYSDR
                     NALVIYTMDSIQDGLYFGRDQGKEGLAREGIAMEAQTLPDAIHHNQFGDIILKEGGTK
                     SYTICLAYEHLPD"
     gene            13556..13699
                     /locus_tag="TV191_001232"
     CDS             13556..13699
                     /locus_tag="TV191_001232"
                     /inference="COORDINATES: protein motif:HMM:NF013921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL1507748.1"
                     /translation="MIFDKDTNLKHKHRHQKFWYMGYYGDTAGKNLKTIAKYISNHYR
                     KIG"
     gene            14334..14474
                     /locus_tag="TV191_001233"
     CDS             14334..14474
                     /locus_tag="TV191_001233"
                     /inference="COORDINATES: protein motif:HMM:NF013753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL1507749.1"
                     /translation="MEPTNKTIKDMKEQAFGFRNFKNFKVKIPNALNITKEETKFISS
                     RA"
BASE COUNT         4329 a         3391 c         3010 g         4303 t
ORIGIN      
        1 aattgtacgg ctgctaacct ttttcctaac ccttttagac accaaaaaac tccccttatc
       61 gtttttagtg attgtttttc actgtccact ttaaagggga ggtctagcta ttaaaggcta
      121 ggcggttttg actggaggac tattaggtgt gaggttaatt ggtaaaaact ctttctgtgc
      181 tgccctcctt aggtcatata gactttcttg gaaccaaaac ccacatatag cctacagaga
      241 tccaatgctt taaaagctat gaggtgctaa gctgctgatc aagtcagctt ctctgactgt
      301 tgctgcaagc aaaagcctac taagcgatct taggctgtga ggcgtaagaa caggtcatca
      361 taccaatagc tttttgggga taagctgtga tttgtatgcc ttagctattt tatagtgttt
      421 atttgatttg ttgcaatgtt gtcacatcat aaagcattag gtgtcctttt tggtcataga
      481 atttgacacc ctctggcacg aaaataagat actccggttt aatgcctgct atttcagcta
      541 actgattgat ctgacgttca agagttgccc gatctaaacc ataattagga atatcgtcaa
      601 ataaagactt ggtctgctct atgccatctg cggcagtatc ttgcgctgac ggttcctggt
      661 ctttggttgg cttaatagtg ctttcagctg cgtctgaggt cttattgcct aataattctt
      721 gaaccttttg ccattcatca tgagataact catctttagt aatggttctt aaagagcgtc
      781 caccaactct aggaatgcta aaggaatcat tacgccaaac aaaggttcct tcagcaagaa
      841 cgtccttagg atcaaaaata tagccatctg gagctgcgta ccgacctgcc ttgatagctg
      901 cttggacctc ttcggcagag tgaataattt gccagttttc cattgaagta cgttgatcag
      961 ctggtgtgac attagcaatg actcctccag cttcatcatg atttgggtta gaccaaacat
     1021 caggacgagt attagggtgc tgcatgacat atttgatggt cgcaatctga tccttagtta
     1081 gccatgaata aggtacaaca tggatatgat cgatgtgagg aatgacaaaa gatgtccatg
     1141 tatcataggt tgcattacca gcatgcatcg gtaggctgga tacctctaca gctagctttg
     1201 gctgaacgcc tgtatcaaca atgtcataaa tatagtgttg cttatcctta agcatgagct
     1261 cttgctctgc aaaggcaatt tgtgttaggt ctaaatgctc acgatcatag aaatactctt
     1321 tgccatcttt tgtcatcatg taaccaacct taccgccatt ggttaccttg cgactgacat
     1381 gcttagcgtc aaaggacatg tctttaccgt ctgattgaac taatgccctt gcaatctcat
     1441 ctgcttgacc atgctcctgc agccattgtg caacctggtc aagctcctct tgctctagct
     1501 caccaaagcc catgtaatgg aaatgctcct catgcttagc tgtgatgcct gccttatcaa
     1561 cagaggaaat agatgcctta ctaaagacat aatgatcact cgtgtcataa ggcttgccat
     1621 ctaagccttt accataagcc ttaatctgat ggccaaggaa ttgatgtgta acctcttttg
     1681 cagtctggtc ttgagtagct ggctttggct tagctattgg actgccctgc gtttgacctg
     1741 ctaggtaacg atcagccaag gttatttcaa gggctgacaa ttgctcacga ggaataatat
     1801 ggtagtgatc tccatgagga ataacatagc caaaggcatt ggcaagggtc acctgagttg
     1861 gctcaaaaat gagaccatct tcctcgacgt gcctgtattt cttatccaag ccatgcaatt
     1921 gatccaacaa ttctccaaag gttttatctg caaatgatag gcttggatct cctactgacg
     1981 gcaaattccc agctgggtgg tgaatcgggt taacaggaat atcatatggt ctaggctgat
     2041 ctccttgacc tggtaaaggc tgaccgccaa taacacttgg ttttccgcct tgcttgttat
     2101 tccaataggc ctgcgctgct actagctcac ttggggataa gtccttttta ggaatatagt
     2161 ggaagtgact gccatggggc actaaaaagg catctcccat gtctccaata acatctgtcg
     2221 ggctaaagat atagccatca tcagttgtat agcgtccttg acttcttgct tcgttaacag
     2281 ctgccacctc tgccttactc aagtgggcaa ccttagccaa gcctttttcc ttagcttcct
     2341 ttgttccctt ttcaacctgc tcagcaattt gctgcttggt acgaatattt ttacgcttgc
     2401 ttcctggctt tagataaaca taatacttgc catcaacctt gataatatag ccatctagaa
     2461 tctcgttaac aacatcagac tgtttaaact gataattggg gtccgtcatt aatagctctt
     2521 cactaagaat agcatcatag ggaaccttac cattgtagaa atggaaatga tcaccatgtg
     2581 aggttacata gccttgatct gtgattttaa caacgatttg ctctgcagag atcccctctt
     2641 ctgcgctgat ttgatccatt gttttttctt tggggagggc ttttttgcca tcctttgaat
     2701 caatataggc aatgctatta tctttagatg aggaatttag agccttatgc attccaaact
     2761 gatatgaagc agcattagta gccaataaaa tggccacagc tgatcctaaa acaatatgct
     2821 tctttttcac gttttcatct ccctttattt taagctttgg taaagagctt ccaaattagc
     2881 tctcaaattg tctagatagg acttgttgtt tttgggcgct gcctctagtg gactgagcag
     2941 cttgaccttt gctcctgctg ttttagctat cgccttagca attttaggat taacattatc
     3001 ctctgcaaaa atcgttttta ccttatattc tttaacaaag tcttgaattt cagttagttg
     3061 gcgaggagta ggctcttgct ctggcgaaat accagaaata cctaactgct ttaagccaaa
     3121 gcgttttgct agataagaaa aggctgtgtg ctgtgtgaca aaggttttag atgatgtctt
     3181 tttaaacttt ttagtgtact catcagccag ctcttttgct tccttttgga atgcttgagc
     3241 attctcagtg taaatggcct catgcttagg atctaaacga ctgagctcct tagcaatagc
     3301 gagtgcttct tcacctgcta aaataggatc tgtccaggta tgaggatcat acagggtagc
     3361 agggtcaatg ccatctgtca cctcaatatc ctccaaacca gtaacacgat ctaaggttaa
     3421 agatttggaa gcttcaaaaa cagcaacctt tgatttcttc aaattaggat ccaaatcatc
     3481 agcccaggcc tctagggtgt gagagtgata aacaaataaa tcagcatcgt aaatggcagc
     3541 aacgtcattt acagatggct caaaggaatg aatacctgcc cctgactgaa tcatccgaac
     3601 atcgtttagc tcaccagata ccgcctttgt catggcgtaa ataggataaa agctagtgac
     3661 gatcgtcatg cctcttgact gcttgctttg ctccttgggc ttgctacagg caacaagacc
     3721 tgaaaaaaga gcaagcaaca gtgttaaatg tatccatttt cttttcatat aatctccttt
     3781 gctcattaac cagttatgaa ccggttaatt ttaacagctt tagatgtatt tgtcaaattt
     3841 tttaataaaa aataaaagcc attaaaacga tggcttaatc agcccctaac ctgcttaacc
     3901 tttataagaa gccatagctc tatgataaac tgtggtctgt gacgcatgac ctcactgtct
     3961 gttatcttac tgttgcatga tacgtttaaa aaagatttag ccttcttttt ttagattgta
     4021 gaacggcgct gaacaatcac ttaaccgtca aaaaaacgcc ttgatagctg caagacgttt
     4081 ttacttattt ggttttagct agagcgacgt tttgtcacaa gaccgatgac agctgcaagg
     4141 cctattaata gaactcccat gaacgctacc atcggcgctg ctgattcacc agatcttggc
     4201 aaagccttag tctctttttt accttcttta ggggctacat tacggtttga cgaggacttg
     4261 gtttctggct tagcgacatt cttatccttt tcaggatcct ttggctcctt gcctaagggc
     4321 tttgtgtctt tagaatggcg ctcagactcg ctgagtttat tatcggttct gatttgagct
     4381 ttggttaaaa agccgctgac atcactaccg gtagaggctt ttttaggtat cttgaccccg
     4441 ttgataacaa tctcataaaa cataccgtcc atgagctgat tcacaaaggt tgccttacct
     4501 gattgatcag ttttgcctat tgccctgata gctccgtatc gatttttcag cacaacctct
     4561 tgccctgcca acttatttcc attggcatca taaacagtta ctatggctgg tgtcttagag
     4621 taaacaacag gctttgttcc tttaccgtcg acataaaaag cagcagcctt atgctcatta
     4681 gactcactcg tgcgaacagt atagccctgt agcttaccat caattgagac actgatatta
     4741 cgtgatagtg gtagtttggt aaagactgct tgaccatcag catttgtctt tgctgaagca
     4801 attgtcgtct tagcaccgtc tatcagagca gtcaagctta cctccttgcc tgcaacaacc
     4861 ctatcctctt tatctagggc agtgacaaca aaatgaaagc cttcctctag cggacttgac
     4921 tttccatcct cctgcttagg agtgtccttg gactgaggtg acgtacctga tgacgagctt
     4981 gatgaggtat caaggtaagc attaacagac atttttgtca tgacctgccc tatatactta
     5041 ccattaagct cataatgata aaaggttccg tccaacaaac gatccttgaa ggttaccttt
     5101 ccatttttat ctgagacaag acttcccacc agttgaccct gacgtatttt tagggtgact
     5161 gtttgccctt ctaagggctc actatcttga tttcggaccg taatatcaat gacattttta
     5221 ctataaagag gctcctttgt ccctgctccc ttagcgacaa agcttgctgc ctctttagat
     5281 ccagcaagac tggttctcac tgtatagccc ttggtttccc cgtcaacaga aacactcaaa
     5341 ttaatgttta agggtaattg agtaaaaata gcctgaccat tgctgttaga gacagcagaa
     5401 gctacctgct tagcgggatt agctgtcgtg tctaacaaga caactgtttt tccttcaaga
     5461 gcacgaccgt tgctatcaag tatcgtggca acaaaatcaa aaccctcagc cgcttgcgac
     5521 gtcgcagtga caacgttgtc tctggcataa gtcgtatagg tattggcatt ggctgccaag
     5581 gccaagctag atataacagt aaccgttaaa agactgactt ttttcaatga ctgtttcttc
     5641 ataaaaaagc tcctttattt tgattaacta gcctagtttt aatgggaaat atccccttga
     5701 taccctttct gaggtgatag gaacagcagc aatctctctt agcctatgat gcctaagctt
     5761 taaagctaag ttttcaaagt ccacctaagg ggctacatgc cacaacaaaa agcatcagat
     5821 gaacagacat ctagaggcaa cagccgatct aagataatag ttagtagcca ttttagctac
     5881 tctcaaggct gtcgccgcag tgatgatgtg attgtctatg ctttttaata aaacttaact
     5941 agttaagatt tttgtgctgc tatcctatca aataaccccc gccaagtcaa caacaatgct
     6001 cataccacag caagcaaagc attttgatga tgactgaaca gccaaatcag ccaagcccca
     6061 ggcagcaaaa aagaggattc aaaccaaatc ctctctctac taagcctgct gctgttaacg
     6121 tatcatgcta aaggcaaatg gtatagccac gctgatatga aggtctgatt aacagctacg
     6181 acggacacgc ttgttaaggc taccattgct aatcacacta ggtcatatcc tccaccgtat
     6241 aagaatgact aacttcatta ttcagattaa cgatatacct gcaggtgctg aggaagtacc
     6301 ttgacagtga ttggtaaggc ctcaccctca tcaccgtcca cattgataga tagctgtcct
     6361 tccttcatgg caatagtggc ctccttgaag gtttgatagc caagtgtttg atctgaagcc
     6421 tcaactccct tcaataggct aggaagggcc ttcaccgttt ctaatagatt gctatccttc
     6481 agatagataa ggtgcagcaa accatcgtcc acacgtgcct ctggcaaaat ccgctcaaag
     6541 cccccgattg aattggtcaa gccaatcaag agtgttgtgc tgttgatttc ttttgttttg
     6601 ccatcaatat ctagctggaa ggtatagctt ttatttttga tcagctgctt aaagcctgac
     6661 ataaaataag ccattttccc aaaggtcgtc ttctcctcag gggcaacatc attgatcgcc
     6721 tctgggagcg tccctatggc aacaacattc ataaagtaag catcgttgac cttaccaata
     6781 tccagaggac tggttgtctc aaagcttatc tgattaatcg cttcctctgg gtctaacgac
     6841 atgcccaagg cacgtgccaa atcattgact gttcctagag gaaaaaagcc aaacttaggg
     6901 cgatagtcct gctctgcaag cccgctgatc ccttcattga ctgttccatc acctcccatg
     6961 acaaagacac tgtccagccg ctgctgggct gcctcatgag caaaccgttt ggcatctcct
     7021 cctttttcag tgtgcttaac gtcaacatca tcaaaatacg aagctagttt atcataggct
     7081 aaggcttcat attccttggc tttctcacca cctgagctag ggttaacaat caatagggct
     7141 tttttcattt atgatatcct acattttcta ttatatttca cgactattat aatcattatt
     7201 caaaacatcg tcaaataata ctcactatgt cattagtcag tcttaaagct tctaatatgg
     7261 ttgccgtcta gtgtttcatt ttactgaact ctttacccag ctagctcaat gcctaaccaa
     7321 tcgtgctgtc tcttaaggtc aactctgtcg ccaatatcgt catggtcttg acacgttctg
     7381 ggttaaggat attcctatta agcacatcaa cagccatacg tcccatatcc tctgtaaata
     7441 cagtcacact agaaagcgca ggaaagacct gtcttgttaa aggagtatcg ttaaaggaga
     7501 taagctcaac acgctcaggc accgcaagcc ctctttcttg gagagctctt agagcaccta
     7561 ttgcaagggt atcattagca ataaaaaatg ctttaggcaa atcatcacct agctcctcaa
     7621 ttgcctgtgt cataagctca tagccagatt gtgctgaaaa aggaccgata tagacatacc
     7681 tcggctgata aatcccatgc tcagaggcat aatttttata ggtgcgaaag cgctggtcca
     7741 ctaaagcttc tctaccgtca gttgtctttt cctcaccagc aatcatgcca atgctataaa
     7801 tccctttgct cataaaataa tcaagaactt tcagcactgc attgtcaaag tcagttgtga
     7861 cacaggggtg gcccaattca agcgtgtcac tatcaacaaa caccaaatgc tgggataagg
     7921 cttcaagctc cttgatttga caagcgctaa actttccaat agcaataatc ccggcatggt
     7981 catctgaaac cctcaaaatg tcattgttga aataacgaac aatatcataa tccaattcat
     8041 aagctctttt ttcaatgcca atgcggatcg cataatagta gaggtcattg agctcctctt
     8101 cttgagaata ccattgaaca atagctattt ttagctttga tttagggcta ttcgtcgctt
     8161 ttaaatgctt ttggtagccc agctcatcag caattgtgag aatgcggtgc tttgtctctt
     8221 gaccaacaga caagctttgg tccttattta aaactctaga aacagttgca ggagaaacct
     8281 ttgccagagc tgcaatatcc ttaagcgtta ccatatcaaa ccttctttct gatttcttct
     8341 agtatatcac aagcattttc aaaagcaata tttagtaaaa ttttagtaaa aatgttgacg
     8401 agcagcttag cgaagcgtaa aatcaagcta tcaacatcgt taaaggagcc gctaatggat
     8461 atcgcgcaac ttaagcaaag ctttactgac gtttttggca aggagccaga tgctgtcttt
     8521 ttctcaccgg gtcgcatcaa cctcattggt gagcacactg attacaatgg tggacatgtc
     8581 tttccagctg ctatcagtct gggaacctat gggctggccc gcaagcgtga ggatcagcag
     8641 ctgcgctttt tctcagcaaa ttttgaagag gctgggatta ttgaggttga cttaaatcag
     8701 ctgacctttg atcaggctga cctttgggct aattacccta agggagttct ctcctttttg
     8761 caaaaagctg ggcaccttat tgatacgggc tttgagcttt acgtttttgg caacattcca
     8821 aatgggtctg gtctgtcctc ctcggcatca ctggagcttt tgacaggtat tgtggcacaa
     8881 gagctgtttg ggcttgatgt ggaacggtta gatctgatta aaatcggtca gcaagctgaa
     8941 aatcacttta tcggggtgaa ttcaggtatc atggaccaat ttgccatagg catgggagct
     9001 gataagcagg ctctatacct tgataccaac accttagcct atgaggctgt tccgcttgac
     9061 cttggtgatc acgtgattgt catcatgaat accaacaagc gccgagagct agccgattca
     9121 aagtataatg aacgccgagc agagtgtgaa caagcccttg aggaattaaa tgcccttctg
     9181 gatattaaag cactggggga attagacgct cagcgctttg atgagtacag ctaccttatc
     9241 aaagatggta aacgtctcaa acgcgctcgc cacgctgttt tggaaaatca acgaacactc
     9301 caagcaagac aggcccttga agcaggagca ttggagcaat ttggtcgtct gatgaatgct
     9361 tctcatgtat ccttggagca tgattatgag gtcacaggcc ctgagctgga cacactggtc
     9421 cacaccgctt gggagcaaga aggggtccta ggggctcgca tgacaggagc aggctttgga
     9481 ggctgtggca ttgctatcgt ggctaaggat aaggtagata gctttatcga aacagttggc
     9541 aaggcctata ctaaggtcat tggctatgct ccagcctttt atctggctga gattgctcag
     9601 ggagcacgac tactttcaag gaaataagat atggcaagct taatagacac ctttgtaagg
     9661 aaggtgattg aacacagcga ctacacatca gaggacgcta tttatatccg caatcgggtt
     9721 ttagcattgg ttggtgagaa ccatgtctgg caagaaacct ccttaacagc cttaatagct
     9781 ctcaaagaag cattggttga gctagctgct gaaaatggca aaataggcag gcttcctgaa
     9841 gaaaaggact gcttaggagc tgaattaatg aacatgataa cccctattcc aagtgtggtt
     9901 aatcgtcgct tctgggatac ctatgcacaa tctcctcaac aggctatctc agatttttac
     9961 cagcttagtc agctaaatga ctacatcaaa acagcagcaa ttgccaaaaa catctccttt
    10021 acagtgcctt ctcaatatgg tgatatggct attaccatta acctatcaaa gcctgaaaag
    10081 gaccctaagg ccattgcagc cgctaagaag gctaaggcat cctcttatcc aaaatgccag
    10141 ctttgtatgg aaaacgaagg ttatcaagga cggattaacc acccagcccg agctaatcat
    10201 cgcattatcc gtatgagctt aggcaatgag gcttggggat tccagtattc accctacgct
    10261 tattttaatg agcacagtat tatttttaat actgagcatg tgccaatgac aatcagtaca
    10321 agcaccttta gacagctcct tgatattgtt gatatcctgc cagactattt tgtcggctct
    10381 aatgctgatc tgcctattgt tggcggctct attttgaccc acaaccatta tcaggccggt
    10441 cggcacgttt ttccgatgga aatcgcaaaa caagacaaac gctttacctt taaaggattt
    10501 ccagacatac aggctgccac tctcaactgg cctatgtcag ttatccgact gcgcagcagc
    10561 aacaaagatc agctagttca attagcagac acgattcgac tggcttggcg tcattattct
    10621 gacgacagtg ttgatatcgt cgcttatacc aaccaagagc ctcaccatac catcacacct
    10681 attgccagaa aaaaagaagg gcagtttgaa ttagacttgg ttctacgtga taaccatacc
    10741 tctgagcaat ttccagacgg tgtttaccac ccacatgccg atgtgcaaca cattaagaaa
    10801 gaaaacatcg gccttattga ggttatgggg ctagctattt taccaccgcg cctcaaagag
    10861 gaattggttg aggtcaaaaa atatatcctc aatcaagcca atcaaatcgc agactaccac
    10921 aaggactggg ctgatcagat cacattacga ccagatctct cagcgataac tgttgatgac
    10981 attatccaag aagaggtcgg ctctgtcttt gttcgtgtcc ttgaggacgc tggcgtctac
    11041 aaacgtgatc aagaaggtca agcagccttt atgcgttttc ttaagagcat tggcattgaa
    11101 gcaattgaag aataggagga aaaaatgact gttctagttt taggcggtgc aggctacatt
    11161 ggatcacata cagtggactg gctaatatca cagagagaag aaaaagtcat tgttgttgat
    11221 agcttggtga cagggcaccg taaagccgtt cacccagagg ctctgtttta caaaggagac
    11281 ttagcagaca aagcctttat gcgtcaagtc tttagggaca atccagacat agacactgtg
    11341 attcactttg ctgcctcttc cttggtcgca gaatcaatgg cagaccctct gaaatacttt
    11401 gacaataaca cagcaggtat gattaagctg cttgaggtca tgagagaagc caaggttaag
    11461 cgcattgtct tttcatcaac agcagccgtc tatggcattc caaaaacagt ccccatctta
    11521 gagtcagcgc ctaaatgccc aatcaatcct tatggccaaa gcaagcttat gatggaaacg
    11581 ataatgacct gggccgacaa agcctatggc atcacatttg tggcccttcg ctacttcaat
    11641 gttgccggag caaagccaga tggctccatc ggtgaagacc acgagccaga aacacattta
    11701 ttacccatta tcctacagac tgcacaggga gtgcgtgagc aggtgatgat ttttggtgat
    11761 gattatgaca caccagatgg tactaacgtt cgagattacg tccatcctat cgatttagct
    11821 gatgcacaca ttttagcgat ggcatacctg cgtcagggca aaccatcaca ggtctttaat
    11881 ctagggtctc aaacaggctt ttccaatcgt caactgcttg aagccgctcg tcgggtaaca
    11941 ggacaagcca taccagccaa aaaagctgca agacgtcccg gtgatccaga caccttaatt
    12001 gcgtcatcag aaaaagcacg caaggttctc aattggaagc caagctatga cgatattgac
    12061 aagataatcg catcagcctg ggcctggcat accaagcatc caaaaggata tgacgataaa
    12121 gcaagtggca gctagtccct caagacagct accacagcaa gtagtcagcc tcccttaatt
    12181 catacaccta tactaatagg agaaacaaac tgtgaacatt tatcaagaca tcattgaata
    12241 catcgatcaa gtgccagtca cccagctaag actgattaat actaacggtg ttgaggctca
    12301 cctattgaca ctaggagcca ctctacaggc ctttctagtg tcaaatgaaa agcagccaaa
    12361 aaatatcatt ttgggacatg accgaccaag tgactaccta aaaaatcctc tttgtgcagg
    12421 gcaaaccatt ggccgagtag caggtcgcat aaagagagga agctttcagc tagagcagca
    12481 aagggtttgt gttgacacca atgaaaatgg gcattgcctg catggaggct tcaagggctt
    12541 tcataagctt cattggcctt atgatacccg ccaaacagtt gattaccttg aagtaacctt
    12601 taaaagggat attttagaag cagatgacca tttcccaggt gacctgaccg taagcattac
    12661 ctaccgtcta gacaaccata atcgtttaag cattcacttt aaggctcata gcatgagagg
    12721 cactagccta ttcaatccaa ccaaccatgt ttattttaat ttagggcaaa cacaagactt
    12781 aaccaatcac aacctataca tcgcagcatc acataggatt gaaacagata atgagctaat
    12841 cccaacaggt caaaagctag cagttgacca gacggtctat gattttagat caataaagtc
    12901 cctctatcct gctattgtcg aaaataatgg ctttgatact gcctttgaaa ttgatcagca
    12961 ggctattgga acaaccaaac ctattgctgt cttacaagac agcgtcagcc atgaccaaat
    13021 cagcatctac tctgaccgaa acgcactcgt catttatacc atggacagta tccaagatgg
    13081 cttgtatttt ggaagagatc agggcaagga gggactggct cgtgagggga tcgctatgga
    13141 agcacaaacc ctgcctgatg ctattcacca caaccagttt ggtgacatta tcctcaaaga
    13201 aggaggcacc aaaagctaca ctatctgcct agcctatgag catctgccag attaacataa
    13261 gtacagccaa gctttaatga aataacaaga ccttgatttt tttgaattgc accccaaccg
    13321 ttagccaaaa actctaacaa gcgaggatca gttcattcat caaggtcttt tcctcttttt
    13381 atctataggc gttacaaagt agatatagga acatcatacc aaatatgtgg aatgctaaga
    13441 gcttatcatc acaaagcgaa tacatgttcc gactacatct atgcattagt aagtcttttt
    13501 cctaaacgaa gtgttgccag ctttatgaga tacttaaaag tataagagca gcctaatcat
    13561 ttttgacaaa gacaccaacc ttaagcataa acataggcat cagaaatttt ggtatatggg
    13621 ctattatgga gacacagctg gtaaaaatct aaaaacgata gccaaatata tttcaaatca
    13681 ctataggaag atagggtagc aaaccaactg acatcatttg agaccattga tccatttaca
    13741 ggccaaccaa ataagaaaaa gtaacctttt gattgaactc ccgctcggaa aagtggagcg
    13801 cgagtattca atgacctcgt tatcctcgac cgatgagagc agcttatagt cacagtataa
    13861 agaggctgga acagacaacc tcttttgatt gacaataagt gtttgatagc attgtatggg
    13921 attactttca catcattcag cacctgggtc gagctttgat gaccgccaga attgatagcc
    13981 attatgaagg gctttgagca gccatttctg ctttatcgaa ccataaaata tcattgatga
    14041 ctgctccaaa aggacagtca taaactgtct gatcagcgct tctagtcacg aacctttaag
    14101 caaaccttaa tactcaaaaa aggtaagtca gaaaatactt gatttctcag atgagctgtg
    14161 gaattaccac gacctttacc agctcttgct ctttcatttt caaaaagtgg gtaaccgagt
    14221 ttttcgggct gattgaagag ctttaagctt ggtcaatcat cacgttttaa ccgtcctcaa
    14281 aatctttttg aaatacaaac cctacatcac aaatgcctta ttccaatgct aaattggagc
    14341 ccactaacaa gactattaag gacatgaaag agcaagcctt tggatttagg aactttaaga
    14401 acttcaaagt caagattccc aatgctttaa acatcacaaa agaagagaca aaatttatct
    14461 cttctcgtgc ttagctatca gtcacccact gcagttgaca ttgagccaaa ttatagagcc
    14521 attttcgtag aaagcacaga aaaaacaccc atgaggtaaa ctcttgagtg ctttgaaacg
    14581 ttgatataat gcgatatatt aacgttttga ggcacggaga ctgcgtctcc tttgcagccg
    14641 tattcgtaag cgactaaagc cgcaacgact acgtcaattg cgtcgccagt tctttcaaaa
    14701 aagaaaatac cccatggtaa cccatgaagt attgttctgc tgtattgtag ctggttctta
    14761 acgttttgag aactgactag ctttacgagc tttcttaaga cctggttttg ggtgacaaaa
    14821 accaaatatc tgtaaaagct tatcaaatca agctttcaaa actcattttc attaaatata
    14881 agcactttta acccaatcct acaaataata gattaccatt agattaccaa aactcagttt
    14941 tcggagctta tgtagttgag aaaatctcgt atttactttg cttttatata tccactttat
    15001 actatcatcc cgtcataaca gagcatgatt aaa
//
LOCUS       DARYXW010000049        14600 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.049, whole genome shotgun sequence.
ACCESSION   DARYXW010000049 DARYXW010000000
VERSION     DARYXW010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14600
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.049"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            <1..255
                     /locus_tag="TV191_001234"
     CDS             <1..255
                     /locus_tag="TV191_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HEL1507750.1"
                     /translation="QFTRAGIIENLIFKGFVERDKKNLIATHKGISLVAIVADNFKSA
                     ETTAKWEMELSDIAQGKSSKEEFLEAIENEIKEAVSTYSK"
     gene            339..518
                     /locus_tag="TV191_001235"
     CDS             339..518
                     /locus_tag="TV191_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HEL1507751.1"
                     /translation="MKDTFIDTAKVMSKGQVTIPKRIRELLNLENGDYVTFVVNKDRV
                     EIQNSNVFIEENIKK"
     gene            537..1964
                     /locus_tag="TV191_001236"
     CDS             537..1964
                     /locus_tag="TV191_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA binding domain-containing protein"
                     /protein_id="HEL1507752.1"
                     /translation="MTIDEIKKLIQAGEKIDVEFKESKNALTKDVFDTVCSFNNRNGG
                     HILLGANDKREIVGVSEDKVDKVIKEFTTAINNPQKMYPPLYLLPETFEIEGKQVIYI
                     RVPEGYQVCRHNGRIWDRSYEGDINITDHSELVYKLYARKQGSYFVNKVYPNLDIDFL
                     DASVIDKAKKMAVFRNKNHVWENMSNEELLRSANLILTDPETKREGITLAAILLFGKD
                     NSIMSVLPQHKTDAIFRVENKDRYDDRDVVITNLIDSYDRLIEFGQKHLNDLFVLDGI
                     VNVNARDRILREIVSNTLAHRDYSSGFPAKMIIDDERITVENSNLAHGMGALDLQKFE
                     PFPKNPAISKVFREIGLADELGSGMRNTYKYTQLYSGQNPLFEEGDIFRTIIPLKKIA
                     TQKVGGDNVAHDVAQGVAHDVAHDKIALAEFIKEKVRSNDRITRKAIADEAGVSVKTI
                     ERAIKEIDNLKYVGSGNSGHWELNE"
     gene            2136..8966
                     /locus_tag="TV191_001237"
                     /pseudo
     CDS             2136..8966
                     /locus_tag="TV191_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365295.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            9476..11241
                     /locus_tag="TV191_001238"
                     /pseudo
     CDS             9476..11241
                     /locus_tag="TV191_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678622.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="reverse transcriptase"
     gene            11349..13259
                     /locus_tag="TV191_001239"
                     /pseudo
     CDS             11349..13259
                     /locus_tag="TV191_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989360.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
     gene            13303..13962
                     /locus_tag="TV191_001240"
     CDS             13303..13962
                     /locus_tag="TV191_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006627214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1507753.1"
                     /translation="MDYKTMRNQIEDMANDNHKDFVKAIISVEKGINDESALDKLYDA
                     YMDNDSLNLLHEEFDYMIEDLREQGQIKDLPYVQEEKDNLINIVGNIVGKVDVAEREN
                     KNGEAFKVANFSVVSKDDEGNKVYHNCSAYGEKSDIPKDFKQGDFVKLFGQIRTSIDD
                     NGKEHSNVRILSSKLLKAKEQMKGQEEKKESVLGAIKKYQSEDKEKPKEKRDASKEAE
                     R"
     gene            14112..14327
                     /locus_tag="TV191_001241"
     CDS             14112..14327
                     /locus_tag="TV191_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1507754.1"
                     /translation="MSKISYKKLFKKMIDLDMKNSELMEKAEVSRSTFYKMKNSENIT
                     TDVIVRICDSLNCGVNEIMELVDDENN"
     gene            14311..>14600
                     /locus_tag="TV191_001242"
     CDS             14311..>14600
                     /locus_tag="TV191_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HEL1507755.1"
                     /translation="MMKIIDYVIESTNKYIKQMPKEIRKKNGQFFTSKETALFMASLF
                     DLSSFSKEISILDPGAGSGILTAALIQRIIDTDKIEAIKITCYETNDDILEL"
BASE COUNT         5372 a         2104 c         3264 g         3860 t
ORIGIN      
        1 cagttcacaa gggcagggat tattgaaaac ttaatcttta agggatttgt agaaagagat
       61 aagaaaaacc ttatagccac acataaagga ataagccttg tagcgattgt agctgataac
      121 tttaagtcgg cagaaactac cgcaaaatgg gaaatggaat tatccgatat tgctcaaggg
      181 aaatcttcaa aggaagaatt tttagaagcg attgaaaatg agataaaaga agcggtttca
      241 acttatagta agtaagatga cactaatttc agagtagaaa aaatatctta aaagtgctat
      301 aatcttttgt aggaaaagta gggcgaaagg gattagtcat gaaagataca tttatagata
      361 ctgctaaagt tatgtcaaaa ggacaggtta ctattccaaa gaggattagg gaacttttga
      421 atttagaaaa tggagactat gttacttttg tagttaataa agatagagtt gaaattcaaa
      481 attccaatgt ttttatcgaa gaaaacatta agaaataaag gtggtgaaat aaacagatga
      541 cgatagatga aattaagaag ttaattcaag ccggagaaaa aatagatgtc gaatttaaag
      601 aatccaagaa cgctttaacc aaagatgtct ttgatacagt atgctctttc aacaatagaa
      661 atggcggaca tattttactt ggtgcaaatg ataaaagaga gatcgttggt gttagtgaag
      721 ataaagtaga taaagtgatt aaggaattta ctacggcaat caacaatccg caaaagatgt
      781 atccaccact ttatttgctg ccggaaactt ttgaaattga ggggaaacaa gttatttata
      841 taagagttcc tgaaggttat caggtatgca gacataacgg aagaatttgg gataggtctt
      901 atgaagggga catcaatatc acagatcatt cagagcttgt atataagcta tatgcaagaa
      961 aacaaggaag ctattttgtt aataaggtat atccgaatct tgatattgat tttcttgatg
     1021 cttctgtcat tgataaagct aagaaaatgg ctgttttccg aaataaaaat catgtttggg
     1081 aaaatatgag taatgaggag cttcttagaa gtgccaattt gatactgaca gatccggaaa
     1141 caaagcgtga aggaatcaca ttagctgcta ttttgttatt tggaaaagat aactctatta
     1201 tgtccgttct tccgcaacac aaaactgatg ctatattcag ggttgaaaat aaggatagat
     1261 atgatgatag agatgttgtc ataacaaatc tgattgacag ctatgacaga ctgatagaat
     1321 ttggacaaaa gcacttgaat gatttatttg tcttggacgg aattgtcaat gtcaatgcaa
     1381 gagacaggat actcagagaa atagtttcca atacgctggc tcatagagat tattcaagtg
     1441 gttttcctgc aaagatgatt attgacgatg agaggattac agttgaaaac agcaacttgg
     1501 ctcatgggat gggagcttta gatttacaga agtttgagcc atttcctaaa aatcctgcta
     1561 tatctaaagt ttttagagaa ataggtcttg cggatgaact tggttcagga atgcgaaata
     1621 cctacaaata cacacagctt tattcaggac aaaacccgct atttgaggag ggagatatat
     1681 tcagaacgat tattcctcta aagaagatag cgacacaaaa ggttggaggc gacaatgtcg
     1741 ctcacgatgt cgctcagggt gtcgctcacg atgtcgctca cgataagata gctctcgcag
     1801 agtttattaa agaaaaagtg agaagcaatg ataggattac aagaaaggct attgcagatg
     1861 aagctggagt tagcgtaaag actatcgaaa gagctataaa ggaaatagat aatctgaagt
     1921 atgtaggaag tggtaatagc ggacactggg aactgaatga ataaaattaa gttgcaaaac
     1981 aaagattttt ataaataaga gggtgctatg aataccataa aatgaggatt tgtagtagga
     2041 aatttaagtt gcagcaagtt gcaatacaca gaatcaaaag gtgattagag taaaatctaa
     2101 ccgccttttt tgtttggaaa aagaaggagg taaaaatgcg aataaatgat tttcataaca
     2161 ttttggagct tgtaaaacaa aatattttgc aaagtgaagc agaatacctg aagctcctaa
     2221 aggttgtcgg aaacaatcaa agatatgact ttagaagtca gttaagtatt tatgatagaa
     2281 attctgaagc gacagcctgt gccaagttcg actattggag ggaacgcttt aaccgtactg
     2341 ttatgagagg acaaaaaggt atccccattt tagaggacta cggcacatac aaaaaagtgg
     2401 catatatctt tgatataagt cagacggttt caagaaatag ggatgtcaat gaggtcaatc
     2461 tttggagatt tgataaagaa gctcataggg atgtcttaaa ggaaatgata aaaaacgagg
     2521 gctatgagga aagtgaaagc accttagaaa atatcttttc tttaagtaga ctctacggtg
     2581 atgaaaagat agacagcctt atgaatgagc ttagaatagc tgatgaggat agaatatctt
     2641 ttaccaagtt tgtgagggac tcagtgagtt atgcagtagc ttcaagattt aatgtagact
     2701 atcctatgga taatgagctt ctaaaggaaa actttgcaat gcttgatagc atttccctta
     2761 tgagtcttgg tgaaatcgta tcggatatta gtggaaagat tattgatgaa accattcaaa
     2821 aaagcaaaga gcttgagctt caaaaagaag ttttaagagg aaaagaagca ggatataata
     2881 ggattaaaga aaaaattgag aaaggagata atgatgtact tcgacgagat gatcaggaaa
     2941 gaaatgaaaa tgagcgagtt ctccgaaatg gagagtacgg acgagataat agagaaaatc
     3001 agggagaata cactaaacag cttggaggaa cagacggact tcataaggga gtatccgaat
     3061 ccgacctacg cagtaatgag gctggattac ctttcagaga gcgaggagca gagccacttc
     3121 gagatgttag tggatctata caaggagagg aagctaacag gacacctgat ggatattcag
     3181 aaacaggcga tagactttat gaggacagag aagccgaaat tgatggtagc ttggaagata
     3241 gaggacgaga acgatccgca gtatggggcg atgatttcag ctctgaagga aatgacaatc
     3301 aaggaagtat taaaaattta aaagataata ctgaggtaga gataagagaa gctgaaaagg
     3361 cttctttttc tttacccgaa aattcatatg gacagatgag acttaccatt ccattaactc
     3421 agagggatat agatactgtc cttattaacg gaggaaatca cgatggaagt agacttcctg
     3481 ttatcgctga gttttctaaa ggaaaaagta atgaagaatt aggagaatac ctaaaagata
     3541 tatttagagg cggtaatgga ttttacattg atgaaagaga agtatcttcc tggtattcgg
     3601 ataaaggcat tcatttagcc tacgggacat ctgcaagaga agatactacg caaattttaa
     3661 gctggagcga tgctgcaaag aggataaatg agcttcttga taatggtgag tttgctacaa
     3721 atgtagagat ttctgaggct cctgattatg aaagagataa gatttcagag tccttatggt
     3781 atctaatgca tgatttaagc gaagaaggac aaggatattt tgaactattg aaaacaagtg
     3841 gaagaggctt tccggaagaa acaaaaagat tgtctgaagc attaaaaaat cccgactacc
     3901 taaaggaaac gatcaaagaa tacagcaggt ttttagaagg atacaaagaa aacagaaatg
     3961 tattaaggtt tcactatcac aaggtagata gcctttgtca gaggttacag gaacttgagc
     4021 tgtcacgaaa ggaatatagt accaatctaa cagagcttcc gaaggtaaag tccttcatta
     4081 cagaagatga agtccttgaa agtctttcaa gaggaagtgg cgtcgataga ggaaaagagc
     4141 gaattacaaa gtttttcaaa gaaaatcata ccttgcagga aaaagctaat ttcctaaaag
     4201 acgaatatgg cataggtggt agaagtcatg cagtatcggg ggcaatggga agtgatgaat
     4261 ggcatgatgc aaaggggctt aaattacaga agaataattg taatgatgtt tttcttactt
     4321 ggtcaagtgt ggcaaagcgt atagaggagc tgctttctaa aaatctgtat gaagaaaaga
     4381 aaatagaaag taagtcagag gtagaagaat caaaagagct acaatattat tctaaagata
     4441 atcctgaaaa cttaatgact gatgaaatgc ttgaaagagt gcctgagctt tacgcacagg
     4501 aagatgtagc tttagcggat aaagaggttc atgcagcata tattattcct ttccgttcta
     4561 actggacttg gtatatgacg gaatatgata gggaaagcgg tgatgccttt ggacttgtgt
     4621 taggatttga acctgaatgg ggatatttca atcttgaaga attgaaagaa ttaaatgctc
     4681 aaaggcttat tttagaggat tttccaaaga cttttagaga gcttaaagat acagaacttg
     4741 caaagcagat ggatgaacag gaacttcaat cagtctttaa cggagaactt agctttgaag
     4801 ataaagaaga acttgaaata tctgaagaag tggaagaaag agtagctgca acacctgttc
     4861 aggaaacact atttgattat ctgaaggaga aggaagaagt agagcttaac gaagaaaaga
     4921 aaagtatttc agatgaattt gcagttaaag agggcgatac cgtctatttt aatcatgaag
     4981 aatatactgt aagggaaatt gctgaaaata aaatcacaga aagatatgac ttatggcttg
     5041 atccgggaag aagtggaaac catcaaatcc ctattgtagc ctttacagat aatgaagatt
     5101 tattaagaca agtaagccct gaaagacctg cgtttatcgt tggagatgaa attaaataca
     5161 aggataaaga ctataccatc acacgctttg acgatatggg aaataatcta aagacggtaa
     5221 cggttaagga taataccgaa tatcttggcg gtatgataac aggctcagat gtaattcctt
     5281 atcgtcttga aagcgatctt gagagggtat ttgaaaatct gacatataaa aagcctgaaa
     5341 ctattgctaa agaaagtgaa ataaagaaag cagaagctca taacttcaag attacggaag
     5401 aaacattacc tgacaagtta tctccaagtg aaaggctaaa taataacctt gaagccatct
     5461 ctatgctgag tcgcatcgaa agtggacaaa gagagtttga cagtacagct caggaagttt
     5521 tagcaaggta tgtaggctgg ggtggacttg ctgatgtatt cgatgaagaa aaaggcggac
     5581 agtggaaaga agcgaggagc tttctaaagg aaaacttatc tcaggcagaa tatgaagctg
     5641 caagagaatc taccctaacg agcttttaca caccgaaaac tgttattgac ggcgtatata
     5701 agacactttc cgatatggga tttaagagcg gaaatatcct tgagccatca atgggcatcg
     5761 gaaactttat aggaaatctt cctgatgaaa tgaacaagtc aaagttttat ggtgtagagc
     5821 ttgacagtat aagcggtagg attggaaaac ttttataccc tgaaagtgat atacagatta
     5881 aaggacttga agaaacttct ttttccaata acttttttga tgttgcaatc ggcaatgttc
     5941 cctttggaga atacaaagta aatgacaggg aatacaatcg taataacttc cttattcatg
     6001 actatttctt tgccaagtcc attgataagg ttagaaacgg cggggttatc gcctttatta
     6061 catcaagtgg aacaatggat aaaaaggatg aaagtgtaag acgctatctt gcagcaagag
     6121 cagagttttt aggagctatc agacttccta atgacacctt taagggtact gccggcacag
     6181 aagtaacctc agatattatc ttcttaaaga aaagagatag cgtattagag cgtgatgaag
     6241 attggataca ccttgcggaa gatgaaaacg gtcttgtata taacaaatac tttgttgatc
     6301 atcctgaaca ggtacttggc tcaatgcgtg aagtaagcgg aagatttgga aaaactctaa
     6361 cttgtgaacc gatatcttat ttaggcacag agctaaatat ggcttcatta aaggatcgta
     6421 tcgagattgc aggagaaaga atttcaaaag atgccaagta tgaagaaata gagcttttag
     6481 atgatgaaat cacttcaatc cctgcaacgg atgatgttaa gaacttttcc tataccatta
     6541 ttgatgatga agtctattac agagaaaact cactgtttat caaaaaggaa gtaaccgata
     6601 aaaacaaaga aaaaatcaag gattatcttg agctgaatgc tgccttaaaa aatgtgattt
     6661 acaagcagaa agaaggtttt agtgaggaag aaatcaaggc ttcacaggaa aaactaaatg
     6721 aagtctatga ccgtttttct aataagcatg gctttgtaaa taatttaagc aatacaagag
     6781 ctttaaaaga ggatagcaac ttcccgcttg tttcctccat tgaaatcctt gatgaagaaa
     6841 actttaaggc aaagggagat attttctcca aaagaactat tacaaaggct aaagtcatag
     6901 atcatgtgga tacttcttta gaagcccttg tcttatcggt atctgaaaaa ggatatgtgg
     6961 actttgacta tatggaaggt cttacaggaa aagacagacc gactttgatt gaggagcttc
     7021 gaggggaaat ctacttaaat attagggaag aacaaaactt ttatagacct ctatccttta
     7081 accccgaaga tggagatttg ccttttgcct gtgccaatgg cagtaattcc tacaaatacg
     7141 gctatgtaac aaaggatgaa tatttaagtg ggaatatcag ggacaagatt gccatagtag
     7201 atagctatct atcaaagctc agacagacgg aaagagagtt acctcatctt ggctatgcag
     7261 aagatggtaa agaaaaagag ctgattagct atgagatgaa tcgtttggaa taccaaaagg
     7321 ctgagcttac aaaagttcta ccaaaggagc ttgaagcaag tgagataagt gttcgtcttg
     7381 gtgcgacttg gataccgatt aaagatattg aaaaatttat ttttgaaacg ctgaaaactc
     7441 cgggatatgc aagatgggat attaaggtta agttttcaaa cctgacaagt gagtggaata
     7501 tagaaggtaa aagtagggat agaggaaatg acctcgctga aatgacttac ggtacatcaa
     7561 gggtaaatgc ctataagctg attgaagatg ccttaaacct gaaagaaaca aaggtatttg
     7621 accagattgt aaatccggac ggctctaaaa cttctgtact aaataaaaaa gaaaccatgc
     7681 ttgcagggca aaagcaggaa ctactaaaag aagaatttaa gaactggata tttaatgatc
     7741 aggagagaag aaaccgtctt gtaaaactgt ataatgagcg ttttaactct atccgaaaca
     7801 gagaatatga cggaagtaat ctttcctttg agggaatgaa tactaaaata gatttaagac
     7861 ctcatcagag aaatgccata gcaagaagtc tttatggagg caacaccctg cttgctcatg
     7921 tggtgggcag tggaaagacc tttgaaatgg tggcttccgc aatggaaagt aaaagacttg
     7981 gaatgtgtag taagtccttg tttgttgtac ccaatcactt aacaggacaa atcggtcgtg
     8041 agtttatgca gctatatccg tcggcaaata tcatggtggc agataagaaa gattttgagc
     8101 cgaagaaccg taagcgtttt atcggtcgaa ttgccacagg agaatacgat gccgttgtta
     8161 tcgggcatac gcagtttgaa aaaattccta tgtctaagga atatcaggag aagcatatcc
     8221 aagatcagat tgatgaaatc gtaaactatg tagaagaata caagcatgac agaaatcaga
     8281 actttacagt aaaacagctt gaaaagacaa agaaaaaact ggaaacaagg cttgagaaat
     8341 taaatgacga ttttaagaaa gatgatgtca ttacctttga ggaattagga gttgataagc
     8401 tctttgttga tgaagcacac aactacaaaa atctctatct ttatacaaaa atgcgtaatg
     8461 ttgcaggaat cggtcaaagt gaagccttta agtcctccga tatgtttatg aagtgtcgct
     8521 atatggatga aatgacaaac ggaaaaggca ttgtctttgc aacgggaacg cctgtatcaa
     8581 actccatgac tgagctttac actatgcagc gttatcttca gtatgagagc ttaaagaaaa
     8641 ataatctgga gcattttgat agctgggctt ctacttttgg ggaaacgcag tctgcttttg
     8701 agctttctcc ggagggaaca ggatacagag taaagacaag attttccaag ttctataact
     8761 tgcctgaact aatgtctatg tttaaggaag tcgctgacat tcaaacagcg gatatgttaa
     8821 atcttccaac acctgaggca cattatgaag taattaagac cttgccaagt gaggagcaaa
     8881 aggaaattct aaagagcctt tctgaaagag cagatgatgt gagaaatagg gtggtagagc
     8941 ctgacaaaga taatatgcta aaaattgtgc gctgttaagc gtaaaaatgt atctccctca
     9001 cagagggata ttattgaaag taaataatag gaacaactaa ctaacctagc ggggaaaccc
     9061 aaaggggaca atagcatgtt agtaaagcgg ataaggagtg agttacaacg ctttgatgtg
     9121 ccgcaagttc cgtaacctat ggttaaggct aaactgcttg aacctcaatt ctgactaggt
     9181 gcaaagcatc gcccatcgga aagtaactga gaccgatgtt actgtatatt cgttgttgtg
     9241 attttggacg aataactttc tacagtaaaa gagcatacga taagtatgaa taaaggaatg
     9301 agtgaggaac ctaagggtta ctagaacgta catttttaac gaatagcagg attgcctaag
     9361 aggggggacc cttatggtaa cggagtcacc gtagtagtcc gagcaaggga aatccttgta
     9421 catggcgaag ggtgacaggt aatttcgatt agttagaaag gattaggtgc gtgggatgcg
     9481 tacagccaaa actattttaa cggtcattca tgaacgtgga aaacaagata aaccactcga
     9541 aagggtttat aagttactat ttaatcgtga actctatctg atagcctatg caaagttata
     9601 cccgaataat ggagcaatga caaagggtgt tacagaggaa acgattgatg gaatgtctat
     9661 tcaaaaaata gatatgatta ttgaacaatt aagacaagaa acctattact ggagaccagc
     9721 taggagagag tacattccta aaaagaatgg aaaacaccgt cctttgggaa taccagtatg
     9781 gagtgataaa cttcttcagg aagtgattcg catgatatta gaagcctatt atgagccaca
     9841 atttagtgaa cattctcatg gttttagacc aaaaagaggg tgtcatacag ctttacaaga
     9901 aattcagact tggaaaggga cacgttggtt catagaagga gatatctcta gttattttga
     9961 cacgattgac cacgatgtat taatcactat gttgtctaga caaattcagg atggtcggtt
    10021 tattaggctt atcaaaaata tgcttgaggc aggatatctt gatgattgga agtttcacaa
    10081 gactattagt ggaacaccgc aaggtggagt tattagtcct ttattagcta atatctattt
    10141 acatcaattt gataagtggg tcggtgaaga gctgatacct caatatacaa gaggtaaaaa
    10201 gcagaaagca aactcagcct ataatcgttt gagtagaaga attaaatgct atcaggataa
    10261 aggagattat aaaaaagctc atcagttaat tgttgagaga agaaatctcc cttcagttga
    10321 tacttatgat accagctatc ggagattaag atatgttcgg tatgcggatg actttattct
    10381 aggctttaca ggttcaaaag ctgaggcaaa ggctataaag aagcaaattg gagacttttt
    10441 aaatactaag ttatctttgg aactttctca agaaaagact ttgattaccc atgcgactgg
    10501 agaatcagct aaatttctgg gatatgagat aaaagcacaa cgtgtcaatg attatattga
    10561 taacaaaggg agacagagtg ccaatggtgt tatcgcatta tttgtacctg catcagttat
    10621 tgaaagcaaa tgccgccaat acatgaaaaa tggtaaagct attcatcgta ataacttatt
    10681 gcatgatgat gactttagta tcgttcaaac ttaccaacaa gaatatagag ggctagttca
    10741 atattatata ttggcacaaa atttgtcatg gttctcaaaa gtctattggt atatggaaac
    10801 atcactcctt aaaacattag catttaaaca tgagtcatcc attaataaaa tgttagctaa
    10861 atataagact accacaacta gcacgaatgg ccgaacggtg ccgtgtttac aggtagttgt
    10921 gtctcgagaa gataaacctc ctctagttgc aacgtggggt ggcataaaaa gaaagctgta
    10981 atagaagatg ctccgtatca agtttatggt ggtcgaacag agcttatcaa gcgattactc
    11041 gcaaataagt gtgagctatg tggaagtgag gagaacatag aggtacatca tatcagaaaa
    11101 ttagcagact tgaacaaaca caatgggaaa ttagttccaa agtggaaaga aatcatgtca
    11161 gcaagacgtc gaaaaatgct agtgacttgt cgggattgtc accatgcaat acataatggt
    11221 tcaataaata cacgtttatg aaatgaaatt actggagagc cggatgatgc gaaagtatca
    11281 tgtccggttc ggtgggggga taatggaaaa ggggtcgcaa tgactacctc gctagtatcc
    11341 taccctacac taatgatggt aaaaaacttg ccttagatca gcgtttaatt aatcctctgc
    11401 tacctgacaa tcctgacagt aaggtcaatg tctgtgtgaa aaatgtcttt agtatatggg
    11461 ataagacaaa agaagataag tcaacacagc tactattttc tgatatgtct acaccaaaag
    11521 gcgatggaga atttaacatc tatgatgata ttagagaaaa acttgtagca atgggaatac
    11581 caaaagaaga aatcgccttt atccacgaag cgaattccga taaacaaaag gacgaactct
    11641 ttgcaaaggt gcgtaaagga gatgtgagga tattacttgg ttctactcag aaaatgggag
    11701 ccggcacgaa tgtacaaaac aaactgattg cccttcatga tttggatgtt ccttggcgtc
    11761 ctgccgattt agagcagcgt gcgggcagaa ttgtaagaca gggcaatgaa aacaaggaag
    11821 taaatatcta tcgttatgtt acggagaaca cctttgatgc gtatttgtgg cagacaatag
    11881 agaataagca gaagttcatt tctcagatta tgacaagtaa aacacctgtc agagtggcag
    11941 aagatgtgga tgaaagttca cttaactatg cagaaattaa agcccttgcc acaggtgatc
    12001 cgaagattaa agaaaagatg gatttggata atgaggttac gaaacttaaa atgcttgaag
    12061 caaactataa gtccaaccgt tacagattag aggataaagt ggcgaaaaac tatcctgaag
    12121 aaatcgcaag aactgaaaag ctcatagaag ctgtcaagaa agatatatct gatgtagagc
    12181 ctaaagcgga cggagaggaa aagtttactt ctattactat cgcaggagca aagattaccg
    12241 ataagaaatt agcaggagaa agattgcttg aagctatttc aaaggttaaa atcaatgaaa
    12301 gtaaggtaat cggtaagtac agaaatatgg acttggaagc aagttataac ttctttacta
    12361 attctcataa tttcagctta aacggtgttg caaagcattc aggagagctt ggcacaagtg
    12421 ctgacggtaa tattacaaga cttgataacg ctcttgagaa aatgcctgag aaattaaaga
    12481 ggcttgaaga aaagctcata agcaccaaag agcagcttga aaatgccaaa gaggaattaa
    12541 aaaagccgtt tgaaaaagct gatgaattaa agagtaaggt gcttcgcttg gctgaactaa
    12601 ataagctact tgatatgggt gatgtggaag aaaagagaaa tgataatccc cttgtagaag
    12661 atgttaaaag ggcaattatt gatttctgta acagagaata tgaagaaaat catagctacg
    12721 atgagtttga tgctctatat cctgacttaa agcatatagg aattgcctat accaacacgc
    12781 cggatgaaag acacagcatt caatatgagc ttaatttaga ggataagata tggacacagt
    12841 atattgatga tatatctata aaaactgaga gctttgacta tgagaacaaa ggagagaatg
    12901 aaactctaag aaatatgaaa aatgagattg agctatcctc ttttgaagat ctggtttatg
    12961 tggattcaga agatttgaaa gcagcaacgg gacttgatat tgatgacgaa ggtaacttct
    13021 atgatccgct ttctaaagac cttgataatg acggaattac tgaccgttac gataatgact
    13081 ttaaggacag cgactatttt gaatcaacat atgatgtgga ggataatttt catagcaaag
    13141 aagaaagttc acaaaaatca gaggataagc catctatttt aggacagata agagcctatc
    13201 aggaagaaag taaaacagaa gaaaaacaaa ctacaaaaga acaggaattt ttaagataag
    13261 gggagggtaa cctccctttt actatgaaag gagataaaaa acatggatta caaaacaatg
    13321 agaaatcaaa tagaagatat ggcaaatgat aaccacaagg actttgtaaa agcgattata
    13381 agcgtggaga aaggtatcaa tgatgaaagt gctttggaca agctctatga cgcttatatg
    13441 gacaatgaca gtctgaattt actgcatgag gaatttgact acatgattga agatttacga
    13501 gaacaggggc aaataaaaga cctgccctat gttcaggaag agaaagataa tcttatcaat
    13561 atcgttggaa atattgtagg aaaggttgat gtagctgaaa gagaaaacaa gaatggagaa
    13621 gcctttaagg tggcaaattt ctctgttgta tctaaagatg atgagggaaa taaggtttat
    13681 cataattgct ccgcttatgg agaaaagagt gatattccaa aagactttaa gcagggagat
    13741 tttgtaaagc tctttggaca aatcagaact tccattgatg ataatggcaa ggagcatagc
    13801 aatgtaagga tactttcttc aaagctctta aaggcaaagg aacaaatgaa aggacaagaa
    13861 gaaaagaaag aatctgttct tggagctatc aagaaatatc agtctgaaga taaggaaaaa
    13921 ccaaaagaaa agagagacgc aagcaaagaa gctgagagat aaatatatgg tcggtgtggt
    13981 cttaggactg caccgactct tttttgtcta tctaaatgtc gtgtgtttgt gtaaaaggaa
    14041 gtttgtagtg aaaaaagtga ataaatatga tataatgata aaaacaaaat catatgcatg
    14101 ggaggacaat cgtgtcgaaa ataagttata aaaagctatt taaaaaaatg atagatttag
    14161 atatgaaaaa ttctgagcta atggaaaaag cagaagttag ccggagtact ttttataaaa
    14221 tgaagaacag tgagaatatt actactgatg tgattgtcag aatatgtgat agtttgaact
    14281 gtggtgtaaa tgaaattatg gagttggtgg atgatgaaaa taattgatta tgtaattgaa
    14341 tctacaaata aatatattaa acagatgcca aaagaaattc gcaagaaaaa tgggcaattt
    14401 ttcacaagta aagaaacagc tcttttcatg gcatcattat ttgatttatc atcattttca
    14461 aaagaaattt ctatactcga tccgggagcg ggttcaggaa tacttacggc agctcttatt
    14521 caaagaatta ttgatactga taagattgaa gccataaaaa ttacttgtta tgaaaccaat
    14581 gatgatattt tagagctgtt
//
LOCUS       DARYXW010000050        14364 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.050, whole genome shotgun sequence.
ACCESSION   DARYXW010000050 DARYXW010000000
VERSION     DARYXW010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14364
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.050"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            451..741
                     /locus_tag="TV191_001243"
     CDS             451..741
                     /locus_tag="TV191_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009853345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HEL1507756.1"
                     /translation="MATLERHHKMLLLSMALGAASWLALGLISLPNLAGALGISTANA
                     NTTVNLLSAYSTVSSVVAIVGAVTGVGSIGAGIAATVLYLIKQKGKAAAALW"
     gene            755..1894
                     /locus_tag="TV191_001244"
     CDS             755..1894
                     /locus_tag="TV191_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507757.1"
                     /translation="MKHVFKYHKGDILGYLNIVGFTLLFYGSVIGMIMFRDYLTYDGA
                     GSLISTFILVSGTYHSVKSTFPYEGKRHPTFILTPYYLFKHLLLSVTKVYAFQIRVVT
                     IGIICLAIAFPEQLVWIALSVLAVFIYWLSLPLVAIFRVAGRLLNLLMIYGMYLNQEL
                     LVIACLCLNVVILVLSVTINVHYPYQWLAVRARKEEKTITLLKLVINTITDHLALMVL
                     FSIFCIAVTYFTQRLLLSFDYSSFSIPVFFLSASTYIALLEVMVGKNIKELELDRGLA
                     VLQFLNRDISVYKAYRNSQFLLSAHILAVIHTGCAIGLLPFLLNGQAALFLSNLVMIP
                     FIYFISFCYFVKSLKIVAGDLSVFRWVILVLYFILVVIAMVGSRL"
     gene            1891..2373
                     /locus_tag="TV191_001245"
     CDS             1891..2373
                     /locus_tag="TV191_001245"
                     /inference="COORDINATES: protein motif:HMM:NF014052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HEL1507758.1"
                     /translation="MIMRKFLRYYISFIIFSIAIGILIGLLITSDTVILSKPERGWDF
                     TLEVLKNNSNNFLSYIFLFFLSPALQLIDLVSVVIQITLGMRKSGFLITALGLFPHGL
                     LEIPNFLFYQGLSQYMLWTVLTEKSMTSFLERERRYVRYYLISYYVLLIAGIMEGLLG
                     "
     gene            2370..2957
                     /locus_tag="TV191_001246"
     CDS             2370..2957
                     /locus_tag="TV191_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1507759.1"
                     /translation="MKIVNESKSFSNRKILNHISFDFSKGLYKVEGNNGSGKTTFLRL
                     LAGLERFDSGHRLQHKGDILYLDTNAIGVVPLTIEDNLTLLWKTFNASPDEETLSVIN
                     QFFGERLLDHYLTASVGTKAKVGLSLLFVKDWDYIFIDEALSTLDGFSLDMVAGRLLA
                     LKEKATVFYVSHNLSHQQLLSESQVIYLNGKGEIY"
     gene            2954..3436
                     /locus_tag="TV191_001247"
     CDS             2954..3436
                     /locus_tag="TV191_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507760.1"
                     /translation="MKGNPFNRNLSWLIAYVLLLSCYVFILVDGGFLKNSVQELEVLL
                     GQTSLAIKLFLMVISIAFSIISLLVEYFLSKFLVLLFIEAGIVSLNDVLTAKSVTLVI
                     HLSALLLKLSPSPLFQFVVNALGIVIMYGLSIKRQGNRTTALLFCLPFTLDILATLLL
                     "
     gene            3461..3976
                     /locus_tag="TV191_001248"
     CDS             3461..3976
                     /locus_tag="TV191_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507761.1"
                     /translation="MKKILYLSVLLGTSILATLIKIYNTFFAKLKASSGHSTGNIEID
                     ALLSESRLVLERQHAFTTNGINKLFVMMMSLMLLLALYYLIKKDLKAVYSYLLYLVLT
                     LVHAIYSFFSLSPLAKLYSDDMLGATIQTGEKAKLIFSVVLFLLYLLIVVANNRVKSS
                     VEPASSIGIDV"
     gene            4610..6244
                     /locus_tag="TV191_001249"
     CDS             4610..6244
                     /locus_tag="TV191_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507762.1"
                     /translation="MTRFFQKKQAKSLAIGFVSLFAVLIGYGAFHYSKASRINAYLQA
                     RSSGSGQVLENIKEYLVWADTNEQLTNDQARYTSFKRYSKAELVSKRQQLQTATAADD
                     MYVKSVGRKFLIFPDYRIAVKPVALTIKTNVPNVDILLNHKKIAVSQSEDFSTTIERL
                     PAADYKASINGYYKDRKIKVSKAYDGKNHTLDLRVTFKTFTVTSNVRDGELYIDGERV
                     ETLKAGQLQLEEYPVTEIAKAYIKKTFPDGELTSSKHSLAPVAEGSQLEINIDHLLTE
                     EQAGQVLVAAFDQLLTYLNQGQDPAGLSTVFEQGANNAFYKGLKDSIKAKFQTDTRKA
                     SRLSIPSILLSKLTQIGKQSYLVDFTAVYDFVYDKETDPEKGTSGNVRQDLTGKLTLK
                     KSGDSYLVSQSGPKNITVASEKNQVKPSIFPEGLVGTWIGHRSDMTFTMILAKDGSIT
                     TTIGNKNGNGSQTTKSAKITKVEEKGDGLFLYTVAPDADIAALVPGGGLGGVNVKYAF
                     GVKWSGDVATIVVWQTANNAAFDYSKPMLGPDMKKQ"
     gene            complement(6385..7278)
                     /locus_tag="TV191_001250"
     CDS             complement(6385..7278)
                     /locus_tag="TV191_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEL1507763.1"
                     /translation="MTTANKPEMGFQISFINPYQATTVKELLEDRLLIPRKIRHFLRI
                     KKHVWVNDELINWQSPVKQGDHIKLQFDQEDYPDKGILMGKPGLVDCLYQDEHLIIVN
                     KPEGMKTHGNEPTELALLNHVSAYTGKTCYVVHRLDMETSGAILFAKNPFILPILNRL
                     LEHRDIKRDYWALIEGQLEQQTVTYRDPIGRHRHDRRKRVVDSKHGQEAITHLALLQA
                     FDQTCLVNCRLETGRTHQIRVHLAHHKHPLIGDPLYSRQKAERLMLHAHQLTLRHPLA
                     QEMIRVTAPSKSFKEGLQQLN"
     gene            complement(7262..7453)
                     /locus_tag="TV191_001251"
     CDS             complement(7262..7453)
                     /locus_tag="TV191_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507764.1"
                     /translation="MNKFQAFKETLSAESLKAVYDETRLEVASDEREGTEAFSVTLAT
                     QMAINLIEKYHDWLNDNSK"
     gene            7688..9442
                     /locus_tag="TV191_001252"
     CDS             7688..9442
                     /locus_tag="TV191_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein"
                     /protein_id="HEL1507765.1"
                     /translation="MNKPLIKSCLLALLTLAGLTSMAAQADVNTYNQGRTYNDTPYYS
                     AYHHYYDHTRDTADNGIDNWGRLTRYHYYRETYYQLEAERQQLVRTYLELKASYDDQV
                     ALSSQRLQQYQSGWSDLQSRFEQLRKTNPVVGGDYRIVELEGNFQSYQTLLQQLSMAD
                     FVSQYKDRLDTLTRLDTERARLIDTWWESDSNYSDLNTNLTLVNGYIKELNQALQELL
                     KDHQGKMTSDLQTLGDRQAELARRLTDIESRPKRQATSQPRGSQTHWRSAPRADVALW
                     NELRNEGDYASATTDNALPLQPYRADLTAVHDLEALQAQSDRAHRLRAKEIVFTLQRS
                     NISRQGDIDLSGAITAFIKEKLLVTPNARGVSSGFRWQMQTYDNERLTITLMPQYYMT
                     DDQYKEYYDHLKAWTAQHIQSTDTEVEKIDKIQDYIMTNYHYATGKVGGVTRTGISVQ
                     TPYAFIKDKEAVCQAYAQMFKDMGRLAGLDVHYIQGYGDPVGGLSSLHAWNIVKVDGQ
                     YYHIDLTWNDTIDSTNHNHTYTLRGNDFMSKTHLWNAAYAISDSDYAAYPRRSFLRYG
                     TYATNYSRNTFYPGYSYA"
     gene            9583..9963
                     /locus_tag="TV191_001253"
     CDS             9583..9963
                     /locus_tag="TV191_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEL1507766.1"
                     /translation="MKSIRRYDVNEEWAHTGLVEAGDFYFLNYCVGNVGQDIEAQING
                     AFDEMERRLGLVGLTLEVVVQMDCLFRDIWNVPVMEKIIKERFNGKYPARKFLQTAFA
                     HQGGPDGLLFQVDGVAYSKHISVS"
     gene            10001..12334
                     /locus_tag="TV191_001254"
     CDS             10001..12334
                     /locus_tag="TV191_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL1507767.1"
                     /translation="MTFLELLQKKFFPKKYQEKQALKERAAQHMADKEATTQATATAL
                     ADQEAQAGQTERQSVLQRSKSYGVKRKNRPIWLQRLEAILPSQQGPIRRFLRRYHVGK
                     ILLILMGTFVLLLGSYLFYLSKTAKVSDLQDALKATTVIYDRKGEYAGSLSGQKGTYV
                     ELDAISDDLEKAVIATEDRTFYTNNGINFKRFLLAIVTAGRFGGGSTITQQLAKNAYL
                     SQEQSIKRKAREFFLALELTKKYSKNDILTMYLNNSYFGNGIWGVEDASQKYFGTSAA
                     NLTLDEAATLAGMLKGPEIYNPYYSIEKATNRRDTVLSAMVDAGKISKQQAQEAQAIG
                     MGNRLADTYVGKTDDYQYPSYFDAVINEAISRYGISEKDIVNDGYKIYTELDQNYQAG
                     MQTTFNEDSLFPVSEFDGSSAEAASVALDPKTGAVRGLVGRVNSTENQPFRSFNYATQ
                     AKRSPASTIKPLVVYTPAVAAGWSLEHELPNSVQDFGGYQPHNYGNYESETIPMYQAL
                     ANSYNIPAVSILDQLGVDKAFSYGEKFGLKMSETKKELGVALGSGVTTNPLEMAQAYA
                     VFANGGVKHIAHLITRIENAKGKVIKTFTDKTKRVISQSVADKMTSMMLGTFSNGTAV
                     NANVYGYTLAGKTGTTETDFNPDLSGDQWVIGYTPDVVISQWVGFNQTDEHHYLSDSS
                     AGTASAIFSTQASYILPYTKGSQFKVDNAYAQNGISAVYGINETNTQAGIDSQSIIDS
                     LRKSAEEASKSISEAVDQSGLREKAQSIWKSIVDYFR"
     gene            12383..12535
                     /gene="rpmG"
                     /locus_tag="TV191_001255"
     CDS             12383..12535
                     /gene="rpmG"
                     /locus_tag="TV191_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEL1507768.1"
                     /translation="MAQKKASLACVECGSRNYSIGISSTPRPTRLEVNKFCKYCKAYT
                     LHKETR"
     gene            12547..12723
                     /gene="secE"
                     /locus_tag="TV191_001256"
     CDS             12547..12723
                     /gene="secE"
                     /locus_tag="TV191_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEL1507769.1"
                     /translation="MGFISGIFKLLRDTTWPDRKQRWKDFISVLEYTAFFTVIIFIFD
                     QLLSKGILSLINLF"
     gene            13114..13659
                     /gene="nusG"
                     /locus_tag="TV191_001257"
     CDS             13114..13659
                     /gene="nusG"
                     /locus_tag="TV191_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEL1507770.1"
                     /translation="MLDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEI
                     PTQTVNVEKNGQVKEVEENRFPGYVLVEMVMTDDAWFVVRNTPNVTGFVGSHGNRSKP
                     TPLLEEEIRAILLSMGQTVDVFDTNIKEGDMVQIIDGAFIGQEGRVVEIENNKVKLML
                     NMFGSETLAEVELYQIAELSS"
BASE COUNT         4093 a         2661 c         3205 g         4405 t
ORIGIN      
        1 agaaagtaag cataagagcg acattgaaga ttatattaat cttgttaaac agcttggcaa
       61 ccctcagttt gcccaaattc tacatcggac gctatcagtg attctagata gttaatacta
      121 aaaaagtagc ccaatcgttt ggtggctaca gtggccaagg ccaccaaata gacaaaaggg
      181 ctaataagaa aataaaagct tttcgcataa tatctcacct ccttgataag gatattatac
      241 aaaggggaag cttcaatctc aaacattcgc aaatatgaaa atattaacaa aagcatcatc
      301 atatttgcga atatcgagaa tatgataatt gtcgtgatat aattactgtg ttaatgattt
      361 agctaggcat taataaatct aaatatagac tacaggcagg tcgctcgtta tactagtttg
      421 agggccaatg gtctgggtag gaggaagcgt atggcgacat tagagcgaca tcataaaatg
      481 ttattattgt caatggcatt aggggcagcg agctggttag cactcggatt gattagcttg
      541 ccaaatcttg caggtgcttt aggaataagt actgctaatg ccaatactac agttaatttg
      601 ttgagtgctt atagtacagt ttctagcgtt gttgcaatcg ttggtgctgt tacgggtgta
      661 gggtctattg gagctggaat tgcagctacc gttttatacc ttatcaaaca aaaaggaaag
      721 gctgctgctg ctctctggta gttaattgtc tgatatgaag catgttttca aatatcataa
      781 aggcgacatt ttagggtatc tcaatattgt tgggtttacc cttttgtttt atggctcagt
      841 gataggtatg ataatgttca gggattattt gacctatgat ggagctggtt ctctaatatc
      901 gacctttatt ctggtatcag gaacctatca ttctgtgaaa tcaacatttc catatgaagg
      961 gaagcgtcat ccaactttta tattaacacc ctattatcta tttaagcatc tattgctttc
     1021 agttacaaag gtttatgctt tccagatccg agtggttact ataggaatca tctgtttagc
     1081 aatagccttt ccggagcagc ttgtttggat agccttgtct gtgctagcag tatttatata
     1141 ttggctatcg cttccgctag tagccatttt tcgagtagct ggacgactcc tgaatcttct
     1201 catgatttat ggtatgtatc ttaatcagga gctgctggtc attgcttgtc tttgtttaaa
     1261 tgtggttatt cttgtgctta gtgttacgat taatgtacat tatccctacc aatggctggc
     1321 ggtgagagct aggaaggaag aaaaaacaat taccttgtta aagcttgtta tcaatacgat
     1381 aacagatcat ttagctttaa tggttctgtt tagtattttc tgtatagctg tgacctattt
     1441 cacgcaaagg ctgctgctaa gttttgatta ttctagcttt agcataccag tttttttctt
     1501 atctgcttct acctatatcg cgttactaga ggttatggtc ggtaaaaata ttaaggagct
     1561 tgagttagac cggggcttgg ctgttttaca gtttctgaat agggatatca gtgtttacaa
     1621 agcttatcgc aacagccaat tcttgctttc tgctcacatc ttagctgtta ttcatacagg
     1681 atgtgccata ggcttactac catttttact aaatggtcaa gctgctcttt ttctgtctaa
     1741 cctagtgatg atccccttca tctactttat atcattttgc tatttcgtga aatcactaaa
     1801 aatagttgct ggtgatttgt cagtgtttag gtgggttatt ctggttttgt attttatact
     1861 agtggtcatt gcaatggtag gtagtcgttt atgataatga ggaaattttt aagatattat
     1921 atcagtttta ttattttctc aatagcaatt gggattttaa tcggtttgct gatcaccagt
     1981 gatactgtca tattatctaa gccagagcgg ggctgggatt ttactctgga ggttttgaag
     2041 aataatagca ataatttttt gtcctatatt ttcctcttct ttttgtcccc agccttgcaa
     2101 ttgattgatt tggtatcagt tgttatacaa attactctag gaatgaggaa gtctggattt
     2161 ctaataactg ccttgggttt gtttccgcat ggtttgctgg agatccctaa ttttctcttt
     2221 tatcaaggct tgagtcaata tatgctatgg actgttttga ctgaaaaaag catgacgtcc
     2281 ttcttagaaa gagaaagaag atatgtaagg tactatctta tatcgtatta tgttttgtta
     2341 attgctggta ttatggaagg gttactcgga tgaaaatagt aaatgaaagc aagtcatttt
     2401 caaacagaaa aatcttaaat cacatatcct ttgactttag taaagggctg tataaggttg
     2461 aagggaataa tggtagtggt aaaaccactt ttttgcgctt gttagcaggc ttagaacggt
     2521 ttgatagcgg ccatcgctta cagcataagg gagatattct atatcttgat actaatgcta
     2581 tcggtgtagt tcccttaact attgaagaca atctgacatt attatggaaa acctttaatg
     2641 cctctcctga tgaggagacc ttgtctgtga ttaatcagtt ctttggagaa cggttactag
     2701 atcattatct gacggcttct gtaggaacaa aggctaaggt gggcttatcc ttgctttttg
     2761 taaaggattg ggattatatt ttcatagacg aagccctatc aacgcttgat gggtttagtc
     2821 ttgatatggt tgcaggaaga ttattagcat taaaagaaaa ggctactgtt ttttacgttt
     2881 ctcataatct atcacaccag cagctattgt cagaatcaca ggtgatttat cttaatggaa
     2941 aaggagaaat ctattgaaag gtaatccttt taatcgtaat ctttcttggt taatagccta
     3001 tgtgctatta ctttcttgtt atgtattcat attagtagat ggtggttttt taaaaaacag
     3061 cgttcaagaa ttggaagtcc tgctcggcca aacatcacta gctataaagc tgtttttgat
     3121 ggtgatatca atagctttta gcatcatatc tttactggtt gagtattttt taagcaaatt
     3181 tttagtgctg ctttttattg aagctggcat cgtttcttta aatgatgttc ttactgctaa
     3241 atcagtgact ttagtgatcc atttatctgc tttgctattg aagctatctc cctctccact
     3301 ttttcagttt gtagtgaatg ctttagggat tgtgatcatg tatggattga gtatcaagag
     3361 acaaggaaat aggacaactg ctcttttgtt ttgtttaccc tttacactgg atattctagc
     3421 aacattgttg ctttagtgat tttgagttgg aggaaaagta atgaaaaaaa tcttatattt
     3481 atcagtactt ttaggaacgt caattctagc aacattgatt aaaatttata acactttttt
     3541 tgcaaagcta aaggcttcat caggtcattc aactgggaat atagagattg atgccctttt
     3601 atctgagtct agactagtgt tggaaaggca gcatgccttc acaacaaatg gaatcaacaa
     3661 gctattcgtt atgatgatga gtctaatgct gttattagcc ttatactatc tgataaaaaa
     3721 ggatttgaag gccgtctata gttatttgct ttacctggtg ttaaccttgg ttcatgcaat
     3781 ttatagcttc ttttcgttaa gtcccttggc aaagctttat tctgatgata tgctgggggc
     3841 tacaatccag acgggagaga aagctaaatt gattttttca gtggttcttt ttcttcttta
     3901 tctgcttatt gttgtggcca ataatagagt aaaatctagt gtagaacccg cttcatctat
     3961 tgggatagat gtgtaatacc tttcatatta tgacctttaa agccttttag cttctctaat
     4021 tttcagagta actaggaggc tgtttgtgac gctctgagcg ttttttcgtt tctatcaaag
     4081 tttagctgcg ttaatgctat ctatttccgt agctgagata caagatatta taatatgtgt
     4141 tgtcatacca taaaaacacc ttacaggata ttttatgatc aatcctcctt gaattaagct
     4201 ttctttaagc aagggtgtgt atactagccg taatcctaaa taattggtta cctaatgata
     4261 actaattttt tcataacctc cttcctaaaa acgatgtcag ggcagtcagg attgattgct
     4321 gttatggcat cgtttttgtt gtactttgat aggggatcta gctgtatgtt aaatagccta
     4381 tcaggattga gtggcgaaga tgatcaggag tctcttggct ctaggttatg ctgctgtttc
     4441 atgagaaaca gctcttgatg atcaatttag gtagtattag tggtggtcat cttagccttt
     4501 taggctttga gctgctttat gtttgctcat ttttaatatg ttagtgttta cacaaataat
     4561 tctcattttt tgatataata gaaaaggtaa ggaagggtag gagataagga tgacaagatt
     4621 ttttcaaaaa aaacaggcca aaagcttagc cattggtttt gtgagcttgt ttgctgtgct
     4681 cattgggtat ggagcttttc actattctaa ggccagtcgt atcaatgcct atctacaagc
     4741 aaggtcatca ggctctgggc aggtgcttga aaatatcaag gaatacctcg tgtgggcaga
     4801 taccaatgag cagctgacca atgatcaagc aagatacacc agctttaaga gatacagtaa
     4861 ggcagagcta gtaagcaagc gtcagcagct gcaaacagca actgcagctg atgatatgta
     4921 tgtcaaatcg gttggtcgca aatttttgat tttccctgat tatcgcatag cagtgaagcc
     4981 tgtagccttg acaatcaaga ccaatgtgcc aaatgttgat atcttgttga accataaaaa
     5041 gattgctgta tcacagtcag aggattttag cacaactatt gaaagactgc cggctgctga
     5101 ttataaggcg agtattaatg gctattataa ggatcgtaag attaaagtca gcaaggccta
     5161 tgatggcaag aaccatacac tagatttgag ggttaccttt aagacattta cggtaaccag
     5221 caatgtcaga gatggcgagc tttatattga tggcgagcgc gtggaaactt tgaaggctgg
     5281 gcagcttcag ctggaagaat accctgtgac agaaatcgca aaggcctata ttaaaaagac
     5341 ctttcctgat ggcgagctaa cctccagcaa gcattccctt gctcctgttg ctgagggctc
     5401 ccagctagag attaacattg atcacctctt gactgaggaa caggcgggac aggtgttggt
     5461 ggcagccttt gatcaattgc tcacctatct caatcaaggg caggatccag caggtctttc
     5521 aactgttttt gagcaagggg ctaataatgc tttttacaaa ggcttgaagg attccatcaa
     5581 agcaaaattt caaactgata ccagaaaggc ttctcggtta agcattccgt ctattttgtt
     5641 aagtaagcta actcaaattg gtaagcagtc ttatctagtg gactttacag ctgtttatga
     5701 ttttgtttac gataaggaaa ctgatcctga aaaaggcacc tcagggaatg ttcgtcaaga
     5761 cttgactggt aagctgaccc tgaaaaaatc tggggatagc taccttgtta gtcagtctgg
     5821 tcctaaaaat attacagttg ccagcgaaaa aaatcaggtc aagccgtcta ttttcccaga
     5881 ggggctagtg ggaacctgga taggacatcg ttcggacatg acctttacga tgatattggc
     5941 taaggacggc agcatcacaa caaccattgg aaacaaaaat gggaatggct cacagaccac
     6001 taagtctgct aaaattacca aggtagagga aaaaggagat ggcttgttcc tctacactgt
     6061 agctccagat gctgatatag cagctcttgt tccaggaggt ggattgggtg gtgtcaatgt
     6121 caaatacgct tttggtgtca aatggagtgg agatgtcgct acgatagtgg tttggcagac
     6181 agcaaataat gcggcatttg attacagtaa gccaatgctt ggccctgaca tgaaaaagca
     6241 ataagtactt taccctacaa gttggtctag catttattgc taggaggaat cagcataaag
     6301 aaaaagcctc tcttttaatc ttttgtggtt aagaagagag gctttttagt atagggctga
     6361 ctgtatgagg agcaaccgat gtaatcaatt tagctgctgt agtccttctt taaagctttt
     6421 agacggggca gtgaccctaa tcatctcttg agccaagggg tgtctaaggg ttagctgatg
     6481 agcgtgcagc atgagacgct ccgctttttg cctgctatag aggggatcac caattagagg
     6541 gtgtttatga tgagcgagat gtactctgat ttgatgtgtt cgtcctgtct ctaggcgaca
     6601 gttgactagg caggtctgat caaaggcttg taataaggct agatgggtga ttgcctcttg
     6661 cccatgctta ctatcaacca cacgcttgcg cctatcgtgg cggtgacgtc cgattggatc
     6721 gcgataggtt actgtttgct gctctagctg accttcgatt agggcccaat aatctcgctt
     6781 aatgtctcga tgctccaata ggcgatttaa gatcggaagg ataaagggat ttttagcaaa
     6841 gagaatcgct ccactagtct ccatgtctaa gcgatgaacc acatagcagg tcttgccagt
     6901 ataggcagag acatggttga gcaaggcgag ctcagtgggc tcattgccat gtgttttcat
     6961 gccctcgggc ttgttgacaa tgatgaggtg ttcgtcctga tacaggcaat ccactaggcc
     7021 aggcttaccc attaagatgc ctttatcagg gtagtcttct tggtcaaatt gtagcttgat
     7081 gtgatcaccc tgcttgacag ggctctgcca gttaatcagc tcatcattga cccaaacatg
     7141 ctttttgatg cgcaagaaat gtctgatttt acggggaatc aatagcctat cttctaataa
     7201 ctccttgaca gttgtcgctt gataggggtt aatgaaggag atctgaaagc ccatctcagg
     7261 cttatttgct gttgtcattg agccagtcat ggtatttttc aatcaaattg atggccattt
     7321 gggttgcaag agttacagag aaagcctcgg ttccctcgcg ctcgtcactg gcaacctcta
     7381 agcgtgtctc atcatagaca gccttgaggc tctctgctga cagggtttct ttaaaagctt
     7441 gaaatttgtt catgatcatg tcctaccttt ctaaatgttt gtgacaatgc tattatagca
     7501 tatttttcat caaagctaat catttgctcg atgatttgtg ctgcgctaac agcgtgattc
     7561 ttttgagaaa aaataagatt agctattgtg aaattgtctg tcttttatta tactaagaat
     7621 agtctgataa atatattatt taaggacacg ataacattgg gattatgaat catttaggag
     7681 aatactattg aacaagccat tgataaaatc ctgtttgctt gctctattga ccttggccgg
     7741 cttgaccagt atggcagcac aggctgatgt caacacttac aaccaaggta ggacatataa
     7801 cgatacaccc tattattctg cttatcatca ctactatgac cacacgaggg atactgctga
     7861 caatggtatt gataattggg gtcgtctgac acgctatcac tattacagag agacctatta
     7921 tcagcttgag gccgagcgtc agcagcttgt taggacttac ttggagttga aggcttcata
     7981 tgatgatcag gtggctctta gcagtcaacg actacagcag taccagtctg gctggtctga
     8041 tctccaatca cgctttgagc agctcaggaa aaccaatcct gttgtaggcg gtgattatcg
     8101 gattgttgag ctagagggca attttcaaag ctatcagacc ttgctgcagc agctttctat
     8161 ggctgatttt gtcagccagt acaaagatag gctggatacc ttgactagac ttgatacaga
     8221 gcgagctagg ctcattgaca cctggtggga aagtgatagc aattactcag atctcaatac
     8281 caatctaaca ctagtcaatg gctatatcaa ggagctgaat caggctttac aggagcttct
     8341 taaggaccat caaggtaaaa tgacatcaga tctgcagacc ttgggtgacc gacaggccga
     8401 gcttgctaga cggctgacag atatagaaag caggcctaag agacaggcta ccagtcaacc
     8461 tcgtggttca cagacacatt ggcgatcagc ccctagagct gatgttgcct tgtggaatga
     8521 attgcgaaac gaaggagatt atgcttctgc tacgacagac aatgctttgc cattgcagcc
     8581 ttatcgagcg gacttaacag ctgttcatga tctagaagcc ttgcaagcac aatctgatag
     8641 agcacaccgc ttgcgggcaa aggaaattgt ctttacactg cagcgttcta acattagtcg
     8701 tcagggcgat atagatttgt caggagccat tacagcattt atcaaagaaa agcttctcgt
     8761 cactccaaat gcgcgtgggg tatcatctgg ctttaggtgg caaatgcaaa cctatgacaa
     8821 tgagcgctta accatcactc taatgcctca atattatatg actgatgatc agtacaagga
     8881 gtattacgac catctcaagg cttggacagc tcagcatatc cagtctaccg atacagaggt
     8941 tgagaaaatt gataagattc aagactatat catgacaaac taccactatg cgaccggcaa
     9001 ggttggagga gtgacccgta ctggcatttc tgtgcagacg ccatatgcct ttatcaagga
     9061 caaggaggct gtttgtcagg cctatgcaca gatgtttaag gacatgggac gactagctgg
     9121 acttgatgtt cattatattc aaggctatgg agacccagtt ggcggcttat caagtctaca
     9181 tgcttggaat atcgtcaagg ttgatggtca atattatcat attgacctga cttggaatga
     9241 tactattgac agcaccaatc acaatcatac ctacaccctg cgaggcaatg attttatgag
     9301 caaaacacat ttgtggaatg ctgcctatgc gatctcagat agtgactatg ctgcttatcc
     9361 taggaggagc ttcctgagat atgggaccta tgcgactaac tattcaagaa atacatttta
     9421 tccaggatac agttatgctt aataatagct aataccatca aaagccctag aaagcttgct
     9481 tgattctttc agggcttttt gatatgtcat ggtttttggt ataggatttt gaaagaaatt
     9541 gttataatag gataaaatgc ttatgtaaca ggagaaaata aaatgaagag tattagacgc
     9601 tatgatgtca atgaagagtg ggcacatact ggcttagtag aggcaggcga tttttatttt
     9661 ttaaattatt gtgtaggaaa tgtcggtcaa gatattgagg ctcaaattaa cggtgccttt
     9721 gatgaaatgg agcgtcgttt ggggctggta gggctgacgc tagaggtcgt tgttcaaatg
     9781 gattgcttgt ttagagacat ttggaatgtg ccagttatgg aaaaaatcat caaggagcga
     9841 tttaatggca aatacccggc tcgtaaattt cttcaaacag cctttgctca tcagggtggt
     9901 ccggacggct tgctatttca ggtagatggg gttgcttatt caaagcatat ctccgtatcc
     9961 taaacaatat gacttggagg cttagtagta tcataaggct atgacatttt tagaattatt
    10021 acaaaagaaa ttttttccaa aaaaatacca agaaaaacag gccttaaagg aaagggcagc
    10081 ccagcatatg gctgacaaag aggctactac tcaggctact gccactgctt tggccgatca
    10141 ggaggcacag gcagggcaga ctgagaggca atcagtcctt caacgcagca agtcctatgg
    10201 ggtcaaaagg aaaaatcggc cgatctggct tcaaaggctg gaggcgattt tgccatcgca
    10261 gcaaggtcct attcgccgct ttcttcgtcg ttaccatgtt ggtaaaatcc tgctgatttt
    10321 gatgggtacc tttgtcttgc tgctggggtc ttaccttttt tacctttcaa agacagctaa
    10381 ggtttctgac ttgcaggacg ctcttaaggc gacgacagtc atctatgacc gcaagggaga
    10441 atatgcaggc agtctttctg gtcaaaaggg gacctatgtg gagcttgacg ctatttcaga
    10501 tgatttggaa aaggcggtta ttgccacaga ggaccgtacc ttttatacca acaatggtat
    10561 taatttcaag cgctttttat tggctattgt gaccgcagga cgctttggtg gaggctcgac
    10621 cattactcag cagttggcta aaaatgctta tttgtcccag gagcagagca ttaaaagaaa
    10681 ggcgcgtgag tttttcttag cacttgaatt gaccaagaaa tacagtaaaa atgacatttt
    10741 gaccatgtat ctcaataatt cctattttgg aaatggtatt tggggtgttg aggacgccag
    10801 tcaaaaatat tttggtacct cagcagctaa tctaaccttg gacgaggcag caacccttgc
    10861 cggtatgctc aagggacctg aaatttacaa tccctattac tcaatcgaaa aggcaaccaa
    10921 ccgtagagat actgttttgt cagccatggt tgacgctgga aaaatcagca agcagcaggc
    10981 acaagaggcc caagctattg gtatggggaa ccgtttagca gacacctatg tcggcaagac
    11041 agatgattat cagtacccat cttattttga tgctgttatc aatgaggcta tctcgcgcta
    11101 tggcatctca gaaaaggata ttgtcaatga tggctacaag atttacacag agttggacca
    11161 aaattaccaa gcaggcatgc agaccacctt taatgaggat agcctatttc ctgtgtctga
    11221 gtttgacggc agctcagctg aggcggctag tgtggctcta gatcctaaaa ccggagctgt
    11281 cagggggctt gttggtcgtg tcaatagcac agaaaaccag ccctttagaa gctttaacta
    11341 tgctactcaa gccaagcgta gccctgcttc aacgatcaag cccctagttg tttatactcc
    11401 tgctgttgca gcaggctggt cactggagca cgaactgcca aacagcgttc aggattttgg
    11461 cggttatcag ccgcataatt atggcaatta cgaatcagaa acaattccta tgtatcaggc
    11521 tttggctaat tcctacaata ttcctgctgt ttcaattctg gatcagttgg gggtggataa
    11581 ggcctttagc tatggtgaaa aatttggttt gaagatgagt gaaaccaaaa aggagcttgg
    11641 agtggcgctt ggtagtggtg tcaccaccaa tccgcttgag atggcacagg cctatgcagt
    11701 ctttgccaat ggtggtgtca agcatattgc ccacctgatt accagaattg aaaatgctaa
    11761 gggcaaggtt atcaagacct ttacagacaa aaccaagcgg gttatcagtc aatcagtggc
    11821 tgataagatg actagcatga tgcttggaac cttttctaat ggtacagctg ttaatgccaa
    11881 tgtctatggc tatactctgg ctggtaaaac agggaccaca gaaactgact ttaacccgga
    11941 cctttccggt gatcagtggg tcattggcta cacgccagac gttgttatca gtcaatgggt
    12001 tggcttcaat caaaccgatg agcatcatta tttatcagat tcaagtgcgg gcactgcctc
    12061 agcaattttt agcacccaag cctcttatat attgccatat accaaaggaa gccaattcaa
    12121 ggtcgataac gcttacgctc aaaacggtat ttcagcggtt tatgggatta atgagaccaa
    12181 tacgcaagca ggtattgatt ctcaatccat cattgatagt cttagaaagt cagccgagga
    12241 agcttcaaag tctatttcag aggcagttga tcaatctggt ctcagagaaa aggcgcaaag
    12301 tatctggaag agtattgttg actactttag atagcttgcg aaaatatcta aatcgtgtta
    12361 gaataatcac tacggaggcg ttatggcaca gaaaaaagca agcctagcgt gtgtagaatg
    12421 tggcagccgc aattattcta tcgggattag tagcacgcct agaccaacac gactagaagt
    12481 caataagttt tgcaaatatt gtaaagcata caccttacac aaagaaacac gttagaggag
    12541 agcctgatgg gattcattag tgggattttt aagcttttaa gggatacaac ttggccggat
    12601 cgtaagcagc gctggaagga ctttatttct gtccttgagt atacagcatt ctttacggta
    12661 atcatcttta tctttgacca gttgctatca aaaggcattt tatcattgat taatttattc
    12721 taagtcattg caatgatgag acctgttatg attaaaattg cttggaaaag cctaggctga
    12781 aacaatcgtt tcggcctttt tgagtgcgat gggcaggttg tactctgata gatgcaagac
    12841 caatagacca cctactatgc gggtgcgtaa aggggttgat agctaccgat agttaagggc
    12901 tatagcaagt agaaaggctt gcagctcagc tgatccgctg ttatgactaa aggcattgac
    12961 cagaaaggtt cgttggcagc caacaaagtg ctcttaccct gctatgaggg gctattaatg
    13021 cgttgacagc caatccttct tctattataa tgaaagtgtg ataacagcaa tgcaaaggcc
    13081 agcagaggct tttttataat gaaaggaagt aacatgttag attcttttga taagggctgg
    13141 tttgtccttc aaacttactc aggctatgaa aataaagtaa aagaaaacct tttgcagcgt
    13201 gctcaaacct ataacatgct agacaatatt ctccgcgttg agattcctac ccaaacggta
    13261 aatgttgaaa aaaatggtca ggtcaaagag gttgaggaaa accgcttccc aggatatgtt
    13321 ttggttgaga tggttatgac tgatgacgct tggtttgttg ttcgtaacac accaaatgtg
    13381 acaggctttg tcggatcgca tgggaaccgc tcaaaaccaa cccctctact tgaagaggag
    13441 attcgtgcta tcctgttgtc aatgggacaa actgttgatg tctttgatac caacattaaa
    13501 gagggcgata tggttcaaat cattgatggc gcctttatcg ggcaagaggg tcgtgtcgta
    13561 gaaattgaaa acaacaaggt caagctcatg cttaatatgt ttggctcaga aaccttagca
    13621 gaggtcgagc tttaccaaat cgcagagcta tcgtcctgat aggctcctaa agctattatt
    13681 cataccataa aaaataaaag gctggcatcg gctctctaaa ataccgatgt taggcctttt
    13741 ttgttggtct tctacaacca agactcaaat taaccaaacc ctaaaaagag tcatttttcc
    13801 ttcgcttttt aagtctctaa ctgatcgccc tagcttattt ttaatctagt aatcgcaaca
    13861 ggtcaagagt taaatgatat cgcgccgtta ttgattggta tagacaaaaa tacgctcaaa
    13921 aaaagaaaaa aggataggta atatagtcct ggtttgcttg atagatggtg gttggcaacc
    13981 aaccattcga gtactttcct taactataaa ctcctaatca attctagcgt ttaaaaaata
    14041 agattattct tggagggaag caaagagctt ctctcctttt tgagttgtag cattcttgat
    14101 cctgatctta taagcagagt cctgtttgcc gggctgttga gatgaataag ggcatttcta
    14161 tagtgattat atagtgttgc agatgtgtgt atggtttaag gtctaaatac ccttcaagct
    14221 tagttcttgg gtagtcagtt cggattggct ggctgatttt taagccttta atggcttagt
    14281 ggtaagacaa accagattac atttgctaaa aagtccctaa ggctacaatc attttttgtg
    14341 actaatataa aaactagacc tttt
//
LOCUS       DARYXW010000051        14063 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.051, whole genome shotgun sequence.
ACCESSION   DARYXW010000051 DARYXW010000000
VERSION     DARYXW010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14063)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14063)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14063
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.051"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            124..684
                     /gene="ahpC"
                     /locus_tag="TV191_001258"
     CDS             124..684
                     /gene="ahpC"
                     /locus_tag="TV191_001258"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002273221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HEL1507771.1"
                     /translation="MSLVGKEIAEFSAQAFHNGKFITVTNEDLKGKWAVVCFYPADFS
                     FVCPTELGDLQEQYEILKSLGVEVYSVSTDTHFVHKAWHDDSDVVGTITYPMIGDPSH
                     AISQAFDVLGEDGLAQRGTFIIDPDGVIQMMEINADGIGRDASSLIDKIRAAQYVRKH
                     PGEVCPAKWKEGAETLTPSLDLVGKI"
     gene            705..2237
                     /gene="ahpF"
                     /locus_tag="TV191_001259"
     CDS             705..2237
                     /gene="ahpF"
                     /locus_tag="TV191_001259"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HEL1507772.1"
                     /translation="MALSPDIKEQLAQYLNLLESDLVLQAYLGSDDSSQKVKDFIEEI
                     AAMSDRITVEETTLTRQPSFKITQKGQDSGVIFAGLPLGHEFASFILALLQVSGRAPK
                     IEQDIIDRIRAIDRPLSFETYVSLTCHNCPDVVQALNIMAVLNKNISHTMVEGGMFQE
                     EVKAKGIMSVPTVFLNGEEFTSGRATIEQLLEQIAGPLSKEAFADKGVYDVLVIGGGP
                     AGNSAAIYAARKGLNTGLLAETFGGQVMETVGIENMIGTLYTEGPKLMAQVEEHTKSY
                     DVDIIKAQLATSIEKKDLVEVTLANGAVLKAKTAILALGAKWRSINVPGENEFKNKGV
                     TYCPHCDGPLFEDKNVAVIGGGNSGLEAALDLAGLAKHVYVLEFLPELKADKVLQDRA
                     AKTDNMTILKNVATKDIVGDDHVTGLNYIERDSNQEKHLDLEGVFVQIGLVPNTAWLK
                     DSGISLTDRGEIIVDKYGSTNIPGIFAAGDCTDSAYKQIIISMGSGATAAIGAFDYLI
                     RQ"
     gene            2698..3468
                     /gene="rpsB"
                     /locus_tag="TV191_001260"
     CDS             2698..3468
                     /gene="rpsB"
                     /locus_tag="TV191_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEL1507773.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKLADQAYEFVRDAAANDAVILFVGTKKQAAEAVADEATRAGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEEGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNADPDDIDVIIPANDDAIRAVKLITAKLA
                     DAVIEGRQGEDAEVAFEADTQAESIEEIVEVVEGSNEA"
     gene            3636..4676
                     /locus_tag="TV191_001261"
     CDS             3636..4676
                     /locus_tag="TV191_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEL1507774.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDMEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVVEVNAETDFVAKNAQFVELVNATAKAIAE
                     GKPANNDEALALIMPSGETLADAYVNATATIGEKISFRRFALVEKTDDQHFGAYQHNG
                     GRIGVITVVEGGDEALAKQVSMHVAAMKPTVLSYTELDPQFIKDELAQLNHAIELDNE
                     SRAMVNKPALPFLKYGSKAQLSADVIAQAEEDIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLDSVNAKAISFARFEVGEGIEKKANDFES
                     EVAATMAAALNN"
     gene            complement(4876..6771)
                     /locus_tag="TV191_001262"
     CDS             complement(4876..6771)
                     /locus_tag="TV191_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase"
                     /protein_id="HEL1507775.1"
                     /translation="MTTYQEDFYQAVNGQWAETAVIPDDKPRTGGFSDLADEIEDLML
                     TTTDAWLAGEHVPNDAILENFVKFHRLVADYDKRDQVGVAPALDLIEEYKALGSFAEF
                     ASKVADYELNGKPNQFPFSVAPDFMNAQLNVLWAEAPGLILPDTTYYAKDNDKGKELL
                     AIWRGMQEELLPKFGFSHEEVKDLLDKVITLDKQLADYVLSREEYSEYAKLYHPYDWA
                     EFTKLVPELPLDNIFTVILGEVPDKVVVPEERFWTEFAADYYSEKNWELLKAWLVLTA
                     AGAYHAYLTDEIRVLSGVYSRALSGTPQAMDKKKAAYYLAQGPFNQALGLWYAGEKFS
                     PEAKADVEHKVAKMIEVYKSRLETADWLAPATREKAITKLNVITPHIGYPEKLPETYA
                     KKVIDDKLSLVENAQNLAKISIAHSWSKWNKPVDRSEWHMPANMVNAYYDPQQNQIVF
                     PAAILQAPFYSLSQSSSANYGGIGAVIAHEISHAFDTNGASFDEHGSLKNWWTDEDYA
                     AFKERTDKIVEQFDGLDSYGAKVNGKLTVSENVADLGGVACALEAAQSEPDFSARDFF
                     INFATIWRMKAREEFMQMMASIDVHAPGQWRTNVTLTNFDEFHQEFNIKEGDPMWRAP
                     EDRVIIW"
     gene            complement(7323..8255)
                     /locus_tag="TV191_001263"
     CDS             complement(7323..8255)
                     /locus_tag="TV191_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEL1507776.1"
                     /translation="MTRASQEMRHVYRDFLIAANQEHPEVVVLEADLSSSMATNHLDQ
                     VFGKRYINVGIMEAEMVGLAAGLAIKGYKPYLHTFGPFASRRVFDQLFLSLAYAQLGA
                     TVIGSDAGVSAEMNGGTHMPFEDLGLLRLIPRAIVYEVSDDVQFKAVLKETLSLDGLK
                     YIRTIRKKPEAIYQGHEDFSNGYCLLRQGKDLVLACSGIMVKRCLEVADKMAEQGYSI
                     GVIDVFRVKPLADELKGLLTGSPVLTVENHNRIGGLGSAICELLAQESNTPVYRMGVD
                     ERFGQVGQMDYLLEEYQLTPAAIEQQVLRILAAD"
     gene            complement(8252..9109)
                     /locus_tag="TV191_001264"
     CDS             complement(8252..9109)
                     /locus_tag="TV191_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEL1507777.1"
                     /translation="MVLSDEPLTDVKRFAAEIRLNTLETLNHLGFGHYGGSLSIVELL
                     AVLYGEIMPMTPELFVQSDRDYLVLSKGHAGPALYSTLYLKGFFDKAFLQSLNTNGTS
                     LPSHPDRLLTPGIDMTTGSLGQGISVATGIAYAQALEQSPHYTYAIVGDGELNEGQCW
                     EAIQLAAHQQLSHFIVFVDDNKKQLDGTTEAICRPGDFVEKFTAFGFESLRVDGRDVQ
                     AIFEAIRALQASSSHKPKCIVLDTVKGQGVSQLESMAANHHLRPTAAEKEMLAAAVRK
                     LRASLEVTR"
     gene            complement(9112..10455)
                     /locus_tag="TV191_001265"
     CDS             complement(9112..10455)
                     /locus_tag="TV191_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEL1507778.1"
                     /translation="MTFLLDIVSTPAILVALIAIVGLLLQKKPAPDIVKGGIKTFVGF
                     LVVSGGAGIVQGSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATALIMFTGMI
                     FNILIARFTRFKYIFLTGHHTLYMACMIAVIMSVAGLTSVSLIVFGGLALGIIMSVSP
                     ALVQRYMIQLTGNDKVALGHFSSLGYWLSGFVGGLVGDKTKSTEDIDFPKSLAFLRDS
                     TVSITLSMAIIYLIVAIFAGPTWISKELSSGTHGLVFALQLAGQFAAGVFVILAGVRL
                     ILGEIVPAFKGISEKLVPHSKPALDCPIAYPYAPNAVLIGFVSSFVGGLVSMAVMIVS
                     GTTVILPGVVPHFFCGATAGVIGNASGGVRGATVGAFLQGVLISYLPIFLMPVLGGLG
                     FEGSTFSDADFGLSGILLGTLNSIGGVTAIVIGIFVILAGLVGLSVVGKSVAKEE"
     gene            complement(10468..10755)
                     /locus_tag="TV191_001266"
     CDS             complement(10468..10755)
                     /locus_tag="TV191_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1507779.1"
                     /translation="MALRIGTACGSGLGSSFMVQMNIESVLKDLGVTGVEVEHYDLGG
                     ADPTAADVWIVGRDLADSAEHLGDVRILNSIIDMDELTSLVKAICQEKGLV"
     gene            complement(10757..12799)
                     /locus_tag="TV191_001267"
     CDS             complement(10757..12799)
                     /locus_tag="TV191_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEL1507780.1"
                     /translation="MVDSKAVVILMTLMTYQDLSLYELSVKTKFTIREIKDRIDELNE
                     FLAQHELSELDATRSGYRISQQLKAESDHLFTLINAEQVYLSQAERINLIYLYTFCRR
                     DFVSNSHYQDFLKVSKNTALTDIKALRQKLADVDLELKYTRASGYILVGDEINKHRLA
                     LVMIATLLKSPIGLWALDYILASWHYQVSFEALEKRVSHFYQTFQMSPILDRLQVCLY
                     AVIFILCRYQRRVDRVKQRQVVVSEQLDQLTALLVAEIMQQLSLKYQLFEADEAYFQL
                     LLAGCFEGEGTVGDDFFESLTVAIVDQMQGVALLSFSQADQLKENLKRHLIPAYYRLR
                     YGLPSDNDYTLRIKDSYSELFDLVKQSLEPLAKELGSPIPDSEIAYFVLHFGGYLKQQ
                     GRDFHRQAYQAVIVCPNGVSSSLMIKEHLKLLFPDIAFRGLSRLDQLGQLDKSGYDLV
                     FSTIRLETDKPFYLVPMIMTDEQAFQLVSLVNRDFPDIGYRLEVEELLHLISSYAVIH
                     QKEKLRFALQQYLRQGVKRKDIRPVLQDLITKKTYQSTSEQLGWREAIYLAAQPLLES
                     GQIQASYPEAMIAKVEEFGTFINLGKGIAIPHARPEDGVNQVGMSMLVLEHPIYLLDD
                     PKQEIRLLICIAAIDNETHLKALSRLTTILRDNEQVKALLASKSFEDIKTIIAEEA"
     gene            13322..13912
                     /locus_tag="TV191_001268"
     CDS             13322..13912
                     /locus_tag="TV191_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507781.1"
                     /translation="MKKVKQLIIAMIASLLLIANTVPSIVYASEVTKIQQEEKVIEEK
                     LSQPLEISKSELDTLIQEKKALYPNLTEQEMREIAYKAMSPYTFRASVWDGQGVTLDE
                     FAWAFDVIVGGLISGYATIGKYVAKHGVAAARAVLSRAAKAAAQRLGVLTGFISGLLR
                     AAFSVINIYYNVGYALAQYVDARDYHPNNGRINAWA"
BASE COUNT         4349 a         3177 c         2768 g         3769 t
ORIGIN      
        1 ttcacatatg aaattgttag aaaagaacat caaaaacctt gataaatcta gggtttacaa
       61 gtggacagat aagatttctt agcttataat acaggtatca aatgtaaaaa aggaggacat
      121 gacatgtctt tagtaggaaa ggaaattgct gaattttcag cccaagcttt tcacaatgga
      181 aaatttatca ctgtaactaa tgaggatctt aaagggaaat gggcagttgt ttgcttctac
      241 ccagcagact tttcttttgt ttgcccaaca gagctaggtg accttcaaga gcaatatgaa
      301 atactaaaat ctttaggtgt tgaggtttat tctgtatcta ctgatacaca ctttgttcat
      361 aaggcatggc acgatgattc agatgttgtc ggaacaatca cttacccaat gattggtgac
      421 ccatcacatg ctatttcaca agcctttgat gttcttggtg aggatggact tgctcaacgc
      481 ggtactttca ttattgatcc agatggtgtt atccaaatga tggaaatcaa tgctgatggt
      541 atcggacgtg atgcaagcag cttgattgat aagattcgtg ctgctcagta cgttcgtaag
      601 cacccaggtg aagtatgccc agccaaatgg aaagaagggg ctgaaacact aacacctagc
      661 cttgaccttg tcggcaaaat ttaagcaggc aaaggagaaa agctatggca ttaagtcctg
      721 atattaaaga gcagcttgct caatacctta atcttttgga atctgactta gtcctacaag
      781 cttatcttgg tagtgacgat agctcacaaa aggtcaagga cttcattgaa gaaattgctg
      841 ccatgtcaga ccgtatcact gttgaggaga ctaccctaac acgtcaacca agctttaaga
      901 ttacccaaaa aggtcaagac agcggagtga tctttgctgg actgcctcta ggtcacgagt
      961 ttgcctcctt tatccttgct ctattacagg tttcaggacg tgcaccaaag attgagcagg
     1021 atattattga ccgcatcagg gctattgacc gtcctttaag ctttgaaacc tatgtcagct
     1081 taacgtgtca taattgccca gatgtggtcc aagccttgaa cattatggct gttcttaata
     1141 agaacatttc acatactatg gttgagggtg gtatgttcca agaggaagtc aaggcaaagg
     1201 gcatcatgtc tgtgccaact gtctttttga atggagaaga attcacctct ggtcgcgcca
     1261 ctattgagca gctgcttgag caaatcgcag gacctctatc taaggaggcc tttgctgata
     1321 aaggagtcta tgacgtcctt gtcattggtg gaggacctgc aggaaatagt gctgccatct
     1381 atgctgctcg taaaggctta aatacaggtc ttttggctga gacctttggt ggtcaagtca
     1441 tggaaactgt aggtatcgaa aacatgatag gaaccctgta tacagaggga ccaaagctta
     1501 tggcccaggt tgaggagcat actaaatcct atgatgttga catcatcaaa gcccagctgg
     1561 ctacttcgat tgagaaaaaa gaccttgttg aggttactct tgctaatggc gctgtcttga
     1621 aggctaaaac agctattcta gcgcttggtg caaaatggcg cagtatcaat gttcctggcg
     1681 aaaatgagtt taaaaataaa ggagtaacct actgcccaca ctgtgacggt cctctctttg
     1741 aagataaaaa cgttgctgtt atcggtggtg gtaactctgg acttgaggct gcacttgatt
     1801 tagctggctt agctaagcat gtctatgttc ttgagttctt acctgagctt aaggccgaca
     1861 aggtgctaca ggatcgcgct gctaaaacag acaatatgac tattctaaaa aatgttgcta
     1921 caaaggatat tgttggggac gatcatgtca cagggcttaa ctatatcgag cgtgacagca
     1981 atcaagaaaa gcatcttgac cttgaaggag tctttgtaca gattggcttg gtgccaaata
     2041 cagcttggct caaagacagc ggtatcagct taaccgatcg tggcgagatt attgttgata
     2101 aatatggttc aaccaatatt ccaggtatct ttgccgcagg cgactgtaca gattcagcct
     2161 acaaacaaat tattatttct atggggtcag gtgctactgc tgctattgga gcatttgatt
     2221 acctgattcg tcagtaagtt agcaaaaaac caaggtaact gtttaccctg gtttttgctt
     2281 tttagaggcc taataaacag caaggctgat agatcaagca tttggggtac gccaaatgct
     2341 tgaagaaact tatgttctct gatatctttt catgattcat gtgttctttt tcagaaagat
     2401 tgatagtaaa actaagctgc gcttgaaaaa tggatcgtgt caaaacgtca acatatcaaa
     2461 aatgcattga aaacatgcat atggttagaa aataatggca tgcattttcc tcatgcgtac
     2521 gacgtgggtt ttagtgtatt taggcttgct atgactagct ttttttggta tactgttgta
     2581 gttgtgcaga caacaaatac tcatcttaga tcgattgtga ttctgttgcc atcaggtgga
     2641 gttgcaagcc gacgtctaag agaggaaaaa aacatttcta taaaggagaa actactcatg
     2701 gcagtaattt caatgaaaca acttcttgag gctggtgttc actttggtca ccaaactcgt
     2761 cgctggaacc ctaagatggc taaatacatc ttcacagagc gtaacggtat ccacgttatc
     2821 gacttgcaac aaactgtaaa attagctgat caagcttacg agtttgttcg tgatgcagca
     2881 gctaatgacg ctgttatctt gtttgttggt actaaaaagc aagctgctga agcagttgct
     2941 gacgaagcta ctcgtgcagg tcaatacttc atcaaccacc gctggttggg tggaactctt
     3001 acaaactggg gaactatcca aaagcgtatc gctcgtttga aagaaatcaa acgcatggaa
     3061 gaagaaggaa cctttgaggt tcttcctaag aaagaggttg cacttcttaa caagcaacgc
     3121 gcacgtcttg aaaaattctt aggtggtatt gaggatatgc ctcgtatccc agatgtgatg
     3181 tacgttgttg acccacacaa agaacaaatc gctgttaaag aagctaagaa gcttggtatt
     3241 ccagttgtgg caatggttga tacaaatgct gacccagatg acattgatgt gatcattcca
     3301 gctaacgacg acgctatccg cgctgtcaaa ttaatcactg ctaaattggc tgatgctgtt
     3361 atcgaaggcc gtcaaggtga agacgcagag gttgcatttg aagctgatac tcaagcagag
     3421 tcaatcgaag aaatcgttga ggttgttgaa ggttcaaacg aagcttaagt caggcttatt
     3481 gaactaggat agcttcttgc tattcataac atggtctaac ggggcaaagc attccgctct
     3541 atctcgttat tttttaagta agaaaaccca gcaggtcaaa ggctctgcta aagcgagctt
     3601 taagaggacc gattctaatt ttggaggaaa taaaaatggc agaaattaca gctaagcttg
     3661 taaaagaatt gcgtgaaaaa tctggtgccg gcgttatgga cgctaaaaaa gcacttgttg
     3721 aaacagatgg cgacatggaa aaggctattg agcttcttcg tgaaaagggt atggcaaagg
     3781 ccgctaaaaa agctgaccgc gttgctgctg aaggcttgac aggtgtttat gttaatggta
     3841 acgttgctgc tgttgttgag gtcaatgctg aaactgactt cgttgccaaa aacgctcaat
     3901 tcgttgaatt ggtaaacgca actgcaaagg ctatcgcaga aggtaagcca gctaataacg
     3961 acgaagcact tgctcttatc atgccttctg gtgaaacact tgctgatgct tatgtcaatg
     4021 caacagctac aatcggtgaa aaaatctcat tccgtcgctt tgccctagtt gaaaaaactg
     4081 atgaccaaca ctttggcgct taccaacaca atggcggccg tattggcgtt atcactgttg
     4141 ttgaaggcgg agacgaagca cttgccaagc aagtatcaat gcacgtcgca gctatgaagc
     4201 caactgtttt atcatacact gagcttgacc cacaatttat caaggacgag ttggcacaat
     4261 tgaaccacgc tattgagctt gacaatgaat cacgtgcaat ggttaacaag ccagcacttc
     4321 cattcttgaa atatggttca aaggctcaat tatcagctga cgtgattgcg caagctgaag
     4381 aagacatcaa ggctgagctt gctgctgaag gtaagcctga aaagatctgg gacaaaatta
     4441 tcccaggtaa gatggatcgc ttcatgcttg ataacactaa ggttgaccaa gcctatactc
     4501 ttcttgctca ggtttacatc atggacgaca gcaaaacggt tgaagcatac cttgactcag
     4561 tcaatgctaa agcgattagc tttgctcgct ttgaagtcgg tgaaggtatt gagaaaaaag
     4621 ctaacgactt tgaatcagag gttgctgcta caatggcagc tgcgcttaac aactagtcta
     4681 atcataagtc ataagattga ggacagcttt taagagctat cttcaatctt tttttacgcc
     4741 taaaaaaaga gcttttcgag cctatccaac acaaaaagac taagagaagc atgccttcct
     4801 ccacaagcta gactatacgt tctaacgata ggagggccgt acaaagcctc ttagtctttt
     4861 tttaatgagc aatgattacc aaataatcac acgatcctct ggagcacgcc acattggatc
     4921 accttcttta atgttaaatt cttggtggaa ttcatcaaag tttgtcaagg tcacattagt
     4981 acgccattga ccaggtgcgt ggacgtcaat acttgccatc atttgcatga attcctcacg
     5041 cgccttcata cgccagatgg tggcaaagtt gataaagaaa tctctggcag aaaaatctgg
     5101 ctctgactga gctgcctcta aggcacaggc aacaccacct aggtcagcaa cattttcaga
     5161 cactgttaat ttaccattga ctttagcacc ataggagtca aggccatcaa attgctctac
     5221 aattttatcg gtacgctcct tgaaggcggc ataatcctcg tctgtccacc aattctttag
     5281 gctaccatgc tcatcaaagg aagcaccgtt ggtatcaaag gcatgcgaaa tttcatgagc
     5341 aataacagca ccgataccac cataattagc tgatgagctt tgactcaacg aataaaacgg
     5401 cgcctgcaga atagctgctg ggaacacaat ttggttttgc tgtgggtcat aataagcatt
     5461 aaccatgttg gcaggcatgt gccattcact acgatccaca ggcttattcc acttgctcca
     5521 tgaatgagca attgaaattt tggctaaatt ctgagcattt tcaacaagtg atagcttatc
     5581 atcgatgacc tttttagcat aggtttctgg taatttttcc ggatagccaa tgtgtggggt
     5641 gataacattt agctttgtaa tggctttctc acgtgttgct ggtgcaagcc aatccgcagt
     5701 ttcaagacga gatttataaa cctcaatcat cttagctacc ttgtgttcaa catcagcctt
     5761 agcctctggt gaaaattttt caccagcata ccaaagccca agagcttgat taaatggtcc
     5821 ttgtgctaag taataggctg cttttttctt gtccatagcc tgtggagttc ctgacaaggc
     5881 acgactgtaa actcctgata gcacacgaat ctcgtcagtc aaataagcat gataagcacc
     5941 tgctgctgta agcactagcc aggcttttag cagctcccaa ttcttctcag aataatagtc
     6001 agctgcaaat tctgtccaga accgctcctc tggcacaaca accttgtctg gtacttcacc
     6061 taaaatcaca gtaaatatat tatctaaagg caattctggc actagcttgg taaactcggc
     6121 ccagtcataa gggtggtaaa gcttggcata ctctgaatat tcctcacgag aaaggacata
     6181 atctgccagc tgtttatcaa gcgtgataac cttatccagc aagtccttaa cctcttcatg
     6241 tgaaaagcca aatttaggca atagctcctc ttgcatgcca cgccagatag caagcagctc
     6301 tttgcctttg tcattgtctt tggcatagta agtggtatct ggcaggataa gacctggtgc
     6361 ctctgcccaa aggacattta actgagcatt cataaagtct ggtgctacac taaatggaaa
     6421 ctgatttggt tttccattta gctcataatc agccaccttg ctagcaaact cggcaaaaga
     6481 tcctaaggcc ttgtattctt caattaagtc caaggctggc gctacgccca cctgatcacg
     6541 cttgtcataa tctgcaacca agcggtgaaa cttgacaaag ttttctaata tagcgtcatt
     6601 gggaacatgc tcaccagcca accaagcatc tgttgtggtc agcattaagt cctcaatctc
     6661 atctgctagg tctgaaaagc cccctgtacg aggcttatcg tctgggataa cagctgtttc
     6721 tgcccattga ccattgacgg cttgataaaa atcttcttga tatgttgtca tgaattgctc
     6781 cttttttaaa ttaaaccatt atgttaggac tagcttttac tcctcataat gtaatctctt
     6841 acattttacc aaaaaatcgt tcaaaatact cgttttatat taactttctg ttcaaaaata
     6901 agctcattct tcgtatcgca tggcatagat agtaaacgct tagctgcttt ggtcctttta
     6961 tcagtaagat taatcataaa aactgaacaa tcactaagaa atcaaacgat tcttctccag
     7021 cttcatgaaa acagccctca caatatgcca aaaactcagc agtaatagca aaaggcccta
     7081 tcagtcctga caaaagaatt gcaccccaaa ggtgaagata aaacctaaag cttaagaact
     7141 ttttctatga cattaaaatt agaaggtgaa atcaagagtt atcaatcatt atttcacgcc
     7201 tacagagtga aagggactga aagcgcataa ctaaaaggac tgaaccctgt ttcatacaaa
     7261 gctcaatcct aatctataag gtccagcttt ttgggtgtgg tacacctgat aggctttttt
     7321 agctaatctg ccgctaaaat cctcaaaacc tgctgctcaa tagctgctgg cgtcagctgg
     7381 tattcctcta atagataatc catctgtccg acctgaccga aacgttcgtc cacccccata
     7441 cggtaaactg gagtattact ttcctgagcc agtagctcac agatagcact cccaagccca
     7501 ccgatacgat tatgattttc aacggttaga acaggactgc ctgtaagtag accctttagc
     7561 tcatcggcca gtggctttac cctgaaaaca tcaatcacac cgatagagta gccctgctct
     7621 gccattttat cggctacctc taagcacctt ttgaccatga tccctgagca agccagcaca
     7681 aggtcttttc cttgacgcaa taggcaatag ccattagaaa agtcctcatg cccttgataa
     7741 atagcctctg gctttttacg aatggttcga atgtatttta ggccatcgag tgatagggtt
     7801 tcctttaaaa cagctttaaa ttgaacgtca tcactgacct cataaacaat agcccttgga
     7861 atcaggcgca gcagtcccag atcctcaaag ggcatatggg tgccgccatt catttccgca
     7921 ctaactccgg catcagagcc aataaccgtt gcgcctagct gggcataggc taatgaaaga
     7981 aacagctgat caaacacacg acgtgaggca aagggaccaa aggtgtgtag gtaaggctta
     8041 tagcctttaa tcgccaggcc tgctgccaga ccgaccattt ctgcttccat aatgcctaca
     8101 ttaatatagc gcttgccaaa cacctgatcc aaatggttgg tggccattga gcttgataaa
     8161 tctgcctcta agacgactac ctcagggtgc tcttggttgg ctgcaatgag gaaatctcgg
     8221 taaacatgac gcatttcttg acttgctcga gtcatcttgt cacctccaaa ctagctcgta
     8281 gctttctgac agcggcagca agcatctcct tttcggctgc tgttggtctt agatggtggt
     8341 tagctgccat tgactctagc tggctaacac cctgaccctt gacggtatct aagacgatac
     8401 acttgggctt atgacttgat gacgcctgca aagccctgat ggcttcaaaa atagcctgaa
     8461 catccctacc atctacacgt aagctttcaa agccaaatgc cgtaaacttt tcaacaaaat
     8521 cacctggacg acagattgcc tcggttgttc catctaattg cttcttattg tcatcaacaa
     8581 agacaatgaa atgacttagc tgctggtgtg ccgcaagctg gatagcctcc cagcattggc
     8641 cctcgtttaa ttccccatca ccaacgattg cataggtata atgtggtgac tgctcaagcg
     8701 cttgagcata ggcaatgccc gttgctacgc taattccctg accaagagag cctgtcgtca
     8761 tgtcaatacc aggcgttaac agacgatctg ggtgcgaggg cagacttgtt ccattggtat
     8821 taagagactg taaaaaggcc ttatcaaaaa acccctttaa gtagagagtg ctatagaggg
     8881 caggacccgc atgtcccttt gataacacca gataatctct atctgactgg acaaagagct
     8941 ctggtgtcat gggcatgatt tctccataaa gcacagccag caattctaca atagacaagc
     9001 taccgccata atgaccaaag ccaagatgat taagagtctc caaggtattt agacgaatct
     9061 ctgctgcgaa tcgcttcaca tctgttagag gctcatcact caaaaccatg cttattcctc
     9121 cttagctact gattttccaa caacagaaag cccaacaagt ccagctaata tcacaaaaat
     9181 accaatcaca atagctgtca caccacctat gctgttaagt gttcctagta aaatacctga
     9241 taagccaaaa tcggcatctg agaaggttga gccctcaaag cccaagccgc ctaaaacagg
     9301 catcaagaaa atcggaagat agctaataag aacaccctgt aaaaaggctc ccacagttgc
     9361 accgcgcaca cctccagaag cattcccaat aacaccagct gtggcaccac agaagaaatg
     9421 aggcacaacg ccaggtaaaa tcactgtcgt tccacttacg atcatcacag ccatgctcac
     9481 aaggccacca acaaagctag aaacaaagcc aatcagcact gcattggggg cataaggata
     9541 ggcaatcggg caatccaagg ccggcttaga atgtggcact aatttttcag aaatgccctt
     9601 gaaggctgga acaatttcac ccagaatcaa acgaacacca gctaaaatca caaagacgcc
     9661 tgcagcaaac tgtcctgcca actgcaaggc aaagaccaag ccatgtgtgc cagaggataa
     9721 ttccttacta atccaagtag gaccagcaaa aatagctaca atcaaataaa tgattgccat
     9781 tgataaggta atgcttactg tactatcacg caaaaaagca aggctctttg gaaaatcaat
     9841 gtcctctgtt gacttggttt tgtctccaac aagacctcct acaaaaccgc ttaaccaata
     9901 accaagagag ctaaaatgcc ccaaagcgac cttatcgtta ccagtcagct ggatcatata
     9961 ccgttgcaca agagccggtg aaacactcat gataatccct aaggccagcc caccaaacac
    10021 aatcaaggac actgacgtca agcctgcaac agacataatc acagcaatca tacaggccat
    10081 gtaaagtgtg tgatgccctg tcaagaagat atacttaaat cgggtaaagc gagcaatcaa
    10141 aatattaaag atcattcctg taaacataat cagagctgtc gctgacccat aggtcgtcaa
    10201 agcaactgca acaatagcct cattatttgg cacaacacca gacagatgaa aggcatgctc
    10261 aaacatcgtt ccaaaagggt tgagtgagcc ttgcacgata cctgcaccac ctgaaaccac
    10321 taaaaaccca acaaaggtct taatgcctcc cttaacaatg tcaggagcag gctttttttg
    10381 aagtaagaga ccaacaatag caatcaaggc aaccaaaata gctggtgtgc taacaatatc
    10441 aagtaaaaat gtcatcttat cctccttcta aacaagcccc ttttcctggc aaatagcctt
    10501 taccagacta gtcaattcgt ccatatcaat gatactattt aaaatcctca catctcccag
    10561 atgctctgcc gagtctgcca aatcacgccc aacaatccac acatctgccg ctgtgggatc
    10621 cgcgccacca agatcataat gctccacctc aacaccggtt actcccaagt cctttaatac
    10681 ggattcgata ttcatctgaa ccataaagct agaccctaag cctgaaccac aggctgtacc
    10741 aattcttaat gccattttat gcctcctctg caataatagt tttaatatcc tcaaatgatt
    10801 tagacgcaag taaagccttg acctgctcat tgtctcttaa aatggtcgtc agccgagaca
    10861 gggcctttag atgtgtttca ttatcaatag cagcaataca aattaacaaa cgaatctcct
    10921 gcttaggatc atctaacaaa taaatcgggt gctctaaaac aagcatcgac atacctacct
    10981 gattcacacc atcctctggc ctcgcatgtg ggatagcaat ccccttacct agattaataa
    11041 aagtaccaaa ctcctcaacc ttagcaatca tagcctccgg gtagctcgct tgaatctgcc
    11101 cactctctaa caagggctga gccgccaaat aaatagcctc tctccacccc aattgctctg
    11161 aggttgattg ataggttttc ttggtaatta agtcttgtaa cactggtcga atatcctttc
    11221 ttttcacacc ttgtcttaaa tattgctgca aagcaaagcg cagcttttct ttttgatgaa
    11281 tgaccgcata tgagctgata agatggagca gctcttcaac ctctagccga tagccaatat
    11341 ctggaaaatc acgattaacc aagctgacca gctgaaaagc ctgctcatca gtcattatca
    11401 tagggactaa ataaaagggc ttatcagtct ctaatcgtat cgttgaaaaa accaaatcat
    11461 agccgctctt atctaattgc ccaagctgat caagccttga aagcccccga aaagcaatat
    11521 caggaaataa aagctttaaa tgctccttga tcattaaaga agaactaaca ccattaggac
    11581 agacaatcac agcctgatag gcttgacgat gaaaatctct tccctgctgc tttaaatagc
    11641 ctccaaaatg aagaacaaaa taagcaattt cactatctgg tataggacta cccagctcct
    11701 tggctaaagg ctccagagac tgctttacca agtcaaaaag ctcagaataa ctatccttaa
    11761 tccgcaaggt ataatcatta tcacttggca aaccatagcg caaacggtaa taggctggaa
    11821 tcaaatgcct tttcaaattc tccttgagct gatctgcctg actaaagctt agtaaagcaa
    11881 ccccctgcat ttgatcaaca atcgcaacgg ttagtgattc aaagaaatca tcaccaacag
    11941 taccctcacc ctcaaagcag cccgctaaca gcaattgaaa ataggcctca tcagcttcaa
    12001 atagctgata cttaagagac aattgctgca ttatttctgc caccaaaagg gccgttagct
    12061 gatccagctg ctcagaaacc actacctgtc tttgcttgac cctatcaacc cgtctttggt
    12121 aacgacataa aataaagatg acagcgtaca aacagacctg cagacgatca aggatcggag
    12181 acatctgaaa ggtctgataa aaatggctca cacgtttttc aagcgcttca aacgacacct
    12241 gatagtgcca agaagccaaa atatagtcca aggcccacaa gccaatagga gatttaagca
    12301 aagtagcaat cattactaaa gccaaccggt gcttattaat ctcatcacca actaagatat
    12361 agccgcttgc tctggtatac tttaattcca agtcaacatc tgccagcttc tgccgcaagg
    12421 ccttaatatc tgtcaaggct gtgttcttgc tgacctttaa aaagtcctga taatgactat
    12481 ttgaaacaaa atccctgcgg caaaaggtat acagatagat aagattgatc cgctctgcct
    12541 gagaaagata aacctgctca gcattaatca acgtaaacaa atgatctgac tcagccttaa
    12601 gctgctgact gatccgatag ccagaccttg ttgcatctag ctctgagagc tcatgctgag
    12661 ccaaaaactc attcagctca tcaatacggt ccttaatctc tctaatggtg aattttgtct
    12721 taacactcag ctcgtaaagt gataagtctt gataagtcat caacgtcatc aaaatgacaa
    12781 ctgctttgct atcaaccatt tgatttcctt tctaaattca ttctatcgaa aacggttaca
    12841 ataaactagt ccccattggg cacaatttct tatccaacat catcaacagc ccttgggctc
    12901 aagatgccaa tctaaacagg ctaccagctc ctcctaacta tcaataaaga gcaaacaagc
    12961 ccatctctgc cgctaagcaa ttgtccccat gatttcctaa gtccaagcca aagctaaagc
    13021 tctttggagt aataaccgtc aaaaatgttc caaataatca aaaaaactga ttgacctcat
    13081 cagcatgtga taactctaga tataagccta aaacaagatt acagacttaa tagttaactg
    13141 gtaatctttt attataccac gaaaacggtt accaaaaaag acttgtgttt tattatttta
    13201 ataatataat gaaactataa gatatcttat taaatgacaa ataactacca tcttggttag
    13261 aaaggagtaa agctaattaa cccttagtag atcaccatcg ttttcagaaa ggaaattcaa
    13321 aatgaaaaaa gtaaaacaat tgatcatcgc aatgatagcg tccttattac tcattgctaa
    13381 cactgtacct tccattgtat atgctagtga agtgactaaa attcaacagg aagaaaaagt
    13441 aattgaagaa aaattatcac aacctctaga aatttcaaaa agtgagttag atacattaat
    13501 ccaagagaaa aaagctcttt atccaaattt aacagaacaa gaaatgcgtg aaattgcgta
    13561 taaagccatg agtccataca cttttagagc tagtgtatgg gacgggcaag gagtaacctt
    13621 agatgaattc gcttgggctt ttgatgttat tgtaggcggg ttaattagtg gatatgcaac
    13681 catcggaaag tacgttgcca aacatggagt agctgccgct cgagctgtac ttagccgagc
    13741 tgcaaaagct gcagctcaac gacttggtgt actaaccgga tttatttccg gtttacttag
    13801 agctgcattc tcagtaataa acatttacta taatgtcgga tatgccctag cacaatatgt
    13861 cgatgctcga gattatcacc caaataacgg tcgtataaat gcgtgggctt aagaactata
    13921 tttgttattt tattattgta atgtcagttt atacagcaat agcatattgt ttcaatcgct
    13981 tatccttatc atttactcca aaactagttt tctattcggc cataaccacc tatacttttt
    14041 acataacaaa aaataaagac tga
//
LOCUS       DARYXW010000052        13789 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.052, whole genome shotgun sequence.
ACCESSION   DARYXW010000052 DARYXW010000000
VERSION     DARYXW010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13789)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13789)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13789
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.052"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            <1..129
                     /locus_tag="TV191_001269"
     CDS             <1..129
                     /locus_tag="TV191_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase"
                     /protein_id="HEL1507782.1"
                     /translation="RKCGIELRENYNKSKKDKQVIPQCTPEKEKAIMDALRHFKMI"
     gene            149..430
                     /locus_tag="TV191_001270"
     CDS             149..430
                     /locus_tag="TV191_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507783.1"
                     /translation="MRWIIKIILFPFSLLLSVLTAFLTFILGIGTTILYFLMLMCIVA
                     AIGSFMQKDISLGIEALVLGFLLSPYGIPMVGAAVIAFFKGINEAIKSI"
     gene            517..1296
                     /locus_tag="TV191_001271"
     CDS             517..1296
                     /locus_tag="TV191_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEL1507784.1"
                     /translation="MDFDYFYNREAERFNFLKVPEILVDGEEFKGLSAEAIILYSMLL
                     KRTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDSKKGIGLIERVR
                     LGLGKPNIIYVKDFMSIFQVKEDDLQKLKNFTSEVKDFNLRSKENELQEVKNLDSNYI
                     ENNKSKYSKREYNFSENGLGTFQNVFLAAEDISDLQIIMNSQLDNYIERLSAYIKSTG
                     KTYKDHKATILSWFYKDQGRGKEVKTSNIPTWEEYDKGEHL"
     gene            1293..2067
                     /locus_tag="TV191_001272"
                     /pseudo
     CDS             1293..2067
                     /locus_tag="TV191_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588832.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            2064..2549
                     /locus_tag="TV191_001273"
     CDS             2064..2549
                     /locus_tag="TV191_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009346332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HEL1507785.1"
                     /translation="MINEEIARKTLNMEVRAAKVTGKLILNLLKKLMKEAEKLGGLEK
                     LVNANGNEVKLKDMVKKGQLEEIPVEEAELKELKKELNRYGVKFSVMKDKETGKYSVF
                     FQAKDMKVMDKAFKHALAQSEKKTERKESIHKNIEKFKEMAKNSVSKDKIKNKQKEQS
                     L"
     gene            2546..4017
                     /locus_tag="TV191_001274"
                     /pseudo
     CDS             2546..4017
                     /locus_tag="TV191_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001899253.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
     gene            3971..4327
                     /locus_tag="TV191_001275"
     CDS             3971..4327
                     /locus_tag="TV191_001275"
                     /inference="COORDINATES: protein motif:HMM:NF014581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="HEL1507786.1"
                     /translation="MERKKTLKELSETLGKETIDLYNTSETRSNQKSFGLNYQKTGKE
                     LMSQDEITVMDGGKCIFQLRGVRPFLSDKYDITKHKNYKLLEDYDKKNLFDIESYMKR
                     KGKAKLNRETVITRMQ"
     gene            4491..4802
                     /locus_tag="TV191_001276"
     CDS             4491..4802
                     /locus_tag="TV191_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL1507787.1"
                     /translation="MKQEMININANLVAEPTFSSFEKEGKEVEVVNFTLVKKYGKGKE
                     YINCAAYGEKADKAKDFEKGDLIHVFGYFKKREKEGKTYKNFVVKSYNKIEKKEENEE
                     E"
     gene            4806..5021
                     /locus_tag="TV191_001277"
     CDS             4806..5021
                     /locus_tag="TV191_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002838961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HEL1507788.1"
                     /translation="MEFFAQAVNVLKILVMAVGAGLGAWGVINLMEGYGNDNPGAKSQ
                     GIKQLMAGGGIVLIGLKLIPLLANVLR"
     gene            5041..5907
                     /locus_tag="TV191_001278"
                     /pseudo
     CDS             5041..5907
                     /locus_tag="TV191_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466911.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            5927..6190
                     /locus_tag="TV191_001279"
     CDS             5927..6190
                     /locus_tag="TV191_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1507789.1"
                     /translation="MNKRKTVFTAVVMVAGIMAVIDRIRLHNKAAELEERTQDIGRCH
                     NDFCLMQQRYNKNTDEQLAIIQDEIGSVYEHFEEFSKGKEDGR"
     gene            6194..6583
                     /locus_tag="TV191_001280"
     CDS             6194..6583
                     /locus_tag="TV191_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HEL1507790.1"
                     /translation="MAYVPIPKDLKKVKTKVAFNLTKRQLIGFTIAGLVGIPVYLFMR
                     KVVPNDIAFIFLIVSTLPIFFITLFEKDGLTFEKYFKHIYLHKFYQPAKRVRKEVYLE
                     QEKKNSATKVRRKQKGIKKGEKGLKAK"
     gene            6495..8924
                     /locus_tag="TV191_001281"
     CDS             6495..8924
                     /locus_tag="TV191_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEL1507791.1"
                     /translation="MNKKRKIQQLKLEENKKALKKERKDLKQSKGKSNKEKSGLLDLI
                     FRKEQKRYTVEDTIPYLRLLKSGICQLDEKHFSKSIAFQDINYQLALDEDRDLIFNQF
                     ANFLNSFDPSIAIEFSYINQLGRNEEMKSAIQIPDKGDGFDDIRLEFREMLKSQIVKG
                     NNGLKKSKYVTFTVEADNLEQATSKLERLDIDILSNLKSMGVRAESLTVEERLKILHD
                     ILNPNKTFEFSYKDLKKKESTKTYIVPDEFNFMPSRYFKFGKFIGATSHFQILASELS
                     DRMLSEFLDIDDNINISFHIKAIDQSEAIKMVKRKNTDIDKMRIEENKKAVRSGYDMD
                     ILPSDLITYGEDVKSLLKDLQTRDERMFVVSIVFMNFARTVQKLDNTIAQISSIANKH
                     NCKLKRLDHTQEQGLVSVLPLGVNKIEIDRGLTSSSTAVFMPFTTEELFINSSNSLYY
                     GLNALSHNLIMADRKKLKNPNGLILGTPGSGKSFSAKREMANAILVTDDDVIICDPEG
                     EYGNLVRQFNGEVIKVSSKSKDYLNPLDINMNYGDGDAPLKDKANFIMSMLELVVGGS
                     GLTAEEKSVIDRCLPKIYERYFENPTYDNMPILQDLYDMLKGQEEKVGKKLATEMEIY
                     VSGSLNVFNHRSNVDLNKKLLCFDIKELGSQLKKIGMLVIQDQVWNKVSQNRGNKATR
                     YYIDEFHLLLKDEQTASYSVEIWKRFRKWGGIPTGITQNVKDLLMSKEIENIFDNTDF
                     VLMLNQASGDREILARKLKISLPQLRYVTNSNEGEGLLFFGNTIVPFLDKFPKDTILY
                     QKMTTKPEEVR"
     gene            8928..11051
                     /locus_tag="TV191_001282"
     CDS             8928..11051
                     /locus_tag="TV191_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1507792.1"
                     /translation="MDGKLKKDFRERHKASLEREMLKAETSSIPEESKLKHNDDYRGK
                     IVHDKDRFQDKVHEKISKVRSENEQIEGTSKRNAKYRASDKGSVNEAGKADYDTEVKN
                     GKIYDSLGQDLDNDGIIDRYDNDFRDSDYFESTYDVEDNLPQKEKSLENPSKNHKAQK
                     NKYKRKNYSESLYTRKKDDVPKENKPEDKKAGKDVAGEKEHSSLSKDQKKKLKKDMVK
                     VSALSGLAKGSETVRDYLSHGSDENKGVEAGEKTADASSKLIHGIKRYSDKKRAKKGY
                     ELTNKDYKIRKRKSKLEFRDAKEELKKTDEYKRASAYKRFQKKNQVKAAISRENKSRL
                     RDRIKEGLIGTLKSSKDMIIRKAKGLMLIFVGIIILGNFVINFAGTGMTGFMNSTNSV
                     LTTSYLSKPNVLSEINQKFSAMESELQSEVDHVEENYPGYDEYILNNTEYIGHNVHEL
                     LSYITSRCGEVKSVSEVETILKELFESMYDLEYREEIEIRYRTVTETYTDEDGNEYTE
                     SHEEPYEYKKLIVTLHKKEMDSIIRRVFKDYPDNLKHYEALFLAQGNMGEAFRNSDLI
                     SANGGVGGGKEYEASSEVQKKIVNAAYITPSPGAGWCAMWVSQVYQNAGLGYIGGNAN
                     DMYRNYTFTSDRSKLKVGMLVAVESSSSGSTAGLTYGHVGIYIGDGKVIDNIGYIRVT
                     TLDDWIATFCKHHPVGFGFPPNVNR"
     gene            11064..11303
                     /locus_tag="TV191_001283"
     CDS             11064..11303
                     /locus_tag="TV191_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1507793.1"
                     /translation="MKKELTAVKNRIKKLKDKKALIDEELEPLFIREEELENEEIIMI
                     CRKNNITISDLMTKVNREKAELKKERTNENQFEKE"
     gene            11278..12825
                     /locus_tag="TV191_001284"
     CDS             11278..12825
                     /locus_tag="TV191_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HEL1507794.1"
                     /translation="MKTSLKKNNKFWTAALAVIVSISCILGLWTVVYAKEKSSDAPTK
                     NEAVQTEVEVNVKYIFEDEKVFKEEKIKAEKGQLLDSGDLPMLPDDMKFIDEFLFYEV
                     KGDGNDEIIRKVAKTEVKDKETQTEEEKPKQDESTQTEATKTEDKGTQTELSKDDISK
                     MEKEAKELQEKFDKLNGELKDKDKQKEKIKDLEDEIDSLKEKMKKDKGNKDLSEDMKK
                     EIDKLTDKVKELEKKATETKKSSEAINSVTPISPISGIKTSSSISPQTPQTSVSSSGK
                     GSSDTVSSGNATKDTSKTEVKEKEKEVRYSNKLTAKAPANNSSQDSSMEGASSNVNTN
                     KGVASSPSKARGTVTENKDNGNKDYPIHHGDSSDNKETDQYSADARQFITFQTKNGKT
                     FHLIINHDEDSENVMLLTEVSEDDLLNMVEKKEAPKQEIVKEEPVKEEVKPEKKEEKS
                     NLGTYIILLLVVGGALGAGYYFKVVKKKEDKELEALEEEDDDFFSEAESEEETNDVDE
                     VEAEDEQ"
     gene            12921..13697
                     /locus_tag="TV191_001285"
                     /pseudo
     CDS             12921..13697
                     /locus_tag="TV191_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779853.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
BASE COUNT         5223 a         1995 c         3021 g         3550 t
ORIGIN      
        1 agaaaatgtg gaatagaact tagagagaat tacaataaat caaaaaaaga taagcaagtt
       61 attccgcagt gtacacctga gaaagaaaaa gctattatgg atgcgttaag gcactttaaa
      121 atgatttaag agaaaggaga ggtattatat gaggtggata ataaaaataa tattgtttcc
      181 attcagcttg ctacttagtg tccttactgc ctttctgaca tttatacttg gcataggaac
      241 aactattctg tatttcttaa tgctgatgtg tatagttgct gcaataggat catttatgca
      301 aaaagatata tcacttggca ttgaggcatt agtattagga tttttgttaa gtccttatgg
      361 aataccgatg gttggagcag cagttatagc attctttaaa ggaatcaatg aagcaataaa
      421 atcaatctaa aaaatttcat aaaaatggtt accaaaggcg atagagaaaa actatcgtct
      481 ttttctttgc aaatttttaa ggagggaggt gaagcgatgg actttgacta tttttataac
      541 agagaagcgg aaagatttaa tttcttaaaa gtaccggaga tattggttga tggagaagaa
      601 tttaaaggat tatccgctga agcaattatc ctttattcaa tgcttcttaa acggacagga
      661 atgtccttta agaataactg gattgataag gaaggcaggg tatttatcta tttcacagtc
      721 gaagaaatta tgaaaagaag aaatatctca aagccgactg ccataaaaac attagatgaa
      781 ttagatagta aaaaaggaat tggactgatt gaacgggtac ggcttggact tggaaagccg
      841 aatatcattt atgtcaaaga ttttatgagc atatttcagg taaaagaaga tgacttacag
      901 aagttaaaaa attttacttc agaagtaaaa gattttaacc tcagaagtaa agaaaatgaa
      961 cttcaagagg ttaagaacct tgactctaac tatatagaga ataataagag taagtatagt
     1021 aagagagaat ataattttag tgaaaacggg cttggaacat ttcaaaatgt gtttttagct
     1081 gctgaagata tatcagactt acaaatcata atgaactcac agcttgataa ttatattgag
     1141 agattatctg catatattaa aagcaccgga aagacctata aagaccataa ggcaacaatc
     1201 ctttcatggt tttataaaga tcagggaagg ggcaaagaag tgaaaacatc aaatatcccg
     1261 acatgggaag aatatgataa aggagaacac ctatgataaa agaattagaa aaagtaatga
     1321 tagaggatgt agagtattct tacgatcctg aaaaagaata tatcaaggac ggacacgcct
     1381 tttgtaaagt ttgtcatgaa agaaaagaca gaaaagtgat ggagttcttt gataacaaga
     1441 tgatatttaa gatttcttgc aaatgcgata gagatagaga ggcaagaaaa aaagaaagag
     1501 aaaagcagat ggaaatagaa cgattaaaaa agaactgctt taactctatt attcagtggt
     1561 catacacctt tgaaaattat cagggagaag aaaatcaaag tcttatcatt gcaaagaatt
     1621 ttgtaaaaga ctatgagcag atgaaaaaag aaaatatcgg actgctattt tacggctcag
     1681 taggaagtgg aaaaacctat cttgcctgct ccattgcaaa tagccttatt gaacagtatc
     1741 aaataggcgt taaaataaga aattttgcac agcttatcaa tgagctgcaa aagggaggat
     1801 ttgattttga taagaacgca tatattgaat cccttgtaaa tacttccgtt cttatcttgg
     1861 atgacttggg aatagaaaga gatacaagct atgccaaaga gcaggtatat aacattgtca
     1921 acaacaggta cttaaagcag aaaccgacta tcttcaccac taacctttcc tacgacacaa
     1981 tccaaagagg attttagaaa gattattcaa agagataaat tgaatcgaaa taaagatagg
     2041 ttactgaatg gaggtgagag aacttgatca atgaagaaat agcaagaaaa acgctgaata
     2101 tggaagtaag agctgctaaa gtaacaggaa agttaattct gaacttatta aagaaattga
     2161 tgaaagaagc agaaaaactt ggaggacttg aaaagctggt taatgctaac ggaaatgaag
     2221 taaagctaaa agatatggta aaaaagggac agcttgaaga aattcctgtt gaagaagcgg
     2281 agcttaagga actgaaaaaa gaacttaatc ggtatggtgt taagttttca gtgatgaagg
     2341 ataaggaaac aggaaaatac tctgtattct ttcaagccaa agatatgaaa gtgatggata
     2401 aagcctttaa gcacgcatta gcacagtctg aaaagaaaac ggaaaggaaa gaatctattc
     2461 acaagaatat tgagaagttt aaggaaatgg ctaagaactc tgtttccaaa gataaaatca
     2521 agaataaaca aaaggagcag agcctatgat agataaaata ttaaaggaca tcaaaggctt
     2581 atttaaggtg caggataaga caaagtttgt aaagcaaaac attccctatc ttgcattttt
     2641 ctatttagga aacatctttg cccatcatgt gagaagctat accggtggtg atgtcataga
     2701 taaaatcttt caagggatat tggagatcaa cacgatgagt tttcttccaa gtattcatcc
     2761 ggcggatatt ttaatgggca taggaatggc tgctttaatt aaatttattg tctataccaa
     2821 aggtaaaatg ctaaaaagtt tagacagggg aaagagtatg gctcagcaag atggggaaat
     2881 aagaaagata ttgagccata catggatgaa aagtttcaaa acaatatctt gcttacccag
     2941 acagaacgcc taactatgaa tggtagaccg gctaatccaa agtatgctcg taacaagaat
     3001 gtacttgtaa tcggtggatc aggaagtggt aagacaagat tttatgtaaa accgaacctt
     3061 atgcagatgc acagtagcta ttgcgtaacc gatccgaaag gaacgatagt cattgaatgt
     3121 ggcaagatgc ttgaagacaa tggatatgag ataaaaattc taaataccat aaacttcaaa
     3181 aagagcatga aatacaatcc ctttgcctat atccattctg agaaagatat actcaaatta
     3241 gtgcagacaa tcattgcaaa tacaaaaggt gagggagaaa aagcgggtga agatttttgg
     3301 gtcaaagcgg aaaaactcta ctacacagca cttatcggat atatcttcta tgaagctcca
     3361 agagaagaaa agaactttgc aacgctcctt gatatgatag acgcttcaga agtaagagaa
     3421 gatgatgaaa cctatatgaa tccaatagac agactctttg aagcacttga gaaaaaggag
     3481 cctacgcact ttgcggtcaa gcaatataaa aaatataaat tggctgcggg aaagacagca
     3541 aaatctattc ttatatcttg tggtgcaagg cttgctccat ttgatattca ggaacttaga
     3601 gatttgatga gtgaagacga acttgagctt gatacattgg gagatagaaa gacagcactc
     3661 tttgttatta tctctgatac agatgatacc tttaactttg tagtgtctat tatgtattca
     3721 cagttattta atctactttg cgataaggcg gatgatgtat atggtggcag acttcctgtt
     3781 catgtaagat gcttacttga tgagtttgca aatatcggct taattccaaa gtttgagaag
     3841 ctcatagcca caattagaag tagagaaatt tcagcgagta ttatcttaca ggcacaatct
     3901 cagctaaagg caatatataa ggataatgct gataccattg tgggtaactg tgatagtacc
     3961 ttattcttag gtggaaagga aaaaaacact aaaagagctg tccgaaacgc ttggtaaaga
     4021 aactatcgac ctttacaaca catcggaaac aaggtcaaat caaaagagct ttggacttaa
     4081 ctatcaaaaa acaggcaaag agctgatgag tcaggatgag attacggtca tggatggtgg
     4141 aaaatgtatc tttcagctta gaggtgtcag accttttctt tcagataagt acgatattac
     4201 aaagcacaag aactataagc tgcttgagga ctatgataag aaaaatttat ttgatataga
     4261 aagctacatg aaacggaaag gaaaagcaaa actgaatagg gaaacagtta ttacaagaat
     4321 gcagtaagtc tacaaaatag atttgctgct tttttatgca aaagtaagga ggcaagatga
     4381 taaggatcag aagtcccact gagtaaaaaa ctaaatagta tgagtatagc gattggaaaa
     4441 gtaatacttc cggtcgcttt ttttattgaa atgaaaagga gaaattttta atgaagcaag
     4501 aaatgattaa catcaacgcc aacttagtgg cagaacctac tttctcaagt tttgaaaaag
     4561 agggtaaaga agtagaagtt gtaaatttta cgcttgtaaa gaagtacggt aaaggcaagg
     4621 agtacatcaa ttgtgcagcc tatggagaaa aagcggataa agcaaaggac tttgaaaagg
     4681 gcgatttgat tcatgtattc ggctacttta agaagcgtga aaaagaggga aagacttaca
     4741 aaaattttgt agtgaagtca tacaacaaga ttgaaaagaa agaagaaaat gaggaggaat
     4801 aaattatgga atttttcgca caggcagtaa atgtattaaa gattttggtt atggcagtag
     4861 gagcaggact tggagcatgg ggtgtcatta acctgatgga aggttatggt aacgataatc
     4921 cgggagccaa aagtcaaggg atcaagcaat tgatggcggg aggaggtatt gtccttatcg
     4981 gacttaagct gattccactt cttgcaaatg tactcagata agaagaaaag gagagcttag
     5041 atgtttggga tattcgacaa aatagaagaa ttctttaagg agcttctact gggcggtatc
     5101 caagcaaact tagagtccat gtttcttgac atcaacgaca aggttggtgc agttgcaaca
     5161 gatgtaggaa aaactcctat ggggtggaat ggagatgtat ttacctttat taaaagcatt
     5221 aacgattcgg tcattattcc catagcggga ctaattatca cagcagtcct ttgtatcgag
     5281 cttatcaata tggttataca gaaaaataac ctacatgata atacggatac atttgaattt
     5341 ttcaagtaca tcatcaagat gtgaattgct gtatggttgg tatctcacgc ttttgaattt
     5401 tcaatggcgg tctttgatgt agcacagcat atggtaaata aggcggcagg ggtgataaac
     5461 acctctgcca ccgtttccgg agatcagata gtggcgatga tggataccct aaaagaaaag
     5521 ggacttggag agcttatcat gattctcttt gaaacctcgc tcattaaagt tgccatacag
     5581 gcaatttcca tagtgattat gcttgtggtt tacggaagga tgtttgagat ttatgtttat
     5641 tcatcggttt cagccattcc atttgccacg atgggaaaca aagaatgggg gcaaattggc
     5701 acaaattaca tcaaaggatt atttgcactt ggactacaag gactcttttt aatggtttgt
     5761 cttggaattt acgcagtatt agttaagacg attgaaataa cagatataca cacaagtacc
     5821 atgacgatac ttggttatgc ggttttgctg gggttaatga tgctaaagag cggaacactg
     5881 gccaaaagcg tattaaatgc acactaaaaa agaaaggaaa gatagtatga ataaaagaaa
     5941 aacagtattt acagcagtag taatggtcgc aggcattatg gcggtaattg atagaatcag
     6001 gcttcataac aaagctgccg aattagaaga aagaacacag gacatcggtc gctgccataa
     6061 tgatttttgc ttaatgcagc aaagatataa caagaataca gatgaacagc ttgcaattat
     6121 tcaggatgaa atcggctctg tatatgaaca ctttgaggag ttttcaaagg gtaaagaaga
     6181 tgggaggtaa gctatggcgt atgtaccaat acccaaggac ttaaagaagg tcaagacaaa
     6241 ggtagccttt aaccttacaa aaagacagct cataggattt accattgcag gacttgttgg
     6301 aatacctgtc tatttattta tgagaaaggt agtaccaaac gatatagctt tcatattcct
     6361 tatcgtgtcc acacttccaa tcttttttat cacacttttt gaaaaggacg gactgacctt
     6421 tgagaaatat tttaagcata tctaccttca taagttttat cagccggcaa agagagtgag
     6481 aaaggaggtt taccttgaac aagaaaagaa aaattcagca actaaagtta gaagaaaaca
     6541 aaaaggcatt aaaaaaggag agaaaggact taaagcaaag taagggaaag tctaacaaag
     6601 aaaagagcgg actacttgat cttatcttta gaaaagagca aaaacgctat acggtagaag
     6661 ataccattcc ctatcttaga ctcttaaaaa gcgggatatg ccagctcgat gaaaagcact
     6721 tcagtaaaag catagccttt caggacatta actatcagct tgctttagat gaagataggg
     6781 atttgatttt taatcagttt gcaaactttc taaattcctt tgatccaagc atagcgattg
     6841 agttttccta catcaatcag cttggacgaa acgaagaaat gaaatcggca attcagatac
     6901 cggataaagg ggacggattt gacgatatac gacttgagtt tagagagatg ctaaaaagtc
     6961 agattgtaaa aggaaataac ggactgaaaa aatcaaagta tgtaaccttt acagtagagg
     7021 cagacaattt agaacaggct acatcaaaac ttgaaagatt ggatatagat atattatcta
     7081 atctcaaaag catgggggta agagctgaaa gtcttacagt agaggaaagg ctaaagattc
     7141 ttcacgatat attaaatccg aataagacct ttgagttttc ctacaaagac ctgaagaaaa
     7201 aggaaagtac caaaacatat atcgtgcctg atgaatttaa ctttatgcca agcaggtatt
     7261 tcaagtttgg gaagtttatc ggagcaacaa gtcattttca aatccttgca agtgagcttt
     7321 cagaccgtat gttatcggag tttttggata ttgatgataa catcaatata tcttttcata
     7381 ttaaggcgat tgaccagtca gaagccatca agatggtaaa acgaaaaaac accgatattg
     7441 ataagatgcg aattgaggaa aacaagaaag ctgtaaggtc aggctatgac atggacattc
     7501 ttccaagtga tttaattact tacggagaag atgtaaaaag tcttttaaaa gatttacaga
     7561 caagagatga gcgtatgttt gttgtaagta ttgtctttat gaattttgca aggacagtgc
     7621 aaaagctcga taacaccata gctcagataa gctccattgc aaacaagcat aactgtaaat
     7681 tgaaaagact tgaccatacg caggaacaag gcttagtgag cgtgctgcct cttggggtaa
     7741 acaagattga aatagataga gggctaacct catcatcaac agcagtcttt atgcctttta
     7801 caacagagga gctttttatc aattcaagta atagcctata ctatggacta aacgctttaa
     7861 gccataacct gattatggcg gatcgaaaga aattaaagaa cccaaacggt ctaatcttag
     7921 gaactccggg tagtggtaag tcctttagtg ccaaaagaga gatggcaaat gcgattttag
     7981 taacggacga tgatgtgatt atctgtgatc cggagggaga gtatggaaac cttgtaagac
     8041 agtttaatgg agaagtcatt aaggtcagca gtaagtcaaa agattacctg aatccacttg
     8101 atataaatat gaactacggt gatggggacg cacctcttaa agacaaggca aacttcatta
     8161 tgtctatgct tgagcttgta gttggtggta gtggacttac agcggaagaa aagtccgtta
     8221 tagatagatg cttacctaag atttacgaaa ggtactttga aaatccgact tatgacaata
     8281 tgcctatact tcaagaccta tacgatatgt taaaagggca ggaagaaaag gtagggaaaa
     8341 agctggcaac agagatggaa atttatgttt caggttctct taatgtcttt aatcacaggt
     8401 caaatgtgga cttaaataag aagctacttt gttttgatat taaggagctt ggaagtcaat
     8461 taaagaaaat aggtatgctt gttatacagg atcaggtgtg gaataaggta tcgcaaaaca
     8521 gaggaaacaa ggctacaagg tactatatag atgagtttca cttgctgtta aaagatgagc
     8581 agacagcttc atattcggta gagatttgga agcgttttag aaaatgggga ggaatcccga
     8641 ctggtatcac gcaaaatgtc aaagacctac ttatgagtaa ggaaattgaa aatatctttg
     8701 ataatacgga ctttgtctta atgttaaatc aggcttcggg agatagggaa atacttgcaa
     8761 ggaaacttaa aatctcactt ccgcagctta gatatgttac gaactccaat gagggcgagg
     8821 gactactttt ctttggaaat accattgtgc ctttccttga taagtttccg aaagatacaa
     8881 ttctttatca gaagatgact accaagcctg aagaagtgag gtagcttatg gatgggaagc
     8941 tgaaaaaaga ttttagagaa aggcataagg caagccttga aagggagatg cttaaagctg
     9001 aaacaagctc tatacctgaa gaaagtaagc taaagcataa cgatgattac agaggaaaaa
     9061 ttgtccatga caaagataga tttcaggaca aggttcatga gaagataagc aaggtaagat
     9121 ctgaaaatga gcagatagag gggacttcta aaagaaatgc aaagtatagg gcttctgata
     9181 agggaagtgt aaatgaagca ggaaaggctg actatgatac tgaggtaaag aacgggaaaa
     9241 tctatgattc tttaggacaa gaccttgata atgatggaat catagacaga tacgataatg
     9301 attttaggga cagcgactac tttgaatcaa cctatgatgt agaggataat ctacctcaaa
     9361 aagaaaaatc attagaaaat ccctctaaaa atcataaggc tcaaaagaat aagtataaaa
     9421 ggaaaaacta ttccgaaagc ctctatacaa gaaaaaagga cgatgtacca aaagagaata
     9481 agcctgaaga taaaaaggca gggaaagatg ttgcgggcga aaaagaacat agcagtcttt
     9541 caaaagacca aaagaaaaag ctgaagaaag atatggtaaa agtatctgcc ctgtcaggac
     9601 ttgccaaagg aagtgaaacc gtaagagatt acctttctca tggaagtgat gaaaataaag
     9661 gcgtagaagc gggagaaaaa acagccgatg caagttcaaa actcattcat ggtataaaga
     9721 gatactcaga taagaaaaga gctaaaaaag gatatgagct tacaaataag gactataaaa
     9781 tcagaaagcg taaatccaag ttagagtttc gtgatgccaa agaggaactg aaaaagacag
     9841 atgagtataa aagagcaagt gcctataaaa gatttcaaaa gaaaaatcag gtaaaggcag
     9901 cgatttctcg tgagaataag tcaagactca gagatcggat taaagaggga cttatcggaa
     9961 cactgaaaag ctcaaaggat atgattatcc gaaaagccaa aggactaatg cttatcttcg
    10021 taggtatcat catcttagga aattttgtga ttaactttgc aggaacaggc atgacaggct
    10081 ttatgaactc tacaaactct gttcttacaa caagctattt atcaaagcca aatgttctaa
    10141 gtgaaatcaa tcagaagttt tctgctatgg agagtgagct tcaaagtgaa gtggatcatg
    10201 tagaagagaa ttatcccgga tatgatgagt atatcttaaa caacacagag tatatcggtc
    10261 ataatgtcca tgagctttta tcctacatta catcaaggtg cggagaggta aagagtgtat
    10321 cggaagtaga aaccatatta aaagaattgt ttgagtccat gtatgacctt gaatacaggg
    10381 aagaaattga aatcagatac aggacagtta cagaaaccta taccgatgaa gatggcaatg
    10441 aatataccga aagccatgaa gagccttatg aatataagaa gctcattgta acgcttcata
    10501 aaaaagagat ggacagcatt atccgaaggg tctttaaaga ctatcccgat aatttaaagc
    10561 actatgaagc cttattcctt gctcaaggaa atatgggaga agcctttaga aattctgacc
    10621 ttatcagtgc taatggcggt gtaggtggtg ggaaagagta tgaggcatct tcggaagtac
    10681 aaaagaagat tgttaatgct gcatatatca ctccatctcc gggtgcaggc tggtgtgcca
    10741 tgtgggtatc gcaagtttac caaaatgcgg gacttggata tatcggagga aatgctaatg
    10801 atatgtatcg aaactatacc tttacatccg ataggtcaaa gctcaaggta ggaatgcttg
    10861 tagcggtaga aagcagcagt agcggaagca cagcaggact tacctatggt catgtcggaa
    10921 tctatatcgg agacggcaag gttattgata atatcggtta tataagagta actactttag
    10981 atgattggat tgcgactttt tgtaaacacc atccggtagg ctttggtttt ccaccaaatg
    11041 taaacagata aggagggaac aatatgaaaa aagaactgac agcagtaaaa aacagaataa
    11101 aaaagttaaa ggataaaaag gctctgattg atgaagaatt ggagccttta tttattcgtg
    11161 aagaagaact tgaaaatgaa gaaatcatca tgatttgcag aaagaacaac atcacaattt
    11221 ctgatttaat gacaaaggta aacagagaaa aagcagaact gaaaaaggag aggacaaatg
    11281 aaaaccagtt tgaaaaagaa taataagttt tggacagcag cacttgcagt aattgtaagt
    11341 attagctgca ttttaggact ttggacggtt gtttacgcca aggagaaaag ctctgacgct
    11401 cctacaaaaa acgaagctgt ccaaacggaa gttgaagtaa atgtaaagta tatctttgaa
    11461 gatgaaaagg tatttaagga agaaaagatt aaggcagaga aaggacagct tcttgatagt
    11521 ggcgatcttc caatgctccc tgatgatatg aaatttattg atgaattcct gttttatgaa
    11581 gtaaagggag atggaaatga tgaaattatc cgtaaggtag caaagactga ggttaaggat
    11641 aaggaaacgc aaacggaaga agaaaaacca aagcaggacg aaagcacgca aacagaagct
    11701 acaaaaacgg aggataaagg cacacagaca gagctttcta aagacgatat ttctaagatg
    11761 gaaaaagagg ctaaagagct tcaagaaaaa tttgataagt taaatggtga gcttaaagac
    11821 aaggataagc agaaagaaaa aatcaaagac cttgaagatg aaattgacag cctgaaagag
    11881 aaaatgaaga aagataaagg aaataaggac ttatcagaag atatgaaaaa ggaaatagat
    11941 aagctgactg ataaggtgaa agagcttgag aaaaaggcaa ctgaaacaaa gaaatcttct
    12001 gaagcaataa attctgttac accgattagt cctatttccg gaattaagac aagctcaagc
    12061 atttctcccc aaacaccaca gacttctgta agtagttccg gtaaaggctc atctgatacg
    12121 gtgagttcag ggaatgctac aaaggataca agcaaaacag aagtaaagga gaaagaaaag
    12181 gaagttcgct attctaataa attgacagca aaagcacctg ctaataacag cagtcaagat
    12241 tcgtcaatgg agggggcaag tagtaatgta aataccaata agggagtagc ttcatctccg
    12301 tcaaaggcaa gaggaactgt tacagaaaat aaagataatg gaaataaaga ttatccgatt
    12361 catcatgggg atagcagcga taataaagaa acggatcaat attccgctga tgcaagacag
    12421 tttattacct ttcaaactaa aaacggtaag acctttcatc tcatcatcaa ccacgatgag
    12481 gatagtgaga atgtcatgct tcttacagaa gtatccgaag atgatttgct taacatggta
    12541 gagaaaaaag aagctccaaa gcaggagatt gtaaaagaag aacctgttaa ggaagaagta
    12601 aagcctgaga aaaaagaaga aaagagtaat ttaggaacat atattattct gcttcttgtt
    12661 gtaggcggag cattgggagc aggatactac tttaaggttg taaaaaagaa agaagataag
    12721 gagcttgaag cattagagga agaagatgat gatttctttt ctgaagctga aagcgaggaa
    12781 gaaacaaatg atgtagatga agtagaagcg gaagatgagc agtaatgctg caccaaaaaa
    12841 atacagtatt tggtgcaaat gcagggcggg agaataaaat ctttcgccct tttatattga
    12901 aaacaggagg cagtacagaa atgaagttag tcattgcaga aaaaccaagt gtagcattaa
    12961 gtattgcaaa agtacttgga gcaaataaaa agaaagacgg atattatgag ggaaatggat
    13021 acaaagtatc ttggtgtgtt ggacacttaa ttcaaatggc aaatccggat gtttatgatg
    13081 aaaagtatgc caagtggaat atggttgatt taccgattat ccccaaggac tataagtatg
    13141 aagtggcaaa gtcaaccaag aaacaattta acatccttaa aaagttgatg aacgacaaag
    13201 aaattgatac ggttatcaat gcgtgcgatg caggtagaga aggggagagc atttttagac
    13261 ttgtatataa tcaagtgaat tgtaaaaaga agatgaaaca cctttggatt tcatctatgg
    13321 aagatactgc cattaaagat ggctttgatc atctaaaaga cggaaaagat tacgataatc
    13381 tctttgagtc ggcacaggca agagctatcg ctgactggct tgtcggaatg aatatcagca
    13441 ggctctattc ttgtctgtat aagcaaaatt acagtgttgg cagagtacaa acaccgactc
    13501 ttgctatgat cgtaaaaaga gatgatgaga tagcaaactt taagaaagaa aaatattata
    13561 cggtagagct ttctacaaat agctttacac tttcaacaga tagaattgat gatgaaatag
    13621 cagcagagca gctcttaact ttagtgggca ataagattga aataactgat gtcattcaaa
    13681 aagaaaagat tactaaatgt actgccccca aaaagttgga cgaataatta ttgaaaggat
    13741 ttagttctgt attgcacagg gctaagtcct tttagctttg ctttaatgc
//
LOCUS       DARYXW010000053        13560 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.053, whole genome shotgun sequence.
ACCESSION   DARYXW010000053 DARYXW010000000
VERSION     DARYXW010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13560)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13560)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13560
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.053"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(81..1361)
                     /locus_tag="TV191_001286"
     CDS             complement(81..1361)
                     /locus_tag="TV191_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEL1507795.1"
                     /translation="MKIDKRHLLNYSILLPYLILSVIGLIMVYSTTSVSLIQAQANPF
                     RSVANQGLFWVVSLVAITFIYKLKLNFLTNTKVLTIVMLLEILLLIAARFFTTAINGA
                     HGWIVLGPLRFQPAEYLKIIMVWYLALTFSKMQEKIHQYDYQALTRRKWWPTEWGDLR
                     DWRVYSLIMIVLVAAQPDLGNASIIVLTAIIMFLVSGIGYRWFSAILVLITGLSTAFL
                     GMIAVIGVEKVAKIPVFGYVAKRFSAFFNPFRDLTDSGHQLANSYYAMSNGGWFGRGL
                     GNSIEKRGYLPEAQTDFVFSVVIEELGLIGAGLILALVFFLILRIMNVGIKAKNPFNA
                     MMALGVGGMMLMQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVGVGFVLNIDAN
                     EKKEDILKEAELSYRKSVREENSNSKIININQFQ"
     gene            complement(1569..4352)
                     /gene="ppc"
                     /locus_tag="TV191_001287"
     CDS             complement(1569..4352)
                     /gene="ppc"
                     /locus_tag="TV191_001287"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015055932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEL1507796.1"
                     /translation="MSVKKLESYNNQEIIAEEVAILKEILESITRRMIGDEAFARIEE
                     IIDLSEKQDYVLLEQLIAKISNKDMEFISRYFSILPLLINISEDVDLAYEINRQNNTN
                     QDYLGKLALTIASAAEKENAKELLERVTVVPVLTAHPTQVQRKTVLELTNSIHNLLRR
                     YRDVKAGVMNQNKWYSELYRYIDILMQTDIIREKKLKVKNEITNVMQYYNSSLIQAIT
                     ALTSKYKTLAKDKGILLDNPKPINMGMWIGGDRDGNPFVTAETLRLSATVQSEVILRF
                     YIDKLSALYQTFSLSSALTKTSPEVERLASLSSDQSIYRENEPYRRAFHYIQARLTQT
                     LQELIGQPASDQLASRMPATVGSLQSGVTRIVTNSSDQQAPAYKTAAAFKADLVMIEQ
                     SLIAAGDSSLVEGDLQEVLQAVDIFGFFLASIDLRQDSSVQEACVAELLKNAGIVENY
                     SALSEEQKCEVLLKELTEDPRTLSSAAVEKSELLEKELAIYTAARELKDKLGEEVIKQ
                     HIISHTESVSDMFELAIMLKEVGLVDQRQARVQIVPLFETIEDLDNARAIMTQYLSYD
                     IVKSWIATNAGYQEIMLGYSDSNKDGGYLASGWTLYKAQNELTKIGEDNGISITFFHG
                     RGGTVGRGGGPSYEAITSQPFGSIKDRIRLTEQGEIIENKYGNQDVAYYNLEMLISAS
                     INRMVTRMLTNPDEIDGFRKIMDEIVEDSNRIYRELVFDNPHFYDYFFEASPIKEVSS
                     LNIGSRPAARKTITDISGLRAIPWVFSWSQNRIMLPGWYAVGSAFKRFIDKEEGNLAK
                     LQHMYDKWPFFHSLLSNVDMVLSKSNMNIAFQYAQLAESKEVCEVFHTILDEWQLTKN
                     VILAIAQHDELLEETPSLKQSLDFRLPYFNVLNYIQIELIKRLRHEQLDEDYEKLIHT
                     TINGIATGLRNSG"
     gene            4550..6349
                     /gene="pepF"
                     /locus_tag="TV191_001288"
     CDS             4550..6349
                     /gene="pepF"
                     /locus_tag="TV191_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEL1507797.1"
                     /translation="MELKKRSEFPENELWDLTALYKDREDFLLAIEKALQDVGLFQRN
                     YEGKLTTAQDFTQALMEIEQIYIQMSHISTYAFMPQTTDFSDEAFAQIAQAGDDFMTK
                     ASVALSFFDTALANADLAVLDELEKNPYFSATIRMAKIQKEHLLSPDVEKALTNLREV
                     INAPYDIYTKMRAGDFEMEDFEVDGKVYKNSFVSYENFYQNHENAAIRDKAFRSFSNG
                     LRKHQNAAAAAYLAKVKSEKLLADMKGYASVFDYLLAEQEVDRSMFDRQIDLIMTEFG
                     PVAQKFLKHVARVNGLDKMTFADWKLDIDNALNPEVSIDGAYDLVMASLAPLGPAYTK
                     EVERYQTERWVDFAANANKDSGGYAADPYKVHPYVLMSWTGRMSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNTHMSTYYVEAPSTFNELMLSDYLEAQFDTPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGGTFGAEQLNAMMKDVLTEFWGDAVEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLNLKNNPNGANEWLDFLKSGGSRTPLETALLIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYTEEIGHD"
     gene            6342..6845
                     /locus_tag="TV191_001289"
     CDS             6342..6845
                     /locus_tag="TV191_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEL1507798.1"
                     /translation="MTSIYDFSVKRQDGTDCSLEQYQGKVLLVVNTATKCGLTPQYQA
                     LQELYDTYREQGFEILDFPCNQFLHQAPGDATEINAFCSLTYQTTFPRFAKIKVNGKE
                     TEPLFTWLKEQKSGPLGKCIEWNFAKFLIDQKGQVVERYASKTDPKMIEKALQQLLSQ
                     EPIDQSD"
     gene            7344..8537
                     /locus_tag="TV191_001290"
     CDS             7344..8537
                     /locus_tag="TV191_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1507799.1"
                     /translation="MRFQGLTSNFYNLIFSRSSRNIADSFYMIALSVGLLKVYNINAG
                     ELSFLTLVGLLPNMLSFAYGSLIHNLKNDKKWLIVFQMIQLIVIISIIICLSYQLPVV
                     VMYVLNLAFNLVTTVLNTIQMKIVPRTLDDDSDLIEKSVDIQYATSNVLDIVSNFVGS
                     VLLGFVSYLVLLQLSLPFFIGAIAFIFRIQLSPSKLSTTTNDEIEKPASVTESLRAFR
                     ESTFTSFIILVEAFLSGGTDLLLALLPLYLLSEGISIEYIGLVLAAHRAADLLGALVA
                     PRIKVSPRSFFFIDYILSGSSFLLCFMIPYPMVKLLLFFITFTIIGISGNVFEKMIYS
                     EYNHNKLALIYTTNATLYAVFGVLFLLIPFVYSNIRVIGIVINSLTIMIGFGLLIVHL
                     QQERK"
     gene            complement(8736..9200)
                     /locus_tag="TV191_001291"
     CDS             complement(8736..9200)
                     /locus_tag="TV191_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507800.1"
                     /translation="MLRLAFSGFLIGQPVMALLLIYLLYVNVAEAILAMTGYVLLLAC
                     FFGFGPWLFWQMACYSMVLVLWGYFLNPLSDRLSQHRLINQALMAGVCTFCYHILLDS
                     CFAYLYSISWWSYIWAGMLFTVTNALATMGYFLVVLLLLKRLSGKKDPKLSA"
     gene            9468..10316
                     /locus_tag="TV191_001292"
     CDS             9468..10316
                     /locus_tag="TV191_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEL1507801.1"
                     /translation="MRRRIKPIVVVVFFTLIATLLIIGKAHSDNLKSKELKLAKASIP
                     TNTSTSNKSTTSTSETTEFLLNPIIDVSGWQLPSDIDYDLLASNISAAIVRVYGGSQI
                     TAHNNAAFTTGIDKSFKKHITEFQKRHIPVAVYSYALGRSAKEMRAEARTFYKNASPF
                     NPTYYWIDVEEATMTDMNKGVKAFREELKRLGAENVGLYIGTYFMAEQDISTEGFDAI
                     WIPTYGGDSGYYEAAPDTSLDYDLHQYTSQGYLNGFNNPLDLNQIAVTKDTKKTFEKL
                     FGKVKP"
     regulatory      10725..10821
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            10868..11431
                     /gene="thiT"
                     /locus_tag="TV191_001293"
     CDS             10868..11431
                     /gene="thiT"
                     /locus_tag="TV191_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HEL1507802.1"
                     /translation="MSNKTTVTVLIEAAIFAALAMALSFIPDFAGWFSPSYGAIPLVL
                     FSLRRGLRYGLLTGLIWGLLHFILAKIYYLSLSQVIIEYILAFTSMGLAGLFSKPLTN
                     SLGTNKRSFSLLIASAAAFLAIGVRYIWHFIAGVIFWGSYAPKGTSAIWYSFTVNGTA
                     GLLTFIVTLIALLIILPTQPQFFKPSK"
     gene            11592..12071
                     /locus_tag="TV191_001294"
     CDS             11592..12071
                     /locus_tag="TV191_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEL1507803.1"
                     /translation="MAKKVKVKKTLVEQILDKAGIPYQALRINALQGDFPDTINPSDI
                     YKTLALTGDKTGPLIGIIPLTEHLSEKKLAGLSGNKKVSMIPQKELQKITGYVHGANN
                     PVGIRQRHNYPIYIDQSALAKQEIIVSAGELGRSIQINSQALADFVGASFADIKENK"
     gene            12068..12433
                     /locus_tag="TV191_001295"
     CDS             12068..12433
                     /locus_tag="TV191_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HEL1507804.1"
                     /translation="MRLIGNMIWFIFSGFWAWISWSIVGLILCLTIIGIPFGIQCFKI
                     GALGLFPFGKAIEIGQGAGSLLLNIIWIVCCGWSLAIMHLTSALLLCLTIVGIPFARQ
                     SLKLAKISLFPFGAIIYDI"
     gene            12452..13096
                     /locus_tag="TV191_001296"
     CDS             12452..13096
                     /locus_tag="TV191_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEL1507805.1"
                     /translation="MKLYFVRHGKTLWNLEGRFQGANGDSPLLESSKDDLRQLARELW
                     DISFDAIYSSDLKRAVDTARIIVDEANCKTDISYTKQLREWNLGTLEGTKIATVSAIY
                     PSQMSAFYHNLAKFKPSQFKAESLYESTQRLYQLIKSLEDKAYQQVLMVGHGAHLTAS
                     IRALLGFEPGMLRAQGGLDNASLTVIETLDFKHFHCLRWNDTSFLQKKTTRLTP"
BASE COUNT         4068 a         2976 c         2621 g         3895 t
ORIGIN      
        1 caactttttg ggggcagtac acctggtcct ctctaaatgt ttgttataag ccacccgcta
       61 cagttgacaa ggagcttttt ttactgaaat tgattaatat taataatctt actattacta
      121 ttttcttccc ggacagactt ccggtaagat agctctgctt cttttaaaat atcctctttc
      181 ttctcattgg catcaatatt gaggacaaag ccaaccccta cagacaagac cagcaggctg
      241 tttcctccct gtgataagaa tggaaaggta acccctgttg aaggaatgag gccagaaatg
      301 ccaccaatgt taacaaatac ctgcatcagc atcatgccac caacaccaag agccatcatg
      361 gcgttaaagg gatttttggc cttaatcccg acattcatga ttctcaaaat aagaaagaaa
      421 acaagcgcaa ggatcaatcc tgccccaatc agccctaact cctcaatcac gacagaaaag
      481 acaaaatctg tctgtgcctc tgggagatag ccccgctttt caatcgaatt tccaagccct
      541 ctgccaaacc agccaccatt gctcatggcg taataagaat tagccagctg atgtcccgaa
      601 tctgtcaaat cacgaaaagg attgaaaaaa gcactaaagc gcttggcaac gtaaccaaaa
      661 actggaatct tagccacctt ttcaacacca atgacagcaa tcattcccaa aaaagcagtt
      721 gacaaaccag taattagcac taaaatggca gaaaaccaac ggtagcctat accactgacc
      781 aaaaacatga taatagctgt caacacgata atagaggcat tgcccaaatc aggctgcgca
      841 gcaaccagca caatcataat caaggaataa acacgccaat cacgcaggtc accccactct
      901 gttggccacc atttgcgacg cgtcaaggcc tgataatcat actgatgaat cttttcctgc
      961 atctttgaaa aggtgagtgc cagataccaa accatgatga tcttcagata ctctgctggc
     1021 tgaaacctca gaggcccaag gacaatccag ccatgcgcgc cattaatcgc tgtcgtaaaa
     1081 aagcgagcag caatcaacag cagtatttca agcagcataa caattgttaa aaccttggta
     1141 ttggtcaaaa aatttagctt tagcttgtaa ataaaggtaa tagcaactaa gctgacaacc
     1201 caaaagagcc cttgattggc aactgaccga aatggattgg cctgagcctg aatcaagcta
     1261 acactggttg tggaataaac catgatcagc ccaatcacag ataaaatcag ataaggtagt
     1321 aatatggagt aatttagcaa atgcctttta tcaattttca tcatttcccc tataatcttg
     1381 agataatcat tagcattata tcatctttca ttggtaaaac aaaggaaaaa tacattgcaa
     1441 gcacctagcc aagcatggct ctagacaaag cttgctgtat ccttggaatc gctcaatcta
     1501 aaaaacacag acaagccatt ataacctagt agcctgtctg tgtgagctgc tgattgatct
     1561 tcaacggctt agccggaatt acgaagtcct gtagcaatac cattaatagt tgtgtggatc
     1621 agcttttcat agtcctcatc tagctgctca tgacgaagac gcttaatcag ctcaatctga
     1681 atgtagttta acacattaaa atatgggagg cggaaatcca agctttgctt caaggacggg
     1741 gtttcctcaa gaagctcatc atgctgtgcg atagcaagaa taacgttctt agtcagctgc
     1801 cactcatcaa gaatggtatg aaagacctca cagacctcct tgctttctgc taactgcgca
     1861 tattgaaagg caatgttcat gtttgatttt gataatacca tatcaacatt agacagcaag
     1921 gaatgaaaga acggccattt gtcatacata tgctgtaatt tggctaaatt tccctcttct
     1981 ttatcaataa aacgcttaaa ggcagagcct actgcatacc agcctggaag catgatccgg
     2041 ttttgtgacc aagaaaatac ccaaggaatg gcacgcaggc ctgagatatc tgtaatggtt
     2101 ttacgagcag cagggcgaga accaatattt aagcttgata cctccttgat cggactggct
     2161 tcaaagaaat aatcatagaa atgcggattg tcaaaaacca gctctcgata aatgcgatta
     2221 ctgtcttcaa caatttcatc catgattttc ctaaagccat caatctcatc aggatttgtc
     2281 agcatacgag tcaccatgcg attgatagaa gcagaaatca gcatttccaa attgtagtaa
     2341 gccacatctt gattgccata tttattttca ataatctcac cctgttccgt caagcggatt
     2401 cggtctttaa tagagccaaa tggctgtgag gtgatcgcct cataggatgg accgccacca
     2461 cgtccaacag tcccaccacg tccatgaaag aaggtgatgc tgataccatt gtcctcccca
     2521 attttggtca gctcattttg cgccttgtaa agtgtccagc cagacgctaa atagccaccg
     2581 tctttgttgc tatctgaata cccaagcata atctcttgat agccagcatt tgtagcaatc
     2641 caagacttga caatatcata gctaaggtat tgtgtcatga tcgctctagc attatccaaa
     2701 tcctcaatcg tttcaaataa aggcacaatc tgcacacgcg cctgacgctg gtcaacgaga
     2761 ccaacctcct ttagcatgat agccagctca aacatatcag aaacactctc tgtatgtgaa
     2821 atgatgtgct gcttaatcac ctcttcacca agcttatcct tgagctcacg tgccgctgta
     2881 tagatagcaa gctccttttc taacagctct gacttttcaa cagctgccga tgagagggtg
     2941 cgagggtctt ctgtcagctc ctttaagagg acctcacatt tttgctcctc tgacaaagca
     3001 ctgtaattct caacaatacc agcatttttc aaaagctcag caacacaggc ctcctgcaca
     3061 ctagaatcct gccgcagatc aatactggct aaaaagaaac caaaaatatc aaccgcttgt
     3121 aggacctctt gcaaatcccc ctcaaccaag gaggaatccc cagctgcaat gagagattgc
     3181 tcaatcatga ccagatcagc cttaaaagct gctgctgtct tataggctgg tgcttgctgg
     3241 tcactgctat tggtcacaat tcttgtaacg cccgactgaa gcgagcctac cgtagcaggc
     3301 attctagatg ctagctggtc tgaggccggc tgaccaatta gctcctgcaa ggtttgggtt
     3361 agacgagcct gaatatagtg aaaagctctg cggtagggct cattctcacg ataaatggac
     3421 tgatcactag atagactggc cagacgctcc acctcaggac tggtctttgt caaggctgac
     3481 gacagcgaaa aggtttgata aagagctgac aatttgtcaa tgtaaaagcg caggataacc
     3541 tcactttgga ctgttgcaga cagcctcagt gtctctgctg tgacaaaagg attgccatct
     3601 cggtcccctc cgatccacat gcccatgtta atcggctttg gattgtccag caagatcccc
     3661 ttgtccttgg ccagcgtctt atacttgctt gtcagcgctg tgatcgcctg tatcagagag
     3721 ctattgtaat actgcatgac attggtaatc tcatttttga ccttgagctt tttctcacga
     3781 atgatatccg tctgcatgag aatatcaatg taacggtaca gctcactata ccatttgttt
     3841 tgattcatga cacccgcctt gacatcacga tagcgacgaa gaaggttatg aatgctattg
     3901 gtcaactcta gaactgtctt tcgctgaacc tgtgttgggt gagctgtcaa gactggaacc
     3961 accgtcaccc tttccaacag ttccttggca ttttcctttt cagcagcaga agcaatggtc
     4021 agagcaagct ttcccagata gtcttgattt gtattgtttt gacgattgat ttcataagcc
     4081 aaatcaacgt cctctgaaat attaatcaac agcggaagaa tcgaaaaata tcgtgaaata
     4141 aattccatat ctttattgct aatcttagcg atcaattgct ctagaagcac ataatcctgt
     4201 ttttcagata ggtctataat ttcctcaatc cttgcaaagg cctcatcacc aatcatgcga
     4261 cgcgtaatgc tctcaagtat ttcctttagg atagcaacct cttcagcaat aatctcctga
     4321 ttattatagc tctctaattt tttgactgac aaatgacgga cttcccttct tatgctagtt
     4381 ttcctcctat cataccactt tttgctaaaa atgtaagcct attggctagg aatgtttgtt
     4441 ttccttgaca tataagattc attggtacaa aaatgtttgt aaagctttta caggctatcg
     4501 cttctaattt ttgttatact ataggtaatt actcatgaag gagaacatta tggaattaaa
     4561 aaaacgttca gaattccctg aaaatgagct ttgggaccta actgccctct acaaagacag
     4621 ggaagatttt ctattggcca ttgaaaaagc cttacaagat gtcggcctat tccaacgcaa
     4681 ttacgaaggc aaattaacaa ctgctcagga ttttacacag gccttgatgg agattgagca
     4741 gatttatatt caaatgagtc atattagcac ctatgccttt atgccacaga ccactgattt
     4801 ttcagatgaa gcatttgctc aaattgccca ggctggtgat gattttatga ccaaggctag
     4861 cgtagccctc agcttctttg atacagccct agctaatgca gaccttgctg ttcttgatga
     4921 attggaaaaa aatccctatt tcagcgcaac tatccgcatg gcgaaaatcc aaaaagagca
     4981 tttgctaagc cctgatgttg aaaaggcact gaccaatcta cgagaagtga tcaacgctcc
     5041 ttacgacatt tacaccaaaa tgcgggctgg agattttgag atggaggatt ttgaagttga
     5101 tggtaaagtc tacaaaaata gctttgtttc ctatgaaaac ttttatcaaa accatgaaaa
     5161 tgctgccatt cgtgacaagg cctttcgttc cttctcaaac ggactgcgta agcaccaaaa
     5221 tgcagcagcc gcagcctatc ttgctaaggt caaatcagaa aagctcttag ctgatatgaa
     5281 gggctatgcg tctgtttttg attacctgct ggctgagcag gaggtggacc gcagcatgtt
     5341 tgaccgtcaa atcgacctca tcatgaccga atttggtcca gttgctcaaa aattcttaaa
     5401 gcatgtggca agggtaaatg gcttagacaa gatgactttt gcagactgga agctagatat
     5461 tgataacgcc ctcaatccag aggtctctat tgatggagct tatgacttgg tgatggcatc
     5521 attagcacca cttggtccag cctatacgaa agaagttgaa cgctaccaaa cagagcgctg
     5581 ggtggacttt gctgcaaatg ccaataagga ttctggtggc tacgctgctg acccttacaa
     5641 ggttcaccct tatgtgctga tgagctggac aggccgtatg tctgacgttt acacgctgat
     5701 ccatgagatt ggccattctg gtcagtttat cttctctgac aatcaccaaa gctacttcaa
     5761 cacacacatg tcaacctatt acgttgaagc accttcaacc ttcaatgagc tgatgctaag
     5821 tgattatttg gaggcacaat ttgacacgcc tcgtcaaaaa cgctttgcac tggcgcaccg
     5881 cttgacagat acttatttcc acaacttcat cacgcatttg ttagaggctg cctttcagcg
     5941 taaggtttat accctcatcg aagagggggg cacctttggt gcagagcagc ttaatgccat
     6001 gatgaaggac gttttaacag agttctgggg cgatgctgtt gagattgatg atgacgctgc
     6061 ccttacctgg atgaggcagg ctcattatta catggggctt tatagctata cctattctgc
     6121 agggcttgtg atttcgactg ccggctacct caatctaaag aataacccaa atggtgccaa
     6181 cgaatggctt gatttcttaa agtctggtgg cagtcgtacc ccgcttgaga cagccctact
     6241 catcggagct gacatctcaa cagacaagcc gcttcgcgat accattcaat tcttgagcga
     6301 tacggttgat cagatcattg cctatacaga ggaaattggt catgactagc atttatgact
     6361 ttagcgttaa aagacaagat ggcactgatt gttcactgga gcaataccaa ggaaaggtcc
     6421 tattagtggt caacaccgcc actaaatgcg gattaactcc tcaatatcaa gcattacaag
     6481 agctttatga cacctacagg gaacaaggct ttgaaatcct tgatttcccc tgcaatcaat
     6541 ttttacatca ggcaccgggt gatgctacag aaatcaatgc cttttgcagc ttaacttacc
     6601 agaccacctt cccacgcttt gccaaaatca aggtcaacgg caaggagaca gagccattat
     6661 tcacttggct caaagaacaa aaaagtggcc cactcggcaa gtgcatcgaa tggaacttcg
     6721 caaaattttt aattgatcaa aaggggcagg ttgttgagcg ctatgcctca aaaacagacc
     6781 ccaaaatgat tgaaaaagcc ctacagcaat tgctttccca agagccaatt gaccaatcag
     6841 actaacgaag tcctatcaaa aaacaagcca agatccttat ttcttggctt gtttttatat
     6901 ctaaagcttc ttgctttgcc gaggagccgc taaaggtcgg ctatttgctt gtctattctt
     6961 caaagaactt ttttgaaggg gaccttgtcc tcacacctaa gcttactttt ttcaatcaaa
     7021 tcattcaagc tgcttcctgt aaggactggt gcacttgagc aatgataact tatgctagcc
     7081 tttttatgtt tatcaaaaag tacctgttca catgatttaa ggacatttac ttcagtcatc
     7141 aacagtaaaa agcattgacg catgtgatta ggattgttaa aatcatctta taaaattaag
     7201 aaaaacacat gactattgaa tgatctaagc tgtgctgcca aaagccctta cccttaatcc
     7261 tatcacagtg gacagcatgc aaatgacctc aggagtttca aatgacattc aaatagattg
     7321 tactgattgg agagtttatc agcatgagat ttcaagggtt aacaagtaac ttttataacc
     7381 tcatttttag taggtcaagt cgcaatatcg cagacagttt ttacatgatt gctttgtctg
     7441 ttggtttact taaggtttac aacattaacg cgggagaact ttcttttttg acattggttg
     7501 gtttattgcc aaatatgctg tcttttgctt atggttcttt aatccataac ttaaaaaatg
     7561 ataaaaaatg gttaattgtc tttcagatga tacagctcat tgtcatcatc agtattatca
     7621 tctgcttaag ctatcagcta ccggttgttg tcatgtatgt gctcaacctt gcctttaact
     7681 tggtcacaac cgtattaaat accattcaaa tgaaaatcgt tcccagaaca ctagacgatg
     7741 attcagacct cattgaaaaa tcagtagata ttcaatatgc tacatcaaac gttctagata
     7801 ttgttagcaa ttttgtgggc tctgttcttc ttggctttgt ttcctatctc gttttactgc
     7861 aattgagcct gcctttcttt ataggagcca tagcttttat ttttaggatt cagcttagcc
     7921 cgtctaagct tagcaccacg actaatgacg agattgaaaa acctgcttct gtaacagaat
     7981 cactacgtgc atttagagag tcgaccttta cttcctttat catcttggta gaagcctttc
     8041 tcagtggagg aaccgattta ttactagcac tccttccatt gtatctactg tctgagggca
     8101 tttcaatcga atacattggc cttgttttag cagctcacag agcagcagat ttattagggg
     8161 ctctggttgc acctcgcatt aaggtatctc cacgaagctt ctttttcatt gattatatcc
     8221 tgtctggaag cagcttcttg ctttgcttta tgattcccta tccgatggta aaattacttt
     8281 tgtttttcat taccttcacg attattggca tatcgggcaa tgtatttgaa aaaatgattt
     8341 atagtgagta taaccacaac aagctcgcct tgatctacac gaccaatgca accttatacg
     8401 ctgtctttgg tgtcctattt ttactgattc cctttgttta tagcaacata agggttatag
     8461 gaatcgtgat caacagcctg acaataatga taggatttgg attactcatc gtccatttac
     8521 agcaagaaag aaaatagctt agttctaaaa ccagcaaaat ggataaagcc cttcaacaaa
     8581 ataagcttcc ttacaaaaag gaatcagaag tcactattaa ataatcaaaa actatcaatc
     8641 gatataagaa gatttaagga gcaaaaaaaa gaaattactg atcggcaaca actgcactac
     8701 taccgggttg ctgcgtcaaa gccagcatta agaccctaag ctgacagctt agggtctttt
     8761 ttgccagata gccttttaag caataaaagc actaccagga aataacccat agtggctaag
     8821 gcattagtca ctgtaaaaag cattcctgcc catatatagc tccaccaaga gatactatag
     8881 aggtaagcaa aacaactatc tagcagtata tgatagcaaa aggtacagac tcctgccatt
     8941 aaggcttgat tgatcaaccg gtgctgcgat agcctgtctg ataagggatt caagaaatac
     9001 ccccacaaaa ccaataccat tgaataacaa gccatttgcc aaaagagcca aggaccaaag
     9061 ccaaaaaagc aggctaataa gagcacatag cccgtcatcg ctaaaatagc ctctgctaca
     9121 ttaacataga gtaggtaaat caacaaaaga gccatgactg gctggccaat gagaaagccg
     9181 ctaaaggcta ggcgcagcaa gaagcaacat acagaaacga tagctagtcg actaataact
     9241 ttggtagaca taatccctct ttgagtgttt tttatctatt atgacagatt ttgcatctct
     9301 tgaccagcat caacagcttt ttgatagatg attacaagac aggtagacta aaatcaaacg
     9361 aaaatagata ggacctgatc tgccaaagct gtcctaagga gctaaaaacc taagaaaatc
     9421 gtaagaccac tttgattttt tgaagcattt aaggtacaat aagactgatg agaagaagaa
     9481 taaaacctat tgttgttgtg gtcttcttta cgctgattgc tactttgtta atcattggaa
     9541 aggctcattc tgataatctc aaaagtaaag agctaaagct tgctaaagca agcattccca
     9601 ctaacactag cacgtccaat aagtcgacta caagcacatc tgaaactact gaatttctac
     9661 taaaccccat tattgatgtt tctggctggc agctgccaag tgacattgat tatgaccttt
     9721 tagcatctaa tatttctgca gcaattgttc gtgtttatgg cggatcacaa attactgccc
     9781 ataataacgc tgcctttact accgggattg ataaatcatt caaaaagcat attactgaat
     9841 ttcaaaaacg acatatccca gttgctgtct atagctatgc tctaggtcgt agtgccaagg
     9901 aaatgcgagc tgaagcaaga accttttaca aaaacgcttc tccttttaac ccaacctatt
     9961 attggattga tgttgaagaa gctaccatga cagacatgaa taaaggggtc aaggcgttta
    10021 gagaggagct aaaacggtta ggtgcagaaa atgttggcct gtatatcggt acttatttta
    10081 tggccgagca ggacatttca acagaaggct ttgacgccat ctggattcct acctacggtg
    10141 gtgattctgg ctattatgag gcagcgccag ataccagcct agattacgac ctgcatcaat
    10201 atacctcaca aggctacctc aatggcttta acaatccatt agatttaaat caaatcgctg
    10261 tcacaaaaga cactaaaaaa acctttgaaa agctttttgg gaaagtaaag ccttaaaggc
    10321 atcgaagcaa gtcgtcaaaa cctttgaatg tcagtcattc cgaatgcctt aaaccctaag
    10381 ctcaaagccc aggtaagcca atcctaaaga aggttgctcc tattcttatt tctttaagaa
    10441 taaagaccct ttcatcaatc taagaaggct aaagattgct ggctgttaaa aaatgctata
    10501 ttgattcctt ctgacgtcaa tttgagcatt aaggacaact gtatttagaa gctgatattg
    10561 ataacaccaa tcactgcttg tttttggttt aaaggctggc tgttagctca gccttttttg
    10621 gtgtgatcag tttttgacta taccgctatg ccaactttgt ctcatgattt caaggccaaa
    10681 ttcttgacat tgctgccatc tcattttata atatagaaaa tataattatc acaaaggagt
    10741 gctttggctg agatcgcgta tgcgaaatcc taaggacctg atcttgttaa tacaagcgta
    10801 gggattgtga ccaatatcat tagcattgga aaacgattct ctttttgtgt gcaaaaggag
    10861 tttttttatg tcaaacaaga caactgttac tgttctgatt gaggctgcta tttttgctgc
    10921 tcttgctatg gctttatcat ttataccaga ttttgccggc tggtttagcc cctcttatgg
    10981 tgctattcct ctcgtcttat tttcgcttag gcgtggcctc aggtatggcc tgctaactgg
    11041 cttgatttgg gggctgctcc attttatttt agcaaagatt tactacctca gtctatctca
    11101 ggttattatt gaatatatcc ttgcctttac ctcaatgggc ttagctggcc tgttttctaa
    11161 gcccttgact aatagtctag gtaccaataa aagatccttc agccttctaa ttgctagcgc
    11221 agctgccttt ttagcgattg gggttcgtta tatctggcat tttatcgctg gtgttatttt
    11281 ctgggggagc tatgctccta agggcacctc tgctatttgg tattccttta ctgtcaatgg
    11341 cacagcaggt cttctaacct ttatcgtgac acttattgcc ctgctcatta tcctaccgac
    11401 acaaccacaa ttttttaagc ctagtaaata agacaagagt tcgaatcgga aaatcataaa
    11461 gctgaggcag gtctgtaaag gcctgctctt tctaagccta gaaaaaggat caaaaaagac
    11521 tttttttcag tctaatggta tactactact gttagactgt ttttgatatt gacacataag
    11581 gaagttaaca aatggctaaa aaggtaaaag taaagaaaac gctggtggag caaatcctag
    11641 acaaggcagg tatcccctat caagcgctta ggatcaatgc cttacaaggt gatttcccag
    11701 acacaatcaa cccatcagat atttataaaa ccctagcact gactggcgat aagacaggcc
    11761 ccttgattgg gattattcct ttgacagagc atttatctga aaagaagcta gcaggccttt
    11821 ctggaaacaa aaaggtctcc atgattcctc aaaaggagct gcaaaaaata accggctatg
    11881 ttcatggtgc aaacaatcca gttggtattc gacaaaggca caattaccct atttacatcg
    11941 accagtctgc actagccaag caagaaatta tcgtatcagc tggtgagctt ggtcgatcca
    12001 tacagatcaa tagtcaagcc ctagcagatt ttgttggggc tagctttgct gacataaagg
    12061 agaacaaatg agacttattg gaaatatgat ttggtttatt ttttcaggct tttgggcctg
    12121 gatttcttgg tctattgttg ggcttatcct atgcttaaca attatcggga ttccttttgg
    12181 gatacaatgc ttcaagatag gcgctttggg tctttttcct tttggaaaag ccatcgaaat
    12241 tggccaagga gcaggcagcc tgctgctcaa tatcatctgg attgtctgct gtggctggag
    12301 cttagcgatc atgcatttga cttctgccct tctcttgtgc ctcacgattg ttggcattcc
    12361 atttgcccgg caatctctaa aattggccaa gattagcctc tttccttttg gagccatcat
    12421 ttatgacatt taattaggaa gcaaaagact tatgaaattg tattttgtca gacatggtaa
    12481 aaccttgtgg aacctagagg gccgttttca gggagctaac ggagattcgc ccttgcttga
    12541 aagctctaag gacgatttgc gccagctagc aagagagctg tgggacattt cttttgatgc
    12601 gatctactcc agcgacctaa aaagagctgt tgatactgct cgcattattg tggacgaagc
    12661 taactgcaag actgatatta gttataccaa gcagctgaga gaatggaacc taggcaccct
    12721 ggaaggaacc aaaatagcaa ctgtatccgc catctacccc agtcagatgt cagcctttta
    12781 tcacaattta gccaaattca agcccagtca atttaaggct gaatcccttt atgaaagcac
    12841 acaaaggctt tatcagctca ttaaaagttt ggaagataag gcctatcagc aggttttaat
    12901 ggtaggacat ggcgcccatt tgacagcttc tattcgtgct cttttaggct ttgagccagg
    12961 tatgcttcgg gcacagggag gactggataa tgccagccta accgttatag aaaccttgga
    13021 tttcaaacac tttcattgtc taaggtggaa tgatacatca tttttacaaa aaaagactac
    13081 tagattaaca ccctagtagc tcttaagcac aaagctccaa gacagctaaa ctgtactcca
    13141 ttggttagag aacacatctc attttttgag ggacgcttta ttagctgtag gaagttatga
    13201 aaagctaaat acacgagagg actaaattgg acaagctcaa aagtttgaca atgtatttca
    13261 aaaaaggatt gaattctgta tcgaacagga ctcagtcctt tttatcattt atcaagccga
    13321 ccaaggcttt caaccacgac aaacgcgcaa aacagttatt tcctgatgat agtagagact
    13381 acagcagata ttttcaatga ttttcttgta gtaacatcta tacaaaacaa tacagctcat
    13441 tgaaatatag gaacattaaa attcagaaag atttcttttc ttgctaaaaa tctttcatcc
    13501 atttcaaact ggttttcatt tgtcctctcc tttttcagtt ctgctttttc tccataagct
//
LOCUS       DARYXW010000054        13553 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.054, whole genome shotgun sequence.
ACCESSION   DARYXW010000054 DARYXW010000000
VERSION     DARYXW010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13553)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13553)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13553
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.054"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            120..476
                     /locus_tag="TV191_001297"
                     /pseudo
     CDS             120..476
                     /locus_tag="TV191_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677601.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(639..1232)
                     /locus_tag="TV191_001298"
     CDS             complement(639..1232)
                     /locus_tag="TV191_001298"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEL1507806.1"
                     /translation="MTKVIGITGGIASGKSTAVALIRQAGYQVIDADQVVHELQKKGG
                     KLYQVLLETFGQDILLPSGQLDRPKLAELLFAHSENMAKSSQQQNAIIREALAKQKEE
                     LSQTEAIFFMDLPLLVELGYQDWFDAIWLLYVDEETQLKRLMKRNQLTELAARQRIAS
                     QLPMSQKRAYADLVIDNTGDFQALETQISKALHDLEA"
     gene            complement(1229..2050)
                     /gene="mutM"
                     /locus_tag="TV191_001299"
     CDS             complement(1229..2050)
                     /gene="mutM"
                     /locus_tag="TV191_001299"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEL1507807.1"
                     /translation="MPELPEVETVRRGLERLVVGKQIAAVTVRVPKMVKTDLEHFVMT
                     IPGQQVQGVDRRGKYLLFDFGQLVMISHLRMEGKYLLFPDTVPEHKHFHVFLTMTDGS
                     TLVYQDVRKFGTFDLLPKAELAAFFQKRQLGPEPTKQTFQLKTFEAALLASKKTIKPH
                     LLDQTLVAGLGNIYVDEVLWAARVHPERRSASLKKAEIKRIHDETIRILQLGIEKGGS
                     TVRTYQNTLGMNGSMQHYLMVYGQTGKPCQRCGTSIVKLKVGGRGTHVCPRCQKQ"
     gene            complement(2465..4264)
                     /locus_tag="TV191_001300"
     CDS             complement(2465..4264)
                     /locus_tag="TV191_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEL1507808.1"
                     /translation="MERFQISDQFYLDGRSLQILSGAIHYFRIHPDDWYHSLYNLKAL
                     GFNTVETYVPWNLHEAREESYDFSGQLDVEAFLTLAQQLGLYAIVRPSPYICAEWEFG
                     GLPAWLLTKNCHIRSSDPVYLAYVRRYYEELLPRLARHEWQQGGNILMFQLENEYGSY
                     GEDKAYLTAVKGFMEEHLSAPLFTADGPWRATLRAGSLIEDDVFVTGNFGSRAQENFA
                     DMQAFFSEHGKHWPLMCMEFWDGWFNRWHEPIIKRDPEERADAVMEVLAQGSINLYMF
                     HGGTNFGFMNGCSARKQLDLPQVTSYDYDAILDEAGNPTAKFYAIQKRLTAELSEIEV
                     TPPLIKPLMSLPLIGLKDKVSLFSTLEHISSCQTACYPSNIEALGQSTGYILYRTHLL
                     KDKREDERLRLIDSRDRAQVFLDGQKVATQYQETIGDDIIINQQHALSQVDVLIENMG
                     RVNYGHKLTAPSQSKGLGRGMMADLHFVTNWEMYCLPLDDLSQLCFDGDFYEGQPGFY
                     HYQFECHEPEASYIDMTGFGKGCVFINNHPIGRFWEVGPLLTLYIPKGYFNKGLNDIV
                     IFETEGVYQDSIRLVDRPISIDYPQADDRTDQT"
     gene            complement(4425..9065)
                     /locus_tag="TV191_001301"
     CDS             complement(4425..9065)
                     /locus_tag="TV191_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 16 glycosylhydrolase"
                     /protein_id="HEL1507809.1"
                     /translation="MLFNPIGKEQIRKYAIKKLSVGVASVCVGIGLAAGLPVAVYADD
                     VSEVSLQQPTKAAVTEISHEQEPQATDTDSEALVVSEETTVDEAVVANAVTSNAADQT
                     ADEEKSNAPIELNKVANGGFDNDYVSNKNQWQYREGGHSVLTTENGNSYAEVTSGTLD
                     EHILQKVSTTVGKTYTLEADVKVEADTPHNGLYLTAKESNHNLQGPVIKEVSLTDTDG
                     TWSHIKLSFTATTSETFVGLVKWLEASSPEALAASASIDNVSVVEENDYELIWQDEFS
                     GDRLNQENWGYELGSIRGNEQQHYTDSTENVYLDNGNLVLNVTERYGEDRYANPRGGT
                     SARQVIYDSGSVRTVGKQEFLYGRIEARAKLPKGKGAFPAFWTLGADFTLDGDIASTQ
                     GYGWPSTGELDIMELIGAPNGEHEGELAEGDQSNKTVYGTPHFYYIKGDADKDGSYSP
                     TALGGNLTLSDDFYDDYHIFGINWYPDKIEWYVDGIVYNTMYLTGDDRLEAAAAAFNK
                     PQYLQFNLATGGNWSKNAGYYLASDETAFVIDYVRYYQDAEQKAASEAYYASQPVLKG
                     VKDLTMLEGTSPDLAQAVTTDQEGYVVDFSVENEYLFTNKGGNTNAALQAAGRDDLSA
                     LSELAPGIYNIYYSAVPYNADLGSTVTPTAKIAREVAILTVLPKEGLIGKKGEPLSTV
                     ALPANWQWVTPEEILGSAEHYQIKYTTEGGRAVYTSIEASYISDQPISDQASILVDLG
                     NAILDATAEKAAVTDDEALGKLDDVMNLTQGTVTIRYRLDTADTTVRSSSPLALLSIS
                     NQASANEYASFFIEPKNNKIGLEFKGAEVPIVKVGSGFNLLTNSDWQTISYVFTGSRL
                     KIYLNGDLYGEADFAGFMKQLPWKASADTLTIGGLKRTYDGESVLHWGLKGLVDQVLI
                     DTDVYDLTDIAKAHQPTLRPVTGEKTNVWDKYDEGVFEYRIPSVVKTPSGTLIAAADA
                     RKKHYNDWGDVATVVRISHDDGKTWSNNITVLDMPTQPYFTTQYSLADWNTNMTQSAF
                     SIDSTLLTDASGKLYLLVDVFPESQGAVASKAGSGYELINGQYYLNLYDFDNNKYTVR
                     EGGIVYDQSGHQTDMYVDEGNFETAFSTRGNLYQTEAGEDILLGNIYLRSGRTKQGIT
                     REGSQTAPLFTYMTSFLWLLTSEDEGQTWSTPLDITPQIKEDWMGFLGTGAAAGIEID
                     AVNAEGEQVKRLVFPIYYTNQQNATSASLGRQSSANIFSDDGGQTWQRGESPNDGRIY
                     GHNQQTTSKDFDTSVTELTENQIIQLNNGHLLQFMRNTGKTIVIARSTDYGMTWDDNP
                     TITDLPEPYVNLSAIHMMVDGKEYVVLSNPLGEPSGEQLTIRNQRMKGILRVGEVLED
                     DSIHWVASTIFEPKRFAYSSLVQLDDERVGLLYEYSGQITYSTFNIKQMISDQFREDK
                     AEIEEVTITSAAPKQNGKVSITIQMTFNQPMFILGDRQLAVTVNGVDKLASYVSGDGT
                     DTAIFELSLESMPEGPITVLPQFDHTIVETKYGIRLTDDKAYTVSYPAAVTA"
     gene            complement(9238..10585)
                     /locus_tag="TV191_001302"
                     /pseudo
     CDS             complement(9238..10585)
                     /locus_tag="TV191_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677596.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
     gene            complement(10650..11966)
                     /locus_tag="TV191_001303"
     CDS             complement(10650..11966)
                     /locus_tag="TV191_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL1507810.1"
                     /translation="MTKFEDFIQQKLVPVAGRLGSNRFLIAIRDGITYAMPLILIGSF
                     LMVIASLPIPGWEAWLGEIGVSTYLWKGVDSSFNLIALVAAFGISYSLAKQYKADGIS
                     AGIINISAFLTVTPFTVSFVNESGKALGEVAGIAPSYLSSGGLFVAIVLGLVNGYAYQ
                     WFMKKDIRIKMPEGVPPAVSKSFSAIIPGAVIIVFWLAVYAFLDHFSLPNVHDIVKSV
                     LGVPFGLLGSTLFGNFIVVLLNGFLWFCGVHGGNVLNNPIMKPIWLSNLTENMAAHKA
                     GQELPHVFTSVFMDNFVFIGGAGATIGLVLALAWLARRRKASQQAKVLSPLTLIPGFF
                     NINEPTMFGLPVVLNLLTVIPFVLAPVMNLFVAYFAFASGIVPGTYADPGWTMPPVIS
                     GFLATGSWQASVLQLVLIILDILLYLPFIINVERRWQASEQTKNEG"
     gene            complement(11959..12291)
                     /locus_tag="TV191_001304"
     CDS             complement(11959..12291)
                     /locus_tag="TV191_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEL1507811.1"
                     /translation="MEDKQLETIMGLIMHGGSAKSLAMEAIAFAKKGELNQAQESLKQ
                     ADKALVQAHHAQTDMLTQEARGNATPVSLLLVHGQDHLMTSITFVDLARELVSIYERL
                     TSQGGNND"
     gene            complement(12301..12618)
                     /locus_tag="TV191_001305"
     CDS             complement(12301..12618)
                     /locus_tag="TV191_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1507812.1"
                     /translation="MSKKQIMLACAAGMSTSLLVTKMEKAADNRGLEADIFALPLTEA
                     EDYALSHPVDVVLLGPQVAYQLSAFQESLAEKDIPVAVVPMVDYGMMNGDKVIALAES
                     LMK"
     gene            complement(12642..13541)
                     /locus_tag="TV191_001306"
     CDS             complement(12642..13541)
                     /locus_tag="TV191_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEL1507813.1"
                     /translation="MKTRLLSASSSEMLQLTSLELKQAIKASEGRTIVSENVAPRPSW
                     TGDDLTNAEVAAAFSADLILLNCVDVFDVQISGLPATDQPILELRRLVGRPIGVNLEP
                     IDLDVDMTEKRLELVEGRQATAKTFQEIEALGFDFVCLTGNPGTGVSNNQIERAIQQA
                     KHYFSGLIIAGKMHAAGSNEAVIDLETVRRFIEAGADVILVPAVGTVPGFTEGDLRAI
                     VEEVHAHDALVMSAIGTSQEGSDTTIVRDIAIRNKICGVDIHHIGDAGYSGIAPVENI
                     FALSDAIRGKRHTIVRMSRSIRR"
BASE COUNT         4068 a         3412 c         2516 g         3557 t
ORIGIN      
        1 tcggtgagga agcagctcaa aaacaagaaa aaccagaata tcatttagat atatatataa
       61 ctacagaaaa aaattattaa cataaacctt atcaaaacct gcttggttct actctaattc
      121 ctaaacttga ccctaagcct gaaccagaac cagatcctaa gcctaagcca gatcctgaac
      181 caatgcctaa accagagcct aagcctgaac cagagcctaa acctgaacct aagcctgaac
      241 caatgcctga tccggcacct aaaccagagc ctaagcctga accaatgcct aaaccagagc
      301 ctaagccaga gacaaaacct caaaaaccaa ccaagccgtc aaacgctact agccaatcta
      361 gtggcaaagc actaccaaaa acaaatgaca ctggcagctt gatgactgca cttggtacag
      421 gcttactctc tcttcttgga ctaggcttcc tggcaaaacg caaaagaaag caataagctg
      481 aataagctaa tgcaagacag cactagtata taatgcgtgc atggtccatc taatgcagca
      541 caaaagcctt atcgcaccac gaatgggtac gataaggctt tttgcatacg ctatagaagc
      601 tccaaaacca ctagactagg gcaacagcat ggcaaggctt acgcctctaa atcatgcaga
      661 gccttactaa tctgtgtctc taaagcctga aaatcaccag tattatcaat cactaaatca
      721 gcataagctc ttttctgaga catcggcagc tggctagcaa tccgctgcct agcagctagc
      781 tctgtcaatt gattacgctt catcaggcgc ttgagctgag tctcctcatc aacatagagc
      841 agccaaatag cgtcaaacca atcctgatag cccagctcaa ctaaaagcgg taaatccata
      901 aagaaaatag cctctgtttg agatagctcc tctttttgct tggctaaggc ttccctaatg
      961 atagcattct gctgctggga agatttcgcc atattttccg aatgagcaaa cagcagctcc
     1021 gctagcttag gtctgtctaa ttgccccgat ggcaataaaa tatcctgtcc aaaggtctct
     1081 agtaggacct gataaagctt gccgcccttt ttttgcagct catgcaccac ctgatccgca
     1141 tcaatcacct ggtagcctgc ttgtctgata agtgcgacag ccgttgattt tccggaggca
     1201 atacctcctg taatgccaat tacctttgtc attgcttctg acacctagga cagacatgtg
     1261 tccctcttcc tccaaccttg agctttacaa tggaggtccc gcagcgctga cagggcttgc
     1321 ctgtttggcc atagaccatc aaataatgct gcatactacc attcattcct aaggtattct
     1381 gataggttct aaccgtcgag ccaccctttt caatacctaa ttgtaaaata cgaatcgttt
     1441 catcatgaat ccgtttgatt tctgcctttt tcaggctagc agatcgacgc tcagggtgta
     1501 ctctagctgc ccatagcacc tcgtccacat agatatttcc aagaccagcc actaaagtct
     1561 gatccaaaag atgaggctta atggtctttt tagaggctag cagagcagcc tcaaaggtct
     1621 tcaattgaaa ggtctgcttc gtcggctcag gaccaagctg acgcttctgg aaaaaagcag
     1681 ccagctcagc ctttggtagc aaatcaaagg ttccaaactt tctcacatct tggtaaacca
     1741 gcgtggagcc atcagtcatt gtcaaaaaga catgaaaatg cttatgctca ggtaccgtat
     1801 caggaaacaa gaggtatttc ccctccatac gcaaatgcga gatcataacc agctggccaa
     1861 agtcaaagag caggtacttc ccgcgacgat ctaccccttg cacctgctgc ccagggatcg
     1921 tcatcacaaa atgctcaagg tctgttttga ccatcttggg caccctaact gtcactgctg
     1981 caatctgctt gccaacgact aagcgctcaa gcccgcgtcg cactgtctca acctcaggga
     2041 gttcaggcat aattaaagat accaaacgcg ctaacaaaga aaccacataa ccaaaaccag
     2101 cagaaccagc cagttttagc actctttact cagtctcaat gttacaaaca cgcttccttt
     2161 ctataagcta ctattagaaa gccccaccca aaacctcaat aagcttgagc acaaaggact
     2221 atcctttgat aagaactgtt atcattctta ttttacgcat aatccataaa gaaagcaact
     2281 ctcacgaaca gcctttgcag tcactgccgc tatagcatca gaaaagcaca tctcgcccgc
     2341 caatccagca agcaaagaca aagcccctga gctagcctat tgtttgccag cccaagggca
     2401 cgttgtggcc tttagtgtct gtaaatagaa aaccaagcaa tgctgcaagc ctcaactgac
     2461 aatgctaggt ctgatcagtc ctgtcatcag cttgcggata atctatacta attggcctat
     2521 caacaagacg gatactatcc tggtaaacac cttctgtttc aaaaataaca atgtcattta
     2581 atcccttgtt gaaatagccc tttggaatat aaagggttaa taagggaccc acttcccaaa
     2641 aacgaccaat agggtgattg ttgataaaga cacaaccctt cccaaagcca gtcatatcaa
     2701 tatagcttgc ctcaggctca tgacattcaa attgataatg ataaaagccg ggctgcccct
     2761 cgtaaaaatc gccatcaaaa caaagctgag acaaatcatc aagcggcaga caatacatct
     2821 cccaattggt cacaaagtgc aagtcagcca tcataccacg tcctagaccc ttactttgac
     2881 taggtgctgt cagcttgtgc ccataattga cccggcccat attttcaatt aaaacatcga
     2941 cctgactcaa ggcatgctgc tggttaatga tgatatcatc accaatcgtc tcctgatact
     3001 gtgttgcaac cttttgacca tctaaaaaga cctgtgctct atctctacta tcaatcaagc
     3061 gtaaacgctc gtcctcacgc ttatccttca aaagatgtgt ccgatacagg atatagcccg
     3121 ttgattgccc taaagcctct atgttactag gatagcaagc agtctgacag ctgctgatgt
     3181 gctccagcgt gctaaacaga ctaaccttgt ccttcagacc aatcagaggc agtgacatca
     3241 agggcttaat caagggagga gtaacctcta tctctgaaag ctccgcggtc agacgctttt
     3301 gaatcgcgta aaacttagct gtcggattgc cagcctcatc taggatagcg tcataatcat
     3361 aggaggtcac ctgcggaagg tccaattgct ttctggcaga gcagccattc ataaacccaa
     3421 agtttgttcc cccatgaaac atatacaggt taatactgcc ctgcgccaaa acctccatca
     3481 ctgcgtcagc tcgctcttca gggtcgcgtt tgatgatggg ctcatgccaa cgattgaacc
     3541 agccgtccca aaattccata cacattaaag gccaatgctt gccatgctca gaaaagaagg
     3601 cctgcatgtc agcaaaattc tcctgtgccc ttgagccaaa gttgccagtc acaaagacat
     3661 catcttcaat cagactacca gctctaagag tggctcgcca aggaccatct gctgtaaaca
     3721 agggcgcact gaggtgctcc tccataaagc ccttaacagc tgttaaatag gccttatcct
     3781 ctccatagga gccatattca ttttcaagct gaaacatcaa aatattgccg ccctgctgcc
     3841 attcatgcct tgctagtctc ggcagcagct cctcataata gcgcctcaca taggctaaat
     3901 agacaggatc agacgacctg atatgacaat tctttgtcag cagccaagca ggtaggccac
     3961 caaattccca ttctgcacaa atataaggac taggtctgac aatagcatag agccccaatt
     4021 gctgcgccag cgtcaaaaag gcttccacat ctaattggcc agagaaatca tagctttcct
     4081 ccctagcctc atgtaaattc caagggacat aggtctcaac cgtattaaat cccagtgcct
     4141 ttaaattata aagcgaatga taccaatcat ctgggtgaat tctaaaataa tggatagccc
     4201 ctgacaggat ttgcagcgat ctaccatcta aataaaactg atctgaaatc tgaaaacgtt
     4261 ccaagcttaa ttcctcactt attattgcta ttagcctact aggcctcatt gctgagcggc
     4321 ttggaatggc ccattctagc aacagcgaac aggccattca gcagacaggc taacttatct
     4381 tatggtaaca attgtaaaca ctatctacag tctgactcct catgctatgc tgtcacagca
     4441 gcaggataag agacagtgta tgccttgtca tctgtcaatc taatcccata tttggtttca
     4501 acaatagtat ggtcaaactg cggtaaaaca gttatcggtc cttcaggcat actctccaga
     4561 gacaattcaa atatcgctgt gtctgtgcca tctcctgaaa catagctggc aagcttatct
     4621 acgccattta cagtaactgc taactgacga tcaccaagaa taaacatcgg ttgattaaag
     4681 gtcatctgaa tggttatgct tactttgcca ttttgctttg gagctgctga cgttattgtt
     4741 acttcttcaa tttcagcctt atcctcacga aactggtctg agatcatctg cttgatatta
     4801 aaggttgaat aggtgatctg accactatat tcgtataaca aaccaaccct ctcgtcgtct
     4861 agttgaacca agctagagta agcaaaacgc tttggctcaa aaatggttga agcgacccaa
     4921 tgaatgctat cgtcctctaa gacctcaccg acacgcagaa tccctttcat gcgctgattt
     4981 ctaatcgtca gttgctcacc tgagggctct cctaaaggat tggataaaac aacatattct
     5041 ttgccatcaa ccatcatatg aatagctgac aaattgacat aaggctctgg gaggtctgtg
     5101 attgtaggat tatcgtccca agtcatacca tagtctgtgc ttctggcaat aacgattgtc
     5161 tttccggtat tgcgcataaa ctgtaataag tgaccattgt ttagctgaat gatttgattt
     5221 tctgtcaatt ctgtgactga tgtatcaaaa tccttagagg ttgtttgttg gttatgacca
     5281 taaattctgc catcatttgg tgattcacct cgttgccatg tttgaccgcc atcatcacta
     5341 aaaatattag cactgctttg acgacctaga ctagctgatg tcgcattttg ttgattggta
     5401 tagtaaatcg ggaaaactaa ccgtttcacc tgctcaccct ctgcattgac tgcgtctatt
     5461 tcaatgccag ctgcggcacc cgtacctaaa aatcccatcc agtcttcttt tatttgtggg
     5521 gtaatatcaa gaggtgtgga ccaggtttgc ccttcgtctt cactggttag cagccataaa
     5581 aagctggtca tgtaagtaaa tagaggagct gtttgtgagc cttctctagt gatgccttgc
     5641 ttagtgcgac cacttctcag ataaatattc cctagtagaa tatcctctcc tgcctctgtt
     5701 tgatagaggt tgccgcgtgt gctaaaggct gtctcaaaat tgccctcatc aacatacata
     5761 tctgtctgat ggccactctg gtcatagacg ataccacctt cacgcacagt gtatttatta
     5821 ttgtcaaaat cataaagatt taaataatac tgaccgttaa tcaattcata tcctgagcct
     5881 gctttagaag caacagcacc ctgtgactca ggaaagacat ctaccagcaa ataaagcttg
     5941 ccagaagcgt ctgttagcaa ggtggagtct attgaaaaag cagattgagt catgttggta
     6001 ttccaatcag ccaagctata ttgtgttgta aaataaggct gagttggcat atctaagacc
     6061 gtaatgttat tactccaggt tttgccatca tcatggctta tcctgacaac agttgcaaca
     6121 tctccccagt cattgtagtg cttctttctt gcatctgctg cggctatcaa ggttcctgat
     6181 ggcgttttga caacagaggg aatccgatat tcaaagaccc cttcatcata tttgtcccaa
     6241 acattcgtct tttcaccagt aactggtcga agggttggct gatgagcctt ggcaatatct
     6301 gtcagatcat acacatctgt atcaatcagc acctgatcaa ccagtccctt taacccccag
     6361 tgaaggaccg actcaccatc ataggtgcgt ttcaagcctc caattgttag cgtatcagca
     6421 gaagccttcc aaggtaattg cttcataaac ccagcaaagt cagcttcccc atataagtca
     6481 ccattcaagt aaatctttag cctagaccct gtaaagacat agctgatcgt ctgccagtcc
     6541 gagttcgtta ataaattaaa gcctgagcca acttttacaa tcggaacctc agctccttta
     6601 aattcaagac ctattttatt gtttttaggc tcgataaaga aagaggcgta ttcattagct
     6661 gatgcttgat ttgagatcga taacaaggcc aagggcgatg agcttctcac tgttgtatca
     6721 gcagtatcta gacggtatct gattgttaca gttccttggg ttaggttcat cacatcgtct
     6781 agcttaccaa gagcctcgtc atctgttacg gctgcttttt ctgctgttgc gtccaaaata
     6841 gcattgccta aatcaactaa aatggatgct tgatctgaga ttggctgatc tgagatatag
     6901 cttgcttcta tgcttgtata aacagctcgt ccgccttctg tggtgtattt gatctgataa
     6961 tgctctgcac ttcccaagat ctcctctggc gtaacccatt gccaattggc tggcagggct
     7021 actgtagata agggttctcc cttcttacca atcagacctt ctttaggtaa tacagttaaa
     7081 atagctactt ctcttgcaat cttagcagtt ggtgttactg ttgagcctaa atcagcattg
     7141 taaggaacag cactatagta aatgttataa ataccaggag ctagctcaga caaggctgac
     7201 aaatcatctc gaccagcagc ctgtaaagca gcattggtat ttccaccctt gttagtaaac
     7261 aagtattcat tttcaactga aaaatcaacc acatagcctt cctgatcagt ggttacagct
     7321 tgagctaaat caggactggt tccctctagc atggtcaaat ccttgacccc cttgagaact
     7381 ggctgtgagg cataataagc ttctgaggct gctttttgct cagcatcttg gtaataacgc
     7441 acataatcaa tcacaaaggc cgtctcatct gaagctagat agtagcctgc atttttactc
     7501 caattgcctc cagtagcaag gttaaactga aggtattgag gcttattaaa ggcagctgcg
     7561 gcagcctcta agcgatcatc accggttaaa tacatggtat tataaacaat cccatcaaca
     7621 taccattcaa tcttatccgg ataccaatta ataccaaaga tatggtagtc atcataaaag
     7681 tcatcactta atgtcagatt gccacccaat gctgttgggc tatagcttcc atctttgtct
     7741 gcatcaccct tgatatagta aaaatgaggg gtcccgtaaa ctgttttgtt gctttgatca
     7801 ccttcggcaa gctcaccctc atgctctccg ttaggagcac cgattagctc cataatgtca
     7861 agctcacctg tgcttggcca gccatagcct tgagttgacg caatatcacc atctaaggta
     7921 aaatcagccc ccaatgtcca aaaggctgga aaggctccct tacccttggg aagcttggcc
     7981 ctagcttcga tacgaccata taaaaattct tgcttgccaa ccgttcgtac gcttcctgaa
     8041 tcataaatga cctgacgtgc gcttgttcct cctctaggat tggcataacg gtcctcccca
     8101 taacgctctg tgacgtttaa aacaagattg ccattatcaa gatagacatt ctctgtgctg
     8161 tctgtgtagt gctgctgctc attcccgcga atacttccca attcatatcc ccagttctct
     8221 tggtttaacc gatctcctga aaactcatcc tgccaaatca attcataatc attttcctct
     8281 acgacactca cgttatcaat actagcagag gcagccaagg cttccggaga agaggcttcc
     8341 aaccatttga ctaagccaac aaaggtttct gaagtcgttg ctgtaaagga gagcttgata
     8401 tgtgaccaag taccgtctgt atctgtgagg ctgacctctt tgataacagg gccctgaaga
     8461 ttgtgattgg actctttagc ggtaaggtat aagccattat gaggtgtgtc agcttcaacc
     8521 ttcacatcag cctctagcgt ataggttttc ccaaccgttg tagacacctt ttgaaggata
     8581 tgctcatcta aagtgccgct tgttacctca gcatagctat taccattctc tgttgtgagg
     8641 actgaatgac ctccctctct atattgccac tgattcttat tggacacata atcattgtca
     8701 aaaccaccat tagccacctt attgagctca atcggagcgt tagacttctc ttcgtctgct
     8761 gtctgatcag cagcattgct ggtcacagca ttagctacta ctgcctcatc tactgtcgtc
     8821 tcctctgaga ctactaaggc ctcgctatct gtatctgtag cttgaggctc ctgctcatgg
     8881 cttatctctg ttactgctgc tttcgtaggc tgctgcaggc ttacctctga aacgtcatca
     8941 gcataaacag ccactggcag accagcagca agaccaatac ccacacacac tgaagcaaca
     9001 ccgacactaa gctttttgat ggcatatttt ctaatttgct cttttccgat aggattaaat
     9061 aacatgttta tttcctcact tatatataca tcatttttaa acacaatagc ttttcaaagg
     9121 cccatttagc ctaatccagt gctggtcagg ctaacgacct tgttataaaa acgctttcaa
     9181 ttcagcgctt aaaagaagat ataccagatg aaaccgatat atcctctcac aaagtgacta
     9241 acctgccttt tcaagctcat tatcagccat cttaacaaat ggaaggtaaa tcaggtttgc
     9301 caaggccaaa ttgacaagcg atagcacaat agcacgccaa tcaaaaccag ttgaaaagaa
     9361 gccatacaag acaggcggca ttacccaggt cacattttgc gtaacgggtg caaccaagcc
     9421 cagactagtt gcgatataag caacacttga cataacagca ggacaaacaa taaacggaat
     9481 aaacaacaaa ggatttaaaa cagttggtaa accatacatc actggctctc ctatattaaa
     9541 caatacagga gcaacaccta gcttagccac ctcacgatag tgttcatttt tagacttcca
     9601 gaaaatagca atcaagagcc ctaaggttgc ataccataca aagaacactc gtccaaagat
     9661 aaggaatcgc ctcatgcttt tgataagcct ccaaattagc caagagggca acaccaaata
     9721 ctccctccat atttggcgcc ataacattgc cgccatgaat cccaaagaac cagaaaaatt
     9781 gggtcaaaac agctaccaaa acaacagcaa taaagctttg tgataagccc aaaagtggga
     9841 tttgcaagac cttatagatc caatcaatca tcaaagaacc cgttagcttt tcaaagacaa
     9901 atgttaaaat agctacgcta tacaaggcgc aaaagcctgg tatgatagat aagaagggct
     9961 tggctacagc aggtggcaca ctatctggta atttaattgt ccaatttttt aacattaatt
    10021 tacaaaaaat aatagaggct aaaaagccaa tcataattgc tgtaaaataa ccattggagt
    10081 taatttgcgc accaggcaat aggcctgaga tggtcacatt aagtgagctg ccgctgacag
    10141 taacaccact gtccttaaaa gtcgtcacaa gatcaacacc cttgagacct gacgcgtcaa
    10201 tgctagaggt aacagaatcc ccaatcgcaa tcacaaaggc agctaaagaa accaaacctg
    10261 atgagagcgt atctgtctta taaagtttag cgacattaac ccctaagcaa tacacaaata
    10321 gcaaggacac aatcgaaatg cttcccttaa agacaaggtt gttgatggtt acccaccatt
    10381 ggaaggcctc tgtaatgcct tgcaagccaa attggtctgg aatatccact aaaaaggcat
    10441 tgatcaacag ggcaatagag cctgtcatca caaccggcat cgttgcaata aaagaatctc
    10501 gcaaggccac taaaaatcgt tgattaccaa tcttcgtagc aattggcagc agcttttgcg
    10561 aaagaaagtt catatagtta ttcattcata gctccttaaa acaatcataa aacagctaag
    10621 atagagcagt aaaggctctc tctaacagct tagccttcat ttttagtttg ctcgctcgcc
    10681 tgccatcttc tttccacatt aataataaac ggcaagtaaa gaagaatatc tagaataatt
    10741 aaaacaagct gtaggactga ggcttgccag ctgcccgttg ccaaaaatcc tgaaataaca
    10801 ggcggcatgg tccaccccgg atcagcatag gtgccaggta caatgccaga agcaaaggca
    10861 aaataagcga caaacaaatt cataacaggt gctagtacaa aaggaataac tgtcaataga
    10921 tttaaaacaa ccggtaagcc aaacatggtc ggctcgttaa tgttgaaaaa ccctggaatc
    10981 aaggtcaatg gtgacaagac ctttgcctgc tgactagcct tgcgacgacg tgctaaccag
    11041 gctaaagcca acaccaagcc aatggttgca ccagctccgc cgataaaaac aaagttatcc
    11101 ataaagacag acgtaaagac atgcggcaat tcctgaccag ccttatgagc tgccatattt
    11161 tcagtcaagt tagataacca gatcggcttc ataataggat tgtttaggac atttccacca
    11221 tgcacaccac agaaccataa aaagccatta agaagaacaa cgataaaatt accaaataag
    11281 gtacttccca gcaagccaaa tggaactcct agtacggact taacaatgtc atggacattt
    11341 ggcaggctaa aatgatccaa gaaagcataa acagcaagcc aaaacacaat aatcaccgct
    11401 ccaggaataa tggcgctaaa gctttttgat actgcaggcg gcacaccctc aggcatctta
    11461 atccgaatat cctttttcat aaaccattga taagcatagc catttaccaa tcccaaaaca
    11521 atggcaacaa acaagccgcc tgatgaaagg taagaaggcg caatacccgc tacctcaccc
    11581 aaggctttac cagattcatt gacaaatgaa acagtaaatg gggtcactgt taaaaaggca
    11641 gagatattaa taatcccagc agaaatcccg tctgccttat actgcttagc caagctataa
    11701 gaaatcccaa aggccgcaac caaggcaatc agattaaagc tcgaatctac tcccttccac
    11761 agataggtag agacaccaat ctcaccaagc caagcttccc aaccaggaat cggcaggcta
    11821 gcaatcacca ttaaaaagga cccaatcaaa atcaagggca tagcgtaggt gatcccatca
    11881 cgaatagcaa taagaaagcg attgcttcct aggcgaccag caactggaac aagcttttgc
    11941 tggataaaat cttcaaattt agtcattgtt acctccttgt gacgttaacc tttcataaat
    12001 agatactagc tcccttgcca aatcaacaaa ggtaatacta gtcatcaaat gatcctgacc
    12061 atgaactaat agtaggctta ctggtgtagc atttccccgt gcctcttgag ttagcatatc
    12121 tgtttgtgca tgatgggcct gcaccaatgc cttatcggcc tgctttagac tttcctgagc
    12181 ttgattgagc tctccctttt tagcaaaagc aatcgcctcc atcgcaagcg acttggcact
    12241 accaccatgc atgatcaggc ccataatcgt ctctagctgc ttatcttcca tgaccaccac
    12301 ctatttcatc aaactttcag ctaaggcaat aaccttatca ccattcatca taccgtaatc
    12361 aaccattggc acaaccgcca ctggaatgtc cttttctgcc aagctttctt gaaatgctga
    12421 caattgataa gcaacctgtg gccctaataa caccacatca acaggatggc ttagagcgta
    12481 atcctctgcc tcagtcaatg gcaatgcaaa aatatctgcc tcaagccccc gattgtcagc
    12541 agccttttcc atctttgtca ctaatagact ggtactcata cccgctgcac aggccaacat
    12601 aatttgtttt ttactcatga tcttctcctt tatcccaaat cctaacgtcg aatagagcgc
    12661 gacattctca caatggtatg tctttttcct cggatagcgt cactaagagc aaagatattt
    12721 tccactggcg caatcccgct atagccagca tctccgatat gatgaatatc gacaccacag
    12781 attttattgc gaatagcaat gtctcgaacg atcgtagtat ctgacccttc ctgactcgtt
    12841 ccaatagctg acataactag agcatcgtga gcatgcacct cctcaacaat agctctaagg
    12901 tcaccctctg taaagccagg aactgtccca acagcaggaa ctaaaatcac atcagcccca
    12961 gcctcgataa accgccgaac agtttctaag tcaatcaccg cttcattaga gccagcagca
    13021 tgcatctttc cagcaataat caagcctgaa aaatagtgct tggcctgttg aatagctctt
    13081 tcaatctgat tattgctaac accagtacct ggatttcctg tcaagcaaac aaagtcaaag
    13141 cccaaggctt caatctcttg aaaggtctta gctgtcgcct gtcgcccttc tactagctcc
    13201 aagcgctttt cagtcatgtc aacgtccaaa tcaattggtt ctaaattaac accaattgga
    13261 cgccccacca gacgacgcag ctctaaaata ggctgatcag tagcaggtag accagatatt
    13321 tgaacatcaa agacatctac acaattcagc aaaatcaaat cagcactaaa ggctgcggca
    13381 acctcagcgt tcgtaaggtc atctccagtc caagagggtc ttggcgctac attttctgag
    13441 acaatggtac gtccctcgct tgccttaatg gcttgcttta gctctaacga tgttaactgt
    13501 agcatttctg agctactagc actcaataat cgtgttttca tcgcttctcc ttt
//
LOCUS       DARYXW010000055        13130 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.055, whole genome shotgun sequence.
ACCESSION   DARYXW010000055 DARYXW010000000
VERSION     DARYXW010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13130)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13130)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13130
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.055"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(241..489)
                     /locus_tag="TV191_001307"
     CDS             complement(241..489)
                     /locus_tag="TV191_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEL1507814.1"
                     /translation="MEVKTLANIKSAIKRAELNVKANEKNSAQKSAMRTAIKAFEANP
                     SEELFRAASSSIDKAQSKGLIHKNKASRDKARLAAKLS"
     gene            complement(543..1463)
                     /locus_tag="TV191_001308"
     CDS             complement(543..1463)
                     /locus_tag="TV191_001308"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEL1507815.1"
                     /translation="MSNEFITFEKISRKSWKQLHQKSKPLLTQEELTSITSLNDNIDI
                     NDVVEVYLPLIHLIQVYKIAQENLSFSKSLFLKKDIQQRPFIIGISGSVAVGKSTTSR
                     LLQLLLARTHKTSTVELVTTDGFLYPNSTLIKNNMLNRKGFPESYNMELLLNFLDTVK
                     GGQTASAPVYSHEIYDIVPDQQQTFTNPDFLIIEGINVFQNQQNNRLYMSDYFDFSIY
                     IDADSHHIEQWYLERFLSLLELAKHDPANYYTRYTSLPQNEAIAFAKKVWKTINLENL
                     EKFIEPTRNRAELILHKAADHKIDEIYLKK"
     gene            1697..2326
                     /locus_tag="TV191_001309"
     CDS             1697..2326
                     /locus_tag="TV191_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1507816.1"
                     /translation="MKKHRKKIGKHMTKMYYDENPDSAHDIHQLTVNLLGQSFTFLTD
                     SGVFSKRMVDFGSQVLLNTLDFQEGDRLLDLGCGYGPLGLSLAKAQGVEATLVDINHR
                     AVGLAKQNAESNQVEATIFQSNLYDGVTGTFEHIISNPPIRAGKKVVHEIIEKSIDFL
                     TKGGDLTVVIQKKQGAPSAKDKMEAVFGNVTILKREKGYYILRSIKERN"
     gene            2425..3702
                     /locus_tag="TV191_001310"
     CDS             2425..3702
                     /locus_tag="TV191_001310"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEL1507817.1"
                     /translation="MRAVDLIQKKRDGKELSTEEIQWLINGYANGTVPDYQMSAFAMA
                     IYFKGMSTRETRDLTMSMVETGEQIDLSAIAGIKTDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTLDKLESIKGFQIGRTQEEFIKQVQEIGLSVIGQSDKLVKA
                     DKLLYALRDVTATVDIVPLIASSVMSKKIAAGADSILLDVTVGDGAFMKTIEDAEKLS
                     RLMVDLGKEVGRQTVAVITDMSQPLGRAIGNRLEVLEAIDIMKGKGRKDITHFICELA
                     QIMLELAGAQHSLEDIHHHLVGGAALKKLEEMVVYQGGDLEDLYRPSQAAVQTEVFAS
                     EDGYITALPALEFGLFAMRLGAGRAVKTDSLDYETGIVFDKKVGDAVAKGERIAVVFS
                     QEALDEKMLTEFEKNVKIGAEHLEANEIIKIIS"
     gene            3716..4378
                     /gene="deoC"
                     /locus_tag="TV191_001311"
     CDS             3716..4378
                     /gene="deoC"
                     /locus_tag="TV191_001311"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEL1507818.1"
                     /translation="MNINKYIDHTLLKADSVQSQLDQLIEEAKAYDFASVCVNPCWVA
                     YAAKALKGTDVKVCTVVGFPLGATTSATKAFETKDAIENGADEIDMVINIGLLKQGDY
                     QAVEDDMRAVVEASGDKLVKVIIEACLLTDDEKVKACQLAVNAGVDFVKTSTGFSTGG
                     ATVSDVKLMRQTVGPDIGVKAAGGARSLEDALAFVEAGATRIGTSAGVTIMKGEVANG
                     GY"
     gene            4365..4754
                     /locus_tag="TV191_001312"
     CDS             4365..4754
                     /locus_tag="TV191_001312"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEL1507819.1"
                     /translation="MEATDLVSLAIEASKRAYVPYSHFPIGAALKTKDGTIYTGNNIE
                     NASFGLTNCGERTAIFKAVSEGHQQLLEIAIYGETDEPISPCGACRQVMAEFFEATAP
                     VTLIAKDGRTMRTTVGELLPYSFTDLS"
     gene            4845..5897
                     /locus_tag="TV191_001313"
     CDS             4845..5897
                     /locus_tag="TV191_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEL1507820.1"
                     /translation="MNKKFIGVGLASVALLGLVGCGNRNASKGSGDAKTDLKVAVVTD
                     TGGVDDKSFNQSAWEGLQAWGKDNGLTKGSGFDYFQSTNESEYATNIDTAVSSGYEVV
                     YGIGFALKDAISKAADDNNKVQFVIIDDVIEGKDNVASVTFADNEAAYLAGIAAAMTT
                     KTKTVGFVGGMEGTVVTRFEKGFEAGVKSVDDSIKIKVDYAGSFGDAAKGKTIAAAQY
                     AAGADVIYQVAGGTGAGVFNEARTINEKRDEADKVWVIGVDRDQNEEGKYTSKDGKSS
                     NFVLASTIKGVGKAVQLINKQAADKKFPAGKTTVYGLKDGGVEIATTNLSKDVIKAIE
                     EAKEKIKSGDVKVPEK"
     gene            6024..7556
                     /locus_tag="TV191_001314"
     CDS             6024..7556
                     /locus_tag="TV191_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1507821.1"
                     /translation="MAQHVIEMKEITKKFGDFVANDHINLNVRKGEIHALLGENGAGK
                     STLMNMLAGLLEPTSGNIVINGQPVVIDSPSKSARLGIGMVHQHFMLVEAFTVAENII
                     LGNEVVKNGCLDLKKASKDIKELSEKYGLAVDPTAKIADISVGAQQRVEILKTLYRGA
                     DILIFDEPTAVLTPAEIQELMEIMRNLVKEGKSIILITHKLDEIRAVADRVTVIRRGK
                     SIQTVDVAGATSQDLAEMMVGRSVSFTTAKKAAEPKGVVLSIKNLEVDENRGIPAVKG
                     LSLDVRAGEIVGIAGIDGNGQSGLIQAITGLRKTRSGSITIKGQEVVHLSSRKITELS
                     VGHVPEDRHRDGLVLDLSLAENTALQTYYKEPLSKNGILNYNTINDYARRLMKEFDVR
                     GANELVPARGFSGGNQQKAIIAREVDRNPDLLIVSQPTRGLDVGAIEYIHKRLIEERD
                     KGKAILVVSFELDEILNLSDRIAVIHDGKIQGIVLPQDTNKQELGILMAGGSIDKEES
                     HV"
     gene            7549..8613
                     /locus_tag="TV191_001315"
     CDS             7549..8613
                     /locus_tag="TV191_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1507822.1"
                     /translation="MSKNAQKIAVPMISILLGFLLGAIVMFIFGYDPIWGYEGLFQVA
                     FGSIKNIGEIFRAMGPLILIALGFTVASRAGFFNVGLSGQALAGWIAAGWFALVNPNM
                     PRPLLILMTVLIGMVAGGIAGAIPGILRAYLGTSEVIVTIMMNYIILYVGNAIIQRGY
                     PESVKQSIDSTIQVSDNASYQSQWLSDLTNNSRINIGIFFALIAIAVIWFLLNKTTLG
                     FEIRSVGLNPHASEYAGMSLKRTIILSMIISGALAGLGGVVEGLGTFENVFVQGSSLA
                     IGFDGMAVSLLAANSPIGIFFSSFLFGVLSIGAPGMNIAGIPPELVKVVTASIIFFVG
                     AHYLIERYIIRPKKLVKGGK"
     gene            8615..9571
                     /locus_tag="TV191_001316"
     CDS             8615..9571
                     /locus_tag="TV191_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002268043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1507823.1"
                     /translation="MSLVTIFALLVSSMLIYATPLIFTSIGGTFSERAGVVNVGLEGI
                     MVMGGGSGIVFNLEFAHIFGKATPWLAVLVGGVVGLIFSLIHALATINFRADHIVSGT
                     VLNLLAPSLAIFLVKVMYGKGQTDNIQQSFGKFDFPILSKIPVLGDIFFRNTSLVGYL
                     AVAFSFLAWFVLYKTRFGLRLRSVGEHPQAADTLGINVYLMKYYGVMISGFLGGIGGA
                     VYAQSISVNFAVTTILGPGFIALAAMIFGKWNPVGAMLSSLFFGLSQSLAVIGAQLPV
                     LEKIPTVYLQIAPYLLTIIILAAFFGQAVAPKADGVNYIKSK"
     gene            complement(9609..10865)
                     /locus_tag="TV191_001317"
     CDS             complement(9609..10865)
                     /locus_tag="TV191_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEL1507824.1"
                     /translation="MEHLNNTTQLIGIKDKHITLTKAIQHDTHIEVIATLDYNPPKCK
                     LCAGKQIKYDFQKPSKIPFIEIGGFPSLIRLKKRRFQCKSCRKVTVSETTLVKKNCQI
                     SEIVRQKIAQLLLNRKALTHIASKLAISTSTVYRKLKQYHFREDYANLPEVLSWDEFS
                     YQKGKLAFIAQDFNTKKIITILDNRRQTTIRNHFFKYSKEARNKVKVVTVDMSGSYIP
                     LIKILFPKAKIVLDRFHIVQHINRALKQIRSDIMKPFDKKSLKYRALKYYWKLIQKDS
                     RKRSLKPFYSRTFRQTLTPRECLNKIFSLVPELNSYYDLYQLLLFHLQEKNAKHFFGL
                     IHDTLPHLNQTFKTALNTFSRYQDYITNAIQLPYSNAKLEATNKLIKDIKRNAFGFRN
                     FDNFKKRIYLALNITKEKTTFVFSRA"
     gene            complement(11385..13100)
                     /locus_tag="TV191_001318"
     CDS             complement(11385..13100)
                     /locus_tag="TV191_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEL1507825.1"
                     /translation="MTYTENYQKWLDIPDLPAYLRDELLSMDEKTKEDAFYTNLEFGT
                     AGMRGYIGAGTNRINIFVVRQATEGLAALVESKGEAAKKAGVAIAYDSRHFSPEFAFE
                     SAQVLAAHGIKSYVFESLRPTPELSFAVRHLGAFAGIMVTASHNPAPFNGYKVYGSDG
                     GQMPPADADALTDYIRAIDNPFAIRLADLEKAKANGLIEVIGEAVDLAYLEEVKKVNI
                     NQDLINDYGRDMKIVYTPLHGTGEMLARRALAQAGFKSVQVVEVQAKPDPDFSTVKSP
                     NPESQEAFTLAEELGRQVDADVLVATDPDADRLGVEIRQADGSYRNLSGNQIGALIAK
                     YILEAHQQAGTLPNNAALAKSIVSTELVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNYTYMFGFEESFGYLIKPFVRDKDAIQAVLLVAEIAAYYRSRGLTLADGIDDIYKE
                     YGYFAEKTISVTLSGVDGAAEIKQIMDKFRKHAPAQFNHTDIVLTEDFLSQTATHKAG
                     QTQLTTPPSNVLKYTLADDSWFAVRPSGTEPKIKFYIATVGDTLALAEEKIANIESEI
                     NAFVS"
BASE COUNT         3753 a         2316 c         3053 g         4008 t
ORIGIN      
        1 gcgatcaaga cgcagaacag gggctatagc agcctgatgt gagacaggaa ggacttactg
       61 tcctaccagc tacagtcact acactgctag agcttgcggt gtgagcagca gtaagaggca
      121 aaggcgttac cccagaggga ttgatggatc accatcacta gtttggagcc attagctgtg
      181 ccaaaggttt tctaaagcca aaaagaaaaa actccgattg gagttttcat tggttatgta
      241 ttagctaagc tttgcagcaa gacgtgcttt atcgcggctt gctttatttt tatgaatcaa
      301 accttttgat tgggctttat caatgcttga agaagcagcg cggaaaagct cttcagatgg
      361 gttagcttca aatgccttga tagcagtacg catagctgat ttttgtgctg aatttttttc
      421 gtttgcttta acgttaagct cagcgcgttt aatagctgat ttaatatttg ccaatgtttt
      481 cacctccaaa ttaatctaac tacaccatta tatagaaaat ataggtgttt ggcaagcact
      541 tatcactttt tgagataaat ttcatcaatt ttatggtctg cagctttatg aagaatgagc
      601 tcagctcgat tgcgtgtagg ctcaataaac ttttccagat tttctaggtt aattgttttc
      661 cagacttttt ttgcaaaggc aatggcttca ttttgtggca atgaggtata tctagtgtaa
      721 tagttagccg gatcatgctt agccagctct aaaaggctta agaaccgttc caaataccat
      781 tgctcaatat gatggctatc tgcgtcaata taaattgaaa aatcaaaata atcactcata
      841 tacaatcgat tattctgttg attttgaaaa acattaatcc cttcgatgat gaggaagtca
      901 ggattggtaa aggtttgctg ctgatcagga acgatatcat aaatctcatg cgagtaaaca
      961 ggggctgatg cggtttgtcc tcccttgaca gtatccagaa agtttaacaa tagctccata
     1021 ttataggatt ctgggaagcc ctttcgattc agcatattgt ttttgatcag tgtgctatta
     1081 gggtacaaaa aaccatctgt tgtgaccaac tcaacagtgc tggtcttgtg tgtgcgcgcc
     1141 aaaagaagct gcaataacct gctagttgtg gacttaccga cggcaactga gccagaaatc
     1201 ccaataataa agggtctttg ctgaatatct ttttttagaa agaggctttt agaaaaagac
     1261 aggttttctt gagcgatttt atagacttga atgagatgaa tcaagggaag gtaaacctca
     1321 acaacgtcgt tgatatcaat attatcattc aaactggtga tgctagtaag ctcctcttga
     1381 gtcaataagg gcttgctttt ttgatgtaat tgcttccagg attttctgga aattttttca
     1441 aaagtaataa attcgtttga catagttact cctactaatt ggcagtgctt acattataac
     1501 atgtcaataa aaaaattgaa aaatgtttcg tctgaaattc ttaaaaaaac actgaaaaac
     1561 cctataaaaa tcgaacaatt ttagcctaac aattggctaa tataaagtta atcggtcaat
     1621 gttcggaata tatggttcga taaacgaaaa accaagaaaa acaaacgtct tgtaaaccat
     1681 ttcaaagtgt gatagaatga aaaagcatcg aaaaaagata ggaaaacaca tgacaaaaat
     1741 gtattatgat gaaaatccag atagtgctca tgatatccat caattgacgg tcaatttgtt
     1801 aggacagtcc tttacttttt tgacagattc tggtgttttc tcaaaaagaa tggttgattt
     1861 tggaagtcag gtcctgctca acacattaga ttttcaagaa ggtgatcgtc tgcttgactt
     1921 gggctgcggc tatgggccgc taggacttag cttggcaaag gctcaaggtg ttgaggcgac
     1981 tctagtagat attaatcatc gcgctgttgg cttagctaag cagaatgctg agagtaatca
     2041 ggttgaggcg accatttttc aatcaaacct ctatgacggt gtgacaggga catttgagca
     2101 catcattagt aacccaccta ttagggcagg gaaaaaagtg gttcatgaga ttattgaaaa
     2161 gagtattgat tttttaacta aaggcggtga tttgacagtc gttatccaaa agaagcaggg
     2221 agcaccaagt gctaaagaca aaatggaggc cgtttttggg aatgtgacta ttctcaaaag
     2281 agaaaagggt tactacattt taagaagtat taaggaaagg aattgagctc aagtgtaaaa
     2341 agtggtatta aaaagcatag cggtatttta gtaagagttg ccttctaata tcactatttt
     2401 ctcagagctt ttggtatctt gttgatgaga gcagttgatt taatccaaaa aaagcgtgat
     2461 ggtaaagagc tatctaccga agagatccag tggctgatta atggttatgc caatggtact
     2521 gtgccagatt atcaaatgtc ggcttttgca atggcgatct atttcaaggg aatgtctaca
     2581 cgagaaactc gcgatttgac catgagtatg gttgagacag gtgagcagat tgatttgtca
     2641 gctatagctg gtatcaagac ggacaagcac tcaacaggtg gtgttggtga taaggtgaca
     2701 ctcatcttag ctcctctagt tgctagcttt ggcgttcctg tagcgaaaat gagtggacgc
     2761 ggcttaggcc acaccggtgg aacgcttgat aagctagaat ctatcaaggg ctttcagatt
     2821 ggtcggaccc aagaggaatt tatcaagcag gtacaagaga tcggactttc agttattgga
     2881 caatcagata agcttgtgaa ggcagataag ctgctttatg ctcttcgtga tgtgacggca
     2941 accgttgata ttgttccttt gattgcaagc tctgttatga gtaagaaaat tgctgctggc
     3001 gctgatagta ttttgctaga tgttaccgtt ggtgacggtg cctttatgaa gactattgaa
     3061 gatgctgaga agctgtctag actgatggtt gaccttggta aggaggttgg gcgtcagaca
     3121 gtggctgtca ttacagatat gagtcagcct cttggtcgtg ctatcggtaa tcgcttagag
     3181 gtgctagagg caattgatat catgaaaggc aagggacgca aggatattac tcactttatt
     3241 tgtgagctag ctcagattat gctggagctt gctggtgctc aacactctct tgaggatatt
     3301 caccatcatt tggttggcgg agcagcctta aaaaaattag aagagatggt tgtttatcaa
     3361 ggaggtgatc ttgaggacct ttatcgtcca tcacaggcgg ctgttcaaac agaggttttt
     3421 gcgtcagaag atggttacat cacagcattg cctgctcttg agtttggatt gtttgcaatg
     3481 aggctgggtg ctggtagagc agtcaaaaca gatagtctgg attatgaaac agggattgtc
     3541 tttgacaaga aggttggtga cgctgtcgct aagggagagc gcattgcagt tgtcttttca
     3601 caggaagccc tagacgaaaa aatgcttaca gaatttgaaa aaaatgttaa aataggggcg
     3661 gaacacctag aggctaacga aattatcaaa atcatttcct aaggaggagt ataacatgaa
     3721 tattaacaag tatattgacc acacactact aaaagctgac agcgttcaat cgcagcttga
     3781 ccaattaatt gaggaggcta aagcctatga ctttgctagc gtttgcgtca acccttgctg
     3841 ggtagcctat gctgcaaagg ctttaaaggg aacagatgtt aaggtttgta cagttgttgg
     3901 ttttccttta ggtgcaacta cctcagcaac aaaggccttt gaaacaaagg acgctattga
     3961 aaatggtgct gatgagattg atatggttat caatattggt ctgttaaagc agggtgacta
     4021 ccaagctgtt gaagatgata tgcgtgcagt ggtagaggct agcggagaca aattagtcaa
     4081 ggtgattatc gaggcttgcc tcttgactga tgatgaaaag gttaaggctt gtcagttggc
     4141 ggtaaatgca ggtgttgact ttgtgaagac ctctactggt ttttcaactg gcggtgcaac
     4201 cgtttctgat gtcaagctaa tgcgtcaaac agttggtcca gacattggcg taaaggcagc
     4261 tggtggtgct cgttctctag aggacgcttt agcttttgtc gaagcaggag ctacacgtat
     4321 tggaacttct gcaggggtaa ctattatgaa aggtgaagtt gccaatggag gctactgatt
     4381 tagtttcgtt agccattgaa gctagtaaaa gggcttatgt gccttactca catttcccga
     4441 tcggagctgc tttaaagaca aaggacggaa caatctatac tggcaataat atcgagaatg
     4501 ccagctttgg cttgaccaat tgtggggagc gaacagctat ttttaaggct gtttctgagg
     4561 gacatcagca gcttttagaa attgccattt atggagagac tgatgagcca atctctcctt
     4621 gtggagcctg tcgtcaggtc atggcagaat tttttgaagc cactgctcca gtaacgctaa
     4681 ttgctaagga cggtcgtacc atgcgcacaa ctgttggcga gttacttcct tattcgttta
     4741 cagatttatc gtaatctggc ttaattttgt tatctagcca ttaggcttta tatttacttt
     4801 cggcaattgg tttgctagaa atatttttag gagggttcat attcatgaac aagaaattta
     4861 ttggtgttgg tttagcttct gtagctttat taggtttagt tggttgtggt aatcgtaacg
     4921 cttcaaaggg atctggtgat gctaaaacag atttgaaggt agcagtggtt actgacactg
     4981 gtggtgttga tgataagtca tttaaccaat cagcttggga aggcttgcag gcttggggta
     5041 aggacaatgg actaacaaag ggttcaggct ttgattactt ccaatctaca aacgagtctg
     5101 aatatgcaac taacattgat acagcagttt ctagtggtta tgaggttgtt tatggtatcg
     5161 gatttgcctt gaaggatgca atcagtaagg ctgctgatga caacaacaaa gtacaatttg
     5221 ttatcattga tgatgttatc gaaggcaaag acaatgttgc tagcgtaaca tttgctgata
     5281 acgaagctgc ttaccttgca ggtattgcgg cagctatgac tacaaaaaca aaaacagttg
     5341 gttttgtagg tggtatggaa ggaacagttg ttacacgctt tgaaaaaggc tttgaggcag
     5401 gcgttaagtc tgttgatgac tcaatcaaga tcaaggtgga ctacgctgga tcatttggag
     5461 atgccgctaa gggtaagaca attgcagcag cgcaatacgc agcaggtgct gatgttatct
     5521 atcaggtagc tggtggaaca ggtgcgggtg tcttcaacga agcaagaaca attaacgaaa
     5581 aacgtgacga agctgataag gtttgggtaa ttggtgttga ccgcgaccaa aacgaagaag
     5641 gtaaatatac atctaaggat ggcaaatcat ctaactttgt acttgcatct actataaaag
     5701 gtgttggtaa ggctgttcaa ttgatcaata agcaggcagc agataagaaa ttccctgcag
     5761 gtaaaacaac tgtttatggt ctgaaggacg gtggtgttga gattgccaca acaaatcttt
     5821 ctaaagacgt tatcaaagcc atcgaagaag cgaaagaaaa aattaaatct ggtgacgtaa
     5881 aagttcctga aaagtagtta ctggaaaaga gcgaccttcg tcggtcgccc tttttagagt
     5941 ggaacacctt ttgcttcagt aaaggttgtg acaaatggct ggctttactg aaacaaaaga
     6001 ttaaattgaa aggaaataat cctatggcac agcatgtcat tgaaatgaaa gagattacaa
     6061 aaaaatttgg tgattttgtt gcgaatgacc atattaattt gaatgtcaga aaaggcgaaa
     6121 ttcatgcatt gttaggagag aatggtgcag gtaaatcaac gttaatgaat atgttagctg
     6181 ggcttttaga gccaactagt ggaaacattg tcattaacgg tcagcctgtt gttattgact
     6241 ctccttccaa atctgctaga ttgggtattg gaatggtaca ccagcacttt atgctagtag
     6301 aagcttttac agttgctgag aatatcattt taggaaatga agttgtcaaa aacggttgtc
     6361 ttgatttaaa aaaggccagc aaggacatta aagagctttc tgagaaatat ggtttagctg
     6421 ttgatcctac tgccaagatt gctgatattt ctgtaggggc acagcagcgt gttgaaatct
     6481 taaagacctt atatcgtggt gcagatattc ttatttttga tgagccaaca gctgttttaa
     6541 cgcctgctga aatacaagag ctcatggaaa tcatgcgtaa ccttgttaag gaaggcaaat
     6601 ccattatttt gattactcat aagctggacg aaattagagc agttgctgat agagtcactg
     6661 ttattcgacg tgggaaaagt attcaaacag tagatgtagc aggtgcaacc tctcaggact
     6721 tggctgaaat gatggttggg cgttcagttt cctttacaac agctaaaaag gcagcagagc
     6781 caaaaggggt ggtgctgtcg atcaagaatt tagaggtcga tgaaaatcgt ggaatcccag
     6841 cagtaaaggg gctttctctt gacgttagag ctggtgaaat tgtggggatt gcagggattg
     6901 atggtaatgg tcagtcaggg ctgattcagg ccattacagg cttgagaaag actagatctg
     6961 gtagcattac aatcaaaggt caggaggttg ttcatttaag ctcccgtaaa atcacagagc
     7021 tatcagtggg gcatgtgcct gaggaccgtc atagagatgg cttagtgctg gacctttcct
     7081 tggctgaaaa tactgccctt cagacctatt ataaagagcc actaagtaag aacggtattt
     7141 taaattacaa tacaatcaat gattatgctc gtagactgat gaaggaattt gacgttcgtg
     7201 gtgccaatga attggttcca gctcgtggat tttctggcgg taaccaacaa aaggctatca
     7261 ttgcacgtga ggttgaccgt aaccctgatt tattgattgt cagtcagcca actcgcggct
     7321 tggacgttgg tgctattgag tacattcata agcgtttgat tgaagagcgt gacaaaggca
     7381 aggccatcct cgttgttagc tttgagcttg acgaaatctt gaatttatct gaccgtattg
     7441 cagttattca tgacggtaaa attcaaggca ttgtgttgcc tcaagatacc aataagcaag
     7501 aattgggaat tttgatggct ggtggttcca ttgataagga ggagagtcat gtctaaaaat
     7561 gcacaaaaga ttgctgtgcc aatgatttct atcttgttag gattcttact tggcgctatt
     7621 gtcatgttta tctttggcta tgatccaatt tggggctatg agggcctatt tcaggtagcc
     7681 tttggtagta tcaaaaatat tggtgaaatc ttcagagcga tgggaccact aatcctgatt
     7741 gcacttggtt ttaccgttgc tagccgtgcc ggcttcttta atgtcgggct gtcaggtcaa
     7801 gctttggctg gttggattgc tgcgggctgg tttgctcttg tcaatcctaa tatgcctcgt
     7861 ccgcttttaa ttctgatgac tgtcttgatt ggtatggttg ccggcggaat tgctggcgct
     7921 attccaggta ttttgcgagc ttatcttggt acgagtgaag ttattgttac cattatgatg
     7981 aattatatta ttctgtatgt cggtaacgct atcattcaaa gaggctaccc tgaaagtgtt
     8041 aagcaaagta ttgattcaac catacaggtc agtgataatg ccagctatca aagtcaatgg
     8101 ctgtcagatt taaccaataa ttctcgtatt aatatcggta tcttttttgc gcttattgca
     8161 attgcagtta tttggttctt actaaacaaa acaaccctcg gatttgaaat tcgttcagta
     8221 ggtcttaatc cacatgcttc agaatatgca ggtatgtcct taaagcgtac gattatccta
     8281 tcaatgatca tttcaggtgc tttagcaggc ttgggaggag ttgttgaagg cttgggaacc
     8341 tttgagaatg tttttgtaca gggaagctct ctagcaattg gttttgacgg tatggctgtt
     8401 agcttgcttg ctgccaattc accgattggt atcttcttct catcattcct atttggggtg
     8461 ttgagcatag gtgctcctgg tatgaatatc gcaggaattc caccagaatt ggtaaaagta
     8521 gtgactgcct caattatctt ctttgtaggt gctcactacc ttatcgaacg ctatattatc
     8581 aggcctaaaa aactagtaaa gggaggtaaa taagatgagt ttagttacta tttttgcttt
     8641 attggtttca tcaatgctta tctatgctac acctcttatt tttacaagta ttggtggtac
     8701 cttctcagaa cgagctggtg ttgtcaatgt cggccttgaa ggcattatgg tcatgggggg
     8761 gggttcaggc attgtcttta atcttgaatt tgctcatatc tttggtaaag ctactccctg
     8821 gcttgcagtt ttggtgggag gagttgttgg attgatcttt tcattgatcc atgcgcttgc
     8881 aacgattaac tttagggcag atcacattgt cagtggtaca gtgctaaatc tgctggcacc
     8941 atcgcttgcc attttcttag ttaaggtgat gtacggtaag gggcaaactg ataatatcca
     9001 gcaatcattc ggtaagtttg attttccgat tctctcaaaa attccagttc ttggagatat
     9061 attctttaga aatactagct tagttgggta tttagctgtt gccttttctt tcctagcttg
     9121 gtttgtgctt tacaaaacaa gatttgggtt gcgtttgcgc tctgtaggtg aacaccctca
     9181 agcagctgat acacttggta ttaacgttta cctcatgaaa tattatgggg ttatgatctc
     9241 tggttttctt gggggtattg gtggagctgt ctatgcacaa tccatctctg ttaacttcgc
     9301 agtgacaacc attttaggac ctggatttat tgcccttgcc gctatgattt ttggtaagtg
     9361 gaatccggta ggtgctatgc tatctagctt gttctttgga ttatcacaaa gcttagcagt
     9421 tattggggca caattaccag tattggaaaa aatcccaacg gtttaccttc aaattgcgcc
     9481 atacctattg accatcatca ttttggctgc tttctttgga caagcagtgg ctccaaaggc
     9541 agacggtgtt aattacatca aatcaaaata aaaaaagctc aatgtcaact gtagtgggtg
     9601 actgatagct aagcacgaga gaagacgaat gtcgtcttct cttttgtgat attcaaagcg
     9661 aggtagatac gttttttaaa gttgtcaaag ttccgaaatc cgaaagcatt gcgcttgata
     9721 tctttgataa gtttgttagt ggcttctaac ttagcgttag aataaggcag ttgaatggca
     9781 ttggtgatgt aatcttggta gcgactaaag gtatttagag ctgttttaaa agtctgatta
     9841 agatgtggta gtgtgtcatg aattaaacca aagaaatgct tggcattctt ttcttgcagg
     9901 tgaaaaagga gcagctggta caggtcataa taagagttta actcaggcac tagtgagaag
     9961 atcttattga gacattctct aggagttaag gtttgtctga aggtgcggga atagaaaggc
    10021 ttaagagacc gttttctgct atccttttga ataagcttcc agtagtactt aagagctcta
    10081 tatttaagag acttcttgtc aaatggtttc atgatgtcac tacgtatttg cttgagagct
    10141 ctattgatgt gctggacaat gtgaaaacga tcgagaacga ttttagcctt aggaaataga
    10201 attttaatga gaggaatata acttccagac atatcgacag tgacgacttt caccttgttt
    10261 ctagcctctt tagagtactt aaagaaatga tttcggatgg ttgtttgacg tctattatca
    10321 agaatggtaa tgattttctt agtgttaaaa tcctgagcaa tgaaggctaa tttacctttc
    10381 tgataagaga actcatccca agagagaact tctggcaaat tggcgtaatc ctctcggaaa
    10441 tgatactgct taagcttgcg atagacggta gaagtggaga tagcgagctt agaagcgata
    10501 tgggtgagag cctttctgtt gagtaaaagc tgagcgattt tctgtctcac tatctcagaa
    10561 atttggcaat ttttcttaac cagggtagtt tcagatacag tgacttttcg acaggatttg
    10621 cattgaaacc ttcttttttt caaacgaatg agactaggaa agcctccaat ttcgataaag
    10681 ggaattttag agggcttctg gaagtcgtat ttgatttgtt ttcccgcaca cagtttacat
    10741 ttaggagggt tatagtctag tgtagcgatg acttcaatat gagtatcatg ctggatagct
    10801 ttagtcaagg tgatatgttt gtctttgatt ccaatgagtt gtgtggtatt attgaggtgt
    10861 tccataagat accttctaaa tgatagttta gtcgcttttc atgataagtc ttatgggact
    10921 tttttgatac tcaaaaagcc ctataatctc cacagtagcc ttacccacta cagaaattat
    10981 agagccatct tagaacactg gacttgttcg ctttttaatg aattaaattt agtagatcct
    11041 ttaaaggcat gctatcaagc tttttatcct tgacttttgt ttagcaagtg aagtgttcac
    11101 aaaagctagc taaaacactg agctgacaat gtagagaatg gctcgttttg acaaggttag
    11161 agtgcttttt gctgtatggt ttttaatcca cgcacctgaa aaagaaagga caggacctgt
    11221 gcgagcttac ttgtggttag taggtttcaa ttcatgctcc caaaaaggaa gcaacgcaac
    11281 tctgagaaag gtcttagacc actttcccag tttgcctcac agctaatggt gtaaaacaaa
    11341 tagaccaccc tgtaacaggt ggtcatggtt agatatcagc tcatttaaga gacaaaggcg
    11401 ttgatttcag attcaatatt ggcaattttt tcttcggcaa gcgcaagggt gtcaccaaca
    11461 gttgcgatat aaaatttaat ttttggctct gttcctgatg gtcttacagc aaaccatgaa
    11521 tcatcagcta gggtatattt taagacattg cttggaggag tggttagctg ggtttgacca
    11581 gctttatgag ttgccgtctg actgaggaaa tcctctgtta acacaatatc agtgtgatta
    11641 aactgcgcag gggcatgctt gcggaattta tccataatct gtttgatttc agctgcgcca
    11701 tcaacaccag acagtgtaac agaaatggtt ttttctgcaa agtagccgta ttctttgtaa
    11761 atgtcatcaa taccatcagc aagggttagt ccacgagagc ggtagtaggc agcaatctca
    11821 gccaccaata gcaccgcttg aatagcgtcc ttatcacgta caaatggttt aatgagataa
    11881 ccaaagctct cctcaaagcc aaacatatag gtgtaattgt gcttttcttc aaattcttga
    11941 attttttcag caatgaactt gaagcctgtt aagacattaa acatggttgc cccgtagctc
    12001 tctgcaattt tagtcactaa ttcagtagag acaatggatt tggcaagagc ggcattgtta
    12061 ggtagggttc cagcctgctg atgtgcttct aaaatatact tagcaattaa agcaccaatt
    12121 tggttgcctg ataggttgcg atagctgcca tctgcctgcc gaatttcaac cccaagacgg
    12181 tcagcatctg gatcagtagc aacaagaaca tcagcatcaa cctgacgtcc aagctcctca
    12241 gcaagagtaa atgcctcttg actttcagga ttaggagatt tgacggtaga aaaatctgga
    12301 tctggcttag cctgcacctc aaccacctga acggacttaa agcctgcttg tgccaaggca
    12361 cgacgtgcta gcatttcacc tgttccatga agaggtgtat agacaatttt catgtcacga
    12421 ccatagtcat tgatgaggtc ttggttgata ttgacctttt tgacctcttc taaataagca
    12481 aggtcaacag cttcaccaat aacctcgatg agcccattag ctttggcttt ctctaaatca
    12541 gcaagcctaa tggcaaaggg gttatcaatc gcacgaatgt aatctgttag agcgtcggcg
    12601 tcagctggag gcatttgacc gccgtcagac ccataaacct tatagccgtt gaatggtgca
    12661 gggttgtgac tggcagtaac catgataccg gcaaaagcac ccaaatgtcg cacagcaaag
    12721 gaaagctcag gtgttggccg aaggctttca aaaacgtatg atttaatgcc atgagctgct
    12781 agtacctgtg cagattcaaa ggcaaattct ggagaaaaat gacgagaatc ataggcgata
    12841 gcgacaccgg ccttcttagc agcttctccc tttgactcaa ctaatgctgc caagccctca
    12901 gttgcttggc gaacaacaaa aatattgata cgattcgttc cagcgccaat atagccacgc
    12961 ataccagctg ttccaaattc aagattggtg tagaaggcat cttcctttgt tttttcgtcc
    13021 atgctaagta attcatctct taaataggct ggtagatctg gaatatcaag ccatttttga
    13081 tagttttctg tgtaagtcat agtattctcc tttatatttt taaccgcttt
//
LOCUS       DARYXW010000056        13084 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.056, whole genome shotgun sequence.
ACCESSION   DARYXW010000056 DARYXW010000000
VERSION     DARYXW010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13084)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13084)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13084
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.056"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(262..1941)
                     /locus_tag="TV191_001319"
     CDS             complement(262..1941)
                     /locus_tag="TV191_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507826.1"
                     /translation="MTKKVASLVLIGLDSLILAGFYWIYLPPMNVMSLEFWFFVILAL
                     ILAMVSLFILSLFGLKKTVTSFFTQKSGRKDVTSGLSLKQLTGGIKWLGLALAVIIAG
                     LSLLLAVNTRMFRAKSYAHVIKVKDADFNKDFPDTDLSALALLDRDSAEKIGDTYLGT
                     IDKVSQFGISDEYRQITIGKLPYRVSPLEYKSFWKWLTNRKDGIGYYVKVNQTTGKAE
                     LVKLNQPMKYSHSEFMFRDTMRHLRFQYPMTIFSDPSFEVDDDGNPYYVATTYAPKFG
                     LSSQEPTGVILLDAVSGKSQYYELKDVPKWVDRVYSADNVLERVNDYYTYQKGYWNTV
                     FSQTDVKQTTDSYNYITIGSDIYLYTGITSATADSSNLGFILVNMRTREVTNYKLPSA
                     TEASAMKSAEGEVQEKKYTATAPTLVKLNDKAYYLISLKDGAGLIKSYALVDAEDYQQ
                     VTVNNDIQTLISQFTDKDTSSLSVSDTNDQKVKMITGQVEQLASQIISGTTVYYISSK
                     GQIYKIKASSETSDRLPFLKVGDQFKAQLADDNYLNHMTIESSSADQAITE"
     gene            complement(2116..7020)
                     /locus_tag="TV191_001320"
     CDS             complement(2116..7020)
                     /locus_tag="TV191_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEL1507827.1"
                     /translation="MEKKERFSLRKYKSGMVSVLIGILFLTGMGSVVAEEQGVSSAHV
                     SAGQHQESREVLSVSQASEGAAVNAQDIDSQSSKAEEKTEEAMATGLVSSEMEALTES
                     NQSVKQQEESRELPPVNMDTHRWIKTEGAWNRGYKGQGKVIAVIDTGIDASHHAMRIT
                     NPAAAKFTSKADIDQRKKAAGIQYGVWLSDKVVFAHNYVENNDKVKEIKDDPFEGLDD
                     LDFDVIVQQIDIRRNRPQSIEAPQETVIKLDDTSGGTIIDWQDTDDDSKYESHGMHVT
                     GIAAGNGLKAAAAGERFLGIAPEAQVMFMRVFTHDLMGTGDPLFIKAIEDAVALGADV
                     INLSLGSANGSQLNGNRALMAAIEKARQAGVSVVVAAGNERAFGSDHADPLVTNPDYG
                     LVGAPSAGRTPTSVASINNKVIIERLMTVEGLKDRADLNHGKAIYLESVDFKDIKTSL
                     GFDVPYSFVYVKALTKEGYQEREVSGKIVLVQRDPNRKYDDIIAEAKQYGAAGVLIFN
                     NEPGKANRTMRLSSKGMVLPSAFISHEFGMAMAALNGNGTGTLTFDAEVSKAISQKGN
                     EMNYFSNWGLTSDGYLKPDITAPGGDIYSTFNDDHYGSQSGTSMATPHIAGASLLVKQ
                     YLEALQPQLAKDKLADLVKNILMSNAQIHINPKTNTTTSPRQQGAGLLNIETAVTSGL
                     YLTGKDNYGSISLGNVTDQISFEVTIHNLSNQAKSLRYQTELLTDQVDTKEGRFALRS
                     RSLKTYQGEQVDVPAQGHKTITITLDASNFTEELSKQMPNGYYLEGFVRFVDSKDEHK
                     DNINIPFVGFKGAFENLPVVEASIYELKAQGKTGFYFDSSGLKDEIYVGNHFTGLVTV
                     GTDTNVSMTTIADNGLHTLGTFRNKDGKFVLERNAVGYPVLAISPNGDNNQDFAAFKG
                     VFLRKYQGLQARVYKGTDTDRKELLWTSPSALQGDKNFNSDIRFAKSTTLLETGFSGK
                     SLTGADLPDGKYHYVVSYYPDVVGAKRQEMVFEVIVDRQTPELGTASYNPVTHRFRPS
                     QWLDRGQAGVLRDSVFYLETKDDKPYTITINDGLKYVTVSDNKQFVERLADGSFVLPV
                     DQVALGDFYYMVEDFAGNVAIAKLGNHLPEKIGQAELALTLTDINAQHQLSYSDNLNM
                     TAADTGLVTNEAELLIISRNRPQSRLAKLGQTAVISPNDDGNKDFVAFKGLPHQVYQD
                     LKVTVFAQEDTAMTSPIWSSQPGASVANVDSTAWYGTRASGARVMSGHYRYVVSYLDA
                     NGMPQAEAYAVTVSHQKPVITPASFQADGATEVFRPGPSKGQSPIGIVREEVFYLVKK
                     DGRKFDLTVEDQLIRFKDNKVMIAQNADGTYTIPKVEGVAEADYYYLVEDEAGQIAYM
                     SLAALRAVGPDKGVVSVALALDVLENKKEPAFTYLIRDEQGKPIEQLDYFNSSANSLI
                     LPFGRYTVELLAYDNHLFELRSDNLVSFSLDADTRLASVAFEMTRPIVASVWLLFNQV
                     LPEGSRVSLKAANGQLISLAPSLYVPSAYGKTLRQGSYEVLVELPEGYQLIGQGGLEV
                     SHNGVIELTFEVIKAKQPQLEHQAGGLTHYTGSSITSSALTAQAVKKAQVLPSTGEQA
                     AVNLVLLGLLSLGAAGSCQRQKKY"
     gene            7373..8200
                     /locus_tag="TV191_001321"
     CDS             7373..8200
                     /locus_tag="TV191_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEL1507828.1"
                     /translation="MKLISWNIDSLNAALTGESPRALLSRAVLDTLVAQDADIIAIQE
                     TKLSAKGPTKKHLESLLGYFPNHLNVWRSSVEPARKGYAGTMFLYKKELNPIVTFPDI
                     GAPTTMDAEGRIITLEFNDFFVTQVYTPNAGDGLRRLEERQLWDQKYADYLAQLDAQK
                     PVLATGDYNVAHKEIDLANPASNHRSPGFTDEERLGFTNLLNRGFTDTFRFIHGDIPN
                     VYSWWAQRSKTSKLNNTGWRIDYWLTSNRLIDKVSRSEMISSGERQDHTPILLEIDL"
     gene            complement(8276..8629)
                     /locus_tag="TV191_001322"
     CDS             complement(8276..8629)
                     /locus_tag="TV191_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEL1507829.1"
                     /translation="MITIYQYPKCSTCQKALAELKTLVSEVDIIDIKANPPKAEQLKQ
                     WLEHSDYSLKSFFNTSGMRYRELGLKDKVNSLSVEEAAELLATDGMLIKRPILLQDNQ
                     VLQVGYRTAYKDLGL"
     gene            complement(8633..9145)
                     /locus_tag="TV191_001323"
     CDS             complement(8633..9145)
                     /locus_tag="TV191_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEL1507830.1"
                     /translation="MWGGQILPLYECVYQSPLGKISLVATDVALIGAWFEGQRYFQAG
                     IKVQPIWQEQHALLKRACLWLDAYFERKPYPMLDCLSPQGTDFQRAVWRELQTIRWGE
                     TLSYGELAKRLQCRSAQAVGGAIGRNPLSIFIPCHRVLAADGRLIGYAGGLEKKAWLL
                     RHEQISVNKE"
     gene            complement(9602..10156)
                     /locus_tag="TV191_001324"
     CDS             complement(9602..10156)
                     /locus_tag="TV191_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1507831.1"
                     /translation="MEIRLAFPNELSQIMTVINSAKSALAQSGSSQWQKADGYPAYQD
                     IAADVLQGQGYVALLEGQIVAYAAVIDGQEDAYDKIYDGRWQHNHHRYVTFHRVAVLS
                     DRTGQGIAQTFLQGLIEGQHGPDFRIDTHEHNQVMRHIIEKLGFVYCGKVPIDGERLA
                     YQKIKKSHERAAYQEISEDSRYSY"
     gene            10367..10996
                     /locus_tag="TV191_001325"
     CDS             10367..10996
                     /locus_tag="TV191_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEL1507832.1"
                     /translation="MIKEFCAENLTMLNQLTSQSVNRVELCDNLAVGGTTPSYGVIKE
                     ACDLLHDKQISVATMIRPRGGDFVYNDLELRAMEADILKAIEAGTDALVIGLLTKDNQ
                     LDTDAIEQLLPATQGLPLVFHMAFDLIARDQQIASLEQLIDYGFVRILLHGSSDTRSI
                     YENIDHIKQLVKAAQHRIEIMIGGGVTADNCQELSQLTGTAIVHGTKII"
     gene            11455..12540
                     /locus_tag="TV191_001326"
     CDS             11455..12540
                     /locus_tag="TV191_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507833.1"
                     /translation="MTTRYFYKLLLTMLTLALGGFSLSACHSKISKPYQVAIFDKDHV
                     RTFMEKADSLVPVETISRTQHKLFERESFKQAKQGYFAKTREGNDLKVLLTHIDQASL
                     EEKVLHADGNDAYTSTTDGDYFYTTAVFADRIDCYKYDRHLKKQAHKSILNQDTINAS
                     NQFLVIDDALYLLVSAVDIKSQQPKTELWKMDKSFTITDRIDLDESTAYLRMVNVGRT
                     LYITQAADGILETGEPRPGNKVMTYDLDSGQKSYLMLHVNSPRAIYHHAKTNELIIEN
                     DQHYNPDFAWTIYQLDTGEERTIRFEELAGQETSSPYFMMTSSNYYFLFPKRLYRYDC
                     SNHQMTCINLDQYGVTHAHALIAKPTP"
     gene            12726..>13084
                     /locus_tag="TV191_001327"
     CDS             12726..>13084
                     /locus_tag="TV191_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TQXA domain-containing protein"
                     /protein_id="HEL1507834.1"
                     /translation="MYESPEKIPYQLPLYDKYEGNNSLFRDNASPNFRADVKDITATL
                     VAVLSNGYPTGKSSFCKDYCPDEIRARQLTQLAIWYFTDGISEETLKSNYSLNDLEFQ
                     GLKYLIQAGKTAGTSNNR"
BASE COUNT         3701 a         3210 c         2606 g         3567 t
ORIGIN      
        1 atcaaaacta tcctgcaatc agctgtttag ccattttaaa aggcaaacaa aaaccatgcc
       61 acattgcaat gacatggttt tcttcaagaa aggagcgagc tttggtttgg tactttctac
      121 aactgatctc caatagcagc tgctcctcgt tagtccctga gccacaggtg actgagcttt
      181 cctgcggcta ctctgatagt accagctact cttacaactg cataaagcag tggctgccag
      241 ccaagctaaa gctaaacaat attactctgt tatagcttgg tctgctgacg agctctcaat
      301 ggtcatgtga ttgaggtagt tgtcatcagc cagctgagcc ttaaactggt ctccgacctt
      361 taggaaaggc agacggtcac tagtttcact gcttgccttg attttataaa tctgaccctt
      421 ggaggaaatg taataaaccg ttgttcctga gataatctgg ctggccaatt gctccacctg
      481 cccagtaatc atcttgacct tctgatcatt ggtgtctgac actgacagcg agcttgtgtc
      541 cttatctgtg aattgtgaga ttaaggtctg aatgtcatta ttcactgtta cctgctgata
      601 atcctctgca tcaaccaagg cataggattt tatcagacca gccccgtcct tcaatgagat
      661 aaggtaataa gccttgtcat ttaacttgac tagggttggt gcagttgcag tgtatttctt
      721 ctcttgaact tcgccctcgg ctgatttcat ggcagaggcc tctgttgcag aaggcagctt
      781 atagttagtg acctctctgg tacgcatgtt aaccaaaata aagccgagat ttgacgaatc
      841 agctgttgct gaggtgattc ctgtatagag gtaaatgtct gagccgatgg taatgtagtt
      901 atagctgtct gttgtttgct tgacatctgt ctggctaaag acagtgttcc aatagccctt
      961 ttgataggtg taatagtcat taaccctctc caaaacattg tcagcagaat agacacgatc
     1021 aacccatttt ggaacgtcct ttagctcata gtattgagac ttgccgctaa ccgcgtctaa
     1081 caggatcaca cccgtcggct cctgagagga caggccaaat tttggggcgt aggttgttgc
     1141 gacatagtaa gggttaccat cgtcatcaac ctcaaatgac gggtctgaaa aaatggtcat
     1201 cgggtactgg aagcgcaaat gcctcatggt gtctctaaac ataaattccg aatgagaata
     1261 cttcataggc tgatttaact tgactagctc tgccttacca gttgtctgat tgaccttgac
     1321 ataatagcca atgccgtcct tacgattggt tagccatttc cagaaggatt tgtactccaa
     1381 gggagaaaca cgataaggga gcttgccgat cgtaatctga cggtactcat cagaaatacc
     1441 aaactgcgat accttatcaa tggtcccaag ataagtatct ccaatctttt cagccgaatc
     1501 tcgatccagc aatgccaagg ctgacagatc agtgtctgga aaatccttgt taaaatcagc
     1561 gtcctttacc ttaatcacat gagcatagga cttagcacga aacattctag tattaacagc
     1621 taacagcaag gacaagccag caatgataac agcaagggca agaccaagcc actttatgcc
     1681 accggttaat tgcttgagtg aaagacctga ggtcacgtcc ttgcggccag acttttgcgt
     1741 gaaaaagctg gtcactgttt ttttcaaccc aaacaaggac aggataaaaa gactcaccat
     1801 cgccaagata agcgcaagaa tcacgaaaaa ccaaaattct aagctcatca cgttcattgg
     1861 cggcaaataa atccagtaaa agccagccag gatcaagctg tctaagccaa tcagcaccaa
     1921 agaagcaact ttttttgtca tactaatctc ctcgtcacac cctaaggcta tcaggggtat
     1981 tcaatatctt ctcaccgcta ttgtaccaca tttcccctca aaagatgaca tctcagccag
     2041 acatttttat cagctcttag agcacctcag ctagaatgat caatacagct gacaggctac
     2101 gctcatagag cttgcttagt acttcttttg acgctggcaa gagcctgctg ctccaagact
     2161 gagcaagcct agcaggacta gattgaccgc tgcttgctca cccgttgatg gtaggacttg
     2221 ggctttttta actgcttgtg ctgttagggc agagctagtg attgatgagc cggtataatg
     2281 agtcaagcct ccagcctgat gttctagctg aggctgctta gctttgataa cctcaaaggt
     2341 aagctcaatc acgccattat gtgatacctc tagacctcct tgaccgatta gctgatagcc
     2401 ctccggtagc tcaacgagga cctcatagct tccttgtcgc agtgttttac cataggcact
     2461 tggaacatag agagacggag ctagagaaat caactgacca tttgctgctt tcaggctgac
     2521 cctgctgcct tctggcaaga cttggttaaa caagagccaa acagaagcca caataggcct
     2581 tgtcatctca aaggcaactg aagcaagcct tgtatccgca tctagactaa agctaaccaa
     2641 gttgtcagac cttagctcaa acagatgatt atcataagcc aagagctcaa cggtgtagcg
     2701 tccaaatggc aatatcaagc tattagctga gctattgaaa tagtccaact gctcgattgg
     2761 cttgccctgc tcatcacgaa taagataagt aaaggctggc tcttttttgt tctcaagcac
     2821 atcaagtgcc aaggcaacgg acactactcc cttgtctggt cctacagctc gcaaagcagc
     2881 taagctcata taagcaatct gacctgcctc gtcttccact agataataat aatctgcttc
     2941 tgcaacgcct tcaaccttag gaatggtgta ggtgccgtct gcattttgag caatcatcac
     3001 cttattatcc ttgaatctga tcagctgatc ttcgacagtt agatcaaact tgcgtccatc
     3061 tttcttgaca aggtagaaga cctcttctct aacaatacct attggacttt gtcccttgct
     3121 tggtcccgga cgaaagacct cagtagcacc atcagcttgg aagctagctg gcgtaatgac
     3181 tggcttttga tggctaactg tcaccgcata ggcctctgct tgaggcatac cattagcgtc
     3241 tagataagaa acaacatagc gataatgtcc tgacatcacc ctagctcctg aggctcttgt
     3301 gccataccaa gcggtgctgt caacattagc cacgcttgca cctggttggc tagaccagat
     3361 tgggcttgtc atagctgtat cctcctgggc aaagaccgtt acctttagat cttgatatac
     3421 ttgatgtggc aagcccttga atgccacaaa atccttgttt ccatcatcat tcggcgagat
     3481 gacagcagtt tgacctaatt tagccaaacg actctgtggt ctattgcggc taataatgag
     3541 aagctctgct tcatttgtca ccagtcctgt atctgcagca gtcatgttga ggttatcact
     3601 gtagctcagc tgatgctgag cattaatatc agttagggtc aatgccagct cagcctgacc
     3661 gattttttct ggcaagtgat ttcccagctt agcaatggca acattgcctg caaaatcctc
     3721 gaccatgtaa taaaaatcac caagcgccac ctgatcaact ggcaggacaa aagagccatc
     3781 tgctaagcgc tcaacaaact gcttattgtc tgatacggtc acatacttta agccatcatt
     3841 aatggtaatc gtataaggct tgtcatcctt tgtttccaag taaaaaacac tatctcgaag
     3901 aacaccagcc tgaccgcgat caagccactg agacggtctg aagcgatggg tcacagggtt
     3961 atagcttgct gttcctagct ccggcgtttg acgatccaca atcacctcaa agaccatttc
     4021 ttgacgtttc gctcctacca catctggata ataagaaacc acataatggt atttgccatc
     4081 tggtaggtca gctccggtca gcgatttacc actaaagcct gtttctaaca gcgttgttga
     4141 cttggcaaag cgaatatcac tgttaaagtt tttatcccct tgaagggctg atgggctcgt
     4201 ccagagcaac tccttacggt ctgtatctgt tcccttatag accctggctt gcaggccttg
     4261 gtatttacgt aagaacaccc ctttgaaggc agcaaagtct tgattgttgt cgccatttgg
     4321 agagatagcc aacacaggat agccaactgc atttcgctcc aacacaaatt taccgtcttt
     4381 attacgaaag gttcctagtg tgtgcaagcc attgtcagca atagtagtca tagagacatt
     4441 ggtatctgta ccaacagtca ccagcccagt aaaatgattg ccgacataaa tctcgtcctt
     4501 tagccctgag ctgtcaaaat aaaagccagt ttttccttga gcctttagct cataaataga
     4561 ggcttcaaca acaggtaggt tttcaaaggc tcccttaaag ccaacaaatg gaatgttgat
     4621 gttatccttg tgctcgtcct tgctatccac aaagcgaaca aagccctcta gataatagcc
     4681 atttggcatt tgcttagaga gttcctctgt aaagtttgag gcatctaggg taatggtaat
     4741 ggtcttgtgt ccttgagcag gtacgtcaac ctgttctccc tgataggttt tcagagatct
     4801 tgaacgtaag gcaaaacgtc cttccttagt atccacctga tcagtcaaca attctgtctg
     4861 gtagcgcagc gacttagcct gattagacaa gttatggatt gtcacctcaa agcttatctg
     4921 atcagtcaca tttccaagag aaatactgcc atagttgtct ttacctgtca ggtacagacc
     4981 actggttacc gcggtctcta tattcaagag ccctgctccc tgctggcgtg gcgatgtggt
     5041 ggtattggtc ttagggttga tgtggatctg agcattactc atcagtatat ttttgaccag
     5101 atctgctagc ttatccttgg caagctgtgg ttgaagcgct tctagatatt gcttgaccaa
     5161 aaggcttgcc cctgcaatgt gtggggttgc catactagtt cctgactggc tgccatagtg
     5221 atcatcgttg aaggtcgagt aaatatctcc acctggagca gtgatgtcag gcttcaaata
     5281 gccatctgag gtcaagcccc agttagagaa atagttcatc tcatttccct tttggctaat
     5341 ggccttagag acctcagcat caaaggtcag agtgcctgtt ccattgccat ttaaagcagc
     5401 cattgccatg ccaaattcat gagagataaa ggcagatggc agcaccatcc cctttgaact
     5461 cagacgcatg gtgcggttag ccttgcctgg ctcattgtta aaaatcaaga ccccagctgc
     5521 cccgtactgc ttggcctctg ctataatatc gtcgtatttc cgattaggat cacgctgcac
     5581 caagacaatc ttgccactca cttcgcgttc ttggtagcct tcttttgtca aagctttgac
     5641 ataaacaaat gagtatggta catcaaagcc aagactagtc ttaatgtcct tgaaatcaac
     5701 agattccaaa tagatagcct ttccatgatt taagtcagcc ctatctttca agccctccac
     5761 cgtcatcaga cgctctataa tcactttgtt attaatagac gcaactgagg taggagtccg
     5821 gcctgctgat ggagccccca ctaagccata atcaggattt gtcaccaacg ggtctgcatg
     5881 atctgaccca aaggcacgct cattacctgc agcaacgacc acagagacac cagcctgcct
     5941 tgccttttcg atagctgcca tcagggcacg attcccattc aattgagacc cattggccga
     6001 gcccagactt aaattaatca catcagcgcc caatgccaca gcatcttcga tggctttaat
     6061 aaataagggg tccccagttc ccatcaaatc atgggtaaaa acccgcataa acatgacctg
     6121 agcctcagga gcaatgccta aaaagcgttc gccagctgct gccgccttga gcccatttcc
     6181 agctgcaatg cctgtcacat gcatgccatg cgattcatat ttgctgtcat catctgtatc
     6241 ttgccagtca atgatagttc ctcctgatgt gtcatcaagc ttgatgaccg tttcctgagg
     6301 tgcctctatt gactgcggac ggttcctcct aatatcaatc tgctgcacaa tcacatcaaa
     6361 atccaagtcg tcaaggccct caaacggatc gtcctttatc tcctttacct tatcattgtt
     6421 ttccacatag ttgtgggcaa agactacctt atcgcttagc cagacaccgt actgaatgcc
     6481 tgctgctttt ttgcgctggt caatatctgc ctttgatgta aacttagcag ctgctggatt
     6541 tgtaatgcgc atggcatggt gactagcgtc aataccagta tcaataacag caataacctt
     6601 accttgaccc ttatagcctc tattccaagc tccttctgtt tttatccagc ggtgagtatc
     6661 catatttact ggaggtagct cgcgcgattc ttcttgctgc ttgactgatt ggttagattc
     6721 cgttagcgct tccatttcgg aagaaactaa tccagtcgcc attgcctcct ctgtcttttc
     6781 ctctgcttta cttgactggc tgtcgatgtc ctgagcatta acagcagctc cctcactagc
     6841 ctgagagaca gacaatacct cccttgattc ttgatgttgt cctgctgaca cgtgagctga
     6901 gctaactccc tgctcctcag ccacaactga tcccatccct gtcagaaaaa ggattccgat
     6961 caacacagaa accattcctg atttatattt cctcagtgag aagcgttctt ttttctccac
     7021 ttgatgtcct cctagattta ttaaaaaagg ttattttaaa caaatgattc atttatgttt
     7081 taatcaataa tgtctaagct atttaaccat tttttaatca caaaagcaat aagactagaa
     7141 gctctcagtt tatgtcattt tttaatcatt caactcactg aaatgaggcc tctcagaacc
     7201 tgtctcatca acagataagg ctaaactcag ccgctagact tcaaaaatgt cacaccattt
     7261 ttagacatta cctgtcctca tacctataac agaaccaagc ttccacagtc gccttggcct
     7321 tatttttttg ttacaatata ggttaagatt atcatttaga aagcgaagaa aaatgaaact
     7381 catctcatgg aacattgatt ctttaaatgc tgcgctcact ggtgaatctc ctagagccct
     7441 cttatcacgc gctgtacttg atactctcgt ggcacaggac gctgatatta ttgcaattca
     7501 agagacaaag ctatctgcca aaggccctac caaaaagcac cttgagagct tgcttggcta
     7561 ctttcctaat catctcaatg tttggcgttc atctgttgag cccgccagaa aaggctatgc
     7621 cggaaccatg ttcctctata aaaaagagct caatcccatt gtcacattcc cagatatcgg
     7681 agctcctacc actatggacg ctgaagggcg tatcatcacc ctagaattta acgatttctt
     7741 tgtcacacag gtctacaccc caaatgccgg tgatgggctt agacgcttgg aagagcgcca
     7801 gctctgggac caaaaatatg ccgactacct agcccagctc gatgcccaaa agcctgtttt
     7861 ggctactggt gattacaacg ttgcccacaa ggaaatcgac ctggctaacc cagctagcaa
     7921 ccaccgctct ccgggcttta cagatgagga gcggcttggc tttacgaacc tgcttaaccg
     7981 agggtttaca gatacctttc gctttattca tggcgatatt ccaaacgttt atagctggtg
     8041 ggcacagcgc agcaagacca gtaaattgaa caataccggc tggagaattg attactggct
     8101 cacgtcaaat cggttgattg ataaggttag tcgctcagag atgatttcct caggagaacg
     8161 tcaggatcac acaccgattt tattagaaat tgatctatag actagaagca ttcggacaaa
     8221 tcaacccaga cattaaaaaa aaatggctct gcaagagaac cgttttttta atcgcttaaa
     8281 gacctagatc cttataggct gttcgatacc ctacctgcaa gacctgatta tcctgtaaga
     8341 ggatcggccg cttaatcagc atgccatctg ttgccaaaag ctccgctgcc tcctcaacgc
     8401 tcagtgaatt aaccttatct ttaagcccaa gctcacgata acgcatacca ctggtattga
     8461 aaaagctttt gaggctataa tctgaatgct ctagccattg tttcagctgc tcagctttag
     8521 ggggattggc cttaatatca atgatatcaa cctcagaaac cagggtcttt agctcagcaa
     8581 gggctttttg acaggtacta cactttgggt attggtaaat ggtaatcatt agctactcct
     8641 tattaacact aatttgctcg tgcctgagca accaggcctt cttttcaagt cctccagcat
     8701 agccaatcaa gcgaccatca gcagccagta cacgatgaca gggaataaaa atacttaaag
     8761 gattacgtcc tatggcacca ccaacagcct gagccgaacg acactgcagg cgcttggcaa
     8821 gctcaccata gctcaaggtc tctccccatc ttatcgtctg caattctcgc cagacagctc
     8881 gctgaaaatc agtaccctgt ggagataagc aatcaagcat gggatagggc ttcctctcaa
     8941 agtaagcgtc aagccacaaa caggctcttt ttaacagggc atgctgctcc tgccagatgg
     9001 gctgcacttt aatcccagcc tgaaaatacc tttgaccttc aaaccaggct cctatcaaag
     9061 caacatcagt cgcaaccaag gatatttttc ctaagggcga ttgatacaca cactcgtaca
     9121 atggcaagat ctgacctccc cacataatag cttattccct tgactattta ttataagaaa
     9181 aagcctagct aaaggcaaga aggagccctc tgacaccaca acaaacgcat gaaaaaacaa
     9241 tagcggctct ttcaatgctg ccatacaatc gttagtgtca aaagtcgctt actatacagc
     9301 tgcccccctt gaaaaacgaa gctggaaaga cacaacatgc taaagctgtt tcacgcgctg
     9361 gtgcctgatt agatgttctt ctaattaaag gccaatgttc tgattaaaaa gtcatttcat
     9421 gcgctgatac ctactcaaat aaaaacacat agcgtggggc tagaccaatc cctcacaagt
     9481 catcaatagt tcgtctatga gctacacttt atcacattgg gataggcaga catatttgcc
     9541 ggctcagttg tacttgcctg atagctaacc aaaagcccga taagcttttt ccgatcctat
     9601 atcaatagct gtagcggcta tcctcgctaa tctcctgata agcggctctt tcatggcttt
     9661 tcttaatttt ttgataggct aagcgctcgc catcaattgg taccttgcca cagtaaacaa
     9721 agcctaactt ttcaatgata tgccgcatga cctgattatg ctcatgagta tctatccgaa
     9781 aatctggtcc atgctgcccc tcaatgagcc cttgcaaaaa ggtctgagca attccctgac
     9841 cagtcctatc actcagcacc gccacacgat gaaaggtcac ataacggtgg tgattatgct
     9901 gccacctgcc atcataaatc ttgtcgtagg cgtcctcttg gccatcaata acagccgcat
     9961 aagcaacaat ctgcccctca agcaaagcca catagccctg cccttgcaac acatcagcag
    10021 caatatcctg ataagcagga tacccatctg ctttctgcca ttggctggag cctgattggg
    10081 ctaaggcaga cttagctgaa ttgatcactg tcatgatctg actaagctca ttaggaaaag
    10141 caagtctaat ctccatcgtt cacactcaca atctattctg atttgatgat gctatgctac
    10201 cgcaaaaagc cttacacctt gtcactctgc tagggacacc tcatagcggt atgcctgctt
    10261 ctcatctcag ctgagtatag cacaatagtc atcatttgac aaaaagcctc ttcaaggatt
    10321 gccagcaatc atgctataat aaagtaaatc acaaaggaga accattatga ttaaagaatt
    10381 ttgtgctgaa aacctaacca tgctaaacca attgaccagc cagtcggtca atcgtgttga
    10441 gctctgcgac aatcttgcag tcggtggcac cacaccctct tatggtgtca tcaaggaagc
    10501 ctgcgacctc ctacatgaca agcagattag tgtcgcaaca atgatccgcc caagaggagg
    10561 tgattttgtc tataacgacc ttgaattgcg tgctatggaa gcagatatct taaaggctat
    10621 cgaagcagga actgatgcct tggtcatagg cttactcact aaggacaacc agcttgacac
    10681 cgatgctatc gaacagctcc taccagctac acaaggactc cctctggttt ttcacatggc
    10741 ctttgacctg attgctcgcg accaacaaat cgcaagccta gagcagctca ttgactatgg
    10801 ctttgtacga atcctgcttc atggctcaag cgataccaga tccatctatg aaaacattga
    10861 ccatatcaag cagttagtca aggctgctca gcaccgaatc gaaatcatga ttggtggagg
    10921 tgtcacagct gataactgcc aagagctaag tcaactaaca ggaacagcta ttgtgcatgg
    10981 cacaaaaatc atctaactat cagctcaaat aaaggaaaag tcactcccta caaggaggta
    11041 aataatagca gcccttctcg ttgaaggcca tacctgagcc cttagactag gctcctagca
    11101 aactaatagt ataggacctt cgctgccttt acatcaaaaa ggctgccgtc cagaaaaaga
    11161 gaaagccaca cattgataga aaaccatagc tggctctact actatcagta tctatcatca
    11221 gcttctgagc tgcctaaaag tttcggtgat cattaacaag tacagactat ttgtttctaa
    11281 attagatcat aaaacagaca attataggaa gcgacaagtg aatcattatt cattttttat
    11341 tgattactat gatactataa gtaaggatag cgctttcttt ttgtctttgc tttgcctgac
    11401 tattaggctc tagatttatt ttttaccata ctaatataag aatcggaata aataatgaca
    11461 acaaggtatt tttataagct attgctaacg atgttgacac tagcattagg aggattttcc
    11521 ctatctgctt gccactccaa gattagtaag ccctatcaag tcgctatttt tgacaaggat
    11581 catgttagga cctttatgga aaaagctgac agtctggtgc ctgttgagac catctctcga
    11641 acacagcaca agctatttga gcgagaaagc tttaagcagg ccaagcaagg gtattttgca
    11701 aagacaagag aaggaaatga cctcaaggtt ctgttaactc acattgatca agcaagccta
    11761 gaagaaaaag tccttcatgc tgatggcaat gacgcctaca cctctacaac tgatggtgat
    11821 tacttttaca caacagctgt ctttgccgat cgtattgact gctacaagta tgaccgccac
    11881 ttgaaaaaac aggctcacaa gtctattcta aatcaagaca ccattaatgc cagcaatcag
    11941 tttctggtga ttgatgacgc tctgtacctg cttgtcagcg ctgtagacat caagagtcag
    12001 cagcccaaaa ctgagctatg gaaaatggac aaatccttta ctatcactga tcggatagat
    12061 ctggacgaaa gcactgccta tctgcgcatg gtcaacgtcg gacgaaccct ttacattacc
    12121 caggctgctg atggcatttt agaaactgga gaacctagac ctggtaacaa ggtgatgacc
    12181 tatgacttag atagcggtca aaagtcctat ctcatgcttc atgtcaatag tcctagagcc
    12241 atttaccacc atgccaaaac caatgagctt atcatcgaaa atgatcagca ttataatcct
    12301 gactttgcat ggaccatcta ccagctagat accggagagg agagaaccat tcgctttgag
    12361 gagctagccg gtcaggagac aagctctccc tactttatga tgacctcaag caactactac
    12421 ttcctctttc caaaaaggct ttaccgatac gattgtagta accatcagat gacctgcatc
    12481 aacctagatc agtacggagt gacgcacgcc catgccttga tcgctaagcc cacaccataa
    12541 atcacaacag gcctaatcac cactcattca tctacacccc aatgcttaga caaagcagtg
    12601 tactgacccc caaaagttgg acacgacata ttagtgaaag gacttagccc tgtgcaatac
    12661 agaactaaat cctttcacta atatgtcgtg tccaactttt gggggtcagt acactttggg
    12721 aaagtatgta tgaatctcca gaaaaaatac cttatcaact acctctatat gacaagtatg
    12781 agggaaataa tagtttattt agagataatg cctcaccaaa ttttagggcg gatgtcaaag
    12841 atattacagc tactttagtg gctgttttaa gtaatggtta tccaaccggg aaaagcagtt
    12901 tttgtaaaga ctactgtccc gatgaaatca gggcaagaca attaacccaa ttagctattt
    12961 ggtattttac agatggtatt tctgaagaaa cgttgaaatc aaattatagt ctaaatgatc
    13021 ttgaatttca aggattaaag tatttaatac aggctggcaa aactgctggg actagtaaca
    13081 atcg
//
LOCUS       DARYXW010000057        12986 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.057, whole genome shotgun sequence.
ACCESSION   DARYXW010000057 DARYXW010000000
VERSION     DARYXW010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12986)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12986)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12986
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.057"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(24..1073)
                     /gene="citC"
                     /locus_tag="TV191_001328"
     CDS             complement(24..1073)
                     /gene="citC"
                     /locus_tag="TV191_001328"
                     /EC_number="6.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[citrate (pro-3S)-lyase] ligase"
                     /protein_id="HEL1507835.1"
                     /translation="MTQHLIQHIFPFDKQQKAKIDRLLQRQHIRRDPHLDYTCAIIDE
                     QGEPIATGSLYGNSLRCLAVDQAYQGEGLLNHIVSHLIEEAYSRGHHHLFIYTKIAAA
                     PLLLSLGFHVIAMVDDTLCFLENKKRGFEHYLSQLEKPQISPQKTAAIVLNANPFTLG
                     HLHLIEKACADNELVHLFMVSQDSSLIPYHIRKELIIKGTAHLANIIYHDSGPYMISQ
                     ATFPAYFQKDELAVIDSQAKLDIVIFRHIAEKLQIKSRYVGEEPTSMVTQHYNTVMLK
                     QLPCYSIDVQVIPRKTFAEGKIISASLARQAIKDDDYALLELLLPKTSLDFFRSEAAQ
                     PTITKIKAATDLKHY"
     gene            1340..2403
                     /locus_tag="TV191_001329"
                     /pseudo
     CDS             1340..2403
                     /locus_tag="TV191_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004347311.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
     gene            complement(2489..3373)
                     /gene="citG"
                     /locus_tag="TV191_001330"
     CDS             complement(2489..3373)
                     /gene="citG"
                     /locus_tag="TV191_001330"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase CitG"
                     /protein_id="HEL1507836.1"
                     /translation="MTKKVFDDISRLALKALLYEVSLSPKPGLVDQLDNGAHDDMSFL
                     TFVDSALALAPFFKIYLDIGFYHAKEDPGLIFERLRASGIEAEQAMFSATKGVNTHKG
                     VNFSLALLLGATGMYLADQPQLLDHVTAFTEEDSLAICQLVKPLTAHLLETDFGSLDL
                     KKELTYGEKLFLDYGIKGPRGEASEGYPTIAHKALPFLRKSLRSTDQETAQLQLLVYL
                     MSIVEDGNLIHRGGIKAWRQVKQDMLLLHNSSLSTADLKAALSAYNDKLIQKHLSPGG
                     TADLLVLSLYFAFLENQL"
     gene            complement(3366..4061)
                     /locus_tag="TV191_001331"
     CDS             complement(3366..4061)
                     /locus_tag="TV191_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1507837.1"
                     /translation="MNPIIEAVKNNLDLSRNIPLKIAFYNALKKTIILRQIPAGSRIN
                     EKEFSIALNISRTPIRYALGLLSEEHLVEHIPKKGIIVKGVSIQDACEIFEIRKALET
                     LATSTAMYLMTEEDFQVMHDLLADCETFIEDDDLNRILDNFNSFNNLIYSYSQMVRLK
                     EIVTELQTYLVYFRKISISSLERRKRALSEHWMIYRGMKNRDHEQITLITHEHLNSSL
                     EFILQEMSRRQDD"
     gene            complement(4214..5617)
                     /locus_tag="TV191_001332"
     CDS             complement(4214..5617)
                     /locus_tag="TV191_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CitMHS family transporter"
                     /protein_id="HEL1507838.1"
                     /translation="MLLTVLAYAMIIIFMYVVMKKKMTPFTALVMIPLIMTIAVILTG
                     SADFTSDAKFVAFVGEDGLAKNLTAIGPMIMYGINNTAKTGIMLLFAILFFSIMLDAG
                     LFDPITEKMIRFAKGDPMKVLMATAIVAAAVSLNGDGTTTTLICCSAFLPIYKKLNMR
                     IMNLGVLIILQNTIMNLLPWGGPTARAMSVLSVGPEILGYLAPGMVLSLLYVICWVAP
                     SMGRKERARLGVVDLTEEEMRKLTDITDPDTLSIRRPKNFAFNAILTIGLITWLVAGS
                     FYKAIAMAPLLLFAVGTCIALIVNYPVLKDQTKRIGDNAGDAVQVVILVFAAGIFMGL
                     FQGSGMASALAQSFATIIPKQLAGFWGLVIALISAPGTFFISNDGFYYGILPVLAEAG
                     AEYGFSNMAMALASLMGQAFHLLSPLVAFIYLLLRLTGLDMGEWQKEAAKYAIIIFII
                     FVVTIIAMGQMPLYIPQ"
     gene            5999..6343
                     /locus_tag="TV191_001333"
     CDS             5999..6343
                     /locus_tag="TV191_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507839.1"
                     /translation="MQFFQNMFRRSKKEAATSHQDRENKPEFPLDDWEPVPSYIAADK
                     KDYQTVSLIASAIAAGEQASSQFKVKRILQRNPEALTVSLIASSIAAGVYPESQFLVR
                     SIYSKKVNVSHK"
     gene            6361..6756
                     /locus_tag="TV191_001334"
     CDS             6361..6756
                     /locus_tag="TV191_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010777321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="HEL1507840.1"
                     /translation="MLRKFKITIDGKEYLVEMEEIGAPSQAPVVPPVQPAVAPAPVAE
                     KKAAEAPQAPAAPVSAGADAMPSPMPGIILKVLVNVGDVVHENQPLLILEAMKMENEI
                     VASTAGTVTGIHVTAGQVVNPGEGLITIS"
     gene            6806..7927
                     /locus_tag="TV191_001335"
     CDS             6806..7927
                     /locus_tag="TV191_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium ion-translocating decarboxylase subunit
                     beta"
                     /protein_id="HEL1507841.1"
                     /translation="METLIAGVTSITIPQIIMMLIGAVLMYLGIKKEYEPTLLVPMGL
                     GTILVNFPGTGVLTQVVNGVEQEGVFDALFNFGIGTELFPLLIFIGIGAMIDFGPLLQ
                     NPFMLLFGAAAQFGIFFVVVVAVLAGFDIKEAASIGIIGAADGPTSIFVANQLAKDLL
                     GPITVAAYSYMALVPIIQPFAIKLVTTKKERRIRMTYKAENVSQLTKILFPIVITLVA
                     GFIAPISLPLVGFLMFGNLLRECGVLDRLSQTAQNELVNIISILLGLTISIKMQAELF
                     LNVQTLLIIIFGLLAFIMDSIGGVMFAKFLNLFRKEKINPMIGAAGISAFPMSSRVIQ
                     KMATDEDPQNFILMYAVGANVSGQIASVIAGGLLLAYFS"
     gene            8109..8417
                     /gene="citD"
                     /locus_tag="TV191_001336"
     CDS             8109..8417
                     /gene="citD"
                     /locus_tag="TV191_001336"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase acyl carrier protein"
                     /protein_id="HEL1507842.1"
                     /translation="MEIKQIAVAGSLESSDMMITISPNDGQGIVLELDSSVEKQFGNH
                     IRALIKTTLARLGVESATIEAVDKGALDCTIQARTIAAVHRAAGVEHYNWKEIDSWNA
                     "
     gene            8405..9292
                     /gene="citE"
                     /locus_tag="TV191_001337"
     CDS             8405..9292
                     /gene="citE"
                     /locus_tag="TV191_001337"
                     /EC_number="4.1.3.34"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (pro-3S)-lyase subunit beta"
                     /protein_id="HEL1507843.1"
                     /translation="MERLRRTMMFVPGANAAMLRDAPLFGADSIMFDLEDSVSLKEKD
                     TSRALVHFALKTFDYSNVETVVRVNSLDSCGALDIEAVVLAGVDVIRLPKTETAQDII
                     DVEAVIERVERDNGIAVGRTRMMAAIESAEGVLKAREIAKASNRLIGIALGAEDYVTN
                     MKTRRYPDGQELFFARSMILHAARAAGIAAIDTVYSDVNNTEGFQAEVRHIKQLGFDG
                     KSVINPRQIPLVNEIYTPTEKEISHAKQVIWAIREAESKGSGVISLNGKMVDKPIVER
                     AQRVIALATAAGVLTEEDI"
     gene            9294..10826
                     /gene="citF"
                     /locus_tag="TV191_001338"
     CDS             9294..10826
                     /gene="citF"
                     /locus_tag="TV191_001338"
                     /EC_number="2.8.3.10"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase subunit alpha"
                     /protein_id="HEL1507844.1"
                     /translation="MVKNKLGRDIPQEYADHYGVFEGELARITSYNESSRRIKPVKPG
                     DSKLLGSIREAIEKTGLKDGMTISFHHHFREGDFVMNMVLDEIASMGIKDLAIAPSSI
                     ANVHEPLIEHIKNGVVTSITSSGLRDKVGAAISSGIMEKPVVIRSHGGRARAIASGDI
                     HIDVAFLGAPSSDEYGNVNGTIGKATCGSLGYAMIDAKYADQVVVLTDHLVDYPNTPI
                     SIPQTDVDYVVTVDAIGDPQGIAKGATRFTKNPKELLIAEYAAKVITQSPYFKNGFSF
                     QTGTGGASLAVTRFMREAMLQENIKASFALGGITNAMVELLEEGLVEKILDVQDFDYP
                     SAVSLGKNAQHYEIDANMYASPLSKGSVINQLDTCILSALEVDTNFNVNVMTGSDGVI
                     RGASGGHCDTAFAAKMSLVISPLIRGRIPTFVDEVNTVITPGTSVDVVVTEIGIAINP
                     NRPDLIEHFKDLKVPQFSIEELKEKAYSIVGTPDRIQYGDKVVALIEYRDGSLIDVVY
                     NV"
     gene            10819..11379
                     /gene="citX"
                     /locus_tag="TV191_001339"
     CDS             10819..11379
                     /gene="citX"
                     /locus_tag="TV191_001339"
                     /EC_number="2.7.7.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase holo-[acyl-carrier protein]
                     synthase"
                     /protein_id="HEL1507845.1"
                     /translation="MSKELIFKGKAVTLADMLRAREDRSLRQGKLLTEFSNESLLSVT
                     MNIPGPIKTSPALLEVFDSVIKAILEKLSGNQISYQLRLLPKTGYEYYLVTALDSQAL
                     KLKMIELETDLPIGRLMDLDVLVLTNQLPTPISRTALGFPPRSCYLCSKEAKACSRNR
                     SHSVADMQTALVHLLQSFFDGGNQLS"
     gene            11410..12801
                     /locus_tag="TV191_001340"
     CDS             11410..12801
                     /locus_tag="TV191_001340"
                     /EC_number="4.1.1.112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxaloacetate decarboxylase subunit alpha"
                     /protein_id="HEL1507846.1"
                     /translation="MTKIRITETVLRDGQQSQIATRMTTKEMIPILETLDNAGYHALE
                     MWGGATFDSCLRFLNEDPWERLRTIRKVVKKTKLQMLLRGQNLLGYRNYADDVVRSFI
                     QKSIENGIDIVRIFDALNDPRNLETAVSATKEFGGHAQVAISYTTSPVHTIDYFVALA
                     KAYQAIGADSICIKDMAGVLTPETGYQLVKRIKESIALPLEVHTHATSGISEMTYLKV
                     VEAGADIIDTAISSFAGGTSQPATESMVIALEDLGIDTGVDMTRLTKIAEYFNTIRDH
                     YRAEGILNPKVKDTEPKTLLYQVPGGMLSNLLSQLKEQGLSDKYEEVLAEVPKVRADL
                     GYPPLVTPLSQMVGTQALMNVISGERYKVVPNEIKDYVRGLYGQPPAPLGEGIKEKII
                     GDEAVITCRPADLIEPQLPLLRQEIAGYACCEEDVLSYASFPQQAKDFLGRREDPFYD
                     IPVQYVTVDIAMD"
BASE COUNT         3802 a         2590 c         2875 g         3719 t
ORIGIN      
        1 gttagagagg gggtagttgt tggttaataa tgcttaaggt ctgttgctgc tttgatctta
       61 gttatcgtgg gctgagcagc ctcgctccta aaaaagtcaa gtgaggtctt aggaaggagt
      121 agctctaaga gagcataatc atcgtccttg atggcctgtc tggcaagaga ggcgctgatg
      181 attttgcctt ctgcaaaggt ttttctaggg ataacctgca catcaatgct atagcaaggc
      241 agctgcttga gcatgacagt gttgtaatgc tgtgtgacca tgctagtagg ctcttcgcca
      301 acataacgac tcttgatttg gagtttttct gcaatgtgac ggaaaatgac aatatccaat
      361 ttagcttgac tatcaataac tgctagctca tctttttgaa aataagcagg aaaggttgcc
      421 tgactaatca tgtaaggtcc actatcgtgg tatatgatat ttgctaggtg tgcagttcct
      481 ttgatgatta attcctttcg gatatggtag gggatcaggc tactgtcttg actgaccata
      541 aagagatgaa cgagctcgtt gtcagcgcag gccttttcaa tcagatgcag atgaccaagg
      601 gtaaatggat tagcatttaa aacgattgct gcggtctttt gaggactgat ctggggcttt
      661 tctagctgtg acaggtagtg ctcaaagccc ctttttttat tttctaaaaa acaaagagta
      721 tcatcaacca ttgcaatgac atgaaagcca agacttagca atagaggggc agctgctatt
      781 ttagtgtaga taaacagatg atgatgccca cgtgagtagg cctcctcaat cagatgtgag
      841 acaatgtgat taagtaagcc ttctccttgg taggcttgat caacagctaa gcagcgcagg
      901 ctattgccgt acaaagagcc agtagcaata ggctcgcctt gctcgtcaat aatagcacag
      961 gtataatcta aatgagggtc tcttctaatg tgctgtcttt gtaacaaacg atcaattttt
     1021 gctttttgct gcttgtcaaa gggaaaaata tgctgtatca agtgctgcgt catatgctca
     1081 cctcttatta cgaaattatc ctcttgcctt tattatagca cgctataggg cttattctta
     1141 agcatcttag ctggtttatg aaaagaatgc acaaaaaaga catcaatgac ctattgtctc
     1201 tgatgtcatt atgatatgat taggactttt agataaatga ttaaggtatg gaggatttaa
     1261 gcctgcaaaa ggtggcaata ataattctga cttatgctat aatagagcta ttgatattaa
     1321 gggggataaa ggggctggta tgctttcgat tctaatgact ttatttgttg ggacgctggg
     1381 agggcttgtt gctaagcggc tgagtattcc tgcccctttt atgattggca gtatggtagc
     1441 tgttgcccta gcttctatcc tgacaaagca ggtagaggct attaacccca tgaagatttt
     1501 tgctcagatt attagtggtg cctatattgg ccaaagcgtc agcaaatctg acctgcttaa
     1561 tctgcccaag ctagccaagt ctattattag tctcatgtcc ttgttcacgc tgaatatgtt
     1621 tcttcttggt ggggtatttg tttactgctt tgatcttgat cctgtaacag ccttgttgag
     1681 ctgtttacct ggtggcatta tggacgtttc tcttatggca gttgatatgg gagcaaaggc
     1741 tgatatagtt gcgacattac agtcggctcg actggtcggt atgctcttgt ttcttcctgt
     1801 ttgggtgacg ttttgggtca atcgctttga cccaaaagca aaagctacta aaaaaaaaag
     1861 atagtcaaaa gcgctagctc ccaagataca agaccttcta ggaaagagca gctatggaat
     1921 aatgtccagg ttttaagcat tgctaccatt ggaggtttga tcggtttagg gctaaagata
     1981 cctgtaggcg ctctgattgt ttctttgctt ttttcaacag cactgaaggt gcttcggcaa
     2041 acaagtcaaa tgccaagtac acttcgttat atagcgcagg tttttgctgg ctctattatt
     2101 ggaacaagct ttactcagga tagtttgctt caaatgggac gtctgattgt tcctattctt
     2161 ttacttttga gtagctatct gatcatcaat ctcttttttg gctatatcat gtataaaaaa
     2221 ggtatcttgg atttgcaatc ggcactcttt gcctcatcgc ctgctggtgc gacagacatt
     2281 tcactattgg ctggtgagct tggcggagat atgcctaaaa tcgctggtat tcaaatcagt
     2341 cgaaccctct atactgttgt catcatgccc ttgttggtta aatggctcat tagtatatgg
     2401 taaacagaaa agcccctcag agcataaacc agagatacct agtcattacc aaataacata
     2461 tcaaggatct tgttcaggct tggagctgct ataattgatt ttctaaaaaa gcaaagtaga
     2521 ggcttagcac tagcagatca gcagtccctc caggactgag atgcttttgg atcagcttgt
     2581 cgttgtaggc tgacaaggca gcctttaagt cagcagtgct caaagagctg ttgtgcaata
     2641 gcagcatgtc ctgtttgact tgccgccaag ctttgatgcc tcctcggtga atcaggttgc
     2701 catcttccac aatagacatg aggtaaacca gcagttgcag ttgagcggtc tcctgatcag
     2761 tgctgcgaag gctcttgcgc aaaaaaggca gcgccttgtg agcaattgta ggatagccct
     2821 cgctggcttc tcctctaggg ccctttatac cgtaatctag aaagagcttc tcaccatagg
     2881 tgagctcttt ttttaggtct aagctaccaa aatcagtctc aaggagatga gctgttagag
     2941 gcttgacaag ctgacaaata gccagactat cctcctcagt aaaggctgtt acatggtcca
     3001 agagctgtgg ttgatcggca agatacattc ccgttgcccc aagcagaagt gctaaggaaa
     3061 aattgactcc cttatgggta ttgactccct tagttgcgct gaacatggct tgctcagcct
     3121 caatgcctga ggcacgcaag cgctcaaaga tcagaccagg atcttcctta gcatggtaaa
     3181 aaccaatgtc taaataaatc ttaaaaaagg gggctaaggc cagagcgcta tcaacaaagg
     3241 ttaagaagct catgtcatca tgagccccgt tatcaagctg atccacaagc ccaggcttag
     3301 gagataagga cacttcgtaa agtaaagcct ttagagcaag cctgctaata tcatcaaata
     3361 ccttcttagt catcctgacg cctgctcatt tcctgtagga taaattctag tgagctgttg
     3421 aggtgctcat gcgtaataag ggtgatttgc tcgtggtcac gatttttcat gccacgataa
     3481 atcatccaat gctcagataa agcgcgtttt cgtctttcta gggaagagat cgaaattttt
     3541 ctaaagtaaa caaggtaggt ctgcaattca gtgacaattt cttttaatct gaccatctga
     3601 ctatagctgt aaatcagatt attaaagctg ttgaaattat ctagaattct gttgagatcg
     3661 tcatcttcta taaaggtttc acaatcagcc aacaaatcat gcatgacctg aaaatcttcc
     3721 tctgtcatca aatacatagc ggtgcttgtt gccagtgttt caagcgcttt tctgatttca
     3781 aagatttcac aagcatcttg aatactaaca cccttgacaa taatgccttt tttaggaata
     3841 tgctctacca aatgctcctc tgataacaat cctagagcgt acctgattgg tgttctgcta
     3901 atatttaggg caatggaaaa ttctttttcg ttgatacgac tgccagcagg aatttgtctt
     3961 aaaataatag ttttctttag ggcgttataa aaagctattt tcaaagggat attgcgggat
     4021 aggtcaagat tattctttac tgcttcgata ataggattca tataatctcc ttaatgttca
     4081 tatcatgata ttattatact gaaaatcatt actaatgaaa ataataatta gcctcctaaa
     4141 aggcgaaagc catgctcgtg aaagaacatg gctttcatta gcccacacta cagtcctaat
     4201 aatagctcgt gacctattgt ggaatgtaaa gcggcatttg tcccattgca ataatggtta
     4261 caacaaagat aataaagata ataatcgcgt atttagcagc ttctttttgc cattctccca
     4321 tatcaagccc agtaagacga agaagcaggt aaataaaggc caccaatgga ctgagcaaat
     4381 ggaaggcttg tcccatcaga gaagcaagag ccatcgccat gttgctaaag ccatattcag
     4441 ctccagcctc cgctaagact ggcaaaatac catagtagaa gccatcattt gagataaaga
     4501 aagtaccagg agctgaaatc agggcaataa caagtcccca gaagccagcc aattgctttg
     4561 gaataatcgt tgcaaagctt tgagcaagag cactagccat accagagcct tggaaaagtc
     4621 ccatgaagat accagcagca aaaaccagaa taacaacctg aacagcatca ccggcattat
     4681 caccaatacg ctttgtttgg tcctttagga caggatagtt aacaataagg gcaatacagg
     4741 ttcccactgc aaataaaaga agtggtgcca tagcaatagc cttatagaaa gagccagcaa
     4801 ccagccaagt gattaagccg atggttaaga tagcattaaa ggcaaagttt ttaggacgac
     4861 ggatagaaag cgtatctgga tctgtaatgt ctgttagctt acgcatttcc tcttcggtca
     4921 aatcaacaac accaagtctt gcacgctcct tgcgtcccat gcttggcgca acccaacaaa
     4981 tgacataaag aagagacaaa accataccag gtgcaaggta tccaaggatt tcaggtccca
     5041 cactaagcac agacatggca cgcgcagttg gaccacccca aggaagcagg ttcatgatag
     5101 tgttttgcag gataatcaag acaccaagat tcatgatgcg catgtttaat ttcttataga
     5161 ttggtaaaaa agcagagcag caaatcaagg ttgttgttgt accatcacca ttaagtgaaa
     5221 cagctgctgc aacaattgca gttgccatca agaccttcat cgggtctccc ttagcaaagc
     5281 gaatcatttt ttcagtaatc gggtcaaaca agccagcatc tagcataatg gaaaagaaca
     5341 ggatcgcaaa aagcagcata atacctgtct tagcagtgtt attaataccg tacatgatca
     5401 taggaccaat agctgtcaga tttttagcaa gcccatcctc accaacaaag gcaacaaatt
     5461 tggcgtctga tgtaaaatca gcagagcctg ttaatataac agcaattgtc attatcaacg
     5521 gaatcatgac cagagctgta aaaggggtca tttttttctt catgacgaca tacatgaaga
     5581 taataatcat agcataagct agaactgtta ataacatatt gttatctcct ttttgatttt
     5641 atgacttcag tataaatgaa agcgttcgca aaagaaatac ctccatgtac ggaaaaacac
     5701 aaaaaaaaca ttttgaaagc agatcctgaa aaaataaatg gttacattaa tgtttttcaa
     5761 cagcagttag ttgctcttat cttcagtaat cgcagtgtgt ttcagcattt tttaaaatca
     5821 gtcatattta ttttagttaa ctgtttttat aaaaatggtt aactaaaata agaaaatcct
     5881 tgaaaatgtg aaagcgctct tagaaagaac acaaaaaagc cattccaaaa ggatgaggtg
     5941 gtatataata agcatagaag cttcccattt gtgggcaaac taagaaagga ggtagcttat
     6001 gcagtttttt caaaacatgt ttagacgctc taaaaaagag gcagccacaa gccatcaaga
     6061 cagagaaaat aagcctgaat ttccgttaga tgactgggag ccagtgccta gctacattgc
     6121 tgcagataaa aaggattatc agacagttag tctgattgcc agtgccattg cagctggcga
     6181 gcaagctagc agtcagttta aggtaaaacg aatcctacag cgcaatcctg aggccttaac
     6241 cgtatcctta atagcatcaa gcattgcagc tggtgtttat ccagagagtc aatttctggt
     6301 taggtccatt tatagtaaga aagtaaacgt tagccacaaa tagtaaaagg agaaaagatt
     6361 atgttgcgta agtttaaaat taccattgac ggaaaagagt acctagttga aatggaagaa
     6421 atcggtgctc cctcccaagc cccagtagta cctcctgttc aaccagcagt agctccagcc
     6481 cctgtagccg aaaaaaaggc agcagaagct ccgcaagctc cagcagcacc tgtatcagca
     6541 ggggcagatg caatgccctc acctatgcct ggtattatct taaaggtttt agttaatgtt
     6601 ggtgatgtcg tacatgaaaa tcagcctcta ttgattttag aggctatgaa aatggaaaat
     6661 gagattgtcg cctcaacagc tggtacagtc acagggattc atgttactgc aggtcaggtg
     6721 gtcaaccctg gtgaaggctt aatcaccatt agctaatcct aagtcgtgtc ttgatttaaa
     6781 atgttgtaga aaaggaagta catttgtgga aacattaatt gcaggagtaa cctccatcac
     6841 tattcctcaa atcattatga tgcttatcgg tgctgtctta atgtatctag gaataaaaaa
     6901 agaatacgaa ccaaccttac tagttcccat gggactgggt actattttag tcaactttcc
     6961 cggcacagga gtcttaacac aggttgttaa tggtgttgag caagaagggg tctttgatgc
     7021 cttattcaat tttggaatcg gtacagagct gtttccatta cttattttta tcggtattgg
     7081 tgccatgatt gactttggtc ctttacttca aaatcctttc atgctattat tcggtgcggc
     7141 agctcaattt gggattttct ttgttgtcgt tgtagccgta ttagctggct ttgatattaa
     7201 ggaagcagct tcaattggta tcattggtgc tgctgacggt ccaacatcaa tttttgtagc
     7261 aaaccaattg gcaaaggatt tgctagggcc tatcacagtg gcagcttatt cttacatggc
     7321 tttggttccg atcattcagc cctttgcgat caagctagtt actaccaaaa aagagcgtcg
     7381 tattcgtatg acctataagg ctgagaatgt gtcacaatta acgaagatcc tctttcctat
     7441 tgtgatcaca cttgtagccg gctttattgc tccaatttcg ttaccattgg ttggtttttt
     7501 gatgtttggg aacctgcttc gtgaatgtgg tgtcttggac cgattgtcac agaccgctca
     7561 aaacgaattg gtcaatatca tcagtatttt actaggacta accatctcta tcaaaatgca
     7621 ggccgagctt ttcttgaatg tgcaaaccct gcttattatc atttttggtc tgttggcctt
     7681 tatcatggat tcgattggtg gtgtgatgtt tgccaaattc ttgaatttat tccgtaagga
     7741 aaaaatcaac ccaatgatcg gagctgctgg aatttcagcc tttccaatgt caagtcgtgt
     7801 gattcaaaaa atggccactg atgaggatcc gcagaatttc atcttgatgt atgctgtggg
     7861 tgctaatgta tctggtcaaa tcgcctcagt tattgcaggt ggcttgctgc ttgcttactt
     7921 tagctaagaa aggacgtgct tatgacaatc aatatagacc atttgatcca atcctttgag
     7981 ctaatggcac ttggaatggc aggagtattt gttgtattag gaattctcta tattgtagca
     8041 gaggctctga ttaagctatt tccagtagaa aaataataga atatgatcta aacaaggagg
     8101 tcaatcaaat ggagatcaaa caaattgctg ttgctggttc gcttgaatct agcgacatga
     8161 tgataacaat atcacctaat gatggtcagg gaatcgtttt ggaattggat tcaagcgttg
     8221 aaaaacaatt tggcaatcat atcagagcat taatcaagac aacacttgcc aggctgggcg
     8281 ttgagtcagc aacgatcgaa gctgttgata agggagcctt ggattgtacc attcaggcaa
     8341 gaacaattgc agcagtccat cgtgctgctg gagttgagca ttacaactgg aaggagatcg
     8401 actcatggaa cgcttaagaa gaacgatgat gtttgttccg ggcgctaatg cggctatgct
     8461 aagagatgca cccttgtttg gagcggactc tatcatgttt gatttagagg attcagtttc
     8521 cttaaaagaa aaagacacct ctcgcgccct tgttcatttt gccctaaaaa cctttgatta
     8581 ttcaaatgtt gagacagttg tgcgcgttaa tagcctagac tcttgtggtg ctctggatat
     8641 tgaggcagtt gtgttagcag gtgttgatgt tattcgcttg ccaaagacag aaactgccca
     8701 ggatattatt gatgttgagg cagtcattga gcgtgttgag cgtgacaatg ggattgctgt
     8761 tggtcgtaca cgcatgatgg cagctatcga gtctgcagaa ggggtcttaa aagctcgtga
     8821 gattgcaaag gcctcaaatc gtctcattgg tattgccctc ggcgcagagg attatgtgac
     8881 taatatgaaa acacgtcgct acccagatgg acaagaatta ttctttgccc gcagcatgat
     8941 tcttcacgca gcacgtgctg ctgggattgc agcaattgat accgtttatt cagatgtcaa
     9001 caatacagaa ggcttccaag ctgaggtgcg tcatatcaag caattaggct ttgatggtaa
     9061 atctgtcatc aaccctcgtc agattccatt ggtaaatgag atttatacac caaccgaaaa
     9121 agagattagt cacgccaagc aagtgatctg ggccattcgt gaggctgaaa gtaagggatc
     9181 aggtgtcatt tcattaaatg gaaaaatggt agataagcca atcgtagagc gtgcacagcg
     9241 tgttatcgct ttggcaacag ctgctggggt attaacagag gaggacattt agcatggtta
     9301 aaaataaact tggtcgtgat attcctcagg agtatgctga tcactatgga gtatttgaag
     9361 gagagctagc acgtatcact agctacaatg aatcaagccg ccgcattaag cctgtaaagc
     9421 caggtgacag taaattgctt ggctctattc gtgaagctat tgaaaagaca ggcctaaaag
     9481 atggcatgac catttcattt caccatcatt ttcgtgaggg ggacttcgtc atgaatatgg
     9541 ttcttgatga gatagccagc atgggaatca aagatttagc tattgctcca agctctattg
     9601 ccaatgtgca tgagccatta attgagcaca ttaaaaacgg agtggttaca agcattacct
     9661 catcaggttt acgtgataag gttggggcag ctatttcatc agggattatg gaaaagcctg
     9721 ttgtgattcg ttctcatgga ggacgtgctc gtgcgattgc tagtggtgat attcatattg
     9781 acgttgcctt tttaggagca ccaagctcag atgaatatgg taatgtcaac ggtacgattg
     9841 gtaaggctac ctgcggctca cttggctatg ctatgatcga tgccaagtac gcagatcagg
     9901 tggtggtgct gacagatcac ctagttgatt atcctaacac cccaattagc attccgcaaa
     9961 ctgatgttga ttatgtcgtg acagttgatg ctattggtga tccacaagga atcgctaagg
    10021 gagcaacgcg gttcaccaaa aatcctaagg agctcctaat tgccgaatat gccgctaagg
    10081 ttatcacaca gtcgccttac tttaaaaatg gcttttcctt ccaaacaggt acaggaggag
    10141 cttccttagc agtgactagg ttcatgcgtg aggccatgct tcaagaaaat atcaaggcaa
    10201 gctttgccct tggaggcatt acaaacgcta tggtagaatt gctcgaagaa ggattagttg
    10261 agaaaatcct agatgtacag gattttgatt acccttcagc agtttcgctt ggtaaaaatg
    10321 ctcagcatta cgaaattgat gctaacatgt atgcctcacc actaagcaag ggatcggtta
    10381 tcaatcaatt agacacctgt attttatcag cgcttgaggt tgacactaat ttcaatgtta
    10441 atgtcatgac aggttctgac ggtgttattc gtggggcttc cggagggcat tgtgacacag
    10501 cctttgctgc caaaatgagt ctggtgattt caccccttat ccgcggacgc attccaacct
    10561 ttgtagatga ggtaaataca gtaattacac ctggaacaag cgttgatgtg gttgtcacag
    10621 aaataggtat tgctatcaat ccaaaccgtc cagatttgat agagcatttc aaggacttga
    10681 aggttcctca atttagtatc gaagaattaa aagaaaaggc ttactcgatt gttggaacac
    10741 ctgatcgtat ccaatacggt gataaggttg tagctcttat tgagtatcgt gatggcagcc
    10801 tgattgacgt tgtctacaat gtctaaggaa ttgattttca aggggaaagc tgttacccta
    10861 gctgatatgc taagggcacg cgaggacaga agccttcgtc aaggaaagct tttaacagaa
    10921 ttctcaaacg aaagcctgct ttctgtgacc atgaatattc caggccccat taaaacgtca
    10981 cctgctttac ttgaggtatt tgatagtgtt atcaaggcaa tcctagaaaa gctgtctggc
    11041 aatcagatca gctatcagct tcgtttgctg ccaaaaacgg gttatgaata ttaccttgtg
    11101 acagccttag atagtcaggc attaaagctc aaaatgattg agcttgagac tgatttaccg
    11161 attggcaggc taatggattt ggacgtttta gtgctgacaa atcagctgcc aacccctatc
    11221 agtcgaacag ccttaggctt tcctcctcgc agctgctatc tttgctcaaa agaggctaag
    11281 gcttgtagta gaaatcgcag tcactcggta gcagacatgc agacagccct tgtacactta
    11341 ctccaatcat tttttgacgg aggcaatcag ctcagttaga ctcaacggta ttcttataag
    11401 gagaatgata tgacaaaaat ccgtataaca gaaacagttt tgcgtgatgg tcagcaaagt
    11461 caaattgcta cccgcatgac tacaaaggaa atgattccga ttttagaaac actagataat
    11521 gctggctatc atgccctaga aatgtgggga ggagctacct ttgattcttg cctacgtttc
    11581 ttaaatgaag acccttggga gcgtctaaga accattcgta aagtagtcaa gaaaactaaa
    11641 ttacaaatgc tcctgcgtgg gcaaaatctt ttgggctatc gtaattatgc tgacgatgtc
    11701 gtccgcagct ttatccaaaa atcaattgaa aacggtattg atattgtgcg catttttgat
    11761 gccctaaatg atccacgtaa tctagagaca gctgtttcag caacaaaaga attcggtggc
    11821 catgcacagg ttgctatttc ttacacaaca agtccagttc atactatcga ttattttgta
    11881 gccttagcaa aagcctatca ggctattggt gcagattcga tttgtatcaa ggatatggct
    11941 ggtgtgttaa ccccggagac cggttatcaa ttagtgaagc gtatcaagga aagcattgct
    12001 ctaccacttg aggttcacac gcatgctacc agtggtattt ctgaaatgac ctatctcaag
    12061 gtcgtagagg ctggtgcaga tattattgat actgccatat cctcatttgc cggcgggaca
    12121 agccagccag caacagaatc gatggttatt gctttagagg acttggggat tgataccgga
    12181 gtagacatga caaggctgac aaaaattgcc gagtatttta atactatccg agatcactac
    12241 agggcagagg gcattttaaa tcccaaggtt aaagacactg agcctaagac cttgctttat
    12301 caggttcctg gcggcatgct gtccaatttg ctaagtcagc ttaaggaaca gggactctct
    12361 gacaaatatg aagaggttct ggctgaggtt ccaaaggtta gagctgattt aggctacccc
    12421 ccactggtga ctccgctatc gcaaatggtt ggcacacagg ccttaatgaa tgttatttca
    12481 ggtgaacgct acaaggttgt cccaaacgaa atcaaagact atgtcagagg actttatggc
    12541 caacctcctg cgccactagg tgaaggtatt aaagagaaaa tcattggtga tgaagctgtt
    12601 atcacttgtc gtccagcaga tttgattgag ccacaattgc ccttgcttcg tcaagaaatt
    12661 gcaggctatg cctgctgtga ggaggatgtg ctgagctatg cctctttccc tcagcaggca
    12721 aaggatttcc taggacgcag agaggatccc ttttatgata tcccagttca gtacgtcacc
    12781 gttgatatag caatggatta atcaaaagaa taaaaagcaa gataactaat aaaatcaatc
    12841 tcctaattat tagtcaaagc tacctaccaa taaactcctt aatcagaacc acccgtctaa
    12901 tgaggtgccc ccaaaaggtt agtccaaaac tttaggctcc atgtcaactg tagtgggtag
    12961 ttgacaagct aacatctgga gaggac
//
LOCUS       DARYXW010000058        12729 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.058, whole genome shotgun sequence.
ACCESSION   DARYXW010000058 DARYXW010000000
VERSION     DARYXW010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12729)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12729)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12729
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.058"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            <1..894
                     /locus_tag="TV191_001341"
     CDS             <1..894
                     /locus_tag="TV191_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1507847.1"
                     /translation="KSVVGETDYKKACHAIKAAGYATASDYAELLIQLIEENNLQKWD
                     KEALKTNKEVTMTTANEIVQYCVDLANSGMGVDKDGCFGTQCADLPCFIVKNWFGIDL
                     WGNAIDLLNSAAAQGLEVIYNAPGVNPKASDLFVMEVAGSPYGHTGAVIEDSDGYTIK
                     TVEQNIDGNWDSLQVGGPARFNTRDFTGVVGWIRLPVDHTNQTVDTAPQTSDTIVETS
                     KTGTFTLDAAEINVRRWPNLTSEVVDSYKQGQTVSFDSEGYANGYYWISYVGGSGKRN
                     YMAIGPTDKDGNIISLWGKLN"
     gene            1058..1240
                     /locus_tag="TV191_001342"
     CDS             1058..1240
                     /locus_tag="TV191_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEL1507848.1"
                     /translation="MLIYDEFKQAVDNGYITGDTVAIVRKNGQIFDYVLPHEEVRNGE
                     VVTDEKVEEVMRELDK"
     gene            1438..1827
                     /locus_tag="TV191_001343"
     CDS             1438..1827
                     /locus_tag="TV191_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEL1507849.1"
                     /translation="MFYLAVHDQFDKKSRLAEIAKSRAGVISIDHIDCYHGTQSYLSL
                     FGKNKAGNTIIVTIEEQSEQLLLSRPSNGISAKEAQEIAYHAGARTIEAVTFGIENHK
                     RIWEVAAQNGYYLIDFKTAKVIKKEVL"
     gene            1824..3035
                     /locus_tag="TV191_001344"
     CDS             1824..3035
                     /locus_tag="TV191_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEL1507850.1"
                     /translation="MTKLSRRVLAMEESVTLAAGARAKALKAQGRDILSLTLGEPDFI
                     TPQHIQEKAIEAITTGKASFYTVASGLPELKDAIADYMARSYGYIPTRQEIVVGTGAK
                     YVLYAFFMAVLNPGDQVLIPTPYWVSYADQIKMVDGVPVFVQGLEENQFKVTVEQLEA
                     ARTDQTKVVLINSPSNPTGMIYSRQELEAIGNWAVQHDILILADDIYGALVYNGNQFT
                     PISALSEAIRRQTITVNGVAKSYAMTGWRLGFAVGDTDIIAAMGKIIGQTTSNVTTAS
                     QYAAIEAFGGDQTSVEEMRQAFEERLNTIYPLLNQVPGFEAIKPQGAFYFFPNVKKAM
                     EMKGFTDVTAFTDAILEEVGLAVVSGAGFGAPENIRLSYATDLATLKEAIRRLNQFMT
                     TDSSHDNKENE"
     gene            3048..4394
                     /gene="asnS"
                     /locus_tag="TV191_001345"
     CDS             3048..4394
                     /gene="asnS"
                     /locus_tag="TV191_001345"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEL1507851.1"
                     /translation="MTKKYVSIIDVKDHVGQEVTVGAWVANKSGKGKIAFLQLRDGSA
                     FFQAVAFKPNLIQAFGEEAGAAKFDTIRHLSQETSVLVKGIVKEDARSKFGYELDITD
                     LEVIGDSKDYPITPKEHGTDFLMDHRHLWLRSRRQAAIMQIRNAIIYASYEFFDQNGF
                     IKFDSPILSGNAAENTTELFETDYFGNPAFLSQSGQLYLEAGMMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYPFLSHEESLDLQEAYVKAMIQGVLDRAPQALELLERDTE
                     LLKRYIAEPFKRVSYDDAISLLQEHSTDDDADYEPIQHGDDFGSPHETWISNYFGVPT
                     FVINYPASFKAFYMKPVPGNEERVLCADLLAPEGYGEIIGGSVREDNYDKLLAKIKAE
                     GLNPEDYDFYLDLRKYGSVPHAGFGLGLERMVTFVAGTKHIREAIPFPRMLHRLKP"
     gene            4696..5790
                     /locus_tag="TV191_001346"
     CDS             4696..5790
                     /locus_tag="TV191_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1507852.1"
                     /translation="MMNRKKHTKLIRHYSICSAVAVLAAVSLGTGQDVQASEPNPYPD
                     VRRFLDEKYDGDVDKLSKQLQGYFGSLREYIEFELKNGKQGPAGPQGPKGDKGDPGEP
                     GPQGPVGPAGPKGDRGLDGRRGPAGQQGEAGPVGPQGPQGEQGPKGDRGEQGPKGERG
                     EQGPKGERGEQGPKGDRGEQGPKGERGEQGPKGERGEQGPKGDRGEQGPKGERGEQGP
                     KGDRGEQGPKGERGEQGPKGDRGEQGPKGDRGEQGPKGDRGEQGPKGDRGEQGPKGER
                     GEQGPKGDRGEQGPKKEPEKDTKPSVPKAPDNMAAPKAPEKKNPKAPAPKSAPKASLP
                     STGDTSQSFVAAALGFIASAGLLVFKRKKN"
     gene            6316..7206
                     /gene="rapZ"
                     /locus_tag="TV191_001347"
     CDS             6316..7206
                     /gene="rapZ"
                     /locus_tag="TV191_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEL1507853.1"
                     /translation="MSDKQINLVIVTGMSGAGKTVAIQSFEDLGYFTVDNMPPALVPK
                     FLELLERTNETQKVALVVDMRSRRFFKEINSILDHIELNANLKLRILFLDATDSELVS
                     RYKETRRSHPLAADGRVLDGIRRERELLVPLKSMSQHVVNTTDLTPRQLRKVISDQFS
                     SESDQASFRIEVMSFGFKYGLPLDADLVFDVRFLPNPYYQVALREQTGLDQAVFDYVM
                     THQESEAFYNHLLGLIVPILPAYQKEGKSVLTIAIGCTGGQHRSVAFAHRLAQDLTAD
                     WPLHESHRDINRRKETVNRS"
     gene            7203..8180
                     /locus_tag="TV191_001348"
     CDS             7203..8180
                     /locus_tag="TV191_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEL1507854.1"
                     /translation="MRNPKITVIGGGTGIPVILKSLRKEAVDITAVVTVADDGGSSGK
                     LRNAMQLTPPGDLRNVLLAMSDMPKFYERVFQYRFNEADGALAGHPLGNLIIAGISEM
                     QGSTYNAIQILTKFFHITGKIFPSSEQPLTLHAVFKDGHEVSGESSIASYQGMIDHVY
                     VTNTYNDDLPKASRKVVEAILQSDMIVLGPGSLFTSILPNLVIPEIKEALRVTKAEVV
                     YICNIMTQYGETEQFSDADHVAVLNQHLGRDLIDTVLVNVEQVPKSYMNSNQFDEYLV
                     QVEHDFAGLCKTAKRIISSNFLRLENGGAFHDGHLVVEELMNLVRITKL"
     gene            8177..9088
                     /gene="whiA"
                     /locus_tag="TV191_001349"
     CDS             8177..9088
                     /gene="whiA"
                     /locus_tag="TV191_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEL1507855.1"
                     /translation="MSFTTTVKEELIHLSASDQTELSAIIKLAGSLGLANQSLNLSIT
                     TENAKIARYIYALIEDTYHIIPEIRYHQKTNLKKNRVYTVYLDKQVDKLLADLKLADS
                     FFGIETGIEQQVMSDDDAGRAYLKGAFLAAGTVRDPESGKYQLEIYSVYLDHAQDLAQ
                     LMHKFMLDAKVIERKNGAVTYLQKAEDIMDFLIIIGAMSCKEEFEAVKLLREARNDIN
                     RANNAETANIAKTITASMRTINNIIKIMDTIGLDSLPVELQQIAQMRVANPDYSLQQI
                     ADSLDFAITKSGVNHRLRKINKLAEDL"
     gene            9448..10845
                     /locus_tag="TV191_001350"
     CDS             9448..10845
                     /locus_tag="TV191_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C69 family dipeptidase"
                     /protein_id="HEL1507856.1"
                     /translation="MSCTTILVGKKATYDGSTIVARTEDSQNGEFTPKKMTVVRPKDQ
                     PRHYQSVLSSFSMELPDQPMAYTSVPDALGKDGIWGEAGVNTLNVAMSATETITSNAR
                     VLGADPLVSSGIGEEDMLTLVLPYIRSAREGVLRLGAILEAYGTYEANGVAFSDEHEI
                     WWLETIGGHHWIARRVPDDAYVTNPNQFGLDHFEFNNPEEYLCSKDLKDFIAKYHLDL
                     TYSNEHFNPRYAFGSQRDKDRHYNTPRAWIMQQYFNPEFLQDPRSFELPWCQRPDRKV
                     TIEDVKYVLSNHYQDTPYDPYGPEGTPTSRKSFRPIGINRTSQTAILHIRPNKPKEIA
                     AIQWMAYGSMPFNTIVPLFTQVKTIPDYFANTVENVSTDNFYWTNRLIAALADPHFKH
                     HEADLEDYLEKTMAKGHAMLHAVEAALVKGQPVDLEEANQGMSDDIQADTQALLNKIL
                     FDASNLMTNRFSLSD"
     gene            11085..12635
                     /locus_tag="TV191_001351"
     CDS             11085..12635
                     /locus_tag="TV191_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HEL1507857.1"
                     /translation="MKKKYLLMMSVLGVFFAGQISQAKQVLADSKVKIVTTFYPVYEF
                     TKGVVGGEGNVSMLMKAGTEPHDFEPSTKDIKKIQDADAFVYMDDNMETWVPDMKKSL
                     TSKKVTVIKGTGDMLLVAGSGHSHEHDHDDADKKHDHDHDEEGHSHAFDPHVWLSPYR
                     SITVVETIRDGLSKAYPDKADHFKSNAAAYIEKLKELDKEYSDAFSAAKQKSFVTQHA
                     AFGYMALDYGLNQISINGVTPDTEPSAKRIAELSKYVKKYDINYIYFEENASSKVAKT
                     LAKEAGVKSAVLSPLEGLTEKDMKAGKDYFTVMRENLKTLRLTTDVEGKEILPEEDTT
                     KTVYNGYFKDKQVKDRKLSDWSGNWQSVYPFLQDGTLDQVWDYKAKKSKGKMTAAEYK
                     DYYTTGYQTDVSHIKINGKKNTMTFVRNGENKTFTYKYVGKKILTYPKGNRGVRFMFE
                     AKEPDAGEFKYVQFSDHAIAPGKAEHFHLYWGGDSQEKLHKELEHWPTYYDADLSGRA
                     VAQEINAH"
BASE COUNT         3747 a         2595 c         3074 g         3313 t
ORIGIN      
        1 aaatcagttg tcggggagac tgactataaa aaggcttgtc atgcaataaa agcagccggt
       61 tatgccactg caagtgatta tgcggagctg cttatccagt tgattgagga aaacaacttg
      121 caaaaatggg ataaggaagc cttaaaaact aataaggagg taacgatgac aaccgcaaat
      181 gagattgtac aatactgtgt tgaccttgcc aactcaggta tgggagttga taaagatggc
      241 tgttttggga cgcagtgtgc ggacttgcca tgttttatcg tcaaaaactg gttcgggatt
      301 gacttatggg ggaatgcgat tgacctgtta aacagtgcag cagcgcaagg tctagaggtt
      361 atctataacg cacctggagt taatccaaaa gctagtgact tatttgtcat ggaggtagct
      421 ggcagtcctt atggacacac aggagctgtt attgaggaca gtgatggcta taccattaaa
      481 actgttgagc aaaacattga cggcaactgg gacagtttac aagtaggtgg ccctgctcgc
      541 tttaatactc gtgactttac tggcgttgtc ggctggatta ggttacctgt tgaccatact
      601 aaccagacag tagatacagc accgcaaacg tctgacacca tcgtggagac gtcaaaaacg
      661 ggtactttta cacttgacgc cgcagagatc aacgtccgcc gctggccgaa tttaaccagt
      721 gaggtagtag atagttataa gcaaggccaa accgttagct ttgatagtga gggttacgcc
      781 aatggctact actggattag ctatgtcgga ggctcaggta agcgtaatta tatggcaatt
      841 ggtcctactg acaaagacgg gaatattatc agtctttggg gtaaattaaa ttaggaggta
      901 aagatccgag ataagacaaa accgctctct taatcgaggg cggttttttg tgtttcacac
      961 acatgtattc acacattggc atatccgtta taacggactt gttaaaatta gtccattaaa
     1021 ctagactttt tacgaataat aaggtaggag gtaatttatg ctaatatacg acgagtttaa
     1081 gcaggcagtt gataacggat atatcacagg agacacagta gcgattgtgc gcaaaaacgg
     1141 acagattttt gattatgtgt tgccgcatga ggaagtaagg aacggggagg ttgtgacaga
     1201 cgaaaaagtg gaagaggtga tgagagaatt agacaaataa aaaagacctc gtccagaagt
     1261 cggggaattg tcggggacaa cgtttgtaaa tgtttctatt ccaacataaa acattttttg
     1321 atataatagg aaggatcata tgcaaaggag ctgaaattgg acaagcacaa aaggctcaaa
     1381 acagttttat atcaatgtgc cagcttggtc gtactgcttt gtcttggagt gatgagcatg
     1441 ttttatcttg ctgttcatga tcaatttgac aagaaatcaa ggttagccga gatagcaaaa
     1501 tcaagagctg gtgtcatctc aattgatcat attgattgct atcatggcac tcagagctac
     1561 ctcagtcttt ttggaaaaaa caaggcaggc aataccatca tcgtcacaat agaggagcaa
     1621 tcagagcagc tcttgcttag tcgccctagc aatggcatta gtgctaagga agcacaggaa
     1681 attgcctacc atgccggagc aaggactatt gaagcagtga catttgggat tgaaaaccac
     1741 aagaggattt gggaggtggc tgctcaaaac ggctactatc tgattgattt caaaaccgca
     1801 aaagtgatca aaaaggaggt tttatgacca agctatcaag gcgcgtgtta gcaatggaag
     1861 aaagcgtcac cctagcagca ggtgctagag caaaggcact aaaggctcag ggacgcgata
     1921 ttttaagcct aactctggga gagccagatt ttataacacc gcagcatatc caagaaaagg
     1981 ccattgaggc catcaccact ggtaaggcaa gcttttacac tgttgcttcg gggttgccag
     2041 agctcaagga cgccattgct gattacatgg cacgatccta tggttatatt cctaccagac
     2101 aggagattgt agtggggaca ggcgccaaat acgttttgta tgcctttttc atggctgttt
     2161 taaatcctgg tgatcaggtg ttgattccga ctccttattg ggtttcttat gctgatcaga
     2221 ttaaaatggt agacggggta ccggtctttg tacagggctt ggaggaaaat caatttaagg
     2281 tcacagtaga gcagctagag gctgccagaa ctgatcaaac aaaggttgtt ttgatcaatt
     2341 ctccgtccaa tccaactggc atgatttaca gccgacagga gcttgaagcc attggcaatt
     2401 gggctgttca gcatgatatt ctgatcctgg cagatgatat ctatggtgca ttggtctaca
     2461 atggcaatca atttactcca atatcagcct tatcagaggc tattcgtaga cagaccatta
     2521 ctgtaaatgg cgttgccaag agctatgcga tgacaggctg gcgtttgggc tttgcggtcg
     2581 gagacactga tattatcgct gctatgggta agattatcgg gcaaaccacc tctaatgtga
     2641 caacagcgtc ccaatatgca gcgattgagg cctttggcgg tgaccaaacg tcagttgagg
     2701 agatgagaca ggcctttgaa gagcgcctca ataccattta tcccctgctc aatcaagttc
     2761 ctggctttga ggctattaag ccccaaggag ccttttattt ctttcccaat gtcaaaaaag
     2821 ctatggagat gaagggcttt accgatgtga cagcctttac tgatgcgatc ctagaagagg
     2881 taggactggc tgttgtcagc ggagctggct ttggtgctcc agaaaatatc aggctaagct
     2941 atgccactga tttggcaacc ctaaaagaag ctatcagacg actcaatcag ttcatgacaa
     3001 ctgacagcag ccatgacaac aaagagaatg aatagaaaag agacattatg accaaaaaat
     3061 acgtttccat tatcgatgtt aaagaccatg taggacaaga agtgacagtt ggtgcttggg
     3121 tcgccaacaa gtcaggcaaa gggaaaatag cctttttgca attgcgtgat ggctcagcct
     3181 ttttccaggc agttgccttt aagccaaacc tgatccaagc ctttggtgag gaagcaggag
     3241 cagctaagtt tgacacgatt aggcatctca gccaagaaac ctctgtctta gtaaagggca
     3301 ttgtcaaaga ggacgctaga tcaaaatttg gctatgagct agacattacg gacctagagg
     3361 ttattgggga ttccaaggat tatccaatta ctccaaagga gcatgggaca gactttctca
     3421 tggatcaccg tcacctttgg ctgcgctctc gcaggcaggc agcaatcatg caaatccgta
     3481 atgccatcat ctatgcttcc tatgagtttt ttgatcaaaa tggctttatc aagtttgata
     3541 gcccgatttt atcaggcaat gctgctgaga acacaacaga gctatttgag acagattatt
     3601 ttggcaatcc agcctttctc agccaatcag gtcagctata ccttgaagct ggtatgatgg
     3661 cgcttggtcg cgtctttgac tttggtccgg tatttcgtgc cgaaaaatca aaaacgcgcc
     3721 gccatctgac agagttttgg atgatggacg cagaataccc cttcttatcc catgaggaat
     3781 ccttagacct acaggaagcc tatgttaagg cgatgattca gggtgtgctt gatcgtgctc
     3841 cacaggcatt ggagcttcta gagcgtgaca cagagctgct gaaaagatac attgcagagc
     3901 ccttcaagcg tgtctcctac gacgatgcga tcagcctgct tcaggagcac agcacagatg
     3961 acgatgccga ctatgagcca attcagcatg gcgatgactt tggctcaccg catgaaacct
     4021 ggatttccaa ttattttggg gtcccaacct ttgtcatcaa ctacccagct agctttaagg
     4081 ccttttacat gaagccggtt cccggcaatg aagagcgcgt gctatgtgcg gacctgctag
     4141 caccagaggg ctacggtgag attatcggag gctcggttcg tgaggataac tatgacaaat
     4201 tgttggcgaa aatcaaggct gaaggcctaa atcctgagga ttatgacttt taccttgacc
     4261 ttcgcaaata tggctcagtg ccgcatgctg gttttggact tggactagag cgcatggtga
     4321 cctttgttgc aggtaccaag cacattcgtg aggctattcc atttccacgc atgcttcatc
     4381 gcttaaaacc ataatgaacc ctatcagcgt ccgccattgg gcgctttttt gctgcgctga
     4441 gcagtactta gagctcaagc ctcccagtta gacttggcag agctgtggct ctttgcttga
     4501 gctattgtag gcaaaggtat cactggatct gaaaacaaca aaatcagaca agtgatatca
     4561 aaattaaaaa aaaaaaaaaa acgaaaccta ggaggatcgg tgagcttatt agtttggcac
     4621 taatcatcat tatgctataa ttgtcttcac aaataattta gaaatagctc atatttctat
     4681 cattaaagga gagagatgat gaatcgtaaa aagcatacca aactcattcg tcactacagt
     4741 atctgctcag cagtggctgt cctagcagca gttagcttgg gaacaggtca ggacgtacag
     4801 gcttcggaac ccaatccata tccagatgtg aggcgtttcc ttgatgagaa gtacgatgga
     4861 gatgtggata aattatctaa acaacttcaa ggttattttg gtagtttaag agagtatata
     4921 gagtttgaac ttaaaaatgg caaacaaggt cctgctggcc ctcaaggccc aaagggtgat
     4981 aaaggagacc ccggagagcc aggtcctcaa ggtccagtgg gccccgctgg tccaaagggt
     5041 gatcgtggtt tagacggacg acgtggccca gcaggtcagc aaggggaagc cggcccagtt
     5101 ggtcctcagg gtcctcaagg cgagcaaggg ccaaaaggcg accgtggcga acaaggacca
     5161 aagggtgaac gcggtgagca aggaccaaag ggtgaacgcg gtgagcaagg gccaaaaggc
     5221 gaccgtggcg aacaaggacc aaagggtgaa cgcggtgagc aaggaccaaa gggtgaacgc
     5281 ggtgagcaag ggccaaaagg cgatcgtggc gagcaaggac caaagggtga acgcggtgag
     5341 caagggccaa aaggcgatcg tggcgagcaa ggaccaaagg gtgaacgcgg tgagcaaggg
     5401 ccaaaaggcg atcgtggcga gcaaggacca aagggtgatc gtggcgagca aggaccaaaa
     5461 ggtgatcgtg gcgaacaagg accaaagggt gatcgtggcg agcaaggacc aaaaggtgaa
     5521 cgcggtgagc aaggaccaaa aggcgatcgt ggcgagcaag gtccaaagaa ggagccagaa
     5581 aaagacacca agccatcagt gccaaaggca ccagataata tggctgcacc aaaggctccg
     5641 gagaagaaga accctaaagc accggctcct aagtcagctc caaaggcatc attgccatca
     5701 acaggagaca ctagccaatc atttgttgca gcagcccttg gctttatcgc tagcgcgggc
     5761 ttgctagtct tcaaaagaaa gaaaaactaa gctagctaaa gactgtaaac aagcctcaac
     5821 tgttacagca agcctctttg acatcttgca gataagagga tttcttagcg aatgaagtgt
     5881 gtctaaagtc agatactctg ctggactagc agtagctgat ctccctgaaa atcagttatg
     5941 ctaaagcatt gagccttagt tgcaaggctt aggtgtgacc ttccaaagga agctgctttt
     6001 gcctgtatca ctttaggaag atatctaaaa gagacacttt tttcacgctg aagctaagct
     6061 agcttttcct atgacaaata tcctataaca ataaactcca aacaaaagag aggtcaaatg
     6121 gtacctctct tttacttagc tttaggattg atagattcta aaggcttcct tgtttcttga
     6181 tcaagaagtc cttactgata gagtctgtct tagccgggct tatatggtat aatacctaat
     6241 ggagataaga aaagtcctta acaaatagag tttcatctat tgttacagga gcaaccaagt
     6301 gaaaggagat gctacatgtc agataaacaa atcaatttgg ttattgttac aggaatgagt
     6361 ggcgccggca aaacagttgc cattcaatca tttgaggatt tggggtattt tactgttgat
     6421 aacatgccac cagctttagt gcctaaattt ttagagctgc ttgagaggac caatgaaacc
     6481 caaaaggttg ctctggtagt ggatatgcgc agcagacgct ttttcaagga gattaactct
     6541 atcttagatc atattgagct aaatgccaac ctcaagctac ggatcctctt tcttgatgcg
     6601 actgatagtg agctagtgtc acgctataag gaaactagaa gaagtcaccc tctggctgct
     6661 gatggtcggg tgcttgatgg gattcgacga gaaagagagc tgttagtccc gcttaagagc
     6721 atgagtcagc atgtggtcaa taccaccgat ctaaccccaa gacagctgcg taaggtgatt
     6781 tcggatcagt tttcaagcga gtcagaccaa gcctcattta gaattgaggt gatgagcttt
     6841 ggctttaaat atggcctccc cttagatgcg gaccttgtct ttgatgtgcg ctttttgcct
     6901 aatccttatt atcaggtggc gctaagagag cagacagggc ttgatcaggc tgtttttgat
     6961 tatgtgatga ctcatcaaga gtcagaggcc ttttataatc atttgttagg cttgattgtt
     7021 cctattttgc ctgcttatca aaaggaaggc aaatcagtgc taaccattgc tattggctgt
     7081 acaggtggtc agcatagaag tgtcgccttt gcccatcgct tggcccaaga cttgacagca
     7141 gactggccgc tgcatgagag tcatcgggac atcaatcgtc gtaaggaaac ggtaaatcgc
     7201 tcatgagaaa tcctaaaata acggtgatag gaggaggaac aggtattcct gttatcctaa
     7261 aaagccttcg caaggaggcg gttgacatta ctgcggtggt cactgttgct gatgatggtg
     7321 ggtcatctgg taagctgcgc aatgccatgc agcttacccc gccaggtgat ttgcgcaacg
     7381 tcttgttggc catgagtgac atgcctaagt tttatgagcg tgtgtttcag tatcgtttta
     7441 atgaggcaga tggtgctcta gctggtcatc ctctaggcaa tttaattatc gcaggtattt
     7501 ctgagatgca gggatccacc tataacgcta ttcagatttt gacgaaattt ttccatatca
     7561 ccggcaagat ttttccctca agcgagcagc ccttgacact gcatgctgtc tttaaggacg
     7621 gtcatgaggt gtcaggagaa agctctattg ccagctacca aggcatgatt gaccatgtct
     7681 atgtgaccaa tacctacaat gatgacctgc caaaggccag tcgtaaggtg gttgaggcca
     7741 ttctccaaag tgatatgatt gtgcttggtc ctggttcctt gtttacctct attttgccca
     7801 atcttgtaat tccagagatc aaagaagccc tgagagtaac caaggcagag gtggtttata
     7861 tttgtaacat tatgacccag tacggtgaga cagagcaatt ttccgatgcg gatcatgttg
     7921 cggttttaaa tcagcatctg ggcagggact taattgacac tgttttggtt aatgttgagc
     7981 aggtgccaaa aagctatatg aattccaacc aatttgacga atatctggtc caagtagagc
     8041 atgactttgc aggtctgtgt aagaccgcaa agcgtatcat ctcgtctaat tttctgcgtt
     8101 tggagaatgg cggagccttt catgacgggc acttggttgt agaagaatta atgaacctag
     8161 ttaggataac caagctatga gttttacgac aactgttaaa gaagaattga ttcatttatc
     8221 tgcttctgat caaacagaat tatcagcaat catcaagctg gctggtagcc taggcttggc
     8281 taatcagagc ttgaatttgt ctatcacaac tgaaaacgct aagattgctc gctacatcta
     8341 tgcgcttatc gaagacacct atcatatcat tccagaaatc aggtaccatc aaaagaccaa
     8401 cttgaaaaaa aatcgtgtct atacggttta tttggataag caggtggata agctcttagc
     8461 agatttaaag ctggcagatt ctttttttgg cattgagaca ggtattgagc agcaggtcat
     8521 gtcagatgat gatgctggtc gggcctatct caagggtgct tttttagcgg cagggactgt
     8581 aagggatcca gaatccggca agtatcagct agagatctac tctgtctatc tagaccatgc
     8641 tcaggatttg gcccagctca tgcacaaatt catgctagat gccaaggtta tcgagagaaa
     8701 aaatggtgca gtaacctatt tgcaaaaggc tgaggacatc atggattttc tcattattat
     8761 tggtgccatg tcgtgtaagg aggagtttga ggctgttaag cttttgcgtg aggcgagaaa
     8821 tgacatcaat cgggccaata atgcagagac tgctaatatt gctaaaacca tcaccgccag
     8881 catgagaacc attaataata ttatcaaaat catggatacg attggcttag acagcctgcc
     8941 agttgagctg cagcagattg cccagatgag agtagccaac ccagactatt ctcttcaaca
     9001 aatcgcagat tcgcttgact ttgccatcac taagagtggg gtcaaccatc gcctgcgaaa
     9061 aatcaataag ctggcagagg atttataaag acagcttagc ctttttcagg ctgataaaaa
     9121 agggggtaag gtgatacgaa caagccgcct tttaaggcat gccttgttga gctttctcta
     9181 ggctgttgat ggagtgatct caaggcgctt ttgttactgt cattccaaca ggctatctga
     9241 ttttgggatg acttcttact aataagcttt tctaatggct ggctgacaac gattagcgat
     9301 atagttaagg cttatcgtga ttcaacaaga ggctttagtc tcttttttgc ttgtcagaat
     9361 tattttttta ggcttttctt acaaatgaga ggacaatgtg acaatctgtg gtatgatatt
     9421 agtaatgaat acaaaggaga acaaatcatg tcatgcacaa ctattcttgt cggtaaaaaa
     9481 gcgacctatg atggatcaac aatcgttgct cgtacagagg attcacaaaa tggggaattt
     9541 acccctaaaa aaatgacagt tgttagacca aaagaccaac ctagacacta tcaatctgtc
     9601 ttgtctagct ttagcatgga gctgccggat cagccgatgg cttatacctc ggtgcctgat
     9661 gccctaggaa aggacggtat ctggggagaa gcaggtgtca ataccctcaa tgttgctatg
     9721 tcagcaactg agaccattac ttcaaatgct cgcgttcttg gagcagatcc tcttgtttcc
     9781 tctggtattg gagaagagga catgctgacc ttggtgcttc cttatattcg gtctgcaaga
     9841 gagggtgttc ttcgtttggg agctatccta gaagcatacg gtacctatga ggctaacggt
     9901 gttgcctttt ctgatgagca tgagatttgg tggctggaaa caataggtgg tcatcattgg
     9961 attgcaaggc gcgttcctga tgatgcttat gtcactaatc ccaaccagtt tggccttgat
    10021 cactttgaat ttaacaatcc agaggaatac ctgtgttcca aggatttaaa ggactttatt
    10081 gccaaatatc atctagattt gacctatagc aacgagcatt ttaaccctcg ctacgccttt
    10141 ggtagccaaa gagataagga tcgccattac aatacaccac gcgcttggat tatgcagcaa
    10201 tactttaatc cggagtttct gcaggatccg cgcagctttg aacttccttg gtgccaaaga
    10261 cctgatcgca aggtgaccat tgaagacgtt aagtacgtgc ttagcaatca ttatcaggac
    10321 accccttatg atccttacgg cccagaggga acgccgacta gtcgaaaatc ctttaggccg
    10381 attggtatta accgtacgag tcaaactgct attttacata tccgtcccaa caagcctaag
    10441 gaaattgctg ccattcagtg gatggcctat ggttcgatgc cctttaatac aatcgttccg
    10501 ctattcaccc aggtcaagac cattccagat tattttgcaa acactgttga aaatgtttcc
    10561 acagacaatt tctattggac caatcgcttg attgcagccc tggctgatcc tcacttcaag
    10621 caccatgaag cagatttgga ggactatctc gaaaaaacaa tggccaaggg tcatgccatg
    10681 ctgcatgctg ttgaagcagc gctagtaaaa ggtcagccgg ttgacctaga agaggccaac
    10741 caaggcatga gtgatgacat tcaggcagat acacaggctc tgctcaataa gatcctcttt
    10801 gatgctagca atctcatgac caaccgcttt agcctaagcg actaagtaat ctcaatagtc
    10861 aaacgagctc atatcattat agatatgggc tcttagcttg aaaaggatag tagagcggtc
    10921 ttatagtcag actaattaat ggtaacgatg agtccagtta aggtaaaaaa agagcactta
    10981 gctaatgcaa aaaaagtaaa aaacttgcaa aagaatgata ttgtgttata cttaaccagt
    11041 aaatattaag agctatttgc gatatgatat atagaggagg aatcatgaaa aagaagtatc
    11101 ttttaatgat gagtgtgctc ggtgtctttt ttgcgggaca gatcagtcaa gcaaaacagg
    11161 tcctagcaga tagtaaggtc aaaattgtta ccaccttcta tcctgtttat gaatttacca
    11221 aaggcgttgt cggaggtgag ggaaatgtgt ctatgctgat gaaagcagga acagagcctc
    11281 atgattttga gccgtcaaca aaggacatca aaaagatcca agatgccgat gcctttgttt
    11341 atatggacga taatatggaa acttgggtcc ctgatatgaa gaaatcactg acttctaaga
    11401 aggttacggt gattaaggga acaggagata tgctattggt agctggctct ggtcacagcc
    11461 acgagcatga ccatgacgat gccgataaaa agcatgatca tgaccacgac gaggaaggac
    11521 acagccatgc ttttgacccg cacgtatggt tgtcacctta tcgcagcatc accgttgtcg
    11581 aaacaattcg tgatggtcta tctaaggcct atcctgacaa ggctgaccac ttcaaatcta
    11641 atgccgctgc ttatattgaa aagctcaagg aattagataa ggagtatagt gacgcttttt
    11701 cagctgccaa gcaaaagagc tttgtgactc agcacgcagc ctttggttat atggcgcttg
    11761 attatggctt gaaccaaatc tcaatcaatg gtgtcacacc agatacggag ccttcagcta
    11821 agcgcattgc agagctatca aaatacgtca aaaaatatga cattaactac atttattttg
    11881 aagaaaatgc ttcaagcaag gttgccaaaa ccctagccaa ggaggctggt gtcaaatcag
    11941 ctgtccttag tccgcttgaa ggcctaactg aaaaggacat gaaggccggc aaggattact
    12001 ttaccgttat gcgtgaaaac ctcaaaaccc tacgcttaac aactgatgta gaaggaaaag
    12061 aaattcttcc agaagaggat accactaaaa ctgtttataa tggctacttt aaggataagc
    12121 aggtcaaaga ccgcaaattg tctgattggt ctggtaactg gcagtctgtt tacccattcc
    12181 ttcaagacgg tacattagat caggtatggg actataaggc taaaaaatct aaaggaaaaa
    12241 tgaccgcagc tgaatacaag gattattaca ccactggcta tcagacagat gtcagtcata
    12301 tcaagattaa tggtaagaaa aataccatga cctttgttcg taatggtgaa aataaaacct
    12361 ttacttataa gtacgtcggt aaaaagattt tgacctatcc aaagggcaat cgtggcgtgc
    12421 gcttcatgtt tgaagctaag gagccagacg ctggtgaatt taaatatgtt cagttcagtg
    12481 accatgctat cgcgccaggt aaggcggagc atttccacct atactggggt ggtgacagcc
    12541 aagaaaagct tcacaaagag ctagagcatt ggccaactta ctatgatgcg gacctatcag
    12601 gtcgtgccgt tgcccaagaa atcaatgctc attaaccact caaaagacta ggcagttcaa
    12661 tcggcctagt tttttcttgt cttagttgct gtataggacc taaatgctga tagctggtct
    12721 taagattta
//
LOCUS       DARYXW010000059        12358 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.059, whole genome shotgun sequence.
ACCESSION   DARYXW010000059 DARYXW010000000
VERSION     DARYXW010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12358)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12358)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12358
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.059"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(43..2631)
                     /gene="hylB"
                     /locus_tag="TV191_001352"
     CDS             complement(43..2631)
                     /gene="hylB"
                     /locus_tag="TV191_001352"
                     /EC_number="4.2.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_192884538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronate lyase"
                     /protein_id="HEL1507858.1"
                     /translation="MATGTEKKHQEKLYIPKLKVNQIKLELFYEAGHGQVVFDNLSLR
                     EAGDKPSDDIKIASHYLEEQIVLPLNKHYLMEMADYHYQIAAESSNIVRVENGLLIPL
                     AQGKTLLEVLDQEGQRVATVPVEILAAEAPQTTSLITKWCEVILGAENFDRSSPAMVA
                     LNQKLDDSVTKNLADLTKDQKSTYLWSDLADLHQSSHMTATCRRLEEMAKQVSSLASR
                     YYQDKELIRLIKDKLAWLTLNYYHPQKDIEGKANWWDFEIGTPRAIVNTLAFIYPYVT
                     QEEIKRYTKGISHFVPNPRQFRLTLVNPFKAIGGNLVDMGRVKIIEALLKHDKKALQD
                     SIAALDTLFAFQPKGSRGEGFYEDGSYIDHTNVAYTGAYGNVLIDGLSQLVPLLQLLA
                     TSLDQQKLEVMTHWIEQAFLPLMVHGELMDMSRGRSISRENASSRQAALEALRGMLRL
                     AEALPEQAKIRIKGKIKAVLAFHNQETILESLSSYYDMKLFKELLEDTTIQASPVKSY
                     LSLFNQMDKLAYYNAEKDFAFALSMHSNKTLNFEAMNDENTRGWYTGDGMFYLYNSDL
                     GHYSDHFWPTVNPLKMAGTTEAEVRREDVTVAYLKKLTNDYKEKAKEKAGMSTLPSSF
                     VGAIKAGDKTALAVMDFQNWDRTVSAKKSWTILDDQIVFLGTAITSQTHQAVTTTIDQ
                     RKENPDNSYTLFINGQETALTEEILYRDDVTSLLLLSKDGQANIGYLFAKPTALALSR
                     KVQSGCWSEINTNSNNKDLISQSFITISQTHSQASDSYAYTLLPNISKADFDKVCSEA
                     RIEVLRNDSKLQLIHDKKQGLLAVVKYNQAKEVVNGQLSLEKSGLYLYQKVGNDFKQL
                     SFKALS"
     gene            complement(2577..3230)
                     /locus_tag="TV191_001353"
     CDS             complement(2577..3230)
                     /locus_tag="TV191_001353"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507859.1"
                     /translation="MKQRKKLSSSVCSSIILACLFRAPTVLAEEKTAAKAISKELQRV
                     KKAPLKTEEASQESSPDTQDASSVATESSLGEQLILTGDNLLKNPQFDQTSPAQEHQS
                     TSLWSKESANDWKDYKDASKSQGCPKIAVSDNKLTMTSDGNQRFRGCVHQTVAINPDK
                     QYLLTFDIETKDKTGQAFARIIEEIKQGSGAAKEQRLWLRWQQELRKNTKKSFISLS"
     gene            complement(3270..3899)
                     /locus_tag="TV191_001354"
     CDS             complement(3270..3899)
                     /locus_tag="TV191_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEL1507860.1"
                     /translation="MRKSEIMLRLKANKLALVVRGASKKEAMACSLAGIEGGIKTIEV
                     AYTNPFASQVIAGLREAVGNDPEILIGAGTVLDDVTARLAILAGAQFIVSPSFSRQTS
                     RLCHRYAIAYIPGCMTIEEVVTALESGAEMVKVFPGATVGMSFIKAIKSPLPQVDVMV
                     TGGVTVTNVSDWFAAGAQVLGVGGEFNQLAAQGQFQAITARAADYMSSC"
     gene            complement(3901..4902)
                     /locus_tag="TV191_001355"
     CDS             complement(3901..4902)
                     /locus_tag="TV191_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEL1507861.1"
                     /translation="MTKVLLVGEPLIRISPSHFQTLGHACQAQLYYGGSEVNIARTLS
                     GFRAESSLLTALPDNQVGRSVEAFLKQSGVATEHVQWCGDRVGIYYLENGFGCRPSQV
                     AYDRSASSFSLLGPKDLDYGKLFEEVTHFHFSGITLALGKVSQDLVEQLAIEAMKRQV
                     CVSFDLNFRSSMISVREAKTLFSHFAQYADLIFGMEPLMCNQADHAMFDRAKAGQGAV
                     KERLAALYEAYHLKAIFHTERHIDDQGINHYLAYAYDGQLHRSIELSTPVLQRVGSGD
                     AFVAGCLYQLMRGQAIAAALDFAAATASLKCTVADDQLFVPVSQVDRVMKGNREVRR"
     gene            complement(4935..5576)
                     /locus_tag="TV191_001356"
     CDS             complement(4935..5576)
                     /locus_tag="TV191_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEL1507862.1"
                     /translation="MKIALINENSQAAKNSIIYETLVSVTNKHGYEVFNYGMYGKEGE
                     SQLTYVQNGLLASILLTSKAADFVVTGCGTGVGAMLALNSFPGVTCGFASEPTEAYLF
                     AQINGGNALSIPFAKGFGWGAELNLTLMFERLFAEPMGGGYPKERAIPEQRNARILSE
                     LKAVTYRSLLEVLKEIDQDFLKETISGEHFQHYFFANAEPSDLVDYLREVLQQ"
     gene            complement(5611..6405)
                     /locus_tag="TV191_001357"
     CDS             complement(5611..6405)
                     /locus_tag="TV191_001357"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEL1507863.1"
                     /translation="MEHFFSLEGKIALITGASYGIGFEIAKAYAMAGAKIVFNDIKQD
                     LVDQGLAAYREFGIKAHGYVCDVTDEVGIQEMVAQIEKEVGIIDILVNNAGIIKRTPM
                     LEMTAKDFRQVVDIDLNAPFIVSKAVLPSMIKKGHGKIINICSMMSELGRETVSAYAA
                     AKGGLKMLTKNIASEFGEANIQCNGIGPGYIATPQTAPLRERQADGSRHPFDQFIIAK
                     TPAARWGTPADLAGPAIFLASEASNFVNGHILYVDGGILAYIGKQP"
     gene            6714..7148
                     /locus_tag="TV191_001358"
     CDS             6714..7148
                     /locus_tag="TV191_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEL1507864.1"
                     /translation="MISIIVIGHGHFASGIVSSLELIAGKQEGITAIDFTAEMTAADV
                     HERLSVVLQSKTQALMLCDLLGGTPFKVAATLMEELSESTLDVLSGLNLAMLIEAVFA
                     RQEQLDLEQIVAKLLTTAKEGISNWKSLSGEADEADLDEGGI"
     gene            7148..8347
                     /locus_tag="TV191_001359"
     CDS             7148..8347
                     /locus_tag="TV191_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEL1507865.1"
                     /translation="MTRQIKEVTLEPLIQAEVYSQQPYLTKADIEAAILLALKQIRLN
                     MDYFGTDFPRPATKDNCYPIMDNTEWTNGFWTGCLWLAYEYTGNDTIKSLAQANDLSF
                     LERVTKDIELDHHDLGFLYSPSCMAEWKLLKTPEARQAALKAADKLIERYQEKGGFIQ
                     AWGQLGKAEDYRLIIDCLLNIQLLFFASQETGDDRYRQMAINHFYASANNVIRDDASA
                     YHTFYFDPETGDPIKGVTRQGYSDDSAWARGQAWGIYGIPLTYRFLKDPQLIALFKGM
                     THYFLNRLPKDQVSYWDLIFEDGSGQSKDSSATAIAVCGIHEMLKHLPENDPDKKAYQ
                     AAMHCMLRSLIDSYANKDIKPGAPLLRHGVYSWHSGKGVDEGNIWGDYYYLEALLRFY
                     KDWTPYW"
     gene            8393..8881
                     /locus_tag="TV191_001360"
     CDS             8393..8881
                     /locus_tag="TV191_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEL1507866.1"
                     /translation="MTPPNIIMTRVDERLIHGQGQLWIKFLNCNTVIVANDAVAEDKI
                     QQSLMKPVVPSSIAMRFFSIQKVIDVIHKASPAQTIFIVVKDLEDIKRLVEGGVPIKE
                     VNLGNIHKTDDKIAITQFISLGDKDKAIIRTLTHDHHIVFNTKTTPAGNGASEVNILD
                     YI"
     gene            8896..9675
                     /locus_tag="TV191_001361"
     CDS             8896..9675
                     /locus_tag="TV191_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEL1507867.1"
                     /translation="MDINLLQALLIGLWTAFCFSGMLLGIYTNRCIILSFGVGIILGD
                     LPTALSMGAISELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVTPEAALALST
                     PIAVAIQFLQTFTYTAFAGAPETAKKQLQKGNIKGFTFAANGTIWAFAVIGLGLGLLG
                     ALSMDTLLHLVDYIPPVLLNGLTVAGKMLPAIGFAMILSVMAKKELIPFVLIGYVCAA
                     YLQIPTIGIAIIGIIFALNEYYNKPKHATTAEQGGQQDDWI"
     gene            9662..10483
                     /locus_tag="TV191_001362"
     CDS             9662..10483
                     /locus_tag="TV191_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEL1507868.1"
                     /translation="MTGSNKLTKRDYLKTALRAFFLQNGFNYSNYQGIGYANVVYPAL
                     KKHFGNDKTGLYKALENNCAFYNTNPHFLPFITSLHLVMLENNRPEEETRNIKMALMG
                     PLAGIGDTLTQFCLAPLFSTIAASLASDGLILGPILFFLAMNIILTAIKIGSGLYGYK
                     VGTSFIDKLSEQMAIVSRMANIVGVTVIAGLAATSVKISVPITFAAGKVDAANAAQKF
                     VTIQGMLDKIAPALLPALFTLLMYYLIKTKKWTTYKLVILTVIIGIVGSWLGVLA"
     gene            10883..11884
                     /locus_tag="TV191_001363"
     CDS             10883..11884
                     /locus_tag="TV191_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1507869.1"
                     /translation="MQRKVTINDIADLAKTSKTTVSFYLNGRFDKMSQETKSRIKEAI
                     EATNYKPSIAARSLNAKATKLIGVVIGDITNSFSNQIVKGIESKAQEFGYQIIIGNSN
                     YDPSREDELIEKMLNLGVDGFIIQPTSNFRKYSRIIEVKKKRMVFFDSQLYEHRTNWV
                     KTNNYDAVYDTIQQCITKGYQSFIMVTGNPNLLSTRIERASGFIDVLEANQLQYRQMI
                     IDENQTSSQEIAQFLQGAFDKERHNLVFVPNCWALPKVFTAMKALKVSLPETGLVGFD
                     NIEWTRLSSPSITTIIQPAYEEGEQATSILIDDIEGHSKEAKQQIFDCQVNWQESTF"
BASE COUNT         3477 a         2844 c         2448 g         3589 t
ORIGIN      
        1 gctcaggggg gattttaact tattactaat gtgcttgaat ggctatgata aggccttaaa
       61 agatagctgc ttaaagtcat ttcccacctt ttgatagagg tataagcctg atttttcaag
      121 actcaattga ccattaacca cctccttagc ctgattgtat ttgaccaccg ccaacaggcc
      181 ttgtttctta tcatggatca gctgaagctt actgtcattt cgaagcacct caatacgtgc
      241 ttcgctgcac accttgtcaa agtctgcttt gctgatattt ggaagtaggg tgtaggcata
      301 gctatcacta gcctgagaat gagtttgact gattgtgata aagctttggg agatgaggtc
      361 tttattgtta ctatttgtat taatctcaga ccaacagcct gactgcacct ttcgcgatag
      421 cgctaatgcg gttggcttgg caaaaaggta accaatatta gcttgaccgt ctttagaaag
      481 tagtaaaaga ctggtcacat catctcgata caggatctcc tctgttagcg ctgtctcctg
      541 cccattgata aaaagagtgt agctgttgtc tgggttttct ttgcgttgat caatggtagt
      601 agtcactgcc tgatgtgtct gactagtgat ggcggtgcca agaaaaacaa tttggtcatc
      661 taagatcgtc caagacttct tggcactcac tgtcctatcc caattttgaa aatccataac
      721 agctaaagct gttttgtctc ccgccttgat cgctccaaca aaggacgatg gcagggtaga
      781 catgcctgct ttttctttgg ccttttcttt ataatcattg gttagctttt ttaaataggc
      841 tactgtcacg tcctctcgcc tgacctctgc ttccgttgtt ccagccatct ttaaaggatt
      901 aacagtcggc caaaagtggt ctgagtaatg acccaaatca ctgttataaa ggtaaaacat
      961 gccatctcct gtataccaac cacgtgtatt ttcatcgttc atggcttcaa aattcagagt
     1021 tttgttggaa tgcatggata aagcaaaggc aaaatccttt tccgcattgt agtaggccaa
     1081 tttatccatc tggttaaaaa gagataggta gctcttaact ggactggctt ggattgtggt
     1141 atcctccaag agctctttga atagcttcat gtcatagtag cttgataggc tctctaaaat
     1201 agtctcctga ttatggaagg ccaaaacagc cttgatctta cccttgatcc tgattttagc
     1261 ttgctctggc aatgcctcag ccagtcttag cattcctctt agtgcttcta aggctgcctg
     1321 ccttgaggag gcattttcac gactgatgga gcgcccacga ctcatatcca tgagctcccc
     1381 atgaaccatc aagggcaaga aggcttgctc aatccaatga gtcatgacct ctagcttttg
     1441 ctggtctagg ctagtagcta atagctgaag taatggtacc agctgagaca agccatcaat
     1501 aaggacattg ccataggctc cagtgtaggc gacattggta tggtcaatat aagagccatc
     1561 ttcataaaag ccctcacccc ttgatccctt tggctgaaaa gcaaataagg tatctagggc
     1621 tgctatactg tcttgaagcg ctttcttatc atgctttaac agagcttcaa taatcttcac
     1681 tcgtcccata tcaacaaggt tacccccaat ggccttaaaa ggattcacaa gggttaagcg
     1741 aaattgtcta ggattaggaa caaagtgaga aattccttta gtatagcgct tgatctcctc
     1801 ttgagtgaca taagggtaaa tgaaggctag ggtattgaca atagctcttg gggtaccaat
     1861 ttcaaaatcc caccaattag ccttgccttc aatatccttt tgcggatgat agtaattaag
     1921 tgtcagccag gctaatttat ccttgatcag tcttatcagc tccttatcct gataatacct
     1981 agaggctagg ctactcacct gcttggccat ttcctctaaa cgcctacagg tagctgtcat
     2041 atgagacgat tgatgaagat ccgccaaatc actccaaagg tatgtgcttt tctgatcctt
     2101 ggtcagatca gctagattct tggtcacgct gtcgtccagt ttttggttta atgccaccat
     2161 ggctggactt gatcggtcaa agttttctgc tcccaaaatc acctcacacc actttgtgat
     2221 caaggaggtt gtttgagggg cttctgctgc taaaatctca actggtaccg ttgctactct
     2281 ttgcccctct tgatccaaca cctctaaaag cgttttcccc tgcgccaaag gaattaaaag
     2341 accattttcc acgcgcacaa tgttgctgga ctccgctgca atctgataat gatagtcagc
     2401 catttccatg aggtagtgct tatttaaagg caggacgatt tgctcctcta agtaatgtga
     2461 agcaatcttg atgtcatcac ttggcttatc accagcctct ctcaaagaaa ggttatcaaa
     2521 gaccacctgt ccatgaccgg cctcataaaa gagctctagc ttgatttgat taacctttag
     2581 cttagggata taaagctttt cttggtgttt tttctcagtt cctgttgcca tcgaagccac
     2641 aagcgttgct cttttgcagc accagaacct tgctttattt cttcaatgat acgcgcaaaa
     2701 gcctgacctg ttttatcctt tgtctcaatg tcaaaggtca gcaaatactg cttgtctgga
     2761 ttgatggcaa cggtttggtg cacacagcct ctaaatctct gattgccatc gctagtcatt
     2821 gtcagcttgt tatcagagac agcaatttta ggacagccct gactcttact agcgtcctta
     2881 taatccttcc aatcatttgc agactccttg ctccaaaggc ttgtactttg atgctcttga
     2941 gcaggactgg tctgatcaaa ttgaggattt ttaagcaggt tatcacctgt gagaatgagc
     3001 tgctccccaa gactggattc cgtagctact gacgacgcgt cttgagtgtc tggggagctt
     3061 tcttgagaag cctcctcagt ttttagtggt gctttcttta ccctctgaag ctccttggaa
     3121 atggcttttg ctgctgtttt ttcttctgct aagactgttg gtgcccgaaa taaacaagct
     3181 agtatgatac tagagcaaac agaagatgat agtttttttc tttgcttcat ctgatacctc
     3241 cttgcttttt taatgtttta tgaccgactt taacagctac tcatgtaatc tgcagccctt
     3301 gctgtgattg cctgaaattg accctgagct gccaattgat taaattctcc tccaactccc
     3361 agcacctgag cacctgcggc aaaccagtct gacacatttg tgacagttac gccacctgtt
     3421 accatgacat caacctgcgg caaaggagat ttgattgcct taataaagga catgccaact
     3481 gtggcacctg gaaagacctt gaccatctct gcacctgatt ccaaggcagt cacgacctcc
     3541 tcaatagtca tacagcccgg aatataagca atagcatatc gatgacatag gcggcttgtc
     3601 tgcctgctaa agctaggaga cacaataaat tgagcacccg ctaaaatagc tagccttgct
     3661 gtgacatcat caagaaccgt cccagccccg atcaggatct ctggatcatt gccaactgct
     3721 tcacgcaggc ctgcaataac ctgactggca aagggattag tataggccac ctcaatggtt
     3781 ttgatcccac cttcaatacc tgctaggctg caagccattg cttctttttt agaagctccc
     3841 cgaacgacta aggctaattt attggctttt agccttaaca tgatttctga ttttctcata
     3901 ttaccttctt acctctcggt ttcccttcat caccctatca acctgactaa caggaacaaa
     3961 gagctgatca tcagcaactg tacacttaag actagctgtc gcagcagcaa aatcaagcgc
     4021 agcagcaata gcctgtcctc tcatcaattg atataagcag cctgcaacaa aggcatcacc
     4081 actgccaact cgttgcaaaa caggcgttga tagctcaatg gagcgatgta actgcccatc
     4141 ataggcatag gctaggtaat gattgattcc ttggtcatcg atgtgacgtt ccgtgtgaaa
     4201 aatggctttt aagtgatatg cctcatataa ggcagccaag cgctccttga cagcaccttg
     4261 acctgcctta gctctatcaa acatggcatg atcagcttga ttacacatta agggctccat
     4321 accaaagatc aggtctgcat actgtgcaaa atgagagaac aatgtctttg cctccctgac
     4381 tgaaatcatc gagctgcgaa aattcaaatc aaaggaaaca cagacctgcc gcttcattgc
     4441 ctcaatagcc agctgctcaa caaggtcctg actgactttt cctaaagcca aggtaatgcc
     4501 actaaaatga aaatgagtaa cttcctcaaa tagtttacca taatccagat cttttgggcc
     4561 caataaacta aagctagagg cagagcgatc ataagcgacc tgactaggac ggcagccaaa
     4621 gccattttcc aaataataaa taccaacccg atcaccacac cattgcacat gctctgtggc
     4681 aacaccgctt tgcttcaaaa aggcctcaac gcttcgtcca acctgattat caggaagggc
     4741 agtcagcagg ctactctctg ctctaaagcc actaagcgtt cttgcaatat taacctctga
     4801 gccaccataa tacagctgtg cttgacaggc atgtcctaac gtctgaaaat gactgggact
     4861 gatgcgaatc agcggctctc ccaccaataa taccttggtc ataggggtat cctttctata
     4921 gctgcagata agacttattg ctgaaggact tctcttaggt agtcgacaag gtctgatggc
     4981 tcggcattag caaagaaata atgctggaag tgctctccag aaatggtttc cttcaagaaa
     5041 tcttgatcaa tctcctttaa cacctccaac aaagaacgat aagtcacagc cttcaattcg
     5101 ctcaaaattc tagcgttacg ttgctctggg atggcccgct ctttgggata gccgcccccc
     5161 atcggctcag caaataagcg ctcaaacatc agggtcaggt taagctctgc cccccaacca
     5221 aagccctttg caaatggaat agacaaggca ttgccaccat taatctgagc aaaaaggtag
     5281 gcttctgttg gctcactagc aaagccacag gtcacacctg gaaagctatt taaggccagc
     5341 atagcaccca caccagtccc acagcccgtt acaacaaaat cagctgcctt acttgtcaat
     5401 aaaatagaag ctagtagccc gttttgcaca taggtcagct gactttcgcc ctccttgcca
     5461 tacataccat agttaaagac ctcatagcca tgcttattag taacagagac taaggtctcg
     5521 taaataatac tgtttttagc tgcttgactg ttttcattaa ttaatgcaat tttcatcttc
     5581 tgtaatctcc tttgatgctt ttttgtttct ttacggttgt ttgccaatgt aagctaaaat
     5641 gcctccatca acataaagga tatgcccatt gacaaagtta ctcgcctcac tagccaaaaa
     5701 tatagctgga ccagccagat ctgctggtgt tccccaacgc gctgccggag tcttagcaat
     5761 aataaactga tcaaaggggt gacggctgcc atcagcctga cgctctctta aaggtgctgt
     5821 ctgaggcgtt gcaatatagc caggcccaat gccattgcac tggatattgg cttctccaaa
     5881 ttctgaagcg atgtttttgg ttaacatctt aagaccaccc ttagctgccg cataagcact
     5941 aaccgtttca cgaccaagct cactcatcat cgaacagata ttgatgattt tcccatgccc
     6001 ttttttaatc attgatggca gaactgcctt tgaaacaata aatggcgcat tcaggtctat
     6061 atctaccacc tgacgaaaat ccttagccgt catctcaagc atcggtgtcc gtttaatgat
     6121 acctgcatta ttcacaagaa tatcaataat accaacctct ttttcaatct gagccaccat
     6181 ctcttgaatc cctacttcat cagtgacatc acaaacatag ccatgagctt taatgccaaa
     6241 ctctcgataa gctgctaatc cttgatccac taaatcctgc ttgatgtcat taaagacgat
     6301 ctttgctcca gccatggcat aggccttagc aatctcaaag ccaatcccat acgaggctcc
     6361 cgttatcaag gcaattttgc cctctaaaga aaagaaatgt tccattgttt tacctctcaa
     6421 tctcaatatt taagtaaacc tgtttatcaa aactatagca agactaatcc attttgtcaa
     6481 tcattttagt aaaaacacaa aaaagagcta aagtttttct tattgtcatt atcgaggaag
     6541 gcttcttagc tatatttttc ttgctcttac tcgctttact tcctataagg atcccaaaaa
     6601 ttaggccata ttgatcgctt attttgataa aataacaaaa aagtgttgac aaacattttt
     6661 gaaagcgcta taatttttct gagtaaatcg gtaaactaaa aaggagctta ttcatgattt
     6721 ctattattgt tattggtcat gggcattttg ccagtggtat tgtctcgtct ttagagttaa
     6781 ttgcaggcaa gcaagagggc ataactgcta ttgattttac tgctgagatg accgctgctg
     6841 atgtgcatga gcgcctatca gtagtcttac agtcaaagac tcaggcactt atgctttgtg
     6901 acttattagg cggcacccca tttaaggtag cagctacctt gatggaggag ctttctgaga
     6961 gcacacttga tgtcctgtct ggactcaatc tagccatgct aatagaagca gtctttgcta
     7021 ggcaagagca gcttgatcta gaacaaattg tcgctaagct attaaccaca gccaaggaag
     7081 ggatcagtaa ttggaaatcc ctctctggtg aggctgatga agcagacctt gatgaaggag
     7141 ggatttaatg actagacaga tcaaagaggt tacccttgag cctctcatac aagcagaggt
     7201 ctatagccag cagccatatc taacaaaagc tgatattgag gcagctattt tattagccct
     7261 taagcaaatc cgattaaaca tggattattt tggtactgat ttccctaggc cagccactaa
     7321 ggacaattgc tacccaatta tggataatac cgagtggacc aatggctttt ggaccggctg
     7381 cctatggctg gcctacgaat acactggtaa tgacactatc aagtcactag cacaggcaaa
     7441 tgacctgtcc ttcttagaac gcgtcaccaa agacattgag cttgaccatc atgatttagg
     7501 atttctttat tcaccctctt gcatggctga gtggaagctt ttaaaaacac ctgaagccag
     7561 acaggcagcc ttaaaggcag cagataaatt gattgagcgc tatcaggaaa aaggcggctt
     7621 tattcaagcc tggggacaac tcgggaaagc agaagattac cgcttaatta ttgattgtct
     7681 tttaaatatc cagctactct tttttgccag tcaagaaaca ggagatgaca ggtatcgtca
     7741 aatggctatc aatcactttt atgcctcagc caacaatgtg attcgtgatg acgcctctgc
     7801 ttatcatacc ttctactttg accctgaaac aggtgatcca atcaaaggag ttacacgcca
     7861 aggctacagt gatgactccg cctgggccag aggacaagct tggggaatct atggaattcc
     7921 cttgacctat cgcttcttga aggatccaca gctaattgcc ttatttaaag gaatgacgca
     7981 ctatttcctc aatcgcttgc ccaaggatca ggtatcctat tgggatttga tctttgaaga
     8041 tggcagtggt cagtctaagg acagctccgc aactgctatt gctgtttgtg gtattcacga
     8101 gatgttaaaa catttaccag agaatgatcc tgacaagaaa gcttatcaag ctgccatgca
     8161 ctgtatgctc agatcattaa ttgatagcta tgccaacaag gacatcaagc ctggtgctcc
     8221 acttttacgt catggcgttt actcttggca ctctggcaag ggcgttgatg agggaaatat
     8281 ctggggagat tactactatt tagaagccct gctgcgcttt tacaaggact ggacccctta
     8341 ttggtaggct gatagcattt agcctacaaa gactattgtt aaaggagata ttatgacacc
     8401 accaaacatt atcatgacca gagttgatga gcgtttgatt catggtcaag gccagctatg
     8461 gatcaaattt ttaaattgca acactgtcat tgtggctaat gatgccgttg ctgaagacaa
     8521 aatccaacag tctctgatga aacctgtcgt tccatcaagc attgccatgc gctttttttc
     8581 cattcaaaag gtgattgacg tgattcacaa agcaagccct gctcagacaa tctttattgt
     8641 tgttaaggat ttagaagaca tcaagcgctt ggttgaagga ggggtgccca ttaaagaggt
     8701 caatcttgga aacattcata aaacagacga taaaatcgcc attacccaat tcatttcgct
     8761 aggcgacaag gacaaggcta ttattcggac attgactcac gatcatcata ttgtctttaa
     8821 cactaaaaca actccagctg gcaatggtgc ctctgaggtt aatattttag attatattta
     8881 agaaaggaaa ttgatatgga tatcaatttg ttacaagcac ttttaatcgg tctttggaca
     8941 gccttttgtt tcagcggaat gttacttggt atctacacca atcgctgtat cattctgtct
     9001 tttggtgtcg gcattatctt gggggacttg ccaacagcac ttagcatggg agctatatct
     9061 gaattagctt atatgggatt tggtgtcggt gctggtggta ctgtgccacc caacccaatc
     9121 ggacctggta tctttggtac cttgatggct attaccagtg ctggtaaagt tactccggaa
     9181 gctgccttag ctctttcgac accaattgcc gttgctattc aatttcttca aacctttacc
     9241 tatacagctt ttgctggtgc tcctgaaaca gctaaaaaac agcttcaaaa agggaatatt
     9301 aaaggcttta catttgccgc caatggtacc atctgggctt ttgctgtgat tggcttagga
     9361 cttggtttat taggcgcctt gtcaatggat actttacttc atttggttga ttatatccca
     9421 cctgtcctcc taaatggatt aaccgttgct ggtaaaatgc ttcctgctat cggttttgct
     9481 atgattctat ctgttatggc taaaaaagag ctgattcctt ttgtcttaat tggttatgtc
     9541 tgtgcagctt acctgcaaat tccaaccatc ggtattgcca tcataggcat tatcttcgcc
     9601 ctaaatgaat actacaacaa accaaagcat gcaacaacag ctgaacaagg aggtcaacaa
     9661 gatgactgga tctaataagc tcacaaagcg tgattatctg aaaactgctc ttagagcctt
     9721 tttcctgcaa aatggcttta actatagcaa ttatcaagga ataggctatg ccaatgtcgt
     9781 ttacccagcc ctaaaaaagc attttggcaa tgacaaaaca ggcctttaca aagcactaga
     9841 gaacaattgt gcattttaca atacaaaccc tcatttccta ccttttatca ccagcctaca
     9901 cctggtcatg ctagaaaata atcggcctga agaagaaacc cgcaatatca agatggcact
     9961 catgggacct ctagcaggca tcggggatac ccttacgcaa ttttgtttag caccactctt
    10021 ttcgaccatt gctgcttcct tagcaagtga cggcctgatt ttggggccaa ttctcttttt
    10081 cctagccatg aatattattc taacagctat taaaattggc tctggactct atggctacaa
    10141 ggtggggaca agctttattg ataaattaag cgaacaaatg gcaattgtat ctcgcatggc
    10201 aaatattgtc ggagttacag tgattgctgg tctagctgct acttctgtta agatatctgt
    10261 tcccatcaca tttgcagcag gcaaggtcga cgctgcaaat gcagcccaaa aatttgtgac
    10321 cattcaggga atgctggata agattgcacc agctcttctg ccagccctct tcactctctt
    10381 gatgtattac ctcattaaaa cgaaaaaatg gacaacctat aaattagtta ttctaacagt
    10441 tattattggt attgttggca gctggttagg ggtgttagcc tagcagtctt agagattctg
    10501 ttaatcagta ttggagggtc tccattagcg atgagcaggt ctcttttcta ttgggcaaag
    10561 ctaagcattg acaccatcaa ctctcgtagc ctcagtcagg tcttttgccc tgtagagcct
    10621 ttaagcacaa gcctttactg ctagctgtga tgaaggcgtc ctccttctac tggcttctgg
    10681 cacaattaat cctttatatc tctacaagca catgatttag cggctgattg cgcgccaatc
    10741 ttacagaagg tcgcaactta agaaagagta ggatcatttt tgacctcttc aaaggtcata
    10801 ttcttggact gaaatattaa aacaattacc attccatatg ttataataaa actactaatg
    10861 atgacaaaaa ggggtctatg caatgcagcg caaagtaacc atcaatgata ttgctgactt
    10921 agctaaaact tcaaaaacaa ctgtttcttt ctacctcaac ggtcgatttg ataaaatgtc
    10981 tcaggagaca aaaagccgga tcaaggaggc tattgaagcc accaactaca agcctagcat
    11041 tgcagctcgc agtctcaatg ccaaggctac caaattgatc ggtgtggtta tcggtgacat
    11101 caccaatagc ttttccaacc agattgtcaa aggtattgaa agcaaggcgc aagaatttgg
    11161 ttatcagatt atcatcggca acagcaacta tgatccttca cgtgaggacg aattgattga
    11221 aaaaatgctt aacctaggtg tagatggttt tatcattcaa ccaacctcta actttagaaa
    11281 gtattcacgc atcatcgaag tgaaaaaaaa gcgcatggtt ttctttgaca gtcagctcta
    11341 tgagcatcgt acaaactggg tcaagaccaa caattatgac gctgtttatg acaccattca
    11401 gcaatgcatc accaaaggct atcaaagctt tatcatggtt actggcaatc ctaatttgct
    11461 gagcacacgc atcgagcgtg cctctggttt tattgatgtt ttagaggcta accagctcca
    11521 gtatcgtcaa atgatcatcg atgaaaacca aaccagctct caagaaattg ctcagtttct
    11581 acaaggcgca tttgataagg aacgtcacaa tctggtattt gtcccaaact gctgggctct
    11641 gcctaaggtt tttactgcca tgaaggcact aaaggtatca ttgcccgaaa ctggtctagt
    11701 tggctttgat aacatcgaat ggactcgctt gtcatcacca agtattacca ctattatcca
    11761 gcctgcttac gaagaagggg agcaagcaac cagcattttg attgatgata tcgaagggca
    11821 tagcaaggaa gccaagcaac aaatttttga ttgtcaggtt aattggcaag aatcaacctt
    11881 ctaacaggat tttttcgcct tctagacctt aaaaaatcag ccattctaat aacgatgaca
    11941 aagtaacacg aggcttaacg cttgtttgct agcatcagaa aaaacacata aatcagcctg
    12001 aactacccgg ttgatgaaac aataaaccat taagcaacgg tcttattcct cataccaaga
    12061 ggagcaaggc cgttttgacg tttttgacaa tggtcgttat tgtaaacgta acggtagtgt
    12121 attactgaca ggctcttcaa aaaagctgtc gtccttaggt catacgaggc cttcttttac
    12181 aagcgactgc tacttcttca ctactagtgt gatcttttag ccaatttctg agaacatcat
    12241 cagtaaaatc tcgcacctgc caataatggc aagcaagctt ttttgaccag caagttaatc
    12301 atgtatcact tgtgacttca actcttaact gtttgtcctt tcaagtctac tataagag
//
LOCUS       DARYXW010000060        12332 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.060, whole genome shotgun sequence.
ACCESSION   DARYXW010000060 DARYXW010000000
VERSION     DARYXW010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12332)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12332)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12332
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.060"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(153..962)
                     /locus_tag="TV191_001364"
     CDS             complement(153..962)
                     /locus_tag="TV191_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEL1507870.1"
                     /translation="MDKLILGRYIPGNSIIHRLDPRSKLLAMIIYIIIIFWANNVVTN
                     LLLLAFTLLLIFLSQIKWSFFFNGVKPMIGIILFTTLFQVFFTQGGSVLFQLGIIKIT
                     SLGLSQAILIFMRFVLIIFFSTLLTLTTTPLSLSDAVEALLKPLVRFKVPAHEIGLML
                     SLSLRFVPTLMDDTTRIMNAQKARGVDFGEGNLIQKVKSIIPILIPLFASSFKRADAL
                     AIAMEARGYQGGDSRTKYRLLSWQLKDTLAIILVVILGIFLFCLKSPSRLT"
     gene            complement(955..1797)
                     /locus_tag="TV191_001365"
     CDS             complement(955..1797)
                     /locus_tag="TV191_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEL1507871.1"
                     /translation="MSIHFQNVSYTYQAGTPFEGRALFDVNLDIVDGSYTAFIGHTGS
                     GKSTIMQLLNGLHLPTTGKVTVAGKEITSQSKNKDIKPIRKQVGLVFQFPESQLFEET
                     VLKDVAFGPQNFGVSQKEAEALAREKLTLVGISEELFGKNPFELSGGQMRRVAIAGIL
                     AMQPDILVLDEPTAGLDPKGRKELMSLFKSLHQSGMTIVLVTHLMDDVANYADFVYVL
                     EAGKIILSGQPKAIFQHIDLLKEKQLGVPKVTAFAQRLAKQGFDLPYLPITLEELREV
                     LKHG"
     gene            complement(1773..2612)
                     /locus_tag="TV191_001366"
     CDS             complement(1773..2612)
                     /locus_tag="TV191_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEL1507872.1"
                     /translation="MSNIIEVKNLTFKYKQDQERYTLDDVTFHVKQGEWLSIIGHNGS
                     GKSTVVRLIDGLLKAEAGQIFVDGDLLTEDNVWDIRHKIGMVFQNPDNQFVGATVEDD
                     VAFGLENKGVSHQEMIERVHQALQLVGMEAFKDKEPSRLSGGQKQRVAIAGAVAMRPM
                     IIILDEATSMLDPKGRLELIRTIQSIRQEYQLTVISITHDLDEVALSDRALVMNNGRV
                     ESVSTPQELFARGNQLINLGLDIPFTTSVVNMLKKDGYPIQGIYLTEKELEEQLCQFI
                     SKM"
     gene            complement(2615..3157)
                     /gene="pgsA"
                     /locus_tag="TV191_001367"
     CDS             complement(2615..3157)
                     /gene="pgsA"
                     /locus_tag="TV191_001367"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003090075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEL1507873.1"
                     /translation="MIKKENIPNLLTLARIVMIPLFLLITSFSKTVGWHTFAAIIFAV
                     ASLTDYLDGYLARKWQVVTNFGKFADPLADKMLVMSAFIMLVGLELVPAWVSAVIICR
                     ELAVTGLRLLLVETGDKVLAAAMPGKIKTVAQMLSIIFLLCHWTVLGTVLLYIALLFT
                     IYSGYDYFKGASFLFKDTFK"
     gene            complement(3170..4174)
                     /locus_tag="TV191_001368"
     CDS             complement(3170..4174)
                     /locus_tag="TV191_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1507874.1"
                     /translation="MRETSLGELLRETRVGKNITLDEIEAKTGISSHYLLAMELDQFK
                     IIPEEKFGHFLKQYADIVGLDFDSLKRLYQLQVSFKKETGTPSVTQIVEEKLSKKRLQ
                     ENSYSEKIAQPEPSRTQPETLVIPVKTSLSSSKSAPTASHFKATDHRRTRETSASRLS
                     RYGNSAKTKKSAFPSALLGLIAVAIVGVIGFAVWKQFDKGQKAKEAEMSFLKSSQSSH
                     STASSSSEPKTVITTEGAENYLIANITKSKEAVDVTVSLTDAESSWISLTNSEIGEAG
                     MTLTKDNPTYSTTLPAETTESLLTLGVTKGVSVAIDGQPLDLSAMTSTDISYITLKIQ
                     "
     gene            complement(4224..5507)
                     /locus_tag="TV191_001369"
     CDS             complement(4224..5507)
                     /locus_tag="TV191_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEL1507875.1"
                     /translation="MTSLLKKDYPSIKETLHYGQLANGLRVYLIKKEGYSEKTAMLTA
                     RFGSLDTSFTVNCQRFDLPSGVAHFLEHKLFEDKDGNDIALTFTQLGSETNAFTTFDK
                     TSYFFSTVNEWQESLRLLQEFVAAPSFTEESVNREKHIITQEIEMYQDDPDYQAYSGI
                     LQNLFPNTSLAVDIAGTKESIRDITGSLLADSHAYFYHPSNMVLTIIGDIDIEEAFTA
                     IEAFQDSQPSQTQYDVQIAPLTYYPVIKSRSIDMDVATAKLAVGFRGQLMSSEYSLLT
                     YQVALRLLLAVLLGWTSKTYQDWYEKGKIDDSFDIEVDIQRDFQFVLISSDTSQPIAM
                     SNSIRKKISDFRCSRDVNEEHLELVKKEMYGDFMQSLDAIDQLASQFSLHLSEQETYF
                     DIPRIIETLALKDIIEIGSLFFEHAATSDFTVFPK"
     gene            complement(5509..6753)
                     /locus_tag="TV191_001370"
     CDS             complement(5509..6753)
                     /locus_tag="TV191_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEL1507876.1"
                     /translation="MKLIQGVQLHLIKNKTFKTNQITFRFSGDLNQKTVAKRVLVAQM
                     LATANDTYPTAKQFREKLAQMYGASLSTHVSTKGLVHIVDIDITFIQDQYAFYGEKLL
                     DEMIQFLKDILFSPLLSVAQYQPKLFDIEKRHLMTYVEADKEDSFYYSALKAKQLFYA
                     NDSLKLSKYGNTELIAKETAYTSYQEFHKMLNEDQIDIFILGDFDDYRMVQLLHQFPF
                     EGRRKKLDFFYLQQPVNVVNELVEQKQLNQSVLELAYHFPLVYGQAEYYALVVLNGLL
                     GAFTHSRFFTQIREKEGLAYSIGSRFDVYTGLFEAYAGIDRQHRTRALQLMVKELNDI
                     KMGRFSSSLVKKTKLMLKNNALLSEDNSKALIELEYMRSYIDPSYTLSSWLDEIDKVS
                     KLDIVRTANLLKLQAVYFLEGK"
     gene            6968..7381
                     /gene="yaaA"
                     /locus_tag="TV191_001371"
     CDS             6968..7381
                     /gene="yaaA"
                     /locus_tag="TV191_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEL1507877.1"
                     /translation="MTYTLFTDFITLQALLKEQGIIQSGGAIKGFLAQTEVFLNGQEE
                     QRRGKKLRVGDVITIPSQHIKIELVAPSQAEKTAYEAEKAEKERVAKMVKQMNQQAKK
                     AQTKQAATTKSKRGQATSAVKAKSNHQKPIRFPGL"
     gene            7383..8492
                     /gene="recF"
                     /locus_tag="TV191_001372"
     CDS             7383..8492
                     /gene="recF"
                     /locus_tag="TV191_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEL1507878.1"
                     /translation="MWIKELNLTHYRNYQQASAAFSPGLNVFIGDNAQGKTNFLEAIY
                     FLSVTRSHRTKSDKDLIYFDERDCSISGTLERLSGRVQLEILLSDKGRITKINTLKQA
                     KLSDYIGAMMVVLFAPEDLQLVKGSPNLRRKFMDIDLGQIKPVYLSDLSHYNHVLKQR
                     NAYLKSVHQLDNDFLSVLDEQLVTYGSRVMAHRLAFVQSLAKEANKHHQAISNGLEKL
                     SISYQASVSFEHQQEIYQQFMNQLKTTHQRDFLRKNTGVGPHRDDLVFYINDMNANFA
                     SQGQHRSLILSLKMAEVSLMKQLTGDNPILLLDDVMSELDNTRQTKLLGAVKKENVQT
                     FITTTSLEHLSQLPKDISLFKVNKGTIERDSIMID"
     gene            complement(8557..9420)
                     /locus_tag="TV191_001373"
     CDS             complement(8557..9420)
                     /locus_tag="TV191_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HEL1507879.1"
                     /translation="MEGILFALVPMFAWGSIGFVSNKIGGKPSQQTFGMTIGALLFAL
                     VVWLVVRPEMSMKLWIFGILGGIIWSVGQTGQFHAMQYMGVSVANPLSSGSQLVLGSL
                     IGVLVFHEWTKPIQFVVGTIALLLLIVGFYFSSKQDETNAASNQLHDFSKGFRALTYS
                     TTGYVMYAVLFNNIMKFDVLSVILPMAVGMVLGAAMFMSFKVSFDQYVIKNSVVGLLW
                     GVGNIFMLLAASKAGLAIAFSFSQLGAIISIVGGILFLGETKTKKEMRWVITGILCFI
                     VGAILLGIVKS"
     gene            complement(9591..12020)
                     /locus_tag="TV191_001374"
     CDS             complement(9591..12020)
                     /locus_tag="TV191_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEL1507880.1"
                     /translation="MMILTDEQRQRIAEEEYEKHTVGSPVLIDDDNSEFSIGYVSQIE
                     DSISGFQAYVVTDVKLPPHPTKADYAQVKHVTMLYRGSTGPDQWQKHPVDVVADWVGN
                     DLPMAMRILLPDQTPTKGTAQLRKAATFTNKTLKQYPNATFEFYGHSLGSMTVQYGVT
                     SVSDKNLSRISGVYIYNGPNTYRVLNEYQRKRAKLLHDRIYNYVDPHDIIGMGFDQKE
                     GAVGQVFVVNTKKVNDIVLQHMWHGYQYDQYGNMTDVNGRFVHANVLLPIDIDSDNRL
                     DTKVEELYLGFRNYFDSSTSARYGVLSDKQTIVINAGVLTNLAQNLQSSISGDLQTIR
                     HITEKCQAKNDAIKDSFEERKKRVSENIKALLATNGLTDTFNSLQSSLERLVGQQDLF
                     DMLSHSASLDYPFSYDEIPYVNNNRLNLAMYDSELASLNTKSLQLASSAQHEKSGWID
                     SIIGRSTLLKSWQIIDEASRQLLKESDKTFEGTGLRESKVDGISDSLKEVFSVELQDI
                     IELEKMIINTSELILGVSQNVTATDNWLGNSLKNGQFQGSADVVCVPSSYDAYLERTG
                     LLDDVRDILQAFDEQVEQKSRDYSRKVASVYASTFSRLFDTLDYWTTEVNIFKNIVTV
                     LERRFSDRVYVERTEIKDETSTTTRSYWGNLGALYPCRIRSGIASARAEVCPLVPALT
                     DTIQRVNTARHRLQNLHGDLSRLIEKGVYSALDLDDIITSQKMVGRLLDKIIVELSFV
                     KATIEASMSGQAASAMVNHLALLLKRLGYFSQLVADCFGTQVTKVPNKAPARASHKVK
                     RFSLNNPLALQ"
BASE COUNT         3805 a         2642 c         2305 g         3580 t
ORIGIN      
        1 ttttctagcc tgatatcagt gttttttgag cttaagaagc tcaaaataaa aacaatgcct
       61 aagttcagac ctgtgtaaca gatgatttaa gcattgttat tattaataaa ttctagttgc
      121 tacagcctaa caaaggggct gctgtaatat agctaggtga gccttgaggg actttttaga
      181 cagaaaagga aaatccccaa aatgactacc aaaataatgg ctagagtgtc ttttaattgc
      241 cagcttagca ggcggtattt tgttcgactg tcaccgcctt gatagcctct agcctccata
      301 gcgatcgcta aagcgtcagc tcttttaaag cttgaagcaa aaagaggaat caaaataggg
      361 ataatcgact ttaccttttg aataagattg ccttctccaa aatcaacacc tcgcgctttt
      421 tgcgcattca taatacgagt tgtatcgtcc atcaaggttg gaacaaaccg taagctcaaa
      481 gataacatca aaccgatctc atgggcaggt accttaaacc taactaaagg cttcaacagc
      541 gcttcaacag catcagataa gcttagtggg gtggtggtta gggttaacag cgtggaaaag
      601 aaaataatca aaacaaatcg catgaaaatc aaaatggctt gacttaatcc caagcttgtt
      661 atcttaatta ttccaagctg aaaaagaact gatcctccct gtgtaaaaaa aacttgaaaa
      721 agcgttgtaa ataggataat accaatcata ggcttaacac cattgaaaaa gaaagaccat
      781 tttatctgtg acaagaaaat cagcagcaag gtaaatgcta acagcaaaag attagttacc
      841 acattattgg cccaaaaaat aatgataata tagataatca tagcaagcag cttgcttctt
      901 ggatcaagcc gatgaataat tgaattccca ggaatatagc gaccaagaat gagtttatcc
      961 atgctttaat acctctctta attcctccaa agtaatgggt aaatagggta aatcaaagcc
     1021 ttgcttagcc aggcgttggg caaaggctgt caccttaggg acacctaatt gtttttcttt
     1081 tagcaaatca atgtgttgaa aaatagcctt tggctgacct gataagatga ttttaccagc
     1141 ttcaaggaca taaacaaaat cagcataatt agcaacatcg tccatcagat gtgtcaccag
     1201 tacaatggtc atgcctgatt gatggagcga tttaaaaaga ctcattaatt cctttcgccc
     1261 tttgggatca agcccagcag taggctcatc taacaccaaa atatccggct gcatcgcaag
     1321 aatacccgca atagcaaccc tgcgcatctg cccaccagaa agctcaaatg gatttttacc
     1381 aaatagttcc tctgaaatcc ctactagggt taatttttca cgcgctaaag cttccgcctc
     1441 tttctgagaa acaccaaaat tttgtggtcc aaaggcaaca tccttcaaaa ccgtttcctc
     1501 aaaaagctgg ctctcaggaa attgaaagac tagaccaacc tgcttacgaa taggcttaat
     1561 atctttattt tttgactgac tagttatctc cttgcctgct accgtaacct tgccggtggt
     1621 cggcagatgc aagccattta agagctgcat aatcgttgac ttgcctgagc cagtatgacc
     1681 aataaaagcc gtataagagc cgtctacaat atcaagatta acgtcaaaaa gggcacgccc
     1741 ctcaaagggt gtccctgctt gatacgtgta gcttacattt tggaaatgaa ttgacatagc
     1801 tgttcctcta attccttttc tgtgagatag attccctgta tagggtagcc gtcttttttt
     1861 agcatattaa caacagaggt tgtaaaagga atatctaaac ctagattgat caattgattg
     1921 cccctagcaa atagctcctg tggagtcgag acagactcaa cacgcccatt gttcatcacc
     1981 aaagctcgat cactaagagc cacctcatca agatcatgtg taatagatat aacagttagt
     2041 tggtattctt gtctaataga ttgaattgtc cgaatcaact ccagacgccc ctttggatcc
     2101 agcatactgg ttgcttcatc taaaatgatg atcattggcc gcatggcaac agcacctgca
     2161 atagcaaccc gctgcttttg accacctgat aatctggaag gctccttatc cttaaaagcc
     2221 tccataccga ccagctgcaa cgcctgatga acacgctcta tcatctcctg atgggaaaca
     2281 cctttgtttt caagaccaaa agcaacgtca tcttcgacag ttgcaccaac aaattggtta
     2341 tcaggatttt gaaataccat gccaatttta tgacgaatgt cccagacatt gtcctctgta
     2401 agaagatcac catcaacaaa aatctggccg gcttctgctt tcaatagccc atcaattaac
     2461 ctaacaacgg ttgacttgcc tgagccatta tgcccaatga tagacaacca ctcgccttgt
     2521 ttcacatgaa acgtcacatc atctagggta tatcgctcct ggtcctgctt atacttaaat
     2581 gtaagattct taacttcaat aatatttgac attgttattt aaaggtatcc ttaaaaagaa
     2641 agcttgctcc tttgaaataa tcgtaacctg aataaatcgt aaacaataga gcaatataca
     2701 gcaaaacagt gcctaaaaca gtccaatgac acagtaaaaa gatgatggaa agcatctgtg
     2761 ctactgtttt gatcttacca ggcatagcag ctgctaggac cttatctcca gtctcaacca
     2821 atagcaaacg aagtcctgta acagctagct cacgacagat aataaccgct gacacccaag
     2881 ccggtaccag ctctaagccc actaacataa taaaagcact catgacaagc atcttgtctg
     2941 ccaatggatc agcaaattta ccaaaattag taacaacctg ccacttacgt gcaaggtaac
     3001 catctaaata atcggtcagg cttgccactg caaaaataat cgctgcaaag gtatgccaac
     3061 cgactgtctt tgaaaaagag gtgatcaaca aaaacaatgg aatcatgacg atacgggcga
     3121 gagttaacaa attgggaata ttttcttttt tgatcatgct tataccttat tattgtatct
     3181 tcagtgtgat atagctgata tcagtacttg tcattgctga taaatctagg ggctgaccat
     3241 caattgctac tgaaacaccc tttgttacgc ctagtgtcaa caaggattct gttgtctcag
     3301 caggcaaggt agtagaataa gtcggattgt cctttgttag ggtcatacca gcctcaccaa
     3361 tttccgaatt agtgagggaa atccaactgc tctcagcatc agtcagtgac actgtaacat
     3421 caacagcttc ttttgattta gtaatattag caatcaagta attctctgcg ccctctgttg
     3481 tgatcaccgt cttaggctca gatgagctgg acgctgttga gtgactgctt tgtgatgact
     3541 taagaaaaga catctcagcc tcttttgctt tttgaccttt atcaaattgc ttccaaacag
     3601 caaaaccaat aacaccaaca atagccacag caataagacc tagtaaggct gatggaaagg
     3661 ctgatttttt cgttttagca ctatttccat aacgacttag ccttgaagca ctggtctctc
     3721 tagtccgtct atggtcagta gccttaaagt gactagctgt aggagctgat ttgcttgagg
     3781 atagtgacgt cttgacagga atcactaggg tttctggttg agtccttgaa ggctctggtt
     3841 gagctatttt ttcagaatag ctattctctt gtagcctttt tttgctgagc ttttcttcaa
     3901 cgatttgtgt gactgatggt gtacctgttt cctttttaaa gctcacctgc agctgataca
     3961 agcgttttaa gctatcaaag tctaagccaa caatatcagc atattgcttt agaaaatgac
     4021 caaacttttc ttctggaatg attttgaact ggtcaagctc cattgccaat agataatgcg
     4081 aggaaatgcc agttttagct tcaatttcgt ctaatgttat gttttttccg acacgtgttt
     4141 ctcttaataa ttcaccgaga cttgtttctc tcatacgagt acctcaaaaa tattgtaata
     4201 agaccattat aacagatttt aagctatttg ggaaagactg taaaatctga agtagctgca
     4261 tgctcaaaaa acaagcttcc tatttcgata atatccttta aagctagggt ctcaataatc
     4321 ctaggaatat caaaataggt ctcttgctct gataaatgaa ggctaaattg gcttgccagc
     4381 tgatcaatag cgtctaagct ttgcataaaa tccccataca tttccttttt cactagctct
     4441 aagtgctcct cattaacgtc tcttgagcat ctaaaatcgg aaatcttttt tctaatgctg
     4501 ttagacattg caataggctg actagtatct gaagaaatca atacaaattg gaaatccctt
     4561 tgaatgtcaa cctctatatc aaaggagtcg tctatcttgc ccttttcata ccaatcctga
     4621 taggtttttg acgtccagcc aaggagcacc gctaggagca gtctaagagc tacctgatag
     4681 gtgagtagag aatactcgct tgacattagc tgaccgcgaa agccgactgc taatttggca
     4741 gtcgcaacgt ccatatcaat agatctagac ttgatcacag ggtagtaggt caatggagct
     4801 atctgtacat catactgcgt ctgacttggt tgactatctt gaaaggcttc aatagctgta
     4861 aaggcttctt caatgtcaat atcgccaata atcgttaaga ccatgttaga agggtgataa
     4921 aaataagcat ggctgtcagc caataaagag cctgtaatgt ccctgataga ctccttggtc
     4981 ccagcaatat caacagctaa gctggtattg ggaaagaggt tctgtaagat accactgtaa
     5041 gcctgataat caggatcgtc ctgatacatc tcaatttctt gagtgataat atgtttttca
     5101 cgattaaccg actcctctgt aaagctagga gctgctacaa attcctgcaa aagtctcaga
     5161 ctttcttgcc attcattgac agttgaaaag aaatagctcg ttttatcaaa ggttgtaaag
     5221 gcatttgttt ctgatcctaa ctgtgtaaat gtaagagcaa tatcattacc atctttatcc
     5281 tcaaatagct tgtgctctaa gaaatgagca acacctgacg gcaagtcaaa cctttgacaa
     5341 ttgactgtaa agcttgtgtc aagagaacca aaacgagcag tcagcatagc tgttttctca
     5401 gaatagccct ctttctttat caaataaacc cttaaaccat ttgccaattg accgtagtgt
     5461 aaggtctctt taatgctggg atagtctttt ttcagtagtg acgtcatctt attttccctc
     5521 taaaaaatat acagcttgca gcttgagtag attagctgtc ctgacaatat ctagcttgct
     5581 aaccttgtca atctcgtcaa gccaacttga caaagtatag gaaggatcta tataagatct
     5641 catgtattcc agctcaatca aggctttact attatcctca gatagcaagg cgttattttt
     5701 tagcattagc tttgttttct tgacaaggct gcttgaaaag cgccccatct tgatgtcatt
     5761 gagctcttta accattagct gcagggctct tgtccggtgc tgtctatcta tgccagcata
     5821 agcctcaaat aagcctgtgt aaacatcaaa tcgactacca atactatagg ccagcccctc
     5881 cttctcacga atttgggtaa agaagcgaga gtgtgtaaag gctcctaata gaccatttaa
     5941 cacaactaag gcataatact ctgcttgccc ataaaccagc ggaaaatgat aggctagctc
     6001 taaaacagac tgattaagct gcttttgctc gaccaattcg ttgacaacat tgacaggctg
     6061 ctgtaaataa aagaaatcta gctttttcct gcgtccctca aagggaaatt ggtgtaacaa
     6121 ttgtaccata cgataatcat caaaatcacc aagaataaaa atatcaatct gatcctcatt
     6181 caacatttta tgaaattctt gatagcttgt gtaggctgtt tctttagcaa ttaactcagt
     6241 attaccatat tttgacagct tcaggctatc attagcataa aataattgct tggcttttag
     6301 ggcactataa taaaaggaat cctccttatc tgcctcgaca taggtcatca aatgtctttt
     6361 ttcgatgtca aatagtttgg gctggtactg agccactgat aacaaaggag aaaaaaggat
     6421 atcctttaga aattgaatca tttcgtctag aagcttctct ccataaaaag catactgatc
     6481 ctgaataaag gtaatgtcaa tatccacaat atgaaccaaa cccttggttg acacatgagt
     6541 tgacaggctt gctccataca tttgtgctaa tttttctcta aattgcttgg cagtaggata
     6601 ggtatcgtta gccgttgcta acatttgagc tactaagact cgctttgcta ccgttttttg
     6661 attcaaatca cctgaaaagc gaaacgttat ctgattcgtt ttaaatgttt tgttttttat
     6721 cagatgaagc tgaactccct gaataagttt cataatattt ccttattaat aaatgtgtga
     6781 tctctagaat tataccattt ttatcgctat tcgttgagtg ttaacatcag tctggtagcc
     6841 tattttgact ctttatcaaa atgctatcct gtggctatag tctagacttt agaaggtcag
     6901 catttcagca ttattattta gtggcttttt atgctataat gacttgaatg acaaattgga
     6961 gatgactatg acatacacac tatttactga ctttattacc ctacaagctt tattaaagga
     7021 gcaaggtatt atccaaagtg gtggtgccat taaaggtttt ttagctcaaa cagaggtttt
     7081 tttaaatggt caagaggaac aacgacgtgg caagaagcta agagtcggtg acgtcatcac
     7141 cattccatca cagcacatca agattgagct tgtagcgcct agtcaggccg aaaaaacagc
     7201 ctatgaagct gaaaaggcag aaaaagagcg agttgctaag atggttaaac aaatgaatca
     7261 acaggctaaa aaagcacaga ccaagcaagc agctactacc aaaagcaagc gtggtcaagc
     7321 tacctcagct gtaaaagcta agtctaatca ccaaaagcct attcgcttcc caggattgta
     7381 gcatgtggat caaagaacta aacctcaccc attaccgtaa ttatcaacaa gcctcagcag
     7441 ccttttcacc gggcttgaat gttttcattg gtgacaatgc gcagggcaag acaaattttc
     7501 ttgaagctat ttattttttg tcagtaacaa gaagtcatcg caccaaatct gataaggact
     7561 taatctactt tgacgaaagg gattgctcta tatctggaac tcttgagcgc cttagtggtc
     7621 gtgttcagct agaaatactg ctgtctgata agggacggat caccaagatt aacaccctaa
     7681 agcaagcaaa gctttctgat tatatcggag caatgatggt ggtcctcttt gctcctgagg
     7741 atctacagct ggtcaaaggc tctcctaatc ttagacgaaa atttatggac attgacttag
     7801 gtcagataaa gcctgtttac ttatcagatt tgtcacatta caatcatgtc ctaaagcagc
     7861 gaaatgccta tctcaaaagt gttcatcagc ttgataatga ctttttatct gtgttagatg
     7921 agcagctggt tacctacggg agtcgtgtaa tggcgcatcg gttggcgttt gttcaatcac
     7981 tagcaaaaga ggcaaacaag catcatcaag ctatctctaa tggcctagag aagctttcga
     8041 tctcctatca agcctctgtg agctttgagc accagcaaga gatttatcag caattcatga
     8101 accagctcaa aaccactcat caaagagatt tcttgagaaa aaatactggt gttggccccc
     8161 accgcgatga tctggttttt tatattaatg acatgaacgc taattttgct agtcaaggcc
     8221 agcatcgtag cctgatttta tcactgaaaa tggcagaggt tagtctgatg aagcaattaa
     8281 caggtgacaa ccctattctt ctacttgatg atgttatgag tgagttagac aataccagac
     8341 aaacaaagct tctgggagct gtcaagaaag aaaatgttca aacctttatc acaacaacta
     8401 gcttagagca tttgtctcag ctacctaagg acattagtct ctttaaggtt aataaaggaa
     8461 caatagaacg agattctatc atgattgatt aactgagcaa actaaaaaaa gggcacctta
     8521 atagtgaccc tttttacggt taaattagtt gatactctat gatttgacga tacctaagag
     8581 gatagcgcca acaataaagc aaaggatacc tgtaatgacc cagcgcatct cttttttggt
     8641 ttttgtctca cctaagaata aaatacctcc gacaatagag ataatagcgc ccaattgtga
     8701 aaagctaaaa gcaatcgcca gaccagcctt tgaggctgct agcagcatga agatatttcc
     8761 aactccccaa agcaagccaa caacactatt tttgataaca tactggtcaa acgatacctt
     8821 aaacgacata aacatggctg caccaagcac cattcccact gccatcggta aaataaccga
     8881 caacacatca aatttcataa tgttattgaa cagcacagca tacatcacat agccggttgt
     8941 cgagtaggtt aaggctctaa agccctttga aaaatcatgc aattgattac ttgctgcatt
     9001 cgtctcgtcc tgcttgcttg aaaaataaaa accaacaatc aaaagaagta aggcaatcgt
     9061 accaacgaca aattgaatag gcttggtcca ctcatgaaag accagcacac caatcaggct
     9121 acctaaaact agctgagaac cactagacaa gggatttgct actgaaacac ccatatactg
     9181 catggcatga aattgcccag tctgaccaac agaccagata ataccaccta aaatcccaaa
     9241 aatccagagc ttcatagaca tctcaggtct gactactaac caaacaacta gagcaaatag
     9301 taaagctcct atggtcattc caaaggtctg ctgtgagggt ttaccgccaa ttttattact
     9361 aacaaagcca atacttcccc atgcaaacat tgggacaagt gcaaataaaa taccttccaa
     9421 atttacatct cctttacaat aagttgacac atgatgttaa cgataaaagt gctttcatac
     9481 ggagaattat tatagcctat ttccttagaa aatacaataa catgatgtaa aaaatcatct
     9541 gctcacacgc ttctccctaa aaaggtgtca aagtagctga cagagcttat ttactgcaat
     9601 gctagaggat tatttaatga aaaccgtttg accttatggc tggctctagc tggagctttg
     9661 ttagggactt ttgtgacctg agttccaaag caatcagcaa ctagctgact gaaatagcct
     9721 aagcgtttga ggagtagagc aagatgatta accatagcac tagctgcttg accggacatg
     9781 cttgcttcta tggtagcttt gacaaaggat agctcaacga tgattttatc cagcagtctg
     9841 ccaaccatct tttgactagt gatgatgtca tctaaatcaa gagcgctgta aactcctttt
     9901 tcgatcaatc gactgagatc tccatgcaag ttttgaagcc gatgccttgc ggtattgact
     9961 cgctgtatcg tatcagtcaa tgccggtact agaggacata cctcagctct ggcagaagca
    10021 ataccggatc ttatgcggca aggatataaa gcacccagat ttccccaata gctccttgtc
    10081 gttgtagagg tttcatcttt gatttctgtt cgttcaacat aaaccctatc tgaaaaacgt
    10141 ctctctaata ctgtcacgat attcttaaag atattcacct cagtagtcca ataatcaagt
    10201 gtatcaaata gccttgaaaa ggttgacgca taaacagagg caacctttct ggaatagtcc
    10261 cgactctttt gttccacctg ctcatcaaag gcttggagaa tatctctgac atcatctaaa
    10321 agacctgttc tttctaggta agcatcatag ctgcttggga cacagacgac atcagcactt
    10381 ccttgaaatt gaccattttt taggctgttg cctagccagt tatctgtagc tgtgacattt
    10441 tgtgataccc ctaggatcag ctcactggta ttgattatca ttttttccag ctctatgata
    10501 tcctgtaatt ccacgctaaa tacctctttt aaggaatcgc taataccgtc aactttactt
    10561 tcacgtaaac ccgttccttc aaaggtctta tcactctcct tcaatagctg acgactggcc
    10621 tcatcaataa tctgccaaga tttcaaaagt gtcgagcgac cgataatact atcaatccag
    10681 cctgactttt catgctgagc agatgaggca agctgaagcg attttgtgtt taagctcgct
    10741 aattctgaat catacatggc cagattgagg cgattattat tcacatatgg gatctcatca
    10801 taggaaaagg gatagtctag gctagccgaa tgagacagca tatcaaacaa gtcctgctga
    10861 ccaactaatc tctccaaaga actttgcagg ctattaaaag tatcggttag gccatttgta
    10921 gcaagcaggg ctttgatgtt ttctgaaact cgctttttcc tctcttcaaa ggagtctttt
    10981 atggcatcat tttttgcctg acatttttca gtaatgtggc gaatcgtttg caggtcgcct
    11041 gatatagagg attgaaggtt ttgtgcaagg ttagtcagga caccagcatt gatgacaatc
    11101 gtttgcttat cagaaagcac accgtaccga gccgatgttg acgaatcaaa gtaatttcta
    11161 aagcctaagt acagctcctc taccttagtg tctaatcggt tatcgctgtc aatatcaata
    11221 ggcaacagga cattagcatg aacaaaccgg ccatttacgt ctgtcatgtt gccatattga
    11281 tcatactgat agccatgcca catatgctgt aagactatat cattgacctt ttttgtattg
    11341 acaacaaaga cctgaccgac tgctccctcc ttttggtcaa agcccatacc aatgatgtca
    11401 tgcggatcca catagttgta aatgcggtca tgcaagagct ttgcacgttt tctttgatac
    11461 tcattaagca cacgataggt gttggggcca ttgtagatat agactccaga gatacgagat
    11521 aagtttttat cactaacaga ggtaacaccg tactgaactg tcatggagcc tagcgaatga
    11581 ccataaaact caaatgttgc gttagggtat tgctttaatg tcttattggt aaaggttgct
    11641 gcctttcgga gctgagctgt ccctttagtt ggtgtctggt ccggtaaaag aatgcgcata
    11701 gccataggca aatcattgcc tacccaatct gcaaccacat ctactgggtg tttctgccac
    11761 tggtctgggc cagtagagcc ccggtacagc atggtgacat gcttgacctg agcatagtct
    11821 gccttggtag gatgaggggg aagcttgaca tctgtcacga cataggcttg aaaacctgat
    11881 atcgaatcct ctatctgaga cacataaccg atggaaaact cagaattatc atcatcaatt
    11941 aaaactggtg aacctactgt atgtttttca tactcttcct cagcaatccg ttgtctctgt
    12001 tcgtctgtca ggatcatcat tttcactctc cttttagtag tttttctaac ttttctgagc
    12061 gataattact agcgatctct aaatttcttt ctaaatcata tctactaagg cgaaccctta
    12121 aataagtatc tggatcatca ttgataatca ggtgaataga aaaacctccc ctggcttgaa
    12181 tgaactgtga actgcccccc aaaagttaga cataaaatct aacaattggg gggctatttt
    12241 tatgacattg agttatgaag acaaggttca aatctatgag ctacggcaca ttggaaagtc
    12301 cattaaatgc ttatcagaaa agtttagtat tg
//
LOCUS       DARYXW010000061        12179 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.061, whole genome shotgun sequence.
ACCESSION   DARYXW010000061 DARYXW010000000
VERSION     DARYXW010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12179)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12179)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12179
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.061"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            32..550
                     /locus_tag="TV191_001375"
     CDS             32..550
                     /locus_tag="TV191_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1507881.1"
                     /translation="MTNNIAKLIEESGKKIKSISEALDISYPTLSSYNQGIRKPKKEN
                     AQKLADYFGVSVAYILGIDEEKYAPSNLKIVTDSFKTSEITSVTPFKSDMEKLKKGIE
                     LGEIHLSMPLNEVFSDDFRRILSNYLMDYEETFIKDLIKFMNNQGQKSDIWKTWIQTE
                     EFQIRRADRDRK"
     gene            604..1695
                     /locus_tag="TV191_001376"
                     /pseudo
     CDS             604..1695
                     /locus_tag="TV191_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378871.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(1810..2202)
                     /gene="rpsI"
                     /locus_tag="TV191_001377"
     CDS             complement(1810..2202)
                     /gene="rpsI"
                     /locus_tag="TV191_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEL1507882.1"
                     /translation="MAQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTEGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(2222..2668)
                     /gene="rplM"
                     /locus_tag="TV191_001378"
     CDS             complement(2222..2668)
                     /gene="rplM"
                     /locus_tag="TV191_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEL1507883.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKVYYTHSMYPGGLKSITAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGGEHTHAAQQPEVLDISGLI"
     gene            complement(3207..4067)
                     /locus_tag="TV191_001379"
     CDS             complement(3207..4067)
                     /locus_tag="TV191_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL1507884.1"
                     /translation="MTFVLMTDSTADLDSFWAKEHNIDIVGLTVECDGKVYKTVGPDR
                     LTSDALLAMMKSGSQPKTSQINVGQFEEIFRHYAADNQALLYIAFSSVLSGTYQSAVM
                     ARELVLEDYPDAVIEIVDSLAAAGGEGYLTMLASEARDNGKSLLETKAIIEGILPRLR
                     TYFLVDDLFHLVRGGRLSKGSAFIGSLVNIKPLLWIDASGKLVPIAKIRGRKKAIKEI
                     ADRATKDIADSTVVVSYTSDQTGADDLREQLLAHEGISDVFMLPLGPVIAAHTGPDTL
                     AVFVIGKEKR"
     gene            complement(4251..4769)
                     /locus_tag="TV191_001380"
     CDS             complement(4251..4769)
                     /locus_tag="TV191_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HEL1507885.1"
                     /translation="MKKRLLLVDGYNMIAFWESTRQFFKTNQLDQARRILLNKLNNYA
                     HFDDSDIICVFDAQYVPGLRQRYDQYRISVIFTEEEETADSYIERTAAELNTALTMVE
                     VATSDLNEQWTIFSQGALRVTAKELEQRVNAVKSDLDKLSQDIDLKKPRLGPFDQGQL
                     NQLKDFMNRLDD"
     gene            complement(4770..5516)
                     /gene="rlmB"
                     /locus_tag="TV191_001381"
     CDS             complement(4770..5516)
                     /gene="rlmB"
                     /locus_tag="TV191_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEL1507886.1"
                     /translation="MKAKEINETKDIVYGVHAVTESLLANTGNKLYIQEDLCGKHVDH
                     IKDLATSKKVSISWTKKKALTEMTAGAVHQGFALRVSAFAYTELDELLELAQQEDNPL
                     LLILDGLTDPHNFGSILRTADATGVCGVIIPKHRAVGVTPVVAKTSTGAVEHVPIARV
                     TNLSQALDQLKANGFWVFGTDVTGTPSYKWNTSGKLALIIGNEGKGISANIKKQVDEM
                     ITIPMMGHVQSLNASVAAAILMYEVFRNKL"
     gene            complement(5565..6353)
                     /locus_tag="TV191_001382"
     CDS             complement(5565..6353)
                     /locus_tag="TV191_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507887.1"
                     /translation="MKPMRNVALVISAMLLLSSQAFVSAVAAQDNQPTIAVQAQAAAE
                     ANVSARMRSDQPVIEANIATSQPVSQSTEATILLKDAKGNAINSTAYTMQAGQSRFSV
                     WFDLTNLKVSDYSISVSVPDKEKAFSGSSAPIHFDGKPTKNTPETEQKNSNPVPANNQ
                     PKPAASGRVTSTEQPQNVPSATASANHMTRTNHRSDKVLKASSSNTPSAAKSIDSAEK
                     GKGMLSDSTAQDKEQKGFPWLLSSLIAITAAALLALVIKAVHRK"
     gene            complement(6570..6977)
                     /locus_tag="TV191_001383"
     CDS             complement(6570..6977)
                     /locus_tag="TV191_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEL1507888.1"
                     /translation="MANSVDVNLINGIALAFVGDAVYSYYIRRHLIFQGQTKPNKLHY
                     LATKYVSAKAQASLIQAMLEAQLLTEKEKDIYKRGRNTNSHTKAKNADVVTYRMSTGF
                     EAIMGYLDMTGQTERLELLIQWCIKQVENSPQS"
     gene            complement(6970..8313)
                     /locus_tag="TV191_001384"
     CDS             complement(6970..8313)
                     /locus_tag="TV191_001384"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEL1507889.1"
                     /translation="MIKIYDTMTRSLREFVPITDKVVNMYVCGPTVYNYIHIGNARSA
                     VAFDTIRRYFEYAGYTVNYISNFTDVDDKIIKAAKESGVSPKELADRFIAAFMEDTKA
                     LGVKPATKNPRVMDYMDEIIAFIAALIKKGYAYESAGDIYFRVAKASNYARLANKTIA
                     DLEAGASGRTDTETALKEDPLDFALWKSAKLGEISWASPWSAGRPGWHIECSVMATEL
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTSKTFANYWMHNGFVNVDNEKMSKSLGNF
                     VTVHDLLKTVDGQTLRFFLATQHYRKPINFTEKAIHDAGVNLKYLKNTLQQPTVATAD
                     ASQLAAFITAFKAAMNDDFNTANGITVLFDMAKWINSGAYSEAVKSAFEEMLAVFGIV
                     FEAESLDTEIEQLIAERQEARANRDFARADAIRDQLAAQGIKLLDTKEGVRWIRG"
     gene            complement(8431..8967)
                     /gene="cysE"
                     /locus_tag="TV191_001385"
     CDS             complement(8431..8967)
                     /gene="cysE"
                     /locus_tag="TV191_001385"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEL1507890.1"
                     /translation="MGWWKDNIDIVKQLDPAARSTLEVILTYPGLKALAAHRLSHFLW
                     QHGFKLLARMHSQFWRFWTQIEIHPGARIASGVFIDHGAGLVIGETAIVEKGAMLYHG
                     VTLGGTGKDRGKRHPTVREGALISAHAQIIGPVEIGKSAKVGAAAVVLTDVPAGVTVV
                     GIPAQIVRVHEKKPSRQD"
     gene            complement(8979..9731)
                     /locus_tag="TV191_001386"
     CDS             complement(8979..9731)
                     /locus_tag="TV191_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SseB family protein"
                     /protein_id="HEL1507891.1"
                     /translation="MTNTNELDIRLRAFINAPDNFLDSVALVNAFHQYPVWAAKKPYA
                     IEIEGVRIFPVFTDKDDMATFKEEQKSAQAQYWVERSALTVLEEAVHAGAAGLGFNLK
                     KKGDFGNSTVFKSADMIQFMNNYTTILNTLMSDDNSAADTLDRLYLVPAFVYPKEEEH
                     YYDRLFPTMSTPEGKRYVPAFSNLQSFAKWYNQEEFGGLFRKSGGVILTWKIADIYQP
                     RNGNNDIDETFGVAIDPFDDQQILVDWSDIDT"
     gene            complement(9724..11868)
                     /gene="pnp"
                     /locus_tag="TV191_001387"
     CDS             complement(9724..11868)
                     /gene="pnp"
                     /locus_tag="TV191_001387"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEL1507892.1"
                     /translation="MSKQTFTTTFAGKPLVVEVGQVAKRANGATVVRYGESTVLTAAV
                     MSKKMSTGDFFPLQVNYEEKMYAAGKFPGGWMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDEDASAPMAAMLGSSLALSISDIPFNGPIAGVQVAYVEGEFI
                     INPDKAQQEASLLELTVAGTKDAINMVESGAKELPEAIMLEALLVGHKAIQELIAFQE
                     EIVAAVGKEKAEVELLQVAADLQAEIIETYNADLQQAIQVEEKKAREAATEAVKERVI
                     AAYEERYAADEEHDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRRVDEIRPLAAEI
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGDTQIIDGLEPEYKKRFLHHYNFPQYSVGE
                     TGRYGAAGRREIGHGALGERALAQVLPSLEAFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGTNYTVLTDIQGLEDHFGDMDFKVAGTRQGITAL
                     QMDIKIEGITPQILEEALAQAKKARFEILDLIEATIAEPRPELAPTAPKIDTIKIDVD
                     KIKVVIGKGGETIDKIIAETGVKIDIDEEVNVSIYSSDQDAINRAKEIIASLVREAKV
                     GEVYHAKVVRIEKFGAFVNLFDKTDALVHISEIAWSRTTNVSDVLEIGEEVDVKVIKV
                     DDKGRIDASMKALVPRPPKPEKSEAKKEGKHD"
BASE COUNT         3535 a         2831 c         2328 g         3485 t
ORIGIN      
        1 aatgtggtag aatatcaatt aggaggaatc tatgactaat aatatagcta aacttataga
       61 agaaagtggc aaaaaaataa aaagtatcag tgaagcgcta gatatatcct acccaacact
      121 atctagctat aaccaaggaa tacgaaaacc taaaaaagag aatgctcaaa agttagcgga
      181 ttattttggt gtctcagtgg catacatcct tggaattgac gaagaaaagt acgctccgtc
      241 aaatttaaaa atcgtcactg atagtttcaa gacatctgaa attacttctg taacaccttt
      301 taaaagcgat atggagaagc ttaagaaagg aatcgaacta ggagagattc atttgtctat
      361 gcccttaaac gaggttttct cagatgactt tagacgtatt ctttctaact acttaatgga
      421 ttatgaagaa acctttatca aagacttaat taagtttatg aataaccaag gccaaaaatc
      481 ggatatttgg aaaacatgga tacaaaccga agagtttcaa attagacgag cagatcgtga
      541 cagaaaatag actaatattt ctcaattaca taagctccga aaacttagaa acggagaact
      601 gttatgtctg tacacaaata ccaatctaca aaaggaatta cctattttgt taaagtttac
      661 cttggtctaa acgactacgg taagaaaaaa tattacacta aacgaggatt caagacgcgt
      721 aaagctgcca aagctcatga aactgctgtt aatcatcagc tgaatagtgg aacttttgcc
      781 catcttactg ctcaaacaac ctatacttac caagaactat atcaaaggtg gtatgaagct
      841 tacaaagata ccgttgaaac aactactgca gctaaaacgg ccgatttata tcgccttcat
      901 attcttccaa cctttggaga gaaaaagatt tcaaaaatca gtccgctaga ctgccaaacc
      961 tttatcacag ataaagcgaa atcattcaag aacatgaagc aaatcaagtc atacacctct
     1021 aaaacctttg aatttgccat caatatgaat catattgaac gtaatcctat gagcaaagtt
     1081 attatgccta aactcaaaaa aactgtcagt gagaactact ggacagttaa cgagttgcat
     1141 cattttttga caatcatttt agaaaatgaa ccttataaac attatgctct atttcgatta
     1201 ctagcataca gcgggttacg aaaaggagag ctctacgccc tcaaatggga agattttgat
     1261 tctgagaatc aactattaac agtcagcaaa agtttaggaa gaatagatgg tcatgccatt
     1321 gaaaaaggaa ctaaaaatac attctcagta cgctctatct atcttgatga tgaaacctgt
     1381 tctatcctca acaaatggaa acaggaaact agcaaagaaa aggggcaatt atcagtacag
     1441 cccctttctc tcgacaaaga atttatgttt acatactgca acagagatgg tgagatagaa
     1501 cccttacacg ctgactatat caacaatatt ctaaaacgca ttatacgaaa gcataatctt
     1561 aaaaagatta gcccacatgg gtttaggcac actcacgcaa ccttgatgat tgaaatggga
     1621 attgacccag ttaataccgc taagcgtcta ggtcatgcta gcagccagat gactttagat
     1681 acttatagtc attctaactt aacctctctt aaaactaggt ctcaacagat taccaaggtg
     1741 cttttttcaa caaaaaagca ccttgcgaaa acttcgcaaa gtgctctgaa acgttggtat
     1801 aactggatat taacgttttg agaactggct agctttacgg gcttttttaa gacctggttt
     1861 tttacgttca accatacgtg cgtcacgtgt aagaagacca gcgcgcttta gtgagtcacg
     1921 gaaatctggg tccacttgaa gaagcgcacg agcgatacca tgacgaatcg cacctgattg
     1981 accagcataa ccaccaccta caacgttaac aaaaacgtcg tatgagcctt cagttgaagt
     2041 cactgcaaaa ggctgattaa tgactaaacg taggtcagca tgtgggatgt attcttcaac
     2101 atctttttta ttaacagtga ttttaccagt acctggaact aaacgaacgc gtgcaacagc
     2161 gtttttacga cgaccagtac ctgcatattg tgcttgtgcc attatttaat gctcctttct
     2221 cttagataag tcctgaaata tcaagtactt ctggttgttg tgcagcatga gtgtgctcac
     2281 cgccaacaaa gacctttaat ttcatacctt gtgcacgtcc aagagtgttg tgtggaagca
     2341 tgccttttac tgacttttca atcaaacgaa cggcattttt agagcgaagc tcaccagcag
     2401 tgattgattt caagccacct gggtacattg agtgagtgta ataaacctta tcagttgctt
     2461 ttttaccagt taatttaacc ttctcagcat tgataacaat aacaaagtca cctgtatcag
     2521 tgtgcggtgt gaaagttggc ttgttctttc cgcgaagtac gctagcaact actgcagaaa
     2581 ggcgtccaag tggcacatct gttgcgtcaa caacgtacca tttgcgttca acttggcctg
     2641 gtttagccat gaaagttgtt ttgttcatga tttctcctat acgaattcgt ttttgtttac
     2701 attagtgatg gatgttccgg tccatcgaag gtatttggaa ggttccgggg cctttcaaat
     2761 ggggtaaaca ataccgtcta ctatagtatc aaacttctta actgatagtc aagtggttta
     2821 gctctatttc tttgattatt tttgcttttt cacaagaaga acaggcttgc ttttgagctg
     2881 gactattagc cttgacttcc ctccaaaaaa tccgctcagt tcctgttagc tcctatgcaa
     2941 ataacaatac aaagattagt ggtggaatga ccaaagctcc tgtcaactgc taaaacattt
     3001 gacatctgac ttctggcaaa tcaaaaagcc ctgttctgtt atgctagttc cttacctgca
     3061 cgcgcacctt cattgtcaaa caattcattc taacttttga ttaaaaataa aaaatgcgaa
     3121 cacccatact cttaagcggc atcacagcta aaacaagcta tagtcgacaa aaaagaattg
     3181 aaacaagcgc ttcaatcctt ttctttttat cttttttcct tgccgatgac aaagaccgct
     3241 aaggtatctg gacctgtatg agcagcaatc accggtccga gcggcagcat aaagacatca
     3301 ctgatacctt catgtgctaa tagctgttct cgtaggtcat ctgccccagt ctgatcacta
     3361 gtataggaca caacaacagt tgaatcagca atatcttttg tggctctgtc agcaatttcc
     3421 ttaatggcct ttttacggcc acgaatcttg gcaataggaa ctaattttcc gctggcatca
     3481 atccataaga gaggcttaat attcactagg ctgcctataa aagcagagcc ttttgacaag
     3541 cgtcctcctc gcacaagatg aaaaagatca tctactaaga aataggtgcg taagcgaggc
     3601 aaaatacctt ctattatcgc tttggtttct aataggcttt ttccattatc acgcgcctcc
     3661 gaggctagca tggtcaaata gccctctcct cctgctgcag ccaagctatc aacaatctca
     3721 attacagcgt ccggatagtc ctccaaaacc agctcacgtg ccatgacagc actttgatag
     3781 gtacctgata ggactgaaga aaaggcgata tataaaagag cttggttatc agctgcgtaa
     3841 tgtcgaaaaa tctcttcaaa ctgaccaaca tttatctggc ttgttttggg ctggctccca
     3901 cttttcatca tagctagcaa agcatcactc gttaatctat ctggaccaac cgtcttgtaa
     3961 accttgccat cacattcaac agttaggcct actatatcga tgttatgctc ctttgcccaa
     4021 aaagaatcta aatccgctgt tgaatctgtc atcaatacaa atgtcatctg aactcccaag
     4081 taacgtcatt atcgtttaat aatcaaatga ttttctcata gtataacaaa aaaatatcag
     4141 ctaagaaagc aataagaacc agctgcctca gaaatgatca ccgttagatc gtatgagctg
     4201 ctctagcagc ctggagaatc atacctagaa aagctagcaa gataagctta ttaatcatct
     4261 aatcgattca taaagtcctt gagctgatta agctgccctt gatcaaaggg acccagtcta
     4321 ggctttttaa gatcaatatc ctgtgacagc ttatctaaat ccgacttaac agcattaaca
     4381 cgctgctcaa gctctttagc agtgacacgc aaggcgcctt gggaaaagat cgtccactgt
     4441 tcattcagat cactagtagc cacctctacc atggttagag cggtgtttag ctcagcagca
     4501 gtccgctcaa tatagctatc agctgtttct tcctcttcgg taaaaataac agaaatccta
     4561 tattggtcat aacgctgtct aagtcctgga acatactgag catcaaatac gcaaataatg
     4621 tcactatcat caaaatgcgc atagttgttc agcttattta gcaagatcct tctagcttga
     4681 tccaattggt ttgtcttaaa aaactgacga gttgattccc aaaaggcaat catgttatag
     4741 ccatcaacca gcaatagtct ttttttcatc tataatttat ttctaaatac ttcatacatc
     4801 aaaatagcag ctgcaacgct agcatttaag ctctgaacat gacccatcat aggaatggta
     4861 atcatttcat ctacctgttt tttgatgtta gctgaaatgc ccttaccctc attgccaata
     4921 atcaaagcca gcttgcctga ggtattccac ttgtatgatg gtgtaccagt tacatctgtc
     4981 ccgaagaccc aaaagccatt tgcttttagc tgatccaatg cttggctaag atttgtcacg
     5041 cgagcaattg gaacatgctc aacagctcct gttgaggtct tagcaaccac tggtgtcaca
     5101 ccaacagcac gatgcttagg gataatcaca ccacaaacac ctgttgcgtc ggctgttctt
     5161 aaaatagacc caaaattatg aggatctgtc agcccatcta ggatgagcag caagggatta
     5221 tcctcctgct gtgccagctc tagcagctca tctagctcag tataagcaaa ggctgacact
     5281 cgaagcgcaa agccctgatg aacagctcct gctgtcattt cggtcaaagc tttctttttt
     5341 gtccaagaga tagacacctt cttactagtg gctaaatcct tgatgtgatc aacatgctta
     5401 ccacacagat cctcttgaat gtaaagctta tttccagtat tggctagtag gctttcggta
     5461 acggcatgga cgccataaac aatatccttg gtttcattga tttctttagc tttcatggtt
     5521 tttattatac cacgaaagca ataaaatagc tcttgctgct ctttttattt cctgtgaaca
     5581 gctttgatga caagagcaag taaagcagct gctgtaattg caattagaga tgatagcagc
     5641 caaggaaagc ctttttgctc tttatcttgg gctgtgctat cagaaagcat gcccttgcct
     5701 ttctcagcag agtctattga tttggcagct gatggtgtgt tgcttgagct tgcctttagg
     5761 accttatcag atcgatgatt ggttcttgtc atatgattgg cgctagcagt cgcgctaggc
     5821 acattttggg gttgctcagt gcttgtcacc ctgccgctag cagcgggttt aggctggtta
     5881 ttagctggta ctggattgct gtttttctgt tctgtctctg gggtattttt ggttggcttt
     5941 ccatcaaaat gaataggtgc tgagctacca ctaaaggcct tttctttatc aggaacactc
     6001 actgatatac tataatcact aacctttagg ttcgtaaggt caaaccatac tgaaaaccgg
     6061 ctttgaccag cctgcatggt ataggctgtg ctattaatcg cgttgccttt ggcatccttt
     6121 agtaaaatag tagcctcagt gctttggcta actggctgac tggtagcaat gttagcttca
     6181 ataacgggct gatctgaacg catacgagca ctgacattgg cctcagctgc tgcctgtgct
     6241 tgaactgcta tggttggttg attgtcctgt gctgctactg ctgatacaaa ggcctgtgag
     6301 cttaacagta acattgctga aataactaag gctacgtttc tcattggttt catagacatt
     6361 ctcctatcat tttattatga ctctttcatt ataaactatt cggaaaattt ttcaatagtt
     6421 ttgttacgtt tttgttacaa atatttattt tatgtttcgt gtgtatctat attgtgacat
     6481 aacttttaaa cacaacataa aaacactctc atgactttga gcgatggcag atcgctagtg
     6541 acacagagaa tgttttagat gattcatcat tatgattgag gactgttctc cacctgcttg
     6601 atacaccact ggatcaacag ttctagccgt tctgtctgac ctgtcatatc aaggtagccc
     6661 ataatagctt caaagcctgt tgacatacga taggttacta catcagcatt tttagccttg
     6721 gtatggctgt tggtattgcg gcctcgtttg tagatgtctt tttctttttc ggtcaatagt
     6781 tgtgcttcta gcatggcctg aatcagagaa gcctgtgcct ttgcagaaac atattttgtt
     6841 gcaaggtagt ggagcttatt tggcttggtc tggccttgga aaatcagatg acgacgaata
     6901 tagtaagaat aaacagcatc accaacaaag gcaagggcaa tgccattaat caaattgaca
     6961 tcaactgaat tagccacgta tccacctcac accttctttt gtatccaaca gcttgatccc
     7021 ctgagctgcc aactgatccc gaatagcatc tgcccttgca aaatctcgat tggcacgtgc
     7081 ctcctgacgc tcagcaatca gctgctcaat ctctgtgtct aggctttctg cttcaaagac
     7141 aatgccaaaa acagctagca tctcttcaaa tgctgatttg acagcctcag aataggcgcc
     7201 ggagttaatc cattttgcca tgtcaaataa gactgtaatc ccatttgctg tattaaaatc
     7261 atcattcatg gctgctttga aggcagtgat aaaggcagca agctggctag catctgcagt
     7321 ggctactgtg ggctgctgaa gcgtgttttt caagtatttg aggttaactc cagcatcatg
     7381 aatagctttt tcagtaaaat taatcggctt acgataatgc tgagtagcca agaaaaagcg
     7441 tagcgtttgc ccatccaccg tctttagcag atcatgaaca gtcacaaagt tgcccagtga
     7501 cttagacatt ttttcgttgt caacattaac aaagccatta tgcatccagt aattggcaaa
     7561 agttttgcta gtttttgctt ctgattgagc aatttcattg gtatggtgtg ggaattccag
     7621 gtctgcgcca ccaccatgaa tatcaatggt atctcccaaa agctcggttg ccattacaga
     7681 gcactcgata tgccagccag gacgaccggc gctccaagga cttgcccaag aaatctcgcc
     7741 tagctttgct gatttccata gggcaaagtc caaaggatct tccttgagag cagtttcggt
     7801 atctgtacga ccactagcac cagcctccaa atcagcaatc gttttattag ccagtctggc
     7861 ataatttgat gcctttgcca cgcggaaata aatatcacct gccgactcat aggcatagcc
     7921 ttttttgatt aaagcagcga taaaggcaat gatctcgtcc atatagtcca tgacgcgtgg
     7981 atttttggtg gccggcttca caccgagtgc cttggtatcc tccataaagg cagcaataaa
     8041 tctgtccgcc aattccttgg gtgatacacc tgattccttg gctgccttga taatcttatc
     8101 gtctacatct gtaaaatttg aaatgtaatt gactgtatag cctgcgtatt caaagtagcg
     8161 acgaatcgta tcaaaggcca cagccgaacg tgcattgcca atgtgaatat aattgtaaac
     8221 cgttggcccg cagacataca tattgaccac cttatcagtt attggtacaa actctcgcag
     8281 acttctggtc atggtatcat agatttttat catcactttt cccttttgtt tttatccttt
     8341 tctcctagac tgcgcaagct gtcagcaact gaggtaagca tagggctcta actctcccgt
     8401 tttttggctg actgcctcta gagaaaacta ttaatcctgc cttgagggct ttttctcatg
     8461 cactcgaaca atttgggctg gaatgccaac gaccgtcacg ccagcaggta catcagtcaa
     8521 cacaacagct gcagctccaa ccttagccga tttcccaatc tcgacaggac cgataatttg
     8581 agcatgggca gaaatcagtg ccccctcacg aacagtaggg tgccgcttcc ctcgatcttt
     8641 tccagttcca ccaagcgtca ctccatgata aagcatggct cctttttcaa caatggccgt
     8701 ctcaccaatc accaagccag ccccatggtc aatgaaaaca cctgaagcaa tcctagctcc
     8761 tgggtggatt tcaatctgtg tccaaaatcg ccaaaactgg ctatgcattc gagccagcag
     8821 cttaaagcca tgctgccaca aaaaatgtga cagcctgtgc gctgccaagg cctttaatcc
     8881 agggtaggtt aggataacct ctagggtgct acgtgcagca ggatctagtt gctttacaat
     8941 atcaatattg tccttccacc agcccattta aactcctttt atgtgtcaat atcagaccaa
     9001 tcaacaagaa tctgctgatc atcaaagggg tcaatagcaa ccccaaaggt ctcgtctatg
     9061 tcattattgc catttcttgg ctgataaatg tctgctatct tccatgttaa gataacacca
     9121 cctgatttcc taaaaaggcc gccaaactcc tcttgattgt accatttagc gaagctctga
     9181 agatttgaaa aggcaggaac ataacgcttc ccctctggag ttgacatggt tggaaaaagc
     9241 ctgtcatagt aatgctcctc ttccttaggg taaacaaagg ccggcaccag ataaagccta
     9301 tccagggtat ctgctgcgct attgtcatca ctcatcaagg tattcaaaat cgttgtgtaa
     9361 ttgttcataa actgaatcat atcagcagac ttgaacactg tagaattgcc aaaatctccc
     9421 tttttcttga gattaaagcc tagcccagca gcacctgcat gaacagcctc ctccaagaca
     9481 gtaagagcag agcgctctac ccaatactga gcttgtgcac tcttttgctc ctctttaaag
     9541 gtcgccatgt cgtccttatc tgtgaataca ggaaaaatcc ttaccccttc aatctcaata
     9601 gcatagggct tttttgctgc ccacaccgga tactggtgaa aagcattaac caaggccacg
     9661 ctatctaaaa aattatcagg ggcattgata aaggctctta aacgaatatc tagttcattt
     9721 gtattagtca tgtttgcctt ctttttttgc ttctgatttt tctggctttg gcgggcgtgg
     9781 caccaaggct ttcattgatg cgtcaatacg tcccttatca tcaaccttaa taaccttaac
     9841 gtcaacctct tcaccgattt caagaacatc tgagacattg gtagtgcggc tccaagcaat
     9901 ttcagagata tgcaccagcg catctgtctt gtcaaagagg ttaacaaagg caccaaattt
     9961 ttcaatacgg acaaccttag catggtagac ctctcctacc ttagcctcac gtactaggct
    10021 agcaatgatt tccttagcac gattgatagc gtcctgatca cttgagtaga ttgaaacatt
    10081 tacttcctca tcaatgtcaa tcttaacacc tgtctcagca ataatcttat caatggtttc
    10141 gccaccctta ccaataacca ccttaatctt atcaacatca atcttgatgg tatcaatctt
    10201 tggtgctgtt ggtgccaatt ctggacgagg ctcagcaatg gttgcctcaa tcaagtcaag
    10261 aatttcaaag cgagcctttt tagcctgcgc caaggcttct tctaggattt gaggggtgat
    10321 accttcgatc ttgatatcca tttgcagtgc tgtaatccct tggcgtgtcc cagcaacctt
    10381 gaagtccatg tcgccaaaat gatcctctaa cccctgaatg tctgttaaaa cagtataatt
    10441 ggtcccatca gagataagtc ccatagcaat acccgcaacc ggtgccttga tcggcacacc
    10501 accagccatc aaagcaagcg tccctgcaca gatagaggcc tgcgaggaag aaccgtttga
    10561 ttccaatacc tcagccacta gacgaatagc atatggaaat gcctcaaggc ttggaaggac
    10621 ttgtgcaaga gcgcgctcgc ctaaagcacc atgcccaatt tcacgacgcc ctgctgcacc
    10681 gtagcggcct gtctcaccaa cagaatattg agggaaatta tagtggtgca agaagcgttt
    10741 tttgtactca ggctcaagcc catcaataat ttgagtatct cccattgggg ctagagtcaa
    10801 gacagacaaa gcttgagttt gaccgcgcgt aaagaggcct gagccatgca cccttggtaa
    10861 gaaatcaatc tcagcagcaa gcggacgaat ctcatcaaca cgacgaccat caggacgaac
    10921 cttatcctca gtgatgaggc gacgaacctc agcatgctcc atttgctcca aaatttcagc
    10981 cacatcacgc atgatacggt catgctcttc gtctgctgca taacgctcct cgtatgcagc
    11041 tatgacacgc tccttgacag cctcggttgc ggcttcacgt gcttttttct cctcaacctg
    11101 aatagcctgc tgcaaatcag cattgtaagt ctctatgatc tcagcctgca aatcagcagc
    11161 aacctgtaat agctctacct cagccttttc cttgcccacc gctgcaacaa tctcttcttg
    11221 aaaagcaatc aactcctgta tagccttatg gccaaccaaa agtgcttcta gcataatagc
    11281 ctctggcaat tccttagcac cagattcaac catattgatc gcatcttttg ttcctgctac
    11341 ggttaactct aataatgaag cctcctgctg ggccttatca ggattgatga taaattcacc
    11401 ctcaacatag gccacctgaa caccagcaat cggcccatta aaaggaatat ctgaaatcga
    11461 tagggctaat gagctaccaa gcatagcagc cataggggca ctagcatctt cgtcataaga
    11521 caggacagta ttaatcacct ggacctcatt acgaaagccc tcagcaaaca taggacggat
    11581 agggcggtca atcaagcgag cggttaaggt cgcatctgtt gacggacgtc cctcacgctt
    11641 catccagcca ccgggaaatt tacctgcggc atacattttt tcttcataat tgacttgaag
    11701 cgggaaaaag tctcctgttg acatcttctt agacatgaca gcagcagtta gcactgtaga
    11761 ctccccataa cgaacgacag tggcaccatt tgctcgcttg gctacttgac cgacctcaac
    11821 aacaagtggt ttgcctgcaa aggttgttgt aaatgtttgt tttgacattc tttctccttg
    11881 aacgagctag cctaccatag ccgtttgacc cgaccaaagc ttgctagcct tttatttttt
    11941 atggctatac gttgttttgc tacaaagagc aatctgtaag gaattacaca ctcctctttg
    12001 tatcaaacga cgtatctgct acattttacc ataaaatagt taaaaattca cgaccctaaa
    12061 aggcattcct agaaaaagtt tgaaagggct gtcaatacca gcagcactct cttttatcac
    12121 tatagcccta cagccaagca cgctaagccg ctgatgacgc agcaaaaaaa gacctgcct
//
LOCUS       DARYXW010000062        12157 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.062, whole genome shotgun sequence.
ACCESSION   DARYXW010000062 DARYXW010000000
VERSION     DARYXW010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12157
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.062"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(152..433)
                     /locus_tag="TV191_001388"
     CDS             complement(152..433)
                     /locus_tag="TV191_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEL1507893.1"
                     /translation="MTTQKAYMYVLECADKTLYTGYTTDLDKRLKAHNAGKGAKYTRC
                     RLPVSLLYYESFDSKQAAMRAEALFKKRNTRQQKLTYIAEQQNKKAKPD"
     gene            complement(466..1233)
                     /locus_tag="TV191_001389"
     CDS             complement(466..1233)
                     /locus_tag="TV191_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEL1507894.1"
                     /translation="MLHSILKDGERIDQLFSSDVQIIQNKEVFSYSIDSVLLSRFPKL
                     PSRGLIVDLCSGNGAVGLFDSTQTKASIVEIELQPRLADMGQRSIRLNQLEDQVTMIC
                     DDLTNLLQHVPRSGVDIILYNPPYFKSSQTSKKNLSEHYLLARHEITTNLAKICQIAR
                     HALKSNGRLAMVHRPDRFLEILDTLKINGLAPKRLQFVYPKLGKEANMLLIEAIKDGS
                     MEGLKILPPLIVHKDNGDYTDTIKEIYFGAKDKAFKN"
     gene            1352..2092
                     /locus_tag="TV191_001390"
     CDS             1352..2092
                     /locus_tag="TV191_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEL1507895.1"
                     /translation="MFYVYLRGLVVFLLWVVNGNAHYHNEDRILDKSENYILVAPHRT
                     FWDPVYMAFAARPKQFIFMAKKELFTNRLFAWWIKMCGAFPIDREKPSPDAIRYPVNM
                     LKKSNRSLVMFPSGSRHATDVKGGVAVIAKMAKVKIMPAAYQGPMTLKGLLAGERVDM
                     NFGHAIDVSDIKRMNDEEIEEVARRIQAEFDRLDQEMAPFKSNQRRSMLTYLYRIPLG
                     ILLVLILALTMLFSYLASFVWDPDKHRS"
     gene            2411..3091
                     /locus_tag="TV191_001391"
                     /pseudo
     CDS             2411..3091
                     /locus_tag="TV191_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184716.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
     gene            3072..5315
                     /locus_tag="TV191_001392"
     CDS             3072..5315
                     /locus_tag="TV191_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEL1507896.1"
                     /translation="MRFPLTKYFPIAPIQFALLVLVLHYLIYRPSWLTAGLLAGLLVL
                     LGYRFVLKQVLKTLLLLGLFGCLFAYQKGQLEANQINQPDRLSTVELIPDSIMVNGDH
                     LSFIGRHSGHHYQLAYRMTSKEEADFFKQQSQFLKLKADIRLEEAAGLRNFKGFNHQA
                     YLAYQGIFRVGKIKSLQSLKTISPRSVSDRISQWRRQAIVWCQSRFPQPMSHYMTGLL
                     FGYLDKSFGQMTELYSQLGIIHLFALSGMQVGFFLTYLRRGLVWLHIPIDKIKLLEVV
                     CSFCYSGLTGHSISVIRSLLQAQLRHIGLTGLDNLAMTFLMMFLINGHFLMSIGGVLS
                     FAYAFIIATVRFEELSGNKQRLLKALAISFGIVPLLAYYFSVFNPISVVLTALLAYLF
                     DGLILPGLAILFFFSPLAVVTAVNPFFLYLEKGIGMIGSYFSAPLVLGSPTALQLCLC
                     MACLAIVYDYRGNRGLQLVAGGLLLLTLFTVKWPMTNEVTLVDVGQGDSIFIRDKQNH
                     TMLIDVGGVPAPQEKEQWRRKYQACNAHKTLIPYLRSRGVDTIDQLVLTHTDTDHVGD
                     MEAVVKAFRVKQIYVSQGSLTNASFVKRLQGLAAKVKAISAGDHLPIMGSFLEVLYPW
                     EIGDGKNNDSLVLYGRLLDKSFLFTGDLEAEGEERLIARYPKLKADVLKAAHHGSKGS
                     SIPAFLDHIQPQLSLISAGRNNQYQHPNPETLARFEARHIPYYSTASKGAIRLTGQAH
                     WQLESCR"
     gene            5428..6489
                     /locus_tag="TV191_001393"
     CDS             5428..6489
                     /locus_tag="TV191_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEL1507897.1"
                     /translation="MIAIEKIDALSKESLGLITVVTGEDIGQYSHMKALLLKKIAFDP
                     ADLTYSYFDMSEALYQTAEMDLVSMPFFADQKVVIFDHLLDITTSKKSYLKEKELKAF
                     EDYLENPVETTRLVIFAPGKLDGKRRLVKILKRDALIFEASPLKAAEKRTYFQKYSHQ
                     LDLSFASGAFDQLLLKSNDDFSQIMKNMTFLKAYKKSGPITVEDIAQAIPKSLQDNVF
                     DLTRLVLQGKIDAARELVHDLRLSGEDDIKLIAIMLGQFRLFLQLATLVRSGKTEQQL
                     VTSLSDLLGRRVNPYQVKYALKDSRALSLSYLQLAVKTLIETDYHIKTGVYTKDYLFD
                     LALLKLVAHSQGNTDLSDL"
     gene            6567..7172
                     /locus_tag="TV191_001394"
     CDS             6567..7172
                     /locus_tag="TV191_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEL1507898.1"
                     /translation="MTITLPDLPYAYDALEPYFDTETMTLHHDKHHATYVANTNTALE
                     KYPELGENLEELLADVSSIPADIRQAVINNGGGHLNHALFWELLSPEKQEVSADVAAA
                     IDDAFGSFAAFKEQFTAAATGRFGSGWAWLVVNKAGQLEITSTANQDTPISEGKQPIL
                     ALDVWEHAYYLNYRNVRPNYIKAFFEIINWKKVSEFYQAAK"
     gene            complement(7423..8637)
                     /locus_tag="TV191_001395"
     CDS             complement(7423..8637)
                     /locus_tag="TV191_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEL1507899.1"
                     /translation="MKYIHSGLMFLLFVLFVVSFAKHEQARLAFEQSHQAYKDMVISF
                     EKRHIKQQPSSLSDQFQLRKDLLHYAKKLAQDGWSYEAIEKGYLGHLKPKQASYNFEQ
                     LYQSLQIIGSPAFHRMWERQPRAQHKLEAKRDLSLLLSYVKMPEELSGQSAETKQLLK
                     QFSPSLSPTDAFWDQLASLIQLYYDHLEHIPYQTFNRKLYQLRYVLSVQQIEWVRNNY
                     GRAGKTDADALARYLATLDESDYSLNESARYHNKVASHLDTANQLQITYPDNFPQANY
                     KILIHFHSEFILSEAGHFLAALDPQQPSQNGLINGSSFNYANQNNDLHRLLDIEPIEL
                     FEPDFIETAMINLDSPFIVPDLEQQNDQQHPIFSRDGKSSKQLTKAAAKAFKKLLRHY
                     QQAHQSFPSKTP"
     gene            complement(8647..9675)
                     /gene="queA"
                     /locus_tag="TV191_001396"
     CDS             complement(8647..9675)
                     /gene="queA"
                     /locus_tag="TV191_001396"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEL1507900.1"
                     /translation="MNTNDFDFELPEELIAQTPLEQRDRSKLLIIDHQEHTMTDSHFD
                     HIIDQLEPGDALVMNNTRVLPARLYGEKMETHGHVELLLLKNIQGDQWEVLAKPAKRL
                     KAGAQISFGDGRLKARVIQELEHGGRIVEFSYDGIFLEILETLGEMPLPPYIHEKLAD
                     AERYQTVYAKENGSAAAPTAGLHFTQELLQKIEAKGVHLVYLTLHVGLGTFRPVSVDN
                     IDEHDMHSEFYLLSEEAAQTLRKVKAAGGRIIAVGTTSIRTLETIGSKFQGQILADSG
                     WTNIFIKPGYQFKVVDAFSTNFHLPKSTLVMLVSAFAGRDFVLEAYKHAIDEHYRFFS
                     FGDAMFVK"
     gene            9943..10647
                     /gene="nagB"
                     /locus_tag="TV191_001397"
     CDS             9943..10647
                     /gene="nagB"
                     /locus_tag="TV191_001397"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEL1507901.1"
                     /translation="MKIIRVQDQLEGGKVAFSLLKESLAKGATTLGLATGSTPITFYQ
                     ELVNSDLDCSALTSINLDEYVGLPVENDQSYDYFMRDQLFNAKPFKESFLPNGLADDL
                     EAEVKRYDQVIAEHPIDFQILGIGRNGHIGFNEPGTSFAEKTHVVDLQASTIEANSRF
                     FASIDDVPKQAISMGIASIMASKMIVLLAFGKEKAAAIKGMVSGPVTEALPASVLQQH
                     GNVVVIIDEAAASELD"
     gene            10819..11535
                     /locus_tag="TV191_001398"
     CDS             10819..11535
                     /locus_tag="TV191_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEL1507902.1"
                     /translation="MRLDKLLEVTGFGSRNQVKQLIKGRSVLIDGQPARAGCQSVDSG
                     LQVIMVNGRQIKAFAHRYYLLHKPAGVVSACSDRKHQTVIDLIRKEDRVANLYPIGRL
                     DRDTTGLVLLTDNGPLGFRMLHPKHHVNKTYLVTVNGSLAADAVPFFENGVTFLDGTR
                     CKSAALRIIKADQMESQAEVTLSEGKYHQIKKMFLSYGLKVTQLKRIGFAEIALGDLA
                     EGAYRQLTVKEKKLIKTYLT"
     gene            11627..>12157
                     /locus_tag="TV191_001399"
     CDS             11627..>12157
                     /locus_tag="TV191_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEL1507903.1"
                     /translation="MLTALDQDQRVISLTDGSSPSRKQAFTCPACGAAVRLKKGRIIR
                     PHFAHISLSHCQYLTENESHEHLRLKADLYRSLSRSETAEVEAYLPDLNQIADLLVNK
                     HLALEIQCSQLPIKRLEQRSRAYQANGYQVRWLLGRKLWLQKRLTGLQRQCLYFSWQL
                     GFHLWELDVEHHLIRLK"
BASE COUNT         3303 a         2348 c         2832 g         3674 t
ORIGIN      
        1 aagtccttgg aggttttgtt ttgctgcttt tttggtcttg gtctttagta gccttgggca
       61 agcggagctt tgacctagtg tgggtctgtc tcaactgttg tcagctagtc ccatagtggt
      121 gcttggccgc ggcttaggag gcgtcaggag cttagtctgg cttcgctttt ttattttgct
      181 gctctgcaat ataggtgagc ttttgctgtc tggtgtttcg ttttttaaac aaggcttcgg
      241 ctctcatcgc agcctgcttg ctatcaaagc tttcataata cagcaggctg acaggtaagc
      301 gacagcgtgt gtattttgct cctttaccag cattatgggc tttgagacgc ttgtctaaat
      361 ctgttgtata gccagtatag agggttttgt ctgcacattc taaaacgtac atgtaagcct
      421 tttgagttgt catgatgaaa aaacctcttg atgcagaaga gcctgctagt tcttaaaagc
      481 cttgtccttg gctccgaaat aaatctcctt aattgtatcg gtatagtctc cgttgtcttt
      541 atggacaata agtggtggca ggattttcaa gccttccata gaaccatcct tgatggcctc
      601 aatcaagagc atgttagcct ccttaccaag ctttgggtag acaaattgca gccgctttgg
      661 agcaagaccg tttattttta aggtatcaag aatctctaaa aagcgatcag gtcgatggac
      721 catagctaga cgaccattgg acttgagcgc atggcgtgct atctgacaga tcttagccag
      781 atttgttgtg atttcgtgtc tggctaggag ataatgctca gataggtttt tctttgaggt
      841 ctgactgctt ttaaagtaag gaggattata aagaatgatg tcaacacctg agcgaggcac
      901 atgctgaagc aggttagtca aatcatcaca aatcatcgtc acctgatcct ccaactgatt
      961 gagcctgata gagcgctgtc ccatatcggc taagcgtggc tgaagctcaa tttcaacaat
     1021 agaggccttg gtttgtgtac tgtcaaataa gcccactgcc ccatttcctg aacacaaatc
     1081 tacaatgagc ccacgtgatg gaagctttgg aaagcgagaa agcaagacac tatcaataga
     1141 gtagctaaag acctctttgt tttgaataat ctgaacgtcg cttgagaaaa gctggtcaat
     1201 ccgttcacca tcttttaata tcgaatgtag catatcatta ttatagcaaa aataatccta
     1261 tcagagtagg gggtgctgat tgagctttcc ctttaatatt aaaatatttc atggtacaat
     1321 gagtaggatt ataagtgaaa aggagactga tgtgttttac gtctatttac gtggcttagt
     1381 tgtcttttta ttgtgggttg ttaatggtaa tgcccactac cataatgagg ataggattct
     1441 tgataagtct gaaaattata ttctagttgc tccgcatagg accttttggg atcctgttta
     1501 catggcattt gccgcacgtc caaagcagtt tattttcatg gccaaaaaag agctcttcac
     1561 caatcgttta tttgcctggt ggattaagat gtgtggagcc tttccgattg atcgcgaaaa
     1621 gcctagtcca gatgccatta gatatcctgt taatatgctg aaaaaaagca atcgctcttt
     1681 ggtgatgttc ccaagtggga gccgtcatgc gacagatgtc aaggggggcg ttgctgttat
     1741 tgccaagatg gccaaggtca aaatcatgcc agcagcctat cagggtccta tgaccttaaa
     1801 gggcttatta gcaggtgagc gtgttgatat gaactttggt catgcgattg atgtttccga
     1861 cattaagcgt atgaatgatg aggagattga ggaggtagct aggcgtattc aggctgaatt
     1921 tgaccgctta gaccaagaaa tggctccctt taagtctaat caaaggcgct ctatgctgac
     1981 ctatctttac cgtattccat taggaatact tctggtgctt attttggctt taaccatgct
     2041 attttcttat ttagcaagct ttgtttggga tccagacaag caccgctctt aggtcgtgtt
     2101 atggattagc gctgaaggcg cgcaaaaatc agggctttgt tgctactcta ctgagactgg
     2161 cttgcagtta cccttctgac atgttatgtc taggatacga atgctactgg ttactcaagg
     2221 ctacaagaaa gccagcactt tccacagtaa ggggattagg taagccaagg taggttatgc
     2281 ttgtagtgta gctgtatgtt acaatttgat gaggttgaag aggtagtcca ttttggactg
     2341 ctttttttaa tatgctagaa aataggacaa ttttaaaggc ttttatcgaa taatatattg
     2401 aggtgaaaac atgttagaag aattgttctt aaagagtaaa gagatgataa agtcccctta
     2461 ttttctgtca cgttgtgtta ctggtgtgct gtctgtaggg cttttgctgg tgctgtggat
     2521 tgccttgact ggcaaggaaa aagcaagaga ggagtcagct ccatttcctg accattctca
     2581 ggttcagcag tcagaaaagc cagctcagct agaagctagt gagcaagaaa tggcggcagc
     2641 tgaggatatc gtagtggata ttaagggagc tgttcataag gagggtgtct ataagcttgc
     2701 taagggaagt cgtatcacag atctgattga gctagcaggt ggcttgacag accaagctga
     2761 taaaaatgct attaatctag ctgaaaagct atctgatgaa aaggtcgttt atgttgctaa
     2821 gctgggtgag aatatatcag tcattaaagg atcttcagct gaggctcaat cagcgtctgc
     2881 tgatcatcag aagcctgaaa aggttcattt gaacagagct agtcttgctg atttgcaaag
     2941 cattccaggc attggtgcaa agagagcata ggatattatt gatgtacgag aaagcctggg
     3001 tggctttaaa tctctagaag atctgagaaa ggtatcaggt attggtgcta aaacactgga
     3061 gaagctaaag catgagattt cccttgacta agtattttcc aattgctccg atacaatttg
     3121 cccttttagt gcttgttttg cattatttga tttatcgacc tagctggtta acggctggtt
     3181 tgttagctgg cttgttggta ttattaggct atcgctttgt cctcaagcag gtcttaaaga
     3241 cgcttctttt gctagggctt tttggctgtc tttttgctta tcaaaagggt cagctagagg
     3301 ctaatcagat caatcagcct gatcgcttat caacggttga gctgattcca gattcgataa
     3361 tggtgaatgg tgatcaccta tcctttatcg gtcggcactc ggggcatcat tatcagttgg
     3421 cttatcgcat gacctcaaaa gaagaggcag atttttttaa gcagcagagc caatttctaa
     3481 agctaaaggc tgacatcagg ctagaggaag cagcagggct tagaaatttt aagggcttta
     3541 accatcaggc ctatttagct tatcagggaa tctttagagt aggaaaaatc aaaagcttgc
     3601 agtcattgaa gactatctct cctaggtctg ttagtgatcg tattagccaa tggcgacgtc
     3661 aggccatcgt ttggtgccaa tctaggtttc cacagccgat gagtcattat atgacaggat
     3721 tgttatttgg ctatcttgat aagtcctttg ggcaaatgac agagctatac agccagctcg
     3781 gtattatcca tctgtttgct ttatctggta tgcaggtcgg cttttttctg acctacctgc
     3841 gtcgtggctt ggtctggtta catattccaa tagacaagat taagctactg gaggtggtat
     3901 gttcattttg ctattctggt ttgactggtc atagtatttc tgtgatacgt agcttgctgc
     3961 aggcccagct gcgtcatatt ggtttgacag gactagataa tctagcaatg acttttttga
     4021 tgatgttttt gattaatggt cactttctga tgtctattgg tggtgtcttg tcctttgctt
     4081 atgcttttat cattgctacg gtcagatttg aagagctttc tggcaacaaa cagaggcttt
     4141 tgaaagcctt agccatttcc tttggcattg tgcccttgct ggcctactat ttctcggttt
     4201 ttaatccgat ctcggtagta ttgacagcct tattagccta tttgtttgat ggtcttattc
     4261 taccaggtct agcgatcttg tttttcttct cgccccttgc tgttgtgact gccgtcaatc
     4321 cattcttttt atatttagaa aaggggatcg gcatgattgg aagctatttt agtgctccct
     4381 tggtgttagg aagtcctaca gccttacagc tttgcctttg tatggcttgc ttggctatag
     4441 tgtatgatta tcgagggaat cgaggcttac agttggttgc aggtggtttg ttgttgctga
     4501 cgctatttac ggtaaaatgg cccatgacta atgaggtaac gcttgtagat gttgggcaag
     4561 gagacagtat ttttattagg gataagcaaa atcataccat gctgattgat gtcggaggag
     4621 tgcctgctcc tcaggaaaag gagcaatggc ggaggaaata ccaagcctgt aatgcccaca
     4681 aaacactcat tccctatctt agaagccgag gagtagatac gattgatcaa ttggtgctaa
     4741 cccacaccga tactgatcat gtgggggata tggaggctgt tgtgaaggcc tttagagtta
     4801 agcaaatata tgttagtcag gggagtttaa ccaatgctag ctttgtcaag cgattacaag
     4861 gattagctgc caaggttaag gccattagtg ctggtgatca cttgcccatt atgggaagct
     4921 ttttagaggt gctctatcct tgggagatag gagatggtaa aaacaatgat tctttagtcc
     4981 tttatggcag gctattggat aaaagctttt tatttacagg tgatttggag gcagaaggag
     5041 aagaaaggct gattgctcgt tatcctaagc ttaaggctga tgttttaaag gcagctcatc
     5101 atggttctaa gggctcttct ataccagcat ttttagacca tatccagcct cagctaagct
     5161 tgatttcagc aggaaggaac aaccagtatc agcaccctaa ccccgaaacc ttggcacgct
     5221 ttgaagcgag acacattcct tactacagca ccgcaagcaa gggcgctatt cgcttaacag
     5281 gtcaagctca ctggcaatta gaatcctgta gataggctca ttgaaccaga gatatatgca
     5341 agggcctagg tctgggaatg aagtagagaa tgaaaaagat cagctttagc aaggtcatat
     5401 ttagtaagaa aatgctataa taaaaccatg attgcgatag aaaaaataga tgccttaagc
     5461 aaagaaagct taggcttgat tacggtcgta actggtgagg atattgggca atatagccat
     5521 atgaaggcgc tgctactaaa aaaaatagcc tttgatccgg ctgacttgac ttattcttat
     5581 tttgatatgt ctgaggcttt gtatcaaaca gctgagatgg accttgtaag catgcccttt
     5641 tttgctgacc aaaaggtggt tatttttgat catctgctgg acattaccac tagtaaaaaa
     5701 agctacctaa aggaaaaaga gctaaaggca tttgaggact atttggaaaa tcctgtagag
     5761 accacacgtt tggttatctt tgcaccagga aagcttgatg gcaagcgtcg tttggtcaag
     5821 attctcaagc gtgatgccct tatttttgaa gccagtcctt taaaggctgc tgaaaaaagg
     5881 acctattttc aaaaatacag tcaccagctg gacttgagct ttgctagtgg tgcttttgat
     5941 caattgctgt tgaagtcaaa tgatgatttt agtcaaatca tgaagaatat gaccttcttg
     6001 aaggcctata aaaaaagtgg tcctatcaca gtagaggaca ttgctcaagc gattcccaag
     6061 agcttgcagg ataatgtctt tgacttgaca agattggtgt tacaaggaaa gattgatgct
     6121 gctcgggagc tggttcatga tttgcgccta tctggcgagg acgatattaa gcttattgcc
     6181 attatgctgg ggcagtttcg tctgtttttg cagctggcaa ccttggtgcg gtctggaaaa
     6241 acagaacagc agctagtcac tagcctatca gacctgttag gcagacgtgt taatccctat
     6301 caggtgaaat atgcactcaa ggattctaga gccttgtctc tctcttattt gcagctggct
     6361 gtaaagacct taattgaaac agattatcac attaaaacag gtgtttacac aaaggattat
     6421 ctttttgacc ttgctctctt aaagctagta gcgcattctc agggaaatac tgacctctca
     6481 gacctatgag catcaatcaa attagttgaa agcctctatt ttttgagata agatagactt
     6541 atcataaagg aaaagaggaa agagacatga ccattacatt accggatctt ccgtacgcat
     6601 atgatgccct tgagccttat tttgacacag aaacaatgac gcttcatcat gataagcacc
     6661 atgccaccta tgtggctaat accaacactg ctttggaaaa atacccagag ctaggagaaa
     6721 atttagagga attattagca gatgtaagca gcattcctgc tgacattcgt caggctgtga
     6781 ttaataatgg cggtggccat ttgaaccatg cgcttttctg ggagctgctt tctccagaaa
     6841 agcaagaggt ttctgctgat gtcgcagcag ctattgatga cgcttttggt tcctttgctg
     6901 cctttaaaga gcaattcaca gcagcagcta cgggtcgttt tggctcaggt tgggcctggc
     6961 tggttgtgaa taaggctggt cagcttgaaa tcacatcaac tgctaatcag gacacaccaa
     7021 tctcagaggg caagcagcct attttagcac ttgatgtttg ggagcatgct tattacctca
     7081 attaccgcaa tgttcgtcca aattatatca aggccttctt tgaaatcatt aattggaaaa
     7141 aggtctcaga gttttaccaa gctgcaaaat aatagaagtc agttaccaat ctcagaagta
     7201 gattggtttt ttaagtgtgc taataaacta ctagtgttgg tggtaaaagc ctccaagtct
     7261 tttgaaaata ttctctaacg tgatagacaa tacgtgtaac gttcagagtg tatttgatag
     7321 cttagaagct ttataaaaag ccctgccatc tctctagcga atttacccac tagagagatg
     7381 atagagctgt tttttggtta ttggatctac ctcatacctc agctaggggg tcttgctggg
     7441 aaagctttga tgagcttgtt gataatggcg aagtaatttt ttaaaggctt tagccgctgc
     7501 tttcgttaat tgcttggagg atttgccatc tcggctaaaa atagggtgct gttgatcatt
     7561 ttgctgctct aaatctggta ctataaatgg actatcaagg tttatcattg ctgtttcaat
     7621 gaaatcaggc tcaaatagct caatgggttc aatatcaagc aatctatgca gatcattgtt
     7681 ttgattggca tagttaaagg aagacccatt gatgagacca ttttgacttg gctgttgagg
     7741 atctagggca gccaagaaat gaccagcctc tgataaaata aattctgagt gaaaatgaat
     7801 taaaatctta taattggctt gggggaaatt gtctgggtat gtgatttgga gctgattggc
     7861 tgtgtctaaa tgactagcta ccttattgtg gtatctggct gattcattaa gactataatc
     7921 agattcgtct agggtagcta ggtatctagc caaggcatca gcatctgttt ttcctgctct
     7981 cccataattg tttctaaccc attctatttg ctgcactgac aggacatagc gcagctgata
     8041 gagcttgcga ttgaaggtct gataaggaat atgctccaaa tgatcataat aaagctgaat
     8101 taatgatgct aattggtccc aaaaggcatc tgtcgggctt aaggacggac tgaattgctt
     8161 gagtaattgc tttgtttcag cgctttgccc acttaattcc tcgggcattt ttacatagct
     8221 caaaagtaag ctgaggtctc ttttagcttc aagcttatgt tgagcccttg gctgcctttc
     8281 ccacatgcga tgaaaagcag gagacccaat gatctgcagg ctctgataaa gctgctcaaa
     8341 gttatagctt gcttgcttag gcttgagatg gcctaggtag cccttttcaa tggcctcata
     8401 ggaccacccg tcctgtgcta gctttttggc ataatgcagc agatctttcc tgagctgaaa
     8461 ctgatcagat aggcttgagg gctgttgttt tatatgccgc ttttcaaagg aaataaccat
     8521 gtccttgtaa gcttggtggc tctgctcaaa ggccagcctt gcttgctcat gctttgcaaa
     8581 gctaacaaca aacagcacaa ataataaaaa catgagcccg ctgtgaatgt atttcatcat
     8641 taggctttac ttaacaaaca tggcatcacc aaagctaaag aagcggtaat gctcatcaat
     8701 ggcatgctta taggcttcaa ggacaaagtc acgacctgca aaagcagaaa ctagcatgac
     8761 aagcgttgac ttgggcagat ggaagttcgt tgaaaaagca tcaacaacct taaattggta
     8821 gcctggctta ataaaaatat tagtccaacc agaatctgct agaatttgcc cttggaattt
     8881 gctgccaatc gtttctagtg tgcgaataga agtagtacca acagcaataa tgcgtccacc
     8941 agcggcctta accttcctaa gggtttgggc ggcctcttca gatagcaggt agaattcaga
     9001 gtgcatgtca tgctcatcga tattatcgac agaaactggt ctaaaggttc ctaggccaac
     9061 atggagggtc aggtagacga ggtgtactcc tttggcttct attttttgca gaagttcctg
     9121 agtaaagtgt agtccggctg taggagcagc tgctgagcca ttttccttgg cgtaaacggt
     9181 ctggtagcgc tcagcgtctg ctagcttttc atggatatag ggcggaagag gcatttcgcc
     9241 tagagtctct aaaatctcta ggaaaatacc atcgtatgaa aactcaacga ttcgaccgcc
     9301 atgctctagc tcttgaatga cccttgcctt taggcgtcca tcaccaaagc tgatctgtgc
     9361 accggcttta agccgctttg cgggcttggc taaaacctcc cattggtctc cctgaatgtt
     9421 tttaagcagc aaaagctcaa catgcccatg tgtttccatt ttttcaccgt ataagcgggc
     9481 aggaaggacc cgagtattgt tcatgaccag tgcatctcct ggctctagtt gatcaatgat
     9541 atggtcaaag tggctatctg tcatggtgtg ctcttgatgg tcgataatca agagcttcga
     9601 gcgatccctt tgttcaagtg gtgtttgtgc aatcagctcc tctggtagct caaaatcaaa
     9661 atcgttggta ttcatcttaa ctcctttacc cttcttgtga ggctatttac aatcagccta
     9721 tttatcctta gagataaatc ctttctatta tatcacttgt ccctggctac gtcacctgtc
     9781 atggttatga gacacataga gatgattgat ggccttttac tccttattag ctagtgcttc
     9841 ttagctgacg acaggggata tgagattatg gcttgacaat aattggtata taccatataa
     9901 tagaatcaca aaaggtctat accaatcaaa aaggagaatc agatgaaaat tattcgtgta
     9961 caggatcagt tagagggtgg caaggttgct tttagcctat taaaggaaag cttggcaaaa
    10021 ggggctacaa ccttaggatt ggcaacaggc agcacaccga ttacctttta tcaggagctg
    10081 gttaatagtg atttagactg ttcagccttg accagtatca acttagacga atatgtcggg
    10141 ctgccggttg aaaatgatca gagctatgac tattttatgc gtgaccagct gtttaacgct
    10201 aagcccttta aggaaagctt tttaccaaac ggcttagctg atgacttaga ggcagaggtt
    10261 aagcgctatg atcaagttat cgcagagcac cctattgatt ttcagattct tggaattggg
    10321 cgcaatggtc atatcggctt taacgagcca ggaacctctt ttgcagaaaa gacgcatgtg
    10381 gtggatttgc aggcttcgac aattgaggct aatagtcgct tctttgctag tattgatgat
    10441 gtgccaaagc aggctatttc aatgggaatt gcttctatca tggcatcaaa aatgattgtc
    10501 ctattggcct ttggtaagga aaaggctgcc gctattaagg gcatggtatc aggtccagtt
    10561 actgaggctt tgccagcaag tgtattacag cagcacggta atgttgtggt tattattgat
    10621 gaggctgccg cttcagagct ggattagact attgctgatg gctaacagct agtctgctat
    10681 ccgttgtgct cttttgatac agtgtaggta tctggctaaa ggtttcttgc tgactttagc
    10741 aaaaaatctg atcagttatt aaaagaggct ctttggcctc ttttttagaa ttaaggtata
    10801 ttgtgataaa ctaatgctat gcgtttagat aaattattag aagtgacagg ctttggttct
    10861 agaaatcaag tgaaacaact catcaaagga aggtctgtct tgattgatgg gcaaccagct
    10921 agagctggtt gtcagagtgt tgattcaggt cttcaagtga taatggtaaa tggcaggcaa
    10981 ataaaggcat ttgctcatcg ctattacctg cttcataagc cagcaggggt tgtgtcagct
    11041 tgctctgata ggaagcacca aactgtcatt gatttgattc gtaaggagga tagagtggcc
    11101 aatctttacc ctataggccg cttagataga gatacaacag ggcttgtcct cttgacggat
    11161 aatggtccat tagggtttcg tatgcttcac ccgaagcacc atgtgaacaa gacctacctt
    11221 gtgactgtca atggctcttt ggctgctgat gcggtgcctt tctttgaaaa tggtgttacc
    11281 tttcttgatg gtactcgctg caagtctgcc gccttgcgga ttataaaggc tgatcaaatg
    11341 gagtcacaag cagaagtaac actctctgaa ggaaaatacc atcagatcaa gaaaatgttt
    11401 ttaagctatg gcttaaaggt cacacagctc aagcgaattg gttttgcaga aatagcgcta
    11461 ggggatttag ctgagggagc ttatcgtcag ctaacagtaa aagaaaaaaa gctcatcaag
    11521 acctatttaa cataaaatat tgttagattt gaagttgact gacaggttaa gtccagtgtt
    11581 tttcggatat atgctataga gagaacgata acaactggag acccctatgc taactgcctt
    11641 agaccaagat caaagagtca tctcgcttac agatggctct tccccctcac gcaagcaagc
    11701 ctttacctgt cctgcttgtg gagctgctgt acgcttgaaa aaaggaagaa ttatccgacc
    11761 ccactttgcc catattagcc taagtcattg ccaatacctg actgaaaatg aatcacatga
    11821 acatctcagg ctaaaggctg atctgtaccg tagcctatct cgctctgaga cagcagaggt
    11881 tgaggcctac ctgcctgatc taaatcaaat tgcagacctt ctggttaata agcacttagc
    11941 cttagaaatc cagtgtagtc agctaccaat caaaaggctg gagcaacgca gtagggctta
    12001 tcaggctaat ggctatcagg tgcgttggct cttaggaaga aagctttggc tgcaaaagcg
    12061 tctgacaggt ttacaaaggc aatgccttta tttttcttgg cagcttggct ttcatctttg
    12121 ggagctcgat gtggaacacc acctgatacg attgaaa
//
LOCUS       DARYXW010000063        11720 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.063, whole genome shotgun sequence.
ACCESSION   DARYXW010000063 DARYXW010000000
VERSION     DARYXW010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11720
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.063"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(756..842)
                     /locus_tag="TV191_001400"
     tRNA            complement(756..842)
                     /locus_tag="TV191_001400"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(806..808),aa:Ser,seq:gga)
     gene            complement(902..1537)
                     /gene="trmB"
                     /locus_tag="TV191_001401"
     CDS             complement(902..1537)
                     /gene="trmB"
                     /locus_tag="TV191_001401"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEL1507904.1"
                     /translation="MRVRKRKGAQEHLENNPHYVILEPEAAKGRWCEVFGNDHPIHIE
                     VGSGKGAFITGMALKNPEINYIGIDIQLSVLSYALDKVLASQAPNVRLLRVDGSSLTN
                     YFDAGEVDMMYLNFSDPWPKSRHEKRRLTYKSFLDTYKQILPENGEIHFKTDNRGLFE
                     YSLASFSQYGMTLKQVWLDLHASDYQGNVMTEYEARFAKKGQIIYRLEATF"
     gene            complement(1537..2328)
                     /locus_tag="TV191_001402"
     CDS             complement(1537..2328)
                     /locus_tag="TV191_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEL1507905.1"
                     /translation="MTTTEQDLVLTPLRGKSGKAYKGTYPNGESVFIKLNTTPILPAL
                     AKEQIAPQLLWAKRMGNGDMMSAQEWLNGRTLTREDMNSKQIVHILLRLHKSKQLVNQ
                     LLQLNYKIENPYDLLVDFEQNAPLQIQQNSYLQAIVKELKRSLPEFRSEVATIVHGDI
                     KHSNWVITTSGMIFLVDWDCVRLTDRMYDVAYLLSHYIPRSRWADWLSYYGYKNNDKV
                     MQKIIWYAQFSYLTQILRCFDKRDMEHVNQEIYALRKFREMFRKK"
     gene            complement(2391..3425)
                     /locus_tag="TV191_001403"
     CDS             complement(2391..3425)
                     /locus_tag="TV191_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1507906.1"
                     /translation="MKALFRKRRQEFQHKHTKYLPYVFNDHFVLVLLFLLGFILFQYS
                     QLLKHFPANPLPIQLGLLIAVLFLLNLGSVATYLEKADQHFLLTKEAEVIAHIRSAER
                     LSFILWSSLQTVLLLPLFPLFQRLGVSLLAFVLLLGVLVLAKRLLLKRKVASFLSSKG
                     LDWEKAIAFEADRQQAILKFYALFTNVKGISTKVKERPYLNPILKLIKADSKKVWTNL
                     YLRAFLRSSDYLGLWLRLLLLSCLSLAFISNPYLAVGLALVFHYLSLFQLLSLYHHYD
                     YHYMSGLYPTKPQHKQRNLLSLLRQLSGLMLIVNLVLCRSWQNALVLIVAMGLLNLLY
                     LPYKLKKMID"
     gene            complement(3429..4154)
                     /locus_tag="TV191_001404"
     CDS             complement(3429..4154)
                     /locus_tag="TV191_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019322154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1507907.1"
                     /translation="MLNIENVTGGYLNIPVLKDISFSVGNGELVGLIGLNGAGKSTTI
                     NEIIGFLKPYKGRISIDGLTLAEHEADYRKKIGFIPETPSLYEELTLAEHINTVAMAY
                     DIDVELAHKRAEPFLELFRLTDKLDWFPVHFSKGMKQKVMIICAFVIDPSLFILDEPF
                     LGLDPLAIADLIKALEVEKAKGKSILMSTHVLDSAEKMCDRFVILHQGQVRAQGTLAD
                     LQAVFGDASASLNDIYLALTKEG"
     gene            4691..5134
                     /locus_tag="TV191_001405"
     CDS             4691..5134
                     /locus_tag="TV191_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507908.1"
                     /translation="MNLSRFLTFGLVSLSALSISGLVQTEAKANEWQTIFEKPQEVVI
                     TDGWQTISEKPQEVSTANEWQVSSEEAQESVPDKFSQNEDPSLWAVPDKFSQNEDPSL
                     WAVPDKFSQNEDPSLWAVPDKFSQNEDPSLWAVPDKFSQNEDPSL"
     gene            5587..6006
                     /locus_tag="TV191_001406"
     CDS             5587..6006
                     /locus_tag="TV191_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003108095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEL1507909.1"
                     /translation="MENCIFCSIISGEIPSSKVYEDEQVLAFLDISQTTAGHTLLIPK
                     KHVRNILAMDAETASQTFERLPKIARAIQKATGATAMNIINNNEELAGQTVFHAHVHL
                     VPRYSQEDGIAIQYTTHEPDFPALAALAQQISQEISQ"
     gene            6003..6299
                     /locus_tag="TV191_001407"
     CDS             6003..6299
                     /locus_tag="TV191_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HEL1507910.1"
                     /translation="MTLKTMTTIGLTSVLAYQVYRKRHQIKETLVAMQTSKKAIQADV
                     DRIKANLAIIQKEARTLQAAGTELAYKWQAFNQEAQAHLTEIQQRMSKYQQETP"
     gene            complement(6469..7731)
                     /locus_tag="TV191_001408"
     CDS             complement(6469..7731)
                     /locus_tag="TV191_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEL1507911.1"
                     /translation="MKIGKKIFLMLTAIVLLTLGAMGVYLTNAYTFSTGELSKTFKDF
                     ATSSKKSDAIQQTEPFSILLMGVDTGSSHRTSTWQGNSDSMILVTINPKTKKTTMTSL
                     ERDILITLSGPNDNEMNGAEAKLNAAYAAGGAQMAIMTVQDLLNITIDKYVQINMQGL
                     IDLVNAVGGITVTNEFDFPISIADNEPEYQATVAPGTHKINGEQALVYARMRYDDPEG
                     DYGRQKRQREVIQKVLKKILALNSISSYRKILSAVSGNMQTNIEISSRTIPNLLGYTD
                     ALKNIKTYQLKGEGATLSDGGSYQIVTSDHLLEIQNRIRAELGLEKLSQLKTTATVYE
                     NLYGSLKTQSTQDSSYYYNSGSLPAYTDSSTQYSTYSSETSSSSSYQDTTAGTQESGA
                     ANVTPSPQADSPAEQQSSGATTGTPAAP"
     gene            complement(7732..8259)
                     /locus_tag="TV191_001409"
     CDS             complement(7732..8259)
                     /locus_tag="TV191_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1507912.1"
                     /translation="MSEQVVTIEEAKASDASALITLIKEAADETDFITGTEDVIAATV
                     EVLECFLEASQESLTDICLLLKVGDILAGLLNIAGKAYRETSYVGDCFMLVLKPYRNH
                     GLGQLLMETTLDWARETKQLCALELEVQARNTCAYHIYEKYGFKIEGVKRKDVKSRNG
                     DYQDVYLMRKYLERE"
     gene            complement(8252..8695)
                     /gene="tsaE"
                     /locus_tag="TV191_001410"
     CDS             complement(8252..8695)
                     /gene="tsaE"
                     /locus_tag="TV191_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEL1507913.1"
                     /translation="MFYSKNENELIAYGQGIGRQLKAGDVLVLTGDLGAGKTTLTKGV
                     AKGLGIDQMIKSPTYTIAREYEGRLPLYHLDVYRIGDDPDSIDLDDFIFGGGVTVIEW
                     GELLAKGTLHDYLEILITKTETGRQVDYLAHGHRSEALLEELKHV"
     gene            complement(9061..10521)
                     /locus_tag="TV191_001411"
     CDS             complement(9061..10521)
                     /locus_tag="TV191_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEL1507914.1"
                     /translation="MEKFFKLKENGTTVSTELMAGVTTFFAMSYILFVNPSILSAAGM
                     PSQAVFLATIIAAAISTLIMGLFANVPYALAPGMGLNAFFTYTVVFSLGFSWQEALAI
                     VFLCGLFNIFITVTKLRKSIIKAIPVSLQHAIGGGIGVFVAYLGFKNANLITFSLSSA
                     EIVTVNGVEPAKATAETFANGVFSVNANGGVVPAISTFTDPSVLLAVFGLLLTAVLVL
                     KNVRGAILIGITVTTLAGIPIGVVDLSAVNFADNHISSAFAELGTTFLAAFGGMASLF
                     SDSSRLPLVLMTIFAFSLSDTFDTIGTFVGTGRRTGIFSEEDERALENSSGFSSKMDR
                     ALFADAIGTSIGALFGTSNTTTYVESAAGIAEGGRTGLTAVSTAVCFVLSVLLLPIVG
                     IVPAAATAPALIIVGVMMVSSFLDVDWSDFDVALPSFFAAFFMALCYSISYGVAGSFI
                     FYCLVKLVKGKTKEIHPILWGATFLFVLNFIILALL"
     gene            10780..11591
                     /locus_tag="TV191_001412"
                     /pseudo
     CDS             10780..11591
                     /locus_tag="TV191_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983364.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
BASE COUNT         3647 a         2645 c         2223 g         3205 t
ORIGIN      
        1 tatttttaaa gacagcatta gttaatgata taataaaagc tgtaatctcc ctcattatat
       61 cataaaaacg atttcaaaaa cagacttgta tttcaagtga catttgatat acttgaagat
      121 gggaatactg cttgagtgga ggcattgtag gtctagttca acgtaaagca gcagctgaaa
      181 tcgcaaaact aatacttaaa gtggggatca agaatgtagc ccctgctgca gctgcagcat
      241 cattaatttg gagctttgga agatgcatgt ggttttaatg tcaaaaagat atagtatttg
      301 tataacattt cttgttatta tttcgcgatt cgtttggttt gcccttacag gaagaagtcc
      361 tttttatgac tttattggga ctatattttt aggagtagtg gttttactaa ttagtcaaaa
      421 agtattgaaa aaattaaagt gataaaatta ttaacccgac aatagcgaag cagaatgtga
      481 tattattgat atgttccata agatactttc taatgagatt gttagtgctt ctcatgataa
      541 gtcttatggg acttttttgt actcaaaaag ccctatcatt tccatactgg ataaatccac
      601 tacagaaatg atagagccta aaatatatgt tcaccaattg gataagttaa aagaaaaaaa
      661 tgaccatcag gtcaaaagca tttttcaaaa tctcaaattt gacgggtgaa aaacaggcga
      721 agactccgaa acccttgata taccaatagg ataaaaggag aggaggggat tcgaaccccc
      781 gagccccgtt aaggactaca cgctttccaa gcgtgcgcac tcggccacta tgcgacctct
      841 ccaagtaaaa ggctgatcaa ctcaacctca gtagtgtatc atatttttgt caaaatagct
      901 actagaatgt tgcttctagg cggtaaataa tctgtccctt tttagcaaat ctagcctcat
      961 actcagtcat cacatttcct tgataatcac tagcatgtaa atccagccag acctgcttga
     1021 gggtcatacc gtactgtgaa aagctcgcta ggctatactc aaataagcca cgattatctg
     1081 ttttaaaatg aatttcacca ttttccggca aaatctgctt ataagtgtct aaaaaggatt
     1141 tgtaggttag tcgacgcttt tcatgcctgc ttttgggcca aggatctgaa aaattcaaat
     1201 acatcatatc aacctcaccg gcatcgaaat aattggtcag gcttgaccca tcaacccgca
     1261 agagcctaac attaggagcc tgagaggcta ggaccttatc taaagcatag cttagcactg
     1321 atagctgaat gtcaatgcca atatagttga tctctgggtt tttcaacgcc atacctgtga
     1381 taaaggctcc cttgcctgag ccaacctcaa tatggatcgg atgatcatta ccaaagacct
     1441 cacaccagcg ccccttagca gcctccggct ctaaaatgac atagtgagga ttgttttcca
     1501 agtgctcctg cgcacccttt cgttttctaa ctcgcattat ttctttctaa acatttctct
     1561 aaattttcta agagcgtaaa tctcttgatt gacatgctcc atatctctct tatcaaagca
     1621 ccttaaaatc tgagttagat aagagaattg agcataccaa ataatctttt gcatgacctt
     1681 atcattattt ttatagccat aataggatag ccagtctgcc catcgcgacc gaggaatata
     1741 gtggcttagc aaataagcca catcatacat tcgatctgtt aggcgcacac aatcccagtc
     1801 caccaaaaaa atcatgccac tggtggtaat cacccagttg ctatgcttga tatcaccatg
     1861 tacaatcgtg gccacctcag agcgaaattc aggtaggctg cgctttagct ccttgacgat
     1921 agcctgtaaa taagaattct gttgaatttg caaaggtgca ttttgctcaa agtctactaa
     1981 aaggtcataa ggattttcaa ttttatagtt gagctgaagc aattgattaa ccaactgctt
     2041 ggacttgtgg aggcgcagca gaatatggac gatttgctta ctgttcatat cctctctagt
     2101 cagagtacga ccattgagcc actcttgagc actcatcata tcgccattcc ccatacgctt
     2161 tgcccaaagc aattgtgggg caatctgttc ctttgctaag gcaggtagga ttggtgttgt
     2221 attaagcttg ataaagacgc tttcgccatt tggataggtc cctttgtagg ctttgccact
     2281 ttttccgcgc aagggagtca atacaagatc ctgttcggtt gttgtcacct tatcccctcc
     2341 ttttctatct tctgtaacca gttatcccta ttttacttgt tttaaaggac ttagtcaatc
     2401 atcttcttta acttgtacgg taagtaaaga agatttaata atcccatcgc cacaatcaac
     2461 acaagagcat tttgccaaga acggcagagc acaagattga cgataagcat caaaccactt
     2521 aattgcctca acaaagaaag tagattcctt tgcttatgct gtggtttagt cgggtaaagc
     2581 ccactcatat aatggtaatc ataatgatga taaagtgata ataactgaaa aagacttaga
     2641 taatgaaaga ccaaggccaa gcctactgct aaataagggt tggaaataaa ggcaagtgac
     2701 aagcaactaa gcaacaacag acgtaaccat aaccctagat aatcagagct gcgtaaaaat
     2761 gctcttaaat ataggtttgt ccaaaccttt ttactatctg ccttgataag cttaagtata
     2821 ggattcaagt aaggcctttc cttaaccttg gttgagattc ctttaacatt tgtaaacaaa
     2881 gcataaaact ttaaaatggc ctgctggcga tctgcctcaa aagcaatcgc tttttcccaa
     2941 tcaagcccct tggagctcaa aaagcttgcc accttacgct ttaacagtaa gcgcttagcc
     3001 agcaccaaaa caccaagcaa tagcacaaag gcaagcaagg aaacaccaag cctttgaaac
     3061 aaaggaaata aaggtaacag caagaccgtt tgaaggctag accaaagaat aaaggacaag
     3121 cgctctgctg acctgatatg ggcaataacc tctgcctcct tggtcagcaa aaaatgctga
     3181 tcagcctttt caagataggt agcaactgac cccagattaa gcaaaaacaa gacagcaatc
     3241 aacaaaccta gctgaatcgg tagaggatta gcaggaaaat gcttgagtag ttgactgtac
     3301 tgaaaaagaa taaagcccaa aagaaacagc aagacaagaa caaaatgatc attaaagaca
     3361 taaggcagat acttggtatg cttgtgctga aactcctgac gacgcttacg aaataatgcc
     3421 ttcatagctt acccctcttt tgtcagcgct aggtaaatgt cattaagact agctgaagca
     3481 tctccaaaga ctgcctgcaa atccgccaga gtcccttgtg cacgcacctg tccctgatgc
     3541 aatatcacaa aacggtcaca cattttttct gccgaatcca gcacatgggt actcattaga
     3601 attgacttgc cctttgcctt ttcaacctct aaagccttaa tcaaatcagc aattgctaag
     3661 gggtcaagcc ccaaaaaggg ctcatcaaga ataaaaagac tagggtcaat gacaaaagcg
     3721 caaataatca taaccttttg cttcattccc ttagaaaaat gcaccggaaa ccaatccagc
     3781 ttatccgtca aacgaaacag ctctaagaag ggctcagctc gcttatgtgc cagctccaca
     3841 tcaatatcat aggccatagc taccgtattg atatgctctg ctaaggtcag ctcctcatac
     3901 aggcttggtg tttctgggat aaagccaatt ttcttgcgat aatcagcttc atgctccgcc
     3961 aaggttaagc catcaatgga aatccttccc ttatatggct ttaaaaaccc aataatttca
     4021 ttaatcgttg ttgacttacc agcaccattt agaccaataa gccctactag ctctccattt
     4081 ccgacagaaa agctaatatc cttcaaaact ggaatattaa ggtagcctcc agtgacattc
     4141 tcaatgttta acatatcatt tctttctaat atctaatcta ttgtagcttt gcatactagc
     4201 ttccctagat gacaggttat tagcctagac agataggact tactaggcaa tgctttgtca
     4261 tcatcagcct atccagcgct ttgaagcact gataagacca attagcttga ccctacttaa
     4321 gaaagctggg gcagctaata ctaagggtac acttatatta gctattataa caaatttctg
     4381 cacagagcgt taactgtttt gatcaatgct cccatcagct aaaaacgctg agtgaatctg
     4441 aagtctattt taagatcatc aagaaaaagg cctagctata aaaacagagg ctatattagc
     4501 ttgatctatc agtcctaacc atctatcaca tcatattcga atgacctggt gatcctaaat
     4561 agcagctcat ctaaggcgtc atctaaaaaa tcatgataat attatcttat tgtattgaat
     4621 ttttaataat ataatgttat cgttaacatg taaataagtg ttgcgtcttt aatgacaaag
     4681 gaggtatgtt atgaatttgt cacgcttttt aacatttggt ttggtatcac tttcagcact
     4741 ttcaatttca ggcctagtcc aaacagaggc taaggctaac gaatggcaga ctatctttga
     4801 aaagccacag gaggtggtta tcacagatgg ctggcaaact atctctgaaa agcctcagga
     4861 agtaagcacg gctaacgaat ggcaggtcag ctctgaagaa gctcaagagt ctgttcctga
     4921 taaattctca caaaacgaag accctagcct atgggctgtt cctgataaat tctcacaaaa
     4981 cgaggaccct agcctatggg ccgttcctga taaattctca caaaacgagg accctagcct
     5041 atgggccgtt cctgataaat tctcacaaaa tgaggaccct agcctatggg ctgttcctga
     5101 taaattctcg caaaacgagg accctagcct gtagtaaagc catccgcact cgattgaaga
     5161 taaggcctat gttgctgacg cttcaatctt tttttgttct aaaagctttc tcagccttaa
     5221 ctgtcaagaa gttccagcac ctcatactct ctgaaactct tgtccttaca aatattgtgc
     5281 catgtcacta ccgtacgata gtgcgcaaat gcacaccttt gacggaccta gcttgcagca
     5341 agtagcaggc ttagttatgt gcttaaccat aattgcttag tccattatca tgattcaaaa
     5401 ggctttgcta gtcatgtggt cgataaccat tagcaccagc tataaacaat tgcaatatag
     5461 accagtacat gctaagataa ctatagtatg agatagctat ggtcactgag caactactga
     5521 tttcttattc taaaattatt caactactga tttgagccat tgctacgcag acgaaaggat
     5581 tatcacatgg aaaattgtat cttttgcagc attattagcg gtgagattcc ctcctccaag
     5641 gtttatgagg atgagcaggt actcgctttt ttggatattt cgcaaacaac agcgggtcat
     5701 accctcttga ttcctaaaaa gcatgtccga aatatcctag caatggacgc cgagacagct
     5761 agccagacct ttgaacgatt acctaaaatc gctcgcgcca ttcaaaaagc aacaggtgct
     5821 actgcaatga acattattaa taataatgaa gagctagctg gtcagactgt ttttcacgcg
     5881 catgtgcacc tcgttcctcg ctacagccaa gaagacggga tcgctattca gtatacaaca
     5941 catgagcctg acttcccagc cctagcagcc ttggcacaac aaattagtca ggagattagc
     6001 caatgactct aaaaacaatg accacaattg gtctcacatc cgttttagcc taccaagtgt
     6061 atcgtaaacg tcatcaaatc aaagaaactc tagtagccat gcaaacctct aagaaggcta
     6121 tccaggccga tgttgatagg attaaggcaa atctcgccat cattcaaaag gaggctcgaa
     6181 cgcttcaagc agcaggaaca gaattagcct acaaatggca ggcctttaac caagaagctc
     6241 aggcccatct gactgaaatc caacaacgta tgagcaagta ccagcaggaa accccataag
     6301 cctaagcaga ctaccaagcc tcaaggtgac aaaaaagggc tctatcgttt ctgtagtgga
     6361 caagtccgct atagggatta tgggctcttt ttgtatgtac aaaaaagacg aagaaatcac
     6421 tcacaggatc aagccttgat gagatttctt cgtttttttg gctgtaccct aaggcgctgc
     6481 tggcgtacca gtggttgcac cacttgattg ctgctctgct ggtgagtctg cttgagggct
     6541 aggagtcaca ttagctgctc ctgactcttg tgtaccagct gttgtgtcct gatagctgct
     6601 gctagaggac gtctctgagg aataggttga gtactgggta gatgagtctg tataggccgg
     6661 taggctacct gaattgtaat aatagctgct atcctgagta gactgagttt ttaacgagcc
     6721 ataaaggttt tcgtaaactg tggcagtcgt ttttagctga ctaagctttt caaggcctaa
     6781 ttcagcacga atgcgatttt ggatttctaa aagatgatct gaggtcacaa tttgatagga
     6841 gccgccatct gacaaggtcg ctccctcacc ctttagctga taggttttga tatttttaag
     6901 ggcgtctgta tagcctaaaa gattaggaat ggttcgtgat gatatttcaa tgttggtttg
     6961 catattacca ctaacagctg acaagatctt tcggtaggag ctgatactgt taagggcaag
     7021 aatctttttc agcacctttt gaataacctc gcgctgacgc ttctgccgac cgtagtctcc
     7081 ctctggatca tcatagcgca ttcgagcata gaccaaggcc tgctctccat ttatcttgtg
     7141 agttcctggt gcaacggtag cctgatactc aggctcatta tctgcaatag agataggaaa
     7201 gtcaaattca ttggtaacag taatgccacc aacagcatta accaaatcaa tgagcccttg
     7261 catgttaatc tgaacgtatt tgtcaatcgt gatattcagc aagtcctgaa cggtcatgat
     7321 agccatttgg gcaccaccag ctgcataagc agcattcagc ttagcttctg ctccattcat
     7381 ctcattatca tttggacctg acaaagtgat gagaatgtct ctttctaagc ttgtcatggt
     7441 tgtctttttg gtcttagggt taatcgtaac cagaatcata gaatcactat ttccttgcca
     7501 ggtagaggtt ctgtgagacg atcctgtgtc aactcccatc aatagaattg aaaagggctc
     7561 tgtctgttga atggcatcac tttttttgga ggacgttgca aaatccttaa aggtctttga
     7621 caattctcca gttgaaaagg tataggcatt ggttaggtaa actcccatag cccccaaggt
     7681 caacagcaca atagctgtca gcattaaaaa gatttttttt ccaattttca tctattcacg
     7741 ttccagatat ttacgcataa ggtaaacatc ctgatagtct ccatttcttg atttgacgtc
     7801 ctttcttttg acgccctcta ttttaaagcc atatttctca taaatatgat aggcacaagt
     7861 atttcgagcc tgaacctcca gctccaaagc acaaagctgc tttgtttctc tggcccaatc
     7921 aagggtagtc tccatcaaaa gctgtcctag gccatgattg cggtagggtt tcaagaccag
     7981 cataaagcaa tcgccaacat agctagtctc acgatatgct ttgccagcta tatttagcag
     8041 accagctaat atatctccca cctttagcaa aaggcaaata tctgtcaaag actcctgact
     8101 agcctctaga aaacactcaa gcacctctac ggtagcagct atgacgtcct cagtccctgt
     8161 gataaaatct gtctcatcag cagcttcttt aattagagtg atcaaagctg acgcatctga
     8221 ggccttggcc tcttcgattg tcaccacctg ctcagacatg cttaagctcc tcaagaagtg
     8281 cctctgatcg atgaccatgt gctagataat caacctgccg gcctgtttct gtttttgtta
     8341 ttaaaatttc aaggtagtca tgcagggttc ccttggctaa aagctcgccc cactcaatca
     8401 cagtaacccc accaccaaag ataaaatcat ctaaatcaat agagtccgga tcatcaccaa
     8461 tccgataaac atctaaatga tacaagggta gtcttccctc atattctcga gcgatagtat
     8521 aggttgggct tttaatcatc tgatcaatcc ccaaaccctt agcaaccccc ttggtcagcg
     8581 ttgttttacc agcacctaag tcaccagtca agacaagcac atctcctgcc tttagctgtc
     8641 taccaatgcc ttgcccgtaa gcgattaatt cattctcatt tttgctataa aacataaggc
     8701 tattataaca gaaaaaaaac ggtcttccaa gcctaagcca gcctgtcagc aaaatattct
     8761 aggctcgtca gtcctcatat aatgtcgtca aagctcaatc agctttaaca tctcataaat
     8821 caaaagagcc agcagcaaat cacatggacc taacatcatg gcattctgct gtgatagcca
     8881 gggctgaatg ctctagaaat caacccgcag ctctaaaacc ttaagactta gcctaaatat
     8941 aggactagga aaaggtggca atgcctatga gcttagaaag tccatagtcc cagtccaaac
     9001 ggtaatccct gtctttattg tcccagcaaa aaagaggcac ctaagtacct cattagtcgt
     9061 ttacaataac gctaaaatga taaaattcaa aacaaataag aaggttgctc cccaaagaat
     9121 cgggtgaatc tccttggttt tgcccttcac aagcttcacc aagcaataga aaataaagga
     9181 gccagccaca ccgtatgaaa tagagtagca aagtgccata aagaaagcag caaagaagga
     9241 cggtagggca acgtcaaagt cgctccaatc aacatcaagg aaggacgata ccatcataac
     9301 cccgacaatg attaaggctg gtgcagtcgc agcggctgga acaattccca cgatcggcag
     9361 cagtaaaaca gataagacaa agcagacagc agttgataca gctgttagac ctgtacgtcc
     9421 tccctctgca ataccagcag cagactcaac gtaggttgtg gtatttgagg tgccaaataa
     9481 agctccgatt gaagtaccaa tagcgtcagc aaagagcgca cggtccattt ttgagctaaa
     9541 gccagagctg ttttccaaag ctctctcatc ctcctcagag aaaatccctg ttcgacgacc
     9601 agtcccaaca aaagttccaa tcgtatcaaa ggtatcagat agactaaagg caaagatcgt
     9661 cattaaaaca agcggcaagc gacttgaatc actaaacagt gacgccatgc caccaaaggc
     9721 agccaagaat gttgtcccta attcagcaaa ggctgagctg atgtgattgt ctgcaaaatt
     9781 aacagcagaa agatcaacca ctccaatagg aataccggct aaagttgtaa ctgtaatacc
     9841 aattaggatg gctccacgaa cgttcttaag cacaagcact gctgttagca gcagaccaaa
     9901 aactgctagc aaaacactcg gatcggtgaa ggttgaaata gctggaacca caccaccatt
     9961 agcattaaca gagaagacgc cattagcaaa tgtttcagca gttgccttag ctggctcaac
    10021 accatttaca gtaacaatct cagcagatga tagcgaaaag gtgatcaggt tagcattttt
    10081 aaaacctaga taagcaacaa agactccaat acctccgcca atagcatgct gcaggcttac
    10141 tggaatagcc ttgataatgc tcttgcgaag ctttgtgaca gtgataaaga tattaaacag
    10201 accacaaaga aagacaatag ccaaggcctc ctgccaagaa aatcctaagc taaaaacaac
    10261 agtgtaagta aagaaagcat taagtcccat accaggagcc aatgcgtaag gcacattagc
    10321 aaacaaaccc atgatcaagg tagagatagc agctgcgatg atggtcgcta aaaacaccgc
    10381 ttgcgacggc atacccgctg cactcaaaat acttgggtta acaaataaga tatatgacat
    10441 cgcaaaaaaa gtcgtcacac cagccatcag ctctgttgaa accgtcgtgc cattttcttt
    10501 taacttaaaa aacttttcca tttgaatgga gtctccttat tgataggcaa aatcaaaaaa
    10561 gcccttatct catcagataa gctttttctc ttaaaaccaa atgattatta tcgtttttac
    10621 gaacgatata ttcatcgtaa cattttatcg ttctattttc aatagctttt ttcgtttatt
    10681 tgccatgatc gttcaaaatt taacagcctt tttttctatt aaccgtccaa gcagcaattt
    10741 tctcttccac tgatcctaaa atttgttata atctagtgta tgactaaaaa actaattgct
    10801 attgatttag acgggacttt attgcatcac gacaatacca tctctaccta tactcaaaaa
    10861 accattaagg ccgtccaagc taagggacat gaggtcatca tctcgacagg acgtccttat
    10921 cgtatggcta ttgactacta ccttcagcta gagctaaaga cacctatgat tagctttaat
    10981 ggctctttga cccacctacc tgagcaaaga tggaaatacg agcataatgt gactcttgat
    11041 aaggcatacc ttctcaaact cctagcagtg caggaggact tccagatgga ctttattgct
    11101 agtgagtacc gaaaagcctt ctacattacc atgaataggc ctgagagcat tgaccccaac
    11161 ctttttggtt tgaggccatc acaccagata tggctttaca gatcgacaaa atcacgcagg
    11221 atccaaatgc tcttctcatg caaacgcatc atgaggataa gtatgcccta gccaaggcca
    11281 tgcgcgcctt cttcaaggac gaaattgagg tggactcttg gggtggtccc ttaaatatcc
    11341 ttgagatgtc ccccaaaaac attaataagg cctatacctt aaaatacctg cttagcattt
    11401 acaacaagga gcctaaggat ttaatcgcct ttggtgatga gcataacgac acagaaatgc
    11461 tggcctttgc cggaaccggc tatgccatga aaaatgccag ccctgtgctg ctgccctttg
    11521 ccgaccagca gctagcttac tctaacgaag aggacggggt cgccagaaaa ctagaagagc
    11581 ttttcttgtg aaagcaaacg aaaccattgt ttttcagaaa acgatggttt tcttaatgcc
    11641 gtttccgtca attgatgaaa gaatttctaa tattttcgtt atttttcagc atattttctt
    11701 ttttatgcgg cataaaaatc
//
LOCUS       DARYXW010000064        11282 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.064, whole genome shotgun sequence.
ACCESSION   DARYXW010000064 DARYXW010000000
VERSION     DARYXW010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11282
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.064"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(72..2753)
                     /locus_tag="TV191_001413"
     CDS             complement(72..2753)
                     /locus_tag="TV191_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEL1507915.1"
                     /translation="MSKEQRHEAFYTQSEETVLAQLESSRKGLTSTEAQQRLAAYGRN
                     ELDEGEKRSLFMKFLDQFKDLMIIILVAAAFLSVVTEGMEGLTDAIIILAVVILNAAF
                     GVYQEGQAEAAIEALKSMSSPLARVRRDGHVIEVDSKELVPGDIVLLEAGDVVPADMR
                     LLEVNSLKIEEAALTGESVPVEKDLSREVSADAGIGDRVNMGYQNSNVTYGRGMGVVT
                     NTGMYTEVGHIAGMLANADETDTPLKQNLDNLSKILTYAILVIAAVTFAVGVFLRGQR
                     PLEGLMTSVALAVAAIPEGLPAIVTVVLSLGTQVLAKRNAIIRKLPAVETLGSTEIIA
                     SDKTGTLTMNQMTVEKVYTNGALQESSADIAFDNNTLRVMNFANDTKVDPAGKLIGDP
                     TETALVQFGLDHRFDVREALVSEPRVAELPFDSDRKLMSTIHKQADGRYFIAVKGAPD
                     QLLKRVTQIEENGDIRPITEADKQTILATNKDLAKQALRVLMMAYKYTEVIPVLETEV
                     VEAELIFSGLVGMIDPERPEAAQAVKVAKEAGIRPIMITGDHQDTAEAIAKRLGIIEE
                     DGVDHVFTGAELNELSDEAFQKVFRQYSVYARVSPEHKVRIVKAWQNEGKVVAMTGDG
                     VNDAPSLKTADIGIGMGITGTEVSKGASDMVLADDNFATIIVAVEEGRKVFSNIQKTI
                     QYLLSANMAEVFTIFLATLFGWDVLQPVHLLWINLVTDTLPAIALGVEPAEPGVMKHK
                     PRGRQSSFFDGGVKEAILYQGALQTILVLGVYGFALMFPEHTSYHDVHADALTMAYVT
                     LGLIQLVHAYNVKSVYQSIFTVGLFKNKLFNYSIPVAFVALMATVVVPGFNKFFHVTH
                     LTLTQWLVVIVGSLLMVVLVELVKAIQRSLGQDDKAI"
     gene            complement(3101..3487)
                     /locus_tag="TV191_001414"
     CDS             complement(3101..3487)
                     /locus_tag="TV191_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEL1507916.1"
                     /translation="MKIEINNKISYGQETELIKEIHTGDLRQKADATYLIYQNNNNER
                     VVIKFNAAELTMSRFSKPQSVMRFLANKKALIAIPTPVGIQQFLTDTSHFHLDHGQQT
                     VTLDYALLQPSTETAFAHYHLEIKWY"
     gene            3568..4869
                     /locus_tag="TV191_001415"
     CDS             3568..4869
                     /locus_tag="TV191_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEL1507917.1"
                     /translation="MNEKVFRDPVHNYIHVNHQLIYELINTKEFQRLRRIKQVPTTAF
                     TFHGAEHSRFSHCLGVYEIARRVTEIFEEKYADLWHKEESLVTMTAALLHDIGHGAYS
                     HTFETLFDTDHEAVTQDIITSPETEINAILTRYSPDFPDKVASVINHTYPNKQVVQLI
                     SSQIDCDRMDYLLRDSYFSAANYGQFDLMRILRVIRPVKDGIAFDLSGMHAVEDYIVS
                     RFQMYMQVYFHPASRAVELILQNLLKRAKALYPSQQDYFQKTAPGLIPFFEKSFTLAD
                     YLCLDDGVLNTYFQQWITSEDHILSDLSSRFINRKILKSVTFDQESQQDLERLRKLVE
                     SVGFDPDYYTGIHVNFDLPYDIYRPELENPRTQIEMIQKDGSRAELSQLSAIVKALTG
                     TSYGDRRFYFPKEMLELDDLFTSDKEAFISYISNGHFHFNN"
     gene            5094..5903
                     /gene="yidA"
                     /locus_tag="TV191_001416"
     CDS             5094..5903
                     /gene="yidA"
                     /locus_tag="TV191_001416"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEL1507918.1"
                     /translation="MSIKLVAIDIDGTLLTDDRRVTNDVFDAIQEAKAQGVHIVIATG
                     RPITGVISLLEQLQLNQKGDHVITFNGGLIQDTATGEEVVKELMTYDDYLDIEYLSRR
                     LGVHMHAITTEGIYTANRNIGKYTVREARLVDMPVFYRTPEEMADKEIVKMMMIDEPN
                     LLDEAIKQIPQAFYDTYNIVKSTPFYLELTPKTVSKGTAIGHLAKKLGIDMSQTMAIG
                     DAENDRAMLEAVANPVVMENGAPELKKLAKYITKSNNDSGVAHAIRKWVLN"
     gene            5903..7117
                     /locus_tag="TV191_001417"
     CDS             5903..7117
                     /locus_tag="TV191_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II:glycine glycyltransferase FemX"
                     /protein_id="HEL1507919.1"
                     /translation="MYTYKIGISAKEHDQFVLSHPQVNLLQSAHWAQVKDNWEHELIG
                     FYQDDKQVAAAACLIKRLPLGMTMIYIPRGPIMDYSDFELVNFVMTSLKAYGKSKRAL
                     MIKYDPSLFISQALIGEERKDNDFTLSIIDFLKTIGVEWTGRTKELEQTIQPRFQANI
                     YAKDFKLQSLSKKARQSIRTAQNKGVEIIIGSTELLEDFSALMKKTEERKHISLRGIS
                     YYDKLMTTYANQAYITMARLNLPKQKALIQQQLEEALSNQQAFTQHSKPGKVAENQNT
                     IKRLEKELAFLDKEIQAGKSLVPLAATLTLIYGQTSENLYAGMDNDFRQYQAALLTWY
                     HTAEEAFKRGCQWHNLGGVENQLDGGLFQFKARLNPAIEEFAGEFSIPVGPISKVAMI
                     AYNLRKKLRSNP"
     gene            7117..8352
                     /locus_tag="TV191_001418"
     CDS             7117..8352
                     /locus_tag="TV191_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HEL1507920.1"
                     /translation="MALDIIDKETFGSFCSQMKYKSFIQSIEMAELLQKRGYQTQYLA
                     ISDQKNIKIAAILYSIPMTGGLRMEINSGPVVADTTYTTAFYKALQDYAKQQGALELV
                     IKPYDTYQTFTSDGHPNDDEKPELIKTLTELNFTHDGLLTGYHNGEGDWHYVKDLSGL
                     TSANVINSFSKKGKALLKKAKTFGIKLHKLNRDELTQFKEITAATSSRRDYTDKSLSY
                     YQDFYDSFGDSCEFMVATLNFDDYLTNLEHSQDKLKQRISKLEADLVKKPKSEKKQNQ
                     LRELSSQFDTFQVRIAEAQELIVKYGKKDIPLAGSLFVYTPQEAVYLFSGSYPEFNRF
                     YAPALLQEHVMLRAIEKKISCYNFLGIMGEFDGSDGVLRFKQNFNGYITRKMGTFRYY
                     PKPFKYKAIQAIKTMLGRS"
     gene            complement(8561..9319)
                     /locus_tag="TV191_001419"
     CDS             complement(8561..9319)
                     /locus_tag="TV191_001419"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEL1507921.1"
                     /translation="MSRKPIIAGNWKMNKNPQEAKAFVKAVVSKLPSNDLVDVAVAAP
                     AVDLVTTIEAAKDSVLKVAAQNCYFENSGAYTGETSPKVLADMGADYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGLTPIICCGESLETYEAGKAVAFVGAQVSAALEGLSAEQV
                     ASLVLAYEPIWAIGTGKSATQEDAQSMCKAVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NIKEYMACPDVDGALVGGASLEADSFLALLDFVN"
     gene            complement(9585..10781)
                     /gene="tuf"
                     /locus_tag="TV191_001420"
     CDS             complement(9585..10781)
                     /gene="tuf"
                     /locus_tag="TV191_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEL1507922.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETATRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIIMELMDTVDSYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGTVRVNDEIEIVGIRDEIKKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGI
                     VSEIEA"
BASE COUNT         3388 a         2570 c         2249 g         3075 t
ORIGIN      
        1 ttatttttta actatgaacg tcagaccttt ttgttagttt gaaagtgttc ttatcttttt
       61 gctaatgacg cttaaatcgc tttgtcatct tgaccaagtg agcgctgaat agccttgaca
      121 agctcaacaa gcacaaccat caagagactt ccaacaataa caactagcca ttgtgtaagg
      181 gtcaaatgag tcacatgaaa gaatttgtta aagccaggga caacaactgt agccatcaag
      241 gcaacaaagg ctactgggat agaatagtta aataatttat tcttaaataa tccaactgta
      301 aagatagact gataaacgga cttaacatta taagcatgca ccagctgaat gagaccaagt
      361 gttacataag ccatcgttaa agcatcggca tgcacgtcat ggtagcttgt atgctctggg
      421 aacatcaagg caaagccata aacaccaagc actaggattg tctgaagggc accctgatac
      481 agaatagctt cttttacacc accgtcaaag aagcttgatt ggcgtccacg aggcttgtgc
      541 ttcatgacac caggctcagc aggctcaaca ccaagagcga tcgctggcag cgtatctgtt
      601 accagattaa tccaaagcag gtgaaccggc tgaagcacgt cccagccaaa taaggtagca
      661 agaaagatcg taaagacctc agccatgttg gcagaaagca ggtactgaat tgttttttga
      721 atgtttgaaa agaccttacg tccttcttca acggcaacaa taatagttgc aaagttatca
      781 tcggcaagga ccatatcaga agctccctta gaaacctctg tacctgtaat ccccatacca
      841 ataccaatat cagctgtttt aagagacggc gcatcattga caccatcacc agtcatagca
      901 acaaccttac cttcattttg ccaagcctta acgatacgaa ccttatgctc tggagataca
      961 cgcgcataaa cagaatattg tctaaagacc ttttggaagg cttcgtcaga cagctcattg
     1021 agctcagcac ccgtaaagac atggtcaaca ccatcttctt cgataatgcc aagacgcttg
     1081 gcaatagctt ccgctgtatc ctggtggtca ccagtaatca tgatcggacg aataccagcc
     1141 tccttagcca ccttaacagc ctgagccgct tcagggcgct ctgggtcaat catgccaaca
     1201 agccctgaga aaatcagctc tgcttcgacc acctctgttt caagtactgg aatcacttct
     1261 gtgtatttgt aagccatcat caagacacga agggcttgct tagccaagtc cttattagta
     1321 gccagaatcg tttgcttatc agcctctgta atcggacgaa tatctccatt ttcttcaatt
     1381 tgagtgacac gttttaacag ctggtcagga gcacccttaa cagcgatgaa gtatctgcca
     1441 tcagcttgct tgtgaatggt tgacatcagc ttacggtcag aatcaaatgg taattctgcc
     1501 acacgaggtt ctgaaacaag agcctcacgc acatcaaagc gatgatctaa gccaaattgc
     1561 accaaggcag tctctgtagg atcaccaatc agcttacctg ctggatcaac cttagtatca
     1621 ttggcaaaat tcatcacacg aagggtattg ttgtcaaagg caatatcagc tgatgactct
     1681 tgaagtgccc cgttagtata aaccttttca actgtcatct ggttcatggt caaggtacca
     1741 gttttatctg aggcgataat ttcagttgaa ccaagggttt cgaccgcagg caatttacgg
     1801 ataatagcgt tacgctttgc tagcacctgt gttccaagag aaagcacaac cgtaacaata
     1861 gctggaagcc cctctggaat ggcagcaacc gcaagcgcca ctgatgtcat caagccttca
     1921 agtgggcgct gaccacgtaa aaagacacca actgcaaagg tcacagctgc aatcacaaga
     1981 atagcatagg ttaaaatctt agatagattg tcaaggtttt gctttagcgg tgtgtctgtc
     2041 tcatcagcat tagccagcat gccagcgata tggcctacct cagtgtacat accggtgttt
     2101 gtgacaaccc ccataccgcg tccataggta acgtttgagt tttggtagcc catgttaaca
     2161 cgatcaccaa taccagcatc agcagaaacc tctcttgaca ggtccttttc aactggaact
     2221 gactcaccag taagagcagc ttcctcaatt tttaaggaat tgacctctaa caaacgcata
     2281 tcagctggca ccacatctcc tgcctctagc aggacaatgt cgccagggac aagctcttta
     2341 gagtcaacct caatcacatg accatcacga cgcacacgtg ctaagggact agacatggat
     2401 tttaaggcct caatcgctgc ctctgcctgc ccttcctgat aaaccccgaa ggctgcattt
     2461 aagataacaa cagctaaaat aatgatggca tctgtcaagc cctccatccc ttctgttacc
     2521 acagaaagaa aggccgctgc aaccaaaata ataatcatca aatccttaaa ctgatcaagg
     2581 aatttcatga acaggctgcg cttttcaccc tcgtcaagct cattacgccc ataagctgct
     2641 aggcgctgct gtgcctctgt actcgttagc cccttacgac tagactctaa ttgagctaat
     2701 actgtttctt cactttgcgt atagaacgct tcatgtcttt gttctttcga caaattggtc
     2761 cctccttggt ctttttatgc tttattcaac taaaaagacc tgtttatttt tcttaaacaa
     2821 gtctcgctgt ttcagattgt accggaaatc gaaattccgt attgacgaca caatcacggc
     2881 taaccgtctg ctactccctt gatatagtca ctattataat aaaatgatga ccaaaaaaca
     2941 agaaaaaaac aaggaaatat tttttaaaag ccccaaatca tctgatgatt ttcagagcaa
     3001 aggtaactga tgaccaagct tagactatca ttaccgagat acagacagca gacacaggct
     3061 gtcatcttag gagactaaca aaggacttcc tctgctgaga tcaataccac ttgatctcca
     3121 aatgataatg agcaaaggcc gtctcagtgc tgggctgtaa taaagcataa tctagggtca
     3181 ctgtctgctg gccatgatcc aagtgaaaat ggctcgtatc tgtcaaaaat tgctggatcc
     3241 ctacaggcgt cggaatagcg atcaaggctt ttttgttagc aagaaacctc atcacagact
     3301 gaggctttga aaagcgactc atcgttagct cagcagcatt gaacttaatc actacccttt
     3361 cgttgttatt attttgataa attagatagg tagcatctgc cttttgtctc aaatccccag
     3421 tatgaatctc cttgattagc tctgtttcct gaccatagct gatcttgtta ttaatttcaa
     3481 tcttcatgat atcttctttc tcttgagttt tgctcgtcta ttctaccaat ttctgaccat
     3541 tttcgcaatt tctgctataa tagaagcatg aatgaaaaag tatttcgtga ccctgttcac
     3601 aactatatcc acgttaatca tcagctcatt tacgagctaa tcaataccaa ggaatttcaa
     3661 cgactaaggc gaattaagca ggtgccaaca acagccttta cctttcatgg tgccgagcat
     3721 agccgctttt cacactgtct tggtgtctat gagattgctc gccgtgtcac agagattttt
     3781 gaagaaaagt atgcagacct ttggcataag gaggagagtc ttgtaaccat gactgctgcg
     3841 ctcctgcatg atattggcca tggtgcttac tcgcacacct ttgagaccct atttgatact
     3901 gatcacgaag ctgttactca agatatcatt accagtccag aaacggaaat taatgcgatt
     3961 ttgacgcgct actctcctga ttttcctgac aaggtagcta gtgttatcaa ccacacttac
     4021 cccaataaac aggtagtgca gctgatctct agtcaaatcg actgcgatcg catggattat
     4081 ctgctgcgcg actcttactt ttctgcggct aattatgggc aatttgacct aatgcgcatt
     4141 cttagggtta ttcgacctgt gaaagatggc atagcttttg atctcagcgg tatgcatgcc
     4201 gtagaggatt acattgtcag ccgctttcaa atgtatatgc aggtttattt tcaccctgcc
     4261 agtcgagccg tcgagctgat cctacaaaac ttgctgaagc gtgctaaggc tctctatcct
     4321 agccagcagg actatttcca aaagacagcc cctggtctca ttccattttt tgaaaaaagt
     4381 ttcacgcttg ctgattatct ttgcttagat gatggtgtgc tcaataccta tttccagcaa
     4441 tggattacta gtgaggacca tatcctgtca gacctgtcta gtcggtttat caatcgaaaa
     4501 attttaaaat ctgtcacctt tgaccaagaa tcacaacagg atttagagcg cttgcgaaag
     4561 cttgttgagt cagttggttt tgatcctgat tattatacag gtatccatgt caattttgac
     4621 cttccttatg atatttaccg tcctgagctg gaaaatccaa gaacccaaat tgaaatgatt
     4681 caaaaagatg gcagcagggc tgagctatcc cagctctctg cgattgtcaa agctctcaca
     4741 ggcacaagct atggtgatag acgcttttat ttcccaaagg aaatgttaga gcttgatgac
     4801 ctctttacat cagataagga agcctttatc agctatatct ctaacggaca ctttcatttt
     4861 aacaactaag gaccagccaa ggtccttttg gctttttcat cacgctctag atttaaaatg
     4921 gtatattacc cgataaggac agctagagct ctgacaagca caagccacca aacacagcag
     4981 agcctttaat attgccaaaa tctcttttgt tttcatgaca aaagaaccta tttttagtaa
     5041 gatagaaggt ggcaaatcat tgattacaaa tcagaacaac caaggagaat tccatgtcta
     5101 tcaaacttgt tgccattgat attgatggca ccttactcac tgacgatcga cgcgttacta
     5161 atgacgtttt tgatgccata caggaggcca aggcccaagg agtgcatatc gtcattgcta
     5221 cgggacgtcc cattactggg gtcatctcat tattagagca attgcaatta aatcaaaagg
     5281 gagatcatgt catcaccttc aatggtggac tgattcagga cactgcaacc ggtgaagagg
     5341 tggttaaaga gctgatgacc tacgatgatt acctcgacat agaatattta agccgcaggc
     5401 taggcgttca catgcatgcc atcacaacag agggcatcta tactgctaac cgaaatatcg
     5461 gcaaatacac tgtacgagaa gcaaggcttg tggacatgcc tgttttttat cgaacacctg
     5521 aggagatggc tgacaaagag atcgtcaaaa tgatgatgat tgatgagcca aaccttttag
     5581 atgaggccat caaacagatt cctcaagcct tctatgacac ctacaatatt gtcaaatcaa
     5641 caccttttta tctcgaatta acaccaaaaa ctgtcagcaa gggcactgct attggtcacc
     5701 ttgccaaaaa gcttggcatt gacatgtccc aaacgatggc aatcggcgat gctgaaaacg
     5761 atcgagccat gcttgaagcg gttgctaacc ctgttgtcat ggaaaatggg gctcccgagc
     5821 tgaaaaagct ggccaaatac atcaccaaat caaacaatga cagcggcgta gcgcatgcta
     5881 ttcggaagtg ggtattaaac taatgtatac atataaaatc ggaatttcag ctaaagagca
     5941 cgatcagttt gtcctatcac atcctcaggt caatctgctg caaagcgctc attgggctca
     6001 ggtaaaggat aactgggagc atgagctcat tggtttttac caggatgaca agcaagtcgc
     6061 tgctgctgct tgccttatca agagactccc cctaggcatg accatgattt acattcctcg
     6121 agggccgatt atggattatt ctgactttga gttggttaac ttcgtcatga ctagcctaaa
     6181 ggcttatggt aaatccaagc gagctctcat gattaaatac gatccttcct tgtttatcag
     6241 tcaggcctta ataggtgaag aaagaaagga caatgacttc accctctcca ttattgattt
     6301 tttaaagacc atcggtgttg aatggactgg caggaccaag gagcttgagc aaacgattca
     6361 gccccgcttt caggccaaca tttacgccaa ggactttaag ctccaaagct tatcaaaaaa
     6421 agccagacag tctatccgaa ctgctcaaaa taagggagtc gagattatta ttggctcaac
     6481 agagctactt gaagacttct cagcactgat gaaaaagact gaggagcgaa aacacatttc
     6541 tttgcgtggc atttcctatt atgacaaatt aatgaccact tacgctaatc aggcttacat
     6601 taccatggct agattgaacc ttcccaagca aaaagcgctc atacagcagc aattagagga
     6661 agccttgagc aatcagcagg cctttaccca gcacagtaag ccaggtaagg tcgcagaaaa
     6721 ccaaaatacc attaaaaggc ttgaaaagga attggctttt ctagataagg aaatacaagc
     6781 aggtaaaagc cttgtacctc tagcagctac cctgacactg atctatggac agacctctga
     6841 aaacctatac gcaggtatgg ataatgactt tcgccaatat caggcagccc tcttaacctg
     6901 gtatcatacc gcagaagagg cctttaagcg cggttgtcaa tggcacaatt tagggggcgt
     6961 tgaaaaccaa ttagatggtg ggctgtttca gtttaaagca agactaaacc cagctatcga
     7021 agaatttgca ggagaattca gcattccagt tggacctatc tcaaaggtgg ccatgatagc
     7081 ctacaatttg agaaaaaaac taaggagtaa cccttaatgg ctttagatat cattgacaaa
     7141 gaaacgtttg gctcattttg cagtcaaatg aagtataaat ccttcattca atctatagaa
     7201 atggcagagc tgctgcaaaa gcgtggttat cagacacaat accttgcaat cagtgaccag
     7261 aaaaacatta agattgcagc cattctctac agtataccaa tgaccggcgg cttacgcatg
     7321 gaaatcaact caggtccagt agtggctgat acgacctaca caacagcctt ttacaaagcc
     7381 ttacaggact atgccaagca gcagggagca cttgagctag tcatcaagcc ctacgatacc
     7441 tatcagacct ttaccagcga tggtcaccca aacgatgatg aaaagccaga gctgatcaag
     7501 accttgacag agctcaattt tacacatgat ggcctgctaa caggctacca taatggtgaa
     7561 ggagattggc attatgttaa agatttaagc ggattgacct ctgctaatgt catcaattcc
     7621 ttcagtaaaa agggcaaggc cctgctaaaa aaagccaaaa cctttggcat taagctacat
     7681 aagctcaatc gtgatgagct aacacaattc aaggaaatta ctgctgctac atctagtcga
     7741 agagattata ccgacaagtc tttatcttat tatcaggatt tctatgatag ctttggggat
     7801 agctgtgaat ttatggttgc aaccctcaat tttgatgact acctgaccaa tctagagcac
     7861 agtcaagaca agctaaagca gcgcattagc aaattagagg cagacctagt taaaaaacca
     7921 aaatcagaaa aaaaacaaaa tcaactacgg gaactctcca gccaatttga tacctttcaa
     7981 gttcggatag ctgaagcaca ggagttaatt gtcaagtatg gcaaaaagga cattcctcta
     8041 gctggtagtc tctttgttta caccccgcag gaggctgtct atctcttttc tggctcctat
     8101 ccagaattta acaggttcta cgcgccagcc ctattacagg aacatgtcat gctaagagcg
     8161 attgaaaaga aaatcagctg ctataatttt cttggtatca tgggcgaatt tgatggctct
     8221 gatggtgttt tacgctttaa gcaaaacttt aacggctata tcacacgaaa gatgggaacc
     8281 tttaggtatt atccaaagcc cttcaagtac aaagccatac aggccatcaa gacaatgctt
     8341 ggtcgcagct aagtcaagct agtggctaag cagcccttta agccttccaa tggctattga
     8401 ccacaataat aaatccttga ttgtcttact cagaacccct ttagtaaact ttccaaccta
     8461 aaaataaggt ataggtgatc ccatgctcaa gaaggctatc aagcaaacca aaagctcaag
     8521 gaattaaccc ttgagctttt tagctatatt ataattgtca ttagttgaca aaatcaagca
     8581 aggcaaggaa gctatctgct tctagtgatg caccaccgac aagagctccg tcaacatccg
     8641 gacaagccat gtactcctta atgttttcag gcttcacaga accaccatac tgtacacgaa
     8701 ccttgtctgc cacctcttga ccaaagtcag cagcaaccac atcgcgaaca gccttacaca
     8761 tgctttgagc atcttcttga gtggcagatt taccagtacc gatagcccag attggctcat
     8821 atgccaatac caatgaagca acctgctcag cagatagccc ctctagagcc gcagacacct
     8881 gtgcaccaac aaaggctact gccttgccag cctcataggt ctcaagagac tcaccgcagc
     8941 agataattgg tgttaagcca ttagcaaaga tggcttttgc ttttttatta atatcttcgt
     9001 ctgtttcgtg gaagtaatca cgacgctcag agtgaccaat caccacataa tcagctccca
     9061 tgtcagcaag aaccttagga gaggtttcgc ctgtataagc gcctgaattt tcaaaataac
     9121 agttttgcgc agcaacctta aggacagagt ccttagcagc ctcaattgta gtgaccaagt
     9181 caacagctgg tgctgctact gcaacgtcaa caagatcgtt tgaaggtaat ttgcttacta
     9241 ctgccttaac aaaggctttt gcctcttgag gatttttgtt cattttccag ttaccggcaa
     9301 taattggttt acgtgacatt tcacatacct cttctttttt tatttacatc tactattcta
     9361 gcacaatttc tatgctaata aaagaaaatg gctgactttt aggaatattt tcacaaagaa
     9421 aagagtattt tctgaaacca ttttcaaacg ataaggctta tcgattagct aagcagaccc
     9481 gctaagtcct catctttata aacagagcaa aaagagccct taaaacaagg gctctcacaa
     9541 ttaagctgtc tgactttaat cgttatctgg gaacttaatc aaaattaagc ttcgatttct
     9601 gaaacgatac ctgaaccaac agtacgtcca ccttcacgaa ttgagaatgt agtaccttgt
     9661 tctacggcga ttgggtggat caactcaacg tcaatagtca cgttatcacc aggcataacc
     9721 atttctgtac ctgctggaag ctcgattgaa cctgttacgt cagtagtacg gaagtagaat
     9781 tgtggacgat agttgttgaa gaatggtgtg tgacgtccac cttcttcttt agtaaggata
     9841 tatacttcac ctttaaattt agtgtgtggg ttgatagaac ctggcttagc aataacttga
     9901 ccacgttcga tttcatcacg ttgtacacca cgaagaagaa caccaacgtt gtcccctgca
     9961 agaccttcgt caagctgttt acggaacatt tcgacaccag taacaactgc ttttttgatc
    10021 tcgtctctga taccaacgat ttcgatttcg tcgttaacac gaacagtacc gcggtcgata
    10081 cgtcctgaag caacagtacc acgtccagtg attgagaata cgtcctcgac tggaagaagc
    10141 aatggcttgt ctgtgtcacg ttctggttct ggaatgtatg aatcaacagt atccatcaat
    10201 tccatgatga tatcttcgta tttgctgtcg ccttcaagag ccttaagcgc tgaaccttgg
    10261 ataactggaa ggtcatcacc tgggaaatca tattctgaaa gaaggtcacg aatttccatt
    10321 tcaacaagct caagcaattc ttcatcgtca acaaggtcaa ccttgttcat gaacacgata
    10381 aggtgcttaa caccaacctg acgtgaaaga aggatgtgct cacgagtttg tggcattggt
    10441 ccgtcagttg aagcaactac aaggatagct ccgtccattt gagcggcacc agtgatcatg
    10501 tttttaacgt agtccgcgtg tcctggtgcg tcgatgtgcg catagtgacg tgtagcagtt
    10561 tcgtactcaa cgtgtgcagt gttgatagtg attccgcgtt cgcgttcttc tggagcagca
    10621 tcgattgaag cgtagtcttt tggttggtta actgagcttg gtagacgacg tgcaagaaca
    10681 gttgtgattg cagctgttaa agtagtttta ccatggtcaa cgtgtccaat tgtaccaatg
    10741 ttaacgtggg gtttactacg atcgtatttt tcttttgcca ttttaggaaa agcctccaat
    10801 aaaatatatt ttatagatag acggtaggca atacagtcta actttacctt actattgtag
    10861 caaattataa ggaaattgca agcagtaagt gaggaacttt aacggattta tcgttatccc
    10921 tgatttcaac aaccctagca tacaaaaaag gaaagagttt tcgtcttctc ccaggcaatc
    10981 cgctctttac cgttttttgc ttttcaaggc tctaggcatt tgcatacttt tggaggagag
    11041 ttgaattgtt aagagataat gcattcggag atctataaat cataggcagg acataccgat
    11101 ccaaaactaa gatagtggag acttgatggt ccatgacaga cgcgcgaaac agctatttcc
    11161 gaatgataat atagatgaga gtagacactt tcaacgttct tcctatagta aaagctatgc
    11221 aaaatcctac atattcttga aatagctgaa cattgaaata caggaagctt tattttattg
    11281 ct
//
LOCUS       DARYXW010000065        10456 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.065, whole genome shotgun sequence.
ACCESSION   DARYXW010000065 DARYXW010000000
VERSION     DARYXW010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10456
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.065"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            40..1203
                     /locus_tag="TV191_001421"
     CDS             40..1203
                     /locus_tag="TV191_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL1507923.1"
                     /translation="MSQKLGKQLIRSVVTALAAIAFGIFPASETTNHITYAEVNSLTP
                     SVEWPLEQYPNYYSIEGKSNINTKDFPKLYTTTEKVYKKSGRSTKRVTVSDLQYAALD
                     GYGRSGAAYGIITKDMIAMSAGYREKWESNPEPSGWYTYHFKETGKLATEADYLHSKS
                     KIKRTSNNSYESIVLSNGKIRNGYLFDRSHLIADSLGGRPFRNNLITGTRTQNVGNND
                     RKGGMQYIENKVLNYINHNPQVHVYYKAVPIYSGSELLPRAVVVSALSSDGKIDETVR
                     VFNTVNGFTINYQYSGISHDKGMEASSESEAEDITDESTPVAEPADEEAMETEAAAND
                     TIVYVTSNGQSKVYWYNKDHLPEKVNLNKVVEMTEQEALNRGKHHSSLEKINQ"
     gene            complement(1326..3944)
                     /gene="alaS"
                     /locus_tag="TV191_001422"
     CDS             complement(1326..3944)
                     /gene="alaS"
                     /locus_tag="TV191_001422"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000811843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEL1507924.1"
                     /translation="MKQLTSAQIRQMWLDFWKSKGHSIEPSANLVPVNDPTLLWINSG
                     VATLKKYFDGSVIPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAIEWGFELLTSPEWFDFPKEKLYMTYYPDDKDSYNRWIALGVEPSHLIPLEENFWEI
                     GAGPSGPDTEIFFDRGEAYDPDHIGIRLLEEDIENDRYIEIWNIVLSQFNADPTIPRS
                     EYKELPNKNIDTGAGLERLVAVMQGAKTNFETDLFMPIIKEVEKLSGHTYDQDGDNMS
                     FKVIADHIRALSFAIGDGALPGNEGRGYVLRRLLRRAVMHGRRLGIHETFLYKLVATV
                     GHIMESYYPEILEKRDFIEKIIKREEETFARTIDAGSGHLDQLLAQLKEKGQDRLDGK
                     DIFKLYDTYGFPVELTEELAEDAGYKIDHEGFKAAMKEQQDRARAAAVKGGSMGMQNE
                     TLAGITEPSEFLYETETVASRLSVIIVDNERSEMVSEGQALLVFDQTPFYAEMGGQVA
                     DHGVIKNDKGDLVARVIDVQKAPNGQPLHTVEVLASLALDTVYTLAIDHKRRYAVEKN
                     HTATHLLHAALHKVIGEHATQAGSLNEEAFLRFDFTHFEAVTAQELRRIEEEVNEQIW
                     KALAITTTETDIETAKAMGAMALFGEKYGKTVRVVQIGDYSVELCGGTHLSNSSEIGL
                     FKIIKEEGIGSGTRRIIAVTGQQAFESFRKQEDILKEIAHTLKVPQIEQLPSKVVSLS
                     EQLRDLQKEMAELKEKAAAAQAGDVFKKVQEANGLRYIASEVSVSDAGVLRTFADNWK
                     QRDYSDVLVLAASIGEKVNVLVASKDKRAHAGNLIKALAPIVSGRGGGKPDMAMAGGS
                     DASKLSELLAAVPEHL"
     gene            complement(4300..5301)
                     /gene="prsA"
                     /locus_tag="TV191_001423"
     CDS             complement(4300..5301)
                     /gene="prsA"
                     /locus_tag="TV191_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEL1507925.1"
                     /translation="MKKSTKLLAGIVTLASAMTLAACQSTNDNTSVITMKGDTISVSD
                     FYNETKNTEISQRAMLNLVVSRVFEDQYGKKVSKKRTEEAYNKSAEQYGASFSAALAQ
                     SGLTTDTYKRQIRSAMLVEYAVKEAAKKELTDADYKKAYESYTPEMTTQVTTLDNEET
                     AKAVLGEVKAEGADFAAIAKEKTTAADKKVDYKFDSGDTKLPADVIKAASGLKEGDIS
                     EVVSVLDPATYQNKFYIVKVTKKAEKASDWKKYKKRLKEIVLAEKTQNIDFQNKVIAK
                     ALDKANVKIKDQAFANILAQYANTDKKASKANTSKSDQKSSSDSSKDSQSSKSKSEK"
     gene            complement(5364..6071)
                     /locus_tag="TV191_001424"
     CDS             complement(5364..6071)
                     /locus_tag="TV191_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEL1507926.1"
                     /translation="MVKSYSKNANHNMRRSIVKEDIVHYMRTQLKQNEGFLAELEAFA
                     RQENIPIIQHEVVAYFRLLLQSLQPKRILEIGTAIGFSALLMAENAPEAEIITIDRNA
                     EMIGFAKENFAKYDSRKQITLLEGDAADLLAGLTGEFDFVFMDSAKSKYIQFLPEVLK
                     HLKIGGMVVLDDVFQGGDIAKPIKEVRRGQRTIYRGLQDLFAATLDNPGLTASLLPLS
                     DGLLMIRKNQADIRLLD"
     gene            complement(6154..6792)
                     /locus_tag="TV191_001425"
     CDS             complement(6154..6792)
                     /locus_tag="TV191_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEL1507927.1"
                     /translation="MKTSLIFDMDGVIVDSEYIFLSTKTQMLLDRGIDTNEAYQYQFM
                     GTTFDDMWTTMKKECQLEDSVEALIAEMNHRRQAMLERDGVKAIAGAAQLIKHLHAKG
                     YRLAVASSSPKADIIRNLTALGLLDCFEVLVSGEEVARSKPAPDIFLKAAEWLSVDPK
                     TCLVIEDSKHGSQAAKAAQMTCIGFANPDYPLQDLSACDSIVKQLKAVCELL"
     gene            complement(6842..7474)
                     /locus_tag="TV191_001426"
     CDS             complement(6842..7474)
                     /locus_tag="TV191_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEL1507928.1"
                     /translation="MTVNLIWDFDGTLVQSSEAIRQALGLLYQTYQLPFDEAWVMDTI
                     IQESIGQLLKRLAEAHQLDFSELLAFFTREQEARDHLIALMPTAKETLALTSQQGVKP
                     FIVTHKGRTTQAVLQRLGIADYFTEVITADCGFKRKPDPEALLFLIHHYQMDKSQTYY
                     IGDRPLDLAAARAAGISSINLLLPDSDDNHHISQLSDIVELFSGKNSSSN"
     gene            complement(7464..8021)
                     /locus_tag="TV191_001427"
     CDS             complement(7464..8021)
                     /locus_tag="TV191_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1507929.1"
                     /translation="MKEIRTIALADQAAFKRFQDILLAEKASGNTFVETKKVEDFAAF
                     VEQSRRFEVQTDHPDWSTSTNYYYFLDGQLVARIGCRWQLEKGDLATIGGHIGYVTRT
                     DYRGRGIMTDLLAFALQQYQERGIKRVLITANKDNIASRKTIEKAGGILEDIVQVADD
                     YPTTSLAGQAIARYWIDLRGKDCDS"
     gene            complement(8220..10022)
                     /gene="pepF"
                     /locus_tag="TV191_001428"
     CDS             complement(8220..10022)
                     /gene="pepF"
                     /locus_tag="TV191_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEL1507930.1"
                     /translation="MTDNRSHLEEKYTWDLSTIFATDAAWETEADSLLAAIEAARQQA
                     GHLLDSSSSLLDITELHLELARRVEKVYVYASMKNDQDTTVAKYQEYQAKASGIYAKF
                     SEAFSFYEPEFMALSQEAYQAFLAETPELTVYDHFFDKLFKTREHVLSQAEEELLAGA
                     QEIFNGAEETFSILDNADIAFPIVTNDKGEEVELTHGNFISLMESKDRKVRRAAYEAM
                     YSTYEQFQHTYAKTLQTNVKVQNYKARVHKYASARQAAMSANFIPEAVYDTLLENVNK
                     HLPLLHRYLKLRQEVLGLDDLKMYDVYTPLSETDLAIGYDEALEKAEKVLAVFGQDYS
                     ERVHRAFTERWIDVHVNKGKRSGAYSGGSYDTNAFMLLNWQDTLDNLYTLVHETGHSL
                     HSTFTRETQPYVYGDYSIFLAEIASTTNENIMTEALLHEVQDDKERFAILNHYLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSEYLNNLYADLNEKYYGLKKEDNHFIQYEWA
                     RIPHFYYNYYVYQYATGFAAASYLADKIVHGTQEDIDHYLTYLKSGNSDYPLEVIAKA
                     GVDMAKGDYLEAAFRVFEERLTELEDLVARGAHL"
     gene            complement(10012..>10456)
                     /locus_tag="TV191_001429"
     CDS             complement(10012..>10456)
                     /locus_tag="TV191_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEL1507931.1"
                     /translation="MIHEDLFGKVSYLVKTCSLDDDLLAFLRLPYQRKGLSAYQLQMD
                     KHLLRRIQKALLAKDSKWLKKQEEAYLAGDNLLDRPLEAYYPQVKPIACSAGFCQIHE
                     DLSHYYDCFEKYYAKAANKEVQKLFSPAYYVKMISNRNLGGPYDR"
BASE COUNT         2988 a         2450 c         2012 g         3006 t
ORIGIN      
        1 aaaatgaggg tgaaaaatta aataaaggag gacattgata tgtctcagaa gttgggaaaa
       61 caacttattc gctctgttgt tactgcctta gccgccatag catttggaat atttcctgca
      121 agcgagacga ctaatcatat cacctatgca gaggttaact ccttaacccc ttcggtagaa
      181 tggcctttag agcagtatcc taattactat agcatagaag gaaagtctaa tatcaacacc
      241 aaggattttc ctaagctata caccactacc gaaaaggttt acaaaaaaag tggtcgaagc
      301 actaagcgcg ttactgtttc tgatctgcaa tacgctgcac ttgatggcta tggccgttca
      361 ggagctgcct atggtattat cacaaaggat atgatcgcga tgtcagccgg ataccgcgaa
      421 aaatgggaaa gcaatcctga gccaagcggc tggtatacat atcatttcaa agaaactggc
      481 aagctagcta ctgaggccga ctaccttcac agcaaaagca agatcaaacg aacctcaaac
      541 aatagctatg aaagcatcgt ccttagcaac ggtaagattc gcaacggcta tctttttgat
      601 cgtagtcatt taattgctga cagcttaggt ggtcgtcctt ttagaaataa tctcatcaca
      661 ggtacacgta ctcaaaacgt tggcaacaac gaccgcaagg ggggtatgca gtacattgaa
      721 aacaaagtcc taaactatat taaccacaac cctcaggttc acgtttatta caaagccgta
      781 ccaatctact caggctctga attactccct agggccgttg tggtttcagc gctctcctct
      841 gatggtaaaa ttgatgaaac cgtaagagtc tttaacactg tcaatggctt taccatcaat
      901 taccaatata gcggcatcag ccatgataag ggcatggagg cttctagtga gtcagaagct
      961 gaggatatta cagacgaaag cactccagta gctgaaccag ctgatgagga ggctatggag
     1021 acagaggctg ctgctaacga cacaatagtc tatgttacaa gtaatggcca atcaaaggta
     1081 tactggtata ataaggacca tctgccagag aaggtcaatc tcaataaggt tgtagaaatg
     1141 accgagcagg aagccctaaa tcgaggaaag caccattcct ccttagaaaa aataaatcaa
     1201 tagtctcata acgactaaca caagagctgg ttgaagcaac cagctttttt tgtgtgatga
     1261 aggattagac agctccttag ctaaaagata aagaggctga taaagcactc aacctcttat
     1321 cgcttttata aatgctctgg tactgcggct aatagctctg atagcttgct tgcatcacta
     1381 ccacctgcca tcgccatatc tggcttaccg ccaccacgac ccgacacgat tggcgctaag
     1441 gccttaatca gattgccagc gtgagctctt ttatccttac ttgcaacaag aacattgacc
     1501 ttctcaccaa tgcttgcagc cagcacaagg acatctgaat aatctctttg cttccaatta
     1561 tcagcaaagg tacgcaagac tcctgcatct gatacggata cctcactagc aatgtaacgt
     1621 agaccgtttg cttcctggac ctttttaaag acatcaccag cctgagctgc tgctgctttt
     1681 tcttttagct ctgccatttc tttttgcaaa tcgcggagct gctcgctgag gctcacaacc
     1741 ttacttggaa gctgttctat ttgcggcacc ttaagcgtat gtgcaatttc ttttaggatg
     1801 tcttcttgct tgcggaagct ttcaaaggcc tgctgacctg tcactgctat gatacgacgt
     1861 gttcctgagc cgatcccctc ttccttgata atcttgaaaa gaccaatttc tgatgagttg
     1921 gacaagtgag tccctccaca aagctcaaca gaataatcgc caatctgaac aacacgaaca
     1981 gttttgccat atttttcacc aaagagggcc atagctccca tagcctttgc tgtttcaata
     2041 tcagtttctg tggttgtaat agctaatgcc ttccagattt gctcattgac ctcttcttca
     2101 atacgacgca gctcctgggc tgtaacggct tcaaagtgtg taaagtcaaa gcgtaaaaag
     2161 gcttcttcat ttaaggaacc tgcctgagtg gcatgttctc caataacctt gtgaagggca
     2221 gcatgaagca gatgagtagc ggtatggttt ttctcaacag catagcggcg cttgtgatca
     2281 atagcaagag tataaacagt gtctaatgca aggcttgcaa gaacctcaac agtgtgaaga
     2341 ggctgaccat tcggtgcttt ttgcacatct atcacacgag caacaaggtc acccttatca
     2401 tttttgataa ccccatgatc ggcaacctga ccacccattt cagcataaaa cggtgtctga
     2461 tcaaacacaa gcaaggcctg tccttctgaa accatctcac tacgctcatt atcaacgatg
     2521 ataactgata agcgagaggc aacagtctct gtttcgtaca aaaattctga tggctctgtg
     2581 atgcctgcca gtgtctcatt ttgcatgccc attgagccac ccttaacagc tgctgcacgg
     2641 gcacgatcct gctgctcctt catagctgcc ttgaagcctt catgatcaat cttatagcca
     2701 gcatcttctg ctaattcttc ggtcaattca actggaaagc cataggtatc atacagctta
     2761 aagatatcct tgccatcaag cctgtcttgc cccttttcct ttagctgcgc cagcaattga
     2821 tccaaatgcc ctgatcctgc atcaatggta cgtgcaaagg tttcctcctc acgcttgata
     2881 attttttcaa taaagtcacg cttctcaaga atctctggat aataggactc catgatatga
     2941 cctacagtag ctactagctt ataaaggaag gtctcatgaa taccgagcct acgaccatgc
     3001 ataacagcac gacgaagcaa gcgacgaagc acatagccac gaccttcatt accaggtagg
     3061 gcaccatctc caatcgcaaa tgacaaggca cgaatgtggt ctgcaatgac cttaaagctc
     3121 atgttgtcac catcttggtc gtaagtatgg ccagatagct tttccacttc cttgatgatc
     3181 ggcataaata ggtcggtttc aaagtttgtt tttgcgccct gcataacagc cacaagacgc
     3241 tctaagccag cacccgtatc aatgtttttg tttggaagct ccttgtactc tgagcgagga
     3301 attgtagggt ctgcgttaaa ttgagacaaa acaatattcc aaatttcaat ataacggtcg
     3361 ttttcaatgt cctcttccag caatctaatc ccaatatgat caggatcata agcctcacca
     3421 cgatcaaaga aaatctctgt atcaggtcct gacgggcctg caccaatctc ccaaaaattt
     3481 tcctctaatg gaatcaaatg gcttggctca acgcccagag caatccaacg attgtaagag
     3541 tccttgtcat ctgggtagta ggtcatgtat aatttttcct ttggaaaatc gaaccattcc
     3601 ggacttgtta acaattcaaa gccccactca atcgcttcgt cgcgaaaata atctccgata
     3661 gaaaaattac caagcatttc aaacatagta tggtgacgag ctgtcttacc aacattttca
     3721 atatcgttag tgcggattga cttttgagcg ttggtaatac gaggattttc aggaatgact
     3781 gacccatcaa aatatttttt gagggtggcc acaccagagt taatccaaag cagggttggg
     3841 tcattgactg gcacaagatt ggccgaaggc tcaatagagt gaccttttga tttccaaaaa
     3901 tcaagccaca tttggcggat ttgggctgat gttaactgtt tcatgattaa gataccaaga
     3961 gcgattagag agactgggta tgattgtcct tagcataagt agcctgggga gacgatctct
     4021 actcgcattc agttcctttc gttgattttt tatgggatta ggctaaaagc catcaaaaca
     4081 aaacaagccc atatcacaga gggcgaaaac cgcggtacca cctctattca atgagcttgt
     4141 cattcttaat tacttatatc agataaaatc acattaagca gcatgcctat cagattatcc
     4201 gtaactcaca gcaaccgtca cttctctggg tcaaatcctt gataaacaat tcttaactaa
     4261 accagtataa agcttttttg agcattcgtc aatgaaaatc tatttttctg acttagattt
     4321 agaagattga ctatccttgc ttgagtctga agatgatttc tgatctgact tgcttgtgtt
     4381 cgccttgctt gcttttttat cagtattggc atactgtgcc aagatattag caaatgcttg
     4441 gtctttgatc ttaacatttg ccttgtctaa ggcctttgca atgaccttat tttggaaatc
     4501 aatgttttgt gtcttttcag ccaagacaat ttcttttaga cgtttcttat atttcttcca
     4561 atcagaagcc ttttcggctt ttttggttac cttaacaata tagaacttgt tttgataagt
     4621 agccggatct aagacagaaa ccacctctga aatatcaccc tcttttaatc ctgaggcggc
     4681 cttgatcaca tctgctggta acttagtgtc tcctgagtca aacttatagt ctaccttctt
     4741 gtctgctgct gttgtctttt ccttagcaat agcagcaaag tcagcaccct cagccttaac
     4801 ctcacctaaa acagcctttg ctgtttcttc attgtctaga gtagtgacct gagtagtcat
     4861 ttctggtgtg tatgactcat aggctttttt gtaatcagca tctgtcagct cttttttagc
     4921 tgcttcttta acagcatatt caaccagcat ggctgagcga atttgacgct tgtaggtatc
     4981 tgttgtcaag ccagactgcg caagggctgc agagaatgac gcaccgtatt gctcagctga
     5041 tttattgtaa gcttcttccg ttcttttctt agaaaccttt ttaccgtatt ggtcctcaaa
     5101 aacacgacta accacaaggt ttagcattgc tctttgagaa atctctgtat tttttgtttc
     5161 attgtaaaaa tcactaacac tgatagtgtc gcccttcatc gtaatgacac ttgtattgtc
     5221 atttgtagac tgacaggctg ctagggtcat tgctgatgct agggttacga taccagcaag
     5281 taatttagtt gattttttca tgtgattttg tgctcctttt tgtcattaac cagtatatta
     5341 tatcacaatt tcttaaacgt aacttaatct aacaaacgaa tatctgcttg atttttacga
     5401 atcatcagca agccatcact aagcggcagc aggctggctg tcaatccagg attatcaaga
     5461 gttgctgcaa ataagtcctg aaggccacga taaatcgtgc gctgtcctct ccgaacctcc
     5521 ttgatcggct tagcaatgtc acccccctga aacacatcat ctaaaacaac cattccacct
     5581 atttttaagt gctttaacac ctctggaaga aactgaatgt attttgattt tgcagagtcc
     5641 ataaaaacaa agtcaaactc gccagtaagt cctgctaaaa gatcagccgc atctccttca
     5701 agaagggtaa tttgcttgcg gctatcgtat tttgcaaaat tttccttggc aaagccaatc
     5761 atctcagcat tgcgatcaat cgttataatc tctgcctcag gagcattttc tgccattagc
     5821 aaggcagaaa agccaatagc tgtgccaatt tctaaaatcc ttttgggctg caagctttgc
     5881 aataaaagcc tgaaataagc aacaacctca tgctggataa tgggaatatt ttcttgtctg
     5941 gcaaaggcct caagctctgc taaaaagcct tcgttttgct ttagctgcgt tcgcatgtag
     6001 tgaacaatgt cttctttgac aatagagcgg cgcatattat gatttgcatt tttactatat
     6061 gatttaacca tgctatccat tatataaaaa aactctaggt aatgctaggg ctttcactag
     6121 cctattcacc tttgacgatc tgagtagtat ctatcaaagg agctcacaga cagccttaag
     6181 ctgcttgaca atgctatcac aagcagacaa gtcctgtaag ggataatcag gattggcaaa
     6241 gccgatacag gtcatctgag cagccttagc agcctgacta ccatgcttac tatcctcaat
     6301 gacaaggcag gtcttgggat caacgcttaa ccattcagca gccttaagaa aaatatctgg
     6361 cgctggcttt gagcgagcaa cctcttcacc actaactaac acctcaaagc agtccaaaag
     6421 acctagtgca gtgagatttc taataatatc tgccttaggc gatgaggaag ctactgccaa
     6481 gcgatagccc ttcgcatgca ggtgcttgat taattgagca gcacctgcta tggccttgac
     6541 accgtcacgc tcaagcattg cttgacgacg atgattcatc tcagcgatga gggcttcaac
     6601 agaatcctct agctgacact cctttttcat agttgtccac atatcgtcaa aggtggttcc
     6661 cataaactgg tactgatacg cttcattggt atctatgcct cggtccaata gcatttgtgt
     6721 cttggttgac aaaaagatat attctgagtc aacaatcaca ccgtccatat caaaaataag
     6781 gcttgttttc atcatctacc tcctcttatg ctatatctca gtcaggtcaa gagcaagact
     6841 attaattact agagctattt ttaccagaaa aaagctcaac aatatctgac agctgactaa
     6901 tatgatgatt atcatcacta tctggcagca ataggttgat agagctaatc ccagctgccc
     6961 ttgctgcagc aaggtctaag ggcctatcac caatatagta ggtctgcgac ttatccatct
     7021 gataatgatg aatgagaaaa agaagcgctt cagggtccgg cttacgctta aagccacaat
     7081 ctgctgtaat cacctctgta aagtaatcag caatccccag acgctgcaaa acagcctgag
     7141 tggttcgtcc tttatgagtc acaataaaag gcttaacccc ctgctgagag gttaaggcta
     7201 atgtttcctt ggctgtaggc attagtgcta ttaggtgatc acgcgcttcc tgctctcggg
     7261 taaagaaggc cagcaattct gaaaaatcca gctgatgtgc ctctgctaac ctcttcaaaa
     7321 gctgtccgat ggattcttga ataatcgtat ccataaccca agcctcatca aagggcagct
     7381 gataggtctg atacaataaa cctagcgcct gacgaatagc ctcagaggat tggactagag
     7441 ttccatcaaa gtcccaaatg agattaactg tcacaatcct tacctcttaa atcaatccaa
     7501 taacgagcaa tagcctgccc tgctaagctt gtagtagggt aatcatctgc cacctgaaca
     7561 atatcctcta aaataccacc agccttttca atggtttttc gactggctat attatcttta
     7621 ttagctgtta ttaagacacg cttgatccca cgctcttgat attgctgtaa tgcaaaggcc
     7681 agcaagtctg tcataattcc acgcccgcga taatctgtcc ttgtcacata gccaatatgt
     7741 ccgccaattg ttgctaagtc tcctttttcc aactgccagc gacagcctat tctagccact
     7801 agctgaccat ctaaaaaata gtaataatta gtgctagtgg accagtcagg atgatcagtt
     7861 tggacctcaa accgtctaga ttgctcaaca aaggctgcaa agtcctctac ttttttggtc
     7921 tcaacaaagg tattacctga agctttttca gctaacagta tatcctgaaa gcgcttaaag
     7981 gctgcttgat cagctaaagc aattgttcta atctctttca tgcctggctc ctttttatta
     8041 tgctaaaaat caactgggca tttctcaagc attcatcatg ccaacgaaaa agagctgccc
     8101 ctagaactgt tgatgtaata ctacgtctag aggctgccca caggccttta agctaggctg
     8161 atagacactg actgctgcta tttaccaata gctcaaaacc taagaggaga tggcaactat
     8221 tagagatgtg cccctcttgc cactaagtcc tctagctctg tcaaacgctc ttcaaagacc
     8281 ctaaaggctg cttctaggta atcaccctta gccatatcaa caccagcctt ggcaatcacc
     8341 tcaagcggat aatctgaatt tccagacttc agataggtca agtagtgatc aatatcctct
     8401 tgagtaccat gcacgatctt atcagccaag tagctggctg cagcaaagcc tgttgcatat
     8461 tgatagacat agtagttgta atagaaatgc ggaatgcgag cccactcata ctggataaaa
     8521 tggttgtcct ctttttttaa gccataatat ttttcgttta aatcagcata gagattattg
     8581 aggtattcac ttgttaacac ctcgccattt tgatccgcct gatgaatagc gtgctcaaac
     8641 tcagcaaact gtgtttgacg aaaaaccgtt ccacgaaaac catctaggta atgattcaaa
     8701 atagcaaagc gctccttatc atcctgcacc tcatgtaaca aggcctcagt catgatattt
     8761 tcattagtgg ttgaagcaat ctcagctaag aaaatgctgt aatctccata cacgtaaggc
     8821 tgtgtttcac gcgtaaaggt tgagtgcagg ctatggcctg tctcatgcac tagcgtatag
     8881 aggttatcaa gcgtgtcctg ccaatttaag agcataaagg cattggtatc ataggaacca
     8941 ccagagtaag ctcctgagcg tttgccctta ttgacatgca catcaatcca acgctctgta
     9001 aaggcacgat gcacacgctc tgaataatcc tggccaaaaa cagccaaaac cttctctgct
     9061 ttttccaagg cctcatcata gccgatagca agatctgtct cagataaagg agtataaaca
     9121 tcatacatct ttagatcatc taaaccaagc acctcttgac gtagcttcaa ataacgatga
     9181 agcagcggca aatgcttatt aacgttttct agtagggtat cgtaaacagc ctctgggata
     9241 aagttggctg acatcgctgc ctgacgggct gaagcatatt tgtgaacacg tgccttataa
     9301 ttttgcacct ttacattggt ttgcagggtt ttagcatagg tgtgctggaa ttgctcataa
     9361 gtactataca tggcttcata ggcagcccta cgcaccttgc ggtctttcga ttccatcaag
     9421 ctaatgaaat taccatgtgt tagctcaacc tcttctccct tatcatttgt cacaatagga
     9481 aaagcaatgt cggcattatc taggatacta aaggtctcct cagcaccatt aaagatttct
     9541 tgtgcccctg ctaatagctc ctcctcagcc tgactaagga catgctcacg cgtcttgaac
     9601 aatttatcaa agaaatggtc atagactgtt agctccggtg tctcagctaa gaaggcttgg
     9661 taggcttcct gacttaaggc cataaattct ggctcataga atgaaaaggc ttcactaaat
     9721 ttagcataaa taccagaggc cttagcttga tattcttgat acttggcaac tgtcgtatcc
     9781 tgatcatttt tcatgctagc ataaacataa accttttcaa cacgacgagc cagctccaaa
     9841 tgcagctctg tgatatctaa gagactgctg cttgaatcca acaaatgccc agcctgctgc
     9901 cttgcagcct caattgctgc cagcagacta tctgcctctg tctcccaagc tgcgtctgtt
     9961 gcaaaaatag tgcttaaatc ccaagtgtac ttttcctcta gatgactacg attatctgtc
    10021 atacggacct cctaagtttc tattactaat cattttaaca taatatgctg gtgaaaaaag
    10081 cttttgcacc tctttatttg ctgcttttgc gtaatatttt tcaaagcaat cgtaatagtg
    10141 gctcaaatcc tcatgaatct ggcaaaagcc agctgagcaa gcaatcggct taacctgtgg
    10201 ataataagcc tctaggggcc tatcaagcag gttatcccca gctagataag cctcttcttg
    10261 ctttttcaac catttgctat cttttgctag taaggctttt tgaatccttc tcagcaagtg
    10321 cttatccatc tggagctgat aggctgacag gccttttctt tggtaaggca gccgcaaaaa
    10381 ggccaacaaa tcatcatcta aggaacaggt ctttactaga tagctgacct taccaaataa
    10441 atcctcatga atcata
//
LOCUS       DARYXW010000066        10424 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.066, whole genome shotgun sequence.
ACCESSION   DARYXW010000066 DARYXW010000000
VERSION     DARYXW010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10424
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.066"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(<1..1474)
                     /gene="rlmD"
                     /locus_tag="TV191_001430"
     CDS             complement(<1..1474)
                     /gene="rlmD"
                     /locus_tag="TV191_001430"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEL1507932.1"
                     /translation="MLSKNDIVQVEISDLSHDGLGIAKHEGFVFFVENALPGEIIQMR
                     VLKVNKNSGFGKVETYLTTSPMRQKKLDVTYLRTGIADLGHLLYPQQLLFKQKQVQDS
                     LYKIAGISNVEVKETIGMEYPYAYRNKAQVPVRRVNGQLETGFFRKHSHELVPISDFY
                     IQDKEIDRLIAFTRDLLRRFDIKPYDEKEQSGLIRHLVVRRGHYSGEIMLVLVTTRPK
                     IFRINQMIDSLVAEFPAITSILQNINDKPTNVIFGKAFTRLYGKETITDTILGNQYCI
                     SAQSFYQVNTTMAEKLYQTAIDFSELTADDVVIDAYSGIGTIGLSFAKEVKAVYGVEV
                     IEAAVRDAEKNAALNGITNAYYVADSAENAMANWCQEGIKPTVIIVDPPRKGLTESFI
                     KASAAMQPDKITYISCNPATMARDIKRYEELGYKLQKVQPVDLFPMTHHVETVALLSK
                     LNVDKYISVEIELDELDLTSAESKATYAKIKEYILEKFGFK"
     gene            complement(1552..2982)
                     /locus_tag="TV191_001431"
     CDS             complement(1552..2982)
                     /locus_tag="TV191_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEL1507933.1"
                     /translation="MTRYQKGGLSHHEELRYFYLLRNLNYLTETERREFTFLKSKMES
                     RAMPSRSQRSLTHYTRGGRDDYAQASQDNADAYDMSDEQQAGPNGLPLYPRSERRSKR
                     HQQKPILAPQQDFYDDPDQAIYEELAPEAMPKKGRRKKKKGRLRRFFRILFFLLLLLV
                     AGIAFMFFKGMMDVSTNKANYKPAVSQVFHGQDTSDGTNILILGSDQRITQGSTDART
                     DTIMVVNVGNKENKIKMVSFMRDTLVNIPGYSYNNQDSYDLKLNASFNLGEQENHQGA
                     EFVRQTLKHNFDIDIKYYVMVDFETFAEAIDTLFPDGVTIDAKFATVNGEAVAAVDVP
                     DDLRMKDGVVPNQTITVGEQKMDGRTLLNYARFRKDDEGDFGRTVRQQQVMAAIMSQI
                     KDPTKLFTGSAAIGKIYALTSTNVSFPFVLKNGVSVLTNGKNGVEHVTIPENGDWIDE
                     YDMYGGQALFIDFAKYQNRLSKLGLR"
     gene            complement(3181..3675)
                     /locus_tag="TV191_001432"
     CDS             complement(3181..3675)
                     /locus_tag="TV191_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEL1507934.1"
                     /translation="MTKLLLGFMGVGKTTVAAQLDEHFLDMDRLIEAKIGMSISAFFS
                     YRGEAAFRKLESDTLQEVLALDNETIVSTGGGVVLSKANRELIRKNHKNNILLTASFE
                     ALYDRLKKDRLCQRPLFLNHSEAELYAIFQQRMALYEGLADKVINVEHRTPKEVAAII
                     ANMS"
     gene            complement(3668..4951)
                     /gene="aroA"
                     /locus_tag="TV191_001433"
     CDS             complement(3668..4951)
                     /gene="aroA"
                     /locus_tag="TV191_001433"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEL1507935.1"
                     /translation="MKLKTKAKALRGRLRVPGDKSISHRAVIFGAIAEGQTVIHGLLR
                     GQDVLATIQAFRDLGVTIYESADSLIIEGRGFKGLKPAQKPLDMGNSGTSMRLLAGLL
                     AAQDFSVQLLGDDSLSRRPMDRITIPLSLMGAELSGQGEKELPPLIVKGCQELRPIHY
                     QLPVASAQVKSAILLAALQTQGETVILEKELTRNHTEEMIEQFGGKLSVAGKQISIKG
                     PQRLQGQTLQIPGDLSSAAFWLAAGLIVPGSDLVLENVGINPTRTGLLEVIEKMGGRI
                     SYQAVDKDRQAATLKVSYSTLKGIEISGDLIPRLIDELPVIALLATQAQGTTYIRDAQ
                     ELRVKETDRIQAVTDVLGQMGADIQATEDGMVTRGKTPLHGAAVSTCGDHRIGMMTAI
                     AALLVEEGQVTLERAEAILTSYPDFFKDLERLWHD"
     gene            complement(5084..6022)
                     /locus_tag="TV191_001434"
     CDS             complement(5084..6022)
                     /locus_tag="TV191_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEL1507936.1"
                     /translation="MSIKKFLDKVISKWQYEPIQAFMRHFQSAEMDLSAIAVAYYLIL
                     TAFPLIVIAANIFPYLNIDISDLLRLMKEQLPKDIYRSASSIVVNIFSKPSGSVLGVA
                     TLTGLWTMSRSLTSLQKAFNKAYDASEHRDFLLGHLVGLLTSLLILFLLTFALIFSTF
                     SKAAIQVLDRHYHLNDNITTLFLFLIQPITILIIFVGLMLLYFLLPNIKIKKIRYILP
                     GTFFTTFVMIFLSNMVGNYVVHNVERMVDIKTFGSVMIFIIMLWFIFLARILIMGAVF
                     NATYQELSIGKLEGRSGNVVSLIKKTLGNDGAPPKK"
     gene            complement(6024..6884)
                     /locus_tag="TV191_001435"
     CDS             complement(6024..6884)
                     /locus_tag="TV191_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEL1507937.1"
                     /translation="MITLKSAREIEAMDRAGDFLAGIHIGLRQIIKPGVDMWEVEEYV
                     RRRCKEDNVLPLQIGVDGQLMDYPYATCCGLNDEVAHAFPRHYILQEGDLLKVDMVLS
                     EPLDKAVVDVAALDFDNVAEMKKWTESYTGGLADSCWAYAVGTPSDEVKRLMDVTKEA
                     MYRGIEQAVVGNRIGDIGAAVQQYAESHGYGVVRDLVGHGVGPTMHEEPMVPNYGTAG
                     RGLRLKEGMVLTVEPMINTGTWEINTDMKTGWAHKTLDGGLSCQYEHQFVITKDGPVI
                     LTSQGEERTY"
     gene            complement(6901..8184)
                     /locus_tag="TV191_001436"
     CDS             complement(6901..8184)
                     /locus_tag="TV191_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEL1507938.1"
                     /translation="MSKHQDILDYLERLAIGKRVSVRSISNHLKVSDGTAYRAIKEAE
                     NRGIVETKPRSGTVRIEKKGRVRIDRLTYAEIARISDSEVLAGHAGLGHEFSKFSIGA
                     MTQQNIHRYLIKGGLLIVGDRENIQLLALKNHNAILVTGGFPVSKQVIETADSQGIPV
                     MVTHYDTFTVATMINHALSNIRIKTDLKTVAQVLIPVEEYGCLYETDTVEEFNALIKK
                     TGQVRFPIVDALDQVVGVVSMRDVVDQPAETRLEQVMSPNPITAKPNASLANISQKMI
                     FEDLNMLPVVDDHHFLLGIITRRQAMENLPNHQPGNLYTYSQQMLSSLEETLDYYQVM
                     IEPTMIDSAGNLSNGVVAEFLKEISVRVLTKKHQKNIIIEQMMIYFLHAVQIDDQLRI
                     YPKIITENRRSSTLDMEVMVDDQVIAKAIITTKLN"
     gene            complement(8177..8731)
                     /locus_tag="TV191_001437"
     CDS             complement(8177..8731)
                     /locus_tag="TV191_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1507939.1"
                     /translation="MDIWTQLARFAFVETQRLLLRPFQYADHQPFYDMISHNSHYQFV
                     FPESMTKAESDFLMVNAFMKEPLGVWLIEDKTSHSMLGSIRLEKYDKQQASAEIGYFL
                     AQPFWGQGLMTEVLKTLTFLAFQEFGLRQLIIVTHLENKASQRVAEKAGFRLTKQFKG
                     SDRHSHHIRDYLEYQLTIGEYHYE"
     gene            complement(9025..10314)
                     /locus_tag="TV191_001438"
     CDS             complement(9025..10314)
                     /locus_tag="TV191_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622582.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEL1507940.1"
                     /translation="MEKNKKVSYFLRQSAVGLASVSAAFLVGTTSVGALDAATVLEPT
                     TAFIREAVREINQLSDDYADNQELQAVLANAGVEALAADTVDQAKAALDKAKAAVAGV
                     QLDEARREAYRTINALSDQHKSDQKVQLALVAAAAKVADAASVDQVNAAINDAHTAIA
                     DITGAALLEAKEAAINELKQYGISDYYVTLINKAKTVEGVNALKAEILSALPSSEVID
                     AAELTPALTSYKLVIKGATFSGETATKAVDAAVAEQTFRDYANKNGVDGVWAYDAATK
                     TFTVTEQPVAETIEAAELTPALTTYRLVIKGVTFSGETATKAVDAATAEQTFRQYAND
                     NGVTGEWAYDAATKTFTVTEALEESPADPEKPSASLPLTPLTPATKTAPAKQKDKQKA
                     KTLPTTGEKANPFFTAAALAIMASAGALAVTSKRQQD"
BASE COUNT         2943 a         2513 c         1927 g         3041 t
ORIGIN      
        1 ctttaaaacc aaatttttct aatatatact ctttaatttt agcataggta gccttgcttt
       61 ctgcacttgt caaatcaagt tcatcaagct ctatttcaac acttatatac ttatcgacat
      121 taagtttgga caataatgct accgtctcga catgatgtgt cattggaaac aagtctactg
      181 gctggacttt ctggagttta tagccgagtt cctcgtagcg cttgatgtca cgcgccatgg
      241 tggcggggtt gcaggatata taggttattt tgtcaggctg catcgctgca ctggccttga
      301 taaagctctc agttagtccc tttcgtgggg ggtctacaat gataactgtt ggctttatgc
      361 cctcctgaca ccagtttgcc atcgcatttt cagcgctgtc agcgacatag taggcattgg
      421 taataccgtt tagcgctgca tttttctcgg catcacgcac tgctgcttcg atcacttcga
      481 caccgtatac tgctttgact tctttagcaa aggatagccc gatggttcca atgcctgaat
      541 aggcatcaat caccacatcg tcagcggtca attcagaaaa atcaatagct gtttgataga
      601 gcttttcagc cattgttgta ttgacctgat agaaggactg agcagaaata cagtattgat
      661 tgcccaagat cgtatctgtg attgtctctt ttccataaag ccttgtaaac gccttaccaa
      721 agataacatt agtaggcttg tcattgatat tttgcaggat agaagtaatc gctggaaatt
      781 ctgcgacaag gctatcaatc atctggttga tacgaaagat tttaggtcgt gttgtcacta
      841 aaaccagcat gatttctcct gaataatgcc cacgacgaac cacaagatga cgaatcaggc
      901 ctgactgctc cttttcgtca tagggcttga tgtcaaaacg gcgcaaaagg tcgcgtgtaa
      961 aggcaatcaa gcgatcaatt tccttatctt gaatgtaaaa atcagaaatc ggcactagct
     1021 catgagaatg cttacggaaa aaaccagtct ctagctgacc attgacacga cgaacaggaa
     1081 cctgggcttt atttcgataa gcataaggat attccatacc aattgtttct ttgacctcaa
     1141 cattgctaat ccctgcaatc ttatagagac tatcctgaac ctgcttttgc ttaaagagca
     1201 gctgctgcgg ataaagcaag tgccccaaat cagcaatacc tgtacgcaga taggtcacat
     1261 ccagcttttt ttgacgcatc ggtgaggttg ttagataggt ctctaccttg ccaaagccac
     1321 tgtttttatt gacctttagg acacgcatct gaatgatctc acctggaaga gcattttcaa
     1381 caaagaaaac aaagccttca tgcttagcga ttcctaagcc atcatggctt aaatcagaaa
     1441 tttccacctg aacaatatcg tttttactta acatttactt tccttttctt ttactacact
     1501 aatcactcaa aaaagaagag caaccatcgt tacccttcat tatagcatat cttagcgtaa
     1561 tcccagctta gataatcgat tttgatactt agcaaaatca ataaagagag cctgaccacc
     1621 atacatgtca tattcatcaa tccaatcccc attttcagga atcgtcacat gctccacacc
     1681 gtttttgcca ttagtcaaga cggacactcc atttttaagg acaaatggga aggagacatt
     1741 ggttgaggtt agggcataaa tcttaccaat agctgctgag cccgtaaaga gcttggttgg
     1801 atccttgatt tgagacatga tagcagccat cacctgctgc tgacgtacgg tccgaccaaa
     1861 atcaccctca tcgtcctttc ggaagcgagc atagttgagc agggtacgac catccatttt
     1921 ttgctcacca accgttatgg tttggttggg aaccactccg tctttcattc gtaaatcatc
     1981 tggtacatca acagcagcga ctgcttcgcc atttacagta gcaaatttgg catcaatggt
     2041 aacaccatct ggaaacagtg tgtcaatagc ctcagcaaag gtttcaaagt caaccatgac
     2101 ataatattta atgtcaatat caaaattatg cttgagtgtc tgacgcacaa attctgctcc
     2161 ttgatgattt tcctgctctc ctaaattaaa ggaggcgttc aattttaaat cataggaatc
     2221 ctgattatta tagctatagc caggaatatt aaccaaggta tccctcatga aggagaccat
     2281 tttgatttta ttctccttat tgccaacatt aaccaccatg attgtatctg ttcgagcatc
     2341 tgttgagcct tgcgtaatcc tctggtctga gcctagaatt aaaatattag tgccatcgct
     2401 agtatcctga ccatgaaaga cctgcgaaac tgctggctta taattggcct tgttagtaga
     2461 cacgtccatc attcccttga aaaacatgaa agctatccct gcaacaagca gcagcaacaa
     2521 gaaaaagagt attctgaaaa aacgtctcag acgtcccttc ttttttttcc ttctaccctt
     2581 tttaggcata gcctcaggcg caagctcctc atagatcgcc tgatctgggt catcatagaa
     2641 gtcctgctga ggggctagta ttggcttttg ctgatgcctt ttgctacgtc tttctgatct
     2701 tggataaaga ggcaggccat taggcccagc ctgctgctca tcactcatat cataagcatc
     2761 agcattatcc tgtgaagctt gagcataatc gtcacgccca cccctagtat aatgagtcaa
     2821 ggagcgctga gaacgagaag gcatagccct tgactccatc tttgacttta aaaaggtaaa
     2881 ttctctgcgt tcagtctcag tcaaataatt taaatttctt aataaataaa aatatcgtaa
     2941 ttcttcgtgg tggcttagac cacccttttg gtatctcgtc atgctcttcc aactcttagt
     3001 attctaatac aatttcttct attctttgtc taatgattct attataacct atattaacga
     3061 gattgtcctc taaaatcgtt agaattcaac tttatttcaa cctatatatt agcttttcat
     3121 acctaatcat taagaaaagc tgggctgcga ataggaggcc aaaagtctaa tcctcagcag
     3181 ttacgacata ttggcaatga ttgctgcaac ctcctttggt gttctatgct caacattaat
     3241 cactttgtct gccaatccct catacaaggc catgcgctgc tgaaaaatag catagagttc
     3301 tgcttcagaa tgatttaaaa acagtggtct ttggcatagc ctatcttttt taagccgatc
     3361 atacaaagcc tcaaaggagg ctgttaagag gatattattt ttgtgatttt ttctgattaa
     3421 ttctcggttt gccttactaa ggacaacacc tccaccagtt gatacgatag tctcattatc
     3481 aagtgccagc acttcctgta aggtatctga ctcaagcttt ctaaaggctg cttcaccacg
     3541 ataggaaaaa aatgctgata tgctcatgcc tattttagcc tcaataagcc tatccatatc
     3601 caaaaaatgc tcatctaatt gggctgcaac tgtcgtcttg ccaactccca taaatcctaa
     3661 tagcagctta gtcatgccat aacctctcta aatccttaaa aaagtcagga taagaagtca
     3721 ggatagcttc tgctcgctct agggtgacct gtccttcttc aaccagtagg gctgcaatag
     3781 ctgtcatcat gccaattcta tgatctccac aggtactgac agctgcacca tgtaatggtg
     3841 ttttgcctct agtcaccata ccgtcctctg tcgcctgaat atcagcaccc atctgtccta
     3901 atacatcagt aacagcctga atgcggtcag tttccttgac ccgtaattct tgagcgtccc
     3961 tgatataagt cgttccctgt gcctgagttg ccagcaaagc aataacaggc aattcgtcaa
     4021 tcaagcgagg aatcaagtca ccagaaatct caatgccctt tagggtggaa taagacactt
     4081 ttagggtagc agcctgcctg tccttatcaa cagcctgata ggagatacga ccacccattt
     4141 tttcaatgac ctctaaaaga cctgtccgcg taggattaat ccctacattt tcgagcacaa
     4201 gatctgaccc cggaacaatc agaccagcag ctaaccaaaa ggctgcgcta gagagatcgc
     4261 caggaatctg taaggtctgt ccctgcaaac gctgcggtcc tttgatactg atttgctttc
     4321 cagctactga gagctttcct ccaaattgtt caatcatctc ttcggtatga tttcttgtca
     4381 attccttttc aaggataaca gtctctccct gtgtctgcaa agcagctaat aaaatagcag
     4441 acttgacctg agcagacgct acaggcagct gataatggat cggccgcaac tcctgacagc
     4501 cctttacaat tagtggtgga agctcttttt ctccttgacc agatagctct gctcccatta
     4561 gagacaatgg tatggtaata cgatccatag gacgccttga taggctatca tctccaagca
     4621 gctgcaccga aaaatcctgt gctgctaata gccctgcaag caggcgcata gaagtacctg
     4681 aattgcccat gtctagaggc ttttgagctg gctttaggcc tttaaaacct cttccttcaa
     4741 tgattaaact atcagctgac tcgtaaatgg tgacacctag gtctcgaaag gcttgaatgg
     4801 tggctaaaac atcttgcccc cttaaaagac catgaatcac cgtttgcccc tctgctatag
     4861 caccaaaaat gactgcacga tggctaattg acttgtcacc tggtaccctt agacgtcccc
     4921 taagcgcctt agcttttgtt tttaatttca tcattactcc tatttttagt acaccagcat
     4981 tagctcagca aagcaaataa aagaaaatga agtaaggaca agggccctta ccccatcaac
     5041 taatcaccaa gcaccgtctt gtttttcatt ctaagacaag ccgctatttc ttgggcggcg
     5101 caccatcatt gcctaatgtc tttttgatga gagaaacaac attgccgctg cgcccctcta
     5161 atttgccgat ggatagctct tgataggtag cgttaaaaac cgcccccata atcaatatcc
     5221 ttgccaggaa aataaaccat agcatgatga taaaaatcat caccgaacca aaggttttaa
     5281 tatcgaccat tcgctccaca ttatgcacca cataattacc aaccatattg ctcaaaaaaa
     5341 tcatgacaaa ggtggtaaaa aatgttcctg gtaagatata cctgattttc ttgattttga
     5401 tatttggcaa caaaaaataa agcaacatca gaccaacaaa tataatcagt atcgtaatcg
     5461 gctgaatcag gaacaaaaag agcgtcgtga tgttatcatt taagtgataa tgcctatcca
     5521 gcacctgaat cgctgcctta gaaaaggttg aaaaaatcaa ggcaaaggtc aacaaaaaca
     5581 ggatcagcag gctcgtcagc aagcctacca aatgaccgag caaaaagtca cgatgctcag
     5641 aagcatcata agccttatta aaggcctttt gcagagaggt taggcttcgc gacattgtcc
     5701 aaagccccgt caaggtcgct actcccagca cactgcctga tggcttagaa aaaatattaa
     5761 ccacaatgga ggaggcagag cgataaatat ccttaggcag ctgctccttc attaagcgta
     5821 ataaatctga aatatcaata tttaaataag gaaaaatatt agccgcaatg acaatgagtg
     5881 gaaaggctgt caaaataagg taataagcaa ctgcaatcgc tgacaaatcc atctctgcac
     5941 tctgaaaatg gcgcataaag gcttggattg gctcatattg ccattttgat atgaccttgt
     6001 ccaagaattt ctttattgac attctaataa gttctttctt cgccctgact agttaaaatc
     6061 actggaccat cctttgtaat cacaaattga tgctcatact ggcaggacaa gccaccatca
     6121 agtgttttat gggcccagcc tgttttcata tctgtattaa tttcccatgt gccagtattg
     6181 atcatcggct ctacggtgag caccatgccc tccttcagac gtagtcctct tcctgctgta
     6241 ccatagttag gcaccatcgg ctcttcgtgc atggttggtc caacaccatg accaacaagg
     6301 tctcgaacca caccgtagcc atgactttca gcatattgct ggactgctgc accaatgtca
     6361 ccaatgcggt tccccacaac tgcctgctcg atcccacgat acatggcttc cttggtcacg
     6421 tccatcagcc ttttgacctc atcagacggt gtacctacag cataagccca gcaggaatca
     6481 gccaaaccac ctgtataaga ttctgtccac ttcttcattt ctgccacatt atcaaaatcc
     6541 aaggccgcta catcaacgac agccttatca agtggctcac ttagcaccat atctacctta
     6601 agcaaatccc cttcctgtag aatataatgg cgcggaaaag catgtgcaac ctcatcattt
     6661 agcccgcagc aggtagcgta aggataatcc attaattggc catcaacacc gatctgtaaa
     6721 ggaagcacat tgtcctcctt gcagcgcctg cgcacatatt cttcgacctc ccacatgtca
     6781 accccaggct taatgatctg tctgaggcca atgtgaatcc cagcaagaaa gtctcctgct
     6841 ctatccatag cttctatttc acgcgcagat tttaatgtta tcattgtttt tgtttctcct
     6901 ctaattaagc ttagttgtaa taatggcttt agcaatcacc tgatcatcaa ccatgacctc
     6961 catatcaagt gtactgcttc ttctattttc agttataatt ttagggtata tcctcaattg
     7021 atcatcaatt tggacagcat gtagaaagta tatcatcatt tgctcgataa tgatattttt
     7081 ttggtgtttt ttcgttagca ctctgacact gatttccttt aagaattcag caaccactcc
     7141 atttgacaga ttgccagcac tatcaatcat ggtaggctca atcatgacct gataataatc
     7201 caaggtctcc tcaaggcttg atagcatttg ctggctatag gtgtaaagat ttcccggctg
     7261 gtgattcggc aggttttcca tagcctgtcg tctggtaata atccccagca gaaaatgatg
     7321 atcatcaact actgggagca tgttcaaatc ctcaaagatc attttttgac taatattagc
     7381 caggctagca ttgggctttg cagtgatagg atttggagac atcacctgct caagtctagt
     7441 ctcagcaggc tgatccacca catcacgcat actgaccaca ccaaccacct gatcaagcgc
     7501 atctacaatt ggaaacctta cttgacctgt ctttttaatc agtgcattaa attcctcgac
     7561 agtgtctgtc tcataaaggc agccgtattc ttcaactgga atcagaacct gagcaactgt
     7621 ttttaaatca gtcttaatgc gaatattaga caaggcatgg ttaatcatcg ttgccactgt
     7681 aaaggtatcg taatgtgtca ccataaccgg aataccttgg ctatcagctg tttcaataac
     7741 ctgcttagac accggaaagc cacccgtcac taagatagca ttgtgatttt taagggctaa
     7801 cagttggata ttttcacgat cgccaacaat caaaagccct cctttgatca aataacggtg
     7861 aatattttgc tgggtcatcg ctccaataga aaacttgcta aactcatgtc ccaaaccagc
     7921 atgaccggct aaaacctcag aatcactgat ccttgcaatt tcggcatagg tcaaacggtc
     7981 aatacgaacc cgtccttttt tctcaatgcg gacagtacca ctacgcggct tggtctcaac
     8041 aatcccccga ttttcagcct ccttgatcgc tctataggca gtaccatcac taacctttaa
     8101 atgatttgaa atacttcgga cgctcacacg ctttccaata gcaagtcttt ctaaataatc
     8161 taaaatgtct tgatgcttac tcataatgat actcacctat cgttagttga tattctaaat
     8221 aatctcgtat gtgatgacta tgccgatcac tgcccttaaa ttgctttgtt aatcgaaagc
     8281 cggctttttc agcaaccctc tggctggcct tgttttccag atgtgtcaca atgatcagct
     8341 gcctcaagcc aaactcctga aaagctaaaa aggtaagcgt ctttaagacc tcggtcatta
     8401 agccctgtcc ccaaaagggc tgcgctaaaa aatagccaat ctcagcactt gcctgctgct
     8461 tatcatattt ttctagtcta atagagccaa gcatgctatg gctggtctta tcctctatta
     8521 accagactcc caagggctct ttcataaaag cattgaccat taagaaatca ctctcagcct
     8581 tggtcatgct ctctggaaac acaaactggt aatggctgtt atgactgatc atatcataaa
     8641 acggctgatg atctgcatat tgaaagggcc tcaagagcag tcgttgcgtc tcaacaaaag
     8701 caaaccttgc tagctgtgtc caaatatcca tagcctcccc ttcaacatgc ctgtaatact
     8761 attattatag cagatatcac ctaaacattc tataactgtc atgagttttg ccatgatgat
     8821 cataataacc tgacaagcca tatcatagct caatcagact ctaagctgtt aaactattac
     8881 taacagtcaa aaccaaaaaa gagaagaccg tctgatcttc tcttgctatc ttatctgcta
     8941 atgcttaaat gggctacatc atagaaaagt cctatgagta agctcatcct tctaaggcta
     9001 aacatgcttc cataaataca ctgcttagtc ctgctgacgc tttgaagtca ctgctaaagc
     9061 acctgcactc gccataatgg caagagccgc tgctgtaaag aatggattag ccttctcacc
     9121 agtcgttgga agagtcttag ccttttgctt atctttttgc ttagctggtg ctgtcttagt
     9181 tgctggtgta agcggtgtca acggaagaga agctgatggc ttttctggat cagctggact
     9241 ctcctctaaa gcctcagtga ctgtaaatgt ctttgtagca gcgtcataag cccattcacc
     9301 agtaacgcca ttgtcattgg catattgcct gaaggtctgc tcggctgtgg ctgcgtctac
     9361 tgccttggta gctgtttcac ctgagaaggt aaccccctta ataacaagcc tataggtggt
     9421 caaagctggt gttaattctg ccgcctcaat agtctcagct acaggctgtt cagtgactgt
     9481 aaatgtcttt gtggcagcat cataagccca aacgccgtct acaccatttt tattagcata
     9541 gtctctgaag gtctgctcag ctacagctgc gtctactgcc ttagtagctg tttcacctga
     9601 aaaagttgct cccttgatga caagcttata gctagtcaag gctggtgtta gttctgctgc
     9661 gtcaatgacc tcagaactcg gtagagctga taaaatctct gccttaagcg cattgacacc
     9721 ttcaacagtt ttggctttgt tgattaaggt cacatagtaa tcactaatgc catactgctt
     9781 tagttcattg atagcagctt ctttagcctc caacaaggct gctcctgtaa tgtccgcaat
     9841 agctgtatga gcatcattaa tggctgcatt cacttgatca actgaagcag catctgccac
     9901 cttagctgct gcagcaacta gagctagctg aaccttttga tcgcttttgt gctgatcact
     9961 taaggcattg attgttctgt aagcctcacg tcttgcttca tcaagctgaa caccagcaac
    10021 agctgccttt gctttgtcaa gagctgcttt agcctgatca acagtatctg cagcaagtgc
    10081 ctcaactcca gcattagcaa gaacagcctg aagctcttga ttgtcagcgt agtcatcact
    10141 cagctgattg atttccctaa cagcttctct aatgaaggct gttgtaggct ctaacactgt
    10201 tgctgcgtct aaagcaccca ctgaagtcgt tccaaccaga aaggctgccg acactgaagc
    10261 taaaccaaca gctgattgac gtaaaaagta ggataccttt ttgttttttt ccatttttcc
    10321 tccctcgctt tttgtaaaaa aaactttgac actaaaaact attaatgtca cttctattat
    10381 actacgccat tctttttaat caaccatttt atttaatttt tctg
//
LOCUS       DARYXW010000067        10294 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.067, whole genome shotgun sequence.
ACCESSION   DARYXW010000067 DARYXW010000000
VERSION     DARYXW010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10294
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.067"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            49..1860
                     /gene="glmS"
                     /locus_tag="TV191_001439"
     CDS             49..1860
                     /gene="glmS"
                     /locus_tag="TV191_001439"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019804802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEL1507941.1"
                     /translation="MCGIVGVVGSRNATDILMQGLEKLEYRGYDSAGIFVSDGRTSNL
                     VKSVGRIADLRSKIGIDVVGTTGIGHTRWATHGQATEENAHPHTSQTGRFVLVHNGVI
                     ENYLQMKEQYLAGHTFKGQTDTEIAVHLIGAFVEEGCSVLEAFKKALSIIEGSYAFAL
                     IDTEDMDTIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETSEFMEIHDKELVILTKDS
                     ARVTDYAGNPIDRQSYTAELDLSDIGKGTYPFYMLKEIDEQPTVMRRLISTYADAKGQ
                     MMIDPAIIRSVQEADRIYILAAGTSYHAGFASKSMLEHLTDTPVELGVASEWGYNMPL
                     LSKKPMFILLSQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREATYTMLLHAGP
                     EIAVASTKAYTAQVAALAFLAKAVGEANGKKEAISFDLVHELSLVAQSIEATLSDKEL
                     IAEKVQTLLATTRNAFYIGRGNDYYVAMEAALKLKEISYIQCEGFAAGELKHGTISLI
                     EDGTPVIGLISSSELVAAHTRGNIQEVAARGAHVLTVVEEGLEREGDDIIINKVHPFL
                     APIAMVIPTQLIAYYASLQRGLDVDKPRNLAKAVTVE"
     gene            2044..2379
                     /locus_tag="TV191_001440"
     CDS             2044..2379
                     /locus_tag="TV191_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEL1507942.1"
                     /translation="MTLPNCLQCDSEYVYEDGHLLICPMCSFEWTRGEEEPEEEGLVV
                     LDSNGTRLADGDTVTIIKDLKVKGAPKDLKQGTRVKHIRLVEGDHNIDCKIDGFGAMK
                     LKSEFVKKI"
     gene            2486..3127
                     /locus_tag="TV191_001441"
     CDS             2486..3127
                     /locus_tag="TV191_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL1507943.1"
                     /translation="MTYIMQVLPSLLDGALITLQVFFIVIVLSIPLGALLAFLMRVDF
                     KPLQWLLTLYIWVMRGTPLLLQLIFFYYVLPSVGVTFDRMPAAILAFTLNYAAYFAEI
                     FRGGIETIPNGQYEAAKVLKLSPVQTVRYVILPQVFKIVLPSVFNEVINLVKDSSLVY
                     VLGVGDLLLASKTAANRDATLAPMFIAGLIYLLLIGLVTILSKQVEKRFNYYQ"
     gene            3137..3766
                     /locus_tag="TV191_001442"
     CDS             3137..3766
                     /locus_tag="TV191_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1507944.1"
                     /translation="MLELNNISKRFGHKQIFDGFHLTVEDGEVLSLVGPSGGGKTTLL
                     RMLAGLEPIDSGNISYNGESVPIDHLEKRSLLGFVFQDFQLFPHLTVLDNLILSPTIT
                     MAMPRPDAKQKAMELLERLGLKEHAAAYPYALSGGQKQRVALARAMMIDPQIVGYDEP
                     TSALDSELRQEVEKLILQNREMGITQIVVTHDLQFAQTISDRIIKINPK"
     gene            3783..4619
                     /locus_tag="TV191_001443"
     CDS             3783..4619
                     /locus_tag="TV191_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1507945.1"
                     /translation="MTLKKTLLVALFAATATLLVACGASNKQTSSDAWDSYKQKKTIT
                     LGFDNTFVPMGYKDESGKNTGFDIELAKAVFDQYGINVKYQAINWDLKETELNNGKID
                     LIWNGYSVTKERQAKVAFTEPYMKNEQVLVTQKSSQISSFADMKNKTLGAQSGSSGYD
                     AFTSHPKVLKDLVKGNDATQYETFTQAFIDLKNKRIDGLLIDRVYANYYLQQEGELDR
                     YNIIASEFEGEDFAVGVRKADKTLQKKITQALKSLYQDGTFQKISKKWFGEDVATVQL
                     KS"
     gene            complement(4715..5953)
                     /locus_tag="TV191_001444"
     CDS             complement(4715..5953)
                     /locus_tag="TV191_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEL1507946.1"
                     /translation="MPNNPVENLRLAKRGPIVSIVTYLALSITKLLAGYLLNASSLIA
                     DGFNNLSDIVGNVTLLIGLHLASQPADANHRFGHWKIEDLSSLITSFIMFIVGFQVLL
                     QTIQQMISGKQSAIDPLGAIVGIASALVMLGVYAFNKALSKKVRSSALVAASKDNLSD
                     AVTSIGTSIAIIAASLKLPIIDRLAALIITFFILKTAFDIFMASAFSLSDGFDSTQLK
                     AYEKAILKIPKIIAVKSQRGRTYGSNVYLDIVLEMHPDLSVYESHAITEQVEQLLSEQ
                     FAVYDIDIHVEPAKLPKDDNCEYVYKKLYKNEKIMLSQIPDYQELIAKTFTFIDRDGQ
                     AYNAKQFLEQQRSSSNQLEAFCMQSISHNTKLVTYQLQGNQHTSIWRRHEAWHLIYHQ
                     ITPITNSIAIKKHYHIKRIS"
     gene            complement(6056..7390)
                     /locus_tag="TV191_001445"
     CDS             complement(6056..7390)
                     /locus_tag="TV191_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEL1507947.1"
                     /translation="MIAAAKWIDDLVWGAPLLLLLLGTGIYLTSRLSLLQVIKLPKAF
                     RLIFAKNEGQGDISSFAALATALAATVGTGNIVGVATAIKSGGPGALFWMWVAAFFGM
                     ATKYSEGVLAIKYRTKDANGQISGGPMYYILNGMGQKWRPLANLFAVSGILVALFGIG
                     TFAQVNAITSSLHHSLGISSPLISVLLAAVVAMIIFGGIQAIAKVAETVVPFMAIFYI
                     GASLTVIAVHYTKLLPMLVLIFKSAITPTAAIGGFAGSLVKDAIQKGIARGVFSNESG
                     LGSAPIAAAAAKTKEPVEQGLISMTGTFIDTIIICTLTGLAILVTGQWTSALEGAPLT
                     QSAFASIFGHMGTYALTLSLVLFAFTTILGWSYYGERCFIFLFGTTHLSYFRLIFVIM
                     VGLGGFLKLELIWILADIVNGLMALPNLIALLALSPVVIFETRAYFKRQSTK"
     regulatory      complement(7519..7605)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            7870..10161
                     /gene="pcrA"
                     /locus_tag="TV191_001446"
     CDS             7870..10161
                     /gene="pcrA"
                     /locus_tag="TV191_001446"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEL1507948.1"
                     /translation="MNPLLDGMNDKQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKYVNPWNILAITFTNKAAREMRERALALSPATKDTLIATFHSMCVRILRREADHI
                     GYNRNFTIVDPGEQRTLMKRIVKALNLDPKKWSERSILATISNAKNDLLDERAYELGA
                     SDLYSQTVARCYKAYQEELRRSEAMDFDDLIMMTLRLFDQNPDVLAYYQQRYQYIHVD
                     EYQDTNHAQYQLVTLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPDARVVL
                     LEENYRSTKKILQAANEVIQHNRHRRPKKLWTQNADGEQIVYYRANDERDEAVFVAST
                     ISNMCLELGKSFKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDVIA
                     YLTVVANPSDNLSFERIVNEPKRGVGPGTLDKLRQFAYGQGQSLLEAASSLEQSPLKG
                     KAAQAMLALASLLSDLRADLDQLSITALAEALLEKTGYLDMLRVQNTLESQARIENIE
                     EFLSVTKSFDDLSAQQQEHEAGIDRLGRFLNDLALIADSDDGNAETAEVTLMTLHAAK
                     GLEFPVVFLIGMEEGVFPLARAAEDQDELEEERRLAYVGITRAEECLFLTNANTRTLF
                     GKSSYNRPTRFLKEMSENLLSFQGLARPAHASFGVTFSQQGQRQFGTGMSLSEAIQSR
                     KSMAQPARAASTSTPLPFGPNAATSKQAVDWQIGDIAHHKKWGAGTVLEVKGSGKTME
                     LTISFPDVGLKKLLASVAPIEKK"
BASE COUNT         3000 a         1996 c         2400 g         2898 t
ORIGIN      
        1 attgatcatt aaagaaagta gtaagctagc ttactgaggt gttaagttat gtgtggaatt
       61 gttggagttg taggtagtcg taatgcgact gacatcttga tgcagggatt ggaaaaatta
      121 gagtatcgtg gttatgattc agctggtatt tttgtgtcag atggcaggac gtccaatttg
      181 gtaaaatctg ttggacgcat tgcagattta cgctctaaga ttggcattga tgttgttgga
      241 acgaccggta ttggtcatac acgttgggca acgcatggtc aagcaacaga ggaaaatgct
      301 caccctcata cctctcagac aggtcgcttt gttcttgttc ataatggtgt gattgaaaat
      361 tacctccaga tgaaggagca gtaccttgct ggacacacgt ttaaaggaca aacagacacc
      421 gaaattgcag ttcatttgat tggagcattt gttgaagaag gctgttcagt cttagaggct
      481 tttaaaaagg ctttatcaat cattgaaggc tcctatgcct ttgctttgat tgatacagag
      541 gatatggata cgatctatgt cgctaagaat aaatccccat tgctgattgg ccttggtgag
      601 ggctataaca tggtttgttc agacgctatg gccatgattc gtgaaaccag cgaatttatg
      661 gaaatccatg acaaggagct ggttatcctg acaaaggatt cagcaagggt gacagattat
      721 gctggcaatc cgattgatcg tcagtcatat acagcagagc ttgatctttc agatattggc
      781 aaggggacct atccatttta tatgctaaag gaaattgacg agcagccaac agtgatgcgt
      841 cgcttgattt caacctatgc agacgccaag ggacagatga tgattgatcc agctatcata
      901 aggtctgtcc aagaggctga tcgtatctat attcttgcag ctgggacctc ttatcatgct
      961 ggctttgctt ctaagtcaat gctggagcat ttgactgata cacctgttga attaggggtt
     1021 gcttctgagt ggggctacaa tatgccgcta ttgagcaaaa agccaatgtt tatcctcttg
     1081 agccagtccg gtgagacagc agatagccgt caggttttgg tcaaggcaaa tgagatgggg
     1141 attccaagcc taacagtgac aaatgttcct ggctcaaccc tatcacgtga agcaacctac
     1201 actatgctgc tccatgcagg tccagaaatt gcagttgcat caactaaagc ctacacagca
     1261 caggtcgctg cacttgcctt tctagctaag gcagttggtg aggctaatgg caagaaggaa
     1321 gctattagct ttgatttggt tcatgaattg tcattggtcg ctcagtctat tgaggccacc
     1381 ttatctgaca aggagctgat tgctgagaag gtgcagacct tattggcaac aacacgcaat
     1441 gcgttttaca ttggtcgtgg caatgattat tatgttgcta tggaggctgc actaaaatta
     1501 aaagaaattt catacattca gtgtgaaggg tttgcagctg gtgagctaaa gcatgggact
     1561 atttcactga ttgaggatgg cacacctgtt attggactta tttcttcaag tgagctggtt
     1621 gctgcacata cacgtggcaa tatccaagag gtggctgcac gtggcgctca tgtgttgaca
     1681 gttgttgagg agggcttaga gcgtgaggga gatgacatta ttattaataa ggtgcaccca
     1741 ttcttagcgc cgattgctat ggttattccg actcaattaa ttgcttacta tgcttccttg
     1801 cagcgtggtt tagatgtaga taagcctcgt aatttagcca aggctgttac agttgagtaa
     1861 tagttgcctg cttaaaatga ggcagcaggg tcctgaagcc tatttgaaac gagcttgaca
     1921 tgatgttatg tcaggctcgt tttttagtgc ttgcctggtc ttatgataac gtattcatct
     1981 tgtcaaataa gcatttctga agtaaaatat taacgttaag actaagaagc ttaggagagt
     2041 aagatgacgt taccaaattg tttacaatgc gattcagaat atgtttatga ggacgggcat
     2101 ttgctcattt gtccgatgtg ttcctttgaa tggacacgtg gtgaggagga gcctgaggag
     2161 gaggggcttg tcgttttaga tagtaatgga actagattag ctgatggaga cactgttacg
     2221 atcattaagg acctgaaggt caagggagcg ccgaaggatc tcaagcaggg aactcgtgtt
     2281 aagcatattc gtcttgttga aggtgatcac aatattgatt gtaagattga tggctttggt
     2341 gcaatgaagc taaaatcaga attcgtcaag aagatttaat aacaataagc aaccagatga
     2401 ctggttgtat ttttatagaa aagtactttt caatccatca gaaaatttgg tataatggat
     2461 aaactattta tatctaggag acaacatgac gtatattatg caggttttac ccagcttgct
     2521 ggatggtgcc ttaatcactt tacaggtttt ctttattgta attgtattat ccattccctt
     2581 aggggctctt ttagcttttt tgatgagggt tgactttaag cccttgcagt ggctattgac
     2641 gctctatatt tgggtcatga ggggaacacc cttattgtta cagctcatct ttttttatta
     2701 tgttttgcca agtgtgggtg ttacctttga tcgtatgccg gcagcgattt tggcttttac
     2761 cttaaactat gctgcttatt ttgccgagat ttttcgtggc gggatagaga ctattccaaa
     2821 tgggcaatat gaggctgcaa aggtgctgaa gcttagtccg gtacaaactg ttcgctatgt
     2881 tatcttgcct caggtgttca agattgtttt accaagtgtt ttcaatgagg tgattaactt
     2941 agttaaggat tcttccttgg tatatgtgtt aggagtaggg gatttgctat tagcaagcaa
     3001 gactgcggca aatagagatg caaccttagc accgatgttt attgcaggtt tgatttattt
     3061 gctcttaatt ggtttggtca ccattttatc gaagcaggtt gaaaaaagat ttaattatta
     3121 tcagtaaggg ggtcatatgt tagaactgaa caatatttca aagcgatttg gtcacaagca
     3181 gatctttgat ggctttcatt tgaccgttga agatggtgag gttttatctt tggtagggcc
     3241 atctggtggt ggcaagacta ctctgctccg aatgctggct ggcttagagc ctattgattc
     3301 gggaaatatt agctataatg gcgagtctgt tcctattgat catttagaaa aaagaagcct
     3361 gcttggtttt gtttttcagg atttccaatt gtttccacat ttgacggtgc tggataatct
     3421 catcttgtct cctaccatta ccatggctat gccaaggcct gatgcaaagc aaaaggctat
     3481 ggagctgctg gagcgcctag gtctcaaaga gcatgcagct gcttatcctt atgcgctatc
     3541 tggtgggcaa aagcaaagag ttgccttggc tagagcgatg atgattgacc cacagattgt
     3601 aggctatgat gagccgacaa gtgccttaga ctctgaatta cgtcaggagg ttgagaaatt
     3661 gattttgcaa aatcgtgaga tgggcattac ccagattgtt gtcacccatg atttgcagtt
     3721 tgctcagacc atttctgatc gtatcatcaa gatcaatcct aaatagaaga agaggtagtg
     3781 ctatgacgtt aaaaaagacc cttctagtag ccctatttgc tgctacagct acgcttttag
     3841 tagcttgtgg cgctagtaat aaacagacta gctcagatgc ttgggattcc tacaagcaga
     3901 aaaagacgat tacgcttggc tttgataata cttttgtgcc aatgggctat aaggacgagt
     3961 caggaaaaaa taccggcttt gatattgagc tagcaaaggc tgtttttgac caatatggta
     4021 tcaatgttaa gtatcaagcc attaactggg atctcaaaga aactgagttg aacaatggta
     4081 aaattgacct gatttggaat ggctattctg tgacaaaaga gcgccaagct aaggtggcct
     4141 ttacagagcc ttatatgaaa aatgagcaag tcttagtgac gcaaaaatca tcgcaaataa
     4201 gctcatttgc tgatatgaaa aataagacct taggtgccca gtctggctca tctggctatg
     4261 atgcctttac gagtcatcct aaggtgctaa aggatcttgt caagggaaat gacgctaccc
     4321 aatatgaaac ctttacacaa gcctttatcg atttaaaaaa caagcgtatt gatggccttt
     4381 tgattgatag ggtttatgcc aattattacc ttcagcaaga aggtgagcta gaccgctata
     4441 acattatcgc gagtgagttt gaaggtgagg attttgcagt tggtgtccga aaagcggata
     4501 aaaccctaca aaaaaagatt acacaagcct taaaatcgct ttatcaggac ggtaccttcc
     4561 aaaaaatctc taaaaaatgg tttggtgaag atgtcgcaac agttcagttg aaatcataag
     4621 acgcaagcaa gacctaatca gctcagaggg gttgagacta gatacattta aaagacttac
     4681 cttctaaagg caagtctttt tatacggctt attattagct gatacgcttg atatgatagt
     4741 gttttttaat tgctatggag tttgttattg gtgtgatttg atgatatatc aggtgccaag
     4801 cttcgtgtcg tctccagata ctggtatgct gattgccctg tagctgatag gtgactagct
     4861 tggtgttgtg gctgatggat tgcatacaaa aggcttcaag ctgattggaa gaagaacgct
     4921 gctgctctaa aaattgcttg gcattgtaag cttgtccatc gcgatcaata aaggtaaagg
     4981 tcttggcaat gagctcttga taatctggga tttgacttag catgattttc tcgtttttgt
     5041 agagcttttt gtaaacatat tcacagttgt catctttagg aagctttgca ggctcaacat
     5101 gaatatcaat atcataaaca gcaaattgct cactcaagag ctgttcgacc tgctcggtta
     5161 tggcgtgact ttcataaaca gaaaggtcag ggtgcatctc aaggacaata tctaaataga
     5221 cattgcttcc gtaagtgcgg ccgcgctgtg atttgacagc aatgattttg ggaattttca
     5281 atatggcctt ttcatatgct ttgagctgcg tgctgtcaaa gccatctgat aagctaaagg
     5341 cgcttgccat aaaaatatca aaggctgttt ttagaatgaa aaaggtaatg ataagggcag
     5401 ccagcctatc aataataggt agctttaagg aagcggcgat aatagcaata gaggttccaa
     5461 tagaggtcac agcatcagaa agattatctt tagaggctgc aaccaaggca ctggatctta
     5521 ccttttttga taacgcttta ttaaaagcat atactccaag catcacaagg gctgaagcga
     5581 tcccaacaat agcacctaat ggatcgatag cagactgctt accactaatc atctgttgaa
     5641 tagtttgcag gagaacctga aagccaacaa tgaacatgat aaaggaggtt attaagcttg
     5701 aaaggtcttc gattttccag tggccaaagc ggtgattggc gtctgctggc tggctggcca
     5761 gatgaagtcc gatgagcaga gtgacattac caacgatatc agacaggttg ttgaagccat
     5821 cggcaatcaa ggagctggca tttaaaagat agccagcaag aagctttgtg atgctaaggg
     5881 ccaaataggt aacaatgcta acaatgggcc ctctttttgc taaccgaagg ttttctactg
     5941 gattgtttgg cataaaaact cctttgtaac tgatgctttc attatatcat aaaagctaag
     6001 acaagctaaa agcctagagc tatcctaaat agggtattcc aggcttttcg atagcttatt
     6061 tggtgctttg gcgcttaaaa tatgcccttg tctcaaaaat gacaacagga gataaggcta
     6121 gtagggcgat aagatttggc agagccatca ggccattgac aatatctgcc agtatccaaa
     6181 tcaactccag cttaagaaag ccaccaagtc ctaccatgat aacaaagatc aggcgaaaat
     6241 agctgaggtg tgtcgtgcca aataaaaaga taaagcagcg ctcaccataa tagctccagc
     6301 cgagaatagt cgtaaaagca aaaagaacaa gcgacagggt caaggcatag gtgcccatat
     6361 gcccaaagat agaagcaaag gcagactgtg ttaagggtgc tccctctagt gcgctagtcc
     6421 actgaccagt taccaaaatg gccagaccag tcagagtgca gatgatgatc gtgtcaataa
     6481 aggttccggt catagaaatc aggccctgtt ctactggctc cttggtttta gcggcagcag
     6541 cagcgatcgg agcagagcct agtcctgatt cgttagaaaa aaccccacgt gcaataccct
     6601 tttgaatggc gtccttaacc aagcttccgg caaagccccc tatagctgct gtaggggtaa
     6661 tagcggactt aaagataagg acaagcatag gaagaagctt agtatagtga acagcaataa
     6721 ccgttaagct tgctccaata taaaagatag ccatgaaagg aacgactgtt tcagccacct
     6781 tggcaatagc ttgaatgcct ccaaaaataa tcatggccac aacagcagct agcaagacac
     6841 tgattaatgg cgaagagatc ccaaggctat ggtgtaggga tgaggtaatc gcattgacct
     6901 gagcaaatgt cccgattcca aacaaagcca ctaaaatacc agagacagca aataagttgg
     6961 ctagaggcct ccatttttgc cccataccat ttaaaatgta gtacataggt ccgcctgaaa
     7021 tctgaccatt agcgtcctta gtacggtatt taatggctaa aacgccctcg gaatatttgg
     7081 ttgccatacc aaagaaggca gcaacccaca tccaaaaaag tgccccaggt ccaccagact
     7141 ttatagcggt tgcgacacca acaatattac cagtaccaac tgtagcagct agggctgttg
     7201 ctagagcagc aaatgatgaa atatctcctt gcccctcatt cttagcaaaa atgagcctaa
     7261 aggccttagg caacttgatg acttggagaa ggctaagtct gctggtgagg taaatgccag
     7321 taccaagcag cagtagcaac aagggtgctc cccaaaccaa atcgtctatc cattttgcag
     7381 cagctatcat gcttaattcc tcaactctct taaccaatgc tgccaaaaga aaaagccacc
     7441 cctgcggata gcctctgaag catatgacaa aacagcaagc acaaaaaatg ctaaggaagc
     7501 atgatcatac ggcttgatat tttatcttct gtccttttgc ctgagagatt gagcagtctt
     7561 gccttgcccc ttcggcgcct aataggtctc tccagaagcc cgtccgtcaa gcagtcccgt
     7621 ccaacacctg aacacctgag agtataactc cttcggcgaa atccattctt ctcctgcatg
     7681 acatcattcg gtttattaaa ttatgtctat gatacccaaa aagcctagtg atgtcaacaa
     7741 gcaatttaac tgatggctaa ctccttgttt ttatggtaac atcattgtcc tcttttttct
     7801 ttttgactga aacatgatat aatcgtaagg ttaataaaag tcacttatta gacgatatga
     7861 ggagaaagca tgaatccttt attagatgga atgaatgata aacaagcaga ggcagttcaa
     7921 acgactgagg gccccttgtt aattatggct ggtgccggtt ctgggaaaac gagggtatta
     7981 acccaccgca ttgcctactt gattgatgaa aagtatgtta atccctggaa tattttggcg
     8041 attaccttta ctaataaggc tgcgcgtgag atgcgagaaa gggcattggc cttaagccca
     8101 gccaccaagg ataccttgat tgcgaccttt cactcaatgt gtgttcgtat tttacgccgt
     8161 gaggcagatc atattggcta caatcggaat ttcacgattg ttgatccagg agaacagcgg
     8221 accttaatga agagaatagt aaaagctcta aatctggatc ctaagaaatg gagcgagcgg
     8281 tcgattttag ccaccatttc aaatgctaaa aatgatctct tagatgaaag agcctatgag
     8341 ctaggagcct ctgatttgta tagccagaca gttgcccgct gctacaaggc ctatcaggag
     8401 gagctcagac gaagtgaggc tatggatttt gatgatttga ttatgatgac cttacgccta
     8461 tttgatcaaa atcctgacgt tctagcctat tatcagcagc gttatcaata tatacatgtc
     8521 gatgaatacc aagacacaaa ccacgctcaa tatcagctag tgactctttt agcctcacgc
     8581 tttaaaaata tttgtgttgt cggtgatgca gaccagtcca tttatggctg gcgtggtgct
     8641 gatatgcaaa atattttaga ttttgaaaag gattaccctg atgcaagggt ggttttgctg
     8701 gaagaaaatt atcgctccac caagaaaatc cttcaggcag ctaacgaggt gattcagcat
     8761 aatcgtcatc gtcgtccgaa aaaattgtgg actcaaaacg cagacggtga gcagattgtt
     8821 tattataggg caaatgatga gcgtgacgag gctgtttttg ttgcctcaac catcagcaat
     8881 atgtgtctag agctaggaaa gagctttaaa gactttgctg ttttatatcg taccaatgct
     8941 cagtcccgta cgattgaaga agccttgtta aaatcaaata ttccctacac gatggtcgga
     9001 ggaaccaaat tctacagcag aaaggaaatt cgtgatgtga ttgcctattt gactgtggtt
     9061 gctaatccgt cagataatct ctcctttgaa cgaattgtga atgagcctaa acgaggggta
     9121 gggccaggaa ccctagataa gctccgccaa tttgcttatg ggcaaggaca gtcattgtta
     9181 gaggccgctt caagccttga gcaatcaccg ctaaaaggaa aggctgccca agccatgctg
     9241 gccttagcga gtctcttaag tgatttgaga gctgatttag accagctgag cattacagcc
     9301 ctggccgagg ccttgctgga gaaaaccggc tatctggata tgctgcgcgt ccaaaatacc
     9361 ttagaaagtc aagctaggat tgaaaatatt gaagaattcc tgtctgttac caaaagcttt
     9421 gatgacctat cagcacagca gcaggagcat gaagcaggta ttgatcgctt aggaagattt
     9481 ctcaatgacc ttgctttgat tgctgatagt gatgatggca atgcagaaac cgctgaggta
     9541 actttgatga ctctgcatgc agctaagggg ctagaatttc ctgttgtttt tctcataggt
     9601 atggaggagg gagtctttcc tttagcccga gcagccgagg atcaagatga gctagaagaa
     9661 gaaaggcgac tagcctatgt tggcattacc agagccgagg aatgcttgtt tttaacgaat
     9721 gccaatacac gtaccctatt tggtaaaagc agctataatc gcccaacaag gtttttaaaa
     9781 gagatgtcag agaacctttt aagcttccaa ggcttggcaa gacctgctca tgcttccttt
     9841 ggtgtgacat tttcgcagca gggtcaacga caatttggca caggaatgag tctatcagag
     9901 gctatccagt ccagaaaatc aatggcacag cctgccagag cagcctcaac atctacaccg
     9961 ctgccctttg gaccgaatgc agctacttca aagcaagccg ttgattggca gattggtgat
    10021 attgcccatc ataaaaaatg gggtgctgga acggttttag aggtcaaggg atctggtaag
    10081 accatggaat taaccattag ttttcctgat gtcggattaa aaaaactcct tgccagcgtt
    10141 gctcctattg aaaaaaaata aaaggtacag cttatgggca atttgcatag tcacttggat
    10201 aagggctttg caattgcggt ttagttctgc gatttaagaa aagaagtaag caaggatttt
    10261 atcagttaac cacataccaa gcttttgatg gcct
//
LOCUS       DARYXW010000068        10267 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.068, whole genome shotgun sequence.
ACCESSION   DARYXW010000068 DARYXW010000000
VERSION     DARYXW010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10267
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.068"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            6..596
                     /locus_tag="TV191_001447"
     CDS             6..596
                     /locus_tag="TV191_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1507949.1"
                     /translation="MEGITKSYGAKLILKDFSYTFEQGKKYLIKGASGRGKSTLLHII
                     KGTAVDSGKIAFITKDNHSFESYQANIGMVSQAPFLFNGTLEENICLNQEFSKENILA
                     VLDQVHLLEELPAGLGFQIENNGTNISGGQRVRIELARFLLRQKDILLLDEVTAALDK
                     DNARRVRELIFSLPITIIEVAHHVDQAIAYDDMIEL"
     gene            606..2168
                     /locus_tag="TV191_001448"
     CDS             606..2168
                     /locus_tag="TV191_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1507950.1"
                     /translation="MFKYFNKYLVTLTLVACALNSLVFLIEPLITSKIFDLTFLNNHQ
                     DTLSFLGYGLTLYVVLYSVMFIANLLINHIMTIGCGRIRLRLYQNLILNYREMSHDKK
                     ISMLTQDVEYYLWNHISPSILLVSHVSNVLLLSAYLLSKNMLIGLIFIACAFVFLVVQ
                     HVIGQKAEQKGSELAVARQKLLGLLSDVVAGHSTLIQNQALFASLKQVKKQSEHYESS
                     RQAFEIFRSFFTLLAHLMLFISQFLPIFLGLALTLLGVKLRTTDLIAMFIAATRLEQP
                     LKNIVDDMFRLNGAKAIAKHFETLLEQPIPKYQSHAMTGDPFECLDGHHLAKSFAGRT
                     LFSDLSFHFEKGKKYLIKGSSGSGKSTLFKLILQEMSPDEGTLDMVLTGGQTTDNYHH
                     RIGLIAQSPYLFNDSIRYNLTLGEAFSDELLLEKLEQVGLTDEFDDILNHQIVNNGEN
                     ISGGQKTRLEIARSLIRQKDVLLADEVTAPLDVKNAKTIRQLLFSLPVTVIEIAHHID
                     DTFIYDGDIDLS"
     gene            2551..3652
                     /gene="prfB"
                     /locus_tag="TV191_001449"
     CDS             join(2551..2622,2624..3652)
                     /gene="prfB"
                     /locus_tag="TV191_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658142.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEL1507951.1"
                     /translation="MEVAEMRQQIVENKEKLTSFRRSLDLERLEEDIALLENKMTEPD
                     FWNDNMAAQKTSQELNELKLTYQTFHDMQELSDETELYLEMLDEDDSVKEELEASLIK
                     LSQMLASYEMTLLLSEPYDHSNAILEIHPGSGGTEAQDWADMLFRMYTRFGNAKGFKV
                     ETLDYQAGDEAGIKSVTLSIEGPNAYGFLKSEMGVHRLVRISPFDSAKRRHTSFVSVE
                     VMPELDDTIEVEIRDDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVASTVDRT
                     QYGNRDRAMKMLQAKLYQLEQEKKAEEVNALKGDKKEITWGSQIRSYVFTPYTMVKDH
                     RTNFEVAQVDKVMDGDIEGFIDAYLKWRMGED"
     gene            3703..4395
                     /gene="ftsE"
                     /locus_tag="TV191_001450"
     CDS             3703..4395
                     /gene="ftsE"
                     /locus_tag="TV191_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEL1507952.1"
                     /translation="MALIEMKGVSKKYRRSTTALRDINVSVNQGEFVYIVGPSGAGKS
                     TFIKLLYREEKLSSGSLKVGEFDLTKLRGREVPILRRSIGVVFQDYKLLPKKTVFENV
                     AYAMEVIGERRRHIKKRVPEVLDLVGLKHKMRSFPNQLSGGEQQRVAIARAIVNNPKL
                     LIADEPTGNLDPEISWEIMHLLERINLQGTTILMATHNSHIVNTLRHRVVAIENGRIV
                     RDEEKGDYGYDD"
     gene            4388..5317
                     /locus_tag="TV191_001451"
     CDS             4388..5317
                     /locus_tag="TV191_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1507953.1"
                     /translation="MIRHFFRHIWESIKNLRRNLLMTFASVSMVTVTLTLLGVFAATL
                     LNIQRVASGVENNIQINAYLQVDSTDAAKMVQSINGEQINNENYHKIYDQIAGLKGVE
                     RIIFSSKDEQLQKLQDSLGDVWGMYNEDSNPLQDIYIVETKTPKQVKSVTKAIKKIQG
                     IEDADYGGINSDKLFKFSKLIQTWGIIGTLLLLFIAIFLISNTIRMTIMSRQRDIAIM
                     RLVGAKNSYIRGPFFFEGAWVGLFGAILPSLIIYYGYEFAYKHFTPELQHNSLSMYPI
                     NPYVYYLIGMLFVIGIIIGSLGSVLSMRRYLKF"
     gene            complement(5707..6348)
                     /locus_tag="TV191_001452"
     CDS             complement(5707..6348)
                     /locus_tag="TV191_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEL1507954.1"
                     /translation="MTIMTLMNPVAGENTYLLVNDEAILVIDPGSKGQAILSQIHAIN
                     KPVAAILLTHTHYDHIMSLELVRESCQHPPVYVAKEEADWLYKPEMNLSGLIRHADLP
                     DIICKPAEKLFQYQTPYQLAGFHFSVVPTPGHSAGGVSFIFEQEEAVFTGDALFRESI
                     GRTDLPTGNLEQLLASIRDKLLTLPNHYQIYPGHGSATTISHEKNSNPFLRQR"
     gene            6685..9156
                     /locus_tag="TV191_001453"
     CDS             6685..9156
                     /locus_tag="TV191_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEL1507955.1"
                     /translation="MINEFSQKYAVIDLEATSPGPTASIIQVGIVIVEGKEIVDSYQT
                     DINPHEPLSDHIKALTGITDQQLAQAPDFSQVARTIFELIEDCVFVAHNVTFDANLLA
                     EALFLEGYDLLTPRVDTVELAQIFYPSLEKYSLSHLSEVLDLNLSDAHTAIADAQATA
                     NLFIKLLHKIESLPRECLETLLLYADSLLYETAMIVRQALAVSRPYSTSDYIKINQIL
                     LKKPDQLTKPYQLSQSFEINAALLGLEERPKQLSFAKIVEETLFQTEPAFIEAQAGIG
                     KTYGYLLPLLAQKHQTQILVSVPTKLLQDQIMANEVRAIQEQFHIDCHSIKGPANYIK
                     LDSFQESLNQLDDNRLVNRYKMQLLVWLLETRTGDLDEIKQKQRFAAYFDQIKHDGSI
                     QQTSPFYAYDFWQQSYQRAKSARLLITNHAYFLHRIQDDKAFAKGKILVFDEAQALML
                     QLEELAHQRLNIADTLQELQEQLAVPSSLLEQRLLEGIAFELNQLSSHYHQEEEKQQA
                     QASQHLLRLQEHVKELGAAASQSLKQLFKQQEMDYWVSSEQQADKRQTFLNGSSRTVL
                     QFKALLPEIFKAYFVSATLQISPSISLADLLGFDTYSYHQLAKEKSTQQLVVIDQDMP
                     LIKDLTDEAYTQTIAARLLVLHQQQQVPILVLFNAKKHMLMVSDYLEANQVQHLTQGK
                     NGTAYHIKKRFDRGEQSMLLGLAAFWEGVDFVHADRMIEVITRLPFDNPEDIATQKMQ
                     RYLQAAGKQPFNDYFLPMTILRLKQAIGRTLRRKEQKSAVLILDRRILTMSYGQTILH
                     SLEEEFLISQQNFQDSLAEIGDFLI"
     gene            complement(9330..>10267)
                     /locus_tag="TV191_001454"
     CDS             complement(9330..>10267)
                     /locus_tag="TV191_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEL1507956.1"
                     /translation="MYVDNRLKTGSWKPDTEANKEAIYKTHFKKYLGKTKMKDISRIE
                     YENHINGMRKNYSKNTLRLIHSVLNAMLNHAVTNKMLDDNPIDGITIGDSEIIPVNKR
                     ISLEEFKEWDSWAKKSLIQYDYTIVRMTYFGARSSEVVAIKIGNLTKLENGRYRILLD
                     ESRTYHRPNGGGMKTPGSERFMEVDLETSHYIDDVVVESKRIAKKYNRILSKEDYLFL
                     TNFKNAKKELLGMPISIRRVYKLFNTVNEKSGMHVTPHMMRHFFATQGQIAGVPIEHM
                     AAALGHSTSYMTSKYTHIKEEVAGSVTDRFMSALN"
BASE COUNT         2909 a         2018 c         2278 g         3062 t
ORIGIN      
        1 tggctttgga agggatcaca aagtcctatg gcgccaagct gatccttaag gatttttcct
       61 atacctttga acaggggaaa aaatatttga taaagggtgc cagtggtaga ggtaagtcga
      121 ctctgttaca cattattaag ggaactgctg ttgactcagg taaaatagcg tttatcacca
      181 aagacaatca ctcatttgaa agctatcaag ctaacattgg catggtgagt caggcacctt
      241 ttctctttaa tggcaccttg gaagagaata tctgtctgaa tcaggagttt tccaaggaga
      301 atatccttgc tgtcttggac caagttcacc tgttggagga attaccagct ggtctaggct
      361 ttcagataga aaataatggg accaacattt cgggcggcca gcgagtgcgc atagaattgg
      421 ctcgattttt gctacgtcag aaggatattt tattgcttga tgaggtcaca gcagccttgg
      481 acaaggacaa tgctcggcga gtaagggagc tgattttttc tcttcctatt accatcattg
      541 aggtggctca tcatgtggat caagctatag cttatgatga tatgatagaa ttgtaggtga
      601 ttaagatgtt taagtatttt aataaatatc tagtgacact aacgcttgtt gcatgtgcct
      661 taaacagtct tgtctttctg attgaaccct tgatcactag taagattttt gatttaacgt
      721 tcttaaataa tcatcaagac accttgtcct ttttaggcta tggtctgacc ttatacgtgg
      781 tcttatattc tgttatgttc attgctaatc ttctgatcaa ccatatcatg acgattgggt
      841 gtggtagaat caggttgcgt ctctatcaga atttaatctt aaattatcgg gagatgagtc
      901 atgacaagaa aatttctatg ctgactcaag atgtagaata ttatctatgg aatcacatca
      961 gccctagcat tcttctcgta tcacacgtga gtaatgtcct tttgctcagt gcttacctgt
     1021 tatcaaaaaa catgctaatt ggtcttattt ttattgcatg tgcttttgta tttttagtgg
     1081 ttcagcatgt gattggtcaa aaggcagagc aaaaaggtag tgagctggca gtagcgagac
     1141 aaaagctgct tggcttatta agtgatgtgg ttgcggggca ttcgacatta attcaaaatc
     1201 aagctctttt tgctagcctc aaacaggtaa aaaaacagtc agagcattat gagagctcac
     1261 gtcaagcatt tgagatattt aggtctttct ttaccctatt ggcacatctg atgctgttta
     1321 tttctcaatt cttgcccatt tttttaggct tagccttaac cttattaggt gttaagctga
     1381 gaacaactga tcttattgcc atgtttattg cagcaacgcg cttagaacag ccactcaaaa
     1441 atattgttga tgatatgttt aggcttaatg gtgcaaaagc cattgctaag cattttgaga
     1501 cacttttaga gcagcctatt ccaaaatacc agtcgcatgc tatgacaggt gatccttttg
     1561 aatgcttaga tggtcatcat ctggcgaaat catttgcagg taggacctta ttttccgatc
     1621 tctcttttca ttttgagaag ggaaagaaat acctgattaa gggatcaagt ggatctggta
     1681 aatccacact ctttaagctt atcttacagg agatgagtcc tgatgagggg acactagata
     1741 tggtattgac tggaggtcag acgactgata attatcacca tcgcataggg ctgattgcgc
     1801 agtcgcctta tctttttaac gatagcattc ggtataattt gaccttgggg gaggcgtttt
     1861 ctgatgagtt gcttttagaa aagctagaac aggttggctt gactgatgaa tttgacgata
     1921 ttttaaacca ccaaattgtt aataacggag aaaatatctc aggtggtcaa aagacacgtc
     1981 ttgaaatcgc aagaagcctc attagacaaa aagatgttct tctagcagat gaagtgacgg
     2041 ctccacttga tgtcaaaaat gctaaaacta tccgacagct actatttagt ttaccggtaa
     2101 cagttattga aattgctcat catattgatg acacctttat ctatgacggt gatattgatt
     2161 tatcgtagaa aatatcatca cattgcttag aaataataat tgatgcttat gaaattgtca
     2221 ttcacacagt gaatggcttt ttcttaggct aaattttcca tgtggagctt gatctgatag
     2281 gctatctgag aaaaaaagct aacaacagcc atgttttttg gggctatgac tgttctaata
     2341 cgagctgcct ctagctgctg gtatataaga ggtgacatga ttgtcacaat tcgtcatcat
     2401 tttgtcgtta aatttttaca tagatttctt atgctagtca tggcagagct ccttacccta
     2461 aaaagaaggg aatttagctg atgggaaata gcaattctaa agcctttatg ataaaatgaa
     2521 aaaagacact ataatagaag aggtaactgt atggaagtgg cagaaatgcg ccagcaaata
     2581 gtagaaaaca aagagaagtt gactagcttc aggaggtctc tttgacttag agcgtttgga
     2641 ggaggatata gctctcttag aaaataagat gacagagcct gatttttgga atgataatat
     2701 ggcagctcaa aaaacctctc aggaattaaa cgagctcaag ctcacctatc aaacctttca
     2761 tgatatgcag gagctatctg atgagacaga gctttattta gaaatgcttg acgaggacga
     2821 tagcgtcaag gaagagctag aagcaagcct gattaagctc agccagatgc tagcaagcta
     2881 tgaaatgacg ctgcttttgt ctgagcccta tgatcatagc aatgcaatcc tagaaattca
     2941 cccaggttca ggtggcactg aagcacaaga ctgggcagac atgctttttc gcatgtacac
     3001 tcgctttgga aatgccaagg gctttaaggt agaaactctg gactatcaag caggagacga
     3061 ggcaggaatt aagtctgtga ccctttctat tgaagggcca aatgcttatg gcttcttaaa
     3121 atcagaaatg ggagtacatc gtctggtgcg tatttctcct tttgactctg ctaagcgtcg
     3181 tcacacctcc tttgtttcag ttgaagtcat gccagagctt gatgatacca tcgaggtgga
     3241 gatacgtgat gatgacatta agatggacac cttccgctca ggtggtgctg gtgggcaaaa
     3301 tgtcaacaag gtctcaactg gggtacgctt gacccatatc ccaacaggaa tcgtagtggc
     3361 gtcaacagtt gaccgcaccc aatatggcaa ccgtgatcgc gctatgaaaa tgcttcaagc
     3421 caagctttat cagttagagc aggagaaaaa ggcagaagag gtcaatgccc tcaaggggga
     3481 taaaaaggag atcacctggg gcagtcagat caggtcctat gtctttacgc cttatacgat
     3541 ggtgaaggat catcgtacca attttgaggt ggctcaggtt gataaggtga tggacggaga
     3601 tattgagggt tttattgacg cttatctcaa atggcgcatg ggtgaggatt aaagtgatcc
     3661 ccactcagat aaacactaac agcttagaga aggaagaata agatggcatt aattgaaatg
     3721 aagggtgttt ctaagaaata ccgtcgctcg acaacagctc tgagagacat taatgtctca
     3781 gtcaatcaag gggaatttgt ctatattgtt ggtccatcag gagctggtaa atcaaccttt
     3841 atcaagcttc tttatcgcga agaaaagcta agctcaggca gcctaaaggt gggtgagttt
     3901 gacttaacca agctaagagg acgtgaggtt ccaattttac gtcgcagcat tggtgttgtt
     3961 tttcaggatt ataagttgct ccctaaaaaa acggtctttg aaaatgttgc ctatgctatg
     4021 gaggttatcg gagagagacg tcgccatatc aaaaagcgtg ttcctgaggt tctagacctt
     4081 gtcgggttaa agcataagat gcgctccttt cccaatcaat tgtcaggtgg tgagcagcag
     4141 cgtgttgcga ttgcacgcgc tattgtgaac aatcccaagc tcctcattgc agatgagcct
     4201 acaggcaatt tggatccgga aatttcttgg gaaatcatgc acctgcttga gcgtatcaat
     4261 ctacagggga caacgatatt aatggcaacg cataacagtc atatcgttaa tactcttcgc
     4321 catcgcgtgg ttgcgattga aaatgggcgt attgtccgcg atgaggagaa aggagactat
     4381 ggttacgatg attagacatt ttttccgtca tatctgggaa tctatcaaaa atttaaggcg
     4441 taatctcctc atgacctttg cgtcagtcag tatggtgacc gtcaccttaa ccctgcttgg
     4501 ggtctttgct gcaaccctgc tgaacattca acgtgtcgct tctggcgtgg aaaacaacat
     4561 tcaaatcaat gcttacttac aggttgattc gacagatgct gctaagatgg ttcagtcgat
     4621 taatggagag cagataaata acgagaatta ccataagatt tatgatcaga ttgcagggct
     4681 aaagggtgtt gagaggatta ttttctcaag caaggacgag cagctgcaaa agctacagga
     4741 tagtctgggc gatgtctggg gcatgtataa tgaggatagt aatcctctgc aagacatcta
     4801 tatcgtagag accaagaccc ctaagcaggt caaatcagtt accaaggcca tcaaaaagat
     4861 tcaagggatt gaagatgcgg actatggtgg tattaattct gataagcttt ttaagttttc
     4921 aaaactgatt caaacatggg ggattatcgg aacgctgttg ctcctgttta ttgcgatctt
     4981 tctgatttca aataccattc gcatgaccat catgtctcgt cagcgcgata ttgcgatcat
     5041 gcgtctggtt ggtgcgaaaa attcttatat tcgtggccca ttcttttttg aaggggcttg
     5101 ggttggtctg tttggtgcga tattgccatc gttgattatt tattatggct acgagtttgc
     5161 ctacaagcat ttcaccccgg aattacagca taatagcctg tctatgtacc ctatcaatcc
     5221 atatgtttat tatttaattg gcatgctttt tgtgattggt attatcattg ggtcactagg
     5281 atcagtctta tctatgagac gttaccttaa gttttaattg aaagagcttc tagcctgtgt
     5341 gcctggactg gtaccctgcg gttagggctc tttttgcttt tggggcaatg cttgctagat
     5401 aagcaaacaa tagcttaagc ccataccatt aagtattggg cttaagctat tgttatagtt
     5461 gtttaggtaa tagaagcagc cggaacttga ggtgtcctat ctaggtcttg agctatagct
     5521 tttctggcta gttggtgttt cttcacgtaa cagcgatttg tcgaacgata aggtgctctt
     5581 cttgtgatag ctggcttgta gtgatcgaca ggtgctaagt caaattagcc atcctgatgg
     5641 actggagtca tagcttttgc tgctgcgcct ggttgggcat agactgggca tctcggtagc
     5701 ttgagcttat cgctgcctca gaaagggatt gctatttttt tcatggctaa tggtggtagc
     5761 tgagccatgc cccggataaa tctgataatg gttaggaagt gttagcagct tatcacgaat
     5821 gctagcaagc agctgttcaa gatttccagt cggcaaatct gttctaccga tgctttctct
     5881 aaacagagca tcgccagtaa acaccgcctc ctcctgctca aagataaagg aaacgccacc
     5941 ggcagagtgt cctggtgttg gcactactga aaagtgaaat ccagctagct gataaggtgt
     6001 ctgatactga aagagctttt ctgctggttt gcagatgata tcaggcagat cagcgtgacg
     6061 tatcagtcct gacaggttca tttctggttt ataaagccag tccgcctcct ccttggcaac
     6121 atagacagga gggtgctggc agctctctct caccagctct aggctcataa tgtgatcata
     6181 atgcgtatgg gtcagtagga tagcagcaac aggcttgttg atggcatgga tttgtgataa
     6241 aatagcctgc cccttgcttc ctgggtcaat gactaaaata gcctcgtcat tgacaagaag
     6301 gtaagtgttt tcacccgcaa cgggattcat cagtgtcata atagtcatac ccttagttta
     6361 ccaaaatctg actcaaaaga cagctcaaaa ccacctcttt tgataaaagt gatctgttta
     6421 atggttttga tggctaagcc aagatagctc cagcttaaag gctgcttttt ttaattaata
     6481 ggagcaaaaa ggagctgcct cagcgctaac agctaatcag agtattagct ctctagtgtc
     6541 atagcaagga agtaggctgg ggcgattaaa aggcttgata actagctttt tatgatactg
     6601 actagcccta ttgagctgag ctaagactgg tattgtcaga tttaggcaaa gcctgtcaga
     6661 aaacgtgcta taatagatag tactatgatc aatgagtttt cacaaaaata tgctgtgatt
     6721 gacctggaag ccactagccc aggtccaaca gcgtctatta ttcaggttgg cattgtgatc
     6781 gttgaaggaa aagaaatcgt tgattcgtat caaactgata ttaatcctca tgagcccttg
     6841 tcagaccata tcaaagcact cacaggtatt acagaccagc agctagctca ggcaccggat
     6901 ttttcacagg tagcaaggac catttttgag ctgattgagg actgtgtttt tgttgctcat
     6961 aatgtcacct ttgacgccaa tttgttggca gaagccttat ttttggaggg ctatgatctc
     7021 ctcactccta gagtggatac tgttgagctg gctcagattt tttaccccag cctagaaaaa
     7081 tacagcctta gccacctatc agaggtgcta gacctaaacc tatctgatgc tcataccgct
     7141 attgctgatg ctcaggcgac tgctaactta tttatcaagc tgcttcacaa gatagagagc
     7201 ttgccaagag aatgcttgga gactcttttg ctgtatgctg atagtctgtt atatgagaca
     7261 gctatgattg tgagacaagc ccttgcagtc agtcggcctt attctacgag tgactacatc
     7321 aagattaatc agatcttgct aaaaaagccg gatcagctaa caaagcccta tcaattatcc
     7381 cagtcctttg agattaatgc agccctctta ggtcttgagg agcgccccaa gcagctcagc
     7441 tttgcaaaga ttgttgagga gactcttttt cagaccgagc cagcctttat cgaggctcag
     7501 gcaggcattg gtaaaaccta tggctattta ctgcctctcc ttgcacagaa acatcagacc
     7561 caaatcttgg ttagtgtgcc aaccaagctg ctacaggacc aaatcatggc taatgaggtg
     7621 agggctattc aggagcagtt tcacatcgat tgccatagta tcaaggggcc tgctaattac
     7681 atcaagctag acagctttca agagagcctc aatcagcttg atgacaaccg cttggttaat
     7741 cgctataaaa tgcaattgct ggtttggctt ttggaaacaa ggactggtga tttagatgaa
     7801 atcaagcaaa agcaacggtt tgcagcttac tttgaccaga tcaagcatga tggcagtatc
     7861 cagcagacct cgccctttta cgcttatgat ttttggcaac aaagctatca aagggctaag
     7921 tcagctcgct tgctgatcac caatcatgcc tattttttac accggattca ggacgataag
     7981 gcatttgcca agggtaagat tctagtcttt gatgaagctc aggccttaat gctgcagcta
     8041 gaggagctag ctcatcagcg actaaatata gctgatacgc tccaagagct tcaagagcag
     8101 ctagctgtgc caagcagctt gcttgagcaa cgcttgctag agggcattgc ctttgagctc
     8161 aatcagttaa gcagtcatta tcatcaggag gaggagaagc agcaagctca agcctcacag
     8221 catttgctgc ggctccaaga gcatgtcaag gagctaggtg ctgcagcctc tcagagcctc
     8281 aagcagctgt tcaagcagca ggaaatggat tattgggtga gcagtgagca gcaggctgac
     8341 aagcgccaaa cctttttaaa tggcagcagc aggacggtcc ttcagtttaa agcattgcta
     8401 ccggagattt ttaaggccta ctttgtctca gctactctac agattagccc tagcattagc
     8461 ttggctgatt tattgggctt tgacacttat tcttatcatc agctggctaa ggagaaaagc
     8521 actcagcaat tggttgtcat tgaccaagac atgcccttga ttaaggactt gactgacgag
     8581 gcttacacac agaccatagc agcaaggcta ttagtgcttc atcagcaaca gcaggtacct
     8641 atcttagtgc tctttaatgc taaaaagcac atgctcatgg tttctgacta tttagaggct
     8701 aatcaggtgc agcacttgac acaaggcaaa aacggtacag cctatcacat caaaaagcgc
     8761 tttgatcgtg gtgagcaatc aatgctgctg gggcttgcag ccttttggga gggagttgac
     8821 tttgttcatg ctgatcgcat gatagaggtc attacccgcc tgccctttga taatccagaa
     8881 gatattgcca ctcaaaaaat gcagcgctac ctacaggcag caggtaagca gccctttaat
     8941 gattattttc tgccgatgac gatcttaaga ttaaagcagg cgattggtcg aaccctgcgt
     9001 cgaaaagagc agaaatcagc agttttgatc ttagatcgtc gcattctgac catgtcctat
     9061 ggtcagacca ttttgcacag cctagaagag gaatttctga tatcacaaca aaatttccaa
     9121 gatagtctag cagaaatagg cgattttttg atataatgaa aaatagtaat ttttatttag
     9181 ttattttaat ttatttattt tgcaaatgtt tatttatagg catttgcttt tttgtttaat
     9241 tgataccaaa taataaaaat ctataaattg tcggggaata tatcggggga tttgttaatt
     9301 taagcatttg tataaatttc cccgactaac tagtttaaag cgctcataaa tctatcagta
     9361 acactaccag caacctcctc ctttatgtga gtatatttgc tagtcatgta acttgtagaa
     9421 tgacctagtg ctgcggccat atgttcaatt gggacacctg ctatctgccc ttgggtggcg
     9481 aaaaagtggc gcatcatgtg tggggtaaca tgcataccag atttttcatt gacagtatta
     9541 aaaagtttat agactcgcct aatagagatc ggcattccta aaagttcttt tttcgcattc
     9601 ttaaagttag tcaaaaatag gtaatcctct tttgataata tacgattata cttctttgca
     9661 atccttttag actcaacaac aacatcatca atataatgcg atgtttcaag atcaacttcc
     9721 ataaaccgct ctgatcctgg cgttttcatt cctccaccgt ttggacgatg gtacgtccta
     9781 gactcatcta gcaatattcg atatctacca ttttcaagct ttgttaaatt gccaattttt
     9841 atggcaacaa cttcgctact acgagctccg aagtaagtca tacggacaat agtataatca
     9901 tattgaatca atgacttctt ggcccatgaa tcccactctt tgaattcttc aagcgatatt
     9961 cttttgttaa cgggtataat ctcactatcg ccaatagtta tcccatcaat tggattgtca
    10021 tctagcattt tattggtgac tgcatgatta agcattgcgt tgagtactga atggatcaag
    10081 cgtaaagtgt tctttgaata attcttacgc ataccattaa tatgattttc atactcaatt
    10141 ctagaaatat ctttcatttt agtcttgcct aaatattttt tgaagtgagt tttgtatata
    10201 gcttctttat ttgcttcggt atcaggtttc catgatccgg tctttaggcg attatctaca
    10261 tacatat
//
LOCUS       DARYXW010000069        10250 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.069, whole genome shotgun sequence.
ACCESSION   DARYXW010000069 DARYXW010000000
VERSION     DARYXW010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10250)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10250)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10250
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.069"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            23..307
                     /locus_tag="TV191_001455"
     CDS             23..307
                     /locus_tag="TV191_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1507957.1"
                     /translation="MSEEATLVVQLPKVLEKQLRAHYDEMVSTAIERALEDKELYKPM
                     VRMAALSRWLDVSTTTLQKWTREGMPTMVIDGVTLYDKRAVTRWLKQYER"
     gene            316..801
                     /locus_tag="TV191_001456"
                     /pseudo
     CDS             316..801
                     /locus_tag="TV191_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643974.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein DnaD"
     gene            853..1140
                     /locus_tag="TV191_001457"
     CDS             853..1140
                     /locus_tag="TV191_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEL1507958.1"
                     /translation="METLWHRELTQQEKVLLEGFAVNDSLLQLAIQKTEELEPKKQNM
                     SYVKGILMNWEARGFITVDQVIASEEDYRPLEIANVEVSEDFLAAMDIWKD"
     gene            1155..1445
                     /locus_tag="TV191_001458"
     CDS             1155..1445
                     /locus_tag="TV191_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507959.1"
                     /translation="MTVYYQLENMLVAGFKSQDEYDRYQALKRDYEGESEDYSFSIRE
                     ITNQLEIICQTSENDFPNLSEALMIDYLELVGELKRYDTNQADRYLGMVRHV"
     gene            1438..1800
                     /locus_tag="TV191_001459"
     CDS             1438..1800
                     /locus_tag="TV191_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL1507960.1"
                     /translation="MSERIRTILKKFYVTELQNEVLNQLVNDTGLQTFSNYARRMLFK
                     ETSLFMRFDESQFDELIYSLRRIQNNLRQLSKIAEQSQDSQAYRAMDYSRRLVSHYEK
                     QLTRYHKKKKRKLLSKGA"
     gene            1800..2156
                     /locus_tag="TV191_001460"
     CDS             1800..2156
                     /locus_tag="TV191_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL1507961.1"
                     /translation="MDKRRIRNVIKQVFLSEEENQKLLEKMKQDGFTNFSLFARKQLL
                     KPDFETWLVSFPEYQPLTGRLLSVGRTINGIAKSATQFGKISQHDLMELGQLMEELVE
                     LVEKQVKEDKQRIAKK"
     gene            2500..4044
                     /locus_tag="TV191_001461"
     CDS             2500..4044
                     /locus_tag="TV191_001461"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HEL1507962.1"
                     /translation="MSEQAQRQELHRKIWAIADDVRGAVDGWDFKQYILGILFYRFIS
                     ENFKTYIEGGEDFNYEEIPDEVITPEVKDDAIKTKGYFIMPAQLFSNVVKTARSNDNL
                     NTELKDIFDAIEASAMGYASENDIKGLFDDVDTRSNKLGSTVPERNERLALILEGIAS
                     LDFGSFEDNHIDLFGDAYEFLISNYASNAGKSGGEFFTPQSVSRLLARIVMLGKDEKN
                     KINKIYDPACGSGSLLLQAKKQFTEHIIEDGFYGQEINMTTYNLARMNMFLHNINYDK
                     FSIERGNTLLDPKHGNDKPFDAIVSNPPYSIKWVGSDDPTLINDDRFAPAGILAPKSK
                     ADFAFIMHSLSYLSNKGRAAIVTFPGIFYRGGAEQKIRQYLVDGNFVETVIQLPDNLL
                     FGTSIATCILILAKNKPTTDVLFIDASQQFKKETNNNVLTEENIEKILKSVEHKNNEE
                     YFAQLISQEKIVEADYNLSVSTYVEKEDTREKINIDVLNKEIAETVKNIDRLRAEIDK
                     IVEELS"
     gene            4046..5308
                     /locus_tag="TV191_001462"
     CDS             4046..5308
                     /locus_tag="TV191_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002892408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEL1507963.1"
                     /translation="MTYIDEMIKELCPDGVEWKELGEVVDYEQPTKYIVKSKEYSDDY
                     SIPVLTAGQTFILGYTNEVTGIYPASKEHPVIIFDDFTTARKWVDFEFKVKSSAMKLL
                     SIKSDRQDDVSIRYVWHYLGTIKYTPEQHARQWIGTFSKFKIPLPPLEIQGEIVKILD
                     KFTEHVTELTAELTAELTFRQKQYSYFRDKLLSFDDESMGGANDKVYTVQWKTLGEVV
                     NFRRGSFPQPYTDMSFYGGEDAQPFVQVVDVADEGFRLNTKTKKTISQKAIPKSVFVP
                     KGTVIVTLQGTLGRVAVTQYDAYVDRTLAIFDGYKQEVDKRYFAHQLKFIFDREKEFA
                     RGSTLKTITKQEFSNFKIPVPPLDIQRRIVQVLDNFDTVCNDLNIGLPKEIELHQKQY
                     AYFRDKLLTFTAEGVYTDSTVQYSTDKT"
     gene            5317..5922
                     /locus_tag="TV191_001463"
     CDS             5317..5922
                     /locus_tag="TV191_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEL1507964.1"
                     /translation="MTWVFGPIKVELGAVCDVVRGNGLQKKDFVNEGYPVIHYGQIYT
                     FYGLSARVTKSFVSPEVGQKLKKAKTGDVIVATTSENIEDVGKALVWEGAEDVCIGGH
                     SCVLHTEQNSKYLLYYFQTTVFQKQKEKLVIGTKVIELYPKNLEKAIIILPPVYEQGR
                     IVSILDKFDTLTSDLTQGLPKEIEQRQKQYEYWRDLLLNFP"
     gene            5937..7145
                     /locus_tag="TV191_001464"
     CDS             5937..7145
                     /locus_tag="TV191_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEL1507965.1"
                     /translation="MGNDIKFENLEQISDNIISSNKKVHLLYAYNATGKTRLSMELKN
                     KVNETDSDGNSIKHILYFNSYTEDLFTWDNDLENDEDRYLIYDKRTYFGNFLEEQQLF
                     ERAVDNFQKYVGRSIDIEFQDVIETVKDEFGNVQKDNRGEALTISNKKSIRFKVDGHT
                     IKVSRGEERIFVWSVFLTLLEIIIEDLTESADTSEFSKMNYIYIDDPISSLDDTNIIN
                     AAIYLSDVIGSAENTDLKFVVSTHQALFYNVLYNEIRFDRRIKKKVFYVMKATDEIED
                     EKQFKYLLTDVEGDSPFGYHLRVREELRKAIQDEQVEKFHFALFRNLVEKTATFLGYG
                     RWENILLGLDVAGHVITSENIKLYTQLIDLYTHNRHADLEYRELPPQEKNTLINLFNS
                     FDSIYRFKED"
     gene            7148..10243
                     /locus_tag="TV191_001465"
     CDS             7148..10243
                     /locus_tag="TV191_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019771596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HEL1507966.1"
                     /translation="MTEIIQTDTILEAKNFIVLEKYTKLEKPSTYQTEADLERELVSD
                     LRQQGYEYLNNLTTPEALLDNLKTQMEALNGVVFSEAEWLRFLEEYLNKPSDGLIDRT
                     RKLHDNHIYDFIFDDGHIQNIYLWDKKNISRNKLQVINQMSQVGTSSNRYDVTILVNG
                     LPLVQIELKKRGVAIREAFNQVHRYSKESFNEENSLFKYLQIFVISNGTDTRYFANTT
                     KREKNSFDFTMNWALKNNEPIKDLKDFTATFFSQQTLLNILINYSVFDTSDTLLIMRP
                     YQIAATERIIWKIRSAIDSKIKSGPETGGYIWHTTGSGKTLTSFKAARLATEMDKVDK
                     VFFVVDRKDLDYQTMKEYQRFSPDSVNGSNSTAGLKRNIEKDDNKIVVTTIQKLNNFM
                     SSEAQHEIYNKQVVFIFDECHCSQFGEAQKRLKQKFKKYCQFGFTGTPIKVENALGSE
                     TTASVFGRELHAYVITDAIRDQKVLKFKVDYNDVRPQFKSLETEQDLGKLSAAENKKA
                     LLHPTRITEISAYILEHFNQKTHRQNGKGFNAMFAVSSVEAAKAYYQELQDQQAGKAK
                     PLKIATIFSYAANEEQAAIGEIDDETFSPADLSDISSKEFLSGAISDYNRLFQTNFSI
                     NGNEFQNYYRDLAKRVKSGEVDLLIVVGMFLTGFDAPTLNTLFVDKNLRYHGLIQAFS
                     RTNRIYNATKTFGNIVTFRDLEKATTDAIKLFGKTETADILLERSYEDYMNGYIEAGQ
                     EQKGYLEVVKELQERFPDPTTIIKESDKKEFVTLFGQFLRLDNILQNYDDFMSLQALQ
                     ELDVTDIEALADFKGRFHLDDEAVAVLSQLDIPSVREIQDYRSAYNDIKSWYDNERRN
                     QQNNDSEIDWDAVVFEVELLKSQEINLDYILELIFETNQKVSDKDQLIEEITRTIRAS
                     LGQRAKESLIVDFINASDLDSFSEKSDILEQFYTFARQKQKEAVANLIETEGLNVESA
                     SRYIQMSLKREYASENGNALNEALPKMSPLNPQYRTKKQMVFEKIVDLVEIFKGIGGE
                     I"
BASE COUNT         3331 a         1655 c         2279 g         2985 t
ORIGIN      
        1 gaaatggaaa cgaggtaatg atatgtctga agaagcgact ttagttgttc aacttcccaa
       61 agttttggaa aaacaattaa gggcacatta tgatgaaatg gtttctacag ctattgaaag
      121 agcgctagag gataaagaat tatataaacc tatggttcgg atggcagccc tttctagatg
      181 gcttgatgtg tcaacgacaa cacttcaaaa gtggacgcga gaaggaatgc ctacaatggt
      241 tattgatggt gtgactctgt acgataaacg tgcggttaca cgttggttga agcaatatga
      301 aagatgaggt aaagaatggc taatagacga atgttgagta aaacggtggt gcagatacaa
      361 cgatttttac gcctaccact tgaagcgcag gcgctttact gtcacttggt agtcaatgca
      421 gatgatgatg gtattgttga agcttttcct gttatgcgga tgattaatgc taatgaggac
      481 agtttgaatt tattaactct taagcagtat ttactcttgt taaacaatga aatggtttac
      541 tttatcaagg atttctttga gcagaatacc atcaaagcag atcgttacac accgagtagt
      601 catcgtcaac ttcttataga ttatctgaag gataatcagt tgttggagtg tctaaatcta
      661 ggaccacgct tgattaatta tcttcaaaat actcggctcc aagttggagc cagtctggat
      721 ccagatggga accgcaatat aattaaagat aagataagta aagataggat aggtaaagat
      781 aagttaagtc aagataagat aggattagat aatgatccaa tctcatcaca actgactgat
      841 gacatctggt taatggaaac actatggcat cgagaattaa cccaacagga gaaagtatta
      901 ttagaaggat tcgcggttaa tgattcttta ttgcagttag ctattcagaa aacagaggag
      961 cttgagccaa agaaacaaaa catgagttat gtcaaaggga tactaatgaa ttgggaagct
     1021 agagggttta taactgttga ccaagtgata gcatctgaag aagactaccg tccattagaa
     1081 attgcaaatg tagaagtttc agaagatttc ttagcagcta tggatatatg gaaagactag
     1141 gggaataatg agttatgaca gtatattatc aattagaaaa tatgttagtg gctgggttta
     1201 agtcacaaga tgagtacgac cgctatcagg ctctcaagag ggactatgaa ggggagtcag
     1261 aggactatag cttttcaatc agagaaatca caaatcaact tgaaatcatt tgtcagacct
     1321 cagagaatga ttttccgaac ttatcagaag cattaatgat tgattattta gaactggtag
     1381 gagagttgaa acgatatgat actaatcagg cagacaggta tttagggatg gttcgtcatg
     1441 tctgaacgta tcagaactat tttaaagaag ttttatgtga cggaattgca gaatgaagta
     1501 cttaatcaac tagtaaatga tacaggcttg caaacattct ctaattatgc tcgtcggatg
     1561 ctttttaagg aaacatcact ctttatgcga tttgatgaat ctcagtttga tgagttgatt
     1621 tattctttaa ggcgtattca aaataattta aggcagttat ctaaaattgc agagcagtct
     1681 caagatagtc aagcctacag agctatggac tatagcagaa ggttagtttc acattatgaa
     1741 aagcagttaa cgcgttacca caagaaaaag aaacggaaat tattatctaa gggagcttaa
     1801 tggataaaag gagaattagg aacgtaatta aacaagtctt tttgtctgaa gaagaaaatc
     1861 aaaaactgtt agagaaaatg aagcaagatg gcttcacaaa cttttctctt tttgctagaa
     1921 agcaattatt aaaacctgat tttgaaactt ggctagttag ttttccagaa tatcagccgc
     1981 tgactggcag gttactatct gttggtagaa caattaatgg catcgctaaa agcgcaacac
     2041 agtttggaaa aatttcccaa catgatttga tggaattagg tcagttgatg gaggaacttg
     2101 tagaactggt agagaaacaa gtgaaggaag acaagcaacg aatagccaag aagtgatagt
     2161 cgttcagtca ttttggtaga atagttttaa ataaaacaac aaaaacgctg atggtagtca
     2221 gcgtttttta gcatgtaatt gtaaaaaatc cttgtacgga caatgtgcgg caccgtataa
     2281 agtacgggaa atcactaaaa atggagttag gtctttgcga gctcagatag tgtatacaca
     2341 ctatcgtaaa aatagaacca tcagtaaagg tcagactgac actttttgat tgatgcttat
     2401 attttatttt ggggcaaagc cccaaacccc ttgagaaaac gtgtgagaag tagggaaaaa
     2461 tggtataata gaaatattaa agactgtgag gatttgaaga tgtcagaaca agcacaaagg
     2521 caagagttgc accgcaaaat ctgggcaatc gcagatgatg tccgtggtgc ggtagatggt
     2581 tgggatttca aacaatatat tttgggaatc cttttttacc gttttatcag tgaaaatttc
     2641 aagacttata tcgagggtgg tgaggacttc aactatgagg agattccgga tgaagtaatc
     2701 acacctgagg ttaaggatga tgcgattaag acaaaggggt actttattat gcctgcgcag
     2761 cttttttcca atgttgtgaa aacagctcgt agtaatgaca acttaaatac ggaactcaag
     2821 gatatttttg atgccattga ggcgagtgct atgggttatg ccagtgaaaa tgatattaaa
     2881 ggtctttttg atgacgtaga caccagaagt aataagctag gaagtaccgt cccagagcgt
     2941 aatgaacgct tagcccttat cctagaaggt attgccagcc ttgattttgg tagtttcgag
     3001 gacaatcata tcgacctttt tggcgatgcc tatgagtttc tgatttctaa ctacgcttct
     3061 aacgccggga aatcaggcgg agagtttttc acaccgcaga gcgtgtcacg gctcctagca
     3121 cgtatcgtca tgttaggcaa ggatgaaaag aacaaaatca ataagattta tgaccctgct
     3181 tgtggttctg gttctctctt gcttcaagcc aaaaaacaat ttacggagca tattatcgag
     3241 gatggttttt atggtcagga aatcaacatg accacctaca acttggctcg gatgaatatg
     3301 ttccttcata atatcaacta cgacaagttt agcattgagc gtggcaatac gctgctggac
     3361 cctaagcatg gcaatgataa gccctttgat gctatcgtgt ccaacccgcc ttattcaatc
     3421 aagtgggttg gtagcgatga cccgacgcta attaatgatg accgttttgc accagcgggg
     3481 attctggcac ccaagtctaa agcggatttt gcttttatca tgcatagcct ttcttatttg
     3541 tccaataaag gcagagcggc tattgtgacc ttccctggga ttttttatcg tggtggagcg
     3601 gagcaaaaga ttcgtcagta tttggtagac ggaaactttg tcgaaactgt tatccaattg
     3661 ccggataatc tcctttttgg gacgtctatc gctacctgta tccttattct tgctaagaat
     3721 aagccgacaa cagatgttct cttcattgac gctagccagc agttcaaaaa agaaaccaat
     3781 aacaatgtct tgacagaaga gaacatcgag aaaattctga aaagtgttga gcataagaat
     3841 aatgaagagt attttgctca gctcatttcc caagaaaaaa ttgtggaagc tgactacaat
     3901 ctctctgtat ctacctacgt ggaaaaagag gatacgcgtg agaagattaa tattgatgta
     3961 ttaaacaaag aaattgctga gaccgtgaaa aatattgacc gattgcgggc agagattgat
     4021 aagattgtcg aggagttgag ctgatatgac ctacattgat gagatgatta aagagctttg
     4081 tcctgacgga gtggagtgga aagagttggg tgaagtcgtt gactacgaac agccaacaaa
     4141 gtatatcgta aaatctaagg aatacagcga tgattattcc attccagttt tgacagcagg
     4201 tcagacattt attcttggat acacaaatga agtaactggt atttatccag caagtaagga
     4261 acatccagtt attattttcg atgactttac gacagctaga aagtgggtgg attttgaatt
     4321 taaagttaag tcctcggcga tgaaactact ctctatcaag tcagaccgtc aagatgatgt
     4381 ttcaataagg tatgtttggc actatttagg aacaataaaa tacacaccag aacagcacgc
     4441 acgacagtgg atagggactt tttctaaatt taaaatcccc cttcccccac tagaaattca
     4501 aggggagata gttaaaatac ttgacaaatt cacggaacat gttacagaat tgaccgcaga
     4561 attgaccgca gaattgacct ttcgacagaa acaatattct tattttagag ataagctcct
     4621 aagttttgat gatgaaagta tgggaggggc gaacgataag gtttacactg tccagtggaa
     4681 aacgctgggg gaggtggtga attttaggag agggtctttc cctcagcctt acacagatat
     4741 gtcgttctat ggtggagaag atgcccaacc atttgttcaa gttgtagatg ttgctgatga
     4801 aggatttaga ctgaatacta aaacgaaaaa aacaatttct caaaaagcta ttccaaaaag
     4861 tgtttttgta cctaagggaa ccgttatcgt taccttgcaa ggcaccctag gaagggtagc
     4921 ggttacccag tatgatgctt atgtcgatag aacgttagca atttttgacg gttataagca
     4981 agaagttgat aaacgctatt tcgcacacca attgaagttt atttttgaca gagaaaaaga
     5041 atttgctaga ggaagtactc tgaaaacaat aacaaaacaa gaattctcga atttcaaaat
     5101 cccagtccct cctctggata ttcagcgtcg tattgtccaa gttttggata attttgatac
     5161 ggtttgtaat gacctaaata tcgggctacc taaggagatt gagcttcatc agaaacagta
     5221 tgcctatttt agagacaaac tcttgacctt caccgccgaa ggcgtgtata ctgacagtac
     5281 agtacagtac agtacagaca agacctaatt aggctcttga cttgggtttt tggaccgatt
     5341 aaggttgagt tgggggctgt ctgcgatgtg gtgcgtggga atggtttgca aaagaaggat
     5401 tttgttaatg agggttatcc tgttattcat tatggacaaa tctatacctt ctatggattg
     5461 agtgctcgcg tgacgaaatc ttttgtgtca ccagaagttg gtcaaaaatt gaaaaaagct
     5521 aaaactggtg atgtgattgt agctactact tctgaaaata ttgaagatgt tggtaaagca
     5581 cttgtttggg aaggtgctga agatgtttgt attggtggac actcttgtgt attgcacacg
     5641 gaacaaaact cgaagtactt gctttattat tttcagacaa ctgtgtttca aaagcaaaag
     5701 gaaaagttag tgataggaac taaagtgatt gaactgtatc ctaaaaattt agaaaaggcg
     5761 attattattc tcccacctgt atacgaacaa gggcgtatcg tctccattct tgacaaattt
     5821 gatacactaa cttctgacct tacccaaggt cttccgaaag aaattgagca acgacagaaa
     5881 cagtatgagt attggcggga tttactactt aactttccgt aggaggaaga atagatatgg
     5941 gaaatgatat caaatttgaa aatttagaac agatttcgga taatattatt tctagtaata
     6001 agaaagttca tttgctatat gcctataatg ctactgggaa aactaggctt tctatggaat
     6061 tgaaaaataa ggtaaatgag actgatagtg atggtaatag cattaagcac attttatatt
     6121 tcaattcata tacggaggat ctttttacgt gggataatga tttggaaaac gatgaagatc
     6181 gatatttgat ttatgataaa cgaacttatt ttggaaattt ccttgaagag caacaacttt
     6241 tcgaacgtgc tgtagacaat tttcaaaagt atgttggtag atctattgat attgagttcc
     6301 aagatgttat tgaaacagtt aaagatgagt tcggaaatgt tcaaaaagat aataggggtg
     6361 aggcactaac aattagtaat aaaaagagta taagatttaa agtagatggg catacaataa
     6421 aggtgtctag aggagaagag aggatttttg tttggtcagt tttcttaacg ctccttgaaa
     6481 ttattattga agatttgact gagtctgctg atacctcaga attttcaaaa atgaactata
     6541 tctatattga cgatcctata tcttctttgg atgatactaa tattattaat gctgcaattt
     6601 atttgagtga tgttataggt agtgctgaaa atactgattt gaaatttgtc gtctctactc
     6661 atcaagcatt attttataat gtactttata atgaaatccg atttgataga agaatcaaga
     6721 aaaaggtttt ttacgtcatg aaagctactg atgaaattga ggatgagaaa caatttaaat
     6781 atttgttgac agatgttgaa ggggattctc catttggata tcatctcaga gtgagagaag
     6841 aattgagaaa agcaattcaa gatgaacagg tagagaaatt ccattttgct ctttttagaa
     6901 acctagttga aaaaacagca acatttttag gatatggacg atgggaaaat atcttgttag
     6961 gtttagatgt tgctggacat gttataacat ctgaaaatat taaactctat acacaactga
     7021 ttgatttata cactcataat aggcatgctg atttagaata tagagaattg cctccccaag
     7081 agaaaaatac tcttataaat ttatttaata gctttgattc aatctatcga tttaaagagg
     7141 actaactatg actgaaatca tccaaacaga tactatttta gaggctaaga acttcattgt
     7201 actggaaaaa tacaccaagt tggaaaagcc tagcacctat cagacggaag cagacttgga
     7261 gcgagagctg gttagcgatt tgcggcagca gggatacgag tacctcaaca atctgacgac
     7321 cccagaagct ctcttagata acctaaagac ccagatggaa gcccttaatg gcgtggtttt
     7381 ttctgaggca gaatggctgc gttttttaga ggagtacctc aataagccta gtgatggttt
     7441 gattgaccgc acccgaaagc tccacgataa ccacatctac gactttatct ttgacgatgg
     7501 gcatatccaa aatatttatc tctgggataa gaaaaatatc agtcgaaata agcttcaggt
     7561 cattaaccaa atgtctcaag ttgggacttc aagtaaccgt tatgatgtga ccattttggt
     7621 taatgggcta cccttagtac aaattgagct taaaaagcgt ggggtggcta ttcgtgaggc
     7681 tttcaaccag gttcaccgtt acagtaagga aagctttaat gaggaaaatt cgctcttcaa
     7741 gtatctccag atttttgtca tttcaaatgg gacggatact cgctattttg ctaataccac
     7801 taagcgagag aaaaattctt ttgactttac catgaattgg gcactaaaaa ataatgagcc
     7861 aatcaaggat ttgaaggatt ttacagcgac cttcttcagt cagcagacac tcttaaacat
     7921 tctcatcaac tactcagttt ttgatactag tgataccctc ctaatcatgc gtccctatca
     7981 gattgctgcg acggagcgca tcatctggaa gattcgttcg gccattgata gcaaaatcaa
     8041 gagtggtcct gagactggcg gctatatctg gcatacgacg gggtctggta agaccttgac
     8101 cagttttaag gctgcgagac tggcgactga gatggataaa gtggacaagg ttttctttgt
     8161 ggttgatagg aaagacttgg actaccagac tatgaaagaa taccagcgtt tttcacctga
     8221 ctcagttaat gggtcaaata gcacagctgg acttaaacgc aatatcgaaa aagatgacaa
     8281 taagattgtt gtgacgacga ttcaaaagct caataacttt atgtctagtg aagcacagca
     8341 tgagatttac aacaagcaag tggtctttat ctttgacgaa tgccactgtt cacagtttgg
     8401 cgaggctcaa aagcgcttaa aacaaaagtt taagaagtat tgtcagtttg gttttacagg
     8461 cacgccgatt aaagttgaaa atgctttagg cagtgagacg acagcttctg tattcggtcg
     8521 ggagcttcat gcatacgtca ttactgatgc tatccgtgac caaaaggtgt tgaaatttaa
     8581 ggtggattat aatgatgttc gtccacagtt taagtcgtta gaaactgagc aagatttagg
     8641 gaaattatct gctgctgaaa ataaaaaagc cctacttcat ccaacacgga ttacagagat
     8701 ttcggcttat attttagaac attttaatca aaagacacat aggcaaaacg gtaaaggatt
     8761 taacgctatg tttgctgtgt caagtgtcga ggcggccaag gcttactacc aagagttgca
     8821 agaccaacaa gctggaaaag ctaaaccatt gaagattgca accatcttct cttatgcagc
     8881 aaatgaggag caggctgcga ttggggagat tgatgacgag actttcagcc ctgctgactt
     8941 gtcagatatt agtagtaagg aatttttgag cggagcgatt tccgattata atcgcctttt
     9001 tcagactaat tttagtatca atggcaatga gtttcaaaac tattaccgtg atttagctaa
     9061 gcgagttaag tctggagaag tggatttgct gattgtcgtt ggtatgtttt tgactggttt
     9121 tgatgcacca accttgaata ctctttttgt ggataaaaac ttgcgttatc atgggcttat
     9181 tcaggctttt tctcggacga atcggattta taatgcgaca aagacatttg gaaatattgt
     9241 aactttccgt gatttggaga aggctacgac ggatgctatt aagttgttcg ggaagacgga
     9301 gacggctgat attctgttag agcgctctta cgaggactac atgaatggct acattgaggc
     9361 tggtcaagag caaaaaggat atttggaagt cgtaaaagaa ttgcaggaga gatttccaga
     9421 tccaacgact attatcaaag aaagtgataa gaaagaattt gtgaccttgt ttggtcagtt
     9481 cttgcgcttg gataatatct tgcagaacta tgatgatttc atgagtttgc aggctttgca
     9541 agagttagat gttacagata tagaggcttt ggcagatttc aaaggacgtt ttcatttgga
     9601 tgacgaagca gttgcagtac tctctcaact ggacatccca agtgttcgtg agattcaaga
     9661 ttatcgctcc gcttacaatg atatcaagtc ttggtatgac aatgagcggc gtaatcagca
     9721 gaataacgat tccgaaatcg actgggatgc ggttgtcttt gaagtggagt tgttgaaatc
     9781 acaggaaatc aatctggact atattctgga attgattttt gaaaccaacc aaaaggtatc
     9841 tgacaaggat caactcattg aagaaattac acgaactatc cgtgctagtc tgggtcagag
     9901 agctaaggaa agtttgatcg tggattttat caatgccagt gacttggaca gtttttctga
     9961 gaagtcagat atcttggagc aattttatac atttgcccgt caaaaacaaa aagaagcagt
    10021 ggctaatttg attgagactg agggattgaa tgtagagagt gctagccgct atattcagat
    10081 gtcactcaaa cgagagtatg ccagtgaaaa tggtaatgct ctcaatgaag cacttcctaa
    10141 gatgagtccg ctcaatcctc aatatcgtac caaaaagcag atggtgtttg aaaaaattgt
    10201 ggatttggtg gagatattta aggggattgg tggagaaatt taattattat
//
LOCUS       DARYXW010000070         9897 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.070, whole genome shotgun sequence.
ACCESSION   DARYXW010000070 DARYXW010000000
VERSION     DARYXW010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9897
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.070"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            8..448
                     /locus_tag="TV191_001466"
     CDS             8..448
                     /locus_tag="TV191_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEL1507967.1"
                     /translation="MPSWKDLPDLELYLDQVLLYVNQVTQLSQATDHKLLTASMINNY
                     VKHGYIDKPIKKKYQKKQVARLIAISILKNVFPIQDISQVLTSLQAASSSEVLYDTFV
                     NYWNNGLTQSTPEIISYACQTVKDYQHTMKLSREMEDTKHEPNL"
     gene            432..1082
                     /locus_tag="TV191_001467"
     CDS             432..1082
                     /locus_tag="TV191_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEL1507968.1"
                     /translation="MNQTFKQSLPLSVNEEVANSVTHAIGAAAMLILLPITAIYSYQT
                     YDLKAAVGASIFIISLFLMFLSSTIYHSMSYGTTHKYILRIIDHSMIYIAIAGSYTPV
                     ALSLVEGLLGYVIIILQWGITLFGILYKIFAKTINEKFSLALYIIMGWLVVFILPVII
                     QKASLPFGILMLLGGLSYTVGAGFYAKKKPYYHMIWHLFILLASALQVIAIIFYML"
     gene            1192..2096
                     /locus_tag="TV191_001468"
                     /pseudo
     CDS             1192..2096
                     /locus_tag="TV191_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515585.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            complement(2449..2724)
                     /locus_tag="TV191_001469"
     CDS             complement(2449..2724)
                     /locus_tag="TV191_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507969.1"
                     /translation="MKKSYGIGLGLLLGSAAIAVTYLSLSSAKKKELLKEGSETIEEL
                     NHYIQEKGGQLIETASDKVEASKVAANACGHSAAKAIKGTLEEAIKI"
     gene            complement(3147..4697)
                     /locus_tag="TV191_001470"
     CDS             complement(3147..4697)
                     /locus_tag="TV191_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEL1507970.1"
                     /translation="MSILEVKQLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGHLQPDAGKIEWSKYVTAGYLDQHTVLEPGQTVRDVLRTAFDELFKTEERIN
                     AIYMSMAEETADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMETEVT
                     SLSGGQRTKILLAKLLLEKPDILLLDEPTNYLDAEHIEWLKRYLQHYDNAFVLISHDI
                     PFLNDVINIVYHVDNRNLVRYSGNYDQFKEVYEMKKAQLEAAYERQQKEIAELQDFVN
                     RNKARVATRNMAMSRQKKLDKMEIIELQAEKPKPSFEFKEARTPSRFIFQTRELVIGY
                     DRPLTKDPLNLTFERHQKVAIIGANGIGKSTLLKSLLGIIQPLSGEVETGDFVELGYF
                     EQETAGVKRQTPLEAVWDAFPALNQAEVRAALARCGLTSKHIESQIQGLSGGEQAKVR
                     FCLLMNREHNVLILDEPTNHLDVDAKEELKRALQVYKGSILMVCHEPEFYEGWVTDIW
                     DFNQLTSL"
     gene            complement(5368..5928)
                     /locus_tag="TV191_001471"
     CDS             complement(5368..5928)
                     /locus_tag="TV191_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL1507971.1"
                     /translation="MTSKRLTDQIELSLFAALIFISVELLRIPVGAQFIHLGNALVVV
                     AVLLYGARRAALVAAIGLGLFDMINGYAAVVWITVLEALVVCYLLHVIYEKLLKSVDK
                     PMIIVAIGLLAAAAKLVMNLVKYSLIAYFGAQLPLSVALWAALGKIGGSLGTALVTVI
                     AVPLLYPVFKQLRQAVKKQEASNRLG"
     gene            complement(5906..6775)
                     /locus_tag="TV191_001472"
     CDS             complement(5906..6775)
                     /locus_tag="TV191_001472"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HEL1507972.1"
                     /translation="MLKRVIVANDIVGVGKVALSASIPIMAACQIEQAILPTCLLSSH
                     TAIAKTPYIQSTSEGLKPFLTTWSQAGLAFDGFFSGYLYRPDDALIILDYIKKQQLPF
                     VLDPIMADKGSMYAQLTSQHLSAMRLLAQAAQLILPNVTEACLLADVPYFGETYSRED
                     LERLLSKLATLGPREIVLTGISFDDQHIGFAYYQKATETVSYHFGKRYPYHFYGTGDL
                     VSAIVSAGYFHRLAIDELLDMVISFLDKSLAATVALNRELSLGIAYEVELGSLGAAFR
                     GLLEEKDDIKTID"
     gene            6867..8138
                     /locus_tag="TV191_001473"
     CDS             6867..8138
                     /locus_tag="TV191_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEL1507973.1"
                     /translation="MTSKYQQIIADLELAMQSNQFKKGEKLPSIRQLSQQYHCSKDTV
                     QRALLALQYKRLIYAIPKSGYYVLGKIEEKQHSFELSLEDYNQLAYEDFRLCLNEALD
                     GKDSDLFNYYHKAEGLEELREALLPYLADNGIYANKNQLLITSGTQQALYILAQMRFP
                     NGRHHILLETPTYHRMEQLATSLGLPYQTIERDVNGINLHQLESIFKTGQIAFFYTIS
                     RFSNPLGLSYSKKEKESIVRLAEQYQVYIVEDDYLGDFASHSELPLHYYDTQHRVIYL
                     KSFSMSVFPALRIGALLLPDDLKEGFLLQKSMIDLDTNLIMQKALALYLANGMFQKNL
                     KQMRQFFNNRAHNLLDFLQKHLPNLAYQLTPQALIIQLDKAFNRKKLLKPHHTQIIST
                     RKARYMLLTISPDMPSKLLDLFSVTHEKTQE"
     gene            complement(8174..8512)
                     /locus_tag="TV191_001474"
     CDS             complement(8174..8512)
                     /locus_tag="TV191_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507974.1"
                     /translation="MQIIKRDGQLADFDPDKIYQALIKAARTVYVIDDSWRQHLAQVT
                     KKVVIDLEEVQAERPTINMIQSLVENRLIDAGYMTIAEHYIAYRLQRDLERNGYGDSI
                     SVHLRFEQIK"
     gene            complement(8612..9700)
                     /locus_tag="TV191_001475"
     CDS             complement(8612..9700)
                     /locus_tag="TV191_001475"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEL1507975.1"
                     /translation="MGYTVAVVGATGAVGQQMIKMLEESSLPISAIKLLASARSAGKI
                     LSFKGEDFVVEELTKAAFQGIDLALFSAGGNVSAKYAPYAVAAGAVVVDNTSYFRQHP
                     AVPLVVPEVNAHALDTHQGLVACPNCSTIQMMIALEPIRQRWGLERIIVSTYQAVSGA
                     GQSAIRETLAQYDQVINQGLSPKEVEASVLPSAGDKRHYPIAFNALPQIDRFTENDYT
                     YEEMKMTNETKKIMEDDTIKVSATCVRIPVLSAHSESIYIETKAVATIEAVKEAIAQF
                     PGAVLEDDTGVQRYPQAVNAVGSRETFVGRLRKDLDVEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPAQDNLFDPSVSFD"
BASE COUNT         2994 a         2228 c         1787 g         2888 t
ORIGIN      
        1 tgataagctg cccagctgga aggatttacc tgatttggag ttatacttag atcaagtgtt
       61 actctatgtc aatcaggtca cacaattgag tcaagccaca gaccataagc tactgactgc
      121 ttcaatgatc aataactatg tcaaacatgg ctatattgat aaacctatta agaaaaaata
      181 tcaaaaaaag caggttgccc gcttaattgc tattagcatt ttgaaaaatg tatttcctat
      241 tcaagatatt agtcaggtct tgacgagcct acaagcagcc tccagctcag aggtcttgta
      301 cgataccttt gtcaactatt ggaataatgg ccttacccaa tcaacgcctg aaattattag
      361 ctatgcttgt caaaccgtca aggactatca gcacacaatg aagctttcaa gagaaatgga
      421 ggataccaag catgaaccaa acctttaaac aaagtctccc actatcagtt aatgaagagg
      481 tcgcaaatag tgtgacacac gctattggag cagctgctat gctgatactg ctacccatca
      541 ctgctattta ctcttaccag acttatgatc tcaaggctgc cgttggagca tctattttta
      601 tcatcagctt atttctcatg tttttatcat caacgattta ccattccatg tcctatggaa
      661 caactcacaa atacatttta cgtatcattg atcatagcat gatttatatt gctattgctg
      721 gtagctatac acctgttgcc ttatccttgg ttgagggctt gttgggctat gtgattatca
      781 tactccagtg gggaatcaca ctttttggga ttttgtataa aatttttgct aaaacgatta
      841 atgaaaagtt cagtcttgcg ctttacatta ttatgggctg gttggtcgtt tttatcctgc
      901 cggtgattat ccaaaaggcc agtctgccat ttggaatctt gatgctacta ggtggcttat
      961 cctatactgt cggcgcaggc ttttatgcta aaaagaagcc ctattatcac atgatctggc
     1021 acctttttat ccttttagcc tctgctttac aggttattgc cattattttc tatatgctgt
     1081 aaaaagtagc tgttgctact ttttaaacgc gagcgcttgc ttacccccag acacctggct
     1141 tgattcatgc tataataaag ggcagtaaat agttgaaggg atcaaagcaa tatgaaaacg
     1201 gtacatattt tttacaatcc taattcagga aaaccagaaa atgacctggc tgaaaaggtc
     1261 aagcattatc tgattcaaaa tggtttttct gaagacaagg ttcagattat tacccccaaa
     1321 aatgctgatc aagcctttca attagccaaa aaatcctcac aggatcatat tgatctagtc
     1381 attcctctag gcggagatgg gacacttaat aaaattattg gaggtgttta tgaaggtggt
     1441 gctcattctg ttattggact cgtaccgtcg ggcactgtca ataactttgc aaaggcctta
     1501 aacattccac tccagctaac tgaggcactt gagacgattt tatctggcac gattaaaaaa
     1561 gtagatattt gcaaggtaaa caagggctat atgatttcta gcctaacctt gggtctgctt
     1621 gctgatattg cggctaatgt gactacagaa gaaaaacgaa aatttggccc ttggcctttt
     1681 taaaggatag tattaagata ctaaaacgaa accgcacata tgcaattagc ttaattagcc
     1741 atcatcatgt tcttcacttg aaaaccaaat tcttattgat taccacaacc aatactatag
     1801 caggtcttcc atcgttttca ccaggtgcac aagctgacga tggcttgtgt caagtttaca
     1861 cgatgagcca gctatcattt ctgaaatgct tgcgccatat tagagacttt agacgggggg
     1921 atttttccaa ggtaaaggag attagccatt ttcaagctga ttctctaaag ctattgccac
     1981 aatatcagcg tcaatcagcc attcctagaa ctcgcattga tggcgataag gctgatgatc
     2041 tccctgttga attgaaggtt attccaaaag cgatttccat tattgttagc cagtaaaaaa
     2101 gtgccctagg gcactttttg atatagattc atctccaagc tgagttttag aaaactaagc
     2161 tatagctata acgttagctg tggcttcttc ttgctggctt gcagtactct tttcttgtct
     2221 taacagctag ctctttcata atatcggctt taacaaagaa gctatctgac tagtccgatc
     2281 ttctattctc aggacaaaca gcgagaaagg ggattttctt tgaatcctag agaaccttag
     2341 ctatctctgt gtctcattgt aagtgcagct ctattgactg atgccagcta tagcaataag
     2401 cccagtcgca tattataaag gattatcagg cgatttagct tgacactctt atatctttat
     2461 tgcttcttct aaggttcctt taatagcttt agctgctgaa tgaccacagg cattagcagc
     2521 aaccttagag gcttctacct tatcagaggc tgtctcaata agttgtccac ccttttcttg
     2581 gatataatgg ttcaactcct caatagtttc agagccttcc tttaagagct ctttcttttt
     2641 ggctgaggat aagcttaaat atgtcacagc aattgctgct gaaccaagaa gtaatcctaa
     2701 gccgattcca tagctttttt tcatcatcaa ccctactttc tatgaccttc cttaatcatc
     2761 tttttagcta attttacagc tggtactact aaaagcacca attgtaaaag atccatatac
     2821 ttgatttttc gtcgtttttt caccatgtgc tatttccttt ttcttgtttg caccatacaa
     2881 tcgtctttta ttgcgcagtg ccagagactg cctgattagg cagcgtaagc taagaactat
     2941 cagcgtgtca gactagtcta gatacagcta agcactagct tgattacgat aatacttacc
     3001 gctaggccat aagctcagct atcatcaaat ctaaagtgac aacgcttttt atttattata
     3061 ttgtcatttt actaaaatac acaattatcg tcaatgcttt tgctttaggc agcaaaaatg
     3121 cccaagataa agaccttgga catctgctac aatgacgtta attgattgaa atcccaaata
     3181 tcagttaccc agccctcata aaactccggc tcatggcaaa ccatcaaaat agagccttta
     3241 tagacttgca aggcgcgttt taactcctcc ttagcatcta catctaaatg attggttggc
     3301 tcatctagga ttaaaacatt gtgctcacga ttcattaaga gacaaaaacg aaccttggct
     3361 tgctcaccac ccgagagccc ctgaatctgg ctttcaatat gcttagaggt tagaccgcaa
     3421 cgagctaagg ctgcccgaac ctctgcttga tttaaagcag gaaaagcgtc ccatactgct
     3481 tctagtggcg tttgacgctt aacacctgca gtttcttgct caaaataacc aagctccacg
     3541 aaatctcctg tttccacctc tcctgacagt ggctgaataa tgccaagcag gctctttagg
     3601 agggttgact taccaatacc attagcaccg ataattgcaa ctttttgatg acgctcaaat
     3661 gttaagttca agggatcttt tgttaggggt ctgtcatagc cgatgacaag ctcccttgtt
     3721 tggaaaataa agcggcttgg tgttcttgct tccttaaact caaagcttgg ctttggtttt
     3781 tctgcctgaa gctcaatgat ttccatttta tcaagcttct tttgacggga catagccata
     3841 ttgcgagtag ctactctggc cttattacga ttgacaaaat cctgtagctc tgcaatctct
     3901 ttttgctgac gctcataggc tgcctctagc tgagcttttt tcatctcata gacttcctta
     3961 aactgatcgt aatttccaga atacctaacc aaattccgat tatcaacatg ataaacaata
     4021 ttaatgacat catttaaaaa aggaatatca tgtgaaatga gcacaaaggc attgtcataa
     4081 tgctgtaaat agcgctttaa ccactcaata tgctcagcat caagataatt ggtcggctcg
     4141 tccagcagca aaatatctgg cttctccagt aacagcttgg ccagcagaat cttggttctt
     4201 tgccctccag ataaggaggt cacttctgtt tccatcccaa aatccataac tcctaaggca
     4261 cgcgcaacct catcaatctt agcatctagg gtataaaagt ccctgctttc aagacggtcc
     4321 tgtagctctc cgacctcctc cattaaggcg tcgacatcag ctgtctcctc tgccatagac
     4381 atgtaaatgg cattgatacg ctcctctgtt ttgaatagct catcaaaggc tgtcctaaga
     4441 acatcacgca cagtttgacc aggttctaaa acggtatgct gatccaaata gcctgctgta
     4501 acatactttg accattcaat cttaccagca tcaggctgca agtgaccagt aacaatactc
     4561 ataaaggtgg acttgccttc tccatttgct cctactaatc caatatgctc gccctttaaa
     4621 agacgaaagg aaacatcttc aaaaatggca cgatcaccaa atccatgact taactgctta
     4681 acttctaata tgctcatgat tactttcctt tattgtcatc aaaaaagccg ttaaaacggc
     4741 ttacactctc tcaattatgg caaaaatgca gccttttgtc aatgaaggct gaaaaagcct
     4801 acgtcatacg catgaaagat ttttagcaag aacagaaggt tttttgcatt ttaatgttca
     4861 gctatttcaa atatgtctta ttattttata aattttacta tagggaaagc cttgaaagtg
     4921 cctgctttaa tttatactat cattcggaaa gaactgtttc gctcgtttgt tgtggaaagc
     4981 cgctcacaac aaagacatag agagtctatg acaacaagag ctacacttta gcaagtcttg
     5041 accgacatgc tttattgccc agtctaattc attaaaaagc gaacaggtct agctttcgga
     5101 atttcagaaa actaggcctg ttcatttgtt ctattttgag gcagcctttt gtttcggcct
     5161 cgtctgtttc aaggttttca gatcgaactt aaggacaaaa aacactctcc tgtatcagct
     5221 aaccttatca ttcattataa aggaaaatga tttctaatac aaggaaatac cgttatttca
     5281 ttaaaaataa ctaaaaatag tttgtcaaat cattagttat taataggctt agataacaaa
     5341 aatgatgata ctgctagcaa ggttagctca accaagccta ttactcgctt cttgcttttt
     5401 tactgcctgc cttaattgct taaaaacagg gtataagaga ggcacagcaa taacggtcac
     5461 aagggcagta ccaagactgc caccaatttt gccaagtgct gcccacaaag caacagacag
     5521 gggtaactgg gcgccaaaat aagcaatcaa gctatatttc acaagattca tgactaattt
     5581 tgctgctgct gctaataagc caattgctac aataatcatc ggtttatcaa ctgatttcag
     5641 aagtttctca taaatcacat gaagcaggta acaaaccact aaggcttcaa gcactgttat
     5701 ccagaccaca gccgcatagc cattaatcat atcaaacagt cctagaccaa tggctgccac
     5761 caaagctgcc cttctagcac catacaataa aacagccacc accactaagg cattccctag
     5821 gtgaataaat tgggctccaa ctggaatacg cagcagctca accgatataa aaataagagc
     5881 agcaaatagg ctaagctcga tctgatcagt caatcgtttt gatgtcatct ttttcctcca
     5941 ataatcctct aaacgcggct cccaagctgc ccaattctac ttcgtaggca attccaagtg
     6001 aaagctctcg atttagcgca acagtagccg ctaatgactt gtctaagaag ctaataacca
     6061 tatccaacaa ctcatcaata gcaagcctgt gaaaataccc agcgctaaca atagcagaga
     6121 caagatcacc tgtcccatag aaatgataag ggtaccgttt tccaaaatga tagctaaccg
     6181 tctctgttgc cttttgataa taagcaaagc cgatgtgctg atcatcaaag gatataccag
     6241 taaggacaat ctctctaggt cctagtgtag ctagcttaga caatagcctc tccaaatcct
     6301 ctctgctata ggtctcccca aaataaggaa catcagctaa caaacaagct tccgtcacat
     6361 ttggcaatat cagctgtgca gcttgagcga gcaatctcat tgccgataag tgctgcgagg
     6421 ttaactgcgc atacatgctt cccttgtcag ccataatagg atctagcaca aagggaagct
     6481 gttgcttttt gatgtaatca agaataatca aagcatcatc aggacggtac aaataaccgg
     6541 aaaaaaagcc atcaaaggca agacccgctt gagaccaagt cgtcaaaaat ggctttagtc
     6601 cctctgacgt gctctgaata taaggcgtct tagcaattgc agtgtggctt gataacaaac
     6661 aggttggaag aatggcctgt tcaatctggc aagccgccat aatgggaata ctagcagaca
     6721 gagcaacctt gccaactccg acaatatcat ttgcaacaat aacacgtttt aacaaccaat
     6781 aagctccttc atttcttttt ttactattgt aagaaaatcc ttgatgagat acaataagga
     6841 tagatttcat ctgtatgggg acacttatga caagtaaata tcaacaaatc attgcagacc
     6901 tagagttggc catgcaatca aaccaattca aaaagggaga gaaactccct tctattagac
     6961 aattaagtca acagtatcac tgcagcaagg atacagtgca aagagcactt ttagccttac
     7021 aatacaagcg cctcatttat gctattccaa aaagtggcta ttatgtgctt ggtaaaattg
     7081 aggaaaagca gcattccttt gagctaagcc ttgaggatta taatcagttg gcctatgagg
     7141 actttcggct ctgtctaaat gaagccctag acggtaaaga ttctgattta tttaactact
     7201 atcataaggc tgagggactt gaggagctgc gagaggcttt gctgccttat ttggctgata
     7261 atgggattta cgctaacaaa aatcagctgc taattacctc gggtacacaa caggcccttt
     7321 acattttagc tcaaatgaga tttcccaatg gccgccatca cattctcctt gagacaccga
     7381 cctatcaccg aatggagcag ctagcgactt ccttaggctt accctatcaa accattgaac
     7441 gtgatgtcaa cggtatcaat cttcatcagc ttgaaagcat ctttaaaacc ggacaaatcg
     7501 cttttttcta tactatttct cgattttcaa accctcttgg cctctcctac agcaaaaaag
     7561 aaaaggaaag cattgttcgg ctggcagagc aataccaggt ttacatcgta gaggacgatt
     7621 atctagggga ctttgcatcg catagtgagc ttccgctaca ctactacgac actcaacacc
     7681 gggtcattta tctgaaatca ttttcaatga gcgtctttcc tgccctgcgc attggagcct
     7741 tgcttttacc tgatgatctc aaggaaggct ttttgttaca aaagtcaatg attgaccttg
     7801 ataccaacct gatcatgcaa aaggcactag cattatattt agcaaatggt atgtttcaaa
     7861 aaaacctaaa gcaaatgagg caatttttca acaatagagc gcataactta ctagattttc
     7921 tacaaaaaca ccttcctaac ctagcttatc agctcactcc tcaagcactg attattcaat
     7981 tagataaagc attcaatcgc aaaaagcttc ttaaaccaca ccacacccaa atcatctcaa
     8041 caagaaaagc aaggtatatg cttctaacaa tcagtcctga tatgccatct aagctgctcg
     8101 acttgttttc agtgacacat gaaaagaccc aagaatagct cattgggtct cagtgtcaca
     8161 aaaatgtcaa tagctatttg atttgctcga atcgtaaatg aacactaatg ctatcgccgt
     8221 aaccgtttct ctccaaatct ctttggagcc ggtaagcaat ataatgctct gcaatagtca
     8281 tgtagcctgc gtcaatcaga cgattttcaa caagtgattg aatcatatta atcgtcggac
     8341 gctccgcctg cacctcttct agatcaataa caaccttttt agttacctga gctagatgct
     8401 gtctccagct gtcatcaatc acataaactg ttcttgctgc cttgatcaaa gcctgataaa
     8461 tcttatccgg atcaaagtct gccagctgac cgtcacgctt aataatttgc ataagagcgc
     8521 ctcttttcat ttagtttcat tgcttacatt cattatgcaa atgttttcat catttgtcaa
     8581 gctattaggc tcctatgcct cttagggatt atcagtcaaa agaaacacta ggatcaaata
     8641 aattgtcctg tgctggtcgg acaagcccac gctcgtgcaa ggtctctgca atctgaacag
     8701 aattccaggc tgcgcccttg agcagattgt cagataccac ccacatgtga atgccctttt
     8761 caacatctaa atccttacga agccttccta caaaggtctc acgactgcca acagcattaa
     8821 cggcctgtgg gtatcgttgc actccggtat cgtcctctaa aacagcaccc ggaaattgtg
     8881 caatcgcctc cttaacagct tcgatagtag ctactgcctt ggtttcaatg tagatagatt
     8941 ctgaatgggc tgataaaacg ggtatacgaa cacaggtcgc agacacctta atcgtatcgt
     9001 cctccatgat ttttttcgtt tcatttgtca ttttcatctc ttcataggtg tagtcatttt
     9061 cagtgaaacg atcaatctgt ggtaaagcat taaaagcaat tggataatgt ctcttgtcac
     9121 cagctgacgg taaaacactt gcctccacct ccttaggaga caagccctgg ttaataacct
     9181 ggtcatactg agctagggtc tcacgaatcg ctgattgacc agcacctgaa acagcctgat
     9241 aggtggaaac aataatacgc tcaagacccc acctttgacg aataggctcc agcgctatca
     9301 tcatttgaat cgtagagcaa ttagggcaag caacaaggcc ttgatgtgta tcaagagcgt
     9361 gagcatttac ctcaggaaca acaagtggaa cagctgggtg ctgacgaaaa taagaggtat
     9421 tgtcaaccac aacagcacct gccgcaacag cataaggggc atattttgca gaaacattgc
     9481 ctcctgctga aaaaagggct agatcaatgc cttggaaggc tgcttttgtt agctcctcaa
     9541 caacaaaatc ctctccctta aatgagagga tttttcctgc tgaacgtgca gacgctaata
     9601 atttaatagc tgaaataggc agacttgact cctccagcat cttaatcatt tgctgaccga
     9661 cagcgcctgt cgctccaacc actgctactg tataccccat agatcgacct cactttaact
     9721 gatgatattg caaaaaatga tattggacct attatagcct atttcatcac aaaagaaaag
     9781 caagctagaa gccagaacaa acgcatgaag aaaatcattt attgaaaaag ttgtgaaaat
     9841 agcaaaatat ccattttaga gtattttgac agagtgtttc ctgaattttt atatttt
//
LOCUS       DARYXW010000071         9750 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.071, whole genome shotgun sequence.
ACCESSION   DARYXW010000071 DARYXW010000000
VERSION     DARYXW010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9750
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.071"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            161..325
                     /locus_tag="TV191_001476"
     CDS             161..325
                     /locus_tag="TV191_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin S family TOMM toxin"
                     /protein_id="HEL1507976.1"
                     /translation="MLQFASNILATSVAETTQVAPGGCCCCCSCCCCVSASWGNTTIN
                     NNYGAAEPKA"
     gene            553..1503
                     /locus_tag="TV191_001477"
     CDS             553..1503
                     /locus_tag="TV191_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="HEL1507977.1"
                     /translation="MPFFSKEKQRSDNQSDLTREEARQLFEFNTNHLSLSTYHHQTVL
                     KTSKQLVAQHLMPDETDNLSQRFLMNYKANNNYLGFKTSVAEFFTDSAVTTFSNSDYF
                     EDRANTIALPKAKKVSAALSTCITNRRSHRQFIDEEMPLQDLADLLYYACGVSSQAII
                     KEGMTKTVALRNCASGGGLYPITLFFYARNVETLKDGFYEYLPYQHALRCHHLSDQED
                     IRAFAEYGPITAENCNVILIYVYQYIKNTRKYGNQATAYAFIEAGEIAQNVQLVSTAL
                     VYGSVDIGGYNKEYLQEKLGLDGLTQHVIHMTIIGNKESQ"
     gene            1500..2564
                     /locus_tag="TV191_001478"
     CDS             1500..2564
                     /locus_tag="TV191_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagC"
                     /protein_id="HEL1507978.1"
                     /translation="MKYQLNSNVRIVQFDDTFCFRKGLWDFNEAVLDIAQEPQALKEA
                     YYSIISDWFNGKVIDTDTYEKTLESDLFAKLSEVITALYYNDLLMLEDAYALEENIMK
                     VLTGNYHFIAESGQAKDTAPVLFISDSSYVNESAELLAKHLNLNLQVASDELKMLIQE
                     TDVTSRLDALEHHRNMKCLSEKLADYQSIVICQGRLNIMMLRHLNEISVALKKQLVLG
                     FVDGPFIHACTLNPPHSADFDSLERRVLARLQDHTLYQRFASQQLPPTQPVSSSYVPL
                     LNVLMNLVVSEAFIIAQTGSSKFEGRLLSVYLPTLEIQVQDILKMSNSQTQGALTKLR
                     YEDQQISTREIVKKLLQEES"
     gene            2577..3935
                     /locus_tag="TV191_001479"
     CDS             2577..3935
                     /locus_tag="TV191_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaO-like family protein"
                     /protein_id="HEL1507979.1"
                     /translation="MLHYYPSFNHILDKLKGLSGNRTGILNQSQVPICNHPHDVYLKS
                     VTGQMPDYHKQFIGELSQVSYHIIGYGSHYEEALIKYLGESIERYATVIAGELLSDRI
                     VYASYKELSQTDPVMPLEYLQVFTQEQIDRCHDLHMIMCDKMVTQDDVLGWVKCPMFF
                     EDKEMYVPAQMLCVGYKTNQAVGEKHIIPGFSTGTASHTTLEAAMCNSLIEYIQIDSM
                     MLSWHTKKPCPRVIIDDPEILALLEEARLGKDSLYEIIPIDMTVGEDNPLYTFGIILK
                     NKSNEGPYLLFGVQAGLDPKHTLLRGIMEASAISYSYYYNLFYNPTSTQNAESDSPLF
                     LDLDSNVFYYAHPKDQELKWKAFEPLISGEVRLSDLTNHAGKDKKEDLKTLLAYTKKV
                     SPNAVFLDITPPEASEKGWYVTRVLTPELLEMCIPAFPFANHPRMRQFGGVTNAFVHP
                     MP"
     gene            3910..4581
                     /locus_tag="TV191_001480"
     CDS             3910..4581
                     /locus_tag="TV191_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEL1507980.1"
                     /translation="MPLYTQCLNLCFLMATFCPSIAMQAIFGQGRDSYSFNLIGFLRA
                     VLVYYALVLTGIYLLSPPIKAPLGHSDGRLLIIGFILSFVVLFVEVAFLHLSRCWQKK
                     EWLPLVLSFVGTTQKWPQIGYPLVLACCEEITYRLIWFNILWLQWRLPIALVLLITSL
                     CYALNHFLMGRSIFYAKILTGLIYGSIYYVSQSLWLVLLVHVGGNLWVEGLSHLQSMH
                     KKVVR"
     gene            4578..5264
                     /locus_tag="TV191_001481"
     CDS             4578..5264
                     /locus_tag="TV191_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagF"
                     /protein_id="HEL1507981.1"
                     /translation="MIIILALLSFLILVTLFLTSHKRRRLVRWHLRHIRAMSYQQWLD
                     LLLGLIQLGLVLVCLLFSDALALDGLLTFLGRVSFGWEIICYVLLYSIALVELTLLVL
                     VLLFDLMLKKDSRLLLGKMTWLAFKPDRAAASFLLLSLVTLVDAFCYLGLCLFLGKDS
                     VAGLTLVVLGYALVKACRYSGWLQQLLALCLFSVIGVWCVTAALLYGWLIGSLLLTLT
                     YLLISFKEQR"
     gene            5287..6210
                     /locus_tag="TV191_001482"
     CDS             5287..6210
                     /locus_tag="TV191_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1507982.1"
                     /translation="MSFVELKDVVKVYRGGKKAIDHVSLTIEEGRIYGLLGPNGAGKS
                     TLINAILGLIPLNAGEVTVLQQSYKSIRKISSKIGYVPQDIAVYPDLTAYENVELFGS
                     LYGLKGSELKEQVLKSLEFVGLKSQASQFPSQFSGGMKRRLNIACALVHSPKLIIFDE
                     PTVGIDPQSRNHILESIRLLNEQGATVIYTTHYMEEVEALCDYIYIMDHGQVIEEGSQ
                     AELERRYESDFTKQIMVTVAADQAIDLSNKPNWRLMDNELEAVLLIEHEDIGSVVRQL
                     TDAHIAFSEIRHKHLNLEEIFLHLTGKKLRD"
     gene            6219..7346
                     /locus_tag="TV191_001483"
     CDS             6219..7346
                     /locus_tag="TV191_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1507983.1"
                     /translation="MILFHLIKKESLQIFRDRTALLMMVVFPILMILILSFAFKSSFN
                     TAATVPKLTVRYQLEGKETEYQKNFITFLKLLNKELHLEAKETKDIAKAKQKVSEGAL
                     TAALEVKSDQNIEVTTNSINQQNADLINMLVNIYVDNAKTYDSIANLYPEAISNIKKR
                     KIDYIASSSVQTSKGMSSADYYAISMFTMITFYSIMSAMNLVLSDRQQGVASRIYLTG
                     VSNSAILLGKLIGGMLATAVQLTILYVFTRFVLRVNWGTNDWQIIGVTASLVYLSVAI
                     GIGLATGIRNQSFLTVASNAVIPVFAFLGGSYIPLSTLNSALINQLSNISPIKWVNDS
                     LFYLIFGGQSNPIPVTLMVNLGIGTAFILFALVRMRKQVAA"
     gene            7343..8461
                     /locus_tag="TV191_001484"
     CDS             7343..8461
                     /locus_tag="TV191_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1507984.1"
                     /translation="MIPFIKALFIKIRRKKTSYITFILLPMLTTMLALSLSFTGGSQA
                     KIGILDKDKSQVSKQFVSQLKHNKKYQIYTRLEEKAIDQYLKAKTLEAVLTIEPGFGE
                     KVLKGDTQKIALRSIADSQITEWFKAQANYLLENYNIIGDAAAGNQEVFKKISAHNTK
                     LSYKVKEITLADRSQSKSVSSTTTGFLLILMLGSTSVLYGGILLDKSSQIYNRLVLSR
                     LSSLQYMLSYVCVGIVAFAIQIVIMLGLLRVANVSFYIPTAIVLLTFFLYSLLAIGFG
                     LMIGAVSKNAQQSSQLANLIVMPTSMLAGCLWPLSITPPYMQAIGKLLPQHWVLTIIS
                     TFQNGGNLGEAWPYFLALFVAAMTLMVLASVLMKPLHR"
     gene            complement(8594..9685)
                     /locus_tag="TV191_001485"
     CDS             complement(8594..9685)
                     /locus_tag="TV191_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1507985.1"
                     /translation="MRKTMKKMLAASTVCIIMSGSFIGGAARVLAEQYYGYDDGTKDG
                     GDWPVFLYVTPTNHPERKTDKEHCVYCFNRLNSSPELWESQFKDPSKLGIKLPIYEKK
                     EGDESLLRAKSQKPSDNLTSKLVTVLSNGYPNKTLGNLSEDQSRRLTQLAIWHFTDGY
                     ATNHFKDGYHLNKDEDSELKKLIETAEKNFQTTAHTYSLNLYVTSSYNYSTGKFYQHL
                     LGSTLTPKLPNPNPGPKPPGGNNPHHLPGENGQTKYPEGESGEAGAPKKPEPKPEPKP
                     EPMPKPEPKPQPEPMPEPKPKPEPQPKPAPQPEVKPQKPTKPSNTTSQSSGKGLPRTN
                     EAGSLMTGLGTGLLSLLGLGFLTRRKRKD"
BASE COUNT         2633 a         1830 c         2146 g         3141 t
ORIGIN      
        1 gaattgaatg gtcactttaa caagggcgat acaaaatagc tagccttgtg ttgctggata
       61 cctgctcatg attgcttttg ctatcagttg agaggtattc tcatttaact cttatcagtg
      121 ttttgtttta ccgatcaggc gatataagga ggtaagcatt atgttacaat ttgcttcaaa
      181 tattttagct actagtgtag cagaaacaac tcaagttgct cctggtggtt gctgctgttg
      241 ctgttcttgt tgttgctgcg tctcagcttc atggggcaat actaccataa acaacaatta
      301 tggtgcagct gagccaaaag cgtaaacttt aatacttcta tttaatagtt aatagctagg
      361 tcacaatcat tagtttgcta gcgactaagg ttacagtttg taattgatgg tgttagctgg
      421 tgttggatag gggtgttaca tgacaagaga cgaagacaat cagcttgatg tcaacgtctt
      481 gtagtaatta gcaggtacta gtcggtacct gctaattact attatttatt aatatattac
      541 aggaagacag ttatgccatt tttttctaag gaaaaacaac gttcggataa ccaaagtgac
      601 ctaacaagag aagaagcacg acagttattt gaatttaata ccaatcactt atcgttatca
      661 acctatcatc atcaaacggt attaaaaaca tcaaaacagc ttgtggcaca gcatttgatg
      721 cctgatgaaa cagacaatct tagccaacgg tttttgatga attacaaggc taataacaat
      781 tacctagggt ttaagaccag tgtggctgag ttttttacgg attctgcagt gaccaccttt
      841 tcaaatagtg actattttga ggatagggca aacacgatag cacttcctaa agctaagaag
      901 gtctcagcag ccctatcaac ctgtatcacc aaccggagaa gtcataggca gtttatagat
      961 gaggagatgc ctttgcagga tttggctgat ttgctttatt atgcttgtgg tgtcagctct
     1021 caggcaatca tcaaagaagg catgactaag acagtagcct taagaaattg tgcttctggt
     1081 gggggtctgt accccatcac cttatttttc tatgcaagaa acgtagaaac actcaaggac
     1141 ggtttttatg aataccttcc ttatcagcac gcgctgaggt gtcatcatct tagtgatcag
     1201 gaggatatta gagcctttgc cgaatacgga ccgatcactg ccgaaaactg caatgtcatt
     1261 cttatctatg tttatcagta catcaaaaac acacgtaaat atggaaatca agctactgct
     1321 tatgccttta ttgaagctgg agagattgct caaaatgttc aattggtctc aacagctttg
     1381 gtatatggaa gtgttgatat tggagggtac aataaggaat acctccaaga aaagctaggc
     1441 ttggatggct tgacccagca tgtgattcac atgacgatta ttggaaataa ggagtctcaa
     1501 tgaaatatca attaaatagc aatgttcgca ttgtgcaatt tgacgatacg ttttgcttta
     1561 gaaaaggcct atgggatttt aatgaagctg ttttagacat tgcacaagag ccacaagcct
     1621 taaaagaagc ctactacagt atcatctccg attggtttaa cgggaaagtt attgatactg
     1681 atacctacga aaaaacacta gagtctgact tatttgcaaa attgtcagag gtcatcacag
     1741 ccttgtatta taacgaccta ttgatgcttg aagacgctta tgctcttgaa gaaaatatca
     1801 tgaaggtctt aacaggcaat tatcatttca tagctgaatc aggacaggct aaggatactg
     1861 cacctgtctt atttatcagt gattcaagct atgtcaatga atctgctgag ctgctggcca
     1921 agcacctgaa cttaaacctt caggtggcta gcgatgagct aaaaatgctc attcaagaaa
     1981 cagatgttac ctctcgctta gatgctctgg agcaccatcg caacatgaag tgcttatctg
     2041 agaagctcgc agactatcag agtattgtta tttgtcaagg ccggttgaat attatgatgc
     2101 tgcgtcacct taatgaaatc agtgtggcct tgaaaaaaca attggtgctt ggctttgttg
     2161 atgggccgtt tatccatgct tgtaccttaa atcctcctca tagtgctgat tttgatagct
     2221 tggagagaag ggtgctggca cgtttacagg atcacacgct ttatcagcgc tttgcaagtc
     2281 agcagttgcc gccaacacag cctgttagct cctcttatgt acctttgtta aatgtgttaa
     2341 tgaatctggt tgtcagtgag gcctttatta ttgctcaaac aggaagctca aaatttgaag
     2401 ggcgtttgtt aagtgtctat ttgccaacgc ttgagattca ggtgcaggat attttgaaaa
     2461 tgtctaattc tcagacacaa ggggctctga caaaattaag gtatgaggat caacagattt
     2521 caacacgtga gattgttaaa aaactccttc aagaagagtc ataaggaggt ctaaggatgc
     2581 tacattatta cccttcgttc aaccatattc ttgataagct aaagggcctt agtggtaacc
     2641 gaactggtat cttaaatcaa tctcaggttc ctatttgtaa ccatcctcat gatgtttact
     2701 taaagagtgt gacaggacag atgcctgact accacaagca atttattggt gagctgagtc
     2761 aggtgagcta tcatatcatt ggttatggca gtcattatga ggaagccttg atcaaatact
     2821 taggtgaaag cattgagcgt tatgccactg ttattgctgg ggaattatta tcagaccgga
     2881 ttgtttatgc ttcttataag gaattgagcc agacggatcc tgtcatgccc ttagagtatt
     2941 tgcaggtttt tacgcaggaa caaattgacc gttgccatga tttgcacatg atcatgtgtg
     3001 ataaaatggt gacgcaagac gatgtcttgg gctgggttaa gtgtccgatg ttttttgaag
     3061 ataaggagat gtatgtgcct gcccaaatgc tttgcgttgg ctataagacc aatcaggctg
     3121 taggcgaaaa gcacatcatt ccaggctttt caacggggac agcctctcat acaacgctgg
     3181 aagcagccat gtgtaatagc ttgattgagt atattcaaat cgactctatg atgcttagct
     3241 ggcatactaa aaagccttgt cccagagtga ttattgatga tccggaaatt ctagctcttt
     3301 tggaagaggc tagacttggt aaggacagtc tttatgagat tatccctatt gacatgactg
     3361 ttggagaaga taatccgctt tatacctttg gtattatcct taaaaacaag tccaatgaag
     3421 gtccttatct cttatttggg gttcaggcgg gcttggatcc taagcatacc ctgttaagag
     3481 gaatcatgga agcttcagct attagctata gctattacta taatttgttt tataatccaa
     3541 cgtcaacaca aaatgctgag agtgactctc ccttgttttt agacctagat agtaacgtct
     3601 tttactatgc tcatccaaag gatcaggagc ttaaatggaa ggcctttgag cccttgattt
     3661 caggagaggt tcgtcttagt gacctgacaa accatgctgg gaaagataaa aaagaggatt
     3721 taaagacact actagcctac actaaaaaag taagtcctaa tgctgtcttt ttagacatta
     3781 ctcctcctga ggcctcagaa aaaggctggt acgtgacacg tgtcctcact cctgagcttc
     3841 ttgagatgtg cattcctgcc tttccatttg ctaatcatcc acgcatgaga cagtttggag
     3901 gtgtgacaaa tgcctttgta cacccaatgc cttaacctat gctttttaat ggctaccttt
     3961 tgtccttcga tcgcaatgca ggctattttt ggccagggtc gtgatagcta tagctttaat
     4021 ctaataggtt ttttaagagc tgtactggtt tattatgccc tagtcttaac agggatttac
     4081 ctgctgtcac ctcctattaa agcgccctta ggtcatagtg atggtcgtct tttgatcatt
     4141 ggttttatct tgagctttgt tgtgctcttt gttgaggttg cttttttaca tcttagccgc
     4201 tgctggcaaa aaaaagagtg gcttccctta gtcctatcat ttgtcggaac gacacaaaaa
     4261 tggccacaga taggctatcc cttggttttg gcctgctgtg aggaaatcac ctatcgtttg
     4321 atttggttta acatcttgtg gcttcaatgg cgattgccaa ttgctcttgt cttgttgatc
     4381 accagcctgt gctatgccct aaaccatttc ctgatgggca gatccatttt ttacgccaaa
     4441 atactgactg gtcttattta cggaagtatt tattatgtta gtcagagctt atggctggtg
     4501 ttgcttgttc atgttggagg caatttatgg gttgaaggct tgagtcatct tcaatcaatg
     4561 cataagaagg tggtacgatg atcataatac tagcattgct atccttttta atcctagtga
     4621 ccctttttct aacaagtcat aaaagacggc gcttagtcag atggcattta aggcacatca
     4681 gggcaatgtc ctatcagcaa tggcttgatc tattgcttgg tctaatccag cttggtctag
     4741 tgcttgtttg tctattattt tctgatgctt tagctcttga tggtttgctg acctttttgg
     4801 gtcgcgtatc ctttggctgg gaaatcattt gttatgtgct attgtatagc atagccttgg
     4861 tagagctgac cctgttggtt ttggtcttgc tttttgatct tatgctgaaa aaggacagtc
     4921 gcctgctctt aggaaaaatg acttggctag cctttaaacc agatagggca gcagctagct
     4981 ttcttttgtt aagtcttgtc acactggttg atgctttttg ttacttaggt ctatgtctct
     5041 ttttaggaaa agattcagtg gcaggtctta cgcttgtggt tttgggctat gccttggtca
     5101 aggcctgtcg ttactcaggc tggctacagc agctactagc cctatgcctc tttagtgtga
     5161 ttggtgtctg gtgtgtgaca gcagccttat tatatggttg gttgattggt tcgcttttat
     5221 tgaccttaac ttatctgtta attagtttta aagagcagcg ttagagttgg aaagaaggaa
     5281 taatatatga gttttgtaga gttaaaagat gttgtcaagg tctatcgagg cggcaaaaag
     5341 gcaatagatc atgtctcact gacaattgag gaagggagaa tctacggcct tttagggcct
     5401 aatggcgctg gtaagtcaac cttaatcaat gctattttag ggttaatccc tttgaatgct
     5461 ggcgaagtga ctgttttaca gcaatcttat aaatctattc gaaaaattag ttccaagatt
     5521 ggctatgtcc ctcaggatat tgctgtttat cctgatttaa cagcctatga gaatgttgag
     5581 cttttcggct ctctctatgg cttaaaggga agtgagctca aggagcaggt tttaaaaagc
     5641 ttggagttcg tagggttaaa atcacaggca agccagtttc caagccagtt ttcaggaggt
     5701 atgaaaagac ggttaaacat tgcctgtgct ttggtgcatt ctcctaagct aatcatcttt
     5761 gatgagccga cggtagggat tgacccacag tctcgtaatc atattttaga gtctattcgc
     5821 ttgttaaatg agcaaggagc tactgttatt tacacgaccc actacatgga agaggttgag
     5881 gccttatgtg attacattta cattatggat catggtcagg tgattgaaga gggcagtcag
     5941 gccgagctag aaagacgcta tgagtctgat ttcacaaagc aaatcatggt gacagtcgca
     6001 gctgaccaag caatcgatct ctctaataag cccaattgga gactgatgga taacgagctt
     6061 gaagcagttc tcctgattga acatgaagac attggctcgg ttgttcgtca gctgacagat
     6121 gctcatattg cttttagtga gattaggcat aagcatttga atttagaaga aatcttcctg
     6181 catttgactg gtaagaagct aagagattag gggttgttat gatcttattt catttaatca
     6241 aaaaagaaag cttacagatt tttagggatc ggactgcttt gttgatgatg gtggtttttc
     6301 ctatcttgat gattctgatt ttaagctttg cttttaagtc cagctttaat acagcagcta
     6361 ctgttcctaa attgacggtt cgttatcagc ttgagggcaa ggaaacagag tatcaaaaga
     6421 actttatcac gtttttaaag ctgttaaata aagagcttca tttagaagct aaagaaacca
     6481 aggatatcgc taaggctaag caaaaggtca gcgagggcgc cttgacggca gctctagagg
     6541 ttaagagcga ccaaaacatt gaggtgacca ccaacagcat taaccaacag aatgctgatt
     6601 tgattaatat gcttgtcaat atctatgtgg ataatgccaa gacctatgat tcgattgcta
     6661 acctttatcc agaagccatt agcaacatca agaaaagaaa aatagactat atcgcctcta
     6721 gctctgtgca aaccagtaaa ggcatgagct cagcggatta ctatgctatt tccatgttta
     6781 ccatgattac cttttatagc attatgtcag cgatgaatct ggtgctatca gatcgtcagc
     6841 aaggggtggc tagccgcatt tatttgacag gggtctcaaa tagtgctatt ttgcttggaa
     6901 aattaattgg tggtatgcta gcaacagcag tccagctaac cattctttat gtctttaccc
     6961 gatttgtgtt acgtgttaat tgggggacta atgactggca gattatcggt gtgacggcct
     7021 cgctagttta tttgtctgtt gccatcggta tcgggcttgc gactggtatt agaaatcaat
     7081 cctttttgac ggtagcgtct aatgcagtca ttcctgtctt tgcctttttg ggaggaagct
     7141 atattccttt gtcaacctta aatagcgcct tgattaatca gctgtctaat atttccccga
     7201 taaaatgggt caatgatagt ttgttttatc ttatttttgg tgggcagtcc aatcccatac
     7261 cggttacctt aatggttaat cttggtatag gaacagcctt tatcctcttt gctttggtca
     7321 gaatgagaaa gcaggtggca gcatgattcc ttttattaaa gccttattta tcaaaattag
     7381 acgtaaaaaa acaagctata tcacctttat cctgttgcct atgctaacaa caatgctggc
     7441 cttgtccttg agctttacag ggggaagtca agctaagatt gggatcttag ataaggataa
     7501 gagtcaggtt tccaagcagt ttgtgtcgca attaaagcac aataaaaaat atcagatata
     7561 tactaggcta gaggaaaagg ctattgatca atacctaaag gccaagacac tggaggctgt
     7621 gctgaccatt gagccgggct ttggtgagaa ggttctaaaa ggagacactc aaaagatcgc
     7681 tctacgttcg attgctgata gtcaaataac agaatggttt aaggcgcagg ctaattatct
     7741 cttggagaat tacaatatca ttggtgatgc ggcagcaggc aatcaagagg ttttcaagaa
     7801 gatttcagct cataacacga agctatccta caaggtcaaa gaaatcaccc tagctgatcg
     7861 ttcccaaagt aagtctgttt cctcgacaac aactggcttt ttattgatcc taatgctagg
     7921 cagcaccagt gtcttgtacg gtggtatctt gcttgataag tccagtcaaa tctacaatcg
     7981 cttagtctta tcaaggctat caagccttca atacatgctg agctatgtct gtgttggtat
     8041 tgttgccttt gcgatacaaa tagtgattat gctgggatta ctcagggtag caaatgtcag
     8101 cttttacatt ccaacagcca ttgttttgtt gactttcttt ctttatagtt tgttagctat
     8161 aggctttggc ttaatgattg gtgcggtttc taaaaatgcg caacaaagca gtcaattggc
     8221 taatctgatt gtgatgccaa cctctatgct ggcgggttgt ttgtggccgc ttagtattac
     8281 gccgccttat atgcaggcga ttggaaagct actcccacaa cattgggtgt taaccatcat
     8341 cagcactttc caaaatggcg gtaatctagg tgaggcttgg ccttatttct tggccttgtt
     8401 tgtagcagcc atgaccttaa tggtactagc aagcgtgctg atgaagcctt tacatcgcta
     8461 gactaagttg tcttaccctt tttgaaccaa gcttaaaaag ccttatcgtt ccatttatgg
     8521 cgcgataagg cttttgtgtt gtattagact agatactgat caactaaacg actatagata
     8581 atcttttagt gtcttagtct tttcttttgc gtcttgttag gaagcctaat ccgagaagag
     8641 agagtaagcc tgttccaagt cctgtcatta gactgcctgc ttcatttgtt cttggtagtc
     8701 ccttgccgct agactggcta gtagtgtttg atggcttggt tggtttttga ggcttaacct
     8761 ctggttgagg cgctggttta ggctgaggtt ccggtttagg cttaggttct ggcataggct
     8821 caggttgtgg cttaggctct ggcttaggca ttggttccgg cttaggctct ggtttaggct
     8881 cgggcttttt aggagctcct gcctcaccgc tttctccttc tggatattta gtttgaccat
     8941 tttcacctgg taaatgatgt ggattgttcc cacctggtgg tttaggtcct ggatttgggt
     9001 tcggaagttt tggtgttaaa gtggaaccaa gaagatgttg ataaaattta cctgtactat
     9061 aattatatga tgaagttaca taaagattta agctataggt atgtgctgta gtttggaagt
     9121 ttttttcagc agtttcaatt aactttttta attctgaatc ttcatctttg tttagatgat
     9181 aaccatcttt gaaatgattt gtagcgtatc catcagtaaa gtgccaaata gctagctgtg
     9241 ttaatcggcg actttgatct tcacttaaat tacctaatgt cttattagga tagccatttg
     9301 aaagaacagt aactaatttt gaagttaagt tatcactggg cttctgagat ttagctctta
     9361 aaaggctttc atctccttct ttcttttcat agatagggag ttttatacct agcttacttg
     9421 gatctttaaa ttgagattcc cagagctcag gtgaactatt taacctgtta aagcaataga
     9481 cacagtgctc tttatcggtt tttctttcgg ggtgatttgt tggtgttaca tataaaaata
     9541 ctggccagtc tccaccgtct tttgttccat catcatagcc atagtactgc tctgccagta
     9601 ctcttgccgc gcctccgata aagctgcccg acatgatgat gcagactgtc gaggctgcta
     9661 gcatcttctt cattgttttt ctcatgtttc tctcctttga gtttagaaat agtcattccc
     9721 aaacctttct tctccgtaga atagcttaac
//
LOCUS       DARYXW010000072         9681 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.072, whole genome shotgun sequence.
ACCESSION   DARYXW010000072 DARYXW010000000
VERSION     DARYXW010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9681)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9681)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9681
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.072"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(<1..1217)
                     /locus_tag="TV191_001486"
     CDS             complement(<1..1217)
                     /locus_tag="TV191_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEL1507986.1"
                     /translation="MKKLIVTLAALMCLITNTSFAENFSVNSRQAIAVEMTTGKILYA
                     KEAQQKAPIASLTKLLTVYLVLKEIKAGRLQWDSQVTLSEYALQLATDPDISNPAFEQ
                     RPYTIKELVESSLIISANSSAVALAEHIAGSEPTFVDMMKKQLEAWGIRDYLLVNASG
                     LNNSMLKGHLYPGSQPDDENQMTARDLALIAQQLIQDFPELLTISSQPQLKWGEKALP
                     SSNLLLAGREMGRAGVDGLKTGTTSQAGQTMIATAVQDNMRVISVILHADQSDTDERA
                     RFVETNRLLDYCFNSYALEKLVAQNQVLPERLIVKQAAKQRLRVKASQTLTVVRPKDQ
                     TELSYSLRIKDKALKAPIRQNKKVGTLIYQDPKLIDSGYLAAPPAVAIVSAKSIPEKG
                     KLSKLFDFFQKVIG"
     gene            complement(1539..2777)
                     /locus_tag="TV191_001487"
     CDS             complement(1539..2777)
                     /locus_tag="TV191_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEL1507987.1"
                     /translation="MKKVLIALTILAISCLAYPAQADHYDISAKHAIAVELDSGKILY
                     EKDADKTVSVASLSKVLTAYLVYKEVQAGKLKWDSSVTISNYPYKLTTNYTISNVPLD
                     ARKYTVKELLKALIVTNANSPAIALAEKIGGTEAKFVDKMIAQLKDWGITGAKVVNAS
                     GLPNHILGEHIYPGSSLDDDNQFSAADLALVTSHLLKEFPEVLKLSSQVQAEFNHQQI
                     FSYNYMLKGMPNYRDGVDGLFVSYSEKGGSSFLATSVENNMRIITVVLNADHAQDNDT
                     AVFTATNQLLQYVLTHFKKVVVLEKGKPDQLKALPVLDSPQKKIQLVPKKKLTMIKAL
                     DDKSKTTFQVSDTKNPLVAPIQKGQTLAKATLNDHSLIGKGYLGQAPSVELVAQKKVP
                     KSFFLKVWWNHFVRYVNQYL"
     gene            3085..5061
                     /locus_tag="TV191_001488"
     CDS             3085..5061
                     /locus_tag="TV191_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003102586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1507988.1"
                     /translation="MKKSKWLATLGVAALSVSILAACGNSSSKSSESKIYSYVYSSDP
                     STLDYISTSKATTNDITTNAVDGLLENDQYGNLIPSLAKDWKVSKDGLTYTYTLRDGI
                     KWYTSDGEEYADVTAEDFVAGVKHAADVNSDALYIIQDSIKGLSDYLNGKTKDFSTVG
                     VKALDKKTVQYTLNQPESFWNSKLTYSVLAPVNADFLKSKGKDFGKATDPSSILYNGP
                     FLITALTSKSSIELVKNENYWDAKNVHLDGVQLTFYDGQDQESLFRNFDDGAYSAARL
                     FPTTPSYKTVKKKYGDSITYGQQNATLYYAAFNLNRTSYNHTKKTSDSQKSDTQKAIL
                     NKDFRQAMTFAFDRIAYQAQSAGEDAANKSLRSTLVPPTFVKIGDKNFGDVVEEHLVT
                     YGSQWENVNLDDAQDGLYNPEKAKASFEKAKAALQAEGVQFPIHLDYPMDQTATVLLQ
                     QARSMKQSIEKTLGTDNVVIDIIELQKDVYENISYLAETPAQNDWDISTASGWGPDYV
                     DPSSYLDIFNPTLANSQTKSIGLEPGKDLAIASAAGLDEFTKLVTEAGKITDDLNARY
                     TLYAKAQAALTDSAIYIPTISLGGTPRVTKVVPFSGAFAWAGTKNDFYYKYVKLQDKP
                     VTAKQYDKALAEWKKEKKKSNEKYNNSLEKHIEK"
     gene            5125..6624
                     /locus_tag="TV191_001489"
     CDS             5125..6624
                     /locus_tag="TV191_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004184189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1507989.1"
                     /translation="MKKYIFERILRSLVSILLVTALTYTIVFTLVPKSLIFKQDPNYN
                     KMVTTPDKKTNYLNTVFENMGYISYYSSKELQNKASKLDPSVTTAPTKANEKIYQKYI
                     ASVGNGWKLGRFTESKGFYAVREIPIYERVWNFFSHLVVIDHPWKIKDPKNPNLERYV
                     RPEIDPAVGPALVGSGTKHKYLIYFNKQFPFIHQNIVTFDLGVSYPTYANIPVVQVIT
                     QGQGRTLQKEVTFPTGKTKLSSIDIYSRTYKTPSSLDSKDIANFGKGDAYTNTQNNYA
                     EPSMIANSFKIGIVGVLLSYLFGLPIGMLMAYYKNGWFDRFSTAATTFMLALPSIALI
                     YIVRFVGSYLGLPDTFPLLGAGDVRSYVLPALILGILGTPSTVVWFRRYIVDLQGSDF
                     VRFARAKGLSEFEISKNHLFKQAMVPIVNGIPQAIVGTIAGATLTETVFAFPGMGKML
                     IDSIKAANNSMVVGLVFIFAVLSILALLVGDILMTILDPRIKLSGKGGK"
     gene            6624..7550
                     /locus_tag="TV191_001490"
     CDS             6624..7550
                     /locus_tag="TV191_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1507990.1"
                     /translation="MAAIDKNKFTFVELDSYASEVIDAPAYSYWKSVFRQFFSRKSTI
                     LMLVILIAIILMSFIYPMFANYDFGNVSNINDFSKRYIAPNAEYWFGTDQNGQSLFDG
                     VWYGARNSILISVIATIINMIIGVIVGGIWGVSKAVDKVMIEVYNIISNLPQMLIIIV
                     LTYSIGAGFWNLIFAFCVTGWIGIAYSIRVQILRYRDLEYNLASQTLGTPTHKIVIKN
                     LLPQLVSVIVSMVSLLLPSYISSEAFLSFFGLGLPITEPSLGRLISNYSNNLTTNAYL
                     FWIPLTTLILVSLPLYIVGQNLADASDPRTHR"
     gene            7559..8629
                     /locus_tag="TV191_001491"
     CDS             7559..8629
                     /locus_tag="TV191_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1507991.1"
                     /translation="MTEKQEIILSAKNIVVEFDVRDRVLTAIRDVSLDLYKGEVLAVV
                     GESGSGKSVLTKTFTGMLEANGRVASGTITYAGQELTELKNHKDWEAIRGSKIATIFQ
                     DPMTSLDPIQTIGSQITEVIVKHQKKSRSEAKALAIDYMTRVGIPEPEKRFGEYPFQY
                     SGGMRQRIVIAIALACKPDILICDEPTTALDVTIQAQIIDLLKTLQKEYHFTIIFITH
                     DLGVVASIADKVAVMYAGEIIEYGKVEEIFYDPRHPYTWSLLSSLPQLADEKGVLFSI
                     PGAPPSLYKPIVGDAFAPRSQYAMAIDFEETVPRFTISDTHWAKTWLLHPDAPKVQKP
                     AVIQDLHQKILKKMSRQEEGNV"
     gene            8622..9545
                     /locus_tag="TV191_001492"
     CDS             8622..9545
                     /locus_tag="TV191_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1507992.1"
                     /translation="MSEKLVEVKDLEISFGEGKKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNETSSGEIRYDGKIINGKKSKSEANELIRKIQMIFQDPAASLNE
                     RATVDYIISEGLYNFNLFKTEDERKEKIKQMMSEVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMDPEFVIADEPISALDVSVRAQVLNLLKKIQSEKGLTYLFIAHDLSVVRFIS
                     DRIAVIHKGVIVEVAETEELFVNPVHPYTKSLLSAVPIPDPILERQKKLVVYHPEQHD
                     YSVDKPSMVEIKPNHFVWANQVEAERYRKEL"
BASE COUNT         2867 a         1899 c         2010 g         2905 t
ORIGIN      
        1 ccaatgactt tttgaaaaaa gtcaaataat ttgctaagtt tccctttttc aggaatgctt
       61 ttagctgaga caatagcaac agctggcggt gctgctagat agccactgtc aatgagctta
      121 ggatcctgat agataagggt accgaccttt ttattttgac gaattggggc cttgagtgct
      181 ttgtctttga ttcgtagcga gtaagacagc tctgtctggt ccttaggccg aacaaccgtt
      241 aaggtttgac tagccttgac ccttagcctt tgctttgctg cttgtttaac aatcagtctt
      301 tcaggcaaaa cttggttttg agcaacaagc ttttccaagg catagctatt aaagcaataa
      361 tcaagcaggc gattggtctc aacaaagcga gctcgctcat cagtgtcaga ttgatcagca
      421 tggagaatga cagaaataac tcgcatatta tcctgcacag ctgttgcaat cattgtttgt
      481 ccggcttggc tggtagtgcc tgttttaagg ccatcaaccc cagctctgcc catctcgcga
      541 ccggctaata gtagattaga actaggcaag gccttttcac cccatttcaa ttggggctgt
      601 gaggagatgg tgagaagctc aggaaagtct tgaatcaact gctgtgcaat cagtgccaga
      661 tctctagctg tcatctgatt ttcatcatct ggctgtgagc ctggatatag atgccccttt
      721 agcatactgt tgtttagccc tgaagcattg acaagaagat agtctctaat cccccaagcc
      781 tccagctgtt ttttcatcat gtctacaaat gtaggctctg agccagcgat atgctctgct
      841 agagctacag cagagctatt agcactaata atcaggctag attcaacaag ctctttgata
      901 gtgtaaggtc tttgctcaaa tgctgggttg ctgatatcag gatcagtggc taattgcaga
      961 gcatattcag atagggttac ctgactatcc cactggagcc gtcctgcctt aatttccttc
     1021 aggactaggt agacggttag tagctttgtt agagaagcaa tgggcgcctt ttgctgggcc
     1081 tctttggcat ataggatttt tccagttgtc atttcaaccg caatggcttg acgactatta
     1141 acagagaagt tctcagcaaa ggaagtattt gtgatcagac acatgagcgc agcaagtgtc
     1201 acaataagtt ttttcatacc atcattgtag caaggaaata gtgatcggtc aaaaggtcat
     1261 tgagtacctt taaagaaggc taagtcaaga ctctgagtga gatgacgtcc ccaaaaatca
     1321 agcctcaaaa aaaccgtctg acatcaacag actaaagctg tcaattcata cggttttgct
     1381 gtttgcagag cttttgtagg ccttagagct tgctaggagc tcttttagct accttcttgg
     1441 agagcttgac acaatggtca atttttgcga gataagccta atgaagccct gagtgaggcc
     1501 ttggcactaa tgaggacata aggcataaaa gctagtcatt agagatattg gttaacataa
     1561 cgaacaaaat gattccacca gacctttaaa aagaagcttt ttggcacctt tttttgagcc
     1621 accagctcaa cgcttggcgc ttgacctaga tagccttttc cgattaagct atgatcatta
     1681 agtgtggcct ttgcgagtgt ttgtcctttt tggataggcg ctactaaggg atttttggta
     1741 tcgcttactt gaaaagtcgt tttggacttg tcgtcaagcg cttttatcat agtgagcttc
     1801 ttttttggca ctagctggat cttcttttga ggactatcta aaacaggaag cgctttaagc
     1861 tgatctggtt tacccttttc aaggacaaca acctttttaa aatgcgtcaa aacatactgc
     1921 agcaattggt ttgtcgctgt aaagacggcc gtatcgttgt cctgggcatg gtcagcattg
     1981 aggacaactg taataatacg catattgttt tcgacactag tggctaaaaa agaagagcct
     2041 cccttttcag aatagctaac aaaaagccca tcaacaccat cacgatagtt aggcattccc
     2101 tttagcatat agttgtatga aaaaatctgt tgatgattaa actcagcttg aacctgactt
     2161 gatagcttta aaacctcagg aaattccttt aaaagatggc tagtgacaag agcaagatcg
     2221 gctgcactaa attgattatc atcatcaaga ctagatcccg gatagatatg ctctcctagt
     2281 atgtggttag gcaggccact agcattgacg accttggcac ctgtaatgcc ccagtctttc
     2341 aattgagcga tcattttatc aacaaactta gcctctgttc ccccgatttt ttctgccagg
     2401 gcaatagcag ggctattagc attggtgaca ataagagcct ttaacagctc tttaacagta
     2461 tattttctag catctaaggg cacattgctt atggtgtagt tggtggttag tttgtaaggg
     2521 tagttagaga tcgttacgga gctatcccat tttaactttc ctgcttgcac ctctttgtac
     2581 accaaataag ctgttaaaac cttgcttaga gaagccacag aaacagtctt gtcggcgtcc
     2641 ttttcgtata gaatcttacc gctatcaagc tcaacagcaa tcgcatgctt ggcgctaata
     2701 tcataatgat cagcctgtgc tggataggcc agacaagata tggctaatat ggtcaaagct
     2761 attaaaacct ttttcatttg aataatcctt ctagtcgttt ttttaattat accataattt
     2821 ttcaagaagc ttgactaaac ctctcagaga agagagatca ttatgagaaa atgctagctg
     2881 ttatgatagc gataacgaac tgtataaaaa tagcaaataa tgtatcttaa acgtcatcag
     2941 atcgtcaaca gaaaaaatct tgcaaaatat tcagataatt ttgcgatcgc tatttccatc
     3001 agctaaaatt tgtggtataa tagctccaat taaccaattt catttatgct gataaatgaa
     3061 aaataacgtt taggggtgac ttctatgaag aaaagtaaat ggttggcaac gctgggtgtc
     3121 gcagcgctgt cggtgtccat cctggcagcc tgtggaaaca gctcaagtaa aagcagtgaa
     3181 tcaaagattt atagctatgt ctattctagt gatccaagta ctttagacta tatcagtaca
     3241 agtaaagcaa caacaaatga cataacaaca aatgctgttg atgggctttt ggaaaatgac
     3301 caatatggga atttaatccc ctctcttgct aaggattgga aggtctcaaa ggacggcttg
     3361 acctatacct acacgcttcg tgatgggatt aagtggtaca catctgatgg agaagagtat
     3421 gcagatgtga cagctgagga ttttgtagct ggagtaaagc acgcagcaga tgttaactct
     3481 gatgccctat atatcattca ggactctatt aaaggcttaa gcgattactt gaacggtaag
     3541 accaaggact tttcaaccgt aggtgtcaaa gcgcttgaca aaaaaacagt tcagtacacc
     3601 cttaatcaac cagaaagctt ctggaattca aagctaacct atagtgtcct agctccggta
     3661 aatgctgact tcttaaaatc aaagggcaag gattttggta aggcaacaga tccatcatct
     3721 atcctgtata atggtccatt tcttatcaca gctttgacaa gcaaatcctc tatcgagctt
     3781 gtcaaaaacg aaaattattg ggacgctaag aatgttcacc ttgatggtgt tcaattgacc
     3841 ttttacgatg gacaggatca ggagtcattg tttagaaact ttgatgacgg tgcttactca
     3901 gcagcgagat tattcccaac aacaccttct tataaaactg ttaagaaaaa atatggagac
     3961 agtatcactt acggacaaca aaatgctact ctctactatg cggcgtttaa cctaaatcgt
     4021 acgtcttaca accacactaa gaagacctca gatagccaaa aatcagatac ccaaaaggct
     4081 atcttaaaca aggatttccg tcaggctatg acatttgcct ttgatagaat tgcttatcag
     4141 gcgcaatcag caggtgaaga tgcagctaac aaatcgcttc gtagcacact tgtgccaccg
     4201 acatttgtga aaattggcga caaaaacttt ggtgatgttg ttgaggagca cttggtgacc
     4261 tatggtagcc agtgggaaaa tgtaaatcta gatgatgcac aggatggctt gtacaatcct
     4321 gaaaaggcaa aagcatcatt tgaaaaagca aaagcagccc tacaagctga gggtgtacag
     4381 ttcccaatcc atcttgatta cccaatggat caaactgcaa cggtgctctt acagcaggct
     4441 cgctctatga agcagtcaat tgagaaaaca ttaggaactg acaatgttgt gattgatatt
     4501 attgagcttc agaaagatgt ttatgaaaat attagttatc tcgccgaaac tcctgctcaa
     4561 aatgactggg atatttcaac ggcttctggc tggggacctg attatgtcga cccatcgtca
     4621 tatcttgata ttttcaaccc aacgcttgca aactcacaaa caaaatcaat tggacttgag
     4681 ccaggtaagg atttggccat tgctagtgca gctggcttag acgaatttac aaagctagtg
     4741 acagaggcag gcaagattac tgatgatctc aacgcccgct acacgctcta tgctaaggct
     4801 caagcggcat tgacagactc tgctatttac atcccgacta tttcacttgg tggaacacca
     4861 cgtgtaacta aagtggtacc gttttcaggc gcctttgctt gggctggtac taaaaatgac
     4921 ttttattaca aatacgtcaa gctacaagat aagcctgtaa ctgctaaaca atatgacaaa
     4981 gcattagccg agtggaaaaa agaaaagaaa aaatctaacg aaaaatataa taattccctc
     5041 gagaagcata ttgaaaaata aattgatgtt cattaagaac tttctcttag aggaggaagt
     5101 tcttttgaac tgctggggac tagaatgaaa aaatacatat ttgaacgcat attgaggtcg
     5161 cttgtttcaa tcctgctggt aaccgcacta acctatacta ttgtctttac cttagtgcca
     5221 aaaagcttga tttttaagca agaccctaat tacaataaaa tggtgacaac acctgataag
     5281 aaaaccaatt atctaaatac tgtttttgaa aatatgggct atatttccta ttacagcagt
     5341 aaagaactgc agaataaggc ttcaaagctt gatccttctg taacaactgc accaaccaag
     5401 gccaatgaaa aaatatatca aaaatatatt gcttctgtcg gtaatggttg gaagcttggg
     5461 cgctttacag aaagtaaggg attttatgcc gttagagaga ttccaatcta tgagcgcgtg
     5521 tggaatttct ttagccattt ggttgtgatt gatcacccat ggaaaatcaa ggatccaaaa
     5581 aatccaaatc tagagcgtta tgtgcgacca gaaattgacc ctgctgttgg tccagcctta
     5641 gttggctctg gtactaagca caaatacttg atttacttca acaagcaatt tccatttatc
     5701 catcaaaata tcgtaacctt tgatttggga gtgtcctatc caacctatgc caatattcca
     5761 gttgttcagg ttatcactca aggacaagga agaacacttc aaaaagaggt caccttccca
     5821 acaggcaaaa caaagctgtc ttcaatcgat atttactctc gaacctataa aacaccaagc
     5881 tctttagata gcaaggatat tgccaatttt ggtaagggtg atgcttatac caatacacaa
     5941 aataactatg cagagccatc tatgattgca aattccttta agattggtat tgtcggtgtc
     6001 ttgttgtcct atctttttgg tttgccaatt ggtatgctga tggcttatta taagaatggc
     6061 tggtttgacc gcttttcaac ggctgccaca acctttatgt tagccctgcc aagcattgcg
     6121 cttatctata ttgttcgatt tgtcggttct tatttgggct tgccagatac ctttccgctg
     6181 ctaggagcag gagatgttag gtcttatgtg ctgcctgctc ttatattagg aattcttggt
     6241 acaccaagta cagtagtttg gttccgacgc tatattgtgg acttgcaagg cagtgatttt
     6301 gttcgctttg cacgagcaaa ggggctttca gaatttgaga tttcaaaaaa tcatctcttt
     6361 aagcaggcta tggtgcctat tgttaacggt attccacaag ccattgtcgg aacaattgcc
     6421 ggtgcaacct tgacagaaac cgtctttgct ttcccaggaa tgggtaaaat gctgattgat
     6481 tccataaaag ctgctaataa ctctatggtt gttggtcttg tctttatttt tgctgtttta
     6541 tcaatattag ccttgctagt aggtgatatt cttatgacaa ttttagatcc acgtattaaa
     6601 ttatcaggta aaggaggtaa gtaatggcag caattgacaa aaataaattc acctttgttg
     6661 aattagatag ctatgcatca gaagtcattg atgcccctgc ttactcttat tggaaatctg
     6721 tatttagaca atttttctca cgtaaatcaa ctattttgat gctggttatt ttgattgcta
     6781 ttattttgat gagcttcatc taccctatgt ttgccaacta tgactttggt aacgtgagca
     6841 atattaatga tttttcaaaa cgttatatag cacctaatgc agagtattgg tttggtacgg
     6901 atcaaaatgg tcaatcgctc tttgatggcg tttggtatgg tgctagaaat tcaatcttaa
     6961 tttcagttat tgcaaccatc atcaatatga ttatcggagt cattgtcggt ggtatttggg
     7021 gtgtttccaa agcagttgat aaggtaatga ttgaggtgta taatatcatc tctaacctgc
     7081 cgcaaatgct cattatcatt gtgttgactt attctatcgg agcaggcttt tggaacttga
     7141 tttttgcttt ttgtgtgaca ggctggattg ggattgctta ttcgattcgt gtacaaattt
     7201 tgcgttatcg tgatttagaa tacaatttag caagtcagac cttaggaaca cccacccata
     7261 aaattgtcat taaaaatctt ttacctcaat tggtttcggt gatcgtttcg atggtttcct
     7321 tgctattgcc gtcctatatt tcatcagagg ccttcttatc cttctttggc ttgggattac
     7381 caatcacaga accaagcttg ggtcgattga tttcaaatta ttcaaacaat ttaacaacaa
     7441 atgcctattt attctggatt ccattgacaa ctcttattct tgtttcccta cctttataca
     7501 ttgtaggaca aaacttagca gatgctagtg atccaaggac gcatagatag gagaagtcat
     7561 gactgaaaaa caagaaatta tattaagtgc taaaaatatt gttgtagagt ttgatgtgcg
     7621 tgatcgtgta ctgaccgcta ttcgtgatgt ttctcttgat ttgtataagg gagaggtatt
     7681 ggctgttgtt ggtgagtcag gctctggcaa gtctgtttta actaagacat ttacaggaat
     7741 gctggaggca aatggacgtg ttgcttcagg gacgataacc tatgcaggtc aagaactaac
     7801 agagcttaaa aatcataagg actgggaagc tattcgcggc tctaaaattg ccactatctt
     7861 tcaggaccca atgactagtc tagatccgat tcaaacgatt ggcagccaga ttactgaggt
     7921 tattgttaag catcagaaaa aatctagatc agaggctaag gctttagcaa tcgactatat
     7981 gacaagggtc ggtattcctg agccagaaaa gcgttttgga gagtatcctt tccaatattc
     8041 tggcggtatg agacagcgta ttgttattgc cattgcccta gcttgtaagc cagatattct
     8101 gatctgtgat gagccgacaa cagctcttga cgttaccatc caggctcaga ttattgacct
     8161 attaaagacg cttcaaaaag agtatcactt caccattatc tttatcacgc atgacctagg
     8221 agtggttgca agtattgctg ataaggttgc tgttatgtac gcaggggaga ttattgaata
     8281 cggaaaggtt gaggaaatct tctatgatcc tcgtcacccc tacacatgga gcttattatc
     8341 tagcctaccg caattggcag atgaaaaggg cgttctgttt tcaattccag gggcacctcc
     8401 gtccctatac aagccaattg ttggtgatgc ctttgcgcca cgctctcagt atgctatggc
     8461 cattgatttt gaagaaacag ttcctcgttt tacgatcagt gacacgcact gggcaaaaac
     8521 ctggctccta cacccagatg ctcctaaggt tcaaaaacca gctgttattc aggatttaca
     8581 ccaaaaaata ttgaaaaaaa tgtcacgcca ggaggaagga aatgtctgaa aaattagttg
     8641 aagtaaaaga cctggagatt tcctttggag agggaaagaa aaagtttgtt gccgttaaaa
     8701 atgccaattt ctttatcaat aaaggagaaa ccttttctct tgttggagaa tcaggcagtg
     8761 gaaagacaac aatcggtcgt gccatcattg gtttaaatga gacaagttca ggcgaaatcc
     8821 gctatgatgg taagattatt aatggtaaaa aatcaaaatc tgaagctaat gaactgatta
     8881 gaaaaatcca aatgattttt caggatccag cagccagcct gaatgagcgt gcaacggttg
     8941 attatatcat ctcagaaggc ctttataatt ttaacctatt caagacagaa gatgaacgta
     9001 aagaaaaaat taaacagatg atgtcagagg tgggcttgct tgcagagcac ctgacacgct
     9061 accctcatga gttttcaggt gggcagcgtc agcgtatagg cattgcaaga gcgcttgtaa
     9121 tggatccgga gtttgttatt gctgatgagc cgatttcagc tcttgatgta tctgttcgtg
     9181 cccaagtctt gaatctgttg aagaaaatac agtctgaaaa aggcttgacc tatttattca
     9241 ttgctcatga tttatcggtt gtgcgtttta tttcagatcg tattgctgtt attcacaaag
     9301 gagtaattgt tgaagtcgcc gaaacagaag agctttttgt taaccctgtt cacccttata
     9361 ccaaatctct gctgtcagca gtaccaattc cagatcccat tttagagcgt caaaagaaat
     9421 tggtggttta tcatccagag cagcatgact attctgttga caagccatca atggtggaaa
     9481 tcaaaccaaa tcacttcgtc tgggctaacc aggtggaagc ggagcgttac cgcaaagagc
     9541 tttaagatta gttatcatca cataacagaa tttagcctca gctagattct gtttttgcct
     9601 tccttgggta gtcttttttg ttctgacaag gatagaaata tccagcattt tccatctatt
     9661 tacaaaaaac ctgtcaaaac c
//
LOCUS       DARYXW010000073         9359 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.073, whole genome shotgun sequence.
ACCESSION   DARYXW010000073 DARYXW010000000
VERSION     DARYXW010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9359
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.073"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            <1..484
                     /gene="glmU"
                     /locus_tag="TV191_001493"
     CDS             <1..484
                     /gene="glmU"
                     /locus_tag="TV191_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016740.1"
                     /note="forms a homotrimer; catalyzes the acetylation of
                     glucosamine-1-phosphate and uridylation of
                     N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc;
                     function in cell wall synthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEL1507993.1"
                     /translation="SRLGEGVVVSQSVIEDSVLADGVTVGPYAHIRPDSQLDESVHIG
                     NFVEVKGSHLGANTKAGHLTYLGNAEIGSEVNIGAGSITVNYDGQRKYQTVIGDHAFI
                     GSHSTLIAPVEVGENALTAAGSTIAQSVPADSVAIGRSRQVVKEGYAKRLPHHPNQAK
                     "
     gene            515..1069
                     /locus_tag="TV191_001494"
     CDS             515..1069
                     /locus_tag="TV191_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL1507994.1"
                     /translation="MDFEEKTIKRQEIFDGHIFKVAVDDVQLPNGLGQAKRELIFHRG
                     AVAILAVTPERKLLIVKQYRKAIEAISYEIPAGKLEVGEANSALEAAARELEEETAYS
                     GDLRLIHEFYTAIGFCNEKIKLYLATDLQRVANPRPQDADEVIELLELSYQECMDLVA
                     QGKLVDAKTIIALQYYALHFGGDV"
     gene            1069..1317
                     /locus_tag="TV191_001495"
     CDS             1069..1317
                     /locus_tag="TV191_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1507995.1"
                     /translation="MGKPLLTDDIIEKAQRGEQFEPDDYADFETKIMTFEDKHTDRIY
                     KSRRIENAKRSRFQSRLNLILLAVLVLIALLVYAVFNL"
     gene            1341..2042
                     /locus_tag="TV191_001496"
     CDS             1341..2042
                     /locus_tag="TV191_001496"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEL1507996.1"
                     /translation="MKIGIIAAMEEELRFLLEQLHDSQEHQVLSNTYYTGRLGRHELV
                     LVQSGVGKVMSAMTVAMLAEHFQADAIINTGSAGAIASGLAIGDVVVADRLVYHDVDV
                     TAFGYDYGQMAAQPLYFDSDSKLVETFKQVLDQEKTNSRIGLIATGDSFIAGQDSIDT
                     IKAHFPETLAVEMEGAAVAQAAQAAGKPFIVVRAMSDTAAHDANMTFDQFIVEAGKKS
                     AKVLIAFLEALPDKK"
     gene            complement(2098..2745)
                     /locus_tag="TV191_001497"
     CDS             complement(2098..2745)
                     /locus_tag="TV191_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEL1507997.1"
                     /translation="MTPNKEDYLKCIYEIGEQNIKISNKMVAERMKVSAPAVSEMIKK
                     MIAQGWIVKDKTCGYYLTEQGQRLVANLYRKHRLMEVFLIHQLGYTAREVHQEAEVLE
                     HTVSDMFIDRLDKTLGYPTFCPHGGTIPRRQQPLIEINKTTLNTIKELGIFRLSRVHD
                     HFELIQYLEAHQLTINSEFRLIQIDDFAKTYTITYADKELIIPENIAKQLFVTAI"
     gene            2891..3823
                     /locus_tag="TV191_001498"
     CDS             2891..3823
                     /locus_tag="TV191_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HEL1507998.1"
                     /translation="MKKKLSLALSAFLAVFMLVACSNGGNKEAKSDKLKVVVTNSIIA
                     DMTKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVEKTSNADLILYNGINLEDGGQAWFT
                     KLVKNAKKEKDKDYFAVSDGIDVIYLEGESEKGKEDPHAWLNLENGVIYSKNIAKQLI
                     AKDPKNKETYENNLKAYVEKLEKLDKEAKSKFDAIADNKKLIVTSEGCFKYFSKAYGV
                     PSAYIWEINTEEEGTPDQISSLIEKLKDVKPSALFVESSVDRRPMETVSKDSGIPIYA
                     EIFTDSVAKKGQDGDSYYAMMKWNLDKISEGLAK"
     gene            3883..4608
                     /locus_tag="TV191_001499"
     CDS             3883..4608
                     /locus_tag="TV191_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEL1507999.1"
                     /translation="MIDTQNLSVSYNGNVKALDNISLQIKGPAIVGIIGPNGAGKSTL
                     MKAMLNLLDYSGQVTVDQKDGRRLGHTIAYVEQRSMIDYNFPITVKECVSLGTYTRLG
                     LFRRVGKKEYDQVDQLLEQVGLAGFGNRPIKSLSGGQFQRMLVARCLIQESDYIFLDE
                     PFVGIDSVSEKIIIDLLKDLKKAGKTILIVHHDLSKVEHYFDELVVLNKELIAYGSVD
                     EVFTVETLSKAYGDHLFLGKGMF"
     gene            4609..5442
                     /locus_tag="TV191_001500"
     CDS             4609..5442
                     /locus_tag="TV191_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEL1508000.1"
                     /translation="MYLKFFEGLMSYHFLQNALITAVVIGIVSGAVGCFIILRSMSLM
                     GDAISHAVLPGVALSFILGINFFVGAIVFGLLASVIITYIKENSVIKGDTAIGITFSS
                     FLALGVILIGIANSSTDLFHILFGNILAVQDSDKWITIIVSVFVLAIIVLFFKELLIT
                     SFDPVLARSMGMKVTAYHYLLMILLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKVMLVISSCLGAMTSVLGLYLGYTFNIAAGSSIVLTSAVVFLISFFVSPKQGYFKKH
                     S"
     gene            complement(5598..6404)
                     /locus_tag="TV191_001501"
     CDS             complement(5598..6404)
                     /locus_tag="TV191_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEL1508001.1"
                     /translation="MKKLLSFGLIGLALLSLSGCESIDRAIKGDEYVDEKIAREESET
                     AAKAYEAKIKKALKADADQFPQLNKEVDKDEAKVIIKTNQGDITLKLFPKYAPLAVEN
                     FLTHAKEGYYDKLLFHRVINNFMIQTGDPKGDGSGGESIWKGKDSKKDAGQGFANEIS
                     PFLYNIRGALAMANAGADTNGSQFFINQSKLNQAKALSIDNYSKPIIDSYEEGGNPSL
                     DGGYTVFGQVIEGMDIVDKIAASPVGPNDKPIENITINAIDIVKDYSFKK"
     gene            complement(6491..6664)
                     /locus_tag="TV191_001502"
     CDS             complement(6491..6664)
                     /locus_tag="TV191_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508002.1"
                     /translation="MEKEFNTLTYGKLPLQIDMGHGKLIPKGVEVKAIVDMQTGQVTF
                     KVSQEDLEKLRNS"
     gene            6784..9183
                     /locus_tag="TV191_001503"
     CDS             6784..9183
                     /locus_tag="TV191_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEL1508003.1"
                     /translation="MARRTQRQKNPPKRRLTKAELEKQKAIKRMIASFSCALLLVFAM
                     LRLGALGVTLYNLIRFMVGDLANLLMLAVLFYLFFFKWLRQKDGLIAGFIILFLGLLV
                     EWHAYLFSLPQLAHQAIVAGTIQLITNDLLAFKVSEFVGGGMLGAMLYKPISFLFSNI
                     GSYFIGFLFILLGLFLMTPWDIYDVSHFVKTLFEKLSLAYQENKEKRFVEREKQRLLA
                     EEERLAREALEEQEYLANQAINPETGELLAEPEDLLMEMADQKESEAFFEPEILAYDS
                     HPADDEPEAFGDEEESVPEAPLTGASAIAGEAPLSDDEELSVEVDFTPKTNLLYKLPT
                     IELFAADKPKNQFKEKYLVRQNIKVLEDTFRSFGIDVKVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLADDLALALAAKDVRIEAPIPGKSLVGIEVPNSEVATVSFRELWEQSNTS
                     DDKLLEIPLGKAVNGSARSFDLTRMPHLLVAGSTGSGKSVAVNGIISSILMKARPDQV
                     KFLMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFSKVGVRNI
                     AGYNAKVEAYNKQSEQKQIPLPMIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRIAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVSFIKEQAEADYDDYFDPGEVSDSDYGSSGAPEGDP
                     LFEEAKALVLETQKASASMLQRRLSVGFNRATRLMDELEEAGVIGPAEGTKPRKVLQT
                     N"
BASE COUNT         2577 a         1787 c         2200 g         2795 t
ORIGIN      
        1 ttcgaggctt ggtgagggcg tagtggtgag ccagtcagtg attgaggatt cagtcctagc
       61 agatggtgtg acagtagggc cctatgcgca cattcgccca gactcccagc tcgatgagag
      121 cgttcatatt gggaactttg tagaggttaa ggggtctcat ctaggggcca ataccaaggc
      181 agggcatttg acttacctgg ggaatgccga gattggctca gaggttaata ttggtgcagg
      241 aagcattacg gttaattatg atggtcaacg gaaataccag acagtgattg gcgatcacgc
      301 ttttattggg agtcattcga ctttgatagc tccagtagag gttggggaga atgctttaac
      361 agccgcaggg tctacgatag cccagtcagt gccggcagac agtgtggcta tagggcgcag
      421 ccgtcaggtg gtgaaggagg gctatgccaa gaggctgcca catcacccaa atcaagcaaa
      481 gtaaaatgat ggagagaaag caaggagatc agacatggat tttgaagaaa aaacgattaa
      541 aaggcaagag atttttgatg gtcacatttt caaagttgcg gtagatgatg tccaattgcc
      601 aaacggccta ggtcaggcta agcgcgaatt gatttttcat cgcggtgcag tcgctatatt
      661 ggctgtaacg ccagagcgta agctgttaat tgtcaagcag taccgtaagg ctatcgaagc
      721 gatttcttat gaaattcctg ctggaaaact agaggtcggt gaggccaact cagcattaga
      781 agcagcagca cgagagctgg aggaagaaac cgcctattct ggtgatttgc gtcttattca
      841 cgagttttat acagcgattg gtttttgtaa tgaaaaaatt aagctgtact tggcgacaga
      901 cctgcagaga gttgccaatc ctagaccaca ggacgcagat gaggtgattg agcttcttga
      961 gctgagctat caagaatgta tggatctagt ggcacaagga aagcttgtcg atgctaaaac
     1021 catcattgcc ctgcaatatt acgcccttca ttttggaggt gatgtgtaat gggcaagccc
     1081 ttgctgactg atgacattat cgaaaaggct cagcgcggag aacagtttga gcctgacgat
     1141 tatgcagatt ttgaaaccaa aatcatgacc tttgaggata agcatactga tcgtatttac
     1201 aaaagtcgca gaattgaaaa tgcaaagcgc agtcgctttc aatcgcggtt aaatctgatt
     1261 ctcttagcgg tgcttgtctt gattgctctc ttggtttatg cggtctttaa tttatagaaa
     1321 aaaacaaata aggatatcat atgaaaattg gaattattgc ggctatggaa gaggagctgc
     1381 ggtttttatt ggagcagctc cacgatagtc aagagcatca ggtgctttcc aatacctact
     1441 atacaggtcg tcttggtcgc catgagctcg tcttagtcca atctggtgtt ggaaaggtca
     1501 tgtcagcgat gacagttgcg atgctagcag agcattttca ggctgacgct attataaata
     1561 caggatcggc tggagcaata gctagtggct tggctattgg tgatgttgtt gttgctgatc
     1621 gcttggtgta tcatgatgtg gacgtgacgg cctttggcta tgactatggt caaatggctg
     1681 cgcagcccct ttactttgac agtgatagca agctggttga gacctttaag caggtgcttg
     1741 atcaggaaaa gaccaatagt cggattggcc tgattgcaac aggagatagc tttattgccg
     1801 gccaagacag tattgatacc atcaaagcac atttcccaga gaccttagca gtggaaatgg
     1861 agggagcagc agtggcacag gcagctcaag ctgctggcaa gccatttatt gttgttaggg
     1921 cgatgagtga cacagcggcc cacgatgcta atatgacctt cgatcagttt attgttgagg
     1981 ctggaaaaaa atcagccaag gtcttgatag cctttttaga ggccttacct gataaaaaat
     2041 gatgaccaaa aaaacctgat agcctgtggt gacagcaaat atcaggtctt tttttattta
     2101 aatagcagta acaaagagct gcttggcgat gttttcagga atgatcaatt ccttatctgc
     2161 ataagtgatg gtataggttt ttgcgaagtc atctatttga atcagtctaa actcactatt
     2221 gatcgtcagc tggtgtgctt ctaggtactg gataagctca aagtgatcat gcaccctgct
     2281 caaacgaaaa attcccagct ctttaatagt attaagcgtt gttttgttga tttcgattag
     2341 tggctgctgg cggcgtggaa ttgtccctcc atgagggcaa aaagtaggat agccaagggt
     2401 tttatccaag cgatcaataa acatatctga cacagtatgc tctagtacct cagcctcttg
     2461 gtgcacctct ctagcagtat agcccagttg atggatcaag aaaacctcca tcaatcggtg
     2521 cttacgataa agatttgcca ctaagcgctg cccttgctct gttagataat agccgcaggt
     2581 cttatccttt acaatccagc cttgtgcgat cattttctta atcatttctg acacagcggg
     2641 tgcagaaacc ttcattctct ctgcaaccat tttgttagaa attttaatgt tttgctctcc
     2701 gatttcataa atacatttca aatagtcttc tttattaggc gtcatgtcta aaagcctttc
     2761 tcttatttat aatgattatt atatcagatt atttcataaa aatcttgaca aaggcctaaa
     2821 aaaaagttat gctaatagca taattaacta tacttaatta attaaataat agatcctaag
     2881 gagataactg atgaaaaaga aacttagcct cgccttgagt gcttttttgg ctgttttcat
     2941 gctggttgcc tgctctaatg gtggaaacaa ggaagctaag agtgacaagc tcaaggttgt
     3001 ggttaccaat tccattattg ctgacatgac taaaaatatt gcaggtgaca agattgactt
     3061 gcacagcatt gtgccgattg gtcaagatcc gcatgagtat gagccattgc cagaagacgt
     3121 tgagaagacc agcaatgccg atcttattct ctataacggt attaaccttg aagacggcgg
     3181 acaggcttgg tttacaaagc ttgtaaaaaa tgctaagaag gaaaaggaca aggactactt
     3241 cgctgtatct gatggtattg atgtgattta cctagaaggt gaaagtgaaa aaggcaagga
     3301 agaccctcat gcttggttga atcttgaaaa tggggttatc tattcaaaaa atattgcaaa
     3361 gcaattgatc gctaaagacc ctaaaaacaa ggaaacctat gaaaacaacc taaaagctta
     3421 cgttgagaag ctagagaagc ttgataagga agcaaaatca aaatttgatg ctattgctga
     3481 caataaaaag ctaatcgtca caagtgaagg ctgcttcaaa tacttctcaa aagcttacgg
     3541 tgtcccatca gcctacatct gggaaatcaa cactgaagaa gaaggaactc cggatcaaat
     3601 ttcatcattg atcgaaaaat tgaaagacgt taagccatca gcgctttttg ttgagtcaag
     3661 tgttgacaga cgtccaatgg agactgtttc taaggacagt ggtattccga tctatgcaga
     3721 aatctttact gactctgtag ccaaaaaagg ccaagatgga gacagctact atgccatgat
     3781 gaaatggaac cttgataaaa tttctgaagg cttagcaaaa taatataaca ataaagcaca
     3841 gcagcttctg gtgttgtgct ttgtttgtat taaggagaaa aaatgattga tacgcaaaat
     3901 ctttcggtta gctataacgg taacgtaaaa gccttagaca atatctcact acaaatcaaa
     3961 ggaccagcta tcgttgggat tatcgggcca aatggtgcag gaaaatcaac cttgatgaag
     4021 gctatgctca atcttttaga ttatagtggc caagtaactg ttgatcaaaa ggacggtcga
     4081 aggctggggc atacgattgc ttatgtagag cagcgcagca tgattgacta caactttcca
     4141 attacggtga aggagtgcgt ctcattaggg acctacacta ggctagggct ttttcgtcgt
     4201 gtcggaaaaa aagaatatga tcaggttgac cagctgctag agcaggttgg gcttgctggc
     4261 tttggtaatc gtccgataaa atctctttct ggtggtcagt ttcagcgtat gctagtagct
     4321 agatgcttga ttcaggagtc agactatatt tttcttgatg agccctttgt tgggattgat
     4381 tcggttagtg aaaaaatcat cattgacctg ctcaaggact tgaaaaaagc aggcaaaacg
     4441 attttaattg ttcatcacga tttaagcaag gtagagcatt actttgatga gttagtggta
     4501 ttgaacaaag agctgatcgc ttatggatct gttgatgagg tgttcactgt tgaaacccta
     4561 tcaaaggcct atggtgatca tctattctta ggaaagggaa tgttttaaat gtatttgaag
     4621 ttttttgagg gcctgatgtc ctatcatttt ttacaaaatg cccttattac agccgttgtt
     4681 attggtattg tatcaggagc agtaggctgc tttattatcc ttaggtccat gtcattaatg
     4741 ggtgatgcga tttctcacgc tgttttgcca ggagtagcct tgtcctttat tttagggatt
     4801 aatttttttg taggggctat tgtctttggc ttgctagcct ctgttatcat tacctacatc
     4861 aaggaaaact ctgttatcaa gggagacaca gcaataggga taacctttag ctcttttctt
     4921 gccttagggg ttattctgat tgggattgct aatagctcaa cggatctttt tcatatcctc
     4981 tttggaaata tcctagcagt gcaagacagt gacaaatgga ttacgatcat tgtttcggtt
     5041 tttgttttgg ctattattgt cctcttcttt aaggaattac tcattacctc ctttgatcct
     5101 gtgctagcaa ggtctatggg aatgaaggtc actgcttatc attatctgtt gatgattttg
     5161 ttgaccttgg tttcggtgac tgctatgcaa agtgttggta ccattttgat tgtggcgatg
     5221 ctgattacgc cagcggctac agcgtatttg tatgctaaca gcctaaaggt aatgctggtt
     5281 atctcctcat gcttgggagc tatgacctct gtgttggggc tctatttggg ctacaccttt
     5341 aatattgcag caggctcaag cattgttttg acctcggctg tggtgtttct gattagcttc
     5401 tttgtttcgc ctaagcaggg ctactttaaa aagcattcct agtaaaccat agctggctgt
     5461 gaatggatag ctgctaatga tatgatcaat aggctagctt ctttatttaa ttgatagcaa
     5521 aaaatcacga ccagctcttg aatcggtggc ttttccgata aggagctggt cgttttattg
     5581 ttgttgtagc ttagaggcta ttttttaaag gagtaatcct taacaatgtc aatagcatta
     5641 atagtgatgt tctctattgg tttgtcattt gggccgactg ggctggcagc tattttatca
     5701 acgatatcca taccctcaat aacctgacca aaaacggtat agccaccatc taggctagga
     5761 ttaccccctt cttcgtagga gtcaatgatt ggcttagagt aattatcaat tgataaggcc
     5821 ttggcttggt tgagcttgct ttgattgatg aagaactggc tgccattagt atctgcaccg
     5881 gcatttgcca tagcaagagc ccctcgaatg ttatataaaa atggtgagat ttcattagca
     5941 aagccttgtc ccgcatcttt tttgctgtcc ttgcccttcc aaatggattc tccgccagat
     6001 ccatctccct ttggatcacc ggtttgaatc ataaagttat taatcacccg atggaacaaa
     6061 agtttgtcgt aatagccttc cttggcgtgt gttaaaaagt tttcaacagc aagcggtgca
     6121 tacttgggga agagcttgag ggtgatatcg ccctgattag ttttgataat gaccttagct
     6181 tcgtctttgt cgacttcttt atttaattgt ggaaactgat cagcgtcagc cttgagtgct
     6241 tttttgattt ttgcttcata agcctttgct gctgtctcgc tttcctctct agcgattttt
     6301 tcatcgacgt attcatcacc tttaatagca cgatcaatgg actcacagcc acttaagcta
     6361 agcaaagcaa gaccgattaa gccaaaagat agtagttttt tcatgtgtac tccttagaac
     6421 aatttctttt attttaacat aaaatgactt ggaaaataaa gctaaagggc attgagacga
     6481 agtctatttt ttaactattt ctaagcttct ctaagtcctc ctgagaaacc ttgaaggtga
     6541 cttgcccggt ctgcatatca acgatagcct tgacttcaac tcctttggga attagcttgc
     6601 catgccccat atcaatttgc aggggaagct taccataggt caaggtgtta aattcttttt
     6661 ccatcttcaa ctcctatttg ttcttatgat tgacattata gcataaaatc aagcagcttc
     6721 atctatttat tgagaatttt aatgtcatct ttcataacga ttaaaaaatg ttataataag
     6781 gctatggcta gaagaactca acgacaaaaa aatcccccta agagacgttt aacaaaggca
     6841 gagcttgaaa agcaaaaggc tattaagaga atgattgctt ctttctcctg cgctttattg
     6901 cttgtttttg ccatgcttcg cttaggtgcg cttggggtta ccttatataa tcttattcgc
     6961 tttatggttg gcgacttagc caatctcttg atgttggcgg tcctttttta cctctttttc
     7021 ttcaagtggc tcaggcaaaa agatggcctt atcgctggct ttatcatctt gtttttaggg
     7081 cttctggttg aatggcatgc ctatcttttc tcattgcctc agctagctca tcaggctatt
     7141 gttgctggga ctatccagct aatcaccaat gacctgctag cctttaaggt tagcgagttt
     7201 gttggtggtg gtatgcttgg ggccatgctg tacaagccta tttccttctt gttttctaat
     7261 attggctctt attttattgg ttttttgttt atcctgctgg gcttgttttt aatgacccct
     7321 tgggatattt atgacgtcag tcattttgtt aagacgcttt ttgaaaagct atccctggcc
     7381 tatcaagaaa acaaggaaaa gcggtttgtt gagcgagaaa agcaacgatt gctggctgaa
     7441 gaggagcgtc tagcaagaga ggccttggag gagcaagaat atctggccaa tcaagcgatt
     7501 aatcctgaga caggtgagct tttagcagag ccagaagacc tattgatgga gatggctgat
     7561 cagaaggagt ctgaagcatt ttttgagccg gaaattctgg cctatgactc acaccctgct
     7621 gatgatgagc ctgaggcatt tggagatgaa gaggagtctg taccagaagc ccctctaacg
     7681 ggtgcttcag caatcgcagg agaggcgccg ctgtcagatg atgaggagct gtcagtggag
     7741 gtcgatttca cgccaaagac caatctgctt tacaagctgc cgacgataga gctgtttgct
     7801 gctgataagc ctaaaaatca attcaaggaa aagtaccttg ttcgtcaaaa tatcaaggta
     7861 ttagaggata ccttcagaag ctttggaatt gacgtcaagg tggagcgggc agagattggg
     7921 ccatctgtaa ctaaatacga ggttaagccg gctgttggtg ttcgtgtgaa tcgcatttcc
     7981 aatttagctg atgacttggc cttggccttg gcagccaagg acgtacggat tgaagctccg
     8041 atccctggca aatcccttgt gggtatagag gtaccaaatt cagaggttgc aacggtttct
     8101 ttccgcgagc tttgggagca atccaacaca tctgatgaca aattattgga aattcctctt
     8161 ggtaaggctg tcaacggtag tgccagaagc tttgatttga cccgcatgcc tcatttgctg
     8221 gtggctggct caacaggatc agggaaatct gttgcagtca acggtattat ctccagtatt
     8281 ttaatgaagg ctagaccgga tcaggtcaaa ttcctaatgg tcgatccgaa aatggttgag
     8341 ctgtctgttt ataatgacat tcctcacctg ttaatcccgg tggtcaccaa ccctcgtaaa
     8401 gcaagcaaag cgcttcagaa ggttgttgat gagatggaaa atcgctatga gctgttcagt
     8461 aaggtcggtg tccgaaatat tgcaggctac aatgccaagg ttgaagccta caacaagcaa
     8521 tctgagcaaa agcaaatccc tttgccgatg attgttgtta ttgttgatga gctagctgat
     8581 ttgatgatgg tggctagtaa ggaggttgag gatgctatta ttcgtcttgg gcaaaaggcg
     8641 cgtgcagcag gtatccatat gattttagct actcagagac cttctgttga tgttatttct
     8701 ggattgatta aggctaatgt tccatcacgt attgcctttg cggtttcatc aggaacagat
     8761 agtcgcacca ttcttgatga aaatggcgct gaaaagctgc ttggtcgcgg ggacatgctc
     8821 tttaagccga ttgatgagaa tcaccctgtg cgtctgcaag gctcctttat ttcagatgat
     8881 gatgttgagc gcattgttag ctttatcaag gagcaggcag aggctgatta tgatgattat
     8941 tttgatccgg gtgaggttag tgactctgat tatggcagca gcggagctcc tgagggtgat
     9001 cccctttttg aggaagcaaa ggctcttgta ttggaaacgc aaaaggcaag cgcctcgatg
     9061 ctccaaaggc gtctatcggt tggctttaac cgagcaactc gactaatgga cgaattagaa
     9121 gaggccggtg tcattggtcc agctgagggg actaagccaa gaaaggtact gcaaaccaat
     9181 taaaaaagag ctcatctaaa ggctcatcat aaaacaaacc cgtaccaagc taagcttaac
     9241 catgtggctt gatacgggtt tttgatatgc tgctttgaaa aagtcccact caagcagaaa
     9301 actcaaagac agcttcattt tgagtgatag tgctagagct aattggcaga tctaatctg
//
LOCUS       DARYXW010000074         9338 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.074, whole genome shotgun sequence.
ACCESSION   DARYXW010000074 DARYXW010000000
VERSION     DARYXW010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9338)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9338)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9338
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.074"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            25..261
                     /locus_tag="TV191_001504"
     CDS             25..261
                     /locus_tag="TV191_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEL1508004.1"
                     /translation="MEVIRTLLMFFSHLLFIGISYQLLISLVDWSKFIHYRPENMGRL
                     RLLVLFLAIASGYLVSRFMLELIQISQYLLYDFH"
     gene            325..1596
                     /gene="murA"
                     /locus_tag="TV191_001505"
     CDS             325..1596
                     /gene="murA"
                     /locus_tag="TV191_001505"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEL1508005.1"
                     /translation="MDKIIIEGGSTRLEGEVTIEGAKNAVLPLLAATILPSTGKTVLR
                     NVPILSDVFTMNYVVRGLNIDVDFDEAANQITVDASGDILDVAPYEYVSQMRASIVVL
                     GPILARNGHAKVSMPGGCTIGSRPIDLHLKGLEAMGAEITQQGGDITAKAERLKGAMI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAQLLNKMGAKVRGAGTETLT
                     ITGVTSLCGVEHDVVQDRIEAGTFMIAAAMTSGNVLIRDAVWEHNRPLISKLMEMGVS
                     VVEEDAGIRVQADVTKLRPVTVKTLPHPGFPTDMQAQFTALMAIVKGESTMVETVFEN
                     RFQHLEEMRRMGLQSEVLRDTAMIHGGHELQGAPVMSTDLRASAALILTGMVAKGRTT
                     VNKLNHLDRGYYQFHEKLAKLGANIQRISEE"
     gene            1600..1788
                     /locus_tag="TV191_001506"
     CDS             1600..1788
                     /locus_tag="TV191_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEL1508006.1"
                     /translation="MTNGWRYVINQLMLIIAIGLLGLFCLALGLMIGYSLIGDGQNPL
                     AILSPDKWAELIHKFTGK"
     gene            1820..2698
                     /locus_tag="TV191_001507"
     CDS             1820..2698
                     /locus_tag="TV191_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL1508007.1"
                     /translation="MIKKKKDIRLLNAFLALLLVLGTGYLAGHDDLAADNPIKQVYQR
                     ILGSDTQQAGLPKASRDWDTPSKALADSVMTATIKQQLGDVITWNGTGAYIINHNKTT
                     LNAKVASLPYANNKTKMVQGQSVPTVANALLTKSTRQYQKRNDTGNGYSSWKPAGWHQ
                     VQGLKGRYSHAVDRGHLLGYALVGGLKGFDASMANPSNIATQTAWANQAANERSTGQN
                     YYETKIRKALDSNKRVRYRVTLLYEGNNLLASGSHLEAKSSDGSLEFNVFIPNVQAGL
                     QIDYQTGQITVASSQP"
     gene            2712..2870
                     /locus_tag="TV191_001508"
     CDS             2712..2870
                     /locus_tag="TV191_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508008.1"
                     /translation="MAKADHVASHHGREALVLVVPQRKVLTIFGLVALVEKQIGPLVE
                     APSMPAPD"
     gene            3610..4653
                     /gene="pheS"
                     /locus_tag="TV191_001509"
     CDS             3610..4653
                     /gene="pheS"
                     /locus_tag="TV191_001509"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEL1508009.1"
                     /translation="MDLQAQLEELKTKTQEALKQLNGDHSKELQELRVAVLGKKGTLT
                     ELLKGLKDLSNDLRPVVGKQVNELRDFLTQAFEEQAKVVEAAKIQAKLDSESIDVTLP
                     GRQMKQGYRHVLTQISEEIEDIFLGMGFQIVDGFEVEKDYYNFERMNLPKDHPARDMQ
                     DTFYITEDILLRTHTSPVQARTLDQHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQI
                     EGLVVGKSISMGDLKGTLEMIIKKMFGKERKIRLRPSYFPFTEPSVEVDVSCFKCGGK
                     GCNVCKKTGWIEILGAGMVHPSVLEMSGVNAQEYSGFAFGLGQERIAMLRYGINDIRG
                     FYQGDSRFSKQFK"
     gene            4843..7248
                     /locus_tag="TV191_001510"
     CDS             4843..7248
                     /locus_tag="TV191_001510"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEL1508010.1"
                     /translation="MLVSYKWLKKLVDIDVSPAELAEKMSTTGIEVEGITSPSEGLSK
                     LVVGHIVSCDAVPETHLHLCQVNTGDDELRQIVCGAPNVKAGINVIVALPGARIADNY
                     KIKKGKIRGMESLGMICSLQELGLPDAIIPKDFSEGIQILPETAAAGDSIFPYLDLDD
                     NIIELSITPNRADALSMRGVAHEVAAIYGKSVSFPEKPLIESAKAAADSLEVAIDSDK
                     VLTYASRIVENVTVKPSPQWLQNLLMNAGIRPINNVVDVTNYVLLYFGQPMHAFDYDT
                     FADHKLLARDAREGERLVTLDGEERVLTTDDIVITVADQPVALAGIMGGKSTEITASS
                     KTVVLEAAVFNGKSIRKTSSRLSLRSESSSRFEKGINHDTLVEALDFAAAMLEELAGG
                     TVLAGRLQAGSLPTNPVEVSTSLDYVNVRLGTALSFTDIEGIFARLGFGISGTAEHFT
                     VSVPRRRWDITIPADLVEEIARIYGYDRLPTTLPEAAGTAAELTKTQALRRQLRGLAE
                     GLGLTEIISYALTTPEKALEFAMKPSQLTELMWPMSVERSVLRQSMVSGMLDTLAYNV
                     ARQQHNLAVYEIGKVFEQEGNPKETLPTELNHFAFAITGLVADKDFQTQAQAVDFYHT
                     KGILECLFDKLGLSVDYIPTKEMASMHPGRTARIQLGDQVIGFVGQVHPQAAKAYHIP
                     ETYVAELDLTAIEAALPAHHAFVEITKYPAMVRDIALLVDASTSHQAILSAITSAKVK
                     RLTEIKLFDIYAGAIIAAGKKSMAYSLTFQNPTDNLTDEEVAGYMEKITKALVEKVGA
                     EVR"
     gene            7483..8559
                     /locus_tag="TV191_001511"
     CDS             7483..8559
                     /locus_tag="TV191_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1508011.1"
                     /translation="MFLALNEIKQAKLRYGLIMGLLCLVAYLMFFLSGLAFGLMQENR
                     SAVDSWQADTVLLSKDADANLSLSSLKTSQLKEIKADEVTPLAQLNTVAWSTQAPTEE
                     DKEKISFFGIERESFLKPTITKGRLFKSDKEVVIDQSLAEKGGFKLGDQLRVSASNQT
                     YTIVGYTKNASFNVSPVAYLNLTAFQGLLYGQEAGAQDPNVNAFIIKGKLADYPKEEL
                     QQLTIGDFINKLPGYSAQLLTFGFMIGFLVLISAIIIGIFMYVLTIQKAPIFGIMKAQ
                     GIANRTIANAVLSQTFVLSLLGSSLGLLGTWLSSLVLPATVPFQSNWYLYALILVAMV
                     VFAVLGTLFSVFTIVRIDPLEAIG"
     gene            8569..9273
                     /locus_tag="TV191_001512"
     CDS             8569..9273
                     /locus_tag="TV191_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1508012.1"
                     /translation="MTVLAFKQVTKSFKDGDQTIEALKKTDFAIKAGEFVALIGPSGS
                     GKSTFLTIAGGLQTPSSGQFLVNGKDYTNLSEKERSKLRFKDIGFILQASNLIPFLTV
                     KQQLELVDKLTKHKQEAKRQQLFEDLGIAKLANKLPQDLSGGERQRVAIARALYHDPV
                     IILADEPTASLDTEKAFEVVELLAKESKEKNKAIIMVTHDNRMIDYCDKVYRMQDGQL
                     SQDNHHIASNAAMTQN"
BASE COUNT         2649 a         1962 c         2213 g         2514 t
ORIGIN      
        1 ttagactttt gatataataa agctatggaa gtaattagaa ctcttttaat gtttttcagc
       61 catttattat ttattggcat tagttatcag ctactcatta gcctagttga ttggtcaaaa
      121 ttcattcatt accgaccaga gaatatggga aggcttcgct tgcttgtcct ttttttggca
      181 attgcctcag gctatttagt tagtcgcttt atgctggaat taattcaaat cagtcagtat
      241 ctgctgtatg atttccacta gagtaggcag tcaggaagta tgatataata ttagtacgat
      301 gaccagtagg aaatggagaa gcttgtggat aaaataatca tagaaggtgg gagcacacgt
      361 ttagagggag aggtaacgat cgaaggcgct aaaaatgccg ttcttccttt actagcagct
      421 actatcctcc cctcaactgg aaagactgtc ttgagaaatg tgccgattct ctcagatgtt
      481 tttacgatga actatgttgt gcgtggccta aatattgacg tcgactttga tgaggctgcc
      541 aaccagatta cagttgatgc ctcaggggac attttagatg ttgccccgta cgagtatgtc
      601 agccaaatgc gcgcctcaat tgtggtttta ggcccgattt tagctcgtaa tggccatgcc
      661 aaggtatcga tgcctggagg ctgtacgatt ggcagtaggc cgatcgattt gcatttaaag
      721 ggcctagagg ctatgggcgc tgagatcacc cagcagggtg gtgacatcac tgcaaaggct
      781 gagcgcctaa agggggcaat gatctatatg gatttcccat cagtgggggc tacgcaaaat
      841 ttgatgatgg cagcgaccct tgctgatggt gtgacagtca ttgagaatgc tgctcgcgag
      901 cctgagattg ttgacctagc ccagctgctc aacaaaatgg gggctaaggt tcgtggggca
      961 ggtaccgaaa ccctgaccat aacgggtgtc accagtctat gtggggttga gcatgatgtt
     1021 gttcaggatc gtatcgaagc aggtaccttt atgattgctg cagcaatgac ctccggtaat
     1081 gtgctgatta gagatgctgt atgggagcat aatcggccct tgatttctaa gctcatggaa
     1141 atgggagtgt ctgttgtcga agaggatgca ggcattaggg tgcaggctga tgtgactaaa
     1201 ctaaggcctg tcactgttaa aactcttcct cacccaggct ttccaacaga tatgcaggct
     1261 cagtttacag cccttatggc cattgttaag ggagaatcta cgatggtgga aacagtcttt
     1321 gaaaatcgtt tccagcacct agaagaaatg cgacgcatgg gcttacaatc tgaggtattg
     1381 cgtgatacag ctatgattca tggtggtcac gaattacagg gagcgcctgt gatgtcaaca
     1441 gacctgcgag ctagtgcagc cctcatctta acgggaatgg ttgccaaagg caggaccact
     1501 gtgaataaat tgaaccattt agatcgtggc tattatcagt ttcatgaaaa gcttgccaag
     1561 ctaggtgcca acattcagcg aattagtgag gagtagtcaa tgactaatgg ttggagatat
     1621 gtcataaatc agctaatgct aatcatagct attggactgc tcggactctt ttgtctggcg
     1681 ctgggactaa tgattggcta tagccttatc ggtgatggcc aaaatccttt agcgatttta
     1741 tcgccagata agtgggctga gctgattcat aaatttacgg gaaagtaggc atggcctgct
     1801 ttttatgata agaggaaaga tgatcaaaaa gaagaaagac atcaggctgc ttaatgcctt
     1861 tttagcgctc ttgcttgttc ttggaacagg ttatttggca ggacatgatg acctagcagc
     1921 tgataacccg atcaagcagg tctaccaaag gattcttggc tctgacacgc agcaagccgg
     1981 gctaccaaag gcaagccgag actgggacac tccctccaag gccttggcag attcggtcat
     2041 gacagccacc atcaaacagc aattaggtga tgtgattact tggaatggca ctggtgccta
     2101 tatcattaac cataataaaa cgacgctaaa tgcaaaggta gctagtctcc cctatgccaa
     2161 taataaaaca aagatggtac aagggcaaag cgttcctacc gtagccaatg ccctgctaac
     2221 caagtcaacc cgacaatatc agaagcgcaa tgacactgga aatggctata gctcatggaa
     2281 gcctgctggc tggcatcagg ttcaggggtt aaagggaagg tatagtcacg cagtggatag
     2341 agggcatctt ctaggctatg cgcttgttgg cgggctaaaa ggctttgatg cctcaatggc
     2401 taatcctagt aatatcgcta ctcaaaccgc atgggctaac caagcagcta acgagagatc
     2461 aaccggacaa aactattatg aaacaaaaat tcgcaaagcc ctagatagca ataagcgtgt
     2521 ccgctatcgt gtaactttgc tttatgaggg aaataatctc ttagcaagcg gcagtcatct
     2581 tgaggcaaag tcatcagatg gtagcttaga atttaacgtc tttatcccta atgtacaggc
     2641 tggattacag attgattatc aaacaggtca gatcactgta gcttcttccc agccttagtg
     2701 aggcacatca catggcaaaa gctgatcacg tagctagcca tcatggcaga gaagcattag
     2761 tccttgtagt ccctcaaaga aaggtgctaa caatatttgg tcttgtggct ttagtagaaa
     2821 aacagatagg tcctttagtc gaagcaccaa gcatgccagc tcctgattag gacaaatgtc
     2881 aaggctaagc ggtggtaagt taaagtctca caaaagacaa gactggactt ttggctatag
     2941 tcctttatga ctgatgccag ctgataatgg ctcaagatga ttgaggtttc tagcaatgct
     3001 tgtggctagc ctatcgtctt agttagcgct gattgatgag atgttgaaca gttcttgact
     3061 aaaagcatcc ctacccttac gcctacgtcc tggttagtga agaaataagc attgtcataa
     3121 aggcattttt ttgatacaat aaaagtaatt gaatagcagt ctatgagact agtactaata
     3181 gggaagttaa tagggaatgg gggtcgtgac tggaagcctt cttaatgaaa cgattaggaa
     3241 ttcactcaat caaggacgag gtaattaagg tctgacttgc tcagatgaaa acggatggta
     3301 ccgcgtgtca acgctccgct ttagatagga gccttgatac gccttttttg atgacgtgct
     3361 gttactatta gctatttaat cacaagcaag cactagccag ccaaaagtaa gtgatcacta
     3421 taagcataga aagataggag ctgtagctta tctagaaaag caagggtgat cagtcgtccg
     3481 cccaaaagtc tttcttagct tttgtgatgt gactagctga cctagctgct cacagcttag
     3541 cctaaaaggc ctattagcac aaggactgcc agcattaatg caatcatttt ccaaacagaa
     3601 gggaatatca tggatttaca agcacaatta gaagaactga aaaccaagac acaagaagcg
     3661 ctcaagcagc taaatggtga ccacagcaag gaattacagg agctgcgggt tgctgtcctt
     3721 gggaaaaaag gaacgcttac cgaactgctc aagggactaa aggatctctc aaatgacctg
     3781 cgtcctgttg ttggcaaaca ggtcaatgag cttcgtgact ttttgaccca agcctttgaa
     3841 gagcaggcta aggtggttga ggcagcaaag attcaggcca agctagattc tgaaagcatt
     3901 gatgtgactt tgccaggccg tcagatgaag cagggctatc gacatgtgct cactcaaatc
     3961 agtgaagaaa ttgaggacat tttcttgggc atgggctttc aaattgttga tggctttgag
     4021 gttgaaaagg attattataa ttttgaacgc atgaaccttc caaaggatca tccggctcgt
     4081 gatatgcaag acaccttcta tatcacagag gatattttgc tgcgcaccca caccagtcct
     4141 gtacaggcac gaacactgga ccagcatgat ttttcaaagg ggcctctcaa gatgatttca
     4201 cctggacgtg ttttccgtcg tgacaccgat gatgccactc attctcatca atttcaccaa
     4261 attgaaggct tagtcgttgg taagtctatt tctatgggag acttgaaggg gactcttgag
     4321 atgatcatta aaaagatgtt tggtaaggag cgtaagattc gcctgcgccc atcctatttc
     4381 ccttttactg agccatctgt tgaggttgat gtctcatgct tcaaatgtgg tggtaaaggc
     4441 tgcaatgtct gcaaaaaaac aggctggatt gaaattcttg gagctggtat ggtgcaccca
     4501 agcgttttag aaatgtcagg tgtgaatgcg caggagtatt caggctttgc ctttgggctt
     4561 ggtcaagagc gcatcgccat gctgcgctat ggtatcaacg atattcgagg cttctaccaa
     4621 ggagatagtc gcttttctaa gcagtttaag taatagtgat catatggtca aaaaccaaat
     4681 catcagtttg aaaaaagaac tgacgctcaa tctggagctg ttctttggat tagaatcaga
     4741 aaggaaaaag acgggtaaag agcaaagaag tgattggcta gcttatctca agcaggtgct
     4801 aggcagatct ctcatcagcg ctcactactc tattgaaggc ttatgttagt atcttataaa
     4861 tggttgaaaa aattagttga cattgatgtc tcaccggccg agctagctga aaaaatgtca
     4921 acaacaggta tcgaagtaga aggcatcacc agcccctctg aaggtttatc aaagctagtt
     4981 gttgggcata ttgtctcatg tgacgctgtt ccagaaacgc acctgcacct ttgtcaggtc
     5041 aacacaggag atgatgagct tcgtcaaatt gtctgcggtg cacctaatgt caaagcaggg
     5101 attaatgtga ttgttgcgct gcctggagct cgtattgcag acaattacaa gattaaaaag
     5161 ggtaaaatac gcggtatgga gtctcttggc atgatctgct cacttcagga gcttggctta
     5221 ccagatgcga ttattccaaa agatttttca gaaggtatcc agatcctacc ggaaacagca
     5281 gcagcaggtg atagcatttt cccttacctt gatttagatg acaatatcat tgagctttcc
     5341 atcacaccta atcgtgctga tgccttatca atgcgtggtg ttgcccatga ggtggcagct
     5401 atctatggca agtcagtgtc atttccagaa aagcccctta tcgaatccgc taaagcagca
     5461 gctgatagtc tagaggttgc tattgactct gacaaggtgc tgacctatgc tagtcgtatt
     5521 gttgaaaatg tcaccgtcaa gccaagtccg caatggctgc aaaatcttct gatgaacgct
     5581 ggcattcgtc caatcaacaa tgttgttgat gtgaccaatt atgtcttgct gtattttggt
     5641 cagccaatgc atgcctttga ttatgatacc tttgctgatc ataagctttt agcgcgtgat
     5701 gcgcgtgagg gagaaaggct tgtcaccctt gatggagaag agcgtgtgct aaccacagat
     5761 gacattgtta ttaccgtagc agaccagcca gtggctctag ctggtattat gggaggcaaa
     5821 tcaacagaaa tcaccgcctc ctcaaagaca gtggtgcttg aagcagcagt ctttaatggc
     5881 aaatcaatcc gtaaaacaag cagtcggcta agtcttcgtt cagaaagctc atcacgcttt
     5941 gaaaaaggga ttaaccatga cacgcttgta gaggccttag attttgcggc agccatgcta
     6001 gaagagctag ccggtgggac tgttttagca gggcgcttgc aggcaggctc actgcctacc
     6061 aatccggtag aggtttcaac cagccttgat tacgtcaatg tccgcttggg aacagccttg
     6121 agctttactg atattgaggg gatttttgca aggcttggct ttggtattag cggaactgct
     6181 gaacacttta ccgtttcagt gccacgacgc cggtgggata taacaattcc ggctgaccta
     6241 gtcgaagaaa ttgcccgtat ctatggctat gatcgattgc caaccacatt accagaagct
     6301 gctggcacag ccgcagaatt aaccaaaaca caggcccttc gtcgtcagct gcgtggtctt
     6361 gcagagggac tgggtttaac agaaatcatt tcctatgctc taacaacacc tgaaaaggcc
     6421 cttgaatttg caatgaagcc aagccagtta acagagctga tgtggccaat gtcagtcgag
     6481 cgctctgtcc ttcgtcaaag catggtatca ggtatgcttg acacccttgc ctacaatgtg
     6541 gcacgtcaac agcataacct tgccgtttat gagattggta aggtctttga gcaagagggc
     6601 aatcccaagg agacattacc aacagagctt aatcactttg cctttgctat cacaggctta
     6661 gtagcagaca aggattttca gacacaagcg caagcggttg atttttacca tactaaggga
     6721 atcctagagt gtctctttga taagctagga ctgtctgtgg attatatccc aacaaaggag
     6781 atggcgagca tgcacccagg acgtaccgca cgtattcagc taggagatca agtgattggc
     6841 tttgttggtc aggtgcaccc acaggctgct aaggcttatc atatcccaga gacctatgtt
     6901 gcagagcttg acctgactgc tatagaggca gctctaccag ctcatcatgc ctttgtggaa
     6961 atcaccaaat acccagctat ggtaagggat attgccttat tggttgatgc ctcaaccagt
     7021 catcaagcca ttctttcagc gatcacgtct gccaaggtaa agcgtctaac agagattaag
     7081 ctctttgaca tttacgcagg agcaattatt gcggccggta aaaaatcaat ggcctatagc
     7141 ctgaccttcc aaaatccaac agacaatctg actgatgagg aggttgccgg ctacatggag
     7201 aaaatcacca aggccttggt agaaaaggtt ggtgcagagg tgagataagg acgcttctaa
     7261 tgactagcta cctaaaaaaa gctcatttca aaggcttagc tgcaattgtt ctgttgcggc
     7321 tgagcttttt ttgatgctta gactgtcctt atcctatgct agttgcagca agggtttaga
     7381 gatgatttta tttaaattat cagtcaaaaa tattttttct aatcaaattc ctagctttat
     7441 ctgatctcct ctgctatact gtgcaataag taaggagatt atatgttttt agccctaaat
     7501 gaaataaaac aagctaagct cagatatggc ttgattatgg gactgctctg tttagtagcc
     7561 tatttgatgt tctttttatc cggtttagcc tttggattaa tgcaggaaaa tcgctcggca
     7621 gttgacagct ggcaggcaga tacagttctt ttgtcaaagg acgctgacgc caatctcagc
     7681 ctatcctctt taaagaccag tcagcttaag gagatcaagg ctgatgaggt cactccccta
     7741 gcccagctga atacagttgc ttggtcaacc caagctccaa cagaagaaga caaagaaaaa
     7801 atcagctttt ttggcattga gagagagtcc tttctcaagc ctacaatcac aaaaggaagg
     7861 ctatttaagt cagacaaaga ggtggtgatt gatcaaagcc ttgctgagaa aggaggcttt
     7921 aagcttggag atcagctgcg ggtatcggcc tctaaccaga cctataccat cgttggctat
     7981 accaagaatg ctagctttaa cgtgtcacct gttgcttacc tcaacctgac agcctttcag
     8041 ggcttactgt atggtcaaga agcaggcgca caagacccaa atgttaatgc ctttattatc
     8101 aaaggcaagc tagctgacta tcccaaggaa gagcttcagc agctaacgat tggcgacttc
     8161 atcaacaagc tgccgggcta tagtgcacag ctcttgacct ttggctttat gattgggttt
     8221 ttagtgttaa tctcagccat tatcattggt atttttatgt atgtgctgac cattcaaaag
     8281 gcaccaatct ttggtatcat gaaggcacaa ggcattgcta atcgtaccat tgcaaatgct
     8341 gtgctatcac aaacctttgt cctaagcctt ttgggcagca gccttggcct actaggcacc
     8401 tggctaagct cgcttgtctt accagcaaca gttccctttc agagcaattg gtacctatat
     8461 gcgcttattt tagttgctat ggtagtcttt gcagtattag gcaccctctt ttcagtcttt
     8521 acgattgtta gaattgaccc tctagaggcc attggttagg agaagaatat gacagtatta
     8581 gcatttaagc aggtcacaaa gtcctttaag gacggtgatc agaccattga agccctgaaa
     8641 aagacggatt ttgcgattaa agcaggcgag tttgtcgccc ttataggtcc atcaggctca
     8701 ggcaaatcaa cctttctgac cattgcaggt ggtctacaaa caccaagctc aggacaattt
     8761 ttagtcaatg gcaaggatta caccaaccta tctgaaaagg aacgatcaaa actacgcttt
     8821 aaggacattg gctttatcct gcaggcttct aatttgattc catttttaac cgtcaaacag
     8881 cagctagaat tagttgacaa gttgaccaag cacaagcagg aagcaaagcg tcagcagctc
     8941 tttgaggact tgggaatcgc taagctggct aataagctgc cccaagattt atccggtggc
     9001 gagcgtcagc gtgttgccat tgccagagcc ctataccatg atcctgtgat cattttagca
     9061 gatgagccga ctgccagtct ggatactgaa aaggcctttg aggtcgttga acttctagct
     9121 aaagaaagca aggaaaaaaa caaggcaatt atcatggtaa cccatgataa ccgtatgatt
     9181 gactattgcg ataaggtcta tcgcatgcag gacggccaat tgagtcaaga caatcatcat
     9241 atagctagca atgccgcaat gactcaaaac taatcgaata ggaaaagctc tgctctagcg
     9301 atatagcagg gctttttagc tgctctaaat tatctcaa
//
LOCUS       DARYXW010000075         9170 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.075, whole genome shotgun sequence.
ACCESSION   DARYXW010000075 DARYXW010000000
VERSION     DARYXW010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9170
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.075"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            101..1027
                     /locus_tag="TV191_001513"
     CDS             101..1027
                     /locus_tag="TV191_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEL1508013.1"
                     /translation="MEKIIITATAESIDQVKSLLAAGVDRIYVGEADYGLRLPHAFSY
                     DDLRQIAALVHKAGKELTVACNALMHQGMMDRIKPFLDLMKEIAVDYLVVGDAGVFYV
                     NKRDGYDFKLIYDTSVFVTSSRQVNFWGQHGAVESVLAREIPSEELFALADNLDYPAE
                     ILVYGASVIHHSKRPLLENYYHFTKIDDEVSRERGLFLAEPGDPDSHYSIYEDNHGTH
                     IFINNDIDMMTKLGELYEHGLTHWKLDGVYCPGENFVAITKLFIKAKALLESGQFTTE
                     LAQQLDAEVQGLHPVGRGLDTGFYDFDPKTVK"
     gene            1135..2421
                     /locus_tag="TV191_001514"
     CDS             1135..2421
                     /locus_tag="TV191_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEL1508014.1"
                     /translation="MSNVKKRPEVLSPAGTLEKLKVAIDYGADAVFVGGQAYGLRSRA
                     GNFSMEELQEGIDYAHKYGAKVYVAANMVTHEGNELGAGEWFRQLRDMGLDAVIVSDP
                     ALIVICSTEAPGLEIHLSTQASSTNYETFEFWKELGLTRVVLAREVNMAELAEIRKRT
                     EVEIEAFVHGAMCISYSGRCVLSNHMSHRDANRGGCSQSCRWKYDLYDMPFGSERRSL
                     KGEIPEEYSMSSVDMCMLEHIPDLIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     MESPEAFYAIKDDLIDELWKVAQRELATGFYYHIPTENEQLFGARRKIPQYKFVGEVV
                     SFDDDSMTATIRQRNVIVEGDRVEFYGPGFRHFETVIKDLHDADGNKIDRAPNPMELL
                     TISLPQAVKPGDMIRACKEGLVNLYQKDGTSKTIRA"
     gene            complement(2517..2842)
                     /locus_tag="TV191_001515"
                     /pseudo
     CDS             complement(2517..2842)
                     /locus_tag="TV191_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677676.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2977..3189
                     /locus_tag="TV191_001516"
     CDS             2977..3189
                     /locus_tag="TV191_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEL1508015.1"
                     /translation="MSEFTFKIEEHLLTLSESDKGWTKELNRVSFNGAEPKWDIRTWS
                     PDHTKMGKGITLTNEEFKTILDAFRR"
     gene            complement(4085..4225)
                     /locus_tag="TV191_001517"
     CDS             complement(4085..4225)
                     /locus_tag="TV191_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508016.1"
                     /translation="MKKEYISYLSAAIFILYALLSLKWIFFVLGVILLIIGLADRFRS
                     KP"
     gene            complement(4588..6081)
                     /gene="lysS"
                     /locus_tag="TV191_001518"
     CDS             complement(4588..6081)
                     /gene="lysS"
                     /locus_tag="TV191_001518"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEL1508017.1"
                     /translation="MSNQHIEELNDQQIVRREKMAALAEQGIDPFGKRFDRTTNSGEL
                     KEKYSDKTKEDLQELQATAIIAGRLMTKRGKGKVGFAHLQDRQGQIQIYVRKDSVGDD
                     NYDIFKKADLGDFIGVEGDIMCTDMGELSIKATKLTHLSKSLRPLPEKFHGLTDIETI
                     YRKRHLDLISNRSSFERFITRSKMISEIRRYLDGLGFLEVETPVLHNEAGGAAARPFI
                     THHNAQDIDMVLRIAPELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYE
                     AYADYLDMMTLTEGIIQHAAKAVKGEGPIDYQGTEIKLHEPFRRVHMVDAIKEVTGID
                     FWPEMTFEEATALANEKHVPVEKHFTSVGHIINAFFEAFVEDTLIQPTFVYGHPVEVS
                     PLAKKNPEDSRFTDRFELFIMTKEYANAFTELNDPIDQLSRFKAQAAAKELGDDEATG
                     IDYDFVEALEYGMPPTGGLGIGIDRLCMLLTNTTTIRDVLLFPTMKP"
     gene            6424..7901
                     /locus_tag="TV191_001519"
                     /pseudo
     CDS             6424..7901
                     /locus_tag="TV191_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677680.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
     gene            8213..9118
                     /locus_tag="TV191_001520"
     CDS             8213..9118
                     /locus_tag="TV191_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEL1508018.1"
                     /translation="MISAIVFDVDDTIYDQQAPYRIAMEKCFPDFDMSLINRAYIRFR
                     HYSDVGFPRVMSGEWTTEYFRFWRCRETLLEFGYRDIDQATGVHFQEVYEHELQHITM
                     LDEMRMTLDFLKSKNVPMGIITNGPTEHQLRKVRKLGLYDYVDPKRVIVSQATGFQKP
                     EKEIFNLAAEQFDMNPATTLYVGDSYDNDVMGAKNGGWHAMWFNHRGRSLKPGTRPIY
                     DVAIDNFEQLFGAVKVLFDLPDNKVIFDINDKKNPVLQLGLNNGLMMAAERLLESNMS
                     IDKVVILLRLNKQQERVLRMKYANR"
BASE COUNT         2533 a         1730 c         2097 g         2810 t
ORIGIN      
        1 ttttttttga aggcttctcg ttataggcct tggtataggc gttaagattt tgaatgaatc
       61 atttttgaaa gcctaagaaa tttggtataa tatcccttgt atggaaaaaa taattattac
      121 agccacagca gaaagcattg accaagtcaa atcgctttta gctgcaggtg ttgatcgtat
      181 ttatgtaggc gaagctgatt atggcttgcg tcttcctcat gctttttctt atgatgactt
      241 gaggcagatt gcagcgcttg ttcacaaggc gggcaaggag ctaacagttg cttgtaacgc
      301 tctgatgcat cagggcatga tggatcgtat aaagcccttt ttggacctta tgaaggagat
      361 tgctgtcgat taccttgttg ttggtgatgc cggtgttttt tatgtgaata aacgagatgg
      421 ctacgacttt aagctgattt atgatacttc ggtttttgtt acctcaagcc gtcaggttaa
      481 tttttggggg cagcatggcg ctgttgaaag tgttttagct agagagattc cctcggagga
      541 attatttgcc ttggctgaca atcttgacta cccagcagaa atattggttt acggggcctc
      601 tgttattcat cattctaaga gaccgctcct tgaaaattat tatcatttta ccaaaattga
      661 tgacgaggtc agtcgagagc gtgggctttt cttagcagag ccaggcgatc ctgatagtca
      721 ttattctatc tatgaggaca atcatggaac tcatattttt attaacaatg acattgatat
      781 gatgactaag ctaggcgagc tatatgagca tggcctgaca cattggaagc tagatggtgt
      841 ttactgtcct ggtgagaatt ttgtggccat taccaagctg tttataaaag caaaggcttt
      901 gctggagtct gggcaattta ccacagagct agctcagcag cttgatgcag aagtgcaagg
      961 gcttcaccct gtagggcgtg gtctggatac aggcttttat gattttgatc ctaaaacagt
     1021 caaataagct ataacttgac ttgtcctgat taaggttact atttcaaggc atgacaagtt
     1081 aatcattcaa agatgttaca tcttacctat cttgaaaata gaaagaataa caacatgtca
     1141 aatgtaaaaa aacgtcctga ggtgctgtcg cccgcaggaa cacttgaaaa attaaaggtt
     1201 gccattgatt atggcgctga tgcggttttt gttggtggac aggcctacgg gctaagaagt
     1261 cgcgcaggaa acttctctat ggaggaatta caagagggga ttgactatgc tcacaagtat
     1321 ggggctaagg tctatgttgc tgccaatatg gttacccatg agggcaacga gcttggggct
     1381 ggtgagtggt tccgtcaatt gcgtgatatg gggcttgatg cggtcatcgt ttcagacccg
     1441 gcccttattg tgatctgctc aacagaagca ccaggacttg agattcatct atcaactcaa
     1501 gcatcatcaa cgaactatga aacctttgaa ttttggaagg aattaggcct aacgcgtgtc
     1561 gtgctagcac gtgaggtcaa tatggcagaa ttggctgaga ttcgaaagcg cacagaggtt
     1621 gagattgagg cctttgtaca tggtgccatg tgtatttcct attcagggcg ctgtgttctc
     1681 tctaatcaca tgagtcaccg agatgccaat cgcggaggct gctcacaatc ctgccgctgg
     1741 aagtatgatt tgtatgatat gccttttggc tcagagcgtc gttccttaaa aggagagatt
     1801 ccagaggaat actccatgtc ctcggttgac atgtgcatgc tggagcatat ccctgatttg
     1861 attgaaaatg gagttgatag cttgaaaatc gaagggcgca tgaagtctat ccattatgtg
     1921 tcaacagtga ccaattgcta taaagcagct gttgatgctt atatggaaag tccagaggca
     1981 ttttatgcta ttaaggacga ccttattgat gagctttgga aagtggctca gcgtgagcta
     2041 gcaactggct tttactacca tattccaact gagaatgaac agcttttcgg tgcgcggcgt
     2101 aagattccgc aatacaaatt tgttggggag gtggtttcct ttgatgatga cagcatgaca
     2161 gccactattc gccaacgtaa cgtcattgtt gaaggagaca gggttgagtt ttacggaccg
     2221 ggcttccgtc attttgaaac agtgatcaag gatttacatg acgctgacgg caataaaatt
     2281 gaccgtgcgc caaacccaat ggagctctta accatctcct tgccacaggc tgtcaagcca
     2341 ggagatatga ttagggcctg taaagaagga cttgttaacc tctatcaaaa ggacggaacc
     2401 agtaagacca taagagccta gcaccactag actaagcaat aggatttgac caattacttt
     2461 tgacacagag aagtgataag gttaggtctc ctttactcct gattagggta ctgagtctat
     2521 ggcttttctt tggtgctggt gcgtgtatga ggtactaagc tagccttatc aatatctgct
     2581 aaaaaaataa tgcagtcagg ttttgattgg tattttttaa gaccaattga ccggttagct
     2641 gatcgtattt tttaatgtgc ccagtgaagc ttttggcttg atagatcaca tgaattggaa
     2701 tctccttgac ctgtgcctct ttgatggtgg taatgatctg gttggccttg aggttaacgg
     2761 gagaagcctt ggcttttttg ggaggctgat tgtcaataaa gccgatcaag gctgattgca
     2821 gctgcttcat cattgatttc atagctattg tcctcaaaca ttgatagaat agtttgatag
     2881 tattttacct taaactatga tttttaaaaa gaatttactg ttttgcattc aatttttaat
     2941 attattttcg aatagataga tgaggaggaa aatataatgt cagaatttac atttaagatt
     3001 gaggagcatt tgctaaccct gtcagaaagc gataaggggt ggacaaaaga gctaaaccgc
     3061 gttagcttca atggagcaga gccaaaatgg gatatccgca cctggagccc tgatcacaca
     3121 aagatgggta agggcattac tctgaccaat gaagaattta agacaattct tgatgccttt
     3181 cgtcgttaag ccttagctta gtcatcaata acttcaatgt gagaagaacc ttttctaacg
     3241 aacagtatca accatcagtt actttgttct tgtaggaagg ttcttttgtt atctcttcaa
     3301 gtgagttttt aagagcaagg taaaagacta tcgtctagaa cccccttagc attcatagct
     3361 gctaccgcaa cgataaaagt taaaaaacaa actaactggg gatctggtat ctagaaagtt
     3421 aatctagtcc tcttagagct tttagtaact gttagtcact atttattggt gagaggaata
     3481 tatcacaatg ctccaatcga gccttggttt gggtgtttta agtccggatg ctatgagcta
     3541 aagtcatacc agacttgtga agagcctatc actgatagta atcgctatct ctacttttac
     3601 aatgatagtc atctttaaaa gcacatgaaa ggccctgccc ctcctttaag gaggaacaag
     3661 gcttctgttt aatcattatg agattagtat tcgcttaata ggaagtcact caagctcagc
     3721 gtctattttg agactgatgc ttctgtccta gccttaggct gctcatattc tgctctaaaa
     3781 tcatacggat tgtcctgatt tgctttagaa tagcatactt gttgagtcta ggtcccaagg
     3841 atcttgaatg actgacgttg aaggtgttta gctcctgtta tcttggtata agaaggtatg
     3901 accttttggt aattggattg tctattgtat ggttccaaga tgatgattgg catgcttggt
     3961 tgttgactgc aagctgatag ccttgtggga ggctttgctt tcataaggct taagggctat
     4021 ttttacttta atgtaaggct ccttggctgg cagctatcga gacttggaga tgatagaggg
     4081 ctagctaagg ctttgacctg aaacgatcgg ctagaccaat aatcaagagg atcaccccta
     4141 aaacaaagaa aatccatttc aagctgagta aggcataaag gataaaaata gcagctgaga
     4201 ggtaactaat gtattctttt ttcataagat gctccctatc tttttatact attgtagcat
     4261 aaaaatcagt ttaaatgctg atgaaatcaa tggctatttt ggctttcatt ggcctagtaa
     4321 aaaccgttta gcctagcagc atgtcatcat tgcaaacaaa aaagattgaa gaatcaagtc
     4381 taagagatga ttcttcaatc ctagtataca gacaagctaa ggacatcact tcaaaagtga
     4441 ggcttttaga gaagctaaag gcaactaatg actattagct aggcctagct atggaagtga
     4501 ttggtcatag tgatcattcg atctggataa gaggcttagg atcagctaga gaaagctgct
     4561 ttttaaacac tggtagctag tcgcttttta tggcttcatt gttgggaata acaaaacatc
     4621 gcgaatagtg gttgtatttg tcagcagcat gcagaggcgg tcaataccga ttccaagccc
     4681 gcctgttggt ggcataccgt attcaagagc ctcaacgaag tcgtagtcaa taccggttgc
     4741 ttcatcgtct ccaagctcct tggctgctgc ctgtgcctta aagcgtgaca gctgatcaat
     4801 tggatcattt agctcggtaa aggcattagc atattccttt gtcatgataa agagctcaaa
     4861 gcggtctgtg aagcgactgt cctcagggtt tttcttagca agcggtgaaa cctctacagg
     4921 gtgcccatag acaaaggttg gctgaattag ggtgtcctcg acaaatgcct caaagaaggc
     4981 attgatgata tgaccaacag aggtaaaatg cttttcaact ggcacatgct tttcgttagc
     5041 aagagctgtt gcttcctcaa aagtcatctc aggccagaag tcaataccag ttacctcctt
     5101 gatggcatca accatatgca cgcgtctgaa tggttcatga agcttgattt cagtcccctg
     5161 ataatcaatt ggtccctctc ccttgactgc tttagcagcg tgctgaatga ttccttcagt
     5221 tagagtcatc atatctaaat agtctgcata ggcttcatag acctcaatag aggtaaattc
     5281 tgggttatgt gtagcgtcca tcccttcatt acgaaagatc cgtccaattt catagacacg
     5341 ctccatgcca ccgacgatga ggcgcttgag atgcagctct ggtgcaatgc gaagcaccat
     5401 atcgatatct tgtgcattgt ggtgagtgat aaagggacga gcagcagcac caccagcttc
     5461 attatgaagg acaggtgtct ccacttctaa aaagccaagg ccatcgaggt aacgacgaat
     5521 ttcagaaatc atttttgaac gtgtgatgaa ccgttcaaag ctgctgcggt ttgaaatcaa
     5581 atccagatga cgcttgcgat aaatggtttc gatatcagtt aagccatgaa atttctctgg
     5641 tagcggacgt agagatttgg atagatgggt cagttttgtg gccttgatag acaactcacc
     5701 catatcagta cacataatgt cgccttcgac cccgataaaa tcaccaaggt cagctttttt
     5761 gaaaatgtca tagttgtcat caccaactga atccttacga acatagattt ggatttgccc
     5821 ttggcgatcc tgaagatgag caaagccgac ctttccttta ccacgcttgg tcatcagacg
     5881 accagcaata atcgcagtgg cttgaagctc ttgtaaatcc tctttggttt tgtctgagta
     5941 tttttccttt aattcaccag aattagttgt tcggtcgaag cgtttgccaa atggatcaat
     6001 gccttgctca gctaaggctg ccattttttc acgacggaca atttgttgat catttaattc
     6061 ttcgatgtgt tgatttgaca tgttttcctc caatactttt ccttcctatt gtaacataaa
     6121 agattataga atacacctat atttcgtggg aattctatca tcgaagcctc agatgatagg
     6181 cctttgactt gtatagataa attggttttg tctgagttgg tttttctgta taaataagct
     6241 attatttgtg agatcttact tgaattgaag gcttttgcta gttccaatag attatttttg
     6301 atgatatttg acaaaaaaac ttaaattgtg aaaaaatatt aatcgaaaaa atcaaaaaac
     6361 tctcaacgct aaggctagtc tttgtgcagt tgagggtttt tatcaggaaa ggatcataaa
     6421 gaaatggaaa cttatgatat acacgggaag ccttatcatc gaacgctgat gattatattg
     6481 ctgttggtgg gaacctttgc aggggtttta aaccaaacaa gcttggggac agctatacca
     6541 acattgatgg aaaattttaa ggtacctttg tcaacaactc agcaggcaac cacttggttt
     6601 ttgcttgcta atggcattat gatccctgtt tcggcctttt tagcaacgcg attttccact
     6661 aaaagactct acatgacagc ttatgctatt cttgtgagtg gcttgttact agcagctctg
     6721 gctccgactg ctcattgggg agttttttaa cagcacgtat cgttcaggct tgtgcagtgg
     6781 gcattaccat gcctttgatg caggtggtga tgatcaacgt ttttcctgca gagcagcgtg
     6841 gtgcagcaat gggaatcaat ggcttggtgg ttgggctagc tccggctgtt ggaccaacct
     6901 tgtcaggctg gattttgaaa aaggattttt cagtattagg catttattta ggctggcggg
     6961 ccatttttat cttgccttta gtgattttgc tgttggtttt aagcctgtcg cccttcatgc
     7021 tccgagatgt tatccctcag caggctgtta agcttgattc aacatctcta ggcttatcta
     7081 tcttagggct gggtgctttt ctctggggct ttacaaatgt tgcagcttat ggctggctag
     7141 atatggtgta cgtgatttta cctattttag tcggtattgg tggaatttac ctcttttcca
     7201 agcgtcagct acaattagag aagccctttt tagatattag agtctttcgc aacaagcaat
     7261 ttaccttgac aacaatagca attgccctaa cgatgatggc tatgatcggt gttgagatga
     7321 tgctgccgct gtatctgcaa aatgtcagag gcttatctcc attaaattcc ggaatggttt
     7381 tgttgccggg tgctttgatt atggggctga tcagtccagt ttctggccga atttatgaca
     7441 agatcggtgc tcgttatctg gcgctattag gctttaccat tttagctgcg gcgactctac
     7501 catttgtatt tctaaatgaa aatacctcac gctttttgat tactgttttg tatgccatta
     7561 gaatgtttgg catatcaatg attttaatgc ctttaactgc aagtgctatg aatgccttgc
     7621 catcgcatga atcggcgcat ggaacggcag ctaataatac tgtacgccag atctcctctt
     7681 ctattgttgt ggcggtgtta tcgagtgtga cacaaaacat tatcagcagc aaacagccgc
     7741 ctaaaatgct cctatccata caccctgagc aatacgctaa gaagcttcta gaagccaatt
     7801 taaatggctt tcatgcctct tttttccttg gctttatgtt tgcagtggta ggctttattg
     7861 ttgtgctttt cctacataag ggaaaggtta tcgagaaata gctcctgatt agtgtggtta
     7921 aaacaaatag gctaaaggcc tcacgccaaa cgcatgaaaa aacagctgtt tttgatagct
     7981 tttctgatta atgcactctt tttcaagaaa acttatggca caatgaagct aaatgtgagc
     8041 agttgatgat gtcaaaataa tggaaaatct attgaaaaat gtttgagtct agaaaattgt
     8101 tacctgcatt ttctttgtgt ctctagcatg ctaaaagcat gggctggttt gaaaagtcga
     8161 tgacaaaata gtataatgat aagcatatca acctagaaaa gaaaagagac tcatgatttc
     8221 tgcaattgtt tttgatgtag atgatacgat ttatgaccag caggcgcctt accgtatcgc
     8281 aatggaaaag tgctttccag attttgatat gtcattgatc aatcgagcct atattcgttt
     8341 tcgccattat tctgacgttg gatttccaag agtgatgtca ggtgagtgga cgacagaata
     8401 ttttcgattt tggcggtgtc gggagaccct gcttgagttt ggctatcgtg acattgatca
     8461 ggcgacagga gtgcattttc aagaggtcta tgagcatgag ctgcagcata ttaccatgct
     8521 tgatgagatg cgcatgacac ttgatttctt gaagtcaaaa aacgttccga tggggattat
     8581 cacaaatgga cctactgagc accagctaag gaaggtgcgt aagctagggc tatacgatta
     8641 tgttgatcct aagcgcgtga ttgtcagtca ggcgacaggc tttcaaaagc cagaaaaaga
     8701 gatattcaac ctagcagcag agcagtttga catgaaccct gcaacaaccc tctatgtcgg
     8761 cgactcttat gacaatgatg ttatgggagc taaaaatggt ggctggcatg ccatgtggtt
     8821 taaccacaga gggagaagtc taaagcctgg gacaaggcct atctatgatg tggccattga
     8881 taactttgag cagctgtttg gtgctgttaa ggtcttgttt gatctgccag acaacaaggt
     8941 tatttttgat atcaacgaca agaaaaaccc ggtgctgcaa ttaggactta acaatggttt
     9001 gatgatggca gcagagcgct tgctagaaag taacatgagt attgataagg ttgttatcct
     9061 gttacgcttg aataagcagc aagaaagagt gctgcgcatg aagtacgcta atagatagca
     9121 gttattgatt gaaaagcatg ctatgtttaa ttggcactcc aaaggctaga
//
LOCUS       DARYXW010000076         9157 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.076, whole genome shotgun sequence.
ACCESSION   DARYXW010000076 DARYXW010000000
VERSION     DARYXW010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9157
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.076"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            432..1385
                     /locus_tag="TV191_001521"
     CDS             432..1385
                     /locus_tag="TV191_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEL1508019.1"
                     /translation="MKAWQELTITVHREAEEAVSNLLIEAGSQGVAINDTADYIGQED
                     RFGELYPAVEQSEMVTITAYYPSSADIDDIRQTINQGLNRLKQCDVELGELTLTNQEL
                     AEEDWADNWKAYYEPARITHDLTIVPSWTDYEATAGEKIIRLDPGMAFGTGTHPTTKL
                     SLFALEQVLRGGETVIDVGTGSGVLSIASSLLGAKEVFAYDLDDVAVRVAKDNIALNQ
                     ATDNIHVAAGDLLKGLTQEADVIVANILADILVHVTADAYRLIKSEGYLIMSGIISEK
                     LDMVKQAALNAGFLLETHMLQGEWNALIFKKTDDLSGVIGG"
     gene            1385..2131
                     /locus_tag="TV191_001522"
     CDS             1385..2131
                     /locus_tag="TV191_001522"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEL1508020.1"
                     /translation="MQQYFIKGRAEKIVQLTDKDTIKHMFQVMRLTDKEELVLVFDDG
                     IKRLARVSDSSAYEVELIKELEENLEMPVEVTIASGFPKGDKLDVITQKATELGAAAI
                     WGFPADWSVVKWDSKKLAKKQEKLAKIALGAAEQSKRNRVPEIQLFDQKGELLKQLKQ
                     FDKCFIAYEEAAKAGERSTLARELAGLSPGQKVLFIFGPEGGISSKELASFKQAGAIT
                     VGLGPRIMRTETAPLYALSAVSYALELMSS"
     gene            2380..3384
                     /locus_tag="TV191_001523"
     CDS             2380..3384
                     /locus_tag="TV191_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1508021.1"
                     /translation="MVTIKDVARLAGVSPSTASRAINDSDMISQATKERVKKAMEALD
                     YSPNYSAQNLVKRKSNTVGIILPVREGQDSLGNNPFFMQIIQGIAAVCTDQGYMVALA
                     TGRSEAELLKNVQNMIRSGNIGKLIFLYSKTDDQVFDFVKRQRVDCVVVGQSTTKDPG
                     NAKFVNNNNHQAGYDAAAFLLQKGYEAIVYAYTDMAELVQAERYKGYAELMTSKALAA
                     QALCVTLKDDRKSQKQLLDQLAKRSKVAFVVCDDVLAIHLQRLIKQVAADTQLAIVSF
                     NNSVLAELASPALTSIAIFPYQLGEQAAELVLSSAAPSPQPVLVPHQIIERESTPFIV
                     "
     gene            3681..5867
                     /locus_tag="TV191_001524"
     CDS             3681..5867
                     /locus_tag="TV191_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEL1508022.1"
                     /translation="MKTSFKQFFSFEFWQKFGKCLMVVIAVMPAAGLMVSIGNSLPML
                     NQESQLLATLGNVIAQVGWAVIGNLHLLFALAIGGSWAKERAGGAFASGLAFVLINRI
                     TGAIYGVSSAMLTDPEAKIKSLLGTEMIVKDYFTSVLESPALNTGVFVGIIAGFVGAT
                     AYNKYYNYRKLPDVLAFFNGKRFVPFVVILRSALVALVLALIWPVIQSGINGFGMWIA
                     SSQDTAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYEVMTGAAAGTKVFGQ
                     DPLWLAWVTDLVNLKGSNASTYQHLMETVVPARFKVGQMIGATGTLMGVALAMYRNVD
                     ADKKHKYKMMFISAAAAVFLTGVTEPLEYMFMFAAMPLYLVYALVQGASFAMADLVNL
                     RVHSFGNIELLTRTPMAIKAGLGMDLINFVWVSILFAVIMYVIADFMIKKMKLATAGR
                     LGNYDADILENDDTKPLSQQSIDGQSQVVQIINLLGGRENIADVDACMTRLRVTVNDP
                     SKVGSEEHWKQAGAMGLIIKGSGIQAVYGPKADILKSDIQDLLDSGAVIPEPKPAQPA
                     ASSSQQTDFKNLTEAVLAVADGEVLPITAVSDQVFAAKMMGDGFAVEPANGAIYAPVT
                     GLVTHVFPTKHAFGLLTDSGLEVLVHVGLDTVDLNGEPFTVKVSEGQRVSAGDLLAEA
                     DLTAITAAGRKTTVVVAFTNTTSIKAVNLVATGQQKAKTLVAQVEL"
     gene            5945..6766
                     /locus_tag="TV191_001525"
     CDS             5945..6766
                     /locus_tag="TV191_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEL1508023.1"
                     /translation="MTKLLTLNTHSWMEANALKKLFDLAEHILAQNYDVICLQEINQL
                     IDSEAAVPLSGYQPIAGTPAIHQDNFALLLVNYLKKRGQSYYWSWAYNHIGYDIYHEG
                     VAILSKQPIQASDILVSAVADEYDYHTRRALLAKTTIDGREAAVVSLHLSWFDQGFVG
                     EWQRLEAALQQLACPVLLLGDFNNPSGQEGYEMILKSPLDLQDSHQAADYVFGDHSIV
                     AAIDGWEDNKEAFKVDHVFTSKVFTINSSKVTFDGGEAPVVSDHYGLEVDLSWKL"
     gene            complement(7062..7520)
                     /gene="nrdI"
                     /locus_tag="TV191_001526"
     CDS             complement(7062..7520)
                     /gene="nrdI"
                     /locus_tag="TV191_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEL1508024.1"
                     /translation="MTDLTLVFISLSGNTLSFVRRLSQYLAEKHHIQTKAINIKELHH
                     ETFPVKESFVAILPTYLEGGNGIDSGEVEILTNPLGDFIAAHDNAKRCLGIIGSGNKN
                     FNHQYCLTAKQYAKRFGFPMLGDFELRGTSADIERLAQVIVARLTDDQQS"
     gene            complement(7916..9100)
                     /gene="sezV"
                     /locus_tag="TV191_001527"
     CDS             complement(7916..9100)
                     /gene="sezV"
                     /locus_tag="TV191_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_038674722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface antigen transcriptional activator SezV"
                     /protein_id="HEL1508025.1"
                     /translation="MDTMSLVKSLQGCLKLSITVFDKDHQVTESFWNDDTFEFYYRFQ
                     AVLRQMDKEQATNLFFQGSYNELFLIYRYQDHYILIGPWRCNVLDKTFFKVAVADKDL
                     TKEEEEILYQALKHLPVYPLNAIRDLLIVVHYFFSGKIEDLLSPPLRHYIRDFSDNIE
                     VQKANMFVKKQESKVCLYNYEKNLSSIVQEGDVHKLKEIIFSLRNTFIPVVSGDTLRS
                     EKNYSIIAFDRLAQIAIQSGMDIADAYHSREEFMRDSELATSMPDVLKIRDASLVFYT
                     QKVSELRDNRWKHVSPTVNAIIQYISVNLHKSVTTAELAQHFNMSESKLRQIFKRDTG
                     LTIYQYTSNMKIEEAKTLLRSAYAINHISDVLGFTDPSHFSKFFKKHTGESPKTYQNR
                     KH"
BASE COUNT         2509 a         1872 c         2204 g         2572 t
ORIGIN      
        1 agctgtctgg aagatgaaag gctttttagc tatttcaaag gcttggagct tcaacaggcg
       61 aatcagctat tggtttttct ggatttacga gaaagagctg ctcttttttg atgtagctgg
      121 tataaaatat ggtaaaatag ggtctatcaa gagcctatct acctttagat tggctgagat
      181 ttgttaggca atgcgtccct gataaaggtt gggcttatgg gacaataggc cttggtgctg
      241 tgtttgtcct tagtatgaaa cctctgagac ggcagagcag gatccggttg gtttaggacc
      301 gcattagctt atcttacgat aaaaaagaag cttgaaagga aaggctgctt tgatctgata
      361 gagggtcact ggttttaggg tttaggctag gggcaagtga ccactgatga tatggcagca
      421 agggtatcgt tatgaaggca tggcaagagc tgacaattac agtccatcgt gaggcagaag
      481 aagctgtttc caatctgctg attgaggctg gcagccaagg agtcgctatc aatgacactg
      541 cagactatat cggtcaagag gaccgttttg gggagcttta tccagctgtt gagcagtcag
      601 aaatggttac tattacagcc tattatccaa gctcagctga tattgatgac atcagacaga
      661 ccattaatca gggcttgaac aggctaaagc agtgtgatgt ggagcttggt gagttaaccc
      721 tgaccaatca agaattggct gaagaggatt gggcggacaa ctggaaagcc tattatgagc
      781 ctgctcgtat cacgcatgat ttgacgatag tccccagttg gacagattat gaagccacag
      841 caggtgagaa gatcattagg cttgatccgg gtatggcatt tggaacaggc acacacccaa
      901 caactaagct aagcctgttt gccttggagc aggtgcttcg tggtggtgag acagttattg
      961 atgtggggac aggctcaggt gtgctatcga ttgctagctc tctgcttggc gccaaagagg
     1021 tctttgctta tgatttagat gatgtggcgg tgcgtgttgc caaagacaac attgccctca
     1081 atcaagccac tgacaatatc catgtagcag ctggagacct gctaaaaggc cttactcaag
     1141 aggcagacgt tattgtcgcc aatatcttgg cggatatttt ggtgcatgtg acagcagatg
     1201 cttaccgtct tatcaagtct gaggggtatc tgatcatgtc agggattatt tcagaaaagc
     1261 tggatatggt gaagcaggct gctcttaatg caggcttctt gctagagact cacatgcttc
     1321 agggcgagtg gaatgctctt attttcaaaa aaacagatga tttatcagga gtgattggtg
     1381 gctgatgcag cagtatttta ttaaaggcag ggcagaaaaa atcgttcagc tgaccgataa
     1441 ggataccatt aagcatatgt ttcaagtgat gcgcttgacg gataaggaag agctggtgct
     1501 agtctttgat gacggcatta aacgcttggc aagggtgtca gacagctcag cctatgaggt
     1561 ggagcttatc aaagagctgg aagaaaacct tgaaatgcct gttgaggtga ctattgcctc
     1621 aggctttccc aagggtgata agctagatgt tatcactcaa aaggcgactg agttaggggc
     1681 agcagctatt tggggctttc cagcagactg gtcggtggtc aagtgggata gcaagaagct
     1741 agctaaaaag caagaaaaat tagctaaaat tgctcttgga gcagcagagc aatccaagcg
     1801 taatcgcgta ccggagattc aactatttga ccaaaagggt gagctattaa agcagcttaa
     1861 gcagtttgat aagtgcttta tcgcttatga ggaagcagct aaggcaggtg aaaggtcgac
     1921 attggcgcgt gagctagcag gtcttagccc aggtcaaaaa gtcctcttta tctttggacc
     1981 agagggtggt atttcttcaa aagagctggc tagctttaag caagcaggtg ctattactgt
     2041 gggactgggg cctcgtatca tgcggacaga aacagcaccg ctctatgcct tgagtgctgt
     2101 tagctatgct ctggagctaa tgtctagctg atagtgctaa taggagacag caccttgtgg
     2161 ctcagtgctt gacagaaaaa agaggagcat ctgcgattat gctaataaag caccgcttaa
     2221 caaaaagatc gctaagaagg agactgccgc aaatcaaagg gctagtctag cccgcgtagg
     2281 tgcagagctg tcgggccttt gcagcttcat ttgtaaaaaa tataacaaat catctcaaaa
     2341 taaagatact cgtcaaacgg attggtagag gagggacatg tggttacgat aaaagatgtg
     2401 gcaaggctag caggagtttc gccttcaaca gcttcgcgtg ccatcaatga cagtgacatg
     2461 attagtcagg cgacaaagga gcgtgtcaaa aaagccatgg aggccttgga ttattcgcct
     2521 aattattcgg cgcaaaacct tgttaagcga aagtccaata ctgtcgggat cattttgccg
     2581 gtgcgtgagg gtcaggattc actgggaaat aacccttttt tcatgcagat tattcaagga
     2641 attgctgctg tttgtaccga tcagggctac atggtagccc ttgcgactgg acgtagtgag
     2701 gccgaattgc taaaaaacgt gcaaaacatg atccgtagtg gcaatattgg caagctgatt
     2761 tttctttatt ccaaaacaga tgatcaggtt tttgactttg tcaaaaggca aagagtggat
     2821 tgtgttgtcg ttgggcaatc aacgacaaag gatcctggca atgctaaatt tgtcaacaac
     2881 aataaccatc aagccggcta tgatgcagca gcatttctcc ttcaaaaagg ctatgaggct
     2941 attgtctatg cttatactga catggccgaa ttggtgcagg cagagcgtta taagggctat
     3001 gcagagctga tgacttcaaa ggctctggca gctcaagccc tttgtgtcac gctaaaggac
     3061 gataggaaaa gtcaaaagca gctgttagac caattagcca agcgctctaa agttgccttt
     3121 gtagtctgtg atgatgtgct agctattcat ttgcagcgtc tcatcaagca agtagcagct
     3181 gacacccagc tagcaatcgt tagcttcaat aattctgtcc tagcggagct tgcgagtcct
     3241 gccttgacct ccattgctat ttttccctat cagctgggag agcaagctgc tgagctggtc
     3301 ttatcaagcg cagcgccatc accacagcca gtcttagttc ctcatcagat cattgaaaga
     3361 gagtctacgc cttttattgt ttgatttacc gttaagccta ttcctaagca aagtactgat
     3421 agcttgctta ggaataaggc tttttattta ggaatttatt ttgtttgcta atagtattaa
     3481 agagaagcaa cgtttacttt agcattttca ttgaaatctt cttaagaaaa cgctttacaa
     3541 aacaaaaaaa ggttggtaaa ataagcttat caaaagcgca aacgtttgcg ttgaatgtgc
     3601 ttgtttttaa aaaggaattg agagttcatc agcttttagc tggttattct tgattcctag
     3661 tccaaaaaag gagaggtcga atgaaaacat cattcaaaca attttttagc ttcgagtttt
     3721 ggcaaaaatt cgggaaatgc ttgatggttg tcattgctgt tatgcctgct gcaggtttaa
     3781 tggtgagtat tggaaattct ctgcccatgc ttaatcagga gtcgcagctt ttagcgacgc
     3841 ttggtaatgt cattgctcag gttggttggg cagttattgg taaccttcat ttgctttttg
     3901 cccttgctat tggtggcagc tgggctaagg agcgtgctgg cggtgccttt gcttcagggc
     3961 ttgcttttgt tttgattaac cgtattacag gggctatcta tggcgtttct tcagccatgc
     4021 tgactgatcc agaggccaag attaaaagtc ttttgggcac tgagatgatt gtcaaggact
     4081 actttacaag cgtcttagag tcacctgctc taaataccgg tgtctttgtt gggattatcg
     4141 ctggctttgt gggtgcaaca gcctataaca aatactacaa ttaccgtaag ctgcctgatg
     4201 tgctggcttt ctttaatggg aaacgctttg ttccttttgt agttatcctt cgttcagctc
     4261 ttgtggccct agtattagcc ttgatttggc cagttattca gtctggtatt aatggctttg
     4321 gcatgtggat tgcctcatct caggacacag ctccaatcct tgcgccattc ttatatggaa
     4381 cattggagcg tctcttgctg ccatttggcc ttcaccacat gctaacgatt ccgatgaact
     4441 atacagctct tgggggcacc tatgaggtca tgacaggagc agctgctgga actaaggtat
     4501 ttggtcaaga ccctctttgg ctagcctggg ttactgacct tgttaatctc aagggctcta
     4561 atgcgtcaac ctatcagcat ttgatggaga ctgttgttcc ggctcgtttt aaggttgggc
     4621 aaatgattgg tgcaacagga acgcttatgg gggttgccct agcaatgtac cgtaatgttg
     4681 atgcggacaa aaagcataaa tacaaaatga tgtttatctc agcagcggca gcggtatttt
     4741 tgacaggggt cactgagcca ctggaataca tgtttatgtt tgctgcgatg ccattatatc
     4801 ttgtctatgc ccttgttcaa ggagcttcct ttgcaatggc tgatttggtc aaccttcgtg
     4861 tgcattcctt tggtaatatc gagctattga cccgaacgcc tatggcgatt aaggctgggc
     4921 ttggtatgga tttgattaat tttgtctggg tgtctattct gtttgctgtg atcatgtatg
     4981 tcattgctga ctttatgatt aaaaaaatga agctagcaac agcaggtcgc ctagggaatt
     5041 acgatgctga tatactagaa aacgatgata caaagccttt gtcacagcag tctattgatg
     5101 gtcagtcaca ggtcgtccaa atcattaatc tcctgggtgg acgtgagaat attgctgatg
     5161 tagatgcttg tatgactcgc ttgcgtgtaa cagtcaatga cccaagcaag gttggcagtg
     5221 aggagcattg gaagcaggcg ggtgctatgg ggctaatcat caagggcagt ggtattcagg
     5281 ctgtctatgg gccaaaggct gatattttaa aatcagatat ccaagacctg ctagactctg
     5341 gtgcagtcat tccagagccg aagcctgctc agcctgctgc ctcatcatca cagcagacgg
     5401 actttaaaaa cctaacagag gctgttttgg cagtagcaga tggagaagtc ttgccaatca
     5461 cagcagtttc tgatcaggtc tttgcagcta aaatgatggg agatggcttt gctgttgagc
     5521 cggcaaatgg cgctatctat gcgccggtaa caggtctggt aacccatgtc tttccaacca
     5581 aacatgcctt tggcttgctg acagatagcg gcctagaggt gctggttcac gttggtcttg
     5641 ataccgttga cttgaatggt gagcccttca ctgtcaaggt tagtgagggt cagcgcgtat
     5701 cggcaggaga tctcttggct gaggctgacc taactgcgat tacagcagca ggacgcaaga
     5761 caacggttgt tgtcgccttt accaatacta caagcatcaa agctgttaac cttgttgcga
     5821 ctggtcaaca aaaagcgaag accctcgttg cacaggtaga gctttaagaa taaccaaaga
     5881 gagtggtaga tagcagtatg tcagacctgc aggctgccac ttctcttgtc gtataggaga
     5941 agatatgacc aagctcttaa cccttaacac acattcttgg atggaagcca atgccttaaa
     6001 aaagctgttc gacttggcag agcatatttt ggctcagaac tatgacgtga tttgcctaca
     6061 agaaatcaat cagctgattg acagcgaagc agcagtgcca ttatcaggct accagccaat
     6121 tgcagggaca cctgccattc atcaggataa ctttgccctc ttgcttgtca attacttaaa
     6181 aaaacgtggc caaagctact actggtcgtg ggcctacaat catattggct atgatattta
     6241 ccatgagggt gttgcgatct tatccaagca gccgatccaa gcctcagaca ttttagtctc
     6301 agcggtggct gacgagtatg attaccacac cagacgggct ttactggcca aaacaaccat
     6361 tgatggcagg gaggcagcag ttgtgagcct gcatttgtct tggtttgatc agggctttgt
     6421 cggagaatgg cagcgattag aggcagccct gcagcagcta gcctgtcctg tgctattgct
     6481 gggagatttt aacaatccaa gtggccaaga gggctatgag atgattctaa aaagcccctt
     6541 agaccttcag gatagtcatc aggctgcaga ctacgtcttt ggagaccata gtattgttgc
     6601 tgctattgat ggctgggagg ataacaaaga ggcctttaag gtcgaccatg tctttaccag
     6661 taaggtcttt accattaaca gctcaaaggt gacctttgat ggtggtgaag caccggttgt
     6721 cagcgaccat tatggcctag aggttgacct cagctggaag ctgtaacaaa aaaagccagc
     6781 aggacttgat agactgctga cactgtaaga aacagatggt tatcttagct cttagaagta
     6841 agcttatcgc aaggcttcta agagcttttt tgcatttata tttcatgagc atatgagaaa
     6901 gttgcagaca aatgctggac acataatcag actgtgggct agttacatcg tctgctctga
     6961 tttgtgtcag atagtgatga tctgtgctgc cttgtgattg gccagatatt tacctcatat
     7021 caatagcaga aagtcaagtc tccctcagcc tatctcctag cttacgattg ctgatcatca
     7081 gtcagtctag ctacaattac ctgtgccaag cgctcaatat cagcactggt cccgcgtagt
     7141 tcgaaatctc ccagcattgg aaagccaaag cgcttagcat actgcttggc tgttagacaa
     7201 tactggtgat tgaagttttt gttgccagag ccgataatcc ctaaacaacg cttggcatta
     7261 tcatgcgccg cgataaagtc tcccagcgga ttggtcaaga tttcaacctc ccctgagtca
     7321 atcccgtttc ctccttcaag ataggtcggc aaaatagcaa caaagctctc cttgactgga
     7381 aaggtttcgt gatgaagctc cttgatattg attgctttag tctgtatgtg gtgcttttct
     7441 gccaggtatt gcgacaagcg cctaacaaag ctcagggtat tgccgctaag actgataaaa
     7501 acaagggtca agtctgtcat aaaagactcc tttagcaaga ttagtttcct aaccagctta
     7561 gcacaatacc cctgaataca caactcatat gacaatgctc tgcacgacaa acgcgcgaaa
     7621 cagtcatttc cgaatgatag tatagactta agcagataca ttcaccgttt tttctatagt
     7681 aaaagctata gaaaataaga tatcttcttg aaatagctaa acattgacat acagaaagct
     7741 ttgttttctt gctaaaaccc tatcatgcgt ctgccgtgca atgctctgac agctagccca
     7801 ctagtcacat cacataaaaa aggcttggtg acaaggacgg taagtccaaa tcatcaagtc
     7861 tttttatgga gagagcttag tgttagctgt tacccgaatc aagaggccct tgctgctaat
     7921 gcttgcgatt ttgataggtc tttgggcttt ctccggtatg ctttttgaaa aatttagaaa
     7981 aatgtgaggg atcagtgaag cccaacacgt ctgaaatgtg attaatggca taagcagagc
     8041 gcagcaatgt cttagcctct tcaattttca tgtttgaggt gtattggtag atggtcaagc
     8101 ctgtatcacg cttaaagatc tgtctcagct tggactcgct catgttaaaa tgctgtgcca
     8161 gctcagcggt tgtgacactc ttatgcaggt tgacactgat atattggata atggcattaa
     8221 ccgtaggaga gacatgtttc cagcggttgt cccgcagctc actcaccttt tgggtgtaaa
     8281 agaccagtga ggcatcacga attttgagca catctggcat tgaggttgcc agctcgctgt
     8341 ctctcatgaa ctcctctcgt gaatggtagg catcagcaat atccatacca gattgaatgg
     8401 caatctgggc tagtcgatca aaggcaatga tagaataatt tttttcagag cgcagcgtat
     8461 caccactcac cacagggata aaggtatttc gtagactgaa gatgatttcc ttgagcttgt
     8521 gcacatcacc ctcttgaaca atgctagata aatttttctc ataattgtag agacaaacct
     8581 tagattcctg cttcttgaca aacatattgg ccttttgcac ctcgatattg tcggaaaaat
     8641 ccctaatata gtgacgtaaa ggaggtgata acaaatcctc tatcttgccg gaaaagaagt
     8701 aatggaccac aatcaagagg tcacgaatag cattcaaagg ataaacaggt aaatgcttta
     8761 gcgcttggta aagaatctct tcttcttcct tagtcaaatc cttatcagca acggccacct
     8821 taaaaaaggt cttatccaaa acattacagc gccaagggcc aattaaaata taatgatcct
     8881 gataacggta tattaaaaaa agctcattat agcttccctg aaagaaaaga ttggttgcct
     8941 gttccttgtc catttgccta agcactgctt gaaaacgata ataaaattca aaggtatcat
     9001 cattccaaaa gctttctgtc acctgatggt ccttatcaaa tactgtaatt gataacttca
     9061 aacagccctg tagagatttt actaacgaca tagtatccat gctaagcgtc acccccttca
     9121 taatcctcac ggtatcttat tctatcttaa aatttaa
//
LOCUS       DARYXW010000077         9136 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.077, whole genome shotgun sequence.
ACCESSION   DARYXW010000077 DARYXW010000000
VERSION     DARYXW010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9136
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.077"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(380..2554)
                     /gene="nrdE"
                     /locus_tag="TV191_001528"
     CDS             complement(380..2554)
                     /gene="nrdE"
                     /locus_tag="TV191_001528"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEL1508026.1"
                     /translation="MSQKESYLSLNALTRFKRADGTYHFDSDKEAVQRYLEEHVYPQS
                     LSFDSLEEKWRYLVAHDYYDQEILKAYSAECITEAFTYAYQQKFSFLSLMGAMKFYQS
                     YALKTLDGSQYLEHFEDRAVMNALFLANGDPDLVRDLIDQILSGRFQPATPTFLNAGK
                     KRRGEYISCYLLRIEDNMESISRAIGTSLQLSKRGGGVALCLTNLREVGSPIKGIENQ
                     ATGIVPVMKLLEDSFSYANQLGQRQGAGAVYLNVHHPEILTFLDTKRENADEKIRIKS
                     LALGVVIPDITFQLARENKDMALFSPYDIKRVYGKDMSDIAITEEYDRLVANPAIKKT
                     YISARKLFQLIAELHFESGYPYLLFDDTVNKRNPHPQKGRIVMSNLCSEIAQVSTAST
                     FEEDLTFKQIGEDICCNLGSINIAEAMKHAVGFEQLIATSVRALDHVSRASDVSCAPS
                     VEKGNAANHAVGLGAMNLHGFLATNHIFYDSAEAVDFTDLFFHTMAYYAFKASSQLAK
                     EKGAFAGFEQSTYADGSYFARYLTKEAKPKTAKVAALLERYGLRVPSVADWQELVATI
                     QETGLANAHLMAVAPTGSISYLSSCTPSLQPVVAPVEVRKEGHLGRIYVPAYQISDDN
                     YAYYERGAYEVGPEPIINIVAAAQKHVDQAISLTLFMTDQATTRDLNRAYIHAFKLKC
                     ASIYYVRVRQDVLEGSEQYEEDTIVALTDTNASGEACQSCML"
     gene            complement(2601..3008)
                     /gene="nrdI"
                     /locus_tag="TV191_001529"
     CDS             complement(2601..3008)
                     /gene="nrdI"
                     /locus_tag="TV191_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEL1508027.1"
                     /translation="MAARVMLVYFSSRSNNTHRFVQKLDVRALRIPVTGEPLLVDEDY
                     ILIVPTYAAGGSDSKGAVPKQVIHFLNKANNRRHCKGVISSGNTNFGDTFAIAGPIIA
                     QKLQVPLLHQFELLGTQRDVIKVQAILAGDEAL"
     gene            complement(3010..4023)
                     /gene="nrdF"
                     /locus_tag="TV191_001530"
     CDS             complement(3010..4023)
                     /gene="nrdF"
                     /locus_tag="TV191_001530"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEL1508028.1"
                     /translation="MTQYYYDRSQSPIDYALSQTKKSLRSVNWNQLNDDKDLEVWNRV
                     TQNFWLPEKVPVSNDLNSWRSLGEDWQRLITRTYTGLTLLDTVQATVGDVAQIQHSLT
                     DHEQVIYTNFAFMVAIHARSYGTIFSTLCSSQQIEEAHDWVVSTESLQERARVLIPYY
                     TGDDPLKSKVAAAMMPGFLLYGGFYLPFYLSARGKMPNTSDIIRLILRDKVIHNYYSG
                     YKYQQKVAALSPEKQAEMKAFVFDLLYQLIDLEKAYLRELYDGFDLADDAIRFSVYNA
                     GKFLQNLGYDSPFTEEETRISPEVFAQLSARADENHDFFSGNGSSYVMGVTEETIDDD
                     WEF"
     gene            complement(4704..6707)
                     /gene="metG"
                     /locus_tag="TV191_001531"
     CDS             complement(4704..6707)
                     /gene="metG"
                     /locus_tag="TV191_001531"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003006062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEL1508029.1"
                     /translation="MTKKKPFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRMLGYD
                     VFYLTGLDEHGQKIQDKAQEAGLSPQAYVDGMAEEVKALWKLLDISYDKFIRTTGDYH
                     EEVVAAVFERLLAQDDIYLGTYSGWYSVSDEEFFTESQLAEVYRDEAGKVIGGVAPSG
                     HEVEWVSEESYFLRLSKYADRLVAFFKAQPDFIQPDGRMNEMLKNFIEPGLEDLAVSR
                     TTFTWGVPVPSNPKHVVYVWIDALLNYATALGYGQKDHANFDKFWSGRVFHMVGKDIL
                     RFHSIYWPILLMMLDLPMPERLIAHGWFVMKDGKMSKSKGNVIYPEMLVERFGLDPLR
                     YYLMRSLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVAMINKYFDGRVPAYVRNV
                     TAFDADLEQVVADHISEYHKQMEAVDYPRALEAVWTIISRTNKYIDETAPWVLAKAAD
                     SKEQLASVMAHLAASLRVVAHLIQPFMMTTSAAIMEQLGLGAKYHLEELDLADLPTGV
                     TVVAKGEPIFPRLDMEAEIDYIKEQMTMSIAKPQEADWDPEKVALKSEKDTITFEAFD
                     AVEIRVAEVKEVSRVEGSEKLLRFRLDAGDGSDRQILSGIAAYYPNEQELVGKKVQIV
                     ANLKPRKMMKKYISQGMLLSAEHDGKLTVLTVDPAVPNGTIIG"
     gene            complement(6925..7623)
                     /locus_tag="TV191_001532"
     CDS             complement(6925..7623)
                     /locus_tag="TV191_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEL1508030.1"
                     /translation="MSKRKRKTYQVYEGLRCAMMLCFISGYVNAFTYMTQGRRFAGVQ
                     TGNLLSFAIRLSERQFDQALQFLLPIIVFMIGQAFTYFMHCWANKHGLHWYLLSSFIL
                     TLIALVTAILTPLLSSFFTVSALAFFASIQVDTFKTLRGASYANVMMTGNIKNAAYLL
                     TKGLYENNKELVHIGRNTLIIILSFALGVVCSTLLSLSYGEYALSPMLIPLCYVNYLL
                     AQEFYHHQVSLKND"
     gene            complement(8009..9030)
                     /locus_tag="TV191_001533"
                     /pseudo
     CDS             complement(8009..9030)
                     /locus_tag="TV191_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515161.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
BASE COUNT         2694 a         2159 c         1785 g         2498 t
ORIGIN      
        1 aatattttag aaatactata ggttattttg aatcttctga ttgttttgac agttacaaga
       61 aatcccagtg attaacacgg agacaagccc cagtaattat cgattgaaga gggagctttt
      121 ttcttgattc tccttaagca aatcagcaag cattggctta tccaagccaa atgtccttac
      181 aacaagcacc ggtagcccac ttcatttgac aaggggcttg tcagcaagca ttgatcacaa
      241 atcaggctga gctgcattaa gctcaagaga gcttgccatc agcctgttgg atcaagcgat
      301 actataagcc tattaacaaa ctggctagac agagcatgaa ggctgattgg tgctgcctat
      361 ttttaaggct aaaaaagatc taaagcatgc aggattggca tgcctcgcct gaagcattgg
      421 tatcggtaag cgctacaatc gtatcttcct catactgctc acttccttcc agaacgtcct
      481 gtctgacgcg aacataataa atggacgcac actttaactt aaaggcgtgt atataggcac
      541 ggttgagatc acgtgttgtt gcttggtctg tcataaatag ggttaaggaa attgcctgat
      601 caacgtgctt ttgagccgct gctacgatat taataatagg ctcaggccca acctcatagg
      661 caccacgctc gtaataagca tagttatcat cgcttatctg ataagcaggc acataaatcc
      721 ttcctaagtg cccctccttt cgcacctcaa ctggtgcaac aacaggctgt aagctcggcg
      781 tacatgagga caagtagctg atcgagccgg ttggtgcaac tgccatcaag tgagcattgg
      841 caaggcctgt ctcttgaatc gtcgcaacta attcctgcca atcagccaca ctaggcactc
      901 gaagcccgta gcgctcaagc aaggccgcaa ccttagctgt cttaggctta gcctcttttg
      961 tcaaatagcg ggcaaagtag ctgccatctg cataggttga ctgctcaaag ccagcaaatg
     1021 ctcccttttc cttagctaat tgactagaag ccttaaaggc ataataggcc attgtgtgga
     1081 aaaagagatc agtaaaatct actgcttcag ctgaatcata aaagatgtga ttggtcgcca
     1141 aaaagccatg taaattcatc gcgccaagac caacagcatg attagcagca ttcccctttt
     1201 caacagaagg agcgcagctg acgtctgagg cccttgacac atggtccaag gccctaacac
     1261 tagttgcaat caattgctca aagccaaccg catgcttcat ggcttcagca atattaatag
     1321 agccaaggtt acagcaaatg tcctcgccga tttgcttaaa ggtcaaatcc tcttcaaagg
     1381 tgcttgctgt gctgacctga gcgatttcag agcaaaggtt tgacatgaca atccgcccct
     1441 tttgtgggtg tggattgcgc ttattaaccg tatcatcaaa caagagataa gggtagccag
     1501 attcaaaatg aagctctgca ataagctgaa agagcttacg ggcactgata taggtctttt
     1561 taatggctgg gttggccact aggcggtcat actcctcggt aatggcaata tctgacatgt
     1621 ccttgccata aactcgctta atgtcatagg gagaaaatag cgccatgtcc ttattttccc
     1681 gcgccagctg aaaggtaata tcaggaatga caacgcctaa cgccagtgac ttgatacgga
     1741 ttttttcgtc tgcattttct ctcttcgtat ctaaaaaggt cagaatctct gggtgatgca
     1801 cattgaggta aaccgcacct gctccctgtc tttgccctag ctgattggca taggaaaagg
     1861 aatcctccag tagcttcatc actggcacaa tgcctgtcgc ttgattttca atgcctttta
     1921 tgggagagcc aacctctctt agattggtta aacacaaagc aacgccgccg cctcgttttg
     1981 agagctgcaa gctcgtacca atcgcacgcg aaatagattc catgttgtct tcgattcgca
     2041 gcaaataaca ggaaatatat tcgcctcgac gctttttacc tgcatttaaa aaggtagggg
     2101 tcgccggttg aaagcgcccg ctaagtatct gatcaatcaa atcccgcacc aaatcaggat
     2161 caccattagc caaaaacaag gcattcataa cagcacgatc ctcaaaatgc tctaggtatt
     2221 gtgacccatc tagggtttta agcgcatagg actggtaaaa tttcatggct cccattaagc
     2281 tcaaaaatga gaacttttgc tggtaagcgt aggtaaaggc ttcagtgata cattcagccg
     2341 aataagcctt taaaatctct tgatcataat aatcatgcgc caccaaataa cgccatttct
     2401 cctccaaact atcaaaggat aggctttgtg ggtagacatg ctcctctaaa tagcgctgaa
     2461 cagcttcctt atcactgtca aagtgatagg taccatctgc tcgtttaaag cgtgtaaggg
     2521 catttaatga gaggtaggac tctttttgtg acattctttt ttcctttcgt tacaatgtgt
     2581 gatcgttttt ctatcattag ttataaggct tcatcacctg ctaaaatagc ctgcaccttg
     2641 atgacatctc tttgtgtccc cagcaattca aattggtgca aaagcggcac ctgcaatttt
     2701 tgtgcaatga ttggtcctgc aatggcaaag gtatcaccaa agttagtatt gccagaggaa
     2761 ataaccccct tacagtgcct tcgattgtta gccttgttta gaaaatgaat cacctgcttg
     2821 ggaacagctc ccttgctgtc tgagccacca gcagcatagg tagggacaat caaaatataa
     2881 tcctcatcaa ctaatagagg ctcaccagtg actggaattc ttagagctct tacatctagc
     2941 ttttgcacaa agcggtgagt gttgttagat cgcgatgaaa aataaacaag cattaccctt
     3001 gcagccatct taaaactccc aatcatcatc aatggtttcc tcagtaactc ccatcacgta
     3061 agaagagcca tttcctgaga aaaagtcatg gttctcatct gctcgcgctg atagctgagc
     3121 aaatacctca ggggaaatac gtgtttcctc ctcagtaaag ggagaatcat accctagatt
     3181 ttgcaaaaat tttccagcat tatagacgct aaagcgaatc gcatcgtcag caagatcaaa
     3241 gccgtcatac aattccctca ggtaagcctt ctccaaatca atcagctgat aaagcagatc
     3301 aaacacaaag gccttcatct cagcctgctt ttcaggactt agggctgcca ccttttgttg
     3361 atacttgtag ccactgtaat aattgtgaat gaccttatct ctcaggatta agcgaataat
     3421 atctgaggta ttgggcattt tgcctctagc tgacaggtaa aaaggcaggt aaaagccacc
     3481 atatagcaaa aatcctggca tcatagctgc tgcgacctta gacttcagag ggtcatcacc
     3541 agtataatac ggaatcaaca cacgcgctcg ctcctgtaag ctctctgttg acaccaccca
     3601 atcgtgggcc tcctcgatct gctgactgct gcacagggtc gaaaagattg tcccatagga
     3661 cctagcgtga atagcaacca taaaggcaaa attagtataa atcacctgct catgatcggt
     3721 caaagaatgt tgaatttgtg ccacatctcc aactgttgct tgaaccgtat ctagcaaggt
     3781 caagccggta taggttcttg tgatgagcct ttgccaatcc tcccccaaag aacgccaaga
     3841 attaaggtca ttagaaacag gaaccttctc aggcagccaa aaattttgcg tcacacggtt
     3901 ccagacctcc aggtccttgt cgtcattaag ctgattccaa ttgacagagc gcaaactttt
     3961 tttggtttga gacaaggcat agtcaatggg tgactgtgat cggtcgtaat aatattgggt
     4021 catgttttct ccttcaagct tgatagtcgc aatatcaatc cttcagctgc caagccttct
     4081 acagctttag gactagggaa gactgctaag tgccacattt agacaacaca aaaagacttg
     4141 ctctaaaggg caatcctaca ggctaatgat aatttcttgc tgatgatccc taaccagtca
     4201 gcaactgctt tgtaagcaag gctaagcccg cttttttccc cggctgaatt aagtatactt
     4261 aattcttatg tttgttataa taacacaata tatagtgctt tgcaatcttt ttgatacaat
     4321 atatagatta atttatgaaa aagaaatcat aaaaggagct agcagcacct taacgaaagc
     4381 cctgtctgta tgctcaccaa tccctcatct gccaacttgc ttttcaaata agatcaatac
     4441 atatcaattc acacccccat gaagggagcg actagagcgt gagataaaga aacaaaaatg
     4501 atgtattttc aatactcaga gctttcactg ctgttattgc ctattaggct gctagactag
     4561 tgcttctttc ttgttcaaag tttacaaagc tcccacaaga agtctaggtc tcttgtcttt
     4621 ttaagacact aaaaatcccg tatgctcctg ctaatcaatc tattagcaag acccatacgg
     4681 gatattgtca tctaaaagcc caatcagcca ataatcgtac catttggcac tgccggatca
     4741 accgtcagca ctgtcagctt gccatcatgt tctgctgaca aaagcatgcc ctgactgata
     4801 tattttttca tcatttttcg cggcttgagg ttggcaacaa tttgcacctt cttgccaacg
     4861 agctcttgtt catttgggta ataggctgca atacctgata agatttgacg atcagagcca
     4921 tcacctgcat ctaatctaaa gcgcagcagt ttttcagagc cttcaactcg tgacacctct
     4981 ttgacctctg ccacacgaat ctcaactgca tcaaaagcct caaaagtaat cgtgtccttt
     5041 tcagacttaa gggctacctt ttcaggatcc cagtctgctt cttgtggctt agctatgctc
     5101 attgtcattt gctctttgat atagtcaatc tctgcttcca tatcaagacg agggaagatt
     5161 ggctctcctt tggcaacaac cgtcacacct gtcggaagat ctgctaaatc aagctcttcc
     5221 agatgatatt tggcaccgag acctagctgc tccataatag cagctgaggt tgtcatcata
     5281 aatggctgaa tcaaatgagc caccacgcgc agacttgcag ctaaatgtgc catcacactg
     5341 gctagctgct ccttactatc agctgctttg gcaagcaccc aaggagcagt ttcatcaatg
     5401 tatttgttcg tgcgtgaaat aatcgtccat acggcctcca aggcacgtgg gtaatcaaca
     5461 gcctccattt gcttgtggta ttcggaaata tgatcagcca caacctgctc cagatccgca
     5521 tcaaaagctg taacgtttct gacataagca ggaaccctgc cgtcaaagta tttattaatc
     5581 atggcaactg tacgattcaa aaggttacca aggtcattag ccagctcata attgatacga
     5641 ccaacataat cctctggggt aaaggtacca tcagagccaa ccggcaagga acgcatgagg
     5701 taataacgca gaggatcaag accaaagcgc tcaaccagca tttcaggata gatcacattc
     5761 ccctttgatt tagacatttt accgtccttc atgacaaacc agccatgagc aatcaaacgc
     5821 tctggcattg gtaaatcaag catcatcaac aaaattggcc aataaatgct gtggaaacgc
     5881 aaaatatcct taccaaccat atggaaaacc ctaccactcc agaacttatc gaagttagca
     5941 tgatccttct gaccgtagcc tagtgctgtt gcatagttta agagagcatc gatccagaca
     6001 taaacaacgt gtttaggatt tgacggcaca gggacccccc aggtaaaggt tgttcggcta
     6061 accgctagat cctccagacc tggctcgatg aagtttttaa gcatttcatt catacgaccg
     6121 tccggctgaa taaaatcagg ctgagcctta aagaaggcaa ccaatctatc cgcatacttg
     6181 ctcaggcgca aaaaataaga ttcttcagag acccattcga cctcatgccc tgatggtgcc
     6241 acaccaccaa tgaccttgcc agcttcatcg cgataaacct cagctaactg actttctgta
     6301 aaaaattcct catctgaaac agaataccag cctgaatagg tccctaaata aatatcatcc
     6361 tgcgccagca acctctcaaa tacagcagca accacctcct catgatagtc gccagtggtg
     6421 cggataaact tatcataaga gatatcaagg agcttccata gtgccttgac ttcctcagcc
     6481 atgccatcaa cataagcttg aggggataag ccggcttctt gtgccttatc ctgaatcttt
     6541 tgaccatgct catcaagacc agtcaaataa aaaacgtcat aacccaacat acgcttatag
     6601 cgagcaagaa catcacaggc aatcgtagta taggcagagc caatatgaag cttccctgac
     6661 gggtagtaaa tcggtgttgt aatataaaat ggttttttct tagtcatctt acgtcctttc
     6721 aaggctaatg aaacctttgt aatcagggac tagggcaata cccattccca agctgagtcc
     6781 tgtcagctat caactgacat tataccataa ttttagcata aaaaaatgat cactcagcct
     6841 attaactgat acctccccca taatagacaa tgacaaacaa gcagtcatca aaaattatag
     6901 gaggaggata tcaattagta gacttcaatc atttttcaat gatacctgat gatggtaaaa
     6961 ttcctgtgcc aagaggtagt tcacgtagca caatgggatc agcatgggag ataaggcata
     7021 ctcaccatag gatagtgata aaagagtaga acagaccact ccaagggcaa aggagaggat
     7081 aataatcaag gtattgcgac caatatggac tagctctttg ttgttctcat atagtccctt
     7141 tgtcaatagg taggcagcat ttttaatatt accagtcatc atcacattgg catagctcgc
     7201 accgcgcaag gttttaaagg tatctacctg aatcgaagca aaaaaagcta gagctgaaac
     7261 cgtaaaaaat gacgacaata agggtgtgag gattgctgtc acaagagcaa tcagggtcaa
     7321 gataaagcta gacaaaaggt accaatgcag accatgctta ttggcccagc agtgcataaa
     7381 gtaggtaaag gcctgcccaa tcataaaaac aatgataggc aataaaaatt gcagggcttg
     7441 gtcaaactgg cgctcagaca gacgaatcgc aaaggataag agattgcctg tctgaacccc
     7501 tgcaaagcgc ctgccttgcg tcatgtaggt aaaggcattg acataaccac tgataaagca
     7561 aagcatcatg gcgcacctta agccctcata tacctgatac gtttttcgtt tcctctttga
     7621 catacttgcc ttccttaatg tgattccaaa agaaaaatac tgacaaacag tatttgatgt
     7681 gattattagg aggataagct aagctcaatt gcccttgatc acagatagtc accaaagcaa
     7741 gttctgcagc tagactcggt aagtccccca aatacagctt tagtatagca taggcagtct
     7801 cttttatcaa gatgctttgc aggatcaact agcaccataa gactaaccat tagccaaaaa
     7861 gtactcaccc tctatgagga ccagcaggta aacctgataa aaaaactaaa aagccaccat
     7921 ttctgatgac ttcttagtcg gcctcttcaa caacttgtag cttacacaag ctatagcgct
     7981 aaggacagcc tttcattgga gcacaacatt agtcttcctt gcgttttgtt gacacaacaa
     8041 ccacacctgc acttgccatc actgcaagag ctgccgctgt gaagaatgga tgtgtcgctt
     8101 cacctgttga tggaagcttc ttagcttctt gcttaggtgc tggtttcttc tcttccttct
     8161 tagcttcagg ttttggttct ggcttaggct caggttttgg ttctggttta ggctcaggtt
     8221 taacctcttc atacacataa accacacgaa gatcgccttc tagggttgta ccagtttcgc
     8281 taggtgagcc ctcttgaagc ttcttgaact tgtagacctt accatctttt tcaatcttat
     8341 caagacgaag tgaggtagta tcgtacgctt cacccggcaa gccttgtgat accgcaacag
     8401 tttcacctaa aacattacct tctgtatcca cataagatac aagaacatta gcattaaacg
     8461 gaacaaattc ccaatcacca attaaagtaa tatctccatc acctggtgct gtatagccct
     8521 ctgtaagttt agtttcacca tcatttgtgt aacgtgacca accagtaaat ctccactcac
     8581 cagttgcagt tctgacattt tagcaacatc aagaagctcc tgtggtaaag tcataccttg
     8641 cttgctaccg aaaatgtaga taactgtact cttctcttta cgaagagctt cattagctgc
     8701 ttcttcttcg gcacgttttg atctttctgc ttctgcctta accgctatag tttgttcagc
     8761 ctcagctaag attttgttaa tatcgtcaac ttgaattaaa tttgaatcgt taattttcga
     8821 ttcaaaacct gcgattgttg aagccaattc cggatgctgt tgtttaagag tagttagacg
     8881 agctgtagcc tcagctttag ttgcatactt ctgccctctc attgttacct gtgccgatac
     8941 agaagctgta ccaactaaca aggtgcagaa tactgaagct agtccgaaag ccgacttacg
     9001 aagatagtac ttcatttctt tttttgccat ttttattccc ctttaaatat aatggacata
     9061 atgtctccta attatcaatg acagataatt acacttttat tataaaaggt attttctgtt
     9121 tagtcaagag aaaact
//
LOCUS       DARYXW010000078         9038 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.078, whole genome shotgun sequence.
ACCESSION   DARYXW010000078 DARYXW010000000
VERSION     DARYXW010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9038)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9038)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9038
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.078"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            39..284
                     /locus_tag="TV191_001534"
     CDS             39..284
                     /locus_tag="TV191_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEL1508031.1"
                     /translation="MGIIWTLIVGALIGAIAGALTKKGGSMGWIANIAAGLIGSYVGQ
                     ALFGSWGLTLAGMALFPSIIGAVIVVIITSFVLNKSN"
     gene            332..913
                     /gene="amaP"
                     /locus_tag="TV191_001535"
     CDS             332..913
                     /gene="amaP"
                     /locus_tag="TV191_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEL1508032.1"
                     /translation="MSKFLKISYSLIGLVLLTVFGGVIAITGDYIRLPIGYQWLHWDM
                     NWLPKFLNPALYYYYFWAAIALFLITVLILLVIIFYPRTYTEIQLAKDKGTLLLKGSA
                     IEGYVAAAIKAAGLMSSPRVTAKLYKRKFKVNVSGQLASRVAVTEQLNGIKEGIETGL
                     TEFFGINRPVHFKVYVKDIADAKQKHSSKRRVE"
     gene            923..1111
                     /locus_tag="TV191_001536"
     CDS             923..1111
                     /locus_tag="TV191_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEL1508033.1"
                     /translation="MAFYERFKYPIIGGLIGLIAAVLLMTFGLFKTLLAIIFIILGVY
                     GGLYAKKTGIIDQLIKRN"
     gene            1124..1663
                     /locus_tag="TV191_001537"
     CDS             1124..1663
                     /locus_tag="TV191_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL1508034.1"
                     /translation="MTETYIKNTTHKEPTSAVRGELTYDDKVIEKIVGLALENIDGLL
                     GVNGGFLANLKDKLVNSDSVRDGVNVEVGKKEVAVDLDIVAEYQKHVPTIFDAIKSVV
                     ENEVKRMTDLEVIEVNVKVVDIKTKEQFEADKVSLQDKVTEVARSTSEFTSKQVDNVK
                     ASVGAGVEKVQEQTEPRVK"
     gene            1701..1898
                     /locus_tag="TV191_001538"
     CDS             1701..1898
                     /locus_tag="TV191_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEL1508035.1"
                     /translation="MSEEKVNAKLEQAGGKIKEAFGKVTGDKSLETEGKVDQAASKIK
                     EVAADAKDAVKGFVKGLKQDK"
     gene            1908..2396
                     /locus_tag="TV191_001539"
     CDS             1908..2396
                     /locus_tag="TV191_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL1508036.1"
                     /translation="MKAKDIKSTLTYDDKVIEKIVGHALEKVSGLLAVNGGFFSNIKN
                     NLVNSDSVRDGVSVEVGSKEVAVDLDIVVEYGKDIPAIVESIKAIVFQNVDSMTHLRV
                     VEVNVNVVDIRTKEEHEAASVTVQDRLTDAASATSQFVAEQADKVKETVSKTTDNNET
                     VE"
     gene            2552..3193
                     /locus_tag="TV191_001540"
     CDS             2552..3193
                     /locus_tag="TV191_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1508037.1"
                     /translation="MTSNKREITNSKYQKIAISVAERIANGEYEVGEKLKSRTTIAST
                     FKVSPETARKGLNILADLKILTLKHGSGAIVLSKEKAIDFLNQYESTHSIAVIKENIR
                     HNIREQEKAMEHLTVLVNEFLMQSQSISKQYPLAPYEIICSQDSEHFGQSIGDLNIWH
                     QTGATIVAIEHDGQFIVSPGPYAVIEKGDHIYFVGNEDVISRMKTFFNVRKGL"
     gene            complement(3310..3858)
                     /locus_tag="TV191_001541"
     CDS             complement(3310..3858)
                     /locus_tag="TV191_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEL1508038.1"
                     /translation="MTTRHTPTKAYLKQALVSLLTEKSFETITVSDLTKKAGVNRGTF
                     YLHYRDKHDMMTHLINDTLDDLYQLLNDPHIFTDTRLVLKEALAYIIDNLPFIAAMAN
                     SSYLNFSQILKDFIYQFLTTIDGFQEIITKHYQIPYHYALEVYLASIESLISYWISHD
                     CQETTDDMTAIILKTVGFEKVI"
     gene            3981..4682
                     /locus_tag="TV191_001542"
     CDS             3981..4682
                     /locus_tag="TV191_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1508039.1"
                     /translation="MSYIEMRSSSKTYQIGETTVKANDEVSFEIERGELVIILGASGA
                     GKSTVLNILGGMDSNDQGQVIIDGKDISTYSKKALTSYRRYEVGFVFQFYNLVPNLTA
                     KENVELAADIVADALDPTTVLNEVGLGGRLEHFPAQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDYQTGKQILRLLQDMAHDKGRTVIVVTHNTALAPIADRVIYMHDGRVTK
                     TVLNKQPLDIDRITY"
     gene            4694..7333
                     /locus_tag="TV191_001543"
     CDS             4694..7333
                     /locus_tag="TV191_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEL1508040.1"
                     /translation="MKQKTLWKDSFRAIKASKGRFLSLLFLMALGSFALVGLKVAGPN
                     MEKTASHYLEEHQVMDLSILASHGFSDRDKQELASLKNARLEYASFVDGAFDHQRKAI
                     RLYSMPQSLSQASLVKGDYPSKASDILLSEALSSRYRLGQIITISLKTKGLLKHRSYR
                     VVGFAHSPEIWSKTNLGVSSAGDGNLYAYAYLHPSAFQQGHNLLRIRYDDLRGLNAFS
                     TQYNERLLQHQAELDQILQDNGQERYEEMLNDLNRSLKDSKVKLEEQRTVLKASEDQL
                     ALLSGHALEQAQTQLKQGQEELAKKEASLLELAEKQRAAMIKPTYTSYSRSTLPGGEG
                     YQTYATSTQSISHVGNIFPVVLYLVAALVTFTTMARYVDEERTNSGLLKAIGYSDWDI
                     TKKFLLYGALAALLGTGLGVLGGTYFLSRLISAILTDALTIGSTQLYFYWSYSVVAVL
                     LALLSAVLTAYMVVRRELFLRPSQLLLPKPPSSGARIWLEHVSFIWRRLSFTYKVTFR
                     NIFRYKQRMLMTVIGVAGSVALLFSGLGIQSSLANSLSYQFGKLTAYDMLVVEAPTAE
                     AHDRQELAQYLKADQIASKKEIYYANLSLKIKDLDNKQTVSLISSDQSTLSPYFSLIG
                     AADRKKLDLPSTGVLISKKLADYYQAHAGDQLELEASNGKRYQLRVSQVIDMTVGHYL
                     FMSKSYYQQVFRDMEASPSYLVTTAKASPSAVKDVASQLLAMPAVQAVSQHSSIVATV
                     TGIVASLDQVMTLLVLLSVLLALVILYHLTNINIAERVRELSTIRVLGFYDKEVTLYI
                     YRETMLLSAVGILIGLWGGSYLHAYIMKVIANDSMSFGRTVDAYVYLVPVGAIVLLLI
                     VLGYMVSYRLRKIDMLEALKSVD"
     gene            7409..8005
                     /locus_tag="TV191_001544"
     CDS             7409..8005
                     /locus_tag="TV191_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEL1508041.1"
                     /translation="MEAMIAAYLADHREKIPLGQVVDCFKGKAVSRKAEAGEFGLINL
                     SDMGQLGIDYHQVRAFHMDRRQLLRYILEDGDVLIASKGTVQKVCVFHKQEREMVASS
                     NITVLRPQRVLRGYYIKFFLESAIGQALLKAADHGKDVINLSTKALLDIPVPVIPLVK
                     QDYLINQYLRGLHDYQRKVNRAEQEWQFIQNEIQKGLG"
     gene            8015..8977
                     /locus_tag="TV191_001545"
     CDS             8015..8977
                     /locus_tag="TV191_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEL1508042.1"
                     /translation="MSLIERTIKMLLATMAAIFLASQLQLSYAISAGIIALLGVLDTR
                     KSSLIVARKRLLSFFLAFAVAVSLFALFGFGLLSIGLYLALTIPLLYQLKIEAGLVPI
                     TVLVTHLMSEQRIDLSILFNELLLFLIGTGLALLVNGYMGSQEHRLRLYHQKIEDSLK
                     AILYRFESFLLEGQGQNEGQMIKELELSLDEALKLVYRERHNTLFYHTNYQVHYFEMR
                     RHQNRLLAQMALNVTQLTSQSRESLLLSHLFHETARQLSEKNSALTLIDDIEQLLEVF
                     RQRELPQTREEFERRAILFQLLQDLERFILLKVEFYRDYKEEQA"
BASE COUNT         2605 a         1567 c         2125 g         2741 t
ORIGIN      
        1 gtgaacaaag tagttttatt gaattgagga gatttattat gggaattatt tggacattaa
       61 ttgtgggtgc acttatcggt gctattgccg gtgcgcttac taaaaaaggc ggatcaatgg
      121 gctggattgc caatatcgct gcaggactta ttggatcata cgttggtcaa gctttgtttg
      181 gcagctgggg tctaacatta gctggcatgg cacttttccc atcaatcatt ggtgctgtta
      241 tcgttgttat cattacttct tttgtactaa ataaatcaaa ctaagggcat ttctatcatt
      301 atagagatgg ttgagtagga aagaggtttt tatgtcgaaa tttttaaaaa ttagctatag
      361 tctcattggc ttagtcctat tgacggtctt tggtggcgtg atagccataa ctggagatta
      421 tattaggcta cctattggct atcaatggct tcactgggat atgaattggc ttcctaaatt
      481 cctaaatccg gccttatatt actattactt ttgggcagct atcgctttat ttctaataac
      541 agtgctgatc cttcttgtga ttatctttta tccacgcacc tatactgaga ttcagctggc
      601 taaggataaa ggaaccctgc ttttgaaagg gtctgctatt gaaggctatg tagcagctgc
      661 tattaaagca gcagggctta tgtcaagccc aagagttacc gctaagctgt acaagcgtaa
      721 atttaaggtt aatgtcagtg gacaattagc ttctcgcgta gctgtcactg agcagctaaa
      781 tggcattaaa gaaggaattg agactggttt aacagaattc tttggtatta atcgacctgt
      841 ccatttcaag gtttatgtca aggatattgc tgatgctaag caaaagcata gctctaagag
      901 acgtgtagaa taggagatta tcatggcatt ttatgaacgg tttaaatacc ctattattgg
      961 tggtctgata gggctgatag ctgctgtatt actgatgacc tttgggttat ttaaaacact
     1021 gctggcaatt attttcatta ttttaggagt atatggcggc ctgtatgcca aaaagacagg
     1081 tattatcgat caattgatca aacgtaacta aaggagattt atcatgactg aaacttacat
     1141 taaaaacaca actcataaag aaccaacttc agctgttcgt ggcgaattga cctatgatga
     1201 caaggtcatt gaaaagatcg ttggcttggc tcttgaaaac attgatggcc tactaggtgt
     1261 taatggtggc tttttggcca atctaaaaga caagcttgtt aatagtgatt ctgttcgtga
     1321 tggggttaat gttgaggttg gtaaaaaaga ggttgctgtt gatttagaca ttgtagcaga
     1381 ataccaaaag catgttccaa ccatttttga tgcgattaaa tctgtcgtag aaaatgaagt
     1441 caagagaatg acagatttag aggtgattga ggttaatgtt aaggttgttg acattaaaac
     1501 caaggagcaa tttgaagctg ataaggtcag cctacaggat aaggtgactg aggtagctcg
     1561 ctcaacctct gaatttacaa gcaagcaggt agacaatgtt aaggcatctg taggtgcagg
     1621 tgtagaaaag gttcaagagc aaactgagcc acgcgttaag taagctaggc tgtcaaacga
     1681 tagaaataga ggaaatcata atgtcagaag aaaaggtaaa tgcaaaattg gagcaagcag
     1741 gcggtaaaat caaagaagcc tttggaaagg tgactggtga taaatcctta gaaaccgaag
     1801 gtaaggttga tcaagcagcc agcaaaatca aagaagtagc tgctgatgct aaggacgctg
     1861 tcaagggctt tgttaagggc cttaagcaag ataaataagg agttgtaatg aaagcaaagg
     1921 acataaaaag tacgttgacc tacgatgata aggtcattga aaaaatcgtt ggacatgctt
     1981 tagagaaggt cagtggctta ttagcagtca atggtggctt tttctcaaat atcaaaaata
     2041 acctagtgaa tagtgactct gttcgtgatg gggtgtctgt tgaggttggc agcaaggaag
     2101 tggctgttga cttagatatt gttgttgaat atggtaagga tattccagca attgttgagt
     2161 ctatcaaggc tattgttttt caaaatgtcg atagcatgac acatttgagg gtcgttgaag
     2221 taaatgtgaa cgttgttgat attagaacca aagaagagca tgaggctgct agcgtcactg
     2281 ttcaagacag gctaacagac gcggcctcag caacctctca atttgtagct gagcaagcag
     2341 acaaggtaaa agaaactgtc tctaaaacca cagataataa cgagacagta gaataaaaca
     2401 caacaactaa aactcctgtt aatgacatat tgtgggctgg tgtgatgacc agctcttttt
     2461 atcagtgctt gaacaatgtt atgctattgt attctctgtg aaaatgtgat ttaatgggaa
     2521 tggtatcatt tgttaaaaag gagtaattat catgactagt aataagagag agattactaa
     2581 ttccaagtat caaaagattg ccatttcagt tgctgaaagg attgccaatg gcgaatatga
     2641 agtgggagaa aagctaaagt ctaggacaac cattgcttcg acctttaaag tttcgcctga
     2701 aactgctaga aagggtctga atattttagc tgatctgaag attttgacct taaagcatgg
     2761 gagtggcgcc attgtcttgt ctaaggaaaa ggctattgat tttctgaacc aatacgaatc
     2821 cacccattct atcgctgtca tcaaagaaaa tattcgccat aatattcgtg agcaggaaaa
     2881 ggcaatggag catttaacag tgcttgttaa tgagtttctg atgcaaagcc aatcaatcag
     2941 caagcaatac ccgctggcac cttacgaaat tatttgtagt caggattcag agcattttgg
     3001 ccaatccatt ggtgatttga acatttggca tcaaacggga gcgacgattg tagctattga
     3061 gcatgatggc caattcattg tttctcccgg tccttacgct gttatcgaaa aaggtgatca
     3121 tatttacttt gtcggtaatg aggacgtgat ttctagaatg aaaacctttt ttaatgttag
     3181 aaagggtctg taatcacaaa aaaacacaga gctgctttaa ggtgatggtg atatcacgat
     3241 gaagtgtctc tgtgtttttg tgttatcagg ctaaggcttc taagtagctt atagctctga
     3301 ttgaagcccc tagattactt tttcaaagcc aacagttttc aggataatag ctgtcatgtc
     3361 atcggttgtt tcttgacagt catgactaat ccagtagcta atcagacttt caatactggc
     3421 tagataaacc tcaagcgcgt agtgataagg gatctgatag tgcttggtga tgatttcttg
     3481 aaagccatca atagtggtca aaaattgata aataaaatcc ttgagtattt gtgaaaaatt
     3541 caaataactg gagttagcca tagcagcaat aaagggaaga ttatcaatga tataagcgag
     3601 ggcttccttt agaacgagtc tagtatctgt aaaaatatga gggtcattta ggagctggta
     3661 taaatcgtct aaggtgtcat ttatgagatg agtcatcata tcatgtttat ccctgtaatg
     3721 cagataaaag gtgcctctat tgacaccagc ttttttggtt aagtcagaaa cggtaatggt
     3781 ctcaaagctc ttttctgtca aaagactgac aagtgcctgc ttcaaatagg ccttggttgg
     3841 tgtgtgtctt gttgtcatcg actcatctcc ttaagtcaac aaatgctgct tatctgttct
     3901 tgttaaagtc ttgaggacat tatataataa ggctagtata aaatcaacaa ggtgttgata
     3961 taaaggaggt gacatgatca gtgtcctata ttgaaatgag gtcctcttca aagacctacc
     4021 agattggaga aacaactgtt aaggctaatg atgaggtatc ctttgagatt gaaagagggg
     4081 agcttgtgat cattttagga gcctctggtg caggcaagtc cacagtgctt aatattttag
     4141 gcggcatgga tagcaatgac caaggtcagg tcataataga cggcaaggac atctcgacct
     4201 atagtaaaaa ggcattgacc agctaccgtc gttacgaggt tggctttgtt tttcaatttt
     4261 acaatctggt gccaaatctg acagcaaagg aaaatgttga gctggcggct gatattgtgg
     4321 cagatgcact tgatccgact actgtcttaa atgaggtggg gctaggagga cgtttggagc
     4381 atttcccagc acagctatca ggaggtgagc agcaaagggt gtctattgct cgtgccttgg
     4441 ctaaaaatcc taagttgttg ctttgtgatg agccaacagg ggctttagat tatcaaaccg
     4501 gcaagcaaat tttaagattg cttcaagata tggcgcacga caagggcagg acagttattg
     4561 tggtgacgca taatactgct ctagcgccta ttgctgatcg ggtcatttat atgcatgacg
     4621 gtcgtgtgac caagacagtg cttaataagc agccgcttga tattgatagg ataacgtatt
     4681 gagaggtgcc tagatgaaac aaaaaacctt atggaaggat agttttcgag caataaaagc
     4741 tagtaagggg cgttttttgt ccttgctatt tttaatggct ctaggctcct ttgccttggt
     4801 tggcttaaag gtggctggtc ccaatatgga aaaaactgct agtcactatc tagaggagca
     4861 tcaggttatg gaccttagta tcctagcctc gcatggcttt tctgatagag ataagcaaga
     4921 attagcctct cttaaaaatg caagactaga gtatgcgagc tttgttgatg gtgcttttga
     4981 tcaccagagg aaggctatta ggctttattc tatgccacaa agcctatctc aggccagctt
     5041 ggtcaaggga gattacccta gcaaggctag cgacattttg ctatctgaag ctttatcaag
     5101 ccgctatcgg cttgggcaaa taatcacgat aagcctaaaa acaaagggat tgctaaagca
     5161 tagatcctat cgtgttgtcg gctttgctca ttctccagaa atatggtcca aaacaaactt
     5221 aggtgtttcc tcagcagggg atggtaatct ctatgcctat gcctaccttc accctagtgc
     5281 ctttcagcaa gggcacaatc tcttacgcat tcggtatgat gatttaagag ggttgaatgc
     5341 cttttcaact caatacaatg aacgattgct acaacaccaa gcagagcttg atcagatctt
     5401 gcaggacaat ggtcaagagc gttatgaaga aatgctcaat gaccttaatc gcagcttgaa
     5461 agatagtaaa gttaagctcg aagagcaaag gactgttctt aaggcaagtg aagaccagct
     5521 ggctttgcta agtggtcatg ccttagagca agcgcagact cagctaaagc aagggcagga
     5581 agagttagct aaaaaagaag caagcttgct agagttagct gaaaagcaaa gggcagcgat
     5641 gatcaagcca acctatacta gctatagtcg ctcaacgctg ccaggtggtg agggttatca
     5701 aacctatgcc acctcaacac agtccatatc gcatgttgga aatatctttc ctgttgtttt
     5761 gtatttggtt gcggccttag ttacttttac aacaatggct cgctatgttg acgaagaacg
     5821 aacgaactca ggcttactaa aggcaatagg ctattctgat tgggatatta ccaaaaaatt
     5881 tctgctatat ggtgccttag ctgccttgtt gggcactgga ttaggagttt taggagggac
     5941 ttatttttta tctcggctca tctcagctat cctaacagat gcattgacta tcggctctac
     6001 tcagctttat ttttattgga gctatagtgt ggttgcagtg cttttagcct tgttatctgc
     6061 tgttttgaca gcttatatgg tggtgagacg tgagcttttt ctcagaccct cacaactgtt
     6121 gctgcctaag cctcctagta gcggggcaag gatttggctg gagcatgtct cctttatctg
     6181 gcggcgttta tcctttacct ataaggttac ttttcgaaat atctttcgat ataagcaaag
     6241 aatgctgatg acagtaattg gagtagcagg ttctgttgcg ctcttatttt ccggcttggg
     6301 cattcaatcc tcacttgcta atagcctaag ctatcaattt ggcaagctga cagcctatga
     6361 catgctcgtg gtagaagctc caacagcaga agctcatgat aggcaggagc tggcacaata
     6421 tttgaaggca gatcagattg ctagtaagaa agagatttat tacgctaact tatcactaaa
     6481 gataaaagac ttagacaaca agcaaacagt gtcgttgatt tctagcgatc agagcactct
     6541 atctccctat tttagcttga ttggtgctgc tgaccgaaaa aagctagacc ttccaagtac
     6601 tggagtgctt atctcaaaaa agcttgctga ctattatcag gctcatgcag gagatcagct
     6661 tgagcttgaa gctagtaacg gtaaacgcta tcagttaaga gtgagtcagg ttattgacat
     6721 gactgttggt cattacttgt tcatgtctaa atcttattat cagcaggtat ttcgggatat
     6781 ggaggcttca ccatcctatt tggtaacaac agcaaaggct agtccatctg ctgtaaagga
     6841 cgtagctagt cagctcttag caatgcctgc ggttcaggct gtgtcacaac acagtagtat
     6901 tgttgctact gtgacaggga ttgtggcgtc tttggatcag gttatgacgc ttttagtact
     6961 tctatcagtt ctactagcct tggtcatttt gtatcatttg accaatatca atattgctga
     7021 gagggttagg gaattatcaa cgataagagt cttgggcttt tatgacaagg aggttacctt
     7081 atacatttac cgggaaacca tgcttttgtc tgctgttggt attttgatcg gtctctgggg
     7141 tggcagctat ttgcacgcct atatcatgaa ggtgattgct aatgattcta tgagctttgg
     7201 taggacagtt gatgcttatg tttacctagt acctgttggg gctattgtgc ttttgttgat
     7261 tgtgcttggc tatatggtta gctaccggct aagaaagatt gatatgctag aggctctaaa
     7321 gtctgttgat tagggtaaaa tagtacttga aaatcgctta ataatatgct agtattaaaa
     7381 tactataatt taatagaagg atacttttat ggaagcgatg atagctgcct atttggctga
     7441 tcatagagaa aagataccac ttggtcaggt tgttgattgc tttaagggga aggctgtttc
     7501 tcgtaaggct gaggctggtg aatttggttt gattaatctg tctgatatgg gacagctagg
     7561 aattgactat catcaggtta gagcctttca tatggataga cgacaactat tgcgctatat
     7621 cttagaggat ggagatgtct tgattgcctc aaaggggact gttcagaagg tttgtgtttt
     7681 tcataagcaa gaaagggaaa tggtagcgtc ctctaatatc acagtgctgc gtcctcagag
     7741 ggttttgcga ggctattata ttaagttctt tttggagtct gctattggtc aagccttgtt
     7801 aaaggcggcg gatcatggaa aggacgtgat taacctatcg accaaggctt tacttgatat
     7861 ccctgtacca gtgattcctt tggttaagca ggattatttg attaatcaat atttgcgagg
     7921 cctgcatgac tatcaacgga aagtaaacag agctgagcag gagtggcagt ttattcaaaa
     7981 tgaaattcaa aaaggcttgg gctagaggta aaatgtgagc ttaattgaac gaacaataaa
     8041 aatgctatta gcaacgatgg ctgcaatctt tcttgcctct cagctacagc tgtcttatgc
     8101 catatcagcg ggaattattg ccctgttagg tgtgctagac actagaaaat ctagcttaat
     8161 tgttgctaga aagcgtctgc tgtctttttt cttagccttt gctgtggcgg ttagtctatt
     8221 tgccttattt ggctttggtc tgctttccat tggcttgtat ctagcgctaa ccattccttt
     8281 gctttatcag ctgaaaatag aggcaggtct tgttcctatc actgtcttgg tgactcacct
     8341 gatgtctgag cagcgtattg atttgtcaat tctttttaat gagctgttgc tgtttttgat
     8401 tgggacgggt cttgcccttc ttgttaacgg gtatatgggg tctcaggagc atcgcctacg
     8461 cttgtaccac caaaagatag aagatagctt aaaggctatc ttgtaccgtt ttgaatcctt
     8521 tttgttagaa ggccaaggac aaaacgaggg acagatgatt aaggaattag agcttagctt
     8581 agatgaggcg ctaaagctgg tttatcgcga aaggcacaat accctctttt atcataccaa
     8641 ttatcaggtg cattattttg agatgagacg tcatcaaaat agattgttgg cgcaaatggc
     8701 cttaaatgtc actcagctaa catctcaaag cagagaaagt ctcctgctct cccatctttt
     8761 tcatgagaca gctcgtcagc tgagtgagaa gaattctgct ttgacattga ttgatgatat
     8821 tgagcaattg cttgaggtct ttaggcaaag agagctgcct cagactagag aggaatttga
     8881 aagacgggcg attctgtttc agctgttgca ggatttggag cgctttattc tactgaaggt
     8941 agaattttat cgtgattaca aggaagagca ggcatagtag ctgcttgctg ctgtgattaa
     9001 gagtctggaa aaatcatttt ctaggctttt ttgctata
//
LOCUS       DARYXW010000079         8867 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.079, whole genome shotgun sequence.
ACCESSION   DARYXW010000079 DARYXW010000000
VERSION     DARYXW010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8867)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8867)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8867
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.079"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            8..493
                     /locus_tag="TV191_001546"
     CDS             8..493
                     /locus_tag="TV191_001546"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEL1508043.1"
                     /translation="MPKEVIVESFELDHTIVKAPYVRLISEEFGPQGDVITNFDVRLV
                     QPNQAAIETAGLHTIEHLLAKLIRQRIDGMIDCSPFGCRTGFHLIMWGKHSSTDIAKI
                     ITSSLEEIATSITWEDVPGTTIESCGNYKDHSLFAAKEWAQLILKQGISDDPFNRHVT
                     S"
     gene            complement(638..2089)
                     /locus_tag="TV191_001547"
     CDS             complement(638..2089)
                     /locus_tag="TV191_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508044.1"
                     /translation="MSEKSKAFESEAESQNLELHEAKKMTIGEAVRKDSELKAGITED
                     DSVLDKYIKRHRNEVSSQKFDAKYMELDTASLDNFIKKQREELSKAGLVDVEPVDEAS
                     TEEKPAGETSFIEPLAARADTSAAATDSASDFTGQLADDAVSERPAEVESILSDSYAS
                     RRSKKKKPLFAILLATLTLVASAFALNHIYQLSKHKPQSKATVSKKARSKASTANQTN
                     KTKANAKAFEDLYKTFFTDNDKTTLKNSAFDQLPNLETALKRLEGTAYYDKAKEKVTG
                     LKKQVTAIQAVNGKFTTAAIVNGEKIAAEVKADANFDDLASDTLTTGNAKLDSLLQSS
                     IKAGREQLASRSATQAASTPAASALPASPAAPEVPAVPAPVAPMYGITGYDPSILQRD
                     LSRVPYNQAMIADTGNPAWAFNPGVLERIVATSQARGYISGNDYILEPVNIINGNGYY
                     NMFKPDGTYLFSLNCKTGYFVGNGKGHAEDLDY"
     gene            complement(2103..3257)
                     /locus_tag="TV191_001548"
     CDS             complement(2103..3257)
                     /locus_tag="TV191_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEL1508045.1"
                     /translation="MKEQFTLVATAAAGLEAVVGKELRALGFDCRVDNGKVFFEGDIE
                     AIAKANLWLRAADRIKIIVGQFPARSFEELFQGVFALDWEHYLPLGARFPIAKAKCVR
                     STLHNEPSVQAITKKAIVRKLQQHFHRPEHIPLQEVGAEFKIEVSILKDQATLMIDTS
                     GSSLFKRGYRVEKGGAPIKENMAAAILKLSNWFPDKPLVDPTCGSGTFCIEAALIGMN
                     IAPGFNRSFAFEEWSWVDKDRVQKVRDAAEKEANYDIELDISGFDIDGRMVELAKRNA
                     EEAGLADIITFKQMRLQDFRTDKINGVIISNPPYGERLLDDKAVDILYNEMVQVFAPL
                     VTWSKFILTSDDHFEQKYGQKADKKRKLYNGTLRVDLYQFYGERVKRNLI"
     gene            complement(3321..3689)
                     /gene="rnpB"
                     /locus_tag="TV191_001549"
     ncRNA           complement(3321..3689)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="TV191_001549"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(3702..4025)
                     /gene="gpsB"
                     /locus_tag="TV191_001550"
     CDS             complement(3702..4025)
                     /gene="gpsB"
                     /locus_tag="TV191_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEL1508046.1"
                     /translation="MTGIIYSPKDIFEQEFKTSMRGFDKKEVDEFLDNVIKDYEYFNA
                     QIEALKAENEALKKAKAQVRDPLAGSSQAVSQPTRVAQSATNFDMLKRISKLEKEVFG
                     KQIIE"
     gene            complement(4147..4662)
                     /locus_tag="TV191_001551"
     CDS             complement(4147..4662)
                     /locus_tag="TV191_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEL1508047.1"
                     /translation="MTAILVTGYRSFELGIFSEKDKRVAIIKKAIERDLIAYLEEGVD
                     WFIFTGNLGFEQWALEVANDLKKTYPLKTATIFAFETHGSTWNDRNQQQLQQFRETDF
                     VKYSYPSYESPKQLKSYHHFLIHNTDGAYLFYDSEHETRLSYLVAAMKEQPCYPLSFL
                     NFERLNDIADE"
     gene            4738..5346
                     /gene="recU"
                     /locus_tag="TV191_001552"
     CDS             4738..5346
                     /gene="recU"
                     /locus_tag="TV191_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEL1508048.1"
                     /translation="MVNYPHNPIRQKVTPLQKQQKHKQVDFANRGMSFEASINATNAY
                     YLAKGIAVIHKKPTPIQIVKVDYPRRSRAKIVEAYFKQASTTDYSGIYKGHYIDFEAK
                     ETRQKTAMPMKNFHAHQIEHMAAVLKQKGICFVLLHFATLKETYYLPAKALIDFYQID
                     RGNKSMPLDYIRKNGFEVKLGAFPQVPYLDIIEQKFLGGDYN"
     gene            5333..7498
                     /locus_tag="TV191_001553"
     CDS             5333..7498
                     /locus_tag="TV191_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL1508049.1"
                     /translation="MITINNPKILKFLKYTLGAILSLIIVTITLGGLLFAYYISSAPK
                     LSEAQLKSTNSSLVYDGNNHLIADLGSEKRENVTADSIPINLVNAIISIEDKRFFNHR
                     GVDLYRILGAAFHNLTSKTTQGGSTLDQQLIKLAYFSTNESDQTLKRKAQEVWLALQM
                     ERKYTKQEILTFYINKVYMGNGNYGMLTAAKAYYGKDLKDLSYAQLALLAGIPQAPSQ
                     YDPYTQPETAQSRRNIVLQQMYAEKNITKAEYEAAIATPISEGLQPLQQRASYPKYMD
                     NYLKQVIEQVKAETNKDIFTSGLKVYTNIIPEAQKKLYDIYNSEDYVYYPDADFQVAS
                     TVIDVTNGHVIAQLGGRNQDTNVSFGTNQAVLTDRDWGSTMKPITDYGPAIESGAYNS
                     TAQTTNDSVYYWPGTHTQLYNWDRRYYGWMTIQAALMQSRNVPAVRALEAAGLSYAQS
                     FLSDLGINYPEMHYSNAISSNNSSSDSKYGASSEKMAAAYAAFANGGLYYKPQYVNKI
                     EFSDGTSKVIENKGKRAMKETTAYMMTDMLKTVLTYGTGTAAAIPGVAQAGKTGTSNY
                     TDEELAQIVETHGLSPDYVGTMAPDENFVGYTNRYAMAVWTGYKNRMTPIYGYSLEIA
                     SHVYRNMISYLTGGYSDDWTMPSGLYRSGGFLYLSGTYTNSSDYTSSVYNNLYGNNSS
                     ASSQSSDEDTTEDSHSEANDSTTSSSEQQSSSTDDKKTN"
     gene            complement(7541..>8867)
                     /gene="pepC"
                     /locus_tag="TV191_001554"
     CDS             complement(7541..>8867)
                     /gene="pepC"
                     /locus_tag="TV191_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014678181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEL1508050.1"
                     /translation="LTETFTEQLYANYEANAKYLALENAITHNGLLKSLETRQSEIDN
                     DFVFSIDLTKDKVSNQKASGRCWMFAALNTFRHKLISEFKLEDFELSQAHTFFWDKYE
                     KSNWFMEQVIATADQALTSRRVKFLLDVPQQDGGQWDMVVALFEKYGVVPKSVYPESV
                     SSSNSRELNQYLNKLLRQDAQILRDVISAGADHQAVQAKKEELLQEIFNFLAMNLGLP
                     PRQFDFAYRDKDNHYHADKGITPQAFYEKYVGLKLSDYVSVINAPTADKPYGKSYTVD
                     MLGNVVGSPEVRYLNLDMERFKELAIKQMQAGESVWFGSDVGQVSDRQKGILALNTYD
                     FQAGMDIQLSQDKAGRLDYSESLMTHAMVLTGVDLDDTGKPIKWKVENSWGDKVGDKG
                     YFVASDAWMDEYTYQIVVRKDLLTADELAAYEAEPQVLAPWDPMGALAK"
BASE COUNT         2543 a         2082 c         1711 g         2531 t
ORIGIN      
        1 gtttcttatg ccaaaagaag ttattgttga aagctttgag cttgatcata ctattgttaa
       61 ggcaccctat gtacggctaa tctccgagga atttgggccc cagggagatg tgattacaaa
      121 ttttgatgtt cgacttgttc agcctaatca ggctgccatt gagactgccg gtttacatac
      181 cattgagcat ttattagcca agctcattcg tcaacgcatt gatggaatga ttgattgctc
      241 cccctttggc tgccgcacag gctttcacct catcatgtgg ggcaagcata gctcaacaga
      301 tattgctaag atcatcacgt ccagcctaga ggaaattgct acaagcatca cttgggagga
      361 cgttcctggc acaaccattg aatcctgcgg caattataag gatcacagcc tttttgctgc
      421 taaggaatgg gcacagctta ttctcaagca agggatctct gatgatccat ttaaccgcca
      481 tgtcacctca taaaacgaaa gcctctcttt tctgctaatg tgaaggaggc ttttaatgta
      541 ttcaaaaagg tgccaaaggc aaggctcaat gcccttacct ttagcacctg tgataactag
      601 agtatccagt tcaggatcac accttgtctt ctaagcatta atagtctaag tcctctgcat
      661 gccccttgcc atttccgaca aaatagcctg ttttgcaatt caatgaaaag aggtaggtgc
      721 catcaggctt aaacatgttg taatagccat tcccattgat aatattgacc ggctctagga
      781 tataatcatt gcctgaaata tagccccttg cttgtgaggt agccacaata cgctcaagca
      841 cacctggatt aaaggcccaa gcagggtttc ctgtatcagc aatcatagcc tgattgtagg
      901 gcacacgaga caggtcacgc tgcaatattg aagggtcata gcctgtaatg ccatacattg
      961 gagccactgg agctggtaca gcaggaacct ccggagctgc agggcttgct ggtaaggcag
     1021 aagcagctgg agtgctagct gcttgggtag cagacctgct tgctagctgc tcacgacctg
     1081 ccttgatgct tgattgtagc aatgaatcaa gttttgcatt accagtggtt agcgtatcac
     1141 tagctaggtc atcaaaatta gcatcagctt tgacctcagc tgcaatcttt tcaccattga
     1201 caattgcagc tgttgtaaat ttcccattaa ccgcctgaat agctgttact tgctttttca
     1261 gcccagtaac cttttcctta gccttgtcat aataggctgt cccttcaagc ctttttaaag
     1321 cagtctccaa attcggtaac tgatcaaagg cgctattttt tagggttgtt ttatcattat
     1381 ctgtgaaaaa tgtcttgtaa agatcttcaa aagccttagc attagccttt gttttgttgg
     1441 tctgattagc tgttgatgct ttgctccttg cttttttaga aacagtagcc tttgactgag
     1501 gcttatgctt agacagctga tagatatggt tgagggcaaa ggctgaggct acaagggtta
     1561 gcgtggctaa caaaatagca aacagaggct ttttcttttt agacctacga ctagcatagc
     1621 tatctgataa aatactctct acttctgcag gtcgctcgct aactgcgtca tcagctagct
     1681 gcccagtaaa atcactagca gaatcagtag ctgccgctga agtgtcagct ctagctgcta
     1741 gaggctcaat gaatgaggtc tcaccggctg gcttctcctc tgttgaagcc tcgtccactg
     1801 gctcaacatc aactaagccg gctttgctga gctcctctct ttgttttttg ataaagttat
     1861 ccagacttgc tgtatctaac tccatatact ttgcatcaaa cttttgtgat gacacttcgt
     1921 tacgatgccg cttaatatat ttgtctaaaa cactatcatc ctcggtaatc cctgctttta
     1981 gctctgagtc cttgcgtact gcctcaccga ttgtcatttt tttggcttca tgaagctcca
     2041 aattttggct ttctgcctct gattcaaatg ctttgctttt ttctgacacg ttttttacct
     2101 ctctatatca gattgcgctt taccctctct ccataaaatt gatacaaatc aacccttaga
     2161 gtaccattat aaagcttacg ttttttatca gctttttgac catatttttg ttcaaaatga
     2221 tcatcactcg tcaaaataaa cttgctccag gtaactaatg gagcaaagac ctgtaccatc
     2281 tcattataca agatgtctac tgctttgtca tcaagcaaac gctctccata aggaggattt
     2341 gaaatgatga caccgtttat cttgtctgta cggaaatcct gcaagcgcat ttgcttaaag
     2401 gtaatgatat cagccaagcc agcctcctca gcatttctct tggcaagctc aaccatacga
     2461 ccgtcaatat caaagcctga aatatccagc tcaatatcat aattagcctc tttttcagca
     2521 gcgtcacgaa ccttttgaac acgatctttg tccacccagc tccattcctc aaaggcaaag
     2581 gagcgattaa agccaggagc gatattcatt ccgatgagag ccgcctcgat acaaaaggtc
     2641 cccgatccac aggtgggatc aaccaagggc ttatccggaa accaattaga cagcttgagg
     2701 atagctgctg ccatgttttc cttaatagga gctccccctt tttccacccg gtagccacgc
     2761 ttaaataggc ttgagccact agtatcaatc atcagggtag cctgatcctt taagattgag
     2821 acctcaattt tgaactcagc ccccacctct tgaaggggaa tatgctccgg tctatgaaaa
     2881 tgctgctgca attttctgac aatggctttt ttggtaatgg cttgaacact tggctcgttg
     2941 tgcagggttg acctgacaca cttagccttt gcaataggaa acctagcacc taagggcaaa
     3001 taatgctccc aatccaaggc aaatacgccc tgaaacagct cctcaaagct tcgtgctggg
     3061 aactgaccta caataatctt aatacggtca gccgctcgca gccaaagatt tgctttagca
     3121 atagcttcaa tatcgccttc aaagaagacc ttgccattat ctactcggca gtcaaatccc
     3181 aaggccctta attccttacc cacaacagcc tctaggccag ctgctgcagt tgctactaat
     3241 gtaaattgtt ctttcatatg actctttcta tcctaaccaa ataaaagcta gcatatgcta
     3301 gcttaaccta ttatgcaatt ttctataagc catgttttgt tccagaaata actaggtatt
     3361 atctccttcg ataatcatct gtctactgtt tgtcaacagt caggatagct tgttcgtttc
     3421 caactatccc atgcccctac caaagtttgg gttgctagct tgaggggttt accgcgttcc
     3481 actttttacg tttccataaa aacttcgtca ctgtggcact ttcagagcta ctctggcata
     3541 tcaaggactt agccttttca ctcgccgtaa tgtgtcaaac acatccctag gcttatttgt
     3601 tcgcctagca caaacactac cagcatcaca gccggtgcta gcatggactt tcctcatagt
     3661 attgcaatac tacgcgatta tccaaaaatt gcacatctac attactcaat aatttgcttt
     3721 ccaaaaacct ctttttccag cttgctaatg cgctttagca tgtcaaaatt ggtggctgac
     3781 tgtgctactc tggttggctg tgataccgcc tgagagctgc ctgctaaagg atcacgcacc
     3841 tgagccttag ccttttttaa ggcttcattt tcagccttta gggcctcgat ctgagcattg
     3901 aaatactcat aatccttgat gacgttatca aggaattcgt cgacctcctt cttatcaaag
     3961 ccacgcatac tggtcttaaa ttcttgctca aaaatgtcct ttggactata aattatacct
     4021 gtcattctat actctccaaa cggtcaatct ttttcaaata tcaaactttg atatcactac
     4081 ttatggtaca gaaaaataaa ttaaaaagca agtatttaaa taccagtgat ttttaaatat
     4141 cactagctac tcatctgcaa tgtcatttaa acgctcaaag tttaggaaag aaagggggta
     4201 acagggctgc tccttcatag ctgctaccaa atagcttagg cgcgtttcgt gctcactatc
     4261 ataaaaaaga taggctccgt ctgtattgtg aatcaaaaag tgatggtagc tctttagctg
     4321 tttagggctt tcatagctgg gatagctata tttgacaaaa tcagtctccc gaaattgctg
     4381 cagctgctgc tgattgcgat cattccaagt gctgccatgc gtttcaaagg caaaaatagt
     4441 cgctgtcttt aaggggtagg tctttttgag gtcattagct acctctaaag cccactgctc
     4501 aaaccctaaa ttcccagtaa aaataaacca gtctaccccc tcctcaagat aagcaatcag
     4561 atctctttct atcgcttttt tgataatggc aactctttta tccttttcac taaagatgcc
     4621 cagctcaaaa cttcgatagc ctgttacgag aattgcagtc attagatgtt atcctttcaa
     4681 aaatatgtta taatgtgaat gcttaaatta ttattaagtc atgatgttag gagaacaatg
     4741 gttaactacc ctcataatcc tattcgccaa aaggtgaccc ctcttcaaaa gcagcaaaag
     4801 cacaagcaag tagactttgc taatcgtggt atgtcctttg aagcatccat taatgcaacc
     4861 aacgcttatt acttggccaa gggcattgct gtcattcata aaaagccaac tccgatacag
     4921 attgtcaagg tagactatcc aagacgtagt cgagccaaga ttgttgaggc ttattttaag
     4981 caggcttcaa cgaccgacta ttctggtatc tacaaagggc attatattga ttttgaagct
     5041 aaggaaacaa gacaaaaaac agctatgcca atgaaaaact ttcacgcgca tcagattgag
     5101 cacatggctg ctgttttaaa gcaaaaaggc atttgctttg tcctccttca ctttgcgaca
     5161 ctaaaggaaa cctattatct acctgccaaa gcactcattg atttttatca gattgatagg
     5221 ggcaacaaat caatgccact tgattatatc agaaaaaacg gctttgaggt caagctggga
     5281 gcatttccac aggttcctta tttagatatt atagaacaaa aatttttagg cggtgattac
     5341 aattaacaat ccaaaaatcc ttaaattcct gaagtataca ttaggtgcta tccttagcct
     5401 tatcattgtg acaattacct taggtggcct tttgtttgct tactatatca gcagtgcccc
     5461 taagctttct gaggcccagc tcaaatcgac caattccagt cttgtttatg acggtaataa
     5521 tcatttgatt gctgacttgg gctctgaaaa gcgtgaaaat gttacagctg acagcattcc
     5581 tattaatctg gtcaatgcta ttatttctat agaagacaaa cgctttttta atcatcgggg
     5641 ggttgatctc tatcgtatct taggtgcagc ctttcacaat ttaacaagca aaacaaccca
     5701 aggggggtct acacttgatc agcagctgat taagctagcc tacttctcga caaacgagtc
     5761 tgaccagacc ttgaagcgaa aagctcagga ggtttggctg gcccttcaaa tggagcgaaa
     5821 atataccaag caagaaatcc tgaccttcta catcaacaag gtttatatgg gaaatggtaa
     5881 ttatggtatg ctgacagcag ccaaggctta ttatggcaag gatttgaaag atttgtccta
     5941 tgctcagcta gccttgctgg cagggattcc acaggcccca agccagtatg acccctacac
     6001 acagcctgag acagctcaaa gccgccgaaa tattgtcctt cagcaaatgt atgctgaaaa
     6061 gaacattacc aaggctgagt acgaagcagc tatcgccaca cctatatcag aaggcctaca
     6121 gcctctccag caacgcgcca gctatccaaa atatatggat aattacttaa aacaggtgat
     6181 cgagcaggta aaggctgaga ccaacaagga tatctttacc tctggtctaa aggtttacac
     6241 aaacatcatt ccagaggctc aaaaaaaact ttatgacatt tacaattctg aggactatgt
     6301 gtattaccct gatgctgact ttcaggttgc ctcaaccgtt attgatgtca caaatggaca
     6361 cgttatcgcc caattaggag gacgcaatca ggataccaac gtttcctttg gaaccaatca
     6421 ggctgtctta accgatcgtg actggggatc caccatgaag ccgatcacag actatggacc
     6481 tgccattgag tccggtgctt acaattctac agctcaaaca actaacgact ctgtctacta
     6541 ttggccgggg acacacactc agctctataa ctgggaccgg agatactatg gttggatgac
     6601 cattcaagct gctctcatgc aatcacgaaa cgtccctgca gttagggctc tagaggcggc
     6661 aggtcttagc tatgcacagt ccttcctcag tgatctaggc attaattatc cagagatgca
     6721 ttattcaaac gccatctcaa gtaacaatag cagttctgat tcaaaatacg gtgcaagcag
     6781 tgaaaaaatg gctgctgcct atgcagcttt tgccaacggt ggactctatt acaagccaca
     6841 atacgtcaat aaaattgaat tcagcgatgg gaccagcaag gtcatcgaaa ataagggcaa
     6901 gcgtgccatg aaagaaacaa cagcctatat gatgactgat atgctaaaaa cggtactaac
     6961 ctacggtaca ggtactgctg ctgctatccc aggagttgca caggctggta aaactggtac
     7021 ctcaaactat accgatgagg agctggcaca aattgttgag acacatggac tatctcctga
     7081 ttacgtggga acaatggcgc cagatgaaaa ctttgtcggc tacaccaacc gatacgctat
     7141 ggcggtttgg actggttata aaaaccgtat gacgccaatt tatggctaca gcctagaaat
     7201 tgcttctcat gtttatcgca acatgatcag ctatctcacc ggcggctaca gcgacgattg
     7261 gaccatgcca agtgggctct atcgtagcgg cggcttcctc tacctaagtg gtacctatac
     7321 aaacagtagc gattatacaa gctctgtcta caacaacctc tatggtaata acagctcagc
     7381 ttcaagccaa tcctcagatg aggatacaac tgaagacagc cactcagaag caaacgacag
     7441 cacaacgtca tcatcagagc agcaatcaag ctccaccgat gataagaaaa ccaactgata
     7501 acaaaaaact ggttcaaatg ttctgaacca gttttttcaa ttatttggct aaggcaccca
     7561 tcggatccca aggggcaagt acctgtggtt ctgcctcata ggctgctaat tcatcagctg
     7621 ttagtaggtc cttgcgaaca acaatctggt aagtatactc gtccatccaa gcatcagaag
     7681 caacaaagta tcctttgtca ccaaccttgt ctccccaaga attttcaacc ttccatttga
     7741 taggcttacc agtatcatct aaatcaacac ctgtcaaaac catagcatgt gtcattaagc
     7801 tttcgctgta atcaaggcga ccagccttgt cttggctcaa ctgaatatcc atacctgcct
     7861 gaaaatcata ggtattaagg gctagaatcc ccttttgacg atctgatacc tgaccaacgt
     7921 ctgaaccaaa ccaaacggac tctccagcct gcatttgctt aatagcaagc tccttgaagc
     7981 gctccatatc aagattaagg tagcgcacct caggactgcc aacaacatta ccaagcatat
     8041 caaccgtata agatttgcca taaggcttat cagctgttgg ggcgttgata acagacacat
     8101 aatcagacag ctttagacca acatattttt cataaaatgc ctgtggtgtg atgcccttat
     8161 cagcatgata gtgattatcc ttatcacgat aagcaaaatc aaattgacga ggtggcaaac
     8221 caagattcat ggctaagaaa ttaaagattt cctgaagtag ctcttctttt ttagcctgta
     8281 ctgcctgatg atcagcacca gcactgatca catctcgaag aatctgagcg tcctgacgca
     8341 agagcttatt gaggtattga tttagctcac gactattgct tgatgacaca gactctgggt
     8401 agactgattt tggcacaaca ccgtattttt caaacagggc tacaaccatg tcccactgac
     8461 caccgtcttg ctgcggaacg tccaaaagaa acttaaccct acggctagtc aaggcttgat
     8521 cagcagttgc aatcacctgt tccataaacc agtttgattt ttcgtatttg tcccagaaaa
     8581 aggtgtgtgc ttgtgacaac tcaaaatctt ctaatttaaa ttctgaaata agcttatggc
     8641 gaaaggtgtt taaggctgca aacatccagc aacgacctga agccttttga ttagagacct
     8701 tatcctttgt caagtcaatg gaaaagacaa aatcattgtc gatctcactt tgtcttgtct
     8761 ccaaggattt aagcaagcca ttgtgagtga tggcattttc aagagctaaa tatttagcat
     8821 tagcttcata attagcatat agctgttctg taaatgtctc tgttaat
//
LOCUS       DARYXW010000080         8713 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.080, whole genome shotgun sequence.
ACCESSION   DARYXW010000080 DARYXW010000000
VERSION     DARYXW010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8713)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8713)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8713
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.080"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            49..291
                     /locus_tag="TV191_001555"
     CDS             49..291
                     /locus_tag="TV191_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508051.1"
                     /translation="MISCTLLASLLLTGCHSLSLQLAEAVQEKPIQAVTVEDLTRHGI
                     AESLKAYLQTMGLTNEEAMKQYEEVLSDEIIQYFSS"
     gene            complement(413..1627)
                     /gene="thiI"
                     /locus_tag="TV191_001556"
     CDS             complement(413..1627)
                     /gene="thiI"
                     /locus_tag="TV191_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEL1508052.1"
                     /translation="MKYSEIMVRHGELSTKGKNRMRFINRLKANIQDVLSAYSEVTVR
                     STRDRTHVLLNGADDRSVIEALKPVFGIQGLSPVYKVEKSVPVLIAAVQEIMSSLYRE
                     GLTFKISSKRSDHQFELDSRDLNHTLGAAVFEALPHIKAQMKNPDVTLKVEIRDEAAY
                     LSHEDIKGAGGLPVGASGKGMLMLSGGIDSPVAGYLSLKRGVEIEAVHFASPPYTSPG
                     ALRKAKDLTQRLTRFGGNIQFIEVPFTEIQEEIKHKAPEAYLMTLTRRFMLRITDAIR
                     EKRKALVIINGESLGQVASQTLESMQAINAVTSTPIIRPVVAMDKLEIIDIAQQIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKLANVERYESRFDVDGLVERAVAGIRVTEITPEIE
                     TDSLSTLIEELL"
     gene            complement(1629..2771)
                     /locus_tag="TV191_001557"
     CDS             complement(1629..2771)
                     /locus_tag="TV191_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEL1508053.1"
                     /translation="MIYFDNAATTKPYEEALKTYQEVASKIYGNPSSLHQLGANASRI
                     LEASRRQIAALLDVEAKEIFFTSGGTESDNWAIKGIAFEKSHFGKHIIVSAIEHPAVR
                     ESAKWLESQGFELSYAPVTDKGVVDVKKLAALIRKDTILVSIMAVNNEIGSIQPIAAI
                     SELLADKPTITFHVDAVQAIGKLPVEAYLTARVDLASFSGHKFHAVRGVGFLYKKSGK
                     RITPLLVGGGQEDELRSTTENVAAIASMAKALRIITERQDRSQARIAAMKKVIYQALQ
                     AYEDTILFSEIDDFAPHILTFGIKGVRGEVIVHAFEKHEIYISTTSACSSKVGKSAGT
                     LVSMGIPAALAQTAVRISLDDDNDMGQVEQFLTIFKQIYEKTQKVR"
     gene            3011..3451
                     /locus_tag="TV191_001558"
     CDS             3011..3451
                     /locus_tag="TV191_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508054.1"
                     /translation="MSSHYSRQQKPKKSASIPTKHIKTGFTALQKTIALVGSVLSIVV
                     ATITINRALQPSNEQPKSDSSPSSTSTIVKIIEKESSHSNKEETDKTETNSDSSGTQA
                     THTTPSSADPATKDTEKQQNTETEAPAANQPTANEPAPNSTSNP"
     gene            complement(3521..4873)
                     /gene="gorA"
                     /locus_tag="TV191_001559"
     CDS             complement(3521..4873)
                     /gene="gorA"
                     /locus_tag="TV191_001559"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEL1508055.1"
                     /translation="MAIQYDYIVIGGGSAGIASANRAAMYGAKVLLAEGKAIGGTCVN
                     LGCVPKKVMWYGAQVAETIHTYAKDYGFTVLEDRFDFKTLKSNRQAYIDRIHASYEKG
                     FEHNGVDRIYDYARFIDQHTVDIAGKTYTAPHILIATGGQPIFPDIEGAELGISSDGF
                     FALDDIPKRTAVVGAGYIAVEIAGVLNALGSQTDLLVRYDRPLRTFDQDIIQVLVDEM
                     KVSGPRLHTNADVTKVTKANDGSLQVHLSDGRRLEVDQVIWAIGRKPNVTGFGLEHTG
                     VELDKKGYIAVDAYENTSVDGIYAVGDVNGKLALTPVAVAAGRRLAERLFHNKPNEKL
                     DYNKVATVVFSHPPIGSIGLTEEAAIQAYGQAAVRVYQSQFTSMYTAITSHRQPCLMK
                     LIVAGEEETIVGLHGIGYGVDEMIQGFAVAIKMGATKADFDNTVAIHPTGAEEFVTMR
                     "
     gene            complement(5067..5408)
                     /locus_tag="TV191_001560"
     CDS             complement(5067..5408)
                     /locus_tag="TV191_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEL1508056.1"
                     /translation="MSQDIYDYANKLERAVRALPEYRKALEAREEIKADEAASQLFDE
                     FVAVQEKLQGLMQTGQLPTETEQADIQALSQKIEANDLLKGYFNAQQALSVYVNDIER
                     IVFAPLKDLAK"
     gene            complement(5469..6635)
                     /gene="aroC"
                     /locus_tag="TV191_001561"
     CDS             complement(5469..6635)
                     /gene="aroC"
                     /locus_tag="TV191_001561"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEL1508057.1"
                     /translation="MRYLTAGESHGQALTAIIEGIPAGLALSAELINKELKRRQGGYG
                     RGARMRIESDRVHISSGVRHGKTTGAPITLTIQNKDHQKWLDIMAVEAVEEQIKFKRK
                     ITRPRPGHADLVGGIKYRFDDLRNALERSSARETAMRVAVGAIAKAILTELGIETANH
                     VLVFGGIEVAVPEAMSFADIKKVAESSDLSIVNPKQEATIKAHIDQVKKEGDTLGGII
                     ETLIHGLPAGLGSYVQWDRKLDAKIAQAVLSINAFKGVEFGMGFDMGYQKGSQVMDDI
                     IWHETSGYSRRTNRLGGFEAGMTTGQPIVVKGVMKPIPTLYKPLMSVDTETHEPYKAT
                     VERSDPTALPAAGVVMENVVATVITKEILEQFPSDNMTDLKQAFFAYRDYVHHF"
     gene            complement(6748..7428)
                     /locus_tag="TV191_001562"
     CDS             complement(6748..7428)
                     /locus_tag="TV191_001562"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEL1508058.1"
                     /translation="MKIVAPVMPRNVEEAQSIDVSKYQDVNLIEWRADFLPKEDIVSV
                     APAIFEKFAGREIIFTLRTSQEGGHITLSDQEYVDLIKEINAIYNPDYIDFEYFSHKA
                     VFHEMLDFPNLVLSYHNFDETPENLMEAFSEMTKLAPRVVKIAVMPQSEQDVLDLMNY
                     TRGFKTLNPEQEFATMSMGKLGRLSRLAGDVVGSSWTFVSLDQASAPGQVSLADMKRI
                     LHVLESED"
     gene            complement(7425..8588)
                     /locus_tag="TV191_001563"
     CDS             complement(7425..8588)
                     /locus_tag="TV191_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEL1508059.1"
                     /translation="MNKVCINPLVERKIAAGIQLLDEKDFDGTIWDYQLVQLVNSSHQ
                     LIGTAYLSKQHKGVGWYLGRSVKKLSVSYFVTLFKTAKKKREHFAASEWTNAYRLFNQ
                     DGDDFGGLTIDLYKDFALFSWYNVFVYQEKELIIQAFREVFPEVRGAYEKIRFKGPDK
                     ETAHLYGAFAPDTFTILENGVAYQVFLNDGLMTGIFLDQHEVRRGLVDGLALGKTVLN
                     LFSYTAAFSVAAAMGGAVETTSVDLAKRSRELSKAHFVQNQLDLSSHQLVVMDVFDYF
                     KYAKRKQLSFDLIIIDPPSFARNKKQTFSVSKDYHQLIAEALDLLAPKGTIIASTNAA
                     NMTVNQFKKQIIKGLGGRPLAQMTLEQLPSDFTINKADERSNYLKVFTIRVRE"
BASE COUNT         2559 a         2063 c         1623 g         2468 t
ORIGIN      
        1 ttttcatata attttcatga aaggagggaa atatatgaaa aatctatatt gataagttgt
       61 acactattag ccagtctctt attaactggc tgtcactcat tgtctttgca gctagctgag
      121 gctgttcagg aaaagcctat tcaagcggtt acggtagagg atttgaccag acatggcatt
      181 gccgaatcct tgaaagccta cctacagacg atgggcttaa ccaatgaaga ggctatgaaa
      241 caatacgagg aggtcctttc tgatgagatt atccagtatt ttagcagcta aataagagaa
      301 tttgagcaaa atcagctaaa aacaaaagcc agagccttta ataactaata ggtctggctt
      361 tttttgactg tttagataga ctgcttatgt tgtagggcta ggtgcgcacc tcctacaaca
      421 attcctcaat aagcgttgat aagctgtcag tttcgatttc aggagtgatc tcagttactc
      481 tgatccctgc cactgctcgc tcgaccaatc cgtcgacatc aaagcgagac tcatatcgtt
      541 caacatttgc tagcttggga ttggttttgg gacgatcagg agcaaaaata gtacagcagt
      601 cttcaaaggg ctgaatggaa atatcaaagg tgtcaatttg ctgagcgata tcaatgattt
      661 ctagcttatc cattgccaca actggtctga taatcggagt tgaagtgact gcattaatag
      721 cctgcatgct ctctaaggtc tggcttgcaa cctgtcctaa gctttcaccg ttaataatca
      781 ctaaagcctt tcgcttctca cgaatagcat ctgtgatccg cagcatgaag cgtctagtaa
      841 gtgtcatcaa ataggcttcg ggtgccttat gcttgatctc ctcttgaatc tcggtaaatg
      901 gaacctcgat aaactgtata ttacctccaa aacgtgttaa gcgctgcgtt agatccttgg
      961 cttttcttag cgcaccagga ctggtatagg gtgggcttgc aaaatgcact gcctcaatct
     1021 caacacctcg tttcagggat agatagcccg caaccggtga atcaatacca cctgatagca
     1081 tcagcattcc ctttcctgaa gctccaaccg gcagccctcc agctcccttt atatcttcgt
     1141 gagacagata agcagcctca tcacgaattt cgacctttag ggtaacatca ggatttttca
     1201 tctgtgcctt gatatgcggc aaagcctcaa agacggctgc tcctaaggtg tggttgaggt
     1261 cgcggctatc tagctcaaac tgatggtcac tacgcttgct ggatatttta aaggttagcc
     1321 cttcgcgata caaggagctc ataatctcct gaactgctgc tatcagtaca gggacacttt
     1381 tttcaacttt atagacagga gataagccct gaataccaaa caccggcttt aaggcttcaa
     1441 tcacagacct atcatctgca ccattaagta aaacatgggt cctgtctcga gttgatctga
     1501 ctgtcacctc agaataggca gaaagaacat cttgaatatt agcttttagc cgattaataa
     1561 accgcatacg gttttttccc ttggtcgata actccccatg acgaaccatt atttctgaat
     1621 atttcatatt atctaacctt ttgtgttttt tcataaatct gtttaaaaat cgttaaaaat
     1681 tgctcaacct gtcccatatc attatcatca tctaggctga tacggactgc tgtttgagcc
     1741 aatgctgctg gaattcccat tgagactaag gttcctgccg actttccaac ctttgatgag
     1801 caggcactcg ttgttgatat ataaatctca tgcttttcaa atgcgtgcac aataacctct
     1861 ccacgaacgc cctttatacc aaaggtcaga atatgaggag caaaatcatc tatctcagaa
     1921 aagagaatgg tatcctcata ggcctgcaag gcttgataaa taaccttttt catggctgct
     1981 atccttgctt gagatctatc ctgtctttct gtgatgatcc ttaaagcctt ggccatactt
     2041 gcaatagctg ccacgttttc agttgtcgaa cgtagctcat cttcttgacc gccaccgacc
     2101 aataagggag tgattcgctt tcctgatttt ttataaagaa agccaacacc acgaacagca
     2161 tgaaatttat gaccagaaaa agaagctaag tcaacacgcg cggttaagta agcctcaaca
     2221 ggaagcttcc caatagcctg aacagcatcg acatgaaagg taatggtggg cttatcagcc
     2281 aaaagctctg atatggctgc aatcggctga attgacccaa tctcattgtt aaccgccata
     2341 atggaaacta atatggtatc ttttcggatt aaggcagcta gctttttgac atcaacaact
     2401 cccttatctg tgacaggagc ataagacagc tcaaagcctt gactttctag ccatttggcg
     2461 ctttctctga cagctgggtg ctcaatggct gagacaatga tgtgcttacc aaagtgagat
     2521 ttttcaaagg caatcccctt gatagcccaa ttgtcgcttt ccgttccgcc agaggtaaag
     2581 aaaatctctt tggcctctac atcaagtaag gccgctattt gcctgcgcga agcctccaat
     2641 atacgactgg cattggctcc tagctgatgg agactagagg gattgccgta aatcttactg
     2701 gccacttcct gatacgtttt aagtgcctct tcgtaaggct tggtagtggc tgcattatca
     2761 aaataaatca tgtgtcacct tcatttttat tcaatacttt attgtatcac aaatttgatg
     2821 aaatgaaaaa atagatcttt ttgcaggata ggacaactct atcctagaca ataaggtaaa
     2881 ccgttgactt gatttttgtt ctagattata ctggtagatg atagagctaa gtctgaaatg
     2941 cctgttagcc attaaagacc taaagcattt gactttagct agcctatgac tcgttaaagg
     3001 agatattctc atgtcatcac attattcacg tcaacaaaag cctaaaaaat cagcaagtat
     3061 tcccacaaag catattaaaa ctggctttac cgcccttcaa aaaaccattg ccttagttgg
     3121 tagtgttctg agtattgttg tagcgacaat cactattaat cgagctctac aaccatcaaa
     3181 tgagcaaccc aaaagcgatt cctctccgtc atcaacatca acgattgtga aaattattga
     3241 aaaggagtcg tcacactcaa ataaggaaga gactgacaag acagaaacta attctgattc
     3301 tagcggtact caggcgacac atactactcc tagctcagct gatcctgcta ctaaggatac
     3361 agaaaaacaa cagaataccg aaacggaagc accggctgct aatcaaccca cagctaatga
     3421 gccagctcct aacagtacaa gcaatccata acacaaaaca cgataacagg caattcagat
     3481 aagctctgaa ttgtctgcta tcgtgtttta tcatgtgctg ttatctcatg gtaacaaact
     3541 cttcagcacc tgtagggtga atggcaacag tattgtcaaa atcagcctta gtagccccca
     3601 ttttaatggc aacagcaaag ccttgaatca tctcatcaac accataacca ataccatgca
     3661 gaccaacgat ggtctcttct tctcctgcaa cgatcaattt cattaggcag ggctggcgat
     3721 gactagtaat agctgtatac atggacgtaa attgtgattg atagacacga acagccgctt
     3781 gcccataggc ttgaatagct gcctcttctg ttaagccgat cgagccaatt ggcggatggc
     3841 taaagacaac tgtcgcaacc ttgttataat caagcttttc attgggctta ttatgaaaca
     3901 agcgctctgc caagcgacga cctgctgcga cagcgactgg ggtcaaagca agctttccat
     3961 taacatcacc aacagcatag atgccatcaa cagatgtgtt ttcataagcg tcaacagcaa
     4021 tatagccctt cttatccagc tcaactcctg tatgctccaa gccaaagcct gtcacatttg
     4081 gcttgcggcc aattgcccaa atcacttggt ccacttcaag cctacgacca tcggacaaat
     4141 gcacttgaag agagccatca ttagccttgg taaccttagt aacatcggca ttggtatgca
     4201 gccttggtcc agataccttc atctcatcga ccagaacctg gataatatcc tgatcaaagg
     4261 tcctcagtgg cctgtcatag cgaaccagca aatccgtctg agaacctagg gcattgagca
     4321 ctcctgcaat ctcaacagca atatagccag caccgacaac tgctgttcgt tttggaatat
     4381 catctaaagc aaagaaacca tctgagctaa tccccagctc agctccttca atgtcaggaa
     4441 aaataggctg accaccagta gcgattaaaa tatggggggc tgtataggtc ttacctgcaa
     4501 tgtcaaccgt atgctgatca ataaatcgtg cataatcata aatacgatca accccgttat
     4561 gctcaaagcc cttctcataa gaggcatgaa tacgatcaat ataggcctga cgattgcttt
     4621 ttaaggtttt aaaatcaaac ctatcctcta acaccgtaaa cccgtaatcc ttcgcatagg
     4681 tatgaatcgt ttctgctacc tgtgcgccat accacatgac ctttttaggc acgcagccca
     4741 aattaacaca ggtccctcca atagccttgc cctcagctaa taggacctta gcaccgtaca
     4801 ttgctgcacg attcgccgag gcaatcccag cgctcccacc accaatcaca atataatcat
     4861 actgaattgc cattaattta ccacctttac tcttaatgct tgcctcaata gatttgttat
     4921 taagctatca ttattgcttt attttaatct actgtcattt gactataaca taaaataact
     4981 tgtgtctcaa atccctgcta cgacaaaaaa agattgtgat aagcatcaac aatcctttct
     5041 tctcttaatc ctaagccagc ttagctctac ttggccaaat ccttcaatgg tgcaaataca
     5101 atccgttcaa tatcattaac atagacggaa agagcctgct gagcgttaaa ataccctttt
     5161 aataggtcat tggcctcaat tttttggctg agagcctgaa tatctgcctg ctctgtctct
     5221 gttggcagct gaccggtctg catgagtcct tgcaattttt cttgcacagc aacaaactca
     5281 tcaaatagct gactggcagc ctcatctgcc ttaatctctt ctctggcttc caaggccttg
     5341 cgatactctg ggagcgcacg aacagctcgc tcaagcttat tggcataatc ataaatatct
     5401 tgggacatct ggatctcctt ttatcattta ttatccttat catatcacaa tatcaagcca
     5461 tttgtcgctt aaaaatgatg aacatagtca cgataggcaa aaaaagcctg ctttaaatcg
     5521 gtcatattgt ctgatggaaa ttgttccaaa atctcttttg tgatgacagt tgctacaaca
     5581 ttttccatca cgacaccggc agccggcaga gccgtaggat cagaacgctc aacagtagcc
     5641 ttgtaaggct cgtgcgtctc agtatccaca gacattaggg gcttgtagag ggtgggaatc
     5701 ggcttcatca cccctttgac aacaataggc tgaccagtag tcatacctgc ctcaaagcca
     5761 cctagtcggt ttgttcgacg actgtagccg cttgtctcat gccaaatgat gtcgtccatg
     5821 acctgcgagc ctttttggta gcccatgtca aagcccatac caaattcgac ccctttaaag
     5881 gcgttgatag acaggacagc ctgcgcgatt ttggcgtcta atttacgatc ccactgaaca
     5941 tatgaaccta agcctgctgg taagccatga atgagtgttt caataatacc accaagcgta
     6001 tctccttctt ttttgacttg atcaatatgg gccttgatag tcgcctcttg cttgggattg
     6061 acaatagata aatcagaaga ctctgctact tttttgatat ctgcaaagga catcgcctca
     6121 ggcacagcta cctcgatacc accaaaaact aggacatgat tagcagtttc gatcccaagc
     6181 tcagtaagga ttgccttagc aattgcacca acggccacac gcatcgctgt ttctctggca
     6241 gaggagcgct caagcgcatt tcttaaatca tcaaaacgat atttgatccc cccaaccaag
     6301 tcagcatgac cagggcgtgg acgagtgatt ttacgcttga acttgatttg ctcttcaaca
     6361 gcctcaacag ccataatgtc tagccatttt tgatggtcct tgttttgaat ggttaaagta
     6421 attggtgctc ctgttgtttt gccatgacga acacctgaag agatatgcac acgatctgat
     6481 tcaatgcgca tgcgtgcgcc acgaccatat cccccctgcc gacgcttcag ttccttgtta
     6541 ataagctcag ctgataatgc taagcctgca ggaattccct ctataatggc cgtcaaagct
     6601 tgtccatgtg actcacctgc tgttaaatac ctcattattc ctccatttat caatcataga
     6661 cataaaaagc aaacctgccc tcctctagac aactaaaaga cattattcta agctatccaa
     6721 gagaataatg tctgttaccg tatcttatca atcctcagat tccaaaacat gaagaatcct
     6781 tttcatatca gccaaggaaa cctgccctgg tgcactggct tgatctaagg acacaaaagt
     6841 ccacgaggac cctacaacat cacctgccaa gcgtgatagt ctgcctagct ttcccattga
     6901 catggttgca aattcctgct ctgggttaag tgttttaaag cctctggtat aattcatcaa
     6961 atccaaaacg tcctgctcgc tctgtggcat gacagcaatc ttgacaacgc gaggagctag
     7021 cttagtcatc tccgaaaaag cctccatcag attttcaggc gtctcatcaa aattgtgata
     7081 agacaagaca agattcggaa agtcaagcat ttcatgaaag acagccttgt gactaaagta
     7141 ttcaaagtca atatagtcag gattataaat cgcattgatc tccttgatca aatcaacgta
     7201 ttcctgatca gaaagtgtaa tatgccctcc ttcttgactt gtacgaaggg taaaaataat
     7261 ctctctacct gcaaattttt caaaaatagc tggcgctaca gaaacaatat cctccttagg
     7321 aagaaagtct gctcgccact cgattaaatt aacatcttga tatttagaaa cgtcgataga
     7381 ttgagcctct tcaacatttc ttggcatgac tggtgctaca attttcattc tcgtaccctt
     7441 atagtaaata cctttaaata attacttctt tcatctgctt tattgatagt aaaatcactt
     7501 ggaagctgct caagtgtcat ctgagctaat ggcctgcctc ccaatccttt gataatttgc
     7561 tttttaaact ggttaacagt catattggca gcatttgttg aagcgataat tgttcccttg
     7621 ggggccaata ggtctagagc ctcagcgatt aattgatggt aatccttact cactgaaaac
     7681 gtctgctttt tgtttctggc aaagcttggt ggatcaataa taataagatc aaaagaaagt
     7741 tgctttcgct tagcatactt aaaatagtca aaaacgtcca taaccacaag ctgatgactg
     7801 gataggtcca actgattttg aacaaaatga gcctttgata actctctgga gcgctttgcc
     7861 aaatcaacag aggttgtctc aactgcaccg cccattgctg cagctacaga aaaagctgct
     7921 gtatatgaga acaggtttaa aacagtcttt ccaagcgcca agccgtccac cagacctcgt
     7981 ctaacctcat gctgatcaag aaaaatccct gtcatcaagc catcatttaa aaatacctga
     8041 taggctacgc cattttctaa aatggtaaag gtatcaggag caaacgcgcc atacaaatga
     8101 gccgtctcct tatctggtcc cttaaagcga atcttttcat aagctcccct gacctcagga
     8161 aaaacctctc gaaaagcctg aataataagc tccttttctt gataaacaaa gacattatac
     8221 caagaaaata aagcaaagtc cttatagagg tctatggtta gtcctccaaa atcatcaccg
     8281 tcttggttaa aaagacggta agcatttgtc cattcagacg cggcaaaatg ctctcttttc
     8341 ttcttagctg tcttaaataa ggtcacaaaa taagaaaccg acaatttctt aacagacctt
     8401 cctagatacc agcctactcc cttatgttgc tttgaaaggt aagctgtgcc gatgagctga
     8461 tgagatgaat tcacaagctg cactaactgg tagtcccaaa tggtgccatc aaaatccttt
     8521 tcatctagta attgtatccc tgctgctatc ttgcgttcaa caaggggatt aatacagacc
     8581 ttattcatag tttctattat aacaaaaact attaaaaaat catactagat ttaaacttat
     8641 tgcaagcatt agctccatat ttttggtata atttaatctg agattttatt tggagattat
     8701 atcttttagg aaa
//
LOCUS       DARYXW010000081         8649 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.081, whole genome shotgun sequence.
ACCESSION   DARYXW010000081 DARYXW010000000
VERSION     DARYXW010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8649)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8649)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8649
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.081"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            258..1097
                     /locus_tag="TV191_001564"
     CDS             258..1097
                     /locus_tag="TV191_001564"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEL1508060.1"
                     /translation="MLFIELLKAIFFGVIEGVTEWLPISSTGHLILVQEFIRLHQDKA
                     FMEMFNIVIQLGAIIAVIVIYFERLNPFQPGKSPQQIRLTWQLWLKVAIACIPSIIIA
                     VPLDDWFDAHFNHMLPIAIALIVYGIAFLWIEKRNQTLEPRVVKLSRMSYKTAFFIGC
                     FQVLSIIPGTSRSGATILGAIILGASRTVAADFTFFLAIPTMFGYSGLKALKFFIDGN
                     HLTLSQLLVLLVASLTAFAVSLYVIKLLTDYVKKHDFTVFGRYRIVLGSLLIVYSVFK
                     SLF"
     gene            1217..1981
                     /gene="mecA"
                     /locus_tag="TV191_001565"
     CDS             1217..1981
                     /gene="mecA"
                     /locus_tag="TV191_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEL1508061.1"
                     /translation="MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYAV
                     MDELGLPDNFKDSGMLSFRVTPRKDRLDVFVTKSDLNKDLNFEDLADLGDISQMTPED
                     FFRSLEQSMREKGDVNAHEKLEKIEEIMEDVVDATLAEQADSKEAAELDEPTEPLDYV
                     HYVLDFASVRDAVCFAKVIDFPIEASELYKGPRHYHMTILLDVQNKPAYFANVMYARL
                     IEHASPGTKTRAYLQEHGCQLIFDGAVEELQKIRLG"
     gene            1988..3145
                     /locus_tag="TV191_001566"
     CDS             1988..3145
                     /locus_tag="TV191_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HEL1508062.1"
                     /translation="MISFTIDDVLVLIGALLMSLLLTPIVRFLSIRVGVVDTPNARRI
                     NKVPMPTSGGLAIFTSFVIASLVLMPLASNGAHIGGQTYFQYILPVVLGGLVVTITGF
                     IDDVYELSPKLKMLGIVIGAIIVWAFTDFKFDSFKIPFGGPLLAFDPFLTFFLTVLWI
                     ISITNAINLIDGLDGLVSGVSIISLVTMAIVAYFFLPLTNFFLTLTILILIASIAGFF
                     PYNYHPAIIYLGDTGALFIGFMIGVLSLQGLKNATAVAVVTPVIILGVPIMDTIVAII
                     RRSLSGKKFYEPDKMHLHHRLLSMGFTHRGAVLVVYGIAMLFSLISLLLNVSSRIGGV
                     LLILGLLFALEVFIEGIEIWGEKRTPLFNLLKFIGNSDYRQTTLSKWKQRK"
     gene            3266..4036
                     /gene="sufC"
                     /locus_tag="TV191_001567"
     CDS             3266..4036
                     /gene="sufC"
                     /locus_tag="TV191_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014293969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEL1508063.1"
                     /translation="MSILEINNLHVSIEDKEILKGVNLTLRTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYQVTEGEILLDGVNILELEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAMNAGKEDRDKISVRDFITKLDEKMALLGMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPKFALLDEIDSGLDIDALKVVSKGVNEMRGQAFGAMIITHYQRLLNYITPDLVHV
                     MMDGRIVLSGDAALAIRLEKEGYAGIAEELGIDYKEEV"
     gene            4127..5389
                     /gene="sufD"
                     /locus_tag="TV191_001568"
     CDS             4127..5389
                     /gene="sufD"
                     /locus_tag="TV191_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEL1508064.1"
                     /translation="MTKEKILAFSQAHAEPTWLQELRLKAFDVMPHLELPTIERVKFH
                     RWNFGDGSLTESTALGTVPDFMALGDNPKLVQVGTQTVLEQLPMELIEKGVVFTDLAT
                     ALDEIPEQLEAHFGSALAFDEHRLAAYHTAYFNSAAVLYVPDHVEIEQPIEGIFLQDG
                     DSDVPFNKHVLIIAGKESKLTYLERFESIGDKTQAASANISVEVIAQAGSQIKFSAID
                     RLGDQVTAYISRRGRLDHAATIDWALALMNEGNVIADFDSDLIGQGSQADVKVVAASS
                     GRQVQGIDTRVTNYGKHTVGHILQHGVILERGTLTFNAIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENEVTAGHAASIGQVDPEDMYYLMSRGLDQETAERLVIRGF
                     LGAVVAEIPVPSVRQDIVTALDDKLARR"
     gene            5416..6642
                     /locus_tag="TV191_001569"
     CDS             5416..6642
                     /locus_tag="TV191_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEL1508065.1"
                     /translation="MFDPNQIKADFKLLDQYVNDEALVYLDNAATTQKPQAVLEAMQA
                     YYQKDNANVHRGVHTLAERATRQYEASRQKVADFIGAKSSKEVIFTRGTTSSLNWVGK
                     FAEQVLKPGDEVLISIMEHHANILPWQQVCQKTGARLVYAYLKKGKLDMNDLQSKLGA
                     STKFVSITHVSNVLGCVNPIQEIARLAHARGAYFVVDAAQSVPHMAIDVQELDCDFLA
                     FSGHKLLGPTGIGVLYGKEALLNQMNPVEFGGEMIDFVYEQEATWKPLPWKLEAGTPH
                     IAGAIGLGAAISYLEAIGMDQVHAHEADLVAYTLPRLQAIAGLTVYGPDRSDERSGVL
                     AFNIDGLHPHDLATALDYEGVAVRAGHHCAQPLHKYLGLHSTVRASFYLYNTREDCDR
                     LIEAILKAKEFFNGTF"
     gene            6629..7066
                     /locus_tag="TV191_001570"
     CDS             6629..7066
                     /locus_tag="TV191_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEL1508066.1"
                     /translation="MALSKLSSLYMAVVADHSRHPHHHGQLEGVEAVQLHNPTCGDVI
                     SLTIKFADDRIEDIAFAGDGCTISTASSSMMTDAVLGKTKEEALALADIFSNMVQGND
                     DSNQALLGEAELLAGVANFPQRIKCATLAWHALKQAIEKSDEF"
     gene            7106..8524
                     /gene="sufB"
                     /locus_tag="TV191_001571"
     CDS             7106..8524
                     /gene="sufB"
                     /locus_tag="TV191_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEL1508067.1"
                     /translation="MSDINETVAPQPIDLGDYQFGFHDDVEPIYSTGKGLNEAVVREL
                     SAAKDEPEWMLEFRLKSLEAFHKMPMQTWGADLSDIDFDEIIYYQKPSDKPARSWDDV
                     PDKIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKAEFEKLGIIFTDTDSALKEY
                     PELFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNEHTGQ
                     FERTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVY
                     NLVTKRARALKDATVEWIDGNLGAKTTMKYPSVYLDGPGARGTMLSIAFANTGQHQDT
                     GAKMVHNAPHTSSSIVSKSIAKSGGKVDYRGQVTFNKLSKKSVSHIECDTILMDDISK
                     SDTIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKE
                     LPMEYAVELNRLIAYEMEGSVG"
BASE COUNT         2307 a         1592 c         2136 g         2614 t
ORIGIN      
        1 ttcaatacat tggttaaaag aggtgattat ttattcataa aacaagtgaa gaaatgatta
       61 aaaataagct ttttcttatg aagtcactga tttattaacg gtgtcattta tggtacaata
      121 tgaacaagca aaaaaagcaa taccccattg ctgttgcttg gtgactgtgg ttgcggcttc
      181 tccgctggca atggaggagg aagtggtgtt cttttaggac gggctagata tgagagtctt
      241 tgttagaagg agggaacatg ttatttattg aattgctgaa ggccatcttc tttggtgtta
      301 ttgagggagt tactgagtgg ctgcctattt ccagtactgg acatctgatt ttggttcagg
      361 aatttatcag acttcatcag gataaggcct ttatggagat gtttaatatt gttattcagc
      421 tgggagcgat tattgcggtt attgttattt actttgaacg cttgaaccct tttcagcctg
      481 gcaagagccc acagcaaatc aggctaacct ggcagctgtg gcttaaggtt gctattgctt
      541 gtattccgtc tattatcatt gcagtaccac ttgatgattg gtttgacgct cattttaatc
      601 atatgcttcc tattgctatt gcattgattg tttatgggat agccttttta tggattgaaa
      661 agagaaatca gacacttgag ccgcgagtcg tcaagctatc tcgtatgtcc tataaaacag
      721 ccttctttat tggctgcttt caggtgctta gcattattcc tgggaccagt cgttcgggag
      781 caacgatttt aggggcgatt attcttggag caagcaggac agttgctgcg gactttacct
      841 tctttttggc cattccgacg atgtttggct atagtggcct aaaagctttg aagtttttta
      901 ttgatggcaa ccatttgacc ctctcgcagc tattagtgct tttagttgcc agcctaacag
      961 cctttgcagt cagtttgtat gtgatcaaat tgttaacaga ttatgttaaa aagcatgatt
     1021 ttacagtctt tgggcggtac cggattgtgt tgggaagctt attgattgtc tacagtgtat
     1081 ttaagtcact tttttagaaa tcgtcaggca gttttcctag gaaggctgct tttacttgct
     1141 gtaaggctag tcataaattg cgaaatcata gtatttctag tataataaaa tgactacgcc
     1201 tgcgaggtat tttacaatgg aaatgaaaca aattagcgag acaacgctaa aaataacaat
     1261 tagtatggac gatttagaag aaagggggat ggagctcaag gacttcttga tccctcaaga
     1321 aaagacagag gagttctttt atgctgtcat ggacgagttg ggccttccgg acaattttaa
     1381 ggacagtggt atgcttagct ttcgagtgac tccaagaaag gatcgcttag atgtttttgt
     1441 gaccaaatca gacctcaata aggaccttaa ttttgaggat ttggcagacc taggtgatat
     1501 ttctcaaatg actccagagg attttttcag aagcttggag cagtctatgc gtgaaaaggg
     1561 tgatgtcaat gcccatgaaa agcttgaaaa aatcgaggag atcatggagg acgtggttga
     1621 tgctaccttg gctgagcaag cagatagtaa ggaagctgct gagcttgatg agccgacaga
     1681 gccacttgat tatgttcact atgttcttga ttttgcttct gttcgagacg ctgtttgctt
     1741 tgctaaggtg attgattttc cgatcgaggc ttctgaattg tataagggtc ctcgtcatta
     1801 tcacatgacg attttacttg atgtgcaaaa caagcctgcc tactttgcca acgtgatgta
     1861 tgccagattg attgagcatg ctagtcctgg aacaaaaaca agagcttatt tgcaggagca
     1921 tggttgtcag ctcatttttg atggtgctgt tgaggagctg caaaaaatca ggttggggta
     1981 gggtatgatg atttcgttca cgatagatga tgtcttggtt ttaattggtg ccttgctgat
     2041 gtcactttta ttaacgccaa ttgtacgttt tctaagcatt agagtcggtg tggtagatac
     2101 tccaaatgct agacggatta ataaggttcc catgccgact agtggaggct tggctatctt
     2161 tacttccttt gtgattgcga gtctggtact gatgcctctg gcatcaaatg gtgctcatat
     2221 tggcgggcaa acctattttc agtatatttt gccagttgtc ttaggaggct tggtggttac
     2281 cataacaggc tttatagacg atgtgtatga gctaagtcct aagctgaaaa tgctgggaat
     2341 tgtcattggt gccattattg tctgggcctt tactgacttt aaatttgata gctttaagat
     2401 tccttttggt ggacccttgc tggcttttga tcctttcttg accttctttt taaccgttct
     2461 ttggattatc tcaattacca atgcgattaa tcttattgat ggcttagatg gtctagtcag
     2521 tggtgtttcg attattagct tagtaacaat ggctattgta gcttatttct ttttgccatt
     2581 gacaaatttc tttttaaccc tgacgatttt aatcctgatt gcatctattg ctggcttttt
     2641 tccctataac tatcacccgg ctattattta tcttggggat acgggagcgc tttttatcgg
     2701 ctttatgatt ggtgtgttat cattgcaggg cttgaaaaat gcaactgcgg tagccgttgt
     2761 tacaccggtt attattttag gtgttccaat tatggatacg attgtggcga ttattcgtcg
     2821 aagcctgtct ggaaagaaat tttacgagcc tgataagatg cacctgcatc accgtctctt
     2881 gtcaatgggg tttacacatc gcggtgcagt gctggttgtt tacggtattg ctatgctctt
     2941 ttccttgatc tctcttttgt tgaatgtctc tagtcgtatt ggtggggtct tgcttatctt
     3001 gggactctta tttgccctag aggtctttat tgaaggtatt gaaatctggg gagaaaaacg
     3061 aacgccccta ttcaacctct tgaagtttat cggtaatagc gattaccgtc agacgacgct
     3121 ttcaaaatgg aagcaaagga aatgatttca gacaagtaaa aagcctgctg aggctttttt
     3181 tgttataatg aagataatga aagcattagg ctattttcag gaaagaagat actgaaagag
     3241 cctaatagaa atgatgaggt atacaatgtc aattcttgaa atcaacaatt tgcatgtttc
     3301 gatagaggat aaagagattt taaagggggt caatctaacc ctaaggacag gtgaaattgc
     3361 tgctatcatg gggccaaatg gaacaggaaa atcaacactg tcagcagcga ttatgggcaa
     3421 tcccaactat caagtgacag agggtgagat tttactagat ggtgtcaata ttctggagct
     3481 agaggttgat gagcgtgcta gactgggact ttttctagcg atgcaatacc cgtctgagat
     3541 tccagggatt accaatgccg aatttatgcg agccgctatg aatgcaggga aagaggacag
     3601 ggataagatt tctgttcgtg acttcattac caagctagat gagaagatgg ccctgcttgg
     3661 catgaaggag gaaatggcag agcgctacct caatgaaggc ttttctggcg gtgagaaaaa
     3721 aagaaatgaa attctgcaat tgctcatgct agagcctaag tttgcgctgt tagatgagat
     3781 tgactcaggg cttgatattg atgccctaaa ggtggtgtca aaaggggtta atgagatgcg
     3841 tggtcaggca tttggtgcga tgattattac ccattaccag cgcttgctta attacatcac
     3901 tccggacttg gtgcatgtca tgatggatgg tcggatagtc ctatcagggg atgctgcact
     3961 tgctatacga ctcgaaaaag aaggctatgc aggcattgct gaggagctag gcattgacta
     4021 taaagaagag gtctaagctg caaggctgtc taaggcttcg ccatagctgt gctgattagt
     4081 atgtttgctg atgattgaaa agcttaccag aaaaaaggaa ggatagatga caaaagaaaa
     4141 gatattggcc ttttctcaag cgcatgctga gcctacttgg ctgcaagagc tgcgcttaaa
     4201 ggcctttgat gtgatgccac atttagagct gcctactatt gaacgggtta aatttcaccg
     4261 ttggaacttt ggtgatggta gcctgacaga aagcactgct ttaggaactg ttccagattt
     4321 tatggccttg ggtgataatc ctaagctggt tcaggtcgga acacagacgg ttcttgagca
     4381 gcttcctatg gaattgatcg aaaagggagt tgtttttaca gaccttgcta cagctctaga
     4441 tgagattccc gagcagcttg aggctcattt tggttctgcc ttagcctttg atgagcatag
     4501 actggcggcc tatcatacgg cttattttaa cagtgcggct gtgctatatg ttccagatca
     4561 tgttgagatt gagcagccaa ttgaagggat cttcttgcaa gatggtgata gtgatgtccc
     4621 ctttaacaag catgtgctca tcattgcagg taaagaaagt aagctgacct accttgagcg
     4681 ctttgagtct ataggagaca agacccaagc agctagtgcc aatattagtg ttgaggtcat
     4741 tgctcaggcg ggaagtcaga ttaagttttc ggcgattgat cgcctgggtg atcaggtgac
     4801 agcctatatc agtcgcagag gccgcttaga tcatgctgcg actattgatt gggcgcttgc
     4861 tctgatgaat gagggcaatg tcattgctga ctttgatagt gatttgatcg gtcaaggctc
     4921 acaggctgat gtgaaggtgg ttgctgcttc aagtggtcgt caagttcagg ggattgatac
     4981 ccgagtaacc aattatggaa aacatacggt tgggcatatt ttacagcatg gggttatctt
     5041 ggagcgcggg acattgacat ttaatgctat cggtcatatc attaagggag caaagggtgc
     5101 tgatgcccaa caagaaagtc gtgtcctaat gctgtcagat caggctcgct ctgatgccaa
     5161 tcctattctc ctgattgatg aaaatgaggt aacagcaggc catgccgcct ctatcggtca
     5221 ggtggatcct gaggacatgt attatttaat gagtagagga ctagaccaag agactgctga
     5281 gcgtcttgtt attcgaggtt ttctaggtgc ggtagtggca gaaatccctg tgccgtcggt
     5341 tcgtcaggat attgttactg ccttagatga taagctggca cgtcgttagt tactagtcaa
     5401 agaaaggagt tatcattgtt tgatcctaat caaatcaaag cagactttaa actacttgac
     5461 caatatgtaa atgatgaggc tcttgtttac ttagataatg cggcgacaac acaaaagcca
     5521 caggcagtgt tagaggccat gcaggcctat tatcaaaagg ataatgccaa tgttcataga
     5581 ggtgtccata ccctggcaga aagagcaaca agacagtatg aggctagtcg tcaaaaggtt
     5641 gctgacttta ttggggctaa gtcaagcaag gaagtgattt tcacaagagg gacgacaagc
     5701 agcttaaatt gggttggaaa atttgctgag caggtcttaa agccaggtga tgaggtgctg
     5761 atttcgatta tggagcacca tgcaaatatc cttccttggc agcaggtttg tcaaaaaaca
     5821 ggggcaaggc ttgtctatgc ttatcttaag aaaggcaagc tagacatgaa tgatctgcaa
     5881 tcaaaattgg gtgctagcac caaatttgtc agtatcaccc atgtctctaa cgtgttaggc
     5941 tgtgttaatc cgattcagga gattgcaagg cttgctcatg ctcggggtgc ctattttgtg
     6001 gttgacgctg cgcagtcagt accgcacatg gctattgatg tgcaggagtt agattgtgat
     6061 ttccttgcct tttcaggcca taagttgctg ggaccgactg gcattggtgt attgtatggc
     6121 aaggaggctc tccttaacca aatgaaccca gttgaatttg gtggcgaaat gattgatttt
     6181 gtttatgagc aggaggcgac ttggaagccc ttgccttgga agcttgaggc aggaaccccc
     6241 catattgctg gtgctattgg tcttggagct gctatttcat atttggaggc tataggaatg
     6301 gatcaggttc atgctcatga ggctgattta gttgcttata ccttgccaag gctgcaggct
     6361 attgctggct tgacggtata tggtcctgac cgatcagatg aacgctcagg cgtccttgcc
     6421 tttaatatag atggcttaca cccgcatgat cttgcaacgg ctttagatta tgagggcgtt
     6481 gcagttagag caggacatca ttgtgctcag cctttgcata agtacttggg actgcattca
     6541 acagttcgtg ctagctttta tctctataat acgagggagg attgcgatcg cttgatagaa
     6601 gctattttaa aagcaaagga gttttttaat ggcactttct aagttaagca gcttatatat
     6661 ggctgttgtg gctgatcatt caagacaccc gcatcatcat ggccagcttg agggtgtaga
     6721 ggcagtccag cttcataatc ctacctgtgg agatgtgatt tcccttacta tcaaatttgc
     6781 tgatgacagg attgaggata ttgcctttgc cggggatggc tgcacgattt cgactgcttc
     6841 gtctagtatg atgacagatg ctgtccttgg aaagacaaag gaagaagcgt tggccctagc
     6901 tgacattttt tcaaatatgg ttcagggaaa tgacgatagc aatcaggctc tcttgggtga
     6961 agctgagcta ttagctgggg ttgccaactt tccacagcgt atcaagtgcg caactctggc
     7021 ttggcatgct ctcaagcagg ctattgaaaa aagcgatgag ttttaagtcc tctctcattt
     7081 agtaacgtat aaaggaaaat agaaaatgtc tgatataaat gaaacagtag ccccccagcc
     7141 aattgattta ggtgattatc aatttggctt tcatgacgat gttgagccta tctactcaac
     7201 aggtaagggc ctaaatgaag cagttgtgag agaattatca gctgctaaag atgaaccaga
     7261 gtggatgctg gaatttcgcc taaaatcact tgaagccttt cataaaatgc ccatgcaaac
     7321 ctggggcgca gacctttcag atattgattt tgatgagatt atctattatc aaaagccatc
     7381 tgataagccg gctcgttcat gggatgatgt tccagataaa atcaaggaaa cctttgagcg
     7441 catcggcatt ccagaggcag agcgagctta tctggcgggc gcctcagcac aatatgagtc
     7501 tgaggtggtt taccacaaca tgaaggctga gtttgaaaag ctgggcatta tctttacgga
     7561 tacggattct gccttaaagg aatatcctga gctatttaag cagtattttg ctaagctggt
     7621 acccccaact gacaacaaat tagccgcctt gaattctgct gtttggtcag gagggacctt
     7681 tatttatgtg ccaaaggggg tcaaggtaga cattcctttg caaacctatt tccgcatcaa
     7741 taatgaacac actggtcagt ttgagcgtac cctaattatt gttgatgagg gcgctagtgt
     7801 gcattatgtg gagggctgta cagcacctac ctattcaagc aacagcttgc acgctgctat
     7861 tgttgaaatc tttgctttag atggtgctta catgcgctat acaacaattc aaaattggtc
     7921 tgacaatgtc tataatttgg tgaccaagcg agcgcgtgct ctcaaggacg caacggttga
     7981 gtggattgat ggtaatctgg gtgctaaaac aaccatgaaa tacccttcag tttaccttga
     8041 tggtccaggt gcgcgtggca ccatgctctc cattgccttt gctaatactg gtcagcatca
     8101 ggatacagga gctaagatgg tgcataatgc gcctcacacc tcatcgtcta ttgtgtcaaa
     8161 atctattgca aaaagtggtg gtaaggttga ctatcgaggt caggttacct ttaacaagct
     8221 gtcaaaaaaa tcagtctctc atatcgaatg tgatacaatc ctgatggacg acatctcaaa
     8281 atcagatact atccccttca atgaaattca caactctcag gtagctcttg agcatgaagc
     8341 aaaagtttca aagatttcag aggagcagct ctattacctg atgagtcggg gactgtcaga
     8401 gagcgaagct actgaaatga ttgtcatggg gtttgttgag ccctttacca aggaattacc
     8461 aatggagtat gctgttgaat tgaatcgctt gatcgcctat gaaatggaag gatcagttgg
     8521 ctagtcaaga agcagctaca ttgaccttat ccattagggt gacctgatgg ataggctttt
     8581 taaaagacat aggtactaac ccaagaggtt agtttttaaa tacctaaggc ataaaaaaga
     8641 cttcttggc
//
LOCUS       DARYXW010000082         8583 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.082, whole genome shotgun sequence.
ACCESSION   DARYXW010000082 DARYXW010000000
VERSION     DARYXW010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8583)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8583
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.082"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            121..255
                     /gene="rpmH"
                     /locus_tag="TV191_001572"
     CDS             121..255
                     /gene="rpmH"
                     /locus_tag="TV191_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEL1508068.1"
                     /translation="MKRTYQPSKIRRQRKHGFRHRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            542..1267
                     /locus_tag="TV191_001573"
                     /pseudo
     CDS             542..1267
                     /locus_tag="TV191_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678571.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
     gene            1286..2599
                     /locus_tag="TV191_001574"
     CDS             1286..2599
                     /locus_tag="TV191_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1508069.1"
                     /translation="MKMKKLASFVMLGASVLGLAACGSSSKEADKSDSAAKTEITWWA
                     FPTFTQEKADDSVGTYEKKIIAAFEKANPDIKVKLETIDFTSGPEKITTAIEAGTAPD
                     VLFDAPGRIIEYGKNGKLADLNDLFTDEFIKDVNNDNIIQASKAGDTAYMYPISSAPF
                     YMALNKKMLKDAGVLDLVKEGWTTDDFEKVLKALKDKGYNPGSFFANGQGGDQGPRAF
                     FANLYSSRITNDDVTKYTTDDANSVKSMEKIASWIKDGLLMNGSQYDGSADIQNFANG
                     QTSFTILWSPAQAGTQAKLLEASKVDYVEVPFPSEDGKPELEYLVNGFAVFNNKDDKK
                     IEASKKFIQFIADDKEWGPKNVVRTGAFPVRSSYGNLYDDERMAMVSKWTQYYSPYYN
                     TIDGFAEMRTLWFPMVQAVSNGDEKPAAALKAFTEKANKTIEKAQ"
     gene            2700..3587
                     /locus_tag="TV191_001575"
     CDS             2700..3587
                     /locus_tag="TV191_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003041053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1508070.1"
                     /translation="MNVNKLKMRETLVSYAFLAPVLVFFVVFVLVPMIMGFVTSFFNY
                     TMTDFTFVGLDNYVRMFQDPVFIKSLINTLIIVVGSVPIVVFFSLFVATKTYNKHVIS
                     RSFYRAVFFLPVVTGSVAVTVVWKWIYDPMSGILNYVLKYGHVIEQNISWLGDKHWAL
                     LAIIVILLTTSVGQPIILYIAAMGNIDNSLVEAARVDGATELQVFWKIKWPSLLPTTL
                     YITVITTINSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFKLSEYGYANTMGVFLAI
                     LISLISFAQFKFLGNDVEY"
     gene            3600..4430
                     /locus_tag="TV191_001576"
     CDS             3600..4430
                     /locus_tag="TV191_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEL1508071.1"
                     /translation="MRKKKLTASDILTTAILCLLTILFIFPFYWIMTGAFKSQPDTIV
                     VPPQWWPKAPTVENFKALIIQNPALKWLWNSIYISVATMLLVCGTSSLAGYALAKKRF
                     YGQRLLFSIFIAAMALPKQVVLVPLVRIVNFMGIHDTLAAVILPLVGWPFGVFLMKQF
                     SENIPTELLESAKIDGCGEIRTFFNVAFPIIKPGFAALAIFTFINTWNDYFMQLVMLT
                     SRDHLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGAVKG
                     "
     gene            4446..4901
                     /locus_tag="TV191_001577"
     CDS             4446..4901
                     /locus_tag="TV191_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEL1508072.1"
                     /translation="MLYDVLENIRRYKGIHRHLDVAIDFLLTRDLRSLTDGKHVILED
                     KVVLFIQHNCLNKEDNALFEYHKRYADLHLLVEGNERVRYGLGYKQEAVSFDEASDIG
                     FVTCERTYDLDLGNDCFCYFFPNEAHQPNGFNDDGDAVTKCLIKVLMED"
     gene            4926..5576
                     /locus_tag="TV191_001578"
     CDS             4926..5576
                     /locus_tag="TV191_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEL1508073.1"
                     /translation="MSSKKRKLMQSIFSLDSKWLRASATIFDLIVLNLLFVLSCLPVV
                     TIGIAKMALYASLRDYRQGDIGSVVGVYGSYLRRFAKRGLQLGILEVLLTSFILVDLY
                     LIQAQVSLFFQLFKISCIAILFVAIMVFLYAYPLAMRYDLPLMSLFQRSFILLSLFFP
                     FSFAFLAVMLLVVFLLQLSPLSLLGGLSLLAIIGISSLTYPYVVIMENLLQKVQLY"
     gene            5605..6525
                     /locus_tag="TV191_001579"
     CDS             5605..6525
                     /locus_tag="TV191_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEL1508074.1"
                     /translation="MKTLTKYQGIIPAFYACYDAEGNISPERVRALTQYYIDKGVQGL
                     YVNGSSGECIYQSVADRKLVLEHVMAVAKGKLTIINHVACNNTKDSIELAQHAEALGV
                     DAIAAIPPIYFRLPEHAVAAYWNAISAAAPNTDFVIYNIPQLAGIALTPSLYQEMLKN
                     ERVIGVKNSSMPVQDIQTFCAIGGDDHLVFNGPDEQFLGGRLMGASAGIGGTYGAMPE
                     LFLRLNQLIKDKDLETAKALQYAINDIIGLLVSAHGNMYGVIKEVLRINERLDIGSVR
                     SPLPELTENDLVICQQAAALIKQTKEQFCS"
     gene            6540..7424
                     /locus_tag="TV191_001580"
     CDS             6540..7424
                     /locus_tag="TV191_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEL1508075.1"
                     /translation="MKRYLAIDIGGTAIKYGLMTETADILEKHEIATEAHKGGPAILD
                     KVKDLVATYQEAGLAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKRVIEETFGIP
                     CDVENDVNCAGLAEAISGSAKDCPVALCLTIGTGIGGCLLIDSQVFHGSSYSACEVGY
                     IHLPDGAFQDLASTTALVRDVARRHGDAVSDWNGRRIFEEAKAGNHHCIAAIDQLVDY
                     LAQGLANICYVANPNAIVLGGGIMAQKDYLQDKILAALNNYLVPSIAEKTQLRFASHE
                     NNAGMIGAYYHFKHKEQV"
     gene            7424..7696
                     /locus_tag="TV191_001581"
                     /pseudo
     CDS             7424..7696
                     /locus_tag="TV191_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514912.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
     gene            complement(7738..8562)
                     /locus_tag="TV191_001582"
     CDS             complement(7738..8562)
                     /locus_tag="TV191_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEL1508076.1"
                     /translation="MIHNHRLISKMEAALDSMTSLEKSIAQFFMETDLKVEELTASDM
                     IKRLHVSQAALTRFAKKCGFTGYREFIFECQKSREAMDQKAPNLQNYNTKKVLMNYRE
                     LIEKATELINEKQLQDIAQWIENAERIYFYGKGSSALAAKEFKLRLMRLGVICEALDD
                     TDSFTWVNSSITDKCLVIGFSLSAQTASVLEALQTAGTRGAKTVLLTTQTDEIPYQLD
                     EIVHIATARHLNYGNRISPQFPMLFVTDIIYAYFLEINKEGKTKIFQETIINPSDK"
BASE COUNT         2331 a         1662 c         2031 g         2559 t
ORIGIN      
        1 aaaggaaaat agagcttgac aggggagttt gattattata gaataatagg gtatgtttag
       61 taactgatat cacaaatagc cggctaaacg aatacgaaaa tctatgagga ggtattcact
      121 gtgaaacgta cttatcaacc aagtaagatc cgtcgtcagc gcaagcatgg cttccgtcac
      181 cgtatgtcaa ctaaaaacgg ccgtcgtgtg cttgctagcc gtcgtcgcaa aggacgcaaa
      241 gtattgtcag cataattgca gaatacatca attaaacaaa tcaggagtgc tcgaggctct
      301 tggtttttta attgttcaaa agtgctaaga gcagcttgat gagtgcttat aaagcaggag
      361 ataggagcca aaaagaggct gcttttttaa ttgctcttcc tgaatacgtt ttcaaaaata
      421 acggaaatag ggctaaaaat gaaagtagtt tctaaaacca gaggaagtat tgaaaacgct
      481 ttaatatctg ctacaataaa gatgtgaacg ttctctaaaa ttaataaaag gagtagaaag
      541 catgcttgaa aaaccaagca aggcagagct actggcagct ctgaaggacg ggctgatcgt
      601 ttcctgtcaa gctctgccgg gcgagcctct ctattcagag gcaggaggta tcatgcctct
      661 gatggtaaag gcagcagagg aagcaggagc agtagggata cgagccaatg gtgttcgaga
      721 tattaaggaa atccaagcgg tgacggatct gccaatcata gggatcatca aaaaggagta
      781 tcctccgcaa gcgcccttta tcacgccaac catggcagag gtagatgcct tagcggcctt
      841 aggtgtagcg gtgatagcct tggattgtac gcaaagggag cgtcatgatg gcttagcgat
      901 agtggatttt attcgagcga taagggagaa gtacccagag cagctgttta tggcagacat
      961 cagtacgctt gaatagggtc tagcagccta tgaggctggt atagattttg tagggacgac
     1021 cttatcaggg tatacgccct atagtcgtca ggggacaggt ccggatatgg agctgataag
     1081 tgccttgtgt gatgcagggg tatcagtgat agctgagggc aagattcata gtccagagga
     1141 ggccagggct gttcaggcct tgggagtagc tggtattgtg gttggtggtg ctattaccag
     1201 accaaaggaa attgcagagc gctttgtggc ggctttgaca tcgtcattgt ctataaaaaa
     1261 taattaatat aaaggagaat ttacaatgaa aatgaagaaa ttagcttcat ttgtgatgct
     1321 tggagcatct gttttagggt tagcagcctg tggcagtagc agcaaggagg ctgacaaatc
     1381 agattcagct gctaagacag agatcacctg gtgggccttt ccaaccttca ctcaagaaaa
     1441 ggctgatgat agcgtaggaa cctacgaaaa gaaaattatt gcagcctttg aaaaggccaa
     1501 tccagatatt aaggtcaagc tagaaaccat tgatttcacc tctggtccag aaaaaatcac
     1561 tactgcgatt gaggcaggta cagcaccaga tgtgctcttt gatgctccag gtcgtatcat
     1621 tgagtatggt aaaaacggta aattagctga cttaaatgac ctgtttactg atgagtttat
     1681 caaggacgtc aacaacgata acattatcca agcctctaaa gcaggagata cagcttatat
     1741 gtatcctatc agctcagcgc cgttttatat ggccttaaat aaaaaaatgc tcaaggacgc
     1801 tggtgttctt gaccttgtca aagagggctg gacaaccgat gattttgaaa aggtcttaaa
     1861 agccttaaag gataagggct acaatcctgg gtcattcttt gccaatggtc agggtggtga
     1921 ccaaggtcct cgtgccttct ttgccaacct ctatagcagc cgcatcacaa atgacgatgt
     1981 gactaagtac accactgatg atgctaattc tgtcaagagc atggagaaaa tcgcaagctg
     2041 gattaaggat ggccttctaa tgaatggctc tcaatatgat ggctcagctg atattcaaaa
     2101 ctttgctaat ggtcaaacct catttacaat cctatggtca ccagcgcaag caggaacaca
     2161 ggctaagctg ttggaagcaa gtaaggttga ttatgttgag gttccattcc catcagagga
     2221 cggcaagcct gaattagaat acctagtgaa cggctttgca gtgttcaaca acaaggacga
     2281 caaaaagatt gaagcttcta agaaatttat ccagtttatc gcagatgaca aagaatgggg
     2341 tccaaaaaat gtggttcgta caggtgcatt ccctgtaaga agctcttatg gtaatctcta
     2401 tgatgatgaa cgcatggcaa tggtttctaa gtggacacaa tactattcac catactacaa
     2461 cactattgat ggctttgctg agatgagaac actatggttc ccaatggttc aggcagtatc
     2521 aaatggagat gaaaagcctg cagcagccct caaagcattc actgaaaaag caaataaaac
     2581 catcgaaaaa gcacaatagt gtgagataaa agtggctcct tttcaatgca catgtccaat
     2641 ggtcactggt aaggagcctt tccttttagg aagattaata gaaaaagagg tatctttgag
     2701 tgaacgtcaa taagttaaaa atgagagaga cactcgtttc atatgctttt ttggccccgg
     2761 tcttggtttt ctttgtggta tttgttttag taccaatgat tatgggcttt gttactagct
     2821 tttttaatta tacgatgaca gactttacct ttgtcgggct tgataactat gtgagaatgt
     2881 ttcaggatcc tgtgtttata aagtctttga ttaataccct tattattgta gttggttcag
     2941 taccaattgt tgttttcttt tcattatttg tagcgacaaa aacctacaat aagcatgtga
     3001 tttcacgttc gttttaccgg gcggttttct tcctgccagt tgtgacaggt agtgttgcgg
     3061 taacagttgt ttggaaatgg atctatgatc ctatgtcagg tattttgaac tatgtgctaa
     3121 agtatgggca tgttattgag caaaatatta gctggcttgg ggacaagcat tgggccttgc
     3181 tggctattat tgtgatttta ttaacaacct ctgttgggca gcctattatt ctttatattg
     3241 ctgcgatggg aaatattgac aattccttag tggaggcagc tcgtgttgac ggtgcgactg
     3301 aattgcaggt cttttggaaa ataaaatggc caagtctatt gccaaccact ctctatatca
     3361 cggtcatcac aacgatcaat tctttccaat gctttgcctt gattcagctg ttgacctctg
     3421 gtggtccaaa ctattcaacc agcaccctga tgtactatct ttacgaaaaa gccttcaagc
     3481 tatcggaata cggctatgct aacacgatgg gggttttctt ggctatcttg atttcactga
     3541 tcagctttgc ccaattcaaa ttcttgggta atgatgtgga atattaaaag gagcttgaca
     3601 tgaggaaaaa gaaattaaca gcatcagata tcctaacaac agccattcta tgtttattaa
     3661 caatattatt tattttcccc ttttattgga tcatgacagg agcctttaaa tcccagccgg
     3721 atactattgt tgtcccacca caatggtggc caaaggcacc tactgttgaa aattttaagg
     3781 ccttgattat tcaaaatccg gctcttaaat ggctctggaa cagtatctat atttctgttg
     3841 ccaccatgct tttggtttgt ggcacctctt ccttggcagg ctatgcttta gcaaaaaaac
     3901 ggttttatgg gcaacgtttg ttgttttcaa tctttattgc tgctatggct ctgcctaagc
     3961 aggtcgtctt ggtgccattg gttcgtattg tgaattttat gggcatccac gatacgctag
     4021 cagcagttat tttgcctttg gtgggctggc cttttggggt attcctgatg aagcaatttt
     4081 cagaaaacat accaacagag ctgctggagt ctgccaaaat tgatggctgt ggtgagatta
     4141 gaaccttctt taacgttgct tttccaatca ttaagccagg ttttgctgcc ttagcgatct
     4201 ttacctttat taatacctgg aatgactact ttatgcagct agtaatgcta acatcaagag
     4261 atcatttgac aatatccttg ggggtagcca ctatgcaggc tgagatggca acaaactatg
     4321 gtttgatcat ggctggtgca gctcttgccg cagttccgat tgttacagtc tttcttgtgt
     4381 tccaaaaatc ctttacccaa ggtatcacca tgggagctgt caaaggttag aaaggtcagg
     4441 agattatgct ctatgatgtc ttggaaaaca ttcgtcgcta caagggtatc catcggcatt
     4501 tagatgtggc cattgacttt ttattgacaa gagatttaag gtcactcaca gatggcaagc
     4561 atgtgatttt agaggataag gtggttctct ttattcagca taattgtctc aataaagagg
     4621 ataatgcctt gtttgaatac cataagcgct atgccgattt gcatctacta gtcgagggga
     4681 atgagcgagt acgctatggc ttaggctaca agcaggaggc tgttagcttt gatgaggcat
     4741 cagacatcgg ctttgtgacc tgcgagagga cttatgactt ggacttggga aatgattgtt
     4801 tttgctattt ctttcccaat gaagctcatc agcctaatgg ctttaacgac gatggtgatg
     4861 cggtcacaaa atgcttgatt aaggtgttga tggaagatta actagaaagg atagggagta
     4921 atgatatgag cagcaaaaaa agaaagctaa tgcagtccat ttttagcttg gatagcaaat
     4981 ggctgagggc tagtgctact atctttgacc ttatcgtgct caatttgctt tttgtgctgt
     5041 cttgcttgcc tgtggtaacg attggcattg ccaaaatggc cttgtatgct agtctgcgag
     5101 attaccggca aggggatatc ggctctgttg taggcgtcta cggctcttat ctacggcggt
     5161 ttgccaagag aggccttcaa ttagggatcc tagaagtgct cttgacgagc tttatcttgg
     5221 ttgaccttta tctcattcag gctcaggtgt cgcttttctt tcaactattt aagattagct
     5281 gtatagcgat attatttgtg gctattatgg tctttttgta tgcttatcct ttagctatgc
     5341 gatatgattt gcctcttatg tcattatttc agcgaagctt tatcttgctt agtcttttct
     5401 tcccctttag ctttgctttt ttagctgtta tgctgctagt ggtctttttg ctgcagctat
     5461 ctccgctaag tctattagga gggctgtcgc ttttagccat tattggcatt agcagcctaa
     5521 cctatcctta tgtcgtcatt atggaaaacc ttcttcaaaa ggtacaactt tattaaaaat
     5581 aagatttaga aaaagagtgt cattatgaaa actttaacca aatatcaagg gattatccct
     5641 gccttttatg cctgctacga tgctgagggc aacatcagtc cagagcgtgt tcgtgctttg
     5701 acacaatatt atattgataa gggtgtccaa gggctttatg tcaatggctc atcaggcgag
     5761 tgcatttacc aaagcgttgc agaccgtaag ttggtcttag agcatgtgat ggcagtagcc
     5821 aagggcaagc taaccattat caatcacgtt gcctgcaaca ataccaagga cagcattgag
     5881 ctggctcagc atgctgaggc cttgggggtt gacgctattg cagcgattcc accgatttat
     5941 ttccgtttgc cagagcatgc tgtggctgct tactggaatg caatttcagc tgctgctcca
     6001 aatactgatt ttgtgattta caatattcct caattggctg gtattgcctt gaccccaagc
     6061 ctctatcagg aaatgctcaa aaatgagcgt gtcataggtg tcaaaaactc ctccatgcct
     6121 gttcaggata ttcaaacatt ttgtgctatc ggaggtgatg atcaccttgt ctttaatgga
     6181 ccggacgagc aatttttagg gggtcgtctc atgggggcct ccgctggaat tggcggtacc
     6241 tatggagcga tgccagagct tttcttacgc ttaaatcaat tgatcaagga caaggaccta
     6301 gagactgcta aggccttgca gtacgctatc aatgatatta ttgggttatt ggtttctgcc
     6361 catggcaata tgtatggtgt tatcaaggaa gtgctgcgca ttaatgagag gctggatatt
     6421 ggctctgttc gttctccttt gccagagtta accgaaaatg atttggtgat ctgtcagcag
     6481 gctgcagcct tgattaagca gaccaaggaa caattttgct cttaaaatga ggtgatcaaa
     6541 tgaagcgtta tcttgctatt gatattggcg gtacagccat caaatatggc cttatgacag
     6601 agacagcaga catactggaa aagcatgaaa tcgccactga ggctcataag ggcggtcctg
     6661 ctattttaga caaggtcaag gacctggttg cgacctatca ggaggctgga ctagctggtg
     6721 ttgcgatttc ttcagctggc atggtggatc ctgataaggg cgaaatcttt tacgcagggc
     6781 cacaaattcc gaactacgca ggcacgcagt ttaaaagggt gattgaagaa acctttggta
     6841 ttccctgtga tgttgaaaat gatgtcaatt gtgccggtct agcagaggct atttctggca
     6901 gtgctaagga ttgccctgta gccctttgct taaccatcgg tacaggaatt ggcggctgcc
     6961 tgctgattga ttcgcaggtt tttcatggca gcagctactc tgcctgtgag gtaggctata
     7021 tccatttgcc ggacggtgcg tttcaggatt tggcctccac aacagctctt gttagagatg
     7081 ttgctagacg tcatggagat gctgttagcg attggaatgg tcgtcgtatt tttgaagagg
     7141 ctaaggcagg taaccaccat tgtatagcag ccattgacca gttagttgac tatctagctc
     7201 aagggcttgc caatatctgc tatgttgcta atccaaatgc tattgtctta ggcggtggca
     7261 ttatggctca aaaggactat ttgcaggata aaatcctagc tgccctcaat aattatctgg
     7321 tacctagcat cgcagaaaaa acccagcttc gatttgccag ccatgaaaac aatgctggta
     7381 tgattggggc ttactaccat ttcaagcata aggagcaagt ctaatgatag aaaccatgtc
     7441 acttgaagag atgatgtcct acagggggcg tcacgaggtg cccaaggatt ttgatcattt
     7501 ttgggagacc tgtatcaagg aaaatcaagc tgcctcttat cagcttgatc aaaaggattt
     7561 tggccttgat tttgctgatt gctatgagtt gcgcttcaaa gggagtaatg gctcaacgat
     7621 ctatgccaaa tgtgtctttc caaaagccaa gcagctagtc ccagttgtct tttattttca
     7681 tggctaccag ggtcagtaca cagctagcta gggtcattga ggtgcttttt tgtgatgcta
     7741 tttatctgaa ggattgataa tcgtctcttg gaaaattttt gttttgcctt ccttgttgat
     7801 ttctaaaaaa taagcgtaga taatatccgt tacaaagagc attggaaatt gtggggagat
     7861 acgattgcca tagttaaggt gacgagcagt agcgatatgc acaatttcgt caagctggta
     7921 agggatttca tcggtctggg ttgtgagcag cactgtcttg gcaccgcgtg tcccagcggt
     7981 ctgcaaagcc tctaagacgg acgctgtttg agcagagagc gaaaaaccaa taaccaagca
     8041 tttgtctgta atgctgctgt taacccaggt gaagctatca gtgtcatcta aggcctcgca
     8101 aataacacca agtcgcatca gacggagctt gaattctttg gcggcaagag ctgagctgcc
     8161 cttaccgtaa aaataaatcc gctcagcatt ttcaatccat tgcgcaatgt cttgtagctg
     8221 cttttcattg atcagctcgg tagccttttc gatcaattca cggtagttca taaggacctt
     8281 tttagtgttg taattttgca ggttgggtgc cttttgatcc attgcctcgc gacttttttg
     8341 gcattcaaag ataaattcgc gataaccggt aaagccacat tttttggcaa agcgtgtcaa
     8401 ggctgcctgt gagacatgaa gccttttaat catgtctgaa gctgttagct cttcgacctt
     8461 taggtctgtt tccataaaaa attgagcgat gcttttttct aagctcgtca tgctgtctag
     8521 tgcagcttcc attttgctga ttaaacggtg attgtgtatc atatgaactc cctgatgtaa
     8581 ggc
//
LOCUS       DARYXW010000083         8435 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.083, whole genome shotgun sequence.
ACCESSION   DARYXW010000083 DARYXW010000000
VERSION     DARYXW010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8435)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8435)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8435
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.083"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(3..1337)
                     /gene="trmFO"
                     /locus_tag="TV191_001583"
     CDS             complement(3..1337)
                     /gene="trmFO"
                     /locus_tag="TV191_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEL1508077.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKATPQHK
                     TTHFAELVCSNSFRGDSLTNAVGLLKEELRRLDSIIMRAGEAHRVPAGGAMAVDREGY
                     AKAVTAELENHPLIEIIREEVIDIPSDAITVIATGPLTSDSLAEKIHALNGGAGFYFY
                     DAAAPIVDKSTINMDRVYLKSRYDKGEAAYLNCPMTKEEFMAFHEALTTAEEAPLNAF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYKGPRDGDFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLEHAEFVRYGVMHRNSYMDSPKLLTQG
                     FQSRANHRLFFAGQMTGVEGYVESAASGLVAGINAARLFKEEEPLVFPNTTAIGSLPY
                     YITHADSKHFQPMNVNFGIIKELDGPRIRDKKERYEAIAKRALADLAAYLTV"
     gene            complement(1719..2432)
                     /locus_tag="TV191_001584"
     CDS             complement(1719..2432)
                     /locus_tag="TV191_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3307 domain-containing protein"
                     /protein_id="HEL1508078.1"
                     /translation="MQGLSDYLYQHPILVLLVICHFLSDYHLQSQVIADKKEEQLAYL
                     GLHLLGVAAPLFLVVMCIPKLWLTAILIFSSHAVIDYFKPKWARIIKLDRSWVFVLDQ
                     LLHLFIILALVARVNQAEIPDWLHARQLLLVLFMVLITKPVNIIFKLCFNKFQPASDK
                     PMDTIVGAGAAIGNLERIVMGVCMVLGQFASIGLVLTAKSIARYNKISESPAFAEYYL
                     IGSLFSVLSVFIAAWMCFF"
     gene            complement(2453..3100)
                     /locus_tag="TV191_001585"
     CDS             complement(2453..3100)
                     /locus_tag="TV191_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1508079.1"
                     /translation="MLYIAVIGDLVHSKQIQSRSLVQESLKACLDQLNHDFSSYIVSN
                     LSVTLGDEFQGLLTNDAPVFQLIDLINQAMTGYPVRFGIGQGTILTDINPDISIGADG
                     PAYWRAREAIHYIHQKNDYGNTQVAIRTDKEHKDLVLNSLLAAGEAIKASWRASQLEV
                     FHALLDLGIYEEQFDQQLIGDTLDLQSSALSKRLKSSSVKVYLRSRHAALTYLQE"
     gene            complement(3215..5347)
                     /gene="topA"
                     /locus_tag="TV191_001586"
     CDS             complement(3215..5347)
                     /gene="topA"
                     /locus_tag="TV191_001586"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEL1508080.1"
                     /translation="MVTKTATKSKQETKRSATKKKSAAAKKNLVIVESPAKAKTIEKY
                     LGRQYKVVASVGHIRDLKKSSMSIDFDNHYEPQYINIRGKGPLINALKKEAKNAKKVY
                     LASDPDREGEAISWHLSHILGLDPDDNNRVVFNEITKDAVKEAFEGPRKIDMDLVDSQ
                     QARRVLDRIVGYSISPILWKKVKKGLSAGRVQSVALKLIIDREHEIKAFVPEEYWSID
                     GLFKKGTKKFQASFYGLNGKKMKLNTNDDVKLVLSRLSSDDFMVSKVEKKERRRHAPL
                     PYTTSSLQQDAANKINFRTRKTMMVAQQLYEGISLGPNGTQGLITYMRTDSTRISPVA
                     QNDAAGFIVERFGSQYSKHGNRVKNATGAQDAHEAIRPSNVNHTPEAIAKFLDKDQLK
                     LYTLIWNRFVASQMTAAVFDTVKVNLEQNSVLFVANGSQMKFDGYMAVYNDSDKSKML
                     PEMTEGEVVKKVTLTPEQHFTQPPARYSEASLIKTLEENGVGRPSTYAPTLDVIQRRY
                     YVKLAAKRFEPTELGEIVNQLIVEFFPDIVDVKFTADMEDKLDQIEIGKEAWQNVIDQ
                     FYKPFVKELTKAETEIEKIQIKDEPAGFDCELCGHPMVVKLGRFGKFYACSNFPECHH
                     TKAITKEIGVSCPACQQGQVIERKTKRNRIFYGCDRYPECDFTSWDLPVGRSCPKSGD
                     YLVEKKIRGGKQVVCSNEVCDYKEEIVK"
     gene            complement(5448..6293)
                     /gene="dprA"
                     /locus_tag="TV191_001587"
     CDS             complement(5448..6293)
                     /gene="dprA"
                     /locus_tag="TV191_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEL1508081.1"
                     /translation="MNNFELYKLKKAGLTNLNILNLIDYQQRNNKSLSLRDMAVVSCC
                     KNPVLFIETYKQLNVALLKKEFNQFPSLSILDKQYPLALREIYNPPVLLFYQGDLSLL
                     EKPKLAVVGSRESSEIGTRSVYKIIKELKNHFVIVSGLARGIDTSAHLACLKAGGQTI
                     AVIGTGLDRYYPKENHQLQEFLSQRHLVLSEYGAGEAALSYHFPERNRIIAGLSRGVL
                     VVEAKQRSGSLITCQLAMEEGRDIFVVPDNILNGTSAGCLKLIKDGASCVTHGRDILS
                     EYHYS"
     gene            complement(6539..7321)
                     /locus_tag="TV191_001588"
     CDS             complement(6539..7321)
                     /locus_tag="TV191_001588"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEL1508082.1"
                     /translation="MTAMTIKDIKARLEAVSSLSDPFFEELKADKRLGVQKAVSSRKR
                     ALEAILKEEARLEAMLTYEQALYQKGFQAIAGIDEVGRGPLAGPVVAACVILPKGCTI
                     KGLNDSKKIPKAKHEAIYQAIQKKALGIGLGIIDNHTIDRVNIYEATKLAMTAAINQL
                     EGSVSKPDYLLIDAMTLEVSIPQQAIIKGDASSMSIAAASIVAKVTRDRLMLDYDKAF
                     PGYGFAKNAGYGTKEHLQGLHQYGVTPIHRQSFEPIKSMILR"
     gene            complement(7302..8156)
                     /gene="ylqF"
                     /locus_tag="TV191_001589"
     CDS             complement(7302..8156)
                     /gene="ylqF"
                     /locus_tag="TV191_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEL1508083.1"
                     /translation="MATIQWFPGHMSKARRQVQENIKHVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLMLLNKADLADNTHTKKWQQYYEKQGIKTLAINAKEQATVKRVTEAAK
                     ELMADKLRRLRERGIQKETLRTMIIGIPNAGKSTLMNRLAGKKIATVGNKPGVTKGQQ
                     WLKSNKELEILDTPGILWPKFEDELVGLKLALTGAIKDQLLPMDEVTIFGLNYFKKYY
                     PNRLLKRFKAIDLEADAPEIIMSLTRQLGFKEDYDRFYSLFIKDIRDGRLGQYTLDQV
                     GDDDSNDY"
BASE COUNT         2468 a         1957 c         1558 g         2452 t
ORIGIN      
        1 gattataccg ttaaataagc tgccagatca gctaaggcac gtttagcgat agcttcatag
       61 cgttcctttt tatctctgat acgaggtccg tcaagctctt taataatacc aaaattgaca
      121 ttcattggtt gaaaatgctt gctgtccgcg tgtgtaatat aataaggcag gctgccaatt
      181 gctgttgtat ttggaaaaac aagtggctct tcttccttga atagccgagc agcattaatg
      241 ccagccacaa gtccagaagc tgctgactcg acatagccct ccacaccggt catctgacct
      301 gcaaagaaaa gcctgtgatt agcgcgtgat tggaagcctt gtgtcagaag ctttggtgaa
      361 tccatatagg aattacggtg catcacaccg taacgcacaa actcagcatg ctcaaggcct
      421 ggaatcattt ggaaaacccg cttttgctct ccccatttta aatgtgtctg aaagcccacg
      481 atattataaa ggctgcctgc agcattatcc tgacgcagct gcacaacagc atagggcgtc
      541 ttgaaatcac cgtcacgtgg tcccttgtaa tcatctggat attccaagcc aaccggcttc
      601 attggaccat aaagcatagt cttaatccca cgctttgcca taacctcaat tggcatacag
      661 ccttcaaaat acttttcctt ttcaaaagca tttaaaggag cttcctctgc tgttgtcaaa
      721 gcctcgtgaa aggccataaa ctcttccttg gtcattggac agttcagata agcagcttct
      781 cccttatcat atcgcgattt taaataaacc ctatccatgt taatggttga cttatcgaca
      841 attggagctg ctgcgtcgta aaaataaaag ccagcaccac catttaaggc atgtattttt
      901 tcagcaaggc tgtcactggt caaggggcca gttgcaatta ctgtaatagc atcgctagga
      961 atgtcaataa cctcctcacg aatgatttca atcagagggt gattttcaag ctcagctgta
     1021 acagccttgg catagccttc gcgatctaca gccattgctc ctccggcagg gacacgatgg
     1081 gcttcgccag cacgcataat aatcgaatcc agacgacgca gctcttcctt taaaagccct
     1141 actgcgttgg ttaagctgtc accacgaaaa gagttggagc aaaccaattc tgcaaaatgg
     1201 gtggttttgt gttgcggtgt tgccttgaca ccacgcatct catatagctt aacaggaata
     1261 ccacgcttag caatttgata agctgcctct gatccagcta gaccagcacc aataacatta
     1321 atataagatt gagacaatag accaatacct ctttggggac ttatccatca ctgattgccc
     1381 cgcaactctt tctttcaagt aattaccctg cctattataa cagaaataag agcaaagcaa
     1441 aagaaggagc tgaacagcct cagtctttta tataaaggag ataagcccgt acctgcacgc
     1501 tctccacaaa gctagctgct tcaagcattt tagctttcgc ccaataccag ctatccacat
     1561 atcttgttca ctgcagtagt tactggaagg ctttttaagg cttatttttc aaaatctagc
     1621 caaaaatatt tcaccggacc tcatcatctt gctggtagca gctaaacaag ccttttccag
     1681 taaaaaaaaa gcaagcgaaa gcctgccctt gttcttgttt agaaaaaaca catccatgct
     1741 gcgataaaga cacttaagac actaaacagc gatccaatca aataatattc agcaaaggct
     1801 gggctttcag agattttatt gtagcgagca atagacttag cggtaagcac cagtccgatt
     1861 gaagcaaatt gtcccaacac catacaaacg cccataacaa tacgctctaa attaccaata
     1921 gccgcacccg cccctacaat ggtatccatt ggtttatcac tagctggctg gaatttattg
     1981 aagcagagct taaagataat attgacaggc ttggtgatca aaaccataaa aagcactaac
     2041 aataactgcc gagcatgtaa ccaatcaggg atctcagcct gattaacacg agcgactaaa
     2101 gccagaataa tgaaaagatg caagagctgg tccaacacaa agacccacga ccgatcaagc
     2161 ttaatgatac gagcccattt tggcttaaaa taatcaataa ccgcatggct actaaaaata
     2221 aggatcgctg ttagccaaag cttaggtata cacatcacca ctagaaacaa tggagcagct
     2281 acccctaata agtgcagccc cagataagca agctgctcct ccttcttatc agcaataacc
     2341 tgactctgaa ggtgataatc tgataaaaaa tgacaaatca ctagcagcac taaaatagga
     2401 tgctgataaa ggtaatcaga taagccctgc ataggtggct cctttcctct ttttattctt
     2461 gtaggtaggt caaagctgca tggcgacttc taagataaac ctttacactg ctgcttttta
     2521 agcgctttga caaggcactt gattggaggt ccaatgtatc gccaatgagc tgttggtcaa
     2581 attgttcttc atagatccct aagtctaaaa gcgcatgaaa cacctctaat tgactagcac
     2641 gccagctagc ttttatcgcc tcaccagctg ctaaaaggct attgagcacc agatccttgt
     2701 gctccttatc agtccgtata gctacctggg tattgccata atcatttttt tgatgaatgt
     2761 aatgaatagc ctctctggca cgccaatagg ctggaccgtc agcaccaata ctaatatcag
     2821 ggttaatatc agtcaaaata gtcccctgtc caataccaaa cctaacaggg tagcctgtca
     2881 tggcttgatt aattaaatca atgagttgaa aaacaggcgc atcattagtc aacaagcctt
     2941 gaaattcatc acccagagtc acagataagt tagagacgat ataggaagaa aaatcatggt
     3001 tgagctgatc cagacaggcc tttaaggact cttgcaccaa agaacgcgac tgaatttgct
     3061 tagaatggac caaatcccca ataacagcga tatatagcat gattttccct ccttttatga
     3121 cttccattat aacagacaaa aaccaaaaag tccattataa tggaaaatca tctatatttc
     3181 cgttataatg gacctctgct aaaatagttc aaacctactt tacaatctct tctttatagt
     3241 cacagacttc attgctacac acaacctgct tacctccacg aatttttttc tcaacaaggt
     3301 aatcgcctga cttcggacaa gaccgtccta ccggcaaatc ccacgaggta aagtcacact
     3361 cagggtagcg gtcgcagcca tagaaaatac ggttacgctt tgttttgcgc tcaatgactt
     3421 ggccttgctg acaagctgga caagaaactc caatttcctt tgtgatggcc tttgtatgat
     3481 ggcactcagg aaagttacta caagcataaa acttgccaaa tctacccagc ttaacaacca
     3541 tcgggtggcc gcacagctca caatcaaaac cagccggctc gtccttgatt tgaatttttt
     3601 cgatctccgt ttcagccttg gttaactcct taacaaatgg cttgtagaat tggtcaatca
     3661 cattctgcca ggcttctttg ccgatctcta tctgatcaag cttatcttcc atatcagctg
     3721 taaatttgac atcaacaata tcagggaaga attccacaat caattgatta acaatttcgc
     3781 ctaattccgt cggctcaaag cgtttagcag ccagcttaac ataataacga cgctgaatca
     3841 catcgagtgt tggagcatag gttgatggcc ttccaacacc gttttcttcc agtgttttaa
     3901 tcaggcttgc ttctgaataa cgagctggcg gttgagtaaa gtgctgttca ggtgttaagg
     3961 taaccttttt aaccacttct ccttctgtca tttcaggaag catcttgctt ttatcagaat
     4021 cattgtaaac agccatataa ccgtcaaatt tcatctgact gccattggca acaaaaagga
     4081 cactattttg ctctaggtta accttaacag tatcaaacac agcagctgtc atctgactag
     4141 cgacaaagcg gttccaaatc aaggtataga gctttagctg atccttatct aaaaatttag
     4201 caatagcctc tggcgtatgg ttcacattag atggtcgaat agcctcatga gcgtcttgag
     4261 caccagtagc atttttaact cgattgccat gcttagagta ctgactaccg aaacgttcaa
     4321 caataaagcc tgcggcatca ttttgagcaa ctgggctgat acgagtagag tccgtacgca
     4381 tgtaagtaat taacccttgt gttccattag gaccaagact aatcccctca taaagctgct
     4441 gagcaaccat cattgtttta cgagtccgaa agttaatctt attggctgcg tcctgctgca
     4501 atgaggaggt tgtataaggt aaaggagcat gacgcctgcg ttcttttttc tcaaccttac
     4561 taaccataaa atcatcgcta cttaatcgag acaaaacaag cttaacatca tcattggtat
     4621 tgagcttcat ctttttgcca ttgaggccgt aaaagcttgc ttggaatttt tttgtccctt
     4681 ttttaaagag accatcaatt gaccaatatt cttcaggaac aaaggcctta atctcatgct
     4741 ctctgtcaat gattagcttt agagcaaccg attgcacgcg ccctgctgaa agcccctttt
     4801 taaccttttt ccagagaatt ggcgaaatgg aataaccaac aatacgatcc agtacacgac
     4861 gtgcctgctg tgagtcaacc aaatccatat caatttttct tgggccttca aaagcttctt
     4921 tgacggcatc ctttgtgatt tcattgaaaa cgacacgatt gttatcatca ggatcaagtc
     4981 ccaaaatatg tgataaatgc catgaaatgg cctctccctc acgatccggg tcacttgcta
     5041 gataaacctt tttagcattc tttgcttctt tttttaaggc attaatcagc ggacccttac
     5101 cacgaatatt aatatactgt ggctcataat gattgtcaaa atcaatagac attgatgatt
     5161 ttttcaaatc acgaatatga ccaaccgagg caacgacctt atactgacgt cccaaatatt
     5221 tttcgatggt tttagcctta gcaggtgatt caacaatgac tagatttttt ttagcagctg
     5281 ctgatttttt ctttgtagca gatcttttcg tctcttgttt tgacttagtt gctgtttttg
     5341 ttaccaattg acacacttcc tataacagtt atggttaaag cttctagcat aatatcccat
     5401 tttttaagaa ctgtcaacaa aaaattttct ataaatagga agaaaagtta agaatagtgg
     5461 tattctgaaa gaatgtctct gccatgagtg acacagctgg caccatcttt gatcagcttc
     5521 aaacagcccg ccgatgtccc attaagaata ttgtcaggta cgacaaaaat atcacgtccc
     5581 tcttccatag ctagctgaca ggtaatcaaa gagccagagc gctgcttagc ctcaacaaca
     5641 aggacacctc gactaagacc tgcgataata cggtttcttt cagggaaatg ataagacaag
     5701 gcggcctctc cagccccata ttcactgagc acgagatgac gctgagataa aaactcctgt
     5761 agctggtgat tttcctttgg atagtagcga tctaggccag tcccgataac agctatggtt
     5821 tgcccacctg ctttcaagca agcgagatga gcactggtat caatacctct agcaagcccg
     5881 ctgacaatga caaagtgatt cttaagctct ttgatgattt tgtaaacaga ccgcgtccca
     5941 atttcactgg attctctaga gccaacgact gccagcttag gcttttctaa caggcttaaa
     6001 tcaccttgat aaaagagtaa aacaggagga ttatagattt ccctcagggc caatgggtat
     6061 tgcttatcta ggatagataa gctcggaaac tggttgaatt ccttttttaa caaggcgaca
     6121 tttaattgct tgtaggtctc aataaataaa actggatttt tgcagcaaga aaccactgcc
     6181 atatctctaa gggatagaga cttgttatta cgctgctggt agtcaatcag gttaagaata
     6241 tttaaattag ttagcccagc cttttttaat ttataaagtt caaaattatt catcactgta
     6301 cctctctaat gatttattcg taaaaaaatt aaaaaagctc tgactaaaca aagctttttg
     6361 caaactcttg aggagctgta caggattcca gcaaaaaaat cgaggcctcc tagcctttgt
     6421 atgagcattg tagggcagct catcacatag cattccattg aaaaatacca gaattgtaga
     6481 tccacctagt ggctatcgtt tttgctttcg gcagctacct tttctcaaaa tgagattttt
     6541 agcgtaagat cattgatttt atcggctcaa agctttgccg atgaattggt gtgacaccat
     6601 actggtgcaa tccctgcagg tgctccttgg tcccatagcc ggcattttta gcaaagccat
     6661 agcctggaaa ggccttatcg taatcaagca tcaatcgatc tctggtaacc ttagccacaa
     6721 tagaggctgc agcgattgac atagagctcg catcgccttt tataatagcc tgttgaggaa
     6781 tagaaacctc tagtgtcatg gcatcaatga gcaggtaatc aggcttactc acagagccct
     6841 ccagctgatt aatggcagct gtcattgcta attttgttgc ttcatagata ttaacccggt
     6901 caatggtatg gttgtcaata attccaagac cgattcccaa cgctttcttt tgaatggctt
     6961 ggtaaattgc ttcatgctta gctttaggaa tttttttaga atcatttagc cccttaatgg
     7021 tgcagccctt tggcagtata acacaggctg ctacaactgg tccagccaga ggacctcgac
     7081 caacctcatc tataccagca atcgcttgaa agcctttttg gtaaagcgcc tgttcatacg
     7141 tcaacatcgc ctcaagccgg gcttcctctt ttaagatagc ctctaaagcc ctttttctgc
     7201 tagatacagc cttttgaacg ccaagccgct tatccgcctt tagctcttca aaaaatggat
     7261 cagaaagact agaaacagct tctagacgag ctttaatgtc tttaatagtc attgctgtca
     7321 tcatcaccaa cctgatctaa ggtgtactga ccaagtcttc catcacgaat atccttgatg
     7381 aataagctgt aaaaacgatc atagtcttcc ttaaagccaa gctgacgtgt caaggacatg
     7441 atgatttctg gagcgtcagc ctctagatca atagccttaa aacgctttaa taggcgatta
     7501 ggataatact tcttaaaata attcaatcca aaaatcgtga cctcgtccat tggcaacagc
     7561 tgatccttaa tagcccctgt cagggctaat tttaacccaa ccaattcgtc ttcaaacttt
     7621 ggccataaga tacccggagt atccaatatc tctagttctt tattggattt tagccattgc
     7681 tgtcccttgg tcactcctgg cttattgcct actgtggcaa ttttttttcc cgccaagcga
     7741 ttcatcaggg ttgatttgcc agcatttgga atgccaataa tcatggttcg tagcgtttct
     7801 ttttgaatgc ctcgttctct taagcgacgt agtttatctg ccatcaattc cttagcagcc
     7861 tcggtgaccc ttttgaccgt agcctgttcc ttagcattga tagctaatgt cttaatccct
     7921 tgcttctcat aatattgttg ccatttctta gtatgcgtgt tatctgctag atcagcctta
     7981 ttaagaagca ttagcttggg cttatctcca acaattttgg tcagcatagg attttgactt
     8041 gataaaggta gcctagcgtc tactaaaatc gtcacaaaat caacatgctt aatattttcc
     8101 tgtacctgtc tccttgcctt ggacatgtgt ccaggaaacc attgaatcgt agccatgtgt
     8161 gtaaaatcct ttcgtatcaa gggtttttag cccctcgtct tttaaaaatc atgcgagtca
     8221 ccaaaaaatc accaaatatt aagcattatc tccagaccaa gcgatataat tgcaacttgt
     8281 tttggttatt tttaatgcca acaatatcaa atgatttcta atggtatctg gcttatagct
     8341 attctctgct gaatagattg cctcttcaat tttaccctgt aatctcgctc agcctgtctc
     8401 ctgaccttgc ttttacatat gaaactgtaa tattt
//
LOCUS       DARYXW010000084         8134 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.084, whole genome shotgun sequence.
ACCESSION   DARYXW010000084 DARYXW010000000
VERSION     DARYXW010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8134)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8134)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8134
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.084"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            108..857
                     /locus_tag="TV191_001590"
     CDS             108..857
                     /locus_tag="TV191_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1508084.1"
                     /translation="MRVVILEDDMIQQRYLEKLIKELEVKHQLLFQGLDCFGRPHQLL
                     SAIKKNCGQQLFFLDIEIKNENKKGLEVARQIRQINPDAMIVFVTTHSEFMPLAFQYQ
                     VSALDYIDKELPQTEFVQRVETALLYAVRQNSETIAESAFYFTSRYAQVQVPFNDILY
                     IETSSRAHRVNLYTKKERMQFTGTLTDILKQESRFLQCHRSFLINHRNVVRVDKIERV
                     VYFRNGSSCLIARSKMNSVLTTIENLHRGDN"
     gene            857..2191
                     /locus_tag="TV191_001591"
     CDS             857..2191
                     /locus_tag="TV191_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEL1508085.1"
                     /translation="MKLILFFLEMTTSIGLSLVLFSKISGRQLTWLEVAFSTFLRIGF
                     AVFFTIANHVADISLLNYWSLPIYMVVISWLLLRPLSKTLLIFYGLFPITLWSLWYRL
                     LGFFILPLFKLDYHLTNDGFWGIFTDIVSTLMVFLFLRWLRYDFRALRINLLSDRDKR
                     ILGVTNWSMVSYYFLIQLLAYLEYELAVDTYAYRQCMMLGYWIIFMGTVSRLDRSLRD
                     TLQERLTFQRELQLANIESYSRQIEELYREVRGFRHDYSNLIATLKFGIDNDSMSIVR
                     SVYQSVFKDSNKRFRKQKYDVGRLIHVTDTALKSLLAAKFSQALESGISVSLEVPEDI
                     SPQGMELIDFLTIVSILCDNAIEAAVEASSSKITISYFTLDNKQLFMIENTTKEEKID
                     LSFLYDFGVSTKGDNRGVGLYNAMEIINRYPNVMIKTISQNHVFGQTLELRL"
     gene            complement(2313..2444)
                     /locus_tag="TV191_001592"
     CDS             complement(2313..2444)
                     /locus_tag="TV191_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="HEL1508086.1"
                     /translation="MDKPTRQPKFQELTPSQLTQITGGGWLEGLQKVFNVSKPKLLK"
     gene            complement(2544..3902)
                     /locus_tag="TV191_001593"
     CDS             complement(2544..3902)
                     /locus_tag="TV191_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEL1508087.1"
                     /translation="MNPNMFKSAEFYQRRYHHLTTFLTIPLALLLTFLILFSCFVYKE
                     ITVTSYGEITPTQVIATVQSISNNPIIANHLTNNQPIKQGDSIIQYAKDLEESQKQVL
                     EKQLATYEKQKSSLNTLLLSLKQGQNLFQNDDQFGYVNTFNHFMSQAQDIDLGFSKIK
                     AETSQQAQLIQDSIVAINQQINSLSQQISDYEELRSAIINQSDSLSSNNPHQATLDAY
                     LSQSQANQETATNQLLFQIDQNLLNLKTSIDSLYRQRANLHQSTSYDNSLNTKLEILR
                     TQFLITASQQLTDVNHHITELKAQLEQATLQVNNLVIKASKSGIVQLNSAFEGKISIP
                     IGHDIAYIYPSLKQTKQALLTYYVSSESVSLLKKNQVVRLALDRHGNQPIVITGTIKT
                     IDELATKTKQGNLFKVTAKLTLSEKESTTIQYGQQGRVISVIAKKTFFDFYKDKLFKV
                     TE"
     gene            complement(3913..6069)
                     /locus_tag="TV191_001594"
     CDS             complement(3913..6069)
                     /locus_tag="TV191_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEL1508088.1"
                     /translation="MTLFYKRTFVSQIDARDCGVAALASIARYYGSDYSLAHLRELAK
                     TNKEGTTALGIVMAAKEMGFETRPIQADMTLFDMADVPYPLIVHVNKEGKLQHYYVVY
                     KSKKDYLIIGDPDPMVKVTKMSKERFASEWTGVTICLAPKPNYKPHKDQKNGLLGFFP
                     LIFKQRTLIFYIVLASVLVTVINIAGSYYLQGILDEYIPNQLKSTLGIVSIGLIITYI
                     LQQLMSFSRDYLLTVLSQRLTIDVILSYIRHIFELPMSFFATRRTGEVTSRFTDANSI
                     IDALASTILSLFLDLSILAIVGSVLLVQNSRLFLLSLISIPVYTIIICAFIKPFEQMN
                     HDVMQSNAMLSSAIIEDINGIETIKSLTSEENRYQKIDSDFVDYLDKSFKLSKYTILQ
                     ATLKQGAQLILNIIILWFGAQLVINGKISIGQLITFNTLLAYFTTPLENIINLQTKLQ
                     AAKVANNRLNEVYLVESEFKASQALYDLSLLQGDIQFEAVSYRYGFGKDTLSDITLTI
                     KQGAKVTLVGVSGSGKTTLAKMLVNFFEPYKGRITINQNDLKTIDKKNLRQYINYLPQ
                     QAYVFNGSILENLTLGAKQGISQEDILNACEIADIRHDIEQMPMGYQTELSDGAGLSG
                     GQKQRIALARALLTQAPILVLDEATSGLDILTEKKIIDRLMNMTDKTIIFVAHRLSIA
                     ERTDQIVVLNQGQIIETGSHQELMKQGGFYYHLFSE"
     gene            6329..6577
                     /locus_tag="TV191_001595"
     CDS             6329..6577
                     /locus_tag="TV191_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="garvicin Q family class II bacteriocin"
                     /protein_id="HEL1508089.1"
                     /translation="MNMTLMKQFNIIDADKLAHIEGGGKGICKFVMSGSNGYACRYSN
                     GEWGYIVTKSNFEATKDVIVNGWISSLGGGYFHPGYRG"
     gene            6584..6880
                     /locus_tag="TV191_001596"
     CDS             6584..6880
                     /locus_tag="TV191_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL1508090.1"
                     /translation="MLTQEEILNKVYNLILDPTLTSEERVILVRFKDRVGESSNFDRE
                     VMMLSESLRQLAVKQIRVETMSVEMAKFYKEISTYKECDKQLGRGLISLGVIRR"
     gene            7622..7876
                     /locus_tag="TV191_001597"
     CDS             7622..7876
                     /locus_tag="TV191_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEL1508091.1"
                     /translation="MNTTLMKQFNIIDADKLAHIEGGKNNWQANVWEGGTAAVSGWGL
                     GTAICAASGAGAPFMGACGYIGAKFGVSLWAGVTGATGGF"
     gene            7893..8096
                     /locus_tag="TV191_001598"
     CDS             7893..8096
                     /locus_tag="TV191_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin BlpN"
                     /protein_id="HEL1508092.1"
                     /translation="MTHYYQIKEEELNDICGGNPAGAAVVGGLTCAVGGIKLGSRIGP
                     WGAVIGGVGSAAVCGYLAYKASS"
BASE COUNT         2354 a         1254 c         1810 g         2716 t
ORIGIN      
        1 tgatgcagtt gtttttaatg gatttatttt tgttattgtg cttattattt tgttgaaacg
       61 gtagtagtgc taatgcttct gcagattgga taggggactg agtttaggtg agagtagtta
      121 ttttagaaga tgatatgatt cagcagagat atttagaaaa gctcattaaa gagcttgagg
      181 ttaagcacca gctattattt caaggacttg actgttttgg aaggcctcat cagctattaa
      241 gtgctatcaa gaagaactgt ggtcagcagc tattcttttt agatattgag ataaaaaatg
      301 agaacaaaaa agggcttgag gttgctaggc aaattcgtca gataaatcca gatgcgatga
      361 ttgtttttgt aacgactcac tcggaattta tgcccttggc ttttcagtat caggtatctg
      421 ctttggacta tatcgataaa gagctgcctc aaactgagtt tgttcaacgg gtagagactg
      481 ctttattata tgctgtgcgg caaaatagtg aaacgatagc ggaaagtgct ttttatttta
      541 catctcgtta tgctcaggta caggtgcctt ttaatgatat cctgtatatt gagacatcgt
      601 cacgagcgca tcgtgtcaat ttgtatacaa aaaaggagag aatgcaattt acggggactt
      661 tgacggatat tttgaagcaa gagtctcgtt ttttgcaatg tcatcgttct tttttgatta
      721 atcataggaa tgtcgttagg gtagataaga ttgagcgagt ggtttatttt cgaaatggct
      781 ctagctgctt aattgctcgt agtaaaatga acagtgtttt aacaacaatt gagaacctac
      841 atagaggaga taattaatga agcttatttt atttttctta gaaatgacga caagtatagg
      901 cttatcgtta gtgctctttt ccaaaatcag tggacgtcaa ttaacctggc ttgaagttgc
      961 tttcagtact tttttaagaa taggatttgc tgtttttttc actatagcta atcatgttgc
     1021 cgacatttca cttctcaatt attggagtct tccaatttat atggtagtga tatcatggct
     1081 attgctgcga cccttatcaa aaacattatt gatattttat gggctatttc ctattaccct
     1141 gtggagcctt tggtaccgac tgcttggttt ttttatctta cctcttttta aacttgatta
     1201 tcatttaaca aatgatggat tttggggaat ttttacagat atagtatcta ctttgatggt
     1261 ttttctcttt ttgcggtggc tacgatatga tttcagagca ttaagaatta atcttttatc
     1321 tgatagggat aaaagaattt taggtgtgac caactggtct atggttagct attatttttt
     1381 gatccaattg cttgcttatt tagagtatga gctagctgtt gatacttatg cctatcgtca
     1441 atgcatgatg cttggctatt ggattatatt tatgggaact gtgtcgagac tggaccggtc
     1501 gctaagagat acactgcaag aaagactgac ctttcaaaga gagctgcagc tggcaaatat
     1561 tgagagctat agtcgtcaga tagaggagct ttacagagag gttcgaggat ttcgtcatga
     1621 ctatagcaat ctgattgcca cgttaaagtt tggtatagat aatgatagca tgtctattgt
     1681 taggtcagtt tatcaatcgg tctttaagga ttcaaataaa cgatttcgca agcaaaaata
     1741 tgatgttggg cgtcttatcc atgtcactga cacagccttg aaaagtcttt tagctgcaaa
     1801 atttagtcag gctttagaaa gtgggatttc agtatcttta gaggttccag aggatatcag
     1861 tccgcaaggc atggagctga ttgattttct tactattgtg tctattttat gtgataatgc
     1921 tatagaggct gctgttgaag cttcttcgtc taagataacg atttcttatt ttactttgga
     1981 caataagcaa ctatttatga ttgaaaatac aactaaggaa gagaagattg atctatcctt
     2041 tctatatgat ttcggagtaa gcaccaaggg ggataataga ggtgtgggac tttataatgc
     2101 tatggaaatt atcaatcgtt atcccaatgt gatgattaag actataagtc aaaatcatgt
     2161 atttggtcaa acacttgagc ttaggttata aaaaaacacc actagtaaag gaaaactgtc
     2221 ttgcacctat cagatttgat gtttaggatc acatcattcc gatagtgtct cagtaccttt
     2281 aggtagtggt gttttgaaaa tggagaatgt tactatttta gtagttttgg cttagagaca
     2341 ttgaaaactt tttgaagacc ttcaagccag cctcctccag taatctgagt taactgagaa
     2401 ggcgttagtt cctgaaactt tggttgtcta gttggtttat ccatattgaa agctcctttt
     2461 aaatactgtc tatgttatta tagcttatct tgactctttg ttgtactcta tgtcctaaat
     2521 ggtcgttgaa aagcgctaaa tggttattct gtcactttaa agagcttgtc cttataaaag
     2581 tcaaagaatg tttttttggc aataacactt atcactcgtc cctgctgacc atattgaata
     2641 gtagtgcttt ctttttcaga aagtgttagt ttggctgtaa ccttaaaaag atttccctgc
     2701 ttggttttgg tcgctagctc atcaatggtt ttaatggttc ccgtaatgac tatcggttga
     2761 tttccatgtc tatctagagc tagcctgaca acctggttct tcttaaggag agaaacagat
     2821 tcagagctga catagtaagt gagcaaggct tgttttgttt gtttgaggct aggataaatg
     2881 taggcaatat cgtgaccgat tgggatacta attttgcctt caaaagcact attgagctga
     2941 acaatgccac tttttgaggc tttgatcacc agattgttta cctgaagagt ggcttgctcc
     3001 aattgcgcct tgagctcagt aatatgatga ttgacatctg ttaactgctg agaggctgtt
     3061 atcaaaaact gtgttcggag tatttctagc tttgtgttga ggctattatc atagctggta
     3121 gattgatgta gattagcacg ttgcctatag aggctatcta tagaggtttt taggtttaaa
     3181 agattttggt ctatttgaaa tagaagctga ttggtggcag tctcttggtt tgcttgagat
     3241 tgagagagat aggcatcaag ggtggcttga tgtgggttat tggaggatag actatcggat
     3301 tggttaatga tcgcagatcg aagctcttca tagtctgata tttgttgaga aagactattt
     3361 atttgctgat tgatagcaac aatagagtcc tgaatcagct gggcctgctg gctggtctct
     3421 gcctttattt ttgagaaacc aaggtcaata tcttgggctt ggctcatgaa atgattaaag
     3481 gtattgacgt aaccaaattg atcatcgttc tgaaaaaggt tctggccttg ttttaagctt
     3541 aacaatagag tattaaggct gcttttttgc ttttcgtagg tagctaattg tttctcaagt
     3601 acctgctttt gagactcttc taggtcttta gcatattgaa taatagagtc tccttgtttg
     3661 attggctggt tattggtgag atggttcgca attataggat tattgctaat agattggact
     3721 gttgcaatga cttgagtggg agtgatttct ccgtaggacg ttaccgttat ttctttataa
     3781 acaaagcaag aaaaaaggat aagaaaagtc aacaagaggg ctaagggaat tgttaagaat
     3841 gttgtcaaat gatgatagcg tctttggtag aattccgcac ttttaaacat attgggattc
     3901 atgattgtct ccttattcac taaataggtg gtaataaaat ccaccttgtt tcattaattc
     3961 ctggtggctg cctgtttcaa tgatttgccc ttgattaaga acaacaatct gatcagtgcg
     4021 ctctgcgata ctaagccggt gggcaacgaa aataatcgtt ttgtctgtca tgttcatgag
     4081 acggtcaatg attttctttt ctgtcagtat gtcaagtccg ctggttgctt catcaagaac
     4141 tagtatagga gcttgggtta gtaatgctct agcaagtgca attctctgtt tttgtccgcc
     4201 agataagcca gccccatcag agagctcggt ttggtatccc attggcattt gctcgatgtc
     4261 gtgacgaatg tcagcaatct cacaggcgtt aagaatgtct tcctggctga tgccttgctt
     4321 ggctcccaag gttagatttt ctaagataga tccattaaac acataggctt gttgtggaag
     4381 gtagttgatg tattgtcgaa gattcttttt atcaatggtc ttgagatcgt tttggttgat
     4441 ggttatacgt cctttataag gttcaaagaa attgacgagc atcttggcta gggttgtttt
     4501 tcctgagccg ctgacaccaa caagggttac ttttgctccc tgcttaatgg ttaatgtaat
     4561 atctgataat gtatccttgc caaagccata cctgtaggaa acagcttcaa actgaatgtc
     4621 accctgtaag agcgataaat cgtataaggc ttgcgaggct ttaaattcgg actctacaag
     4681 atagacctca ttgagacgat tattggcaac cttagctgct tggagcttgg tttgaagatt
     4741 aatgatattt tctaaagggg ttgtaaaata ggcaagaagt gtgttaaagg taattaattg
     4801 cccgattgaa attttaccat taatgaccag ttgagcccca aaccaaagaa tgatgatatt
     4861 cagaattagc tgcgctcctt gcttaagtgt ggcttgtaag atggtatatt tactaagctt
     4921 aaaagactta tcaaggtaat ccacaaagtc gctgtcaatt ttttggtaac ggttttcttc
     4981 actggttagt gattttatgg tttcgatccc gttgatatct tcgataatag cagagcttag
     5041 catggcattg ctttgcatca catcatgatt catttgttca aacggcttta taaaggcaca
     5101 tatgataatg gtatatactg ggatagaaat cagagatagc agaaaaagcc tgctattttg
     5161 caccaaaaga acacttccga caatagctaa tatagagagg tctagaaaga gggataaaat
     5221 ggttgaagcg agtgcatcaa taatagagtt agcatctgta aagcgcgagg ttacctcacc
     5281 tgttcgacgt gttgcaaaaa aggacatcgg caattcgaaa atatggcgga tataggacag
     5341 aatcacatca atcgtaagac gttggctaag gacagttaaa agataatctc tagaaaagct
     5401 cattagctgc tggagtatat aggtaatgat gagaccaatt gatacaatcc ctaaggtaga
     5461 tttcagctga tttggaatat actcgtctaa aatcccctgg agatagtatg aaccagcaat
     5521 attaatgacc gttaccaaga cagaagctaa cacgatataa aatataaggg ttcgctgttt
     5581 aaaaataagc ggaaagaagc ctaatagtcc atttttttgg tctttatgtg gtttataatt
     5641 tggcttagga gcaagacata tggtgacacc tgtccattct gaagcaaagc gttccttgga
     5701 catttttgtg accttgacca ttggatcggg atcaccaatg ataagatagt cttttttaga
     5761 tttgtagacc acatagtagt gctgtagctt tccttcttta ttgacatgga cgatcaatgg
     5821 atagggcacg tctgccatgt caaagagggt catatccgct tgaatgggtc tggtttcaaa
     5881 tcccatttcc ttagcagcca tgacaatacc gagggctgtt gtcccttcct tattggtttt
     5941 tgctaattct ctcaaatgag ctaatgaata atctgaacca taataccttg cgattgaggc
     6001 tagagcagct acgccacaat ctctggcatc tatttgtgat acaaaggttc ttttataaaa
     6061 gagtgtcatt ggttggcttc ctttctctgt tgtaacgact ctattgtgcc acaaaagctc
     6121 agaaaaaaac tgagctagtc ttgaatagtc gttgaaacgt cttaaatggg aataatgata
     6181 ttaacactct tttttaatca gttgcgacat taccattcaa gacgtttcga cgacatttta
     6241 agacttaaat actgaaagca gttatttatc tgctatactg ggtttgttgc ttgcaacagg
     6301 taaaaaataa atataggaga tattcacgat gaatatgaca ttaatgaaac aatttaatat
     6361 tatagacgct gacaagcttg ctcacattga gggtggcggc aaaggaattt gtaagtttgt
     6421 aatgtctggt tctaatgggt atgcctgccg atatagcaat ggcgaatggg gctatattgt
     6481 tactaaaagt aattttgaag caactaaaga tgttattgtt aatggttgga tatcctcttt
     6541 aggaggtggt tatttccatc cagggtatag agggtagttg ggtatgttga cgcaagaaga
     6601 gatactaaat aaggtttata atttaatttt agatccaacc ttaacatcag aagagcgagt
     6661 cattctggta agatttaaag atagagtagg ggagtcaagt aactttgaca gagaagtgat
     6721 gatgctatct gaatctctgc gtcaattagc tgttaagcag ataagagttg aaacaatgag
     6781 tgtagaaatg gctaaattct ataaagaaat ctctacttac aaagaatgtg ataaacagct
     6841 aggtagaggc ctaatatcat tgggagttat taggcgataa taaaacgctc ataccttatc
     6901 gttgtattgg cgttattgtt ttgttgagtc acaataggcc aaatgacatg aaaaggttgt
     6961 caatgctatt ttgtgagatg gctagctgaa ggtaaagtaa gtaacgattg agttgattgg
     7021 ctaatcgcag gatataacaa tgggtatcag tttaaagctg atacctattg ttttgtggta
     7081 gttaactatc tagggtggtt tcggacaaga agtagcttga gataattgca agggcaataa
     7141 gcttatctca tttggttagt gatttatttt ttcttacaaa gaacttattt ttgagtctta
     7201 ttgagcttgg aaaagaaata ttatctgcgc tattagctat caaatcagtt gcttttcctt
     7261 atttctagag gcttaagtta gtaagctgag gccacaaatg tattattttc atcagctgtt
     7321 gatgatgtat tgctatctgg aaaaataaaa tagtcattta agattgggct atttgtcatt
     7381 acagcataga gccttcagcc gtcaaaggag gaaactcagc ttttgaagca attaagacag
     7441 ctttctcata tttgttatgg gtattaggaa ttttcactga attggtgtta acggttttcg
     7501 tattaccatt caagacgttt cgacgacatt ttaagactta aatactgaaa gcgattgttt
     7561 atctgctata ctgggtttgt cagttgcagc agacaaaaaa taaatatagg aggtattcac
     7621 gatgaatacg acattaatga aacaatttaa tattatagac gctgacaagc ttgctcacat
     7681 tgaaggtgga aagaataatt ggcaagctaa tgtttgggaa ggtggtaccg ctgctgttag
     7741 tggctggggg ttagggacag ctatttgtgc tgcaagtggt gccggtgctc catttatggg
     7801 agcatgtggt tacattggag ccaaatttgg cgtatcattg tgggcaggag taacaggagc
     7861 aacaggtgga ttttaatcaa gagaggtttt ttatgactca ttattatcaa atcaaagaag
     7921 aagaacttaa cgacatttgt ggagggaacc ctgccggtgc agcagtagta ggtggtttga
     7981 cctgtgctgt tggaggtata aagttgggaa gtaggattgg accttgggga gctgttatcg
     8041 gaggagttgg aagtgcagct gtttgtggtt atttagccta taaggcttca tcataatatg
     8101 atatgaatct gaaatatata tttactatag ttat
//
LOCUS       DARYXW010000085         8116 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.085, whole genome shotgun sequence.
ACCESSION   DARYXW010000085 DARYXW010000000
VERSION     DARYXW010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8116
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.085"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(3..2006)
                     /locus_tag="TV191_001599"
     CDS             complement(3..2006)
                     /locus_tag="TV191_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter Kup"
                     /protein_id="HEL1508093.1"
                     /translation="MSNAHHDAFDKATKAGFIIALGIVYGDIGTSPLYTMQSLVDNQG
                     GLSQVSEAFILGSVSLIIWTLTLVTTIKYVLIALKADNHHEGGIFSLFTLVRRMSRWL
                     IIPAMLGGATLLSDGALTPAVTVTSAIEGLKAVPELSSIYQNQTNVILTTLLILMVLF
                     GLQRFGTGVIGKLFGPVMLVWFSVLGISGLLNSLQHLEILKAINPYYALHLLVSPENH
                     RGIFILGSIFLATTGAEALYSDLGHVGRGNIYASWPFVKVCIILSYCGQAAWILAHKD
                     SGIALNPFFASVPEGLRVYLVILATLAAIIASQALISGSFTLVSEAMRLKIFPLFKIT
                     YPGANLGQLYIPVINWSLFAVTSCTVLYFRTSAHMEAAYGLAITITMLMTTILLAYYL
                     IKEGVKPLLASLLMAFFAFIEFIFFLASAVKFMHGGYVVVVLALAIVFVMVIWHAGTM
                     IVAKYVKSLSLNDYKHQIKLLRDDLRFDLYQTNVVYLTNRMKKDLIDRSILYSILDKR
                     PKRAQVYWFVNVRVTDEPYTATYKVDMLETDYIVCVELYLGFRMPQTVPRYLRTIVQD
                     LMESGRLPKQAQDYTITPGREVGDFRFVIIEERVSHARQLSTLERFVMQTKASIKHVT
                     ASPMRWFGLQYSEATVEVVPLLLSDVLKLPIKEIKACTKDEKA"
     gene            complement(2133..3749)
                     /locus_tag="TV191_001600"
     CDS             complement(2133..3749)
                     /locus_tag="TV191_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL1508094.1"
                     /translation="MKFTAFNLSEDIQSAVVTAGFEKASPIQELTIPLALEGRDVIGQ
                     AQTGTGKTAAFGLPTLNKIRTADNTIQALVIAPTRELAVQSQEELFRFGRDKGVKVRS
                     VYGGSSIEKQIKALKSGAHVVVGTPGRLLDLIKRKALRLDHVETLILDEADECLNMGF
                     LEDIEAIISRVPDDRQTLLFSATMPAPIKEIGVKFMKDPEHVQVKNKELTNVNVDQYY
                     VRVKEQEKFDTMTRLMDVQQPELSIVFGRTKRRVDEITRGLKLRGFRAEGIHGDLDQN
                     KRLRVIRDFKNDQLDILVATDVAARGLDISGVTHVYNYDITQDPESYVHRIGRTGRAG
                     KSGESITFVSPNEMGYLTMIEHLTKKRMKPLKPATAEEAFQAKKKVALKKIERDFADD
                     AIRSNFEKFKGDAMKLAAEFTPEELALYILSLTVQDPDTLPEVEIAREKPLPFKYVGG
                     GHGNKNGKTGRGNRSRSGRDNRRGGYRHEKRNVYDGDRRPRRDKRDSHDSSGSYDFKR
                     KQKRSNKDLHKKGKAVEAKTSGFIIRHKGN"
     gene            complement(4165..5709)
                     /locus_tag="TV191_001601"
     CDS             complement(4165..5709)
                     /locus_tag="TV191_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEL1508095.1"
                     /translation="MSITEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKSGQFAKSDWMDFEKQRGISVTSSVMQFDYAGKRINILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRNIPVFTFINKLDRDGREPLELLEELEEVLG
                     IASYPMNWPIGMGRAFEGLYDLHNKRLELYKGEQRFADLEEGARIFASNPFYEQVLED
                     IELLEEAGNDFSEQAILDGQLTPVFFGSALTNFGVQTFLDTFLAFAPEPHGHKTTTDQ
                     MIDPLNQDFSGFVFKIQANMDPKHRDRIAFVRIVSGEFQKGMAVKLSRTGKSVKLSNV
                     TQFMAESRENVQNAVAGDIIGVYDTGTYQVGDTLSVSKNLFEFEPLPTFTPEIFMKVA
                     PKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VIMTPMGKKTVRWISEEDLDQRMSSSRNILARDRFDQPVFLFENDFALRWFADKYPDV
                     KLEAKM"
     gene            complement(5878..6573)
                     /locus_tag="TV191_001602"
     CDS             complement(5878..6573)
                     /locus_tag="TV191_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEL1508096.1"
                     /translation="MNFFAIEPIGLPHVSLLFYLLSVMIAPFLVFMTLQLYQLKSYRY
                     IFLGLQLVQLVGLYSWYALRGFPLTEALPLYHCRMAMLAIFFLPDRSSLKQLFMVLGI
                     GGTFLALLSPDLYPYQLWHVANISFYLGHYALLVNGLVYLLRFYNPSQLKPVLVCRYL
                     ATINFVLVLINLATKGNYGFVMDIPIIHTHHLLMNFVIVTMGLTGLIKLIELIYVRFS
                     EANQLELKLSKER"
     gene            complement(6657..8042)
                     /locus_tag="TV191_001603"
     CDS             complement(6657..8042)
                     /locus_tag="TV191_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEL1508097.1"
                     /translation="MKLTLHEVARVVDAQNSLSDLDDVPLNQIEFDSRNITKGDLFLP
                     LQGERDGHDFIDLAFENGAVATFSERAISGRPYILVENCLAAFQKLAQYYIDKLRVDV
                     IAVTGSNGKTSTKDMIEAVLAKAYKTYKTQGNYNNDIGLPYTVLHMPEDTEKIVLEMG
                     QDHMGDIQLLSRIARPHIALLTLIGEAHLAYFGSREKIAEGKMQIVDGMDSNGILIAP
                     GDPILDPYLPDSQMVIRFGDHQELVVEDIKECKDSLTFRTNVLPRPVTLPLTGKYNAT
                     NAMIAAYVGKLLAVPDEDIIEALETVKLTRHRTEWVKAANGADLLADVYNANPTAMRL
                     ILETFAAIPANPNGKKIAVLADMKELGADSVALHSQLITSLDPKRIDQLVFYGDDIQA
                     LAKLASQDYPSGRVSFFKKNNREDQYEDMCQYLLTILEPNDQMLLKGSHSMLLANVVD
                     RLTAPHAGKSS"
BASE COUNT         2469 a         1932 c         1519 g         2196 t
ORIGIN      
        1 acctaggcct tttcatcttt tgtacacgct ttgatttcct tgattggaag ctttaagaca
       61 tctgataaga gtaaaggaac aacctcaact gttgcctcag aatattgcag gccaaaccaa
      121 cgcatagggc ttgctgtcac atgcttgata ctagcctttg tctgcatgac aaaacgttcc
      181 agagtactca gctgccttgc atgcgacacg cgctcctcaa tgatcacaaa cctaaagtca
      241 ccaacctctc gacctggtgt aatcgtgtaa tcctgagctt gcttaggcag acgaccactc
      301 tccatcaaat cctgaacaat cgttctaagg taacgtggaa cagtctgtgg cattctaaag
      361 ccaaggtaga gctctacaca aacgatatag tctgtttcta acatatccac cttgtaggtc
      421 gccgtataag gctcatctgt cacacgaaca ttaacaaacc aataaacctg tgcgcgctta
      481 ggacgcttat ctaaaataga atacaggatt gagcgatcaa tcagatcttt tttcatgcga
      541 ttggtcaagt aaacaacatt ggtctgatac aaatcaaagc gaagatcatc tctgaggagc
      601 ttgatttgat gcttgtaatc atttaggctc aaggacttaa catatttagc aacaatcatg
      661 gttccagcat gccaaatcac cataacaaag acaatggcaa gagctaaaac aacaacaaca
      721 tagcccccat gcataaactt aactgcagac gctaaaaaga aaataaactc aataaaggca
      781 aaaaaagcca tgagcagact agccaggagc ggctttaccc cctccttaat aaggtaatag
      841 gctaagagaa tcgttgtcat cagcatggta atcgtgatgg caaggccata ggcagcctcc
      901 atatgcgctg atgttctaaa atacagcacc gtacaagacg ttaccgcaaa caagctccag
      961 ttaatgacag ggatgtatag ttggcctagg ttggcacctg gataggtaat cttaaacaac
     1021 ggaaaaatct tcaagcgcat agcctcagaa accaaggtaa aggaacctga gattaaagcc
     1081 tgcgaagcaa taatggctgc tagagttgct agaataacaa gataaacccg taatccctct
     1141 ggaacactag caaagaaggg attaagcgca atgcctgagt ccttatgcgc taaaatccaa
     1201 gctgcctgac cacaatagga taagatgata caaaccttaa caaagggcca gctagcataa
     1261 atatttcctc gaccgacatg acctaaatca gaataaagag cttcagcacc agttgtcgct
     1321 aaaaaaatag agcctaaaat gaaaataccc cgatgatttt ccggactaac caataagtgc
     1381 agcgcataat agggattgat agcctttagg atttccaaat gctgtaagct attcaagaga
     1441 ccactgatcc ccaaaacgct aaaccaaacc agcatgactg gcccaaataa tttaccaata
     1501 acacccgttc caaagcgctg caggccaaac aagaccatca atatcagcaa ggtcgttagg
     1561 atcacattgg tctgattctg gtaaatactg ctgagctcag gaacagcctt taagccttca
     1621 atggctgatg tgaccgtaac agctggtgtc aaggcaccat ctgataagag cgttgctccc
     1681 ccaagcatag ctggaatgat taaccacctt gacatccttc taactaaggt aaagagtgaa
     1741 aaaatccctc cctcatgatg attatcagcc tttaaagcaa tcaaaacata cttgattgtc
     1801 gttaccaagg ttagagtcca aataatcaag gatactgagc ctaaaataaa agcttcagac
     1861 acctgtgaaa ggccgccttg attgtcaacc aacgactgca tggtatacag tggacttgtg
     1921 ccaatatcac catagacaat tcctagtgca ataataaaac ctgcctttgt tgctttatca
     1981 aaggcatcat gatgggcatt agacatccca atgttcctcc taagacttaa tcatgccaaa
     2041 tggactgaga ccattatagc aaaatctata acaaaatcaa tattttcaga aaattaaaaa
     2101 gagagctgac aatcatcagc tctcttgaaa ctttagttcc ctttatgacg gataataaat
     2161 ccagacgtct tagcttcgac agccttgccc ttcttgtgca ggtccttgtt agagcgtttt
     2221 tgctttcgct taaagtcata gctaccactg ctatcatgac tgtcacgttt atcacgcctt
     2281 ggacggcggt caccatcata aacatttctt ttctcatgac gatagccacc tcgacggtta
     2341 tcacgaccgc tacgactacg attgccacga cctgtcttgc catttttatt gccatgacca
     2401 ccaccaacat acttaaacgg taatggcttt tcacgcgcta tctcaacctc tggtaaggta
     2461 tctggatctt ggacggtcaa gctaaggata tagagcgcta gctcctctgg ggtaaactct
     2521 gctgccaatt tcatcgcatc gcccttaaat ttctcaaagt ttgagcgaat agcatcatct
     2581 gcaaaatcac gctcaatttt tttgagggca acctttttct tagcctgaaa ggcttcctct
     2641 gccgtagctg gcttgagtgg cttcatgcgc ttcttagtca ggtgctcaat catggtcaga
     2701 tagcccatct catttggtga gacaaaggta atggattccc ctgacttacc tgcacgaccg
     2761 gtccggccaa tacggtgcac atagctttct ggatcctgtg taatatcgta attgtacaca
     2821 tgagtaacgc ctgaaatatc aagcccacgc gcagcaacat cggttgccac taaaatatca
     2881 agttgatcat ttttaaagtc gcgtatgaca cgaaggcgct tattttggtc aaggtcacca
     2941 tgtatccctt ctgcgcgaaa accacgcaat tttaagccgc gcgtgatttc atcaacacga
     3001 cgctttgtgc gaccaaatac aattgatagc tctggctgct gaacgtccat cagacgtgtc
     3061 atggtatcaa atttttcttg ctccttaaca cgcacatagt attgatcaac attcacattt
     3121 gttaattcct tgtttttaac ctgaacatgc tcaggatcct tcataaactt gacaccaatt
     3181 tccttgattg gagctggcat tgttgctgaa aataacaggg tttgacgatc gtcagggaca
     3241 cgactaataa tcgcttcaat gtcctctaaa aatcccatat tcaagcattc atcagcttca
     3301 tctaaaatga gtgtctcaac atggtctagc ctcaaggcct tacgcttaat caaatctaac
     3361 agacgtcctg gcgttccaac aacgacatgc gccccagact ttagggcctt aatttgcttc
     3421 tcaatgcttg agccaccata tactgagcga accttgacgc ctttatcacg accaaaacgg
     3481 aacagctctt cctgactttg gacagccagc tcacgcgtcg gagcaatcac caatgcctga
     3541 atggtgttat cggctgtacg aatcttattc agagttggta gaccaaaggc tgctgttttt
     3601 cctgttcctg tctgagcctg tccgataaca tctcgtccct ccaaggctaa cggaatggtc
     3661 agctcctgaa taggagaggc tttttcaaag cctgctgtaa caacagctga ctgaatatct
     3721 tctgataagt taaatgctgt aaatttcaat tgtttctctt ttctaaaaag gcagtgcgaa
     3781 gctgccttat aaacctttta atattgtcgt tcgattaaca acctatttag tgtaacataa
     3841 ttaatattaa aaagatagga aataagccat gaaagtgttt ttatctcaaa atgattaaca
     3901 ctatcaggca gctaaattga taaaagcgtc actccttatt gctgattggc taacagcctc
     3961 aaaaaggcct cgtcggactt gcttacctat gctttttatc tactctgcta aaaagactcg
     4021 gcacagagac gagccttcgc gattccatca ccaatcttca aagacagcaa ttaggattcc
     4081 tgaaagctcc ttatgccaat agcctgcctt ttcttagcag cagaagtgca aaaacggact
     4141 aggttcccct aatccgctta gctgctacat ttttgcttct agcttaacat ctgggtattt
     4201 atctgcaaac caacgaagcg caaagtcatt ttcaaagaga aaaacaggct gatcaaagcg
     4261 atcccttgcc aaaatgtttc ggcttgagga catgcgttgg tccaaatcct cctctgagat
     4321 ccaacgaaca gtctttttgc ccattggtgt catgatgacc tctgcattgt actcaccctc
     4381 catacggtgc ttgaaaacct caaactgcag ctgaccaact gcgcccagca tgtattcacc
     4441 tgtctgataa ttcttataaa gctgaacagc cccctcctgt acaagctgct caataccttt
     4501 gtggaaagat ttttgcttca tgacattctt aggtgcaacc ttcataaaaa tctctggggt
     4561 aaaggtcggc aatggctcaa attcaaacag gtttttacta acgctcaagg tatctccaac
     4621 ctgataagtc cctgtatcgt agaccccaat aatatcaccg gcaactgcat tttggacatt
     4681 ttcacgagac tcagccataa actgagtaac atttgatagc ttaacgcttt tacctgtacg
     4741 agacagcttt acagccattc ccttttgaaa ctctccagag acaatacgca caaaggcaat
     4801 gcggtcacga tgcttagggt ccatgttagc ctgaatctta aagacaaagc ctgaaaaatc
     4861 ctgattgagg ggatcaatca tctggtccgt tgtcgtctta tgcccatgag gctctggtgc
     4921 aaaggctaaa aaggtatcta aaaaggtttg taccccaaaa tttgttaagg cagagccaaa
     4981 gaataccgga gtcagctgac catctaaaat agcctgctct gaaaagtcat tacctgcctc
     5041 ctccaagagc tcaatatctt caagcacctg ctcataaaaa gggttgctgg caaaaatcct
     5101 tgccccctcc tctaaatcag caaacctctg ctccccctta taaagctcca agcgtttgtt
     5161 gtgcaaatca tacagacctt caaaggctcg tcccatacca attggccagt tcatggggta
     5221 agaagcaatc ccaagaacct cttctagctc ctccaacaac tccaaaggct cacgtccatc
     5281 acgatctaat ttattaataa acgtaaaaac aggtatgtta cgatgcttaa caacctcaaa
     5341 gagctttttc gtctgtgctt cgatcccttt agccgaatca acaaccatca cagcagcatc
     5401 aactgccatt aaggtacgat aagtatcctc tgaaaagtcc tcgtgaccag gtgtatctaa
     5461 aatattgata cgcttaccag cataatcaaa ctgcatgact gatgatgtga ctgaaatccc
     5521 acgttgcttt tcaaaatcca tccaatctga cttagcaaat tgaccagatt tttttccttt
     5581 aacggtccca gcctcacgaa tctcaccacc aaaataaagt aactgttctg taatagttgt
     5641 tttaccagca tctgggtgac tgataatcgc aaaggttcga cgctttttaa tttcttctgt
     5701 aattgacatt cttttttcct tatttgttca cattgcagag caagactctg attaatagct
     5761 tcaagtcaca cgtcacagtt atgtctacat gatctcactc ctaaatactg atatgataaa
     5821 aagagctgct agagcagctc ctttattata gctgattcga agcgcttttt caacgcccta
     5881 tctttcttta gagagcttca gctctaactg attggcctca ctaaatctca catagataag
     5941 ttcaatcagc ttaattaaac cagtcaaccc cattgtcaca atgacaaaat tcataagcag
     6001 gtgatgcgta tgaataatcg gaatatccat cacaaagccg taatttccct ttgttgccaa
     6061 attgatcaat actaaaacaa aattaatggt tgccaagtaa cggcaaacaa ggactggctt
     6121 tagctgactt ggattgtaaa accgcagcag gtaaaccaag ccattgacca aaagagcata
     6181 atgccccagg taaaaagaaa tattagccac atgccatagc tgataagggt ataaatcagg
     6241 tgataacagg gccaaaaagg tcccaccaat ccctaaaacc ataaaaagct gctttaagct
     6301 actgcgatcc ggtaagaaaa agatagctag catggccatt cggcaatggt aaagcggcaa
     6361 agcctctgtc aacggaaagc ctcgcaaggc ataccagcta tacaaaccaa ccaattggac
     6421 caactgaagc cctaagaaga tatagcgata cgactttagc tgatagagct gcagggtcat
     6481 aaaaaccaaa aacggcgcta tcatcaccga caatagataa aatagcaagg acacatgcgg
     6541 tagcccaata ggttcaattg caaaaaaatt cataaacatc cctttctaca ttttttcatt
     6601 ataccttaat cttaatgaga ggacaagatg tttcatgtgt tttttctgaa aaagtgttag
     6661 gaggacttcc cagcatgagg agctgtcagg cgatcaacca catttgctag cagcatggag
     6721 tggctgccct ttagcagcat ctggtcatta ggctcaagaa tagtcaacag gtactggcac
     6781 atgtcctcgt attgatcctc tcgattattc tttttaaaga agctaactct gccacttgga
     6841 taatcttgac tagctagctt ggccaaggct tgaatatcat caccgtaaaa gaccaattga
     6901 tcaatacgct tgggatctaa gctggtaatc agctgagaat gcaaagcaac tgagtcagca
     6961 cctaattcct tcatatcagc taaaacagct atttttttgc cattagggtt ggccggaatg
     7021 gcagcaaagg tttccaaaat taaccgcata gcagttggat tggcattgta cacatctgcc
     7081 aaaaggtcgg cgccattagc cgccttgacc cactcggttc ggtggcgtgt cagcttgacg
     7141 gtttctaaag cttctataat atcctcatca ggcacagcca agagtttacc aacataagct
     7201 gctatcatag cattggttgc attgtatttt ccagttaagg gaagagtgac cggtcttggt
     7261 aagacattag tcctaaaggt caaggagtcc ttgcactctt tgatatcctc aaccaccagc
     7321 tcttgatgat cgccaaagcg aatgaccatc tgactatccg gcaaatatgg atcaaggata
     7381 ggatcaccag gagcaattaa aatcccgtta gagtccatcc catcaacgat ttgcattttc
     7441 ccttcggcaa tcttctcgcg agagccaaag taggctaagt gagcctcacc aataagggtt
     7501 agcaatgcaa tatgaggtct ggcaattcta gagagcagct gaatgtctcc catatgatcc
     7561 tgccccatct ctaaaacaat cttctcagta tcctctggca tgtgaagcac cgtataaggc
     7621 aagccaatgt cattattata attgccctgg gttttgtagg tcttataagc ttttgccagg
     7681 accgcttcaa tcatatcctt ggttgatgtt ttaccgtttg agcctgttac agcaatgaca
     7741 tcgacacgta gcttatcaat ataatactgg gctaattttt gaaaggcagc caagcaattc
     7801 tcaactagta tatagggtct gccactgatt gctctttctg aaaaggtagc tacggcccca
     7861 ttttcaaagg ctaagtcaat aaaatcatgg ccatctcgct caccctgtag cggtaaaaaa
     7921 agatcacctt ttgtgatgtt tctactgtca aattcaatct gattcagagg aacgtcgtct
     7981 aaatcagaaa gactattttg agcatcaaca actcttgcca cttcatgtaa tgttaatttc
     8041 atcttatttt tcctcttaaa acactggttt ttaaagcttt gcttatatta tagcataaca
     8101 tattaggaat attctt
//
LOCUS       DARYXW010000086         8031 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.086, whole genome shotgun sequence.
ACCESSION   DARYXW010000086 DARYXW010000000
VERSION     DARYXW010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8031)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8031)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8031
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.086"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(80..1285)
                     /locus_tag="TV191_001604"
     CDS             complement(80..1285)
                     /locus_tag="TV191_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEL1508098.1"
                     /translation="MKISVAGSGYVGLSLSILLAQHNDVTVVDIIDEKVRLINQGISP
                     IKDADIEEYLKNAPLNLTATLDGASAYSNADLIIIATPTNYDSERNYFDTRHVEEVIE
                     QVLDLNASATIIIKSTIPLGFIKHVREKYQTDRIIFSPEFLRESKALYDNLYPSRIIV
                     SYEKDDSPRVIQAAKAFAGLLKEGAKSKDTPVLFMGSQEAEAVKLFANTFLAMRVSYF
                     NELDTYSESKGLDAQRVIEGVCHDQRIGNHYNNPSFGYGGYCLPKDSKQLLANYRGIP
                     QSLMSAIVESNKIRKSYLAEQILDRASSQKQAGVPLTIGFYRLIMKSNSDNFRESAIK
                     DIIDIINDYGVNIVIYEPMLGEDIGYRVVKDLEQFKNESTIIVSNRFEDDLADVIDKV
                     YTRDVFGRD"
     gene            complement(1538..2791)
                     /locus_tag="TV191_001605"
     CDS             complement(1538..2791)
                     /locus_tag="TV191_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEL1508099.1"
                     /translation="MRTLKNLITVVAFSIFWVLLIYVNVYLFGAKGSLSIYGFLLIAY
                     LLVKMSLSFFYKPFKGRAGQYKVAAIIPSYNEDAESLLETLKSVQQQTYPLAEIYVVD
                     DGSADETGIKRIEDYVRDTGDLSSNVIVHRSEKNQGKRHAQAWAFERSDADVFLTVDS
                     DTYIYPDALEELLKTFNDPTVFAATGHLNVRNRQTNLLTRLTDIRYDNAFGVERAAQS
                     VTGNILVCSGPLSVYRREVVVPNIDRYINQTFLGIPVSIGDDRCLTNYATDLGKTVYQ
                     STAKCITDVPDKMSTYLKQQNRWNKSFFRESIISVKKIMNNPFVALWTILEVSMFMML
                     VYSVVDFFVGNVREFDWLRVLAFLVIIFIVALCRNIHYMLKHPLSFLLSPFYGVLHLF
                     VLQPLKLYSLFTIRNADWGTRKKLL"
     gene            complement(3188..3808)
                     /locus_tag="TV191_001606"
     CDS             complement(3188..3808)
                     /locus_tag="TV191_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508100.1"
                     /translation="MRKYLQIRLYELSHYVEIIISIILVISLLVLTGRLALSLTGIFT
                     IKSGIDTYLQSFLNQAMSIAIGVELIKMLSKHTSGTIIEVLLFAIARQIVVAHGSAKD
                     SLLSVIALAILFATRKYLFTSFDDTSSIIVRGSQKVKIANVLARVELPVINKNELMRD
                     LMLRHLEEEGKTATIGASIAFSDVALRVDHMHEGVITRIEIIKSLK"
     gene            complement(3849..3944)
                     /gene="ffs"
                     /locus_tag="TV191_001607"
     ncRNA           complement(3849..3944)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="TV191_001607"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            4121..5347
                     /locus_tag="TV191_001608"
     CDS             4121..5347
                     /locus_tag="TV191_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein"
                     /protein_id="HEL1508101.1"
                     /translation="MKNKLSLFLLAALTIVGLSACAWRSNPLADKEQQFGLTGARRQQ
                     VLDQIDQRYYYQQLSQAEKENYLLLYDSLSAFHEVTSLAPASKHSLMTTIDAFMMDNP
                     AFFWITSANYRLERSDQVAFVTFPLPEKVEQTYHRLQAIGDDIIADMPATNDYERVRY
                     FYEWIIKQTDYNRDAFEAYQSGHEALIASNQDIRSVFLDHLSVCNGYAQAFQFLCQKA
                     GIPVAYIRGSVTFDRSQDVFTHAWNTVQIAGKNYAVDTTFGDPVFDQNESIKQLEVNY
                     NFLCLPDQLMKQSHQASRDIVINQTETLTDVWTIPECSDDSLLYTKLNHSYFTAFDRP
                     DILASLEQQLRTNQPQTSLQFANQDLYNQMVSDLEQHSDSYHSLFQAYWPNAAGYFYS
                     LHPSTFSISISIINQQ"
     gene            complement(5457..5951)
                     /locus_tag="TV191_001609"
     CDS             complement(5457..5951)
                     /locus_tag="TV191_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEL1508102.1"
                     /translation="MSYSKQEQEYFMREALKEAEKSLLKDEIPIGCVIVKAGHIIGRG
                     HNAREERNQAIMHAEIMAINEANAHEGNWRLLDTTLFVTIEPCVMCSGAIGLARIPHV
                     VYGASNQKFGGAGSLYQILTDERLNHRVQLEVGLLADDCAKLMQTFFRQRRDQKKQDK
                     ESKI"
     gene            complement(5948..6730)
                     /locus_tag="TV191_001610"
     CDS             complement(5948..6730)
                     /locus_tag="TV191_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEL1508103.1"
                     /translation="MKLTTLGSWGAYPYQDAGTTAYLVTGHDGFQLLMDAGSRSLNEL
                     EKEINPLDLDAVIISHYHPDHVADLGVLRHYYQLYPRHLGKPRLLPIYGHDEDEAEFA
                     KLTLPGVSKGIAYQVDRVEALGPFDITFIKTVHPVVCYAFRIVERATGQVLVFTGDTG
                     YFEELADFAAEADVFLADVYLYEGNEHHMAHLTSKEAGQLASRAKVKRLVLTHMPPLP
                     PEGIDPKRHLEVLRQQAQGYAGQIPVDLALPHRAWDLGSLSQ"
     gene            complement(6829..7368)
                     /locus_tag="TV191_001611"
     CDS             complement(6829..7368)
                     /locus_tag="TV191_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEL1508104.1"
                     /translation="MLSTKDLVKVAMMTTLIIILGLIPAIPLGFVPVPIVLQNLGVML
                     AGLILGGKKGTLSILLFLVIGLFLPVFSGSRTTVPVLMGPSAGYVLAWLFVPLVFAFL
                     YRSWLARYRSLAFLAIFISGVLLVDLLGTIWLAVYTDMPLTRSLVASLVFIPGDTIKA
                     VIATALAVSYKDSFLNTNS"
     gene            complement(7372..7683)
                     /locus_tag="TV191_001612"
     CDS             complement(7372..7683)
                     /locus_tag="TV191_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508105.1"
                     /translation="MRNCFGIALDQEYRCVHYHTVLDIVGLKCARCQAYYACYHCHDT
                     LQDHAFEPTDHKETYPVICGHCRQLLRRSEYECGSCPFCFSPFNPAYHKHQDIYFSKE
                     L"
BASE COUNT         2410 a         1879 c         1562 g         2180 t
ORIGIN      
        1 tgggataatg gcttttctga cctttgtcat gagttcctcc ttgatttgtg gttccttatg
       61 tgtgccactt gttttctgac tagtctcttc caaagacatc tctcgtgtaa accttgtcaa
      121 tgacatctgc taggtcgtcc tcaaagcgat ttgacacaat gattgtagac tcgtttttga
      181 actgctctaa atcctttaca actctatagc caatgtcctc accaagcatg ggttcgtaaa
      241 tgacaatatt aaccccatag tcgttgatga tatcaataat atctttaatg gcgctttctc
      301 ggaaattatc agagttgctt ttcataatca agcggtaaaa gccaatcgtt aatggtacac
      361 cagcctgctt ttgactagag gctctgtcta atatttgttc agccaaataa gattttcgta
      421 tcttgttgga ttcaacaatc gctgacatca aggactgggg aatgcctcta taatttgcca
      481 acagctgctt gctgtccttt ggcaggcaat agccgccata tccaaaggaa gggttattgt
      541 aatggttacc aatgcgctga tcatgacaga ctccttcaat cacgcgctga gcatctagac
      601 ccttgctttc ggaataggtg tctaattcat taaagtaaga cacccgcata gccaaaaagg
      661 tattcgcaaa tagcttgacc gcctcagcct cctgtgagcc cataaataag accggagtat
      721 ccttgctttt ggctccttcc tttaaaagac cagcaaaggc tttagcagcc tgaataaccc
      781 ttggtgagtc gtccttttca taagaaacaa tgattcgact tgggtaaagg ttatcgtata
      841 aggcttttga ttctcttaaa aattctgggc taaaaataat acgatctgtc tggtattttt
      901 ccctaacatg cttgataaag cctagtggta tggttgattt gataataatg gttgctgacg
      961 catttaggtc taggacctgc tcgatgacct cttcaacatg ccttgtgtca aagtagttgc
     1021 gttcgctgtc ataatttgtc ggagtagcaa tgataataag gtctgcattg ctataagcgc
     1081 ttgcgccatc aagcgtcgct gtgagattta gcggcgcatt ttttaaatac tcctcaatat
     1141 cagcatcctt gattggcgat atgccttgat tgatcaatct caccttttca tcaataatgt
     1201 caacaacagt gacgtcatta tgttgtgcca gtaaaatact caaggatagg ccgacatatc
     1261 ctgagcctgc tacagaaatt ttcacttcat tttttccttt gataccttag tacagttagc
     1321 tactgccgga gctcaggtgc cacacctgaa ggaccatgat gacctagccc tcataccaaa
     1381 gctgacgctc agcctctggt tcgtcttcac agggctacaa gctaaaagct cttaactcaa
     1441 gtacaagtgg actagcttta tttgatgagc tgcttaactc aagatgcttt gttcactcct
     1501 agcttagctc ccttgtcaga acctaggtct agttggttta taataatttt ttacgtgttc
     1561 cccagtcagc atttctaata gtaaaaagag aatacaattt caagggctgt aggacaaaca
     1621 aatgcagcac cccataaaac ggagataaca agaaggacag cgggtgctta agcatgtaat
     1681 gaatgttccg acaaagagca acaatgaaga taatcaccag aaaggctaaa accctgagcc
     1741 aatcaaattc tctgacattg cctacaaaga aatccaccac agaataaaca agcatcataa
     1801 acatagacac ctcaagtatg gtccataggg ctacaaaagg attgttcatg attttcttaa
     1861 cagaaataat ggactctcta aagaaggact tgttccagcg gttttgctgc ttcaagtaag
     1921 tagacatctt gtcaggaaca tctgtaatac atttagcagt ggattgataa acagtctttc
     1981 ctaaatcagt tgcatagttg gtcaagcacc tgtcatcacc gatacttaca ggaataccca
     2041 ggaaggtctg gttgatgtat ctgtctatat taggaacaac cacctcgcgt ctgtaaacgc
     2101 taagtgggcc tgagcaaaca aggatattac ccgtaactga ttgggcagct cgttcaacgc
     2161 caaaagcatt atcatagcga atatctgtca agcgtgttaa gagattggtt tgtctatttc
     2221 tgacattaag gtgacccgtc gcagcaaaaa cagttgggtc attaaaggtc tttaacagct
     2281 cctctaaagc atcagggtag atataagtat ctgagtcaac ggtcaaaaag acatcagcgt
     2341 ctgatctttc aaaggcccag gcctgtgcat gacgctttcc ttgatttttc tctgaccgat
     2401 gaacaatgac attgcttgat aggtcaccag tgtcacgcac atagtcttca atgcgcttaa
     2461 tacctgtctc atcagcactt ccatcgtcaa caacataaat ttctgctagg ggataggttt
     2521 gctgctgaac actttttaag gtctctagca atgactcagc gtcttcgtta taagagggaa
     2581 taatggctgc aaccttatat tgcccagccc ttcccttaaa tggcttgtaa aaaaaagata
     2641 aggacatttt gactaataga taagctatca gcaaaaagcc ataaattgac aagcttcctt
     2701 tagcaccaaa gagataaaca ttgacgtaaa tcaacagtac ccaaaaaata ctaaaggcca
     2761 caacagttat gaggtttttt aatgttctca ttgtgattgg tttgatcctc tcttgcgctt
     2821 tgtattttgc ctttaaacgc taaccataat ataccatctg tcacagcaag caaacaaggt
     2881 cattaattta ccattctatt aaagatagat taatcttagt gtcaatacag ctttttctaa
     2941 gatttgccta tgctcaccaa gtcatcaatc ccctacaaaa aacaaatgat agcctgagtc
     3001 tacctgtggc tatcgctagc atgtgcctga taacaagcag ctaaatggcc cgtccaaaac
     3061 taaggcgctt tggacagccg cttttcgctc tcttttttga catcaaaaaa gcagccctta
     3121 tcaggccact tcatattggt aacaaagcaa ttctataagg agctccttaa aggataaggg
     3181 caagagatta ctttagagac ttgatgatct caatgcgagt gataaccccc tcatgcatat
     3241 gatctactct taaggcaaca tcagaaaaag caatagatgc cccaatcgtt gcagtctttc
     3301 cttcctcttc caaatggcgc agcattaaat cacgcattag ctcgtttttg ttaataaccg
     3361 gcagctcgac acgcgctagc acattagcta ttttgacctt ttgactgccc cgaacgataa
     3421 tgcttgaagt atcatcaaag cttgtaaaaa ggtattttcg cgtcgcaaat aaaatagcaa
     3481 gagctatgac actcaacaaa gaatccttag cagagccatg agcgacaaca atttgccggg
     3541 caatcgcaaa caaaagcacc tcaataatgg ttcctgaggt atgcttactc agcattttaa
     3601 tcagctcgac accaatagca atactcatgg cctggtttaa aaagctctgt aaataggtat
     3661 caatgccact ttttatggta aaaatacctg tcaagctcaa ggccaagcgc cctgtcagca
     3721 ctagtaacga aatcaccaag atgatggaaa taataatctc aacataatga gatagctcat
     3781 acaatctaat ctgcaaatat tttctcatag caactcctta tcattattat ataaaaaatg
     3841 ccactatttg aaaataaaaa aagagcacac acccgatatc gcttagggct gctggattcc
     3901 tcccctgacc cacttcacgc acaagtgttg ctccaccttt attgtagcat atattgtacc
     3961 ctaaaacaag tcttatttca aaaacgtctc acatctggct cataaagctt aattagctca
     4021 acagcaaacc aagcaaacgc tatcaataag gccagtcctt aaagctaagc ccgactagac
     4081 ttgtgctata atggtactaa caaacctgag tggagatgat atgaaaaaca agcttagcct
     4141 attcttgctg gcagcactta ctatagtcgg tctctcagcc tgtgcatgga gatccaatcc
     4201 tcttgctgac aaggagcagc agttcggcct gactggagca agacgtcagc aggtgcttga
     4261 tcagatcgat caacgttatt attaccagca gcttagtcag gcagaaaagg aaaattacct
     4321 tctcttgtat gatagcctct cagcctttca cgaggtgact agcctagcac cagcttctaa
     4381 gcatagcttg atgacaacca ttgatgcctt tatgatggat aatcctgcct ttttctggat
     4441 tacctcagcc aactaccgct tggaacgctc ggatcaggtg gccttcgtta cctttccatt
     4501 gccagagaag gtcgaacaaa catatcacag gcttcaagcc attggagatg atatcatcgc
     4561 tgacatgcca gcaaccaatg actatgagcg cgtgaggtat ttttatgagt ggatcatcaa
     4621 gcaaactgac tacaatagag atgcctttga ggcatatcaa tcgggtcatg aggccttgat
     4681 agcctctaat caagacattc gcagtgtctt tcttgatcat ctttctgtct gcaacggcta
     4741 tgcacaggcc tttcagtttc tttgccaaaa ggccggtatt cctgtcgcct atattcgagg
     4801 gtcagtcacc tttgatcgat cacaggacgt ttttactcat gcttggaata ctgttcagat
     4861 tgcaggcaag aactatgctg ttgacacaac ctttggagat cccgtctttg atcaaaacga
     4921 atccattaaa caactagagg ttaattataa ctttttatgc ttgccagacc agctcatgaa
     4981 gcagtcgcat caagccagca gggatattgt gatcaatcag acagaaacct tgaccgatgt
     5041 ctggacaatt cctgagtgct cagacgattc tctgctctat actaagctca atcacagcta
     5101 ctttactgcc tttgatagac cagacattct ggccagtctt gagcagcaat taaggactaa
     5161 tcagccacag accagcttac aatttgctaa tcaggacctc tacaaccaaa tggtaagtga
     5221 tcttgagcag cattctgaca gctaccatag cctgtttcaa gcttattggc ctaatgctgc
     5281 tggctatttc tacagtctac accccagcac ctttagcatt agcattagca ttatcaatca
     5341 gcaatagcct aataccctga cagacaagta caagcgctta tggcatggct ctaccagcca
     5401 ttaaagagct gtgctaggct ctcaagggtc ttttttcttg ctaatcgctc aatgggctaa
     5461 atcttacttt ccttatcctg ctttttctgg tcacgccttt gccggaaaaa ggtctgcatg
     5521 agcttggcac agtcatcagc caaaagacct acctcaagct gtacacgatg gttcaggcgc
     5581 tcatcggtta agatctgata aagactacca gcaccgccaa acttttgatt gctggcccca
     5641 tagaccacat gaggaattcg agctagccca atggctccgc tgcacatgac acaaggctca
     5701 atcgtcacaa aaagagtcgt atccaagaga cgccaattgc cttcgtgcgc attggcttca
     5761 ttaatggcca tgatctcagc atgcataatc gcctgattgc gctcctcgcg agcattgtga
     5821 ccacgcccga taatgtgacc agccttcaca ataacgcagc caatcggtat ctcgtccttt
     5881 agcagcgatt tctcagcctc cttgagggct tctcgcataa aatactcttg ctcttgtttg
     5941 gaatagctca ttgagataga ctccccaaat cccaagcccg atgtggcaga gcaagatcaa
     6001 caggaatctg accagcatag ccttgagctt gctgtcgcag cacctccaaa tgcctcttag
     6061 gatcaatccc ctctggcggc agaggtggca tatgggtcaa gaccaagcgt ttcaccttag
     6121 cacggctggc aagctgccca gcctcttttg aggtcaaatg cgccatatga tgttcattgc
     6181 cttcataaag gtacacatct gctaaaaaca catcagcctc cgcagcaaaa tcagccagct
     6241 cttcaaagta gcctgtgtct cctgtaaaga caagcacctg cccagttgct ctttccacaa
     6301 tacgaaaagc atagcacacg accgggtgaa ccgtcttaat aaaggtaatg tcaaaaggtc
     6361 caagagcttc aaccctatca acctgatagg caatgccctt tgagacacct ggcaaggtta
     6421 gtttggcaaa ctcggcctca tcttcgtcat gaccgtaaat aggtagtagc cttggcttgc
     6481 caagatgcct tggatagagc tgataataat gacgcaaaac acccaagtct gccacatgat
     6541 ctggatgata atggctaatg ataacagcgt ctaaatccag cggattgatt tctttttcta
     6601 attcgttaag agaacgacta ccagcatcca tcaataattg aaaaccatca tgccctgtca
     6661 caagataggc tgtcgtccca gcatcttgat agggataggc tccccaagag ccaagcgttg
     6721 ttaatttcat cacaaaacct tccttcatgc tttgttctta ttataacaaa aaatagcagc
     6781 aaaaaataag tcctagtgcg caagagctag gacttacagg cttagtattt agctgttggt
     6841 gtttaaaaag ctgtctttat agctaacagc aagcgccgtt gcgatgactg ccttaatagt
     6901 atctcccggg ataaagacaa ggctagcaac gagcgatcta gtgagcggca tgtctgtata
     6961 aaccgctagc caaatagtcc ccaacagatc caccagcagg acaccagaaa taaagattgc
     7021 taaaaaagca agagaccgat accttgctag ccagctgcgg tacaagaatg caaaaaccaa
     7081 tggaacaaag agccaggcca aaacatagcc agccgatggt cccattagga ctggaacagt
     7141 tgttctagag cctgaaaata ctggcaagaa cagaccaatc actagaaaaa gcaggataga
     7201 cagggttcct tttttcccac ctaaaatcaa gccagcaagc atgaccccta agttttgcaa
     7261 aacaatcggc actggaacaa agcctagagg aatcgctgga ataagaccta aaataatgat
     7321 taaggtggtc atcattgcta ccttcactaa gtccttggtt gacaacatat ctcataactc
     7381 ctttgaaaaa taaatatcct gatgcttatg ataggctggg ttaaaagggc taaaacaaaa
     7441 aggacagctg ccgcactcat attcggacct tctcagcagt tgtcggcaat gaccacaaat
     7501 caccggatag gtctccttgt ggtctgtcgg ctcaaaagca tgatcttgaa gcgtgtcatg
     7561 acaatgataa caggcataat aagcctgaca tcgagcacac ttcaagccga caatatccag
     7621 cactgtgtga taatgtacac agcgatactc ctgatcaagc gcgataccaa aacagttcct
     7681 catgtcttat cctcttatta aaaggataaa gcattcgttt tattttgtca acctatattt
     7741 actaataggg ttactaatcg cataagaaga acaccaaaaa agcataaagt agtcccatag
     7801 gcagctgctt tttaccagta ccacacaaat agctatatga ctataaaggt tggcttaaga
     7861 aggttcagat ttaaccgagt gtgggaaaaa gattaccaat ctagctgcca aaatacgggg
     7921 tctcgtttga ctatttttcc ctattgggat ataatgagaa cagaaaaagg gcagttgctc
     7981 taaacaacta ccctatgcag aaccgtttaa gacggtggca tatctttaat t
//
LOCUS       DARYXW010000087         7913 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.087, whole genome shotgun sequence.
ACCESSION   DARYXW010000087 DARYXW010000000
VERSION     DARYXW010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7913)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7913)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7913
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.087"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            75..767
                     /locus_tag="TV191_001613"
     CDS             75..767
                     /locus_tag="TV191_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1508106.1"
                     /translation="MFSGIQLKTARLSRHISQEQLGQLLGVNKMTISNWEKEKNRPNQ
                     KHFEELVSIFQLPAEYFYQENRLLLPYSQLSASNKEKVISYSESLLEQKEKIIALPAK
                     KKTLYPYRVYERLSAGTGYSYFGDGNFDVVFYDEQLDYDFASWVFGDSMEPTYLNGEV
                     VLIKQDSFDYDGAIYAVEWEEQTYIKKVYREENGLRLVSLNKKYPDKFASFDDNPRII
                     GKIIANFMPLDV"
     gene            complement(1143..1619)
                     /locus_tag="TV191_001614"
                     /pseudo
     CDS             complement(1143..1619)
                     /locus_tag="TV191_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515631.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1832..3394)
                     /gene="guaA"
                     /locus_tag="TV191_001615"
     CDS             complement(1832..3394)
                     /gene="guaA"
                     /locus_tag="TV191_001615"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEL1508107.1"
                     /translation="MTEISMLNDIQKIIVLDYGSQYNQLIARRIREFGVFSELKSHHI
                     TAQELRDINPIGIVLSGGPNSVYATDAFGIDPEIFELGIPILGICYGMQLITHTLGGK
                     VVPAGQAGHREYGQSSLRLRSASALFAGTPDEQLVLMSHGDAVTEIPEGFHLVGDSND
                     CPYAAMENTKKRLYGIQFHPEVRHSVYGNDILKNFAISICGGRGDWSMDNFIDMQIAK
                     IRETVGDRKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHGLLRKNEGDQVMEMLG
                     GRFGLNIIRVDASKRFLDLLAGVEDPEKKRKIIGNEFVYVFDDEASKLKGVDFLAQGT
                     LYTDIIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGTALGMPDEV
                     VWRQPFPGPGLAIRVMGEITAEKLETVRESDAILREEIAKAGLERDVWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAQLPWEVLKKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            3681..4379
                     /locus_tag="TV191_001616"
     CDS             3681..4379
                     /locus_tag="TV191_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1508108.1"
                     /translation="MLPAYIKIHDAIKKDIEKEVWTIGSRLPSERDLAEHFEVSRMTL
                     RQAITLLVEEGILERRVGSGTYVASHRVQERMRGTTSFTEIVNSQGRKPSSKLISYQR
                     QLASDTEINQLHLEESDYVIRMERIRYADKVPLVYEVASIPEKFIKNVKKTDITEHFF
                     QTLTSNGYEIGKSQQTIYAKIASERVASYLEVAKGHAILALTQVSFFTDGRPFEYVRS
                     QYVGDRFEFYLENN"
     gene            4591..4923
                     /locus_tag="TV191_001617"
     CDS             4591..4923
                     /locus_tag="TV191_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEL1508109.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEAYEMKLHMYSDYIVRSEIFDDILAKYPSDHYLRDKISI
                     LTSIDNRD"
     gene            4938..6509
                     /gene="ffh"
                     /locus_tag="TV191_001618"
     CDS             4938..6509
                     /gene="ffh"
                     /locus_tag="TV191_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEL1508110.1"
                     /translation="MAFESLTQRLQDVFKHIRGKKTLSEADVQEVTKEIRLALLEADV
                     ALPVVKTFIKRIRERAVGHEIIDTLDPTQQILKIVNEELTGILGSETAELDKSPKIPT
                     VIMMVGLQGAGKTTFAGKLANKLIKEENARPLMIAADIYRPAAIDQLKTLGQQINVPV
                     FDMGTNHSAVDIVANGLAQAKENRHDYVLIDTAGRLQIDEKLMGELREVKALAKPNEI
                     LLVVDSMIGQEAANVAYEFNNQLDITGVVLTKIDGDTRGGAALSIREITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDLLTLIEKASQEYDEKKSLELAAKMRENTFDFNDF
                     IEQLDQVQNMGPMEDLLKMIPGMATNPALANIKVDDKQIARKRAIVSSMTPEEREQPE
                     LLTPSRRRRIAAGSGNSFVEVNKFIKDFNQAKAMMQGVMSGDMTKMMKQMGINPNNLP
                     KNMPNMPGGMPDMSALEGMMGQGGLPDMSALGGDMDMSQLFGGGLKGKIGQFAMKQAM
                     KRQANKIKKAKKKRK"
     gene            complement(6662..7885)
                     /locus_tag="TV191_001619"
     CDS             complement(6662..7885)
                     /locus_tag="TV191_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HEL1508111.1"
                     /translation="MINVAFNSKIGISAQEHDQFVKQHQQVNLLQSSSWAAVKNQWQN
                     ERIGIFQGDNQVASMSLLIKPLPFGMTMIYIPRGPVMDYTNADLVAFTIKTLKAYGKK
                     KRALLIKFDPMILLKQHQLGEKAPDNSKALTIIKHLKRFGAHWTGPTTKLSDTIQPRF
                     QANCYTNADIEASFPKHTKRLMKDARQRGVIAYRGNQSDLHTFADLISLTEKRKGVAL
                     RNEAYFRQLMTTYGDNAYLHLAKVNLPEKLKNYELQLKAVEQELAQTQAHQKKRLARL
                     TDQKQSLQRYLSEFKDFLDKYPDEVVIAGILSISYGNTMEMLYAGMNDDFKKFYPQYL
                     LYPKVFMDAYHDDIAWANMGGIDGSFKDGLTAFKSNFSPTIEEFIGEFNLAISPFYHL
                     ANLLYKIRKQLKHRH"
BASE COUNT         2484 a         1543 c         1489 g         2397 t
ORIGIN      
        1 ttcttataag ctatgttata ctctggtaaa gttaatactt tactagagta tactgacaaa
       61 ggagatttat gctgatgttt tctggtattc aattaaaaac agcacgttta tcaaggcata
      121 ttagccaaga acagctagga cagcttttag gagttaataa aatgactatt tccaattggg
      181 aaaaggagaa aaatagacca aatcaaaagc attttgaaga gcttgtgagc atttttcaat
      241 tacctgctga gtacttttat caagaaaatc gtcttttact tccctatagt cagttaagcg
      301 cctctaataa agaaaaagtt atcagctatt ctgagagctt acttgaacaa aaagaaaaaa
      361 taattgcttt accagctaag aaaaagacac tttaccctta tcgtgtttat gaaaggttgt
      421 ctgcagggac tggctattct tactttggtg atggtaattt tgatgttgtc ttttacgatg
      481 agcagttaga ttatgatttt gcttcatggg tttttggtga ctccatggag ccaacctatt
      541 tgaatggcga ggttgttctc atcaaacagg atagctttga ttatgacggt gctatctatg
      601 ctgttgagtg ggaagaacaa acctatatca aaaaagtata tcgtgaagaa aatggtctgc
      661 gtttggtttc attgaacaaa aaataccctg ataaattcgc ttcctttgat gacaatccgc
      721 gtattattgg aaaaatcatt gccaacttta tgcccttaga tgtataagcc tttgtattag
      781 cttaaaagca tgactgttgt acaaccaaac tcattgcatg acattggtgc attatttttg
      841 aagtggcttc tacttctttg atttactttt ctgcattaaa aagcccatta aaggtttttg
      901 aaacttatta cttagacaaa ggctctatta aaaatcataa ccaaccggtg gtggtttatt
      961 tgtcatgtac cttgcatttt gtgacagact tcataaaacg aacaaaacac atcgctaaaa
     1021 gattttacca tcttaaagtt atgtgttttt tgtataaaaa cttatctata tgcttgatta
     1081 accaactgag ataaatagat tattatttca tagagaagtt tgttatctaa tccaaataat
     1141 cgtattatcc tcttaagttc ctcaacatta taaccatcac aatctgttgg cagtttattt
     1201 ttttcaagcc acttatcaac cactgctatt cccaaagaaa ttgaaaaatc tttttcttta
     1261 tcaaacttac acaattccac tgccaaagtc aatacaaaat tcctgtgaat attatcgtaa
     1321 ttttcatcaa ataattgcct ttccaaaccc acaatagata gccgactaaa tatgtatctc
     1381 cctatttctt cgtcaatacc ttcagtagcc ttaatagctt cttggacaac attattccag
     1441 aaagcatttt tattacgctc ttctataaaa gttttaagtt tcattttgaa aatatcagta
     1501 atttgaccaa ctgctttatc aataacctat gaaacaatat tcttcatcat tatgattttc
     1561 tcctcgtata cataaataat tgtatctttg ctatataatt gtggtatctc ttcaatcaac
     1621 caatattgtt cttaaactat tccctcaaaa gccttccacc aaaacgatgg aaggctttta
     1681 aaccattcac ctaaattcaa caactccctt ttgaacttgc tattttagct ttttagtatc
     1741 aaagcagtat cactcaagag ttttttgttt ccacaaaccg caaaaaccca ctgttttcaa
     1801 cactttcatg gcagtaatat atttgcttct gtcactccca ctcaacggtt gctggtggtt
     1861 tgctggtgat gtcgtagaca atgcgattaa cgtggtcgac ttcattgaca attcgaactg
     1921 agattttctt tagaacttcc caaggcaatt gggcaaagtc tgctgtcata ccatcaattg
     1981 aggtgatagc acgaatagcg atggtatagt cataggtgcg accatctccc ataactccga
     2041 cggaacgaac acctgtgtta actgtaaaat attgccacac atcacgctca agtcctgctt
     2101 tagcaatttc ttctcgaagg atagcatctg actcgcgaac tgtttcaagc ttttctgctg
     2161 tgatctctcc catgacgcga atggcaaggc ctgggcctgg gaaaggctga cgccagacga
     2221 cttcatctgg cataccaagg gccgtaccaa gagcacgaac ctcatcctta aagagtgtat
     2281 tgaggggttc gattaattca aactgcatat cctctggcag accaccaaca ttgtggtgag
     2341 attttatcgt ttgagcagtt tctgttccag attcaatgat gtctgtgtaa agcgttcctt
     2401 gtgcaaggaa gtcaacgccc ttaagcttgc tagcctcgtc atcaaagacg taaacaaact
     2461 cattaccgat aattttacgt tttttctcag gatcctcaac gcctgcaaga agatctaaaa
     2521 agcgctttga ggcatcaaca cgaataatat tgagaccaaa tcttccacca agcatttcca
     2581 taacttggtc accttcattt ttacgaagaa gtccatggtc aacaaagata caggttaatt
     2641 gatctccgat agctttttgt aaaaggacac caacaactga agaatcaaca ccaccagaca
     2701 aacctagcaa aaccttacga tctccgactg tttcgcgaat tttagcaatt tgcatgtcaa
     2761 taaaattatc cattgaccaa tcaccacgtc caccacagat agagatagca aagttcttca
     2821 aaatatcatt accatagaca gagtgtctta cctctgggtg gaattggata ccgtagagcc
     2881 tcttttttgt attttccata gcagcgtaag ggcaatcgtt agaatctcct acaagatgaa
     2941 agccctctgg gatttctgta acagcatcac catgactcat caaaacaagc tgctcatctg
     3001 gagtgcccgc aaataatgct gatgcagaac gtaaacgtaa tgatgattga ccatattctc
     3061 ggtgacctgc ttgaccagct gggactacct tacctcctaa ggtatgtgtg attagctgca
     3121 tgccatagca aatccctaaa attggaatcc ctaattcaaa gatttcagga tcaataccaa
     3181 aggcatcagt tgcataaaca gaatttggcc caccagacag gacaatcccg attggattga
     3241 tgtcacgaag ctcttgcgca gtgatgtgat ggcttttgag ctcagaaaaa acaccaaact
     3301 cccgaatacg tcttgcaatc agttgattgt actgactacc ataatcaaga acgataattt
     3361 tttgaatatc attcaacatt gaaatttcag tcattataac cctttcatta tataccagaa
     3421 ccttgttagc tgatagtttt caattaattg tagcatattt tcactaaaaa ggcattagct
     3481 tttcaggtga tgtgatgaaa aaataagctt tttgcagaga tattaaaatg aatgacctca
     3541 actatcttat gtatgactac tattgtcagt cttagcatga aaaagctgat tgatgatgag
     3601 tgtttttggt aataattggg ctgctattta ggctgaaaat atgataaaat aaaaccatca
     3661 tcaccctcaa ggagtaaagc atgctgccag cttatataaa aattcatgac gctattaaaa
     3721 aagacatcga aaaagaagtt tggactattg gtagtcgcct gccaagcgaa cgagatttag
     3781 cagaacattt tgaggtcagt cgcatgacgt tgcgtcaggc aataacactg cttgtagagg
     3841 agggaattct agaaaggcgt gttggtagtg gtacttatgt tgccagccat cgcgtacaag
     3901 agagaatgcg tgggaccact agctttacag agatcgtgaa ttctcaggga cgtaagccat
     3961 cttcaaaact gatttcctat caacgtcagc tagcaagtga tacagaaata aatcaattgc
     4021 acttagaaga atcagattac gttattcgaa tggagcgcat tcgttatgca gataaggttc
     4081 ccttagttta cgaggtagca tctattcctg agaaatttat taaaaatgtc aaaaaaactg
     4141 atattacaga gcactttttc caaaccctaa cctcaaacgg ttatgaaatc ggcaaaagtc
     4201 aacaaaccat ttacgcgaaa atagccagtg agcgtgtcgc ctcttatcta gaggtcgcta
     4261 aggggcatgc tattttagca ttgactcagg tttccttttt tacagacggt aggccctttg
     4321 aatatgtgcg tagccaatat gtaggtgatc gctttgaatt ttatttagaa aataattaat
     4381 cataagcaat gatgtttaaa taacattgat aggaagtggc tcaccacttc tttttttcaa
     4441 cacttgtcaa gtatatcaat atttcaagaa cagttattaa aacaagctac tattatcctc
     4501 atttttgctc taagaaagct tcctgataaa aggctgatcg ctatcattta ccactgttaa
     4561 aaatgctcat gatgtgataa aatgaagatt atggaaattg aaaaaacaaa ccgaatgaat
     4621 gctctttttg aattttatgc tgccttattg actgataaac agatgaacta tatcgagctc
     4681 tattacgctg atgattatag tctggctgaa attgctgaag aattcggtgt cagccgccaa
     4741 gcagtttatg ataatattaa gcgcactgaa aaaattctgg aagcctatga aatgaagctt
     4801 catatgtatt cagattatat tgtacgtagt gaaatatttg atgatattct tgcaaaatat
     4861 cccagtgacc actatttacg tgacaaaatt tccattttaa ctagtattga caacagagat
     4921 taagaggagt tatagctatg gcatttgaaa gcctaaccca acgtttacag gacgttttta
     4981 agcacattcg tggtaaaaaa accttatctg aagccgatgt tcaggaagtg accaaggaga
     5041 ttcgtctagc cttattagag gcagatgttg cacttccagt tgttaagacc tttatcaagc
     5101 gtatacgtga gcgagctgtt ggccacgaaa ttattgatac ccttgatcca acgcaacaaa
     5161 tacttaaaat tgttaatgag gaattaactg gtatcttagg atcagaaacc gcggagcttg
     5221 ataaatcacc taaaatccct actgtcatca tgatggtggg cttgcaggga gctggtaaaa
     5281 cgacctttgc aggaaaatta gccaataagc tcatcaagga agaaaatgct cgtccattga
     5341 tgattgcagc agacatctat cgtccggctg ctattgacca gttgaaaacc ttgggacagc
     5401 aaataaatgt tcctgttttt gatatgggga caaatcattc agcagttgat attgttgcca
     5461 atggtttggc acaggcaaaa gagaaccgtc atgactatgt tttgattgat acggcaggac
     5521 ggttacaaat tgatgagaaa ctaatgggcg agcttcgtga ggttaaagca ctagctaaac
     5581 caaacgaaat ccttcttgtt gttgacagca tgatcggaca agaagctgcc aacgttgcct
     5641 atgaatttaa caatcagctc gatatcactg gagtagtgtt aacaaagatt gacggtgata
     5701 ctcgtggtgg tgcggccctt tctatacgtg aaataactgg taagccaatc aaatttaccg
     5761 gaactggtga aaaaatcacc gatattgaaa ccttccatcc agaccgtatg tcaagtcgta
     5821 tcttgggaat gggagacctt cttaccttga tcgaaaaagc aagtcaggaa tatgatgaga
     5881 aaaaatcatt agagcttgcc gcaaaaatgc gtgagaatac ctttgatttt aatgacttta
     5941 tcgagcaatt agaccaagtg caaaacatgg ggccaatgga agatctgtta aaaatgattc
     6001 caggtatggc aactaatcct gctctagcca atattaaggt tgacgacaag caaattgctc
     6061 gcaagcgtgc tatcgtttct tctatgacac ctgaggagcg tgagcagcca gagcttttaa
     6121 caccaagtcg ccgccgtcgc attgcagctg gatcaggtaa tagtttcgtt gaagtcaaca
     6181 aatttattaa agattttaac caagccaaag ccatgatgca gggtgtcatg tcaggtgata
     6241 tgactaaaat gatgaaacaa atgggaatca accctaataa cctccctaaa aacatgccaa
     6301 atatgccagg aggcatgcct gatatgtctg cccttgaagg aatgatgggg caaggtggtt
     6361 tacctgacat gtctgcattg ggtggtgata tggatatgag ccagctcttt ggaggtggtc
     6421 taaagggtaa gattggtcaa tttgccatga agcaggccat gaagcgtcaa gctaataaga
     6481 ttaaaaaggc caagaaaaaa cgaaaataga ctaaaagaat ggttgccttg tattctgcct
     6541 ctaatcgtta gatgctattc taatttggag tgcaggtcag tagcgaccat cttttttata
     6601 aatacaatca ctagatcttt ggttctaacc attaaacatg atatcatttc actattagct
     6661 gttagtgcct gtgctttaat tgctttctga tcttatatag caaattagcc aagtgataaa
     6721 aaggactgat tgctaggttg aattctccaa taaactcttc gatagttgga ctgaaattgg
     6781 acttaaatgc tgtcaatccg tccttgaagg agccatcaat gccgcccata ttcgcccaag
     6841 ctatatcatc atgataggca tccataaaga ctttaggata aagcaggtac tgaggataaa
     6901 actttttaaa gtcatcattc atgccagcat agagcatttc catcgtgttg ccatatgaaa
     6961 tcgataaaat gcccgcaatg acaacctcat ctggatattt atccaagaag tccttgaatt
     7021 ctgatagata acgctgaagc gattgctttt gatctgttag tctagccagt cgcttttttt
     7081 gatgcgcttg cgtttgagca agctcttgtt caacagcttt cagctgaagc tcgtaattct
     7141 tgagtttttc tggaagatta acctttgcta aatgcaaata agcattgtcg ccataagtcg
     7201 tcatcagctg tctaaaataa gcttcgtttc ttagagcaac tccttttctc ttttcagtta
     7261 aagagataag gtcagcaaat gtatggagat cagactgatt acctcgataa gctatcacgc
     7321 cacgttgcct agcatccttc atcaatcgct tggtatgctt aggaaaggac gcttcaatat
     7381 cagcattagt gtaacaattt gcttgaaaac gcggctgaat agtatcagat agcttggttg
     7441 ttgggcctgt ccaatgggca ccaaatcgct ttaaatgctt aataatggtc agagccttgg
     7501 aattatcagg tgctttctca ccaagctgat gctgctttag cagaatcata ggatcaaatt
     7561 taatcaaaag agctcttttt ttcttaccat atgccttcaa ggttttaatc gtaaatgcca
     7621 ctagatcagc attggtatag tccatcactg gacctcttgg aatataaatc atcgtcatac
     7681 caaacggcaa aggcttaatc agcaaggaca tagaagccac ctgattatct ccctgaaaaa
     7741 taccgatgcg ttcattttgc cactgatttt taacagctgc ccatgagctg ctctgcaaga
     7801 ggttaacctg ctggtgctgt ttgacaaatt ggtcatgctc ttgagctgaa ataccgattt
     7861 ttgaattaaa agctacattt atcatcatat ttcctcatct ttaagtatct aaa
//
LOCUS       DARYXW010000088         7866 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.088, whole genome shotgun sequence.
ACCESSION   DARYXW010000088 DARYXW010000000
VERSION     DARYXW010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7866
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.088"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            53..2590
                     /locus_tag="TV191_001620"
     CDS             53..2590
                     /locus_tag="TV191_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL1508112.1"
                     /translation="MKQHQRFLSLVGLLLACNLALTACQTHSQKGHSQEPKKHQKATK
                     KKKQKSSKTAKKRERHQVPGIDVPTDDGFLLTSESQIERKTDTGIIVKHGDHKHFFFY
                     SDLKGTKWAYLIPKDYKEAQPASNQAARSGSVVSTGHAGDGYVFNPADIVAEDAYGYT
                     VRHGDHYHYILKSSLPSATINHIASTTPHFPSTPPSIHQQGGIPGIDFKTSDGFLFDG
                     TNISGVTDTGILVKHGNHLHPISFEDLKRSKWAYLVEQYKKKDHTKPQEGDYRAYIAY
                     LAKELKVDQARIKQVNVDGQVGFEYPHEDHTHVIWLKDIDLSKPFKTPEEQILKKIDG
                     ETFEQRKERLIKEFMDRFKVRREDISIEGNYMTISHGDHAHIYKIDPELPDDPERNVK
                     TESTNLEVETQLVYGPFYTENSSENLTRDGVYKKYHPEGIKNIKNFIHVLFSTNSEYG
                     DIEVNGIKTKRVHYLVRKDLDWKDLNIQRPEAIKHEGRIFKGWSAELPTAGKMDREHQ
                     RFYVDFDKVRKQPTKAVYGPGDDVSDLDLENYVPVWFTTIFNGRLKLNGVTQGGFFYN
                     VRSGLTWKEAKEQGLVIPEPVPDPGYEFIEYRSGVNLANNFNLTDFAKRFSITQNEND
                     KVAFTGLFSAAFGTTAPYIGPYIAVNPDKPTDLEDPSRHPNYYFHDPRHYVAVAFKAG
                     EGGQLISRAGKGKTAVYLVRKGHSLHTAGILPPSVQPDAGYKRDYNKPIISTEEYDKE
                     VTEDIVYNVNFDKITNNDVTGNSNHSGNTWLPGDPLPKEPQTPNHTGSTGSWLEEFVA
                     PVSDSDEDDLLAPDPELVGKTPVSDKPASYFLGESETASSTSVASNS"
     gene            complement(2788..3216)
                     /locus_tag="TV191_001621"
     CDS             complement(2788..3216)
                     /locus_tag="TV191_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL1508113.1"
                     /translation="MKLLDKTVHFSGAKLALISNGKILTILRDAIPTIPYPNMWDLPG
                     GGRENAEAPFDCASRECYEELGLALTKDAVVWERVYPGLVNPDSQSVFLVALMNQDMI
                     DHIAFGDEGQGYQLMAIDDFLADDRVIPQLKARLADYLRK"
     gene            complement(3233..3577)
                     /locus_tag="TV191_001622"
     CDS             complement(3233..3577)
                     /locus_tag="TV191_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009910982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEL1508114.1"
                     /translation="MLHEMMLTPRPFAMIEAGVKTIELRLNDEKRQAIKVGDWICFYC
                     TEDHSHILQAEVVGLHYFDDFAKLYQALPLEKCGYRNEELALARPEDMEQYYSKEQQA
                     QYGVVGIELRLC"
     gene            complement(3579..4049)
                     /locus_tag="TV191_001623"
     CDS             complement(3579..4049)
                     /locus_tag="TV191_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEL1508115.1"
                     /translation="MAKYGFLSVLEEEMDKHFHYDYAMDWDKKNHAVEITLVLEAQNQ
                     SAVETIDDQGQLSKEDIVFEDYVLFYNPEKSQFQAADYLVAIPFEPKKGFSREFLAYF
                     AQFLNDVAIEGHSDLMDFLADDSKLDFSLEWNEEAFEEGQVGLEETELYSYPRY"
     gene            4198..5934
                     /gene="pabB"
                     /locus_tag="TV191_001624"
     CDS             4198..5934
                     /gene="pabB"
                     /locus_tag="TV191_001624"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEL1508116.1"
                     /translation="MHIKTIIDFKELGQRYIFQAPIVELVAKQIDQVGQVLEQVNQFQ
                     DLGYYVVGYLSYEAAACFDKKLTTHNKRLGQEYFAYFTVHDSCQLEDFPLYHDSMTIP
                     NSWTSATQEEAYQEAIAQIHQEMRQGNTYQVNYTIQLSQRLNAKDSLAIYHQLVIEQA
                     AGYNAYIAHDDFAVISASPELFFKQEKNQITTRPMKGTTKRGYNLELDQQEHDWLQAD
                     PKNRSENMMIVDLLRNDMNKICQTGSVTVTQLCQLEQYSTVWQMTSTIVGMLQDQCRL
                     YDILQALFPCGSITGAPKVSTMAIINRLEPKPRGVYCGSIGICLPDGRRVFNVAIRTI
                     QLSYDQAIYGVGGGITWESCWQDEFEEIKQKSSFLNRQSIDFTIKTTAKVEQQSLIYL
                     DQHLNRLREAARYFAYPYDEELLTDRLQAYLKGKDSSPYRLTIAIAKDGQISLTDQSL
                     EPLQKDFLKARLVRQSSDVKKLPFTYFKTSHRPHLSVKPYEQVFVAADGTLLETSIGN
                     LFVQIEQTLYTPPVSAGILPGIFRQELLRQGLAQEKELKLSDLDKAEAIFGGNAVRGL
                     YSLTIEDTTLPQ"
     gene            5975..6583
                     /locus_tag="TV191_001625"
     CDS             5975..6583
                     /locus_tag="TV191_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEL1508117.1"
                     /translation="MILLIDNYDSFTYNLAQYLSAFDQTIVLTNQDPKLFDLAKQADA
                     IVLSPGPGWPKAANQMPSLIRAFYDQKPMLGVCLGHQAIAEALGGRLRLAKRVMHGKQ
                     SILERQAPAKLFQQLPKQLTVMRYHSIVVDDLPADFVITARDFEDNEIMAFEHRQLPL
                     FGLQFHPESIGTADGRTMIANFMAVVKKHHSQQKQGREEYNA"
     gene            6576..7847
                     /locus_tag="TV191_001626"
     CDS             6576..7847
                     /locus_tag="TV191_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEL1508118.1"
                     /translation="MPDNLAIRMRPRTITEVIGQQHLVGEGKIIDRMVKANRLASMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATIDNKKRLQEIAEEAKFSGGLVLLLDEIHR
                     LDKSKQDFLLPLLEHGHIIMIGATTGNPFFSVTPAIRSRVQIFELEPLSPEEIKQALK
                     LAITDKERGFAFDVTLDEAAFDFIATATNGDLRAAYQSLDLAVMSTQPDTEGIRHISL
                     NTVENSLQRSYITMDKDGDGHYDILSALQKSIRGSDVNASLHYAARLIEAGDLPSLAR
                     RLTIIAYEDIGLANPEAQIHTVTALEAAQKIGFPEARILIANVVIDLALSPKSNSAYM
                     AMDAALADLRQHGHLPIPRHLRDGHYAGSKELGNAQHYLYPHAYPEKWVKQQYLPDHL
                     VKKNYFNPNETGKYERALAANKARIDKLSSS"
BASE COUNT         2340 a         1863 c         1637 g         2026 t
ORIGIN      
        1 gtaataatat taactggtta agttaattgt tggaaggagt tgataactaa ccatgaaaca
       61 acatcaacga tttttatccc tcgttggact gctgttagcc tgcaaccttg ccttaacagc
      121 ctgccaaacg cattcgcaaa agggacattc tcaggagcct aaaaagcacc aaaaggctac
      181 gaaaaagaaa aaacaaaaaa gcagtaagac tgcgaaaaaa agagaacgtc accaagtccc
      241 tgggattgat gtcccaactg atgatggctt tttattgacc agcgaatcgc aaattgaacg
      301 caaaacagat acaggtatca ttgtgaagca tggcgatcac aagcatttct tcttttactc
      361 agatttgaag gggacaaaat gggcttacct gattcctaag gattacaagg aagcacagcc
      421 tgcttctaac caagcggcaa ggtctggatc agtagtctca actggtcatg ctggagacgg
      481 ctatgtcttt aatccagctg acattgttgc tgaggacgcc tatggctaca ctgttcgtca
      541 tggagatcat taccactata tcctcaaatc aagcctgcca tcagcaacca tcaaccacat
      601 cgcatcaacc acacctcact tcccatcaac accacctagc attcatcagc aggggggtat
      661 cccaggaatt gacttcaaaa ctagtgatgg cttcttattt gatggcacca acattagcgg
      721 tgtcactgac actggaatcc tggtgaagca tgggaaccat ttgcacccta ttagctttga
      781 ggacttaaag cgtagcaaat gggcttattt agtggagcaa tataagaaaa aggaccacac
      841 caagcctcag gaaggagact atcgcgccta tatagcttat ctcgccaagg agctaaaggt
      901 agatcaagca cgcattaagc aggtgaatgt agacggtcag gtcggctttg aataccctca
      961 tgaggaccac acgcacgtca tctggctaaa ggatattgat ctttctaagc catttaaaac
     1021 tccagaagaa cagatcctca aaaagataga cggagaaacc tttgaacagc gcaaagaaag
     1081 actcatcaaa gaatttatgg atcgcttcaa ggttcgtcgt gaggacatct caattgaggg
     1141 caactacatg accattagtc atggggacca tgctcacatc tataagattg acccagaatt
     1201 gccagatgat cctgagcgca atgtcaagac agaatcaacc aatctagagg tcgaaactca
     1261 gctcgtttat ggtcctttct atacggaaaa ttcatctgaa aatctaacac gtgatggggt
     1321 ctataaaaaa tatcacccag agggcatcaa aaacatcaaa aactttatcc atgtgttgtt
     1381 tagtacaaat agtgaatacg gcgacattga ggttaatggc attaaaacta aacgtgtgca
     1441 ctatttggtt cgtaaggatt tggactggaa ggatttgaac attcagcgtc cagaggcaat
     1501 caagcatgag gggcgtatct ttaagggctg gagtgctgag ttgccaacag ctggcaagat
     1561 ggacagagaa catcaacgct tctatgtaga ttttgataag gttagaaagc agcctaccaa
     1621 ggctgtctac gggccaggtg atgatgtttc agaccttgac ttagaaaatt atgttcctgt
     1681 ctggttcacc acaatcttta atgggcgatt gaagcttaac ggcgtgactc aaggaggctt
     1741 cttctacaat gttcgtagtg gtcttacctg gaaggaagct aaggagcaag gacttgttat
     1801 ccctgagccc gtcccagatc caggctatga atttattgaa taccgcagtg gagtgaacct
     1861 tgccaataac tttaatctaa ctgattttgc taagagattt tctatcacac aaaatgaaaa
     1921 cgataaggta gcctttactg gcctattctc agcagccttt ggaactactg ctccttatat
     1981 tggaccttac atcgctgtta atcctgacaa gccaactgat ctagaggatc ctagcagaca
     2041 ccctaattat tacttccacg atccgagaca ctatgtagcc gttgccttta aggcaggaga
     2101 gggcggacag ctgattagcc gagctggtaa gggtaagact gccgtttacc ttgttcgtaa
     2161 gggacactca ttacatacag ctggtatcct accaccatca gtacagccag atgccggcta
     2221 caagcgtgat tacaataagc ctattatttc aactgaggaa tatgataagg aagtcactga
     2281 ggatattgtt tataacgtca actttgataa aataaccaac aacgatgtta caggtaatag
     2341 taatcactca gggaatacct ggctaccagg tgatccacta cctaaggagc ctcaaactcc
     2401 taatcacact ggcagcactg gaagctggct agaagaattt gtagcgcccg tttctgactc
     2461 cgacgaggac gacctattag cacctgaccc tgagcttgtt ggtaagacgc cagtaagtga
     2521 taagccagcc agctattttt taggtgagtc agagacagct agcagcacat cagtagctag
     2581 caacagctaa gccatagcag gactgattga taatatcaac tactcagctg atctggccta
     2641 ccagattaaa gacttagcca ccccaaaaac aaagacgatt gatcctagcc acatgtgggc
     2701 agaggtcaat cgtctttttg attctggtcg tagctatcac atagtagtgg tgtttgctga
     2761 tctgtttagt gtaccagcta agtctgccta tttccttaaa taatcagcta agcgagcctt
     2821 tagctgagga atgacccgat cgtctgctaa aaagtcatca atagccatca gctgataacc
     2881 ctgcccctca tcaccaaaag caatatgatc tatcatgtcc tgattcataa gagccaccag
     2941 aaagacagat tggctgtcag gattaacaag ccctggataa accctttccc aaacgacagc
     3001 gtccttagtc agtgccagac ctaactcctc atagcactca cgtgacgcac aatcaaaggg
     3061 agcttcagca ttttcacgac cacctcctgg taaatcccac atattagggt aaggaatcgt
     3121 tggtatcgcg tcacgcaaga tggtcaaaat cttaccgtta ctgatcaagg ctaactttgc
     3181 accagaaaaa tggactgttt tatctaaaag cttcatgact agatctcacc aatcaacata
     3241 gccttagctc aataccaaca acgccatatt gggcttgctg ctctttgctg tagtactgtt
     3301 ccatatcctc cggccgagcc agtgccaatt cttcattacg ataaccacat ttttctaaag
     3361 gcaatgcttg gtaaagctta gcaaagtcat caaaataatg caaccctacg acctctgctt
     3421 gcagaatatg gctatgatcc tctgtacaat aaaagcaaat ccaatcccct accttaatag
     3481 cctgcctttt ctcatcattt aaccgtagtt caatagtctt cacacccgcc tcaatcatag
     3541 caaatggtct tggtgtcagc atcatctcat gtagcatctt aatacctcgg atagctataa
     3601 agctctgttt cctctagtcc tacctgccct tcctcaaagg cctcctcgtt ccactctaga
     3661 ctaaaatcaa gcttgctatc atctgctaag aaatccatca aatcgctatg cccttcaatg
     3721 gcaacatcat tgagaaactg ggcaaaatag gctaaaaatt cacgagaaaa gccctttttt
     3781 ggctcaaatg gaatagccac cagatagtct gctgcttgaa actgtgattt ctccggattg
     3841 taaaataaga cataatcctc aaagacaatg tcttccttgc tgagctgtcc ttggtcatca
     3901 atggtttcaa ctgctgactg attttgagcc tctaaaacaa gggtgatttc aaccgcatga
     3961 tttttcttgt cccaatccat agcatagtca taatgaaaat gcttgtccat ctcttcttct
     4021 aatactgata aaaagccata tttagccatg ctcttgttcc tttttctaaa taatatccgc
     4081 tactattgta gcataaatca agaagccctg ctctcttgta ttgttgatgg ttgctaacag
     4141 gcttcttttc aaccctccta atcagtctga aaagcgcatt tatgatataa tcaagctatg
     4201 catataaaga cgattattga ttttaaggag ctgggacaac gctatatatt tcaagctcct
     4261 atcgtggaat tagtagctaa gcagattgat caggtgggac aggtccttga gcaggtcaac
     4321 caatttcaag atctgggcta ctatgttgtg ggctacctca gctatgaagc agcagcctgt
     4381 tttgacaaaa agctaacaac acacaataaa agacttggtc aggaatattt tgcttatttt
     4441 acagtgcatg acagctgtca gctcgaggac tttccgctct accacgacag catgacgatt
     4501 ccaaacagct ggacaagtgc tacacaagag gaagcctatc aagaggctat tgcacagatt
     4561 catcaggaga tgaggcaggg caatacctat caggtcaact ataccattca gctcagccaa
     4621 aggctaaacg ctaaggacag cttggccatt tatcatcaat tggtcattga acaggcagct
     4681 ggatacaatg cctacattgc tcacgatgac tttgctgtca tttcagccag tcctgagtta
     4741 tttttcaagc aagagaaaaa ccagatcacc acacgcccca tgaaaggcac aaccaagcgt
     4801 ggttacaatt tagaactaga tcaacaagag catgactggc tacaggccga tcctaagaac
     4861 cgttcagaaa acatgatgat cgttgattta ttacgcaatg atatgaataa gatctgtcaa
     4921 actgggagtg tcacagtcac acagctctgc caattggagc aatattccac cgtttggcag
     4981 atgacctcta ccattgtcgg catgctgcag gatcagtgtc gtctttatga tattttacag
     5041 gcactctttc cctgtggctc catcacagga gctcctaagg tgtctacaat ggctattatt
     5101 aaccgattag agcctaagcc aaggggcgtt tactgtggca gcattggtat ttgcctgcct
     5161 gatggcagac gtgtcttcaa tgtcgctatt cgaacgattc agctcagcta cgatcaggcc
     5221 atctacgggg taggcggtgg gattacctgg gaaagctgct ggcaggacga atttgaagaa
     5281 atcaagcaaa aatcttcctt tctgaaccgt caaagcattg atttcaccat caaaaccact
     5341 gccaaggtcg aacaacaaag cctaatatat ctagaccagc acctcaacag actaagggag
     5401 gcggcgcgtt attttgccta cccctatgac gaagagcttc tgacagatcg tttgcaagcc
     5461 tatctcaagg gaaaggacag cagcccctat cgtctcacta ttgctattgc taaggacggg
     5521 cagattagcc ttacagacca aagcttagag ccgcttcaaa aagacttttt aaaggcacga
     5581 ttagttcgcc aatcaagcga tgtcaaaaag cttcccttta cttattttaa aaccagtcat
     5641 cgaccacatc tgagcgtcaa gccttatgag caagtctttg ttgctgctga tgggaccttg
     5701 cttgaaacct ctattggtaa tctttttgtg caaatcgagc agacccttta tacaccgcct
     5761 gtatcagccg gtattctacc aggcattttc cgtcaagaat tactaaggca gggactggct
     5821 caggaaaaag agctaaagct ttcagattta gacaaggccg aagccatttt tggtggcaat
     5881 gctgtccgag gactctactc actaacaatt gaggacacca ctctgcctca atagtaccag
     5941 gctgatccct cagcactact agatgaagga ccttatgata cttttaattg ataactacga
     6001 ttcatttacc tataatctgg cccaatacct cagtgccttt gatcaaacga ttgtattgac
     6061 caatcaggat ccaaaactat ttgaccttgc gaagcaggct gacgccatag tcctctcacc
     6121 tggacccggc tggcccaaag ccgccaatca gatgcctagc ttgattaggg ccttttatga
     6181 ccaaaagcct atgcttggcg tttgccttgg ccaccaagct atcgctgagg ctctaggtgg
     6241 caggctacgc cttgctaagc gcgtcatgca tggcaagcaa agtatacttg aaagacaagc
     6301 accagctaag ctctttcaac agctgccaaa gcaattaacc gtcatgcgtt accattctat
     6361 tgttgttgat gacctgccag ctgactttgt aattaccgca agagactttg aggacaatga
     6421 gattatggcc tttgaacaca gacagctgcc actgtttggc cttcaatttc acccagaaag
     6481 catcggaaca gctgacggta ggacaatgat cgcaaacttt atggctgttg ttaaaaagca
     6541 ccacagccaa caaaagcaag gaagggagga atacaatgcc tgataatcta gccatcagaa
     6601 tgcgccctag aaccattaca gaggtcatcg gccagcagca tctggtcggg gagggaaaaa
     6661 tcattgaccg catggtcaag gccaatagat tagcctcaat gattctttac ggacctcccg
     6721 gtattggaaa gacatcaatt gctagtgcta ttgctggaac aaccaagtac gcctttagaa
     6781 ccttcaatgc taccatagac aataaaaaac gcctccaaga aatcgctgag gaagctaagt
     6841 tttcaggtgg acttgtgctt ttgcttgatg aaattcaccg attggataag agtaagcagg
     6901 actttttact accactttta gagcatgggc acattattat gattggtgct accacaggga
     6961 atcctttttt ctcggttact ccagccatca gaagtcgagt ccagattttt gagctggagc
     7021 ccctatcacc tgaggagatc aagcaggcgc ttaagcttgc catcactgat aaggagagag
     7081 gctttgcctt tgatgtgacc ctagatgagg ctgcttttga ctttattgcg acagcgacaa
     7141 atggagatct ccgagccgcc taccaatccc ttgatctagc tgtcatgtca acccagccag
     7201 ataccgaggg tatccgtcat atcagcttga atactgttga aaattctttg cagcgcagct
     7261 acatcacaat ggacaaagat ggcgacggac attatgacat actatctgcc ttgcaaaaat
     7321 caatccgagg atctgatgtt aatgctagct tgcactatgc tgcaaggctt attgaggcag
     7381 gcgatcttcc gagtcttgct agacgcttga ccattatcgc ctatgaggac ataggtcttg
     7441 ccaatccaga agctcaaatc cataccgtca ctgcacttga ggccgcccag aaaattggct
     7501 tcccagaggc gcgtatcctc attgccaatg ttgtgattga tctagcactg tcaccaaagt
     7561 ccaattccgc ctatatggct atggacgctg ctctcgctga tttacgtcaa catggccatc
     7621 ttcccattcc tagacacctg cgtgatgggc attatgccgg cagcaaggag ctaggcaatg
     7681 ctcagcacta cctttaccct catgcatatc cagaaaaatg ggtcaagcag caatatctcc
     7741 ctgatcactt ggttaagaaa aattacttca acccaaatga aacaggaaaa tatgaaagag
     7801 ccttagccgc caataaagcg cgaattgata agctttctag cagctagcct aaagaaaaaa
     7861 acaaga
//
LOCUS       DARYXW010000089         7718 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.089, whole genome shotgun sequence.
ACCESSION   DARYXW010000089 DARYXW010000000
VERSION     DARYXW010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7718)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7718)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7718
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.089"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            <1..406
                     /locus_tag="TV191_001627"
     CDS             <1..406
                     /locus_tag="TV191_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEL1508119.1"
                     /translation="GRGFYKKYMNAYGQVARLHSQQWYTDVVHLPVEFPMSADGHRPV
                     SERYRTLSDKEIREGFLSIGKTPELVSGSQVERLRKIINLYDLPVVVPIDEAVTQAEE
                     QIRTNREAVSKRIIEQYKEPSLKEKIKFISEF"
     gene            415..1086
                     /locus_tag="TV191_001628"
     CDS             415..1086
                     /locus_tag="TV191_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1508120.1"
                     /translation="MISFKNISKTYQVGDQEVKVLDDVSFTIEKGRFTVILGPSGSGK
                     STLLNLLGGMDRASKGTFIFEGKDITALNDKALSDYRKEVVGFVFQFYNLIPSLTALE
                     NISIAAQLTGNTAQSEVLLDKVGLSHRKNNFPSQLSGGEMQRVSIARALAKKPKLLLC
                     DEPTGALDSKTGQHIMQLLQEASKDEDVAVVLVTHNTEFKAFGDTIIYLKDGKISSID
                     HKQSV"
     gene            1103..3376
                     /locus_tag="TV191_001629"
     CDS             1103..3376
                     /locus_tag="TV191_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1508121.1"
                     /translation="MKYLNLKLRRDLKHHWQQFFSVFLMSLLSVLIFVGLQGAWHGLE
                     KSLDNYISTSHLPTVWVQATNLTKQDIEKIEALNQVSKVRPKIRVTAAIDSDSDLEHY
                     LTLDSLQSTSDQVTRVVAGEAFSTKETDKVWLNKEYADANHLSLGDKISLTLSGQSIS
                     VTLAGLVQSADRIYFTGSLEYIAPNYDNYAYGYISKKSLAKLLQTQLPDNMVDIYASS
                     DDLRDDIENILGNKLVSYYNQTTLTDVSEAVDRVGQIRNLSYLFSFIFILLAILSMFT
                     TIRRLIESQTKEIAIIKALGYSNIQVSGHYISFGLLVGTLGALSGLLVSPAMSWFVLE
                     TQKRMFSLPKWEIAYSLSSLVVALLVVMICVTSAYFASRKAIKGLPAVFLRGKNRDVK
                     HILLEKIKPLWRSISDEAKWAIRDALTHRIRILMGIIGVAGSMMLLIAGIGMPISMNH
                     LVDKAYNKDFSYSKRLTVSDYESANKAYKGQWVQINQAHFSKDDGYNRLLIIISKGSL
                     VNATTEDGDKIKEGGLYVTNSFAKLANIKVGDKLSVTPYQDKHQYTFSVKGILTSETN
                     QGAYIMADTFKKAGGAFHPHTLLVDKQVSASTIAQDQNVLTVIDKSSQESNAYDLVNS
                     LMSVFLMIIGFALLLVIVVLYNLGSLNFVERTRDYATLQVLGFSKRNLQNITMLENLM
                     TTSVGWLLGIPMGIWFLEQYVATFSTIRLEYTAYVTWQVLLAASVLVWLTSLMTTLFI
                     SRKIRTIDMVDALKGVD"
     gene            3851..5872
                     /locus_tag="TV191_001630"
     CDS             3851..5872
                     /locus_tag="TV191_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1508122.1"
                     /translation="MITKKQRKLKRHTTIRRLCHQALAATLITGSLMGTGLLGNKVVY
                     GDMKSDAKKVLATLQKGNHKQELKKVLRTIGDDSLLLLWLLVSGDSNLDESNKSFDYL
                     SIWNTGSRVGKVISPTEYFKQESKNTENRQAVYSEFKQRVEERSKKAKEATEALNQKA
                     QLEATVKNINEELEKTREGFKVVSENSNKLEKQLMAEKIKTRTAEETAKQAKTDKEKA
                     EAEAKKAKEEAKTAEGKVKQAETEKRNAEAKARTAEEEAKQATADKEKAETEAKKAKE
                     EAKTAKEAAHQEQEKAKQLEQANQQANQRANLAEKSKKDLETQKEKLEQEIKEATEAK
                     NKAEQKLKDLQDSASQGSELSKQLLKEKEELTTKLQELQKQAEEKTTEIEKLKQELEA
                     NKQNSGQLGQQEQKLQEQLNKVQKELKQKEMELKQAQEQLKQEQKPHEGGGDSDASKA
                     RITELEKQVQTLTKEKADLSSTLESTKAQLSETQARLSEAQKQLTAAQEKLTTLEAEK
                     TALQHQVETISKQLSETRDLSEKEKAALQEQINKLKAEIEQKTKEIEALKQGMQSHQG
                     QEKPKDPKTPETPKDPKTPEKNDQPQAPEKRSVPWTALTPAKPIDTTKAPKSSAPSPQ
                     TGAATPKKQLPATGDTATPSFFTAAAMAVLASVGVLNLSPRRKKNQNNR"
     gene            6289..7131
                     /locus_tag="TV191_001631"
     CDS             6289..7131
                     /locus_tag="TV191_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEL1508123.1"
                     /translation="MVSVLSRVIKGIIIALGFILPGVSGGVLAAILGIYERIIAFLAH
                     IREHFVENVLFFLPVGVGGILGIALFSYPVDYLLKHYQVPVLWGFAGAIIGTVPSLIK
                     TSTKTSQRDQVDWLWLVLTFVLSGLGLYFLNDLVGTIPASFTAFVLAGALIALGILVP
                     GLSPSNLLLILGLYSPMLIGFKSLDLVGTFLPIAIGGLLTMLAFSKIMDFALKHYHSR
                     VYHFIIGIVLSSTLLILIPNSSNKEAISYAGAGLGTWLMALLLFGLGVWLGLWMSQLE
                     EKYK"
     gene            complement(7234..>7718)
                     /locus_tag="TV191_001632"
     CDS             complement(7234..>7718)
                     /locus_tag="TV191_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HEL1508124.1"
                     /translation="FKPGEVSFPSGRVEEGETYQQAAIRETVEELNIEPEQVHVWGEI
                     DYLVQPTRSIHCFVAELAIDDWRRLRVNEEVDSLFTVPLEELMAQAPVAYPLQMQSII
                     SSDFPLDRIPNGEQYRLRYMQDQVLLYEHLEKPIWGITAQLTNRFIEIVTEARQHDDI
                     "
BASE COUNT         2553 a         1595 c         1541 g         2029 t
ORIGIN      
        1 tggaagaggc ttttataaaa aatacatgaa tgcctatggg caggtggcaa ggctgcattc
       61 tcagcaatgg tacaccgatg tcgttcatct tcctgttgaa tttcctatgt cagccgatgg
      121 gcataggcca gtctctgaga ggtaccggac actatcagac aaagaaatca gagaaggctt
      181 tctctccatt ggaaaaacac cggagcttgt cagtggcagt caggtcgaga gattgcgaaa
      241 aatcattaac ctatatgacc tgccggttgt cgttccaatt gacgaggcag tcactcaagc
      301 agaggagcaa atcagaacca acagagaagc tgtctccaag cggattattg agcagtataa
      361 agagccttca ttaaaagaaa aaataaaatt tatatcagaa ttttaggagt gtagatgatt
      421 tcatttaaga atattagcaa gacataccaa gtcggagacc aagaggttaa agtattagac
      481 gatgtttcct ttacgattga aaagggaagg tttactgtta ttttaggccc ctctggttca
      541 ggaaagagca cgctcttaaa tttacttgga ggaatggacc gggcaagcaa gggaaccttt
      601 atctttgagg gtaaggacat tacagcctta aatgataaag cattatctga ttatcgcaaa
      661 gaggttgtag gctttgtctt tcagttttac aatcttattc caagcctaac agccttagaa
      721 aatatcagta tcgccgcaca gctaaccgga aacacagcac aatcagaggt attgttggat
      781 aaggtggggt tatctcatcg gaaaaacaat ttccctagcc agctgtcagg cggagaaatg
      841 cagcgcgtat ccatagccag agctctggca aagaagccaa aattattgct atgtgatgag
      901 cctaccggtg cccttgattc caaaacaggg cagcacatta tgcagctact tcaggaagcg
      961 tcaaaggacg aggacgtagc ggttgtcttg gtgacacata acactgaatt taaagctttt
     1021 ggcgatacca ttatttacct aaaggacgga aagataagct cgattgatca taaacaatca
     1081 gtttagagga ttggagctaa acatgaaata tcttaattta aagctaaggc gagatttaaa
     1141 gcatcattgg cagcaattct tttcagtgtt cttgatgtcc ttattaagtg ttttaatctt
     1201 tgttggtcta cagggtgctt ggcatgggct ggaaaaaagc ttagacaact atatatctac
     1261 ctctcatttg ccaaccgttt gggtacaggc tactaatcta acaaaacagg acattgaaaa
     1321 aatagaggcc ttaaatcaag tcagcaaggt tagacctaag attagggtca ctgctgctat
     1381 tgattctgac agcgacctag agcattactt aacgctagat tcattacagt ctacctcaga
     1441 tcaggtgaca cgtgttgtag ctggcgaggc cttttcaacc aaagaaaccg ataaagtatg
     1501 gttgaacaag gaatatgctg acgctaacca cctatccctc ggtgataaga tcagcttaac
     1561 actatcaggt caatcaatta gtgtgactct tgcgggtctt gtccagtcag cagacaggat
     1621 ctactttaca ggcagcttag agtatatagc tcctaattat gataactatg cctacggcta
     1681 catctcaaaa aagagcttag ctaagctcct tcagacgcag ctgcctgata atatggttga
     1741 catttacgcc tcgtctgacg atcttcgaga cgacatagag aacattttag gcaataagct
     1801 tgtttcttat tacaatcaaa caaccctaac tgacgtctct gaggcagttg atagagtagg
     1861 acagattagg aatctctctt atttgttctc ctttatcttc atcttactag ctattctatc
     1921 catgtttacc acgatcagac gtctcatcga aagtcaaaca aaggaaattg ctatcatcaa
     1981 ggccttaggc tattctaaca tacaggtcag tggccactac atttcctttg gcttgttggt
     2041 tggaacatta ggtgctcttt ctggtcttct ggtatctcct gctatgtcct ggtttgtcct
     2101 agagacccaa aagagaatgt tctcacttcc taagtgggaa attgcttact ctctgtcttc
     2161 cctagtagtt gcattactgg tggttatgat ttgtgtgaca tctgcttact ttgcttctcg
     2221 aaaagccatt aaagggctgc cagcagtatt cttacgagga aaaaacaggg acgtcaagca
     2281 tattttgctc gaaaaaatca agcccttatg gcgtagtatt tctgacgaag ctaagtgggc
     2341 tatacgtgat gctttgacac accgcatcag aattttaatg gggattatag gggtagctgg
     2401 tagtatgatg cttttaattg ccggtattgg catgcctatc tctatgaatc accttgttga
     2461 taaggcctat aacaaggact ttagctactc caaacgcttg acggtttctg actacgaatc
     2521 ggccaataag gcctataaag gccaatgggt gcaaatcaat caagcccact tctcaaaaga
     2581 tgacggctac aatcgtctct tgattattat cagcaaggga agccttgtta acgccaccac
     2641 agaagatggt gacaagataa aagagggtgg tctctatgtt accaacagct ttgccaagct
     2701 agccaatatc aaggttggag acaagctatc tgtcacaccc taccaggata agcatcagta
     2761 tacctttagt gttaagggaa ttctgaccag cgaaactaat caaggtgcct atatcatggc
     2821 tgataccttc aaaaaagcag gcggagcttt tcacccacac acattgttag tagataagca
     2881 agtttctgct tctacaatcg ctcaggatca gaatgtttta accgtcattg ataagtccag
     2941 ccaagaaagc aatgcctatg accttgtcaa tagtctaatg agtgtctttt tgatgatcat
     3001 tggctttgcc ttgctgctag tcatcgttgt gctgtataat ttaggctctt taaattttgt
     3061 agagcgcaca agagactacg caacccttca ggttctagga ttttcaaaaa gaaatctcca
     3121 aaacataaca atgctcgaaa atctcatgac aacctctgtg ggctggctct tgggaattcc
     3181 tatggggatt tggtttttag agcagtatgt cgccaccttc tctacgatac gtcttgaata
     3241 tacggcttat gtcacttggc aggttctgct agcggcaagt gtccttgtct ggctaacatc
     3301 attaatgacc actcttttca tcagtagaaa gattagaaca attgacatgg ttgatgcctt
     3361 aaagggagtc gactaacctc actttatcac atacctgact ctctctcttt tatggttaag
     3421 catcatcact gcactggttc tgatatgatg actgataaag ctgtaattgt gctgtaacaa
     3481 gcactgtcat tacatagcaa cacccttaaa aacaagcatc agatttggtg cttgtttttg
     3541 aatttattgc taatgctaaa cgcaacgatt atcacaaatc atgcagtaca cgcttataac
     3601 agcttaagca tgcccattat tcaaaaaacg ttgatcaaaa tgacttccct gaagtttaga
     3661 tcattcctca atttattgat acaaatgtga taaagtcata cgatcttctt gtttattaaa
     3721 aaaaaaaaaa aacgaaacta cggagagaaa gatgagcttt gtcgtttctc acttccaacc
     3781 gccatgttaa aatcttctct gagaaagaat gttataaaaa ataatcattc tatcaccaaa
     3841 ggagagaaaa atgataacta aaaaacagag aaaactaaaa agacacacaa caatcagacg
     3901 cctgtgtcat caagccctag cagctaccct catcacagga agcctgatgg gaacaggact
     3961 acttggaaat aaagtcgtgt atggggatat gaaaagcgat gccaaaaagg tattagcaac
     4021 attgcaaaaa ggtaatcata aacaagagtt aaaaaaagtt cttagaacta ttggtgatga
     4081 tagtttgcta ttattatggt tacttgtatc gggtgattcc aatttagatg aaagtaataa
     4141 aagttttgat tatttatcaa tttggaatac tggatctaga gttggtaaag tgatatctcc
     4201 tactgaatac tttaaacaag aatcaaaaaa cactgaaaat aggcaagctg tttatagtga
     4261 atttaaacaa cgcgtagaag aacgatctaa aaaagccaag gaagccactg aagcactaaa
     4321 ccaaaaagct caattggagg ctacagttaa aaatataaac gaagaacttg aaaaaactag
     4381 agaaggtttt aaagttgtga gtgaaaactc aaacaaatta gaaaaacaat taatggctga
     4441 gaaaataaaa acacgtacag ctgaagaaac tgccaaacaa gctaaaaccg ataaagaaaa
     4501 agcagaggct gaagctaaaa aagcgaaaga ggaagctaag actgcggaag gaaaagttaa
     4561 acaagcagaa actgagaaaa ggaatgcgga agctaaggct agaaccgctg aagaagaagc
     4621 taaacaagct acggctgata aagaaaaggc agagactgaa gctaaaaaag cgaaagaaga
     4681 agctaagacc gctaaagaag ctgctcatca agaacaagaa aaagctaaac aattagaaca
     4741 agctaatcaa caggctaacc aaagagctaa tctggcagaa aaatctaaaa aagatttaga
     4801 aactcaaaaa gaaaaacttg aacaagagat taaagaagct acagaagcta aaaacaaagc
     4861 cgagcaaaaa ttaaaagacc tacaagattc agctagtcaa ggcagtgaat tgtctaaaca
     4921 gctgttaaaa gaaaaagaag aattaacaac aaaacttcaa gagcttcaaa aacaagctga
     4981 ggaaaaaaca actgaaattg aaaagctaaa acaagagctt gaagctaata aacaaaacag
     5041 tggtcagcta ggtcaacagg aacaaaagct tcaagagcaa ttgaataagg ttcaaaaaga
     5101 gctgaaacaa aaggaaatgg agttaaaaca agctcaagaa cagctgaaac aagaacaaaa
     5161 acctcacgaa ggtggcggag attctgacgc ttccaaagca agaatcactg agctagaaaa
     5221 acaagttcaa acactaacca aggaaaaggc agatctgtca tcaacccttg agtcaacaaa
     5281 agctcaattg tcagagactc aagcaagact atcagaagct caaaaacaat tgactgctgc
     5341 tcaagaaaag ttaacaacac ttgaagccga gaaaacagcg cttcaacatc aagttgagac
     5401 catttcaaaa cagctatcag aaacacgtga ccttagcgaa aaggaaaaag cagcactcca
     5461 agagcaaatc aataagctaa aggctgagat tgagcaaaag accaaggaaa ttgaagcctt
     5521 aaagcaaggc atgcaatcac atcaaggtca agaaaaacca aaggatccaa aaactccgga
     5581 aacaccaaag gatccaaaga ctcctgagaa aaacgatcag ccacaagcgc ctgaaaaacg
     5641 tagtgtccct tggactgctc ttacaccagc taagccaatt gacactacca aagctcctaa
     5701 gagctcagca ccaagcccac agactggggc agcaacacct aaaaaacaat taccagcaac
     5761 tggtgataca gcgacaccta gcttctttac cgctgctgct atggcagtat tggctagcgt
     5821 cggtgtccta aatctctcac ctagacgcaa aaagaatcaa aacaaccgtt aatgtagaga
     5881 ctctcatatc tggattgaat aacagcaaac ccgacatgag caaaaacaaa tgtctaacca
     5941 aaaatcactg acattagtac tttaaccaaa gcctttgagt caagctaaac aggctgtcct
     6001 gcctattggc ttgactcgtt ttgtgattgt gaaacacacc aaggtcaaac ctaccttgtc
     6061 ctccatttta aacctactct tttctcccat acccacttta gcttacgcaa gaaggtgcct
     6121 aatcatcact tttggtagct tcgatgctct atataaatgg atcaacaaag ataaatcata
     6181 caaaactgcg agttgttcct atagtcacga tagctcttac agatatgaaa agtaaataca
     6241 gctattaaaa atatggtaca ataggggtac gatttttagg aggcatgtat ggtttcagtt
     6301 ctttcacgag tgattaaggg aataattatt gcgcttggct ttattttacc gggagtatct
     6361 ggaggagtat tagccgctat ccttgggatc tatgagcgta tcattgcctt tttagctcat
     6421 atacgtgagc attttgttga gaatgttctc tttttcctgc ctgttggggt tggtggtatt
     6481 ttagggattg ccctcttttc ttaccctgtt gactatctgc tcaagcacta tcaggtacca
     6541 gtcttatggg gcttcgctgg ggccatcata ggaaccgtac ctagcctgat aaagacttcg
     6601 acaaaaacat ctcagcgtga ccaagttgat tggctctggc tagtattaac ctttgtccta
     6661 tcaggactgg gactttattt cttaaatgat ctcgttggga caatacctgc aagctttacc
     6721 gcctttgtcc tagctggtgc cttgattgct ttaggtattt tggtacctgg tcttagcccg
     6781 tctaatcttt tattaatttt aggactttac tcacccatgc tgattggctt taaatcactt
     6841 gatttggtag gaaccttttt acccattgct attggtggct tattaaccat gctagctttt
     6901 tccaagatta tggattttgc tctcaagcac taccattcac gcgtttacca ctttattatc
     6961 ggtatcgtcc tatccagcac cctgcttatt ttaattccaa atagcagtaa taaggaagct
     7021 atctcttacg ccggtgcagg tcttggcacc tggctaatgg ctctgctatt atttggcctt
     7081 ggtgtctggc ttggtctatg gatgagccag cttgaggaga aatacaaata acactcgata
     7141 caccagcaag tacctctaac agcagcatta agatcaaaaa aacgaatgac tagctctcag
     7201 ccttatcacc agctgtgact agcattcgtt tttttatatg tcatcatgct gtcttgcctc
     7261 tgtcacgatt tctataaaac ggttcgtcaa ttgagcagtt ataccccaga taggcttttc
     7321 taaatgctca tagagtaata cctgatcttg catgtacctc aacctgtact gctctccatt
     7381 agggatacga tccaacggaa agtctgacga gattatcgat tgcatttgta aaggataagc
     7441 aacaggagct tgcgccatga gctcctccaa aggcaccgta aacaagctat caacctcttc
     7501 attgacccta agccttctcc aatcatcaat agccagttcc gcaacaaagc aatgaatgct
     7561 acgagtcggc tgaactaaat agtcaatctc cccccaaaca tgaacctgct caggctctat
     7621 attgagctcc tctaccgtct cacgaatagc cgcctgctga taagtctcac cctcctccac
     7681 gcgcccacta ggaaaagaaa cctcccctgg cttgaatg
//
LOCUS       DARYXW010000090         7566 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.090, whole genome shotgun sequence.
ACCESSION   DARYXW010000090 DARYXW010000000
VERSION     DARYXW010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7566
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.090"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            88..1146
                     /locus_tag="TV191_001633"
     CDS             88..1146
                     /locus_tag="TV191_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HEL1508125.1"
                     /translation="MTTTNKETFSSFMNKVLAGTAIAIVVALIPNAILATFLKPLLPN
                     TVAAEFLHIVQVFQFFTPVMAGFLIGQQFKFNPMQQLAVGGAAYIGSGAWAYTEVIQK
                     GVATGTFQLKGIGDLINMMITAALAVLAVKWFGDKFGSLTIILLPIIIGTGVGYIGWK
                     LLPYVSYVTTLIGQGINSFTTLQPILMSILIAIAFALLIVSPISTVAIGLAIGLNGMA
                     AGAASMGIASTTAVLVWATLKVNKSGVPIAIALGAMKMMMPNFLKYPVMAIPMMMTAI
                     VSSLTVPMFNLIGTPASSGFGLVGAVGPIASLAGGSNIVIIIIAWLVIPFGVAFVAHK
                     LCKDILKLYKEDIFVFEG"
     gene            1158..2081
                     /locus_tag="TV191_001634"
     CDS             1158..2081
                     /locus_tag="TV191_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000964166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HEL1508126.1"
                     /translation="MLVYIAGSGAMGCRFGYQISKTNNDVILLDNWEAHLQAIKENGL
                     KISGDVEETVKLPIMKPTEATKEADLIILFTKAMQLPQMLTDIKGIIGPETKVLCLLN
                     GLGHEDVIRHYIPEHNILMGVTVWTAGLEGPGQVHLQGVGALNLQSMDPANQEAGHQI
                     ADLLNDAQLNATYDDNVVPNIWRKACVNGTMNSTCALLDCTIGELFASEDGLNMVKEI
                     IHEFVIVGRAEGVELNEEEITAYVMETSVKAAHHYPSMHQDLVQNHRLTEIDFINGAV
                     NTKGEKLGIDTPYCRLITQLVHAKENILKIK"
     gene            2516..3229
                     /locus_tag="TV191_001635"
     CDS             2516..3229
                     /locus_tag="TV191_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEL1508127.1"
                     /translation="MAKITAENYVALEDLMQLLSSSESTVRRDLDELEREGKLHRVHG
                     GAELFHSLQEELSNQEKSVKNSQIKEIIAQKAAELVFDNDVIFIDAGTTTEFLLPFLQ
                     LKKVTVVTNSIHHATRLVDMAIKTIIIGGYVKQTTDASIGHVALEQIRQMNFDKAFLG
                     INGIDEAFLTTPDMEEAVIKKAVIANAKITYVLADATKLGHVSFVKVAPIDRVEIITE
                     KSSTVMLKKIKEKAKVIAL"
     gene            3226..4137
                     /gene="pfkB"
                     /locus_tag="TV191_001636"
     CDS             3226..4137
                     /gene="pfkB"
                     /locus_tag="TV191_001636"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEL1508128.1"
                     /translation="MIYTVTLNPSIDFIVRIDQLDIGAVNRMVSDDTFAGGKGINVSR
                     ILQRLGIDNTATGFLGGFTGRFIKESLAAESINTDFVTVDQDTRINVKIKSAEETEIN
                     GLGPVISKQQLDHLKAILANVSAEDIVVFAGSAPSSLGNDVYKDLIPLVRQAGAQVVC
                     DFEGQTLLDALAYHPLLVKPNNHELEAIFNVSLNGLDDVETYARKVLDMGAQHVIVSM
                     AGDGALLVTQEATYFAKPIKGQVKNSVGAGDSMVAGFTGAFVKSHSPLEALKWGVACG
                     TATAFSDDLAAIDDIKKTYNEVEVEVR"
     gene            4134..6080
                     /locus_tag="TV191_001637"
     CDS             4134..6080
                     /locus_tag="TV191_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEL1508129.1"
                     /translation="MKIQDLLRKDIMILDLQAVSKEAAIDEMITELVEHGIVHDFDVF
                     KKSILAREEQTSTGLGDGIAMPHSKNVVVDQPAVLFAKSNKGVDYKSLDGQPTDLFFM
                     IAAPQGANDTHLAALAELSQYLLKDGFADQLRKATSPDEVIAVFDAASDQKEVAFVPT
                     NAQEFIVAVTACTTGIAHTYMAEEALKKQAAQMGVGIKVETNGASGVGNRLTADDIKQ
                     AKGVIIAADKAVEMDRFDGKQLIARPVADGIKKSEELISLILNNAGSVYHAKNGAAEQ
                     AKAAQKTSLGGAFYKHLMSGVSQMLPFVIGGGILIALAFLLDNMLGVPKDQLSNLGSY
                     HEIAAIFKHIGGAAFSFMLPVLAGYIAYSIAEKPGLVAGFVAGAIASSGLAFGKVPFA
                     AGGEASLSLAGVPSGFLGALVGGFLAGGVILALRQVLAGLPRSLEGVKSILLYPLLGV
                     LVTGLLMLLINIPMAAINTALNHFLESLSGSSAVLMGLLVGGMMAVDMGGPVNKAAYV
                     FGTGTLAATVASGGSVVMAAVMAGGMVPPLAVFVATLLFKDKFTKEERESGLTNIIMG
                     LSFITEGAIPFGAADPARAIPSFIAGSALTGALVGLAGVKLIAPHGGIFVIALTSNPF
                     LYLLFVAIGAVVSGILFGALRKKA"
     gene            6658..7257
                     /locus_tag="TV191_001638"
     CDS             6658..7257
                     /locus_tag="TV191_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEL1508130.1"
                     /translation="MKRRKARRSHREASSWLAAGIVLGSMLLSLWTLASAKDHLKPHA
                     NSSTMLFVSKISHSAQAVAQRNKLYASVMMAQAILESANGQSKLSQEPYYNFFGIKGS
                     YKGKSVILPTLEDDGQGNLYLIDASFRSYGSLTACFEDYARVLSDPLYRPTHRGIHTS
                     YQQATASLTGTYATDTSYGEKLNRIIGDYQLTYFDAPIR"
BASE COUNT         2118 a         1382 c         1772 g         2294 t
ORIGIN      
        1 attaaaatag ctgtgacaaa atgctctttt tatgttagaa tactttcgtg atgtttttca
       61 cactataata ttaagagagg tcatgaaatg acaacaacaa ataaagagac ctttagctcg
      121 tttatgaata aggtcttagc tggtacagca attgcgattg tagttgcact tattccgaat
      181 gctattttag cgacgttttt aaagccgctt ttgccaaata ctgtagcagc tgaattttta
      241 catatcgtcc aggttttcca attctttacg ccagttatgg ctggtttttt gattggacag
      301 cagttcaaat ttaacccaat gcagcagctg gctgtcggcg gggcagctta tatcggttct
      361 ggagcttggg cttatacaga ggttatccaa aaaggtgttg ccactgggac cttccagcta
      421 aagggcattg gtgatctgat taatatgatg atcacagctg cgcttgccgt tttagcagtg
      481 aagtggtttg gtgataaatt tgggtctcta accattattt tgttgccaat tattattgga
      541 acaggtgtgg gttacattgg ctggaagctg cttccttacg tttcttatgt gacgaccctg
      601 attggccaag gcattaattc atttacaacg cttcagccaa ttctgatgtc tattttgatt
      661 gccattgcct ttgctctttt gattgtgagt ccgatctcaa cggttgcgat tggtttagct
      721 atcggcttaa atggtatggc agctggtgcg gcctcaatgg gtattgcttc aacaaccgct
      781 gttcttgtgt gggcaacgtt aaaggttaac aaatcaggtg ttccaattgc cattgccctt
      841 ggcgctatga aaatgatgat gccaaacttc ttaaaatacc cagttatggc tattccaatg
      901 atgatgacag ctattgttag ctctttaacc gttccaatgt ttaatctgat tggaacacca
      961 gcctcatctg gctttggtct tgttggtgca gttggtccta ttgcttcact tgccggtggc
     1021 agcaatattg tgatcattat cattgcttgg ttggtcattc catttggagt tgcttttgtg
     1081 gcacataagc tttgtaagga tattttaaag ctttataaag aagatatttt tgtatttgaa
     1141 ggataagagg aaaaagcatg ttagtttata ttgcaggctc aggagctatg ggctgtcgat
     1201 ttggttacca aatttcaaaa acaaacaatg acgttatttt actggataat tgggaagcac
     1261 atcttcaagc gatcaaagag aatggcttga agatttcagg cgatgtagag gaaaccgtaa
     1321 agcttcctat catgaagccg acagaggcta ctaaggaagc tgaccttatc attttgttta
     1381 ccaaagccat gcagctgcca caaatgctga ctgatattaa aggtattatt ggccctgaaa
     1441 ccaaggtact ttgcctatta aatggtcttg gacacgaaga tgtgattcgt cactatattc
     1501 cagagcataa tattttaatg ggtgttaccg tttggacagc gggtcttgag ggacctggtc
     1561 aggtacactt acaaggagtt ggtgcgctta atctacaaag catggatcca gcaaaccaag
     1621 aggcaggaca tcagattgct gacttgctaa atgacgctca attgaatgca acttatgatg
     1681 ataatgttgt tccaaatatt tggagaaaag cctgtgtcaa tggtacaatg aactcaacct
     1741 gtgccctact tgattgcacg attggtgagt tatttgccag cgaagatggt ttaaacatgg
     1801 ttaaagaaat cattcatgag tttgttattg ttggtcgtgc tgagggggtg gagcttaatg
     1861 aagaggaaat cacagcctat gtgatggaaa cctcagtgaa ggctgctcat cactacccat
     1921 caatgcatca ggatcttgtt caaaatcacc gcttgactga aattgacttt atcaacggtg
     1981 cggtaaatac caagggtgaa aagcttggta tcgatacccc ttattgccgc ttgattacac
     2041 agctagtcca tgccaaagag aatattttga agatcaaata ggtttagaca taaggagtct
     2101 gggataaaac aatttctcag tacaataaaa cgagaggctc acaataggtg actctctcgt
     2161 tttgtcttgt tggctgaaaa gactttgtcc tagactctca ttatgaagca acgacagtaa
     2221 atccgttgct ttttgatttg taagagacta ttgtgtttca gacttttgca acaggtgagc
     2281 gctttttggg ctctagttaa taaaaaagtc gttaatcatt agtctacagg tattgacggg
     2341 gacaatgact gatcaattgg cagttattgt taaggcaata gaggtctaag attgaatttg
     2401 aatgttttta aaagatagtg cttgactttg gaataaagtg tagtataata gagctgtaaa
     2461 cgatttcaga caaaggggtg gttttatctt aaaatcaaaa cgaaaacagc tcattatggc
     2521 aaaaatcaca gctgagaatt acgttgcgct agaggattta atgcagctgt taagctcgtc
     2581 agaatcaact gttcgtagag atttagatga gctggagcgt gagggcaagc ttcatcgagt
     2641 gcatggaggt gccgagcttt ttcattcctt acaagaggaa ttatctaatc aggaaaaatc
     2701 tgtcaaaaac agtcaaataa aagaaatcat cgctcaaaag gcagcagagc tggtttttga
     2761 taatgatgtc atctttattg atgctgggac aacaaccgaa tttctccttc cttttttgca
     2821 attaaaaaaa gtaacagtag tgactaattc tattcatcat gcgactagac tggttgatat
     2881 ggcgatcaag accattatta ttggtggcta tgtcaagcag acaacagacg caagcatcgg
     2941 tcatgttgcc ttggagcaaa ttaggcaaat gaattttgat aaggcttttc ttggtatcaa
     3001 tggtatcgat gaggcatttt taaccactcc ggatatggag gaggctgtta ttaaaaaagc
     3061 tgtcattgcc aatgctaaaa tcacctatgt attagctgat gcaacaaagc ttggtcatgt
     3121 ttcctttgtc aaggttgctc caattgatag ggttgaaatc attacagaga aatcttcgac
     3181 agtaatgctg aagaaaatca aggaaaaagc gaaggtaatt gcactatgat ttacacagta
     3241 accttaaatc cttctataga ctttattgtc agaatagacc aattagatat tggagcggtt
     3301 aaccgcatgg tcagtgacga tacatttgca ggaggaaagg ggattaatgt tagtcgcatt
     3361 ctacagcgat taggcattga taatacagcg actggctttt taggcggctt cactgggcgt
     3421 tttattaagg aaagtctagc tgctgagagc atcaatactg actttgtaac ggttgatcag
     3481 gatacgcgga tcaatgttaa gatcaaatca gcagaggaga cagagattaa tggccttgga
     3541 ccagtgattt caaagcagca attggatcat ttaaaggcta tattggcaaa tgtgtcagca
     3601 gaggacattg ttgtttttgc aggctcagcg ccttcaagtc taggcaatga tgtctataag
     3661 gacttgatcc cattggtcag acaagctggg gcacaggtgg tctgtgattt tgaaggacag
     3721 accttgctag atgcattggc gtatcaccca ttgctcgtaa agcctaataa ccatgagcta
     3781 gaagctattt ttaacgtcag cttaaatggg ctagatgacg ttgaaacata tgctcgtaag
     3841 gtccttgaca tgggagcgca gcatgttatc gtttcgatgg ctggtgatgg tgccttgctg
     3901 gtcactcagg aagcaactta ttttgctaag cctattaaag ggcaggtgaa gaattctgtt
     3961 ggagctggtg attcgatggt ggcaggcttt acaggtgcct ttgtcaaaag tcatagtccg
     4021 ctagaggctc taaaatgggg agtggcctgc ggaacagcaa ctgctttttc agatgattta
     4081 gcagcaattg atgatattaa aaaaacatat aatgaggttg aggtagaggt tcgatgaaaa
     4141 tacaggattt attaagaaaa gacatcatga ttcttgattt gcaggctgtt tcaaaagagg
     4201 ctgcaattga tgaaatgatt acagaactag tagagcatgg gattgtacat gactttgatg
     4261 tgtttaaaaa gagtatctta gctcgcgagg agcaaacctc aacaggtctt ggcgatggca
     4321 ttgctatgcc gcattcaaaa aatgttgttg ttgaccagcc agcagtgctc tttgcaaaat
     4381 ctaacaaggg cgttgattac aaatccttag acggtcagcc aactgatctg ttctttatga
     4441 ttgcagcacc tcaaggggca aatgatactc acttagcggc cttagccgaa ttatcccaat
     4501 acctattaaa ggatggcttt gcagatcaac tgcgaaaggc aacaagtcca gacgaagtga
     4561 ttgctgtctt tgatgcggct tctgatcaga aagaggtagc ttttgttcct acaaatgctc
     4621 aggagtttat cgttgctgtg acagcttgta cgacaggtat tgcacatact tatatggcag
     4681 aagaggcctt gaaaaagcag gctgcacaga tgggtgtcgg catcaaggtt gaaaccaacg
     4741 gtgcttcagg ggttggcaat cgcctgacag ctgatgacat caagcaggcc aagggagtga
     4801 ttatcgctgc tgataaggcg gttgagatgg atcgctttga tggtaagcaa ttgattgctc
     4861 gtcctgtagc agatggtatt aagaaaagcg aggaattgat ttcactgatt ttaaacaatg
     4921 ctggtagtgt ttatcatgcc aagaatggcg ctgctgaaca agcaaaagca gctcaaaaga
     4981 caagcctagg cggagccttc tacaagcacc tgatgagtgg tgtatcacaa atgctgccat
     5041 ttgtaattgg tggtggaatc ctaattgctc ttgccttctt gcttgacaac atgcttgggg
     5101 taccaaagga tcagctgtct aatttgggat cctaccatga aatagcagct atctttaaac
     5161 atattggtgg tgcggccttt tcattcatgt tgccagtgct agcaggctac attgcttatt
     5221 ctatcgctga aaagccaggt cttgtggcag gctttgtggc aggtgccatt gcttctagcg
     5281 gtcttgcttt tggaaaggtt ccatttgctg ctggcggtga ggctagccta tcattagcgg
     5341 gagtaccgtc tggatttctt ggtgcgcttg taggtggctt ccttgcaggg ggagtaattc
     5401 ttgctcttcg tcaagtgctt gcagggcttc cgcgttcgct tgaaggggtc aagtcaatcc
     5461 ttctttaccc attacttggt gttcttgtga caggtctttt gatgctgctg atcaatattc
     5521 ctatggcagc tatcaataca gcattgaacc acttcttaga aagtctgtca ggtagctctg
     5581 cagttcttat gggacttctt gttggcggca tgatggctgt tgatatgggt ggtccagtga
     5641 ataaggcagc ctatgtcttt ggtacaggaa cacttgctgc aaccgttgca agcggtgggt
     5701 cagttgttat ggctgctgtc atggcaggtg gtatggtgcc tcctctagct gtttttgtgg
     5761 caacactctt atttaaagac aaatttacca aggaagagcg tgaatctggc ttgaccaaca
     5821 ttattatggg actttccttc attacagaag gagccattcc gtttggtgca gcagacccag
     5881 cacgcgctat cccaagcttt atcgctggct ctgccctaac aggtgctctt gttggtctag
     5941 caggtgtcaa attaatcgca ccacatggcg gtatcttcgt tatcgctttg acaagcaatc
     6001 ctttcttata cctattgttt gtcgctattg gagcagtggt ttctggtatt ctctttggcg
     6061 cacttcgtaa aaaagcttag ttactggcta taaagccaca agtactaggg aaagcttctg
     6121 aattagacct agtcttaata aaacatcaga cgcatgacat cagcctgttt ttacatgatg
     6181 tcgtgcgttt tgtttgttgc tagtagtgat gactggcgaa aagctaatat ttagagagaa
     6241 tcaatctgat ctagaatagc taagcagtga cccaatagcc ctgctaaact aagccacacc
     6301 aaacgtgcga aacagttatt ttcgaattat agtatcaatt aaagtagata ctatcaacgt
     6361 ttttcctata gtaacatcta tcaaaaataa gatatattct tgaaatagct aaacattgaa
     6421 atcatttgat tgtagatatt ccatttattt tttgtatcgc tccctttgca ggagcgtgga
     6481 ttgaaataca gcaaagtctt cttttcttgt taaaaacttt ttatgcgcct gttgtggctg
     6541 ctaggtcttt ttagaagtca taaggcctgt ttttgaggtg agcatgtggt ctggctacat
     6601 tttgctttta atttttgcta tactaggttt aaaagcaagg aagtgaggat atttctgttg
     6661 aagaggagga aagctagaag aagccacagg gaagctagct cttggctggc tgctggtatt
     6721 gttttaggca gcatgttgct tagcctttgg accttagcgt cagctaagga tcaccttaag
     6781 cctcatgcca atagctcaac catgctattt gtgagcaaga ttagtcattc cgctcaggca
     6841 gttgcgcagc gaaacaagct ctatgcctca gtcatgatgg cacaggctat tttggagtca
     6901 gcaaatggtc aatctaagct aagtcaagag ccctattata atttttttgg tatcaaagga
     6961 agctataaag gaaaatcagt tattttacct accttggaag atgatggcca aggcaacctt
     7021 tatctaattg acgcttcttt tcggtcctat ggcagcttaa cagcctgctt tgaggattat
     7081 gctagggttt tgagtgaccc gctttatcgc cctactcacc gaggtattca tacaagttat
     7141 cagcaggcca ccgctagttt aacaggcaca tatgccacag atactagcta tggcgaaaag
     7201 ctcaatcgta ttatagggga ttatcagctg acttattttg acgctcccat acggtagcta
     7261 cctccagcat gactgatcta acgagattaa cctcatcaga acagcaaaat aattttctaa
     7321 aatagttaga aaagatcaaa cagcccttta cgaacgttta agacgagatg gtgacatgca
     7381 aggagaaagc aattctacaa atgatgtgag aaaatactat gtgtaaggct gggtagatga
     7441 ttaaacggtc tggtttggct tattgatgga ttaaatggat agttaaacta caaatagaca
     7501 aggtgtattt ttacctgtaa gtagtggcta acagtgagat agcagaaatg ctatcttctt
     7561 ttgatt
//
LOCUS       DARYXW010000091         7527 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.091, whole genome shotgun sequence.
ACCESSION   DARYXW010000091 DARYXW010000000
VERSION     DARYXW010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7527
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.091"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(209..424)
                     /locus_tag="TV191_001639"
     CDS             complement(209..424)
                     /locus_tag="TV191_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508131.1"
                     /translation="MVDKYIPGRYIQREIDEIIELVRDRSKFEPVRVREVQEHIQKIL
                     IQHEAEILARLEENQDQKASENSNDIF"
     gene            613..903
                     /locus_tag="TV191_001640"
     CDS             613..903
                     /locus_tag="TV191_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508132.1"
                     /translation="MAIEVFGPDFRKELLADLISLNREALKIAQFENSKSIEWVTMKR
                     LEKETGWGRTKLTQWREQGKFNFKRSSENGKVLYDLADVNRFLRTSGYEKGA"
     gene            905..1099
                     /locus_tag="TV191_001641"
     CDS             905..1099
                     /locus_tag="TV191_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508133.1"
                     /translation="MNKLELFLLAATVILAIIARIQYEVIKKHNSPENKRKIFREVAL
                     ENSKRWSEKRSRGEVEKCLL"
     gene            1234..1413
                     /locus_tag="TV191_001642"
     CDS             1234..1413
                     /locus_tag="TV191_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508134.1"
                     /translation="MTTTKKLGRPTSNPKSHSKRLRMTDEEVQKLEYCTKQTGKTQTD
                     VLMLGLDKVYQELKK"
     gene            1586..1858
                     /locus_tag="TV191_001643"
     CDS             1586..1858
                     /locus_tag="TV191_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508135.1"
                     /translation="MDNSKLANHQKVTVVCTDFNVYLNGIRLTGARPETAKLAERCGE
                     KLITLSLVVTDFDDHRTPKMADMAKEAEMANKTLDWEKKHFYKSNK"
     gene            complement(1848..2228)
                     /locus_tag="TV191_001644"
     CDS             complement(1848..2228)
                     /locus_tag="TV191_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508136.1"
                     /translation="MIDYYSLYKNSLEAIGYHKLDTGVDLLQYLIATEEGKRIYSQYP
                     YREVEEIIFYTLDCLIQQDLVTATEMPRLDRRIYTIDGLTPKGMYFLGYIGQVETEVI
                     EWLNEFGVSQNPESIYNALRYIIY"
     gene            2284..2727
                     /locus_tag="TV191_001645"
     CDS             2284..2727
                     /locus_tag="TV191_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508137.1"
                     /translation="MAKTYTLTEEELNELVAERMKQAKEKRTPQGLFKDVSFDDELIP
                     INEKYPKVLKKLNRERAYKPEKHVFNQTPKVFGVDNDISYSKITTHDVHNHIRLLVLN
                     VFGKSQNKEVLPEEYDQAIELYKELKEWFVSSYDKRLEGLVLEDD"
     gene            2844..3656
                     /locus_tag="TV191_001646"
     CDS             2844..3656
                     /locus_tag="TV191_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017285243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEL1508138.1"
                     /translation="MGKEKTKIYFWLKFDKKFFENIFIKRLKKMAGGDTMTVLYIRLM
                     LESLETDCILYYEGYFENLVEELAIKLEVSEDDINMTLAYFTKCGLIQIDGSGNAQMP
                     QAKAMLESETNWAKYKRETRKIGQIPTNVQPMSNQCPTEIEIEKDKKKDINIDIKSEV
                     EEEIKEISTADENSLKIISDYFQQEIGILSPNQFEQLSDYITITKMEVDVVKSAITRA
                     ADNSKRSFGYVNSILRNWRQNGITTMVKVKEESRNFKARKAKQEEVSEYDTW"
     gene            3643..4425
                     /locus_tag="TV191_001647"
     CDS             3643..4425
                     /locus_tag="TV191_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEL1508139.1"
                     /translation="MTLGDNNALAKIAVAYQKNVKKESTVCQKHGCIYITILKTGLTV
                     CPMCHKEDLESQNELHVQKQYERELENKRLYYLKKLSIMDDELENASFDNFRVITPKQ
                     QEVLSWAKSMANYWYTGGKGNIIMTGKAGRGKSHLAYSIIRGLSDETKKLGLLVNITD
                     LLSEIKRDFSQEAFWLDKLKNVDYLVLDDLGAEKVSDWSTSIIYSLLNKRTNTIITTN
                     LTPVEIRKNYGERIASRIRKGCAKSHIMDFAGLEDERIKLWN"
     gene            4562..4768
                     /locus_tag="TV191_001648"
     CDS             4562..4768
                     /locus_tag="TV191_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508140.1"
                     /translation="MTPEEAEKAKIRAKQEIEVFSIYLEQAIDTFGSMLSPQEVFLAA
                     GFAYLGAGQTDIHAAVEGLYEQVR"
     gene            4930..5856
                     /locus_tag="TV191_001649"
     CDS             4930..5856
                     /locus_tag="TV191_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HEL1508141.1"
                     /translation="MANQLSTYTHKQFFNAPTIQKAFDDVWKGAGTQFAVSILSVLQG
                     SKSLKSASNESIYAAAMKAAVLNLPIEPSLGRAYLVPYKGQAQFQLGYKGLIELAQRS
                     GQYKNINAGIVYKSQLISYNPLFEELILDFSKPQDEIVGYFAAFKLLNGFEKVSFWTV
                     EKVTAHGKKFSKSFASGPWKTDFDAMAQKTILKDILSKYGPLSVEMQKAIDEDNQDST
                     ISIPKDITPPETNSLDDLIGHQNEKKDAPGNLKDVTDDLHSEPEKTLTDENKTVLEDT
                     SYPADEIPDFDQETGEIKASEGNLFDNLGDLI"
     gene            5853..6053
                     /locus_tag="TV191_001650"
     CDS             5853..6053
                     /locus_tag="TV191_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508142.1"
                     /translation="MIKLVKIEGYYINPEYVVGVWERSALNFDDLDEKVVVIQFVGDR
                     EREECVFYDTPIDEVIKRLLDD"
     gene            6046..6843
                     /locus_tag="TV191_001651"
     CDS             6046..6843
                     /locus_tag="TV191_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease-like domain-containing
                     protein"
                     /protein_id="HEL1508143.1"
                     /translation="MTSLDLLGKDYYSKESAIRYWSISQYKRFRECEARALAELRGDW
                     TDTRDNTALLVGNYVHSYFEGEEAHEEFKVQNSSEMISTRGTTKGQLKKDYLVAEQMI
                     DALKSDNNFMAIYQGEKEVAITGFLGEVEFKGKIDCLNAERGYFVDIKTTKGPIDDKI
                     WNGQERVYWFEAYSYILQMAAYKNMLEAKHKKPFEPIIYAVTKETPPDTRAIRIQNLD
                     AMQNELDNLAQNIKRLDDVKKGIEKSKPCGHCEYCRANQLTQRVMIF"
     gene            7022..7363
                     /locus_tag="TV191_001652"
     CDS             7022..7363
                     /locus_tag="TV191_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508144.1"
                     /translation="MEQIKITGTGTALILDRVNRIFAISGGLTMQWDFISDFKKIDDE
                     PSLDEDGELFEVAYDLVLEAKPKTKINLTSSYFAKEHKKDTDEIIKVFSFIEDNKRNI
                     FETLGIRGVLE"
BASE COUNT         2773 a         1244 c         1521 g         1989 t
ORIGIN      
        1 gggcagcagt attttatcaa caaatttctt aaccaggaat atctgccagt ttagaaagga
       61 aaccacatga gaccaaaacg atatccgtat acaccaaaaa gaccctttcc gagtcaagaa
      121 agagtcgcaa gttatagatt ggctattgaa gagttaaatt ctttagcacc aacagcatcc
      181 gaaacactaa agaaaaaaat agaagaagct aaaaaatatc atttgagttt tctgaagcct
      241 tttgatcttg attttcttct aaacgagcaa gaatctcagc ttcatgttga ataagaattt
      301 tttgaatatg ttcctggact tcacgaactc taactggttc gaacttactt ctatcacgaa
      361 ccaattcaat aatttcgtcg atttctcttt gaatataacg accaggaata tatttatcaa
      421 ccatgtaatt tatcctcctt tatagcatat ttgactaacg acttcataag gaatagatgg
      481 tttgtcataa atcaattata gcagaaagag ggggcataga agaatttata tacaacaaaa
      541 aagtccgacg ggaatcggac tcaaaacaaa aactatttac ttagattata acacaagaga
      601 gaggaaggtt ccatggcaat tgaggtattt ggaccagatt tcagaaagga actacttgca
      661 gacttgattt ctctaaacag agaagcgcta aaaattgctc aattcgagaa ctctaagtca
      721 attgagtggg ttaccatgaa gcggttggaa aaagaaactg gatgggggcg aactaaattg
      781 acccagtgga gagaacaagg gaaatttaac tttaaaaggt catcagaaaa cgggaaagta
      841 ctatatgacc tagcagatgt taatagattt ttgcgaacaa gtggatatga aaaaggagca
      901 taacatgaac aaactagaat tatttttatt agcagcaacc gtcatcttag caatcattgc
      961 aagaattcag tatgaagtca taaaaaaaca taattcgccc gaaaataagc gaaaaatttt
     1021 tagggaagta gctttagaaa acagcaaaag atggagcgag aagcgctcta gaggagaggt
     1081 agaaaaatgc cttttgtaaa acggtagaaa ccacatagtc ctttgacaac tgaatagggt
     1141 accttgaaaa aatattaaaa aagtttgatt ttggggttga cttatgtatc cacataatga
     1201 tattatatat ttgtggatac gaaaggagga aatatgacca ctaccaaaaa acttggtcgt
     1261 ccaacttcta atcctaagtc tcatagcaaa agactgagaa tgacagacga agaagtacaa
     1321 aaattagaat attgtactaa acaaactgga aaaactcaga cagatgtttt gatgctaggc
     1381 ttagataagg tctatcaaga gctaaaaaaa tagcgtataa tccgccatcg ccaaactttg
     1441 gattacacgc tatcgaccga cctgaaaaca ggtacacaaa tatattatca tgtgtaccct
     1501 tttcagtcaa cctgacaagg gtattttttg cgcccttgtt gtttagataa gggtttttat
     1561 tgtacccaaa aataggagga acacaatgga taattcaaaa ctagcaaatc atcaaaaagt
     1621 aacggtagtc tgtacagatt ttaatgtcta tttgaatgga atacgactta ctggagctag
     1681 accagaaacc gctaaattag ctgagagatg cggagagaaa ctcattacac taagtctagt
     1741 agttacagat tttgatgacc atagaacacc taagatggcg gatatggcaa aggaggctga
     1801 gatggctaat aaaacattgg actgggagaa aaagcatttc tataaatcta ataaataatg
     1861 tatctcagag cgttatagat tgattctgga ttttgcgaaa ctccaaattc attaagccat
     1921 tcgataacct cggtttctac ctgcccgata tatccaagaa aatacatgcc ttttggtgtc
     1981 agaccgtcaa ttgtatatat tcgtctatct aatctcggca tttctgtggc agtaactaaa
     2041 tcttgttgga tcaaacaatc tagggtgtaa aaaataattt cttcaacttc tcgataaggg
     2101 tattgagaat atatcctttt tccttcttct gttgcaataa ggtattgaag taaatctaca
     2161 cccgtatcca acttatgata tccgatggct tcaagtgaat ttttgtataa agaatagtaa
     2221 tcaatcatac acttctccaa gtattttatt ttaaatataa caaaatagta agaggaaaac
     2281 aatatggcta aaacttacac attaaccgaa gaagaattga atgaattagt agctgagcgc
     2341 atgaaacaag cgaaagaaaa acgcacacca caaggactat tcaaagatgt cagctttgat
     2401 gatgagttga ttccaatcaa tgaaaaatat ccaaaagtac tcaagaaatt aaatcgtgaa
     2461 cgtgcttata aaccagaaaa acacgtcttc aatcagacac caaaagtttt tggtgtggac
     2521 aacgatatta gttatagcaa aattacaaca catgacgtac acaaccatat tcgtttgctt
     2581 gtcctaaatg tctttggtaa aagtcaaaat aaggaagtat tgcccgagga atatgaccaa
     2641 gcaatagagc tttacaagga attgaaagaa tggtttgtgt ctagctatga taagcgatta
     2701 gagggattgg tgctagaaga tgattaaaaa attctgcgtt aactacttac taagacagat
     2761 taacaaaagc aaactagaaa caagagataa agcgaagtta aaccacttta tcacactagt
     2821 ggactacaag ttaggaggat aaattgggta aagaaaaaac taaaatatac ttttggctaa
     2881 agttcgacaa gaagtttttt gaaaatattt ttatcaaacg tttaaaaaag atggctggcg
     2941 gagacactat gacagtcttg tatattcgtt tgatgctaga aagtttagaa acagactgca
     3001 ttttatatta cgaaggatac tttgaaaatt tggtagaaga gcttgccatc aagttagagg
     3061 tgtctgaaga cgatatcaat atgacattag cttacttcac aaaatgtggt ctaatccaga
     3121 tagacggtag cggtaacgca caaatgcccc aagctaaagc tatgctggaa agtgagacga
     3181 actgggcaaa atataaacga gaaactagaa aaattggaca aattccaacc aatgtccaac
     3241 caatgtccaa ccaatgtcca acagagatag agatagagaa agataaaaag aaagatataa
     3301 atatagatat aaagtcagaa gtagaagaag agataaaaga gatttctact gctgacgaaa
     3361 acagtctcaa aattatatct gattatttcc aacaagaaat cggtattttg tctccaaatc
     3421 agtttgagca gctgtcagac tatattacca ttacaaaaat ggaggtagat gttgttaagt
     3481 ctgctattac aagagctgct gacaattcta aacgttcttt tggttatgtt aactctatac
     3541 tgcgcaattg gcgacaaaat ggaatcacca caatggtaaa agtgaaagaa gaaagtagga
     3601 attttaaagc cagaaaagct aagcaagaag aggtctcaga atatgacact tggtgacaac
     3661 aacgcacttg ctaaaatcgc tgtagcttat caaaaaaatg tcaaaaaaga aagcactgtt
     3721 tgtcaaaaac atggttgcat ctatatcaca atccttaaaa ctggattgac agtatgtccg
     3781 atgtgtcaca aagaggactt agaaagccaa aatgagttac acgtccaaaa gcaatatgag
     3841 agagagcttg aaaacaagcg actgtactat ctcaaaaaat tatcaattat ggacgacgag
     3901 ttggaaaatg cctcatttga taatttcagg gtgatcacac ctaagcagca agaggtcctt
     3961 tcgtgggcaa aatccatggc taattactgg tatacaggag gcaaaggcaa tatcatcatg
     4021 actggtaaag ctggccgcgg gaaaagccat ctagcataca gcatcatcag aggtttgtct
     4081 gacgagacta aaaagttagg gctgcttgta aacattactg acttgctatc agagataaag
     4141 cgagacttta gccaagaggc attttggcta gataagctaa aaaatgttga ttatttggtt
     4201 ttagatgact taggcgccga aaaggtcagc gactggtcca caagtattat ttacagctta
     4261 ctaaataagc gtacaaatac aatcattact acaaacttaa cacctgttga aataaggaaa
     4321 aattatggag aacgtatcgc atcaagaatt agaaaaggct gcgctaagag ccatattatg
     4381 gattttgcag gactggaaga tgagaggatc aagctatgga actaatatta ataacttttt
     4441 ttggcctatc tgaagaacat gcagccaaaa tcatggcgct agacgaagat agccgaataa
     4501 ataaaatcga ggaattgaga gcatggagag aatgctcaaa aataacattt taggaggaaa
     4561 tatgacacca gaagaagcag aaaaagcaaa aatcagagct aaacaagaaa ttgaagtttt
     4621 tagcatatac cttgaacagg cgattgatac ttttggcagc atgctaagcc cacaagaagt
     4681 cttcttggca gcagggtttg cctaccttgg cgctggtcaa acagacatac atgcggccgt
     4741 cgaggggttg tatgagcaag ttcgatgact ttaaatttag cgaagactgg gagagtaact
     4801 actttgaggt ccaagctttg ctaggacaag agatagacaa gctacaaaat agagttgtcc
     4861 agttagcaaa cgaaaataat agattaaagg ccgaaaattg gcagttaaga cacagaaaga
     4921 ggaaatgaaa tggcgaatca attatcaaca tacacacaca aacaattttt taatgcacca
     4981 acaattcaaa aggcttttga tgacgtttgg aaaggcgccg ggacacagtt cgcagtaagc
     5041 atcttgtcag tactacaagg tagtaaaagt ttgaaatcgg catctaatga atctatttat
     5101 gcagcagcta tgaaagcagc cgtgttaaat ctgcctattg agccaagctt aggaagggcc
     5161 tatttagttc cgtacaaagg tcaagcacaa ttccaattag gctataaagg gttgattgag
     5221 ttagcgcagc gcagcggaca atacaaaaat attaatgcag gtatcgtcta taaatcacaa
     5281 ttaatttctt acaacccttt gtttgaggaa ttgatccttg actttagtaa gccacaagat
     5341 gaaattgtag ggtattttgc cgcttttaaa cttttaaatg gattcgagaa agtttctttt
     5401 tggacagtag aaaaagtaac tgcacatgga aagaaatttt caaaatcgtt tgctagcggc
     5461 ccttggaaaa cagactttga tgcaatggct caaaaaacta ttttaaaaga tattttgagt
     5521 aaatatggtc cgttatcagt tgagatgcag aaagctatcg atgaagacaa tcaagattca
     5581 acaatttcta ttccgaaaga cattacacca ccagaaacaa acagccttga cgacctaatt
     5641 ggtcaccaga acgaaaaaaa ggacgctcct ggcaatttaa aagacgtaac tgatgattta
     5701 cattccgagc cagaaaaaac gctcacagac gaaaataaga cggttttaga agacacctct
     5761 tatccagctg atgaaatccc tgattttgac caagaaacag gcgaaattaa agctagcgaa
     5821 ggcaacctct ttgataatct tggagactta atatgattaa acttgtaaaa attgaaggat
     5881 attatattaa tccagaatat gttgttggcg tttgggaaag atctgcttta aattttgacg
     5941 atttagatga aaaagtagtg gttattcaat tcgttggaga tagggaaagg gaagagtgtg
     6001 tcttttacga tacacctatt gatgaagtaa ttaagaggtt gctagatgac tagtttagac
     6061 ttacttggaa aggactatta tagcaaggaa tcagctataa gatactggtc cattagtcag
     6121 tacaagcgct ttagagaatg cgaggcaagg gcacttgctg aattacgagg ggattggaca
     6181 gataccagag ataacactgc gttgctcgtc gggaattacg tccactctta ctttgagggt
     6241 gaggaggctc acgaagaatt taaagtccaa aacagttctg aaatgatttc gaccagagga
     6301 acgacaaaag gccaattaaa aaaggattac ttagtcgctg agcagatgat tgacgctctt
     6361 aaaagcgata acaacttcat ggcaatctac caaggagaaa aggaagttgc catcacagga
     6421 tttcttggtg aggttgagtt taaaggtaag attgactgtc tgaatgctga acgtggctat
     6481 tttgtagaca ttaaaacaac aaaaggacct attgatgaca aaatttggaa tggtcaagag
     6541 cgagtttact ggtttgaggc ttacagctat attttgcaga tggctgccta caaaaacatg
     6601 ctagaggcaa aacacaaaaa gccgtttgag cctatcattt acgcagtaac aaaggaaaca
     6661 ccgccagata ccagagcaat caggattcaa aatttagatg ctatgcaaaa tgagttagac
     6721 aacctagctc aaaacatcaa gcgtttagat gatgttaaaa aaggcataga aaaatctaag
     6781 ccttgtggtc attgcgagta ttgcagggca aatcaattaa cacaaagggt aatgattttt
     6841 taactaacta ttgcaaagtg aagctcggcc tttgcaataa tcatattttc cgagcgagaa
     6901 aggaaaattg caatatcgtc aagttaacag tattgatgat ataaagagtt gctacactcg
     6961 tccttgccaa tgctcacaca caattttagg gcgagtgtgg attttaaaaa aggtgaaaaa
     7021 tatggaacaa attaaaatta caggaacagg aacagcacta attttagata gagtaaaccg
     7081 aatctttgcc atctctggcg gtttgactat gcaatgggat tttattagtg attttaaaaa
     7141 gattgacgac gaaccgtcac ttgatgaaga tggagaacta ttcgaagtag cttacgacct
     7201 tgtgcttgaa gctaaaccca aaactaaaat caatctaaca tcatcatatt ttgctaaaga
     7261 gcataagaaa gacacagacg aaattataaa agtattctcg tttatcgaag ataataagag
     7321 aaatatcttt gaaacccttg gcattcgtgg ggtgcttgaa tgagcaatct agtattatcg
     7381 ctagacatct caacttctgg tacaggttgg gccttattta aaggctcaga ccttatccag
     7441 agtggtgtct taaaacataa gagcgactct tatttcgaac gtggacgata tatggctagc
     7501 caattaagag ctatccagtc acgagca
//
LOCUS       DARYXW010000092         7495 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.092, whole genome shotgun sequence.
ACCESSION   DARYXW010000092 DARYXW010000000
VERSION     DARYXW010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7495
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.092"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            436..975
                     /locus_tag="TV191_001653"
     CDS             436..975
                     /locus_tag="TV191_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508145.1"
                     /translation="MRQLIAAMVEKNQDLPRNILVAEMSLEKAVQPDDYRVKDYRNLR
                     QIRLTTSGLVLEVRLLKGLPARWLKKDTSAKPSKAVNSRALAEHSHVLSVNQAALQQF
                     LAETGDQNPLHQTAPYILPGALLMEEVSSWLTLDYRRLSLRFYAPAVVNAPIHLVMRE
                     KAISLYQAGELVAKGELHV"
     gene            972..2087
                     /locus_tag="TV191_001654"
     CDS             972..2087
                     /locus_tag="TV191_001654"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase"
                     /protein_id="HEL1508146.1"
                     /translation="MIDVYIQRGLRTPIGLAGKQFARVRPELLGAQLINALVKADKLA
                     IDEVICGNAVGTGGNIGRLMTLYSDLGETVPAITVDMQCASAGAALTMGYAKIKAGLA
                     TSLLAGGIESSSLQPQRIYAAADSRSGAYQVAQFSPDTSSQLAMIAGAERVAQAYQMT
                     PSQLNQWTLTSHQRAHIARQKHWLADIILAMPGMSDQGIRPRLSEKVLSKVPPILDKA
                     GLISAANTCLTHDAAAFLVLSNQRSAYQILDLVEVAGNPKTSPQMVVEASQVLLARNG
                     LAMTDMDAIEWNEAFAVIDLLFEHYFVEALDRYNIFGGALAYGHPFGASAAIIILHLM
                     QALALKQGKYGLAAIPAAGGQAFALLLEYHKDYSHAI"
     gene            2077..3339
                     /locus_tag="TV191_001655"
     CDS             2077..3339
                     /locus_tag="TV191_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HEL1508147.1"
                     /translation="MLSRLLAWASQAPQRPAILTDQKTLTYQDLVEQILAYQPQESIS
                     YPTLIVKRDCFQQLIAFCYHLQHGNYPLICHPNLPEQEQRRLSSCDPPSDKAAFAVLS
                     SGSTGRPKVFWRSWASWSNFFEQQNQLFYFSEQTRLFSHGSLSFTGNLNLALAQLWAG
                     GCLVFSDQRSFKGWSSVWRRQKVTHLYLLPSLLQRLLPYFSADSYFAPYLLTSSQHLS
                     PELIRSYYQRFPRLELLMFYGASELSFISWCQGFEAMAIAGFVGRPFPQVKLELREGH
                     IFVQTPYAIEGIEQPYSVDDVGEMTAAGLILKGRTKDWVNQQGVKCHLPSLVQLVHQS
                     GVVQEAAAIKGGSSAADEHVILCLVLKKQGSLTAVKAYLEAHLSPAQRPKRYILLKEL
                     PLNDSGKLDSRRLSQLAHKSTKAAHNTK"
     gene            3385..4404
                     /locus_tag="TV191_001656"
     CDS             3385..4404
                     /locus_tag="TV191_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEL1508148.1"
                     /translation="MVKKGGQLMKQDMLARYQALKPYVRAGLSSTSQQLLAAASAIDA
                     RLGSPTFLAIWQCEKQCRSPKELLGLVLDLVGMPIELSGRLEDTQALLSRFYPDLPPD
                     HCFWVELAQMVSLAFPDKELAQQSALAKGLHQLRYLISSQQAQYIRSHFRSEDMTDAQ
                     ALAIFLKDKKGPAFWRSQPDYTLMESARLHNKLKLVNGLASFPDHEISHNIKILLHFH
                     TEFILDSQGCFLNEIDGEVVTNKGIINGASFNYGTAGKRHWELDVAPISRHDPTFRKK
                     CLVGHQAPKWLKRSWLQLSPLDFDYSYFNAKGFFSLNSKSCFALVKRQARAFRWQIWR
                     SRFFK"
     gene            4603..5313
                     /locus_tag="TV191_001657"
     CDS             4603..5313
                     /locus_tag="TV191_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019321978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1508149.1"
                     /translation="MKKILIVDDEKPISDIIKFNLTKEGYDTVTAFDGKEAVAVFEEE
                     KPDLIILDLMLPELDGLEVAKEIRKTSHIPIIMLSAKDSEFDKVIGLEIGADDYVTKP
                     FSNRELLARVKAHLRRTETIETAVAEENASSGSQELTIGNLQILPDAFIAKKHGQEVE
                     LTHREFELLHHLANHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSR
                     PEYILTRRGVGYYMKAYD"
     gene            5306..6658
                     /gene="vicK"
                     /locus_tag="TV191_001658"
     CDS             5306..6658
                     /gene="vicK"
                     /locus_tag="TV191_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEL1508150.1"
                     /translation="MTKDIIGNLSAFELAILLLLVFVAFYFIHLAIRDYRNARIIRLM
                     SHKIRDLINGRYTDTINEKADIELMELSEQLNDLSDVFRLTHENLAQEKNRLASILAY
                     MTDGVLATNRSGKIIMINETAQKQLNLNREQALEKNITDLLDSDSPYTYRELVSKTPI
                     VTLNRRNDTGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALKEDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNHVT
                     QLSVEMTNFTAFMTSILNRFDLVKNQHTSTGKSYEIVRDYPITSIWLEIDNDKMTQVI
                     ENILNNAIKYSPDGGKIIVNMKTTDTQLIISISDEGLGIPKKDLPLIFDRFYRVDKAR
                     SRAQGGAGLGLAIAKEIIKQRRGFIWAKSDYGKGSTFTIVLPYEKDAAIYDEWEDDID
                     "
     gene            6662..7471
                     /locus_tag="TV191_001659"
     CDS             6662..7471
                     /locus_tag="TV191_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEL1508151.1"
                     /translation="MSEVGFKYSILASGSTGNCFYLETPKKRLLIDAGLTGKKITSLL
                     AEIDRRPEDLDAILITHEHSDHIKGVGIMARKYNLDVYANEKTWQMIDERHMIGNLDV
                     AQKHVFERGKTMTFGDIDIESFGVSHDAVDPQFYRIMKDNKSFVMLTDTGYVSDRLAG
                     IIENADGYLIESNHDVEILRAGSYPWSLKQRILSDLGHLSNEDGAGAMIRSLGNKTKK
                     IYLGHLSQENNIKELAHMTMVNQLAMADLGVGTDFTVHDTSPDTACPLTDI"
BASE COUNT         2020 a         1599 c         1798 g         2078 t
ORIGIN      
        1 cctcggcacg atagtcctga acccttgttt cagcctactt cttcactgtc ctaagatcgc
       61 ttttaggatg gccttgccaa gtctaggcct tagttggagt accgtaacat tcgcagcagc
      121 ctttatcagc taatgtctta gaatgataat aggtcatgcg acttatctag cgcgtgaatg
      181 accttgaagc ttgccttgtg tgctttcttc tgtctatttc aagtagagct gaatgactat
      241 cagttacctg taggcagagg ctgtagcagc cttgatttat taaatgatat tgaacatgat
      301 gtgatcagac aaaaaaggtt aggctaaagg ctcgcctttt tttgctaact aagccttgtt
      361 tttgctgttt tttcttttct tgtgttcagg tattcagtat aataaagtta acttgttcgc
      421 aaaaggatgg ttacaatgag acagctaatc gcagctatgg ttgagaaaaa tcaggattta
      481 ccaagaaaca tccttgtggc tgagatgagc ttggaaaaag ctgtgcagcc agatgattat
      541 cgcgtaaagg attatcgaaa tctgcggcag atcagattga ctacatcagg gcttgtgcta
      601 gaggttcgat tactaaaagg gctaccagcc aggtggctga aaaaggacac aagtgctaag
      661 ccttctaaag cagttaatag ccgagcatta gctgagcata gccatgtact gagcgttaat
      721 caggcggcct tacagcaatt tctagcagaa acaggagatc aaaatcctct tcatcaaaca
      781 gctccctata tcttaccggg agccctcttg atggaagagg ttagcagctg gcttacttta
      841 gattaccgta ggctaagcct gcgtttttat gccccagcgg ttgtgaatgc tcctattcac
      901 ctagtgatga gagaaaaagc tatcagcctc tatcaggcag gagaattagt cgcaaaagga
      961 gagcttcacg tatgattgat gtctacattc aaagagggct tagaacgcct attggtctag
     1021 ctggcaagca atttgctagg gtgcgtccag aactgcttgg tgctcagctg attaatgcct
     1081 tagtcaaagc agataagctg gctattgatg aggtgatctg cggtaatgct gttgggacag
     1141 gcggtaatat tggccggctg atgactctgt attctgactt gggagagacc gtacctgcca
     1201 taaccgttga catgcaatgt gcctcggctg gtgcagctct tactatgggc tatgctaaaa
     1261 tcaaggcagg tcttgccact agcttgttag caggagggat cgaaagcagc tctttgcagc
     1321 ctcagcgtat ctatgctgct gctgatagcc gatcaggtgc ttatcaggta gctcagtttt
     1381 caccagatac cagtagccag ctggctatga tagcaggagc agagcgggtg gctcaggcct
     1441 accaaatgac cccctcacag ctcaaccagt ggacccttac tagccaccag cgagcacaca
     1501 tagctaggca gaagcattgg ttagctgata ttatattagc aatgccagga atgtctgatc
     1561 aaggcattcg ccctcgcctg tcagaaaagg tcttgagcaa ggtgccgccg atacttgata
     1621 aggctggcct catcagtgct gctaatacct gcttgaccca tgacgcagca gcatttttag
     1681 tgctaagcaa tcaaagatca gcctatcaaa tccttgatct tgttgaggtt gctggcaatc
     1741 ctaaaaccag tcctcaaatg gtggttgagg ccagtcaggt cttattagct agaaacggcc
     1801 tagccatgac ggatatggat gcgatcgagt ggaatgaagc ttttgcagtg attgatctgc
     1861 tttttgagca ttattttgtg gaggcccttg atcgctacaa tatttttgga ggcgctcttg
     1921 cctacggtca tccctttggc gcgtcagcag ccattatcat tttgcatcta atgcaggctt
     1981 tggccttaaa gcaaggaaag tatggtttag cagccattcc agcagctggt ggtcaagcct
     2041 ttgccctgtt attggaatat cataaggact actcacatgc tatctagact gctagcttgg
     2101 gcaagccaag caccacaaag acctgctatc ctaacagacc aaaaaaccct aacctatcag
     2161 gatcttgtag agcagatctt ggcttatcag cctcaggagt ctatctccta tccgaccctg
     2221 attgtcaaaa gggattgctt ccagcagctg attgcttttt gctatcattt gcaacatgga
     2281 aactacccac ttatctgtca cccaaatcta ccagaacaag agcaaaggcg tctgtctagc
     2341 tgcgatcctc catcagacaa ggcggctttt gcggtgctta gctctggctc tactggccgt
     2401 cccaaggttt tttggcgctc ctgggcttct tggtctaatt tttttgagca gcaaaaccag
     2461 ctgttttatt tctcggagca aacaaggcta tttagccatg gaagcttgag ctttacaggc
     2521 aatttgaact tagctctggc gcagctctgg gccggaggct gtctggtctt tagtgatcag
     2581 cggtccttta agggctggtc ctctgtttgg cgcaggcaaa aggttactca tttatatctc
     2641 ttaccgagtc tgctacagcg gctactgcct tacttttctg ctgatagcta ttttgccccg
     2701 tatttattaa cctcatctca gcacttgtca ccagagctga ttcgcagcta ttaccaacgc
     2761 tttccgcggc ttgagttgtt gatgttttac ggtgccagtg agctttcctt tatcagctgg
     2821 tgtcagggct ttgaggctat ggcaatagct ggctttgtag ggcgtccctt tcctcaggta
     2881 aagctggagc tccgagaggg gcacattttt gttcagactc cctatgccat tgagggcatt
     2941 gagcagccct atagtgtcga tgatgtgggg gaaatgacag cagcaggctt gattctaaag
     3001 gggcgaacca aggactgggt gaatcagcaa ggtgtcaaat gccatcttcc tagccttgtt
     3061 cagctagtcc accagtcagg agttgttcaa gaagcagcag cgataaaggg tggcagcagt
     3121 gcagctgatg agcatgtgat cctgtgcttg gtgttgaaaa agcagggaag ccttaccgct
     3181 gttaaggcct atcttgaggc gcacctaagc ccagctcaga ggcctaaacg gtatatactc
     3241 ttaaaggagc taccacttaa tgacagtgga aagcttgata gcagaaggct tagccagctc
     3301 gcccacaaat caactaaagc tgctcataac accaaataag gaaaagtcac ctgagcccaa
     3361 agcatcagct caatatggta taatatggtc aaaaaaggag gtcagttgat gaagcaggat
     3421 atgttagcac gttatcaggc actcaagcct tacgtaagag caggtctttc ctcgacctct
     3481 cagcagctat tggcagctgc ctcagctatt gatgctcgct taggctcacc gaccttttta
     3541 gccatttggc agtgtgaaaa acagtgtcga tctcccaagg aattactagg gcttgttcta
     3601 gatcttgtcg gcatgccaat agagttatcc ggaaggctag aggatacgca ggctctgctg
     3661 agtcgctttt atcctgactt gccaccggat cattgctttt gggtggagct agcccagatg
     3721 gttagtcttg cttttccgga taaggagcta gcgcagcaga gcgcgttagc taagggtctt
     3781 catcagcttc gctatctcat ttcgagccag caggcacaat atattcgcag ccattttaga
     3841 tcagaggaca tgactgacgc tcaggcactg gctatctttc tcaaggataa aaaaggccca
     3901 gctttttggc gcagccagcc tgactacacg cttatggaat cggctcgtct gcataacaag
     3961 ctaaagcttg tcaatggatt agcaagcttt cctgatcatg agatttccca taatattaaa
     4021 attctgttgc atttccatac cgaatttatc ctcgatagtc aggggtgttt tcttaatgaa
     4081 atagatggtg aagtggtgac caacaaggga atcattaacg gagcctcctt caattatggc
     4141 acagcaggca agaggcattg ggagctagat gttgctccta tcagccgaca tgacccgacc
     4201 tttaggaaaa aatgcttagt aggccaccaa gctcctaagt ggctgaagcg ctcttggctt
     4261 cagttatcgc cactagattt tgactattct tattttaatg ctaagggctt ttttagcctc
     4321 aatagcaaaa gctgctttgc cttggttaag cgacaggcac gtgcctttag atggcagatc
     4381 tggcgtagca gattttttaa gtaatggatc agtagctggc ttgcttgatg aggtatttag
     4441 agagcgtttt tgtggctagt atagtggtca ttgtcaattt ctcctaaatt ttgatataat
     4501 caaaaggaca taataaaatg atcggtctcg tctctaaatc cttatggaat agggattagg
     4561 cagcgtagca attaatgaag agaaatgttc tgaggtataa gcatgaagaa aatactgatt
     4621 gttgatgatg aaaagccgat ttctgatatc attaaattta atctgacaaa ggaaggctat
     4681 gatacggtca cagcatttga tggcaaagag gccgttgcag tctttgaaga ggaaaagcca
     4741 gatttgatta ttttggattt gatgcttcct gaattagatg gccttgaggt agccaaggaa
     4801 atccgcaaga ccagccatat tcctatcatc atgctatctg ctaaggatag cgaatttgat
     4861 aaggtgattg gacttgaaat aggggccgat gattatgtga ctaagccctt ttcaaatcgt
     4921 gagctgctgg cgcgtgtcaa ggcacatttg cgtcggacag agactattga gacagcagta
     4981 gccgaagaaa atgcctcctc aggctctcag gagctaacca tcggcaatct acagatttta
     5041 ccagatgcct ttatcgctaa aaagcatggt caagaggttg agctgaccca tcgtgagttt
     5101 gaattgctgc atcatctggc aaaccatatc ggacaggtca tgacacgtga gcatttgctt
     5161 gagaccgtat ggggctacga ttattttggc gatgttcgaa ccgttgacgt tactatccgt
     5221 cgcctgcgcg aaaaaataga ggatacaccg agtcgtccag agtatatttt gacaagacgt
     5281 ggtgttgggt actacatgaa ggcttatgac taaggacatc attggaaacc tttctgcatt
     5341 tgagctagcc atactcttat tgcttgtttt tgttgctttt tatttcattc atttagccat
     5401 tcgtgattat cgcaatgctc ggatcattcg tctgatgagc cataagataa gagatttgat
     5461 caatggtcgc tatactgata cgatcaatga aaaggctgat attgaattga tggagctgtc
     5521 tgagcagctc aacgacctat cagatgtttt tcgtctgacc catgaaaacc ttgcccaaga
     5581 gaaaaatcgt cttgctagta ttttggctta tatgacagat ggggtccttg cgaccaatcg
     5641 ttccggcaag attatcatga ttaatgagac tgctcaaaag cagctcaatt taaatcgtga
     5701 gcaggcgctg gaaaaaaaca ttacagattt attagacagt gactcacctt acacctaccg
     5761 agagctggtc tcaaaaacac cgattgtgac cttaaatcgt cgtaatgaca caggagagtt
     5821 tgtttcgctg cggctgcgtt ttgcgcttaa taggcgagag agcggcttta tttcaggtct
     5881 agttgttgtg cttcatgaca cgactgagca ggaaaaggag gagcgtgagc gcagactctt
     5941 tgtctcaaat gttagccatg agcttcgcac acctttgacc tctgtcaagt catacctaga
     6001 ggctctagat gagggcgcgc taaaggagga catagcccca agctttataa aggtctcact
     6061 agacgaaacc aatcgcatga tgcgcatgat ttcagatttg ctcaatctat caagaattga
     6121 taatcatgtg acacagctgt ctgttgaaat gaccaacttt acagccttta tgacctctat
     6181 cttaaaccgc tttgatttgg tgaaaaatca gcacaccagt acaggaaaat cctatgaaat
     6241 tgtcagagat taccctatca cctctatttg gctagaaatt gataacgata aaatgacgca
     6301 ggtcattgaa aatattttaa acaatgccat caaatattca cctgatggtg ggaaaattat
     6361 cgtaaacatg aaaacaacag atacccagct aatcatttcg atttctgatg agggattggg
     6421 cataccaaag aaggacctgc ctttgatttt tgaccgtttt taccgagtgg ataaggctag
     6481 aagtcgggcg cagggggggg ccggcttagg gctggctatt gctaaagaaa ttattaagca
     6541 gcgccgcggc tttatctggg ctaagagtga ctatggcaag gggtcaacct ttaccattgt
     6601 gttaccttac gaaaaggatg ctgctatcta tgatgaatgg gaggatgata ttgattaatt
     6661 gatgagtgag gttggcttta aatatagtat tttagcatca ggatcgacag gtaactgctt
     6721 ttacttggaa acgcccaaga agcgactgtt gattgatgca ggactgactg gaaagaaaat
     6781 caccagtctt cttgctgaga ttgacagaag gcctgaggat ttggatgcta tcttgattac
     6841 ccacgagcat tccgaccata tcaagggtgt tggaatcatg gctcgaaaat ataacctaga
     6901 tgtctatgcc aatgaaaaga cttggcagat gattgatgag cgtcatatga ttggcaacct
     6961 agacgtcgca caaaagcatg tctttgaaag aggtaagacc atgacctttg gagacattga
     7021 cattgagagc tttggtgtta gtcatgacgc tgtagaccca cagttttacc gcattatgaa
     7081 ggataacaag tcctttgtca tgctgacgga tacaggatat gtgagcgacc gcttggctgg
     7141 gatcattgaa aatgctgacg gctacttgat tgagtcaaat cacgatgtgg agatattgcg
     7201 agccggctct tatccttgga gcctcaagca gcgaatctta tctgacctag ggcatttatc
     7261 caatgaagat ggtgctggcg ctatgattcg aagcttgggc aataaaacaa agaaaatcta
     7321 cctcggtcac ctaagccagg agaacaatat caaagaatta gcacacatga caatggtcaa
     7381 tcagctagca atggcagatt taggtgttgg aacagatttt actgttcatg acacctcacc
     7441 agataccgcc tgtcccttga cagacatcta gccttatgac ttcacccctg cttgt
//
LOCUS       DARYXW010000093         7383 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.093, whole genome shotgun sequence.
ACCESSION   DARYXW010000093 DARYXW010000000
VERSION     DARYXW010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7383)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7383)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7383
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.093"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(308..2950)
                     /gene="adhE"
                     /locus_tag="TV191_001660"
                     /gene_synonym="adhC"
     CDS             complement(308..2950)
                     /gene="adhE"
                     /locus_tag="TV191_001660"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEL1508152.1"
                     /translation="MTEKNSTVETTSVAATIDALVQKGLVALDKMRQLTQEQVDYIVA
                     KASVAALDAHGELAKHAYEETGRGVFEDKATKNLFACEHVVNNMRHQKTVGIIEEDDV
                     TGLTLIAEPVGVICGITPTTNPTSTAIFKSLISLKTRNPIIFAFHPSAQESSAHAARI
                     VRDAAIAAGAPEDCVQWIETPSLEATNALMNHDGIATILATGGNAMVKAAYSCGKPAL
                     GVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVSEFKS
                     YHTYFVNKKEKALLEEFCFGAKANSKNCAGAKLNPNIVGKPAAWIAEQAGFTVPEGTN
                     ILAAECKEVSENEPLTREKLSPVIAVLKAESRTDGVEKARQMVEFNGLGHSAAIHTAD
                     ADLAKEFGTKIRAIRVIWNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVSAVN
                     LLNIKKVGRRRNNMQWFKVPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGFLDR
                     IIEQLDLRRNKVVYQIFADVEPDPDITTVMKGTELMRTFKPDTIIALGGGSPMDAAKV
                     MWLFYEQPEVDFHDLVQKFMDIRKRAFKFPELGKKTKFVAIPTTSGTGSEVTPFAVIS
                     DKANNRKYPIADYSLTPTVAIVDPALVLTVPGFIAADTGMDVLTHATEAYVSQMANDF
                     TDGLALQAIKIVFENLEKSVKEADFESREKMHNASTMAGMAFANAFLGISHSMAHKIG
                     AQFHTVHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIAKLLGLPASTP
                     EEGVESYAKAVYDLGCRLGIKMNFRDQGIDEEEWKAHTRELAYLAYEDQCSPANPRLP
                     MVEHMEEIMNDAYYGYAERPGRRK"
     gene            complement(3370..5151)
                     /locus_tag="TV191_001661"
     CDS             complement(3370..5151)
                     /locus_tag="TV191_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEL1508153.1"
                     /translation="MRIKWFSFIRVTGLLLVLLYHFFKHTFSGGFVGVDIFFTFSGYL
                     ITALLIDEYVSKQTIDVVAFFRRRFYRIVPPLVLLILLTIPFTFLVKSDFIAGIGQQI
                     AAALGFTTNSYELLTGSSYESQFIPHLFVHTWSLAIEVHFYLLWGLLVWLLAKKGYSQ
                     KKFRGILFLISSAVFTLSYFSMFIRAFFVSDFSSVYFSTLSHSFPFFLGAMFATMTGI
                     KDTTVRFQKNVKLWPRLHVIGVMAGAFALLLFLTLVLDFNHIFTYLFGFVLASLFASV
                     MIYAARVLSDQTPTWQEPLLVTYLADISYGIYLFHWPFYIIFTQLMSNWLAVILTVFF
                     SVVFSTLSYYIIEPLIQGKTPQLFGLAIDCNPYKKWLSGLALGLFLLMVGTCLTAPRV
                     GNFETQLLVDSLQQSQSNLNKTHTLAAGDAHALSDVSIIGDSVALRSSDAFSKLMPTA
                     QLDAAVSRNFSEAFELFENHIQSKSLSKTTVLAVGVNSLYNYAQDIQGFIYALPKGHR
                     LVIVSPYDAKNAAQVAEAREHLLQLAKKYSYVTVADWYKAAVENPNIWYGSDGVHYNN
                     DAKLKGADLYVSTIQAAVERAAKKDAK"
     gene            complement(5148..5549)
                     /locus_tag="TV191_001662"
     CDS             complement(5148..5549)
                     /locus_tag="TV191_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508154.1"
                     /translation="MKAIINNIQKWQITRTKLEIISVLVIIVCGLSVFTLTISSKASL
                     TYDNGQIKYTGYVLNHRMNGKGKLVYPNGDTYVGDFNKGVFDGEGTFTASTGWSYSGQ
                     FKKGQADGKGTLKAKDSKVYKGTFKQGIFQK"
     gene            complement(5555..6013)
                     /locus_tag="TV191_001663"
     CDS             complement(5555..6013)
                     /locus_tag="TV191_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEL1508155.1"
                     /translation="MKKVCFVCLGNICRSPMAEFVMKSMASPDELQVESRATSGWEHG
                     NPIHHGTQSLLQQYQISYDTKKTSQQITSFDFEAFDYIIGMDSHNIRDLKQMSKHQWD
                     SKIHLFIEGGVPDPWYTGDFEETYRLVKAGCQHWLSQISAEHESHVEIDE"
     gene            complement(6254..7261)
                     /gene="ruvB"
                     /locus_tag="TV191_001664"
     CDS             complement(6254..7261)
                     /gene="ruvB"
                     /locus_tag="TV191_001664"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEL1508156.1"
                     /translation="MTRILDNDLIGDEGSVERTLRPQYLREYIGQDRVKDQLMIFIEA
                     AKRREESLDHVLLFGSPGLGKTTMAFVIANELGVHLKQTSGPAIEKAGDLVAILNDLE
                     PGDVLFIDEIHRMPMAVEEILYSAMEDFYIDIMIGAGDTSRSVHLELPPFTLIGATTR
                     AGMLSNPLRARFGITGHMEYYQTADLTEIVERTADIFDMTIKHEAAYELARRSRGTPR
                     IANRLLKRVRDYAQIMGDGMITTQITDKALTMLDVDQEGLDYVDQKILRTMIEVYQGG
                     PVGLGTLSVNIAEERDTVEDMYEPYLIQKGFIMRTRTGRVVTEKAYQHLGYPYEKTIK
                     T"
     gene            complement(7295..>7383)
                     /locus_tag="TV191_001665"
     CDS             complement(7295..>7383)
                     /locus_tag="TV191_001665"
                     /inference="COORDINATES: protein motif:HMM:NF038244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="quorum-sensing system DWW-type pheromone"
                     /protein_id="HEL1508157.1"
                     /translation="YQYYLFLAALFLLHSAQLLSDIDWWRVG"
BASE COUNT         2271 a         1645 c         1356 g         2111 t
ORIGIN      
        1 gttttattag aaaataaagc tcatcagata gacgcaacat gttattttct tcagctaatt
       61 gctaagtgca gctaagtcgt aactatcagc cactttatga atatggcaaa tgaagcttcc
      121 ccctctgatg gaatgctctg taaaaccatt gtcttaaaag ctttatatga tatctgagaa
      181 actacccctg agttaagcta tctcaacaca aggcactgcc gactttttca tctaacacag
      241 cccttttcat agctagataa aaaaatagaa gccaagcagc tcctattttt actattaatg
      301 attgatatta tttccgacgt cctggacgct ctgcgtaacc ataataagca tcattcatga
      361 tttcttccat gtgctcaacc attggcaagc gtgggttagc aggtgagcat tgatcctcgt
      421 aggcaagata agcaagctca cgagtgtgtg ccttccattc ttcctcatca attccttgat
      481 ctctgaaatt catcttaatg cctaagcgac agccaagatc ataaacagct ttagcataag
      541 attcaacacc ttcttctgga gtagatgccg gaagtcctag caacttagca atgtcttgat
      601 atttttcatc ggcgcgatag taattgtact taggccatgt tgctgtttta gcaggacggg
      661 taccattgta acgaataacg tatggaagca agatagcatt ggtacgtcca tgaacagtat
      721 ggaattgtgc accaatctta tgagccattg agtgagaaat acccaggaag gcattagcaa
      781 aggccatacc tgccattgtt gaggcattat gcattttttc acgtgactca aagtcagctt
      841 ccttaacaga tttttcaagg ttttcaaaga caatcttaat ggcttgaagg gccaaaccat
      901 ctgtaaagtc attagccatt tgtgatacgt aagcctcggt tgcgtgggtc aacacgtcca
      961 tacctgtatc agctgcaatg aagcctggta ctgtaagcac caacgccggg tcaacaatgg
     1021 ctaccgttgg tgtcaatgaa tagtcagcaa ttgggtactt gcggttgttg gccttatctg
     1081 agataacagc aaacggtgta acctctgatc ctgtacctga ggttgttgga atagccacaa
     1141 attttgtttt cttaccaagc tcagggaact tgaaggcacg tttacgaata tccatgaatt
     1201 tttgaacaag atcatggaag tcaacctctg gttgctcata gaataaccac attacctttg
     1261 cagcgtccat tggagaacca ccgccaagag cgataatcgt atctggcttg aaggtacgca
     1321 tcagctcagt acctttcata accgttgtga tatcaggatc tggctcaaca tctgcaaaaa
     1381 tttgataaac aaccttatta cgacgaaggt caagctgctc gatgatacga tctaagaagc
     1441 caagctcaac catagcgtgg tcggtaacaa tcatcacacg ctcaacgtca cgacattttt
     1501 gaaggtattg aattgaatca cgctcgaagt atgtttttga aggaacttta aaccattgca
     1561 tattatttct acgtcttcct acttttttga tgttcaagag atttacagca ctaacattat
     1621 caccaactga gttacgtcca taagaaccac agcccaatgt taatgacggt aggaaggcat
     1681 tataaacatc accgatacca ccaaatgtag aaggtgaatt ccaaatcaca cgaatagcac
     1741 gaatttttgt tccaaattcc ttagctaagt ctgcatcagc agtatgaata gcggctgagt
     1801 gaccaagtcc gttaaattca accatttgac gagccttttc aacaccatct gtgcgagatt
     1861 cagccttcaa aacagcgata actggtgaca atttttcacg tgttaatggc tcattttcag
     1921 aaacttcctt acattctgct gcaaggatat tcgttccttc tggtactgta aagcctgcct
     1981 gctcagcaat ccaagctgct ggcttaccaa caatattagg gttcagctta gcacctgcac
     2041 agtttttact gttagcctta gcaccaaagc agaattcctc taacagagcc ttttcctttt
     2101 tgttgacaaa gtaagtgtgg taagacttaa attcactaac aaactcgtca taaatctcct
     2161 tgtcgataat aacagcctgc tcagaagcac aaaccatacc attgtcaaat gatttagaca
     2221 tgacaatatc gtgtgctgcc tgacgaatgt tagcggattt ttcaacatag gcaggcacgt
     2281 taccagcacc aaccccaaga gctggcttac cacatgagta ggctgcctta accatagcat
     2341 taccaccagt tgcaaggatt gttgcaatac catcatgatt catcagagcg ttagttgctt
     2401 ctagtgatgg ggtttcaatc cattgaacac agtcctcagg agctcctgct gcaatggctg
     2461 catcacgaac aatgcgtgct gcatgagctg atgattcttg agctgatggg tggaaggcaa
     2521 aaataatagg gttacgtgtt tttaaggaga ttaaagattt aaaaatagct gttgacgttg
     2581 ggttagttgt tggggtaatc ccacaaataa cacctactgg ctcagcaatt aaggtcaaac
     2641 ctgttacatc gtcttcttca atgataccta ctgttttttg gtgacgcatg ttattaacaa
     2701 cgtgctcaca tgcgaaaagg tttttggtag ccttatcttc aaaaactccg cgaccagttt
     2761 cttcataggc atgcttagct aactcaccat gtgcgtccaa agcagcaaca gaggccttcg
     2821 ctacaatgta gtcaacctgt tcttgagtta actgacgcat tttatcaagc gctactaaac
     2881 ctttttgaac aagagcgtca attgttgcgg caacagatgt tgtttcaaca gtactatttt
     2941 tttcagtcat ttgagactcc tttaccttgt taaaagtttc acaattttgt ttacaaaaat
     3001 attatatcat tttttggcat tttgtaaatc atttcacaat aaaattgtga tgttttttca
     3061 atcaatttcc gaaactcttt gataacaagg ggtttggctt ggtggatttt ttctgaaata
     3121 atggctgacg cattcacttt gttccgaaag cgctttcttt tttagatcag gctaaattat
     3181 ttaatgatcc gtttttaaaa gcacgtcacc gtcagcaata acagccaata atgacactgt
     3241 ctaacaggtg gagctttatc tcgcgctaaa gggcgcaaga cgatctaaaa atcacatcat
     3301 gaaaaggctt gatctgtttg taagaccaag ccttcgttat taattcttaa caaattgttg
     3361 ttagcaccac tatttagcat ctttttttgc tgctcgctca acagccgcct gaatcgttga
     3421 gacatataag tcagcacctt ttaatttggc gtcgttattg tagtggaccc catcactacc
     3481 ataccagata ttgggatttt cgactgccgc cttgtaccag tcagcaactg ttacatagct
     3541 atatttttta gctagctgca acaaatgctc tctagcctct gctacctgtg ctgcattctt
     3601 agcatcatag ggcgacacaa tcaccaagcg atgccccttt ggtagtgcat aaataaagcc
     3661 ttgaatatcc tgcgcataat tataaagaga attaacacca acagctaaaa ccgttgtttt
     3721 tgataagctc ttggattgga tatgattttc aaaaagctca aaggcttcac tgaaattgcg
     3781 gctgacagca gcgtctagtt gagcagtcgg cattaatttt gaaaaagcgt cactagacct
     3841 caaggcaact gagtcaccaa taatgctaac atcactaaga gcatgcgcat ctcctgctgc
     3901 caaagtatgt gtcttattga gattactttg agattgctgc aaggaatcta ctaaaagctg
     3961 ggtctcaaaa ttaccgaccc ttggtgctgt caaacaggta ccaaccatca acaaaaagag
     4021 tcctaaagca agccctgata accatttctt atagggatta caatcaattg ctaaaccaaa
     4081 aagctgtggt gtcttgcctt gaatcaaagg ctcaataatg taataagaaa gcgttgaaaa
     4141 cactactgaa aagaaaaccg ttaagatcac tgccagccag ttagacatca gctgtgtaaa
     4201 aataatgtaa aatggccaat ggaataaata aatcccatag ctaatatccg caagataggt
     4261 cacaagcagt ggttcctgcc aggttggtgt ttgatcgctc aaaacacgcg cagcataaat
     4321 cattaccgaa gcaaaaagac tggctaagac aaaaccgaaa agataggtaa agatatggtt
     4381 aaaatctaac acaagcgtta gaaacaacaa cagagcaaaa gcgccagcca tcactccaat
     4441 aacatgtagc cttggccaca gcttaacatt cttttgaaag cgaacagtcg tgtccttaat
     4501 tcccgtcatg gttgcaaaca tcgctcctaa aaagaaagga aagctgtgtg aaagcgttga
     4561 aaagtaaaca gaagaaaaat ctgatacaaa gaaggctctg ataaacatgc tgaagtagct
     4621 aagcgtgaac actgcggaag aaattaaaaa cagaatgcct ctaaatttct tctgactgta
     4681 gcctttttta gctaataacc aaaccaacag cccccaaagc aaataaaaat gcacctcaat
     4741 ggccaagctc caggtatgca caaacagatg cggaatgaat tgactttcat agctactgcc
     4801 tgtcagtagc tcataactat ttgttgtaaa ccctagggca gctgctattt gctgaccgat
     4861 accagcaatg aagtcacttt tgactaaaaa agtaaaggga attgtcaaga gaattaacaa
     4921 gacaagcggc ggtacaatac gataaaaacg ccttctaaaa aaagcaacca catcaatggt
     4981 ttgttttgag acatattcat caatcaacaa ggctgtaatc aaatagcctg aaaaagtaaa
     5041 gaagatgtca acgccaacaa agcctcctga aaaagtatgc ttaaaaaagt gatagagcaa
     5101 caccagcaaa agacctgtta ccctaataaa cgaaaaccat tttatcctca tttttgaaat
     5161 atcccctgct taaaggttcc tttgtaaacc tttgaatcct tcgccttcaa agtacccttg
     5221 ccatcagcct gacctttttt aaattgtccg ctgtaagacc accctgtact agctgtaaac
     5281 gttccttctc catcaaagac acctttatta aaatccccaa cataggtatc gccattaggg
     5341 taaaccaatt tccctttacc attcattcta tgattaagga catagccggt gtacttgatt
     5401 tgcccattgt cataggtcaa gcttgctttt gaggatatgg tcaaggtaaa aaccgacaat
     5461 ccacagacaa taatcacaag gactgaaata atctctagct ttgtccgagt gatctgccat
     5521 ttttgaatgt tatttattat tgctttcatt actattactc atctatttcc acatgtgatt
     5581 catgttcagc gctgatttga ctcaaccaat gctgacagcc cgctttaacc aagcggtagg
     5641 tttcttcaaa atctcctgta taccaaggat ccggaacgcc tccttcaata aaaagatgga
     5701 tcttggaatc ccactgatgc ttggacattt gcttcaaatc tctgatatta tggctatcca
     5761 ttccgataat atagtcaaag gcttcaaagt caaagctggt gatttgctga gaggttttct
     5821 tggtatcata gctaatctga tattgctgta atagcgattg tgtcccatga tgaattggat
     5881 tgccatgctc ccagccagag gttgcacgac tctccacctg tagctcatca ggactggcca
     5941 tacttttcat gacaaattcg gccataggac tacgacaaat atttccaaga caaacaaagc
     6001 atactttttt catgaaaaac tccttttacc tattatagca aaattatagg gccaaaagga
     6061 gaaatcgctc ttataatttt cgttcaattg atctaaaaat gttttttaat gctttgtcta
     6121 gtgaaagcac ctctgcttcc ctgaccaatc acccctcacc tcacatcgtt ttactttttt
     6181 actcagtaag ctattgacaa tacaaaagac ttgacaccgg taaaaacaaa ggaatcaagt
     6241 cttacatagc tatttatgtc ttaatggttt tttcataggg atagcctaag tgctgatagg
     6301 ctttttcggt gacaactcgg cctgttctgg tacgcatgat aaaacccttt tgaattaaat
     6361 aaggctcgta catgtcttct actgtatctc gctcctctgc tatattgaca gatagagtcc
     6421 caagaccaac cggccctcct tggtacacct caatcatggt acgaagaatc ttttggtcca
     6481 cataatctaa accttcttga tccacatcta acatcgttag agccttatct gtgatttgag
     6541 tcgtaatcat tccatcaccc ataatttgag cataatcacg cacccttttt aacagccgat
     6601 tagcaatacg aggggttcca cgactcctgc gtgccagttc ataagcggcc tcatgcttga
     6661 ttgtcatgtc aaaaatatca gctgtacgct ccacaatctc tgttaaatca gctgtctgat
     6721 aatattccat atgcccagta atcccaaaac gagccctcaa aggatttgac agcatgcctg
     6781 cacgagtcgt tgctccaatt aatgtaaagg gaggcagctc caaatgcaca ctccggctag
     6841 tgtctccagc gccaatcatg atatcaatgt aaaaatcctc catggcactg tacaagattt
     6901 cctcaacagc catcggcata cgatgaattt catcaataaa gaggacatct cctggctcta
     6961 aatcattcaa aattgccacc aaatcaccag ctttttcaat ggctgggcca gaggtctgct
     7021 tgagatgaac tcccaattca ttggcaatga caaaggccat cgttgtttta cccaagcctg
     7081 gggaaccaaa taacaggaca tgatccaagg attcctcacg cctcttggct gcctcaataa
     7141 aaatcatcag ctggtcttta accctatcct gaccaatata ctcacgtaaa tactgtggac
     7201 gtagtgtcct ctcaacagat ccttcatcgc ctatcagatc attatctaaa attcttgtca
     7261 tagagctatt atagcataaa tagatgattt agctttaacc aacacgccac cagtcaatat
     7321 cactaagtaa ttgggcagaa tgaagtagaa ataaagcagc taaaaacaga tagtattggt
     7381 att
//
LOCUS       DARYXW010000094         6885 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.094, whole genome shotgun sequence.
ACCESSION   DARYXW010000094 DARYXW010000000
VERSION     DARYXW010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6885)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6885)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6885
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.094"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(25..486)
                     /locus_tag="TV191_001666"
     CDS             complement(25..486)
                     /locus_tag="TV191_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComE"
                     /protein_id="HEL1508158.1"
                     /translation="MTDRLSWQDYFMANAELISKRSTCDRAFVGAVLVKDNRIIATGY
                     NGGVSATDNCNEAGHYMEEGHCIRTVHAEMNALIQCAKEGISTAGTEIYVTHFPCINC
                     TKALLQAGICKITYKSHYRPHPFAIELMDKKGVAYVQHDVPQIILGGAVEP"
     gene            complement(530..1606)
                     /locus_tag="TV191_001667"
     CDS             complement(530..1606)
                     /locus_tag="TV191_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEL1508159.1"
                     /translation="MSSFLAQRLSNCQALLEKKGLEAILITNLTNIYYLTGFSGTSAT
                     VFISPKRRVFITDSRYTLIAKASIEGFDIIESRTPLAEIAAILQADKLSSLAFEDQVS
                     FSFSQSLQAAFSEVTLLPQSGFIEALRLIKDASEIDIIAKACSISDKAFCDVLDFIKP
                     GQTSELEVANFLDFRMRQYGASGISFDTIAASGYRSAMPHGRATDKIIQQGETLTLDF
                     GCYYQHYVSDMTRTIHIGQVTDQEREIYELVLAANQALIAKAGAGMTYREFDAIPRQL
                     ITEAGYGSHFTHGIGHGIGLDIHEDPFFAKTDQRLLAGMVVTDEPGIYLDGKYGVRIE
                     DDLVITETGCQVLTKAPKELIVLT"
     gene            complement(1897..4719)
                     /gene="uvrA"
                     /locus_tag="TV191_001668"
     CDS             complement(1897..4719)
                     /gene="uvrA"
                     /locus_tag="TV191_001668"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEL1508160.1"
                     /translation="MQDKLIIRGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGLSPAISIDQKTTSKNPRSTVGTV
                     TEINDYLRLLYARVGTPYCINGHGAITASSVEQIVEQVLELPERTRMQILAPLVRRKK
                     GQHKTVFEKIQKDGYVRVRVDGEIFDVSEVPALSKSKMHNIEVVIDRLVNKDGIRSRL
                     FDSIEAALRLGDGYLMIDTMDGNELLFSEYYSCPVCGFTVPELEPRLFSFNAPFGSCP
                     TCDGLGIKLEVDLDLVVPDPSKTLREGALAPWNPISSNYYPTMLEQAMQSFGVDMDKP
                     FEQLSEQEKELILYGSGDQEFHFHYVNDFGGERSIDIPFEGVVTNINRRYHETNSDYT
                     RNVMRGYMNELTCASCHGYRLNDQALCVRVGGEYGLTIGQVSELSIADHLQLLDRLEL
                     SDNESTIAKPIIKEIHDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYVLDEPSIGLHQRDNDRLIDSLKKMRDLGNTLIVVEHDEDTMMQADWLIDVGPGA
                     GDFGGQIVASGTPQQVARHKRSITGQYLSGRKSIPVPLERRAGNGRYIDIKGAAQNNL
                     QNLDVRFPLEKFIAVTGVSGSGKSTLVNSILKKAVAQRLNRNSEKPGKHRSITGIDHL
                     ERLIDIDQSPIGRTPRSNPATYTGVFDDIRELFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVPCDVCHGRRYNSETLEVHYKGKNIAEILDMTVDDALV
                     FFSAIPKIARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSLYIL
                     DEPTTGLHTDDIARLLKVLERFVDDGNTVLVIEHNLDVIKSADHIIDLGPEGGVGGGQ
                     LVATGTPEEVAAVEESYTGQYLKLKL"
     gene            4915..5859
                     /locus_tag="TV191_001669"
     CDS             4915..5859
                     /locus_tag="TV191_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEL1508161.1"
                     /translation="MKQMFLSSAIEFKEIETFEPGAWIKLVNPSQEESIAIADQFNID
                     ISDLRAPLDVEETSRIAVEDDYTLIIVDVPVYEERNNKSYYVTMPLGIIVTESAVITT
                     CLHDMTLFDQFHKRKVKNFYTFMKTRFVFQILYRNAELFLTALRTIDRQSERLEAQLE
                     AATRNEELIDMMELEKSIVYLKASLKFNERIVKKLSSSTSSLKKYIEDEDLLEDTLIE
                     TQQAIEMAGIYENVLNAMTETTASIINNNQNTIMKTLALMTMALDIPTVIFSAYGMNF
                     QDNWLPLNGLSHAFWYIVLLATLLSSFVVIYFIRKKWF"
     gene            complement(5884..6021)
                     /locus_tag="TV191_001670"
     CDS             complement(5884..6021)
                     /locus_tag="TV191_001670"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508162.1"
                     /translation="MAADMLRLIIRSSSSSYRYLLGRLFALAVVVPALADELSTGRAQ
                     E"
     gene            6118..6768
                     /locus_tag="TV191_001671"
     CDS             6118..6768
                     /locus_tag="TV191_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013643410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 family protein"
                     /protein_id="HEL1508163.1"
                     /translation="MDLQQLTKKNQEFIHIATNQLIKDGKTDDDIKALLEEVIPTILE
                     NQKKGITARSLYGAPTAWAASFSKEANQKEATPKNTNPWLMWLDTSLLFIGIVGLLNS
                     IMTFFNTNTTVTGLVSLLALGFGGGASMYATYYFVYRHMGKDKSLRPSWFKVIGALTL
                     AMLAWITLYSATAFLPKALNPQLPPVALLITGALAIGLRYLLQRKYNIQNTMAPQR"
BASE COUNT         1998 a         1792 c         1334 g         1761 t
ORIGIN      
        1 ttatgaccat tatcagcctt cggcctaagg ctcaacagcg ccacccaaga taatctgagg
       61 cacatcatgc tgaacataag caaccccttt tttatccatt agctcaatgg caaaagggtg
      121 gggacgataa tgggatttat aggtgatctt gcaaataccg gcctgaagga gggccttagt
      181 gcaattgata caaggaaagt gcgtgacata aatctctgtt ccagcagttg aaatgccctc
      241 cttagcacat tgaatcaaag cattcatctc tgcatgaaca gttctgatac aatgcccttc
      301 ttccatataa tgaccggctt cattacagtt atcagtcgcc gacacgccac cgttatagcc
      361 tgtcgcaata atgcgattgt ccttgaccaa gactgcaccg acaaatgctc gatcgcaggt
      421 tgatcgctta gatatcagct ctgcatttgc cataaaataa tcttgccatg atagcctatc
      481 tgtcatgctt tgtctcctaa tcccttctaa ctcacagcag ctaacaagcc tacgttaaaa
      541 caatcaattc ctttggtgcc ttggttaaga cctgacagcc tgtttctgtg atgacaagat
      601 cgtcctcaat acgcacaccg tatttgccgt ctaaatagat acccggttca tctgtcacca
      661 ccataccagc tagaagcctt tgatctgtct tagcaaaaaa tggatcctca tgaatatcaa
      721 gtccgatccc atgaccaatg ccatgtgtaa agtgactgcc atatcctgcc tcagtaatga
      781 gctgacgagg aatagcatca aactcacgat aggtcatgcc tgcaccagcc tttgcaatca
      841 aagcctgatt agctgcaaga accagctcat aaatctcacg ctcctggtct gtcacctgtc
      901 cgatatgaat agtccttgtc atatcactca cataatgctg ataataacag ccaaagtcaa
      961 gcgtcaaagt ctctccctgc tgaatgattt tatctgtagc acgaccatga ggcatggcag
     1021 aacgatagcc tgaggctgca atggtgtcaa aggaaatgcc tgaggcaccg tattgacgca
     1081 tgcgaaaatc caagaaatta gccacttcaa gctcacttgt ctgccccggc ttaataaagt
     1141 ccaagacatc acagaaggcc ttgtctgaaa tcgagcaggc tttagcaata atgtcaatct
     1201 cagaagcgtc cttaatcaga cgaagcgctt caataaagcc tgattgcggc agcaaagtca
     1261 cctctgaaaa ggctgcctga aggctttgag aaaaggaaaa ggacacctga tcctcaaagg
     1321 ctagactgct aagcttgtcc gcctgtagga ttgcagcaat ttcagccagc ggtgtgcggc
     1381 tctcaatgat atcaaagccc tcaatactag ccttagcaat taaggtataa cgcgaatctg
     1441 taataaaaac acgccgcttt ggactgataa agaccgtagc tgaggtccct gaaaagcctg
     1501 tcaggtaata aatattagtc agattagtaa ttaaaatagc ctccaagcct tttttttcca
     1561 gtaatgcttg gcaattgctt aagcgctgtg ctaaaaatga tgacatggta atctccttta
     1621 tcgacaaaac taccttaagt ttaccatgat ttcaacgctt ttaaaagcaa gacccattaa
     1681 agacagccaa caaaaaaagc atttctgaca gtggaccaaa aggctaatca gcttagccgc
     1741 cactaccaaa aatacccttt aaatatcacc cacgcccccc gcgaagagag ctactggcta
     1801 tctattattt aaattaaaat cacccctcat ttcaatccat gccctatcat cgttcatacg
     1861 aagatcactc tgtcaattga tgtcaggcct gcaactttac aatttcagct tcaggtactg
     1921 ccctgtgtag ctttcctcaa cagcggcaac ctcttcagga gtcccagttg caaccagttg
     1981 acctccacca acaccgcctt ctggaccaag gtcaataata tggtctgccg acttgatgac
     2041 atctaaattg tgctcaatca ctaaaacagt attaccatca tcaacaaagc gctctaaaac
     2101 cttcagtaat cgcgcaatgt catctgtatg cagccccgtc gttggctcat ctaaaatata
     2161 caagctttta ccagttgaac gcttgtgcaa ttcactagcc agcttcatgc gctgggcctc
     2221 gccacctgat agggttgtcg ctggctgccc tagagtaaca tagccaagcc caacgtcctt
     2281 aatggtctga attttacgag caatctttgg aatagctgag aaaaatacca gagcatcatc
     2341 taccgtcata tccaagattt cagcaatgtt tttgccctta taatggacct ccaacgtctc
     2401 tgaattatag cgtctgccat gacaaacatc acatggaacg taaacatctg gtaaaaaatg
     2461 catctcaatc ttgataatcc catctccaga gcaggcttca cagcggcctc ccttcacatt
     2521 aaaggagaag cgcccttttt tgtagccacg aatcttggct tcattagtct gggcaaagag
     2581 ctctcgaata tcatcaaaaa caccggtata ggtggcagga ttagagcgcg gtgtccgccc
     2641 aattgggctt tgatcaatat caatcaaccg ttccaaatgg tcaatgccag tgatagacct
     2701 atgcttgcct ggcttttcag agttacggtt tagcctttga gccactgctt ttttgagaat
     2761 gctattaacc agcgttgatt ttcctgagcc agagacccca gtcactgcaa taaatttctc
     2821 cagaggaaac ctcacatcaa gattctgcag attgttttgg gctgctccct tgatatcaat
     2881 atagcgacca ttgccagcac gtcgctccaa aggaacgggt attgatttgc gtccagacag
     2941 gtattgacca gtgatagacc ttttatgccg agcaacctgc tgaggcgttc cagaggcaac
     3001 aatctgcccg ccaaagtccc cagcaccagg tcccacatca atcagccaat ctgcctgcat
     3061 catggtatcc tcatcgtgct caaccacaat caaggtattt cccaagtcac gcattttttt
     3121 caagctatca atcaagcgat cgttatctcg ctggtgcaga ccaatagaag gctcgtccaa
     3181 aacgtaaagg acacctgaca gattagagcc aatttgcgtt gccaaacgga tacgctgact
     3241 ctctccacca gacaaggtgc ctgccgagcg agacaaggtc agataattca gaccgacatt
     3301 attcaaaaag gtcagccgat catgaatttc cttgataatt ggctttgcaa tggtgctttc
     3361 attgtctgac agctcaagcc gatctagcag ctgcagatgg tctgcaatag atagctctga
     3421 cacctgaccg atcgtcaagc catactcacc accaacacgc acacacaggg cttgatcatt
     3481 gaggcgatag ccatgacagc tcgcacaggt caattcgttc atatagcctc gcatgacatt
     3541 gcgggtatag tcactgttag tctcatggta gcgacggtta atatttgtca caaccccttc
     3601 aaagggaata tcaatgctgc gctcgccacc aaaatcattg acatagtgaa aatggaactc
     3661 ctgatcacct gagccataca ggatcagctc cttttcctgc tcgctcaatt gctcaaaagg
     3721 cttgtccata tcaacaccaa agctctgcat tgcctgctca agcatggttg ggtaataatt
     3781 tgacgagata ggattccaag gagcaagagc cccctctctc aaggtcttgc tgggatcagg
     3841 aacaactaga tccaaatcca cctccagctt gatccctaag ccatcacagg tagggcaaga
     3901 gccaaagggc gcgttaaatg aaaaaagacg aggctctagc tctggcactg taaaaccaca
     3961 taccggacag gaataatact ctgaaaacag caactcattg ccgtccatcg tatcaatcat
     4021 cagatagcca tctcccaagc gaagcgcagc ctctatcgaa tcaaaaagac gactgcggat
     4081 cccgtcctta ttgaccaagc gatcaatgac gacctctata ttgtgcattt tgcttttgga
     4141 taatgctggt acctctgaca catcaaaaat ctctccatca acacgcacgc gcacataacc
     4201 gtccttttga attttctcaa acactgtctt gtgctgaccc tttttacgac ggacaagagg
     4261 cgccaaaatc tgcatacgcg tccgctcagg caactctagc acctgctcaa caatctgctc
     4321 caccgaggaa gccgtaatag ccccatgccc attgatacaa tagggagtcc ccacacgcgc
     4381 ataaagaagc ctgaggtaat cattgatttc tgtcaccgta ccaacggttg atctaggatt
     4441 cttgctggtt gttttttggt caatagaaat agcaggacta agcccgtcta tagaatccac
     4501 atcaggcttt tccatgttgc ctaaaaattg cctagcatag gctgacaggc tctccacata
     4561 gcgacgttgt ccctcagcat agatggtatc aaaggcaagg ctagattttc cagatcctga
     4621 taagccggtc accacaacga gcttatcacg tggaatctcc acatcaatat tttttaaatt
     4681 gtgggcacgc gccccacgaa taatcaattt atcttgcatg ctcttgtgcc cccaggcacc
     4741 ctcctcatcg agatttattc cattataaca aaaatttcta ataatcagtt gccccaaaca
     4801 ccatgaattt gtagtataat agacaggtat tgagtgtttt tcaaaaaggc ttcgtctacc
     4861 tgatgacaag aagctcactt caatactgac taatcacaaa aaggagggct tgtcatgaaa
     4921 caaatgtttc tttcatcggc aattgaattc aaagaaatcg aaacattcga gccaggtgct
     4981 tggatcaaat tggtcaaccc ctcccaggaa gagtctatcg ccattgccga tcaatttaac
     5041 attgatattt ctgacctgcg tgcccctttg gacgttgaag aaacctcacg tattgctgtt
     5101 gaggacgact acaccttgat tatcgtcgac gttccggtct atgaggagcg caacaacaaa
     5161 agctactatg tgaccatgcc tttgggaatt atcgtcactg aaagcgcggt aatcaccacc
     5221 tgcctgcatg acatgacact ttttgatcag tttcataagc gtaaggttaa aaacttttac
     5281 acctttatga agacacgttt tgtctttcaa attctctacc gcaatgccga gcttttccta
     5341 accgcactaa gaacaattga ccgacaaagc gaacgcttgg aggctcagct tgaggcagca
     5401 acccgaaacg aagaattaat cgacatgatg gagcttgaaa aatccatcgt ctacctaaag
     5461 gcctccctaa agttcaacga gcgcattgtc aaaaaattat ccagctcaac cagctcactc
     5521 aaaaaatata ttgaggacga ggacctgctt gaggatacac tgattgagac ccaacaggct
     5581 attgagatgg ctggcattta tgaaaatgtc ttaaatgcca tgaccgaaac aaccgcctca
     5641 atcattaaca acaatcagaa caccatcatg aaaacattgg ctctgatgac gatggctcta
     5701 gatattccga cagtgatctt ctcagcctac ggcatgaact ttcaggataa ttggctgccg
     5761 ctcaatggcc ttagccatgc cttctggtat attgtcctgc tggcaaccct gctcagcagc
     5821 tttgttgtta tttattttat tagaaaaaaa tggttttaat aaccccattt ccaactgaaa
     5881 aagctactcc tgagctctac ctgtagacag ctcatcagct aaagcaggca ctactactgc
     5941 taaagcaaac aatcgtccca gcaagtaacg gtagctacta ctgcttgatc gtatgatcaa
     6001 gcgcaacata tcagctgcca tactagctgg caaagcaagc cagcaaggcg cccttgaggc
     6061 attatcccag gctagccctg cttacaatca tcacatcata taggagaatc ccctgtcatg
     6121 gacttacaac agcttaccaa aaaaaatcaa gaatttattc atatcgccac caatcagctc
     6181 atcaaagatg gcaaaactga tgacgacatc aaggcacttc ttgaggaggt cattccgacc
     6241 atcttagaga accagaaaaa aggcatcact gcaagaagcc tatacggggc tccaactgcc
     6301 tgggcagctt cctttagtaa agaagcaaat caaaaagaag ccacacccaa aaacaccaat
     6361 ccatggctga tgtggcttga tacctcgctt ctatttatcg gtattgttgg ccttttaaac
     6421 agtatcatga ccttctttaa taccaacact accgttaccg ggcttgtgtc cttgcttgct
     6481 cttggctttg gagggggtgc ttccatgtac gccacctact attttgttta tcgccatatg
     6541 ggcaaggaca agagccttcg tccaagctgg tttaaggtta ttggtgctct gacacttgca
     6601 atgctggcct ggataaccct ctattctgct acagcctttt taccaaaggc gctcaaccca
     6661 caattacctc ctgtagcact tctcattacc ggtgccttag ctatcggact gcgttacctc
     6721 ttgcagcgca aatacaatat ccaaaacact atggcaccgc agcgctagca gcagctccac
     6781 tgcctgagga agcacttccc tattctctct tgagggcagt tagccttttc ataccatatt
     6841 gctggcaaca ccagacactg atctacaatc gacactcctc aatcc
//
LOCUS       DARYXW010000095         6878 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.095, whole genome shotgun sequence.
ACCESSION   DARYXW010000095 DARYXW010000000
VERSION     DARYXW010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6878)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6878)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6878
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.095"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(46..363)
                     /locus_tag="TV191_001672"
     CDS             complement(46..363)
                     /locus_tag="TV191_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508164.1"
                     /translation="MADRIVEEVAIYRKLREMDDAEQDFLRQKRAYQKREDSLSERRH
                     VLNDLINSEYQKMSVFLKRLDLSANAASDFFNELGRLKDQSNAEFHLFLKLGKILNNK
                     SLG"
     gene            complement(345..1634)
                     /locus_tag="TV191_001673"
     CDS             complement(345..1634)
                     /locus_tag="TV191_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508165.1"
                     /translation="MAISDSSYNELAKQVYNVEPSKAKSNGDLVIVAGKTVKDPITKR
                     QYRVLLVQDNNNDAHKTNDNGMQAMAVAPIVKGDIDTSQVVIAYAGTNAADSRDLDTD
                     WQLLIRGNQDDLVSGNIDGGNFVIAENQLRSAQKFYQQVKRKYPHSALTTTGHSLGAY
                     LALIVAAEHKIPATTFNGPDPVRGMSAEAITWVKANSNMYNNFRINFDGIGNFGAYFG
                     TDDLAISRNVDAMLLSANPLYYHDLGAYRFNQKGQIVDRDGKLIGTQYLVSRAYLTVL
                     ASKKSMSSYNQLKKHWQSTGKGISSSEELFLDAAQGMILGSSMAKAAREGADEALDHK
                     TVADAKLMEVWSAIDFNSFHELPYYEVQALFASYGITYDRFVQDFQDYTQSKVSKLSA
                     LATDFENLNRDIQTVIDSKLETDRQLAGEFRAWQTEL"
     gene            complement(1636..2079)
                     /locus_tag="TV191_001674"
     CDS             complement(1636..2079)
                     /locus_tag="TV191_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508166.1"
                     /translation="MMTVKTNKQRLWLGLIIVIGAIIMVFRLNGKRTEEQQKRDLETS
                     IAKLLVHDYEGVKEVKFTGWGHSRETGSWGTIVIINGENEIGFSFDGLSSLEKIRGIV
                     TDDDTEKMEKPETDTKPRIMDRIDKINKTSLVGVTVIYSKDNQED"
     gene            complement(2444..5995)
                     /gene="smc"
                     /locus_tag="TV191_001675"
     CDS             complement(2444..5995)
                     /gene="smc"
                     /locus_tag="TV191_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEL1508167.1"
                     /translation="MFLKEIQMQGFKSFADKTKIIFDKGVTAVVGPNGSGKSNVTESL
                     RWALGEASAKSLRGGKMPDVIFAGTEHRSPLNYAEVAVVLDNSDAFIKNAQKEIRVER
                     HIYRNGDSDYLIDGKKVRLRDIHELFMDTGLGRDSFSIISQGRVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRKKETQTKLNQTQDNLDRLDDIIYELEHQAGPLERQAKTARQFLAL
                     DADRKQLQLDILVKDIEQDRMEQEAQEKALVALREDLAAYHRKRQSLEAENHRLKTKR
                     QKLSAVAEQTQADLLELTKVISDLERQIDLIKLDLSQKQEKKTEASQRRQQAQEQLLA
                     FQQEHQQKSRQLDEIHQALAEFNTKVSELSQELERFSSDPDQLLEALREDFVGLLQQE
                     ADVSNQLTAIVAQLDKESQAKASQAQEYQVLQEKVNQLSQDTQTALLAYQASQSRLEQ
                     LLADYQELAKTVEALEQDYHQGQTRLFDLLDQKKAKEARRASLVSIQKNHSQFYAGVR
                     AVLQAAGKLDGILGAVSEHLTFDSQYQTALEIALGASSQHIIVADEAAAKRAIAFLKA
                     NRQGRATFLPLTTIKARQLSEVTLKQLRACQGYLGTADSLVTYEPSLVAIVQSLLGVT
                     AIFDTIDHANQAAKQLHYKVRIVTLDGTELRPGGAFSGGTNRHNSTTFIKPELEQIEK
                     ELALLSEQIKESEKAVAAVQADLKAKKAAQADTKLAGEQARLVEQKTQLAYQQLAEKL
                     ADSKELLELLSNRQTGQSSERLLSEKARLEEALQLLADEKSALTSEIEQIKENKDTIK
                     QKKDQLSQELSQARLKERDLLNEKKFEAANQRRLETMIAQGQKELANLETVLSHQVSQ
                     EAIDQLPHLENQLTEANQDKIKTQERFIQLRFEGEDYDARLEELEAQLLKEAKKNEAF
                     IRQQARLEADLEQVIGRLRQHARSLSEELQLSLEEAKEQASPINDTDMAAARQKLQQV
                     QQSIRALGPINSDAIAQFDEVSERLAFLNGQRADLIKAKNLLVDTIGNMDHEVKARFR
                     VTFEAIRDSFKETFRQMFGGGSADLMLTETDLLSAGVDISVQPPGKKLQSLNVMSGGE
                     KALSALALLFAIIRIKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRK
                     GTMAAADSIYGITMQESGVSKVVSVKLKDTQDLTYLS"
     gene            complement(5996..6688)
                     /locus_tag="TV191_001676"
     CDS             complement(5996..6688)
                     /locus_tag="TV191_001676"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEL1508168.1"
                     /translation="MKKLEALLENSFNIRFDDKRLLETAFTHTSYANEHRLLNISHNE
                     RLEFLGDAVLQLIISEYLFAKYPKQTEGDMSKLRSTIVREESLAGFSRYCSFDAYIKL
                     GRGEEKSGGRHRDTILGDLFEAFLGALLLDKGIEEVRRFLNQVMIPQVEQGTFEKVKD
                     YKTCLQELLQAKGDVVIDYQVISETGPAHAKQFEVAVLVGEDHLSKGTGRSKKLAEQD
                     AAKNALAQLSEV"
BASE COUNT         1831 a         1713 c         1275 g         2059 t
ORIGIN      
        1 tacaagatgc taaattgcaa gtaaaagtta gtcatcctat agaaattatc cgagtgactt
       61 gttgttcaaa attttcccca attttaaaaa gagatgaaac tctgcgttgg attgatcctt
      121 taagcgaccc aattcattga aaaaatctga tgcagcattg gcagataggt ctaaacgctt
      181 caaaaaaaca ctcatcttct ggtactcaga gttgatcaaa tcatttaaga catgtcttct
      241 ttcagataag ctgtcttcac gcttctgata ggctcttttc tggcgtagaa agtcctgctc
      301 ggcatcatcc atctcccgaa gcttacgata aatagccact tcctctacaa ttctgtctgc
      361 catgctctaa actctcctgc taactgacga tccgtttcaa gcttgctatc aataaccgtc
      421 tgaatatctc tattcaagtt ttcaaagtct gtggccaagg ctgacagctt gctgaccttg
      481 gattgagtat agtcctgaaa gtcttggaca aagcggtcat atgtgatacc ataagaagca
      541 aataaggcct gcacctcata gtagggcagc tcatgaaaag agttgaagtc aatcgccgac
      601 cacacttcca taagctttgc gtctgcaacc gttttatgat ccagagcttc atcagccccc
      661 tctcgagcag ccttagccat ggacgagcct aggatcattc cctgtgccgc atctaaaaag
      721 agctcctcag aactactgat ccccttgccg gtagactgcc agtgtttttt gagctgattg
      781 tagcttgaca tgctcttttt tgaggcaagg acagttaaat aggcccgact cacaaggtat
      841 tgtgttccaa tgagcttacc gtctctatct acaatctgac ccttttgatt aaaacgataa
      901 gctcctaaat cgtgataata caaggggttg gctgataaga gcatagcatc gacattccga
      961 gaaatagcta aatcatcagt tccaaaatag gcaccaaaat tgccaatgcc atcaaaatta
     1021 atgcggaaat tattgtacat attgctatta gccttaaccc atgtgatagc ttcagctgac
     1081 atgccgcgaa cagggtctgg accattaaag gttgttgctg ggatcttatg ttctgcggca
     1141 actattagtg ctagataagc tccgagagag tgacctgtgg ttgttaaggc agaatgaggg
     1201 tactttcttt tgacctgttg ataaaacttt tgagcagatc gtaattggtt ttcggcaata
     1261 acaaaattgc caccatcaat attgccgctg actaaatcat cttgattgcc ccgaatgagc
     1321 agctgccaat ccgtatcaag atctctggaa tccgcagcat ttgtccctgc ataggcaatc
     1381 acaacctgag aggtatcgat atcaccttta acaatagggg ctacagccat tgcctgcata
     1441 ccgttgtcat tggttttatg ggcatcgttg ttattgtcct gaactaagag gactcggtat
     1501 tgtcgtttag tgataggatc ttttacagtt ttaccagcaa caataacaag gtctccattt
     1561 gatttagctt tgctaggttc gacattataa acctgtttag ccaactcatt ataactacta
     1621 tccgatatcg ccatattaat cctcctgatt gtcctttgaa taaatgacag taacacctac
     1681 aagagatgtt ttattaatct tgtcaatcct atccataatt cttggtttgg tatcagtttc
     1741 aggcttttcc atcttttctg tatcatcatc agtaacaatt cctcgtattt tctcaagact
     1801 agacaagcca tcaaacgaaa agcctatttc attttctcca tttataatca ctatcgttcc
     1861 ccacgaacct gtttcccgag aatgtcccca gcctgtaaac ttaacttctt taaccccttc
     1921 atagtcatga accagcagct tagcaatact ggtttccaag tccctttttt gttgttcctc
     1981 tgttcttttg ccattcaaac gaaaaaccat tatgatcgct cctattacta ttattaagcc
     2041 tagccatagc ctttgcttat tggtcttaac tgtcatcatg tcctcctttc actcttttgc
     2101 tatgcgtccg tcactctaag gaaggcagca tgactaatta gggtgaaatc aacgccaaat
     2161 cttatttata ttattctcat tttgtaatta aattataata tacagacatc tacttgtcaa
     2221 tatattatgt ccttagttac ttttttggta tattttaatc aaaacaagcc gtactaagtt
     2281 ccaggagcat gtcaaaaaca gcagcttact gctagccaat ccttgtgctt tgtcctttgg
     2341 aaagccaaaa aacctaccat gacgataggt ttttttatag cttattcttg gttatcatct
     2401 gctacatgta gaaatacagc taaaactaag ctctgtccta gagttatgac aagtaagtca
     2461 gatcctgcgt atccttgagc ttaacagata ctaccttaga aacaccagat tcttgcatgg
     2521 taatcccata aatactgtct gctgctgcca ttgtcccctt gcggtgggta accacgataa
     2581 actgactatc cttgtcaaaa cgattgagat aatctccaaa acgcttgaca ttggcctcat
     2641 caagggccgc ctcaacctca tctaaaatca caaagggaat ggtcttaatg cggataatag
     2701 caaataaaag ggctagcgct gataaggctt tttctccgcc agacatcaca ttcaaagatt
     2761 gaagcttttt accaggcggt tgcactgaaa tatctactcc agcagaaagc agatcagtct
     2821 ctgtcaacat caagtccgct gagcccccgc caaacatctg cctaaaggtc tccttaaagc
     2881 tatcacgaat agcctcaaag gtaaccctaa agcgtgcctt aacctcatgg tccatattgc
     2941 caatcgtatc taccaagaga ttcttggcct tgataaggtc agccctttga ccatttaaga
     3001 aggccaaacg ctcactaacc tcatcaaatt gagcaatagc atcactattg attgggccta
     3061 gggcacgaat gctttgctga acctgctgca atttctgtct tgctgctgcc atgtcagtgt
     3121 cattgattgg gcttgcctgc tccttggcct cctctaagct tagctgaagc tcctctgata
     3181 ggcttctagc gtgctgccgc aaacgaccaa taacctgctc taagtcagcc tccagtcttg
     3241 cctgctgacg aatgaacgct tcatttttct tggcttcctt aagcaattga gcctctagct
     3301 cctccagtct ggcgtcatag tcctcacctt caaagcgcag ctgaatgaag cgctcctgag
     3361 tcttgatctt gtcttgatta gcctctgtca gctgattttc taggtgaggc aattggtcaa
     3421 tggcctcctg actaacctga tgtgataaaa cagtctccaa attagctaat tccttctgac
     3481 cctgagcaat catcgtctcc aagcgacgct ggttagctgc ttcaaacttt ttctcgttga
     3541 gcaaatctcg ctctttaaga cgagcctgag ataattcctg gctaagctgg tccttctttt
     3601 gcttaatcgt atctttattt tccttaattt gctcaatttc tgacgttaag gctgattttt
     3661 catcagctag gagctgcaat gcctcctcca gcctcgcttt ttctgataat aagcgctcac
     3721 tagactgacc agtctgacgg ttgctgagaa gctctagcag ctcttttgag tcagccagct
     3781 tttctgctag ctgctgatag gccaattgtg ttttttgctc gaccagtctt gcttgctcac
     3841 cagccagctt agtatcagcc tgcgcagcct ttttagcctt caaatcagcc tgtacagcag
     3901 ctactgcttt ttcagattcc ttgatctgct cagaaagcaa ggctaattcc ttctcaatct
     3961 gctctagctc tggcttgata aaggttgtgc tattgtgacg attagtcccc cctgaaaagg
     4021 caccaccggg acgcagctcg gtaccatcaa gcgttacaat cctgacctta taatgcagct
     4081 gcttagctgc ctgattagca tgatcaatgg tatcaaaaat agccgtcaca cctaacaggc
     4141 tttgtacaat agcgaccaaa gagggctcat aggtcaccaa agaatcagct gtgcctaaat
     4201 agccctgaca agccctgagc tgcttgagag tcacctcaga aagctgacgg gccttaatcg
     4261 ttgtcagagg taaaaaggtc gcacgcccct gacgattagc ctttaaaaag gctatcgctc
     4321 gcttggctgc tgcctcatct gccacgataa tatgctgact actagctccc aaagcaatct
     4381 caagtgccgt ttgatactga ctatcaaagg tcaaatgctc actaactgct cctaaaatac
     4441 catctagctt accagcagcc tgaagcactg ccctaacacc tgcgtaaaat tgactatgat
     4501 ttttttggat agaaaccaaa ctagccctac gagcctcctt ggcttttttc tgatccaaca
     4561 aatcaaaaag ccttgtctgt ccctgatgat aatcctgctc caaggcctca actgtctttg
     4621 ctagctcttg ataatcagct aggagctgct caagtcttga ttgactagct tgataagcca
     4681 aaagagcagt ctgggtgtcc tgactgagct gattgacctt ctcttgtagg acttggtatt
     4741 cctgcgcctg actggctttc gcctgacttt ccttatccag ctgcgctaca atagcggtta
     4801 attggtttga cacatcagcc tcttgctgga gcagaccaac aaaatcctca cgaagagcct
     4861 caagcagctg atctggatcg ctagaaaatc gctcaagctc ctgagaaagc tcgctgacct
     4921 tggtattaaa ctcagctaag gcttgatgga tttcatctag ctgacgactc ttttgctgat
     4981 gctcctgttg aaaggcaagc aattgctcct gagcctgctg cctgcgctga ctggcttctg
     5041 ttttcttttc ctgcttttga ctaaggtcca gcttgatgag gtcaatctgt cgctccagat
     5101 ctgatatgac ctttgtcaat tctagcaaat cagcctgcgt ctgctcagct acagcagaga
     5161 gcttttgccg cttggttttt agacggtgat tttccgcctc tagactctga cgcttcctat
     5221 gataggccgc tagatcctca cgaagagcta ctaaggcctt ttcttgagcc tcctgctcca
     5281 tgcggtcttg ctctatatcc ttgaccaaaa tatccagctg cagctgctta cgatcagcat
     5341 ctaaggctaa aaattgccta gcagttttcg cctgtctttc tagaggacca gcttgatgct
     5401 caagctcata gataatatcg tctaagcggt caagattatc ttgagtttgg tttagcttag
     5461 tttgcgtctc cttcttgcgg gtcttgtatt tcaaaactcc agctgcctct tcaaagatgg
     5521 cccgtctttc ctctggctta ctattgaaaa tctcctcaac acgaccttga gaaataatag
     5581 agaacgaatc gcgccctagt cctgtatcca taaacagctc gtgaatatct cttagcctaa
     5641 cttttttgcc atcaatcaga taatcactgt cgccattgcg atagatatgc ctctccacac
     5701 gaatctcttt ctgagcattc ttaataaagg catctgaatt atccaagaca acagccacct
     5761 ctgcataatt caagggactc cgatgctcag ttccagcaaa gatcacatct ggcatcttgc
     5821 caccgcgcag gcttttggca ctggcctcac caagtgccca acgaaggctt tctgtcacat
     5881 tactttttcc agagccattt ggccctacaa cagctgtgac ccccttatca aagataatct
     5941 tggtcttatc tgcaaaagac ttaaagccct gcatttgtat ttcttttaaa aacatttaga
     6001 cctcactaag ttgggccagg gcatttttag cagcgtcctg ctctgccagt tttttagatc
     6061 tacctgtccc cttgctaaga tgatcctcac caaccaatac agctacctca aattgcttag
     6121 catgagctgg tccagtctcg ctaatcacct gataatcaat cacaacatca cccttagcct
     6181 gtaacaactc ctgcaagcag gttttataat ccttgacctt ctcaaaagtt ccctgctcaa
     6241 cctgtggaat cataacctga tttaaaaagc gacgaacctc ttcaatgcct ttatccaaaa
     6301 gaagagcacc caaaaaagcc tcgaacaaat cgcctaaaat cgtatcacga tgacggcctc
     6361 ctgatttttc ctcgcccctg ccaagcttaa tataagcatc aaacgaacaa tagcgtgaaa
     6421 agcctgctaa gctttcctct ctgacaatcg ttgatctgag ttttgacata tcaccctcag
     6481 tctgcttagg atacttggca aagaggtatt ctgaaataat taactgtaga acggcgtctc
     6541 ctaaaaattc caaacgctca ttatgtgaaa tgtttaggag gcgatgctca ttagcataag
     6601 aggtatgtgt aaaggcagtc tctagtaatc ttttatcatc aaaacggata ttaaaagagt
     6661 tttccagcag ggcctcaagc tttttcatca tgacaaatct ccttttctaa tgtccttata
     6721 aaccattcta ttataacaaa aatccacttg aaaggcttat cacaagtgga tttttcagaa
     6781 atattgtacc aaataggcac gagctattga ctgctgctat ttcccgactt tatcacttgt
     6841 tttagtccac accttactca acctcttggt agagtaag
//
LOCUS       DARYXW010000096         6810 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.096, whole genome shotgun sequence.
ACCESSION   DARYXW010000096 DARYXW010000000
VERSION     DARYXW010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6810)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6810)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6810
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.096"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(7..369)
                     /locus_tag="TV191_001677"
     CDS             complement(7..369)
                     /locus_tag="TV191_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEL1508169.1"
                     /translation="MHFKRRVKAGVLLYALLMASVFLLLLQAYLSHISQLHQEYQAQM
                     DYAKAQLIAEMVYQEQPSGDGQIAFNCGQVSYKSHKQRFIIEIKLPHQQLYQFSYPEV
                     QQASQTSKKQSELKQSLP"
     gene            complement(347..781)
                     /locus_tag="TV191_001678"
     CDS             complement(347..781)
                     /locus_tag="TV191_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEL1508170.1"
                     /translation="MKDSRLKAFTLIECLIALLVISGSLLVYQALTKSLMANERYLAA
                     NDQNNWLLFSQQLRAELSGTTLQGVRNNRLYVEKDKKALSFGQVKGHDFRKAASNGQG
                     YQPMLFGLSSSQITAVGQQVTIKLKWQSGLERTFIYAFQEKG"
     gene            complement(768..1058)
                     /locus_tag="TV191_001679"
     CDS             complement(768..1058)
                     /locus_tag="TV191_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEL1508171.1"
                     /translation="MVIIKKQVKAYIALEGLIATGLILVIVTLILSALRYSQQELSAC
                     RQKQELLNTAVMAMQTKQRALSLNGCHIKLLSHQKGIAIVEKDQTIIRIERQ"
     gene            complement(1015..1440)
                     /locus_tag="TV191_001680"
     CDS             complement(1015..1440)
                     /locus_tag="TV191_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEL1508172.1"
                     /translation="MKLRSSIKAFTLLEGLLTLFLISFMLLYLSLPVSDSYARVEEHL
                     FFMRFEQAYRHLQKLSILRQKEHVLVLKPHYIKAEEAILPLPKQVKLKSTQTLTIDKL
                     GGNHSLARVVFENRDRQITYQFYLGSGNYQKTSQSLHRS"
     gene            complement(1418..1741)
                     /locus_tag="TV191_001681"
     CDS             complement(1418..1741)
                     /locus_tag="TV191_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEL1508173.1"
                     /translation="MKMRLSILKDQGVQAFTLLEMLLVLLIISVLMLLFVPNLSKQKD
                     KVTDTGNAAVVKLVENQAELYELSHGEKPSLKQLQEDGSISDKQQKAYQDYYAKHKDE
                     AKKLN"
     gene            complement(1742..2728)
                     /locus_tag="TV191_001682"
     CDS             complement(1742..2728)
                     /locus_tag="TV191_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEL1508174.1"
                     /translation="MKKLSSKQQEKLIQLLYNLLSNGFNLTEVIAFLRKSQLLLPVYV
                     TSMEASLLKGNGLADMLAALGYSDAVMTQINLADKHGNIKLTLEKIQDYLSQFRQIKR
                     KTIEAVTYPIILLGFLVVIMLGLRHYLIPQLESQNTLTDLLLHLPHYFLGFCLLVLLL
                     IGSFYLYAKSCSRLKLFSQLSYYPIIGSLLRQYLTAYYAREWGNLIGQGLELITILEM
                     MSNEKSQLMRELAKDIKQSLLAGQSFHQRVAAYPFFKKELSLMIEYGDIKSKLGQELD
                     IYSQESWETFFSQLNRATQWIQPIIFLVVAVVIVMIYAAILLPIYQQMGDVF"
     gene            complement(2709..3647)
                     /gene="tadA"
                     /locus_tag="TV191_001683"
     CDS             complement(2709..3647)
                     /gene="tadA"
                     /locus_tag="TV191_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HEL1508175.1"
                     /translation="MIQELAKRLIRQAEELQAQDIYILPRGTGYELLMRVGDDRRLID
                     VCESDRMANLISHFKFVAGMNVGEKRRCQLGACDYDLDDTKVSLRLSAVGDYQGQESL
                     VIRLLYHHQRQLRYWFDGLERVTSAIGARGLYLFSGPVGSGKTTLMYQLVSDYCKELQ
                     VISIEDPVEIKNDQLLQLQVNDSIGMTYDNLIKLSLRHRPDVLIIGEIRDTQTARAVI
                     RASLTGAMVFSTVHAKSISGVYARLLELGISRAELDNSLAMVAYQRFISGGALIDCAQ
                     KEFEHHQANRWNQQIDQLLAEGHLNTRQARLEKIIQ"
     gene            complement(3829..4476)
                     /locus_tag="TV191_001684"
     CDS             complement(3829..4476)
                     /locus_tag="TV191_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1508176.1"
                     /translation="MIRLEKVSKCFGDRVLFSDLSMTFESGKVYALIGSSGSGKTTLM
                     NMLAALEDYQGEIFFRGKNLKTYRSSDFFRHELGYLFQHFGLLESQTIADNLKLGLIG
                     QKISKEEGRQRELEALRAVGLDYLSLEKPVFELSGGEYQRVALAKVMLKDPPFILADE
                     PTASIDPEASKAIMAILLSLRHKNRTIIIATHSPSIWEMADEVISVDQLSSLTRL"
     gene            complement(4478..6481)
                     /locus_tag="TV191_001685"
     CDS             complement(4478..6481)
                     /locus_tag="TV191_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEL1508177.1"
                     /translation="MKRLFIILSNILVSLFLVWVFTIWSDTFVSHYYPSVVVLDASPK
                     ASYNQVEAGLTRLADETDSLIAMQHQEPGPEGTPIVTYTLFGKGKLPGGLAEKVIEEP
                     SRLSVENNYFILKGGLTVERLRDTLAGLGMTKMTALKPSFLGTLVLIFSSGSQALGIV
                     IFCLTFGALTLIGHIRTLRAVGIRLISGERRWQIFLYPIRSDVCYCCLGLLLGLSLAA
                     IMSQLMSFSPLVLYLIGIGLVCYNLLLIAIALFFAGLFVIGIKRVHLMQVIKGQIPVR
                     GIISLILIAQLLAVLVVSFGASRTLLYVQAERQQKQGQAAWLQEDRLVTLLIGRDGLD
                     IGNTKEAIAKQKTWFHVMDQAVSEHGAILSRHYLVERDLQSGLSMLTASSSWNDYSPQ
                     GNVLLVTPQYVKHQKVEVAPDISEKINQLSLGEFVLLLPEHLKTQAAQYQSVFESAVT
                     GLASGEGHQPMTATVSYTKTGQERFLYNTTPISYQQFLRDPIIVVLTPKSTGEQAYAF
                     WEVALQNYFLFDQLADTQTLIKQNGIENWVGELKTGYRIYETLLNNLRREIWLMIAGA
                     ILGIATSMLMFNTMNLLYFEEFRRDIFIKRVSGLRFFELHRRYLLSQLLVFFVGLVIS
                     ALLTQNPLMCLLVFFLFLGNAILLLYRQMRIENKMSLLILKGA"
BASE COUNT         2084 a         1593 c         1266 g         1867 t
ORIGIN      
        1 ccttagttat gggagtgatt gcttaagctc agactgcttt ttagaagtct gagaggcctg
       61 ctgaacttca ggatagctaa attgatatag ctgctgatgt ggtaatttga tctcaattat
      121 aaaacgctgc ttatgcgact tatagctaac ctgaccacaa ttaaaggcaa tctgaccatc
      181 gccagaaggc tgctcctgat aaaccatttc tgctattagc tgagcctttg cgtagtccat
      241 ctgagcctga tattcctgat gtagctggct aatatgacta agataagcct gtaacagtaa
      301 taaaaagacc gatgccatca gcaaagcata caaaagcact cctgccttaa cccttctctt
      361 gaaatgcata aataaaggtc ctttctaagc cgctttgcca tttcagcttg atggtcacct
      421 gctgacctac tgctgttatt tggctacttg acaagccaaa cagcatgggc tgatagcctt
      481 gaccattgct agctgctttt ctaaaatcat ggcccttgac ctgtccaaag gacaaagcct
      541 tcttgtcctt ttcaacatat agcctattat tgcggacacc ctgtagggta gtacctgaaa
      601 gctctgctcg caattgctgg gaaaacaaaa gccagttgtt ctgatcattt gctgctagat
      661 acctctcatt tgccataagg ctcttggtta aggcctgata aactaataaa gagcctgaga
      721 tgacaagcaa ggcaataagg cactctatca aggtgaaagc ctttagccta ctgtctttca
      781 atcctaataa tcgtttggtc tttttcaaca atagcgatac ccttctgatg tgataatagc
      841 ttaatatgac aaccattaag gcttaatgcc ctttgttttg tctgcatagc catcacagct
      901 gtattcaaca gctcttgctt ttggcgacag gccgacagct cctgttggct ataacgcagg
      961 gctgacagta tcagtgttac aataacaaga ataagtcctg tcgctatcaa gccttcaaga
     1021 gcgatgtagg ctttgacttg ttttttgata attaccactc cctaaataaa attgataagt
     1081 aatctgccga tctctatttt caaagacaac tcttgccagc gaatggttgc cgcccagttt
     1141 atcaatggtt aaggtctggg tagattttag cttgacctgc tttggtagag gcaaaatagc
     1201 ttcttcggcc ttaatataat gtggctttaa gaccagcaca tgctcttttt gacgtaatat
     1261 cgatagcttc tgtaggtgcc tataagcctg ttcaaagcgc atgaaaaaga gatgctcctc
     1321 aaccctagca tagctatctg ataccggtag tgacaagtac agcagcataa agctaatcag
     1381 aaaaagtgtc agtaaaccct ctaagagggt aaaagcttta attgagcttc ttagcttcat
     1441 ctttatgctt tgcataataa tcctgataag ccttttgctg cttgtcactg atacttccat
     1501 cctcttgcag ctgcttcagg cttggctttt ccccatgtga taattcataa agctctgcct
     1561 gattttcaac cagctttacc accgcagcat tgcctgtgtc tgtcacctta tccttttgtt
     1621 tacttaaatt tggaacaaat aacagcatca aaacactaat gattaacaaa accagaagca
     1681 tttccagtaa agtgaaggcc tgaacacctt gatcttttaa gattgataat ctcattttca
     1741 tttaaaaaac atctcccatc tgttgataaa ttggtaataa aatagcagca taaatcatca
     1801 caataaccac agcaaccact aaaaaaataa tcggctggat ccattgtgtt gcccgattaa
     1861 gctgactaaa aaaggtctcc cagctttctt gggaatagat atctaattcc tgaccaagct
     1921 ttgatttgat gtcaccatat tcaatcatta ggcttagctc ctttttaaaa aagggataag
     1981 ctgcaaccct ttgatgaaag gattggccag ctagtagact ctgcttgata tccttggcaa
     2041 gctctcgcat gagctgtgac ttttcgtttg acatcatctc taaaatggtg attaattcta
     2101 agccttgtcc gatgaggttg ccccattctc tagcatagta ggctgtcaaa tattgccgca
     2161 ataaggaccc aatgatagga taatagctca gctgactaaa tagttttagc cgactacagg
     2221 acttggcata taggtaaaaa gagccaatta gcaacagcac aagcaaacaa aaacctaaga
     2281 aataatgagg caaatgaagc aacaagtcag tcaaggtatt ttgactctct agctgaggga
     2341 ttaggtaatg acgcaagcct agcatgataa ccactagaaa acccaaaagt ataatcggat
     2401 aagtgactgc ctcgatggtc tttcgcttga tttggcgaaa ttgactcaga tagtcctgaa
     2461 ttttttccaa ggttagcttg atattgccat gcttatctgc cagattaatt tgtgtcataa
     2521 cagcatcaga gtaacctaag gctgctagca tgtcagcaag gccgttgccc tttaataggc
     2581 ttgcttccat acttgtaaca tagactggca gtagcagctg gctttttctc aaaaaagcaa
     2641 tgacctctgt caaattaaag ccgttagaca ataggttata gagcaattgg ataagctttt
     2701 cctgctgctt actggataat tttttcaagc cttgcctgcc tggtattgag atgtccctcc
     2761 gcaagaagct gatcaatctg ctgattccac cggttggctt gatgatgttc aaattccttt
     2821 tgtgcacaat caattaaagc acctccacta ataaatcgct ggtaagcaac cattgctaga
     2881 ctattatcca attctgccct agaaatgcct aattctagca gtctagcgta aacgcctgaa
     2941 atactctttg catggacggt tgaaaagacc attgctcctg ttaggctagc cctaataacc
     3001 gctctagcag tctgtgtatc tctaatttct ccgataatca acacatctgg acgatgacgc
     3061 aaggaaagct taatcagatt atcgtatgtc atgccaatgc tatcgttaac ctgtaattgc
     3121 aggagctggt cattttttat ttccacagga tcctcaatac tgatcacctg aagctccttg
     3181 caatagtcag agactagctg atacatcagg gttgtcttac ctgatcccac cggtccagaa
     3241 aagaggtaaa ggcctctagc tccaatagct gatgtgactc gctctaaacc atcaaaccaa
     3301 tacctgagct ggcgttgatg atgatacaag agacgaataa ccaagctctc ctgtccctga
     3361 taatcaccca cagctgataa tcgtagagac accttagtgt catcaaggtc gtagtcacaa
     3421 gcaccgagct gacagcgtct tttttcgccc acattcattc ctgcaacgaa cttaaagtga
     3481 ctaataagat tagccatccg atcactttca caaacatcta ttagcctcct atcatcacct
     3541 accctcatca aaagctcata gcctgtcccc cttggtagta tataaatatc ctgagcctgc
     3601 aattcttcag cctgcctgat aagccgcttg gctaattctt gaatcattct tacctcctca
     3661 ctaagactat tcgaaaaata aaaaaaatag cctcaagaaa aaggccattt tttgataaat
     3721 gtttaacatc aagtaaggaa ttcagcacgc tacaaacagc gcagaatcct tttgcgatgc
     3781 tatgatgaca aggtcaagcc ttaatcactt agctagtcca ggctttattt agagcctggt
     3841 gaggctgcta agctgatcaa cagagatgac ctcatctgcc atttcccaaa tgcttgggct
     3901 gtgggttgcg atgataattg tccgattttt atgccgaagt gacagcaaaa tagccataat
     3961 tgccttagaa gcctctggat caatagaagc cgtaggctca tcagctaaaa taaagggagg
     4021 atcttttagc atcaccttag ctagggcaac acgctggtat tcaccaccag acaattcaaa
     4081 aacaggcttt tctaagctca gataatccaa gccaactgcc cttagggctt ctaattccct
     4141 ttgccggcct tcctccttgc ttattttttg accaattagc cctagcttca aattatcagc
     4201 aatcgtctga ctctccaaca gcccaaaatg ctgaaatagg tagcccaatt cgtgacggaa
     4261 aaaatcgctg gatctgtatg ttttcaagtt ttttccacga aagaaaatct caccctgata
     4321 atcctcaaga gctgccagca tattcatcaa ggttgtctta ccactaccgc ttgacccaat
     4381 cagggcataa acctttccag actcaaaggt cattgacaaa tcagaaaata agacacgatc
     4441 accaaagcat ttactaacct tttctaatcg aatcatacta agctcctttc aaaatcagca
     4501 gcgacatctt attttctatt ctcatttgcc gatatagtag caatatggca ttccctagaa
     4561 ataggaagaa aaccagcagg cacataagag gattctgtgt taacagggca ctaatcacca
     4621 atccaacaaa gaaaacaagc agctgcgaca gcaaataacg acgatgcagc tcaaaaaatc
     4681 taagaccaga gacgcgctta atgaaaatat cccgtctaaa ttcttcaaag tagagaaggt
     4741 tcattgtgtt aaacatcaac atagaggtcg ctatccctaa tatagctcct gcaatcatca
     4801 accaaatctc cctacgaaga ttgttcaaca atgtctcata aatgcgatag ccagttttta
     4861 gctctcctac ccagttctca ataccgtttt gcttgatgag cgtttgagta tctgccaact
     4921 gatcgaaaag gaaataattt tgtaaagcaa cctcccaaaa ggcataggct tgttcgccag
     4981 ttgacttagg cgtcaaaaca acaataatgg gatcccttaa aaactgctga taggatatcg
     5041 gtgttgtgtt ataaagaaag cgttcctggc ctgtctttgt ataagaaaca gtagcagtca
     5101 tcggctgatg accctcacct gaagcaagcc cagttacagc tgattcaaag accgattggt
     5161 actgtgcagc ctgtgttttc aaatgctctg gtaaaagaag gacaaattct ccaagggaca
     5221 gctgattgat tttttcacta atatcaggtg ccacctcaac tttttggtgc ttcacatatt
     5281 gaggcgttac aagcagcaca ttcccttgtg gactgtaatc attccaacta gaagaggctg
     5341 ttagcataga gaggcctgat tgcaggtcgc gctcgactag gtaatgacga gacaggatcg
     5401 ctccatgctc tgaaacagcc tgatccataa catgaaacca agtcttttgt ttggcaatag
     5461 cttccttcgt atttccaata tctaagccat cacgtcctat taaaagagta accagcctat
     5521 cctcttgtag ccaagcagcc tgcccctgct tctgctgtct ttcagcctgg acataaagaa
     5581 gggtccggct agcgccaaag gaaacaacca gcactgccaa caattgggca attaaaatca
     5641 agctaatgat acctctgaca ggtatctgac ctttaatcac ctgcatcaaa tgcactcttt
     5701 taatcccaat tacaaataaa ccagcaaaga aaagggcaat agctatcagc aaaagattat
     5761 agcaaacaag acctatccca atcaggtaaa gaacaagcgg tgaaaaagac ataagctgac
     5821 tcataatagc cgccaggcta aggccaagta gtaggcctag acagcaatag cacacatcag
     5881 acctgattgg ataaagaaag atctgccagc gacgttcacc tgaaatcaag cggataccca
     5941 ctgctcgcag cgtgcgaata tggccaatca aggtcaaagc cccaaaggtt agacagaata
     6001 tcacaatccc taaagcctga gaaccactgc taaaaatcaa aacgagagtc cctaaaaatg
     6061 aaggcttcag cgctgtcatt ttggtcatac cgagcccagc taatgtgtct cttagtcgct
     6121 ctacagtcaa gccgccttta agaataaagt aattattctc cacactaagc cttgatggtt
     6181 cctcaataac cttttcagct agtccaccag gtagctttcc cttgccaaat aaggtatagg
     6241 tcacaatagg tgtaccttct ggccctggct cctggtgctg cattgcaatt aagctgtctg
     6301 tttcatctgc tagacgggtt aagcctgctt caacctgatt atagcttgcc ttaggcgaag
     6361 catctaaaac aacaacagac ggataataat gagaaacaaa ggtatctgac cagatcgtaa
     6421 atacccaaac caaaaagagg ctaactagta tattagacaa tatgataaac agtctcttca
     6481 taacccactc cttaccttaa aagggacgga gtctctccgc ccctaataaa cacacactga
     6541 cctgcctatt tccctgcatc aaaggtcacg tgctctccaa aattagtatt gataaaagca
     6601 taggagtagt aaccagcacc agaccatgca cgcctctgat tatcacgtcc tgagctctcc
     6661 acaaaggacc ggtgagaaga ggtcagaagg tcacctattg aaaacgcctt caatcataaa
     6721 ggacatggcg attaccacaa taccactcaa atcattaact atttaacaaa aatataccat
     6781 attctgttaa cgtttacaat gttatattta
//
LOCUS       DARYXW010000097         6750 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.097, whole genome shotgun sequence.
ACCESSION   DARYXW010000097 DARYXW010000000
VERSION     DARYXW010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6750
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.097"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(308..4024)
                     /locus_tag="TV191_001686"
     CDS             complement(308..4024)
                     /locus_tag="TV191_001686"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pullulanase"
                     /protein_id="HEL1508178.1"
                     /translation="MMKRLRENQALFEERQLFGIRKLKLGVASVAIATAFSLGTASGQ
                     ITAAAESLTSVEPADGAVMVKSEAADQGSNELPEATDISDIAGISDVTKVSAAVNADT
                     VKEVQPVAVPLVEDQAHEETTDQSQPSSSIVSVTTDSSLETPEATSSEEPIAEQTLRL
                     HFKTLPAQDLSSLGLWVWDDVETPSDQLGGWPTGATNFSLAKTDDYGYYMDVKLSANQ
                     ANKVSFLINNTKGDNLTGDRTIDLLSPKMNEVWIDGQELSYYRPLAQGYIRINYYRSD
                     GHYDNKSLWLWGSADASMTSQQGAWPDGIDFKQVGRYGAYIDVKLADTNELGFLLLDE
                     RQTGDAVKIQPNDYIFKDLKNHTQIFLKDEDPTIYTNPYFVNTVRLIGAQQVSPSSIE
                     ASFTTLADVDKESLLKELKISTDSKEAVAITDITLDEKTHKAVITGDFSQAVATYTVT
                     FHHESFQARPNWQYKDSLYAYDGELGARVREAGAKVDLTIWSPSADKVSLVLYDKADQ
                     TKVIGNLALAKGDKGEWSITLSADSGLGISDYRGYFYHYEITRNGKSVLVLDPYAKSL
                     AAWNSELAKTDPSYKVAKAAIVDPAAIGDKELAFADIKGFHKREDAIIYEAHVRDFTS
                     DQAIANDLKAQFGTFAAFVEKLDYLKELGITHVQLLPVMSYYFVNELANKERMLTYSS
                     SDNNYNWGYDPQSYFALTGMYSTDPTDPAKRIEEFKQLVNEIHKRGMGVILDVVYNHT
                     ANVDIFEDLEPNYYHFMNADGTARTSFGGGRLGTTHYMSRRVLVDSITYLVDEYKVDG
                     FRFDMMGDHDAAAIEKAFLAAKALNPNIIMLGEGWVTYQGDEHMPEQPADQSWMSQTD
                     TVASFSDDFRNQLKSGFPNEGSPAFITGGARDIMTIFHNIKAQPTNFLADDPGDVIQY
                     IAAHDNLTLFDIIAQSIKKDPSVAANAAEIHRRLRLGNLLVLTSQGTPFLHAGQEYGR
                     TKQFKDEAYKGKVADDKVPNKSHLLVNEDGTPFEYPYFIHDSYDSTDAINHFDWAKAT
                     DTERYPESTTSQAFTKGLIALRRSTDAFRLASKAEIDQKVKLITVPNEHGIKAQDLVI
                     AYQTTASNGDVYAVFVNADSNDRTIRLTGEFQALLAGEVIVDAKQAGTEALASPEGVV
                     LTKDGVKLSGLTATIIRLRASQSDKGTLGAMTDQAAHHQEKLVAAQTAGEVSQFSAKT
                     LPKTGTSQLDALLALAGSGILAGLGGLVSKSKRR"
     gene            4504..5049
                     /locus_tag="TV191_001687"
                     /pseudo
     CDS             4504..5049
                     /locus_tag="TV191_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003030066.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1595 family transposase"
     gene            5130..5585
                     /locus_tag="TV191_001688"
     CDS             5130..5585
                     /locus_tag="TV191_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508179.1"
                     /translation="MVKHAKTNLHFELERSISRKVDSKLIAYQVSLSDGFYDKYTKLW
                     DKTYSFDFVINHRAFYAQLTKRCVYDVLLQTLEKISRKAIAKQLAELEALVDVSESKE
                     DFQIFFEKKYKLSFPDLKNCVYPKKKELSDFDQNLWIALHYNPRKERDT"
     gene            5585..5872
                     /locus_tag="TV191_001689"
     CDS             5585..5872
                     /locus_tag="TV191_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508180.1"
                     /translation="MTTWYDYMVRASEHSGSDGDLWFRYLYKVIKDKETKLTTDDVEQ
                     LLKNPNLTPFQKVTLQDALTEGTHTREHVLQANRKSQPKDILKLFREGNYG"
     gene            5865..6413
                     /locus_tag="TV191_001690"
     CDS             5865..6413
                     /locus_tag="TV191_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter peripheral membrane
                     component"
                     /protein_id="HEL1508181.1"
                     /translation="MDKKILFKALNTELAKENISLDIICVGGFVLEYYNLRGTQDIDA
                     FYQEGVNIRQMIKKVGDEFGVNEPDELWLNNSVANLNRIPPKTICETVFHYSNLIVLV
                     PPLSYILGMKLESGRDRDRQDAGDIIKLANIRSPKKLINTLEEYDFQPDISMILEVFE
                     IAYGMEWLANYMTEHPEEFRHY"
     gene            complement(6592..>6750)
                     /locus_tag="TV191_001691"
     CDS             complement(6592..>6750)
                     /locus_tag="TV191_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1508182.1"
                     /translation="EAQKGDKPAVPKAMEHKLPSTGEATAPFFTAAALAVLASLGVAV
                     VSRKRKKH"
BASE COUNT         2038 a         1502 c         1325 g         1885 t
ORIGIN      
        1 tcaatacacc cttaaccatt agaccgtcca atctgccaaa agttacagat taatttaatt
       61 tttagtataa gctgtcatca agtcagataa atagtaatga tctatcatct tattattgac
      121 tcaaacgaca aattatattg cattttagta taagctgtca tcaagtcagg taaataacaa
      181 ggacatatca tctaacattt gatccagaca aaaaagacct gattctgtaa tatacagaac
      241 caagtctttc tcaatagaca ttgactagat gattgattta tagcgacata gctagatagg
      301 ctatgactta ccgtcttttg gatttggaga caagcccgcc aagacctgcc aagataccac
      361 tgccagcaag agccaataaa gcatctagct gactagtgcc tgttttaggg agagtcttag
      421 ctgagaactg agaaacctct ccagcagtct gagcagcaac taatttctcc tgatgatggg
      481 ctgcttgatc agtcattgca cctaaagtcc ccttatcaga ctgggacgcc ctaagacgga
      541 taatggtagc tgttaagcct gatagcttga ccccgtcctt ggttagcaca accccctcag
      601 gacttgccag cgcctcggtg cctgcttgct tggcatcgac gataacctca ccagcaagaa
      661 gagcctgaaa ctcaccagtt agcctaatgg tacggtcatt gctatcagca ttgacaaaga
      721 cagcataaac atcaccattg cttgctgttg tctgataagc aatcaccaaa tcctgtgcct
      781 tgatcccatg ctcatttgga acagtgatca gcttgacctt ctggtctatc tcagccttac
      841 ttgccaagcg aaaggcatct gtcgaacggc gcagcgcaat caatccctta gtaaaggcct
      901 gacttgtcgt gctttcaggg tagcgctctg tatccgttgc ctttgcccag tcaaaatgat
      961 taatggcatc tgtcgaatca taggaatcat gaataaagta tgggtattca aatggtgttc
     1021 cgtcctcatt gaccaagagg tgtgatttat ttggcacctt gtcatcagcg accttgccct
     1081 tataggcttc gtccttaaat tgctttgtac gaccatattc ctgaccagca tgtaggaaag
     1141 gggtgccttg agaggttagc accaagaggt tccctaggcg caagcgacga tgaatctctg
     1201 ccgcatttgc tgcaacagac ggatcctttt taatagactg ggcgataata tcaaacaagg
     1261 tcaggttatc atgtgcagcg atatactgaa tcacatcacc cggatcatca gccaaaaagt
     1321 tagtcggctg agccttgata ttatgaaaaa tggtcatgat atccctagca ccgcccgtaa
     1381 taaaggctgg agagccttca tttggaaagc ctgatttgag ctgattgcga aaatcatctg
     1441 agaaggaggc aacggtatct gtctgtgaca tccagctttg gtccgcaggc tgctcaggca
     1501 tgtgctcatc accctgatag gtgacccagc cctcaccaag catgatgata ttcggattaa
     1561 gtgccttagc tgctaaaaag gctttttcaa tagctgctgc atcatggtcc cccatcatgt
     1621 caaaacgaaa accatcaacc ttatactcat ccaccagata agtaatcgaa tccaccaaaa
     1681 cacgacgact catgtaatgc gttgtcccaa gtcgtccacc accaaatgag gtcctagcag
     1741 tgccatcagc attcataaag tgataataat tcggctccag gtcctcaaaa atatcaacat
     1801 tagctgtatg attgtagacc acatcaagga taacccccat accacgctta tggatttcat
     1861 taacaagctg cttaaattcc tcaatgcgct tagctgggtc ggttggatca gtcgaataca
     1921 taccagtcaa ggcaaaatag ctttgtggat catagcccca gttgtaatta ttatcacttg
     1981 agctgtaggt cagcatacgc tccttgttgg ccaattcgtt gacaaaataa tagctcatca
     2041 caggcagcag ttgaacatgc gtaataccaa gctccttgag ataatccaac ttttcaacaa
     2101 aggcagcaaa agtcccaaat tgagccttta gatcattagc aatcgcctga tctgaggtaa
     2161 aatcacgaac atgtgcctca tagataatgg cgtcctcacg cttatgaaag cccttaatat
     2221 cagcaaaggc cagctcctta tccccaatag cagcaggatc aacaatggcc gccttagcca
     2281 ccttatagga cgggtctgtc ttagcaagct cgctgttcca tgccgctaac gatttggcat
     2341 aagggtccag cacaaggaca gacttgccat ttctagtaat ctcataatga tagaaatagc
     2401 ctctataatc tgaaatccca agtccgctat ctgctgatag agtgattgac cactctccct
     2461 tatcaccctt tgctagagcg agattaccaa tcaccttggt ctgatcagcc ttatcataca
     2521 aaacaagtga caccttatca gcacttggtg accaaatcgt cagatcaacc ttagcacctg
     2581 cttctctcac acgcgctcct agctcaccgt cataagcata caggctatcc ttgtattgcc
     2641 aatttggcct agcctggaag ctctcatgat gaaaggtcac cgtataagtg gccactgctt
     2701 gactaaaatc acctgtgatg acagccttat gagtcttttc atctaaggtg atatcagtaa
     2761 tagcaactgc ttccttactg tcagtgctga tttttaattc ttttaaaagg ctttccttat
     2821 ccacatctgc tagagtcgta aagctcgcct caatactgct tgggctgacc tgctgagcac
     2881 cgattaatct aactgtatta acaaaataag ggttcgtata aatggttgga tcctcgtctt
     2941 tcaagaaaat ttgggtgtga ttctttaaat ctttaaaaat ataatcattg ggctgaattt
     3001 taacagcgtc acctgtctga cgctcatcta gcaagagaaa gcctagctca ttggtatcag
     3061 ctagcttgac atctatataa gcaccatatc gaccgacctg cttaaaatca ataccatctg
     3121 gccaagcgcc ctgctgacta gtcattgacg catcagcact tccccaaagc cagagcgatt
     3181 tgttgtcata atggccatca ctgcgataat aattgatacg gatatagccc tgagccagcg
     3241 gccgatagta agacagctcc tggccatcaa tccagacctc attcatctta gggctgagaa
     3301 ggtctatggt tcgatcgccc gtcagattgt ctcccttagt gttattgatc aaaaagctaa
     3361 ccttattggc ttgattggct gaaagcttaa cgtccatgta atagccatag tcatctgtct
     3421 tcgctagact aaaattggta gccccagtcg gccagcctcc cagctgatca gatggtgtct
     3481 caacatcgtc ccacacccaa agaccaagcg aggataggtc ttgagctggc agggtcttga
     3541 aatgcagccg caaggtctgc tccgctatcg gctcctctga gcttgtagct tctggtgtct
     3601 ctagagagct gtctgtcgta acagacacta tcgatgatga aggctgagac tggtctgtag
     3661 tttcctcatg cgcctgatcc tctacaagag gtacagctac tggctgaact tccttgacag
     3721 tatcagcatt gacagcagct gacaccttag tcacatcaga aataccagca atatcactaa
     3781 tgtcagtagc ttctggtagc tcatttgagc cttggtcagc agcctctgac ttgaccatga
     3841 ccgcaccatc agcaggctca acactcgtca gactctcagc tgctgctgtg atctgcccac
     3901 tagctgtccc caaagaaaaa gcggttgcaa tagctaccga agccactcca agcttaagct
     3961 tacgaatgcc aaataattga cgctcttcaa acagcgcttg attttccctt aaccttttca
     4021 tcattcctcc gtccttatcc tgatagttat taacacctta agtatacaaa agaaatcaca
     4081 atagtgcaat cgttttcttt attgaaaaca atgatattta tgaacaaatt agacaagaat
     4141 caacgcaagc gatttcctta ctgataaata cctgctcccc tcactaagac cagcccactg
     4201 caaagcagaa aagtagccta aagagcctta gtaacagata aatgagctta atgttgcttc
     4261 atcaactagc tggctgcaac cgttttgctc tgatgtggta acgtcttgtc atcatgacta
     4321 agcttgacaa aaaacgctgt tagttacata atcaacggtg cttggtagcc ttccattact
     4381 cctttgattg ttatacccta atgatacaca aaacctcagt ttttatagta gaatattaca
     4441 ctttgttttg acaaagatgt ttaatcttgc taaaataaac ttatcaatga gggagtacca
     4501 atgatgacat tcgaattcac atcgttattc gatttacaaa ctgcttttcc aacagagcag
     4561 gcttgcataa atcatttaga aaatatcact tggggtgacg tggtgatcag cccttttgac
     4621 gctacctcaa aggtctataa atgcaaggga aataaatacc gttgcaagaa tacagggaag
     4681 tatttcactg tcaaaacagg tactcttttt gataatacta agattaagct acaaaaatgg
     4741 tttatggcaa tctggcttgt gacttctcac aagagaggaa tctcctcagt gcaattatca
     4801 aaagagattg cagtgacaca aaaaacagca tggttcatgt tacagcgtat tcgtaaatgc
     4861 tttggctctg aaaactgaga tccacttggt gacgtcgttg aagtagataa aactgatatt
     4921 gatggtaaaa ataagaacca ccatgatcct aagaaggcaa aaacgttcaa gaaccatcct
     4981 tctctgaaag ataagtcggc agttattgga atggtgcaac aaaaaagtaa ggccaacgct
     5041 catacaatac tcgtgattac tctgatagtc ggcgttttat cttttatcag ctaatgctga
     5101 tatgcgaaca acttataagg agctgatcaa tggttaaaca tgcaaaaact aacctacact
     5161 ttgaattaga aagatctatc tctcgcaaag ttgatagtaa attgatagcc tatcaagtca
     5221 gtctttcaga tggcttttat gacaaataca ccaaattatg ggataaaacc tattcatttg
     5281 attttgtcat caaccatcgt gcgttttatg ctcagttgac caaaagatgt gtttacgatg
     5341 tccttttgca aactttggaa aaaatcagta gaaaagccat tgcaaagcaa ctagcagagc
     5401 ttgaagcctt ggttgatgtt tcggaaagta aggaagactt tcagatattt ttcgagaaaa
     5461 aatacaaact atcatttcct gatttgaaga attgtgttta tccaaagaaa aaggaacttt
     5521 ccgattttga tcaaaacctc tggatagctc tacattataa ccctagaaag gagagggata
     5581 cataatgaca acatggtatg attacatggt aagagccagc gaacactctg gaagtgatgg
     5641 agacctctgg tttcgttacc tttacaaggt tatcaaagac aaagaaacca aactaactac
     5701 tgatgatgtg gagcagttat taaaaaatcc gaatctaact ccttttcaga aggtaactct
     5761 gcaagatgct ttaacagaag gtacgcatac aagagagcat gttttacagg caaaccgtaa
     5821 aagtcagcca aaggatattt tgaaactctt tagagaggga aactatggat aaaaaaatct
     5881 tattcaaagc tctgaataca gaactagcta aagaaaatat tagccttgac attatctgtg
     5941 tcggtggttt tgtccttgaa tattacaatc tgcgaggaac acaagatatc gatgcctttt
     6001 atcaagaagg tgttaacatc aggcagatga tcaaaaaggt gggagatgag tttggcgtta
     6061 atgaacctga tgagctttgg cttaataatt cagttgccaa tcttaataga ataccaccta
     6121 aaacgatttg tgagacagta tttcactatt ctaacctaat tgtccttgtc ccacccttgt
     6181 cttatattct tggaatgaag ctagaaagcg gacgagatag ggatagacaa gatgccggag
     6241 acattattaa gctagctaat atccgttccc ctaaaaaact tatcaataca cttgaagagt
     6301 atgattttca acctgatatt tcaatgattt tagaagtctt tgaaatagct tatggcatgg
     6361 aatggttagc aaactatatg accgaacacc cagaagaatt taggcattat taaaagacga
     6421 tttctgtttg gaagtcgcct tttttgatgt ttttgaaaac accttgagat tagtctaaac
     6481 taatctccat aagcaaaaaa cagcttagcc ccgtctggga gtaagctgtt tttgctgtaa
     6541 tgtatgagat aattaggcta acatcaatca ttacataaag ggaataaagg gttaatgttt
     6601 cttgcgtttg cgtgatacta cagctacgcc tagacttgcc aatacggcaa gggctgctgc
     6661 tgtaaagaat ggagctgttg cttctcctgt tgacggaagc ttgtgttcca ttgctttagg
     6721 taccgctggt ttatctcctt tctgtgcttc
//
LOCUS       DARYXW010000098         6728 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.098, whole genome shotgun sequence.
ACCESSION   DARYXW010000098 DARYXW010000000
VERSION     DARYXW010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6728)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6728)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6728
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.098"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(87..3197)
                     /locus_tag="TV191_001692"
     CDS             complement(87..3197)
                     /locus_tag="TV191_001692"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEL1508183.1"
                     /translation="MFAQLDTKTVYSFMDSLIDLDHYFKQAKRLGYQAIGIMDQDNLY
                     GAYHFIKGCQRHGLQPILGLEVAITVKEQALTLKLVAKNDTGYQQLLKLSTEKMSGDL
                     DLDTLVQYLEGIAVIVPFSQSLRDLGLPFDYFIGIDEASDLSKIDSTERLIPLRTVRY
                     FDNAETETLQMLHAIRDNISLADTALVAKDQFLAPCQEMTAIFQEKCPEALVNLVNLT
                     ASIAYHFDTDLKLPRFNRDKPAKEELRELTESGLREKQLWKEPYQFRLAEELAIISDM
                     GFDDYFLIVWDLLRFGRSRGYYMGMGRGSAAGSLVAYSLRITGIDPVKNNLLFERFLN
                     KERYSMPDIDIDLPDIYRSEFLHYVRDRYGSEHSAQIVTFSTFGPKQAVRDVFKRFGV
                     PEYELTSLTKKIGFKDTLSTVYEKNIAFRQTINSRLEFQKAFEIAKRIEGNPRQTSIH
                     AAGIVMSDDHLTNHIPLKKGEDMMVTQYDASAVEANGLLKMDFLGLRNLTLVQKMQEK
                     VVNDYGLSIDIEAINLEDPETIALFARGDTKGIFQFEQHGAISLLKRIKPTSFEEIVA
                     TTSLNRPGASDYTQNFIKRRQGQENIDLIDPVIAPILEPTYGIMLYQEQVMQIAQVYA
                     GFTLGKADLLRRAMSKKNLVEMQRMQEDFLTGARALGRSEETARLLFARMEKFAGYGF
                     NRSHAFAYAALAFQLAYFKAHYPEVFFDVMMNYSSSDYITDALDFGFEAAQVTINTIP
                     FNDKIERHKIYMGLKNIKGLPREFSYWIIENRPFTSVESFLCSIPEKYQKTSFLEPLI
                     KIGLFDGFEKNRQKIINNLEGLLTFVNELGSLFADSSFSWVETEDYSAAEKYYFEQDL
                     LGVGMSKHPLLAVAEKSTVAVTPITKLVKDTEATLLVQIDAIRVIRTKSSGQQMAFLS
                     VTDTKQKLDVTLFPEQYAVYKQDLKEGHIYYINGRVKERDNRLQLVCHQLRLAQSQRY
                     WLLVENHQHDAAISDILTAFSGETPVIIHYQEGKETLELNHIRVDVSKDLEEAISPYV
                     LKTVFR"
     gene            3439..3810
                     /locus_tag="TV191_001693"
     CDS             3439..3810
                     /locus_tag="TV191_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1508184.1"
                     /translation="MSWKFDEKSPIYAQIAQHIMLQIVSQEIKSGDQLPTVREYAEIA
                     GVNPNTMQRALTELDREGIVYSQRTAGRFVTDNQELIARKRRELAINELKSFISNMIK
                     IGFERSEIIPVLSTFLEEGSN"
     gene            3810..4508
                     /locus_tag="TV191_001694"
     CDS             3810..4508
                     /locus_tag="TV191_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1508185.1"
                     /translation="MAQLLQLHHVSKSYKKQLAIDDLTITIPSGKIIGLLGPNGSGKT
                     TLIKLINGLLQPDKGDIVIDGFRPSVETKKIISYLPDTTYLNESMKIKDMLDFFGDFY
                     ADFDRDKATSLLKDLDLDAEERFKNLSKGNKEKAQLILVMSRKAKLYILDEPIGGVDP
                     AARDYILKTIINNYSEQASVIISTHLISDIEPVLDEAIFLKNGKLCLSGNADDLRVQH
                     QQSIDSLFREIYKV"
     gene            4518..5312
                     /locus_tag="TV191_001695"
     CDS             4518..5312
                     /locus_tag="TV191_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1508186.1"
                     /translation="MFGKLLKYEFRSIGKWYFALNAGVIAIAIVLSFTINTLTNNPDE
                     VGLTTSLANKMVPLTLSLTFGSLIAGSFLSTLLIIINRFNKNVFGREGYLTLTLPVTA
                     HQIILSKLLASFVCSIFNGINLLIGIFILIAPTVDFTYLLKVLKTIMKPENLVENASI
                     LIYMLLSTITSILLIYLAISIGQLFSNRRGLMAFCAYFILVIIIIVVMTYLNDAFFTV
                     NPNSSDSLLYFGDHTAISILNIEQLVEGIILYVATHFIIKNKLNIQ"
     gene            complement(5359..5970)
                     /locus_tag="TV191_001696"
     CDS             complement(5359..5970)
                     /locus_tag="TV191_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEL1508187.1"
                     /translation="MRNNELKPYVIWQKVIKLLGSLALVGSFLLAFWFYRLGILNDSN
                     ALKDLVHSHKVFGPLVFVGVQIVQIVFPIIPGGMTTIAGFLIFGPLLGFLYNYVGIFI
                     GSVILFLLVKTYGRRFILLFIEEQTFYKYERKLEMPYYERLFILCMLSPISPADIMVM
                     ITGLTEMSLKRFVTIILITKPLSIIGYSYLFIFGKDLILWFFH"
     gene            6061..6409
                     /gene="ssrA"
                     /locus_tag="TV191_001697"
     tmRNA           6061..6409
                     /gene="ssrA"
                     /locus_tag="TV191_001697"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
BASE COUNT         2085 a         1454 c         1191 g         1998 t
ORIGIN      
        1 ggttgagtaa ggtgtggact aaaacaagtg ataaagtcgg gattatagca cattcgtttg
       61 caaattactt cactaattcg ctatttttat cgaaaaaccg ttttcaacac gtaggggcta
      121 atagcctcct ccaaatcctt actaacatca accctaatat ggtttaactc taaggtttct
      181 ttgccttctt gataatggat aataacagga gtctcccctg aaaaggctgt taatatgtca
      241 gaaatagcag catcatgctg atggttttca accaatagcc aatacctttg actctgagct
      301 aatcgaagct ggtgacagac tagctgcaag cggttatctc tttcttttac cctgccattg
      361 atatagtaaa tatgcccctc ttttaggtct tgcttataga cagcatattg ctcaggaaaa
      421 agggtaacat ctaatttctg tttggtatca gtaacactca aaaaggccat ctgctgtccg
      481 cttgattttg tccgaataac cctgatcgca tctatttgaa ccagcaaagt agcttctgta
      541 tccttcacta actttgtgat tggtgtgact gctactgtgc ttttttcagc gacagctagc
      601 aaggggtgct tgctcatgcc aacaccaagc aaatcctgct caaagtaata tttctcagca
      661 gctgaataat cctcagtctc tacccagcta aaggaggaat ccgcaaaaag tgatcccaat
      721 tcattgacaa aggttagcag tccttctaag ttgttaatga ttttttggcg atttttttca
      781 aacccatcaa acaggcctat tttgataagg ggctctaaga agctggtttt ctggtatttt
      841 tcaggaatgc tgcacaaaaa gctttcaaca ctggtaaagg gcctattttc aatgatccaa
      901 tacgaaaatt ctctaggaag acccttgatg ttttttaagc ccatataaat cttatgacgc
      961 tcaatcttat cattgaaggg aatggtgttt atcgtcacct gcgcggcctc aaagccaaaa
     1021 tctaacgcat ctgtgatgta atcactgcta gaataattca tcatgacatc aaaaaatacc
     1081 tcaggatagt gcgctttaaa ataggctagc tgaaaggcta gggcagcata agcaaaggca
     1141 tggctgcggt taaagccgta gcctgcaaat ttttccatac gtgcaaacaa tagtctggct
     1201 gtctcctcag agcgacccaa ggctctagca ccagtcagaa aatcctcctg cattctttgc
     1261 atctcaacga ggtttttctt agacatagca cgccgtagca aatcggcctt tccaagtgta
     1321 aagcctgcat aaacttgagc aatctgcata acctgctcct gataaagcat gataccatag
     1381 gttggctcta atatcggagc aatcaccgga tctattagat caatgttttc ctgtccctgc
     1441 cggcgcttaa taaaattctg cgtgtaatca cttgctcccg gtctatttaa gctggttgtc
     1501 gcaacaattt cctcaaagct agtcggcttg atccgtttta acaggctaat cgcaccatgc
     1561 tgttcaaatt gaaaaatgcc cttggtatca cccctagcaa acaaggctat cgtttcagga
     1621 tcctctaggt taatagcttc aatgtcaatt gaaagaccgt aatcgttgac caccttttcc
     1681 tgcattttct gtacaagcgt caaatttctc agaccaagaa aatccatttt cagcaagcca
     1741 ttagcttcaa cagcactggc atcatactga gtcaccatca tatcctcccc cttttttaag
     1801 ggaatatggt tggtcagatg gtcatcactc atcacgatac cagcagcgtg aatagaggtc
     1861 tgtcttggat tgccttcaat gcgcttagct atctcaaatg ccttttgaaa ctctaagcgg
     1921 ctattaatgg tctgtctgaa ggctatattt ttctcataaa cagtgctcag ggtatccttg
     1981 aacccaattt ttttagttag gcttgttagc tcgtattctg ggacaccaaa gcgtttgaac
     2041 acatcacgaa cagcctgctt aggaccaaaa gtcgaaaagg taacaatctg agctgagtgc
     2101 tcactaccat accggtctcg aacataatga agaaactctg agcggtaaat atcaggcaaa
     2161 tcaatatcaa tatcaggcat gctgtagcgt tctttattca aaaagcgttc aaacaataaa
     2221 ttgtttttga caggatcaat cccagtaatg cgcaacgaat aagccactag actgcctgct
     2281 gctgaaccac gccccatgcc catataatag cctctactcc ttccaaagcg cagcaaatcc
     2341 cagacaatga gaaaataatc atcaaacccc atatctgaaa taatagccag ctcctctgcc
     2401 agacgaaatt ggtaaggctc cttccataat tgcttttctc ttagaccaga ctcggtcaat
     2461 tctcttagct cttcttttgc tggcttatcg cggttaaatc tcggaagctt taaatcagta
     2521 tcaaaatgat aagcaatcga agctgttaga tttacgagat tcaccaaagc ctcagggcac
     2581 ttttcctgga aaatagccgt catctcctga caaggcgcta aaaactgatc cttggctact
     2641 agagccgtat ctgctaagct aatattatca cgaatggcat gcagcatttg cagagtctca
     2701 gtctcagcat tatcaaaata acgtaccgtt ctaagcggaa tcagtctttc tgtagagtct
     2761 atctttgaca agtcgcttgc ctcatcaatg ccaatgaagt aatcaaaagg aagccctaaa
     2821 tcacgcaagc tctgactaaa aggaacgata actgctatcc cttctaaata ctgcaccaat
     2881 gtgtctaggt ctaggtctcc agacattttt tcagtcgaaa gctttaagag ctgctgatag
     2941 cctgtatcat ttttcgcaac aagcttcagc gtaagagcct gctctttaac tgtaatagcc
     3001 acctcaagac ctaaaatcgg ctgaagccca tgcctttgac agcccttaat aaaatgatat
     3061 gccccatata gattatcctg atccataatc cctatggctt gatagcctaa tcgtttggct
     3121 tgtttaaaat aatggtctaa atcaatcaaa ctatccataa aggaataaac tgtttttgta
     3181 tctaactgag caaacatgga catctccttt agcgttctta ctaccattat actatgaaaa
     3241 agactttact gcccagattt taagctttta atagcagtga tctgtcttta ctgcaccact
     3301 atcagcagga atcccactag cattgcaagc cagtatgtaa ctagagatga cacacaaggc
     3361 ttgacaagtc aatcgttttt ttgtatcatt taattagtac aaatattaat cgcagatttt
     3421 agaaagaaag gagacagtat gtcttggaaa tttgatgaga aatctcctat ttacgcacag
     3481 atagcacagc atatcatgct gcaaattgtc agccaagaga tcaaaagtgg agatcagctg
     3541 ccgactgtcc gagaatatgc tgaaattgcc ggcgttaatc ccaacaccat gcaaagagca
     3601 cttaccgaat tagatcgtga aggcatagtt tactcgcaac gaactgccgg ccggtttgta
     3661 acagataacc aagagcttat cgcgcgcaaa agacgagagc tggccatcaa cgagctcaag
     3721 tcctttatta gcaatatgat caaaataggt tttgaacgtt cagaaatcat tcctgtttta
     3781 agtacctttt tagaggaggg atcaaactaa tggcacaact attacagctg caccacgtct
     3841 caaaatctta caaaaaacaa ttagctattg atgatttaac cataacaatc ccttctggaa
     3901 aaattatcgg cttactagga ccaaatggta gcggcaaaac tacactaatt aagctaatca
     3961 acggactttt acagccagac aagggagaca ttgttattga cggctttaga ccatctgtag
     4021 aaactaaaaa aatcatttct tacttaccag atacgaccta tcttaatgaa agtatgaaaa
     4081 tcaaggatat gctagacttt tttggtgatt tctatgccga ttttgacaga gataaagcga
     4141 ccagtctcct gaaggattta gacttagatg ctgaagagcg ctttaaaaac ctatcaaagg
     4201 gaaataagga aaaggcacag cttatcctcg tgatgagccg caaagcaaag ctctatatcc
     4261 ttgatgagcc tatcggaggg gttgacccgg cagcaagaga ttatattctt aaaaccatta
     4321 ttaataatta ctctgagcaa gcctctgtta tcatttctac tcacctcatc tcagacattg
     4381 agcctgtact tgatgaagct attttcttaa aaaatggtaa gctctgcctt tctggaaacg
     4441 ctgatgattt acgagttcag catcagcaat cgattgattc attatttaga gagatctaca
     4501 aggtttagga ggtaggcatg tttggaaaat tattaaaata cgaatttaga tcaattggca
     4561 agtggtattt tgcgcttaat gccggtgtca ttgctatcgc gatagtcctt tcttttacca
     4621 tcaatacgct tacaaacaat cctgacgagg ttggtttaac aacaagtctg gcaaacaaaa
     4681 tggttcctct cacactctca ttaacgtttg gttctctgat tgccggatca ttcttatcaa
     4741 cgctattaat catcattaat cgctttaaca aaaatgtctt tgggcgcgag ggatacttaa
     4801 cactgacact accagtaaca gcacatcaga ttatcttgtc caagctgtta gcgtcctttg
     4861 tttgcagtat ttttaatggc attaacctat taatcggtat ctttatttta atagcgccaa
     4921 cagttgactt tacctatcta ctaaaggtgc taaagacaat tatgaagcca gaaaacttag
     4981 tcgaaaatgc ttctatcctc atctacatgc ttttgtcaac cataacaagt atactattga
     5041 tttatctagc aatctcaatt ggtcagctat tttcaaatcg tcgtggtttg atggcatttt
     5101 gtgcctattt cattttagtt attatcatta ttgtcgtcat gacttattta aatgatgcgt
     5161 ttttcaccgt caacccaaat agctcagact cgctactcta tttcggtgat catacagcca
     5221 tatctatttt aaacatagag caactagttg aaggcattat cctttacgtt gctactcact
     5281 tcatcatcaa aaacaagctt aatatccaat gataacaaaa agtctagcca ctgcttatca
     5341 ggcaatgcct agactttttt aatggaaaaa ccataggatc aaatcctttc caaagataaa
     5401 aagatagctg tagccaataa ttgatagtgg cttcgtgatt aaaataatgg tcacaaaacg
     5461 cttcaacgac atctctgtca gcccagtaat catgaccata atatctgctg gtgaaatcgg
     5521 agaaagcata cagagaataa acaatctctc ataatatggc atctctaatt ttctctcata
     5581 cttgtaaaag gtctgttcct ctataaacag taaaataaag cgcctaccat aggtcttcac
     5641 aagtaaaaac agaatcacac taccaatgaa gataccaaca tagttataaa gaaaacccag
     5701 caaagggcca aaaatcaaaa agcctgcaat agttgtcata ccacctggaa taataggaaa
     5761 aacaatctga acaatttgca caccgacaaa aacaaggggg ccaaaaacct tgtgactatg
     5821 aacaagatcc ttgagtgcat tgctgtcatt taaaatgcca agcctgtaaa accaaaaggc
     5881 tagcaaaaaa gatccgacta aagccagact tcctaatagc ttaatcactt tttgccatat
     5941 cacataaggc ttcaactcat tatttctcat agcttcatca taccataagc gctatttttt
     6001 tgccatttta aaaaaatttt gctatactag catccgtaag tatctcatac gcctttttat
     6061 ggggttgtta cggattcgac aggcattatg aggcctattt tgcaactcat cggcagatgt
     6121 aaaaatgcca gttaaatata actgcaaaaa ataacacaac ttacgcttta gctgcctaaa
     6181 aaccagccgg cgtgacttct ataggattgc ttgtgtctta ttagaggtct caaaacagca
     6241 agctacgttt aggtgattgt ctagtcacct aaaaagagaa ccctagactc gcaggctgat
     6301 ggcttgagtt atgtgtcctt ggtctgttaa agtaagacat aacctatggt tgtagacaaa
     6361 taggttagca ggtgtttgga cgtgggttcg actcccacca gctccatcaa tacttaccgt
     6421 aagttaccat aacttactaa aaccttgtta aatcaaggtt ttttcttttt gtcctgttcg
     6481 tgggttaccg taagtttcta tgaaagtgat agcaaaaaaa aggccaaaaa atcctttaag
     6541 aacagcttga attttctctt tagctaatct tatatttatt tttttataat acttcttcta
     6601 cttgcttcat tgacagcaca ttatcaaatt ttttcggata attgccctgt attgcctgtt
     6661 atatagacat catttactgc tgctttatag atatcatctg ttatgatatt gtgcttcttt
     6721 acaaaatt
//
LOCUS       DARYXW010000099         6665 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.099, whole genome shotgun sequence.
ACCESSION   DARYXW010000099 DARYXW010000000
VERSION     DARYXW010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6665
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.099"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            88..237
                     /locus_tag="TV191_001698"
     CDS             88..237
                     /locus_tag="TV191_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508188.1"
                     /translation="MPEDLIKQLEAGSEFLAKTCLHSKIIITVDGVRLVETKEFHPVS
                     GTLLD"
     gene            complement(234..434)
                     /locus_tag="TV191_001699"
     CDS             complement(234..434)
                     /locus_tag="TV191_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KTSC domain-containing protein"
                     /protein_id="HEL1508189.1"
                     /translation="MQRQYVSSSNVRSVGWENNTLEVEFNNGSIYHYHNVSQTEYRSV
                     LVGSVGSNIHRLAKIHTYTRIV"
     gene            545..829
                     /locus_tag="TV191_001700"
     CDS             545..829
                     /locus_tag="TV191_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1508190.1"
                     /translation="MDSRLLQMLDEFEAGLIDRKIKVIGMLNNETEIYPLELNKKQIS
                     KMLGVDPKTFDVRFNSHKDFPRIETGGREKYPRDLVIEWYSKNWERTGIR"
     gene            826..972
                     /locus_tag="TV191_001701"
     CDS             826..972
                     /locus_tag="TV191_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508191.1"
                     /translation="MIKKLFNFIFAKPKEESRQPYQQPRGFLDFETGKRIEIDPITRK
                     EYFV"
     gene            1176..1421
                     /locus_tag="TV191_001702"
     CDS             1176..1421
                     /locus_tag="TV191_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEL1508192.1"
                     /translation="MLLTILSNSDEWRVYPEELAKRCRDSVDAVRTQLKALEKAGYIR
                     SYRKSLGGRYGTETHRFCSDTKISDEVFQELLKELNC"
     gene            1583..1966
                     /locus_tag="TV191_001703"
     CDS             1583..1966
                     /locus_tag="TV191_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEL1508193.1"
                     /translation="MDEKKLFENFQLTFGRMISPFEIEDIQKWIHQDNMPIDVVNLAL
                     REAVENNKINWKYINKILVEWHKAGDTTIEKVKERLQRFEDSKEQRHATISNVPSWSN
                     PDYQGPTYDDLKVNPSEVSDGAGDF"
     gene            1947..2180
                     /locus_tag="TV191_001704"
     CDS             1947..2180
                     /locus_tag="TV191_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508194.1"
                     /translation="MAQEIFDGFNALINKMYGRQSSIETFNRFVEYCQKRREENGVEP
                     VLNPINLFAFGVGITTEEANKLRIKRYKQENGL"
     gene            2177..2317
                     /locus_tag="TV191_001705"
     CDS             2177..2317
                     /locus_tag="TV191_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508195.1"
                     /translation="MTKQYRETLIWHRASHKEREKLLDFGLVDKSQYMTLLRQLRKKY
                     AI"
     gene            2326..2532
                     /locus_tag="TV191_001706"
     CDS             2326..2532
                     /locus_tag="TV191_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508196.1"
                     /translation="MTPEQVEKAKIRAKRELETFSIYLDQAIVEYGSTLSPQEVFLAA
                     GFAYLGAGQTDIHAAIEGLYEQIQ"
     gene            2667..3395
                     /locus_tag="TV191_001707"
                     /pseudo
     CDS             2667..3395
                     /locus_tag="TV191_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017827951.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
     gene            3572..4783
                     /locus_tag="TV191_001708"
     CDS             3572..4783
                     /locus_tag="TV191_001708"
                     /inference="COORDINATES: protein motif:HMM:NF018751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1351 domain-containing protein"
                     /protein_id="HEL1508197.1"
                     /translation="MSENLTLFENLNDIKPAEPAELSFDFEFTPAEIKIKGKEKLEEI
                     LAAYAKKYDGYTVTAETFEDDAKVRAKLNTLQKDINNSVKTKLAEYNNPLDDVKQWVN
                     SIIEPIKKITKTIDEGVKHFEEIERQKRANTIKETFEAAIAETGADIDIRLFESNFDD
                     MSAKGYFMADNVRVNTATKKAINKLVAEEVAKKQEHEQALIQISEAAAKADFGPAIYI
                     KRFENGAQLADILQAIADDKLLADKVREEEKRKAELSKRVEEMTALAQREGLQPGKYV
                     KLLEDGKSALVVFETLMDDSKKMQAKIAQKNAEAHQQQIEQTEYMSEASNSGVNELET
                     DKVINNIIKQENALEAKIEPNKSVTKWQGDFKITFPDSETAKLFGGQGGLYEKHGVIV
                     EKLGEWVKIND"
     gene            4776..5612
                     /locus_tag="TV191_001709"
     CDS             4776..5612
                     /locus_tag="TV191_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease-like domain-containing
                     protein"
                     /protein_id="HEL1508198.1"
                     /translation="MTKLTEENYYQDREWLSNSRFKAFLDCEAKALAVENNEWEDTRD
                     ETPLLVGNYLHSYFESPEAHEKFKAENGAKMISSRGVTKGELKKEYKVAQNMIETLET
                     DEIFNLMYHGQSGDNVLKEMIIYGEILGIKVKGKVDSINLTKGYFCDLKTMKSIHSDE
                     WSNDLRKRVPGVAANIIGFKYHIQMGLYQELLRQMTGKTLQPLIIAISKENVPDKELI
                     ELGQTWLDEGLQLFENNVEHVHEVIIGKAEAKSCGRCDYCRSQKKLNRVVDLDDLIAG
                     IF"
     gene            5797..6138
                     /locus_tag="TV191_001710"
     CDS             5797..6138
                     /locus_tag="TV191_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508199.1"
                     /translation="MEQIKITGTDTILILDRVDRAFVIEGNLAERWRFTSKFIKIDDE
                     LSLDEDGELFEIVYDLMLEAKPHNVINLTSSYFAKEHKKDTDEIIKVFAFIEDNKKNI
                     FETLGIRGVLE"
     gene            6135..6647
                     /locus_tag="TV191_001711"
     CDS             6135..6647
                     /locus_tag="TV191_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508200.1"
                     /translation="MSNLVLSLDISTSGTGWALFKGSDLIQSGVLKHKSDSYFERGRY
                     MASKLRLIQSRALKKYDCSFSTIAVEKNSVMGPNQQSMLKIGIVTGIILGRLIADNVV
                     FINVSTWRKHWKFSYKDRSKKAMKAQSKAKAAENFGKIVKDDEADAVLIGAYYVNQGY
                     LDGLETHDYY"
BASE COUNT         2430 a         1106 c         1446 g         1683 t
ORIGIN      
        1 ggccagcagt attttattaa taaattcctt aatcaggaat atctgccagt ttagaaagga
       61 aacaaaacca acgaaaagga gaaaagtatg ccagaggatt taatcaaaca actagaagct
      121 ggttcagaat ttctagcaaa gacatgttta catagcaaga ttattatcac ggtggatggt
      181 gttcggcttg tggaaacaaa agagttccac ccagtgagcg gaactctact agattagaca
      241 atacgtgtat aagtgtgtat cttagctaat ctatgaatat ttgagccaac agacccaaca
      301 agaacagaac ggtattccgt ttggcttaca ttgtgataat ggtaaataga accattatta
      361 aactcaactt ccaaagtgtt attttcccaa ccaacacttc ggacgttact agatgaaacg
      421 tattgacgtt gcataacttt ttctcctttc cgcgatgata gctttattat agcacgcaag
      481 gagaatacaa aaaaagtccg acgggaatcg gactcgacaa taatatttat gaggtaattt
      541 tatcatggat agtagattat tacaaatgct tgatgagttt gaggcgggtc tgatagaccg
      601 taaaatcaaa gtcataggca tgcttaataa cgaaacggaa atttatccgc tagagcttaa
      661 caaaaagcaa atcagtaaga tgctgggagt tgatcctaaa acatttgacg taagatttaa
      721 tagccacaaa gattttccgc gcatcgaaac gggaggtcgg gaaaaatacc cacgagattt
      781 agttattgag tggtatagca aaaactggga aaggacgggg ataagatgat taaaaaacta
      841 tttaacttta tttttgcaaa gccaaaagaa gaatcaaggc aaccttatca acaaccgaga
      901 ggttttctgg attttgaaac aggtaaacga attgaaatag atccgataac aagaaaggaa
      961 tacttcgtat gatgcatcaa attaatatat cgcttagaaa ttttgtcgag actggagaga
     1021 ttgacaacat cttcgacatt tttagaattt tagatttcta ctttcgggag gtggtcagct
     1081 gatgcagtac atttttcaag acgttgagag ggagttacac gagcgttagt aatgagtttg
     1141 tcaacgataa aaaactttat aacaaggaaa agggattgtt gttgaccatt cttagcaata
     1201 gcgatgagtg gcgagtatat ccggaggaat tggctaaacg ttgcagagat agtgttgacg
     1261 ctgtcagaac tcagctaaaa gcacttgaga aagctggata catcagaagt tatcggaagt
     1321 cgcttggcgg gcgatatggt accgaaaccc atagattttg ctcagacaca aaaataagtg
     1381 atgaggtttt tcaagagctg cttaaagaat taaattgcta atgtgcaaat tgctaatgtg
     1441 caaattgcta atgtgcaaat tgctaatgtg caaattgcta atgtgcaaat tgcctaacta
     1501 ataaatacta acactaaata aatactaaat aataataaat actaacaaac aataagcatc
     1561 atcatcaaca gcaggaggag ctatggacga aaaaaagctt tttgaaaatt ttcaactaac
     1621 tttcggaaga atgatatcgc catttgaaat agaagatatt caaaagtgga ttcaccagga
     1681 taatatgccg attgatgttg ttaaccttgc tttaagagaa gcggtagaaa acaacaagat
     1741 caattggaag tatatcaaca aaattttggt ggagtggcat aaagctggag atacgacgat
     1801 tgagaaggtc aaagagaggt tgcagagatt tgaggatagc aaagaacaac gacatgcaac
     1861 tatctcaaat gttcctagct ggtcaaatcc agactaccaa ggcccgacat acgatgattt
     1921 aaaagtaaat ccaagcgagg tgtcagatgg cgcaggagat ttttgatgga tttaatgcct
     1981 taatcaataa aatgtatggc agacaatcta gcatagagac ctttaaccga tttgtcgagt
     2041 attgtcaaaa aaggagagag gaaaacgggg ttgagcctgt attaaatccg atcaatcttt
     2101 ttgcattcgg cgttggaatc acaacggaag aagctaataa attaagaata aaacgctaca
     2161 aacaggagaa tggattatga caaaacaata tcgagagaca cttatctggc atcgggcaag
     2221 tcacaaagag cgtgagaagc tgcttgattt cgggctagtt gataaatcac agtacatgac
     2281 actattacgc caattgcgca agaaatatgc gatttaggag gaaatatgac accagaacaa
     2341 gtggaaaaag caaaaatcag agctaaacga gaacttgaaa cgtttagcat ctaccttgac
     2401 caggcgattg tcgaatacgg aagtacgcta agtccacaag aagtcttttt agcggcaggg
     2461 tttgcctacc ttggtgcagg tcagactgac atacatgcgg ccatcgaggg gttatatgag
     2521 caaatccaat gattttaatt ttagcgatga ctgggaaagc aactatttcg aggtccaagc
     2581 tttgctaggg caagagatag acaagctcca aaacagggtc atagcgctaa gccaggaaaa
     2641 caatagatta aaagcgagga aatgaaatgg caagtgaaat tgtaacaatt caaaaagata
     2701 tcactgatat cgttaattca aaaattagta tgcttcagaa cgaaggtctt gtaatagcgc
     2761 caaactatgc tccagcaaat gctttgaagt cagcattctt taaaatttta aaaaccaaag
     2821 acagaaataa gaggcctgct cttgaagcct gcacaaagga ctcaattgcg aactcgctcc
     2881 ttgaaatggt cacccaagga ttatcacctg caaaaaatca atgctatttt atcgtttacg
     2941 ggaatgagct ccaactgcaa agatcatatt tcggaacaat ggcagtttta ttgcagcaga
     3001 aaaaaattaa atcaattaag tcagaagtta tttatgaagg tgacgatttt gagcttgaaa
     3061 ttgtagatgg tgaaaagaaa ttcaaaaagc atgatactca ttggaaaaat caagacaatc
     3121 caattgaagg ggcttattgc attattgagg atatagatgg taacactaag ctaacactga
     3181 tgacaaaaaa agagattgat aaagcgtggt ctaagacaaa gactggtgga gggacacaaa
     3241 aagaattccc tcaggaaatg gccaaaaaaa cagttatcaa cagagctgct aagtttttta
     3301 tcaatatcag tgatgacagt gacattttgg cagattctat taacaagacc accgcagatg
     3361 aatatattga cgatcgtcaa gtaaaagatg taacggaaac acagtcacct gcacagacac
     3421 tactcgataa catgaagcat gacgaggaaa tgagcaaaat cgaaacgatg caaaatgaac
     3481 aattgatgca tgatccagaa acaggagaaa tcattgatgc agaggttgtt gaggcggacc
     3541 taaaggaatc tgatatggag gagccattct aatgagcgaa aatttaacac tttttgaaaa
     3601 tttaaatgac attaaaccag ccgaacccgc tgagctgagt tttgattttg agtttactcc
     3661 agccgaaatc aaaatcaaag ggaaagagaa gctcgaagag attttagcag cctacgctaa
     3721 aaaatacgat ggctacacag tgacagccga aacctttgaa gacgatgcaa aggttagagc
     3781 aaaactcaat actttgcaga aagatattaa taactctgta aaaacaaaac tcgcagaata
     3841 caataaccct cttgatgatg ttaagcagtg ggttaactca attattgagc caattaaaaa
     3901 aattacaaaa acgattgatg agggtgttaa acactttgaa gaaatcgaac gtcagaagcg
     3961 tgcaaataca atcaaagaaa cctttgaggc tgctattgct gaaacaggtg ctgatattga
     4021 tatccgcttg ttcgaatcta actttgacga tatgtcggct aaaggatatt ttatggctga
     4081 caacgtccgc gtcaataccg ctaccaaaaa ggccattaac aaattggttg ctgaagaagt
     4141 agcaaaaaaa caggaacatg agcaggcgct tatccaaatt tcagaagctg ctgccaaagc
     4201 ggattttgga ccagctatct atatcaaacg atttgaaaat ggcgcacaac tggcagatat
     4261 cttacaagca atcgctgacg ataaactgct tgctgacaag gtgcgcgaag aagaaaaacg
     4321 caaagcagaa ctatctaagc gagtagaaga aatgacagcc ctggcacaac gtgaagggtt
     4381 gcaaccaggc aaatatgtaa aattgcttga agatggcaag tctgctttag tcgtttttga
     4441 aactctgatg gacgattcta aaaaaatgca ggccaagata gcacaaaaaa acgcagaagc
     4501 gcatcagcaa caaatagaac agaccgaata tatgtctgag gcctcaaatt cgggggtaaa
     4561 cgagcttgaa acagacaagg tgataaataa tatcatcaaa caagaaaatg ccttagaagc
     4621 caaaatagaa ccgaataaga gcgtcacaaa atggcaaggt gattttaaaa taactttccc
     4681 ggattcagaa acagctaaac tatttggcgg gcaaggcgga ttatacgaaa agcatggcgt
     4741 gattgttgaa aaattaggtg aatgggtgaa gattaatgac taaattaacc gaagaaaatt
     4801 attatcaaga ccgagaatgg ttgtctaact caagatttaa ggctttcctt gattgtgagg
     4861 ctaaagcttt agctgtcgaa aacaacgagt gggaagatac cagagatgag acaccgcttt
     4921 tggttggtaa ctaccttcac agctatttcg aaagtcctga agctcatgag aaattcaaag
     4981 ccgagaatgg agctaagatg atttccagtc gtggagttac aaaaggggaa ctcaaaaaag
     5041 agtacaaagt agcgcaaaac atgattgaaa cgctagaaac tgatgagata tttaatctca
     5101 tgtaccatgg ccaatctggt gataatgttt tgaaagaaat gatcatatac ggggaaatct
     5161 taggcataaa agttaaagga aaagttgatt caatcaattt aacaaaaggt tatttttgtg
     5221 acttaaaaac gatgaaaagc atacacagcg acgaatggag taatgacttg cgtaagcgtg
     5281 tacctggtgt agcagctaac attatcgggt ttaaatacca tatccagatg gggctctatc
     5341 aagaattact cagacagatg actggaaaaa cgcttcaacc gctaatcatt gcaatcagta
     5401 aagagaatgt accagataag gaactcatcg aacttggcca aacgtggcta gatgaagggt
     5461 tgcaactttt tgaaaacaat gtggagcatg tgcacgaagt catcattggt aaagctgaag
     5521 ctaagtcgtg tggacgttgt gattattgtc gaagtcagaa aaagcttaat agggtggttg
     5581 atctcgatga tttgattgca ggaatttttt aggagatctt attgtattgc aaagtgatgc
     5641 tcggcctttg cagcaacaaa tattttccga gcgagaaagg aaaattgcaa tatcgtcaag
     5701 ttaacaggat tgatgatata aagagttgct acactcgtcc ttgctaatgc tcacacacaa
     5761 ttttagggcg agtgtggatt ttaaaaaggt gaaaatatgg aacaaatcaa aattacagga
     5821 actgacacaa tattaatttt agatagagta gatagggcct ttgtcattga gggtaatcta
     5881 gctgaaagat ggcgttttac tagcaagttt ataaagattg acgatgagct atcgctggac
     5941 gaggacggcg aattgtttga gatagtttat gacttaatgc tagaagcaaa acctcacaac
     6001 gtgattaatc taacatcatc atattttgct aaagaacata agaaagacac agatgaaatc
     6061 ataaaagtat ttgcttttat cgaagataac aagaagaata tttttgaaac ccttggcatt
     6121 cgcggggtgc ttgaatgagc aatctagtat tatcgctaga catctcaaca tctggtacag
     6181 gttgggcctt atttaaaggc tcagacctta tccagagcgg tgtcttaaaa cataagagcg
     6241 actcttattt tgaacgtgga cgctatatgg ctagcaaatt aaggttgatc cagtcacgag
     6301 cattaaaaaa atacgattgc tcctttagca caatcgcagt cgaaaaaaac tcggttatgg
     6361 gtccaaatca acaatccatg cttaaaatcg gcattgtaac tggtatcatc ttaggacgat
     6421 tgatagctga taatgtcgta tttatcaatg tctcaacttg gcgaaagcac tggaagttta
     6481 gctacaaaga ccgctcaaaa aaagcaatga aagcacagtc aaaggctaag gctgctgaaa
     6541 actttggcaa aatagtcaaa gatgatgagg cagatgccgt cttgattggt gcatactatg
     6601 tcaatcaagg ctatcttgat ggattggaga cacatgacta ctactaaaaa acacgttgtg
     6661 aggat
//
LOCUS       DARYXW010000100         6627 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.100, whole genome shotgun sequence.
ACCESSION   DARYXW010000100 DARYXW010000000
VERSION     DARYXW010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6627)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6627)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6627
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.100"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(<1..490)
                     /locus_tag="TV191_001712"
     CDS             complement(<1..490)
                     /locus_tag="TV191_001712"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508201.1"
                     /translation="MKKLVLASAAALVLAGATVSTGTVSANSSRYNYTGWNQGGYSWK
                     YLRLRNKNPYSRRTLTEDYSDQRKNEAKDSIKELSKLSDKEKKNFADRIDALTDTYAI
                     SSILSEAKNKNNDYLEFDKEYEALFNSNKYKLEIEKIKDRVYFDEGYSARQGINDLKS
                     LEN"
     gene            complement(677..3178)
                     /locus_tag="TV191_001713"
     CDS             complement(677..3178)
                     /locus_tag="TV191_001713"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEL1508202.1"
                     /translation="MTFYNHKAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREINTTDPSYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLADLEEVDWPESIKD
                     MQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDSITTAEQ
                     AQAVAEYKRQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAIMAVPAHDERDWAFAKQFNLEIIPVLEGGNVDEAAYTEDGIHINSDFLDGLDKACA
                     IAKMVAWLEETGVGHEKVSYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPEQDLPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NDEQLADKDLLKQWLPVDIYIGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVDKRDGSFFHMETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGARKFLDRVYRLITTKEIVAENSGALD
                     KAYHETVKAVTEQIEGMKFNTAIAQLMIFVNAANKEDELYVAYAKGFVQLLAPFAPHL
                     GEELWQILTASGQSISYVAWPTHDDSKLVENDVEIVVQIKGKVKAKLVVAKDLSREEL
                     EKVALAHDKIQAEIAGKEVAKVIVVPNKLVNIVVK"
     gene            complement(3767..4630)
                     /locus_tag="TV191_001714"
                     /pseudo
     CDS             complement(3767..4630)
                     /locus_tag="TV191_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514825.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(4912..6429)
                     /locus_tag="TV191_001715"
     CDS             complement(4912..6429)
                     /locus_tag="TV191_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1508203.1"
                     /translation="MSIENLFTKQQWRELELITLLSETKNPLYYKDACQMLDCSVLTL
                     QSCITNSVFMEDLGKLFYKDSQFHIHYNHQSGLKEVYRRALLESPSLQLMSALFFDDF
                     ASLDDLAEALFISLSTLKRLIRKTNLYLKEHFDIIISAKPIRVVGDEYNIRLFYIKYF
                     SEAYTFSEWPFASLLNENHHEQFVQLMASLIEVKIDFAIFRQLKLLSAVNLIRYLKGF
                     KIGKHKALSSLSLELLQDSQEMKKLSHLFVLKFSVPLDELVLSEMFSNYLDDDLVLEK
                     SLQVDKVKEEVPGPQSLLSWIDLLSEMEGATGIVLPNKYEVARYLHATVILGVEDISE
                     SFLIYDYKKDYLAFFKEHYTYVYFRFTDYVKRLFKDGDMELATNLLNNLVYSLLIAWE
                     NFFLTMCELMKKPKLLIIERSHGSTGSFLKKYIGEFFEITIFDKLTIEALCLQHDYDV
                     IITDTVIRGCEHADIFFFSRFVPTVIVAKLNHYLRKRMGSIFETKTTNKLGNIGY"
BASE COUNT         1879 a         1506 c         1219 g         2023 t
ORIGIN      
        1 aattctccag acttttcaag tcattaatcc cttgtctagc tgagtaacct tcatcaaagt
       61 acacacgatc ctttattttc tctatttcta acttatactt atttgaattg aataaagcct
      121 catattcttt atcaaattct aaatagtcat tattcttatt tttagcttct gatagaatag
      181 agctgattgc ataggtgtca gtcaaagcat caattctatc agcaaaattc tttttctctt
      241 tatcactaag cttactcaat tctttaatac tatcttttgc ttcattcttt ctttgatcag
      301 aatagtcttc tgtaagggta cgacgtgaat aaggattttt atttcttagg cgcaaatatt
      361 tccatgagta cccaccttga ttccaaccgg tataattata tcttgaacta ttcgcactta
      421 ctgttcctgt acttacagtt gctcctgcta atacaagtgc tgctgcactg gctaaaacta
      481 attttttcac gttgaaaaat cctccattta ttaaataagt ttagggtttt attttactat
      541 tatcttcaag cttcttcaat atcagtttta atagcgtgtt acaaaacaag aataaccact
      601 catgtaaacg agtggttatc agctttttat agtattgggc tcaaaattat aaggaaggca
      661 ttttttgcta gggtctttat ttcaccacaa tattaacgag cttattagga acaacgatga
      721 cctttgccac ttccttgcct gcaatttcag cctgtatttt atcatgtgct agggctactt
      781 tttctagctc ttctcttgag aggtcttttg ccacgacaag cttagccttg acctttcctt
      841 taatttgaac aacgatttca acatcatttt caacgagctt actatcgtca tgggttggcc
      901 atgcaacata cgagatggat tgacctgaag ctgtcaggat ctgccataat tcttcaccta
      961 ggtgtggggc aaatggggct agcaattgaa cgaagccttt ggcgtatgcc acataaagct
     1021 cgtcctcttt attggctgca ttgacaaaaa tcatgagctg ggcaatagca gtattgaatt
     1081 tcatgccttc gatttgttct gtgactgcct taacagtctc atggtaagcc ttatctaaag
     1141 ctccgctatt ttctgcaaca atttcctttg tcgtgatcaa acggtaaaca cgatctagga
     1201 acttgcgtgc tccctcaagg ccttcttcag accaagcaat ggacgcatca agtggcccca
     1261 taaacatttc atacacacgc agggtatctg ctccgtactg ctccaccaca tcgtctgggt
     1321 tgacaacgtt tttcagtgat ttagacatct tagcaggggc ctgctcaagc tcctcgcctg
     1381 tttccatgtg gaagaagcta ccatcacgct tgtcaacctt atccgttgcg accaaggccc
     1441 cacgatggtc gcgatagctg gttcccaaaa tcatgccttg attaaagagc ttttggaagg
     1501 gctccttggt tggcactaca cccagatcat agagtacctt gtgccagaag cgtgcataaa
     1561 gcagatgaag cactgcgtgc tcagcaccac caatgtaaat atctactggc agccattgct
     1621 ttaacaggtc cttatcagct aattgctcat cattgtgtgg gtcaatatag cgaaggtaat
     1681 accagcttga gccagcccac tgtggcatgg tgttggtctc acgacgccct ttgaccccat
     1741 cctcgcgggt cacctcaagc cagtcagtca agttagctag tggtgattct cctgtaccag
     1801 atgggcgaat atccttggtc actggcaaaa caagtggtag gtcctgctca ggaaccgctg
     1861 tcgaggtacc gtcctcccaa tgaatgattg ggattggctc accccagtag cgctgacgac
     1921 tgaacagcca gtcacgtagg cgataagaga ccttttcatg accgacacca gtctcctcca
     1981 gccacgccac cattttagca atggcacaag ccttatcaag accatctagg aagtcagaat
     2041 taatgtgaat accgtcctct gtgtaggcag cctcatcaac attgccccct tcaagcactg
     2101 gaataatctc aagattgaat tgctttgcaa atgcccagtc acgctcatca tgcgctggca
     2161 ctgccatgat agcacctgta ccgtagcttg caagcacata atccgcaatc cagataggca
     2221 tttctttgcc attgaccggg ttgatcgcat aggctcctgt ccagacacct gttttttcct
     2281 tggcaagatc ggtacgagca aggtcagatt tgaggctcgc ttggcgtttg tactcagcaa
     2341 cagcctgcgc ttgctctgct gtagtaatgc tatctactaa ggcgtgttct ggtgccaaaa
     2401 cagcataggt tgcaccaaac agggtatcag gtcgtgtggt aaagacggtg aagtctttat
     2461 cggtatcttt gaccttgaag gttacattag cccctgttga tttaccaatc cagttgcgct
     2521 gcatatcctt gatcgactct ggccaatcca cttcctccag atctgctagc aagcgctctg
     2581 cgtaggctgt gattttgagc atccattggc gcatgggctt acggacaact ggatagcctc
     2641 cacgctctga tgtgccatca gggagaacct cctcattcgc aatagctgtt cccagctctt
     2701 caacccagtt aacaggcacc tcagcttcat aggctaggcc tttttcatac aattttgtga
     2761 aaatccactg tgtccatttg tagtaactag gatcagttgt attgatctca cgatcccagt
     2821 catacgagaa gccaagagca ttgatctgac gtttaaagtt ggcaatgttt tctgctgtaa
     2881 actcagcagg gtcattacca gtatccatcg cgtattgctc agcaggcaga ccaaaggcat
     2941 cccagcccat tgggtggagg acattataac cctgtgcacg cttgaagcgg cttaaaatat
     3001 cagttgcagt gtaaccctca ggatgcccaa catgaagacc tgcaccggaa ggataaggaa
     3061 acatatctaa agcataaaat ttaggctttg aggcatctgt ccccgtttta aaggtatgat
     3121 tatcagccca aaaggcctgc cacttaggct caatggcttt gtgattgtaa aatgtcatgt
     3181 gaattctccc atgtaaaaag tctagtcttc ttattatagc acgatatcag acttttagga
     3241 atgggcaagc aatattgctg ccacgacgtc ggcatcacaa aaatgcatgt aaccattttc
     3301 tagctgcatg cattttttta atctatgttc agcggttttg cattgcaata tcaccagttt
     3361 ctcgattgct atttgactat ttcataacat attgccaaaa aaactatact gatgataaaa
     3421 actcgctatg agaaagtgta actgtcttca tgcgtttgtc acgacattgc taaagccctt
     3481 tagactagat agcgcgtctc tgcgacgcat aagctcaagc cttacgagcc aactcataaa
     3541 acagccaaat atccgctatc atctcacttg gttttagatc tggtctagct ctagttttaa
     3601 gctctcaaag aggtattgag cttgaccaag gagtgcttgc taagctacta aaaagcccct
     3661 tatccttgct atcagataag aagctcaata gagtttatag gaatgccaat gtccattagt
     3721 aaaatgctat aaaacaatag ttaaagggga gagaattgag aatagcttaa tttttttggc
     3781 gttttggcat gactgttact aggcctgcac ttgtcataat cgcaactgca gcagcagtga
     3841 aaaatggatt tgcagtagct tcacctgttg atggtagctg gcctgctggt tttgcggctg
     3901 gcttacttgc tttttgcttt gcaaccgagt tcgatgcctg aggagtctta gaacgaggct
     3961 gtgcctgatc cttaaacttg tcagcaagct cctgcttcaa gcgctcaatg ttagcttgaa
     4021 gatcagcatt gctacgatcc ttttgctcaa gcaggctttg aagctcctta accttagcct
     4081 caagctctgc cttgtctgcc ttaaccacat caagctcggc tgttttttca gctaattgcg
     4141 cttcaaggtc agccactcta ttattagctg ctgctacctc ttgcccaaga tttgatactc
     4201 ttgcattagc ttcagcaagt gcctgatctg ccgcagcttt ttcctttgca agcttatcaa
     4261 cattagcctt agcacctgcc agctcctctt gaagtgttgt gatgttagca ttagcagttt
     4321 caaggtcagt ctctgcttta accttgtcct gtgttaattg atcaatctca gcaagcttct
     4381 ctgtgagctc acgcttagca gagttagtca atcgacccag actatcaaca gcctgactta
     4441 aacgatctgc ttctgcttga gctactgaga gtttgttggc aagatcggca gattcactga
     4501 gagcattatc acgatctgat gttacctctt ccagtttagt gcttaattct ttagaagtaa
     4561 gtttttctct ttctatatcg gctttcaatt gagttgtttc tgctttcaaa gtagcttcag
     4621 agtcgatgcg agtctttaaa ttcgctaaaa gttttgagga aataaaatta cttcctttga
     4681 taccaataga agaattaatc tttttatcta aactagggtt gatttacaac tcttcatgtt
     4741 gtttgtttct cctttttatt tttctctttc ccagaccaaa gcacctactc cctaagggaa
     4801 ttacacgttg gcctatagct atattctacc taattttatt ggattaacaa agctcactaa
     4861 ttttacacca tgacaagttg tggctatttt aatgaaatat accgatatct atcaatagcc
     4921 gatgttccca agcttgttag ttgttttcgt ttcaaagata ctacccattc gttttcttag
     4981 ataatggtta agcttggcga ctataacggt tggcacaaat cgactaaaga aaaagatatc
     5041 agcatgctca cagcccctaa tgaccgtatc agtaataatg acgtcatagt catgctgtag
     5101 acacaaggct tctatggtta atttatcaaa aatggtaatc tcaaaaaatt caccaatgta
     5161 ttttttcaaa aagcttcccg tactgccatg acttctttct ataatcaaga gctttggttt
     5221 tttcatcaat tcacacatgg ttaaaaagaa attctcccag gctatcagca aggaataaac
     5281 caaattgttg agcaaattag tagcaagctc catatccccg tccttaaata gcctcttcac
     5341 ataatcggta aacctaaaat aaacataggt ataatgctcc ttaaagaagg ccaagtaatc
     5401 ctttttataa tcgtaaatca gaaagctttc actaatatcc tccactccta aaataacagt
     5461 ggcatgaaga tatctggcaa cctcatattt atttggcaat acaatacctg tagctccctc
     5521 catttcacta agcaaatcta tccagctcag caaggactga ggacccggaa cctcctcctt
     5581 aaccttatct acctgcaagg atttttctaa taccaaatca tcatctaaat aattggaaaa
     5641 catttctgac aagacaagct catcaagcgg tactgaaaat ttaagcacaa acaaatgcga
     5701 cagctttttc atctcctgag aatcctgtaa caactccaat gaaagactac tcagtgcttt
     5761 atgcttccca attttaaagc ctttgaggta gcgaatgaga ttaaccgcac ttaatagctt
     5821 gagttgacga aaaatcgcaa aatcaatctt aacctctatc aaagatgcca ttaattgaac
     5881 aaattgctca tggtggtttt cattaagtag agaagcaaaa ggccattcag aaaaggtata
     5941 tgcttctgaa aaatacttga tgtaaaacag tctaatattg tattcatctc caactacacg
     6001 aatgggctta gccgaaatga taatatcaaa atgctctttt aaatagagat tggttttacg
     6061 aatcaagcgc tttaaggttg acaagctaat aaaaagtgcc tctgcaagat catctaatga
     6121 cgcaaaatca tcaaaaaaca aggccgacat caactgaaga gaaggagact ctagcaaggc
     6181 tctccgataa acctccttta agccactttg atgattgtaa tgaatatgaa attgagaatc
     6241 cttgtagaac agcttgccta aatcttccat aaaaacagaa ttcgtgatac acgattgcag
     6301 cgttaaaacc gaacaatcca gcatctgaca agcatcttta taatataatg gatttttcgt
     6361 ttcacttaat aaagtaatca actcaagctc tcgccactgc tgcttggtaa agagattctc
     6421 tatagacatg gtatctagct cctaaatata ctcttcctga ttaaaaactt accacaacac
     6481 aacactattt cattaactct taatgtcggt tgtagaacag tattacatta tagcatacta
     6541 ttagccagaa ataccttaga attgtttgca aattaaccga ttacaaatag acaaaagcct
     6601 ttaaaacaca acagtcaact cattttt
//
LOCUS       DARYXW010000101         6427 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.101, whole genome shotgun sequence.
ACCESSION   DARYXW010000101 DARYXW010000000
VERSION     DARYXW010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6427
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.101"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(228..608)
                     /locus_tag="TV191_001716"
     CDS             complement(228..608)
                     /locus_tag="TV191_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HEL1508204.1"
                     /translation="MIKVFETRVTAIGSEAADMISAANMLILFDQGAPADLADFCYTI
                     DNKQVSGSISAGGQLVIDQMAYDITAVGAVVEKNLAQLGHITISFDGSTASSLPGTLH
                     VKGKGLPQVRQGSLVQIFAWLRCS"
     gene            complement(642..1634)
                     /locus_tag="TV191_001717"
     CDS             complement(642..1634)
                     /locus_tag="TV191_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002284531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HEL1508205.1"
                     /translation="MTYHSITVVKGSGGYGGPLTITPTEAKHKFIYITGGGKKPDIVD
                     KIAALTGMEAVNGFVTSIPDDEIALAIVDCGGTLRCGIYPKKGIPTINIVATGKSGPL
                     AQYITEDIYVSAVGLEQITASDAQAHVASAKESSVPKASSYDTSKKITEQRAESSFVA
                     RIGMGAGKVVAIFNQAAREAIQTLINTILPFMAFVSLLIGFIQGSGVGNWLAKLMVPL
                     AGNIWGLIIIGFICSLPFLSPLLGPGAVISQIIGTLIGVEIGKGTIPPQMALPALFAI
                     NTQNGCDFIPVALGLSEANAETVEVGVPSVLYSRFLNGVPRVVVAWIASIGLYQ"
     gene            complement(1650..2195)
                     /gene="srlA"
                     /locus_tag="TV191_001718"
     CDS             complement(1650..2195)
                     /gene="srlA"
                     /locus_tag="TV191_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677306.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HEL1508206.1"
                     /translation="MEMITRFAEGFMKLFQLGGETFVSWMTGIVPVVLMLLVAMNALI
                     GILGDQRVNQLAKISAKNPISRYMVLPFISAFMLGNPMAISMGRFMPEYYKPSYVAAQ
                     MQFCHTSNGVFPHINPGELFVWLGIASGIKTLGLSQMDLAIRYLLVGLIMNFVGGWVT
                     DFTTAYVAKQQGVTLSKMIEL"
     gene            complement(2331..2792)
                     /locus_tag="TV191_001719"
     CDS             complement(2331..2792)
                     /locus_tag="TV191_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HEL1508207.1"
                     /translation="MSFMVIFGLFVIVAYLFQLLLGLRQLKHFNAVYASLRRQGRVAI
                     GRRAGKIRAGTIVMFALDQSGKVLDARQMQGVTVAARFKPMPAYIGQDIHYFDRYNPL
                     IRRENKLLRLAIEDAREVFLRVEAGVYEDAPKYASAFDWTLQAKQLLARFK"
     gene            complement(2792..4564)
                     /locus_tag="TV191_001720"
     CDS             complement(2792..4564)
                     /locus_tag="TV191_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEL1508208.1"
                     /translation="MSNAASSIGQLNDILDGDATITQQGAFLQLQVYDYARLETILAG
                     SLRKASDFNSASKRVAYLLKRLLQSSSALVIDDLADEIGVSRSTINKDLKAAKALART
                     YSVMIQGKPNHGIQAVGTELNLRLLYVHEVYKYFEPQGLCGDSLFFLDELYQTYQLPR
                     KIQELLTKSFAITIERMRQGRYLTDPIPYYSNEVDSSAFMEELVYHIELAYQLSLSQY
                     ERQFISFPLNIQYIEDLAYQEKPLQQSIVRLYSKMIEHIKTSLLVTIDQDKLFVALHT
                     HLKLLVNRLIFHVQANDIFHGEIRYKYPLAFDMAIVAAQVLAEEFDCAIELSECSYLA
                     LYFEMMMKDAEHVTEPTVKKIAVVCTTGRGTANMICRRLSKVLGPDLLISQFSEEQFN
                     PDDNDHYFAIFTTVPLKFGQLKSPVLQITNLFDDQWLQNEWRRVHHYHQKNLATITLH
                     FARLSKGKAYTDYLTEMAELLEEKQLVDRQFGQRLLEREALQSTLFGNRIAFPHTIND
                     KETKTVLLLGLLDEPYREHDCLVEFIFLVAISKRVEAQMEADLLKIYDDIFKIASDDK
                     LQAELRSLKSQAEFIAFTKEKGVF"
     gene            complement(4858..6207)
                     /locus_tag="TV191_001721"
     CDS             complement(4858..6207)
                     /locus_tag="TV191_001721"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEL1508209.1"
                     /translation="MSHITFDYSKVLEQFAGQHEIDFLQGQVTEADQALRQGTGPGSD
                     FLGWLELPENYDKEEFARILKAAEKIKADSDVLVVIGIGGSYLGAKAAIDFLNSHFAN
                     LQTAKERKAPQILYAGNSISSSYLADLVDYVQDKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDKVKGAVKVEADANHWETFVVPDNVGGRFSVLTAVGLL
                     PIAASGADITALMEGANAARKDLSSDKISENIAYQYAVVRNILYRKGYVTEILANYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGYRNLFETVIRVDK
                     PRQNVIIPEMAEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGGVPNMFITLPEQDEF
                     TLGYTIYFFELAIALSGYLNGVNPFDQPGVEAYKKNMFALLGKPGFEELGAALNARL"
BASE COUNT         1871 a         1545 c         1291 g         1720 t
ORIGIN      
        1 ggataaatta attaaataat caactaatgt acaagttgtc tttaagctga aaagaggcta
       61 tcaacagcct ctttttttga tgatatagat aagcccaatg cttccttaga agagctcttc
      121 tgtgagatga ccttatcacc tgacattagc tgcttggctc atgcctacag ctaaaggaaa
      181 tgccctgcaa ggatagcagc acttagcctg ctggtctacg gcgtgtctca gctgcaccta
      241 agccaagcaa agatttgtac taggctgccc tgcctgacct gtggcagccc tttgcccttg
      301 acatgcagag taccgggaag agagctggct gtggagccat caaaagaaat ggttatatgc
      361 cctagctgag caagattttt ttcaacaaca gcacctactg ctgtgatgtc atatgccatt
      421 tgatcaatga ctagctgacc accagcagag atagacccag acacttgctt gttgtcaatc
      481 gtatagcaaa agtctgccaa gtctgccggt gctccctgat caaaaagaat aagcatattg
      541 gcagcactaa tcatgtctgc cgcctccgat ccaatagcgg taactcttgt ttcaaatact
      601 tttatcatac attctctctc ttcctatcat acgatagctc cttactgata caaaccaata
      661 cttgcaatcc aagcaacaac aacccgagga acaccattta aaaagcgtga ataaagcaca
      721 gatggcaccc caacctctac tgtctcagca ttagcctctg ataaaccaag cgctactgga
      781 atgaaatcac agccattttg cgtattaata gcaaaaagtg caggaagagc catttgtggt
      841 ggaatagtgc cttttccaat ctcaacacca atgagcgttc cgatgatttg actaataacc
      901 gcaccaggtc ctaacagcgg tgataaaaat ggcaacgaac agataaagcc aatgataatc
      961 aagccccaaa tattaccagc cagcggtacc atgagcttgg ctagccaatt accaacacca
     1021 gagccttgga taaaaccaat taaaagagag acaaatgcca tgaatggcaa aatcgtattg
     1081 attaaggtct ggatagcctc acgcgccgct tggttgaaga tagcaactac cttacctgct
     1141 cccataccaa tgcgggcaac aaagctgctt tctgcgcgct gctcagtaat ctttttgcta
     1201 gtatcatagc tgctagcctt tggaactgat gactccttag cactagcaac atgagcctga
     1261 gcgtcactgg ctgtgatttg ctcaagacct acagcagaca cgtaaatgtc ctcggtaatg
     1321 tactgtgcca agggaccgct tttacctgtc gccacgatat taatggttgg aatgcctttt
     1381 ttagggtaaa taccgcagcg tagggtgccg ccacaatcca caatagctag ggctatctca
     1441 tcatcaggga ttgaggtcac aaagccattg accgcctcca tacctgttag ggcagcaatt
     1501 ttatcgacaa tgtcaggctt ttttccaccg ccagtaatat agataaattt gtgcttagct
     1561 tctgttggtg taatggttag cggcccacca tagccaccgc tccccttaac aactgtaata
     1621 ctgtgataag tcatcatgct acctctcttc tataattcaa tcatcttact taatgtcaca
     1681 ccctgctgct tggccacgta ggctgtcgta aagtcagtta cccagccacc aacaaagttc
     1741 atgattaacc caaccaagag gtaacgaatc gccaagtcca tttggctcaa gcctagcgtc
     1801 ttgatacctg aggcaatacc taaccagaca aacaattctc ccggattaat gtgtggaaag
     1861 acaccgtttg acgtatgaca aaattgcatt tgagcggcaa catagcttgg cttgtaatac
     1921 tcgggcataa agcgtcccat gctgattgcc atcggattac ccagcataaa agctgaaata
     1981 aaaggcaata ccatgtagcg actgataggg tttttagcag agatttttgc caattgattg
     2041 accctttgat ctcctaaaat accaattaag gcattcattg caaccagcag catcaagacc
     2101 accggcacaa tgccagtcat ccagctgaca aaggtttcac caccaagctg gaagagcttc
     2161 ataaagcctt ccgcaaatct tgttatcatt tccataaata aactcctcat atgatgtact
     2221 tacaagcaag acaatacaaa tgtactgcct gcttgataat agctgcttga gctggactca
     2281 aaacagcttt tatgttgaca aggcaagcaa tcaatcctgc ttttggcacc ttacttgaag
     2341 cgtgccagca gctgcttggc ctgtagggtc caatcaaagg ctgaggcata ttttggtgcg
     2401 tcctcataga cccctgcctc aaccctcaag aagacctctc ttgcgtcctc aatagccaag
     2461 cgcagcaatt tattttctcg tctaatcaag ggattgtagc gatcaaaata atgaatatcc
     2521 tgaccgatat aagctggcat tggcttaaac ctggctgcca ctgtcacacc ctgcatttgc
     2581 ctagcatcta ataccttacc tgactgatcc aaggcaaaca tgacaatggt tccggccctg
     2641 attttcccgg ctctacggcc aatagcaacg cgcccctgtc gtctaagact ggcataaaca
     2701 gcattgaagt gcttaagctg tctcagacct agcaataatt gaaaaaggta agcaactatg
     2761 acaaatagtc caaaaataac cataaaactc attaaaaaac tcctttttcc ttggtaaatg
     2821 caataaactc agcttgactt tttaggctcc ttagctccgc ctgaagctta tcatcgcttg
     2881 ctattttgaa aatatcatca taaattttca agagatcagc ctccatctgc gcttcaaccc
     2941 tcttggaaat agccactaga aaaataaact ccaccagaca gtcatgctca cgataaggct
     3001 cgtctaatag acccagcagc aggacagtct ttgtttcctt gtcattaatc gtatgtggaa
     3061 aggcaatgcg attgccaaat aaggttgatt gcagggcctc acgctctagc aggcgttgac
     3121 caaactgcct gtcaaccagc tgcttttcct caagcagctc cgccatttca gtcaggtagt
     3181 cagtgtaggc cttccccttt gacagacgag caaagtgtag ggtgatggtc gccaggtttt
     3241 tctggtgata atgatgtacc ctgcgccatt cattttgcag ccactggtca tcaaacagat
     3301 ttgtgatttg gagaacagga gattttagct gaccaaactt cagcggcaca gtggtgaata
     3361 tggcaaaata gtgatcattg tcatcaggat tgaattgctc ctcagagaat tgtgagatca
     3421 acaaatcagg acctagcacc ttgctcaagc gacgacaaat catattggca gtgccacgac
     3481 ctgtcgtgca gacaacggca atttttttca ctgttggctc tgtcacatgc tcagcgtctt
     3541 tcatcatcat ttcgaaataa agggccaaat agctacactc agacaattct atggcgcagt
     3601 caaactcctc tgctaagacc tgagctgcga caatggccat atcaaaggcc aaggggtatt
     3661 tgtatctaat ttctccatga aaaatatcat tggcctgaac atgaaaaatc aaacgattca
     3721 ccaagagctt caaatgcgta tgcaaagcaa caaaaagctt gtcttggtca atagtcacca
     3781 agagactggt cttgatgtgc tcaatcattt ttgaataaag cctgacaatg ctctgttgca
     3841 gaggcttttc ttgataggct agatcctcga tgtattggat attcaaggga aagctaataa
     3901 actggcgctc gtattgactc agtgacagct gataggctag ctcaatgtga tagaccagct
     3961 cctccataaa ggcactggaa tcaacctcat tgctatagta aggaatagga tctgtcagat
     4021 acctgccctg acgcattcgc tcaatggtta tcgcaaagct cttggtcaaa agctcttgga
     4081 ttttgcgagg aagctggtag gtctgataca gctcatctag aaaaaacaag ctatcaccac
     4141 acaagccctg cggctcaaag tatttgtaaa cctcatgaac ataaagcagc cgaaggttca
     4201 actcagtgcc aacagcctgt atgccatgat tgggcttgcc ctgaatcatg accgaatagg
     4261 tcctagcaag agccttggct gcctttaggt ctttattgat cgtgctgcga ctgacgccaa
     4321 tctcatcagc caaatcatca atgactaaag ctgaggagct ttgcagtagc ctttttagaa
     4381 gataagctac ccgcttgcta gcggaattaa agtcactagc cttacgtaaa ctaccagcta
     4441 atatcgtctc taatctagca taatcataga cctgcagctg caaaaaggcg ccttgttggg
     4501 tgatggtcgc atctccatct aaaatgtcat tgagctgacc aatgctactt gcagcgtttg
     4561 acatcgtctt ttcacaaagt cacagcttag aaagctagca gaggagacaa aagcaagacc
     4621 ttatcagcta acagcagcat attaaacgaa cagctagtga tactgatcct actaagcata
     4681 gagctccaaa agcctggctt aaatagtatt caaaatagaa caagagctct caagaacaat
     4741 aacctagcgc actacttgcc ttgataagcc taaccgacct tgaaaagaag caaaaaaaag
     4801 agcctctcac gagactcttt gttatgtttt agcagactag tctagctagc tctgtcatta
     4861 caagcgtgcg ttgagcgctg ctcctagctc ttcaaagcct ggcttaccaa gaagggcaaa
     4921 catgtttttc ttgtaagcct caacacctgg ctgatcaaat ggatttaccc cattgaggta
     4981 gcctgaaagg gcaatagcaa gctcaaagaa gtagatcgta tagcctagtg taaattcgtc
     5041 ttgctctgga agcgtgataa acatatttgg cacaccaccg tctgtatggg caagaaggac
     5101 accatctgtt gcttttttgt tgacaaagtc aacgtctttg ccttgtaggt agccaaggcc
     5161 atcaagatcc tcagccattt ctgggataat cacattttga cgtggcttat ccacacgaat
     5221 cactgtctca aagaggttac ggtagccttc ttggataaat tgaccaagag aatgcaggtc
     5281 tgtcgagaaa ttagctgaag ttgggtaaat acccttttgg tcctttcctt cagactcacc
     5341 agccagttgc ttccaccatt cgctaaaata ctgcaatgat ggctcatagt ttgccaaaat
     5401 ttcagttaca tagcctttgc gatagaggat attgcgaact acagcatatt ggtaagcgat
     5461 gttttctgag attttatctg atgacaggtc cttacgagct gcatttgccc cctccatcag
     5521 cgcggtaata tcagcacccg atgctgcaat tggcaacaag cccacagctg tcagcactga
     5581 aaaacgacca ccaacattat ctggcacaac aaaggtttcc caatgatttg catcagcctc
     5641 aaccttaaca gcacccttga ccttatcagt cgttgcatag atacgcttgt tggcctcttc
     5701 ttgaccgtac tttttaacaa gtaattcttt aaagacacga aaggcgattg caggctctgt
     5761 tgttgtacca gacttagaaa tcacgttaac agagaaatct ttatcttgaa catagtccac
     5821 aagatcagca agatagcttg atgagatgga gttcccagca taaagaattt gtggtgcttt
     5881 gcgctctttt gctgtttgta ggttggcaaa atggctgttc aaaaagtcaa tcgcagcctt
     5941 agcaccaagg taagagccac caataccaat cacaacaaga acgtcactgt cagccttaat
     6001 cttctcagct gctttaagga tacgagcaaa ttcttctttg tcatagtttt caggtaactc
     6061 aagccagccc aagaaatctg atccaggtcc agtgccctga cgtagtgcct gatcagcctc
     6121 tgttacctga ccttgtaaaa agtcaatttc atgctgtccg gcaaattgct caagaacctt
     6181 tgaataatca aatgtaatat gtgacattat tttactccct taacttttaa agtttcatta
     6241 gtatcataac cttttctatt caatatttca atgtttttta tttttgggga gggtggcctg
     6301 actttaacga catgaggatc atttctgtct aaaagcagct ttgtgatgag cctagcgctt
     6361 ccctatctgc ttctactata gcttactggg gctgatccgg gtgatgtggt agcctcttgg
     6421 catagcc
//
LOCUS       DARYXW010000102         5941 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.103, whole genome shotgun sequence.
ACCESSION   DARYXW010000102 DARYXW010000000
VERSION     DARYXW010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5941)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5941)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5941
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.103"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            141..464
                     /locus_tag="TV191_001722"
     CDS             141..464
                     /locus_tag="TV191_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508210.1"
                     /translation="MKNLDHQKAELLEAVHQLGYDSLRYSIFSKERPGEWETVIEYDN
                     SQGLYVVYATMDRASYNKKLTFETFQEAKEKFLEKLRLDIQINRYYVEEGMPVNYDSP
                     LWSKN"
     gene            777..1247
                     /locus_tag="TV191_001723"
     CDS             777..1247
                     /locus_tag="TV191_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEL1508211.1"
                     /translation="MAYSKEIIAYLVRSGVAKELARDISQDVLLKMLESDLALPPEKI
                     RAWMYRVAVRKYIDRYRRDKAYLDILQRDFFHQERVVEFDHPNYEPLYTAVNELPEKY
                     RWVLSFYYFQDLSVKEMASLLHWSVSSVKVNLMRGRRCLKEKLKKAGYTYDDFN"
     gene            1231..2324
                     /locus_tag="TV191_001724"
                     /pseudo
     CDS             1231..2324
                     /locus_tag="TV191_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623137.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="anti sigma factor C-terminal domain-containing
                     protein"
     gene            complement(2618..5764)
                     /locus_tag="TV191_001725"
     CDS             complement(2618..5764)
                     /locus_tag="TV191_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508212.1"
                     /translation="MKLKKIIALACVGILTLHQLSPAIVYATTDTSDGIAATVNAGDT
                     AAPSAEAKLSQLMTDTQALFTDNSCSKLASGVTQEKIDTLKQKATDSTEPEKEQILGL
                     LDKAASLLQQFTLQGLGNGVFAQLYFYADGSYTASLVTKRGQPHSYFSTNYATITILN
                     NKKETVYSKEYAGNVSQVAQTEELELKEGYYLIINKQEPNRFYTNHNDALKQNNTNPY
                     TYVVRDGQLERIDDSNRTLRFLGLGNAEYATLRVDYNASTLTLKTKQTKPHVYFSGSY
                     EKLEVLDTENQVIYTKDFIGTQVLEAKTETIPFKVGYKIRLTGSEHHTRVKFYDDYAV
                     EAPLTLSKNQATLKLLDHSLELMRSKTGSELESEVLTLFTDESTSKLASGVTQEKIDA
                     LRKKATDSTEPEKEQILSLLDKAASLLQQFTLQGLGNGIFAQLYFYADGSYTASLVTK
                     KGQPHSYIANNYATLTILNEKKETVYAKEYVGNVSQTAKTESLTLKEGYYLVITKQEP
                     NRFYTNHNDALKQNNTNPYTYVVRNGQLERIDDSNRTLRFLGLGNAEYATLKVDYNAS
                     TLTLKTKKAKPHVYFSGTYEKLEVLDLKDKVVYTQDFIGNQALTAKTETIPFKVGYKI
                     RLTGSEHHTRVKAYDEENKAVSLSLPKNKAEIRITKGGLASVFALEAKATNTLVQAVE
                     KRLTKEKIEDFKKQDDKHKAFIDWLLKDNEAMQLYLGAGYAHSAAQGGMSSYQFKNTY
                     NLTNELEALELWFKIWDKYETSHQGIQLKMAIAVALEFNKPVGAWYNESRKIDPLERF
                     ATFAEAEQGNILFEDFYSLTVEQIRNVVNAKITDEDMKWLRQYVETNKPAMINRNDIT
                     KGYSLISYVMTNPETGVSVQSSGFYGPNPTIKEVIKYGGVCGAMSKLSSVLAQAYGVP
                     AFPIGQPGHCAYIYLNADHTYQLGYDVSGWTGCGNYNTTLPYVQIHNVYSLNIDAYNA
                     SEYERYKAEAATDKETKLNHLDAALKAEPLNYKAWNDKLALVASDQTAYQSTLNDMKS
                     ALKDYPVIINNLEKDTKQ"
BASE COUNT         1680 a         1112 c         1276 g         1873 t
ORIGIN      
        1 atttttcact ggtagacata gcaactccac aaaaaggaat gattgatctt gtctttggct
       61 ctggtggagg tatccaaata aagttaggaa cttctgtaag ttggtatgaa aaattgggtt
      121 taattaagga gataaagtag atgaaaaatt tagatcatca aaaggcagaa ctattagaag
      181 cagtccatca attaggttat gatagtctaa ggtattccat tttttctaaa gagagaccag
      241 gagaatggga aactgtcatt gaatatgata atagtcaagg cttatatgtt gtgtatgcaa
      301 ctatggatag agctagttat aataagaaat taacatttga aacatttcaa gaggctaaag
      361 aaaaatttct tgaaaaactt cggttagata tccaaatcaa caggtactat gtggaagagg
      421 gcatgcctgt aaattacgat tctcctttgt ggtcaaaaaa ttaatacaag taaaggagaa
      481 tatacatggc atgtagtcaa ttagagtggg aagataaatg aaataatggt cctaggaaat
      541 gtcccgactg gaaactatct tatgaactct tttatggaaa agtgttgcac ttaatttgaa
      601 ttttgtcata taaaaaagcc ctataatctc catggtggac ttacccacta cagaaatgat
      661 agagctaaaa atctccattt ggggattttt ttgtaaccaa atgaagcagt cgttcgttat
      721 ataggtgaag aagggagggg agaattatca ggctagatgc ttatgaaaga gagctagtgg
      781 cttattctaa ggaaattatt gcctacctag tgagatcagg tgttgctaag gagctagcgc
      841 gtgatattag tcaagacgtt ttgttaaaaa tgcttgagag tgaccttgct ctgcctcctg
      901 aaaaaatacg tgcctggatg tatcgggttg ctgttagaaa atacattgac cgatataggc
      961 gggataaggc ttacttggat attctccaaa gggatttttt tcatcaagaa agggttgttg
     1021 aatttgacca ccccaattat gagccgcttt atacagcagt caatgaattg ccagaaaaat
     1081 accgctgggt cttgtcgttt tattactttc aggacctatc agtcaaggaa atggcgtctc
     1141 tgctccattg gtcagttagc agcgtcaagg tcaacttgat gcggggaaga cgatgcctta
     1201 aagaaaaact aaagaaagca ggttatacct atgacgattt caactgattt tgaagccatt
     1261 gctaagcgcc ataaaaggag gctgaccctt aaatatgtag tgctgagtgc tggcttagcc
     1321 ttagtagctc ttgtactggg ctatatggga ttaaatcgat tgacaagcat gaacggtcag
     1381 tatttaatgg cttattacaa caatcgtata caaattgctt atcccaatat tgatgttaat
     1441 agcttctttt acaatgccaa ttcgcagttt actggtgagc ttcattctga gcggaccaag
     1501 gatattgctg ggatttcggt accgtttgag ccctatagag ctccttattc cttgccttta
     1561 cccagagaga gatggactat accaatgaat accttgtttc aggtgatgat ggacggtcaa
     1621 cctacacaag aggtacacat tataaaatgc ctcgcttctt caacactaag gccaagatca
     1681 cagaaagcaa ctatgacaag ccaacgcagg acctagactt tattgctgac atgtcaggac
     1741 aggcgattga ggtagccatt acctttgata agccttattt attatcggac atagtcaagc
     1801 tggttccaga ccagctaaag ctgaattgga tctggattgg cacagaaagc agctatgaca
     1861 cctcagggct tttccctgct aatttatatg gctttaagcc aaactggaag gctaatatga
     1921 cgtacaagga gcaaaagcag ttagataaaa aaataaacga tatcctaaaa aaggacagcg
     1981 aggctgattt gtctaagctt aatgctgctt acgataagcc agtcagtcca acggtggctc
     2041 tgcaaaattc ctatgatacc ttcaggcact atctacaaga ggcagctgac aatcattgga
     2101 ttaatagtac ctatggcggc gctaatggat ctcatttaag tgagcaggag gatgtggcct
     2161 tatttctaaa aaacaatcgc aatgtcaaaa cagctaagtt tgctggcatt attttaaccg
     2221 gcaaggctga gcagtttgcc tccttaaaaa cagctgattg gatttatgcc tcaaatattg
     2281 gtcagtctgt tgccattcag ccctatcatc agctaaccaa gtaaataaaa agcttgtgct
     2341 gctaatcaag cgcatcaggc aaaggataaa aagcctaaaa gagattagat taagtaaatc
     2401 gatgcttaaa aaagctccag cttaggtcaa aagacgtcaa aaggctcttg gaggtcagtg
     2461 tttgatcact gcttctgggg ctttttgctt tgctgcaatc aaaaaagctt gaagcagctc
     2521 tctcaattga gcatgtcctt caagctgaga ctcttatatt ttatagtatt tgtaagtata
     2581 gttttagcta gccttctttt aagcccaagg gcttagctta ctgtttagta tctttttcta
     2641 aattattgat aataactgga taatccttca atgcagactt catgtcattt agagtgcttt
     2701 gatatgctgt ttggtctgag gctaccaatg ctagcttgtc attccatgct ttatagttta
     2761 atggctctgc ctttagagca gcatctaaat gattaagctt agtctccttg tcagtagctg
     2821 cttcagcctt atatcgttca tattctgagg cattataagc gtctatatta agagagtaga
     2881 cgttatgaat ttggacataa ggaagtgttg tgttgtagtt accacagcct gtccagcctg
     2941 agacatcata gccgagctga taggtatggt cagcatttaa gtagatataa gcacagtgac
     3001 ctggttgtcc aataggaaag gctggtacac cataagcctg tgctagcaca ctacttaatt
     3061 tagacatagc accgcagaca ccaccatatt tgatgacttc cttgatggtt ggatttggtc
     3121 cgtaaaagcc agagctttgg acgctcacac ctgtttctgg gttggtcatg acatagctga
     3181 tcagtgaata gcccttagta atatcattac ggttaatcat agcaggctta ttggtttcaa
     3241 cgtattgtct taaccatttc atgtcctcat cagtaatttt agcattgacg acatttcgga
     3301 tttgctcaac agttaagctg taaaaatctt caaataggat attgccctgc tcagcctctg
     3361 caaaggttgc aaatctttca agtggatcaa tcttgcggct ttcattgtac caagcaccta
     3421 caggcttgtt aaattccaag gcaaccgcaa tggccatttt gagctgaata ccttgatgtg
     3481 aggtttcgta tttatcccaa atcttaaacc acaattccaa tgcttctagc tcattggtga
     3541 ggttataggt gtttttgaat tggtatgatg acatgccacc ctgtgctgca gaatgggcat
     3601 agcctgcacc aagatataat tgcattgctt cattatcttt gagcaaccaa tcaataaagg
     3661 ctttatgctt gtcgtcttgc ttcttgaagt cctcgatttt ttccttggtt agtctttttt
     3721 caacggcttg tacgagtgta ttagtagctt tagcctctag tgcaaataca gaagccaaac
     3781 cacccttggt gattcgaatc tctgccttat ttttagggag gctaagagaa acagccttgt
     3841 tttcttcatc ataggctttg actctagtat ggtgctcact accagttagg cggatcttgt
     3901 agcccacctt gaagggaata gtctctgttt tggctgttag agcttggttt ccaataaagt
     3961 cttgtgtgta gacaaccttg tcttttaggt ctaagacctc aagcttttcg taagtcccac
     4021 tgaagtaaac atgtggctta gcctttttgg ttttgagagt taaggtagag gcattgtagt
     4081 caacctttaa ggttgcgtat tctgcattgc ctaagccaag gaagcgcagc gttctattac
     4141 tatcatcaat acgctcaagc tgcccgtttc tcaccacata agtgtaaggg ttggtattgt
     4201 tttgctttag agcgtcattg tggttagtgt agaagcggtt aggctcctgc ttagtgatga
     4261 ctaggtaata gccttccttg agagtaaggc tttctgtttt agctgtttgg gaaacattac
     4321 ccacgtattc cttagcataa acggtttctt ttttctcatt gagaatggtt agggtagcgt
     4381 aattgttagc gatgtaagag tgaggctgtc cttttttagt gactaagctt gcagtgtaac
     4441 tgccgtcagc atagaagtag agctgagcaa atataccatt tcctagccct tgtagagtaa
     4501 attgctgtag caggctagct gccttatcaa gtaaacttag gatttgctct ttttcaggct
     4561 ctgttgagtc agtcgccttt ttcctaagag catctatttt ttcttgtgtg acaccacttg
     4621 ctagcttact tgtagactca tctgtaaata gagtcagtac ctcagactca agctctgagc
     4681 ctgttttaga cctcattagc tctagtgagt ggtcaagaag ctttaaggtt gcttgatttt
     4741 tagagagtgt taatggcgct tctaccgcat aatcatcgta gaatttcact ctggtatggt
     4801 gctcactacc tgtcaagcgg atcttgtagc ctactttaaa aggaatagtc tctgttttag
     4861 cttcgaggac ttgagttcca ataaagtcct ttgtgtagat tacttgattt tctgtatcca
     4921 gcacctcaag cttttcataa gatccactga agtaaacatg tggcttggtc tgcttggttt
     4981 tgagggttag ggtagaggca ttgtaatcaa cccttaaggt tgcatactct gcattgccta
     5041 agccaaggaa gcgcagcgtt ctattactat catcaatacg ctcaagctgc ccatctctca
     5101 ccacataagt ataagggttg gtattgtttt gctttagagc gtcattatgg ttagtgtaga
     5161 agcggttagg ctcctgttta ttgatgatga ggtaatagcc ttcttttagc tcaagctctt
     5221 ctgtttgtgc tacctgagaa acattgccgg cgtattcttt tgaatagacg gtttccttct
     5281 tgttattaag aatggttatc gtagcgtaat tagtagagaa ataagagtga ggctggcccc
     5341 ttttagtgac caaacttgca gtgtagctgc catcagcata gaagtaaagt tgagcaaaga
     5401 caccattgcc taacccttgt agggtaaact gctgtaatag gctagctgcc ttatctagta
     5461 gacctaggat ttgctctttt tcaggctctg ttgagtcagt cgccttttgc tttaaggtat
     5521 ctattttttc ttgtgtgaca ccacttgcca gcttactgca ggagttatct gtaaataagg
     5581 cttgggtatc agtcatcagt tgtgatagct tagcctcggc agaaggagca gctgtatcac
     5641 ctgcattaac tgtagcggct attccatcag aagtatcagt agttgcataa acaattgctg
     5701 gagagagctg atgtaatgtt aatattccaa cacatgctag tgctattatt ttctttagtt
     5761 tcatcgttat aaagtccttt tacaataaaa taaagtgatt caaaactctg ggaaaagaat
     5821 agctagcctt aaaactatac tcgcaaatac tataaaatag aaagactatt taccctcctt
     5881 agctcttgat gctgtggtga tgatattgtt acggtgctaa aaatcctatc cctccttttt
     5941 g
//
LOCUS       DARYXW010000103         5715 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.104, whole genome shotgun sequence.
ACCESSION   DARYXW010000103 DARYXW010000000
VERSION     DARYXW010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5715)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5715)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5715
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.104"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(<1..653)
                     /locus_tag="TV191_001726"
     CDS             complement(<1..653)
                     /locus_tag="TV191_001726"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679404.1"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="HEL1508213.1"
                     /translation="MKKQSFTHSRKPKFGMRKLSIGLASCMLGMMFLTTGHVSGEVVE
                     VWPNGQNPNGKIEILSQTEHSEHLQKLRDIEDFQAQKQADHVRYTKWLDGVTVDEHEF
                     RKIKEYDTEYYVTPLLSGKGYYDINKDFNQDSDKCAAAVAANMFHYWFDRNRDSINRF
                     LSQSPGENGVIKLENEKTIEVSKFLETYRSDGDYLDKSPFFDLISNSFKGPVWANKL"
     gene            complement(968..1777)
                     /locus_tag="TV191_001727"
     CDS             complement(968..1777)
                     /locus_tag="TV191_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEL1508214.1"
                     /translation="MKKSVIFWSVILVAGCLIVLYPTLSNYWNAQHQSQLIADYVSST
                     QALRHKDSQLMLEAANQYNQQLKANHDPDLTLTDSEAEAYQQQLDLTNTGIMAYIDIP
                     KVHERLPIYHGTDEEILQVAIGHLAGTSLPVGGKGTHAVISGHRGLPSAKLFTNIDKL
                     RINDTFTITSLNRTMTYQVDKIATVLPDDVSLLRIEEGKDLVTLVTCTPYGVNTHRLL
                     VRGHRIKTATPTAARGSQKPSRLILWLLLISALGLSLVLIGTWRWRRRSKA"
     gene            complement(1858..3300)
                     /locus_tag="TV191_001728"
     CDS             complement(1858..3300)
                     /locus_tag="TV191_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HEL1508215.1"
                     /translation="MKTIKLILTSLLVTFLTMLSGKAFADTASYTITVEGATAGHTYE
                     AYQIFKGDLFDSTLSNITWGGGVTPFEFDGSKDAAKIAEGLKEANAAAFAKEAGKHLT
                     ATIAGTGTHAITVNEAGYYLIKDKNDSQTGKHDAYTSFVLKVVKNTSFKPKSAIPTVL
                     KKVKDRNDKTGLETGWQDSADYDKNDKVPFQLTATLPSNYDAFQEYYLEFVDTLSKGL
                     SYNKDAKVYVVNGDTRQDITNSFTVSEDGSSFKINNLKAVQGVTITATSKIVVEYTAT
                     LNDQAAIGKKGNPNEVALKYSNDPNALGKGEESPKGETPKDKVIVFTYKTIINKVDQD
                     QKALKGAGFTLYKLVKGDNGEEKYQIVQEIKAGDTTSFEFVGLDAGDYKLSETTTPGG
                     YNTIADVMFSIVAQHETESDDPQLTSLTVDKATGFTADTEAGTVSATIVNKKGSILPS
                     TGSIGTTMLYVFGVMLMTISTLFIFRQKQQ"
     gene            complement(3324..5297)
                     /locus_tag="TV191_001729"
     CDS             complement(3324..5297)
                     /locus_tag="TV191_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cna B-type domain-containing protein"
                     /protein_id="HEL1508216.1"
                     /translation="MKQLTKIVSVVLLLVFTLSASLHKVRATNLSDNITSLTVASSSL
                     RDGERTTVKVAFDDKKQKIKAGDTIEVTWPTSGNVYIQGFNKTIPLNIRGVDVGTLEV
                     TLDKAVFTFNQNIETMHDVSGWGEFDITVRNVTQTTAETSGTTTVKVGNRTATITVTK
                     PEAGTGTSSFYYKTGDMQPNDTERVRWFLLINNNKEWVANTVTVEDDIQGGQTLDMSS
                     FDITVSGYRNERFVGENALTEFHTTFPNSVITATDNHISVRLDQYDASQNTVNIAYKT
                     KITDFDQKEFANNSKIWYQILYKDQVSGQESNHQVANINANGGVDGSRYTSFTVKKIW
                     NDKENQDGKRPKTITVQLYANDQKVNDKTIELSDTNSWQASFGKLDKYDSQNQKITYS
                     VKEVMVPVGYQSQVEGDSGVGFTITNTYTPEVISITGQKTWDDRENQDGKRPKEITVR
                     LLANDAATDKVATASEQTGWKYTFTNLPKYKDGKQITYTIQEDPVADYTTTIQGFDIT
                     NHHEVALTSLKVIKVWNDKDDYYHKRPKEITILLKADGKVIREHQMTPDQQGKWEYTF
                     DQLPVYQAGKKISYSIEEKQVAGYQAPVYEVDEGLKQVTVTNTLNPSYKLPDTGGQGV
                     KWYLLIGGGFIIVAILVLISLYQKHKRHNMSKP"
BASE COUNT         1509 a         1232 c         1106 g         1868 t
ORIGIN      
        1 aatagcttat ttgcccaaac aggaccttta aagctgttac tgataaggtc aaaaaacgga
       61 cttttatcaa gataatcacc atcactacgg taagtttcta aaaattttga tacttctatt
      121 gttttttcat tttcaagttt aataacacca ttttcacctg gactttgact taagaaacga
      181 ttaatactgt ctctatttct atcaaaccaa taatggaaca tattagccgc tacagcggca
      241 gcacatttat cactatcttg attgaaatct ttattgatat catagtaacc tttaccactt
      301 aaaagaggtg ttacataata ttctgtgtca tattccttga tttttctgaa ttcatgctca
      361 tcaacagtta ccccatctaa ccatttagtg taacgaacat gatcagcttg cttttgagct
      421 tggaaatctt caatatcgcg taatttctgt aaatgctcag agtgctcagt ttgacttaga
      481 atttctattt taccattagg attttgccca ttaggccaaa cttcaactac ctcaccagaa
      541 acatgtcctg ttgttaggaa catcattcct agcatacatg aggcaaggcc aatagataat
      601 tttctcatac cgaatttagg tttacgtgag tgtgtgaatg attgtttttt catcatgcta
      661 tcctttctta ttataaaacg ttttcaaaaa caacaaatta aataaatatc taatattttg
      721 tcgttaactc tcctcctttt atcattttat taggttttat aagtcaattt tatcatgtta
      781 tgctcagatg tcacttttga aggctccaaa tgctcgctct tttaaagcgt tttcggtcac
      841 taagaaaaaa aaacgatttc tgtgttttta atcatagtcg caatttagca ctaaaaaatc
      901 ccctgatagg tcctcagtaa cctatcaagg gttgatgatt tgacttagtt gcttctggaa
      961 agcctgctca tgctttagac ctcctacgcc agcgccaagt gcctattagt acgagagata
     1021 gccctaatgc actgattagc aagagccaga ggattagcct actaggcttt tgagatcctc
     1081 ttgcagcggt tggtgtcgct gttttgatac gatgccctct gaccaagagc cgatgcgtgt
     1141 tgacaccgta gggggtacag gtgaccaagg ttaccagatc cttcccctcc tctatcctta
     1201 agaggctgac atcatcaggc aaaacggtag caatcttatc cacctgatag gtcatagtcc
     1261 tattaagact ggtgatggta aaggtatcgt taatcctcag cttatcaata ttggtaaata
     1321 gcttggcaga gggtaaccct cgatgtcctg agatgacagc atgtgttccc ttgccaccta
     1381 caggcaaaga ggtgcctgca agatgaccga tagccacctg taggatctcc tcatcggtgc
     1441 catgataaat cggcagccgc tcatgcacct ttggaatatc tatgtaggcc atgatacctg
     1501 tatttgtcag atccagctgc tgctgatagg cttctgcctc actatcggtc aaggttaaat
     1561 caggatcatg gttagctttt agctgctgat tgtactgatt ggctgcttct agcatgagct
     1621 gactatcctt atgtctcaaa gcttgcgtgc ttgagacata gtcagcgatg agctgtgatt
     1681 ggtgctgtgc attccaatag ttactaaggg tggggtaaag gacaatcaga cagcctgcca
     1741 ccaaaatcac actccaaaaa atgacacttt tcttcattct atagcctcta tcaaaaaaag
     1801 aggtgaatag gtcttggtaa gacgtctatc cacttctttt tacctactca cacgatctta
     1861 ttgctgtttc tgacgaaaga taaacagcgt tgatattgtc attagcatta ctccaaacac
     1921 atagagcatg gttgttccga tacttcctgt cgaagggagg atagaccctt ttttattaac
     1981 aatagttgcg gatacggtac cagcttctgt atcagcagtg aagccagttg ctttgtcaac
     2041 ggttaggcta gtcaactgag gatcgtctga ctcggtttca tgctgcgcta caatgctgaa
     2101 catgacatct gcaatagtgt tgtaaccgcc aggtgttgtt gtttcgctga gcttgtaatc
     2161 accagcgtca agtccaacaa actcaaagct agttgtatcc cctgctttaa tttcttggac
     2221 tatttgatat ttttcctcgc cattatcacc tttgaccagc ttataaaggg taaagcctgc
     2281 accttttagg gctttttgat cttgatcaac cttattgatg atagttttat aggtgaaaac
     2341 gataaccttg tcttttggtg tctccccttt tggagactcc tctccttttc caagagcgtt
     2401 tggatcgttt gagtatttca aagcaacttc gtttggattt ccttttttgc cgatggccgc
     2461 ttggtcattg agggtagcag tgtattcgac aacgatctta ctggtagctg ttattgttac
     2521 tccctgaaca gcctttaggt tattgatttt aaaagatgaa ccatcttcac taactgtaaa
     2581 tgaattagta atatcttgac gagtatctcc attaaccaca tagaccttgg cgtctttgtt
     2641 gtagcttagc ccttttgata aggtatctac aaattcaagg tagtattctt gaaaggcatc
     2701 gtaatttgac ggtagggttg cggttagctg gaatggcacc ttgtcatttt tgtcatagtc
     2761 agctgaatct tgccagcctg tctcaagacc tgtcttgtca ttacggtcct tgaccttttt
     2821 aaggactgtt gggatagcag attttggttt gaagctggta tttttaacaa ccttcaggac
     2881 aaatgaggtg taggcgtcat gcttgcctgt ttgagaatca tttttgtcct tgatgaggta
     2941 gtagccagcc tcgttaacgg tgattgcatg tgttcctgtt cctgcaatgg ttgctgtcaa
     3001 gtgcttacct gcttccttgg caaaggcagc tgcatttgct tccttcaatc cctctgcaat
     3061 cttagcagcg tcttttgaac catcaaattc aaaaggtgta acaccacctc cccatgtgat
     3121 gtttgatagg gtactgtcaa acaagtcacc cttgaaaatc tgataagcct cataggtgtg
     3181 acctgctgta gctccctcaa cagtgatggt atagcttgct gtatcagcaa atgcctttcc
     3241 tgacagcatt gttaggaagg tgacaagcaa gctcgtcaag attaatttga ttgttttcat
     3301 agctctctct cctctattac atgttatggt tttgacatgt tatggcgctt gtgtttttga
     3361 taaaggctga tcagtacaag gattgcgacg atgataaaac cgccaccgat taacaggtac
     3421 catttcactc cttgtcctcc ggtgtcaggc agcttgtagc ttgggttaag ggtgttggtt
     3481 acagtgacct gcttcaagcc ttcatcaacc tcatagacag gggcttgata gccagcaacc
     3541 tgtttttcct caatgctgta gctgattttc ttgcctgcct gatagaccgg cagctggtca
     3601 aaggtgtatt cccattttcc ttgctgatcc ggtgtcatct gatgttcacg aatcaccttg
     3661 ccatctgcct ttagcaaaat ggtaatctcc ttgggacgtt tatggtaata atcgtcctta
     3721 tcattccaaa ccttgatgac ctttaggctg gtcaaggcta cctcatgatg attggtaata
     3781 tcaaatccct gaatggttgt ggtgtaatct gccacagggt cctcttggat cgtgtaggtg
     3841 atctgtttac catctttgta tttcggtaga ttggtaaatg tatacttcca gccggtttgc
     3901 tctgaagcag ttgctacctt gtcagttgca gcgtcatttg ccaataaacg aaccgtaatc
     3961 tccttaggac gtttaccgtc ttggttttcc ctgtcgtccc aagttttttg accggtaatg
     4021 ctaatgacct ctggtgtata ggtgttggta atggtaaatc ctactccact atccccctca
     4081 acctgcgatt ggtagccaac aggaaccatc acttccttga cactgtaggt aattttttgg
     4141 ttctgactgt catacttatc cagcttacca aaacttgctt gccagctatt agtatcactc
     4201 aattcaatgg tcttatcatt aactttctga tcattggcgt aaagctgaac agtaatagtc
     4261 tttggacgct taccgtcttg attttccttg tcattccaaa ttttcttgac agtaaagctg
     4321 gtatagcgac tgccatcaac cccgccgtta gcattgatat tggctacttg gtggtttgac
     4381 tcttgacccg atacctgatc cttgtataaa atctggtacc agattttact gttgttggca
     4441 aattcttttt ggtcaaagtc cgttatcttt gtcttataag caatgttgac agtgttttgt
     4501 gaggcatcat attgatctaa ccgcacacta atgtgattat ctgttgccgt aatgacagaa
     4561 tttggaaatg ttgtatgaaa ctctgtcaga gcgttttccc caacgaagcg ctcgttacga
     4621 taaccagata cggtgatgtc aaagctgctc atatccaagg tttgaccacc ttgaatatcg
     4681 tcttcgactg taacagtatt ggccacccat tccttgttgt tgttaatcag caggaaccat
     4741 ctcacacgct cagtatcatt gggctgcata tcaccagtct tataataaaa tgagctggta
     4801 ccagtgcctg cctcaggctt agtaacagtg atagtagcag tgcgattgcc tacctttact
     4861 gtggtcgttc ctgatgtttc agcggtggtt tgtgtcacat ttctaacagt aatatcaaac
     4921 tctccccaac cagagacatc atgcattgtt tcaatatttt gattgaatgt gaaaacagcc
     4981 ttgtctagcg tgacctccaa ggtaccaaca tctacccctc taatattaag cggtatggtt
     5041 ttattaaagc cctgaatgta gacattacca cttgtaggcc aggtgacctc tatcgtatcc
     5101 cctgccttga ttttctgttt tttgtcatca aacgcaacct ttaccgtcgt tctctctcca
     5161 tctcggagtg atgaagaagc aaccgtcaat gatgtgatgt tgtcactaag attagttgcc
     5221 cgaaccttgt gcaggctagc actaagggta aagaccagca acaagaccac actaacgatc
     5281 tttgtcagtt gtttcaaaca aaatcctcct tttacattat tgatttgcaa aatttaattt
     5341 tacaaatcac gttcatcatt gtataatgtt agcaaaaaat attatgtaca aaattaacat
     5401 taatgttcaa ttttaaggag ttaatgatac aatggataaa aataaacaaa cttgtaaaaa
     5461 aataattaaa agctactgcc gactactaca atacaaggat aaggacagta ttactgtatc
     5521 agatattagc aaggcttcta atatcagtcg aacaaccttt taacattatt tcaactctaa
     5581 gaaggactta gatagggaaa tgatcggcgt ttacctagat gatatcacct ctatcattta
     5641 ccaatcccca tcacttgata caactattac cttaaaaatc ctaaactacc tctctgacaa
     5701 tcaggaggtc atgca
//
LOCUS       DARYXW010000104         5628 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.105, whole genome shotgun sequence.
ACCESSION   DARYXW010000104 DARYXW010000000
VERSION     DARYXW010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5628)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5628)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5628
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.105"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(484..2061)
                     /gene="cls"
                     /locus_tag="TV191_001730"
     CDS             complement(484..2061)
                     /gene="cls"
                     /locus_tag="TV191_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEL1508217.1"
                     /translation="MTIKKNKKVRYLLHKGKKGLLRGIFSRTTIIAALIVLQIFFLCQ
                     SYAWMEQYRVLIAIIERIFSISIVLYLVNSDMDAISRVTWLILIMIAPLLGSLFLIYT
                     KLDWGYRDLKQRINHLVDLSSPYLRDDDAILQALKGHTSTTYHLVQYLERSRGNFPIY
                     RKTQATYFPIGEAFFEGLKTQLLLAKSYIFLEFFIIAEGQMWGEILGILEKKVQEGVE
                     VRVLFDGMLELSTLSADYAARLERIGIKAKSFLPISPFISTYYNYRDHRKIVVIDGEV
                     AFTGGINLADEYINEVKRFGHWKDAGLMLKGEAVDSFLIMFLQMWSITEKRLIVEPYL
                     SQHTEEVASDGYVIPYADSPLDTDKIGRNVYIDILNHAKEYVYIMTPYLILDSETEHA
                     LRFAAERGVDIRIIMPGKPDKAVPYALAKTYYKGLITSGVKIYEYSPGFVHSKVFISD
                     DSKAVVGTINLDYRSLYHHFECATYLYRSSVIADIVQDFKETQASSKLVTESQLRQRP
                     WYQKLVGLLVKTIAPLL"
     gene            complement(2277..5617)
                     /locus_tag="TV191_001731"
                     /pseudo
     CDS             complement(2277..5617)
                     /locus_tag="TV191_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677995.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
BASE COUNT         1609 a         1259 c         1066 g         1694 t
ORIGIN      
        1 tgacagagtg tttcctgaat ttttatattt ttcctctata aacttttctt gaaaaatttc
       61 ttttctgcaa ctatcgctat ggctttccta tttttcagaa caagttttcg catttcagaa
      121 atatcttgga aattttttct tcatgcgttt gtcgtagcta gaagcttatg gtatgacagt
      181 caatagataa gtttttcaca tcagtgctat tgttccatga taacataccc ccttagaaaa
      241 ggcagttatg ctatggatac gatgagactc acacctaaca cagtgagatg actaaacatc
      301 acaacaaaaa aagctgagag aaactctcag ctctcagggg cattcgtatc acgaatgtga
      361 taaaaaggtt cacacaaatt atcaaagtcg gctcctgcct taatgacctc cccagcacaa
      421 ctgtgattta aaaatcacaa tcgactcatc gcataggcct attatagcaa acatatcatc
      481 tctttacaag aggggggcta ttgttttaac caataaacca acgagctttt gataccaagg
      541 cctttgcctt agctgacttt ctgtgactag cttagagctt gcctgggttt ctttgaaatc
      601 ctgaacaatg tctgcaataa cagaggaacg gtaaaggtag gtggcgcatt caaaatgatg
      661 atagaggctg cgataatcca gattaatggt tccaacgact gccttagaat catctgaaat
      721 aaagacctta gaatgcacaa atcccggact atattcgtag attttaactc ctgaggtgat
      781 caagccttta tagtaggttt tagcaagggc ataaggaaca gccttgtcag gcttacctgg
      841 cataataatc cgaatatcca cccctcgctc tgctgcaaat ctgagggcat gctctgtttc
      901 gctatccaaa atcaggtatg gagtcatgat ataaacatat tccttagcgt gattcaagat
      961 atcaatatag acatttctgc caattttgtc agtatcaagt ggtgagtctg cataaggaat
     1021 gacatagcca tctgaggcga cctcctctgt atgctgggac agataaggct ccacgatcag
     1081 ccttttttcg gtaattgacc acatttgtaa aaacatgatc aaaaagctat caacagcctc
     1141 accctttagc ataagacctg cgtccttcca atgcccaaag cgtttgacct cattaatgta
     1201 ctcatcagct aggttaatac cgcctgtaaa ggccacctct ccatcaatca ccacaatttt
     1261 acgatgatcc cgataattgt agtaggttga aataaaaggc gagatcggca aaaaagactt
     1321 tgctttgata ccaatgcgtt caagtctggc agcataatcc gctgataagg tcgacagctc
     1381 tagcatgcca tcaaaaagaa cgcgaacctc tactccctct tgcaccttct tttctaaaat
     1441 tcctaaaatt tctccccaca tctgcccctc tgcaatgata aaaaattcta gaaaaatata
     1501 ggacttagcc aataaaagct gagtttttaa accttcaaaa aaggcttctc cgatgggaaa
     1561 gtaggtggct tgagtcttgc gataaatggg aaaattccca cgactacgct ctaaatactg
     1621 aacgaggtga taggtcgttg aggtatgccc cttcaacgcc tgtaaaatag cgtcatcatc
     1681 tctcaagtaa ggagaggaca aatcaactaa atggttaatt cgctgcttta ggtcacgata
     1741 accccagtct aatttagtgt aaataagaaa taaagagcct agtaaagggg ctatcataat
     1801 gagaatcagc caggtcaccc ttgaaatagc gtccatatcg ctattcacca agtacaagac
     1861 aattgaaatc gaaaaaatac gctcaataat agcaattaaa acacgatact gctccatcca
     1921 agcataggat tggcataaaa agaagatttg cagaacgatc aaagcagcaa taatggttgt
     1981 tctgctgaaa atccccctca gcaagccttt tttcccttta tggagcaggt atcttacttt
     2041 tttattcttt ttgatagtca accctccagc tttatttttt cttattatat cataaaactg
     2101 gaggtcatga tttaagtcgc tgctaaaagt ttcagcaatt ggtgcaagca ttaaaaaaag
     2161 acctcaatac ttcttttaca acttgtaatc ctcacaaaac ctactgcttt aacaaccaaa
     2221 aaaagattga aggagacatg cttccccttc aatccaagtc tcatcaggtg atgagattaa
     2281 ttatctgatt tctttttaaa taagcctaga gataggctag ctagtagcat acctaagcct
     2341 gctaataacg atgagcccta tgcctgctct gaggttttag gaagctcatg gctatgtgct
     2401 ggagccattg gtttgctgct atctggtgtc atggctagtg actgctgatc tgctttgcta
     2461 ttatcagaag actgatcttg atcagtagaa ccattgccct taggctgctg ctctggcatt
     2521 ggtgtctcag gctgtttgtc gtctttaatc tctggttcct tttggtttaa aaggtctgta
     2581 agagcaatcg cgttaaagtt gccaaattca tcttcaacaa ttaatgtcaa ggcagcaata
     2641 ttaacctcta cctcctcacc tgacagctct gacatcaccg ttgctggaat gctaaatgag
     2701 ccgtcctcag ccattgggaa gtagttcacc acaatatctg cttcctctcc ttctccaatc
     2761 tcgacaatat ggccaacctg aatacggtag gctgagaatt tagcagtgtc gatcttaagt
     2821 gttctggtag attcgtcata ggaagctgat tttggtagct ctggtaggct tgttttcact
     2881 tgaaccttaa agtcttgctt ttgagcctca gcaccatctg ctacaggagt ataccaaacg
     2941 cgataggtat agctaccatc tgctacaggc tgatcattgg cgtcttttcc actccatttt
     3001 gtatgctcaa agcgatacgg taacacaaca ccctcttgat agtatttctg ggctgaagaa
     3061 acaccacttt cccaaacgat ttgtccattg tgatcaagaa cctgagcttt aatatcctta
     3121 acgcttctta ggaatacccc ttggaagaga ataaaatcct tattaccatc atcatttgga
     3181 gaaatcaaga aggttctatc tgcctctttt gctattaaat ccttttgatc agctgactcc
     3241 tgtgttccta aaataatata tctttctgcc tcagggccta actcattgac cgttccattt
     3301 tttgtatcct gtgccaagaa atatgggctg acctgaccaa tcaaagcagt tagcttgctg
     3361 aatttctctg gtaatatgta tttacctgtt tcaggatctt gctcaagctt ttgataaaag
     3421 gcaccctgct caagcgtctc ataaatagga gtatctaagg ctggcaagtt agcaaaatca
     3481 cccctaaagc cactaaatgg aatactcatc aattcttcct tagtgtctaa attgtctgtg
     3541 aaacggacaa agccttcaag gaagtagcca tttggcattg cttttaacaa ttcagcagcg
     3601 taagccttag cgtcaacaga aacttgaata tgctgctggt cctcggtgat attaatttcc
     3661 tgccactctg aatcctttaa tgcttttggc tgcaaggtga agtgaccatc tttagtttga
     3721 tcagtgatta ggttgacttg gaaataaagc tttttaggcc cttgattttt cgatagggca
     3781 ttaacattta gattaatgac aaattcatct gcaatgttcc ccagattgat tttagggttt
     3841 tgcttctgat cagtaaggta atagctggct gctagtgcct tttgaccatc tacctcacca
     3901 gcaccctgct ggcgtggaga aatataagcc ttgttttctg tgctataaag tgttcttgct
     3961 gagctcatca acacagctct aacaagctga gaaagctcct tatcagaaag ctctgggaat
     4021 ttctctttgt aagctttatg tagcatggcc acaagccctg acaccatagg tgttgacatg
     4081 cttgtaccag tcttgtaatc atattggtta ccatgaactg cagagtagac attgacacca
     4141 ggtgctgaaa tatctggctt gatacgacct tctgctgtca caccccagct ggattggctg
     4201 ataacgcggc caccagcatt gctaagcatt ttctcatagg ccttattaaa tctaaagctt
     4261 tgaccttcct taagagcttg agcgtccttg tagctcataa agccaacagg aatgtgagct
     4321 tcctttggaa tagaggcctt ttcaatcgta aagcttcctt caagcgcatt gttattgtag
     4381 ataatcacac cgctagcacc agctttaaca gcattttcaa tcttttgata aaagctaagt
     4441 gagccgccac gttcaatcaa agcaaccttg cctttaatat caagaccagt aaagtgagag
     4501 gcttcaccga atttggcatc agccacaaag taatcctgat cagcatcaaa tgagtcgccc
     4561 tctgacataa agatcgctag tttttgacta ccgtctgcgg tcttagcatt aacagactgg
     4621 ctaatagcgt aaacaggatt ggaagccgca acactgataa cctcttcaaa aatagctgga
     4681 ctattaaggg taccaaaatc aggatttgct gctagaggct ctcgagttcc cataccaact
     4741 gcactctcat taccagctcc agcaaccaac aaaacaccct tttcttgagc ataggctata
     4801 gcctttttaa cgtcctcatg aaccgttgat aaggaatccg ctgtttttcc aaagctcatg
     4861 ctaatcactg tagctcctag attaaccgcg tctgtgatcg ccttagcata ggattttgca
     4921 aattgatccc tttctggggc accagtcacc ttcatcagca taagagaagc atttggtgca
     4981 atcccctcaa cacgaaggcc atttcctgct ggtgttttcc cattacctgc tgctatagcg
     5041 gcagtatggt taccatgacc attatcagcg gtcaagccgc caatatcatc tgattgcttg
     5101 gtgtaatcgt aggcaaaaat aattttttcg ttgtaccact taccgtatgt gattttctga
     5161 tcctgctttt tagcaagaaa tgcctcttta gcaggaatag tatcgctatt ttttaagtcc
     5221 gaatcaagct taaaggcgtc atgctcagga tcaaaggaaa catcaataac agcaataacc
     5281 gctccgcttc ccttttgtgt ttactcttgt agggctttag cgttgaccga gtcattcagt
     5341 gataaattgg tcggtgctgt gctctctggg ccttctgcaa aggctgatat ttctttttct
     5401 gttttagctt ctgtttctga agtcgcctgg ctgcttgaga attgtcatcc gtagcagtag
     5461 cttcaacagc tgcaactgga ttcacttgtg atacagaagc gtctaagtcc tgctgctcct
     5521 cagcaaatac agtctgacta tgaagcaata aaatacttgt tgtagccaat gttaactggc
     5581 ataataaact tttctttgag tgatattttt tagtcactaa taaaacct
//
LOCUS       DARYXW010000105         5468 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.106, whole genome shotgun sequence.
ACCESSION   DARYXW010000105 DARYXW010000000
VERSION     DARYXW010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5468
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.106"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            227..1780
                     /locus_tag="TV191_001732"
     rRNA            227..1780
                     /locus_tag="TV191_001732"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            2002..2074
                     /locus_tag="TV191_001733"
     tRNA            2002..2074
                     /locus_tag="TV191_001733"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2035..2037,aa:Ala,seq:tgc)
     gene            2382..5281
                     /locus_tag="TV191_001734"
     rRNA            2382..5281
                     /locus_tag="TV191_001734"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            5366..>5468
                     /gene="rrf"
                     /locus_tag="TV191_001735"
     rRNA            5366..>5468
                     /gene="rrf"
                     /locus_tag="TV191_001735"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1577 a         1102 c         1576 g         1213 t
ORIGIN      
        1 tcgtatacta gtgaagctgt cggcgagcac tagctcaagt taatgaaaaa aaggtaaaaa
       61 aagtagttga caaaggcagt ctaagctgat agaatgtaat agttgtctcg tgagacaaag
      121 acctttgaga actgaataag acgacctaaa cgtgcgggtt acggaagtaa cctgtcaata
      181 aagaaacaag tcagtaatga cgtcgagtta agagctcaaa cactgaatta acgagagttt
      241 gatcctggct caggacgaac gctggcggcg tgcctaatac atgcaagtgg aacgcacaga
      301 tgatacgtag cttgctacaa ttatctgtga gtcgcgaacg ggtgagtaac gcgtaggtaa
      361 cctagcttat agcgggggat aactattgga aacgatagct aataccgcat aaaagtggtt
      421 gacccatgtt aaccatttaa aaggagcaac agctccacta tgagatggac ctgcgttgta
      481 ttagctagtt ggtagggtaa aggcctacca aggcgacgat acatagccga cctgagaggg
      541 tgaacggcca cactgggact gagacacggc ccagactcct acgggaggca gcagtaggga
      601 atcttcggca atggggggaa ccctgaccga gcaacgccgc gtgagtgaag aaggttttcg
      661 gatcgtaaag ctctgttgtt agagaagaac agtgatggga gtggaaagtc catcatgtga
      721 cggtaactaa ccagaaaggg acggctaact acgtgccagc agccgcggta atacgtaggt
      781 cccgagcgtt gtccggattt attgggcgta aagcgagcgc aggcggtttg ataagtctga
      841 agttaaaggc agtggcttaa ccattgtatg ctttggaaac tgttaaactt gagtgcagaa
      901 ggggagagtg gaattccatg tgtagcggtg aaatgcgtag atatatggag gaacaccggt
      961 ggcgaaagcg gctctctggt ctgtaactga cgctgaggct cgaaagcgtg gggagcaaac
     1021 aggattagat accctggtag tccacgccgt aaacgctgag tgctaggtgt taggcccttt
     1081 ccggggctta gtgccggagc taacgcatta agcactccgc ctggggagta cgaccgcaag
     1141 gttgaaactc aaaggaattg acgggggccc gcacaagcgg tggagcatgt ggtttaattc
     1201 gaagcaacgc gaagaacctt accaggtctt gacatcccga tgctattctt agagataaga
     1261 agttacttcg gtacattgga gacaggtggt gcatggttgt cgtcagctcg tgtcgtgaga
     1321 tgttgggtta agtcccgcaa cgagcgcaac ccttattgtt agttgccatc attaagttgg
     1381 gcactctagc gagactgccg gtaataaacc ggaggaaggt ggggatgacg tcaaatcatc
     1441 atgcccctta tgacctgggc tacacacgtg ctacaatggt tggtacaacg agtcgcaagc
     1501 cggtgacggc aagctaatct ctgaaagcca atctcagttc ggattgtagg ctgcaactcg
     1561 cctacatgaa gtcggaatcg ctagtaatcg cggatcagca cgccgcggtg aatacgttcc
     1621 cgggccttgt acacaccgcc cgtcacacca cgagagtttg taacacccga agtcggtgag
     1681 gtaaccgtta aggagccagc cgcctaaggt gggatagatg attggggtga agtcgtaaca
     1741 aggtagccgt atcggaaggt gcggctggat cacctccttt ctaaggaaaa aggaagcacg
     1801 tttagcgtct tatttagttt tgagaggtct tgaaataagt catgagaacg ttaagaaacc
     1861 cgtatgacaa tagggaactg acgcagagtc gtaggactca aggaagtgat tctttttcac
     1921 tagggtttta gttcgaatac agtttggctt catacagacc attgataaga gtatacatat
     1981 acaagtacat ttatagtgta cggggcctta gctcagctgg gagagcgcct gctttgcacg
     2041 caggaggtca gcggttcgat cccgctaggc tccattatct aggatacaaa gagaagtttg
     2101 ggttacctaa ttttctgtat tctaagatat ataagatata gttcaagtaa ttgaacacga
     2161 cctcattttt taggaaaaaa gataaatctc ctcgtgtgta aagcacacat cgtcgatttc
     2221 ctatttttct acaaaaatgc ccaacaagtt gggacggtct tagtatctta atcttgtcca
     2281 ttgaaaattg aataactata tcatattccg caatcaaaaa agattgtaag aaagtaacaa
     2341 gaaataaacc gaaacgctgt gataacgagt ttaaaaaata aggttaagtt aataagggcg
     2401 cacggtggat gccttggcac tagaagccga agaaggacgt gacaaacgac gaaatgcttt
     2461 ggggagctgt aagtaagcaa agatccagag atgtccgaat gggggaaccc actagctaat
     2521 ggctagtatc cataactgtt aaggttatga gaaggaagac gcagtgaact gaaacatcta
     2581 agtagctgca ggaagagaaa gcaaacgcga ttgcctgagt agcggcgagc gaaaaggcag
     2641 gagggcaaac cgaagagttt actcttcggg gttgtaggac tgcgctgtgg gacgacaaga
     2701 ttatagaaga aggccttggg aagggtcgcc aaagagagta atagcctcgt attcgaaata
     2761 gtctttaacc ctagcagtat cctgagtacg gcgagacacg aggaatctcg tcggaatctg
     2821 ggaggaccat ctcctaaccc taaatactca ctagtgaccg atagtgaacc agtaccgtga
     2881 gggaaaggtg aaaagcaccc cgggagggga gtgaaagaga acctgaaacc gtgtgcctac
     2941 aagaagttcg agcccgttaa tgggtgagag cgtgcctttt gtagaatgaa ccggcgagtt
     3001 acgtttatgt gcgaggttaa gttgaagaga cggagccgaa gggaaaccga gtcttaatag
     3061 ggcgtaagta cgtggacgta gacccgaaac catgtgacct acccatgagc aggttgaagg
     3121 tgcggtaaga cgcactggag gaccgaacca gggcacgttg aaaagtgctt ggatgacttg
     3181 tgggtagcgg agaaattcca aacgaacttg gagatagctg gttctctccg aaatagcttt
     3241 agggctagcg tcgatatgaa gtctcttgga ggtagagcac tgtttgggtg aggggtccat
     3301 cccggattac caatctcaga taaactccga atgccaatga gatatgatcg gcagtcagac
     3361 tgcgagtgct aagatccgta gtcgaaaggg aaacagccca gaccaccagc taaggtcccc
     3421 aaataactgt taagtggaaa aggatgtggg gttgcacaga caactaggat gttagcttag
     3481 aagcagctat tcattcaaag agtgcgtaat agctcactag tcgagtgacc ctgcgccgaa
     3541 aatgtaccgg ggctaaaaca gtttaccgaa gctgtggatt accgttaagg taatggtagg
     3601 agagcgttct atgtgtgatg aaggtatact gtgaagagtg ctggaacgca tagaagtgag
     3661 aatgccggta tgagtagcga aagacaggtg agaatcctgt ccaccgtaag actaaggatt
     3721 ccaggggaag gctcgtccgc cctgggttag tcgggaccta aggagagacc gaagggtgta
     3781 tccgatggac aacaggttga tattcctgta ctagagtata tagtgatgga gggacgcagt
     3841 aggctaacta aaccggacga ctggaagagt ccggctaagc agtgaggtgt gatgtgagtc
     3901 aaatgcttac atctataaca ttgagctgtg aaggggagcg aagttaagta gcgaagttag
     3961 agacgtcaca ctgccaagaa aagcttctag cgatacgtat actctacccg taccgcaaac
     4021 cgacacaggt agtcgaggcg agtagcctca ggtgatcgag agaactctcg ttaaggaact
     4081 cggcaaaatg gccccgtaac ttcgggagaa ggggcgctga ctgaaggtca gccgcagtga
     4141 ataggcccaa gcaactgttt atcaaaaaca cagctctctg ctaaatcgta agatgatgta
     4201 tagggggtga cgcctgcccg gtgctggaag gttaagagga gtgcttagcg caagcgaagg
     4261 tatgaattga agccccagta aacggcggcc gtaactataa cggtcctaag gtagcgaaat
     4321 tccttgtcgg gtaagttccg acccgcacga aaggcgtaat gatttgggca ctgtctcaac
     4381 gagagactcg gtgaaatttt agtacctgtg aagatgcagg ttacccgcga caggacggaa
     4441 agaccccatg gagctttact gcagtttgat attgagtatc tgtaccacat gtacaggata
     4501 ggtaggagcc atagaagtcg ggacgccagt ttcgatggag gcgatgttgg gatactaccc
     4561 ttgtgttatg gctactctaa cccggatagg tgatccctat cggagacagt gtctgacggg
     4621 cagtttgact ggggcggtcg cctcctaaaa tgtaacggag gcgcccaaag gttccctcag
     4681 attggttgga aatcaatcgc agagtgtaaa ggtataaggg agcttgactg cgagagcaac
     4741 acctcgagca gggacgaaag tcgggcttag tgatccggtg gtaccgtatg gaagggccat
     4801 cgctcaacgg ataaaagcta ccctggggat aacaggctta tctcccccaa gagttcacat
     4861 cgacggggag gtttggcacc tcgatgtcgg ctcgtcgcat cctggggctg tagtcggtcc
     4921 caagggttgg gctgttcgcc cattaaagcg gcacgcgagc tgggttcaga acgtcgtgag
     4981 acagttcggt ccctatccgt cgcgggcgta ggaaatttga gaggatctgc tcctagtacg
     5041 agaggaccag agtggactta ccgctggtgt accagttgtc tcgccagagg catagctggg
     5101 tagctatgta gggaagggat aagcgctgaa agcatctaag tgcgaagccc tcctcaagat
     5161 gagatttccc ataacgttaa gttagtaaga gccctgagag atgatcaggt agataggtta
     5221 ggagtggacg tgtggtgaca catggagcgg actaatacta atagctcgag gacttatcca
     5281 aaagatgaaa ccagtcgcta ttgacagctt aaggaattct tgttagacta tagttattca
     5341 attttgagtg gagaagactc gtaagttaag tgacgatagc ctaggagata cacctgtacc
     5401 catgccgaac acagtagtta agccctagaa cgcctgaagt agttgggggt tgccccctgt
     5461 gagatacg
//
LOCUS       DARYXW010000106         5325 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.107, whole genome shotgun sequence.
ACCESSION   DARYXW010000106 DARYXW010000000
VERSION     DARYXW010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5325)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5325)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5325
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.107"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(150..389)
                     /locus_tag="TV191_001736"
     CDS             complement(150..389)
                     /locus_tag="TV191_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEL1508218.1"
                     /translation="MAQQRRGGFKRRKKVDFIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPYVNED"
     gene            complement(548..1036)
                     /locus_tag="TV191_001737"
     CDS             complement(548..1036)
                     /locus_tag="TV191_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL1508219.1"
                     /translation="MINNVVLVGRMTKDAELRYTPSQVAVATFTLAVNRAFKSQNGER
                     EADFINCVIWRQQAENLANWAKKGALIGITGRIQTRNYENQQGQRVYVTEVVADNFQM
                     LESRATREANSSGSYGGGFNSSPATNSYSAPAQQTPNFGRDGSPFGGSNPMDISDDDL
                     PF"
     gene            complement(1055..1345)
                     /locus_tag="TV191_001738"
     CDS             complement(1055..1345)
                     /locus_tag="TV191_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEL1508220.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATIVESKDWE
                     KRRLAYEINDFREGLYHIVNLEATDAVALNEFDRLSKINGDILRHMIVKLDA"
     gene            2721..3869
                     /gene="mutY"
                     /locus_tag="TV191_001739"
     CDS             2721..3869
                     /gene="mutY"
                     /locus_tag="TV191_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEL1508221.1"
                     /translation="MIDLNDYGITMWDQDTIASFRRTLLAWYDQEKRDLPWRRTKDPY
                     HIWVSEIMLQQTQVVTVIPYYERFLDWFPTVEALACADEERLLKAWEGLGYYSRVRNM
                     QKAAQQIMTDFGGIFPSSHADITKLKGIGPYTAGAISSIAFDLPEPAVDGNVMRVMAR
                     LFEINYDIGDPKNRKIFQAVMEVLIDPERPGDFNQALMDLGTDIEAAKNPRPDESPVR
                     FFCAAYRHGTYDKYPIKEPKKKPRPIQVQAFVIRDSKGRLLLEKNTQGRLLGGFWAFP
                     LIETKLVSQQLTLFEDSPIVLETMSQTTLFEERYGLMPIWSQATFPQVKHTFSHQKWT
                     IELCEGFTDSMPLAPDRELVWVAIEDMAAYPMATPQKKMLEAYLKKQS"
     gene            4640..>5325
                     /locus_tag="TV191_001740"
     CDS             4640..>5325
                     /locus_tag="TV191_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface-anchored protein"
                     /protein_id="HEL1508222.1"
                     /translation="MNKKSARRRRKNLITKLAMTSALTLGVGAATTLAGQTEVRADNI
                     LRLDMTDKEAVEKFANELKNEVHKNYRGSNTWQKLTLILNGYQNLREQIETELKNSEQ
                     KVKELNDKVNSETQGKQELQNQLEKEKEELETLKKELEAEKAKGTGETEKLQKEIEAK
                     NAMISDLQKQLEETKQRVQEFEAEVGKLMAEKADLQTKLNEQEQLNAKLQKEIEDLKA
                     QIEKLKHCQDT"
BASE COUNT         1622 a         1165 c         1062 g         1476 t
ORIGIN      
        1 cttagatgag gagtttttct ttagccctat gcttcatcaa acaccaccag ataccacact
       61 ctcaatcaga tcacaggcta aggcttgacg acgctgctca gctgacttca gaccacataa
      121 aaaacagccc ttaaggactg tttcagatat tagtcttcgt ttacgtaagg cataagtgcc
      181 ataacacgag cacgtttgat agctgttgtt actttacgtt ggtttttagc tgatgttcct
      241 gttacacgac gaggaaggat tttcccacgt tctgaaacga aacggctaag aagctcagta
      301 tctttgtaat caacatattc aattttgtta gctgcgataa agtcaacttt tttacggcgc
      361 ttgaatccgc cacgacgttg ttgagccatg tgttatctcc tttatattat tcacatgata
      421 aatttgctgc ctaataagca aaccgacgcc agaaagaggc ctcaatcttt tgtgcttgaa
      481 agcaactcct ctgtctccca agctaccagc aaatctatgc aattcatgtc agtccacttt
      541 ccattgctta gaatggaaga tcgtcatctg aaatatccat tggatttgag ccgccaaatg
      601 gacttccatc tctgccaaag ttaggtgttt gctgagcagg cgctgaatag ctattggttg
      661 ccggtgagct attaaaacca ccaccatatg agccagacga gttcgcctca cgtgtagcac
      721 gactttccag catttggaaa ttatctgcaa caacctcggt tacatacaca cgctgcccct
      781 gttggttttc gtagttacga gtctgaatac gtcccgtaat cccaatcaag gcaccctttt
      841 tagcccagtt agctaaattt tcagcttgct gacgccagat cacacagtta atgaaatccg
      901 cttcgcgctc accattttgg ctcttaaagg cgcgattaac agcaagtgta aacgtagcaa
      961 ctgccacctg acttggagtg tatcgaagct ctgcgtcctt ggtcatacga ccaactagta
     1021 ctacattatt aatcataaac tacctacttt gcaattaagc gtcaagctta acgatcatgt
     1081 gacgaagaat gtcaccgttg atttttgaca gacggtcaaa ctcattaaga gctacagcgt
     1141 cagtcgcttc aaggtttacg atatggtaaa ggccttcgcg gaaatcattg atttcgtatg
     1201 caagacgacg cttttcccaa tcttttgatt caacaatagt tgcaccattg tcagtcaaga
     1261 tagagtcaaa acgtgctacc aaagcgtttt tagcttcttc ttcaatgttt ggacgaatga
     1321 tataaagaat ttcgtattta gccattgata gtttcctcct tttggtctaa tgactcgcta
     1381 cccttgtaac gagtaagtga ggtatgctca cagattaaca gtatacaata aacaaaggta
     1441 aaaagcaagc aaaatgttga cctttctgtt gaataaaaga ccttcttaga tcccttcgta
     1501 gctccataaa aagcaaagcc acttctatag aaatgacctt tagtcacctg acttgcaggt
     1561 cttagtggca aggtcaaatc cagacaccag caaaaaggac acccaaccgg gtgtccttat
     1621 catgtcttga gtgctattct cccttctatc tgccatttaa taaggagtca cctgtcaatt
     1681 gttcctctaa agaggaacac atacttatct gtctaatcag tcgtctcctt tctgtttaac
     1741 aaaatgaacg gttattaaaa gaatatgact gttcttgagt ttcgtttgtt agcactgtgc
     1801 tattttggct tacattggac tcactccttc agctattttt tgctgtcgtg ctcaatgtct
     1861 ccgtttttat atcttgcgat gtacataaga ccctcctatt agaaaagctc actagctatc
     1921 tgatgatagc tacctttcaa ataagctcaa tcctttaccc tgagtgccaa taacaatatc
     1981 aaggacgact agtgacacag caactagtct ccatttttat agcgtccttt attgaatctt
     2041 agcatagcat acgtcctttc aataacggga atttcaagct tatactgttt agagcgctcc
     2101 tttggccaaa gctggtaatc tcgataagcc ttcacatgtg atcacatatt aaattgtaaa
     2161 attggttttg cctaccgttt gttggagctc ttaatctcca tttttgtacc gcgcgacatg
     2221 tcttgttatc atcagatatc ctcctataac tccagtgtca tcggtcgtcc ttatctacat
     2281 ctttattata atgtaagcgg ttactaaagt caagcttttt gctccttttt tgataacata
     2341 tcagcaacta aaaccccacg ataggacaca agccttcagc aaagactgag aaccttttta
     2401 tacttgtcat ttacgttcaa gtgcctttgt caatacctca gagtcattaa ccttttcgcg
     2461 gtcagctaat ctaaccaacc actctgaaac ggtaacagtt ttacgaacag ctttattatt
     2521 tttgataaat ggtgttgaat cagcttgtag gaactggtaa attcagacca caatcaatat
     2581 aagcagcaag aacattttct aacatgtcat gagcagttgt cacagcctct ttataaggta
     2641 taaatcacaa agcatgcttt aacaaatcct atcggacgca gggttcaacc aattcagaca
     2701 atctgtgtta caataggatt atgatagatt taaatgatta tggcattacc atgtgggatc
     2761 aagataccat tgcctccttt cgtcgtacgc tgctagcttg gtacgatcag gaaaagcgag
     2821 acctgccttg gcgtcgcaca aaggaccctt atcatatctg ggtctcagag atcatgctcc
     2881 agcaaacgca ggtcgttacc gttattcctt attacgagcg atttttggat tggtttccaa
     2941 cggtagaggc cctcgcctgc gctgacgaag agcgcttact caaggcttgg gagggactgg
     3001 gctactactc tcgtgtacgc aatatgcaaa aggctgcgca gcaaatcatg actgactttg
     3061 gcgggatttt cccaagctca cacgctgata ttactaagtt aaagggcatt ggcccttata
     3121 cagctggcgc tatctcaagc attgcctttg atctgcctga gcctgcggtt gatggcaatg
     3181 tcatgcgagt catggccaga ctgtttgaga ttaattacga tattggagac cctaagaacc
     3241 gcaagatttt tcaggctgtt atggaggtgc ttatcgatcc ggagcgaccc ggagatttca
     3301 atcaagcctt gatggatctg gggactgata ttgaagcggc taaaaatccc agacctgacg
     3361 agtctcctgt gcgctttttc tgtgcagcct accgacatgg tacctatgac aaatacccca
     3421 tcaaggagcc aaagaaaaag ccccggccta ttcaggtgca ggcctttgtg attcgtgaca
     3481 gcaaggggcg gcttttgctc gaaaaaaata cccaagggcg cttgctaggt ggcttttggg
     3541 cctttcctct gatagagacc aagcttgtca gtcaacaact gaccctcttt gaggacagtc
     3601 ctatcgtgct tgagaccatg tctcagacaa ccctttttga ggagcgttac gggcttatgc
     3661 ctatctggtc tcaagctacc tttcctcagg tcaagcatac ctttagccac caaaaatgga
     3721 ccattgagct ttgcgagggc ttcacagaca gcatgcccct agcccctgac agagaacttg
     3781 tctgggtcgc aatagaggat atggctgctt acccaatggc aaccccacaa aagaaaatgc
     3841 tagaagccta cctaaaaaaa caaagctaag cggctcatag ctgtcagata aggtccttaa
     3901 ggcagagctt tagggacttt tttgcttgcc caaggagctt acttgtagcc tacttggtct
     3961 gatcagacaa gaaaaactcg atttcttgta acaaagtcag acgattaccc ttttcattaa
     4021 aaaaacgaaa ctacggagac aaattgggac actgctatgt cttgtcgtca gctgtcgtgc
     4081 tacactggcc ttagaaacta agcacagcca aaagctgtga aaactataac tatattatgg
     4141 aggagaaaac acaatgaagc tgacaaatgc cctatgccta gtagccgcta ctgcagccct
     4201 agccctagca ccaatcaaca caagcactgg acaaactaat accgttttgg caagtcaaaa
     4261 aagtacagga cattgtactc atactagaag tggatggttt aaatgccctg atggaggatc
     4321 atattacgac gaaagttacg atacacattc atcatggtta atttggcttt atggtgcttt
     4381 ttactctgca tgggaaatta taactagttg gttcaaataa attagtaaag caggtcaggt
     4441 tattatcggc ctgcttttct taatcagcct tgctaatgcc tgctgaattg ccagaaatca
     4501 gacaattagc cttttcatta aaaccaaaaa ccgaacgaat ctaggagaga aagtagcgga
     4561 caactatttc tctatcttga tgactgtgtt aaaatatctt cagtcaaaat taatatgtct
     4621 atcattaaag gagagagaaa tgaacaaaaa atcagcaaga cgcaggcgta agaatcttat
     4681 tacgaagctt gcgatgacaa gtgccttaac cctgggtgta ggcgcagcga ctaccctagc
     4741 aggacaaaca gaagtacggg ctgataatat cttacgctta gatatgacag ataaagaagc
     4801 agttgaaaaa ttcgctaacg agcttaaaaa tgaagtccat aaaaactatc gtggtagtaa
     4861 tacttggcaa aagcttaccc ttatacttaa tggttatcaa aaccttagag aacaaataga
     4921 gaccgagcta aaaaatagtg aacaaaaagt aaaagagctt aatgataagg ttaatagtga
     4981 aactcaagga aaacaagagt tacagaatca gcttgagaaa gaaaaagaag agttagaaac
     5041 actaaaaaaa gagcttgaag ctgagaaggc taaaggaact ggagaaacag agaagcttca
     5101 aaaggaaatt gaagcaaaaa atgcaatgat ttctgaccta caaaaacagc ttgaggaaac
     5161 taagcaaagg gttcaagagt ttgaagctga agtaggtaaa ttaatggccg aaaaggcaga
     5221 cctacaaaca aaattaaatg aacaagagca gcttaacgct aagcttcaaa aagaaattga
     5281 agacttaaag gctcagattg aaaagcttaa gcactgtcaa gatac
//
LOCUS       DARYXW010000107         5162 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.108, whole genome shotgun sequence.
ACCESSION   DARYXW010000107 DARYXW010000000
VERSION     DARYXW010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5162
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.108"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            <1..519
                     /locus_tag="TV191_001741"
     CDS             <1..519
                     /locus_tag="TV191_001741"
                     /inference="COORDINATES: protein motif:HMM:NF019104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-1-phosphate
                     uridyltransferase"
                     /protein_id="HEL1508223.1"
                     /translation="ASSIVNGQDLYNAIEQYGTIGRGKSGNFATSMAEDIALLYDSSG
                     NLVSSGMIEAIKGVDEGKYLSGAFQYEYSPQFVKSFDQIGEVRTVTGKTPGSSLLNIP
                     GAKTWAGKNMALSQSELMMPSIDTSNLKLEDVLLSMESTGIYTLNNPTIVLKDGTKKI
                     VEGQFIIRKLGN"
     gene            521..1027
                     /locus_tag="TV191_001742"
     CDS             521..1027
                     /locus_tag="TV191_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508224.1"
                     /translation="MTQTFFNNDVDERRRQLYLDARSKGHLEKCFRGDSGFKINAKDS
                     YFQSITDINVLIERCLYPLYDLGDSIIPHETERILSQFSTSKNVVELYQVVSYIFYQK
                     NNKLLKKNFSFYIDFNPMIPDLVFSVKRLSPENIVTDDEKAMVGFIKNMFQKIPQVQS
                     YLEAQNCK"
     gene            1171..1593
                     /locus_tag="TV191_001743"
                     /pseudo
     CDS             1171..1593
                     /locus_tag="TV191_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678587.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2122..2847
                     /locus_tag="TV191_001744"
     CDS             2122..2847
                     /locus_tag="TV191_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEL1508225.1"
                     /translation="MLEKPSKAELLTALKDGLIVSCQALPGEPLYSEAGGIMPLMAKA
                     AEEAGAVGIRANGVRDIKEIQAVTDLPIIGIIKKEYPPQAPFITPTMAEVDALAALDV
                     AVIALDCTQRERHDGLAIADFIRSIRKKYPEQLFMADISTLEEGLVAYEAGIDFVGTT
                     LSGYTPYSRQGTGPDMELISALCDAGVSVIAEGKIHSPEEARAVQALGVAGIVVGGAI
                     TRPKEIAERFVAALKKEEKSHGF"
     gene            2837..4348
                     /locus_tag="TV191_001745"
     CDS             2837..4348
                     /locus_tag="TV191_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEL1508226.1"
                     /translation="MDFKKFSKLGQAFMLPISILPVAGLLLGIGGALSNSNAIAQFPI
                     LNQAWLQAIFTIMSTAGNAVFANIALIFAIGVAVGLANGDKGTAGLSGAVAYLVFTAT
                     ISGYLTLFSAKDAQIDTGVLGALTVGLVVVSLHNKYRKIELPAFLGFFGGSRFIPIVS
                     SLAAIVIGSVFYVIWPPIQNLLVVFGEKIADMGSIGTFLYGFFLRLTGAVGLHHTIYP
                     MFWYTSLGGSEVVAGETIQGAQNIFFAQLADANHTDLFTYGTRFFAGRFATMMFGLPA
                     ACLAMYHAIPKANRKKVGSFYSSSALTSLLTGITEPIEFAFLFVAPWLYVVHAFLDGC
                     SFLVADLLKIRIGNSFSGGLIDFLIFGVFQGNDHTNWLLVIPVGIVWFMVYYFVFKFF
                     VSKFQVAVPGMVAQVEAEGQAETTNTQSSSLREVSLAIIEALGGQANIEDVTACATRL
                     RVSLSDSSLVNKNVLTSLGATAVLDVKNGIQAIYGGKAILYSQEINQLLGRED"
     gene            4350..4865
                     /locus_tag="TV191_001746"
     CDS             4350..4865
                     /locus_tag="TV191_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEL1508227.1"
                     /translation="MIKKWKQLLSAKKADALSDRILSVAKGQLVPITSVSDPVFSERL
                     MGDGFAIIPQEGAIYAPVTGRVMTVFPTKHAYGIVTPAGLEVLIHIGVDTVELGEAAF
                     SSDIVAGQEVVAGQLLAQVSLPVLEAAQKDSTVMVVFTNSQDIADMRLADAGAVAARA
                     EVGQVRLKATL"
BASE COUNT         1490 a          868 c         1219 g         1585 t
ORIGIN      
        1 gcatcatcaa ttgtgaatgg tcaagatttg tataatgcaa ttgagcaata tggtaccatt
       61 ggaagaggta aatcgggaaa ttttgcaaca agtatggctg aagatatagc attactttat
      121 gatagtagtg gtaatttagt ttcttccggt atgatagagg ctatcaaagg ggtagatgaa
      181 ggtaagtatt tgtctggtgc atttcagtat gaatatagtc ctcagtttgt taaatctttt
      241 gatcaaatcg gtgaagtgag aacagttact ggtaaaactc caggttcttc acttttaaat
      301 attccagggg ctaaaacttg ggcaggtaaa aatatggctt tgtcacagtc tgaattaatg
      361 atgccatcta ttgatactag taacttaaaa ttggaggatg tattattaag tatggaatca
      421 acaggaattt ataccttgaa taatcctaca atcgttttga aagatggcac taaaaagatt
      481 gttgaaggac aatttataat tagaaaatta ggtaattaat atgacacaaa cattttttaa
      541 caatgacgtt gatgaaagac gtcgacaact ttacttagat gctcgttcaa agggacactt
      601 agagaagtgc tttagagggg attctgggtt taaaataaat gctaaagact catattttca
      661 atcgatcaca gatataaatg tgcttattga gcgctgcttg tatcccttgt atgatttagg
      721 agatagcatt atcccacatg aaactgaaag aatactgtct caattctcaa cttcaaaaaa
      781 tgttgtagaa ttatatcaag ttgtgtcata tattttctat caaaagaaca acaaactact
      841 aaagaagaac ttttcctttt atattgattt taatcctatg atccctgatt tagttttttc
      901 tgttaaaagg ttatctcctg aaaatatcgt gactgatgat gaaaaagcga tggttggttt
      961 tataaaaaac atgtttcaaa aaattcctca ggtacagtct tatcttgaag ctcaaaattg
     1021 caaatagttt agatgaatac ttgaaaaatg gatttgaaat agcttaaata aaaatagagt
     1081 atgcttttca atcagacgag gtaagggtat tattggaaaa agattgagca gtatttatcg
     1141 attaagctat aaaaacgaaa gataacacac atggcacgca gtcaattaac atgggaagat
     1201 gttagtcaat atgaggaaat caagggttat ggccaacagg tttggaagca tcagggagaa
     1261 tattatctag tcagagaaga aggaggaatt gctgtacaac gagtagtgta taaactccct
     1321 aatgagcttt tccaattact ggaaagtgac cgaaaatttt tattagaaat agatttttat
     1381 gtcaaaaata actgctggct gccaacagaa gaggagaaaa tagctagtga taaagcattt
     1441 ctacaaagat ccccaatagc attaattgca gatccaacca gttgggaact gtttacctaa
     1501 gaagagctaa gaaaactaat tccaattgcg gagcaaaaat ggatagattg gaagggaaaa
     1561 ctgccagatg attatgtcag tcctttgaaa taatgtttaa gatagcggat ctgagggcag
     1621 ctatgttagg ggccgttgtt agctgtatta ggtaggtgaa aagtggttat ttttgggtac
     1681 aatcaaaagt tctatatata acccttgcgg tggagttacc cactacgggt attgtagagc
     1741 ttgaaaagct gggtgcgaga gaggactgga ctggttctct cttttttgtc tctttgtcaa
     1801 gcttatcaag caataatagg acctaaggta gttcttgttg agacatattg ccgtatttgg
     1861 ccttagctgg ctggcaaaaa ggcttttatg gtaagaaggt atgtcttgta aggttttgct
     1921 gttgttgtat caattagtaa atagctcaat aggctagctc tttgccatac ttaaggctat
     1981 tgaatatact ttcagaaaac aaggattttt ctctgaaaat gaaagtactt cctaaaagtg
     2041 ggctgtctat tgaaagtgtt ttaatatctg ctacaataaa gatgtgaacg ttctctaaaa
     2101 ttaataaaag gagtagaaag catgcttgaa aaaccaagca aggcagagct actgacagct
     2161 ctgaaagacg ggctgatcgt ttcctgtcaa gctctgccgg gcgagcctct ctattcagag
     2221 gcaggaggta tcatgcctct gatggcaaag gcagcagagg aagcaggagc agtagggata
     2281 agagctaatg gggttcgaga tattaaggaa atccaagcgg tgacggatct gccaatcata
     2341 gggatcatca aaaaggagta tcctccgcaa gcgcccttta tcacgccaac catggcagag
     2401 gtagacgcct tagcggcctt agatgtagcg gtgatagcct tggattgtac gcaaagggag
     2461 cgtcatgatg gcttagcgat agcggacttt attcgatcga taaggaagaa gtacccagag
     2521 cagctgttta tggcagacat cagtacgctt gaagagggtc tagtagccta tgaggctggt
     2581 atagattttg tagggacgac cttatcaggg tatacgcctt atagtcgtca ggggacaggt
     2641 ccggatatgg agctgataag tgccttgtgt gatgcagggg tatcagtgat agctgagggc
     2701 aagattcata gtccagagga ggccagggct gttcaggctt tgggagtagc tggtattgtg
     2761 gttggtggtg ctattaccag accaaaggaa attgcagagc gctttgtggc ggctctcaag
     2821 aaggaggaga aatcacatgg attttaagaa attttcaaaa ttgggtcaag cctttatgct
     2881 gccgatctca atcttaccag ttgctggttt gttgttgggg attggtgggg ccctgtcaaa
     2941 tagcaatgcc attgcacaat ttccgatatt aaatcaagca tggctacagg ctatttttac
     3001 cattatgagc acagcaggta acgctgtttt tgctaatatt gccttgattt ttgcgattgg
     3061 tgttgctgtt ggcttagcca acggagataa aggaacagcc ggtctttcag gtgctgtggc
     3121 ttatttggtc tttacggcaa ccattagcgg ctatctgact cttttttcag caaaggacgc
     3181 tcagattgat acgggtgttt taggggcttt gacggttggc ttagttgttg ttagccttca
     3241 caataagtac cgaaagatcg aactgccagc ctttttaggc ttctttggcg gctctcgttt
     3301 tattccgatt gtttcctcat tggcagcgat tgtgattggt agtgttttct atgtcatttg
     3361 gccacctatt caaaatctcc tagtagtgtt tggtgaaaaa attgcggata tggggagcat
     3421 cggaacattc ttgtacggtt tctttttacg tctgacagga gcagtagggc tgcaccacac
     3481 catttaccca atgttttggt atacatcact tggcggtagt gaggttgtag caggtgagac
     3541 tatccaagga gcacaaaata tcttctttgc gcaattggct gatgctaacc ataccgactt
     3601 gtttacttac gggacacgct tttttgcagg acgttttgca accatgatgt ttggactacc
     3661 tgctgcctgt cttgctatgt atcacgctat tccaaaggct aatcgtaaaa aggttggtag
     3721 cttttattca agtagtgcct tgacttcctt actaacaggg atcacagagc ctattgaatt
     3781 tgccttttta tttgtagccc cttggctcta tgtagttcat gctttcttag atggttgttc
     3841 tttcttagtt gctgatttat taaagattcg tatcggtaat tccttctcag gtggtttgat
     3901 tgacttttta atctttggtg tgttccaagg aaatgatcat accaactggc tacttgttat
     3961 ccctgttggt atcgtgtggt ttatggttta ttactttgtc tttaaattct ttgtgagcaa
     4021 attccaggtt gctgtaccgg gaatggtagc tcaggtagaa gcagaaggac aagcagagac
     4081 tactaatact caaagctcat cacttcgtga ggtgtcatta gctattattg aggctttggg
     4141 aggacaagct aacatcgaag atgtaaccgc ttgcgcgact cgcttgagag tgtctctgtc
     4201 agatagcagc ttggttaaca agaatgtttt aacctcactg ggagcaacag ctgtattaga
     4261 tgttaaaaat ggcattcagg ctatttatgg tggtaaggct atcttgtata gtcaagaaat
     4321 caatcaacta ttaggtagag aagattaaca tgataaagaa gtggaagcaa ttattatcag
     4381 caaaaaaagc tgatgcgtta agcgatcgta ttttatcagt ggctaaggga caattagttc
     4441 ctattaccag tgtcagtgat cctgtctttt cagaaaggct aatgggcgat ggctttgcta
     4501 ttattcctca ggagggcgct atttatgcac ccgtaacagg aagggtcatg acggtttttc
     4561 cgaccaagca tgcttatggc atcgttactc cagctggtct tgaggtcttg attcatatcg
     4621 gtgttgatac tgttgagctg ggagaagctg cctttagctc tgatattgtt gctggtcagg
     4681 aggtagtagc tgggcagtta ttggctcagg tctctttgcc agtgcttgaa gctgctcaaa
     4741 aagacagcac cgttatggtt gtctttacaa actcacagga cattgctgat atgcgtcttg
     4801 ctgatgctgg agcagttgct gctagggcag aagtcggcca agttaggcta aaggctactc
     4861 tctagctaga ggctatcgat ccagtccttg atgacaacta aaaggtcata tgaaaaaact
     4921 gcaccccagc acttggctaa gtcggtcaat gccttggggt gcttttatta ttgtcagcaa
     4981 tcagcaggct ttgattgtcc tatcttttaa cctctattta aatgttaaca gctgtcgtat
     5041 gtgccttgtg gcaaataaaa gaaaagctca gcgacctgtt tctcatattg cttagcacat
     5101 tttattttag gggggctatt atatcctccc cagtatacaa gggctgaaaa aggaaaatag
     5161 ag
//
LOCUS       DARYXW010000108         4873 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.109, whole genome shotgun sequence.
ACCESSION   DARYXW010000108 DARYXW010000000
VERSION     DARYXW010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4873)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4873)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4873
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.109"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            <1..>4873
                     /locus_tag="TV191_001747"
     CDS             <1..>4873
                     /locus_tag="TV191_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEL1508228.1"
                     /translation="IWLNPVSKNNHQIPIVSFSDREELNEKLIVIDTNLNLGEDKSEL
                     LHHSLDVINDKGSVIANQFIVKVDNQNRELTVYSEQNPNSHREFELSFDYLNGLGQID
                     GDGNNLKLTKHKKETIDKKLKSYHSWKEDGEKRGIPGIAGSSITSPITDEMFWQMKEY
                     EEKLKEEERYAPDDKYLGGIPPINYKITKEDEILPPSERLKNNIEAIKVLKEIEERHS
                     HATKEEQDILSRYVGWGGLSDVFDEEKGGQWKDAREFLKENLSPSEYDAARESTLTAF
                     YTPKIVIDSIYQAVLNMGFESGNILEPSMGTGRFIGNLPDSMKGSKFYGVELDSISGR
                     IASRLYPNAKIQIKGFEETTFSNNLFDVAVGNVPFGEYKIVDREYEKNNFLIHDFFFA
                     KTLDKVRSGGVVAFISSSGTMDKKSEDIRRYISERAEFLGAIRLPNNTFKGEAGTEVT
                     SDIIFLKKRDRLVKLDEEWVKLGTDERGLTYNKYFVDNPDMVLGNMEEISSRFGTSLA
                     CVADENSTLKEQLDTAIKNIKGSYEKIELNNEFEVETIPADDSVKNYSYAVIDDKVYF
                     RENSVMQKLNLNKNDEEKVRAYLGIEKALRQVIAYQKEDYSDTEIKEKQGELNRIYDE
                     FSKKYGILNSKANKKLFREDANYSLLSTLEKLDKEGNFIEKSDIFTKRTIKKAVAIEH
                     TDNLTEALILSISQKGKVNFEYMEKLTEKTRGEIIEGLKGEIFLNLDGFDPSDTTPFS
                     SAIDLGDFSRSYVTADEYLSGNIRDKIEVIDSYIKNVEHEFEQNEQLENIDADVLKQG
                     SETLKKELSSLNYQRQKLLEVMPKELEASEITVRMGATWIPEKDYKSFMFHLLKTSAS
                     NRWNIDIKYTNFTGEYRVEGKSIDKGNDLANFTYGTSRVSAYKLIEDTLNLRDTNVYD
                     QVIDENGKKSSVLNQKETMLARSKQEIIKEEFKNWIFDDIDRRTRLVKEYNEKFNSIR
                     LREYDGSNLTFDGMNPEIELRPHQRDAIARGLFGGNTLLAHEVGAGKTFEMIGIAMES
                     KRLGMSNKSMFVVPNHIVEQFGREFNELYPAANILCATEKDFTPDKRKRFCSRIATGD
                     YDAVIIGHSQFEKIPISKQRQEYELQSQIDEIIDFIEEYKRNRDQKFTVKQLEKTKKG
                     LEAKLKKLNDDYRKDDVVTFEELGIDKLFVDEVHAFKNLYVFTKMRNVAGITTTDSQK
                     SSDMLMKCRYMDEITGNKGIVFATGTPVSNSMAELYTMQRYLQYDELKKMHLQHFDSW
                     ASTFGETVTAIELNPEGNGYRSKTRFAKFYNLPELMNMVKQFMDIKTADVLNLPVPNA
                     HYETIKTKPTEEQKQILETFSERADKVRGKQVDSSVDNMLLITNDGKKMALDQRLINP
                     LLPDDPNSKVNTCVNNIFSIWDKYRDEKSTQLVFCDMSTPSSEFNIYDDIKEKLTKMG
                     IPKNETEFIHNAKNNKEKDKIFDKVRKGEIRVLLGSTQKMGAGTNAQNKLIATHDLDV
                     PWRPADLEQRKGRIVRQGNENDDVHIFRYITENTFDAYLFQTLETKQTYISQIMNSKT
                     PVRVAEDIDEATLNYAEIKALATGNPLIREKMDLDVEVSKLKMLESNFKSNLYKMEDK
                     VVKVYPKEIKSLK"
BASE COUNT         1901 a          653 c         1012 g         1307 t
ORIGIN      
        1 atatatggct aaatcctgta tcaaaaaata atcatcaaat tccgattgta agtttttctg
       61 acagagaaga gctaaatgaa aagctcattg ttatagatac caatcttaac ttaggagaag
      121 acaagtcgga actgttacat catagtttag atgtaataaa tgataaaggt tctgtgattg
      181 ccaatcagtt tattgtaaaa gtcgataatc aaaacaggga acttacagta tatagtgaac
      241 aaaatcctaa tagtcataga gaatttgaac tttcttttga ttatctaaac gggcttgggc
      301 aaattgacgg agatggaaat aatctaaaac ttacaaagca taaaaaagaa accattgata
      361 aaaaattgaa aagttatcat tcttggaaag aagatgggga aaaaagagga attccgggaa
      421 tagcaggttc ttctattact tcacctatta ctgatgaaat gttttggcag atgaaagaat
      481 atgaagaaaa attaaaagag gaggaaagat acgcccctga tgataagtat ttgggaggta
      541 ttcctccaat caattacaaa atcacaaaag aagatgaaat cttgccgccg tccgaaaggc
      601 ttaaaaataa catagaagcc atcaaggtat taaaagaaat tgaggaaaga catagtcatg
      661 caacaaagga agaacaggat attttgagta gatatgtcgg ctggggtgga ctttctgatg
      721 tctttgatga agaaaaggga ggacaatgga aagatgcaag agaattctta aaagaaaatc
      781 tatcaccgtc tgagtacgat gcagcaaggg aaagtaccct tacagccttt tatacaccga
      841 agattgtaat agacagtatc tatcaagccg tattaaatat gggatttgaa agtgggaata
      901 tcttggaacc aagtatggga actggcagat ttataggcaa tcttccagac agcatgaaag
      961 gcagtaaatt ttatggtgta gaacttgaca gtataagtgg taggatagca agtaggctat
     1021 atcctaatgc taaaatacag atcaaaggtt ttgaagaaac gactttttca aataatctgt
     1081 ttgatgtagc ggtgggaaat gtaccgtttg gagaatataa gatagttgat cgtgagtatg
     1141 agaaaaacaa ttttcttatt cacgattttt tctttgccaa aaccttggat aaagtacgtt
     1201 ccggtggagt agtagccttt ataagttcaa gtggaactat ggataaaaag agtgaagata
     1261 tcagaagata tatttcagaa agagcagagt ttttaggagc aattagacta cctaataata
     1321 cttttaaagg cgaggcgggt acggaagtaa caagtgatat tatttttctt aaaaagagag
     1381 atcgactggt aaaacttgat gaagaatggg taaaacttgg cactgacgaa agaggactga
     1441 catataacaa atactttgta gataaccctg atatggtact tggaaatatg gaagaaatat
     1501 caagcagatt tggaacaagt cttgcctgtg ttgcagatga aaatagtact ctgaaagaac
     1561 agctggatac cgccattaaa aacattaaag gaagttatga gaagatagaa ttaaataatg
     1621 aatttgaagt ggaaaccatt ccggctgatg acagtgtgaa aaattattct tatgcagtaa
     1681 ttgatgataa ggtatatttt agagaaaatt ccgttatgca aaaattgaat ttaaataaaa
     1741 atgatgagga aaaagtaagg gcatatcttg gaatagaaaa agcattaaga caggtaattg
     1801 cttatcaaaa agaagattat tccgatacgg aaattaagga gaagcaaggg gagttaaatc
     1861 gtatttatga tgagttttcc aagaaatacg gaattttaaa cagtaaggcg aataaaaaac
     1921 tgtttcgtga agacgctaat tattctttac tgtccacttt ggaaaagctg gataaagaag
     1981 gaaactttat agaaaaatcc gatatcttta caaaaagaac aataaaaaaa gcagtagcca
     2041 tagagcatac cgacaatctg acagaagcac ttatcctatc tatttctcaa aaagggaaag
     2101 tcaatttcga gtatatggaa aagctcactg aaaaaacaag aggagaaatc attgaaggat
     2161 taaagggaga aatattctta aatttagatg gatttgatcc aagtgatacg actccttttt
     2221 cttcagccat agacttggga gatttttcaa gatcttacgt aactgctgat gaatatttat
     2281 ctggaaatat cagagataaa atagaagtaa tagattcgta tataaagaat gtagaacatg
     2341 aatttgaaca aaatgaacag cttgaaaata ttgatgcaga tgtactgaaa cagggtagtg
     2401 agactttaaa aaaagaactg tccagtttaa attaccaaag acaaaagctg ctagaagtaa
     2461 tgccaaagga gcttgaggca agtgaaataa ccgttagaat gggagcaact tggatacctg
     2521 agaaagatta taagagcttt atgttccatc ttctaaaaac atcggcatct aatagatgga
     2581 atattgatat taaatatacc aattttacag gggagtacag agttgaaggt aaaagtatag
     2641 ataaaggaaa cgaccttgcc aatttcacat acggaacaag cagagtaagt gcatataaac
     2701 tgattgaaga tacattaaac cttagagata ccaatgtata tgatcaagtc attgatgaaa
     2761 acggaaagaa aagttctgta ctaaatcaaa aagaaacgat gcttgcaaga agtaaacagg
     2821 aaattatcaa agaagagttt aaaaattgga ttttcgatga tatagacaga agaacaaggc
     2881 ttgtaaaaga atacaatgag aaattcaatt cgataaggct tagagaatat gatggaagta
     2941 atttaacttt tgacggaatg aatcctgaaa tagagcttag acctcatcaa agagatgcga
     3001 ttgctagagg acttttcggt ggaaacaccc tacttgcaca tgaagttgga gctggaaaga
     3061 cttttgagat gataggaatt gctatggagt ctaaaaggct tggaatgagt aacaagtcaa
     3121 tgtttgtagt tccaaaccat attgtagaac agtttggtag agagtttaat gaactgtatc
     3181 cggcagcaaa tattctttgt gcaacagaaa aagactttac accagataaa agaaaaagat
     3241 tttgctcaag gattgcaacc ggtgattatg atgcggtaat tatagggcat tcgcagtttg
     3301 aaaagattcc aatttcaaag cagcgacagg agtatgaact tcaaagtcag attgatgaaa
     3361 ttatagattt tatcgaagaa tataaaagga atagagatca gaaattcacc gttaagcagc
     3421 ttgaaaaaac gaaaaaagga ctggaggcaa aactaaagaa attaaatgat gattatagaa
     3481 aagatgatgt cgtaaccttt gaagaattgg ggatagacaa gctatttgta gacgaagttc
     3541 atgcttttaa aaatttgtac gtttttacaa aaatgcgtaa tgtagcagga attacaacca
     3601 cagattctca aaaatcaagt gatatgctga tgaagtgcag atatatggat gaaattaccg
     3661 gtaataaggg tattgtattt gcgacaggaa cccctgtgag caattctatg gcagagcttt
     3721 ataccatgca gcgttatctc caatatgacg aacttaaaaa aatgcacttg caacactttg
     3781 attcttgggc atctactttt ggagaaactg ttacagcaat tgaacttaat cctgaaggga
     3841 acggatatcg aagcaagaca agatttgcaa aattttataa ccttccggaa ctgatgaata
     3901 tggtcaagca gtttatggat ataaagactg ctgatgtatt aaatcttccc gttccaaatg
     3961 ctcattatga aacgataaaa accaaaccga cagaagaaca aaaacaaatc cttgaaactt
     4021 tttctgagag agctgataag gttagaggaa aacaggtgga ttcctctgtc gataatatgc
     4081 ttctgattac taatgacgga aagaaaatgg cacttgacca aaggttaatt aatccattac
     4141 ttcctgatga tccgaacagt aaagtaaata cctgtgtaaa taatatattc agtatttggg
     4201 ataaatatag ggatgagaag tccacacaat tagttttttg tgatatgtca acaccatcaa
     4261 gtgaatttaa tatttatgat gatataaagg agaagctgac aaaaatgggg attcctaaaa
     4321 atgaaacaga gtttattcat aacgcaaaga acaacaaaga aaaagataag attttcgata
     4381 aggtacgaaa gggtgaaatt cgtgtgcttc tcggttcaac gcagaaaatg ggagcaggga
     4441 caaatgctca aaataaattg attgctaccc atgatctcga tgtaccctgg aggcctgcgg
     4501 atttggagca gagaaaagga agaattgtaa ggcaaggtaa tgaaaatgat gatgttcata
     4561 tctttcgtta tattacggaa aatacctttg atgcgtatct tttccaaaca cttgaaacca
     4621 agcaaactta tatatctcaa ataatgaatt caaagacacc tgtaagagta gcggaggata
     4681 ttgatgaagc tacattaaat tatgcggaga ttaaagcact tgcaacagga aatccgctta
     4741 ttcgtgaaaa aatggacctt gatgttgagg taagtaaact taaaatgctg gagtccaatt
     4801 ttaaatccaa cctatataaa atggaagata aggttgtaaa agtatatcca aaagaaatta
     4861 aaagtctaaa aga
//
LOCUS       DARYXW010000109         4849 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.110, whole genome shotgun sequence.
ACCESSION   DARYXW010000109 DARYXW010000000
VERSION     DARYXW010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4849)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4849)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4849
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.110"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(462..665)
                     /locus_tag="TV191_001748"
     CDS             complement(462..665)
                     /locus_tag="TV191_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class IIb bacteriocin, lactobin A/cerein 7B
                     family"
                     /protein_id="HEL1508229.1"
                     /translation="MKQYEDFQMLYELDLASVNGGKINWGSVAGHCAGGAIVTGAFSG
                     PLYVLGAGIGCIVGAGQAIINGL"
     gene            complement(682..939)
                     /locus_tag="TV191_001749"
     CDS             complement(682..939)
                     /locus_tag="TV191_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEL1508230.1"
                     /translation="MNTETINQFDVMNIEALATVEGGYSGKDCLKDMGGYMLIGAGSG
                     ALWGAPAGGIGVLPGAFVGAHVGAIGGGFACMGGMIGNRFN"
     gene            complement(1260..2627)
                     /gene="rlmD"
                     /locus_tag="TV191_001750"
     CDS             complement(1260..2627)
                     /gene="rlmD"
                     /locus_tag="TV191_001750"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEL1508231.1"
                     /translation="MNVKIKQKIPLKIKRMGINGEGIGFYKKTLVFVPGALKGEEVFC
                     QVTAVKRNFAEARLLVINKASKNRVKPACSIYETCGGCQIMHLAYPKQLYFKDDIIRQ
                     ALKKFKPKGYEEFEIRHTLGMAEPQHYRAKLQFQTRSFGGSVKAGLFSEGSHCLVAID
                     DCLVQDQLTQAIVNHVTQLLDRYRIPIYNERRVAGIRTVMVRRAQASDQVQLIFVSSK
                     EVRLAGLIAELTAAFPQIRTVALNINTSKTSDIYGAKTEILWGQETIQEEVLSHSFAL
                     SPRAFYQLNPTQTEVLYSQVVQALEPTAEEHIIDAYCGVGSIGLAVANKVRSVRGMDI
                     IPEAIADARKNAQALGFDNAYYETGKAEELIPSWYAEGYRADALIVDPPRTGLDDKLL
                     QTILHYQPAKMVYVSCNTSTLARDLVPLVQVYDVIYIQSVDMFPHTARTEAVVKLQKR
                     QKPQQ"
     gene            complement(2624..3592)
                     /locus_tag="TV191_001751"
     CDS             complement(2624..3592)
                     /locus_tag="TV191_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1508232.1"
                     /translation="MTEKDKKDRDKVVSLQHYRQADAEDDMLFGHETEFFSDDLEALL
                     NSMDNQLLSDLEHFAGDRAYDLIKYLAFDEDCQHQAWLASKPMGWVNLEERPYLSQKF
                     ELAMLYKQNGLYEKALHHLLEIHQYDEGDHLGTRYEILALYVLKSDFTMAEAFYDSKD
                     YHRGDLLMEVPLMVGALLAEREELADDILANLAETVPDFVAIVRQKAFPIDDILAAGA
                     LESYEPNSLSSIYLAFFNILPLLMTAQYYLQHYVQEFFEGAEGELTFLEELDLPLSKV
                     NLFNQYGIHTLEDFSAWTTQELLDIPGVGKQMIARLKRLGVIFSQE"
     gene            complement(3732..3914)
                     /locus_tag="TV191_001752"
     CDS             complement(3732..3914)
                     /locus_tag="TV191_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEL1508233.1"
                     /translation="MLTYDEFKQAVDCDYITGDTVMIVRKNGRIFDYVLPNEEIRDWE
                     VVIEERVEEVMRELDK"
     gene            complement(4110..4625)
                     /locus_tag="TV191_001753"
     CDS             complement(4110..4625)
                     /locus_tag="TV191_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508234.1"
                     /translation="MKSKKLVFGQIDLNMCRDFDLVQALDYDFKEKKLYNKGRGFAIV
                     LVSIQNLTFAIPLRSNIPKKYQLKYKLRDSKKYGCVEGLDIGKALVVEDPKYILNRTF
                     KLREQVDYFKIVDNDILIVNKLIKAIIDYNQAVANSDQHKLTDPKRFKFSTFPNYTDR
                     LKSITDADYLR"
BASE COUNT         1470 a         1113 c          762 g         1504 t
ORIGIN      
        1 actaatctct aataaactaa tgctatctag tcttagctag caataaccta gtgcttctaa
       61 caacaataat cagctcaaca atttttagca gctacctttt taaaaaaact gggataaaaa
      121 gatttctcag gtaagaaaaa tagagattca ccaaacagtg aatctctatt ttttgaactg
      181 aaactccttt tgtcccaaac tcataagatg tattgacttt atgagatgaa caatttgtta
      241 cacttgattt gatcatcggg gtttagaaaa aatagtgaaa agaatcctca taattcgtga
      301 aaaatataat ttctcaccca aaaatccaat tcaagattgt atttataaga agtagcatga
      361 ttaaagttat agaaattctt atcaacgctt cttctttttt aacaacacca aatatcaata
      421 gtataatcgg aactaaaact aatactacta ataatattgt tttataatcc attgataatg
      481 gcctgtcctg caccaacaat gcatcctatt cctgcaccca atacatacaa tggaccagag
      541 aaagcacctg taacgattgc tccacctgca caatgccctg caacagagcc ccaattaatt
      601 ttaccgccat ttacacttgc caaatcaagc tcatataaca tctgaaaatc ttcgtactgc
      661 ttcatggtat atactccttt cttagttaaa tctattacct atcattccac ccatgcatgc
      721 aaaacctccc ccaattgcac caacatgtgc accaacaaat gcacctggaa gtacgccaat
      781 ccctcctgct ggggcacccc acaaagcccc acttccagct cctattaaca tatatcctcc
      841 catgtcttta agacagtcct taccagaata tccaccttca acagttgcaa gagcctctat
      901 attcataaca tcaaattgat taatcgtttc tgtattcatt ttgaatacct ccataacata
      961 ttttttcttt atgtcgcgat cacgatttaa gtatagcatt ctagtatcat attttttcta
     1021 aaagtcttaa acggtcgttt tttcatcgta aacggtcatt ttcaatcgtt ttcaaccgtt
     1081 caagacaaaa ttaactacca ttcaggattt tcattggata aatagctatt ttttggctct
     1141 ttgccaaccc actaaagcta ttaataaaaa aataagacag tagtcacatt taggctactg
     1201 tctcttttat ctaaagcctt gatcggtaag aaaagagcca gtcttttcca actaatcgat
     1261 tattgttgtg gtttttgtcg cttttgtagc ttcactacag cctcggtcct tgctgtgtgt
     1321 ggaaacatgt caacagattg aatatatatc acatcataga cctgaaccaa gggtaccaga
     1381 tcacgagcca aggttgaggt attacaggag acataaacca ttttagctgg ctgatagtgt
     1441 aaaatcgttt gtaatagctt gtcatctagt cctgttcgag gtggatctac aatcaaggca
     1501 tcagctcggt agccttcagc gtaccagctt gggatcagtt cctctgcctt gccagtctca
     1561 taataagcat tgtcaaagcc caatgcctgc gcatttttcc tagcatcagc aattgcctct
     1621 ggaataatat ccataccacg aacagatctt actttgtttg caactgccag accaattgag
     1681 ccaacaccgc aataagcatc aataatatgc tcctcagctg tgggctcaag cgcctgaacc
     1741 acttgactat ataaaacctc tgtctgtgtg ggattaagct gataaaaggc tcttggcgac
     1801 agggcaaagc tatggctcaa aacctcctct tgaatggtct cctgacccca gagaatctca
     1861 gttttggcgc cataaatatc actcgttttt gaagtattga tgtttaaagc aacagtcctg
     1921 atttgtggaa atgcagcagt cagctcagca ataagacctg ccagcctcac ctctttactg
     1981 cttacaaaaa tcaactgaac ctgatcactg gcctgtgccc tacgaaccat aactgtacga
     2041 attccagcta ctctgcgttc attatagata ggaatcctat accgatcaag cagctgagtc
     2101 acatgattaa caatcgcctg tgttagctga tcctgaacca gacaatcatc aatggcaacc
     2161 aagcaatggc tcccttctga aaataagcct gccttgacgg agccaccaaa cgaacgcgtc
     2221 tgaaactgta attttgctcg gtaatgctgc ggctctgcca ttcctaaggt atgacgaatc
     2281 tcaaactctt catacccctt aggcttaaac ttttttaagg cctgccgaat gatgtcatcc
     2341 ttaaagtaga gctgcttagg ataggccaga tgcatgattt gacagcctcc acaggtctca
     2401 taaatggaac aggccggctt cacccggttt ttagaagcct tattaatcac caagagcctt
     2461 gcctcagcaa aattgcgctt aacagcagtc acttgacaaa aaacctcttc tcccttcaag
     2521 gctccgggaa caaagaccaa ggtcttttta taaaaaccaa ttccctcacc attaatcccc
     2581 attcgcttaa tcttaagcgg tattttttgc tttattttga cattcattcc tgactaaata
     2641 ttactcctaa tcgcttaagc cttgctatca tctgcttgcc aacacctgga atatcaagaa
     2701 gctcttgagt tgtccaggcc gaaaaatcct ccagagtatg aatcccatac tgattaaaca
     2761 aattgacctt acttaaagga agatcaagct cctctagaaa tgttagctcg ccttcagccc
     2821 cttcaaaaaa ttcctgaaca taatgctgca ggtaatattg tgcagtcatc aatagcggta
     2881 ggatattaaa aaaggcaagg taaatacttg ataagctgtt tggctcgtag ctctccaggg
     2941 caccagcagc taaaatatca tctatcggaa aggctttctg tctgacaatt gccacaaagt
     3001 ctggcaccgt ctcagcaagg ttagccaaaa tatcatcagc tagctcttct ctttcagcta
     3061 atagcgctcc aaccatcaaa ggaacctcca tcaacagatc tcctctatga taatccttac
     3121 tgtcataaaa agcctctgcc atcgtaaaat cagactttaa cacataaaga gctaagattt
     3181 cataccttgt ccctaagtga tccccttcat cgtattgatg aatttctaag aggtgatgta
     3241 aagctttttc ataaagacca ttttgcttat acagcatcgc cagctcaaat ttttgagaca
     3301 agtaaggtct ctcttcaaga ttcacccatc ccataggctt agaagcaagc caggcctgat
     3361 gctgacagtc ttcatcaaag gccaaatact tgattaagtc ataggctcta tctcctgcaa
     3421 agtgctccaa gtccgacaac aactggttat ccatgctgtt taaaagagcc tctaagtcat
     3481 cactgaaaaa ctctgtctca tgtccaaaga gcatatcatc ttctgcatca gcttggcgat
     3541 agtgctgtaa gctaacaacc ttatctctat cttttttatc tttttctgtc ataatgccct
     3601 ttcaatctat tgaccattta tactcttatt ttaccatttt tgttataatg agggtataga
     3661 taaaactcct aaaattgtgg ctttacaatg tcgttccccg acaattcccc gacttctgga
     3721 cgaggtcttt tttatttgtc taattctctc atcacctctt ccactctttc ctctatcaca
     3781 acctcccaat ctcttatctc ctcattcggc aacacataat caaaaatccg tccgtttttg
     3841 cgcacaatca taactgtgtc tcctgtgata tagtcacagt ctactgcttg cttaaactcg
     3901 tcgtatgtta acataaatac ctcctacctt attattcgta aaaagtctag tttaatggac
     3961 taattttaac aagtccgtta taacggatat gccaatgtgt gaatacatgt gtgtgaaaca
     4021 caaaaaaccg cccagaaata atctgagcgg ttgattttta ttttggctaa ttcttactat
     4081 ggtaattggt tcatgattgt gcgagggtgt caacgaagat aatcggcatc ggtaatgctt
     4141 tttaatctgt cggtatagtt tgggaatgta gagaatttga aacgtttagg atctgttaat
     4201 ttatgttgat cactattagc tacagcttga ttataatcta tgatagcctt tatcaacttg
     4261 ttaacaataa gtatatcatt atcaacaatc ttaaaataat caacctgctc tcgtaatttg
     4321 aacgttctgt ttaaaatata ttttggatct tcaaccacta gagctttgcc aatatcaagc
     4381 ccctctacgc atccgtattt tttagagtct cttaatttat attttagttg atatttttta
     4441 ggaatattac ttctcaaagg gattgcaaaa gttagatttt ggatacttac caacacaatg
     4501 gcaaaacctc ggcctttgtt atatagcttc ttctctttaa aatcatagtc taaagcttgt
     4561 accaaatcga aatctcgaca catgtttaaa tcaatctgac cgaatactaa ttttttactc
     4621 ttcattattt gccttctaaa aataaaaaat cctaccaact gggtattggt aggacgcatt
     4681 gccaacggga tacttctgtt aacgagcgcg tccctccgcc ccctcattgc caaaatggcg
     4741 agagtttaac gacatggaaa ggtcggaaca tagagataat gcttttacta tttatgttca
     4801 tttacattat tacataatat gttgcattcg tcaaatatag aatctttaa
//
LOCUS       DARYXW010000110         4526 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.111, whole genome shotgun sequence.
ACCESSION   DARYXW010000110 DARYXW010000000
VERSION     DARYXW010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4526
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.111"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            92..1258
                     /locus_tag="TV191_001754"
     CDS             92..1258
                     /locus_tag="TV191_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEL1508235.1"
                     /translation="MKYNKTKYPNIFTYDTKKGKRYYVRRGYYLKGKKKEATKSNLKT
                     LQEARAALTEIEQKIENNDFAYNKNLTVDQYWEIYVDNRLKAGVWSPDTYVERTNIFK
                     NHIGPKFGNKKMNAINRIEYENYINNLLNTNSRSTVKHIYDVFSIMLNHAVKNKMLDD
                     NIIKFIDIGDSEIKPINKRRSMQEFKAWDKIARKMLDDYDYAMVRITYLGLRRSEVAG
                     IKLGNITFNDKDCAVVKIDESRTRGRKDGGGLKTAYSERYVYLDFETSQLLKKAIDTS
                     IKIAVCNDRILNKADFLFLGDDEKVKPSFVGKPIGSHYIYCLFKKINKNCDVNFTPHM
                     MRHFFATQGQIAGVPIEHMAAALGHSNNYMTSQYTHIKDEVSENVTAAFMGSIK"
     gene            1407..2183
                     /gene="recX"
                     /locus_tag="TV191_001755"
     CDS             1407..2183
                     /gene="recX"
                     /locus_tag="TV191_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEL1508236.1"
                     /translation="MKISQIEKKKHLYLIKLDNGDSLTVTEDTIVTFMLSKHMVIDSQ
                     QWEDIKSFAQFSYGKSKALGFIAFQQRSQKQVQDYLLKHQISPDLIPSIIDSLKQGKW
                     IDDQQYVDTYIRQNSLTGDKGPLLLKQKLMLKGIASQLIEPVLAQTDFSSIAQKAAEK
                     IYQKYQHKLPSKALTDKIIQGLLNKGFSYDLAKGIVSQLSLEQDSQHIEDLLDQEFDK
                     LLRKYSRRYDGYQLKQKLYQALYRKGYDSDDITTKLNDYF"
     gene            2416..2949
                     /locus_tag="TV191_001756"
     CDS             2416..2949
                     /locus_tag="TV191_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002949762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEL1508237.1"
                     /translation="MKLPKEGDFITIQSYKHDGRLHRTWRDTMVLKTTENALIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGVSYYCNLASPYLMDAEALKYI
                     DYDLDVKVFADGEKRLLDVDEYEMHKQEMHYSPNLDFILKENVKLLVDWINKEKGPFS
                     KAYVSIWYKRYLELKNR"
     gene            3199..3510
                     /locus_tag="TV191_001757"
     CDS             3199..3510
                     /locus_tag="TV191_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEL1508238.1"
                     /translation="MAFQATKGRYASFGVAVSLPPELIDTFWEIIDHYLKGVFPLNTV
                     LTFRLIKNKKNLSYEYIDQQAGLRIVFDYNTPFNAFYPKTLYIVNQQGIETILLPHEM
                     Y"
BASE COUNT         1610 a          893 c          777 g         1246 t
ORIGIN      
        1 tgtacctaaa attatatcac acaaaggtgg tgatgccaat atcctttcaa acgacctcgt
       61 ccaaaagtca aaaaaacgaa aggatttaag aatgaaatac aacaaaacaa aatacccaaa
      121 tatctttacc tacgatacaa agaaaggtaa acgctactac gtccgtaggg gttattactt
      181 aaaaggtaaa aagaaagagg ctacaaaaag caacttaaaa acgctacagg aagccagagc
      241 tgcacttact gaaattgagc aaaaaataga aaacaatgat tttgcttata acaaaaattt
      301 gacagttgat cagtactggg aaatatacgt tgataataga ttaaaagctg gagtgtggtc
      361 tcctgacaca tacgttgagc gcactaatat ctttaaaaat cacatcggcc caaagtttgg
      421 caataaaaaa atgaatgcta taaaccgtat agaatacgaa aactacatta acaatctgct
      481 caataccaac tcaagaagta cagtaaagca catatatgat gtttttagta ttatgttaaa
      541 tcatgctgtc aaaaataaaa tgctagacga taatatcatc aaatttattg acattggcga
      601 tagcgaaata aaacctatca acaaacgtag atcaatgcaa gagtttaaag cttgggataa
      661 aattgccaga aaaatgcttg atgattatga ctacgcaatg gttaggataa catatcttgg
      721 attgcgtaga agcgaggtag ctggcataaa attagggaat ataactttta atgataaaga
      781 ttgtgcagtc gtaaagatag acgaatcaag gaccagaggt agaaaagatg gcggaggcct
      841 aaagacagct tattcggaac gatatgtgta tttagatttc gagacatcac aactgctaaa
      901 aaaagccatt gatacatcta tcaaaatagc cgtgtgcaac gatcgcatct taaacaaggc
      961 tgatttccta tttttaggag acgacgaaaa agtaaagcca tcttttgtag gaaaaccaat
     1021 cggtagccac tacatctact gcttatttaa aaaaatcaat aaaaattgcg acgttaattt
     1081 tactccgcac atgatgaggc attttttcgc tacacagggc caaatagccg gtgtcccaat
     1141 tgagcatatg gcagcggctt taggtcattc aaataattac atgactagcc aatacaccca
     1201 cataaaagac gaggtaagtg aaaatgtcac agcagctttt atgggcagta taaaataaaa
     1261 attccccgac atagtccccg acaaaatatt actttttatg atttttgtta ctttttatga
     1321 ctaaacgaaa aaaactaaaa tgctgtaata tcaacgtttt aaaacaattt gcttgtatat
     1381 aaattttaaa acattataat gagggtatga aaatcagtca aattgaaaag aaaaagcatt
     1441 tatacctcat taagctagac aatggtgata gcctaacggt cacagaagat acgattgtca
     1501 catttatgct aagtaagcac atggtcatag acagccaaca atgggaggac atcaaaagct
     1561 tcgcacaatt ctcatatggt aaaagcaagg ccttaggttt tattgccttc caacaaagga
     1621 gccaaaagca agtccaagat tacctgctaa agcatcagat tagtcctgat ctcattccaa
     1681 gcattattga tagcctaaaa caaggcaaat ggattgatga tcagcaatac gttgacacct
     1741 atatacgcca aaatagcctt actggagaca agggaccatt acttctcaag caaaagctaa
     1801 tgctcaaggg aatagcctca caactcattg agcctgtcct agcacagact gatttttcct
     1861 ctatagcaca aaaggctgct gaaaaaatct accagaaata tcaacacaaa ttgccaagta
     1921 aggccttgac cgataaaatc atacaaggac ttcttaacaa gggcttttcc tatgaccttg
     1981 ccaaaggcat tgtcagtcaa ctaagccttg agcaggatag tcagcacatc gaagacctgc
     2041 ttgatcagga attcgacaag ctattacgaa aatacagtcg tcgctatgat ggctatcagt
     2101 tgaagcaaaa gctttaccaa gccctttacc gcaagggcta tgacagtgat gatattacca
     2161 ctaagctaaa tgactatttc taattctacc aaggctgctg caccgatttg acgcaaaagc
     2221 ttttagtcag caacaaagta gtcctattat gatcctgtag ctttgataat ggtttagcta
     2281 gctcctcaac tgaacatcag atttctaaaa acttctttaa gcatttgtca gatcatattg
     2341 tccaaaacag tgatttattt tctcaattat ggtaaactat agaggataag tttaattgta
     2401 gaaagttggt aaggcatgaa attacctaaa gaaggcgact ttattacaat tcaaagttat
     2461 aagcatgatg gtagattgca ccgaacctgg cgcgatacta tggtactaaa aacaactgaa
     2521 aatgctctga ttggagttaa tgatcacaca cttgttactg aaagcgacgg caggcgatgg
     2581 gtgacacgag agcctgcgat tgtttatttt cataaaaaat actggttcaa tattatagca
     2641 atgattcgag ataatggtgt ttcctattat tgcaaccttg caagtccata cctgatggac
     2701 gcagaagcgc tcaagtatat tgactatgat cttgatgtca aagtctttgc agatggtgaa
     2761 aagagattgc ttgatgtaga cgaatatgaa atgcacaagc aagaaatgca ttattcacct
     2821 aatctggatt ttattttaaa agagaatgtc aagctattag tcgactggat caataaagaa
     2881 aaaggaccat tttcaaaagc ctatgtcagt atttggtaca aacgttatct tgaactgaag
     2941 aatcgttagt cgttgtctag cactccaccg agggtgcttt atttaatcgc tagtatagta
     3001 tcacagctgt aaactggact ggcacttgca atctatcagc atttgttgtc aaattcatat
     3061 cattaaccac tatagcttgg cacaagcaca gacagcctat aacaccaagt agcaatcagt
     3121 atttatcatc agctgcctag ctagatcagg cattcaaatg acctcattat aacaccataa
     3181 caatagaaag gattgacaat ggcatttcaa gcaacaaaag gacgatacgc aagctttggc
     3241 gttgcagtca gccttccacc tgagctgatt gataccttct gggaaatcat tgaccattac
     3301 ctaaaagggg tgtttcccct caatactgtt ctcaccttca ggctaattaa aaataaaaaa
     3361 aacctttctt atgagtacat tgatcaacaa gctgggcttc ggattgtttt tgactataac
     3421 acaccattta acgcctttta ccccaaaacg ctctatatcg taaaccagca aggaattgaa
     3481 acgattttat tgcctcacga gatgtattga taagacctcg gacatcagct ataaagtcct
     3541 taccattcag ttgtagctca tcacatctgc tacaagcacc aacatgagat aatcttgtgt
     3601 ctttatccta gctctgaatg ctgtatagat attcagtcag ccagatacat agcaataaac
     3661 taagctcatg ccggtagaaa tagtcctaac atgagcttga cagttttttc attctgtaaa
     3721 tcattgctaa gcaaacacat cacctaagcc ctatttccta ttctgggaaa tggaaatctt
     3781 gatagaacat cccaatagtc ccatcatatt gagctatatc tatagggtct gacattttga
     3841 tatgttatca tctcatttta cgacaatcac tataggcttt atgacaattg gcatcattgt
     3901 cataacgatt aaattctata tgaccaaatg gctagtagga agctaattgc tttgtgttag
     3961 cctcacatag gatcttcaca taccccgtaa tcttaaaagt agttttaact gcacaaaact
     4021 tatagaacct aaaaatcaac aaacacactt taaagtacaa aaactttgcc ctccctcaaa
     4081 aagctctata atctctgtag tcggtaagcc cactgtggaa attatagttt ttttaattgt
     4141 acaaaaacaa gcccatatga cttatcatga aatgcaatca aaccatcatt agaaagactc
     4201 ataggaacac cttaagcatt actcagcatt taaaaaacaa tatccaaccg ttgactgttc
     4261 taaaagctca cccccacatc gttatcaatc ctaagcttga ttattcagtt ctcttatgcc
     4321 ctcactacaa aggaaacatg agcaaacaag acttccaaaa agcctctaaa atccctatct
     4381 tcgattgcca aagctttcca acactgcttc aactcaaaaa acactgcttt cagtggaaag
     4441 ccagttctaa agtgagcctt gctcaaactc cttttggttt taacatcaca aaaaagagca
     4501 ccaatctggt cctctttaga cgttag
//
LOCUS       DARYXW010000111         4499 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.112, whole genome shotgun sequence.
ACCESSION   DARYXW010000111 DARYXW010000000
VERSION     DARYXW010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4499
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.112"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            359..445
                     /locus_tag="TV191_001758"
     CDS             359..445
                     /locus_tag="TV191_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014868551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL1508239.1"
                     /translation="MQLMLGFGSFLLSLIGLVVIIVKMSNKK"
     gene            complement(793..3234)
                     /locus_tag="TV191_001759"
     CDS             complement(793..3234)
                     /locus_tag="TV191_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEL1508240.1"
                     /translation="MMIYSLKMQDIFNQAQFQAERFDSPYLETWHILLAMVAVDHSLA
                     AMVLSEFERKIRAEEYEAAAILAMGKSPKEVTSVQFKPQSKALSEILAFAHAICQVIN
                     EHEVGSEHVLFAILLNPDIMASRLLELAGYRLKDSGKGEPRFADLRKAIELNAGYSKE
                     TIKAIHELRKPKKSKSVGTFSEMMKPQSTAGELSDFTRDLTEMARQGLLEPVIGREKE
                     VSRMVQVLCRKTKNNPVLVGDAGVGKTALAYGLAQRIANGAIPYELQDMRVLELDMMS
                     VVAGTRFRGDFEERMNQLIDDIEADGKIILFVDELHTIMGSGSGIDSTLDAANILKPA
                     LSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPSVEDAYQILLGLKPSYEQY
                     HNVTISDTAVHTAVKLARRYLTSKQLPDSAIDLLDEASAMVQSMVKKTQPDFITPLDQ
                     ALLDGDMSKVSALLVKEDKQPKLKPTAVTEDDMLHTLSKLSGIPLEKLTQADSKKYLN
                     LEKELHKRVVGQEMAVSAIARAIRRNQSGIRTGRRPIGSFMFLGPTGVGKTELAKALA
                     ELLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYAVLLFD
                     EVEKAHPDIFNILLQVLDDGMLTDSRGCKVDFSNTIIIMTSNLGATALRDDKTVGFGA
                     KAIGHDHQAMEKRILEELKKAYRPEFINRIDEKVVFHSLTQENMRDVVKIMVKPLIAA
                     LAEKHISLKFQPSALKYLSEAGYDVEMGARPLRRTLQTEVEDRLAELMLSGELSSGQS
                     LKIGVSRGKLAFDIA"
     gene            complement(3234..3695)
                     /locus_tag="TV191_001760"
     CDS             complement(3234..3695)
                     /locus_tag="TV191_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEL1508241.1"
                     /translation="MPTKNTSDSIEEYIKELLAQSGIAEIKRSMLADSFQVVPSQINY
                     VIKTRFTESRGYEVESKRGGGGYIRIAKVHFSDKHHLIGTLIASIDDCLSEQAFTDSI
                     QLLFDEQLLTEREGNIILAVASNDVLGHQAPEIRARMLYRLLQRIDRKGSN"
     gene            complement(3865..4068)
                     /locus_tag="TV191_001761"
     CDS             complement(3865..4068)
                     /locus_tag="TV191_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEL1508242.1"
                     /translation="MAQGTVKWFNAEKGFGFISTENGQDVFAHFSAIQSDGFRSLDEG
                     QRVTFDVEDGQRGPQAVNITKLS"
BASE COUNT         1308 a         1063 c          802 g         1326 t
ORIGIN      
        1 gctttggtcg actttttcat gaaagttctc ctttcaattt ctaataatag tatacaataa
       61 atcagaagtc atagaataac catattcaat ttttatgtcg tattcgataa aaaatatacc
      121 atctcaacaa acaatcgctt aaaaacgatt ttagggtata tttcttccct gcaagcaaag
      181 gacacaaaaa agccatctga attttcaaca tcagacagct atttcgtatg actatggtat
      241 aatggtttct gcagaaaagt taaggcggtg gctctaattt ctgaaaggtg gtggtgctta
      301 tgactgtaag tgctaaaatc caaagagaaa ggagcgaata ttgtccgttt acgaggcaat
      361 gcaactcatg cttgggttcg gtagttttct actttcactc attggcttag ttgttattat
      421 cgtaaaaatg agcaataaaa aataaccgtc taactttagc gagtaacggt tattttttaa
      481 ctaaaaacaa gctaccgtct taaacggttc tgcattgggt agttgttttg agcaactgtc
      541 ctttttctat tttcattata tctcagctaa gaaaaatagt caaatgagat actattttgg
      601 cagctaaatt ggtagctaaa tcttcaaaat acctattttt cgctaaattc gattaaaatt
      661 aaatcctatc tgtctgctac gctttaaact ctcactctag tacttcatca ccatacgaca
      721 aaaagagcct gagaaacttt ttgtctcaga ctctctcaaa gctcttagct taatatcaag
      781 caaagtcatg cattaagcga tatcaaaagc tagttttcca cgtgatacac caatcttgag
      841 gctttgaccg cttgataact ctcctgacag cattaattct gctaacctgt cctcaacctc
      901 tgtttgcaag gtgcgacgaa gtgggcgagc gcccatttca acatcgtaac cagcttcaga
      961 caagtacttg agagctgatg gctggaactt aaggctaata tgcttttctg ccaaggctgc
     1021 aatcagcggc ttaaccataa ttttcaccac atcacgcatg ttttcctgtg ttaggctatg
     1081 gaagaccacc ttttcatcaa ttctgttgat aaattcaggc cgataagcct ttttcaattc
     1141 ctctaaaata cgcttttcca ttgcttgatg gtcatgaccg atcgctttag cgccaaatcc
     1201 aaccgtctta tcatctctta gagcagttgc tcctaggttg ctcgtcatga taataatcgt
     1261 gtttgaaaaa tcaaccttac atccacgact atctgttaac ataccatcat caaggacctg
     1321 cagcaggata ttaaagatgt ctgggtgagc cttttcaacc tcatcaaaaa gaagaacggc
     1381 ataaggctta tttctaacct tttcggttag ctctcctccc tcatcatagc caacatagcc
     1441 aggaggagcc ccattaagac gggaggctgc aaatttttcc atgtactcag acatatcaaa
     1501 acgaataagg gctgactcat catcaaagag taattcggcc aaggcctttg ctagctctgt
     1561 ttttccgaca ccagttggac caagaaacat aaaggagcca atcggacgcc tgcctgtgcg
     1621 aatgcctgac tggttacgac gaatggctcg tgcaatagca gaaacagcca tttcctgacc
     1681 aacaacacgc ttatgcaatt ccttttccag attcaggtat tttttactat ccgcctgagt
     1741 tagtttttct aggggaatac ctgatagctt gcttaaggtg tgtaacatat catcttcagt
     1801 aactgctgtt ggttttagct ttggttgctt atcctctttg actaaaaggg ctgacacctt
     1861 gctcatatca ccatcaagca gggcttgatc aagcggtgtt ataaagtcag gctgcgtctt
     1921 tttaaccata ctttgcacca tcgcactggc ttcatcaagc agatcaatcg ctgagtctgg
     1981 aagctgctta cttgtcaaat agcgccgagc cagcttcaca gcagtatgga cagctgtatc
     2041 agagattgtt acattatggt actgttcata ggaaggcttc aagccaagca aaatctgata
     2101 agcgtcctca acactaggct cctcaatcaa tatcttggca aagcgacgag aaagggctgc
     2161 gtccttttca atgtgctttt gatattcctc ttgagttgta gcgccaacca tatgcagggt
     2221 accgcgagaa agggctggct ttagaatatt agcggcatca agtgtgctgt caataccact
     2281 tcctgatccc ataatggtat gtagctcatc gacaaacaaa atgatcttac catctgcttc
     2341 aatatcgtca atgagttgat tcatgcgctc ttcaaaatcc ccacgaaaac gggtacctgc
     2401 aaccacactc atcatgtcaa gctccaagac acgcatgtct tgtaattcat aaggaatggc
     2461 tccattagca attcgctgcg ctaagccata agctagagca gtttttccga cacccgcatc
     2521 accaacaaga acaggattat ttttcgtctt acgacaaagc acctgaacca tacgtgacac
     2581 ctctttttct cgtccgatga ctggctctaa taagccctgt cttgccatct ctgtcaggtc
     2641 tcttgtaaag tctgatagct caccagctgt actctgtggc ttcatcattt cagaaaaggt
     2701 gcctactgat ttactctttt taggcttacg caactcatga atcgccttaa tagtttcctt
     2761 gctatagccg gcatttagct caatagcctt acgtaaatcc gcaaacctag gctctccctt
     2821 gccagaatcc ttgagcctgt agcctgccaa ttctaacaga cgactggcca taatatccgg
     2881 attgagcaaa atagcaaaga gtacatgctc tgagccaacc tcatgctcat tgataacctg
     2941 acagatagca tgagcaaatg ctagtatttc tgataaggcc ttggattgtg gcttgaattg
     3001 gacagaagtc acctctttgg gactttttcc catggctaaa atagcagcag cctcatactc
     3061 ttcagcccta atctttcgtt caaattcgct taacaccatg gccgctaagg aatggtcaac
     3121 agctaccata gctaataaaa tatgccaggt ctcaaggtaa ggactatcaa agcgctctgc
     3181 ttgaaattga gcctgattaa aaatgtcttg catctttaat gaataaatca tcactaattg
     3241 cttccctttc tatcaattcg ttgcaatagg cgataaagca tacgagcacg aatttctggt
     3301 gcttgatgtc ccaaaacatc attagaagct acagctaaga taatgtttcc ttcgcgctct
     3361 gttaacagtt gctcatcaaa aagcagctga atcgaatctg taaaggcctg ctcgcttaaa
     3421 caatcatcaa tagaagcgat caacgtacca atcaggtggt gcttatccga aaaatgaacc
     3481 ttagcaatac gaatgtagcc accaccacca cgcttacttt ctacctcata gcctctgctt
     3541 tctgtaaaac gggtcttgat cacataatta atctggcttg gtactacttg aaaggaatcc
     3601 gccagcatgg agcgcttgat ctctgcgatt cctgattggg ctaacaattc tttgatatat
     3661 tcttcgatac tatcggaagt attttttgtt ggcatgccgt cactcctttg ctaaaacgat
     3721 tcatttgctg ctttaagcct ttatttgact aaaactgact aacattatat caaatagcag
     3781 tcactaaaag caaatggaaa tcactagaat gtaaaaggac aggtgctatc aacaacaccc
     3841 atcccctatt atctgctcac tagattaaga caatttagtg atatttactg cctgaggacc
     3901 gcgctgtccg tcttcaacat caaacgtcac cctttgtccc tcgtctaacg atctaaagcc
     3961 gtcagactgg attgctgaaa aatgtgcaaa aacatcttga ccattttcag ttgaaataaa
     4021 gccaaagccc ttttcagcat taaaccactt gactgtacct tgtgccatag tcatccactt
     4081 cctttctata acgcatttgt aaacatagag agaaataaag atgccaaaac acaactacta
     4141 attcaaaaac taatttactc gctcagtgta acacgaatgg cagccactgt caacacatac
     4201 ccctcacaat gacagctttt ctactccacc tgctaaaatg taaaaaagca aagtcatgct
     4261 gaccttgctt taacaatcta aggcggtaga cggattttag atgcattgat atcagtgctt
     4321 tagagtaact ttgaccgact tttgaccgac cgccaatcta actccctcag cacattttct
     4381 actttttcct cggtcaccac ttcccaaggc tgcactttct cccctggcaa cacataatca
     4441 aatatctgtc cgtttttacg cacaatcgct actgtgtctc ctgttatata tccgtcatc
//
LOCUS       DARYXW010000112         4074 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.113, whole genome shotgun sequence.
ACCESSION   DARYXW010000112 DARYXW010000000
VERSION     DARYXW010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4074
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.113"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            48..1760
                     /locus_tag="TV191_001762"
     CDS             48..1760
                     /locus_tag="TV191_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HEL1508243.1"
                     /translation="MQTLVISEKPSVAISISKVLGATKKKDGYNEGNGYRVSWCVGHL
                     IQMANPDAYDEKYAKWDMADLPIIPKDYKYEVAKATKKQFNILKKLMNDKEIDTVINA
                     CDAGREGESIFRLVYNQVNCKKKMKRLWISSMEDSAIKEGFDHLKDGKKYDNLFESAQ
                     ARAIADWLVGMNISRLYSCLYNQNYSVGRVQTPTLAMIVKRDDEIANFKKEKYYTVEL
                     SMDGFILSTDRIDDKVAAEQLINLVGDKIEITDVIQNEKITKPDLPFDLTTLQRECNK
                     YFGYSAKQTLDYAQSLYEKKLITYPRTDSRCLTEDMITSMINNILGQNDFDTGRIKVI
                     FNSSKVTDHHAIIPTVSSMSEDLLSIPESEAKVYGLIFNKLHASVGYPLIENTTKIVV
                     TFDGFKFTSSGKVIKDEGFTKYLKEYKTKKNEDIELPNVNIGDSLKIKDKEIKEKYTQ
                     PPKHFTENTLLKSMETAGNDALKKGIEVERKGIGTPATRAGIIENLIYKGFIQRDKKN
                     LVATHKGISLITIVADNFKSAETTAKWEMELSDISQGKSSKEEFLRRVEAEIRNELSR
                     YKKD"
     gene            1764..2315
                     /locus_tag="TV191_001763"
     CDS             1764..2315
                     /locus_tag="TV191_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEL1508244.1"
                     /translation="MFDTLIKFSKDREKLDFYATDKRAIHELLKREQFLSPIYEPACG
                     MGHIGKVLEEYGYKVKATDICYRGYGEEREVDFFTVTENILDIVTNPPYFCASEFLRH
                     ALEISGPKVKIAMLFRLAFLEGQSRYELFRKYPPKRVYVFSKRLNCAKNGEFEKYKSS
                     AIAFAWFIWEVGYKGITELRWIR"
     gene            2357..3103
                     /locus_tag="TV191_001764"
     CDS             2357..3103
                     /locus_tag="TV191_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1508245.1"
                     /translation="MDKNEVLQSQENQTKEVMQEIKEEYTKTADFLEEHINQQLVIAK
                     EMKEEMQNKDFDVNIKELKALKEEITGLKAEIKRLNEMENITFGSLIIRDIKSVGNTL
                     INLQEKAVGSIKHLYDNMKHQLSYNLTKAQEKFVQMKIGIVKGLVNSMQDFIKDQQKK
                     LDSCLAKLDNLSKEIQKDEEKLEKGNLNKEKTLIKKREQSIEEKESQKEKMEKKPSVL
                     KKLKENQQKIKQEEKNKDIKALKKDKGMEL"
     gene            3120..>4074
                     /locus_tag="TV191_001765"
     CDS             3120..>4074
                     /locus_tag="TV191_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508246.1"
                     /translation="MNDLIKNYENIPDEMKKEKRWCLYKIIQRDGKNTKLPLMPNKEP
                     AKSNDKATWNSYEDCIMALKHNVGEGLGFFLGDGYIGIDIDKVSDDIMEYNTNHHVSS
                     MTADFLREVSTYAEISPSKTGLHFIGKGEVPGERKRYKNLEIYDKDRFFTVTGNVIKD
                     RDRSKIESIDSELKPLYEKYMPKTNKISAENKRSPTVTSYNGDQDILEKLFDRGYFSY
                     AGEDLRQIYYGNYERYFNSQSEADFFMLQRLLYYTGNVEMAISFMESSGLKREKWYKR
                     RGNTDYIHYIADKAISSINQFYDWEKVYTSKEKIEEKRYENK"
BASE COUNT         1644 a          504 c          856 g         1070 t
ORIGIN      
        1 atgcaaactc tgattgtctt ttttcatgta gaaaaaagga ggaatttatg caaacactgg
       61 tgataagtga aaaaccgagt gttgcaataa gcatatcaaa ggtgcttgga gcaacaaaaa
      121 agaaagacgg atataatgag ggaaatggat atagggtaag ttggtgtgtt ggtcatttaa
      181 ttcagatggc aaatccggat gcttatgatg aaaagtatgc caagtgggat atggctgatt
      241 taccgattat tcccaaggac tataagtatg aagtagcaaa ggcaaccaag aagcaattca
      301 acatccttaa aaagctgatg aatgataaag aaattgatac ggttataaat gcttgcgatg
      361 caggtcgtga gggagagagc atttttagac ttgtttataa tcaagtgaat tgtaaaaaga
      421 aaatgaaacg cctttggatt tcatctatgg aagatagtgc gattaaagag ggttttgatc
      481 atctaaaaga cggaaagaaa tatgacaatc tctttgaatc ggcacaggca agagccattg
      541 cagattggtt agtcggaatg aatattagta gactttattc ctgcttatat aatcaaaatt
      601 actctgtcgg tagggtgcag acgccaactc ttgccatgat tgtaaaacga gatgacgaga
      661 tagcaaactt taaaaaagaa aaatattata ctgtagagct atctatggac ggttttatac
      721 tttccacaga cagaattgat gataaggtag cagcagagca gctaatcaat ttagttggtg
      781 ataagattga aattaccgat gtcattcaaa atgaaaagat tacaaagccg gatttacctt
      841 ttgacctgac aacacttcaa agagagtgca ataaatattt tggatactca gctaagcaga
      901 ctcttgatta tgctcaaagt ctgtatgaga agaaacttat tacctatcca agaacagaca
      961 gtagatgcct tactgaagat atgattacaa gtatgataaa taacatattg ggacaaaatg
     1021 actttgatac agggcgtatt aaggtcattt ttaattcaag caaggtaacg gatcatcatg
     1081 ctattatacc gacagtaagt tcaatgagtg aagatttatt gagtattccg gagagtgaag
     1141 caaaagtgta tggacttatt tttaataagt tacacgcaag tgtgggctat cctttaatcg
     1201 agaatacaac aaagattgta gtgacttttg acggctttaa atttacaagt tccggaaaag
     1261 taattaagga tgaggggttt actaagtatt taaaggaata taagacgaaa aagaatgaag
     1321 atatagaact tccaaatgta aatataggtg atagtcttaa aatcaaggat aaagaaatca
     1381 aagaaaaata tacgcaacct ccaaaacatt ttacggaaaa caccttatta aaaagcatgg
     1441 aaacagcagg aaatgacgct ttaaaaaaag gtattgaggt tgaaagaaag ggtattggca
     1501 cacccgcaac tcgtgcaggg attatagaaa atctaattta caaaggcttt attcaaagag
     1561 ataagaaaaa tcttgtagct acacataaag gaattagtct tataacaatt gttgcagaca
     1621 actttaaatc tgctgaaaca actgcaaagt gggaaatgga gttgtctgat atttctcaag
     1681 ggaaatcttc aaaggaagaa tttttaagaa gagtagaagc tgagataaga aatgaattat
     1741 cccgttataa aaaggattag tctatgtttg atactctaat aaaatttagt aaagacagag
     1801 aaaaattgga tttttatgcc acagataaaa gggcaattca tgaactttta aaaagagagc
     1861 agtttctatc tcctatttat gagccggctt gtggaatggg gcatatcgga aaagttctgg
     1921 aagaatacgg ttataaggta aaagctacag atatttgtta taggggatat ggagaagaaa
     1981 gagaagttga tttttttaca gtaacagaaa atatattgga tatagtaacc aatccaccat
     2041 atttttgtgc aagtgagttt ttaaggcacg ctcttgaaat atcaggacct aaagtaaaga
     2101 tagcaatgct atttcggttg gcttttttgg aaggtcaatc aagatatgaa ttatttagga
     2161 aatatcctcc aaagagagta tatgtatttt ccaaaaggct taattgtgca aaaaacggag
     2221 aatttgagaa atacaaaagc agtgctattg cctttgcctg gtttatatgg gaggtgggat
     2281 acaaaggtat tacggagtta aggtggatta gataaaagga tggaataaaa caactgaaaa
     2341 aacgaaggag gatagtatgg ataagaatga agtattacaa tcacaggaaa atcagacaaa
     2401 ggaagttatg caggagatta aagaggaata taccaaaaca gctgactttt tagaagaaca
     2461 tataaatcag cagcttgtga ttgctaagga aatgaaagaa gagatgcaaa ataaggactt
     2521 tgatgtaaat atcaaagaat tgaaagcact caaagaagaa atcaccggat taaaagctga
     2581 aattaaacga ttaaacgaaa tggaaaatat aacttttggt tcattgatta taagagatat
     2641 caaatctgta ggaaataccc ttatcaattt acaggaaaaa gcggtaggaa gtattaaaca
     2701 tctgtatgat aatatgaaac atcagctttc ctataacctt accaaagcac aggaaaaatt
     2761 tgtacagatg aaaataggaa ttgtaaaagg attggtaaat tccatgcagg attttatcaa
     2821 ggatcaacaa aagaaactgg atagttgctt agcaaaactt gataatctat ctaaagaaat
     2881 tcaaaaagat gaagaaaaac tggaaaaagg caatctgaat aaagagaaaa ccctgataaa
     2941 aaaaagggaa caaagcatag aggaaaaaga aagtcaaaag gaaaagatgg agaaaaaacc
     3001 gtctgtgcta aaaaaattaa aggaaaatca gcaaaaaatc aagcaggaag aaaagaataa
     3061 agatataaag gcacttaaaa aagataaggg aatggaacta taaaaaagag gtggtagtta
     3121 tgaatgacct cataaaaaac tatgaaaata ttcctgatga gatgaaaaaa gagaagcgtt
     3181 ggtgcctata taaaatcatt caaagagacg ggaagaacac gaaacttcca ctaatgccaa
     3241 ataaagagcc ggcaaaatca aatgataaag ctacatggaa tagctatgag gattgtatca
     3301 tggcattaaa acataatgtt ggcgaagggc ttggcttttt cttaggagat ggatacattg
     3361 gaatagatat tgataaagta agtgatgaca ttatggagta caatacgaat catcatgtaa
     3421 gctctatgac ggctgatttt ttaagagaag tttccaccta tgctgagatt tctccatcga
     3481 aaacaggact acattttatt ggaaaaggag aggtgccggg agaaagaaaa agatataaaa
     3541 atcttgaaat ttatgataag gataggtttt ttacagttac cggtaatgtt ataaaggata
     3601 gagataggag caaaatagaa agtattgaca gtgagctaaa gcccttatat gaaaaatata
     3661 tgccaaagac aaataaaatt agtgctgaaa ataaaagaag tccaacggtt acttcttaca
     3721 atggggatca ggacatatta gaaaagttat ttgacagggg atatttttca tatgcaggag
     3781 aagatttaag acaaatttac tatggtaatt atgaacgcta ttttaacagc caatcggagg
     3841 ctgatttttt tatgctacaa aggctgcttt actatacagg aaatgtagaa atggcaatat
     3901 catttatgga aagtagcgga ctgaaaagag aaaaatggta taaaagacga ggcaataccg
     3961 attatatcca ctatattgca gataaggcga taagctctat caatcaattt tatgattggg
     4021 aaaaagtata tacatcaaag gaaaaaatag aagaaaaaag atatgaaaat aaga
//
LOCUS       DARYXW010000113         4072 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.114, whole genome shotgun sequence.
ACCESSION   DARYXW010000113 DARYXW010000000
VERSION     DARYXW010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4072)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4072)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4072
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.114"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            120..401
                     /locus_tag="TV191_001766"
     CDS             120..401
                     /locus_tag="TV191_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508247.1"
                     /translation="MKITKALCVAGAVAVLALAPISSSPAPTQTVFAATRGTEEYCHN
                     GWCSFLDEHGEWNTKREGESNSPLQRGSWWDWISYWSGYIWYSVYNWFR"
     gene            complement(586..1041)
                     /locus_tag="TV191_001767"
     CDS             complement(586..1041)
                     /locus_tag="TV191_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1694 domain-containing protein"
                     /protein_id="HEL1508248.1"
                     /translation="MDSLDTRLLKGASGENRFDPDQQRYYLGTYAERIVLALPLTEVD
                     HEKAKGYITAQLPHLKEAYFPLSFKLSSEFGSAYQMYYMKLAQQNALSATIVDEKGAV
                     SPFALIIHSDHAITKEETNLKAILDKPSDNKPAEQTKTKGKSLWQRLFH"
     gene            1272..2579
                     /gene="eno"
                     /locus_tag="TV191_001768"
     CDS             1272..2579
                     /gene="eno"
                     /locus_tag="TV191_001768"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEL1508249.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYLGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYTYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMIMPVGAPTFKEGLRWGAEVFHALKKILKARGLVTAVGDEGGFAPKFEGTEDG
                     VETILKAIEAAGYEAGENGIMIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQI
                     DYLEELVNKYPIITIEDGMDENDWEGWKALTERLGKRVQLVGDDFFVTNTEYLARGIK
                     EGAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAG
                     QIKTGSLSRTDRIAKYNQLLRIEDQLGEVAQYKGIKSFYNLKK"
     gene            complement(2715..2951)
                     /locus_tag="TV191_001769"
                     /pseudo
     CDS             complement(2715..2951)
                     /locus_tag="TV191_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400084.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            3160..3381
                     /locus_tag="TV191_001770"
     CDS             3160..3381
                     /locus_tag="TV191_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation repressor RelB"
                     /protein_id="HEL1508250.1"
                     /translation="MSTVTIRLNQEEEIFFKSYAQLTGQSLSSLFKKALERDIEDEYD
                     LKIYHQAYAEYKADPETISHADFKKELGL"
     gene            3383..3643
                     /locus_tag="TV191_001771"
     CDS             3383..3643
                     /locus_tag="TV191_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002998538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEL1508251.1"
                     /translation="MYRIEYSKKAQKQIKKVDKQIQRLLFAWIDKYLEGTDNPRANGK
                     GLTGNHANEWRYRIGDYRLICDIQDDKMVVLALEFGHRKDIY"
BASE COUNT         1232 a          722 c          902 g         1216 t
ORIGIN      
        1 gaaacctgac gagtaactat ttatggctat caatcagcat gttacactct ttttggaagg
       61 cctagcaatc actgactgtg aggttaacca aagaaaataa gatgttaagg agaatatcaa
      121 tgaaaataac taaagcattg tgtgtagcag gtgctgttgc agtcctagcc ttggcaccaa
      181 tcagctcaag tcctgcacca acacagactg tatttgctgc tacacgtggt actgaagagt
      241 actgtcataa tgggtggtgc agttttcttg atgaacatgg tgagtggaac acgaaacgtg
      301 agggcgaatc taatagtccc ctacagcgag gttcatggtg ggattggatt tcttattggt
      361 ctggttatat atggtattct gtatataact ggtttaggta acctctcaac gccactgcta
      421 ccatactgat aaatccctta gactattcta agggattttt actgcaaaaa gcacataggg
      481 acaaggcaat acaagctcca gcctgttctt agctccctat accggtaagg atcataacac
      541 tcagaactcc ggcagatgat tgcaggagct attggagagt gaggactagt gaaagagcct
      601 ctgccagagg gatttgccct tagtctttgt ttgttcagca ggcttattgt cagagggctt
      661 gtctagtata gccttgagat tggtttcctc tttggtgatg gcatgatcac tatgaatgat
      721 cagagcaaaa ggagagacag ctcctttctc atctacaata gtggcagata gagcgttttg
      781 ttgggccaat ttcatatagt acatttgata agcagagccg aattcagagg ataatttgaa
      841 tgacaagggg aaataagcct ctttgaggtg aggcagctgg gctgtgatgt agcctttagc
      901 cttttcatga tcaacctctg tcaagggaag cgctaagaca atcctttcag cataggtccc
      961 taaataatag cgttgttggt cggggtcaaa tcggttttct cctgaagctc cctttaagag
     1021 tcttgtatct aatgaatcca tacaatcctt tcaagcatgt gatactgtca ttatactatt
     1081 aactgcgcca aataccaatg ataaagcatt tactaggtat ttgatcggct tttggaagaa
     1141 gatgaaatca aagaaaaaca gcatgaaaac aactctctta tttcatgaaa ttagttttta
     1201 agttgcttaa gaccctagtt tgtggtatta ttaacatgta aaatattaaa actcataagg
     1261 agagtattat aatgtcaatt attactgatg tttacgctcg cgaagtcctt gactcacgcg
     1321 gtaacccaac acttgaagtg gaagtttata ctgaatcagg tgctttcgga cgtggtatgg
     1381 ttccttcagg agcttctact ggtgagcatg aagcagtaga acttcgtgat ggcgacaaat
     1441 ctcgttacct tggtcttggt actcaaaagg cagttgacaa cgttaacaac attatcgctg
     1501 aagcgatcat tggttatgat gttcgcgatc aacaagctat tgacagagcc atgatcgctc
     1561 ttgacggtac tccaaacaaa ggtaagcttg gtgctaatgc tattcttggt gtgtctatcg
     1621 ctgtagcgcg tgctgctgct gactaccttg aggtgccact ttacacttac cttggaggat
     1681 tcaatactaa ggttcttcca actcctatga tgaatattat caacggtggt tctcactcag
     1741 acgctccaat tgctttccaa gagttcatga ttatgccagt tggtgcacct accttcaaag
     1801 aaggtcttcg ttggggtgct gaggtattcc atgctcttaa gaaaatcctt aaagcgcgtg
     1861 gacttgttac tgctgttggt gacgaaggtg gatttgctcc taaatttgaa ggaactgaag
     1921 atggtgtaga aacaatcctt aaggctatcg aagctgctgg ctatgaagct ggtgaaaatg
     1981 gtatcatgat tggttttgac tgtgcgtcat cagaattcta cgataaagag cgcaaagtct
     2041 acgactacac taagtttgaa ggtgaaggcg ctgctgttcg tacatctgca gagcaaattg
     2101 actaccttga agaattggtt aacaaatacc caattatcac aatcgaagac ggtatggacg
     2161 aaaatgactg ggaaggctgg aaagcactta ctgagcgcct aggcaaacgt gttcaattgg
     2221 ttggtgatga cttcttcgtt acaaacactg aataccttgc tcgtggtatc aaagaaggtg
     2281 cagctaactc aatccttatc aaggttaacc aaatcggtac tttgactgaa acctttgaag
     2341 ctatcgaaat ggctaaggaa gctggctaca ctgctgttgt atcacaccgc tcaggtgaaa
     2401 ctgaagattc aacaatcgct gacatcgcag tggcaacaaa cgctggccaa atcaaaacag
     2461 gttcattgtc acgtactgac cgtatcgcta aatacaacca attgcttcgc atcgaagatc
     2521 aacttggtga agttgcacaa tacaaaggga tcaaatcatt ctacaacctt aaaaaataat
     2581 ttgattttag attaaaaggt tgacaagcct tgattttaaa gcattctagg actgtcctag
     2641 agtgctttta gttttagctt catgtcaact gtagtgggtg actgatagct aagcacgaga
     2701 ggagacgaag gtcgccttct ctttttcaat cggataaggc tagggaatcc ccaaatgtcg
     2761 atgaagggaa ttttagaagg tttctggaag tcgtatatga tttgtttccc tttgcagtgt
     2821 ctacacctag gagactgata gtccagtgta gcgctgactt cgatatgagt atcgtgctgg
     2881 atagtcttat tcaaggtgat attttgatct ttgattccga tgagtagtgt ggtatgatga
     2941 atctgttcca taagacactt tctaatgatg gtctggtcgc ttttcatgat aagccttatg
     3001 gaactttttg ggtactcaaa aagccctata atcttcataa tgaatttacc cattacagaa
     3061 attatagagc caatatttag aggattttag cctattggta gattgacagt ttcttaagat
     3121 tgtgttacaa tgtaacacaa agaaacgagg taaacgacta tgagtacagt tactatcaga
     3181 ttaaatcaag aagaagaaat atttttcaaa agttacgccc aactcacagg gcaaagttta
     3241 tcaagtctat ttaaaaaagc ccttgagcgg gatattgaag atgagtatga tttaaaaatc
     3301 tatcatcaag cctatgctga atataaagca gaccctgaga caattagcca tgctgatttt
     3361 aagaaagagc taggcttata acatgtaccg tatagagtat tctaaaaagg ctcaaaagca
     3421 gattaagaaa gtagataagc aaattcagag gttgctattt gcttggattg ataagtattt
     3481 agagggaaca gataacccac gcgcaaatgg caaaggtttg accggaaatc atgctaatga
     3541 gtggcgttat cgtattggtg attataggct tatttgtgat attcaagatg ataagatggt
     3601 tgttttagcg cttgagtttg ggcatcgtaa agatatttac taacgttgag gaagtaagat
     3661 ggtcaaaaat aatgcaattg gtagcaactg gaaagatgta agagctgagt tattcagcaa
     3721 ggaagaattt tagaaagtga tgctcgtatt gctattatgg acaagtatag ttaaaaagtg
     3781 tgcgttttta atctgtatga tgaagtaatt gataaagtaa caggtcaaaa ggctatcatt
     3841 gtctgtattg ctaataaatt ggtagatgat tgttatttaa tcgaaccgct aaaccattct
     3901 tacttaccag attggcgtga gataaatcag ttaattcgat ataaaaatta gcaccttatc
     3961 gggtgctaat tccttgcctg ctgaactcat aatttaatac cttttttact accccatatg
     4021 tttcccctaa ttatgtgtac ttgctagata taaggttaat tgggatagaa tt
//
LOCUS       DARYXW010000114         4069 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.115, whole genome shotgun sequence.
ACCESSION   DARYXW010000114 DARYXW010000000
VERSION     DARYXW010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4069)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4069)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4069
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.115"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            295..2097
                     /locus_tag="TV191_001772"
     CDS             295..2097
                     /locus_tag="TV191_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEL1508252.1"
                     /translation="MEVRGAMGNRQMKLKKYFLRFLLLLFAAIYIYFSSFAYQHSYLG
                     ISADYVNHSWVVSNIHNGGEASSSGLAVGDKILEIDHKSSQDNPLLNKLLIVEQATSM
                     TVLHQGIQRQIVFQKTHGSKKIFLMFSLLSIILFALSYGYSRRHEISRTSQRYYIFTF
                     LTSLLLVSIIPSSMGNVVARLILVIYITLFPFFIDMFWRAGTLQQESVKFSKFSKLII
                     TYSAATLCLLLYSKWFSVPLVITIYLVRGIFYVSFTFLVALFLITLVKDIKNNAFPRL
                     NIVLLVILCLLPLFIGYVFPLPYDIPFMYTIPLLLLPILAIINNLIINRLTTFRFHLP
                     VPILYVFIAMLGTVMIICLYLISDFMPKWLMISYSFLLTLCSIPIVKDLIFLNIRTGY
                     QLSNKSIFLAVEAEREDISIYLHDTIIQDIIYYKKRLENMDAVSKKAASDILDDVIFE
                     LRELCSNIYPLMIQELGLKNAILDIISKFQKKESVIINDNIQVEQLDFGQPINNFILR
                     SIRELINNSILHGNAKEIDIHIYNAEQYVVIKIVDGGHFKTARQTEAPHFGLTVIAEK
                     LALLGGQLLVDKHPTTIVMLIPRKQVNYDKNSNH"
     gene            2075..2674
                     /locus_tag="TV191_001773"
     CDS             2075..2674
                     /locus_tag="TV191_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1508253.1"
                     /translation="MIKIAIIDDHELVLQGLYDRLKKETHFEVVGAFTSYQDLLFCLK
                     YKSVDVLIIDLMLKDIHGFDLIAQIQQKCQTVPKMILISGFYEPLLHKRALDLGIKAF
                     LPKECSYDELISTVYNVAKGNQVIPDDLLQREESHLLTESEIEILKLISDEYSNEKIS
                     KKLYISRRTVDTHVSNICAKLNVTSRVGAVREAIRLKLI"
     gene            2782..3708
                     /locus_tag="TV191_001774"
     CDS             2782..3708
                     /locus_tag="TV191_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="avirulence protein"
                     /protein_id="HEL1508254.1"
                     /translation="MVDVDTLLGDHKTRYFGDGHKRTSYSINHDQNNQAYGTITQSGV
                     WSNKSDKVIQPHLSTLDGIVLASLAAERYLKEQYEACEDFYLSQFSVKSGRKPIEDLN
                     RVPIVVQKSSFNGDKASFSVSVLDMTVNLVFKRIDTYTAKDNKPAAEAKDYLSNHLKD
                     IHHHIYDVNFLDALDIADKCSIFCKANKAIRHVSNYKGISSQLSSSYSLLELLIIFSQ
                     MAEMLAYYADDIDRRYSETLWMKNVSAELVEPIPDGELALLGKITKNKLLDMKGKDWK
                     LFEMSGTDTQNRVRISSKIAHQLPSSEMLNNA"
     gene            3701..>4069
                     /locus_tag="TV191_001775"
     CDS             3701..>4069
                     /locus_tag="TV191_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEL1508255.1"
                     /translation="MLNKEIRLVISGTYSTGKTTTATALSIATGIPLINALSAREILT
                     DLYPGRRFQDMNATELMALGLKRFEERVREEAILYLQHTNFISDGSVLNEWIYGTVRM
                     KVGLNPGSGFIHRAAKAILGL"
BASE COUNT         1256 a          754 c          786 g         1273 t
ORIGIN      
        1 gcctgtgccc taaccctctc acctagacgc aaaaagaatc aaaacaaccg ttaataggaa
       61 atcatgaaag ccttctatga cagtcattgt tcataggagg ttttttacac caaatagacc
      121 ttctattggc ttttcatttg attcttaatg gatttttact gctaatttct gactcaccat
      181 cgttgcattc gtctcattat ttacaaattt atttggctaa tattgaaaat atgttatgat
      241 taatgtatta ttttggtatt atttttaaaa aatattattt tagaatggta aaaaatggag
      301 gtgagaggag caatgggtaa ccgtcaaatg aagctgaaaa aatacttcct caggttttta
      361 ttgttattat ttgctgcaat ctacatttat ttttcctctt ttgcctatca gcattcctac
      421 cttgggataa gtgctgatta tgttaatcat agctgggttg tcagcaatat ccataatggc
      481 ggggaggcta gctcctcagg actagctgtt ggggataaga ttttagagat agaccataaa
      541 agcagccagg acaatccttt gttaaataag ctgttaattg ttgagcaagc aacctcaatg
      601 actgttttgc accaaggcat acaaagacag attgtatttc aaaaaacaca tgggtctaaa
      661 aagatatttt taatgtttag cctgttatcc attatcttat ttgccttatc ctatggctat
      721 tctagaaggc atgagatcag tcggaccagt cagaggtatt acatctttac ctttttaaca
      781 tcgttattac tggtttcgat tattccatca agcatgggaa atgttgttgc ccgcttgatt
      841 ttagtgattt acatcacttt gtttcccttt tttattgata tgttttggag agcaggtaca
      901 ttgcaacagg aatctgttaa attttcaaaa ttttcaaaac tgatcatcac ctattctgct
      961 gcaaccctct gcttattgct atattctaag tggttttcgg tcccactcgt cattaccatt
     1021 tatttggttc gaggaatttt ctatgttagc tttacctttt tagtggcttt atttttaatc
     1081 accttggtta aagatatcaa aaacaatgct tttccaagac tcaatattgt cctgttggtt
     1141 atcctgtgct tgctgccatt gtttatcggc tatgtgtttc ctttgcctta cgatatccct
     1201 tttatgtaca cgatacccct attgctgctg ccgattttgg cgatcattaa taacctaatc
     1261 attaacaggc tcacgacctt tcgctttcat ttgccagttc caatcctcta tgtgttcatt
     1321 gctatgctag gcactgtgat gatcatttgc ttgtatctca tatcagactt tatgcctaag
     1381 tggttaatga ttagttatag ctttttacta accctgtgct caataccaat cgtaaaagac
     1441 ctgatttttt taaatatcag aacaggctac cagctgagca acaagtctat tttcctagca
     1501 gttgaggctg aaagagagga tatttcgatc tacctgcatg atacgatcat acaagacatt
     1561 atttattaca aaaaaaggct ggaaaatatg gacgccgtct caaaaaaggc tgcttcagat
     1621 attcttgatg atgtaatctt tgaattaaga gagctgtgct caaatattta tcccttgatg
     1681 attcaagagc taggcttaaa gaatgctatt ttagacatta tctctaaatt tcaaaaaaaa
     1741 gaatcggtga ttatcaacga caatatccaa gtggaacagc ttgattttgg gcagcccatt
     1801 aataatttta tcctcagatc aatacgagag ctgattaata atagcattct tcatggtaat
     1861 gctaaggaaa tagatataca catctacaat gctgagcaat acgttgtgat caagattgtt
     1921 gatggcggac attttaagac tgctcgtcag acagaagcgc ctcactttgg cttaactgtt
     1981 atcgctgaaa agttagcatt gctgggtggt caattgcttg ttgacaaaca ccctacgact
     2041 attgtcatgc tcattcctag aaagcaggtg aattatgata aaaatagcaa tcattgacga
     2101 ccacgaattg gtcttacaag gcctatatga tcggttaaaa aaggaaacac attttgaggt
     2161 tgtcggcgct tttaccagct accaagattt gttattttgc ttgaaatata agtctgttga
     2221 cgttttgatt attgatctca tgctaaagga tattcatggc tttgacttaa ttgcacaaat
     2281 ccagcagaaa tgtcagaccg tgccaaaaat gattttaatt tcaggatttt atgagccctt
     2341 gctgcacaaa agagccttgg atctaggcat aaaggccttt cttccaaagg aatgctccta
     2401 cgacgaatta attagcactg tctacaatgt tgcaaaggga aatcaagtga ttccagatga
     2461 cttgctgcag agggaagaaa gtcatctgct aaccgagtca gaaattgaga tattgaaatt
     2521 aatctcagat gaatactcga acgaaaaaat ctccaaaaag ctctatatca gcagaaggac
     2581 tgttgatacc catgtttcaa atatatgtgc taagctcaat gtaacaagcc gagttggagc
     2641 ggtgcgggag gctatcaggc tgaagctgat ctaacaagtc aaccaaaaaa ggcagacaga
     2701 tattcgtaaa ttacggatgt ctgttttttg atagtgtttt atcataagcc ttggttataa
     2761 ataagaaaag gagagaaact aatggttgat gtcgatacat tacttggtga ccacaaaaca
     2821 aggtattttg gtgatggtca caaaagaaca agctacagta taaatcatga ccaaaataac
     2881 caagcttacg gaacaattac ccaatcgggt gtgtggtcaa ataaatctga taaggtgatt
     2941 cagccacacc taagcacctt agatggcatt gttctagcca gtctagcagc tgaaagatat
     3001 ctaaaagagc aatatgaagc atgtgaagat ttttatttat ctcagttttc ggtcaaatca
     3061 ggcaggaagc ctattgaaga tttaaacagg gttccaattg ttgtccaaaa aagctctttc
     3121 aatggggata aggcaagctt ttcggtgtca gtgctggata tgactgttaa tctagtattt
     3181 aaacgcattg acacctatac agcaaaagac aacaaaccag ctgcagaggc aaaggattac
     3241 ttgtcaaatc atctaaagga cattcaccat catatctacg atgttaactt tttagacgca
     3301 ttagatatag cagataagtg ctctattttt tgtaaggcta ataaggcaat ccgccacgtc
     3361 agcaattata agggcatatc ctctcagcta tcaagcagct attccttatt agagctcttg
     3421 attattttct cacagatggc tgaaatgttg gcatattatg ctgatgatat tgatagaaga
     3481 tacagtgaaa ccttgtggat gaaaaatgta tcagccgagc tcgttgaacc gatacctgat
     3541 ggtgagctgg cccttttagg taaaattacc aaaaacaaat tacttgatat gaagggcaag
     3601 gactggaagc tgtttgaaat gtcaggtact gacacacaaa atcgagtgag aatttcaagt
     3661 aaaatagccc atcaattacc tagttcggag atgcttaaca atgcttaata aagaaattag
     3721 acttgtcata tcaggcacct attctactgg taagacaaca acagcaacgg ctctgtctat
     3781 tgcgacaggc atacctttga ttaatgcact ttcagccaga gagatcctga ccgacctgta
     3841 tccaggcaga cgctttcagg acatgaatgc cactgagcta atggctctag gattaaaaag
     3901 atttgaggag cgggtgcgcg aggaagccat tttatacctc cagcatacca actttatctc
     3961 agatggctcc gtgctaaatg aatggatcta tggaacagta cgaatgaagg taggcttaaa
     4021 tccgggctct ggcttcattc atcgagctgc aaaggccatc cttggactt
//
LOCUS       DARYXW010000115         3903 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.116, whole genome shotgun sequence.
ACCESSION   DARYXW010000115 DARYXW010000000
VERSION     DARYXW010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3903
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.116"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            <1..397
                     /locus_tag="TV191_001776"
     CDS             <1..397
                     /locus_tag="TV191_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1508256.1"
                     /translation="YVLTGGFLFTGFLLGLSFVLGAALIIYYKQYSEGYEDKKSYNIL
                     QEVGMSKQQVKKTINSQIVLVFFMPIAMAVLHFCVALVMLKQMLFLFGVLDTNLIYLV
                     SALTIAVIIVIYFTIYRITSKTYYNIIER"
     gene            441..1106
                     /locus_tag="TV191_001777"
     CDS             441..1106
                     /locus_tag="TV191_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1508257.1"
                     /translation="MIKAGKIYIVEDDAAILTPLKEHLSQNYQVLTVSNFRDIKQEVI
                     DYKPDIILMDITLPFFNGFYWTTEIRKTSTVPIVFISSSNDEMDTVMALNMGGDDFIS
                     KPFSLTILDAKIAAFLRRSQQFSSDDVTIDQFKLHFDGTLSNGTDSIHLSPTEHKILT
                     ILFTHPQQIVSKEDILARLWENESFIDQNTLNVNMTRLRKKISAIGFDCIHTVRGVGY
                     IIK"
     gene            1103..2080
                     /locus_tag="TV191_001778"
     CDS             1103..2080
                     /locus_tag="TV191_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1508258.1"
                     /translation="MIRAFFKEYYSWYIQYGVVMAGYLLIFWLYRLPLGYFKVTSLTI
                     LTLLILQGFGNYIRFKKKMKILQEFIYVKELDQLHSPSEQAYRSLIIKLKEAEAEVAL
                     YQLNNQKNTEALIKMWSHQMKLPLAAMSLMLQTNHIDIKDYQIQVLRLEHYLNNLLSY
                     LKFNQHSDDFRFQVCSVKQLVTSVIKKSSQTCIAKGISIAVDGDWQLSTDNKWLSFAL
                     TQIIDNAIKYSKPQGHIKVSIKEGSIFISDNGIGILEEDLPRLFEEGFTGYNGHEHQK
                     ATGLGLFMTKQILDKLNLNITISSQVDQGTLVVIQKKHSKQTKFSTSLL"
     gene            complement(2180..3250)
                     /gene="xerS"
                     /locus_tag="TV191_001779"
     CDS             complement(2180..3250)
                     /gene="xerS"
                     /locus_tag="TV191_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEL1508259.1"
                     /translation="MKRDLLLTKIEEYKNIMPWYVLDYYQSKLSVPYSFTTLYEYLKE
                     YKRFFEWLIDSDLSKAARIADVDLTTLEHLSKKDMEAFILYLRERPSLNIYSTKKGVS
                     QTTINRTLSALSSLYKYLTEEVENEHGEPYFYRNVMKKVATKKKRETLAARAENIKQK
                     LFLGDETMAFLDYVDKEYEYKLSNRAKASFRKNKERDLAIIALLLASGIRLSEAVNLD
                     LKDVNLNMMLVEVTRKGGKRDSVNVAAFAKPHLEAYLSVRKDRYQAEKQDVAFFLTAY
                     RGLPNRIDASSIEKMVGKYSEGFKIRVTPHKLRHTLATRLYDTTKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDKL"
     gene            complement(3407..3844)
                     /locus_tag="TV191_001780"
     CDS             complement(3407..3844)
                     /locus_tag="TV191_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEL1508260.1"
                     /translation="MLSKQKLSLEISHYLISGLLTTILYFVFRYVIYSWLHQATISAG
                     FANIIAIIAAFLMNDSYVFKQTSEKRLFRFAMFFLARVVTLGLDMLLAYLLVEKYPEV
                     IGSLVEHDSESINSVESILSQAIMISLNFIVSKYYIFKQHRSR"
BASE COUNT         1239 a          705 c          713 g         1246 t
ORIGIN      
        1 ctatgtccta accggtggct tcctttttac aggctttctt ttaggcttga gctttgtact
       61 tggggctgca ctgatcattt attacaagca atactctgaa ggctatgagg ataaaaaatc
      121 ttacaatatt cttcaagagg tcggcatgag caaacaacaa gtcaaaaaaa ccatcaattc
      181 ccaaattgta ttagtgttct ttatgcccat agctatggca gtcctacatt tttgtgtcgc
      241 tctggttatg cttaagcaaa tgctctttct ctttggcgtt ttagacacta atcttattta
      301 cctagttagt gcgctgacca ttgctgttat tatcgttatt tactttacta tttacaggat
      361 aacaagcaaa acctattaca atattattga aagataagac gagtggcgat ttttcgccac
      421 ttttttgata aaataatatt atgattaaag ctggaaaaat ttatattgtc gaagatgacg
      481 ctgctatctt aacaccctta aaagagcatc tgagtcagaa ctaccaggtt cttaccgtct
      541 ctaactttag agacattaag caagaggtga ttgattataa accggatatc atccttatgg
      601 acatcacctt accgtttttt aacggctttt actggacaac agaaattcgt aaaacgtcaa
      661 cagtgccaat tgtttttatc tcaagcagta atgatgagat ggatacggtc atggcactta
      721 atatgggggg agatgatttc atctctaaac ccttttctct aaccatttta gacgcaaaaa
      781 tcgcagcctt tttaagacgc tcacagcaat ttagcagtga tgatgtgacc atagatcaat
      841 ttaagctaca ttttgatggc accttatcta atggcacaga tagcattcat ttatcgccaa
      901 cagagcacaa aatcttaacg attttattta ctcacccgca gcaaattgtt tcaaaggagg
      961 atattctagc aaggctttgg gaaaacgaga gctttattga tcaaaacacg cttaatgtta
     1021 acatgacgcg tctacgcaaa aaaatatcag ctattggttt tgactgtatt cacacagtga
     1081 gaggagtagg ctatattatc aaatgataag agcatttttt aaggaatatt attcctggta
     1141 tatccagtat ggggttgtta tggctggtta tctgctgatc ttttggcttt ataggcttcc
     1201 tttaggctat tttaaagtga ctagcctaac catactaacc ttgctaatat tgcaaggttt
     1261 tggaaactat attaggttca aaaagaagat gaagatttta caagaattta tttatgtaaa
     1321 agaactagat cagctgcact cccctagcga acaagcctat aggtctttga ttattaagct
     1381 taaggaagca gaagcagagg tagcactgta ccaacttaac aaccaaaaga atacagaagc
     1441 actgattaaa atgtggtctc accaaatgaa gcttccccta gcggctatgt ccttaatgct
     1501 tcaaaccaat catattgata ttaaggatta tcagattcag gttctacgct tggagcatta
     1561 cctcaacaat ctattaagct atttgaagtt taaccagcat agtgatgatt ttcggtttca
     1621 ggtttgctct gtaaagcagc ttgtgacctc agttatcaaa aagtccagcc agacttgtat
     1681 cgctaagggg attagcattg cagttgatgg cgattggcaa ttgagcactg acaacaaatg
     1741 gctgtcattt gctctgacac aaatcattga caatgcaatc aaatattcta agccacaagg
     1801 ccacatcaaa gtcagcatta aggaaggcag tatttttata tcagataatg gtattggaat
     1861 actagaggaa gatttgccac gtctgtttga agaaggcttt actggctaca atggccatga
     1921 gcatcaaaag gcaactggtt taggcctctt tatgacaaag caaatccttg ataaattaaa
     1981 tttaaacata actatttcca gtcaagttga ccaaggaact ttagttgtaa ttcaaaaaaa
     2041 gcattctaaa cagaccaaat tctcgacttc tttgctgtaa aaaataacag ctataaatcc
     2101 ctataatagt gacaaagagg attaaaacat tgcaaaaaaa gactgaaagt acagattaca
     2161 taattttagt tatgtaaatt tataatttat ctagggcatt tttttgctca tcgttaacaa
     2221 tatgagtata gaggtctgta acttgggtcg aggcatgacc aagctgatga cttactagga
     2281 cctgtgactt tgtagtatca taaagtctcg ttgcaagcgt atggcgtagc ttatgaggag
     2341 ttacacgaat tttaaagcct tcagaatatt tacctaccat tttttcaatg cttgaggcat
     2401 ctatccgatt ggggagccca cgataggctg ttaaaaagaa ggctacatcc tgtttttctg
     2461 cttgatagcg gtcttttcga actgataaat aggcttctaa atgaggcttg gcaaaagcag
     2521 caacattgac cgaatctctc ttacctccct tacgggtaac ctcaaccagc atcatgttga
     2581 ggttgacatc cttaaggtct aggttaactg cctcggataa ccgaatacca gatgccagca
     2641 gtagggcgat aatggctagg tcgcgttctt tattttttcg gaaagaagcc tttgcccgat
     2701 ttgacagctt atattcatat tctttatcca catagtctaa aaatgccatc gtctcatcgc
     2761 ctaaaaaaag cttttgttta atattttcag ccctggctgc taaggtttct cttttctttt
     2821 tggttgccac ctttttcatg acatttcgat aaaaataagg ctctccatgc tcattttcaa
     2881 cctcctcagt aaggtattta tacaagctgg atagtgcaga aagggtacga ttaatggtgg
     2941 tttgcgatac ccccttttta gttgaataga tgttcaagga aggacgctca cgaagataga
     3001 gaataaaggc ttccatatcc tttttactca aatgctccag agtagtcaag tccacatcag
     3061 caatcctagc agcttttgat agatcagaat caattaacca ctcaaaaaag cgtttgtatt
     3121 ctttcaggta ttcgtacaag gtcgtaaagc tataaggaac agatagctta gattgataat
     3181 aatcaaggac ataccaaggc atgatgtttt tgtattcttc aattttagta agtagtaaat
     3241 cacgtttcat aataaattct cacaatgttt cgtcaacaaa tgaattatcc attggatatc
     3301 agactgatag tagtatatca catcttgggg tatttttcaa gaaaattata gtttttcgga
     3361 aagatataaa attatttaat agttattttg ctaagctaag gctgttttat ctgctacgat
     3421 gctgcttaaa aatatagtat ttactaacaa taaaattcaa gctaatcatt atggcttggc
     3481 tcaaaatgct ttcaacagaa ttaatgcttt cagaatcatg ttcaacaagg cttccaatga
     3541 cctctgggta tttttcgact aataaatagg ctaatagcat atctaagcct aatgttacta
     3601 ctctagctag gaaaaacatg gcaaatctaa acaagcgttt ttcagaagtt tgcttaaaaa
     3661 catagctatc gttcatcaag aaggcagcta tgatcgctat aatattggca aagcctgctg
     3721 atatggtggc ctgatgtaac catgaataga tgacataccg aaaaacaaaa taaagaatgg
     3781 ttgttagaag accagatatc aggtaatgac tgatttcaag tgataatttt tgtttgctaa
     3841 gcatttttct ttcctatgtg tatttatctt gactgttata ttttgatgga tctatataag
     3901 tat
//
LOCUS       DARYXW010000116         3863 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.117, whole genome shotgun sequence.
ACCESSION   DARYXW010000116 DARYXW010000000
VERSION     DARYXW010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3863
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.117"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(<1..736)
                     /locus_tag="TV191_001781"
     CDS             complement(<1..736)
                     /locus_tag="TV191_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Arm DNA-binding domain-containing protein"
                     /protein_id="HEL1508261.1"
                     /translation="MAKFRKRGDKWSYRIYYTDSQGNKREKSKGGFKTKALASAAAIK
                     VEAELNKDIDDISLYDFCKEWAKIYKRPHVVDKTWETYTKNLKHIKKYFGDIKLNNVT
                     HTFYQKTINEFAKKYAQETLEKLHYQIKGAVNVAVRDGLIKTNFAEGAIVKSQKEARA
                     KEFDFLEEDEYLNLIKVTSEKYQYVSYFTLYIIAVTGLRFAEATGITWSDIDFEKGFI
                     DINKSFDYSKTQEFKETKNEQSKRQIP"
     gene            complement(863..1138)
                     /locus_tag="TV191_001782"
     CDS             complement(863..1138)
                     /locus_tag="TV191_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEL1508262.1"
                     /translation="MRYKVLFTKKAKKQLKKLDRSTAKQLYQWIMTNLDGTDNPRRYG
                     KALQANRTGEWRYRLGNYRILAEIIDDEVVIEVFKIEHRSSVYKIKR"
     gene            complement(1128..1346)
                     /locus_tag="TV191_001783"
     CDS             complement(1128..1346)
                     /locus_tag="TV191_001783"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEL1508263.1"
                     /translation="MIAMTLNLEKDDAYIADYIKENNIDTSNLTVDQFLEIIEDAKDL
                     YELRKAKAEDDGTRFSMEDVAKELGFAL"
     gene            complement(1362..1883)
                     /locus_tag="TV191_001784"
                     /pseudo
     CDS             complement(1362..1883)
                     /locus_tag="TV191_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059208.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            2272..2478
                     /locus_tag="TV191_001785"
     CDS             2272..2478
                     /locus_tag="TV191_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1508264.1"
                     /translation="MLNIDKVRKEKGVAIVDMADFLGVRAQTVSDKLRGTYDFKFTEA
                     LALQQKFFPEYDLEYLFNKAVDTA"
     gene            2528..2683
                     /locus_tag="TV191_001786"
     CDS             2528..2683
                     /locus_tag="TV191_001786"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508265.1"
                     /translation="MVTKFSEEIKIVRTKSSVYVNSVLDVADKKDPASVVAVAELLKA
                     YKSLTEL"
     gene            complement(2684..2887)
                     /locus_tag="TV191_001787"
     CDS             complement(2684..2887)
                     /locus_tag="TV191_001787"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508266.1"
                     /translation="MKRYIIEQLANETDTITIMFTNGKQHTFCQVANECPDNPNIIEL
                     KLSDAQYIVLVNLDQVTYISHHS"
     gene            2947..3408
                     /locus_tag="TV191_001788"
     CDS             2947..3408
                     /locus_tag="TV191_001788"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508267.1"
                     /translation="MQANRIFYGKEKPTNAVAGDCWFRDNELMILKDNWEASVNNLKS
                     PKVIGEIEIDLEQHDVLLTARGNRPPLLMIDGIMLGGVSKVIIINELSESCAIVSLNE
                     YIKENLFPFDDFESLQRLFQKGHQKLSVRELCLEKRLGEHSYQDHRKSCDE"
     gene            3550..>3863
                     /locus_tag="TV191_001789"
     CDS             3550..>3863
                     /locus_tag="TV191_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001072522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antA/AntB antirepressor family protein"
                     /protein_id="HEL1508268.1"
                     /translation="MNQLINITLNENQEPVVSGRDLHKVLEIKTAYKDWFPRMAEYGF
                     EEGQDFSSFLSKSTGGRPSQDHVLKLDMAKEIAMLQRNEKSKEVRKYFIQVEKDFNSP
                     EK"
BASE COUNT         1170 a          706 c          714 g         1273 t
ORIGIN      
        1 tgggaatttg tctttttgat tgctcgtttt ttgtttcctt aaattcttga gtttttgagt
       61 aatcaaacga tttattaata tctataaatc ccttctcaaa gtctatatcg ctccaagtta
      121 tcccggtcgc ttcggcgaat cgtagtccag tcactgctat gatgtataaa gtaaaatagg
      181 aaacatactg gtatttctca ctcgttactt tgattagatt tagatattca tcttcttcaa
      241 ggaaatcaaa ttcttttgct ctagcttctt tttgagattt tacaatcgca ccttcggcaa
      301 aatttgtttt gataagccca tctctaactg ctacattaac agctcctttt atttgatagt
      361 ggagtttttc gagtgtttct tgggcatatt ttttggcaaa ttcgttgatt gttttttggt
      421 aaaaggtatg cgttacatta ttaagcttaa tatcaccaaa atattttttg atgtgcttaa
      481 gatttttagt gtaagtttcc caagttttat cgacaacatg cggacgtttg tagattttag
      541 cccattcctt gcaaaaatca taaagtgata tatcatcaat atctttattt agctcagcct
      601 cgactttaat cgcagctgca gaagccaatg cttttgtctt aaaaccacct ttggattttt
      661 cccttttgtt cccctgacta tctgtgtagt aaatacgata agaccacttg tcgccgcgtt
      721 ttctaaattt tgccattgtt aattacctca tttttatgtt aaaatgggta cagtaaagag
      781 acctactgcg aagcaggttt tttactatac aggatttgcc tcacgctcag actcgccaaa
      841 gtttgagagc gtggggcttt ttttaacgtt tgattttata gactgagctt cgatgctcta
      901 ttttaaaaac ttcgatgaca acttcgtcat caataatctc agctaaaata cgatagtttc
      961 ctaaacgata acgccactct cctgtacgat tagcttgtaa agcttttccg tatctccttg
     1021 ggttatctgt gccatcaagg ttagtcatta tccactgata gagttgttta gcagtagatc
     1081 tatctaattt tttgagttgt tttttggctt ttttagtaaa caatacttta taacgcaaaa
     1141 cctagctcct tcgctacatc ttccatgcta aatcgtgtcc catcgtcctc agccttagct
     1201 tttctcaatt cgtacaaatc tttagcatct tcaatgattt ccaaaaactg gtcaactgtt
     1261 agattggagg tgtcaatgtt attttctttg atgtaatctg cgatataagc atcgtctttt
     1321 tcaaggttta atgtcattgc aatcatagta tttttctcct tctatatttc tactggtgta
     1381 aagctgccga cgacatcata gattttgatg taagtatctt ctgctggcgg gtagtcgata
     1441 aagatatcat tgtatttttt attgagagat actaatctaa gcccgtcttc ctctgtgtat
     1501 acttttttaa aataggtctg tccgttatgc acaactatac atagctgacc ggcatatgct
     1561 gacatgcccc gatctacaat atagagcata tctccttgct cgtactttgg tagcatacta
     1621 tcgccccgca ctccaattgc atagtcgtag tgaggtggtt cttcgtcagt gtagacagta
     1681 tatgtgtcat attcatctgc ttcaaatcca cgaccaaagc cacttgcggc tgccgcgtaa
     1741 gttacgcctt gaaccgaaaa taattcttca tgcgtagaaa caactttatt ttgttcttcc
     1801 aattgctcct tggcaaagtc aaggactttt tcttgtctag gttgttctag ttggttgtag
     1861 atggacacta tttcagatgt attttttggg gcatctagca gagacgaaaa cacctcgggt
     1921 ctgataccta aagctgagca aatttttatg gcattctcga cgttagcatt cattattcct
     1981 cgctctaata tcgagcgaac cgttgagtaa ggcatgttgt tttcttctgc aaaagatttt
     2041 acagagctat aacgagaaag tataagatgt tttagatttt cttcattcat ggctgcctct
     2101 ctttctgatt tcattataac acacgatttt tcgtttgtct aacaaaaaaa cactaagaaa
     2161 tacgaatttt agtattgaca aacacgaaaa aaagtattaa acttgtatca agctcagatg
     2221 agcttaactt taaaaccaaa aacacgaaaa atcgtgttag aaaggagtta tatgttaaat
     2281 attgataaag tgcgaaaaga aaaaggcgta gcaatagtag acatggctga ttttcttggc
     2341 gtaagagctc aaacagtaag cgataaattg cgcgggactt acgattttaa atttactgag
     2401 gctttggcgt tgcaacaaaa atttttcccg gagtacgatt tagaatatct ttttaacaaa
     2461 gcagtagaca ctgcttaact ttaaaaccaa aaacacgaaa aatcgtgtta gaaaggagaa
     2521 aatcaatatg gtgacaaaat tttcagaaga aataaaaata gtaaggacga agtcttctgt
     2581 ttatgtaaac agcgtcttag acgttgcaga taaaaaagac cccgcgtctg ttgtagcagt
     2641 cgcagagctt ttaaaggcgt ataagtcgtt aacagaattg taatcaacta tggtgactta
     2701 tatacgtgac ttgatcgaga ttgaccaaaa cgatgtattg agcgtctgat agtttcagtt
     2761 caataatatt tggattatca gggcactcat ttgcaacttg gcagaatgtg tgttgcttac
     2821 catttgtgaa catgattgta atggtatcag tttcattcgc tagttgttcg ataatatatc
     2881 gtttcataca atcacctcct ttctgctcat attatagcag ttaaggacaa ctagagaaag
     2941 gacactatgc aagcaaatcg aattttttac ggaaaagaaa aaccaacaaa cgcagtagcg
     3001 ggcgattgct ggtttagaga taacgaatta atgatactca aggacaattg ggaagctagc
     3061 gtaaacaact taaagagccc taaagttatc ggagagatag aaatagacct agagcagcat
     3121 gatgtactgc tgacagccag agggaaccgt cctccactat taatgattga tgggataatg
     3181 ttgggcggag tatctaaggt aataattata aatgagttat ccgagtcttg cgcaattgtc
     3241 tctcttaatg agtatatcaa ggagaatttg ttcccttttg acgattttga atcacttcaa
     3301 aggttatttc aaaagggcca tcagaaatta tccgtacggg aactttgctt agaaaaacgt
     3361 ttaggtgagc attcttatca agaccatcga aaaagctgcg atgaatagta aaagttttct
     3421 taccgctcgc aagagctttc tcgtaatcct gagtcagtag tttaacagag agatctaatt
     3481 gatagtcgta cacttttgtt tatcctcctt ccactaggat aactacatta tacaacagaa
     3541 aggaacaaca tgaatcaact aataaacatc accctaaacg aaaatcaaga accagttgtc
     3601 agtggtcgtg atttacataa agtacttgaa atcaaaacag cttataaaga ttggtttcca
     3661 agaatggctg aatatggttt tgaagaaggt caggacttta gctcattttt gagcaaaagt
     3721 acaggaggtc gtcctagtca agaccacgtt ctaaaactag acatggcaaa agagattgct
     3781 atgttacagc gtaacgagaa atctaaagaa gtccgtaaat acttcatcca ggtcgagaaa
     3841 gacttcaaca gcccagagaa aat
//
LOCUS       DARYXW010000117         3844 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.118, whole genome shotgun sequence.
ACCESSION   DARYXW010000117 DARYXW010000000
VERSION     DARYXW010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3844)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3844)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3844
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.118"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            193..2670
                     /locus_tag="TV191_001790"
     CDS             193..2670
                     /locus_tag="TV191_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HEL1508269.1"
                     /translation="MNKDKRKKQEQRIKKDELELRKNRKELSELKKTGKKKTKSKTKG
                     KSSKKNGWFPFFMKEEKKETVQDTIPYKRMLKDGICQIEKNKFNKTIRFLDINYRLME
                     EIDQEGIFSEFSSFLNFFDSSVEVEFSYINSIGENEEINKLIDIKENIDDFNEIRNEY
                     RQMLLNQSSKGNNGLSKSMYITFTIEAEDLKQAKSRLERMEMDVLNNFKQMGVKAYVL
                     DGEERLKTIHDILNPNDKLVFSFEDLKYSGLTTKEYIVPPSFNFSKPTYFKTGEVFAE
                     VNFLQLLASDIKDEMLSEFLALEENMIVTFHIRAIDQMEAIKHVKRKITDLDKMKLEE
                     NKKAIRAGYDMDILPSDLVTYGAEAKNLLSELQNHDEKMFLITILFMNTSKSKGKLDN
                     TVFTLKSIANRHNCSLKNLNYRQEQGLVASLPLGINEVEIERGLTTSAAAIFIPFTTE
                     ELFIKGESLYYGLNALSRNIIMADRKKLKNPNGLILGTPGSGKSFAAKREITNAFLIT
                     DDDIIIADPEAEYSPLVEALKGQVIRISPISKDYVNPLDINIDYADEDNPLSLKSDFI
                     LSLFELVVGEKKLSAEEISVIDRCLPILYKTYFENPVPENMPILEDLYNLLQKQEEIV
                     GKKLAVEMEIYVKGSLNVFNHRTNVDTNNRVVCYDIKELGKQLKKIGMLVVQDQVWNR
                     VTINRASKKATRYYVDEFHLLLKEPQTANYSIEIWKRFRKWGGMPTGLTQNIKDLLAS
                     PEIENIFDNTDFILMLNQAGTDRDILAKKLNISKHQLSYVTNSGEGEGLIFYGNTIVP
                     FIDQFPKNTKLYSLITTKPEEVKKAGE"
     gene            2672..3697
                     /locus_tag="TV191_001791"
     CDS             2672..3697
                     /locus_tag="TV191_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEL1508270.1"
                     /translation="MSVSRSKEEFIKENTNKIICSDALETLRKIPDESISCCITSPPY
                     YRLRNYHKEGQIGRESTVEEYLDRLLQVFREVRRALKKEGTCFIVIGDSYADSGGGKG
                     QYIDPKYPKARNGSNALATENISGYKSKDLMGIPWRLALLLREDGWYLRSDIIWHKEN
                     AMPEACRDRPTRSYEHIFLLTKSPKYYYDYDAMVEPMKEVSKKRYVRGRKSDNKYLKE
                     NSGAKLQKINEARKYGEYKGDNVPQFRNKRDIWTINTTSFRGNHYATFPPKLVEICMI
                     AGCPKNEIVLDPFIGSGTVGFVALRHNRKYIGIELNEEYVNLAKNRISEEVKKFNEEQ
                     KQEVQKE"
BASE COUNT         1505 a          533 c          772 g         1034 t
ORIGIN      
        1 ttctacctgt tctttttgta acgctttatg aaaaggacaa tttacctttt gaaaaacatt
       61 tagcatatat cctcaggttt cataaaagta aaaagatcag gctatataaa gcgaggagca
      121 tttatcatac agagagagca aaaaagcaag atataggaaa taaaaataag gcaagcggaa
      181 ggaggaaaaa agttgaacaa agacaaaaga aaaaaacagg aacaacgaat taaaaaggat
      241 gagttggagc ttaggaaaaa tagaaaggag ctatccgaac ttaaaaaaac aggaaagaaa
      301 aaaacaaagt ctaaaacaaa agggaaatca tcgaagaaga atgggtggtt tccttttttt
      361 atgaaagagg agaaaaaaga aaccgtacag gataccattc catataagcg aatgttaaaa
      421 gacgggattt gtcaaattga aaagaataag tttaataaaa ccattcgatt tttggacatt
      481 aactatcgct taatggaaga aatagaccaa gagggaatat tttcggaatt ttcttctttt
      541 ctaaatttct ttgactcatc tgtggaagtg gagttcagct atatcaacag tatcggagaa
      601 aatgaagaaa tcaataaact gattgatatt aaggaaaata tagatgattt taatgaaatt
      661 agaaacgaat atagacaaat gctcttaaat caaagcagca aagggaataa tggattatca
      721 aagagtatgt acattacctt taccatagag gcggaggact taaagcaggc aaaaagtaga
      781 ttagagcgaa tggaaatgga tgtattaaac aactttaagc agatgggagt gaaagcctat
      841 gtgttagatg gagaggaaag acttaaaaca attcatgaca ttttaaatcc aaatgataaa
      901 cttgtttttt cctttgagga tttgaaatac agcggactga cgactaagga atacattgta
      961 cctccgtctt ttaacttttc caagccgacg tattttaaga caggagaagt ctttgcggaa
     1021 gtaaattttt tacagctttt agcatcagat attaaagatg agatgttatc agagtttttg
     1081 gcattggaag aaaatatgat tgttactttt catatcagag caatcgacca gatggaagct
     1141 attaaacatg taaaaagaaa aataacggat ttggataaga tgaagcttga ggaaaacaaa
     1201 aaagctattc gtgcgggata tgatatggat atcttgccaa gcgaccttgt aacttatggt
     1261 gcagaggcaa agaacttgct atcagaacta caaaaccatg atgaaaagat gtttctcata
     1321 acaattttat ttatgaacac gagtaaaagt aaggggaaac tcgataatac ggtatttacc
     1381 ttaaagtcca ttgcaaatag acataattgt agtttgaaaa acctaaatta tagacaagaa
     1441 caagggcttg ttgcaagcct tccacttggg ataaatgaag tggagataga acgaggactt
     1501 accacaagtg cagcagctat ttttatacca tttacaacag aagaactctt tatcaaggga
     1561 gaaagcctat attacggact aaatgcacta agcagaaata ttattatggc ggacaggaag
     1621 aaattaaaga acccaaatgg tctaatctta ggaacaccgg gttctggaaa gtcctttgca
     1681 gccaaaagag agattactaa tgcgtttttg attacagatg atgatattat cattgcagat
     1741 ccggaagcgg aatattctcc gcttgtagag gcactaaaag gacaagttat cagaatttct
     1801 ccgatttcaa aagactatgt caatccactg gacatcaata ttgactatgc ggatgaagat
     1861 aatcctttgt ctttaaaatc cgactttatt ttgtccctat ttgaattggt ggttggagaa
     1921 aagaaattaa gtgcagaaga aatttctgtt atagaccgtt gtttaccaat tttatataaa
     1981 acctactttg aaaatcctgt gccggaaaat atgccaattt tagaggattt atataatctt
     2041 cttcaaaaac aggaagaaat agtaggaaaa aagcttgcag tagaaatgga gatctatgta
     2101 aaaggaagtc ttaatgtatt taatcataga acgaatgtag atacaaataa cagagtggtt
     2161 tgctatgaca tcaaagaact gggaaaacag cttaaaaaga taggaatgtt agttgtgcag
     2221 gatcaagttt ggaatagagt tacaattaac agagcaagta aaaaagcaac cagatattat
     2281 gttgatgaat ttcatctttt gttgaaagaa ccgcaaacag ccaattattc gattgaaatc
     2341 tggaagcgtt tcagaaaatg gggtggtatg ccaacaggac ttactcaaaa tatcaaagac
     2401 cttcttgcaa gcccggagat tgaaaatatt tttgataata cggattttat tttaatgctt
     2461 aatcaagcag gaacagatag ggatatttta gccaagaagc tcaatatctc caagcatcag
     2521 ctttcttatg taacaaattc gggggaagga gaaggactta tcttttatgg aaatacgatt
     2581 gttcctttta tcgatcagtt tccaaaaaat acaaaactat attcactaat cacaaccaaa
     2641 cctgaagaag taaaaaaggc aggtgaatag gatgagtgtg agcagaagta aagaggaatt
     2701 catcaaagaa aatacaaata aaattatttg ttcggatgca cttgaaactt taagaaaaat
     2761 tccagacgaa agtataagct gctgcattac atctccccca tactacaggc tcagaaacta
     2821 tcataaagaa ggtcagatag gaagagaatc tacagtagaa gaatacttgg atagattgtt
     2881 acaggtattt cgtgaagtaa gaagagcttt aaaaaaagaa ggtacttgct ttatcgtaat
     2941 tggagattct tatgctgatt caggaggtgg aaagggacaa tacattgatc ctaaatatcc
     3001 aaaggcaaga aatggaagta acgctttagc tacagaaaat atctcagggt acaagtcaaa
     3061 agatttaatg ggaatacctt ggagattagc gttacttcta agagaggatg gttggtatct
     3121 gcgttctgat attatctggc ataaggaaaa tgctatgccg gaggcgtgta gagatagacc
     3181 tactcgttcc tatgaacata tttttttact tacgaaatca ccaaaatact attatgacta
     3241 tgatgctatg gtagagccga tgaaagaagt cagtaaaaaa agatatgtaa gaggaagaaa
     3301 atcggataat aaatatctga aagaaaattc cggagcaaag ttgcaaaaaa tcaatgaagc
     3361 aagaaaatat ggagaatata agggcgataa tgtcccgcag tttcgtaata aaagagatat
     3421 ttggactatc aataccacat cttttagagg caatcattat gcaacatttc caccgaaact
     3481 tgttgagatt tgtatgattg caggttgtcc taaaaatgaa attgtacttg atcctttcat
     3541 tggaagtgga acggtcggat ttgtggcact tcgtcataac agaaagtaca ttggaattga
     3601 attaaatgag gagtatgtaa atcttgcaaa gaatagaatc agtgaggagg tgaaaaaatt
     3661 taatgaagaa caaaaacaag aggtacaaaa agaatagaga aaaactctta aatcaagaaa
     3721 tacagtcttt acaatctcaa actcaagata attatgaaac aggatcctca aaaaatcaga
     3781 atgaaacctt gctgaaagac gaaacttacg ataagaaaca atttttatct gaaaagaagt
     3841 tatc
//
LOCUS       DARYXW010000118         3293 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.119, whole genome shotgun sequence.
ACCESSION   DARYXW010000118 DARYXW010000000
VERSION     DARYXW010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3293
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.119"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            587..1006
                     /locus_tag="TV191_001792"
     CDS             587..1006
                     /locus_tag="TV191_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622467.1"
                     /note="This protein contains a domain related to
                     Tuberculosis Necrotizing Toxin, which is the C-terminal
                     effector domain of outer membrane channel protein CpnT,
                     and which has a lethal NAD+-glycohydrolase activity;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycohydrolase toxin TNT-related protein"
                     /protein_id="HEL1508271.1"
                     /translation="MVDNLGNPITEQVTLKAGQIIDRYGSSSGRFTSPIENGVTLPFN
                     KRGLPYPEGYQDYYKYELVMDLTKKNIVNAYYQSEEIIRKQISVEMKKWNLSFDDLAN
                     IQKGEITKVFGQGGGIQIKFPTGVGIYKKMGLLKEIN"
     gene            1007..1330
                     /locus_tag="TV191_001793"
     CDS             1007..1330
                     /locus_tag="TV191_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009568641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508272.1"
                     /translation="MDNTNILNWKKDIEEAIKNRGFESLHYVLFDEEKRLPWAFHLYQ
                     KNGKFYVEGRDERSYIIGHSREYRKFDDAKHELLKKLELVIESNRLKKQLGEPTEYPS
                     PLWNE"
     gene            1589..2218
                     /locus_tag="TV191_001794"
     CDS             1589..2218
                     /locus_tag="TV191_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508273.1"
                     /translation="MTTLAGMSPEDSQRYIQWHKYAKAGLSPSDRVRILEISEKAPKI
                     EYLPGKTSDSILAISKGDRPNVEKVYSPDYIGFHRKQFDNGATRFQKFKPNVDYQDGL
                     VGDDLGNSFWLSTKDADIIQEIGKGNNRLYETLLGFDEGYLEDGPLYRLDVSPEVVSQ
                     KGVSIPSGNEKGANSWWRPGGRTYPGNIPEGVMQGISTKKGDHTWHAVN"
     gene            2200..2622
                     /locus_tag="TV191_001795"
     CDS             2200..2622
                     /locus_tag="TV191_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508274.1"
                     /translation="MARSQLEWEDVSQYEEVKGYGQRVWKHQGKYYFVAEEGGIAVQR
                     VVYELPYDLFELLESGERSLGDVHSKLQDGNWPPTEEEKKQSHRKFVIDTPTALIADP
                     TSVSLFSEEELSKLVPIAEQQWIDWKGKLPDDYVSPLK"
     gene            2881..3285
                     /locus_tag="TV191_001796"
     CDS             2881..3285
                     /locus_tag="TV191_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508275.1"
                     /translation="MSKNYTEADVAKLTELTTHNAKTKTALLGYYEANSVTSYEQIAH
                     QNKLTYFDAGSDGWNAMSRVDSKLAQRVNREFLIKQIEKRKTFILTSNPYTAQSIADV
                     SGIGKSYAKEIQILAENGYNIEKFERFWRAYK"
BASE COUNT         1133 a          525 c          771 g          864 t
ORIGIN      
        1 aagttcatta cgtgcttaca ttgttttatt taattacact aaaaaacttg agagagcaaa
       61 agaattatat gctagagcac tacatgactt gcctgattgt aagttagaat ttaatcagtt
      121 tgtagaatat tatttgatag gaaggaatta ataaaagaac tattgaaata ccatatggca
      181 ttttgagttc agatgcccag tcatggcagg aggcagcgaa caagatgctc agcgagctac
      241 attagtaggc aatatcctag gaggattcgc cgcctcaagc gtcgccagac ggttcagctt
      301 gaatgagcca atagcagcta gggtgacgaa accgacctac agccgccggc agcttttgaa
      361 gaaccttgag aacagcaggc tggcaagaga aagctcgagg tttgatgatt atcttcgaag
      421 agaataccgg ttaaagggaa ggtattttgc agaaagaacc actatttcaa atggaaagat
      481 aggttatctt tcatctgact attttgaagg caagcaaatt ccggttcgct ctagagcttt
      541 tgttgacgaa gcaggccata ttaaatggcc aaatgccgat ggctttatgg tggataattt
      601 aggtaatcct ataacggagc aggtcactct caaagcaggt caaatcattg atcgatatgg
      661 atcaagtagt ggtcgattta ccagtccgat agaaaatggg gtgacattac catttaataa
      721 acgtggatta ccctacccag aaggatatca agactattat aagtacgaat tagtaatgga
      781 tttgacgaag aaaaatattg ttaatgcgta ttatcaatct gaagagatta taagaaaaca
      841 aatatctgta gaaatgaaaa aatggaatct ttcctttgat gatttagcta atattcagaa
      901 gggtgagatt accaaagtat ttgggcaagg tggaggaatt cagattaaat ttccgacagg
      961 tgttggtatt tacaagaaaa tgggtttatt aaaggagatt aactagatgg ataatacaaa
     1021 tatattgaat tggaaaaaag atattgaaga agcaattaaa aatcgaggtt ttgagagttt
     1081 acattatgtt ttatttgatg aagaaaagcg acttccttgg gcatttcatc tttatcaaaa
     1141 aaatggaaaa ttctatgttg aaggaagaga tgagcgatca tatatcattg gtcatagcag
     1201 ggaatatcgt aaatttgatg atgccaagca tgaattgctt aaaaaattag aattagttat
     1261 agaatctaat cggttaaaaa agcagttagg tgaacctaca gaatatccct caccactatg
     1321 gaatgaatga gtttcatgta ttgtatgcca tggcaccaag cttttaggag gcagcgagca
     1381 agacgcccaa agagcaacat tagttgggaa tatcctagga ggacttgccg cctcaagcgc
     1441 cgctagaagg ttcagcttga atgagccaat agcaactagg gtgacgaaac cgacccacaa
     1501 ccgccagcag cttttgaaga accttgagaa cagcagactg gcaagagaaa gctcaaggtt
     1561 taagaattat gtagcaagag aaaaattcat gacaaccctt gcaggcatga gtcctgagga
     1621 tagtcagcgc tatattcaat ggcacaaata cgcaaaggct ggacttagtc cgtcagatcg
     1681 agtaaggatt ctagaaatat ctgagaaggc accgaagata gagtatcttc cgggaaaaac
     1741 atcagatagt atattggcaa tatccaaggg tgatcgtcca aatgtggaga aagtctacag
     1801 tccagattat attggatttc atagaaaaca atttgataac ggtgcaacta gatttcagaa
     1861 atttaagccc aatgtagatt accaagacgg tttagttggt gacgatttag gcaatagttt
     1921 ttggttaagt accaaggacg cggatattat ccaggagata ggaaagggaa ataaccgtct
     1981 ttatgagaca ctcttaggct ttgatgaagg gtatttagaa gatggtcccc tctatcgctt
     2041 agatgtttca ccagaagttg tttcacaaaa aggtgtttca ataccaagtg gtaatgaaaa
     2101 aggggcaaat agctggtggc gtcctggagg tcgtacttat ccggggaata taccagaggg
     2161 agttatgcaa ggtatcagta caaagaaagg agatcacaca tggcacgcag tcaattagag
     2221 tgggaagatg ttagtcaata tgaggaggta aagggctatg gtcaaagggt gtggaagcat
     2281 caagggaaat attactttgt tgccgaagaa ggtggcattg ctgttcaacg agtagtatat
     2341 gagttaccgt atgacttatt tgaattgttg gaaagtggag aacgtagtct tggagatgtt
     2401 cattcaaagc tacaagatgg taattggcca ccaacagaag aggaaaagaa gcaaagtcat
     2461 agaaaatttg ttattgacac accaactgcg ctgattgcag accctactag tgtgtctctg
     2521 ttctcagaag aagaattatc aaaattagtg ccaatcgctg aacaacagtg gatagattgg
     2581 aagggaaagc tgccagatga ttatgtcagt cctttgaaat aatgtttaag atagcggagc
     2641 cgagattagc tctgctattt taaagcatgt tcttaataat tagcctgcga cagcttatca
     2701 gggagtagct cgtcaccttg aagccaatgc caagcgtctc caagcgccgc cagaaggttc
     2761 agcttgaatg agccgatagc agctaaagtg acgaaatcag cgaaaataac cctttctgaa
     2821 aaggtactag acacaaaggt tcggtttgat gagtctcgca ttgtggctta cgcagaaagt
     2881 atgagtaaga actatacaga agctgacgtg gccaaattaa ccgagctgac cacccacaat
     2941 gcaaaaacca aaacagcttt gctgggatat tacgaagcaa acagcgttac ttcgtatgaa
     3001 caaattgcac atcaaaataa gttaacttac tttgatgccg gaagtgatgg ttggaatgcg
     3061 atgtcgagag tggattctaa gctagctcaa agggttaatc gtgaattttt gataaaacaa
     3121 attgagaaaa gaaaaacatt tatattaacg tctaatccat atactgctca atcaatcgca
     3181 gatgttagtg gtatcgggaa gtcttatgct aaagaaattc agattttagc agaaaatgga
     3241 tataatattg aaaaatttga aaggttttgg agggcatata aatgagtgaa gaa
//
LOCUS       DARYXW010000119         3256 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.120, whole genome shotgun sequence.
ACCESSION   DARYXW010000119 DARYXW010000000
VERSION     DARYXW010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3256)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3256)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3256
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.120"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(<1..1556)
                     /locus_tag="TV191_001797"
     CDS             complement(<1..1556)
                     /locus_tag="TV191_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1508276.1"
                     /translation="MFYLKLAWNNLRKSLSVTAPFLLASTVLYMLNCIVLIIMMSPVS
                     ESMRHGFMLLGLAIFVLIIFATIMEIYSYNFLLKQRSREFGLYNILGMNKKQVGLVST
                     IELVFMYLGTVVVGSILSAIFSHVFYLIFANLVGAVHLELQINPVAFIYTTLIFAAIF
                     GLLEVVGLIKIRKTSPLMLFRHKEQGEKEPKGNLLLAALSIILLSIGYYISLSSTKLT
                     ALDTLYRFFIAVIIVIIGTYLFYISFMTWHLKRRRQNKAYFYQPEHFVSTSQMIFRMK
                     QNAVGLANITLLAVMAFVAIATTTALYANSEAMSNQLFPKNTHINFDNSEIDNQKEVF
                     NRLIVEKTNKPASDFLVYYSSMVSFEVSQKETIVVTKESLLNPSPVTTGYVYLVTQDD
                     FRALGNQLPELKDNQTAFFKQRGDSQLRQLDILGKSYTNVKNLTSVTFPEAANTYNGA
                     VLVVKDMETLKDIQDSIQSINHTGGRASISAYADLTKADLRSISDDKGIISDGDTVIG
                     HIETKKEYLRS"
     gene            complement(1559..2311)
                     /locus_tag="TV191_001798"
     CDS             complement(1559..2311)
                     /locus_tag="TV191_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1508277.1"
                     /translation="MLLEINHLEKVFRTRFSKEETRALQDVDFKVDKGEFIAIMGESG
                     SGKTTLLNILATLEKPTKGSVLLNGTDITKIKEGDLANFRLQNLGFVFQDFNLLDTLS
                     IRDNIFLPLVLNRKPFKEMERRLNIIAPKLRIETLLDKRPFEISGGQKQRVAIARSLI
                     TNPQLLLADEPTAALDYRNSEDILNLFEAINLDGQTLLMVTHSANAASHAKRVLFIKD
                     GRIFHQIYRGNKTNLEFSKDISIAMAGLLGGE"
     gene            2642..3121
                     /locus_tag="TV191_001799"
     CDS             2642..3121
                     /locus_tag="TV191_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing protein"
                     /protein_id="HEL1508278.1"
                     /translation="MAKKIKKTLGTVGKLFSIIPDTTEIIGKTIDNTRPIIEKHMEQK
                     HEKEMQLTLLDDVINLPVDKAQKHLEQLGFVVALLPVKPSKKWIHASLNEVVSMSPKP
                     GKHKLGSLVKLYYVTVDVLEKSQAILDQETLKAVERNQKIADTIEAVKQIKLPFKKR"
BASE COUNT         1036 a          605 c          610 g         1005 t
ORIGIN      
        1 gatcggaggt attccttttt agtttcgata tgacctataa cagtatcacc atcactaatg
       61 attcccttat catcactaat actcctaaga tcagccttag ttaaatcagc ataggccgaa
      121 atgctggccc ttccgccagt atgattaatg ctttgaatgc tatcttgaat gtcctttagt
      181 gtttccatat ctttgaccac aagaactgca ccattataag tgttagctgc ctctgggaag
      241 gttactgatg ttaaattttt gacattggta tatgatttgc ccaaaatatc cagctgtcgt
      301 aattgactat cccctctttg cttaaagaag gcagtctgat tgtcctttaa ttcaggcaat
      361 tgattgccca aggcgcggaa atcatcttga gtgactaagt agacatagcc tgtagtgact
      421 ggactaggat ttagcaagga ttctttggtt actacaatgg tttctttttg ggatacttca
      481 aaagaaacca tgctactata atagactaga aaatccgagg caggcttatt ggtcttttca
      541 acaataagtc tgttaaaaac ctctttttga ttgtcaatct ctgaattatc aaaattaata
      601 tgagtatttt taggaaaaag ctggttagac attgcctcgc tattagcata aagcgcagtt
      661 gttgttgcta ttgcaacaaa ggccataaca gctaagaggg taatatttgc caagcctaca
      721 gcattttgct tcattctaaa aatcatctga gaggtgctga caaaatgctc tggctggtaa
      781 aaataagcct tgttttgacg acgacgcttt aagtgccaag tcataaagga aatgtaaaag
      841 agataggtcc cgataataac gataataact gctataaaaa accgatataa agtgtctaat
      901 gctgtcagct ttgtcgatga taaggagatg taatagccaa tactaagcaa tatgatggat
      961 aaggctgcta gtaataaatt accctttggc tctttttcac cctgttcttt atgacgaaag
     1021 agcattaagg gagaggtctt tctgatttta atcaagccaa caacctctaa taaaccaaag
     1081 atagcagcaa agattaaagt ggtgtaaata aaagcaacgg gattgatttg taattctaaa
     1141 tggactgctc cgaccagatt agcgaaaatc aaataaaaga cgtgtgaaaa aatagctgat
     1201 aggatacttc ctacgactac tgtccctaag tacataaaaa caagctcgat cgttgagact
     1261 aaaccaacct gctttttatt cattcccaaa atattgtaca gaccaaattc tcgacttctt
     1321 tgctttagta aaaaattata gctataaatc tccataatag tggcaaagat gattaaaaca
     1381 aagattgcta gtcctaatag cataaaccca tgtctcatcg attctgatac ggggctcatc
     1441 atgataatca agacaataca attgagcata tataaaacag tgcttgccag taaaaaagga
     1501 gctgtgacgg ataaggactt tcgtagatta ttccaagcta gtttgagata aaacatcttt
     1561 attcacctcc taaaagaccg gccatggcaa tcgagatgtc tttgctaaat tctaaattcg
     1621 ttttatttcc acgatagatt tggtggaaaa tacggccgtc cttgataaac agtactcgct
     1681 tagcatggct agcagcattg gcagagtgtg ttaccatcaa gagtgtctga ccgtctaggt
     1741 taatggcctc aaaaagattg agaatatcct ctgaattgcg gtaatcaagt gctgctgttg
     1801 gttcgtcagc taataataat tgcggattgg tgattaagct tcttgcaata gcaacccttt
     1861 gcttttgacc accagaaatt tcaaatggac gtttatctaa aagcgtttca atgcgcagct
     1921 taggggcaat gatgttgagc cgtctttcca tttctttaaa tggcttacgg tttaaaacaa
     1981 ggggtaaaaa gatattatct ctgatcgata gggtgtctag gaggttaaaa tcctgaaaaa
     2041 caaagcctag gttttgaagt cggaaattag ctaggtcacc ctccttaatt tttgtaatgt
     2101 cagtgccatt caataaaaca gatcccttgg ttggtttttc cagagttgcc agaatattta
     2161 atagggttgt tttccctgag cctgactctc ccatgatggc aataaactca cccttgtcaa
     2221 ccttaaaatc aacatcttgt aaggctctag tttcttcctt tgaaaagcgt gtccgaaaaa
     2281 ccttctctaa atgattaatt tctaataaca tatgaaactc ctttgtgtct attatactct
     2341 tttagcttta aatatagcca ctatcgtgac gtatttagct agtgatgcat ttagtgcctt
     2401 ttgtcagcct taaccactcc ttctttcatg aagcagccca gctctcaaca agaatcgtct
     2461 tagctgactg aacctattgc tctaaactct tttttcttta cagcttatag tttaccctaa
     2521 ttaatagtct ggttagctta caagatttga tgggtgactt acagatttgt aagttttata
     2581 acatcatttt tcttatcatt ttgatataat gaaaggagaa ttctatttag gagaagcgtc
     2641 aatggctaag aaaatcaaaa aaacgctagg gactgtcgga aagctgtttt ccattatccc
     2701 tgataccact gaaattatag gaaaaacgat agataacacc cgtcccatta tcgaaaagca
     2761 tatggaacaa aagcatgaaa aggaaatgca gctaacgctt ttagatgatg tgattaattt
     2821 acctgttgat aaagcgcaaa agcatctgga acagctaggt tttgttgtcg cactattgcc
     2881 ggtcaagcct agtaaaaaat ggatacatgc tagcttaaat gaggttgttt ccatgtcacc
     2941 taagcctgga aagcataagc tgggaagctt agtaaagctt tattatgtta ctgtagatgt
     3001 ccttgagaaa agtcaggcta ttttagatca agagacccta aaggctgtcg aacgaaatca
     3061 aaaaatcgct gataccatcg aagctgttaa gcaaatcaag cttcctttta aaaagagata
     3121 aggctatact gtaaaaaata agctgatacc gttaggatca gtttattttt tatgttgtga
     3181 ctttaagtct atctcgctta gcaggtgcca aacaaataaa ccacccgtta tgtaccgacc
     3241 ttcaatggtt aaagtt
//
LOCUS       DARYXW010000120         3221 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.121, whole genome shotgun sequence.
ACCESSION   DARYXW010000120 DARYXW010000000
VERSION     DARYXW010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3221)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3221)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3221
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.121"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(360..1334)
                     /locus_tag="TV191_001800"
     CDS             complement(360..1334)
                     /locus_tag="TV191_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEL1508279.1"
                     /translation="MKLALVGTGMIVKEVLPVLKEIKSIDLMAIVSTPRSLETAEALA
                     DAFGIQQASCQLAEVLKNEEVDTVYVATPNHLHFEVAKQALEAGKHVICEKPFTMTAK
                     ELDALSSIARAKQLILLEAITNQYLPNTQFIKDHLTELGEIKLVECNYSQYSSRYDAF
                     KRGEIAPAFDPKKGGGALRDLNIYNIHLLVGLFGKPQTVQYLANMERQVDTSGVLLMD
                     YERFKAVCIGAKDCSAEIVSTIQGNKGFLSVLGAPNAVPELLLAIRGEQARTVNFNHP
                     SHRMYDEFIAFSDIISNKDMERAEQALEHSKAVMAVLEQAAASLESDS"
     gene            complement(1335..1793)
                     /locus_tag="TV191_001801"
                     /pseudo
     CDS             complement(1335..1793)
                     /locus_tag="TV191_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623303.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
     gene            complement(1993..2691)
                     /locus_tag="TV191_001802"
     CDS             complement(1993..2691)
                     /locus_tag="TV191_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEL1508280.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLRNGFTVYGVDKAKKPDLSGDF
                     QFLQLDITGDLAELFEAVPRVDVLCHTAGVLDAYKPLLDTTQADFEALFQVNFFAAVR
                     ITRHYLAQMLTAQSGIIINMCSIASFMAGGGGAAYTSSKHALAGFTRQLALDYAKAGI
                     QVFGIAPGAVQTAMTATDFEPGGLAQWVADETPIGRWLRAEEIAELTMFLASGKASAM
                     QGEIVKIDGGWSLK"
     gene            complement(2684..2920)
                     /locus_tag="TV191_001803"
     CDS             complement(2684..2920)
                     /locus_tag="TV191_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEL1508281.1"
                     /translation="MTFEEILPGLKAKKKYVRKGWGGAENYVQLFDSIEQNGVALEVT
                     PYFLINVSGAGEGFSMWAPTPCDVLATDWVEVYD"
BASE COUNT          936 a          818 c          610 g          857 t
ORIGIN      
        1 gcataatgac ttcctccgtt tgtacataga tcatctcatt atagcacaaa tggccttaat
       61 ttgcagaaaa aacaagaatg ctgcaatagt ccttagcttc agacaaactc ccttacctac
      121 cttgactcct tttttaaagc agctagctag agctgcctgt catcgctaag tatcaaagat
      181 gtcgtaaaca aagcaagctg caaattagac ccctcactat gaaaaaagca gttaggctcc
      241 gcgattgaaa gactccgagt catcaggaac aagacctgta tctgatagaa caagaagggt
      301 catcacttct taagacagct agcaaaaaag atgacttagc ttgtagccac tagctactct
      361 tagctatcgc tttctagcga agctgctgcc tgctctaaaa cagccatgac tgccttgctg
      421 tgctccaagg cctgctctgc cctttccatg tccttattag agataatatc tgaaaaggca
      481 ataaattcat cgtacatgcg atgagacggg tggttaaagt tgacggtcct tgcttgctca
      541 cctcgaatgg ctagtaaaag ctctggtaca gcattaggag cacctaaaac agaaagaaag
      601 cctttattcc cctgaatcgt agagacaatc tctgcactgc aatccttagc cccaatacaa
      661 acagccttaa atcgctcata atccatcagc aaaacaccag aggtgtcaac ctgccgctcc
      721 atattagcta ggtactgaac cgtttggggc ttgccaaata agccaacgag cagatggata
      781 ttataaatat tcaaatcacg caaggcccct ccaccctttt taggatcaaa ggctggtgca
      841 atctccccac gcttaaaggc atcataacga gaggaatatt gagaataatt gcactccaca
      901 agcttaatct ctcctaactc agtcaagtga tccttaataa attgggtgtt tggcaaatat
      961 tggttggtaa tagcttctaa taatatcagc tgcttagctc ttgcaatgct gcttaaagca
     1021 tcaagctcct tggctgtcat ggtaaatggc ttttcacaaa tgacatgctt accagcctca
     1081 agggcttgct tagccacttc aaaatgcaaa tgatttgggg tggcaacata aaccgtatcc
     1141 acctcttcat tttttaggac ctcggctagc tgacagctgg cctgttgaat gccaaaggcg
     1201 tcagcaagcg cctctgcggt ttcaagacta cgaggcgttg aaacaatcgc cattaagtct
     1261 atgcttttga tctcctttaa aacaggcaaa acctctttga caatcatgcc tgtaccaaca
     1321 agggctaatt tcatttattt ctccttttta gcagcttcag ggtaaaccct ctgaaactcc
     1381 tctaacacaa taaggctatc ctcggtaaag cgtaagccta cctcttcaaa ataaggtctg
     1441 aaaaaggcct catgaagcag ccgccattct tccaagcttt tatcaccctc tccttcctta
     1501 taggcatgct ctgctggcac gtccttgaag ggaacaagac taaccttagt aatctggata
     1561 atacagatcg cctgatccct actatccaaa atcacgtcat agctgccctc tttggaaagc
     1621 ggctcatgat caggctcata tcagtcatag gcagaggctg tagctgtttt agtgccttct
     1681 agcactaatt gcgctaataa atcaggctca gctccaaagg cccaggcctc agctagatca
     1741 ccaacaccag gattgatttg ctggtattga gaccataatt cttctgcagt catgttatca
     1801 cctctattga tcgaatcctc tagacaggta ggctcctgct gtattaagca aacctactag
     1861 gcactaggct tcatggaaaa aacttcatca gctccctctt agcctgtgac aagattgctt
     1921 gatacagcta tcaactgtca ccctctgtac agacaagcca gatcttgcta ggccttatgt
     1981 cgatgtgctg tttcacttta agctccaacc gccatcaatt ttaacaattt ctccctgcat
     2041 ggcgctagct tttccagatg ccaaaaacat ggtcagctcg gctatttctt cagccctaag
     2101 ccaacgaccg ataggagtct catcagccac ccactgggct aagccacctg gctcaaagtc
     2161 tgtggctgtc attgctgttt gcactgcgcc aggggcaatg ccaaaaacct gaatgcctgc
     2221 cttggcataa tcaagcgcta gctgtctggt aaaaccagcc agagcatgct tgctggaggt
     2281 ataggcagct ccgccgccac ctgccatgaa gctagcaata gagcacatat tgatgataat
     2341 acctgattga gctgtcagca tctgtgccaa atagtgacgc gtgatgcgga cagctgcaaa
     2401 gaaattgacc tgaaagagag cctcaaaatc agcctgtgtg gtatcaagca agggcttata
     2461 ggcatcaaga acgcccgcag tatgacacaa cacatcaacc ctaggcacag cctcaaaaag
     2521 ctcagctaaa tcacctgtaa tatctaactg taaaaactga aaatctcctg ataaatcagg
     2581 cttttttgcc ttgtcaaccc cataaacagt aaagccattt ctcaaaaaca ggcgcgcctg
     2641 tgccagtcct atgcccgatg acacaccagt gatcagcacc cgcttagtca tagacctcta
     2701 cccagtcagt agcaagaacg tcgcagggag tcggtgccca catggaaaag ccctcgccag
     2761 ctcctgacac gttaatcaaa aagtaaggcg tcacctcaag tgccacacca ttttgttcaa
     2821 tgctatcaaa cagctgaaca tagttttcag cgcctcccca gcccttacga acgtattttt
     2881 tcttggcctt caagcctggc aaaatctctt caaatgtcat ggttttctcc ttttataggt
     2941 ctacatcata gcatgagctc ttttaatgat cattatacca atttactcag cttttgtaag
     3001 cttaaagatc acgaaagtcg caaacgtaca agtttgcttt gtttttagat aaggattcat
     3061 catcttaact aattatgaca taatctaagt gatatgaaat cctttgtaac ccacaccagc
     3121 tttttataat acactaacct gagtgtcttt aaaactgcgg ctgtaattct tgattaagct
     3181 aatacagcat gtctagccag tatatgaaaa taattggaat t
//
LOCUS       DARYXW010000121         3171 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.122, whole genome shotgun sequence.
ACCESSION   DARYXW010000121 DARYXW010000000
VERSION     DARYXW010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3171)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3171)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3171
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.122"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(809..1825)
                     /gene="adhP"
                     /locus_tag="TV191_001804"
     CDS             complement(809..1825)
                     /gene="adhP"
                     /locus_tag="TV191_001804"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEL1508282.1"
                     /translation="MKAVVVNQTSSGVEVVEHDVPSIGHGEALVKVEYCGVCHTDLHV
                     AHGDFGQVPGRILGHEGIGIVEKLGEGVTSLKVGDRVSIAWFFEGCGHCEYCTTGRET
                     LCRSVKNAGYSVDGGMSEYAVVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAGA
                     APGQWIVIFGAGGLGNLAVQYAKKVFNAHVVAVDINNDKLELAKEVGADIVVNGKEIE
                     DVAGYIQEKTGGAHGVVVTAVSKVAFNQAIDSVRAGGTVVAVGLPSEYMELSIVKTVL
                     DGIKVVGSLVGTRKDLEEAFAFGAEGLVVPVVEKVPVETAPEVFDEMERGLIQGRKVL
                     DFTL"
     gene            complement(2028..3080)
                     /locus_tag="TV191_001805"
     CDS             complement(2028..3080)
                     /locus_tag="TV191_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEL1508283.1"
                     /translation="MKAATYVAPGQLELIDQPKPEILAPTDAVVRLLKTTICGTDLHI
                     LGGDVPETTHGTILGHEGIGIVESVGSAVNNFKVGDKVIISCITACNTCYYCKKGIPA
                     HCESGGWILGHLINGTQAEYVHIPQADGSLYHAPKTVEDDALVMLSDIFPTSYEIGVQ
                     SAKVKPGDTVCIVGAGPIGLAALLTAQFYSPAKLIMVDLSESRLEAAKRFGATDTICS
                     GDLDDIVKKVHELTDGRGVDVAIECVGYPATFDICQKIIAIGGHVSNVGVHGKPVSLD
                     LQDLWIKNITMSTGLVNANTTEMLLNVLKSGKIDATKMVTHHFKLSEVEKAYEVFKNA
                     GSNNALKVIIENDITA"
BASE COUNT          954 a          722 c          511 g          984 t
ORIGIN      
        1 aatagaaaat aaggtcatta aaaatgcact gattacacta aaaaaagcta ctattacata
       61 taacaatcta tgacttctta caatttcttt cataaatcca cctaaaagat tttataaata
      121 aattataatg tacaagtatc gtatcctaaa aaacttccct tattcgggac acaacatttt
      181 tcatctatat tttaaatcat actaccttgt tactaaaaac gtagataata atttagctta
      241 taacccatgt ttttagcaat atgttatgtc attattcttt tttcctacag tgcttcctaa
      301 aatttgtgaa gacgaattgt caaattaagt gcaacgcttt tccataaaag agtttataag
      361 gtagtttcca gttaggacat cttctagaac gatcatttca tttatcttcc cactcttata
      421 tgatagagct ctcaatatca gtcaagtcag ttcctttagg aaactactct ttgattaacc
      481 cattggtatt ttcatttgtc ctacgttatc aaggggtgtg aggagcagag aaataaactt
      541 ctagattgag ttcctgtgtt aatctctaat attgttcaaa cccagtatct ctatcagagg
      601 ttacaatatg tccaactttc tctggtactg tctttcaagg ggcaatcatg gtattaataa
      661 ctagctggct cttttacatc tttagatacc aagctttttt taccagttag tttcaccaaa
      721 aaagccctta gaaaattaat tctaaggact ttattcatca tttgggacaa tcagcttgtc
      781 tggctgctga ctttttctga aatcagcctt aaagcgtgaa atccaatacc tttcttcctt
      841 gaatgagacc acgttccatt tcgtcaaaga cttctggagc agtctcaact ggaacctttt
      901 ctacaactgg cacaaccaga ccttctgcac caaaggcaaa ggcttcttcc aagtctttac
      961 gagttcccac aagtgatccg actaccttga ttccgtctag gacagtcttt acgatagata
     1021 attccatgta ttctgatgga agtcctacag caacaacagt tcctcctgca cgcacactat
     1081 caatagcttg gttaaaggct actttagaaa cagcggttac cacaacgcca tgagcaccac
     1141 ctgttttttc ttggatatag ccggcaacat cttcgatttc tttaccattg acaacgatat
     1201 ctgctccaac ctccttggcc agctctagct tatcattgtt aatgtccact gctacgacat
     1261 gagcattgaa aaccttttta gcatactgaa cagctaggtt accaagtcca ccggcaccaa
     1321 agataacaat ccattgtcct ggagcggcac ctgcttcttt gatagcctta taggttgtaa
     1381 cgcctgcaca ggtaattgat gatgcttgag ctgggtcaag accatctggc actttcacag
     1441 catagtcagc tgtaacaact gcatactcac tcatcccacc atcaactgaa tagccagcat
     1501 ttttgactga acggcataga gtctcgcgac ctgttgtaca atattcacaa tgaccgcagc
     1561 cttcaaagaa ccaagcaatt gatacacgat caccaacctt taaggaggta acgccttcac
     1621 ctagcttttc gacaataccg ataccttcat gaccgaggat acgccctgga acctgaccaa
     1681 aatcaccatg cgcaacatgc aagtcagtat gacatacgcc acaatattct actttaacaa
     1741 gagcttctcc atgaccgatt gatggtacat catgctctac aacctctaca ccactgctgg
     1801 tttggttaac aactacagcc ttcataggat gcctccaatt tctaagtctc ggtttatcta
     1861 tttttgcaac cgtttacaat ttgtattgta tactttttca caaggtttgt caaccaattt
     1921 cttgaaagtt ttctgaaaat aaacttaacc agttaagttg gctaaaaaac agcatctaga
     1981 ccattccaaa tgctgttgtc acttttatct atttatacct tattccttta ggctgtaatg
     2041 tcattttcaa taatcacttt aagggcgtta ttactgccgg catttttaaa gacctcatag
     2101 gctttttcaa cctctgacag cttaaagtga tgtgttacca tcttagttgc atcaatctta
     2161 ccagatttca acacattcaa tagcatttct gttgtattag cgtttactag gccagttgac
     2221 attgtaatgt ttttgatcca taggtcctgt aggtccaaac taactggttt tccatggaca
     2281 ccaacgttag aaacatgccc gccaatagca ataatctttt ggcaaatatc aaaggtagca
     2341 ggatagccta cacactcaat ggcaacatca acacctcgac catcagttaa ttcatggact
     2401 tttttgacaa tatcatcaag gtcaccagag caaatcgtat ctgttgctcc aaagcgctta
     2461 gctgcttcta aacgtgattc tgacaagtca accatgatca gcttagctgg tgaataaaat
     2521 tgtgctgtta aaagagctgc tagtccgata ggacctgctc caacgataca cactgtatca
     2581 cccggcttta cctttgcaga ctgaacgcct atttcatagg aagttgggaa aatgtctgac
     2641 agcataacca aggcatcatc ctcaacggtt ttaggagcat gataaagact gccatctgct
     2701 tgaggaatat gaacatactc tgcttgtgtc ccattaatca aatgccctag aatccagcca
     2761 ccgctttcac aatgagcagg aattcctttt ttacaataat agcaggtatt acaggctgtg
     2821 atacaggaaa taataacctt atcacctacc ttaaagttgt tcactgcaga gccgactgac
     2881 tcgacaatac caataccttc atgacctaaa atggtaccat gagtagtctc tgggacatct
     2941 ccacctaaaa tatgtaagtc tgttccacag attgttgttt tcaataaacg aaccacagca
     3001 tctgtcggag caagaatctc tggttttggt tgatcaataa gctccagctg acctggagca
     3061 acatatgtag ctgctttcat aaaacgtctc caaatttagt ctagaaaatg taatcgatta
     3121 catttttagt ataatttttt acaccctctt tgtcaattaa taaagggtaa t
//
LOCUS       DARYXW010000122         3153 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.123, whole genome shotgun sequence.
ACCESSION   DARYXW010000122 DARYXW010000000
VERSION     DARYXW010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3153)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3153)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3153
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.123"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            178..933
                     /locus_tag="TV191_001806"
     CDS             178..933
                     /locus_tag="TV191_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002962809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEL1508284.1"
                     /translation="MSQKEVGHQFLARLGKKRLRPGGVEATNWLVQQGEFSSDCKVLE
                     VACNRCTTSIELAQTYQCHITAVDLDTKVLAEARKAIEAAQMQDYIHLTQANALKLPF
                     ADNSFDIVINEAMLTMLNDAAKEKALKEYWRVLKPGGRLLTHDVSYEADETKAIIEQL
                     RDTINVNVSPLQLDAWRQLLVKSGFTAVNYSYGNMTLMSPLGMIKDEGVVAAIRIMLR
                     GMKKENRKQFLKMRHFFNKTGRKLCYIAAVSQK"
     gene            961..1299
                     /locus_tag="TV191_001807"
     CDS             961..1299
                     /locus_tag="TV191_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEL1508285.1"
                     /translation="MSLIRKIPTSTVIDLKAEVPIEEDQILSRTLVQRKDLGITLFSL
                     DKGQEIGRHSSPGDAMVNVLSGVVDITIGEACYEVAAGETIIMPANIPHSLFAKEAFQ
                     MLLVVVKPEA"
     gene            1301..1606
                     /locus_tag="TV191_001808"
     CDS             1301..1606
                     /locus_tag="TV191_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEL1508286.1"
                     /translation="MLADLLELVRYHDDQIASRSLHQSLGFKQSVVLYAMYQGETISN
                     ESSPEGKLLLVLEGRLLVSLTDQAHDMKAGGLISISAHQFYHLEAATNCKYLQIEMV"
     gene            2357..3094
                     /locus_tag="TV191_001809"
     CDS             2357..3094
                     /locus_tag="TV191_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1508287.1"
                     /translation="MNIFILEDDLGQQFRLEMKIQEILDKHHWTCDRFEVYGKPYQLL
                     ANVTERGRHQLFFLDIQIRNDEKKGLAVAREIRKRDPYALIVFVTTHSELMPVSFRYQ
                     VSALDFIDKELSMKHFSDRIERAIIYAYEEQENVTSEGLFIFATAKAQVQVPFSSLLF
                     IETSSTPHKLILHSQNERIEFYGFLSEVLKQDSRLVQCHRSYVINPYNVSFLDRDKRL
                     LYFKNGQSCMVSRLKMKALEASIKALH"
BASE COUNT          956 a          536 c          695 g          966 t
ORIGIN      
        1 aagaaatatg agccaattct atgatttatc ataaaaacaa tcatcagaaa tgcttaagct
       61 tcattgagga tatgctttaa gtgtgatata gttgtagtaa tcatttattg atcaatttgt
      121 taacagttag tttattctaa gtgatgatat atagcagagc aaataggagg gcatgtgatg
      181 tctcaaaaag aagttggtca ccagttttta gctcgactgg gaaagaaacg actacggcct
      241 ggcggtgttg aggcgacgaa ttggctggtt cagcaaggag agttttcgag tgattgcaag
      301 gtcttggaag tggcctgcaa ccgttgcacg acctccattg agctggcgca gacttatcag
      361 tgtcatatta cagcagtaga tttggatacc aaggtactgg cggaggcaag aaaggctatt
      421 gaggcagcac aaatgcaaga ctatattcac cttacccaag ctaatgcctt gaagctgcct
      481 tttgcagata atagctttga tatcgttatt aacgaagcta tgctaaccat gttgaatgat
      541 gctgcaaagg aaaaagcact taaggaatat tggcgtgttt taaagccggg tggtcgccta
      601 ctaacgcatg atgtttccta tgaagctgat gaaacaaagg ctattataga gcaactaaga
      661 gatacgatta atgtgaacgt atcgccattg cagttagatg cctggagaca attgctggta
      721 aagagtggct tcacagcagt caattactcc tatggtaata tgacgctcat gtccccgctt
      781 ggcatgatta aagatgaagg ggttgtcgct gcgattcgta ttatgctgcg cggcatgaaa
      841 aaagaaaatc gaaagcagtt tttaaagatg cgtcatttct tcaacaaaac tggaagaaag
      901 ctgtgttata ttgccgctgt aagtcaaaaa taactagaat aatggtaaag gagaagtgac
      961 atgtcattga ttcgtaaaat tccaacaagc acagtcattg atttaaaggc agaagtgcca
     1021 attgaagagg atcaaatatt aagtcgaaca ctagttcaaa gaaaagattt gggcataacc
     1081 ctgttttcat tagataaagg acaagaaatc ggtcgtcatt catcaccggg agatgcaatg
     1141 gttaacgtgt taagtggagt agttgacatt actattggag aagcctgtta tgaggtagct
     1201 gctggcgaga cgatcatcat gcctgctaat attcctcata gcttatttgc taaggaagcc
     1261 ttccagatgc ttttagttgt tgtaaagccg gaggcttagc atgttggctg atttattaga
     1321 attagtaagg tatcatgatg accaaatagc tagtcgttcg cttcatcaaa gcctaggctt
     1381 taagcaatct gttgttttat atgccatgta tcagggagag acgattagta acgaatcaag
     1441 ccctgaaggt aagctcctgc ttgtcttaga aggaaggttg ctggttagtc ttacggatca
     1501 ggctcatgac atgaaagcag gcggattgat cagtatctct gctcatcagt tttatcattt
     1561 agaggctgca acaaattgta aatacctgca aattgaaatg gtctaaaagt atagagtgac
     1621 tctcttgaat cttgccccct aggctggtgt tttagctgcc ttagggggct ttttgtgttt
     1681 agtgtcataa ggtttagctg aagatctagc ttacttcaaa tcactcaaag tgattaataa
     1741 taataacaat tacctgtttt gatgataaaa agattgtttt tatgataaaa taaatgacag
     1801 aatatcccgg atacctaatg tatttgttac caataattct agaaacttat tgcttggaga
     1861 aggtatagct acaagcagct aatcatcaga tagcctcagt aacctgacta gccattgtta
     1921 gttttcctta tttaccattt aagacataat cagtaccatt taagatttta actccctgct
     1981 ccctagcttt gtgttagaat gtctgtgcaa ggagatcagt gtgtggattg atagctgatg
     2041 acttgtcaaa caaaagtgat agtcgttaag agctctctct caaagaggta tgacttgcgg
     2101 ctcgtgctag tatattatct gtggtaaaaa aattgtttga ggcgcgtgat tcgctaaggc
     2161 ctattgaaaa cgctgcaatg acaagttggt tagaagtcat tgacaacctt tagttaataa
     2221 gcttaacggt catggtttta atggtgatgc taaaaagata ctgttcatga aggagagcgt
     2281 tctagctatc acttgttcaa aaagctgctt tagtctccta aaaaaacgat aagctaaagc
     2341 aataaggagg ttctaaatga atatttttat tctcgaagat gatctaggcc aacagtttag
     2401 gcttgagatg aagattcaag agatattgga taagcatcac tggacttgtg atcgttttga
     2461 agtttatgga aagccctacc agcttctggc aaatgttaca gagagaggca ggcatcagct
     2521 tttctttctc gatattcaaa ttcgaaatga tgagaaaaag ggcttagctg ttgctcgtga
     2581 gatcagaaag cgtgaccctt atgccctcat tgtttttgtc accacacatt ctgagcttat
     2641 gccagtttct tttcgttatc aggtgtctgc tctagatttt atcgataagg aattgtcaat
     2701 gaaacatttc tcagatagga ttgaaagagc cattatatat gcttatgaag agcaagaaaa
     2761 tgtaacctca gagggcttat ttatttttgc aacggctaag gctcaggtgc aggttccttt
     2821 ttcaagccta ttgttcattg agacctctag tactcctcac aagttgattt tgcattctca
     2881 aaacgagcga atagaatttt atggctttct ttcagaggtt cttaagcaag attccagact
     2941 agtccaatgt catcgttctt atgttatcaa tccttacaat gtttcgtttc ttgatcgtga
     3001 taagcgttta ctctatttca agaatgggca gtcttgcatg gtttcaagac taaaaatgaa
     3061 agcacttgag gcgtctatta aggctttgca ttgacagtaa aagaatgcca tgtggaagcc
     3121 atcatttgtt ttttaatcaa cctcgttgat acc
//
LOCUS       DARYXW010000123         3098 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.124, whole genome shotgun sequence.
ACCESSION   DARYXW010000123 DARYXW010000000
VERSION     DARYXW010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3098)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3098)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3098
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.124"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            284..742
                     /locus_tag="TV191_001810"
     CDS             284..742
                     /locus_tag="TV191_001810"
                     /inference="COORDINATES: protein motif:HMM:NF025561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TnpV protein"
                     /protein_id="HEL1508288.1"
                     /translation="MKETVVLAKKEYILENEIYTPIVKESPFERQGGTYRLEKMEDGA
                     EVLVPNMKMPEKINASKLNRFGKERLKYLKEEKQEEYQIMLMEETLMDHLIDIQEQVE
                     DFLNIEEPRMKEAWKMTTEMQDQDFLKYTGLKKNLDMTLTKMAMEQIIWV"
     gene            628..>3098
                     /locus_tag="TV191_001811"
     CDS             628..>3098
                     /locus_tag="TV191_001811"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEL1508289.1"
                     /translation="MENDHRNAGSGLSEIHRTEEELGYDTNKNGYGTDHLGIDEYRKE
                     NIQKIEQNHVENEEKEVERTSFSFAQNVGVQGRFELPMQQEEIGAVLIHGGNEDNLHL
                     KVLAEYSKEKSMEELADFLQKTFQGGNGYELNGNKVCAWYEMDGIHLSNDVSSRENPM
                     QILPWKDAAIRIGELIDYGKYSTNVEVAEAFSFERAELSEKLWFLKGDLSDEVKNQFL
                     PILNEKQRNGYPEKTEYLTKKLEDKEFRVNLKEEYIEFFKAYKENSNVLRFHNHDLDD
                     ISKRLDDLELPRKEFTSTLIELPAIQGFITEDEIDRYLSSGSNVSGGKERIYNFFREA
                     HTTEERANFLKDEYGTGGQTHALSRARGSSEWHDAKGIKLEKENCKDIILKWNQVVKK
                     IDNLIENGKYIQEDVYTEQESIKTEEEYFDEDTYTEQNSKENEQDWQREQEILLIQDE
                     REVSYEEAEEIYERQAEIEHNAFATGVENNISSTQSNKDYWIVEFNEGSNLIEKNYAG
                     EVVTKKLLDEIKVLDEKIRVHNKTVGEDEYGEMTDEWVGYSKFYFDHIVDGKVEEHFR
                     MDIGDGNEVNQRDFQYLYEQIEPEKENKEYGMDSIDSVIKDILEKESMTVVSSKDDYI
                     KLFPYFRNFVYTDGLRLDEYNPFEDDENISDLIRLTFFQNNDGEYRVVYNNADSLLYS
                     SNVDYFLEKIEAEKVRLEDNIAEIPNEDKIAVKVGNYYAVVEKERVKDISLEETGVRV
                     YPKENNFEGKIYPLYRGSTFEESAKIDKLFDEIAIGMKEVNLTDLNDVFYLENQGLYE
                     ISSDRVTEEKAGYDFEVASFNEQFP"
BASE COUNT         1253 a          343 c          698 g          804 t
ORIGIN      
        1 gcattttccg gtgatataga aaaattagag atgctttcaa atgtttcaag tatgcaggat
       61 attgacagat tacttttctt tacttcaaac aatgtaaaaa gaatacttat ggatataagt
      121 agagaaattt caaaagtgga agaaagagaa aaaatttcag aaattcaaaa aagggagcag
      181 acaaatagta ttgcggagcg ttatactaat gttacagatg aaattaacgg aaataccgaa
      241 attatagaaa atgaaaaaga aagaaatgaa ggaggtttgg aagatgaaag aaaccgtagt
      301 attggcgaag aaggagtaca tcctagaaaa cgagatttat acaccgatcg taaaagagag
      361 tccattcgag agacagggag ggacttacag attggagaaa atggaggatg gagcggaagt
      421 attagttccg aatatgaaaa tgccggagaa aataaacgca agcaaactga accgatttgg
      481 caaggagaga ctgaaatatc tcaaagagga gaaacaagag gaatatcaga ttatgctgat
      541 ggaagaaact ttaatggatc atttgataga tattcaggaa caagtggagg atttcctgaa
      601 tatagaagag ccgaggatga aagaagcttg gaaaatgacc acagaaatgc aggatcagga
      661 ctttctgaaa tacacaggac tgaagaagaa cttggatatg acactaacaa aaatggctat
      721 ggaacagatc atttgggtat agatgagtat cgtaaagaaa atatacagaa gatagaacaa
      781 aatcatgtag aaaatgagga aaaagaagtc gagaggactt ctttttcttt tgctcaaaat
      841 gtaggagttc aaggaagatt tgaattacca atgcagcaag aagagattgg tgctgtttta
      901 attcatggag gaaatgagga taatttacat ttaaaggttt tagccgaata ttctaaagaa
      961 aaaagcatgg aagaattagc tgattttctt caaaaaactt ttcaaggagg aaatggatat
     1021 gaactaaatg gaaataaggt ttgtgcttgg tatgaaatgg acgggataca tttatccaat
     1081 gatgtttcct caagagaaaa tcctatgcag attttaccat ggaaagatgc agcaatacgc
     1141 ataggagaat tgattgatta tggaaaatac agtacaaatg tggaggtagc agaagccttt
     1201 tcttttgaaa gagcagaact ttctgaaaag ctgtggtttt taaaaggaga tctaagtgat
     1261 gaggtaaaaa atcagttttt gccaattcta aatgaaaaac aaagaaacgg atatcctgaa
     1321 aaaacagagt atcttacaaa aaaattggaa gataaagagt ttagagtgaa cttaaaagag
     1381 gagtatatag agttttttaa ggcgtataag gagaactcga atgttttaag atttcataat
     1441 catgatttag atgatatatc aaaacgatta gatgatttgg aactgccaag aaaagaattt
     1501 acctcaacac ttatagaatt accagcaata cagggattta tcacagaaga tgaaattgat
     1561 agatatttaa gcagcggtag caatgtatcc ggcggaaaag aaagaatata taactttttt
     1621 agggaagccc atactaccga agaacgagca aattttttaa aagacgagta cggaacagga
     1681 ggacagactc atgctttatc aagggcaaga ggaagtagtg agtggcacga tgctaagggg
     1741 ataaaacttg aaaaagaaaa ttgtaaggat attattttga aatggaatca ggttgtaaaa
     1801 aaaatagata accttattga aaatggaaaa tatattcaag aagatgtata tacagagcaa
     1861 gaaagcataa aaactgagga agaatatttt gatgaagata cctatacgga acaaaactct
     1921 aaagaaaatg aacaagattg gcaaagagaa caggaaattt tgctgattca agatgaaaga
     1981 gaagtatctt atgaagaggc ggaggaaata tatgaaaggc aagcagaaat agaacataat
     2041 gcctttgcaa ccggtgtaga gaataacata tcgtcaactc aaagtaacaa ggattattgg
     2101 attgtagaat ttaatgaagg ctcaaatctg atagaaaaaa attatgccgg agaagttgtt
     2161 acgaaaaaat tgcttgatga aatcaaggtg cttgacgaaa aaattagagt tcataataag
     2221 actgtcggtg aagatgaata cggagaaatg acagatgaat gggtaggtta ttctaaattc
     2281 tattttgacc atattgtaga cgggaaagta gaagaacact tcagaatgga tatcggggat
     2341 ggaaatgagg taaaccaaag agattttcaa tatctttatg agcagattga accggaaaaa
     2401 gaaaataaag aatacgggat ggatagtata gatagtgtca taaaagatat tttagaaaaa
     2461 gaatctatga ctgtggtatc aagcaaagat gattatataa agttatttcc atattttaga
     2521 aactttgtat ataccgatgg tctaaggctt gatgaatata atccgtttga agatgatgaa
     2581 aatatttcgg atttaattcg actgactttt ttccaaaata atgatggaga atatagggta
     2641 gtctataaca atgcggacag tttactgtat tcaagcaatg ttgactattt tttggagaaa
     2701 atagaggctg aaaaggtaag gttagaagat aatatagctg agataccgaa tgaagataaa
     2761 attgccgtta aggttgggaa ttactatgct gttgtagaaa aagaaagagt aaaggatata
     2821 tccttagaag aaacaggagt tcgtgtttat ccgaaagaaa ataactttga gggaaaaatt
     2881 tacccattgt atcgtggcag cacctttgaa gaaagtgcaa aaatagataa acttttcgat
     2941 gagattgcaa taggcatgaa agaggtcaat ttgaccgatt taaatgatgt tttttatctt
     3001 gaaaatcaag gactttatga aatttcatcg gatagggtaa cggaagaaaa agccggatac
     3061 gattttgaag tggcaagttt taatgaacag tttcctga
//
LOCUS       DARYXW010000124         3091 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.125, whole genome shotgun sequence.
ACCESSION   DARYXW010000124 DARYXW010000000
VERSION     DARYXW010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3091
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.125"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(1..234)
                     /locus_tag="TV191_001812"
     CDS             complement(1..234)
                     /locus_tag="TV191_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF739 family protein"
                     /protein_id="HEL1508290.1"
                     /translation="MVFDYSKLSGRIVEKFGTQYNFALALGLSERSLSLKLNNKVDWR
                     SKEIAQACQELDINENDVGEYFFKQNVHIHEQN"
     gene            442..1209
                     /locus_tag="TV191_001813"
     CDS             442..1209
                     /locus_tag="TV191_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1508291.1"
                     /translation="MSERNLRQVDILEKSKPFQKQLGVKMGRSTLSQYVSGKSVPAQR
                     QLYLLSKTLNVSEAWLMGYDVAIERIPDEKRRATTEISNQPEIVSIYNQLEQPRQEKV
                     LSFANEQLEEQNKVVSTHEELFSVQGVTYAAAASGFGRGFEADEYDTYTVYTDEEPPR
                     YDYAIGIRGDSMLPKYEQGDMLYIVDRGMSTYNGQLCIVVHNGQTYFKKVYTEEDGLR
                     LVSLNKKYNDIFIDYPPAEDTYIKIYDVVGSFTPVEM"
     gene            1223..1453
                     /locus_tag="TV191_001814"
     CDS             1223..1453
                     /locus_tag="TV191_001814"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508292.1"
                     /translation="MTTFTLTIDEKNKYIADYFKRNNIDDSQLTFEQLLTVLEDAEDY
                     AAGMAVLMEQKDNPDYKTYTLQEVADELGITL"
     gene            1453..1740
                     /locus_tag="TV191_001815"
     CDS             1453..1740
                     /locus_tag="TV191_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEL1508293.1"
                     /translation="MYKIEFDPKVKKQLKKLDKTASSKIIRWLYANVDGTSLPRLHGK
                     ALTGDLAGLWRYRIGDYRVICDIQDDKLVILAVHIAHRKQVYKLKLPNNKR"
     gene            1753..2079
                     /locus_tag="TV191_001816"
     CDS             1753..2079
                     /locus_tag="TV191_001816"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508294.1"
                     /translation="MYFDEFKEYVENNSRAHDYFFERALDYQNAKNARRTPAHRRWKE
                     QKVLKEVETMWTNVVKQLYDNIKLNGKFRKRFMHQEEIDEWVSFMNEHEILESFADSM
                     AEIEFE"
     gene            2145..2570
                     /locus_tag="TV191_001817"
     CDS             2145..2570
                     /locus_tag="TV191_001817"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508295.1"
                     /translation="METEKINNVNILRSNNSRLSGYATSASYPLILPIIVEFELYNIK
                     QSKTYLFQITATKINDRRQNNHIKDLLSLSSNQTTVTISAERHNTFFPYEGYGTVATK
                     LDFSFNIDSPGDYCIALTLLDSEGSLLDKHSNYYIFGEE"
     gene            2672..2938
                     /locus_tag="TV191_001818"
     CDS             2672..2938
                     /locus_tag="TV191_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508296.1"
                     /translation="MSQEIYSKSEIDLKFENLETKIDSKFDLLMQKMDDGFEKQRLNT
                     EKMLSDFKLNLVTDQQKNKKEFMYWAIGIIIALAGIAFPIWFGK"
BASE COUNT         1102 a          530 c          578 g          881 t
ORIGIN      
        1 ttagttttgt tcatgaatat gaacattttg cttaaaaaaa tattctccta catcgttttc
       61 gttgatatct aactcttgac aagcttgcgc aatttctttg cttctccagt ctactttatt
      121 attaagtttt aaagatagcg agcgctcaga tagccctaaa gccaaggcaa agttgtactg
      181 tgtgccgaac ttctcaacga tccttccgct gagttttgaa taatcaaaaa ccataggaac
      241 ctcctttctt ttttgttcat gttcatgaac tttatgcttt tatgttacac tttgttttga
      301 actttgtcaa tacacaaagt tcattttttt gaattttttt attgaacttt tgttcaagat
      361 gttttataat taacctataa acatcgaaag gaatctactt ttatgcaatg tagttctact
      421 tcaaatagat taaaacaact gatgtcagaa agaaatttaa ggcaggttga tattttagaa
      481 aaatcaaaac cttttcagaa acaattgggg gtaaagatgg gcagaagtac tctttcgcaa
      541 tacgttagtg gcaaatctgt tccagctcaa cgacaactct atcttttatc taaaaccctt
      601 aacgtaagcg aggcatggct gatgggatat gatgtagcca tagagcgcat acctgatgaa
      661 aaacgtagag ctacgacaga aatatctaat caacctgaaa tagtgtccat ctacaaccaa
      721 ctagaacaac ctagacaaga aaaagtcctc agcttcgcta acgaacaatt ggaagaacaa
      781 aataaagttg tttctacgca tgaagaatta ttttcggttc aaggcgtaac ttacgcggca
      841 gccgcaagtg gctttggtcg tggatttgaa gcagatgaat atgacacata tactgtctac
      901 actgacgaag aacctcctcg ctacgactac gctattggaa ttcgaggaga cagcatgcta
      961 ccaaaatatg agcaagggga tatgctctat attgtagata gaggtatgtc aacatataac
     1021 ggtcaactgt gtatcgttgt tcacaacgga caaacctatt ttaagaaagt atatacagaa
     1081 gaagacggac ttagattagt atctctcaac aagaaatata acgatatttt tattgactac
     1141 ccaccagcag aagatactta tatcaaaatc tatgacgttg tcggcagttt tacacccgta
     1201 gaaatgtaaa ggaggagata ttgtgacaac atttacactt acgattgatg aaaaaaataa
     1261 atacatagct gactacttca agagaaataa tattgatgat agtcagctca cgttcgagca
     1321 gctccttact gtcctagaag atgcagaaga ctatgcggca ggtatggcag tgttgatgga
     1381 acaaaaagac aatcccgact ataaaaccta cacacttcaa gaagtagctg acgaattggg
     1441 tattactcta tgatgtacaa aatagaattc gaccctaaag tcaaaaagca gctaaaaaaa
     1501 ttagataaaa cggcatcttc aaaaattatc cgttggcttt atgctaatgt ggacggtact
     1561 tctctaccta gactgcacgg aaaagcgtta actggtgacc tagctggatt atggcgctac
     1621 cgtataggag attatagggt catctgtgat atacaagatg ataaacttgt tatcctagct
     1681 gttcacatag cccatagaaa gcaagtttac aaactcaaat tgccaaacaa taaacgatag
     1741 aggtttaaag taatgtattt tgacgaattt aaagagtatg tagaaaacaa tagccgtgct
     1801 catgattatt tctttgaaag ggcacttgat tatcaaaatg ctaaaaatgc taggcgaaca
     1861 cccgctcata ggcgatggaa agagcaaaag gtactcaaag aagttgagac tatgtggacc
     1921 aatgttgtca agcaacttta tgacaacatc aagttaaacg ggaagttcag gaaacggttc
     1981 atgcaccaag aagaaattga tgagtgggtt tccttcatga acgaacatga aattttggaa
     2041 tcattcgcag atagcatggc tgaaatagag tttgagtagg aacgtcgcta acggagcgtt
     2101 gatcaaagaa gaattagagt ttttaattag ttaaggagat aagcatggaa actgaaaaaa
     2161 taaataatgt aaatatttta cgaagtaata actcaagact ttcgggatac gcaacaagtg
     2221 cgagttatcc ccttatattg cccattatag ttgagtttga attgtataat attaagcaaa
     2281 gcaaaaccta tctatttcaa ataacagcaa ctaaaataaa cgatagaaga caaaataatc
     2341 atatcaaaga cttactatca ctatccagca atcagactac tgtcaccatc tccgcagaga
     2401 gacataatac attttttccg tatgaaggat acggaacagt ggcaacaaaa cttgatttct
     2461 cgtttaacat agacagtccg ggtgactatt gcattgcgct tacacttttg gatagcgagg
     2521 gatctttatt agataagcac tcaaattatt acatttttgg agaagagtaa ttatgagtga
     2581 atatcttaca ctatataaac ccgaaacctc caacattgat gccaaaaata atggtataat
     2641 agacttagaa aagagtcagg aggaatctat tatgtcacaa gaaatttata gcaaatcaga
     2701 aatagatttg aagtttgaaa atcttgaaac gaaaattgat agcaaattcg atttattgat
     2761 gcagaaaatg gatgatggtt ttgaaaaaca acgattaaat acagaaaaaa tgttgtcaga
     2821 tttcaagcta aatctagtga ctgatcaaca gaaaaataaa aaagaattta tgtattgggc
     2881 tatcggtatt attattgcct tagcaggtat tgcttttccg atttggttcg ggaaataaaa
     2941 aaagccccac gctctcaaag tttggcgact ctgagcgtga ggcgaaaccg tataagaaac
     3001 aaccattaaa aaggtcgttt tcttgtacct aaaattatat cacacaaagg tggtgatgcc
     3061 aatatccttt caaacgacct cgtccaaaag t
//
LOCUS       DARYXW010000125         3076 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.126, whole genome shotgun sequence.
ACCESSION   DARYXW010000125 DARYXW010000000
VERSION     DARYXW010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3076)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3076)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3076
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.126"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            57..776
                     /locus_tag="TV191_001819"
     CDS             57..776
                     /locus_tag="TV191_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1508297.1"
                     /translation="MPRFSKAFQYMGATTMLGLSLLAANVNANTNADTVTVDLTYTAY
                     SNLTNEQKAGIQKGTPNEVPIQDKLHYVLVYDKSCGVTASPKGMMSTPKANAKVLPKT
                     GGAADGLVGLAVGLGLLSVSGYLIYKNRKSGSYVLIALLVAGGATTAVSAVDVVRHLN
                     DIVTKTTVKGVSFTYTPEEKVDDYCYVGYIVTQENSPAPTPEPKPDPVPTPEPKPEPK
                     LDPVPTPEPTPDPEYFEAIPQ"
     gene            complement(888..3074)
                     /locus_tag="TV191_001820"
     CDS             complement(888..3074)
                     /locus_tag="TV191_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEL1508298.1"
                     /translation="MKNFKTFITSFINTRLGFVLTLLFCFWIKTLWAYHADFSLDLGN
                     AYQVFLTIINPIPLALLLLGFTLYIKNTRAFYISSWIVYIILNLLLISNSIYYREFSD
                     FITVSAMLASSKVSAGLGDSALNLLRIWDIVYVLDFIILISLSVTKTIKKDPRPFNKR
                     ASFAVTALSCLLLSVNLFLAEIDRPELLTRGFSNTYIVRALGLPAFTIYSGNQTYQAQ
                     KERNGATAEELVDVKQYVKNHYAAPDPQYFGIGKGKNVIVIHLESFQQFLIDYKLKDD
                     DKDYEVTPFINSLYHSNATLAFSNFFHQVKAGKTSDAETMMENSLFGLNSGSFMVNYG
                     GENTQFATPSILAQNGGYTSAVFHGNVGTFWNRNNAYKQWGYHYFFDSSYFSKQTDKN
                     SFQYGLNDKYMFRDSIKYLEQLQQPFYTKFITVSNHYPYTSLRGESSEEGFPLAKTDD
                     ETINGYFATANYLDSALKSFFDYLKATGLYDNSIFVLYGDHYGISNSRNVSLAELLGK
                     DPETWSEYDNAMLQRVPYMIHIPGYTNGGIKETFGGEIDSLPTLLHILGIDTSKMVQL
                     GQDLLSPQNSQMVAQRTSGTYITPDYTSYSGRLYNTQTGLEITNPDEMTMAKVKEIRA
                     AVAQQLAASDAIQTGDLLRFDTDNGLKPVDPTTFIYTKQLKQLKEISEKLGSHSTSIY
                     SKNGNKSTQKLFKAPSYLELNPKEAEKPESTSSSDPKEESVKEQSQ"
BASE COUNT          907 a          571 c          680 g          918 t
ORIGIN      
        1 agatgccttt ttagttattg gttttattct acaaaacatt aaggagaata gttataatgc
       61 cacgtttttc taaagcgttt caatacatgg gagctacaac gatgttaggt ctatctttgc
      121 tagcagctaa tgtcaatgcc aacactaatg ctgatacggt aacggtagat ttgacctata
      181 cagcctattc taatctgaca aatgaacaaa aagcaggcat tcaaaaaggc actccaaatg
      241 aagtacctat ccaagataaa ttgcattacg ttcttgttta cgacaaaagc tgtggagtga
      301 cagcatctcc aaaaggaatg atgtctaccc ctaaggctaa cgctaaggtc ttgcctaaaa
      361 cgggtggtgc agcagatggt ctggttggtt tggcagtagg gctaggctta ctaagtgttt
      421 caggctatct tatttacaaa aataggaaaa gcggtagcta tgtgttgatt gccttgttgg
      481 tagctggtgg tgcgacaaca gctgttagtg cagttgatgt ggtacgtcat ctcaatgata
      541 tcgtcactaa gactacggtt aagggggtaa gctttactta cactccagaa gaaaaggttg
      601 atgattactg ttatgtgggt tatattgtga cgcaagaaaa tagcccagca ccgacacccg
      661 aacctaagcc agatcctgtg ccaacaccag aaccgaagcc tgagcctaag ctagatcctg
      721 tgccaacacc tgaaccgaca ccagatccag aatactttga ggccattcct caataaaagt
      781 gtcagaacta aaaagccctc attaagttgt aacgctcaat gaaggctttt agcttgcttt
      841 tagtcttcta cgagagcgat cctagtgagg cttgctttag acatccacta ctgactttgt
      901 tccttaacgg attcttcttt agggtcagaa gacgaagtag attcaggttt ttcggcttct
      961 ttaggattta actccagata agaaggtgct ttaaagagct tttgagttga tttgttgcca
     1021 tttttactat aaatgctggt tgaatgtgat cctaatttct ctgatatctc tttgagttgt
     1081 tttagctgct tggtataaat gaaggttgtt gggtcaacag gtttcagacc attatcggta
     1141 tcaaagcgta gtaggtctcc tgtttggata gcgtcactag ctgctagctg ctgagcaacg
     1201 gctgctcgta tttctttgac cttagccatt gtcatctcat cagggtttgt aatttccaag
     1261 cctgtttgag tgttgtaaag gcgaccgcta tagctagtgt agtctggcgt gatataagtt
     1321 ccagaggttc tttgtgctac catttgacta ttttgtggcg acaagagatc ctgtcctagt
     1381 tgaaccatct tgctggtatc aatgcccaag atatgcagta aggttggtaa ggaatcaatt
     1441 tctccgccaa aggtttcttt gatcccgcca ttggtatagc ctggaatatg gatcatatat
     1501 ggtacacgct ggagcattgc attgtcatat tcggaccaag tttcagggtc tttacctagt
     1561 aattctgcca agctgacatt tctggaatta gaaataccat agtggtcacc atatagaaca
     1621 aagatagaat tgtcataaag tcctgtcgcc ttgagataat caaaaaatga tttcaaggct
     1681 gaatccagat agttagctgt agcaaagtaa ccattgatgg tttcatcatc ggttttggct
     1741 agtggaaagc cctcttcact gctttcgcct ctaaggctgg tgtaagggta gtggttgctg
     1801 acggtaataa acttagtgta gaagggttgt tgaagctgtt caaggtactt gatagaatct
     1861 ctaaacatgt atttgtcatt taggccatac tggaaagagt ttttatcagt ctgttttgaa
     1921 aaatagcttg aatcaaaaaa gtaatgatag ccccattgct tataagcatt attgcgattc
     1981 cagaaggttc ctacattccc atgaaagacg gcactagtat agccgccatt ttgtgctagg
     2041 attgatggtg tggcgaattg tgtgttttcg ccgccataat ttaccataaa agaaccactg
     2101 tttaagccaa ataatgaatt ttccatcatg gtctctgcat cagacgtttt tccagccttg
     2161 acctgatgga aaaagttaga gaaggctagt gtggcattgg agtggtagag ggaattaata
     2221 aaaggtgtga cctcatagtc cttgtcgtca tccttgagct tgtaatcaat aagaaattgt
     2281 tggaagcttt ccaagtggat cacaatgaca ttttttccct taccgattcc aaaatattga
     2341 ggatcaggtg cggcgtagtg gttcttgaca tattgcttaa catcgactaa ttcttcagcg
     2401 gttgctccgt tacgctcttt ttgtgcttga taggtctggt ttccgctgta aatggtaaaa
     2461 gcaggcaatc caagcgctct aacgatatag gtatttgaaa atcctctagt cagaagctcc
     2521 gggcggtcaa tctctgcaag aaacagatta acagataaga gcaagcaaga cagtgctgta
     2581 acagcaaagg aagcccgctt gttaaaagga cgcgggtctt ttttgatggt cttagttact
     2641 gataaactaa tcagaatgat gaaatcaagg acgtaaacaa tatcccaaat gcgcaaaagg
     2701 tttaaagcag agtctcctaa accagcagaa accttactac tggctagcat agcactaacc
     2761 gtaatgaaat ctgaaaactc tcggtaataa atagaatttg atattaacaa gaggttaagg
     2821 ataatataga cgatccaaga gctgatataa aaggccctag tattcttgat ataaagggta
     2881 aatcccaata gtaacaaagc tagagggatt gggttaataa ttgttagaaa gacctgatag
     2941 gcatttccca aatctagtga aaagtcagca tggtaagccc atagggtttt tatccaaaag
     3001 cagaagagaa gcgttagcac aaagcctaat cttgtattga taaagcttgt gataaatgtt
     3061 ttaaaattct tcacag
//
LOCUS       DARYXW010000126         2776 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.127, whole genome shotgun sequence.
ACCESSION   DARYXW010000126 DARYXW010000000
VERSION     DARYXW010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2776)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2776)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2776
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.127"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(98..1600)
                     /gene="pyk"
                     /locus_tag="TV191_001821"
     CDS             complement(98..1600)
                     /gene="pyk"
                     /locus_tag="TV191_001821"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEL1508299.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKYGEDGYWAGQLDVEQSAKKIAE
                     LIEAGANVFRFNFSHGDHKEQGDRMATVRLAEKLARQKVGFLLDTKGPEMRTELFADD
                     AKEYSYVTGERIRVATAQGIQSTRDMIALNVAGALDIYDEVEVGHTILIDDGKLGLKV
                     IEKDIAKREFIVEVENDGIIAKQKGVNIPNTKIPFPALAERDNADIRFGLEQGLNFIA
                     ISFVRTAKDVEEVREICRETGNEHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVFQKMIITKVNAAGKAVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPVEAVRTMATIDKNAQTLLNEYGRLDSSAFPRTNKTDVIASAVK
                     DATHSMDIKLVVTITETGNTARAISKFRPDADILAVTFDEKVQRALMINWGVIPVLAE
                     RPASTDDMFEVAERVALETGLVQSGDNIVIVAGVPVGTGGTNTMRVRTVK"
     gene            complement(1662..2675)
                     /gene="pfkA"
                     /locus_tag="TV191_001822"
     CDS             complement(1662..2675)
                     /gene="pfkA"
                     /locus_tag="TV191_001822"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEL1508300.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRKAISEGMEVYGINRGYAGM
                     VDGDIFPLGSKEVGDKISRGGTFLYSARYPEFAQLEGQLAGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAVGIPGTIDNDIAGTDYTIGFDTAVNTAVEAIDKLRDTSSSH
                     GRTFVVEVMGRNAGDIALWAGIASGADQIIVPEEEFDIHKVVSTIKDDFENRGKNHHI
                     IVLAEGVMSGEAFAQQLKEAGDESDLRVTNLGHILRGGSPTARDRVIASWMGAHAVEL
                     LKEGKGGLAVGIHNEELVESPILGSAEDGALFSLTDEGNIVVNNPHKARLDYAALNRS
                     LAQ"
BASE COUNT          809 a          687 c          485 g          795 t
ORIGIN      
        1 atgatatgac taataaaaaa agcaaacaat ttttaagtat cattgtttgc cttaaattat
       61 ctgatagagc aaaatagcta aagcttatgg aaagctatta ttttacagtg cgaacacgca
      121 ttgtatttgt accacctgta ccaactggca cacctgcaac aataacgata ttatctcctg
      181 attgcaccaa accagtctca agagctacac gctctgctac ctcaaacata tcatctgttg
      241 atgctggtct ttcagcaagc actggaatca caccccagtt aatcatcaag gcacgttgaa
      301 ccttttcatc aaaggtcaca gccaagatgt cagcatcagg acggaactta gaaatggcac
      361 gagctgtgtt tcctgtttca gtgatggtca caacaagctt gatatccatt gagtgtgttg
      421 catctttaac agctgaagca atcacgtcag ttttattggt acgtgggaag gcagatgaat
      481 ctaaacgacc atactcatta agaagagttt gtgcattttt atcaattgta gccattgtac
      541 gaactgcttc aacagggtat ttaccatttg ctgattcacc agaaagcatt gtcgcatctg
      601 taccgtcaat aaccgcgttg aaaacgtcag atacctctga acgagttgca cgtggttttt
      661 cagtcattgt ttcaagcatg ttagttgcgg tgatgactgc tttacctgct gcatttacct
      721 tggtgataat cattttttgg aagactggaa ccatttcaaa tggcacctca atccccatat
      781 caccacgagc aatcatgata ccatctgcag cttcgatgat ttcatcaagg ttatcaatac
      841 cttgttggtt ttcgatttta gcaaataatt gaacatgctc attgcctgtt tcacgacaaa
      901 tctcacgaac ctcttcaacg tccttggcag tacgaacaaa tgaaatagca ataaagttaa
      961 gaccttgctc aagaccaaaa cgaatatcag cattatcacg ttctgctaag gctgggaaag
     1021 gaatcttggt attagggata ttaacaccct tttgctttgc aatgatgcca tcattttcaa
     1081 cctcaacgat gaactcacgc tttgcaatgt ccttctcgat aacctttaag ccaagctttc
     1141 catcgtcaat aagaatagtg tggccaacct caacctcatc ataaatatca agagcaccag
     1201 ctacattcaa ggcaatcata tcacgagttg attgaatgcc ttgtgctgtc gcaacacgaa
     1261 tacgctcacc agtcacatag ctatattctt tggcatcgtc agcaaacaat tctgtacgca
     1321 tttctggtcc ttttgtatcc aaaaggaaac caaccttttg acgtgccagc ttttcagcaa
     1381 gacgaacagt agccatacgg tcaccctgct ctttgtggtc accatgtgag aagttaaagc
     1441 ggaaaacatt agcacctgct tcaatcaatt cagcgatctt tttagctgat tgttcaacgt
     1501 ccaactgacc agcccaatag ccgtcctcac catatttttt accaccgcga atttcaaccg
     1561 caggaccaag tgttgcaaca atttttacac gtttattcat tttattatga aactccctta
     1621 ttttttagtt gattaacaaa gattaccaga tcttacttat cctattgtgc taatgaacgg
     1681 ttcaaagcag catagtctaa gcgagccttg tgcgggttat taacaacaat gttaccctca
     1741 tcagtaaggc tgaacaaggc accgtcctct gcacttccaa gaatcggact ttcaacaagc
     1801 tcttcattat gaataccaac agccaagcca cctttgcctt ccttgagcaa ctcaacagcg
     1861 tgcgctccca tccatgacgc aatcacacga tcacgcgcag ttggagagcc accgcgaagg
     1921 atatgaccaa ggtttgtcac acgaaggtca ctttcatctc cagcttcttt tagctgctgc
     1981 gcaaaggcct cgccactcat aacaccctca gctaaaacga taatatggtg attttttcct
     2041 ctattttcaa aatcgtcttt aattgttgag accactttat gaatgtcaaa ttcctcttca
     2101 ggaacgatga tttgatctgc tccacttgca atacctgccc aaagtgcgat atcacctgca
     2161 ttgcgtccca tcacttcaac aacaaaggtc cgtccatgac ttgatgaggt atcgcgaagc
     2221 ttatcaatag cctctaccgc agtattgacc gcagtgtcaa atccgatagt atagtctgtt
     2281 ccagcaatat cgttatcaat cgtccctggg atacctactg cagggaagcc atgctcagtc
     2341 aagcgcatcg caccatggta agaaccatca ccaccaatga caactacccc ttcaatgcca
     2401 tgctttttta gctgctcaat accagccaat tgcccctcaa gctgagcaaa ctctgggtag
     2461 cgagctgaat aaaggaaggt cccgccgcga gaaatcttat caccaacctc ttttgagcct
     2521 agtggaaaga tatcaccatc aaccatacca gcatagccgc ggttaatacc atagacttcc
     2581 attccttctg aaattgcttt acgaacaact gcacgaatag cagcattcat accaggggcg
     2641 tcaccaccac tggttaaaac agcaatacgt ttcatttttt ggtactcctt taattaattt
     2701 aacgttttta ttatagcaca ttcgtttgca aattacttca ctaattcgct atttttatcg
     2761 aaaaaccgtt ttcaac
//
LOCUS       DARYXW010000127         2736 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.128, whole genome shotgun sequence.
ACCESSION   DARYXW010000127 DARYXW010000000
VERSION     DARYXW010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2736)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2736)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2736
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.128"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(106..612)
                     /locus_tag="TV191_001823"
     CDS             complement(106..612)
                     /locus_tag="TV191_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508301.1"
                     /translation="MKRKILLLMMLLVGVFIFSKRYELYYFFQGKEYLRPNESIELAV
                     RPKYEQIEYSSDLYLESDEKVLLKLEGRDIWSEYIYRRTDSYLSKIGYRYSITEQVIE
                     KYDSTKDNGVVIVEAGHKGATIDGDGLIVPLKGKRKYSVTEDHDYSITITNLSDQPVA
                     FRAIVADR"
     gene            complement(609..2015)
                     /locus_tag="TV191_001824"
                     /pseudo
     CDS             complement(609..2015)
                     /locus_tag="TV191_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515913.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2006..2365)
                     /locus_tag="TV191_001825"
                     /pseudo
     CDS             complement(2006..2365)
                     /locus_tag="TV191_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515008.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2377..2643)
                     /locus_tag="TV191_001826"
     CDS             complement(2377..2643)
                     /locus_tag="TV191_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04197 family type VII secretion effector"
                     /protein_id="HEL1508302.1"
                     /translation="MSDTITSSPVAASAAISELVGVDTSRVHQQSVAFSVTKGIAGME
                     KGRQVSNQLLQAVSDFSQAVLIQANKFPQLAAKLEKRDLEEATR"
BASE COUNT          709 a          645 c          514 g          868 t
ORIGIN      
        1 gtgacccaac aaaccatcac tagaagctat aaggggagct tttctatgcc taacaaaaat
       61 ctaaaatcaa taacagaaaa acctaaagca gttcatgcgc acatactacc tatctgctac
      121 tattgctcta aaagcaaccg gctgatcgga caggttggta atggtgatac tatagtcatg
      181 atcttctgtc acactatatt ttctcttccc cttcaaggga acgatgaggc catctccatc
      241 aatagtagct cccttgtgtc cagcttctac aataactaca ccattatcct tagtggaatc
      301 gtatttttca ataacctgtt ctgttataga ataccgatat cctatcttac taagatagct
      361 gtctgtccgt ctataaatat attcagacca tatatcacga ccttctagct tcagtagcac
      421 tttttcgtcg ctttctaggt ataggtcaga ggaatattct atttgttcat actttggtct
      481 caccgcaagc tctatactct catttggcct tagatattct tttccttgaa aaaaatagta
      541 aagctcatag cgtttggaga agatgaaaac acctaccagc aacatcatta ataacaggat
      601 ttttcgcttc attttgactt cttccttttc atataaccat ctatacctgc ttggatcatt
      661 tgagtatcac cctcattgtc tccatagtga cctgatgata agttctttaa ccactttggt
      721 atatccttat cagaaaagac ctgggcaatc tcagccgccg tttttaaata agtccctgaa
      781 gcatctaaaa agcctgtacc aacataacca tagaggtagt tgccagcata gtcgcctggc
      841 aattctgatt cccactgtct tgaccagaca gaatagttat ggccatgata ggtccttgac
      901 ttcaaatcca agggctgacc cgtattgaca aggtcataaa attgtttgtt gtcaagtatt
      961 gcagcactta attgacttcc agctacctgt gaaaggtagg gagcattgac attcactgat
     1021 aggatatcat ctcccatctt gttgacaatc aaacgaaaat taatacccga cgattgtaat
     1081 tttttcccta ggtcttcctc aatttccttt gcatatttat tatttttaag gtctcactct
     1141 ccatcataat tgcttctcgc cttccaatag tcatcaaagg ctgttttatt gagaaaatag
     1201 aggtaatcct cataggcagc tacaagtcgc tctgattttt gtagtggcct ttcagagctg
     1261 cttttgatgg ttttaatggt ctgagtcagt atgttgtgat aatggttttg agtgtacttt
     1321 gaggcattga cagggctaat cttttgattc ttcaggctag tcacccagct catatctagg
     1381 ccagcagtcg agtagctgcc gtcgctgctc atgaagacct gactgagctg tgttgcgccc
     1441 tgaatggcta accgcaaaat aactaagctg tccctaaagc agtctgaggt ttgagttaga
     1501 aaccattcaa ggctttccaa tttggtcgta acatctcgaa tccctatttc cagctggttt
     1561 ttggcatggt atagtgtaga ggtatcagac caaagggtgc catagtctcc ggttaaaaga
     1621 ctactgacct gcttcataaa cgattcgttt tcatcaatct gtgcttggat cacttgcact
     1681 tgccgttctc ttagcctctt cagctcggtt aagtgatcac gatccagggt tccgtatctg
     1741 gcaatctgag catctgccct ttgataggtg gtcaactcca cttggatagc atcaatcgct
     1801 gcttgtagct ttttgataga gggaatgatg atcgctgtaa aaagtcccct acctgctgta
     1861 taggctgctc cctgtagctc tcccgaatcc agactagcaa tgagatggtc gcaaccactt
     1921 gataacctgt ccgttatttc attggctatt tggatattgt ttgtcatggc ttgaatcaag
     1981 gcctttgact ctgctgcact gtaggtcact cccatcgtaa acggctcctt tcaccgataa
     2041 gctcttcttt gtccctctct agtctacgac gaacccccat cgtatagatt gacacgtgat
     2101 ccagatgctc atcaacatag cgatccattt gtctgatcaa gtggtcattg gcctcttgct
     2161 ctgcgtactt tccagcttag tcctcaggca tatggttcaa tagggactca agggcaaaag
     2221 agaggtgctg acagtctgct tgaatctccg agactgcttg ttcatgccgt cgtttcatcg
     2281 acaaaagatc ctcctctagc cactccagct cattgatctg tcgggttagg gcaagaaatt
     2341 tttcttcaga ttcttctttg atcatgactt attcccctat cttgttgctt cctctaggtc
     2401 tcttttctct aatttggccg caagctgagg aaatttatta gcctgaataa ggactgcctg
     2461 actaaagtcg ctgacagcct gcagcagttg attagagacc tgacgtccct tttccatacc
     2521 tgcaataccc ttggtcacac taaatgcaac ggactgttgg tgaaccctac tggtgtctac
     2581 acctaccaat tcactaatag cagcagaagc agccacaggg cttgatgtaa tggtatcact
     2641 catacaattt ctcctttata acccttatgt cttttattat atcacaggat aatagccatt
     2701 gtgcttatag ctcttaccta aataatagca actgat
//
LOCUS       DARYXW010000128         2496 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.129, whole genome shotgun sequence.
ACCESSION   DARYXW010000128 DARYXW010000000
VERSION     DARYXW010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2496
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.129"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(171..461)
                     /locus_tag="TV191_001827"
     CDS             complement(171..461)
                     /locus_tag="TV191_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508303.1"
                     /translation="MLIPITEYYIEEEYAYALRLMRQMLERQRIATVARLANSQGEAI
                     KKTFKDQIKATASQTKESLQIMEGQLDTAIKGAVRDQLEQVVKKKLPKYNKL"
     gene            complement(442..834)
                     /locus_tag="TV191_001828"
     CDS             complement(442..834)
                     /locus_tag="TV191_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508304.1"
                     /translation="MADRIVEEVAIYRKLREMDDAEQDFLRQKKGYQKREDSLSERRH
                     VLDDLINSEYQKMSVFLKRLDLSANAASDFFKELDRLKDQSNAEFHLQRAALEEERAQ
                     STKTFRQEQDQRETELLDMRRAYANTNN"
     gene            complement(816..2105)
                     /locus_tag="TV191_001829"
     CDS             complement(816..2105)
                     /locus_tag="TV191_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508305.1"
                     /translation="MMISDSSYKKLSEQVYNVEPSKAKSNDAPIVLKGNRLIDDKTGK
                     QYRVLLVQDNNNDAHKINDNGMQAMAVAPIVQGDVDTSQVVIAYAGTNAADSRDLDTD
                     WQLLIRGNQDDLVSGNLDGGNFVIAENQLRSAQKFYQQVKRKYPHSALTTTGHSLGAY
                     LALIVAAEHKIPATTFNGPDPVRGMSAEAITWVKANSNMYNNFRINFDGIGNFGAYFG
                     TDDLAISRNVDAMLLSANPLYYHDLGAYRFNQKGQIVDRDGKLIGTQYLVSRAYLTVL
                     ASKKRMSSYNQLKKHWQSTGKGISSSEELFLDAAQGMILGSSMAKVAREGADEALDHK
                     TVADAKLMEVWSAIDFNAFHELPYYEVQALFASYGITYDRFVRDFQDYTQSKVSKLSA
                     LATDFENLNRDIQTVIDSKLETDQQLAGEFRAWQTEL"
     gene            complement(2107..>2496)
                     /locus_tag="TV191_001830"
     CDS             complement(2107..>2496)
                     /locus_tag="TV191_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508306.1"
                     /translation="IGGLLMVFSLNGKRTEEQQKKDLETSIAKLLVHDYEDVKEVKFT
                     GWGRSRETGSWGTIVVINGENEIGFSFDGLSGLADISGRSYHPDTFKLVEKNSLEEMG
                     PVKYRIKDIEKVSLEGVSITYSREKRS"
BASE COUNT          645 a          610 c          461 g          780 t
ORIGIN      
        1 tcagtacact ggtcctctct cgtctttagc tatcggtcac tctgtataca attatcccct
       61 tttaaaaata acaggacaaa agctctggag gctgatcgcc ttttttgatc atacttgctt
      121 ggtaggtatt gattgaaccc ctacggtctc ttataaatga caccatttga ctatagcttg
      181 ttgtattttg gcagcttctt ctttacgacc tgctccagct gatctctgac cgctcctttt
      241 atggccgtat ctagctgccc ttccatgatc tgaaggcttt ccttagtttg gctggcagtc
      301 gctttgatct ggtctttaaa cgtttttttg atcgcttcac cttggctgtt cgcaagccta
      361 gccactgtgg caatcctttg acgctccagc atttgacgca ttagcctcag ggcataggcg
      421 tattcttctt cgatataata ctcagttatt ggtattagca taagctctcc tcatatctaa
      481 taactctgtc tctctttgat cctgctcttg acgaaaagtc ttggttgact gtgctcgctc
      541 ctcttcaaga gctgcccgct ggaggtgaaa ctctgcgttg gattgatcct ttaagcgatc
      601 tagttccttg aaaaaatctg acgcagcatt ggcagatagg tctaaacgct tcaaaaaaac
      661 actcatcttc tggtactcag agttgatcaa atcatctaag acatgtcttc tttcggataa
      721 gctgtcttca cgcttctgat agcctttttt ctggcgcaga aagtcctgct cggcatcatc
      781 catctcccgc agcttacgat agatagccac ttcctctaca attctgtctg ccatgctcta
      841 aactctcctg ctaactgttg atccgtttca agcttgctat caataactgt ctgaatatct
      901 ctattcaggt tttcaaagtc tgtggccaag gctgacagct tgctgacctt ggattgagta
      961 tagtcctgaa agtctcggac gaagcggtca taagtgatcc cataagaagc aaacaaggct
     1021 tgcacctcat aatagggcag ctcatgaaaa gcgttaaaat caatcgccga ccacacttcc
     1081 ataagctttg cgtcggcaac cgttttatga tccagtgcct catcagcccc ctctcgagca
     1141 accttagcca tggacgagcc taggatcatt ccctgtgccg catctaaaaa gagctcctca
     1201 gaactactga tccccttacc ggtagactgc cagtgttttt tgagctgatt gtagcttgac
     1261 atacgctttt ttgaggcaag gacagttaaa taggcccgac tcacaaggta ttgtgttcca
     1321 atgagcttac cgtctctatc tacaatctga cccttttgat taaaacgata agctcctaaa
     1381 tcgtgataat acaaggggtt ggctgataag agcatagcat cgacattccg agaaatagcc
     1441 aaatcatcag ttccaaaata ggcaccaaaa ttgccaatgc catcaaaatt aatgcggaaa
     1501 ttattgtaca tattgctatt agccttaacc catgtgatag cttcagctga catgccgcga
     1561 acagggtctg gaccattaaa ggttgttgct gggatcttat gttctgcggc gactattagt
     1621 gctagataag ctccgagaga gtgacctgtg gttgttaagg cagaatgagg gtactttctt
     1681 ttgacttgtt gataaaactt ttgagcagat cgtaattggt tttcggcaat aacaaaattg
     1741 ccgccatcaa gattgccgct gactaaatca tcttgattgc cccgaatgag cagctgccaa
     1801 tccgtatcaa gatctctgga atccgcagca tttgtccctg cataggcaat cacaacctgg
     1861 gaggtatcga catcaccttg aacaataggg gctacagcca ttgcttgcat accgttgtca
     1921 ttgattttat gggcatcgtt gttattatcc tgaactaaga ggactcggta ttgcttaccc
     1981 gtcttatcat cgataagacg atttcccttt aaaacaatag gggcatcatt tgacttagct
     2041 ttactaggtt cgacattata gacctgttct gacaacttct tataactact atcggatatc
     2101 atcatattaa ctccttttct cacgagaata cgtaattgac actccctcta aagaaacttt
     2161 ttcaatgtct ttaattctat atttcacagg ccccatttct tccagactat ttttctcaac
     2221 taacttaaaa gtatctggat gataagagcg cccactaata tccgctaatc ctgacaaacc
     2281 atcaaacgaa aagcctattt cattttctcc atttataact actatcgttc cccacgaacc
     2341 tgtttcccga gaacgtcccc agcctgtaaa cttaacttct ttgacatctt catagtcatg
     2401 aaccagcagt ttagcaatac tagtttctaa atcctttttt tgttgttcct ctgttctttt
     2461 gccattcaaa ctaaaaacca taagcagccc tcctat
//
LOCUS       DARYXW010000129         2473 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.130, whole genome shotgun sequence.
ACCESSION   DARYXW010000129 DARYXW010000000
VERSION     DARYXW010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2473)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2473)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2473
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.130"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            51..1004
                     /locus_tag="TV191_001831"
     CDS             51..1004
                     /locus_tag="TV191_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1508307.1"
                     /translation="MNFEKIEQAYELILENSQLIENDLKTHIYDAIVEQNSFYLGAQG
                     ASPQVAKNIETLKALQLTKEEWRQAYQFVLIKAGKTEPLQANHQFTPDAIGFIMLYIL
                     ETLSSQESLDVLEIGSGTGNLAQTILNHSHKSIDYLGIELDDLLIDLSASIAEIMGSS
                     AQFIQEDAIRPQLLKESDLIISDLPVGFYPNDDIASRYQVASSDEHTYAHHLLMEQAL
                     KYLKKDGFAIFLAPVNLLSSPQSHLLKQWLKGYAQVVALITLPEAVFGNPANAKSIIV
                     LCKQSNRFAETFVYPIRDLKSVDNVRDFMENFKNWKRDNVI"
     gene            1064..2263
                     /locus_tag="TV191_001832"
     CDS             1064..2263
                     /locus_tag="TV191_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEL1508308.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEEKVLAQGIIERIGLTDSISTV
                     KYDGKKEEHILDIPDHTEAVKRLLNDLIHFGIIGTYDEITGVGHRIVAGGEYFKESVV
                     VDDKVVEQVEELAALAPLHNPGAAAGIRAFRKILPDITSVCVFDTSFHTTMQKHTYLY
                     PIPQKYYTDYKVRKYGAHGTSHKYVAEEAAKMLGRPLDELKLITAHVGNGVSITANYH
                     GQSVDTSMGFTPLAGPMMGTRSGDIDPAIIPYLIAQDPELKDAADVVNMLNKQSGLGG
                     VSGISSDMRDIEAGLQANNPDAVLAYNIFIDRIKKFIGQYFAVLNGADALVFTAGMGE
                     NAPLMRQDVVNGLSWFGMEIDPEKNVFGYRGDISTAASKVKVLVISTDEELCIARDVE
                     RLKQTIS"
BASE COUNT          730 a          440 c          557 g          746 t
ORIGIN      
        1 tggctagtgg tattcttttc atttcagcct tattttgata tgatagacgt atgaattttg
       61 aaaagattga acaagcctat gagcttatat tagaaaatag ccagctgatt gaaaatgatt
      121 taaaaacgca tatctatgat gctattgttg agcagaattc tttttatctg ggagcccaag
      181 gagcaagccc tcaggttgct aaaaatattg agacgttgaa ggccttgcag ttaaccaagg
      241 aggagtggcg ccaggcttat cagtttgttt tgatcaaggc tgggaaaaca gagccattac
      301 aggccaacca ccaatttacc ccagacgcga tcggctttat catgctttat attttggaga
      361 ccttgagctc acaagagtca cttgatgtgc ttgagattgg cagtggaaca ggtaatttag
      421 ctcaaactat tttaaaccac tcacataaga gcattgatta tttaggcatt gagcttgatg
      481 atttactaat tgatctatca gctagtatcg ctgaaatcat ggggtcatca gcccagttta
      541 ttcaagagga tgctatcaga cctcagctgt taaaagaaag tgatctcatc attagcgatt
      601 tgccagttgg tttttatcct aacgacgata ttgctagcag gtatcaggtg gctagctcag
      661 atgagcatac ctatgcccat catttactga tggagcaagc cttaaagtac ctgaaaaaag
      721 atggctttgc tattttctta gcaccggtaa atcttttgag cagcccacaa agtcacctct
      781 taaaacaatg gctgaagggc tatgctcagg ttgtggcctt gattactttg cctgaggctg
      841 tgtttggaaa tccagctaat gcaaaatcga ttattgttct ttgtaagcaa tcgaatcgct
      901 ttgcagaaac ctttgtttac cccattaggg atttgaaatc tgttgataat gttcgtgatt
      961 ttatggaaaa cttcaaaaat tggaaacggg ataatgttat ttaagagaat tttttgatat
     1021 aatagaaaag cattgcagaa aacgatttca agagaggtaa aacatgtcaa agacaattgc
     1081 aattaatgca ggaagctcca gcttaaaatg gcagctatat caaatgccag aggaaaaggt
     1141 attagcacag ggaattatcg aacgtatcgg tctgacagac tcaatctcta ctgttaaata
     1201 cgatggcaaa aaagaagagc atattcttga tattccagat catacagagg ctgttaagcg
     1261 cttgttgaat gatttgattc attttggcat tattggtacg tatgacgaga tcacaggtgt
     1321 tgggcaccgt attgttgcag gtggtgaata cttcaaggaa tctgtggttg ttgatgataa
     1381 ggttgttgag caggttgagg agttagcagc cttggcaccc ttgcacaatc cgggggcagc
     1441 agcaggtatt cgtgcctttc gtaagatttt gccggacatt acgagtgttt gtgtgtttga
     1501 tacttcgttt cataccacaa tgcaaaagca tacctacctt tatccaattc ctcaaaaata
     1561 ttatacagat tataaggttc gcaagtacgg ggcgcatggg actagccata aatatgttgc
     1621 tgaggaagca gcaaaaatgc tgggtcgccc tctagacgaa ttaaagctca ttacagccca
     1681 tgttggtaat ggtgtgtcta tcacagccaa ttatcatggt cagtcagtgg atacctctat
     1741 gggctttaca ccgcttgctg gtccgatgat ggggacacgc tctggtgata ttgatcctgc
     1801 tattattcct tatttgattg ctcaggatcc tgagctaaag gacgcagcag atgtggtcaa
     1861 tatgcttaac aagcaatctg gattaggtgg tgtgtctggt atttccagtg atatgcgtga
     1921 tattgaggct ggcttgcagg ctaacaatcc agatgccgtc ttagcttaca atatctttat
     1981 cgatcgtatc aagaaattta tcggacaata ctttgcggta ttaaatggtg cagatgcctt
     2041 ggtctttacc gcaggtatgg gtgagaatgc tcccttgatg cgccaagatg tcgtcaatgg
     2101 cttgtcatgg tttggtatgg aaattgatcc agagaaaaat gtgtttggtt atcgtggtga
     2161 tatttcaaca gcagcttcaa aggtgaaggt gcttgtcatc tcaactgatg aagagctgtg
     2221 tattgcgcgt gacgttgaac gcttgaaaca gactatatca taatctgata atatactctt
     2281 agctcagctg atcagtttta aagagtccaa aaaatacttt taattggtac cgacctccaa
     2341 aagttagact taaaggttta acgattggag gtcggtatta ttatatagcc aaatattctc
     2401 aagacaaaga cagccaaaaa atgagacggt cgtaaccgtc tcaaaaaagt ttaatttaat
     2461 taaaaacatt cat
//
LOCUS       DARYXW010000130         2380 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.131, whole genome shotgun sequence.
ACCESSION   DARYXW010000130 DARYXW010000000
VERSION     DARYXW010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2380)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2380)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2380
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.131"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(<1..1031)
                     /locus_tag="TV191_001833"
     CDS             complement(<1..1031)
                     /locus_tag="TV191_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1508309.1"
                     /translation="MASLIPFEFKKLLRRQSVFGAIVVVLLAVGGLFYQHFFNGQISG
                     SSADQVHGRAAVAINQQIAEKHTGYLSDDLISRILNDYAKNQSDLKKKGVYSVVSHYA
                     ISHLVPKSTDKLIAINSTDKSLTFDNVHLKSREELGSALPLKELKLGNFAPWNQLFDV
                     TNSTYLLVVMLCLYITAPLFSGESSKKMNSILLTTVFGRGKLTLAKLAVSIAVSTLVF
                     AIASGLVFAVFATYFGFSGWDTSLQLNLYWIDPVINIMAFPEKMTLGIAFVYLLVFQY
                     IGLIFMTGIHALVSSLTKSPLTTFGISALIVYAPVFLMGIFPEGLMNKLLTFVSVQTF
                     GTQELLLKLA"
     gene            complement(1037..1891)
                     /locus_tag="TV191_001834"
     CDS             complement(1037..1891)
                     /locus_tag="TV191_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000926579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1508310.1"
                     /translation="MLLILDNISKSYGSKKVLSRISAQFTPGLYGLLGANGTGKTTLL
                     NIISQFTVPDSGEISLNHQQQPKNFYQNIGFLPQQFNYYQQFSGLEFLLYMAALKNVK
                     RKKALVEADRLLKLVGLYDVRKKKIASYSGGMKQRLGIAQALINDPLLLILDEPTVGL
                     DPKERVKFRNIISDLSEQKIIILSTHIVSDVEAVAKEVILLKHGQFIEKGSVDQLVQT
                     MIGKVWEIPVATESAPAFLTDYAVVNEKIVKNNRILRVVSDESPCYQANPVSPTLEDL
                     YIYHFRKE"
     gene            complement(1958..2158)
                     /locus_tag="TV191_001835"
     CDS             complement(1958..2158)
                     /locus_tag="TV191_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="HEL1508311.1"
                     /translation="MNTKTIEQFSTMTADMLAGVEGGWGYRWRCTDGYTSAWHLLRDT
                     AQENADNHMILYPGTVCRVYNA"
BASE COUNT          797 a          488 c          375 g          720 t
ORIGIN      
        1 gccaatttta ataataattc ttgtgtacca aaggtttgta cggatacaaa tgttaacagt
       61 ttgttcatca aaccttctgg aaaaattccc attagaaaga ccggtgcata tacaataaga
      121 gcagatatac caaaagtggt tagaggagac ttagttagag atgaaactag tgcatgaatg
      181 cctgtcataa atatcaggcc aatatactga aacaccaata aatagacaaa cgcaatgcct
      241 aaggtcatct tttccgggaa agccataatg tttatcactg gatcaatcca atacaaattg
      301 agttgtaagc tagtgtccca gccgctaaaa ccaaaatagg tcgcaaagac agcaaagacc
      361 agaccactag caattgcaaa taccaaagta ctgacagcta tgctaactgc taatttagca
      421 agagtcaatt taccacgtcc aaaaacagtc gtcaataaga tagagttcat ctttttagat
      481 gattcccctg aaaataaagg agccgttata taaagacaaa gcataacaac aagaagataa
      541 gtactattgg ttacatcaaa caactgattc caaggagcaa aattacctaa cttcaactct
      601 ttcaaaggca gagcggaccc caactcttca cgtgatttga gatgaacatt gtcaaatgtc
      661 agagacttat cagtgctatt aatagcgata agcttatcag tagacttagg cactaaatga
      721 gagatagcat aatgtgatac cacactatat acacccttct tttttaggtc tgattgattt
      781 ttagcataat cattgaggat acgactaatc agatcgtcag ataaataacc tgtatgcttc
      841 tcagcaattt gttggttaat tgctacagct gcacgtccat gaacctgatc tgcagaagag
      901 ccactgatct gaccgttaaa aaaatgctgg taaaaaagac cacctacagc caataagacc
      961 actacaatcg caccaaatac cgactgtcgt cttaataatt ttttaaactc aaagggtatg
     1021 agagatgcca tagaattcac tcctttctaa aatgataaat gtagagatcc tctaatgttg
     1081 gtgacacagg atttgcctga taacaaggac tctcatcgct cacaacacgt aagatacgat
     1141 tattttttac aattttttca ttgacaacgg catagtcagt caaaaatgct ggtgcactct
     1201 ctgtagcaac aggaatctcc cataccttgc cgatcattgt ttgaactaac tgatcaacac
     1261 ttcctttttc tataaactga ccatgcttta gaaggattac ctcctttgca accgcttcta
     1321 catcagatac aatatgtgtt gataggataa taattttttg ctctgataaa tcactgataa
     1381 tatttctaaa ttttacacgt tcctttggat caagtccgac tgttggttca tctaaaatta
     1441 acagtaaagg atcgttgata agtgcctgag caatacccaa tcgctgcttc ataccgccag
     1501 aataagaagc aattttcttt tttctaacat cataaagacc taccagcttt aataaccgat
     1561 cagcttctac taaagccttt ttacgtttaa cattcttcaa agcagccata taaagaagga
     1621 attctaaacc ggaaaactgc tgataataat taaactgttg aggtaaaaag ccaatattct
     1681 ggtaaaagtt ttttggttgt tgttgatgat ttaaactaat ttctccacta tcaggaactg
     1741 taaactgact aatgatgttt aataaagtcg ttttaccggt cccatttgct cccaataacc
     1801 catacaagcc tggtgtaaat tgtgcagaaa tacgactcaa caccttttta cttccataag
     1861 atttagaaat attatctagt attaacaaca ttgtcattcc tcctaagtaa aaacccaggg
     1921 aacagcacca cttcgctgct ccccagatga ttaaccatta agcattatat actcgacaaa
     1981 cggtaccagg ataaagaatc atgtggttat cagcattttc ttgtgctgta tctcttaata
     2041 gatgccatgc acttgtataa ccatcagtgc atctccacct ataaccccaa ccaccttcaa
     2101 cgcctgcaag catatcagca gtcattgtac taaattgttc aattgttttt gtattcatat
     2161 cgaatacctc cttataatga ttttatctag ctacagtctc gacaaactta gtgtagcgct
     2221 ttttaaagca acgacactca aaaatcttga atggttctta ttttgtcgtg aatggtcaat
     2281 ttttcttctg aaattaccag ttaagatcat atggatacct ttcacgagct atatcttttt
     2341 ctctcttttc ttatgatata attgattttt gcatgtacat
//
LOCUS       DARYXW010000131         2377 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.132, whole genome shotgun sequence.
ACCESSION   DARYXW010000131 DARYXW010000000
VERSION     DARYXW010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2377)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2377)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2377
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.132"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            104..313
                     /locus_tag="TV191_001836"
     CDS             104..313
                     /locus_tag="TV191_001836"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508312.1"
                     /translation="MTQVRVYLWLSCDDGDNIESNSMTSRKPLAKEDIKKVIVACLSF
                     SEVGYRLKEKGLGIRVSFWLLKSVI"
     gene            458..934
                     /locus_tag="TV191_001837"
     CDS             458..934
                     /locus_tag="TV191_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL1508313.1"
                     /translation="MTQDYISYIRSKVGHDNIILTFAGGILANAEGKVLLQLRADKKT
                     WAIPGGAMELGESSAETCRREFYEETGITVEPLRLLNVYTNFEETYPNGDKVQTVVML
                     YEVIAKADKAITDYQNDETLRLGYFSREEIAELSSISDKHRLMLAEYFAGEFQMGH"
     gene            complement(1097..2299)
                     /locus_tag="TV191_001838"
     CDS             complement(1097..2299)
                     /locus_tag="TV191_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEL1508314.1"
                     /translation="MKTDKQQELYAKILDTIYAQRPISRIDISKLTHITPATVGAITK
                     ELLAQGWIHEIGELTDHSVGRKKILLDASANAFYFAGVELSEKHFYLVITDNLGTIYA
                     KHNQQIDPSISSYYKADYISELIQAFLKQHKHYDVQAIGIALPGHYDHSTSSSTHINT
                     NNPIWQQVDLTAIAKSFPIPVVFSNNAHCMIIAKRLYERQAHNHNFIFFHVGRGMHCS
                     YMYKGVIYSRHNAVVGEIGHTIVNPTGELCECGKKGCLQTYASNAWLLKKAKLLHQYA
                     PNSHLRSLVDKACELKLDHLLIAYELGDVGVTTLIHTAIDYLVLSLSNLSLLIDTEQI
                     YLHGRFISHPLISSKILQALQNDIKLLSNQKKPEIIVMPFSVYNAAVGATGLCIDELY
                     LNYKNKYD"
BASE COUNT          689 a          412 c          582 g          694 t
ORIGIN      
        1 ttataaaggg tattttattt aaagattttg aaggaaaaaa acacctatag gtacaatcaa
       61 tcaaaaaaac agtaggtacc tactactgat tgaggagaag gcaatgacac aagtacgtgt
      121 ttatttgtgg ttatcatgtg atgatgggga taatattgaa agtaattcaa tgaccagtcg
      181 caaaccattg gccaaagaag acattaaaaa agttatcgta gcttgtctga gtttttctga
      241 ggttggttat agattgaaag aaaagggact tggcattcga gtctctttct ggcttttaaa
      301 aagtgtgata taatcaggtt gaaaaattag ggctatatgc tttgccagcc tatcaaggac
      361 aagagacaaa gcctgcattg cttattggtt ggcaaaaaag cagcaattgc gccagctgac
      421 tggctttaat cttatgatgg caatgaaggg agttacgatg acacaggact atatttccta
      481 tattcgctca aaggtggggc atgataacat tattctgact tttgctggtg gtattttggc
      541 caatgccgaa ggtaaggtgc ttttgcagct acgtgcagat aagaaaacct gggcaattcc
      601 gggaggtgcc atggagctgg gtgagtcttc tgctgaaacc tgcaggcgtg aattttatga
      661 ggagacgggg attacagtag agcctttacg gttgttgaat gtttatacca attttgaaga
      721 gacctatcca aatggtgata aggttcagac cgttgtgatg ctttatgagg ttatagccaa
      781 ggcagataag gctatcactg attatcaaaa tgatgaaacc ttaaggctcg gttatttttc
      841 tagagaagag attgcagagc tgtcttcaat ctcagacaag catagactga tgctggcaga
      901 gtattttgct ggtgagtttc aaatggggca ttaggataga acagagagaa ccaagtgcct
      961 ctcttttttt atggttatca tttgtctcgc acctgcggag cgagatggac tgaaagtcgc
     1021 ataatgcaaa agcccacttg agaaatagct tctcaaatgg gctttaaagc tttagctgat
     1081 attggtgtgg gggttatcaa tcatatttgt ttttataatt gaggtaaagc tcatctatac
     1141 ataagcctgt agctcccaca gcggcattat agacagaaaa aggcatgaca atgatttctg
     1201 gctttttttg attgctaaga agcttaatgt cattttgcag ggcttgcaga attttggagg
     1261 atataagagg atggctgata aatctgccat ggagatagat ttgctcggta tcaatcagta
     1321 aggagaggtt agacagggat aaaacaaggt aatcaatagc tgtgtgaatg agcgtggtca
     1381 ccccgacatc accaagctca taggcaatca agagatggtc tagcttgagc tcacaggcct
     1441 tatcgacaag gcttcttaga tgagaattgg gggcatactg atgtagcagt tttgcttttt
     1501 tgagcaacca ggcattgctg gcataggtct gtaaacagcc ttttttgcca cattcacaaa
     1561 gctctccagt ggggttgaca atggtatgtc cgatttcccc aacaacagca ttgtgacggc
     1621 tataaatgac ccccttatac atataggagc agtgcatgcc tcgtccgaca tgaaagaaaa
     1681 taaaattgtg attatgtgcc tgacgctcgt ataagcgctt ggcaataatc atacagtgag
     1741 cattgttgct aaagaccact ggaataggga aggacttcgc aattgcggtt aaatcgacct
     1801 gctgccagat gggattgttg gtgttaatat gcgttgagct ggaggtggaa tgatcgtaat
     1861 gcccaggcag tgctattcct atggcttgta catcatagtg cttgtgctgc ttgaggaagg
     1921 cttgaatcag ctcagagata tagtctgctt tgtagtagga ggaaatgctt gggtcgatct
     1981 gttggttgtg cttggcatag atggtgccca ggttatctgt aatgaccaaa tagaaatgct
     2041 tttcggacaa ttcgacacca gcaaaataaa aggcgttagc cgaagcatca agtaatattt
     2101 ttttgcggcc aacggagtgg tccgtcagct ctccgatttc gtgtatccac ccctgtgcta
     2161 gcagctcttt agtgatagcc cctactgtag caggtgtgat gtgcgttagc tttgaaatat
     2221 caatgcgtga aataggccgt tgggcataaa tggtatctaa aatttttgcg taaagctctt
     2281 gttgtttatc cgtcttcata gtaacctcta ttatcgtacc tctatcatac caaaaaagaa
     2341 ttaaaaatcc tgcctgaaaa cgttgacaaa tattggt
//
LOCUS       DARYXW010000132         2351 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.133, whole genome shotgun sequence.
ACCESSION   DARYXW010000132 DARYXW010000000
VERSION     DARYXW010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2351
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.133"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            <1..185
                     /locus_tag="TV191_001839"
     CDS             <1..185
                     /locus_tag="TV191_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009530021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1508315.1"
                     /translation="MENIEVLKEYRSIDISIDDFLEMMRRYKKEEKQEKMKLQEMRNT
                     ENHNNMEENHENQMEE"
     gene            190..1626
                     /locus_tag="TV191_001840"
     CDS             190..1626
                     /locus_tag="TV191_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HEL1508316.1"
                     /translation="MAITLSGVIFLILALLGTMLFNHQIVFAQGSLIPTLISPTEVLA
                     QTKVEVKIKYIFKDESVYKEEIIEVETGQVLDSGDLPMLEDNMKFIDEFLFYKVKGDG
                     TDEIIRKVEKITVKDKEIQTEEEKPKQDESTETEDKKTEDKGTQTELSKDDISKMEKE
                     AKELQDKLDKLNGEIRDKDKLSDKQKEKIKDLEAEIESLKEKMKKDKGNKDLSEDMKK
                     EIDKLTEKVKELEKKPTETNKAPVTSQSVTPISPISGIKTSSGISSQTPQSSGKGSSD
                     AVSSGNTTKDTGKTESKEKEKEVRYPNKLTPKAPANNSSQDSSMDGASSNVNTNKGVA
                     SAPSKARGTVTENKDNANNDYPIHHGDSSDNKEADKYSADARQFITFQTKSGKTFHLI
                     INHDEQSENVMLLTEVSEDDLLNMVEKKENPQEEIKKMEETVPESEVKKEEPKKEEGK
                     GSGSYIFLGIIVLAVVGAGYYFKIYKKK"
     gene            1879..>2351
                     /locus_tag="TV191_001841"
     CDS             1879..>2351
                     /locus_tag="TV191_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005956659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HEL1508317.1"
                     /translation="MNYENKIEKYLKQSGGIITTAYCKENNIPTIYLSRLLKDGRLSK
                     VRKGIYITKDGDYDEYYFFQHQYKKAIFSYETALYLLGQTDKIPWSIDVTVYNGYKFN
                     EKPNGFNVHYVKKSIYDLGVTQKPTMFGNKVKVYSYERTLCDFIAHKEEMDIEVYV"
BASE COUNT          992 a          293 c          503 g          563 t
ORIGIN      
        1 agatggaaaa tattgaggtt ttaaaggaat accgaagtat tgacatttct attgacgatt
       61 ttttagaaat gatgagacgt tataaaaaag aggaaaaaca agaaaaaatg aagttacagg
      121 aaatgagaaa tacagaaaat cataataata tggaggaaaa tcatgaaaat caaatggaag
      181 aataaaaaaa tggcgataac attgtccgga gtaatctttt tgatacttgc tttacttgga
      241 acaatgcttt tcaatcacca gattgttttt gcacaaggta gtttaatccc gacactgatt
      301 agtcccacag aagttttagc tcaaactaaa gtggaggtta agataaaata tatatttaag
      361 gatgagagtg tatataagga agaaataatt gaagtagaaa ccgggcaagt tcttgacagt
      421 ggggacctac caatgttaga ggataatatg aaatttattg acgaattttt gttctataaa
      481 gtaaagggag acggtacaga tgagattatc cgtaaagtag aaaaaattac agttaaggat
      541 aaagaaattc agacagaaga ggaaaagcca aaacaggacg aaagcactga gacggaagat
      601 aaaaaaacag aagataaggg aacacagaca gagctttcta aagatgatat ttccaaaatg
      661 gaaaaagagg caaaagagct tcaggataaa cttgataaat taaatggtga aatcagggat
      721 aaagacaaac taagcgataa acagaaagaa aaaatcaaag accttgaagc tgagattgaa
      781 agtctgaaag aaaaaatgaa gaaagataag ggaaataaag acttatcaga agatatgaaa
      841 aaggaaatag ataagctgac ggaaaaggtg aaagagcttg agaaaaagcc aactgaaaca
      901 aacaaagctc ctgtaacatc acagtctgtt acaccgatta gtcctatttc agggattaag
      961 acaagctcag gtatttcttc tcaaacacca cagagttccg gtaaaggttc atctgatgca
     1021 gtaagctccg gcaatactac aaaagataca ggtaaaactg aatcaaagga gaaagaaaag
     1081 gaagttcgct atcccaataa gctgacaccg aaagctcctg ctaataacag tagtcaggat
     1141 tcatcaatgg acggtgcaag tagcaatgta aataccaata agggtgtggc ttcagctccg
     1201 tcaaaggcaa gaggaactgt tacagaaaat aaagataatg cgaataatga ttatccaatt
     1261 catcatgggg atagcagcga taacaaagaa gcagataagt attcagcaga tgcaagacaa
     1321 tttattactt tccagacaaa atccggaaag acatttcatt taatcatcaa tcacgatgag
     1381 caaagtgaaa atgtaatgct tttgactgaa gtatctgaag atgatcttct gaatatggta
     1441 gagaagaagg aaaacccgca agaagaaatc aaaaaaatgg aagaaacggt accggaaagc
     1501 gaagtaaaaa aagaagagcc gaaaaaggaa gaaggtaaag gtagcggctc atatattttt
     1561 ttaggaatca tcgttcttgc agtagttgga gcaggatatt actttaaaat ctacaagaaa
     1621 aagtaggaag atgatgatta tgatgaagat gaggaagaat atgatgaatt tgaagatgag
     1681 tatgaaaaag aggacgatac agaagatttg gaagaaacag tagaagaaca gcataacata
     1741 gatgatatgg caatcgactc ttatgatgaa gaagatgagg aataaagtta taaaaagaga
     1801 aatgtaaacc ctgatgttgc gtttacactt aaaaaatggt ataatgcaag tgtaaacgca
     1861 acaaaggggg tggatgggat gaattatgaa aataaaattg aaaaatattt gaagcaatca
     1921 ggtggaatta ttacaacagc atactgtaag gaaaataata taccgacgat atatctcagt
     1981 cgactattga aagatgggag attgtcaaaa gtaagaaaag gaatttatat aacgaaagat
     2041 ggggattacg atgagtatta tttctttcaa catcagtata aaaaggcgat attttcttat
     2101 gaaacagcac tttacctgct tggacaaaca gataaaattc cttggagtat cgatgtaacc
     2161 gtttataacg gatataaatt taatgaaaaa ccgaacggtt tcaatgttca ttatgtaaaa
     2221 aaatcaattt atgacttagg ggtaacccaa aaacctacaa tgtttggaaa taaagttaag
     2281 gtatattcat atgagaggac actctgtgat tttattgctc ataaagaaga aatggatata
     2341 gaggtttatg t
//
LOCUS       DARYXW010000133         2350 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.134, whole genome shotgun sequence.
ACCESSION   DARYXW010000133 DARYXW010000000
VERSION     DARYXW010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2350
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.134"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(40..588)
                     /gene="raiA"
                     /locus_tag="TV191_001842"
     CDS             complement(40..588)
                     /gene="raiA"
                     /locus_tag="TV191_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEL1508318.1"
                     /translation="MIKFSIRGENIEVTEAIRDYVESKLTKIEKYFVEEQEIDARVNL
                     KVYREKTAKVEVTIPLGSVTLRAEDVSQDMYGSIDLVVDKIERQIRKNKTKIAKKHRE
                     KMSTSQVFTSEFEAEKAEETPEIKVVRTKNVTLKPMDVEEARLQMELLGHDFFIYTDA
                     EDGATNVLYRREDGDLGLIEAK"
     gene            complement(664..1290)
                     /locus_tag="TV191_001843"
     CDS             complement(664..1290)
                     /locus_tag="TV191_001843"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEL1508319.1"
                     /translation="MSITAILLLSPNKDLMCDACQRHFCRITQPTCSNCYQYRHEGAC
                     QDCIAWKRQGYQVDHQSLYQYNTAMKDYFSRYKFQGDYVLRSLFAQELAKHIKKYYKA
                     YTLVPVPVSKQRYDERGFNQVTAILEYANLAYLDLFERIDDTRQSSKTKKERLQLNNR
                     YRLKKGAALPPKILLIDDIYTTGSTIMSLRQELVRHGCQDIKSLSIAR"
     gene            complement(1473..1658)
                     /locus_tag="TV191_001844"
     CDS             complement(1473..1658)
                     /locus_tag="TV191_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEL1508320.1"
                     /translation="MLTYEEFKQAIDHGYITGDVVMIVRKNGQIFDYVLPGEEVQPWE
                     VVTVEAVADILNELQII"
     gene            complement(1780..>2350)
                     /gene="spel"
                     /locus_tag="TV191_001845"
     CDS             complement(1780..>2350)
                     /gene="spel"
                     /locus_tag="TV191_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeL"
                     /protein_id="HEL1508321.1"
                     /translation="KPVTGKRGTQVIIDAQHKTKVWEFDDYNFIISSNLYPSVEGKFN
                     VGDNVDVFGLALSAEVFSKDQIHSINGGLVKVNERKGAGKTIYMNVFIDGHKKDETSK
                     YKITFEKSPVTFQEVDVRLRKSFMLNDEIKLYQYGSKVLSGNWEFHGSGENEEGADLF
                     KYPDYRYNNLIDIDKKSHIDVYLFTNKEN"
BASE COUNT          661 a          500 c          381 g          808 t
ORIGIN      
        1 gcaaaaaaac aagaggtgag atgcctcttg tttttcaaat tattttgctt cgataagtcc
       61 taagtcacca tcctcacgac gataaagaac atttgttgct ccgtcctcag catctgtata
      121 gatgaagaaa tcatgcccta gaagttccat ctgcaagcga gcttcctcaa cgtccattgg
      181 ctttagagtc acatttttcg tgcggaccac tttgatttct ggagtttctt cagctttttc
      241 tgcttcaaat tcactagtaa acacttgact agttgacatt ttttcacgat gctttttggc
      301 aatttttgtt ttattttttc taatttgacg ttcgatttta tcaacgacta aatcaataga
      361 accatacata tcctgtgaaa cgtcttctgc acgaagtgtc actgaaccaa gcggaatagt
      421 gacttcaacc tttgcagtct tttcacgata aacctttaaa ttaacacgcg catctatttc
      481 ttgctcttca acaaaatatt tttcaatctt agtaagcttt gattctacat aatcgcgaat
      541 agcctctgtc acttcgatgt tttctccacg aatactgaat ttaatcataa gagtacctct
      601 ttcttgcgtt taaaacgctt tctttagttc tactatagcc gttttcatga aaatttgcaa
      661 gttttatcgt gcaattgaga gacttttgat gtcctgacag ccatgcctga caagctcctg
      721 ccttagactc attatggtgc taccggttgt atagatatcg tcaattaata agattttcgg
      781 tggaagagct gctccctttt tgagtcgata gcggttattt agctgcaggc gttctttttt
      841 cgttttgctt gattgtctag tatcgtcgat tcgctcaaat aggtcaagat aggctaggtt
      901 ggcatattct aaaatagctg ttacttgatt aaagcccctt tcatcatacc tttgcttgct
      961 aacaggcaca ggaaccaaag tataggcttt ataatacttt ttaatgtgct tagctagctc
     1021 ctgcgcaaaa agactgcgta aaacataatc tccttgaaat ttgtaacggc tgaaataatc
     1081 cttcattgcg gtgttgtatt ggtaaaggct ctgatgatca acctgatagc cttgcctttt
     1141 ccaggcaata caatcctggc aggcgccctc atgacgatac tggtagcaat tagagcaggt
     1201 tggctgagta atcctacaaa aatgacgctg acaggcatca cacataagat ccttattagg
     1261 acttaacaac agaattgctg tgatagacaa gctatcttta ctatttattg tggcagagta
     1321 gacagttcat tttgataccc tttttgattc atgtccttta tctcccgcac tgccttgagc
     1381 atagcctggc taataccatc atgaaaaaat agcacctgtc cttcaggtct ttccaaagag
     1441 cgcccaacgc gacctgaaat ttgaattagc ggtcaaataa tttgtaattc gtttaaaata
     1501 tcagcaactg cctcgactgt caccacttcc caaggctgca cttcctcccc tggcaacaca
     1561 taatcaaata tctgtccgtt tttacgcacg atcatgacca cgtctcctgt gatatatcca
     1621 tgatcaatag cttgcttaaa ttcctcgtat gttagcataa attacctcct tatcttatta
     1681 ttcgtaaaaa tctggtattg gtatattgga cacatttata tgtaccgaac aaaaaaacgc
     1741 cctcaattaa gagggtattc cttggtttct tgatactaac taattttctt tgtttgtgaa
     1801 tagatagaca tcaatatgac tctttttgtc tatatctatc aaattattat atctataatc
     1861 tgggtattta aataagtcag caccttcctc gttctcgcct gagccgtgaa attcccagtt
     1921 tccagataga actttggaac catactgata aagttttatt tcatcgttca gcataaatga
     1981 ttttctcaat ctaacatcaa cctcctggaa ggtaacggga gatttttcaa aagttatttt
     2041 atatttcgag gtctcatctt tcttatgccc atcaataaaa acgttcatgt aaatcgtttt
     2101 tccagctcct tttctctcat taactttaac gagaccacca ttgattgaat gtatttgatc
     2161 ttttgaaaat acttcagccg ataatgcaag accaaaaaca tcgacattat ctccaacatt
     2221 aaatttacct tctacagatg ggtataggtt acttgatatt ataaaattat aatcatcaaa
     2281 ttcccatact ttagttttat gctgagcatc tataataact tgcgtccctc tttttccagt
     2341 aacgggttta
//
LOCUS       DARYXW010000134         2299 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.135, whole genome shotgun sequence.
ACCESSION   DARYXW010000134 DARYXW010000000
VERSION     DARYXW010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2299
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.135"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            <1..409
                     /locus_tag="TV191_001846"
     CDS             <1..409
                     /locus_tag="TV191_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="SPASM domain-containing protein"
                     /protein_id="HEL1508322.1"
                     /translation="AAHYNKLIEKFSCLGVQFLTSPFCHPWSLAIKHGIEYHSPLYCP
                     AQKTEFEIDMYGDVYPCPFLHDKIHLMGNLISDDFETIWYSGVEQLNRRAWSSNDSCK
                     NCKLFNDCGGGCYAMAFVSQLEYDKRCILHANQ"
     gene            396..656
                     /locus_tag="TV191_001847"
     CDS             396..656
                     /locus_tag="TV191_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEL1508323.1"
                     /translation="MQISKNWFIRFEPNFQTTQNTILFNKVSGELFEVTEVYYDCINS
                     LRIGVDFQALLMEKYAVNAGDVIDVEDTILKNLISLGVILNE"
     gene            649..1548
                     /locus_tag="TV191_001848"
     CDS             649..1548
                     /locus_tag="TV191_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002900052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1508324.1"
                     /translation="MSDITIRHVKKSFHHQVVLDVPSFDVKRGEIVAIVGANGAGKST
                     LIKMISGLMLQDTGSVLVYHHKNTSAAIHRDVKFVLESGRGYYEYLTANQNIDYFLHL
                     NNLSRSQVKEELAELCQKLAFNPYTDRLVSELSQGTRQKLSLIIALLCQPKVLCLDEP
                     TNGLDVVAKKQFATLLLELSQKKQTIILMTTHDIFFVKELSARICVMSKGKIKKQGSF
                     SEIFGENNTWMKYRIGIPKFEKAIFDQLFPFLAYQVEDERLVVEVTDSQTKHHIFEHF
                     EIIFFEEVEKSIEELLYEVITDD"
     gene            1538..2278
                     /locus_tag="TV191_001849"
     CDS             1538..2278
                     /locus_tag="TV191_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002909393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1508325.1"
                     /translation="MMIKEIQRELKRQLQEMMQFKFNLFFANFGILIMVSSYLHYFED
                     TQSQFLLLCLLFTWYFTSHSLTHPIFFIEDDLYDRTLISVIQSSKSVFHVLMLKIIVQ
                     LLVDLVKAIPIVIMLSLLNNIDFPESSLRVMGSFVACFLTVISTYGLGFCLSSLCFVF
                     NRTSSVTALISYFMLYFTGILTPLDGSLGLIGKMFPYYALRNAIMSPSYQSVCWIVAY
                     GMIYWSVGTLLFSRALTMAKKRGSLFHV"
BASE COUNT          703 a          335 c          463 g          798 t
ORIGIN      
        1 tgctgcacat tataataaat tgatagagaa atttagttgt ttaggtgttc aatttttaac
       61 atcacctttt tgtcacccat ggtctcttgc aataaagcat ggaattgaat atcattcccc
      121 actttactgt ccagctcaaa aaacggaatt tgagattgat atgtatggag atgtctatcc
      181 ttgtccattc ttacacgata aaattcactt aatgggaaat ttaatttctg atgattttga
      241 aactatttgg tactctggag tagaacagtt aaatagaagg gcttggtcaa gtaatgatag
      301 ttgtaaaaat tgtaaattat ttaatgattg cggtggaggg tgctatgcca tggcatttgt
      361 ttcacagcta gaatatgata agaggtgtat attacatgca aatcagtaaa aattggttta
      421 ttagatttga acctaatttt caaacgacac aaaatacgat attatttaat aaagtaagcg
      481 gagagctgtt tgaggtaaca gaagtttact atgattgtat caattctctg agaattggtg
      541 tcgattttca agctcttctg atggaaaagt atgctgtcaa cgcaggggac gtgattgacg
      601 tagaagatac gattttaaaa aatctaatat cgctaggagt aattcttaat gagtgacatc
      661 actatacgcc atgtcaagaa aagctttcat catcaggtag tcttagatgt gcctagtttt
      721 gatgtaaagc gtggagaaat tgttgctatc gttggtgcaa atggtgcagg taaatcaact
      781 ttgatcaaaa tgatctctgg tttaatgctg caagacacag gatctgtttt ggtttatcat
      841 cataaaaata cttcagcagc tattcatcgt gatgtgaaat ttgtcttaga aagtggtagg
      901 ggctattacg agtatctgac tgcaaatcaa aatattgatt actttttaca tttgaataac
      961 ctgtcacgta gccaagtcaa agaagaattg gcagagttgt gccaaaaatt ggcttttaat
     1021 ccctatactg atcggttggt ttctgaatta tcccaaggca caagacaaaa attgtctttg
     1081 attattgctc ttctttgtca gcccaaggtt ctgtgcttag atgagccaac aaatggtcta
     1141 gatgtggttg caaaaaagca atttgcaacc ttgttgcttg agcttagtca aaaaaagcaa
     1201 acgattatcc tgatgacgac tcatgatatc ttttttgtaa aagagctatc agcaagaatt
     1261 tgtgtcatga gtaaagggaa gatcaaaaaa caggggagtt tttcagaaat tttcggagaa
     1321 aacaatacgt ggatgaaata tagaatcggt atccctaagt ttgagaaggc tatttttgat
     1381 cagttatttc ctttcttagc ttatcaggta gaagatgaga gattagtcgt cgaagtgaca
     1441 gatagtcaga caaaacatca tatctttgag cattttgaga ttatattttt tgaagaagtt
     1501 gaaaaaagca tcgaagagct attatatgag gttattactg atgattaaag aaatacaaag
     1561 ggagttgaaa agacaattgc aggagatgat gcaattcaaa ttcaatttat tttttgcaaa
     1621 ctttggtatt ttgatcatgg tgtcatctta tcttcactat tttgaagata cgcagagtca
     1681 gttcttgtta ttatgtctat tattcacttg gtattttacg agtcatagcc tcacacatcc
     1741 aatctttttt attgaagatg acctttatga tagaacgttg atcagtgtta ttcaaagcag
     1801 caagagtgtt tttcatgtcc tcatgcttaa aattattgtt caactattgg tggatttagt
     1861 taaggcaata cctattgtta ttatgttatc actccttaat aatattgact ttccagaaag
     1921 tagcttgagg gtgatgggaa gctttgttgc ctgttttttg acagtcatta gtacatacgg
     1981 tcttggcttt tgcttatcca gtctctgttt tgtgtttaat cgtacctcca gtgttactgc
     2041 gttaatttct tatttcatgc tatactttac cggcatacta acgccattag atggctcact
     2101 tggtcttatt ggaaaaatgt tcccttatta tgctttgaga aatgctatta tgtctccttc
     2161 atatcagagc gtatgttgga ttgtggctta cggtatgata tattggtcgg tcggtacgtt
     2221 attgttttct agggcattga caatggctaa aaaaagaggg agtctttttc atgtttagtg
     2281 aaatgaaacg atatatgac
//
LOCUS       DARYXW010000135         2216 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.136, whole genome shotgun sequence.
ACCESSION   DARYXW010000135 DARYXW010000000
VERSION     DARYXW010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2216)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2216)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2216
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.136"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(97..1722)
                     /gene="groL"
                     /locus_tag="TV191_001850"
     CDS             complement(97..1722)
                     /gene="groL"
                     /locus_tag="TV191_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880885.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEL1508326.1"
                     /translation="MAKDIKFSADARESMVRGVDILADTVKVTLGPKGRNVVLEKAFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPIGIRRGIEAATTTAVEALKAVAQPVSGKEAIAQVASVSSRSEKVGDYI
                     SEAMERVGNDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDNEKMVADLENPFI
                     LITDKKISNIQDILPLLEEVLKTSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAVLTGGTVITEDLGLELKDATMAALGQAAKVTVDKDNTVIVEGA
                     GSSEAISNRVSLIKSQLETTTSEFDREKLQERLAKLAGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALINVMDKVAALELDGDAATGRNIVLRALEEPVRQ
                     IAYNAGYEGSVIIDKLKNSAAGIGFNAATGEWVDMIATGIIDPVKVTRSALQNAASVA
                     GLILTTEAVVATKPEPAAPAMPQGMDPGMMGGF"
     gene            complement(1790..2077)
                     /gene="groES"
                     /locus_tag="TV191_001851"
     CDS             complement(1790..2077)
                     /gene="groES"
                     /locus_tag="TV191_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEL1508327.1"
                     /translation="MLKPLGDRVVLKFEAEKEQTVGGFVLAASHKEATKVGTVVAVSE
                     TGIRTITGDIVPPSVAVGDKVLVEYGSGLEVKDGDQELVICREADILAVLA"
BASE COUNT          626 a          557 c          389 g          644 t
ORIGIN      
        1 agggataatc atatcacctt aacgtcaggg gagtctttat aagttatttt tatatcctat
       61 gacagacaca ctagtctatc ctaacaggcc ttcttgttag aagccaccca tcatgcctgg
      121 atccattcct tgcggcattg ctggtgcagc aggctctggc ttagtggcaa caacagcttc
      181 ggtggtcagg ataagacctg caacagaggc tgcattttga agtgctgaac gtgttacctt
      241 gactggatca atgatacctg tagcaatcat atcaacccat tcaccagttg ctgcattaaa
      301 accaatacca gcagcactat ttttcagctt atcaataatc actgaacctt catagccagc
      361 gttgtaagca atttgacgca caggctcttc aagcgcacga agcacgatat tgcgaccagt
      421 tgctgcatca ccatcaagct caagggctgc aaccttatcc atgacattga taagagcagt
      481 accaccacct gcaacgatgc cttcttcaac cgcagcgcgt gttgcattta gcgcatcctc
      541 aatacgaagc ttcatttctt ttagctcggt ttcagtagct gcacccacct tgataactgc
      601 aacaccacct gctaattttg ctaagcgctc ttgtaatttt tcacgatcaa attcagatgt
      661 ggttgtttct aattgtgatt tgatcaggct aacgcggttt gaaatagctt ctgagctgcc
      721 tgcaccttct acaatcactg tattatcctt gtcaacagtt actttagccg cttgtccgag
      781 ggcagccatt gtagcatcct tcaattcaag accaagatcc tcagtgatga ctgtaccacc
      841 agttaagaca gcaatgtctt caagcatcgc tttacgacga tctccaaagc caggcgcttt
      901 aaccgctaca acattgaagg taccacgaat tttattaagc actagggtcg gaagggcttc
      961 gccatcaaca tcatcagcaa tgatcaacaa tggacggcta gtcttaagca cctcctcaag
     1021 caatggaaga atgtcttgga tattagaaat tttcttatca gtaatcagga taaatgggtt
     1081 ttcaagatca gcaaccattt tttcattgtc agtgaccatg tattgtgaca aatagccgcg
     1141 gtcaaactgc attccctcaa caacctcaag ctctgtttcc ataccacgtg attcctcaat
     1201 agtaatcaca ccatcatttc ccacgcgctc catagcttca gaaatatagt caccaacctt
     1261 ttcagaacgt gatgacaccg aagctacttg agcaatagct tcttttccag atactggttg
     1321 agcaacagcc tttaaggcct cgacagctgt cgttgtcgct gcttcaatcc cacgacgaat
     1381 accaattggg ttagcacctg ctgttacatt tttaagccct tcacgcacaa tcgcttgggt
     1441 caaaacagta gctgttgttg tcccgtcacc agcaatatca tttgtttttg aagctacctc
     1501 tgatacaagc ttagccccca tattttcaaa atgatcttct aattcaatct ctttggcaat
     1561 cgttacacca tcatttgtga tcaaaggaga accaaaggcc ttttcaagga ctacattacg
     1621 ccctttaggg ccaagggtta ccttaacggt atccgccaaa atatcaacac cacgtaccat
     1681 gctttcacga gcatctgctg aaaattttat atcttttgcc atgttatttc ctctattcct
     1741 atttgaatgt atatctgtta atcctacctg aaatgatagg gattcacaat taagctaaaa
     1801 ctgcaagaat gtcagcttca cgacagatga caagctcttg atcgccatct ttaacctcta
     1861 agcctgatcc atattcaacc aaaaccttgt cacctacagc cacacttggt ggaacaatgt
     1921 ctccagtaat agtacgaata cctgtctcac taacagctac aactgtccct actttagtgg
     1981 cttctttgtg actagcagca agaacaaagc caccgacggt ctgctctttt tctgcttcaa
     2041 attttaggac cacacgatct cctaacggtt ttaacatgaa tagtacctcc aataatgact
     2101 agattatcta ttttgttagc actcttgttt tatgagtgct aactttcttc tctattttat
     2161 cacttggtca aaaatagtca agaaaaaaag tctaggaaaa aagaaaagac ccagct
//
LOCUS       DARYXW010000136         2187 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.137, whole genome shotgun sequence.
ACCESSION   DARYXW010000136 DARYXW010000000
VERSION     DARYXW010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2187)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2187)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2187
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.137"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(169..1218)
                     /locus_tag="TV191_001852"
     CDS             complement(169..1218)
                     /locus_tag="TV191_001852"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515503.1"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="HEL1508328.1"
                     /translation="MKTIAYPNKPHSLSAGLLTAIAIFSLASSNITYADDYQRNATEA
                     YAKEVPHQITSVWTKGVTPLTPEQFRYNNEDVIHAPYLAHQGWYDITKAFDGKDNLLC
                     GAATAGNMLHWWFDQNKTEIEAYLSKHPEKQKIIFNNQELFDLKAAIDTKDSQTNSQL
                     FNYFRDKAFPNLSARQLGVMPDLVLDMFINGYYLNVFKTQSTDVNRPYQDKDKRGGIF
                     DAVFTRGDQTTLLTARHDLKNKGLNDISTIIKQELTEGRALALSHTYANVSISHVINL
                     WGADFNAEGNLEAIYVTDSDANASIGMKKYFVGINAHRHVAISAKKIEGENIGAQVLG
                     LFTLSSGKDIWQKLS"
     gene            complement(1742..2098)
                     /locus_tag="TV191_001853"
     CDS             complement(1742..2098)
                     /locus_tag="TV191_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508329.1"
                     /translation="MEDTYMTQACKKFMVSTMAALALAGVCLTASTHISKADDYVYGD
                     VEYLLTPKQEGYDDLVSFLESLGLNHFDATLYSDSMADQDYKKLLADFKGKTRSEVIS
                     AVLSELAKFYNDYSPF"
BASE COUNT          644 a          394 c          438 g          711 t
ORIGIN      
        1 atctagttta cttatcttag aaaagaacaa caggcacatt aatgtttaac aaaacaagag
       61 cttaaagagt tcatgacaag ctttaaccaa tgacagtgag ctaatagggc tattgttaga
      121 cgaaaaaaca gaccaataag cacttggtct gttcctaatg atgactggtt agctcagttt
      181 ctgccatatg tccttgccac tggaaagcgt aaataagcct aatacttgag cgccaatgtt
      241 ttctccttct attttcttgg cagaaatggc gacatgtcta tgagcattaa tgccgacaaa
      301 atattttttc ataccaatag acgcattagc atctgagtct gtgacataga tggcctcaag
      361 gtttccttca gcattaaaat cagctcccca caagttaatc acatggctaa tgctaacatt
      421 ggcgtaggta tgtgataaag caagggctct tccttcagtc agttcttgct tgataatggt
      481 gctgatgtca tttagtcctt tattttttaa atcatgacga gctgtcaaga gcgttgtctg
      541 atctcctctg gtgaaaacag catcgaaaat accacctcgt ttgtccttgt cctgataagg
      601 tcgattgaca tcagtagact gtgttttaaa cacatttaag tagtaaccat tgataaacat
      661 gtctagaaca agatcaggca taaccccgag ttgacgtgct gatagatttg gaaaggcttt
      721 atctctaaaa taattaaaaa gctgactatt ggtttgactg tccttggtat cgatagcagc
      781 tttcaaatca aatagctctt ggttgttaaa aatgattttt tgcttttcag ggtgtttact
      841 taaataggct tcaatctctg ttttattttg atcaaaccac caatgcagca tattacctgc
      901 cgttgctgcg ccacacaaga gattatcctt cccatcgaag gccttggtga tatcgtacca
      961 gccttgatga gcaagatatg gcgcatggat cacatcttcg ttattatatc gaaactgctc
     1021 gggtgttagt ggtgtaacac ctttggtcca tacagaagtg atctgatgtg gtacttcttt
     1081 ggcataagct tccgtagcat tcctttggta atcgtcagca taagtaatgt ttgaactcgc
     1141 caggctaaaa atagctatag cagttaagag accagctgat aaggagtgag gtttatttgg
     1201 ataagctatt gttttcatat aaccctttct tgttatggtg atattatcat taaataatgt
     1261 taatgacatt tatatattat cacaatattt tgttgagaca atgcttttga taagctttat
     1321 ttattagtaa atagtgatga gatagtagag atgctggcag actggatctc tataatggat
     1381 atttcagctt ggtttatgtt agcgttacct attttaccaa tgatgatacc gtttggtatt
     1441 gttggtgtca tgccttagac atgagctgtt attattgaga ccactaataa gagctagtgt
     1501 aggctttgat gttattggga ttcttgcaca atcttagcca agcttagtca gcaaatcagg
     1561 gcattagcta ggatagtaag gacaatggtg cagttattac ttgattagct aggcggacga
     1621 tttaggagat ggtctggtta ctaagcagat tgacaaagag aagcatagct ctatcaagtt
     1681 aaaaccgctc ggaaggttgt ctgagcagtt ttgatctatg ataacttatt gggttatttc
     1741 attaaaaagg ggaatagtcg ttataaaatt tagctaattc agatagaact gcagaaataa
     1801 cttcactacg agttttaccc ttaaagtcag ctagtagctt tttgtaatct tgatcagcca
     1861 tagagtccga ataaagagtg gcatcaaaat ggttaaggcc tagactctcc aagaatgaca
     1921 ccaaatcatc gtatccttct tgcttaggcg tcaaaagata ttccacgtca ccataaacat
     1981 agtcatcagc tttgctgatg tgggttgaag ctgttaggca gactcctgcc aaagctaggg
     2041 cagccattgt agaaaccata aatttcttac aagcttgtgt catataagtg tcctccattt
     2101 ccaacggttc ctttgtccgt cgttattttt gtgatatttt ccttatcaca atgttagttt
     2161 aactcaaaat ctgtcaaaag tcaaatg
//
LOCUS       DARYXW010000137         2156 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.138, whole genome shotgun sequence.
ACCESSION   DARYXW010000137 DARYXW010000000
VERSION     DARYXW010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2156
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.138"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            137..1564
                     /locus_tag="TV191_001854"
     CDS             137..1564
                     /locus_tag="TV191_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEL1508330.1"
                     /translation="MERLMRTQLKKLLAGTAAGTLLLFNLTCGMINAFAEQYYGWSDG
                     SSSYPSALYVTPVGDTTKKIAIPVYCFDYKFQEPLAWKEITQPSHLIVYDKYDGKNLM
                     AALVEKPNMVSYETKTKLQTLLKTKSNLITAILSRGYPNKSFFDKYKKLTDEDKRRVT
                     QCALWYHTDNISEQDLITKHLDGDSGEKSQALKELIGVVKNTSNELGEGLTFYTRYND
                     RYGPKYQNLIGSIIVPEEPQNDLEIGGGNVIDLNYQSGPMVEEGGHSGGKEEVEDTKK
                     PDVIIGGQGSVTETTEDTQKGMSGSTETQPEVEDTKQPQSDIILGGQGNVIDTTENTQ
                     EGMGGQSGDTTETEDTKQPQSDIILGGQGNVIDTTENTQEGMSGSNNGQTFEEDTRPK
                     LEFHFDNEVPNDDDAPKPEQPEQPEKPEQPRKPQQEQQSLPRPIEGNQSLPKTHEAKG
                     VLALVGVGILAMLGLGFWFRPYQKD"
     gene            1830..2099
                     /gene="rpsO"
                     /locus_tag="TV191_001855"
     CDS             1830..2099
                     /gene="rpsO"
                     /locus_tag="TV191_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEL1508331.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNNHIK
                     EHKKDHATYRGLMKKIGHRRNLLAYLRRTDVNRYRELIQSLGLRR"
BASE COUNT          746 a          377 c          482 g          551 t
ORIGIN      
        1 taatctaaaa aaattatatt gttctgattg ttcggtaatt aaagcaatag cgcttgtcga
       61 aaaactaatg ttctcttaat atcaggtagc catgccaagg gttttgtgtt aaagtatagg
      121 acgttcaaaa aatgaaatgg agagactaat gagaacacaa ttgaaaaaat tgctggcagg
      181 aacagcagca ggtaccctgc tgctgtttaa cctgacctgc ggaatgatta atgcttttgc
      241 agagcagtat tacgggtgga gtgacgggag tagcagctat ccgagtgctt tgtatgttac
      301 accggtagga gatactacga aaaagatagc tattcctgtt tattgctttg actataagtt
      361 tcaggagcca cttgcttgga aagaaataac tcaaccgtca cacttgattg tctatgataa
      421 gtatgatggc aaaaatttga tggcagcact ggttgaaaaa cctaatatgg taagctatga
      481 gactaaaact aaacttcaaa cacttttaaa gacaaagtca aatctaataa ctgcaatttt
      541 aagtagaggt tatccaaaca aaagtttttt tgataagtat aaaaaattaa ctgatgaaga
      601 taaaagacga gtgacacaat gtgctctttg gtatcatact gacaatattt cagaacaaga
      661 tcttatcaca aaacatttgg atggggattc aggtgaaaaa agtcaagcgc taaaggagtt
      721 aataggggtt gtaaaaaata cttctaatga gttaggagag ggattaacct tctatactcg
      781 ttataatgat agatatggtc ctaaatatca aaacctaata ggctcaatta ttgttcccga
      841 agagcctcag aatgatcttg aaattggtgg tggaaatgtt attgatttaa actaccaatc
      901 tggaccaatg gtagaagaag gtggtcattc aggtggcaag gaagaggtcg aggacactaa
      961 aaagcctgat gtgattattg gtggtcaggg aagcgttact gagactactg aggatactca
     1021 aaagggtatg agtggcagta ctgagactca gccagaggtt gaggatacta agcagccaca
     1081 atcagatatt atcctaggcg gacaaggcaa tgtgattgac acaactgaaa atacccaaga
     1141 gggcatgggt ggccaatcag gtgatactac agagactgag gataccaagc agccacaatc
     1201 agacattatc ctaggtggac agggcaatgt aattgacacc actgaaaata ctcaagaggg
     1261 tatgagtggt tccaacaatg gtcaaacatt tgaggaggac acacgtccta agctggaatt
     1321 ccattttgat aatgaagtgc ctaacgatga tgacgctcct aaaccagagc aaccagaaca
     1381 gccagagaag ccggagcaac caaggaagcc acagcaggag cagcaaagcc taccacgtcc
     1441 aatagagggc aaccagtcat tgccaaaaac acatgaggca aaaggtgtac tggctctagt
     1501 aggagtagga atccttgcta tgctaggact aggcttttgg tttagacctt atcaaaaaga
     1561 ctaaatcaag gctcagcagc tatttaagct aaacagctgt gctcagctaa atgataaaac
     1621 aattaagatt ggagaatgtg gctattagta gcttctccaa tcttttttga tagcagcatg
     1681 tgctttttct gccgtatttt attgagaata atagttgacc agtctaggcg attttgctag
     1741 aatagagagg tcgcaagaca gactaacttt ttcttggttt taggagtgcc aaccctaaaa
     1801 ctcggattaa gcaaaaaagg agaattatta tggcaatctc aaaagagaaa aaaaatgaaa
     1861 ttattgcaca atatgcacgt cacgaaggtg acacaggctc agttgaggtt caggtagctg
     1921 tccttacttg ggaaatcaac cacttgaaca accacatcaa ggagcacaaa aaagaccacg
     1981 caacttatcg tggattgatg aaaaaaatcg gacaccgtcg taacctatta gcatacctac
     2041 gtcgtacaga tgttaaccgt taccgcgagt taatccaatc acttggactt cgtcgttaat
     2101 tggcttgaca gaggtcattt tagagataac caagttctat tgaaaaaaga tctgct
//
LOCUS       DARYXW010000138         2105 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.139, whole genome shotgun sequence.
ACCESSION   DARYXW010000138 DARYXW010000000
VERSION     DARYXW010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2105)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2105)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2105
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.139"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(109..792)
                     /locus_tag="TV191_001856"
     CDS             complement(109..792)
                     /locus_tag="TV191_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HEL1508332.1"
                     /translation="MLLDVVIQFRDRRSTITIDTPSTCPHCGRTMSPQHVGESKSSDN
                     ESYSYQGHFSVIFRCSFDDCLKYFAVEYIHDQIGKGSAVAYFYRPPIRVNLPENVDKV
                     SPAFVEIYSQATIAEQEKLDQIAGVGYRKAAEFLIKDYTISKNPDDSDNIKQIMLGKV
                     ISDYLSDFPKLQALSRSVAWIGNDETHYVRRHNNKDLQDLKRFILAAAQFVAADYDAD
                     DALSFTSTD"
     gene            850..1038
                     /locus_tag="TV191_001857"
     CDS             850..1038
                     /locus_tag="TV191_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508333.1"
                     /translation="MEETASVNVTVKINNITEFSTLVEKFNEKARELEAISHELMRFK
                     FQGEIESRALSDNANEIE"
     gene            complement(1012..1479)
                     /locus_tag="TV191_001858"
     CDS             complement(1012..1479)
                     /locus_tag="TV191_001858"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508334.1"
                     /translation="MDLNQVRLLEACHRYLVDRVHIDIKENMLNDKLVFEFNGDFVTF
                     NTYQEVGHCCFYEYELGSYEELENHRSIDVTEILSILNLKSGQIGTLSMLTDITRVRA
                     YIFKLLSQADFAKFEKEIKNTNFAYNFRYVENYSYLPCVKIDKDKLFNFVSII"
     gene            1553..1741
                     /locus_tag="TV191_001859"
     CDS             1553..1741
                     /locus_tag="TV191_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1508335.1"
                     /translation="MQILLYKLRKEKRISQEEMSKVINKSSNTYRDKELGKRDFTQSE
                     MFKIANFFHKELGEIFTP"
     gene            1792..>2105
                     /locus_tag="TV191_001860"
     CDS             1792..>2105
                     /locus_tag="TV191_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001072522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antA/AntB antirepressor family protein"
                     /protein_id="HEL1508336.1"
                     /translation="MNQLINITLNENQEPVVSGRDLHKVLEIKTAYKDWFPRMAEYGF
                     EEGQDFSSFLSKSTGGRPSQDHVLKLDMAKEIAMLQRNEKSKQVRKYFIQIEKDFNSP
                     EK"
BASE COUNT          728 a          367 c          395 g          615 t
ORIGIN      
        1 tggaaggagg aacgatatga acgaactaga aagaacagcc cttaatgaaa tcatgaggac
       61 agtgacttat atagcggaga agctggataa aattgattct aagatttctc agtctgtaga
      121 agtgaacgat agtgcatcgt cagcgtcgta gtctgccgca acaaattgag cagctgctaa
      181 aataaaacgt ttgagatcct gcaagtcttt attattatgt ctacgaacat aatgagtttc
      241 atcgttacca atccacgcca ccgagcgaga tagagcttgg agtttaggga agtcggagag
      301 atagtcacta attacttttc caagcataat ttgtttgatg ttgtcgctgt cgtcaggatt
      361 ctttgatatt gtataatctt tgattaaaaa ctcagcagct ttacggtaac caacacctgc
      421 aatttgatcg agtttttctt gctctgcaat tgtagcttgg gagtatatct ctacaaatgc
      481 tggcgacact ttatcaacgt tttcaggaag attcactcta ataggtggac gatagaagta
      541 ggcgacagct gatcctttac caatctgatc gtggatatac tctacagcaa aatattttaa
      601 gcaatcatcg aaagagcaac ggaatatcac tgaaaaatgc ccctgatatg aataactttc
      661 attgtcagaa cttttgcttt cgccaacgtg ttgaggggac atagttcgac cacagtgggg
      721 gcaagtcgaa ggtgtatcaa tcgtgattgt acttctacga tctctaaatt gtataactac
      781 atcaagcaac attattattt ctctccaatc gttttattta aattatacca cagaaagggg
      841 gtggggaaga tggaagaaac agcctcagta aacgtaactg taaaaattaa taacataact
      901 gagttttcaa ctttagttga aaagttcaac gaaaaagccc gtgagttaga agcgatttct
      961 cacgagctaa tgcgtttcaa atttcaaggc gagattgaaa gtcgtgcgct atcagataat
     1021 gctaacgaaa ttgaataatt tatctttatc aattttaacg cacggtaagt aactataatt
     1081 ttcgacatat cgaaaattat aggcaaaatt agtatttttg atttcttttt caaattttgc
     1141 aaaatccgct tgggatagaa gtttgaaaat ataagctctt actcttgtta tgtcggtaag
     1201 cattgagagt gtaccaattt gccctgattt taagtttaag atgctcaaga tctcagtaac
     1261 atcaatactt ctgtggtttt ctagctcttc atatgagccg agttcatact cataaaagca
     1321 gcaatgccca acttcttgat atgtattgaa agtcacaaag tctccgttga attcaaaaac
     1381 tagtttgtca ttaagcatat tttctttgat gtcaatatgt actctatcaa caagatatct
     1441 atgacaagct tccaataatc gaacttgatt taaatccatc acattcacct cctttctgcc
     1501 catattatag cagattagag gtactaaaaa cagatagaaa ggaggtgggg gaatgcagat
     1561 tcttctgtat aaactgcgaa aagaaaaaag aatttcacaa gaagagatgt ctaaggttat
     1621 taataagtct tctaacactt accgagataa agaattaggt aaaagagact tcacacagag
     1681 tgaaatgttt aaaatcgcca atttctttca caaagaatta ggcgaaattt ttacaccata
     1741 aacttcacga aacgtgaaat ataaatcaac acaacactag aaaggaacaa catgaatcaa
     1801 ctaataaaca tcaccctaaa cgaaaatcaa gaaccagttg tcagtggtcg tgatttacat
     1861 aaagtacttg aaatcaaaac agcttataaa gattggtttc caagaatggc tgaatatggt
     1921 tttgaagaag gtcaggactt tagctcattt ttgagcaaaa gtacaggagg tcgtcctagt
     1981 caagaccacg ttctaaaact agacatggca aaagagattg ctatgttaca gcggaatgaa
     2041 aaatctaagc aagtccgcaa gtattttatt caaatcgaaa aagactttaa cagccccgag
     2101 aaaat
//
LOCUS       DARYXW010000139         2049 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.140, whole genome shotgun sequence.
ACCESSION   DARYXW010000139 DARYXW010000000
VERSION     DARYXW010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2049)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2049)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2049
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.140"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(234..866)
                     /locus_tag="TV191_001861"
                     /pseudo
     CDS             complement(234..866)
                     /locus_tag="TV191_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(868..1635)
                     /locus_tag="TV191_001862"
     CDS             complement(868..1635)
                     /locus_tag="TV191_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HEL1508337.1"
                     /translation="MEQKLNHLAVGEFVLLLPEHLRSEEEHYKSVFEDDLTSRMSSQD
                     GRQQMIATVAYLESGQDRFVYNTTPISYQQFLKDPIIIVVTPQSTGPQSVMFWFDAVQ
                     NYVLFNQLSDAQELIQRQDIENWVSEMQSGYQNYITLLNNIQRERWIMLAGAVLGIAT
                     SILLFNTMNRLYFEEFRRAIVIKRIAGLRFLEIHRNYLLAQLGVFLLGFVASVFLQVE
                     IVIAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            complement(1917..2049)
                     /locus_tag="TV191_001863"
                     /pseudo
     CDS             complement(1917..2049)
                     /locus_tag="TV191_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795769.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
BASE COUNT          617 a          415 c          369 g          648 t
ORIGIN      
        1 tcccttattt tactgctaaa ttatcctttg taaaagaaga tattaatcgt tataaagacc
       61 aaaaaagaga agaccaaaat gatcccctct agtcttcttt tcggcatatt ttaccgttat
      121 ttggccaact ttccactaat gtgagtaaaa ttgtattcta agcaagcttt acctattaac
      181 ttaggagaaa acataatctc tatagctaaa aataccaaaa aaattatgaa tcattatcgc
      241 aaactatcca tagtgatcac ttcatcagcc atttcccata ttgctggatt atgagttgct
      301 acgatgatta atctgttagc gtcacgaaga gacagtacaa tctccataat caacttggac
      361 gtggttggat ctattgaagc cgttggttca tctgccaaaa taaatggcgg attttttaag
      421 atgatctttg ctaaggcaac tcgttgtgac taacccccag atagctcaaa aatgcgttta
      481 tctaggttca gataggataa acctacacgt tctaaggcct gtttctgtct catcgtttgc
      541 tcagatttat tcaatttttg accaatgaga ccaagtttga ggttttcttc aatcgtttga
      601 ttttcaatca aaccaaaatt ttggaatagg taacccaatt catgacggaa aaaatcacta
      661 gatttatagc tggctaagtc tttgtctcgg taaaaaatag tcccatgata aggttctaat
      721 ttccccatca tgttcatcaa ggttgttttc ccgctaccgc ttgaaccaat caaagcatag
      781 acttttccaa cctcaaatgt cattgaaaga ttagaaaata gctctcgttc tccaaaagat
      841 ttactcactt gtttaagttc aatcatgtta acctcctttc aaaacaagca tggacatctt
      901 gttttctttc tgcatttgaa catgtaattg taaaagagat aggccagtga agagcaacaa
      961 tactaagaaa gcaatcacta tctctacttg aaggaataca ctcgcaacaa atccgagtaa
     1021 aaagacaccc aattgagcca ggaggtaatt ccgatggatt tctaaaaatc ttagtccagc
     1081 aatacgtttg atgacaatgg cacgtctaaa ttcttcaaag tagagcctat tcatggtgtt
     1141 aaacaacaag attgaggttg ctatcccaag cacagctccc gcaagcatta tccaacgttc
     1201 cctctggata ttattcaaca atgtgatgta gttctggtat cctgattgca tttctgagac
     1261 ccaattttca atgtcctgtc tctggataag ctcctgggca tcggacaact gattaaagag
     1321 gacataattc tgtaccgcgt caaaccaaaa catgacggac tgaggtccag ttgactgggg
     1381 tgttacgaca atgataatcg gatctttcag aaactgttga taggaaatag gtgtcgtatt
     1441 atacacaaaa cggtcttggc ctgattccaa ataagccacc gtcgcaatca tttgctgtcg
     1501 accatcttga ctagacatgc gactagttaa gtcgtcttca aaaacagatt tgtaatgttc
     1561 ttcctctgaa cggagatgct caggcaagag caagacaaat tcccctactg cgaggtgatt
     1621 cagtttttgt tcaatagccg tatctacagg gatgttttga cgctccaagt attgcggtgt
     1681 gacaataagg acattgccat ttgggctgta atcttgccat tctgtagaag ttgtcaagtt
     1741 tttggaaaag tcttagcctt tgttatcaat acttgagtag cacctatgtt tttcagatta
     1801 gcttgctctt gtaactgttc tgagctatta aatgctgtca tttcaacggt gatattttca
     1861 gttgattctg cctgcttgtt atcttctttt gttggagatt ctggacgttt ctcaaaataa
     1921 aaataattat aaagctgttg agccgttact cctccaccag cccagccagc aacaggttga
     1981 ccattcttca gatatagtat tgttggtgtt cctgggattc caactgtttt aaataaaaac
     2041 tcctgagct
//
LOCUS       DARYXW010000140         2002 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.141, whole genome shotgun sequence.
ACCESSION   DARYXW010000140 DARYXW010000000
VERSION     DARYXW010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2002
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.141"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            3..695
                     /locus_tag="TV191_001864"
     CDS             3..695
                     /locus_tag="TV191_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEL1508338.1"
                     /translation="MAMKLLITSGGTTEAIDAVRGITNHSTGQLGKIVAETFLAKGFD
                     VTLVTTKTSVKPAQQPHLTIREVTNVDQLMAILKEEVPKHDLLIHSMAVSDYSPVYMT
                     DFDTVAAADHLQTFLTASNKEAKISSAADYQVLFLKKTPKVISYIKEWNPNIRLVGFK
                     LLVNAPAEELISVARDSLHKNKADYIVANDLADIKANQHKAFLVNDKTVCSASTKEEL
                     AQLIYERIIAND"
     gene            688..1233
                     /gene="coaC"
                     /locus_tag="TV191_001865"
     CDS             688..1233
                     /gene="coaC"
                     /locus_tag="TV191_001865"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEL1508339.1"
                     /translation="MTKRITLAVSGSISAYKAADLTSQLTKKGYEVTVLMTQAATAFI
                     TPLTLQVLSKNPVHLDVMAEHDVKIVNHIELAKATDLFVLAPASANTIAHLAYGFADN
                     MVTSVALALPEATPKLIAPAMNTNMYLNPITQGNIKRLADLGFREIPPKTALLACGDR
                     GPGALADIDDMVTAISQQLAR"
     gene            1290..1862
                     /locus_tag="TV191_001866"
     CDS             1290..1862
                     /locus_tag="TV191_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL1508340.1"
                     /translation="MNHNKSSEISRIAIFFAVMLVIHFISSWFFYIWPVPIKPTLVHI
                     PVIVASIMYGPRTGAILGGLMGIVSVITNTLVLLPTSHLFSPFVTNGNLASLMIAMLP
                     RILIGITPYYCYKLIKNELGLVLAGLVGSLTNTIFVLSGIFIFFPTASGDNVKTFLTT
                     IVSGNAITEMIVSAIVTITLIPALSKLKKS"
BASE COUNT          594 a          442 c          383 g          583 t
ORIGIN      
        1 atatggctat gaaattatta atcacatcag gcggaacgac cgaagcaata gacgccgtta
       61 gagggattac caatcattcc actggccagc taggaaagat agtagctgag acctttctag
      121 caaagggatt tgacgttact ctagtgacaa caaaaacttc agtaaaacca gcacagcagc
      181 ctcatttgac cattcgtgag gtgaccaatg ttgatcagct gatggctatc ttaaaagagg
      241 aggttcctaa gcacgacctt ctcattcaca gcatggctgt ttcagattat agcccagtgt
      301 acatgacaga ctttgataca gttgcagctg ctgatcattt acagaccttt ttaacagcaa
      361 gcaataagga agccaaaatc tcatcggcag ctgattatca ggtgctcttt cttaaaaaaa
      421 cacctaaagt catatcctat attaaggaat ggaatcctaa tataaggcta gtcggcttta
      481 agctattggt caatgctcca gctgaggagc taatttcagt ggcacgagat agcctgcata
      541 aaaacaaagc agactatata gtagccaatg acctagcaga tattaaggcc aatcagcaca
      601 aggcttttct tgtcaatgac aaaacagtct gctctgccag caccaaagag gagcttgcac
      661 aattaatcta tgaaaggata atagccaatg actaagcgaa taacacttgc ggtctcaggt
      721 agtatttctg cctataaggc agctgatctc accagccaat taaccaaaaa aggctatgag
      781 gttactgtgt tgatgacgca agcagctact gcctttatca ctccgttgac cctacaggtc
      841 ttatcgaaaa atcctgtcca tctagatgtc atggcagagc acgatgtcaa aattgtcaat
      901 catattgagc tagctaaagc aacagatcta tttgtccttg ctcctgcaag tgccaatacc
      961 attgctcatt tagcctacgg ctttgctgat aatatggtta ccagtgtcgc cctagccctg
     1021 cctgaggcaa cacccaaact catcgctcct gctatgaata ctaacatgta ccttaaccca
     1081 attactcagg gaaacatcaa acgcttagct gatcttggct ttcgagaaat accacctaag
     1141 acagcactcc ttgcctgcgg cgacagagga cctggggcct tagcagatat tgatgatatg
     1201 gttacagcaa ttagtcagca gctagcaaga tagctggtca ccgattagca attgctgtat
     1261 tataatataa aaatttaatg gagaatgcaa tgaatcataa caaatcttct gaaatctctc
     1321 gtattgccat cttttttgca gtcatgctgg ttattcactt cattagtagc tggttttttt
     1381 atatctggcc tgtcccaatt aaaccaacac tcgtccatat tccagttatt gttgcttcta
     1441 tcatgtatgg tccgcgcact ggagctatct taggaggctt gatggggatt gtcagtgtga
     1501 tcacaaatac cttggtttta cttccaacaa gccatctttt ctcaccattt gtcacaaatg
     1561 gtaatctggc ttccttgatg atcgctatgc tgcctcgtat cctgattggg atcactcctt
     1621 attactgtta taagcttatc aaaaacgagc ttgggcttgt cctagctggt cttgttggct
     1681 cgctgacaaa caccattttt gttctctcag gaatatttat ctttttccca acagcctctg
     1741 gtgacaatgt caaaacgttt ctaactacca ttgtatctgg caatgctatt actgaaatga
     1801 ttgtttcagc tatcgttacc attactctta tcccagcttt atccaagctc aaaaaatcat
     1861 aatattgctc aagctatgaa gcatgctgtc tgataaggat agcatgcttt aatgatatgt
     1921 gacaagcaag gaaattgatc cttatgtgaa aaaatgattg gaagctatta cagaaaataa
     1981 gtgatttttc cttttcaaca tg
//
LOCUS       DARYXW010000141         1998 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.142, whole genome shotgun sequence.
ACCESSION   DARYXW010000141 DARYXW010000000
VERSION     DARYXW010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1998)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1998)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1998
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.142"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            153..1823
                     /locus_tag="TV191_001867"
     CDS             153..1823
                     /locus_tag="TV191_001867"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018375545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEL1508341.1"
                     /translation="MKSDIEIAQSVPLKPITEIVKKVGIDADDLELYGNYKAKLSFEK
                     IKSVEDNKPGKLILVTAINPTPAGEGKSTMSIGLADALTKIGKKTMLALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTAHNALSALIDNHLQQGNELGIDPRR
                     IIWKRVLDLNDRSLRQVIVGLGSPVNGVPREDGFDITVASEVMAILCLATDLKDLKAR
                     LANIVIAYRYDKSPVYVRDLKVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATSTALRLADYTVTEAGFGADLGAEKFLNIKTPNLPKAPDAVVIVATLRAL
                     KMHGGVAKADLTFENTAAVRSGFANLKRHVENIRKFNIPIVVAINEFVTDTKAEIQVL
                     KELCAEIAVPVELASVWAKGADGGIALANAVVKAITEESAAYKRLYADKDSLEEKLKA
                     IVTEIYGGRAVQFGPKAKNQLKQFAQFGWDQLPVCMAKTQYSFSDDPSLLGAPDQFDI
                     TIRELVPKTGAGFIVALTGDVMTMPGLPKIPAAMKMDVTEDGTAVGLF"
BASE COUNT          561 a          380 c          462 g          595 t
ORIGIN      
        1 aattattttt actgacaatg ctgacgctac taagcttttt tcctttcaga accattataa
       61 aaacgaacat ttttgtatat agaacaaatc aatgtacgtt tgagatgaag tgtgatataa
      121 taacactatc aagtaagagt caaggagttt tcatgaaatc agatatcgaa attgctcaaa
      181 gtgtcccctt aaagccgatt acagaaatcg ttaaaaaggt ggggattgat gctgatgatt
      241 tggagcttta cggtaactac aaagccaaat tatcctttga aaaaatcaaa tcagtagagg
      301 acaataagcc tggtaagctc attttagtga ctgctattaa tccaacgcca gcaggtgaag
      361 gcaaatcaac catgtctatt ggtttggcag atgccttgac taaaatcggt aaaaaaacca
      421 tgctggcctt gcgtgagccc tctttaggac cggttatggg gatcaaaggt ggtgctgcag
      481 gtggcggcta cgctcaggtt cttccgatgg aagatattaa ccttcatttt accggggaca
      541 tgcatgctat taccacagct cataatgctt tatcagccct tattgataat caccttcagc
      601 agggcaatga gcttggtatt gacccgcgtc gtatcatctg gaagcgtgtc cttgatttga
      661 atgaccgttc tcttaggcag gtcattgttg gcttggggag tcctgtcaat ggtgtcccaa
      721 gagaagacgg ttttgatatt acagtagcct ctgaagtgat ggctatcctt tgcttggcga
      781 ctgatcttaa ggacttgaag gctcgtttag ctaatattgt gattgcctat cgttacgata
      841 aatcacctgt atatgtgcgt gatttaaagg tagaaggggc attagccttg attttgaagg
      901 acgccatcaa gcctaacctt gttcaaacaa tctatggtac accagccttt gtgcatggtg
      961 gaccctttgc caatattgct catggctgta attctgttct ggcgacatca acagctttgc
     1021 ggttggcaga ttatactgtt acagaggcag gctttggagc ggatcttgga gcagaaaaat
     1081 tccttaacat caaaacaccg aatctaccta aggctcctga tgcagttgtt attgtcgcaa
     1141 cacttcgtgc cttgaagatg catggcggtg ttgctaaggc ggatttaacc tttgaaaata
     1201 cagctgcggt ccggtctggc tttgctaatt taaagcgtca tgttgagaat attcgaaaat
     1261 tcaatattcc gattgttgta gctatcaacg aatttgtgac agatactaaa gcagaaattc
     1321 aagtcttaaa agaattgtgt gcagaaatag ctgttccggt tgaattggca agcgtgtggg
     1381 ccaagggggc tgatggcggt attgctcttg ccaacgctgt tgtcaaggct attacagagg
     1441 aaagcgcagc ctataagcgt ctatatgcag acaaggatag cttagaggag aaacttaagg
     1501 caattgtgac tgaaatttat ggtggtaggg ctgtgcaatt cggacctaaa gctaaaaatc
     1561 agctcaagca atttgcccag tttggttggg atcaattgcc tgtttgcatg gccaaaaccc
     1621 agtatagctt ttcagacgat ccatcgctcc taggcgcgcc agatcagttt gacattacca
     1681 ttcgtgaatt agtgcctaag accggtgccg gctttatcgt cgccttaact ggagatgtga
     1741 tgacaatgcc aggcttgcca aagattcctg cagctatgaa gatggacgtc accgaagacg
     1801 gtacagcagt aggattgttt tgatttattt gttatagcca gaatcaggat tgaagaaagc
     1861 ttcagaaagg gggtttcttc aatctttttt aatgtctaag gataagctga taacaatagc
     1921 tcatatttta ctattttaat cgttattcac aatctttttt taccagtata ggtgtcatat
     1981 tgacaatcat taatgctt
//
LOCUS       DARYXW010000142         1931 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.143, whole genome shotgun sequence.
ACCESSION   DARYXW010000142 DARYXW010000000
VERSION     DARYXW010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1931)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1931)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1931
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.143"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            146..361
                     /locus_tag="TV191_001868"
     CDS             146..361
                     /locus_tag="TV191_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002838961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HEL1508342.1"
                     /translation="MDFFVQAVNVLKILVMAIGAGLGAWGVINLLEGYGSDNPGAKSQ
                     GIKQLMSGGGIVLIGLKLIPLLANVLR"
     gene            361..1224
                     /locus_tag="TV191_001869"
     CDS             361..1224
                     /locus_tag="TV191_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508343.1"
                     /translation="MFDLFGKIEEFFKDIMIDIIKDNLSAMLVDINDKVGTVAGEVGK
                     TPSSWNSEVFTFIKSINTNVVLPIAAIILTAILCIELIQVVMRKNSMHDTDTFEFFKY
                     IIKMWIAVWLVSHAFDFSMAVFDVAQSMIGKAAGVVGTSANITPGNFDAMVEALKTKE
                     LGTLIGIALETGLVKFSLTILSILITVILYGRMIEIYIYCSVAAIPFSTMGNKEWSNI
                     GTNYIKSLFALGLQGLFILIFFGIYAVLVKTVNFTDIHTSILQVLAYGLILGVMMMKS
                     GSIAKAILNSH"
     gene            1297..1791
                     /locus_tag="TV191_001870"
     CDS             1297..1791
                     /locus_tag="TV191_001870"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1508344.1"
                     /translation="MNKINKKTRILIGAGSALSIGTIITVLLKKKTKKLSDLEEDDFD
                     FDFDEIEEDSCVNDKFATENDKDDTVKGEIDFLVDESKTENEKQEEFRDLSVKVMDLL
                     LKEVISMSETLNLVKRDIDRIGEVKALVEELENCKEEIISLWEHMEKLSDLREEITGK
                     KNRG"
     gene            1795..>1931
                     /locus_tag="TV191_001871"
     CDS             1795..>1931
                     /locus_tag="TV191_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004804452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HEL1508345.1"
                     /translation="MAYVKIPKDLTKVKTKVALNMTKRQLIGFSIAGLIGFPVYMLCK
                     N"
BASE COUNT          707 a          243 c          410 g          571 t
ORIGIN      
        1 aaataaaatg aaaaatataa taaaatcaat aaggataaga agtccaactt taagaaaatt
       61 gaatagcaaa agtttaacga ttggaagaga agatttccag tcgttttttt atgaaaataa
      121 gtaaaataat gaggaggaat aaattatgga tttttttgta caggcagtaa atgtgcttaa
      181 aattttggtt atggcaatcg gtgcaggact tggtgcatgg ggagttatca acttacttga
      241 aggatacgga tcagataatc ccggtgccaa gtcgcaagga atcaagcaat tgatgagcgg
      301 tggaggaatt gttttaatag ggctgaaact aattccgcta cttgctaatg tcttgagata
      361 atgtttgatt tatttggaaa gatagaagag tttttcaagg atattatgat tgatattatt
      421 aaagataatc tttctgcaat gcttgtggat attaatgata aagtaggaac cgttgcagga
      481 gaagtgggaa agactccgag ttcttggaac tcggaggtct tcaccttcat taaatcaatc
      541 aataccaatg ttgttttacc catagcagcg ataattctaa ccgcaatact ttgcatagaa
      601 ctgattcagg tggtaatgag aaaaaattct atgcacgata cggatacctt tgaatttttt
      661 aagtacatta ttaaaatgtg gatagctgta tggcttgtgt ctcatgcgtt tgatttttca
      721 atggcagtct ttgatgtggc acagtccatg ataggaaagg cagcaggtgt tgtggggaca
      781 agtgcgaata tcacaccggg aaattttgat gctatggtag aagcccttaa aacaaaggaa
      841 cttggaacac tcattgggat tgcactggag acgggattag ttaaattttc tttaacgatt
      901 ctatcaatct taatcactgt aatcctatat ggaagaatga ttgagatata tatctattgc
      961 tctgttgcgg caattccatt ttctacgatg ggaaataaag aatggtcaaa tatcggaaca
     1021 aactatataa aaagtctatt tgcccttgga cttcagggac ttttcatcct aatatttttt
     1081 ggaatttacg cagtcttagt caaaaccgta aactttacgg atatccacac aagtatttta
     1141 caggtattgg catatggatt gattcttgga gtaatgatga tgaaatccgg aagtatagca
     1201 aaggcgattt taaacagtca ctaaaggact ttagttcaaa atgagcaaaa gttgatgaaa
     1261 taatcagaac aaaaaatata attattggag gtaagaatga ataaaataaa taaaaaaaca
     1321 aggattttga taggagcagg ctcagccctt tctatcggga caattattac agtgctatta
     1381 aaaaagaaaa cgaaaaaatt atccgatctt gaagaagatg attttgactt tgattttgat
     1441 gaaatagaag aagattcttg tgtcaacgat aaatttgcta cagaaaatga taaagatgat
     1501 acagtaaaag gagaaataga ttttttagta gatgaatcaa agacggagaa cgaaaagcaa
     1561 gaagagttta gagatttatc ggtaaaggta atggatcttc ttctaaaaga agtaatttca
     1621 atgagtgaaa ccttaaattt ggtaaaaaga gatattgata gaataggtga agtaaaagca
     1681 ttggttgaag aactggaaaa ctgtaaagaa gaaattatct cactttggga gcacatggaa
     1741 aagttatccg atttaagaga agaaattacc ggcaaaaaga atagaggtta ggctatggct
     1801 tatgtaaaga taccaaaaga ccttacaaaa gtaaaaacca aggtagccct gaatatgaca
     1861 aaaaggcagc ttataggttt tagcatagca gggcttatcg gttttcctgt atatatgctg
     1921 tgtaaaaatt t
//
LOCUS       DARYXW010000143         1924 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.144, whole genome shotgun sequence.
ACCESSION   DARYXW010000143 DARYXW010000000
VERSION     DARYXW010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1924)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1924)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1924
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.144"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            10..1140
                     /locus_tag="TV191_001872"
     CDS             10..1140
                     /locus_tag="TV191_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009855141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1508346.1"
                     /translation="MILRKYNDFCRLFLGRLISNCGDSIYTLVLSWYVLETTNSTWYV
                     GLLNFLIFIPNTFSFIFGKKIDSYPKKNLLVILEWAQLLAVLGIILGMSLREIHASLS
                     LTIIFSCVFLASMVGLNTYTVQDALVPKLIPTKDLAKAEMYMSVAYNGTDYVFTAISG
                     FLLSVISYIPLLFINIVTFLGSILFFRRIAFKEIIEQTNERTDFLSGLRFIWHNKVVL
                     AITLGGAIANFLFASLNVYQLLIAREVGNSAFYGLLVSVSAIGTLVGTTFVANLVLQK
                     LSVGKAFWLATTLLGTGIGLTALVPNRFGLLLLWFLSCLFLGITHVTQKPILRTEIPD
                     EHLGEVFSAFYTVTIPTLALGSLILISLLYFSNKMLRQYDIC"
     gene            complement(1484..1567)
                     /locus_tag="TV191_001873"
     tRNA            complement(1484..1567)
                     /locus_tag="TV191_001873"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1531..1533),aa:Leu,seq:caa)
     gene            complement(1586..1657)
                     /locus_tag="TV191_001874"
     tRNA            complement(1586..1657)
                     /locus_tag="TV191_001874"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1623..1625),aa:Gln,seq:ttg)
     gene            complement(1666..1738)
                     /locus_tag="TV191_001875"
     tRNA            complement(1666..1738)
                     /locus_tag="TV191_001875"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1703..1705),aa:His,seq:gtg)
     gene            complement(1750..1820)
                     /locus_tag="TV191_001876"
     tRNA            complement(1750..1820)
                     /locus_tag="TV191_001876"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1786..1788),aa:Trp,seq:cca)
     gene            complement(1827..1907)
                     /locus_tag="TV191_001877"
     tRNA            complement(1827..1907)
                     /locus_tag="TV191_001877"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1871..1873),aa:Tyr,seq:gta)
BASE COUNT          550 a          409 c          370 g          595 t
ORIGIN      
        1 ggatacaata tgatattaag gaaatataat gatttttgcc ggttatttct ggggcgactg
       61 attagcaatt gcggtgactc gatttatacc ctagtgctgt cctggtatgt actagaaacc
      121 actaatagta cttggtatgt tggattattg aactttctca tttttattcc aaacaccttc
      181 tcctttatct ttggaaaaaa gattgattcg taccctaaga agaacctgct agtgattctg
      241 gagtgggccc aattattggc tgtcttaggt attattttag gaatgtcctt aagagagata
      301 cacgcaagtc ttagcttaac cattattttt agttgtgttt ttctggcttc tatggttggg
      361 ttgaatacct atactgttca agatgctctt gtacctaaac tcattcctac taaagatcta
      421 gctaaagcag aaatgtatat gtcagtggct tataatggaa cagattatgt ttttactgcc
      481 atcagtggct ttttgctttc tgtgatcagc tacattcctt tgcttttcat taatatcgtt
      541 accttcttag gttcaatcct attttttaga agaatagcat ttaaagaaat aattgaacaa
      601 acaaatgaac gaacagactt tttaagtggc ttgcgcttta tctggcacaa taaagtggtg
      661 ttagccatca cattgggagg tgctatcgct aatttccttt ttgccagctt aaatgtctat
      721 cagttattaa tagcaagaga ggtagggaat tcagcttttt atggcctctt agtatctgta
      781 agtgctatcg gaaccctggt aggaacaacc tttgttgcta accttgtctt gcaaaagtta
      841 agtgtaggaa aagctttttg gctagcaact acccttttgg gcaccggtat tggccttaca
      901 gcattagtcc ccaaccgttt tggtttgttg cttctttggt ttctttcctg tctatttctc
      961 ggaataacgc atgttaccca aaaacctatt ttacgaactg agattcctga tgagcatctt
     1021 ggtgaagttt tcagtgcttt ttataccgta accatcccaa cacttgcctt gggttcgctt
     1081 atcttaatta gtctgcttta tttctcaaac aagatgctaa gacaatacga tatttgctaa
     1141 agcgtcatta accagagaac acatgataac tgatattgcg acattaatca aaaccaaacg
     1201 taaagaaaaa gctcacccac aaagaattgg ctaaaagtcc tagtatccaa agctcacatc
     1261 acacatgcct tggagcaacc ttattccaaa ttcaaacgct aagctgcacg ccactaacag
     1321 gtgatcaaag acatcaagcg caatgctttg gatttaggag ctttgaagcc aagattctca
     1381 ttacctttaa catctagaga ggaccaatct gatcctctga catcaagtca taaaacaaaa
     1441 aaacaaggtt tacaaacctt gttttttcaa tatttttaaa ctataccggc ggccggggtc
     1501 gaaccggcac gtccttgcgg acactggatt ttgagtccag cgcgtctgcc aattccgcca
     1561 cgccggcttt aagtataaaa ctaaactggg gtagctggat tcgaaccaac gcatgaggga
     1621 gtcaaagtcc cttgccttac cgcttggcta taccccaata aaataggcga gtgatgggaa
     1681 tcgaacccac gaatgtcaga gccacaatct gatgtgttaa ccacttcacc acacccgcca
     1741 tattctgaac acgggcagta ggaatcgaac ccacactgaa ggttttggag accttagttc
     1801 tacctttaaa ctatgcccgt tcaggatgga aagagaggga ttcgaacccc cgaacccgaa
     1861 ggagcggatt tacagtccgc cgcgtttagc ctcttcgcta tctttccaaa acatattaaa
     1921 ttac
//
LOCUS       DARYXW010000144         1917 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.145, whole genome shotgun sequence.
ACCESSION   DARYXW010000144 DARYXW010000000
VERSION     DARYXW010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1917
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.145"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(166..531)
                     /locus_tag="TV191_001878"
     CDS             complement(166..531)
                     /locus_tag="TV191_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEL1508347.1"
                     /translation="MYQVIEMYGDWEPWWFIDGWQDDIVQEKSFDSWPAALAYFEEEW
                     QRMKKSYPSYHSQKSLLATFWREDERRWCEDCDEELQQYHSLLLLKDRDIVPKHHYQS
                     YFEQRNDCPQASLSCKLSI"
     gene            complement(592..1638)
                     /locus_tag="TV191_001879"
     CDS             complement(592..1638)
                     /locus_tag="TV191_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001868451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEL1508348.1"
                     /translation="MTKESQKVTDSLNTSVVSLLQYCFAIMVIVIHSGRLFQYEPLHF
                     FLKSFLGRMAVPYFLICTAFFLRGRLREANREKQYFKQILKTYLLWSLIYLPYAYAFF
                     ESLRLPKHYLPLGLCLALSYFGMCYHLWYIPALWLGWVLVQLSLKTFGKKVTLIIVAG
                     LYLLGSMETYSHFLSSTPFEPLLTGYMHIFQTSRNGIFYTPAYLCAGCLLYDHFSSSL
                     FSQRYMRKAAVCLILLALESLLIYHHQGLDKNFFLLSALFTTFLFNASVRISLLSKYS
                     LAKLKKLSYYYFFLHPMFIECSLFLLRPYQLAPATKGKLVFLMTLLATHLCSEALMLL
                     VRSQAHAKAYLKRQ"
BASE COUNT          627 a          409 c          366 g          515 t
ORIGIN      
        1 gattttatca taatgaggct cgctatgttg ttttctctat cccaatcagg cactgctaga
       61 ttagacatct ttccagacaa caaaaatagc ctaaggtcag ctctctaatt agctgatctt
      121 aggctatttg agtgataata gatttgactg atagctgtaa gcctctcaga tgcttaattt
      181 acagctaagg gaggcttgtg ggcagtcatt tctttgctca aaatatgact gataatgatg
      241 ctttggcaca atgtctctat cctttagcaa taaaagagag tgatactgct gcagctcctc
      301 atcgcaatcc tcacaccatc ttcgctcatc ttccctccaa aaggtagcca ataagctttt
      361 ttgactgtgg tagctgggat agctcttttt catgcgctgc cattcttcct caaaataagc
      421 cagtgcagca ggccagctgt caaacgattt ctcctgaaca atatcgtctt gccaaccatc
      481 tataaaccac caaggctccc agtctccata catttcaatc acttgataca tgttctcatt
      541 tcctctattg cctattatag ccgaagaaag atatttttaa aaaacatctg ctcactgcct
      601 tttaagatag gccttggcat gagcttgaga acgtaccagc agcataaggg cctctgagca
      661 aagatgagta gctagcaggg tcatgagaaa gaccagtttc ccttttgtgg ccggggcaag
      721 ctggtagggc cttagcagaa atagcgaaca ttcgataaac attgggtgca agaaaaaata
      781 ataatagctt agctttttta atttagctaa agaatattta gacagaaggc tgatacggac
      841 actggcattg aataaaaagg tagtaaacag cgcagaaagc aagaagaaat ttttatccag
      901 accctgatga tggtaaataa gcaggctttc caaggccaat aagatcaggc aaacagccgc
      961 ctttctcata tacctctgag aaaaaagcga cgatgaaaag tgatcataga gcaagcagcc
     1021 cgcacaaaga taagcagggg tgtaaaaaat accattgcga cttgtttgaa aaatgtgcat
     1081 gtagcctgtc agcaaaggct caaaaggcgt cgagcttaaa aaatgagaat aggtttccat
     1141 actccctagt aaatacaagc ccgccactat gatgagcgtt accttcttac caaaggtctt
     1201 cagagaaagc tgaacaagca cccaccccag ccataaagca ggaatatacc acagatgata
     1261 gcacatccca aaataactaa gggctaaaca caagccaagg ggaagataat gcttaggcag
     1321 acgaagcgac tcaaaaaagg cataagcata agggaggtaa atcagagacc aaagcaaata
     1381 ggtttttagt atttgcttga agtactgctt ttcccgattc gcctctctaa ggcggcctct
     1441 tagaaaaaag gcggtacaaa tgagaaaata aggcaccgcc attcttccta aaaagctttt
     1501 caaaaagaaa tgcagcggct catactgaaa cagcctaccg ctatgaataa caataaccat
     1561 tatggcaaaa cagtattgta acaggcttac cacagaggta ttgaggctgt cagtgacttt
     1621 ctggctctct tttgtcatca attcaatcac tttcttttaa gagattaata tacgtataac
     1681 ttttagtatt tatcgcattt gtctctcatt ttgattaata ttgtttttat catagcgtaa
     1741 tataaccaat taatctaatg attttagcat aacaaaagga gctaaggcta gctcctgaac
     1801 atcacaaaag agcagacgaa cttcatctcc tctcgtgctt agatataagc cacccactac
     1861 agttaacatg gagccataaa acgaaggaat taactccttc gttttctttc aattttt
//
LOCUS       DARYXW010000145         1889 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.146, whole genome shotgun sequence.
ACCESSION   DARYXW010000145 DARYXW010000000
VERSION     DARYXW010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1889)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1889)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1889
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.146"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            <1..273
                     /locus_tag="TV191_001880"
     CDS             <1..273
                     /locus_tag="TV191_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508349.1"
                     /translation="TIHVLTSGGKIEPDIYKGMLELIEPAKKGQYQEHDVFTVLDDKH
                     EDLAGEGKLVFVYVNEAFEYDKQTLKDLESEDKVTVIKYADLVKGK"
     gene            286..576
                     /locus_tag="TV191_001881"
     CDS             286..576
                     /locus_tag="TV191_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508350.1"
                     /translation="MIDFVQIGTFCGAALSIFGVWGFIVNPFKKALEANELAMAQLKD
                     SIKELAYELKNLDRDGEITKKIIDRHEERLGRVEDDIIVNKEQIKTLFKKGD"
     gene            579..758
                     /locus_tag="TV191_001882"
     CDS             579..758
                     /locus_tag="TV191_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508351.1"
                     /translation="MDKWFKKVAIKTIKTMAQTAVGVIGSSALITDVNWQVVASTVIM
                     SGIVCVLMNVSDIKE"
     gene            870..>1889
                     /locus_tag="TV191_001883"
     CDS             870..>1889
                     /locus_tag="TV191_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL1508352.1"
                     /translation="MTFLDDIKSAVIAEWHNHKILPSLTAAQAILESGWGKYAPHNAL
                     FGIKADSSWSGKSFDTKTQEEYQPGVVTDLVDRFRAYDSWDESILDHGQFLVDNPRYK
                     SVIGETDYKKACHAIKAAGYATASDYAELLIQLIEQNDLQKWDAEALAKRKESQMISS
                     QCREVIEFYINLANAGMGVDKDGAYGTQCADVPCYAAKHWFGVDLWGNAADLLDSASA
                     QGWEVHRMPTDANPRAGAFFVMDAWFGGINYGHTGLVYVDSDGYTMQTIEQNIDGNAD
                     ALYVGGPARFNTRDFTNVAGWFYPPYQGDVAAQTVSTDPQTSDTIVETSKSGTFTLDA
                     AEINVR"
BASE COUNT          549 a          362 c          475 g          503 t
ORIGIN      
        1 actatccacg ttttgacaag tggtggcaag attgagcctg atatctataa aggcatgctt
       61 gagcttattg agccagctaa aaaaggtcag tatcaagagc atgatgtctt tactgtgcta
      121 gatgacaagc atgaggactt ggccggcgag ggtaaacttg tctttgtcta tgttaacgag
      181 gcctttgagt acgacaagca aaccctcaaa gatctggaat cagaggataa agtcacagtt
      241 atcaagtacg ctgatttggt taaaggcaaa tagtgaggtg attagatgat agattttgtg
      301 caaataggca ctttttgtgg cgctgctctg tctatctttg gtgtttgggg atttatcgtc
      361 aatcctttta aaaaagcgct ggaggctaac gagctagcca tggcccaact caaagactcg
      421 atcaaggagc tagcctacga gctaaaaaat cttgatcgtg atggagagat aaccaaaaag
      481 attatcgatc ggcatgagga gcgtttagga cgtgtagagg acgacattat tgtcaataaa
      541 gagcaaatca aaacattatt taaaaaagga gactaaaaat ggataaatgg tttaaaaaag
      601 tagcaatcaa aacaattaag acaatggccc aaaccgctgt aggggttatt ggatcaagcg
      661 cattgattac tgacgtcaac tggcaggtgg tggcctcaac agttattatg tcaggtattg
      721 tctgcgtctt gatgaatgtg tctgacatca aggaatagca ttatgcgagc aatcacacga
      781 ttagcaatag tcctagcaat cgcaatacta tatttaccgc tatctgtgat tgctcttatc
      841 ttttatccgt ttttaggtga ggaggacaga tgaccttttt agacgacata aaaagcgcag
      901 ttatcgcaga gtggcacaat cataagattt tgccatctct gacggctgct caagctattt
      961 tagagagcgg ttggggcaag tatgccccac ataacgcatt gtttggtatc aaggcagata
     1021 gctcatggtc tggtaaatct tttgatacca agacacaaga ggagtatcag ccaggtgtcg
     1081 tgacggatct cgtggaccgc tttagagcct atgacagttg ggacgagtca atccttgatc
     1141 atggccagtt tttagtggat aatccacgat acaaatcagt tatcggggag accgactata
     1201 aaaaggcttg tcatgccatt aaagcagctg gttatgccac tgcaagtgat tatgcagagc
     1261 tgcttatcca actaatagag caaaacgacc tacaaaaatg ggacgcggaa gccctagcaa
     1321 aaagaaagga gtcacaaatg attagttcgc agtgtcgaga ggttatcgag ttttacatca
     1381 atttggctaa tgctggtatg ggtgttgata aggacggggc ttatggcacg caatgtgcag
     1441 atgtcccttg ttacgcagct aagcactggt ttggtgtcga tctctggggc aacgcagcgg
     1501 acttactaga tagcgcaagt gcgcagggct gggaagtcca tcgcatgcct acagatgcaa
     1561 atccacgagc tggggcattt tttgtcatgg acgcttggtt tggtggtatc aattatggtc
     1621 atacgggtct tgtgtacgtt gactcagatg gttacactat gcagactatc gagcaaaata
     1681 ttgatggtaa tgcagatgcg ttgtatgtag ggggtccggc ccgttttaat actcgtgact
     1741 ttactaatgt ggccggctgg ttttatcctc cttatcaggg agatgttgct gcacaaacgg
     1801 tcagcacaga cccgcaaacc tcagacacga tcgtagagac atcaaaatca ggtactttta
     1861 cacttgacgc cgcagagatc aacgtccgc
//
LOCUS       DARYXW010000146         1884 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.147, whole genome shotgun sequence.
ACCESSION   DARYXW010000146 DARYXW010000000
VERSION     DARYXW010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1884)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1884)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1884
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.147"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            61..366
                     /locus_tag="TV191_001884"
     CDS             61..366
                     /locus_tag="TV191_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508353.1"
                     /translation="MLAVSTLSFGSAATARVVSAATAHPAPYPIIDEWNYGVSDNYGY
                     SNDYVKSPNNIGSKSSVTNLWGTVKDRDSQKYGWANSSATKSWNDVRLNTHWNYFTF"
     gene            433..>1884
                     /locus_tag="TV191_001885"
     CDS             433..>1884
                     /locus_tag="TV191_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1508354.1"
                     /translation="MKLKLCIVGFFFCLIAAIGLVSINDTQKPIPLPIDGAFSIQGKS
                     NLSNEEVYQTISDLSKEKKVTIYKPVVQNSGQLTYIKFDNTNHEQLKSAPITGMYYTL
                     GKLDSNSLKPLTSTGLQVIYLAYPWQIGGMIQFTGPLRLLLMISIYLTLLVVLFVVRA
                     RQIKEGVIRRSLGLPVHDLRRDYFMSFTFELVMAALLMISYSSFLGSGFFTYSSKLFF
                     SMLLTNLIIFQIIDIITFVLFWLTIKVEKPIEIIKNKAKNSLIFIVWLAVISIIIVVS
                     GVFLRETKASQSKINMQIKHLKPWSAVKDWKRPEFLGIENESVTNGEEANDSGAKYVE
                     IAKALKKLDFIYIKSSSAYVPEYMAASDVTEDFSKQLKSDGITHPEVNKELVYINQTG
                     AKVQNKVNGTNYQSLDNKIATIYIPHKFKENKASIENTVVAEQFTGTNYTKDDLTVQV
                     IPDGQEFFYFNENGSSVPENKDNLPLESVTDSKD"
BASE COUNT          654 a          277 c          342 g          611 t
ORIGIN      
        1 tatttttaac aatctatcca atgagaacta atatgaaaaa ttggtgacaa aacattagtt
       61 ttgcttgctg taagcacttt aagttttgga tctgctgcta cagctagagt tgttagtgca
      121 gcaacagcgc atccagctcc atatccaatt attgatgaat ggaattatgg tgtaagtgat
      181 aactatggtt attctaatga ctatgttaag tctccaaata atattggttc aaaatcttca
      241 gtaactaatc tatggggaac agttaaggat agagattctc aaaaatatgg atgggcaaac
      301 tcaagcgcaa caaaaagctg gaatgatgtt cgattaaata cacattggaa ttactttaca
      361 ttttaaaaat ggtttatgaa agctaaaggc ccaataatgc tatagggcct tttatgatat
      421 aggtaggtgc ttatgaaatt aaaattatgc attgttggat tcttcttttg tttaattgct
      481 gccattggtc tggttagtat taatgatact caaaaaccaa tacctttacc aattgatggt
      541 gccttctcca ttcaagggaa aagcaatctt tctaatgaag aagtgtatca aacgattagt
      601 gacctatcaa aagagaaaaa agttaccatt tacaaaccgg tagttcaaaa ttcggggcag
      661 ttgacttata tcaagtttga taatactaat catgaacaat taaagtctgc accaatcaca
      721 gggatgtatt ataccctagg gaaattagat tcaaatagtt taaaaccgct cacatctaca
      781 ggtcttcaag tcatatatct ggcttaccct tggcagatag ggggaatgat acaatttact
      841 ggtccgttga gattattgct aatgatttca atttacttaa ccttattagt tgttctattt
      901 gttgttagag cgagacagat taaagaagga gtgataagac gttctttagg attacctgta
      961 cacgacctaa gaagagatta tttcatgtca tttacttttg aactggttat ggccgcttta
     1021 ttgatgattt cttatagttc ttttttgggt agtggttttt tcacctacag ttccaagtta
     1081 tttttttcta tgcttttaac taatttgatc atatttcaaa tcattgacat catcaccttt
     1141 gttctatttt ggctaactat taaggttgaa aaacctattg aaattataaa aaataaggcc
     1201 aaaaatagcc tcatttttat cgtatggctt gcggttattt ctatcataat agttgtttca
     1261 ggagtctttt tacgggaaac aaaggctagt caatcaaaga taaacatgca gataaagcat
     1321 ttaaaaccat ggagtgcagt aaaagattgg aaaagaccag agtttttggg tattgaaaat
     1381 gaatctgtta ctaatggaga agaagcaaat gactcaggag ctaagtacgt agagattgct
     1441 aaagccttaa aaaaactgga ttttatatat atcaaatcat cttcagccta tgttccagaa
     1501 tatatggcag cttctgatgt tacagaagat ttttctaagc aattaaaaag tgatggaata
     1561 acgcatccag aagttaataa ggaactggtt tatattaatc aaacaggtgc taaggtacaa
     1621 aataaagtta atggaacgaa ctatcaatca ttagataata aaatagcaac catctatatt
     1681 cctcataaat ttaaagagaa taaggcatca atcgagaata cagttgtagc agaacaattt
     1741 actggtacaa actatacaaa agatgacctt acggtgcaag tcattcctga tgggcaagaa
     1801 tttttctatt tcaatgaaaa tggtagtagt gttcctgaaa ataaagataa tctacctttg
     1861 gaaagtgtga cagatagtaa ggat
//
LOCUS       DARYXW010000147         1772 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.148, whole genome shotgun sequence.
ACCESSION   DARYXW010000147 DARYXW010000000
VERSION     DARYXW010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1772
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.148"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(207..1721)
                     /locus_tag="TV191_001886"
     CDS             complement(207..1721)
                     /locus_tag="TV191_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1508355.1"
                     /translation="MLDYYLERDIVERKLILAVLLTEKEITLDSLCSQTSITPRKAKE
                     YLNQINALFDKDLSITVLKSGITCEFDPNNKEKYFHSIYASSDTLKMLKFLLTDNYRT
                     KCLTTFIRRQFISKSKAYHLVNKLKGYLQSIHLDIDDYRVIGDEYRIRYLIAMLHKEY
                     GFAVYEMTPKDMEIIHAFIFLTPTRLKPTVFLDKKFYLFDILLMLSWKRQNYDVSLPQ
                     LTLFDRLKELSIFEQISCYAKQEIETRTQVVFNSGDLDYLYLVYLTVDSSFLMHYWND
                     KQLRLVYNILEEDPLYKELVNRLEMLFGRQLHLRDQMYFLLPFFRRCLFQLHDLISFQ
                     DYYSKRYQGSQLLLEKVEEQIKDWLMVSYQSETLSPGHLHFMCLHLEQMLELSLPPVE
                     VIIVENKRALGDVLSYFVISSIPSYKVNITRINMLTDSLENYEQAPDFVITSDNILPF
                     LEEQQVFPDKSVLIGMSMDYIKEQGKTVVKSILNFHRKHYEQLLEQLLIGDRVE"
BASE COUNT          607 a          365 c          290 g          510 t
ORIGIN      
        1 aaatccactt gaaaggctta tcacaagtgg atttttcaga aatattgtac caaataggca
       61 cgagctattg attgctgcta tttagcatag gtgttatcac gatcagcagt aagccaatca
      121 aaacaggtat cgctaaagca aatcctcaca aaaaatggtc caaagaaaaa cctagcagcc
      181 ttataccact tgcttagcaa aaaaacttac tctaccctat ctccaatcaa gagctgctct
      241 aaaagctgct cgtaatgctt acgatgaaag ttcagaattg attttaccac tgtttttccc
      301 tgctccttaa tgtaatccat gctcatacca attaagacgc tcttatctgg aaatacctgc
      361 tgctcctcaa gaaaaggcaa aatattatca ctcgtaatca caaaatcagg agcctgctca
      421 taattttcca gactatctgt tagcatgttg atacgagtaa tattaacctt ataagaagga
      481 atacttgaga taacaaagta agacaagaca tcacctaatg ctctcttgtt ttcaacgatg
      541 atgacctcta caggcggcaa ggacagctca agcatctgct ccaaatgaag gcacataaaa
      601 tgcaggtgcc ctggtgagag cgtttctgac tggtagctaa ccatcagcca gtccttgatt
      661 tgctcctcaa ccttttctag cagcagctga ctgccttgat acctctttga atagtaatcc
      721 tgaaagctaa tcaaatcatg caattgaaag agacatcttc tgaaaaaggg aagcaaaaaa
      781 tacatctgat cccttaaatg aagctgacga ccaaacaaca tttccaagcg attaacaagc
      841 tccttataca gcggatcttc ttctaagata ttgtagacaa gacgtaattg cttgtcattc
      901 caataatgca taagaaaaga actatcaact gtaagataaa ccaagtaaag ataatctaag
      961 tcaccagaat taaacacaac ctgagtacgt gtctcaattt cttgcttagc atagcaactg
     1021 atttgctcaa aaatagataa ttcttttaaa cgatcaaata aagtaagctg tggtaaggat
     1081 acatcataat tctgcctctt ccaagacagc atgagtaaaa tatcaaaaag ataaaatttc
     1141 ttgtccaaga aaacagtggg ctttaaccgc gtaggggtta aaaaaataaa ggcatgaata
     1201 atttccatat ccttaggtgt catctcataa acagcaaacc catactcctt atgaagcatg
     1261 gcaattaagt agcgaatccg gtactcatcc cctataaccc ggtaatcatc gatatccaaa
     1321 tgaatggatt gcaggtagcc ctttagctta ttgacaagat gataggcctt tgatttggaa
     1381 ataaactgtc ttctgatgaa agttgtcaga cactttgtcc tgtaattatc cgtcaacaga
     1441 aacttcaaca ttttaagcgt atcagatgat gcataaatac tgtgaaaata cttctccttg
     1501 ttattaggat caaactcaca ggtaatgcct gacttcaata cagtaataga caggtctttg
     1561 tcaaatagtg cattaatctg attaaggtat tccttagcct ttcgaggggt tattgacgtc
     1621 tgcgagcaca atgaatcaag tgtaatctct ttttctgtca ataagacagc caatattagt
     1681 tttcgctcaa caatatctct ttctaaatag taatctaaca aaataatctc tctccttatt
     1741 agtttgtatg accatataca ttttagttga ta
//
LOCUS       DARYXW010000148         1747 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.149, whole genome shotgun sequence.
ACCESSION   DARYXW010000148 DARYXW010000000
VERSION     DARYXW010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1747
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.149"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            <1..>1747
                     /locus_tag="TV191_001887"
     CDS             <1..>1747
                     /locus_tag="TV191_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="amino acid adenylation domain-containing
                     protein"
                     /protein_id="HEL1508356.1"
                     /translation="DISKKQGTSVYIAPVVFACNIDYPLETEFSRKNLGKVSYMISQT
                     PGVWLDFQTYIVDGDLILCWDSVDELFPTGMLEDMMDSLYELIISLTQKEEWEKKVDV
                     LPEKQKSIRMQDVEGILPLQYPSETLYDGFLRNVKLNPDRVAIIDSETKEEITYHKLY
                     EISLKVADCLGKNGVKKGDYVGITLPRGSRQLYAIFGILFTGAAYVSIGIAQPNDRRT
                     KIYDQIGIKCIISDEKTVIDCKLNKNEVKIIDLDVAMANVAKLKQPVEISPYDSAYII
                     MTSGTTGVPKGVEIMHTSAVNTCIDLNEKYNVNAEDTILMVSAIDFDLSVYDIFGILH
                     AGGTVITTSEDNYRNPDEWLNLVDEYKVTIWDSVPILFDMIVTMAEGKNRNLPFRIVM
                     LSGDWIAINLPERFYNISENINSIVVAMGGATEASIWSNHLNVPRKIPKDWISIPYGR
                     PLKNQVYRVVDEFGRICPNYVKGELLIGGVGVAKCYHGDEELTNKKYFEQDGMRWYRT
                     GDNGRTWNDGIIEFLGRKDTQVKVKGHRIELGEIENALIVFENIKKAIALIVKDGNVN
                     KLVGFAEIFDCKESN"
BASE COUNT          628 a          189 c          378 g          552 t
ORIGIN      
        1 gagatatatc aaaaaaacaa ggtacaagtg tgtatatagc acctgtggtt tttgcgtgta
       61 atatagatta tccattggaa actgaatttt caagaaaaaa tttagggaaa gtatcttata
      121 tgatttctca aacaccagga gtttggcttg attttcaaac atatattgta gatggagatt
      181 taattctttg ctgggatagc gtggatgaac tttttccaac aggaatgtta gaagacatga
      241 tggattcttt atatgaattg atcatatctt taacacagaa ggaagaatgg gaaaagaaag
      301 tagatgtttt acctgaaaag caaaagtcta ttagaatgca ggatgttgag ggaattttac
      361 cacttcaata tcctagcgaa acgttatatg acggatttct cagaaatgta aaactcaatc
      421 cagatagagt tgcgattata gattctgaaa cgaaggaaga gataacatat cataaacttt
      481 atgaaatctc tttaaaagtt gcggattgtt taggtaaaaa tggtgttaaa aagggagatt
      541 atgtaggaat aacacttcca agaggtagca gacaacttta tgctattttt gggattttat
      601 ttaccggtgc agcatatgta tcaattggta ttgctcagcc aaatgataga agaactaaaa
      661 tttatgatca aatcggaata aagtgcatta taagtgatga aaagacagtg atagattgta
      721 aattaaataa aaatgaagtt aaaattattg atttggatgt agctatggca aatgtggcta
      781 aattaaagca acctgttgaa attagccctt atgatagtgc gtatattatt atgacgtctg
      841 gaacaacagg tgttcctaag ggtgttgaga ttatgcatac aagtgccgtt aatacttgca
      901 ttgatttaaa tgaaaaatac aatgtaaatg ctgaagatac aatactgatg gtgtcggcaa
      961 tagactttga tttgtcggtt tatgatattt ttggaatact tcatgctgga ggaacggtta
     1021 ttacaacaag tgaagataat tatagaaatc ctgatgaatg gttaaattta gtcgatgaat
     1081 ataaggttac aatatgggat tctgtgccga ttttgtttga tatgattgtt actatggctg
     1141 aaggtaaaaa tagaaactta ccttttagaa ttgtgatgct ttcaggggat tggattgcta
     1201 taaatttacc agaaagattc tataatatta gtgaaaatat aaattctatt gttgtcgcta
     1261 tgggtggagc cacagaagca tctatttggt caaaccattt gaatgtacca agaaaaatac
     1321 cgaaagattg gatttccatt ccatatggta gacctttgaa aaatcaagtg tatagagttg
     1381 tggatgaatt tggtaggatc tgccctaatt atgttaaagg tgaacttctt atcggtggag
     1441 ttggtgttgc taaatgttat catggtgacg aagaattaac gaataaaaag tacttcgaac
     1501 aagatgggat gaggtggtat agaactggag ataatggtag aacatggaat gatgggatta
     1561 ttgagtttct tggaagaaaa gatactcagg taaaagttaa aggacataga atagaacttg
     1621 gagaaataga gaatgcttta attgtatttg aaaatataaa aaaagcgatc gctttaattg
     1681 ttaaagatgg aaatgttaat aaacttgtag gatttgcgga aatatttgat tgcaaagaaa
     1741 gtaatca
//
LOCUS       DARYXW010000149         1723 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.150, whole genome shotgun sequence.
ACCESSION   DARYXW010000149 DARYXW010000000
VERSION     DARYXW010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1723)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1723)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1723
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.150"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(640..1506)
                     /locus_tag="TV191_001888"
     CDS             complement(640..1506)
                     /locus_tag="TV191_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="HEL1508357.1"
                     /translation="MQYMGEMFKLLRTSRHISLKEATGDDFSHSMLSRFENGESDITI
                     SKLLVGLSNIRTELNEFIYLANGFKPSPYAVLKQEIWEAISKKDLSSLHQLYTKELEQ
                     YHLYKKDIYFLNALMIKSQMLFLDENIKMTPDEQSFLYDYLFSVEIWGIYELQLFSDI
                     SPLLSLDVYLRYTREMLGRVDFFEELWQHRNLVHSILLNGLFKATQEKRLGIAAYFDK
                     MINNHFFEENDTYLRIVYMIADGQHLYCKGEKELGLKQINDAIHILKALNCDESAAYY
                     SDSLEKWLKEVE"
BASE COUNT          536 a          339 c          241 g          607 t
ORIGIN      
        1 aaaattgctt tatagttttg aaatgttcct gaaatatgaa ttttaaatcc atattcaggt
       61 aaaacataat cattcgtctc tacatatcta aagcttgtca gatccatatg cttcaccatg
      121 taccagctga ataaatgggt acttctctgg atgctccatg attgtcttaa ctttcttttc
      181 cacgtaggct tcaaagcttt tttcaaagct acttgaacac tcacgagaat cttctttata
      241 gatacatttt taagtaatca ttggttttct catagcaata catctcctca gtcttattag
      301 tataaaacta aaaacgctca cattaacagg tctttttgag cgtttttagt aggactagtt
      361 actaaattat ggtttgtaga ttggacattt ccaagtcaca acaaagcctt tcactggcgc
      421 aaagcatcta ctagcctcgt atgcaaattg agtcatgttt gtgatctcct ttcattcttg
      481 atgagtctag tgtatcatca aaaaccgtac caaagctaaa ctgttcatat gttcaaatca
      541 tggttttgac attaatcaaa aaacagtagc tcaaaaagcc actgtttgct actagctaag
      601 catctaaacc attttgctta tcaatgcttt aagttgcatt tattcaactt cctttaacca
      661 tttctctaaa ctatctgaat aataggctgc actttcatca caatttaatg cctttaagat
      721 gtgtatggcg tcatttattt gctttaagcc tagttccttt tcccctttac aatataggtg
      781 ctgaccatca gcaatcatat aaacaattct taagtaggtg tcattttctt caaaaaaatg
      841 attgttaatc attttatcaa aatatgcagc tatacctagc cttttttcct gagtagcttt
      901 aaacagccca tttaataaaa tgctgtgcac taaatttcga tgctgccaaa gctcctcaaa
      961 aaagtctact cttcctagca tttctcgagt ataccgcaaa tacacatcca aggataataa
     1021 gggagaaata tctgaaaata attgtaattc gtatattccc caaatctcca ctgaaaacaa
     1081 ataatcatat aaaaagcttt gctcatctgg agtcattttg atattctcgt ctaaaaagag
     1141 catttggctt ttaatcatca aagcatttaa aaaatagata tcctttttgt ataaatgata
     1201 ctgctccagc tcttttgtat acaattgatg taagctggac aggtcttttt ttgatatggc
     1261 ctcccagatc tcttgcttta ggacagcata tggggaaggc ttaaagccat ttgctagata
     1321 gataaattca ttgagctctg tccgaatatt gctaagtcca accaatagct ttgagattgt
     1381 tatatcggat tcaccatttt caaatctgct taacatcgag tgagaaaagt catctcccgt
     1441 cgcttccttt aacgatatgt gtcgcgatgt ccgcagtaat ttaaacattt ctcccatata
     1501 ttgcatatca atacctcttc aatctttcat tttagtatag tatataacct taaaaatgta
     1561 aatccagtct tgattgcata aacctttaat tcaacgtttg atgctactaa atatcctatt
     1621 tttctgaagt agatcctcat ctttatgcta taagcacttg ctgcgtttta gaaaatgggc
     1681 taaatcagct atactccttt ttaataacaa aaaagcctta ttt
//
LOCUS       DARYXW010000150         1721 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.151, whole genome shotgun sequence.
ACCESSION   DARYXW010000150 DARYXW010000000
VERSION     DARYXW010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1721)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1721)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1721
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.151"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            13..381
                     /locus_tag="TV191_001889"
     CDS             13..381
                     /locus_tag="TV191_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HEL1508358.1"
                     /translation="MANRTRNNGIYLMLSDDELEILNKKYELSGCKSLRQFIMKCILE
                     KDIFVLDMKVFKEMSTNIGRITGSINQIAKRVNSTAVIYKDDINDLKKLLEKQGKDIY
                     FLRKKLYELGNFGTSGTEEI"
     gene            381..>1721
                     /locus_tag="TV191_001890"
     CDS             381..>1721
                     /locus_tag="TV191_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEL1508359.1"
                     /translation="MAVTKIHPIEKTLYLALDYIMNEDKTDEKILISSFGCNPKTAHL
                     EFEHTKKECNSKAKILARHLIQAFAPGETTPEQAHQIGLDLCERVLRGKYEYVLTTHI
                     DKGHLHNHILFNNVSFETGKAYQSNKRSYHQIRTVSDDLCRENGLSVIDENYKKFKNR
                     YSTNGKTYMEYTEFKKGNSWKNKLQLTIDKAVLKSKTYEEFLKTMEDFGYEIKIGKYL
                     SFRHKDKRDKGRFTRAKASTLGEDYTKERIKERIEDSNKQNIYVNQEYHYEKRSYKKP
                     DTIVDMKNNEKVKSSKGYEVWAGKHNMKTMASALNEMRKSGINSYEELDLKLKKVASD
                     RQQLLDHIKQIEKEMKSIYSVIENKNTISENQLTYDMYIKDKENKAFYEEYKSQIIAY
                     ETAMKSLKNSKLQTLSIKNLSDKYMLLEQEKTTLMGEYSSQNSMLRKLQQAKKNT"
BASE COUNT          726 a          248 c          300 g          447 t
ORIGIN      
        1 ggaggttata ctatggcaaa cagaacaaga aataatggaa tataccttat gctttctgat
       61 gatgaacttg aaattttgaa taaaaaatat gaactgtccg gttgtaaaag tttaagacag
      121 tttattatga agtgcatcct tgaaaaagat atttttgtac tggatatgaa agtgtttaag
      181 gagatgtcta caaatatcgg aaggattaca ggtagcatca atcagattgc aaaaagggta
      241 aattcaactg ctgtaattta caaagatgac atcaatgatt tgaaaaagct cttggaaaaa
      301 caaggaaaag acatctactt tcttcgtaaa aagctatatg aattagggaa ttttggaaca
      361 agtggtacgg aggaaatcta atggcagtta caaaaattca tccgatagaa aaaacacttt
      421 atctagcatt agactatatt atgaatgaag ataaaaccga tgaaaaaatc cttatctcct
      481 cttttggctg caatcccaaa acagcccatc ttgaatttga acatacaaaa aaagaatgta
      541 attccaaagc aaaaatcttg gcaaggcatc taattcaagc cttcgctcca ggagaaacta
      601 cacctgagca ggcacaccaa atcggactgg atctatgtga gagagtcttg aggggaaagt
      661 atgaatatgt ccttacaaca catatcgaca aggggcatct acacaatcat attctgttta
      721 acaatgtcag ctttgaaaca ggaaaggcat atcaaagtaa taagagaagt tatcatcaaa
      781 tccgaacggt cagtgatgat ttatgtagag aaaatggctt gtcagttatt gatgaaaact
      841 acaaaaaatt taaaaacaga tactctacaa atggtaaaac ctatatggaa tataccgaat
      901 ttaagaaagg aaactcttgg aagaataaac tacaacttac tattgataaa gctgttttaa
      961 aatccaaaac ttacgaggaa tttctaaaga caatggagga tttcggttat gaaatcaaaa
     1021 taggaaaata cctttccttc cgacataaag ataaaagaga taagggaaga tttaccagag
     1081 cgaaagcatc tactttaggg gaagattata caaaagagag aatcaaggaa cgaatcgaag
     1141 attcaaataa gcaaaatatt tatgttaatc aggaatatca ttatgaaaaa cgctcctaca
     1201 agaaaccgga tactattgta gatatgaaaa acaatgaaaa ggtaaaatca tctaagggat
     1261 atgaagtatg ggcaggtaaa cataatatga aaactatggc atctgcctta aatgaaatga
     1321 gaaaatcagg tattaactcc tacgaggaat tagatttaaa attaaagaaa gtggcatcag
     1381 atagacaaca attattggat catataaagc aaatagaaaa agaaatgaag tccatttatt
     1441 ctgtaataga aaataaaaat acgatttctg aaaatcaact aacctatgat atgtatataa
     1501 aagataagga aaacaaagcc ttttatgaag aatataaatc acagatcatc gcctatgaaa
     1561 cagctatgaa aagtcttaaa aattcaaagc ttcaaacatt gagcattaaa aatttatctg
     1621 ataaatatat gcttttagaa caagaaaaaa ctacacttat gggagaatat tcctctcaaa
     1681 actctatgct tcgcaagctg caacaagcaa agaaaaatac a
//
LOCUS       DARYXW010000151         1717 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.152, whole genome shotgun sequence.
ACCESSION   DARYXW010000151 DARYXW010000000
VERSION     DARYXW010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1717)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1717)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1717
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.152"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(72..>1717)
                     /locus_tag="TV191_001891"
     CDS             complement(72..>1717)
                     /locus_tag="TV191_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEL1508360.1"
                     /translation="ENKNLWLGTDFFEVPRESLRNKLINGIQSFSYLELVGTSKDKNN
                     KSPRKRSDAMADSLIQISIVPQQAKNTGKTWTDNWTSDGFLRWAVSLNFVSVDRETDM
                     FSITSKGLHFSRAIINSEEETAILRKALLSYPPATQILSLLADSGTYCTKYYLGEQLG
                     FRGEKGFTSYNEDIMFDWLGSATKSEKKLIKADIEGTSDKYARGICNWLKNVGLVDSQ
                     TIKRTFTNGEKDGFQGYKINGRGLHALRQAQGDSKHSKLEKFVMWEFFATHGNNREYV
                     RTRRAYIVKFLQETNSLAILLDKLRAKGFYDELEIILSDIQGLNYFGLRIDISSNRVS
                     LKDKINDFSIPELEITQELKDEQAEKRKAKFLKETNLPMKYIELLDIAYDGKRNRDFE
                     IVTMELFRNVYRLHSKLLGGGRKPDGLLYQDRFGVIVDTKAYGKGYSKSINQADEMIR
                     YIEDNKRRDENRNPIKWWEAFPDTIPQEEFYFMWVSSKFIGKFQEQLDYTSNETQIKG
                     AALNVEQLLLGADLVLKGQLHISDLPSYFQNKEIEFVKA"
BASE COUNT          556 a          355 c          230 g          576 t
ORIGIN      
        1 gaagatagca ttgaagtatt gattaccaat tataaaccaa atccaaaata ataaaagcat
       61 agttgaatta gctatgcttt tacaaattca atttctttat tttgaaaata agatggtaaa
      121 tcggaaatat gcagttgtcc tttaagaacc aaatctgctc ccaaaagcaa ttgctctaca
      181 ttgagggctg ctcccttaat ttgtgtttca ttagaggtat aatcaagctg ctcttgaaat
      241 tttccaatga atttacttga cacccacata aaataaaact cttcttgtgg aatcgtatct
      301 ggaaaagctt cccaccactt tatcggatta cgattttcat ctcgtcgctt attatcctca
      361 atataccgaa tcatttcatc agcctgattg atagatttag aataaccttt tccataagcc
      421 tttgtatcta caatcacacc aaaacgatct tgatagagta aaccatctgg ctttctgcca
      481 ccacctaaaa gcttagaatg caatctatat acatttctaa ataattccat tgtaacaatt
      541 tcaaaatctc gatttcgctt accatcgtaa gcaatatcaa gcaattcaat atatttcatt
      601 ggtaaattag tctcttttaa aaattttgcc ttacgctttt ctgcctgctc atcctttaat
      661 tcttgtgtaa tttctagttc aggaatagaa aaatcgttga tcttatcctt caaagaaact
      721 ctattgctag aaatatctat cctcaaacca aaataattca atccttgaat atctgataag
      781 ataatctcca gttcatcgta aaaaccctta gcccttagtt tatctaatag aatagccaaa
      841 gaattagttt cttggagaaa cttgacgata taagctctcc gagtacgaac atactcgcga
      901 ttattgccat gagttgcaaa aaattcccac atcacaaatt tttcaagctt gctatgctta
      961 gaatccccct gagcttgtcg taaagcatga agaccacgac cattaatttt ataaccttga
     1021 aatccatctt tttcaccatt agtaaaggta cgcttaatcg tttgtgaatc aaccaaacca
     1081 acatttttta gccaattaca aataccgcgt gcatatttat cacttgttcc ttctatatca
     1141 gctttaataa gttttttctc tgatttagtg gcagatccta accaatcaaa cataatatct
     1201 tcattatagg aagtaaagcc tttttcacca cgaaaaccaa gctgctcacc taaataatat
     1261 ttagtacaat aagtaccgct atcagccaat aaagataaga tttgtgtagc tggcgggtat
     1321 gacaacagtg cctttcttaa aatagcagtt tcttcttccg aattaattat tgccctagaa
     1381 aaatgcaacc ccttcgaagt aattgaaaac atatccgttt ctctatctac cgacacaaaa
     1441 ttcaggctaa cagcccatct taaaaaacca tctgatgtcc aattatccgt ccaagtttta
     1501 cctgtatttt ttgcctgttg aggtacgatg ctgatttgaa tcaaagaatc tgccattgca
     1561 tctgaacgct ttcggggaga tttgttattc ttatcctttg atgttccaac taattctaaa
     1621 tatgaaaatg attgaatccc attaatcagt ttgtttctga gtgattctcg tggtacttca
     1681 aagaaatctg tacccaacca taagttctta ttttcat
//
LOCUS       DARYXW010000152         1622 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.153, whole genome shotgun sequence.
ACCESSION   DARYXW010000152 DARYXW010000000
VERSION     DARYXW010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1622)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1622)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1622
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.153"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            161..1285
                     /locus_tag="TV191_001892"
     CDS             161..1285
                     /locus_tag="TV191_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HEL1508361.1"
                     /translation="MAKKEMKFYLRKSAFGLASVSAALLVGAAAVSADSVESAGPVAV
                     AVTDSLDSEAAATKAEADLVAAKADLAAAEVAITAAKAEFDTAQADLATAEATIAELE
                     QKIPELEKKIQEAQEKLNYENRPSPKRVGSDDEDDTVARKLMSEKEALKAELQKTKEA
                     LDTAKRAYAGIEERKQVAATKLDAANKAFAGVEEKHAQAMAAFGAAFAAYKEAVKAEL
                     KAAGASDFYTKKIDSADTVDGVKTLREMILDSIAKPEVEPEAKPEPKPEPKPEPKPEP
                     KPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPKPQPKPAPAPKPEAKKEEKKAAPK
                     QDTNKLPSTGEATNPFFTAAALAVMAGAGVAAVSTRRKEN"
     gene            complement(1447..>1622)
                     /locus_tag="TV191_001893"
     CDS             complement(1447..>1622)
                     /locus_tag="TV191_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="TetR family transcriptional regulator C-terminal
                     domain-containing protein"
                     /protein_id="HEL1508362.1"
                     /translation="SNLMNCAESQDYPEVTQKYVFELYIASIEVIIIKWISCGCKDSP
                     QQIIEILKLLRSK"
BASE COUNT          581 a          336 c          359 g          346 t
ORIGIN      
        1 gctaaagtaa tggttgacat ataattgtaa aaaaacagaa ataaaaaaaa aacggtttaa
       61 tattgaccta attggcaata acgtttacaa taaaggtata attatctgcc gttgataatt
      121 aggagacatc atgtctagat aaaaacaaaa ggggaataaa atggcaaaaa aagaaatgaa
      181 gttttacctt cgtaaatcag cctttgggct agcttcagta tcagcagccc tcttggttgg
      241 tgcggcagct gtatcagcag attctgttga gtcagctggg cctgtagcag ttgctgttac
      301 agatagttta gatagtgaag ccgcagctac aaaggcagaa gctgatctag ttgctgcaaa
      361 agcagaccta gcagcagcag aagtagcaat cacagctgca aaagctgaat ttgacaccgc
      421 tcaagcagac ctagctaccg ctgaagctac tatcgcagag cttgagcaaa aaattcctga
      481 gttagagaaa aaaattcaag aagctcagga aaaactaaac tatgaaaatc gaccatcacc
      541 taaacgtgtg ggcagtgatg atgaagatga cacagtagct agaaagctta tgtcagaaaa
      601 ggaagctctt aaggctgagc ttcaaaagac taaagaagcg ctagatacag ctaaaagagc
      661 ttatgctggc atcgaagaaa gaaaacaagt agcagcaact aagctagatg cagctaacaa
      721 ggcttttgct ggagttgaag aaaagcatgc tcaagcaatg gctgcatttg gagcagcatt
      781 cgcagcatac aaggaagctg ttaaggctga attgaaggca gcaggtgcta gcgacttcta
      841 caccaagaag attgactctg ccgacacagt tgacggtgtt aagacactca gagaaatgat
      901 cttagactca attgctaagc cagaggttga accagaggct aagcctgaac ctaagccaga
      961 accaaaacct gagccaaaac ctgagccaaa accagaacct aagccagaac caaaacctga
     1021 gcctaagcca gagccaaaac cagaacctaa gcctgagcct aagccagaac caaaaccaga
     1081 acctaagcca aaacctcaac ctaaaccagc tccagctcca aaacctgaag ctaagaagga
     1141 agagaagaaa gcagcgccta agcaagacac caacaaattg ccatcaacag gtgaagctac
     1201 aaatccattc ttcaccgcgg cagctcttgc agttatggca ggtgcaggcg tggctgcagt
     1261 gtcaacaaga cgcaaagaaa actaagcctt ataccccagt ggtaaagctt gagcgagaac
     1321 aatttgttct cgctttttta gtgtcttaaa agcacctaca gcaatcatag gtgcttaaca
     1381 agatatgtct aacgattgct atcagctgta gagaataaaa aggagagact aagccttgct
     1441 cacaagctac ttagaccgaa ggagctttag gatttctatg atttgctgag gggagtcctt
     1501 acagccgcag ctgatccact taatgatgat gacctcaata gaggcaatgt atagctcaaa
     1561 aacatatttt tgggtaactt caggataatc ttgtgattct gcacaattca tgaggttgga
     1621 at
//
LOCUS       DARYXW010000153         1615 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.154, whole genome shotgun sequence.
ACCESSION   DARYXW010000153 DARYXW010000000
VERSION     DARYXW010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1615
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.154"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(<1..902)
                     /locus_tag="TV191_001894"
     CDS             complement(<1..902)
                     /locus_tag="TV191_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004819958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEL1508363.1"
                     /translation="MSKLEEAKNILNELKVPPKQQSDLCGYVILAMADIKKNDEWANA
                     TNKWIRIHDVIAFIREFYEVSYAENSRETFRKQAMHHFRNAAFIEDNGKATNSPNYRY
                     RLTDEMLLLVKTFQSSLWEEQKNNFLKSHQNLIDLYSSKKAVRKMPVKINGDDFTFSP
                     GKHNQLQKFIIEEFAPRFAENSECLYVGDTIQKDLVKNEEKLKELGFEITLHDKMPDV
                     VLYSEDKNWIYFVESVTSVGAMEPKRIKEIEEMTENVSAGKIYVTAFLDFKTFKKFSE
                     SLAWETEVWIADMPDHMIHLNGDK"
     gene            complement(895..>1615)
                     /locus_tag="TV191_001895"
     CDS             complement(895..>1615)
                     /locus_tag="TV191_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DNA methyltransferase"
                     /protein_id="HEL1508364.1"
                     /translation="TTNDNFDFGSKTVFEASYDMVVSGEHKYVFLITDKEEADTIKKV
                     NEWNDTLPTLGLKMKTGLTVDFRNQEALRNDAEEKAVPLFYSQHIKDGKVIFPVGKEN
                     EYLLTEKKGLLQENTNYLFVKRFTAKEEKRRLQCGIYLAKKFPTYKAISTQNKINFIT
                     GLQGLSDCLVYGLYVVLNSTLYDNYYRILNGSTQVNATEINSMPIPPLTCIEDMGKEL
                     IKLKDMSEENCDEILGRFIYV"
BASE COUNT          496 a          324 c          193 g          602 t
ORIGIN      
        1 aatttatcac catttaaatg aatcatatgg tcaggcatat ccgcaatcca tacttccgtt
       61 tcccaagcta aagactctga gaatttttta aatgttttaa agtctaaaaa tgctgttaca
      121 tatattttcc cagctgaaac attttccgtc atttcttcaa tttcttttat tcgctttggc
      181 tccattgcac ccacagaagt tacagactca acaaagtaga tccagttctt atcttctgaa
      241 tataaaacaa catccggcat tttatcatgg agtgttatct caaagccgag ttcttttagt
      301 ttctcctcat tcttcaccaa atccttttga attgtgtcac caacatacaa acattcagag
      361 ttctcagcga atcgtggagc aaattcttca ataataaatt tctgtaattg attgtgtttg
      421 ccgggagaaa atgtaaaatc atctccgttt attttaacag gcatttttct taccgccttt
      481 ttagagctat atagatcaat taagttctga tgagatttta agaaattatt cttctgttct
      541 tcccacagac ttgattgaaa tgtttttact aataacaaca tttcatcagt taatcgatac
      601 ctgtaattag ggctatttgt tgctttccca ttatcttcaa taaatgctgc attcctaaaa
      661 tgatgcattg cctgtttacg gaatgtttct ctactattct ctgcatatga aacctcataa
      721 aactctctaa taaaggcaat aacatcatga attcttatcc atttattagt tgcattagcc
      781 cattcatcat tctttttaat atctgccatt gccaaaataa catatccaca tagatccgac
      841 tgctgttttg gtggaacttt caactcattc aaaatattct ttgcttcttc taatttagac
      901 atatataaat ctccctaata tttcatcaca attttcttca gacatatcct ttaatttaat
      961 cagttccttt cccatatcct caatacaagt tagtggtgga attggcatcg agttaatttc
     1021 agtagcatta acttgagttg atccatttaa aattctgtaa taattatcat aaagcgtaga
     1081 gttcaataca acatacaaac cataaaccaa acaatctgat aatccttgta agcctgtaat
     1141 aaaatttatc ttattctgtg tgctaattgc cttatatgtt ggaaattttt tagctaaata
     1201 aattccacat tgtaatctac gcttttcttc ctttgccgta aatcttttca caaataaata
     1261 attagtgttc tcctgcaata atcctttttt ctccgttaat agatactcat tttcttttcc
     1321 aacaggaaaa atcactttac catcttttat atgttgcgaa taaaataaag gaactgcttt
     1381 ttcctctgca tcatttctta aagcctcttg atttctaaaa tcaactgtca aaccagtttt
     1441 cattttcaag ccaagagttg gcaaggtatc attccattca tttacctttt taatcgtatc
     1501 agcttcttct ttatcagtta tcaaaaaaac atatttgtgt tctccggaaa caaccatatc
     1561 gtaagaagct tcaaaaacag tcttgctgcc gaaatcaaaa ttatcattcg ttgta
//
LOCUS       DARYXW010000154         1608 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.155, whole genome shotgun sequence.
ACCESSION   DARYXW010000154 DARYXW010000000
VERSION     DARYXW010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1608
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.155"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            91..648
                     /gene="efp"
                     /locus_tag="TV191_001896"
     CDS             91..648
                     /gene="efp"
                     /locus_tag="TV191_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEL1508365.1"
                     /translation="MIEASKLRAGMTFEAEGKLIRVLEASHHKPGKGNTIMRMKLRDV
                     RTGSTFDTTYRPDEKFEQAIIETVPAQYLYKMDETAYFMNTETYDQYEIPVANVEQEL
                     LYILENSDVKIQFYGTEVIGVQVPTTVELTVTETQPSIKGATVTGSGKPATLETGLVV
                     NVPDFIEVGQKLIINTAEGTYVSRA"
     gene            691..1080
                     /locus_tag="TV191_001897"
     CDS             691..1080
                     /locus_tag="TV191_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL1508366.1"
                     /translation="MTTENIGEIVISPRVLEVITGIATMQVEGVHSLHNKNMADTFNK
                     ASLGKGVYLQTEENGTVNADIYVYLQYGVKVPAVSMAIQRAVKSAVYDMAEVTISYVN
                     IHVEGIVPEKTPKPEMKSLFDEDFLDD"
     gene            1073..1525
                     /gene="nusB"
                     /locus_tag="TV191_001898"
     CDS             1073..1525
                     /gene="nusB"
                     /locus_tag="TV191_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEL1508367.1"
                     /translation="MTKHFQHSRRDLRERAFQALFAMEMGGDFLPASQFAYDYDKEAA
                     DDKQPSELPVFLLNLVNGVMDHKAELDEVIKKNLKTSWSIERLTVVDKTMLRLGLFEM
                     TLFEETPDRVALNEIIEIAKKYSDDTSAKFINGLLSQFVSDESAAVTE"
BASE COUNT          483 a          289 c          375 g          461 t
ORIGIN      
        1 aagggctgat aatggtcata aaacatttga gcctacagct cttttgtggt aaaataagac
       61 gataactatt ttagtaagag gtaataacaa atgattgaag caagcaagct tagagcaggt
      121 atgacgtttg aagcagaagg aaagctaatt cgcgtacttg aagcaagcca tcataagcca
      181 ggtaagggaa acactatcat gcgtatgaaa ttgcgtgatg ttcgtactgg ctctacattc
      241 gacacaacct atcgtccaga cgaaaagttt gaacaggcta ttatcgaaac agtgccggct
      301 caataccttt acaagatgga cgagactgct tactttatga atactgaaac ctatgaccag
      361 tatgagattc cagtagccaa tgttgagcaa gagctattat atatccttga aaactctgat
      421 gtgaaaatcc agttttatgg aacagaggtg atcggagttc aggtaccgac tactgttgag
      481 ttgactgtta cagagaccca gccatcaatc aagggagcaa ctgttacagg ctctggtaag
      541 cctgcaaccc ttgaaacagg actcgtggta aacgttccag actttattga ggtaggacaa
      601 aagctaatca tcaatactgc tgaggggact tacgtttctc gcgcttaatt cgctttccgg
      661 aattagtcta agagaaagaa aggaaatgct atgacaactg aaaatatcgg tgaaattgtt
      721 atttcgccac gagttcttga ggttattacg ggaattgcta cgatgcaggt cgagggtgtt
      781 cactcgcttc acaataaaaa catggcagat acctttaata aagctagtct tggtaagggc
      841 gtctatcttc agacggaaga aaatggaaca gtcaatgcag acatctatgt ttacctgcaa
      901 tatggtgtaa aggttcctgc ggtgtcaatg gctattcaaa gggctgttaa gtcagctgtt
      961 tatgacatgg ctgaggttac catttcttat gttaatatcc atgttgaggg gattgttcct
     1021 gaaaagacac caaagccaga aatgaaatca ttgtttgatg aggatttttt ggatgactaa
     1081 gcattttcaa cattcgagaa gagatttgcg tgagcgtgct tttcaagctt tatttgctat
     1141 ggagatgggc ggagattttc tgcctgcctc acagtttgcc tatgactatg acaaggaagc
     1201 agctgatgac aagcagcctt ctgagcttcc tgtttttctg ttaaatcttg tcaatggcgt
     1261 tatggatcat aaggctgagc ttgatgaggt tatcaagaaa aaccttaaaa cgagctggtc
     1321 cattgagcgc ttgacagtgg tagacaagac gatgttgcgt cttgggctct ttgagatgac
     1381 cctgtttgag gagacacctg atcgtgtagc cttaaatgaa atcattgaaa ttgctaaaaa
     1441 atattctgat gatacctcag ctaagtttat taatggctta ctcagtcagt ttgtttctga
     1501 tgagtcagct gcagtgacag aataacaagc tggtgaaagc ttcttaagtt actaaagccc
     1561 tatagggctt tttgaatgct caaaaacgtc tcatctggtt ggctatgt
//
LOCUS       DARYXW010000155         1594 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.156, whole genome shotgun sequence.
ACCESSION   DARYXW010000155 DARYXW010000000
VERSION     DARYXW010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1594)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1594)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1594
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.156"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            1..1594
                     /locus_tag="TV191_001899"
                     /pseudo
     CDS             1..1594
                     /locus_tag="TV191_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893534.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="Dam family site-specific
                     DNA-(adenine-N6)-methyltransferase"
BASE COUNT          603 a          283 c          221 g          487 t
ORIGIN      
        1 agatccaatt gattatctac aaaggcttaa tggtaaaatt ggatattaca caaaaaatta
       61 ctctcctcta ggagattgta tgtatctaac acaagaaaat actgaaaaaa ttgataatat
      121 cagacagatc atagaagatt ggaacaacaa tcaattactc acagagtacg aatattttta
      181 ccttttaaat gctttgatag aagctattcc ttatgttagt aatattactg gaacctatgg
      241 cgcttttctc aagcattggg acaaccgagc gttgcattcc ttaacattag cagaagagac
      301 tatttttgat aattatcgtc ctaacaaagc gtttaatgaa aatgctaatg aattagtcaa
      361 aaaaataaaa gcagatattg tttacattga taccccctac aatgctcgac aatacgcatc
      421 aaattatcat ttactcgaaa acatcgcccg acatcaaaag ccaattttaa aagggattac
      481 taaaattttt gattggaaaa ctcttaaaag tgattattca acaaaaacaa aggctttaaa
      541 agcaatggaa gatttaattg ctaatattaa tgctagtcat atcattctaa gttacaatac
      601 cgagggtatt atatccgaag aagatttaac acttttactt caacgatatt cgttcaataa
      661 tcaaattgat gtgaaacgga ttccttaccg aaaatatcaa tctaagaaaa aatctcagaa
      721 caaagactta tacgaacttc ttttttatat tcaaagaaag ccgataaata atcgcttcaa
      781 atcacaaact aaaaaaaagg cagccatcat cagtcaaaaa aagtatataa aaagcccatt
      841 aaattatatc ggtggaaaat atcgactgct aaatcaaatc attccaattt ttccccgaca
      901 tatcaataca tttgttgata tgtttagtgg ggggcaaacg ttggtatcaa tgttcctgct
      961 aaaaaacaca tctttaatga tatgaactat cgcattaatg acatgtttcg atattttcaa
     1021 tcacatgacc cacttgagat acttgaacaa attgagcatc gaatttcaga atatcaactc
     1081 agcaagacca atgaacaagg ctttttaaca ttccgaaaac attataatac tcatccaaat
     1141 ccactagact tatacgtact atcgtcttat agctataact atcaatttcg ctttaataac
     1201 tcaatggaat tcaataaccc attcggcaga aatagaagtc attttagtga aaatatgaaa
     1261 tccaatctac tcaattttgt agctcgacta caccgtttag atgccacttt ctctgatcaa
     1321 tttttctcag attttgatat ttctacatta tcaatagatg attttgttta tcttgatccc
     1381 ccctacctca taacgactgg cagctataat gatggaaatc gtggcttcac aaactggggc
     1441 gaaaaacaag aaattgaaat gtatcaatta ataagagacc ttaacaagaa acaaattaag
     1501 gttgcactta gtaatgttct tgttcataaa ggaaagcaca atgatttact tgagcaattt
     1561 gttcaagatg aaagtctata tctcaccact ttaa
//
LOCUS       DARYXW010000156         1591 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.157, whole genome shotgun sequence.
ACCESSION   DARYXW010000156 DARYXW010000000
VERSION     DARYXW010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1591)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1591)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1591
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.157"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            60..>1591
                     /locus_tag="TV191_001900"
     CDS             60..>1591
                     /locus_tag="TV191_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HEL1508368.1"
                     /translation="MNIELKENLEKNYDDNVWEHVTLGEFVANCAETYKDKTAIVDGE
                     LNLSYDELDKLSNKYANGLLKAGFKKGDKIVLQLPNCYEFIVISFAMFKTGIIPIMSL
                     PAHRKNELKGIIEKSEAVAYISKDKYLGFSYVDMVRDMKSELNTNLEIYILGESEEYK
                     NFSSLIENDCFYKYPDVDYRSIGLLLLSGGTTGIPKLIPRRHCDYIYVAKKTTDRCNV
                     NQESVYLASLPIAHNFPLGCPGIMGTFAKGGKVVLCNVTSPDEILPLIEEEKVTITGF
                     VPAIANICMDYLEYEEYDLSSLEVIQVGGSVLEPWLAEKIEKVFDVKLQQIFGIAEGL
                     ILTTNEEDNDKIRWQTQGKPISEHDEILIVDEQGKIVGIEEYGELIVRGPYTIYGYYN
                     LPEVNETCITQDCYFKTGDKARKLKDGNYQIVGRIKEIINRAGEKITPLELEEILLTH
                     ENINSVQVVGLPDRLQGESIAVFILNGDKELTLEEVRKFLISNNVADFKLPDTVKYID
                     AWP"
BASE COUNT          564 a          190 c          347 g          490 t
ORIGIN      
        1 ttgatagcat tcagcatttc atcgaaatat tttggagcaa tttgcatata ggaggaagta
       61 tgaatataga attgaaagaa aatttagaaa aaaattatga tgacaatgtt tgggaacatg
      121 tgaccttggg agagtttgtt gcgaactgtg cggaaacgta taaagataaa acagcgattg
      181 tagatggaga attaaactta tcttatgatg agcttgataa actttcgaat aagtatgcta
      241 atggactact taaagcaggt tttaaaaaag gagataagat tgtattacag cttccaaatt
      301 gttatgaatt tatagtgata tcttttgcaa tgtttaaaac aggaattatt ccgattatga
      361 gtttgcctgc acatcgaaag aatgaattaa agggtattat agaaaagtct gaggcggtag
      421 catatatttc aaaggataaa tatttaggtt tttcatatgt ggatatggtt cgggatatga
      481 aatctgaatt aaatacgaac ttggagattt atattcttgg agaaagtgaa gaatataaaa
      541 atttttcgtc acttattgag aatgattgtt tctataaata tccggatgtc gattacagga
      601 gcataggatt attgttatta tctggcggta caacaggaat accgaaactg attccaagaa
      661 gacattgcga ttatatctat gttgcaaaga aaacgacgga ccggtgtaac gtaaatcagg
      721 aaagtgtata tcttgcttct ttgccaatag ctcataattt tcctttgggg tgtccaggga
      781 taatgggtac ttttgcaaaa ggcggaaagg tggttttgtg caatgtgaca agccctgatg
      841 aaattttacc tttaattgag gaagaaaagg ttacgataac aggatttgtt cctgcaattg
      901 ccaatatttg tatggattat ttagagtatg aagagtatga tctttcctct ttggaggtta
      961 tacaagtcgg aggttcagtt ttggaacctt ggttggcaga aaaaattgaa aaagtttttg
     1021 atgttaaact acaacagatt ttcggaatcg ctgaaggatt gatcttgaca acaaatgaag
     1081 aagataacga taaaataaga tggcaaacac aaggcaaacc aatcagtgaa catgatgaaa
     1141 tactgattgt ggatgaacaa ggaaaaattg tagggattga agaatatgga gaacttatcg
     1201 ttagaggtcc ttataccatt tatggttatt ataatcttcc tgaagtaaat gaaacatgta
     1261 taacacaaga ttgttatttt aagactggtg ataaagcacg aaaactaaaa gatggtaatt
     1321 atcaaattgt cggaaggatc aaagaaatca tcaatagagc aggtgaaaag ataacaccac
     1381 ttgaattaga agaaattttg cttactcatg aaaatatcaa ctcggtacaa gttgtagggc
     1441 tgccagatcg tctgcaagga gaatccattg ctgtatttat tttaaatgga gataaggagc
     1501 ttacactgga agaagttaga aaattcttga tttctaataa tgtggcggat tttaaattgc
     1561 cggatactgt taaatatatt gatgcgtggc c
//
LOCUS       DARYXW010000157         1574 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.158, whole genome shotgun sequence.
ACCESSION   DARYXW010000157 DARYXW010000000
VERSION     DARYXW010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1574)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1574)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1574
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.158"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(58..600)
                     /locus_tag="TV191_001901"
     CDS             complement(58..600)
                     /locus_tag="TV191_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PH domain-containing protein"
                     /protein_id="HEL1508369.1"
                     /translation="MNLDTVLQQMKECGAYDTWGTKKEVKALPEILSDDEIIQYATSG
                     FVNGNTVLVVLTQKRILFIDKGMLYGIRSTEIPLDMVNSVSYSKGLILGAIAVMNGAT
                     KIEISNIAKDTCPVLTEKIKDCVEQYKYNLYQHQSPQKTATVGSEDAVAEIRKFKKLY
                     DEGILTEEEFIAKKKIILGI"
     gene            complement(626..1411)
                     /locus_tag="TV191_001902"
     CDS             complement(626..1411)
                     /locus_tag="TV191_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1508370.1"
                     /translation="MNDKELALYIGSKIKELRKNKGLTQKELAILVNMGDTTIANYEK
                     GFRTPKKNTLFKLANALSVTIDELFPPINKKNKENIVHLKQQSNTTEINNKVALLDKE
                     LKEPRHSYWVKYGENLLSEQNTVGHSKNTVEEPQAAYYTYNYYDHAASAGTGQYLSDV
                     QVETIELPVDYDADFVIPVYGDSMEPEYHSGDYVFVKLSVELTDGDIGVFEYYGDAYI
                     KQLLINDEGAFLHSLNSKYEDIPVDRDSDFRIIGEVVGSYSEK"
BASE COUNT          462 a          293 c          247 g          572 t
ORIGIN      
        1 tcgccaaagt ttgagagcgt ggggcttttt ttatttttta acggttaact ttacacctta
       61 aattcctaaa attatttttt tcttagctat aaactcttcc tctgtaagaa tgccttcatc
      121 ataaagtttt ttaaacttac ggatttcagc aacggcatct tccgagccta cagttgctgt
      181 tttctgaggc gattgatgtt ggtacagatt atatttgtat tgttctacac aatcttttat
      241 tttttcggta agtacagggc aagtgtcctt ggcaatatta gatatttcaa tttttgtggc
      301 tccgttcata acagctattg cgccaagaat taaaccttta gagtatgaga cgctattaac
      361 catatcaaga ggaatttctg tcgatctaat tccatataac attcccttat cgataaataa
      421 aattcgtttt tgggtcaata caacaaggac agtattgccg tttacaaacc cagatgttgc
      481 gtattggata atttcgtcat ctgacaaaat ttctggcaaa gcctttactt ctttctttgt
      541 cccccaagtg tcgtaagccc cacattcctt catttgttgc aaaacagtat ctaaattcat
      601 aataaaactc cttataaaaa tattcttatt tttcagaata actccccaca acttcaccaa
      661 taattctaaa gtcgctatct ctatctacgg gtatatcttc atacttgcta tttaaactgt
      721 gcagaaatgc cccctcgtca tttataagta gctgtttgat ataagcgtca ccataatact
      781 caaaaacgcc tatatcgcca tctgttagct ctacggatag cttaacaaag acatagtccc
      841 cagagtgata ttcgggttcc atggaatctc cataaacagg aataacaaaa tcagcgtcat
      901 aatcaactgg taattcaatt gtttctactt gcacatcact taaatattga ccagtaccag
      961 cagaagcagc gtggtcgtag tagttgtagg tgtagtaggc ggcttgtggt tcttctactg
     1021 tattcttact gtgtcctact gtgttttgtt cagataaaag attttcaccg tattttaccc
     1081 aataactatg acgaggttct ttgagctctt tgtctaataa agcgactttg ttattaattt
     1141 ctgtggtgtt agattgctgt ttaagatgta cgatattttc tttatttttt ttatttatag
     1201 gagggaagag ttcatctata gtaacagata gggcattcgc aagtttaaac aaagtatttt
     1261 ttttaggcgt tctaaacccc ttttcatagt tagcaattgt agtatccccc atattaacca
     1321 agattgctaa ctctttttga gttagccctt tattttttct cagttccttg attttagagc
     1381 cgatatataa agctagctct ttatcattca tttgaattct tctttctttt tatttaataa
     1441 tagtataaca cataaattca cgttttgaaa agtttttttg ttttttcgaa aaaaaacagt
     1501 tgacacttca cgaaaagtga agtacaatat aatcaagctt aaggaattaa gcaaaataaa
     1561 aactcccaag aggg
//
LOCUS       DARYXW010000158         1544 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.159, whole genome shotgun sequence.
ACCESSION   DARYXW010000158 DARYXW010000000
VERSION     DARYXW010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1544)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1544
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.159"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            80..1531
                     /locus_tag="TV191_001903"
     CDS             80..1531
                     /locus_tag="TV191_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014293901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA binding domain-containing protein"
                     /protein_id="HEL1508371.1"
                     /translation="MENKKDLIQTLAYYQFSLENQYLDRKSARKKPQELLKHLIAFAN
                     ADGGQLVIGIEDEKQDNIITGFKDGRAYPIDDFKKIDHEMRETPLDLSLEEIPVLNHK
                     GEDDLILVISVELSSNRVIAAPNDEVYLRQGDESVKLSYEQRTQLSYDKGQRFFEDEV
                     VPDATLEDIDDGLVQDFKNRFDISERSMEEVLKARRFLVNGKLTKAAILLFAKYPSAF
                     FPQARVRFQRFDGTDMGTGSSFNVIKEVTFDDALPTLIIKVRDFIRTQLREFQYLDDN
                     GQFQILPEYPEFAWFEGVVNAVTHRDYSVYGDHIRVLMFDDRLEIHSPGKLPNIVTVD
                     NIKHECFSRNPRIARTLTEFGWVREMNEGVKRIYSEMESAFLHEPKYLEPGNKVVLTL
                     ENNIVSRHLRTRDSLEKQFSDFGNLTADEQAIVHYMYNSGDKMTTAKAIELTGRSRSF
                     VVKMLHHLRDLEIITWFGSSKNDRNQYYLLVDK"
BASE COUNT          470 a          261 c          347 g          466 t
ORIGIN      
        1 ataaaaagct gacttataat ttatttggaa acgacagtta atcctaaaat acgatgcttg
       61 atatggagga ggcttaaact tggaaaataa aaaggattta attcaaacct tagcctacta
      121 ccaattctca ctagaaaacc aatacttgga tagaaaatca gcacgaaaga agccgcaaga
      181 attactcaag catctgattg cttttgccaa tgcggacggc ggtcagttgg ttattggtat
      241 tgaagatgag aagcaggaca atattatcac tggtttcaag gatggcagag cttatcccat
      301 agacgatttc aaaaaaattg accatgagat gcgggagact cctctggatt tgtctttaga
      361 ggaaatccct gtgctaaatc ataagggaga agatgacctg attttggtta tttctgttga
      421 attatcgtcg aaccgagtga ttgctgcgcc taatgatgag gtttatctgc gtcagggcga
      481 tgaatcggtt aaattaagct atgagcaacg tactcagctt agctatgata agggccaacg
      541 tttctttgaa gatgaagtgg tacctgatgc gaccttggaa gatattgatg atgggttagt
      601 ccaggacttc aaaaatcggt ttgatatttc agagcgctcc atggaagaag ttcttaaagc
      661 aagacgattc ttggttaatg gtaaattaac taaggcagcg attctactct ttgccaaata
      721 tccatcagcg ttttttccac aagctcgtgt tcgttttcaa cggtttgacg ggacggatat
      781 gggaacaggc agtagcttta atgttattaa agaagtaact tttgatgatg ctctgcccac
      841 cttaattatc aaagtgcgag attttatccg tactcagctg cgtgaatttc agtacttaga
      901 cgataatggg caattccaga ttttgcctga gtatcctgaa tttgcttggt ttgagggtgt
      961 tgtcaatgcg gtgactcacc gtgattactc tgtctatggg gatcacattc gtgtactcat
     1021 gtttgatgat agactggaga ttcatagccc agggaaatta ccaaatatcg ttaccgttga
     1081 caatatcaag catgaatgtt tttctagaaa tcctcggatt gcgagaaccc tgactgaatt
     1141 tggatgggtt cgtgagatga atgaaggagt gaagcgtatc tattctgaga tggaatcagc
     1201 ttttcttcat gaacctaaat atttagaacc aggtaataag gtagttttga cccttgaaaa
     1261 taacatcgtg agtcgacatc tccgaacacg agatagtttg gaaaaacaat tttctgattt
     1321 tggaaatctg actgcagatg aacaagctat cgttcactac atgtataatt ctggcgataa
     1381 aatgacaaca gcaaaggcga ttgagttgac agggagaagt cgttcgtttg ttgtcaaaat
     1441 gctacatcat cttcgtgatt tagaaatcat cacttggttt ggttcaagta aaaatgaccg
     1501 taatcaatat tatcttttag ttgataaatg attgcagcca ggat
//
LOCUS       DARYXW010000159         1503 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.160, whole genome shotgun sequence.
ACCESSION   DARYXW010000159 DARYXW010000000
VERSION     DARYXW010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1503
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.160"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            71..1468
                     /locus_tag="TV191_001904"
     CDS             71..1468
                     /locus_tag="TV191_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY family transposase"
                     /protein_id="HEL1508372.1"
                     /translation="MIESKKYLVIKAVCEGKKQKNRACVELGLSKRQVNRLILAYREK
                     GKSAFVHGNRSKRPTHAMSLETKRRIIEKYQSYGDLRPNVVHFCELLAEEENIAYSDT
                     TVRKLLYQAGFLSPKTQRATKRRLKQEAKQKKREAEKRGSKLPTASNFFEEPDKAHPS
                     RARKKFKGELIQMEASQFPWFGQQETHLHVAIDDASGDIVGAYFDTQETLNGYYHVLE
                     QILEVHGIPFQFLTDKRTVFTYASSQSKKIEEDTFTQFGYACHQLGIAIETSSIPQAK
                     GRVERLNQTLQSRLPIDLQRNQITSISQANRYLKRWIKRFNKQFGGLASESVFEKAPK
                     PAQRNLLLARISERVIDSGHHIRYQNNFYLPVEGDKKIYFTRKTKALVIEAFDGDIYL
                     NIADNIYATRKLPKHEKHSKEFEMVPKTKKERRKYIPPQSHPWKLASFKQYLHKIGKS
                     YEEFKRERNTSQPQL"
BASE COUNT          530 a          300 c          299 g          374 t
ORIGIN      
        1 gtcttagcta ggtcgaatgt gaaaatgtcc cgtctgttaa actagaaaga tgaggaaaat
       61 agaactaact atgatagagt caaagaaata cctagtcatc aaagctgttt gtgagggtaa
      121 aaaacagaaa aacagggctt gtgtagaatt agggttaagc aagaggcagg tgaaccgatt
      181 gatactagcc tatcgagaga aaggaaagtc agctttcgtt catggtaata gatcaaaaag
      241 accaactcat gccatgtctt tagaaacaaa gagaaggatt atcgagaaat atcaaagtta
      301 cggtgattta agaccaaatg ttgttcattt ctgcgaacta ctagcggaag aagaaaacat
      361 cgcctattca gatacaactg ttagaaaact actctaccaa gcagggtttc tatctccaaa
      421 gactcaacga gcaacgaaaa gacgattgaa acaagaagcc aaacaaaaga aaagggaggc
      481 agaaaaaaga ggatccaaac tcccaactgc ttccaacttc tttgaagaac ctgacaaagc
      541 tcatcccagc cgagcaagaa agaaattcaa aggggaactc attcaaatgg aggccagtca
      601 attcccttgg tttggacaac aggaaacaca tcttcatgtc gctattgacg atgcctccgg
      661 tgatattgtc ggggcttact ttgatactca ggagacgcta aacgggtatt atcatgtctt
      721 agaacagatt ctagaggtac atggtatccc tttccagttc cttactgata aaaggactgt
      781 attcacttat gcttccagtc agtctaaaaa gatcgaggaa gataccttta cacagtttgg
      841 atatgcttgc catcagcttg gtattgccat tgaaacgtct tctatccctc aagctaaagg
      901 gcgtgtagaa cgtcttaatc agacccttca atcgcgtcta ccaattgatt tacagaggaa
      961 tcaaattacc agcatctctc aagcgaatcg ttatcttaag agatggatta aacgatttaa
     1021 caagcagttt ggtggactgg ccagtgagtc tgtttttgag aaagcaccta aaccggccca
     1081 gcgaaaccta ctgttagcga gaatctctga aagagtaatt gatagtgggc atcatattcg
     1141 atatcaaaac aacttctact tgcccgtcga aggggataaa aaaatctatt ttacgcgtaa
     1201 gacaaaggca cttgtgattg aggcattcga tggagacatc taccttaata tcgcagacaa
     1261 tatttatgcc actagaaagt taccaaaaca cgagaagcac tccaaagaat tcgaaatggt
     1321 gcctaaaact aaaaaagaaa gacgcaagta tattccacca caatcccatc cgtggaaact
     1381 tgcatctttc aaacaatacc ttcataaaat cggaaaatct tatgaagaat tcaagcgtga
     1441 gaggaatacc tctcaaccac aattataaca gatttttctc ttatctaacc gattttttca
     1501 aga
//
LOCUS       DARYXW010000160         1428 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.161, whole genome shotgun sequence.
ACCESSION   DARYXW010000160 DARYXW010000000
VERSION     DARYXW010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1428)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1428)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1428
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.161"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            85..1344
                     /locus_tag="TV191_001905"
                     /pseudo
     CDS             85..1344
                     /locus_tag="TV191_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          440 a          342 c          265 g          381 t
ORIGIN      
        1 gggttatagg gctttatgag tatcaaaaaa gtcccatatg acctataatg aaaagcgact
       61 aaactatcat ttagaaagac tcatatggaa caatcacatg ttatcacaca actactggga
      121 attaaagacc ctcatatcac attctccaaa gaaatacacg acatgaaaac tcataaggaa
      181 ttgaaagctg tccttgacta cgatgcccca ccttgcccta actgccaaag tcagatgggc
      241 aagtacgact tccaacggga atccaaggtc ccttttctcg attgcgcagg ctacaagact
      301 ttgattcgcc tcaaaaagcg ccgtttcaaa tgtcagtttt gcggaaaaat tactgtcgct
      361 gagacttctc tagtccctaa aaaccatcaa ataccaacca tcgtcaaaca gaaggtggcc
      421 cagcttctca tcgagaaagt ctccatgacc gctatcgctg atagactatc catctccacc
      481 tcaaccgtca tgcgaaagct caacgagttc acgttcaagt ctcatttgac ttatttaccc
      541 gaacatatgt cctgggatga atatgccttt aagaagggca agatgagctt tattgctcag
      601 gactttgaca ccaacaacat catcgctatt ttggatggac ggacgaaagc tgtcattcgc
      661 aaccacttcc tgagatatcc tcggcaggtc agaaacgacg ttaaactcat caccatggat
      721 atgtttaccc cctattacaa cctggctaag atgcttttcc caaacgctta gattgtcctt
      781 gatcgtttcc acattgtgca acatttggga cgtgccatga accgtatccg tactcaaatc
      841 atgaactctt ttgatcgaaa atcccacgaa tacaaggctt tgaaacgtta ctggaagctg
      901 attcaacaag atagtagcaa acttagtgac aagcgttttt accgcccgac ttttcgcatg
      961 catttgacaa acaaggaggt ggtcgagcgt cttttgagct actctgacga gcttagaaag
     1021 cattatgacc tttatcagct tctgcttttt cacttccagg aaaagcaagc tgaccacttt
     1081 ttcggcctga ttgaggagca gatagacagt agcaatcctc tctttcagac cgttttcaag
     1141 acctttttga aagacagaga caagattgag aacgcactgg atttgcctta ttctaacgct
     1201 aaactggagg ctaccaataa tctcatcaaa gtcatcaagc gcaatgcttt tggatttcgg
     1261 aactttgaaa actttaaaag acggattttg atcgctatca atattaaaaa agagaagacc
     1321 aatttggtcc tctccagatg ttagcttgtc aactacccac tacagttgac atggagccgt
     1381 tagttattag tcaacccact acagctgaca aaaaatccaa atagtccg
//
LOCUS       DARYXW010000161         1404 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.162, whole genome shotgun sequence.
ACCESSION   DARYXW010000161 DARYXW010000000
VERSION     DARYXW010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1404)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1404)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1404
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.162"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(33..1391)
                     /locus_tag="TV191_001906"
     CDS             complement(33..1391)
                     /locus_tag="TV191_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anion permease"
                     /protein_id="HEL1508373.1"
                     /translation="MILKSGIRNNHIKWIFTMLPLFVSVLPFISNIEKVFILILISIF
                     LLASNIIPAWYTSILFMTACMIGNIAEKQVILSGITSGAAWLVISGVIIGAAVKHTEL
                     DRLLARFFIPVCMGKYSKVLFGTILLGVVLIFLMPSAMGRVVLLLPILNALSLELGYE
                     KGSKEWEGIVMSGVLATYIPAFYVLPSNVPNNVFTGAILSLYSINISYSRYFLLYFPI
                     LGVGKILILYFTMRLFYRRCKDSICVSKKAIDITKEQKLLIVLLFITLSFWMTEHIHK
                     VPTGWTGMATALIVMLPNSNFMEKQPLRKINFEPFFYVAGIISLGNIAKSSGLANVIA
                     VHLINIVSLETASAFNVLTFFVVLCIILGFIVTLPGVPAVVTPLIDNISGVSNVSKTF
                     LCHIEVIGFSSVFFPFQAPPLMVVLQNENLSKARMTIYCSIVSAIGLLLLLPLALYWK
                     ML"
BASE COUNT          526 a          260 c          184 g          434 t
ORIGIN      
        1 atagtacgag gatataatta aatcttcgtc ttttacaaca ttttccaata taacgctagt
       61 ggtaacaaca ataataatcc aatagctgat acaatcgaac aatatattgt cattcttgct
      121 tttgataaat tttcattttg taaaaccacc atcaagggtg gtgcctgaaa tgggaaaaat
      181 acacttgaaa aacctataac ttcaatatga cataaaaatg tttttgaaac attactaacg
      241 cctgaaatat tatcaatcaa aggtgtaact actgccggaa cacccggtaa agttactata
      301 aatcctaata taatacacaa tacaacgaaa aaagttaaaa cattaaatgc acttgctgtt
      361 tccaaagaaa caatattgat taaatgcaca gcaatgacat ttgcaagtcc tgaagatttt
      421 gctatattcc ctaaacttat gattccagct acataaaaaa atggctcaaa atttattttt
      481 cttaaaggtt gcttttccat aaaatttgaa tttggtaaca ttacaatcaa ggcagttgcc
      541 attcctgtcc aaccggttgg tactttatga atatgttctg tcatccagaa agacagagtt
      601 ataaataaca aaactattaa caatttctgc tcttttgtta tgtcaatggc ttttttggac
      661 acgcaaatcg aatctttaca tcttctataa aataaccgca ttgtaaaata taaaatcaat
      721 atttttccaa ctcctaaaat agggaagtac aagagaaagt atctgctata ggatatattt
      781 atggagtaaa gacttaaaat tgctccagta aaaacattat ttggaacatt ggaaggtaat
      841 acataaaatg caggtatata ggttgctaaa acccctgaca taacaattcc ttcccattcc
      901 ttacttcctt tttcataacc taattctaaa gatagggcat ttagaatagg taaaagcaaa
      961 actactctac ccattgctga tggcatcaaa aaaattagta ccactcctag caaaatcgtc
     1021 ccaaataaca ctttagaata tttccccatg cacaccggaa taaaaaatct cgcaagtaat
     1081 ctatcaagtt cagtatgctt tactgccgcc cctataataa cacctgaaat aacaagccat
     1141 gctgcacctg aagttatccc tgataagatg acttgcttct cagctatatt ccctatcata
     1201 caagctgtca taaataaaat gcttgtatac catgcaggaa ttatattgct tgccaaaagg
     1261 aagatagata taagaatcaa aataaaaact ttctctatat ttgaaataaa tggtagtaca
     1321 gatacaaaca acggtaacat tgtaaatatc cactttatat gattattcct aattccagat
     1381 tttaaaatca tcctccattt ttga
//
LOCUS       DARYXW010000162         1383 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.163, whole genome shotgun sequence.
ACCESSION   DARYXW010000162 DARYXW010000000
VERSION     DARYXW010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1383)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1383)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1383
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.163"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(<1..176)
                     /locus_tag="TV191_001907"
     CDS             complement(<1..176)
                     /locus_tag="TV191_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL1508374.1"
                     /translation="MTFLDDIKQGCLDGWTKYKILPSLTAAQAILESGWGKYAPHNAL
                     FGIKADSSWTGKSF"
     gene            complement(293..664)
                     /locus_tag="TV191_001908"
     CDS             complement(293..664)
                     /locus_tag="TV191_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HEL1508375.1"
                     /translation="MFIFLRQLIQTQDGKILFTLGAIAVAMMIDFLTGTVAAKINPNI
                     DFRSKEGINGILRKICSIALMIFFIPLSILLPNDTGVAFLYVMYVGYLLFELKSILEN
                     LNKMGIDVALFKQFIDMFSKK"
     gene            complement(676..1287)
                     /locus_tag="TV191_001909"
     CDS             complement(676..1287)
                     /locus_tag="TV191_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HEL1508376.1"
                     /translation="MRNWKVTGKYPQFDSTGAVASTHVIITAEDGSVISQPIKQDLTS
                     TNDTEIIKATLEEFKKSEYVEIAMGEAVQKVDDLEKLSQETAKTATTAQAAAGLAKVS
                     AERTQKMINLQTIHMLTSVDKIEPDIYKGMLELIEPAKKGQYQEHDVFTVLDDKHEDL
                     AGEGNLVFVYVNEAFTYDKQTLKDLESEDKVTVIKYADLVKGK"
     gene            complement(1291..>1383)
                     /locus_tag="TV191_001910"
     CDS             complement(1291..>1383)
                     /locus_tag="TV191_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEL1508377.1"
                     /translation="LAEAEDEFTGAEIILIDNILEQYEANKKGE"
BASE COUNT          362 a          314 c          266 g          441 t
ORIGIN      
        1 ttaaatgact tacccgtcca agagctatct gccttgatac caaatagagc gttatgtggg
       61 gcgtacttgc cccaaccact ctcaaggatt gcctgtgctg cggtcaacga tggcaagatt
      121 ttatactttg tccagccatc taagcagcct tgcttaatgt catctaaaaa ggtcatctgt
      181 cctccttatc taaaaacgga taaacaatca gagcaatcac agacagcggc acatatagca
      241 ctgcgattgc taggactatt gctaatcgtg tgattgctcg catgagatcc tcctattttt
      301 tactaaacat atcaataaat tgcttaaaca gtgcgacatc aatccccatt ttgtttagat
      361 tttctaagat tgattttagc tcaaagagca gatagccaac gtacatgaca tacaaaaagg
      421 ctactcctgt atcatttggc agtaaaatcg acaaagggat aaaaaagatc atcagggcaa
      481 ttgagcaaat tttgcgcaaa ataccattaa tcccctcttt gctcctaaaa tcaatgttgg
      541 ggttaatttt tgctgcaacg gtacccgtta aaaaatcaat catcattgcg actgcaattg
      601 ctcctaaagt aaataggatt ttaccatctt gggtctggat taattgtctc aaaaaaataa
      661 acatggatca cctcactatt tgcctttaac caaatcagcg tatttaatca ctgtgacttt
      721 atcctctgat tccagatctt tgagggtttg cttgtcatag gtaaaggcct cattgacata
      781 cacaaagaca agattgccct caccggccaa atcctcgtgc ttgtcgtcta gcacagtaaa
      841 aacgtcgtgc tcctgatact gacctttttt ggctggctcg ataagctcta gcatgccttt
      901 gtaaatgtca ggctcgatct tatcgacgct ggtcaacatg tggatagttt gcaagttaat
      961 catcttttgc gtgcgctctg cggacacttt agccagacca gctgccgctt gtgcagttgt
     1021 tgctgtctta gcagtttcct gcgatagttt ttccaagtcg tccacttttt gcaccgcttc
     1081 gcccatggcg atttccacgt attcggattt tttaaattct tccaaggtag ctttgatgat
     1141 ctctgtgtca ttagttgagg ttaagtcctg cttgattggt tgagagatga ctgagccatc
     1201 ctctgctgta ataataacgt gagtgcttgc gactgctcct gtgctgtcaa attgtgggta
     1261 ttttcctgtg actttccaat tgcgcataat ttactctcct tttttatttg cttcgtactg
     1321 ctctaaaatg ttgtcgatta agatgatttc ggcccctgta aactcatctt cggcctcggc
     1381 caa
//
LOCUS       DARYXW010000163         1366 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.164, whole genome shotgun sequence.
ACCESSION   DARYXW010000163 DARYXW010000000
VERSION     DARYXW010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1366
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.164"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(<1..395)
                     /gene="mreD"
                     /locus_tag="TV191_001911"
     CDS             complement(<1..395)
                     /gene="mreD"
                     /locus_tag="TV191_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEL1508378.1"
                     /translation="MKKSSELLVLLPFLLFFVDAHVSDLISSMLPEGYSVVSHLFLLF
                     FLILMVAFRSKGVICFFSLLLGLLFDYYYFDHIGILSLALPFGTMIVLGLLRFFSGSI
                     SQLQFFLFFTLYMFLVDVSSFILANSYQLT"
     gene            complement(398..1213)
                     /locus_tag="TV191_001912"
     CDS             complement(398..1213)
                     /locus_tag="TV191_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEL1508379.1"
                     /translation="MKKLNLSRLFFWLTSLALLALTLVLLFRVAISPYLSMIIRNPVT
                     KIDAIMSKPFAVIKEGAKELDSLMSAFSENKHLKKELRSYKLDQLQVDKLKSENRELK
                     ELLGLDYGTDNQFAARMISRNPYSWNKSLVIDSGKREIKEKSLVTSELGLIGRVTAVS
                     QSSAHVELLTSGKNIELPIKIVDKDKVIYGNLKAFKSESKTMVASEFNSNDSISLDAK
                     VYTSGLDGETVADIPVGKVTGFKNAADKLKRRIFIKLYADTDNLDYVLVVGKE"
     gene            complement(1272..1359)
                     /locus_tag="TV191_001913"
     tRNA            complement(1272..1359)
                     /locus_tag="TV191_001913"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1323..1325),aa:Ser,seq:gct)
BASE COUNT          510 a          278 c          200 g          378 t
ORIGIN      
        1 gttaactgat agctgtttgc caaaataaag cttgatacat ctacaagaaa catataaaga
       61 gtaaagaaaa ggaaaaattg tagctgacta atggaaccag aaaagaacct taatagccct
      121 agaacgatca ttgttccaaa aggcaaggca agagacaaaa tccctatatg atcaaaataa
      181 taataatcaa acaataatcc taaaagaaga gagaagaaac aaataactcc cttagatcta
      241 aacgctacca taaggatcag gaaaaacagt aaaaagaggt gtgatactac cgagtaaccc
      301 tcaggtaaca ttgagctgat caggtctgac acgtgtgcat caacaaaaaa taaaagaaaa
      361 ggcaaaagga ctaatagctc tgaagatttt ttcatattca ctcttttcca acaacaagaa
      421 catagtcaag attatcagta tcagcataca attttataaa aatacgacgc tttagcttat
      481 cagcagcatt tttaaagccc gtaacctttc caacaggaat atctgccaca gtctcaccat
      541 ctaatccact tgtataaacc ttagcatcta atgatattga gtcattagaa ttaaattcgc
      601 tggcaaccat tgttttactt tctgatttaa atgcctttaa attgccataa atcaccttat
      661 ccttatctac aattttaatc ggcaactcaa tattcttccc agatgttaac aattcaacat
      721 gagcagatga ctggctaaca gctgtaacac gaccaataag tccaagctct gaagtaacca
      781 aagacttctc cttaatttcc cttttgccgc tatcaatgac cagcgattta ttccagctat
      841 aaggatttct tgatatcatt ctggcagcaa attgattatc agtaccataa tccaacccta
      901 acagttcctt gagctctcga ttttcagatt ttagcttgtc aacctgtaac tgatccaatt
      961 tataggacct aagttccttt tttaaatgct tattttcaga aaaagcagac atcaagctat
     1021 ctaattcctt tgcaccctcc tttataacag caaaaggctt agacattata gcatcaattt
     1081 ttgtaacggg atttcggata atcattgata aatatggaga aatagctact ctaaaaagaa
     1141 gaaccaaggt caaagccagt aaagctaatg atgttaacca aaaaaagaga cgagataggt
     1201 taagcttttt caataaaatc acctctaaaa ataaaaaaac gattatcagt atgataatca
     1261 cctttacaat acggagaata agggattcga acccttgcgc cagttacccg acctaacgat
     1321 ttagcaaacc gtcctcttca gcctcttgag taattctcca aataat
//
LOCUS       DARYXW010000164         1336 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.165, whole genome shotgun sequence.
ACCESSION   DARYXW010000164 DARYXW010000000
VERSION     DARYXW010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1336
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.165"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            <1..1147
                     /locus_tag="TV191_001914"
     CDS             <1..1147
                     /locus_tag="TV191_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEL1508380.1"
                     /translation="EKYDQTTLENMGENEKQVGIKADKEAISKFTSLTLNGKKYTDKK
                     QAGEFLINKIKGIKKLDDFRSEEVKIGEYRNFDLFAYYDRFSNQYKFNLKGEENHYGE
                     FGTDEIGNITRMDNVLDRMPERLEQTLGKLKDTENQLETAKLEIKKKFPQAELLKEKT
                     LRLAEVNNLLDMGQKGDLKEEKNPLLEEVKEELIHFLNKEYDEAHSIEDFDTMFPDLT
                     DIGLAYTTTPDEKHEIQTSLDLINYKMNTYVDNTLIDSFQYTYDPLNASDTKELIQIK
                     TNIGFWDFNELVYVDEEKLKASLGLEIDDDGNFYDPLSKDMDLDGVMDRYDADFRDSK
                     VQSFGDLDKKEKASVMDRLGYFKEKIKKGGLQNENIDRKIECKEEVR"
BASE COUNT          560 a          156 c          279 g          341 t
ORIGIN      
        1 agaaaaatat gatcagacta ctttagaaaa tatgggtgaa aatgaaaaac aagtggggat
       61 aaaagcagat aaagaagcaa tatcaaaatt cacatcttta actttaaatg ggaaaaaata
      121 taccgataaa aagcaagccg gagagttctt aataaacaag ataaaaggaa taaaaaaatt
      181 agatgatttt cgttctgagg aagtaaaaat cggagaatat agaaatttcg atttgttcgc
      241 atattatgac aggttctcca atcagtataa attcaatctg aagggagaag aaaatcatta
      301 tggggagttt ggaacggatg aaatcggaaa tatcacccga atggataatg tacttgatag
      361 gatgcctgag agattggagc agacacttgg aaaacttaaa gataccgaga atcaacttga
      421 aacggcgaag cttgaaataa aaaagaaatt tccacaggca gagcttttaa aagaaaagac
      481 gttaagactt gctgaggtaa ataatttgct tgatatggga caaaaaggag atttaaaaga
      541 ggagaaaaat ccacttttgg aagaagtgaa ggaagaactg attcattttc taaataaaga
      601 atatgatgaa gcacacagta tagaagattt cgatacaatg tttcctgact tgacagatat
      661 aggtttggca tatacgacta caccggatga aaagcatgag atacagacaa gtcttgattt
      721 aatcaattac aagatgaaca cttatgtaga caatacttta attgacagtt ttcagtatac
      781 ttacgatcca cttaatgcaa gtgatacgaa ggaacttata caaatcaaaa cgaacatagg
      841 tttttgggat tttaatgagc tggtatatgt ggatgaagaa aagttaaaag catcacttgg
      901 acttgaaatt gatgacgatg gtaatttcta tgatccgctt tcaaaggata tggatttaga
      961 tggagtaatg gacaggtatg atgcagactt tagagatagt aaagtacaaa gttttggaga
     1021 tttggataaa aaagaaaaag catccgtaat ggataggctt ggatacttca aagaaaagat
     1081 aaagaaagga ggcctacaaa atgaaaatat tgatagaaag atagagtgta aggaggaggt
     1141 tagatagttg gaatatcaca aaaatattag agcaacggat agagaaatgc agaaactttt
     1201 tgaaaatgag gagtataact attccgtaag atattttgaa aaaatagaag aaaacttatt
     1261 taaaacgata attcgcacac cggagaatat agagtttcca aaatccaaaa ccttgtctat
     1321 aaacacgata aaaaaa
//
LOCUS       DARYXW010000165         1324 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.166, whole genome shotgun sequence.
ACCESSION   DARYXW010000165 DARYXW010000000
VERSION     DARYXW010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1324)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1324)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1324
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.166"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(1011..1115)
                     /locus_tag="TV191_001915"
     CDS             complement(1011..1115)
                     /locus_tag="TV191_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019773529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL1508381.1"
                     /translation="MTAFEVVQILLGFSSFTIALISLCYQIFKDDNKK"
BASE COUNT          452 a          216 c          240 g          416 t
ORIGIN      
        1 taattaatta accagttaac tatatcaatc tatcaaaaaa aatatagtat gtcaacctct
       61 taaagtgatt taatcagaac aaacgtatga agaaaatcat ttggtgaaaa agaagcttat
      121 tttagctgaa atagatccat tataaaagag gtgtcgtgaa gtaactcaat attcacctat
      181 ttttgtcgca agtattctaa taggaataga aaaagggcag ttgcttgcaa caactaccca
      241 atgtaaaacc gttaaagacg gtgacagaaa ataactgtta actgaactac ctcaaaagtt
      301 aaaccaaaga tctaaccgtt ggatgttggt ttgtagagcg gttatttttt tattgttatg
      361 tttacaacga ctaagctcat cagtgtaagg gaaagggact tccatattaa gaagtatata
      421 tacatcctag atgagacgtg taatgaatgg gttgaacaaa tagttgctta attttgggat
      481 aagggttata ataaaaatag aaaaagggca gttgcttgca acaactaccc aatgcagaac
      541 cgtttgagac ggtggctggt tttatagtta aaagataacc gttaactcgc caaagttaag
      601 gacggttatt ttttattgtc atctttgaag atttgatagc acaagctgat aagcgcaata
      661 gtaaagctac taaagcctaa aaggatttat accacttcaa aagctgtcaa tgctttgact
      721 catcctttct gttagatttt gatgaactgc ccataggcct cacctacctt tcagaaataa
      781 gagccaccgt cttaaccttt ctgctttatc attatagcat attgttatta aggttgacta
      841 ttcagactcg tctaaagaag tgtaatagtt gcttaatttt gggataaggg ttataatgaa
      901 aatagaaaaa ggtagttgct cgacacaact acccatgcag aaccgtttaa gacggtggca
      961 tgttttatgt tattaaaaaa taaccgttaa ctcgccaaag ttaaagacgg ttatttttta
     1021 ttgtcatctt tgaagatttg atagcacaag ctgataagcg caatagtaaa gctactaaag
     1081 cctaaaagga tttgtaccac ttcaaaagct gtcaatgctt tggctcctcc tttctgttag
     1141 attgtgatga actgcccata ggcctcacct acctttcaga aataagagcc accgtcttaa
     1201 cttttctgcc tttttattat agcataccct atctctgatt gactagctta agaaggaggg
     1261 gatgtgattt ggatacaaat ttttgttaac ttttttaaag tctccaaatg atttaaaaaa
     1321 atga
//
LOCUS       DARYXW010000166         1317 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.167, whole genome shotgun sequence.
ACCESSION   DARYXW010000166 DARYXW010000000
VERSION     DARYXW010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1317
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.167"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            84..1283
                     /locus_tag="TV191_001916"
                     /pseudo
     CDS             84..1283
                     /locus_tag="TV191_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842898.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
BASE COUNT          496 a          258 c          187 g          376 t
ORIGIN      
        1 cattaacatt attcgtcata tttttacttt cattttcttt tcttggtcaa aaagaagtaa
       61 cggtatcgtc acgaggtgaa attatgccta caaaagtcat tgcatcaata cagtcaacta
      121 gcaacaatgc tatcgttaaa aataatctta aagaaaacca actcgttaaa aaaggaaaac
      181 gtttaatcaa atataaagaa accattgaga gttctcaaaa gaattctcta gaatcacaat
      241 taaatacgtt gaataaacaa aaagttggtt tagagacatt gaaagaaagt ctcaaacaag
      301 gaacgaacct cttaccacaa aatgatgaat ttggtcttgc tgacaccttc aacaacttta
      361 taaatcagtc tcaagagatt aaacttggta tcgctaaaat aaatacagaa gtatccaatc
      421 aatccacact tgcaaataac acccttgctg caattgatac tcaaatcaat actataaacc
      481 agcagatttc agaatatgaa gatcttcgtc aagctatctc aaatcataac acaatcttac
      541 caactggtaa tcctcatcaa gatattctca ataattatct gtctcaatca caagaagaat
      601 aaacttccac gtctaaccag tttatctctc agattaacca gactatttca ggtttagaat
      661 catccctctc tgggcttagc attcaaagag caggtactgg tagtagtgca acatacgata
      721 acagttcaga aaccaaagtt gaagtcttga ggactcaatt tctacagaat gcttcacaac
      781 agctgtcaac catcgacagt caaatcactg aacttaaagc tcagctagaa caagcaagtg
      841 tatagttaga cactaatgtt gttttagcac cagaaaccag gattattcat ctaaataatg
      901 aatacgaggg gaaaagtctt atcccaaatg gtagtgatat tgccaaaatc tatcctaata
      961 ttactcaaac tagaaaagct ctgattacat actttgtaac ttctgattat gtttctctcc
     1021 ttaaaaaagg tcaaactgtt cgtctaaatc ttcaaaaagt gagaaaacag tccatcactg
     1081 ttaatggaaa aatttctact attgataaaa cagcaacaaa aacagaacaa ggtaatcttt
     1141 tcaagattac aactcttgcc aaactccctt ccaaggatag ctacttgata aaatatggtg
     1201 cacagggtcg tgttacaagt gttatcgcta aaaaatccta cttcgacttt tataagaata
     1261 aactgttgtc aaatcatgat taaaccattc cggacgtttc gatgaccatt taggatt
//
LOCUS       DARYXW010000167         1316 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.168, whole genome shotgun sequence.
ACCESSION   DARYXW010000167 DARYXW010000000
VERSION     DARYXW010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1316
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.168"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(146..538)
                     /locus_tag="TV191_001917"
                     /pseudo
     CDS             complement(146..538)
                     /locus_tag="TV191_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
     gene            complement(535..1062)
                     /locus_tag="TV191_001918"
     CDS             complement(535..1062)
                     /locus_tag="TV191_001918"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEL1508382.1"
                     /translation="MIKKDYRQLVLQRLAMMTPEDKLEKDLALLAAVVASSSYQEAQT
                     LVTYLPLPHEYQSHLLIERALQDGKTILVPKTRSRGEMVFVAYDPCDLIQTAFGLMEP
                     RCTIAVAKSEIDAIHVPGLVFHPAGYRIGYGGGYYDRYLRDYQGATFSTIYACQWEDF
                     VVEAHDIAVKEVYCQ"
BASE COUNT          423 a          330 c          254 g          309 t
ORIGIN      
        1 ggtaaagcac tagaaagcac tcaacagcag acaaaatagg agttggggca accgtcctag
       61 aagcattaaa aagcaacagc agcaaaaccg ttgctttttg tttaaatcaa agatacacct
      121 gtcctagcac ttataagctt gaaggaaaaa gaccaaaaag agaggtggaa gcacctgctg
      181 ctacggtatc tggtgtcagc cacatgataa aagcattccc cataatccct gaacacacat
      241 acagcagcaa aaactgtctt gacccccaaa tggtctcagc catccgcccg acaaaataaa
      301 gggttaaggt attaatgaaa aaatgctcaa agccaatatg aaccactata ggtgtcacca
      361 agcgccaaag ctgatcaggc attgctctga caacaagacc attcatgcca ccaaatataa
      421 caacagcata agggtgcgta gcaaactggc catagaccag ctgcattatc aaaaaaacta
      481 aaccagtcaa gcccaagaaa aagagtgtta tcgggtattt tttgatcatc agtctcattg
      541 gcaatacacc tccttcacag caatatcatg tgcctctacc acaaaatcct cccactgaca
      601 ggcataaatc gtgctaaagg tagccccctg ataatccctc aaataacgat catagtagcc
      661 accaccatag cctatacgat agcctgcagg gtgaaaaaca agccctggca catgaatggc
      721 atcaatctcc gacttagcaa cagctatggt acacctaggc tccataagac caaaagccgt
      781 ctgtatcaag tcacaaggat cataagccac aaacaccatc tctccacgag aacgagtctt
      841 gggcacaagg atagtcttgc cgtcctgcaa ggctcgctca atcagtagat ggctttgata
      901 ctcgtgtggc aagggcagat aggtcacaag agtctgcgcc tcttgatagc tgctactagc
      961 aactactgct gccaatagag ctaagtcctt ttccagctta tcctctgggg tcatcatggc
     1021 taggcgctga agcactagtt ggcgataatc ttttttaatc atgcccatat cataacacaa
     1081 agcgctgcta ctattcaaga atcggccaca atcaaggttc tttccttagt tgtcctacca
     1141 gacagggcag cagctcaatc agtgaatgtc cttcttactt cttgaggtga gcttgtggtc
     1201 tcatgagatc aaaaaattat ttttctaggt taagaaaagt ttaagcttta tgctatacac
     1261 ccgactttat cacttgtttt agtccacacc ttactcaacc ccttggtaga gtaagg
//
LOCUS       DARYXW010000168         1301 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.169, whole genome shotgun sequence.
ACCESSION   DARYXW010000168 DARYXW010000000
VERSION     DARYXW010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1301
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.169"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            <1..>1301
                     /locus_tag="TV191_001919"
     CDS             <1..>1301
                     /locus_tag="TV191_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1508383.1"
                     /translation="KRQKKITKLGKSIDKQEKKLFFQKNMEEMKKSVDYQNTSRLRQF
                     FKRRQYKNQIQKKYKDSVKNRIKKSFIEGSKRFGEFVKGRGKKIIFLSLLAVGIFFML
                     FQAGSMMMNMGTGMVSNTVSTTYLSSEDTLKEINQRFSSLEQALQEEMDSVEENHPGY
                     DEYIIKGKEKIGHNVHELLSYITARYGIVKNISEVESELKHLFQKMYTLTYKEEIEIR
                     YRTVTSSYTDADGNEHTESHEEPYEYRKLIVTLEKREMDGIIREAFKRYPNNLAHYET
                     LFLTQGNMGEVFGNIDLINSNGGIGGGKEYEASSEVQKKIVNAAYITPSPGAGWCAMW
                     VSQVYQNAGLGFIGGNACDMYRNYTFTSDRSKLKVGMLVAVESSSSGSSLGVTYGHVG
                     IYIGDGKVMDNIGHIRVTTLDDWIATFCKHHPVGFGFPPSV"
BASE COUNT          491 a          165 c          287 g          358 t
ORIGIN      
        1 aaaaaggcaa aaaaagataa caaaattagg taaaagcatt gataaacagg agaagaaact
       61 cttttttcaa aagaatatgg aagagatgaa aaaaagcgtg gattaccaaa atacctcaag
      121 gctcagacaa ttctttaaga gaaggcaata taaaaatcag attcaaaaga agtataaaga
      181 tagtgtgaaa aacagaataa aaaaatcctt tatagagggc agtaaaagat ttggcgaatt
      241 tgtaaagggc agagggaaaa agataatatt tctatcactt ttagcggtag gaatattttt
      301 tatgttattt caggctggga gcatgatgat gaatatggga acgggaatgg taagtaatac
      361 tgtttcaacc acctacttat catcagaaga caccttaaaa gaaatcaatc agaggttttc
      421 atctttggaa caggctttgc aagaagaaat ggacagtgtg gaggaaaatc atccgggcta
      481 tgatgaatat attatcaaag gaaaagagaa aattggtcat aatgttcatg aactcttgtc
      541 atatatcaca gcccgttatg gaattgtaaa gaatatttct gaagtagaaa gtgaactaaa
      601 acatctgttt caaaaaatgt atacgctgac ttataaagaa gagattgaaa tcagatatag
      661 aactgttaca tccagctata cggatgctga tggcaatgaa catactgaaa gtcatgaaga
      721 gccgtatgag tataggaaac tcattgtaac cttagaaaaa agagagatgg acggaattat
      781 tagagaagca tttaagcgtt atcctaataa tttggcacac tatgaaactt tatttttgac
      841 acaaggaaat atgggagaag tatttggaaa tattgacctt ataaattcaa atggtggaat
      901 tggtggtggt aaagagtatg aagcatcaag tgaagtgcaa aagaaaatag tgaatgccgc
      961 ttatattaca ccatctccag gagcaggttg gtgtgccatg tgggtatcac aggtctatca
     1021 aaatgcagga cttggattta ttggaggaaa tgcttgtgat atgtatcgaa attatacttt
     1081 tacttctgat aggtcaaagt taaaggttgg aatgcttgtt gcagttgaaa gtagcagtag
     1141 tggtagcagt ttaggtgtta cctatggtca tgtaggtatt tatatcggag atggaaaagt
     1201 aatggataat atcggacaca taagagtaac taccctagat gattggattg caacattttg
     1261 caaacatcac cctgtaggtt ttggatttcc accatcagta c
//
LOCUS       DARYXW010000169         1279 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.170, whole genome shotgun sequence.
ACCESSION   DARYXW010000169 DARYXW010000000
VERSION     DARYXW010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1279)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1279)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1279
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.170"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(79..549)
                     /locus_tag="TV191_001920"
                     /pseudo
     CDS             complement(79..549)
                     /locus_tag="TV191_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            764..985
                     /locus_tag="TV191_001921"
     CDS             764..985
                     /locus_tag="TV191_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009568291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEL1508384.1"
                     /translation="MDTKFTALTEEQLKSVEGGKNGVVKLPGGTGVYCWNTGKNSAKC
                     GMDWSVAGPYVGKIIVNGWVNHGPWASRP"
     gene            1015..>1279
                     /locus_tag="TV191_001922"
     CDS             1015..>1279
                     /locus_tag="TV191_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL1508385.1"
                     /translation="MNERDLVQLIEQTLKDEEVQNNVTYRNLLEESLQQLSLKKPVYL
                     VSTRLAGHISTYLMTNHYEAPKAIIVLAQSIASTPAKHRGLISI"
BASE COUNT          422 a          215 c          248 g          394 t
ORIGIN      
        1 agaattatcg caaaattatg atagcgtcgc tgataaaatt cagcacttct aaacagattt
       61 ggattcatga atatctcctt acttactaaa taaatgatga tagaagcctt gatgcgtcat
      121 taattcgtta tgcgaaccta tctcgattat ttttccttta tcaagtacaa caatttggct
      181 agtacgttca gcagtactaa gacgatgggc aacgaaaata atcgttttct cggtcattga
      241 cattaggtta tcaatcactt ttttctccgt taagacatct agtccgcttg tcgcctcatc
      301 gagaattaga ataggagact tggttaataa tgctctagct aatgcaattc tctgtttttg
      361 tccaccagaa aatcctgccc catcagatag ttctgtctga tagcccatag gcatttgttc
      421 aatatcttct ctaatttctg ccatatcaca ggcattgata atatcctctt gagtaatcgc
      481 ttggtttgca ccgagagtaa gattttctaa aattgatcca ctaaaaatat aagcttgttg
      541 aggcagatat tggttatcga aacgtcctaa atggtaatct gacaaatcta tcaaattatc
      601 tcaaacggtt gaatttaagt cttaagcggt aaatttttcc catttaggac gtttcgatga
      661 ctgtttagga aatggagaac aaattttaac cgaaagtgtt atactaagtc tgtcaagctt
      721 gcaaccggac aaaataaaaa cacatataaa ggaggtattc gtcatggata caaaatttac
      781 agcgttgact gaagagcaat tgaaatcagt tgagggtgga aaaaatggag ttgtaaaatt
      841 acctggaggg accggtgtat attgttggaa tacaggaaaa aatagtgcaa aatgtggtat
      901 ggactggagt gtggcaggac catatgttgg taagataatt gtcaatggtt gggttaacca
      961 tggaccttgg gcaagtcgtc cataatttta atttatatag agaggtgtga aatcatgaat
     1021 gaaagagatt tagtacagct gatagaacag actctaaaag atgaagaggt gcaaaataat
     1081 gtcacttata ggaatctttt ggaagaaagt ctccagcaat tatcactcaa aaagcctgtg
     1141 tatttagtta gtaccaggtt agcaggacat atttcaacct atctaatgac aaatcattat
     1201 gaggcaccaa aagcgattat agttcttgct caatctatcg catcaacccc agctaaacat
     1261 agaggtttaa tttctatac
//
LOCUS       DARYXW010000170         1253 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.171, whole genome shotgun sequence.
ACCESSION   DARYXW010000170 DARYXW010000000
VERSION     DARYXW010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1253
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.171"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(32..1213)
                     /locus_tag="TV191_001923"
     CDS             complement(32..1213)
                     /locus_tag="TV191_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEL1508386.1"
                     /translation="MTKRLLLFVLVCLCFLGISQVHAEDVMEITRKAGYTVSEVNRPK
                     ASIVVDAKTSEILWQDNIDMPRDPASMSKMFTLYILFEELAKGKVTLDTTITATETDQ
                     AISKIYEISNNNIVAGVAYPIRDLIIMTVVPSSNAATVMIANYLSNNDASAFIDRINK
                     TAKELGMTNTHFSNASGAIAQAFQGYYLPEKYDLTASNITTARDFATLIYYFLTNYPS
                     ILDFTNQTVVRTMVGTPYEEEFHSYNHSLPDGKFGIEGVDGMKTGSSPSAAFNAVVTA
                     KRGNTRLITVVLGVGDWSDQNGEFYRHPFINALTEKAFKDSKTLTKAKRSKLKRLAAK
                     PASTAAAAKKQLPQATTDQSFLEKIEQFVDDHRPLVLICLAIFILIVLLLALMAFMMG
                     R"
BASE COUNT          364 a          242 c          264 g          383 t
ORIGIN      
        1 taccaagaag tctttttaat cagcaatgag cttaacgtcc catcataaag gccatcagag
       61 caagtagtaa aacaataagg ataaaaatgg ctaagcaaat caagacaagg ggacgatgat
      121 catcgacaaa ttgttctatt ttttcaagaa atgattgatc agttgtggct tgtggcaact
      181 gctttttggc agctgctgct gtgctggctg gtttagcagc aagcctttta agcttgcttc
      241 gttttgcttt ggtgagtgtt ttactatctt taaaggcttt ttcagtcaaa gcattaatga
      301 atgggtgacg gtaaaattct ccattttggt cagaccaatc accaactcct aggacaactg
      361 taatcagtct ggtatttcct cgttttgctg ttacgaccgc attgaaagca gcacttgggc
      421 tggatcctgt tttcatacca tcaacaccct ctattccaaa cttaccatca ggcagagagt
      481 ggttgtagga atggaactct tcctcataag gggttccaac catggtgcgg acgacagttt
      541 gattggtaaa atcaagaata ctaggataat tggtcaaaaa ataataaatt aaggttgcaa
      601 aatcacgtgc tgttgtgata ttagaagctg ttaaatcata tttttctggg agatagtagc
      661 cttgaaaggc ttgtgcgatt gctccgctag catttgaaaa atgcgtatta gtcatgccga
      721 gctctttggc tgttttgttg atccgatcaa taaaggctga cgcatcgttg ttggataggt
      781 agttggcaat catcactgtt gcagcatttg atgacggaac cactgtcata atgattaaat
      841 cacgaatagg gtacgcaact cctgcaacaa tattattatt gctgatttcg taaattttac
      901 taatcgcctg atcagtctct gttgctgtaa tggtggtatc aagtgttacc tttcctttgg
      961 ccaattcctc aaagaggata taaagcgtaa acatctttga catactagca gggtctctag
     1021 gcatgtcaat gttatcctgc cataagatct ctgaggtctt tgcgtcaaca acaatggagg
     1081 cttttggcct attaacctca ctaacggtat agccagcctt gcgggtaatt tccatgacat
     1141 cttcggcgtg aacctgagaa atgcctagaa agcacaggca caccaaaacg aatagtagca
     1201 atcttttagt caattcaaag ctccttaatg taaaaaaata atgtaagctt att
//
LOCUS       DARYXW010000171         1176 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.172, whole genome shotgun sequence.
ACCESSION   DARYXW010000171 DARYXW010000000
VERSION     DARYXW010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1176
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.172"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            <1..313
                     /locus_tag="TV191_001924"
     CDS             <1..313
                     /locus_tag="TV191_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508387.1"
                     /translation="FENFGFHLNYNNKEIIIWITSTGKNRQFEYGEGGQLMISLPNPK
                     YPDRSFLDRVTLESLLTDTEKIEAVDYAFGRYEHRLEIALAILKDYLDSDEAKVLLKN
                     E"
     gene            306..719
                     /locus_tag="TV191_001925"
     CDS             306..719
                     /locus_tag="TV191_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508388.1"
                     /translation="MSEQYLSIKESLGYKNVKQALWTIFSANLDEISIHEGEDENFNF
                     VFTYKNCEMMMGIYDTGKNIQFQAGEGGLFSVSLPNPKYPEQSFQKIVSLSYLISDKN
                     VSENIRWCLGLDLKSVEYVMRVLKDYLDQKCEEEQ"
     gene            826..>1176
                     /locus_tag="TV191_001926"
     CDS             826..>1176
                     /locus_tag="TV191_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679801.1"
                     /note="This protein contains a domain related to
                     Tuberculosis Necrotizing Toxin, which is the C-terminal
                     effector domain of outer membrane channel protein CpnT,
                     and which has a lethal NAD+-glycohydrolase activity;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycohydrolase toxin TNT-related protein"
                     /protein_id="HEL1508389.1"
                     /translation="MPDGKYAYLSNDIDKATGTPIPVRYRNYLKADGSINWPNYNGFS
                     LDVKGRPIMTPAFLKTGDLLDRYGESGGTFTSPIVDRKVIPFNKRGLPYPEDYQNYHQ
                     YKVLKDINMENVEKG"
BASE COUNT          424 a          164 c          228 g          360 t
ORIGIN      
        1 atttgaaaat tttggttttc atttaaatta taacaataaa gaaatcataa tctggattac
       61 atcaactggt aagaatagac aatttgaata tggagaagga ggacaattga tgatttcact
      121 tcctaatcca aagtatcctg atagatcctt tcttgatagg gtaaccttag aaagtctttt
      181 aacagacacc gaaaaaatag aagcagttga ctatgctttt ggaagatacg agcatcgtct
      241 cgaaatagcg ttggccattc taaaagatta tttagattca gacgaagcaa aggttttatt
      301 gaaaaatgag tgagcaatat ttatcaataa aagaaagctt aggttataag aacgttaaac
      361 aggctttatg gactattttt tcagccaacc ttgatgaaat ttctatacat gaaggagaag
      421 atgagaattt taactttgtc tttacatata aaaattgtga aatgatgatg ggaatttatg
      481 atactggtaa gaatattcaa ttccaagctg gagaaggtgg tttattcagt gtaagtttac
      541 ctaatcctaa atatccggag cagtcatttc aaaaaattgt atcactttct tatttaattt
      601 ctgataaaaa tgtaagtgaa aatataagat ggtgcttagg actggatctg aaatctgttg
      661 aatatgttat gcgtgttttg aaggattatc tggatcaaaa atgtgaagag gaacaataat
      721 tctaatcact tctggagggc atatagatga gtgaagaaca gtatttacca ataccttcga
      781 agagaatacc agttaaaggg aaggtatttt gcagaaagaa tcaccatgcc agatggaaaa
      841 tatgcttatc tgtccaatga cattgataaa gctaccggaa caccaattcc tgtccgatat
      901 agaaattacc ttaaggctga tggttctatt aattggccaa actataatgg ctttagtctt
      961 gatgtaaagg gaaggcctat catgactcca gctttcctaa aaacaggtga tttacttgat
     1021 agatatggag aatctggagg aacattcaca agtccaatcg ttgaccgtaa ggttatacca
     1081 tttaacaagc gaggcttacc atacccagag gactatcaaa attatcatca atataaggtt
     1141 cttaaggata ttaatatgga aaatgttgaa aagggt
//
LOCUS       DARYXW010000172         1161 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.173, whole genome shotgun sequence.
ACCESSION   DARYXW010000172 DARYXW010000000
VERSION     DARYXW010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1161)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1161)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1161
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.173"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(<1..232)
                     /locus_tag="TV191_001927"
     CDS             complement(<1..232)
                     /locus_tag="TV191_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL1508390.1"
                     /translation="MKTLLKLIVFIVGALVLILGMEVKHRMDIYDQVKQVELKNAHSK
                     EAIDIYEKKLKRLDPQALTDEGLIKSYTIDSDS"
     gene            complement(229..630)
                     /locus_tag="TV191_001928"
     CDS             complement(229..630)
                     /locus_tag="TV191_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL1508391.1"
                     /translation="MKTLLKLIVFIVGTLVLMLGMEVKHRMDTYDQIKQVELKNAHSK
                     EVIEMYEQELISMDPQALTDEGLIKSYTIDSDSLFINPMGGFSIHLIINDDPDIYLRV
                     GLGRYDMERNLEIDGIYRSEKLEKLLKGVER"
     gene            complement(705..1097)
                     /locus_tag="TV191_001929"
     CDS             complement(705..1097)
                     /locus_tag="TV191_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL1508392.1"
                     /translation="MNRFLKISLLIVGVIVIMLGMEVKHRMDIYDQIKQEEIKIAQSK
                     EAIVIYEQELKWLDPNALTNEGTIKSYSIDLDSITLNPMGGFSIALHINKNPKYKYRI
                     SLMWNTPMRDLCVGGSSLSPELQELLDR"
BASE COUNT          343 a          237 c          159 g          422 t
ORIGIN      
        1 ttgagtctga gtcaatagta taagacttga taagcccttc atctgttagg gcctgaggat
       61 ccaatctttt taacttcttt tcataaatgt ctatcgcttc tttactatgc gcgtttttga
      121 gttctacctg tttgacttga tcgtatatat ccattctatg ctttacctcc atgccaagaa
      181 taagtacaag ggcaccaaca ataaatacaa taagttttaa caatgttttc atctctccac
      241 tccttttagt agtttttcta acttttctga gcgatagata ccatcaatct ccaaatttct
      301 ttccatatca tatctaccaa ggccaactct caagtaaata tctggatcat cattgataat
      361 taaatgaatg gaaaagcctc ccatcggatt aataaagagt gaatctgagt cgatagtgta
      421 ggacttgata agtccttcat ctgttagggc ctggggatcc attgatatta gctcctgttc
      481 atacatttca atcacttctt tactatgcgc gtttttgagc tctacctgtt tgatttgatc
      541 gtatgtatcc attctatgct ttacctccat gccaagcata agtacaagag taccaacaat
      601 aaatacaatg agttttaaca atgttttcat aactatgctc cttttcatga aaattatatt
      661 gttctttggt gcaatcaatt gtttctgata gcctgtcata atcattacct atctaacaat
      721 tcttgtaatt ctggcgacaa agaggatcct cccacacata aatctctcat tggtgtattc
      781 cacattaaac ttattcgata cttatacttt ggatttttgt ttatatgtaa agcaatggaa
      841 aagcctccca ttggattaag agttattgag tctaaatcaa tagaatagga tttaatagtc
      901 ccttcatttg tcaatgcatt tgggtccaac cattttaact cctgttcata aatcacaatt
      961 gcttctttac tttgggcaat ttttatctcc tcctgcttga tttgatcgta tatatccatt
     1021 ctatgcttta cttccatgcc aagcataatg acaataacac caacaataag cagactgatc
     1081 tttaaaaacc tattcatgtc tatactccta tatcattcct atacttatcg ataaattccc
     1141 aaaaataaat ggaatcattt t
//
LOCUS       DARYXW010000173         1157 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.174, whole genome shotgun sequence.
ACCESSION   DARYXW010000173 DARYXW010000000
VERSION     DARYXW010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1157
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.174"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            <1..377
                     /locus_tag="TV191_001930"
     CDS             <1..377
                     /locus_tag="TV191_001930"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679404.1"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="HEL1508393.1"
                     /translation="HQIFDYNTFSDKLSEALYTGKAIGLAYGPGDLRRSLGHIISVWG
                     ADLDDQNRVVAIYVTDSDDKKLTIGNERVGLKRYKVSSDDQGRARLTTRDKDNTGGEI
                     RSIETLDMGTQEWADYFNKTEK"
     gene            463..>1157
                     /locus_tag="TV191_001931"
     CDS             463..>1157
                     /locus_tag="TV191_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1508394.1"
                     /translation="MLTNQTGYRHRLSKQKLPISMVSCLLGMGVLTSPTLISADDSSP
                     TIIIKSGAGMTIDPQLPKTLLSKPEEKPEETPKLPDERHYGDDVRPEETPKLPDERHY
                     GDDIKPEEMPKLPDERHYGDDIRKPKPEDTPKPPNESGQGNDLKEDLELKKQRRELTE
                     QLRALKTIEEVLEFLRKPIPGFVTDEDWNFLVSFVEKGPENKTFEVDKLKLLEIFSTS
                     QGHRVWLGYLILE"
BASE COUNT          403 a          213 c          248 g          293 t
ORIGIN      
        1 ttcaccaaat ttttgattat aacacttttt cagataaatt aagtgaggct ctctatactg
       61 gtaaagccat tggattggcc tacggacctg gagacttgcg tcgttcacta ggtcatatta
      121 tttctgtctg gggagctgat cttgacgatc agaatcgcgt ggtagctatt tatgtaactg
      181 attctgatga taaaaagtta actataggaa atgagagagt tggtttgaag cgatataaag
      241 tatctagcga tgatcaaggt cgtgctcgtc tgacgactcg tgataaagat aacacaggtg
      301 gtgaaattcg atctattgaa acattagata tgggtacaca agagtgggca gattacttca
      361 acaagacaga aaaataacaa taacccctac acatatatga ttactccaga taaagcacac
      421 agcaatagac tcagccagta aggaaaggac gataacaaaa cgatgctaac aaaccaaacg
      481 gggtacaggc atagacttag taagcagaag ctacctatca gcatggtttc ctgcttgcta
      541 ggaatggggg tgctaacctc tccaacatta atctcagctg atgatagttc tcctactatc
      601 atcattaaat cgggtgcagg tatgacaatt gatcctcaat taccgaaaac tctcctttct
      661 aaacccgaag agaaaccaga ggaaacacct aaacttccag atgagcgaca ttatggtgat
      721 gatgtcagac cggaagaaac accaaagctt ccagacgaga gacattatgg tgacgatata
      781 aaaccggaag agatgccaaa gctcccagat gagcgacatt atggtgatga catcaggaag
      841 ccgaaaccgg aggatactcc aaagccacct aatgaaagcg gtcaaggtaa tgacttaaaa
      901 gaagatttgg agcttaaaaa gcaacgtcga gagcttacag agcagcttcg tgctttaaaa
      961 actattgagg aagttttaga gttcctgaga aaaccaattc ctggatttgt aacagatgaa
     1021 gattggaatt tcttagtatc atttgtagaa aaaggcccag aaaataaaac ttttgaagta
     1081 gataaattaa aattactaga aatcttctca acctcacaag gtcatagagt ttggttaggt
     1141 taccttattc tggaaga
//
LOCUS       DARYXW010000174         1101 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.175, whole genome shotgun sequence.
ACCESSION   DARYXW010000174 DARYXW010000000
VERSION     DARYXW010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1101)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1101)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1101
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.175"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            <1..>1101
                     /locus_tag="TV191_001932"
     CDS             <1..>1101
                     /locus_tag="TV191_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEL1508395.1"
                     /translation="YFSLMFSAGTAIENTEELGFSHLIEHLLLRSGGEQSLNELFDNN
                     GAFIGGETSRDYINLMGYCKAENFKNIFEAIVSRVFNLNLTEEELLREKRVVLVELTQ
                     YENGSKTEKLVSDNRLIFKNSKWSEDIIGVRENIESVDLKKLYKFYTENIQNGEFQIA
                     ISGPNHLKEEIAIIENKLPVGRTPVKSNFPIFSSGVTERKKNQQVSEISMYIDISKMT
                     TSSHDVAILTILNAMLTGVKGSVLGGKLRTKNQWVYNIISFPIFYNGLTILKILTRTP
                     EIHKHQVVQVLKEDLVNREDLKNTKLFDKAKKRVINEVLMSYEVKKVEFLKTLCREKL
                     FNIPSWESVTGEIEKVSLNELNQFAKDALMQNK"
BASE COUNT          422 a          130 c          207 g          342 t
ORIGIN      
        1 tatttttcat tgatgttttc tgcaggtact gccattgaaa atacagaaga acttggtttt
       61 tcacatttga tagagcattt attattacga tcaggcggag aacaatcatt aaatgaacta
      121 tttgataata atggtgcatt tattggaggt gaaacttcta gagattatat taatttgatg
      181 ggttactgta aggctgaaaa tttcaaaaat atatttgaag caatagtaag tagggtattt
      241 aatttaaatc ttactgaaga agaactgcta agagaaaaaa gggtagtttt agttgaacta
      301 acacagtacg agaatgggag caaaacagaa aaattagttt cggataaccg cctaattttt
      361 aaaaatagta agtggtcaga agatattatt ggtgttaggg agaatattga atctgttgat
      421 ttgaaaaagc tttataagtt ttacactgag aatatccaaa acggagaatt tcaaattgct
      481 atttcaggac cgaatcactt aaaagaagaa atagcgatta ttgaaaataa attaccagtt
      541 ggaagaactc ctgttaaatc taattttcct attttttcta gtggtgtaac agaacgaaag
      601 aaaaatcaac aggtttctga aatttcaatg tatattgata tttcaaaaat gacaacatca
      661 tctcatgatg tagcgatatt aacaatttta aatgcgatgt taacaggagt taagggttca
      721 gtgttaggag gtaaattaag gacgaaaaac caatgggtat ataatataat ttcattccca
      781 atcttttaca atgggctcac tatcctaaag atactgacta gaacgcctga aattcataag
      841 catcaagtag tacaagttct aaaagaagac ttagtaaata gagaagactt aaaaaatacg
      901 aaattatttg ataaagctaa aaaaagagtt atcaatgaag ttcttatgag ctatgaagtg
      961 aagaaagtcg agtttttaaa gacactttgc agggagaaat tatttaatat acctagttgg
     1021 gagagtgtta ctggggaaat tgagaaagtt tctctcaatg aacttaatca atttgctaaa
     1081 gatgctctca tgcaaaacaa g
//
LOCUS       DARYXW010000175         1077 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.176, whole genome shotgun sequence.
ACCESSION   DARYXW010000175 DARYXW010000000
VERSION     DARYXW010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1077)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1077)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1077
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.176"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            41..>1077
                     /locus_tag="TV191_001933"
     CDS             41..>1077
                     /locus_tag="TV191_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1634-like element ISSeq4 family transposase"
                     /protein_id="HEL1508396.1"
                     /translation="MAFIKTTTNKEGRTHVYLVEGYRKDGKVKQRILKKFGLLDELEL
                     EEPGILERLKREAKEDTLNNPKVLQVSYDLLAPMNQPDQSYGWMVLDNLFESLGLTAF
                     LKGIKTKSEYDLVQVLKLLVFQRILRPDSKLATYASQADLFGHWDISLNAIYRSLNKL
                     NTLKDDLQHHLHKVVSQMIKREASLVFYDVTNYYFETDIPDNELVSENGEILQEGLRR
                     RGPSKEHRPKPIVQLGLFRDTNGIPISYKLFRGNQTDPVTYLPAVEEVKKQFGIERLI
                     VVADKAMNSMANVSEMLKQEDGWLFSQKHRGRRGAPKDIQEHILDSSDWQFNPELTFA
                     KKSYIRERKLG"
BASE COUNT          337 a          209 c          228 g          303 t
ORIGIN      
        1 tttttcttgt tgtgtatggt tatatatgtt ataataaact atggctttta ttaaaacaac
       61 aacgaataaa gaaggtagga cgcatgtcta ccttgtagaa gggtatcgta aagatggtaa
      121 ggtcaaacag cgtatcctta aaaaatttgg tctcttagat gagcttgaat tggaagaacc
      181 agggattctt gagcgtctta agcgcgaagc taaagaagat actttaaata accctaaggt
      241 actccaggtt tcctatgacc tccttgcccc catgaaccaa ccggatcaat cttatggttg
      301 gatggttttg gataatctct tcgaatctct ggggctcaca gcctttttaa agggtatcaa
      361 aacgaagtct gagtatgact tagtgcaagt gctaaagcta ttagtttttc agagaattct
      421 ccgaccagat agtaaacttg ccacctatgc ctctcaagca gacttatttg gccattggga
      481 catcagctta aatgccattt atcgctcctt gaacaaattg aacaccttga aagatgatct
      541 tcaacatcat cttcacaagg tagtgagtca gatgatcaaa cgtgaagcca gtctcgtttt
      601 ctacgatgtc accaattatt attttgagac agatattcca gataacgagt tggtttcaga
      661 aaatggagag atactacaag aagggcttcg aagacgtggt ccgagtaagg aacaccgtcc
      721 aaaacccatt gtgcaattag gactctttag ggataccaac ggtattccga ttagctataa
      781 actgtttcga ggtaatcaaa ccgatcctgt tacctatctt ccagcggttg aggaagtcaa
      841 aaaacaattt ggaattgagc ggttaattgt agtcgccgat aaggcgatga atagtatggc
      901 taatgtttca gaaatgctca agcaagaaga tggctggctc ttctcacaga aacatcgcgg
      961 acgccgagga gctccaaaag atattcaaga acacatcctt gattcatcgg attggcaatt
     1021 taacccagaa cttaccttcg ctaagaaatc ttatatccgt gaacggaagt tagggaa
//
LOCUS       DARYXW010000176         1043 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.177, whole genome shotgun sequence.
ACCESSION   DARYXW010000176 DARYXW010000000
VERSION     DARYXW010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1043)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1043)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1043
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.177"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            <1..273
                     /locus_tag="TV191_001934"
     CDS             <1..273
                     /locus_tag="TV191_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508397.1"
                     /translation="TIHVLTTSDKVEPDIYKGMLELIAPAKKGQYQEHDVFTVLDDKH
                     EDLAGEGNLVFVYVNEPFEYDKQTLKDLESEDKVTVIKYADLVKQD"
     gene            284..574
                     /locus_tag="TV191_001935"
     CDS             284..574
                     /locus_tag="TV191_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508398.1"
                     /translation="MIDFVQIGAFCGAALSILGVWGFIVNPFKKAMEANELAMAQLKD
                     SIKELAYELKNLDRDREITKKIIDRHEERLGRVEDDIIVNKEQIKTLFKKGD"
     gene            577..756
                     /locus_tag="TV191_001936"
     CDS             577..756
                     /locus_tag="TV191_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508399.1"
                     /translation="MDKWFKKVAIKTIKTMAQTAVGVIGSSALITDVNWQVVTSTVIM
                     SGIVCVLMNVSDIKE"
     gene            868..>1043
                     /locus_tag="TV191_001937"
     CDS             868..>1043
                     /locus_tag="TV191_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL1508400.1"
                     /translation="MTFLDKIKQGCLDGWTKYKILPSLTAAQAILESGWGKYAPYNAL
                     FGIKADSSWTGKSF"
BASE COUNT          331 a          187 c          247 g          278 t
ORIGIN      
        1 actatccacg ttttgacaac cagcgataaa gtcgagcctg acatctacaa aggcatgctt
       61 gagcttattg cgccggccaa aaaagggcaa tatcaagagc atgatgtctt tacggtgcta
      121 gacgacaagc atgaggatct tgcaggcgag ggcaatctcg tctttgtgta tgtcaacgag
      181 ccgtttgagt atgacaaaca aacgctcaaa gacttggagt ctgaggacaa agtcacagtc
      241 attaaatatg cggatttggt aaaacaagat tagaggtggt tagatgatag attttgtaca
      301 aattggtgct ttttgtggcg ctgctttgtc tatcttgggt gtttggggat ttatcgtcaa
      361 tccctttaaa aaagccatgg aagctaacga gctagccatg gcccaactca aagactcgat
      421 caaggagtta gcctacgagc taaaaaatct tgatcgcgat agggagataa ccaaaaagat
      481 tatcgatcgg catgaggagc gtttaggacg tgtagaggac gacattattg tcaataaaga
      541 gcaaatcaaa acattattta aaaaaggaga ctaaaaatgg ataaatggtt taaaaaagta
      601 gcaatcaaaa caattaagac aatggcccaa accgctgtag gggttattgg atcaagcgca
      661 ttgattactg acgtcaactg gcaggtggtg acctcaacag ttattatgtc aggtattgtc
      721 tgcgtcttga tgaatgtgtc tgacatcaag gaatagcatt atgcgagcaa tcacacgatt
      781 agcaatagtc atagcaatca caatactgta tttaccgcta tctgtgattg ctctgattgt
      841 ttatccgttt ttagataagg aggacagatg acctttttag ataagattaa gcaaggctgc
      901 ttagatggct ggaccaagta caaaatcttg ccatctttaa cagcagcaca ggcaatcctt
      961 gagagcggtt ggggtaagta tgccccatat aacgctctat ttggtatcaa ggcagatagc
     1021 tcttggacgg gtaagtcatt taa
//
LOCUS       DARYXW010000177         1030 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.178, whole genome shotgun sequence.
ACCESSION   DARYXW010000177 DARYXW010000000
VERSION     DARYXW010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1030
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.178"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            135..1030
                     /locus_tag="TV191_001938"
                     /pseudo
     CDS             135..1030
                     /locus_tag="TV191_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISSeq3 family transposase"
BASE COUNT          349 a          189 c          220 g          272 t
ORIGIN      
        1 ctaacaattg gggggctatt tttatgacat tgagttatga agacaaggtt caaatctatg
       61 agctacggca cattggaaag tccattaaat gcttatcaga aaagtttagt attgcagaat
      121 ctgacctcaa atacatgatt cgcctgattg acaggtatgg gttagccatt gtccaaaaag
      181 gtaagaatag ttattattct ccagaactga agcaagagat aatagataaa gttctgattg
      241 atggtcaatc tcaaaaacag acgtccttag actatgcttt accaaattct agtatgcttt
      301 caaggtggat agcgcaatac aagaaaaacg gctatactat tcttgagaaa agaagaggga
      361 ggccaccaaa gatgggacgt caaccaaaga agactttaga acaaatgaca gagttggagc
      421 gactccaaaa agaattagac taccttagag cggagaatgc tgtgctaaaa aagctgagag
      481 aataccggtt gagggacgaa gcaaagctca aagagcaaca gaaatcatcc aagaattaat
      541 cggtcaattt tctctagcaa ctttgcttga aatccttgat ttatcgcggt caacctatta
      601 ttatcaagtc aagcaactag ctcaagaaga taaggacatg gacttaaagg agctcattca
      661 aggcatctat gatgaacatc atggcaatta tggctatcgt cgcattcatc tggaactaag
      721 aaatcgtggt tttatcgtca atcacaaaaa agtacaacgt ttgatgactg tcatgggctt
      781 aaaagctcgt atccgtcgta agcgcaagta ttcttcttac aaaggtgagg ttggcaaaaa
      841 ggctgataat ctgattaaac gtcagtttga aggttctaag ccctacgaga agtgctatac
      901 cgatgtgacg gaatttacct tacctgaggg gaaactctat ctatcgcctg ttcttgacgg
      961 ctataacagt gagattattg atttcaccct gtctcgatcg cctgacttga agcaagtaca
     1021 aaccatgctt
//
LOCUS       DARYXW010000178         1016 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.179, whole genome shotgun sequence.
ACCESSION   DARYXW010000178 DARYXW010000000
VERSION     DARYXW010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1016)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1016)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1016
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.179"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(44..754)
                     /locus_tag="TV191_001939"
     CDS             complement(44..754)
                     /locus_tag="TV191_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEL1508401.1"
                     /translation="MAKKKGKLTLISLFVLVACLGVYSSIRQSENTSDVSAETVSTSS
                     TQAFIEEIGATASVVAQERDLYASVMIAQAILESANGKSALSQAPYYNFFGIKGAYNG
                     SSVTMTTWEDDGAGNTYYIDQTFRAYPTVADSLYDYTNLLSSDIYAGARKSNTLSYQD
                     ATAALTGLYATDTSYNWKLNNIIETYGLTAYDIVNNQAQEALAAAPLTSVWNPYRKSY
                     TDTETLAIDKAWAQRMGY"
BASE COUNT          298 a          207 c          176 g          335 t
ORIGIN      
        1 gctagaactc aagccttgga gtgctaagtc atttttctat tctttagtag cccattcgtt
       61 gtgcccatgc cttatcaata gcaagggttt cagtgtctgt atagctcttg cgataaggat
      121 tccagacaga ggtcaaagga gccgcagcaa gcgcttcttg cgcctgatta tttactatat
      181 cataggccgt tagaccgtag gtctcaatga tgttgtttaa tttccagtta tagctagtat
      241 ctgtagcata caagcctgtt aaagctgctg tagcgtcctg ataagacaag gtatttgact
      301 ttctagcacc tgcataaata tctgagctaa gcaaattagt gtaatcatat aaggaatcag
      361 ccactgtcgg ataagctcta aaggtttgat cgatgtagta agtatttcca gccccatcgt
      421 cttcccatgt tgtcatcgtc actgatgacc cattataagc ccctttaatg ccaaaaaaat
      481 tataataagg tgcttgactt aaagctgatt taccgttagc tgactctaaa atagcttgag
      541 caatcataac cgaagcatac aagtctcttt cttgagcaac aacactagca gttgctccaa
      601 tctcttcaat aaaggcttgc gttgacgacg ttgacacagt ctctgctgag acatctgatg
      661 tattttctga ctgtctaatt gaactataaa cacctaagca ggctactaga acaaaaagac
      721 tgataagtgt gagcttacct ttcttttttg ccatttatca ttccctcttt ttttgataaa
      781 tagattatag cacagaatgc tcataaaaag acttatccac aaacaattta atcatattga
      841 taacttttgt ctttaaatcg aaatatttta atgtaaagaa ggcttaccaa gtccataaag
      901 cgaaggcttt tcataatctt ttacgcctta tttgctatat cgccttgtaa tagcttcaat
      961 acctttgaaa ggttattaca cctactattg ttctttatgc ctgtctgtta agtatt
//
LOCUS       DARYXW010000179         1006 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.180, whole genome shotgun sequence.
ACCESSION   DARYXW010000179 DARYXW010000000
VERSION     DARYXW010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1006
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.180"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            <1..>1006
                     /locus_tag="TV191_001940"
     CDS             <1..>1006
                     /locus_tag="TV191_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="HEL1508402.1"
                     /translation="KVVSENENLIEKGLSSIQVMQLSGKLKKTGIKISFAKLMEEPNL
                     SKWYELIDKSRVKSDKNIESSIIQSDESKFDLTDVQYSYLIGREDDQILGGVGCHAYL
                     EIDGENIDEDKLKEAWNKLQYRHPMLRTKFTKDGKQEILYKPYSEEIEVFDLSDLDEE
                     TLHLKLVEIREQKSHRKLNVNQGQVAGVALAKFSDEKSRIFFDVDLLVSDVMSMSIMI
                     KELAELYSGVELDNLNEYTFKDYMQNGIGESINDADKEFWEQKINSFEIERPNLPLRK
                     QPEQIKETKFTRRKRIIKKSEWETIKDIAASYRSTPSMVLLTAYALVLERWCNQDKFF
                     "
BASE COUNT          399 a          119 c          208 g          280 t
ORIGIN      
        1 agaaagtagt ttcagaaaat gaaaatttaa ttgaaaaagg tttaagttcc attcaagtca
       61 tgcaactgtc tggaaaatta aagaaaacgg ggataaaaat ttcgtttgca aaacttatgg
      121 aagaaccgaa tttgtccaag tggtatgaac ttattgataa atccagagtg aaaagtgata
      181 agaatataga gtcatcaatt atccaaagtg atgaaagtaa gtttgattta acagatgtcc
      241 agtactccta tttaatcgga agagaagatg atcagatttt aggtggcgtg ggttgccatg
      301 catatcttga aatagatgga gaaaatattg atgaggataa gttaaaagag gcttggaata
      361 agcttcaata cagacatccc atgcttagaa caaaatttac gaaagacggg aagcaggaaa
      421 tattatacaa accgtacagt gaagaaatag aagtttttga tttatctgat cttgatgaag
      481 aaacgctgca tctaaaatta gtagaaatta gagaacaaaa atctcatagg aaattaaatg
      541 taaatcaagg tcaggttgca ggagtagcac tagcaaaatt ttcagatgag aagtcaagga
      601 tattttttga cgtagatttg cttgtatccg atgtaatgag catgagtatt atgattaaag
      661 aattagctga actttattca ggagtagaac ttgataattt gaatgagtat acgtttaagg
      721 attatatgca aaacggaatt ggcgaatcaa tcaatgatgc agataaggag ttttgggaac
      781 aaaaaataaa ttcctttgaa atagaaagac cgaacttacc attaaggaaa cagccggaac
      841 aaattaaaga aacgaagttt acaagaagaa agagaattat taaaaaaagt gaatgggaaa
      901 ccataaaaga tatagcagca tcgtatcgaa gtacaccatc tatggttctt ctaactgcct
      961 atgctcttgt tcttgaaaga tggtgtaatc aggataaatt ttttat
//
LOCUS       DARYXW010000180         1000 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.181, whole genome shotgun sequence.
ACCESSION   DARYXW010000180 DARYXW010000000
VERSION     DARYXW010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1000
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.181"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(<1..467)
                     /locus_tag="TV191_001941"
     CDS             complement(<1..467)
                     /locus_tag="TV191_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEL1508403.1"
                     /translation="MEYIERPKYLNHIEKFVDKPIIKILTGMRRVGKSTILMMIKDEI
                     LKHVPDEQKIYINFESLEFMSINEASFLASYISEKSKNLSGKLYYFFDEIQLVNNWEK
                     VVNGLRVDQDCDIYITGSNSNLISGELATLLAGRYIEFEIQPFTFGEFLKIFS"
     gene            547..945
                     /locus_tag="TV191_001942"
                     /pseudo
     CDS             547..945
                     /locus_tag="TV191_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820672.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          356 a          172 c          133 g          339 t
ORIGIN      
        1 tcactaaaaa tctttaaaaa ttccccaaaa gtaaatggct gtatttcaaa ttctatatat
       61 cttcctgcaa gaagtgtggc aagttcaccg gaaatcaaat ttgaatttga accggtaatg
      121 tatatatcac aatcttgatc tactcttaac ccattaacta ctttttccca gttatttacc
      181 aactgtattt catcaaagaa ataatataat ttaccactta gattttttga cttttcactt
      241 atataacttg ccaaaaagct cgcttcattt atactcataa actccaaaga ttcaaaattg
      301 atatatatct tttgctcatc cggcacatgt ttcaaaattt catctttaat catcatcaga
      361 atggtagatt ttccaactct tcgcatccca gttaagattt taataatagg tttatcaaca
      421 aatttttcta tatggtttaa atacttgggt cgttcaatat attccatatc attcacctct
      481 ctttagcttt gattatatta tacacgataa aaatatattt tccaatattg ttttcgaata
      541 taatcgaaat atatcataaa agcagccgat gaaaggcaaa atttacagga taagatcaag
      601 gctattgata aggaaatgca ggagctttct gccactatgg agcaagttca cactgttaaa
      661 aaatacaggc aatactacaa agaatataag gcaagtccat ctgacaaggc attttttgaa
      721 gagtacaaag ctcagattac cttatatgaa aatgcccttt cagagcttaa aaaatcatat
      781 tccaagttgc caaattctaa gggtatttta gatagacttg ataaattgca agaaaaaaag
      841 aataccctta tgcaagagta ttcttcctca aaatctatta tggacgaact ttacaagata
      901 cgaaaaaatt atggaattta catgggtaag gagatggaga gataattttt tctctccatc
      961 atcatttatt accaagttga tggtttatgg tttattccat
//
LOCUS       DARYXW010000181          958 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.182, whole genome shotgun sequence.
ACCESSION   DARYXW010000181 DARYXW010000000
VERSION     DARYXW010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 958)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 958)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..958
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.182"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            <1..>958
                     /locus_tag="TV191_001943"
     CDS             <1..>958
                     /locus_tag="TV191_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HEL1508404.1"
                     /translation="QDNQKVRLASNCLGTTRFNQVMIERGDKATDYVAPVVVEGSGES
                     TGVFKSLEEMLSGLQSINLELTDTKNSNLWSKIKLTTNGMLREYHRDHIKTEIVESAD
                     GIAKRIADDTGQKLALINETIKGIKREYQDADRQLSASYQAGIDGLKTQLANDKIGLQ
                     AEIKLSAQGLSQKYDDELRKLYAKITTTSSGTTEAYENKLEGLRAEFTRSNQGMRTEL
                     ESQISGLRSVQQSTAKQISQEIRDRTGAVSRVQQDLASYQRRLQDAEKNYSSLTQTVK
                     GLQSTVSDPSGKIQSRFTQLQNQIDQRVTRDDVMSIINLSGD"
BASE COUNT          308 a          207 c          236 g          207 t
ORIGIN      
        1 gtcaagacaa tcaaaaagtc agattagcca gcaactgtct aggaacaact cgctttaatc
       61 aggttatgat tgagagaggc gacaaagcga ctgactatgt tgcgcctgtt gtcgttgagg
      121 gcagcggtga gtcgacaggt gtgtttaaaa gtcttgagga gatgcttagt ggtctacagt
      181 ctattaattt agagctgaca gataccaaaa actccaatct ttggtcaaaa atcaagctca
      241 cgacaaacgg tatgttacgc gagtatcatc gtgatcatat taaaacagag attgttgaga
      301 gcgcagatgg tattgccaag cggattgccg atgacactgg ccaaaagctg gcactaatca
      361 atgagaccat caaaggtatc aagcgtgagt accaagacgc agatagacag ctatccgcga
      421 gctaccaagc gggcattgat ggcctaaaaa ctcaactggc caatgacaaa atcggtctac
      481 aagctgagat taagctgtca gctcaaggct tgtcgcaaaa gtacgacgat gagctgcgca
      541 agctgtatgc taagattacc accacctcat caggcacgac cgaagcgtac gaaaacaagc
      601 ttgagggctt gcgtgctgag tttacccgta gcaaccaagg catgcgcact gagttagagt
      661 cgcagattag cgggttaagg tctgtgcagc agtcaactgc aaaacaaatc tcgcaggaga
      721 ttagagacag gacaggtgct gttagtcgtg tgcaacagga cttagccagc tatcaaagac
      781 gcttgcagga cgccgaaaaa aattacagca gtttaaccca gacggttaaa ggtctacaat
      841 caactgttag cgatccgtca ggtaaaatcc agtcgaggtt tacacaacta caaaatcaaa
      901 tcgaccaacg tgtgacaaga gatgacgtta tgtcaatcat caacctatcc ggagatag
//
LOCUS       DARYXW010000182          953 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.183, whole genome shotgun sequence.
ACCESSION   DARYXW010000182 DARYXW010000000
VERSION     DARYXW010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 953)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 953)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..953
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.183"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            <1..636
                     /locus_tag="TV191_001944"
     CDS             <1..636
                     /locus_tag="TV191_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="USG protein"
                     /protein_id="HEL1508405.1"
                     /translation="NKYDEITEILSTLVDRFRRKTIFISGSAYSYSAYSQKTGENFIH
                     KLSFELSKNGYHIVNGYGKGVGEFVLNGVADYCLTHKSKINDFLTLMPFPQNSSLGID
                     LDKLYKENREQMIESCGIAIFLFGNKEAEDIASGVMDEYELSKKHGLVCLPIEYTGGA
                     SKEIYDQTTQEISDKNTISAIEQANKQCDGDIDMSVKNIVQAVKILNKEEF"
     gene            637..>953
                     /locus_tag="TV191_001945"
     CDS             637..>953
                     /locus_tag="TV191_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001129326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIR domain-containing protein"
                     /protein_id="HEL1508406.1"
                     /translation="MAKRQVFFSFHYDNDNWRAGQVRNMGKVDSSSTFSDNDWEEVKE
                     KTESKIKEWIDEQLNKRSCLVVLIGEKTANRKWINYEIRKAYELNKGIVGIYIHKLEN
                     SLG"
BASE COUNT          368 a          100 c          197 g          288 t
ORIGIN      
        1 aataaatatg atgaaatcac cgaaatattg agcactcttg tcgatagatt tagaaggaaa
       61 acaatattta tatctggtag tgcgtactcc tattcggctt attctcagaa aactggcgaa
      121 aattttattc ataaactatc ttttgaacta tcaaaaaatg gttatcatat tgtgaatgga
      181 tatggtaaag gagtcggtga atttgtatta aatggagttg cagattattg tttgactcac
      241 aagtccaaaa taaatgattt tttaacactt atgccttttc ctcaaaatag ttcattaggt
      301 attgatttag ataagctata taaagaaaat agagagcaga tgattgaaag ttgtggtata
      361 gctatatttc tttttggtaa taaggaggca gaagatattg caagcggagt tatggacgaa
      421 tatgagttat caaaaaagca tggattagta tgtttgccta ttgaatatac tggcggtgca
      481 tctaaagaaa tatatgatca aacaactcaa gaaatttcag ataaaaatac aataagtgca
      541 attgaacagg caaataaaca atgcgatggc gatattgata tgtctgttaa aaacatagtt
      601 caagcagtta aaatattaaa taaggaggaa ttttaaatgg caaaaagaca ggtatttttt
      661 agctttcatt acgacaatga taattggagg gcaggacagg ttcgcaatat ggggaaagta
      721 gacagtagtt ctaccttttc tgataatgac tgggaggaag taaaagaaaa aactgaaagt
      781 aaaattaaag aatggattga tgaacagtta aataagcgtt catgtttggt tgttttgatt
      841 ggagaaaaaa cagcgaacag aaaatggata aattatgaaa taagaaaagc atatgagtta
      901 aataaaggta ttgtgggaat ttatattcac aagttggaga attcactggg aga
//
LOCUS       DARYXW010000183          945 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.184, whole genome shotgun sequence.
ACCESSION   DARYXW010000183 DARYXW010000000
VERSION     DARYXW010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 945)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 945)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..945
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.184"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            21..934
                     /locus_tag="TV191_001946"
                     /pseudo
     CDS             21..934
                     /locus_tag="TV191_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677204.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
BASE COUNT          335 a          123 c          212 g          275 t
ORIGIN      
        1 agtgtcttga agagggaaac atgttagaca attttggtga aaaggtgaga gaccttcggt
       61 atcagaaaaa aattaccaga gaggatttat gtggagatga gtcagaatta tccattcgtc
      121 aattggcacg aatagaactg ggccaatcga ttcccagcct atcaaaggtg gtttttattg
      181 ctaaggcttt ggacgttagt gtcggctttt tgacagacgg agaggatttg gagctaccga
      241 agcgctatag gagcttaaat atttgatttt aagaacaccg acctatatgg acgatgacaa
      301 attaaagctg cgagaagagc aatttgacga aatttttgaa gattattatg accagttgcc
      361 agaggaagaa aagcttgtgg tggattgctt gcagtccata atggatacgt tattaaccga
      421 gaatatcaat tttggagttg ggttattaca ggaatacttt gaacaaacaa aaagtaagac
      481 tcaatttaga gagaatgatc tcattcttat tgagctgtat ttagcgtacc tcgacattgc
      541 aggaatgaat ggagagtatt cagataaagg attctatgat tctttgttag acattttgtt
      601 aaatcagttt gaacattttg aattagagga attatttatt gtcaataaaa tagctatagg
      661 aatttcctcg ttgagcatca aaaacaataa gccggagatt cttgagaagg ttattgtact
      721 tagtcaaaaa attatcctca agactcagga ttttaataga atgcctatct taaatttgat
      781 agagtggaaa tatgctctaa tgaagaaaaa agacatagaa atggccaaaa aatgctatgc
      841 taaggcatgc ctgtttgctc aattaacagg agatcagtat ttggaaaaga aattgagaga
      901 agaatggggt aaagatataa aacgatatca ataggacaaa aatgt
//
LOCUS       DARYXW010000184          941 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.185, whole genome shotgun sequence.
ACCESSION   DARYXW010000184 DARYXW010000000
VERSION     DARYXW010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 941)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 941)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..941
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.185"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            128..941
                     /locus_tag="TV191_001947"
                     /pseudo
     CDS             128..941
                     /locus_tag="TV191_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          339 a          152 c          209 g          241 t
ORIGIN      
        1 atggggtgct ttttatatga aattaagtta cgatgataaa ttaagaatat atgaactaag
       61 aaaaaatggg atgtcttgtt cccgcattgg tcaacagtat gatattcagg tttctaatct
      121 caaatacatg gtaaagctta tggacagata tggagttgag attgttagaa agggtaaaaa
      181 taagtattat cctccagaat taaaacaaga aataattgat aaagttcttc ttgaaggtca
      241 gtctcaactg tctgtctctc ttgagtatgc tctcccaaat gctggtatgc ttcccaattg
      301 gatagcgcaa tacaagaaaa acgggtatac tattcttgag aaacaaagag ggagaccaac
      361 gaagatgggc cgtaaaccaa agaaaacttg ggaagaaatg acagagctag agcgccttca
      421 ggaagagcta gaatacctta gaacggagaa tgcttatcta aaaaagttga gggagcttcg
      481 tttacaggac gaagccagag aatgagaaag gcagaaacaa ttagagagat ggtccaagaa
      541 ggattccgat taaacctcct acttgagatc gctaagatgg ctcgttcaac ctattattat
      601 caagtcaagc aattggataa gtcagataaa gatgaagcaa tcaactctga aatcaaagcg
      661 atttatgagg agcataaggg aaactatggt taccgtcgca ttcatttaga actcaagaat
      721 cgtgggttta tcgtcaatca caagaaagtg caacgcttga tgaaagagat gagattagct
      781 gctcgaattc gtcgtaaacg caggtattcc tcttacaaag gcgagactgg taagaaggct
      841 gataatctga ttcaacgcca gtttgaagct gctaagccat atgaaaaatg ttataccgat
      901 gtgacagagt ttgctttacc aaacaacgat gaaaaacttt a
//
LOCUS       DARYXW010000185          937 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.186, whole genome shotgun sequence.
ACCESSION   DARYXW010000185 DARYXW010000000
VERSION     DARYXW010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 937)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 937)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..937
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.186"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(<1..89)
                     /locus_tag="TV191_001948"
     CDS             complement(<1..89)
                     /locus_tag="TV191_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEL1508407.1"
                     /translation="MDLTVQNKDLNTLYSVLDKIKVTNMRVNRG"
     gene            complement(98..>937)
                     /locus_tag="TV191_001949"
     CDS             complement(98..>937)
                     /locus_tag="TV191_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HEL1508408.1"
                     /translation="AGGIDAKMSGSEIISAINLNTYGAVIAGKHIALDGNTTVNGTFT
                     TKIAEAIKIKADQIIAGTLDASKARIINLNASSIVGLDANFIRAKIEHTITSLLEGKV
                     IRARNGAMMIDLSNSKIDFNSNATINFNNKDNALVRKDGTHTAFVHFSNATPKNYTGS
                     ALYASIGITSSGDGINSASSGRFCGARFFRYARGYEHTALVDQAEIYGDDIVFSDDFN
                     IDRGFKMRPSLMPKMVDLNKMYQAILALGRCWLHANNTAWTFNSDTTSAIIREYNSYI
                     NGL"
BASE COUNT          248 a          210 c          195 g          284 t
ORIGIN      
        1 ccgcgattaa ctctcatgtt agtaacctta attttgtcta gtacgctata gagcgtattt
       61 aagtctttgt tttgtactgt taaatccatg ttgtctccta taatccatta atatatgagt
      121 tatactctct gatgattgca ctagtagtgt ctgagttaaa ggtccacgct gtattattag
      181 cgtgtagcca gcagcggcca agagctaaaa tggcctgata catcttattg agatcgacca
      241 tttttggcat taggctaggc cgcatcttaa agccacgatc gatgttaaaa tcgtcgctaa
      301 agacaatatc atcaccgtaa atttcggcct gatcgacaag cgctgtgtgc tcgtaacctc
      361 gcgcatacct aaaaaaccta gcaccgcaaa aacgaccgct cgacgcgctg ttaatcccgt
      421 cacctgacga tgttatcccg atcgaggcgt aaagcgcact acctgtataa ttttttggcg
      481 tggcattgct aaaatgcaca aaggctgtgt gggtaccgtc tttacgtacc aaagcgttgt
      541 ctttgttatt aaagttaatg gtagcgttgc tgttaaagtc aatcttagag tttgacaagt
      601 caatcatcat cgctccgttg cgagctctga taactttgcc ctcgagcaaa cttgtgatcg
      661 tatgctcgat tttggccctg ataaaattag catctaagcc gacaatgctg ctagcgttta
      721 gattaatgat acgagccttt gaggcatcta aagtacctgc gataatctga tcagccttga
      781 ttttgatagc ctcggctatc ttagtggtaa aagtgccatt gaccgttgta ttgccatcaa
      841 gagcgatgtg tttacctgca atgactgcgc catacgtatt gagattaatc gctgagataa
      901 tctcgctgcc agacatttta gcatcaatcc caccagc
//
LOCUS       DARYXW010000186          929 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.187, whole genome shotgun sequence.
ACCESSION   DARYXW010000186 DARYXW010000000
VERSION     DARYXW010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 929)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 929)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..929
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.187"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(<1..370)
                     /locus_tag="TV191_001950"
     CDS             complement(<1..370)
                     /locus_tag="TV191_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1508409.1"
                     /translation="MAFFNYSQALTVGQIDIKNARLKAGKTQKELAKLIGVTKQTIIN
                     DEKGTTEPSWDRLQEIATALNVDIDTLFPYNMLGEKRDFKWMEHLERLENNWLYSRMA
                     EEEVLLQKILDFAIFQNKLDK"
     gene            complement(596..668)
                     /locus_tag="TV191_001951"
     tRNA            complement(596..668)
                     /locus_tag="TV191_001951"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(633..635),aa:Lys,seq:ctt)
     gene            complement(670..863)
                     /gene="ssrS"
                     /locus_tag="TV191_001952"
     ncRNA           complement(670..863)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="TV191_001952"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
BASE COUNT          280 a          180 c          153 g          316 t
ORIGIN      
        1 ttttatctaa tttattttga aatattgcaa aatctagaat tttttgaagt aatacttctt
       61 cctcggccat acggctataa agccaattat tttcgagtct ctctaggtgc tccatccact
      121 taaagtctct tttttctcct aacatattgt agggaaataa ggtatcaata tcaacattta
      181 aggctgtagc aatctcttga agcctatccc atgaaggttc agtagtcccc ttttcgtcat
      241 taataattgt ttgcttagta actcctatta atttagcgag ttctttttgt gtttttccag
      301 cttttaagcg agcattttta atatctattt gtccaactgt taaagcctgc gaataattaa
      361 aaaaagccat ttttctccaa attccgtcgc aggtgatgga ggtgaaaata ctccgattgt
      421 atcaccttgt gttaattata ttattgtcat gtgttagctc tctttttaaa aagtaataaa
      481 ttctttattt aacatcatat cataaaaaat tgtttcgggg acaaatggtg ggacaaaccc
      541 tctttaggca agcaaaaaag ccctgcaata aaggcttttt gtcgttttta cactataccc
      601 cctacagggc tcgaacctgt gacccataga ttaagagtct actgctctac caactgagct
      661 aaggaggtaa ggaaagctgt attggcaccg gtgattcacg ttttgtattg aacccgcacg
      721 atataagcag gtgggcaaca tacttctctt cagattgctt ccacgtgaaa cggcttgcat
      781 actagagata gactttgttt ccctaaaata caaaaaaata gtcggtcaac acttagatgt
      841 gaattcgtat gccacagcaa taactctatg ctcttatgat accacttttt gaaaattttt
      901 caagccctaa aatgaaaaaa agatcgtat
//
LOCUS       DARYXW010000187          900 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.188, whole genome shotgun sequence.
ACCESSION   DARYXW010000187 DARYXW010000000
VERSION     DARYXW010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 900)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 900)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..900
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.188"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(<1..367)
                     /locus_tag="TV191_001953"
     CDS             complement(<1..367)
                     /locus_tag="TV191_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508410.1"
                     /translation="MARKLAIIVIATGILFALIACILFFKKDILQVFPRMDIAWVGFL
                     VVAILLCVSGIWVFSISGKKQDWINETDERESLITAKANMVGYVIQTTLLGIVFFLLV
                     FMGYLNKVSGFSIIGVVLIS"
     gene            complement(402..599)
                     /locus_tag="TV191_001954"
     CDS             complement(402..599)
                     /locus_tag="TV191_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004134772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1508411.1"
                     /translation="MKNRLEEIRKENGITQEELASILEVSRQTIGSLENGRYNPSIIL
                     AFKIAKYFSLSIEDIFIYEEE"
BASE COUNT          288 a          177 c          101 g          334 t
ORIGIN      
        1 cacttatcaa aacaactcca attatagaaa acccagaaac tttgtttaaa tagcccataa
       61 aaactagaag aaaaaaaact attcccagta aagttgtttg aatcacatat cctaccatat
      121 tagccttagc tgttattaag gactctcttt catcggtttc atttatccaa tcttgttttt
      181 tacctgaaat tgaaaatacc catattccac taacacacag aagaatagca acaacgagaa
      241 agcctaccca tgcaatatcc attcttggaa atacctgtaa aatatctttt ttaaaaaata
      301 atatgcaagc aatcaaggca aaaagtattc cagtagcaat aactataata gctaactttc
      361 ttgccataac catctctttt tttatatttc ttttcatttt tttattcctc ctcgtatata
      421 aagatatctt caatgcttaa actaaaatac ttagcaattt taaaagctaa aataatggaa
      481 ggattatacc ttccgttttc taaagaacca attgtctgcc ttgatacttc aagaatagat
      541 gctaactctt cctgtgttat tccattttct tttctgattt cctcaagtct atttttcaca
      601 tttaatgacc tcctgcaaca atgacaagct aactttacat atagtataat gttttttaga
      661 gaaaatggca agtatacttt ccataaaatc gtttccttat aggtctagcc cttacttttt
      721 tacatgtacg actcctctat atctgcattt tcctcttata cttctgtctg ttgatgagca
      781 cttgcttctc tttgtgatga tatctttact atgcttttca tttttgggat ttttatctta
      841 attttgagta gtcataacta atgcccgtaa aaacgggctt ttatcttgtt ttaaaactgc
//
LOCUS       DARYXW010000188          860 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.189, whole genome shotgun sequence.
ACCESSION   DARYXW010000188 DARYXW010000000
VERSION     DARYXW010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..860
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.189"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            <1..779
                     /locus_tag="TV191_001955"
     CDS             <1..779
                     /locus_tag="TV191_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_192934711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hyaluronoglucosaminidase"
                     /protein_id="HEL1508412.1"
                     /translation="KLVSSKADKSAVYLKAESKIELDKKLSLTGGVMTGQLKFKPAAT
                     VAYSSSTGGAVNIDLSSSRGAGVVVYSNNDTSDGPLMSLRTGKETFNQSALFVDYKGT
                     TNAVNIAMRQPTTPNFSSALNITSGNENGSAMQIRGVEKALGTLKITHENPNVEASYD
                     ENAAALSIDIVKKANGVGTAAQGIYINSTSGTTGKMLRIRNLNDDKFYVKPDGGFYAK
                     ETSQIDGNLKLKDPIANDHAATKAYVDGEIKKIKALLTAK"
BASE COUNT          291 a          169 c          197 g          203 t
ORIGIN      
        1 ccaaattagt atcaagcaaa gcagataaaa gcgctgttta cttaaaagca gagtcaaaaa
       61 tagagctaga caaaaaattg agtttgacag gtggcgttat gacaggccaa ctaaaattta
      121 agccagccgc cactgttgct tattcctcgt caacgggtgg agcggtcaat attgacttgt
      181 cgtctagcag aggtgctggt gttgttgtct attctaacaa tgataccagt gatgggccgt
      241 taatgagctt gcggacgggt aaagagacct tcaatcaatc ggcgcttttt gtcgattata
      301 agggaacaac aaatgccgtt aatattgcga tgcgtcagcc aaccaccccc aatttttcat
      361 cggcgcttaa tattactagc ggcaatgaaa atggtagtgc gatgcaaatt agaggcgttg
      421 aaaaagcatt gggaacgctc aaaatcacgc acgaaaaccc aaacgttgag gcaagttacg
      481 atgaaaacgc tgcagcgtta tctattgata ttgtcaaaaa ggcaaacggt gtaggaacag
      541 ccgctcaggg aatctacatt aactcaacct caggcacaac tggtaaaatg ctcagaatca
      601 gaaaccttaa tgatgataag ttctacgtca agcctgacgg tggtttttat gccaaggaaa
      661 cttcgcagat tgatggcaac ctgaaactca aggatcccat agcgaatgat catgcggcaa
      721 ccaaagctta tgttgatggt gaaatcaaaa aaataaaagc actcttaacg gctaagtaaa
      781 tgtaaaaagg aggagatatg agcagagacc caacattaac attagacgag tcaaatttaa
      841 cgatcggctc agatggacgt
//
LOCUS       DARYXW010000189          859 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.190, whole genome shotgun sequence.
ACCESSION   DARYXW010000189 DARYXW010000000
VERSION     DARYXW010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..859
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.190"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            60..491
                     /locus_tag="TV191_001956"
     CDS             60..491
                     /locus_tag="TV191_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508413.1"
                     /translation="MIVYLKQHKNYWKLVSIAALIIILGGILTMNWLNGDRDNKGENN
                     YYQVEKDLAMEIVSEFEGVKEISFLSPVQSKETGYWGTTATINKTNEISYSFSMTFSG
                     KLDDYSYYYDKCFKLVKRHKKLTLSQVDLTDIDIKYSKGGK"
     gene            492..782
                     /locus_tag="TV191_001957"
     CDS             492..782
                     /locus_tag="TV191_001957"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508414.1"
                     /translation="MITDKNYNWLAGKVYDVDANKVTIPVRKNTDILNRYVKVLEAED
                     NPDNGMQFTVSKSNRNVLALNYKLRSFYDSKKESHHFIRNGSNFSNGRYIYV"
BASE COUNT          336 a          107 c          163 g          253 t
ORIGIN      
        1 gtttttgtaa aagcaaaaaa cctgcaccac cttatgataa agcataaagg aatataagca
       61 tgatagtcta cctaaagcaa cacaaaaatt actggaaatt agtcagcata gcagctttaa
      121 tcattatttt aggaggaata ctaacaatga attggcttaa tggggatagg gacaataaag
      181 gcgagaataa ctactatcaa gtagagaagg atttagcaat ggaaattgtt agtgagtttg
      241 aaggagtaaa agagattagc tttcttagtc cagtacaatc caaagaaaca gggtattggg
      301 gaacaacagc tactataaat aaaactaatg agatatctta ttctttttcg atgacttttt
      361 caggaaagct tgatgattat tcttactatt acgataaatg ttttaaatta gtgaagcgtc
      421 acaaaaaatt gacattaagt caagtggatc taacagatat tgatattaaa tattctaagg
      481 gagggaaata aatgataact gacaaaaact ataactggct agctggaaaa gtatatgatg
      541 ttgatgctaa taaagtaact attcctgtta gaaaaaatac ggatattctt aatcgttatg
      601 tcaaagtcct tgaagccgaa gacaatcctg acaacggtat gcagtttacg gtgtcaaaga
      661 gtaataggaa tgttctagct ttaaattata aactaaggag cttctatgac agtaaaaaag
      721 aaagtcatca ttttattagg aatggtagca attttagtaa tgggaggtat atttatgttt
      781 agctataatc agaatcaagc gaaaatgtta gaacgacaat ttaaccatga acaaaaacga
      841 attgtcttgt atttgttaa
//
LOCUS       DARYXW010000190          858 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.191, whole genome shotgun sequence.
ACCESSION   DARYXW010000190 DARYXW010000000
VERSION     DARYXW010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 858)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 858)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..858
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.191"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            <1..477
                     /locus_tag="TV191_001958"
     CDS             <1..477
                     /locus_tag="TV191_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009429246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1508415.1"
                     /translation="FNDTIENNIKFGNPNVSKEEIINAAKKSHCHEFIMNLPNGYETI
                     VGEGGDFLSGGEKQRISIARAMLKDAPIIILDEATSSIDPENEYLIQRAISNLSKGKT
                     VIIIAHRIVTIEEADQIIVLKEGEIAQIGKHTELMSQDGLYRDYMRIRGKTEDWKI"
     gene            497..>858
                     /locus_tag="TV191_001959"
     CDS             497..>858
                     /locus_tag="TV191_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase NADP-binding
                     domain-containing protein"
                     /protein_id="HEL1508416.1"
                     /translation="MYNIGVLGCNGNIGSLFMEKVSKWEDNYIYAVSRSHMNFIKKDN
                     IEYIFFDAENIEKLDKFCSKCDVIVNCTGIDKTNIMNICLKNDVNYVDPSFVDTDIMS
                     KKLMETNDNCIICSAGCNP"
BASE COUNT          341 a           81 c          173 g          263 t
ORIGIN      
        1 tttaatgata caatcgaaaa caatataaaa tttggtaatc cgaatgtaag taaggaagaa
       61 ataataaatg cagcgaagaa gtcacattgt catgaattta taatgaattt gccaaatgga
      121 tatgaaacta ttgttggtga aggtggtgat tttttatctg gtggagaaaa acaaagaata
      181 tctatagcaa gggcaatgct aaaagatgct ccaattatta ttttggatga agcaacatca
      241 agcatagatc ctgaaaacga atatttaatt caaagagcaa tatcgaattt gagtaaaggt
      301 aagactgtaa ttattattgc tcatagaatt gtaacaattg aagaagcaga tcagataatt
      361 gttttgaaag aaggagagat tgctcaaata ggaaagcata cagaactgat gagccaagat
      421 ggtctgtata gagattatat gagaatcagg ggtaaaacag aggactggaa aatataatat
      481 agataggagg aggtttatgt ataatatagg agttttaggt tgcaatggta atataggttc
      541 gctttttatg gaaaaagtgt ctaaatggga agataattat atttatgctg tatcgagaag
      601 tcatatgaat tttattaaga aagataacat agaatacata ttttttgatg cagagaacat
      661 agaaaaatta gacaaattct gttctaaatg cgatgtgatt gtaaattgta ctggaataga
      721 taaaactaat attatgaata tatgtttaaa aaatgatgtt aattacgtag atccatcttt
      781 tgttgacaca gatattatgt ctaaaaaact tatggaaaca aatgataact gtataatttg
      841 ttcggcaggt tgcaatcc
//
LOCUS       DARYXW010000191          854 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.192, whole genome shotgun sequence.
ACCESSION   DARYXW010000191 DARYXW010000000
VERSION     DARYXW010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..854
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.192"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            <1..782
                     /locus_tag="TV191_001960"
     CDS             <1..782
                     /locus_tag="TV191_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hyaluronoglucosaminidase"
                     /protein_id="HEL1508417.1"
                     /translation="KLASSKADKSAVYLKAESKIELDKKLSLTGGVMTGQLRLKPNSG
                     IKHSSSVGGAINIDMSKSTGAAMVMYTNKDTTDGPLMILRSDKDTFDQSAQFVDYSGK
                     TNAVNIVMRQPSAPNFSSALNITSANEGGSAMQIRGIEKALGTLKITHENPSLGADYD
                     ENAAALSIDIVKKANGAGTAAQGIYINSTSGTTGKLLRIRNENKDKFYVNPDGGFWSC
                     ANSTVAGNLTVNDPTSEKHAATKKYVDEKIAELKKLIQKTD"
BASE COUNT          312 a          157 c          182 g          203 t
ORIGIN      
        1 ccaaattagc atcaagcaaa gcagataaaa gcgctgttta cttaaaagca gagtcaaaaa
       61 tagagctaga caaaaaattg agtttgacag gtggcgttat gacaggccaa ctacggctta
      121 aacctaatag tggtattaag cactcatctt ccgtaggagg agcgattaac attgatatgt
      181 ctaaatcaac aggtgctgct atggtgatgt atacaaataa agatactact gatggaccat
      241 tgatgatttt acgctctgac aaagatacgt ttgatcagtc agctcaattt gtggattaca
      301 gcggtaagac taatgctgta aatattgtaa tgcgccagcc aagcgcacct aatttttcct
      361 cggcacttaa tataaccagt gccaacgaag gcggtagtgc gatgcaaatt agaggcatcg
      421 aaaaagcatt gggaacgctc aaaattactc atgagaaccc aagtcttgga gcggattatg
      481 atgaaaacgc tgcagcgtta tctattgata ttgtcaaaaa ggcaaacggt gcaggaacag
      541 ccgctcaggg aatctacatt aactcaacct caggcacaac agggaagttg cttagaatta
      601 gaaacgaaaa taaagacaaa ttttatgtaa atccagatgg tggcttttgg tcatgtgcaa
      661 attcgactgt agctggtaat ctaacagtta acgatccaac atctgaaaaa catgctgcga
      721 ctaaaaaata cgtagacgaa aaaattgctg agttaaaaaa acttatacaa aaaacagatt
      781 aaggaggata aatgagtaga gatccaacac taacattaga cgagtcaaaa ctcgtcatag
      841 gaccagacgg ccgc
//
LOCUS       DARYXW010000192          836 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.193, whole genome shotgun sequence.
ACCESSION   DARYXW010000192 DARYXW010000000
VERSION     DARYXW010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 836)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 836)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..836
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.193"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(<1..221)
                     /locus_tag="TV191_001961"
     CDS             complement(<1..221)
                     /locus_tag="TV191_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508418.1"
                     /translation="MIAIEMILTGQEPIRTLKKELDRRLVQSICAPLTLGRLHALQRR
                     YDSEVSRIATDTADHIQTIVNQLDSSIRG"
     gene            complement(241..633)
                     /locus_tag="TV191_001962"
     CDS             complement(241..633)
                     /locus_tag="TV191_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508419.1"
                     /translation="MTALEKIRTAIRQKEEELEEQQEHYHQERLQMAAAHDELRGNYN
                     QLQQLYASSYQAVSSYLRHYDASLITDQYTVLTRLIDDYQHRTEQCYHEQGRKMSQQE
                     EAIDHHYRSQRQAIEKDITALRRQWREG"
     gene            complement(630..>836)
                     /locus_tag="TV191_001963"
     CDS             complement(630..>836)
                     /locus_tag="TV191_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508420.1"
                     /translation="LSWAELEEAYAQAGVTYDSLVGQTKRHFDDKVTQARGLATKFKT
                     VKEQLEEGVERTAAIDQKLGCDFS"
BASE COUNT          165 a          228 c          180 g          263 t
ORIGIN      
        1 tgccctctaa tgctgctatc tagctgattg acaatggtct gaatatgatc tgcggtgtct
       61 gtggcaatcc gagatacctc actgtcatag cgcctttgaa gggcatgaag gcgacctaag
      121 gtcaagggag cacatatgga ctgaactaat ctcctatcca gctctttctt taaagtcctg
      181 atcggctctt gtccggttaa gatcatctct atagcaatca tctttcttat ctccttttcc
      241 ttaaccttca cgccactgac gcctcagcgc tgtgatgtcc ttttctatcg cctgtcgctg
      301 gctgcgatag tgatggtcaa ttgcttcctc ctgctgcgac atcttgcgac cttgctcatg
      361 atagcactgc tctgttcggt gctggtagtc atcaatcagc ctcgttagaa cggtatattg
      421 gtctgttatc agactagcat cataatgtct gaggtagctg ctaacggcct gatagctaga
      481 ggcatagagc tgctgtagct ggttatagtt gcctcttaac tcgtcatggg ctgctgccat
      541 ttggagccgc tcttgatgat agtgctcctg ctgctcctct agctcctctt ccttttgacg
      601 gatagcagtt ctgatctttt ctaatgctgt catgaaaagt cgcatcctag cttttgatca
      661 atagcagctg ttctctcaac cccctcctct agctgctcct ttacggtctt gaactttgtg
      721 gccagtcctc tagcttgagt aaccttgtca tcaaaatgcc tcttggtctg acccacaagg
      781 ctgtcatagg tcactcctgc ctgggcataa gcctcctcta gctccgccca gctcaa
//
LOCUS       DARYXW010000193          829 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.194, whole genome shotgun sequence.
ACCESSION   DARYXW010000193 DARYXW010000000
VERSION     DARYXW010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..829
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.194"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            58..243
                     /locus_tag="TV191_001964"
     CDS             58..243
                     /locus_tag="TV191_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508421.1"
                     /translation="MRPWRNGKTFKTNGKDYRVLKTEDNPDNGMQAIAVAPIKGSEVG
                     KSHIMIVYVKSSYWLAS"
     gene            262..660
                     /locus_tag="TV191_001965"
     CDS             262..660
                     /locus_tag="TV191_001965"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508422.1"
                     /translation="MKKQQSKRRKLIGIVALITILGGILTMNWFNDEKLNRERREQER
                     AAIYFSNTYENIHKIKIIGIDKNLKTGSMNKATIVNSKYYISVTFMGGEIYTGVEQAS
                     KDNEEFLNRRKKAENKTTLSKDIEVIYKEK"
     gene            663..>829
                     /locus_tag="TV191_001966"
     CDS             663..>829
                     /locus_tag="TV191_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508423.1"
                     /translation="MVSDKDYNKLSEKVYDVDANKVTISVRKNTDILNRYVKILKAED
                     TPDNGMQAMAVV"
BASE COUNT          324 a          104 c          178 g          223 t
ORIGIN      
        1 gataaaaatt ataatgatat agccgatggg gtttataagg ttgatgctgg caaagttatt
       61 agaccttggc gaaacggtaa gacttttaaa actaacggga aagattaccg cgtcctcaaa
      121 acagaagaca accccgacaa tggtatgcag gctattgctg tagctccgat taagggtagt
      181 gaggtgggta agagtcatat catgattgtt tatgtaaaaa gcagctattg gctagcgtcc
      241 tagcaataaa aggagttgat gatgaaaaag caacaaagca aacgacggaa actaattggc
      301 atagtggctt taataacaat tttaggagga atactaacaa tgaattggtt taatgacgaa
      361 aaactaaata gagagcgtag agaacaagag agggcagcta tttattttag taatacatat
      421 gaaaatatac ataaaataaa gatcatcggt atagataaaa atttaaaaac aggttctatg
      481 aataaagcta caattgttaa tagtaagtac tatatatccg taacgtttat gggaggtgag
      541 atttatacag gtgtagagca agcttcaaaa gacaatgagg aatttttaaa tcgtcgaaaa
      601 aaagcagaga ataagacaac cttgagtaag gacattgaag ttatttataa ggagaaatag
      661 tagtggttag tgataaagat tataataaac tctctgaaaa agtatatgat gttgatgcta
      721 ataaagtaac tatttctgtt agaaaaaata cggatattct taatcgttat gtcaaaatcc
      781 tcaaagccga agataccccc gacaatggta tgcaagctat ggctgttgt
//
LOCUS       DARYXW010000194          811 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.195, whole genome shotgun sequence.
ACCESSION   DARYXW010000194 DARYXW010000000
VERSION     DARYXW010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..811
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.195"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            <1..668
                     /locus_tag="TV191_001967"
     CDS             <1..668
                     /locus_tag="TV191_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1508424.1"
                     /translation="DKNKDKLLQKKYIKNGKDGKPGLNGQRGPQGEPGKQGPQGPRGD
                     KGETGEKGQDGKPGKQGDRGPAGPQGPRGDKGETGEKGDPGRNGKDGKPGEKGDPGQQ
                     GIPGPKGDPGKDGEKGERGEQGPRGENPTPTPDPMPQPMPDPAPKPESKPEPKPIPQP
                     EVKPQPETKPQQPNKPSTITSQPSGKALPKTNDTGSLITVLGTGLLSLLGLGFLTRRK
                     RKQ"
BASE COUNT          290 a          186 c          184 g          151 t
ORIGIN      
        1 atgacaaaaa caaagataaa ctactacaga aaaaatacat aaaaaatggg aaagacggca
       61 agcctggcct aaatggtcaa cgtgggcctc agggcgaacc tgggaaacaa ggaccacaag
      121 gtcctagagg tgataaaggg gaaaccggag aaaaaggaca agatggtaaa ccgggcaaac
      181 aaggtgatcg tggtccggct ggacctcagg ggcctagagg tgacaaaggg gaaactggag
      241 aaaaaggaga ccctggacgt aatggtaaag acggtaaacc aggtgaaaaa ggggatcctg
      301 ggcaacaagg cattcctggg cctaagggtg atcctggaaa agatggagaa aaaggtgaac
      361 gtggggagca aggacctcgt ggagaaaatc ccactcctac cccagatcca atgccacaac
      421 caatgcctga ccctgcacct aaaccagaat ccaagccaga acctaagccg atacctcaac
      481 cagaggttaa gcctcagcca gagacaaaac ctcaacaacc aaacaagcca tcaaccatta
      541 ctagccaacc tagcggcaaa gcactaccaa aaacaaacga cacaggcagc ttgataacag
      601 tattgggaac aggcttgctc tctcttcttg gactgggctt cttaactaga cgcaaaagaa
      661 aacaataatt aaagcactat ctatagcttt ttaatcattg gctatcaaac aaatcacaaa
      721 aaagcttatc gttttactcc taacgataag ctttttcgta ttctctatta cttggtccca
      781 atactatttt tccagcttta ggctggtttt g
//
LOCUS       DARYXW010000195          796 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.196, whole genome shotgun sequence.
ACCESSION   DARYXW010000195 DARYXW010000000
VERSION     DARYXW010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..796
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.196"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(<1..>796)
                     /gene="galU"
                     /locus_tag="TV191_001968"
     CDS             complement(<1..>796)
                     /gene="galU"
                     /locus_tag="TV191_001968"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEL1508425.1"
                     /translation="LPATKALAKEMLPIVDKPTIQFIVEEALKAGIEEILVVTGKAKR
                     SIEDHFDSNFELEYNLQAKGKTELLKLVDETTAINLHFIRQSHPRGLGDAVLQAKAFV
                     GNEPFVVMLGDDLMDITNPSAKPLTKQLIEDYDCTHASTIAVMRVPHEEVSNYGVIAP
                     QGKAVKGLYSVETFVEKPSPDEAPSDLAIIGRYLLTPEIFAILENQAPGAGNEVQLTD
                     AIDKLNKTQRVFAREFKGERYDVGDKFGFMKTSLDYALKHPQVKDDL"
BASE COUNT          188 a          210 c          198 g          200 t
ORIGIN      
        1 aggtcgtcct tgacctgagg gtgcttgaga gcatagtcaa gtgaggtctt cataaagcca
       61 aacttgtccc caacatcata ccgctctccc ttaaactccc tggcaaaaac ccgctgagtc
      121 ttgttgagct tgtcaatcgc atcggtcagc tgaacctcat tgccagcccc aggcgcctga
      181 ttctccaata tggcaaaaat ctcaggcgtc aacaaataac gtccaataat cgctaagtca
      241 ctaggtgcct catcaggact tggcttctca acaaaggtct ccacactata caagccctta
      301 acagccttcc cttgcggtgc aatcacgcca taattggaaa cctcctcatg cggaaccctc
      361 atcacagcaa tcgttgaggc gtgtgtacag tcataatcct cgataagctg cttggtcaag
      421 ggcttggcac taggattggt aatatccatg aggtcgtctc ctagcatgac cacaaagggc
      481 tcattgccca caaaggcctt ggcttggagg acagcgtccc ctagtcctct agggtggctc
      541 tgacgaatga agtgcaggtt gatggcagtg gtctcatcaa cgagcttgag cagctcggtt
      601 ttgcccttgg cttggagatt gtattcgagc tcgaagttgg agtcaaagtg gtcttcgata
      661 gagcgtttgg ccttgccggt gacgacaaga atctcctcga taccggcctt tagggcttcc
      721 tcgacgatga attgaatggt tggcttatcg acgattggga gcatttcctt ggccagtgcc
      781 ttagtggcag gcagga
//
LOCUS       DARYXW010000196          793 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.197, whole genome shotgun sequence.
ACCESSION   DARYXW010000196 DARYXW010000000
VERSION     DARYXW010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 793)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 793)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..793
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.197"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(219..>793)
                     /locus_tag="TV191_001969"
     CDS             complement(219..>793)
                     /locus_tag="TV191_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEL1508426.1"
                     /translation="KGKDLITIGIYTAIYFVINFAFMLAGMIPVMWIMMPSLIALFTG
                     VPYMMICNKVQKAGAILIMGTVTVLIYYATGQFTTVILATFAVGCILAEIIRAITRYT
                     SFIGNTLSFALFSIGMIGSPLPIWLFKESFFAHISEVGMSQDYINALEKFTSPAILIG
                     VIILTFICSLVGALIAKRMMNKHFKKAGII"
BASE COUNT          303 a          148 c           95 g          247 t
ORIGIN      
        1 tcggtaaaac caaaaattct atcaaataaa gcaaccaata agtaaaaatg aatttgattg
       61 ctatcctaca atatccatta cacattgcat aaacacagtt ccaaattaat agcacaaata
      121 atgcataaac tgtggataca ttaaatatcg taaagtttaa gataaaaagc agggaaatcc
      181 ctgctctcgg atctattttt aatctatatt cacgcatttt atataattcc cgctttttta
      241 aaatgtttat tcatcattct tttcgcaatc aaagccccaa ctaacgaaca aataaaagtc
      301 aaaataataa ctcctatcaa aatcgctggc gaagtaaact tttccaaggc atttatgtaa
      361 tcctgcgaca taccaacctc tgatatatga gcaaaaaatg attctttaaa caaccaaata
      421 ggaagaggcg atcctatcat tccaattgaa aatagtgcaa atgataaagt attccctata
      481 aaacttgtat atctagtaat tgctctaata atttcagcta atatacaacc tactgcaaaa
      541 gttgcaagaa taactgttgt aaattgtcct gttgcataat atatcaaaac tgtaactgtt
      601 cccatgatta aaatagcacc agctttttga actttgttgc aaatcatcat gtatggcacc
      661 cctgtaaata aagctatcag tgaaggcatc ataatccaca taactggtat cattccagct
      721 agcataaatg caaaatttat tacaaaataa attgctgtat aaatgcctat tgttattaaa
      781 tcttttcctt tta
//
LOCUS       DARYXW010000197          791 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.198, whole genome shotgun sequence.
ACCESSION   DARYXW010000197 DARYXW010000000
VERSION     DARYXW010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..791
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.198"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(308..>791)
                     /locus_tag="TV191_001970"
     CDS             complement(308..>791)
                     /locus_tag="TV191_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1508427.1"
                     /translation="LAKLILNYYPKHLYDGEIRIDGRNIAEINSESLYKKIAFVQKND
                     FLVEGNVSDNIKLDGSLNLTDKLKDSLGFDETFLNKKLFRVQSLISEGEKQRIDLARF
                     LNRRYSIYIFDEPTGNLDPARSKAILDYILSIKNAIIIVITHNQDIKTLEQFDEVICL
                     "
BASE COUNT          261 a          145 c           80 g          305 t
ORIGIN      
        1 cacaacaaga aataaaatct gaccaaaaaa ttgagtttcc tttgatttct agaacatcat
       61 tatcatcagc tcctatcctt aatttatcat tttgccatga atatacaatc ctatcctgat
      121 tccattttgg aaaaaaatta ttcattttat tgtcctttct atattttaca aaggcatgca
      181 aattctcatt gcatgccttt gtgattaaac aaaataccaa tttgtggttt gttcatttcg
      241 aacttcgaca aactctagtt ctaaaacttc aaaatcttcc ataatcatgt tcatcacccc
      301 ctttcattta caaacaaatg acttcatcga attgttctaa cgtttttata tcttggttgt
      361 gagtaatcac aatgatgatt gcattcttta ttgataaaat ataatccaat atggctttag
      421 atctagctgg atcaagatta ccagttggtt catcaaaaat ataaatagaa tatctacggt
      481 ttaaaaatct tgctaaatca attctttgtt tttctccttc tgagattaaa gactgaactc
      541 taaataattt tttgtttaaa aatgtttcat caaatcctaa actatctttg agcttgtctg
      601 ttagattcaa actcccatct aatttaatat tgtctgaaac attaccttcc acaagaaaat
      661 catttttttg aacaaacgca atcttcttat acaaactttc tgagttaatt tcagcaatat
      721 ttcttccatc aattcttatt tccccatcat ataaatgctt tggataataa tttaatatca
      781 gttttgctaa t
//
LOCUS       DARYXW010000198          789 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.199, whole genome shotgun sequence.
ACCESSION   DARYXW010000198 DARYXW010000000
VERSION     DARYXW010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 789)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 789)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..789
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.199"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            102..485
                     /locus_tag="TV191_001971"
     CDS             102..485
                     /locus_tag="TV191_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEL1508428.1"
                     /translation="MKKALSLVLLTGLMLASSVPAFAAEETNLPYVEGLGYEVEVFEE
                     DYTQPKLFSYDSGWKSFLGGKWRHGVGSRYVWSKYDHNNKTHKTTVQGAGGQFSYSGW
                     TSAGSRAEASWEKALSGNRAWADVK"
     gene            593..>789
                     /locus_tag="TV191_001972"
     CDS             593..>789
                     /locus_tag="TV191_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508429.1"
                     /translation="MKKTVGILAILLIIVIGIGKFFYSDGMFLNIFIKEFNTTVNIVT
                     KPEIADKTIIELQKIANKNDL"
BASE COUNT          285 a           86 c          175 g          243 t
ORIGIN      
        1 ctcataggta taggaacgga gattgagtag agttttggga aactttattc ggaagaaaaa
       61 ttttacaaaa aatttaagta tttgagagag gagaatttat catgaaaaaa gcattgtcat
      121 tagtattatt aacaggtttg atgttagcat catctgtacc agcatttgca gcagaagaaa
      181 caaacttgcc atatgttgaa ggtcttggtt atgaggtgga agtatttgaa gaagattata
      241 ctcagccaaa gttgttcagt tatgatagcg gatggaaaag ttttttaggt ggaaaatgga
      301 gacatggtgt aggtagtcga tatgtttggt ctaaatacga tcacaataat aaaacacata
      361 aaactacagt acaaggtgct ggtggtcaat tctcttattc gggttggaca agcgctggaa
      421 gtagagcaga agcttcttgg gaaaaagctt taagtggtaa tagggcttgg gctgatgtta
      481 aataacaata aataaaaaat agttgaacga gtttgagcgg tgccacgttg ttattttagc
      541 attgtggcat tactcatact cgctattttt ataaagttgg agatgataca gaatgaaaaa
      601 aacagtgggt atattggcaa ttttactaat tatagtgatt ggtataggaa agtttttcta
      661 ttcagacggc atgtttttaa atatattcat aaaagagttt aatactactg taaacattgt
      721 aacaaagcca gaaatagctg ataaaacaat aattgaattg cagaaaatag ctaataaaaa
      781 tgatttaag
//
LOCUS       DARYXW010000199          772 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.200, whole genome shotgun sequence.
ACCESSION   DARYXW010000199 DARYXW010000000
VERSION     DARYXW010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..772
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.200"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(<1..>772)
                     /locus_tag="TV191_001973"
     CDS             complement(<1..>772)
                     /locus_tag="TV191_001973"
                     /inference="COORDINATES: protein motif:HMM:NF012873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508430.1"
                     /translation="IDELPLTEIQSAYLLGRRNHFELGGVASHVYMEVILPLLDIDRA
                     EKVWNDIILKHDALHSIFTSNNTQKVLKEFAYYKIECNEGADIKEKIALTRDKLKGKS
                     YNADIWPLFDISVSQLDDNSLLHLSFDFLILDWASIWILLKEFEECYFDGKTIMDNSY
                     DLKEIRTSQLKLKHSSKYLSDKDFWERRIPFLPDAPLLPIKNKIVKNGFERIQLRIDE
                     NTWSKIKSNISEIGVTQTSFLVTILALVLNRWSSNSEFT"
BASE COUNT          254 a          142 c           89 g          287 t
ORIGIN      
        1 ggtaaattca gaattagaac tccatctatt aagaacaaga gctaatattg tcaccaagaa
       61 agatgtttgc gtgacaccaa tctcacttat attagatttt atcttcgacc aagtattttc
      121 atctattcta agttgtattc tttcaaaacc atttttgact attttatttt taattggtaa
      181 tagtggagcg tcaggcaaaa aaggaattct tctttcccag aaatctttat ccgataaata
      241 cttagaacta tgtttcagtt taagttgact cgttcttatt tctttaagat cataagaatt
      301 atccataatc gtctttccgt caaaataaca ctcttcaaat tcctttaata aaatccaaat
      361 gcttgcccaa tctaaaatca aaaaatcaaa tgataaatgc aataaactat tgtcatctaa
      421 ctgacttaca cttatatcga atagtggcca tatatctgca ttataacttt tccccttaag
      481 tttatccctt gttaatgcaa ttttttcttt tatatctgca ccctcattgc attcgatttt
      541 atagtaagca aattccttca gtactttctg agtattgttt gatgtaaata ttgaatgtaa
      601 tgcatcgtgc tttagtatta tatcattcca aaccttttca gctcgatcta tatccaatag
      661 aggtaatatt acttccatat aaacatgact ggcaacacca ccaagttcaa aatgatttct
      721 tctacctaat aaatatgcac tttgaatttc tgttaaaggt aattcatcaa ta
//
LOCUS       DARYXW010000200          750 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.201, whole genome shotgun sequence.
ACCESSION   DARYXW010000200 DARYXW010000000
VERSION     DARYXW010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..750
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.201"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            89..>750
                     /locus_tag="TV191_001974"
     CDS             89..>750
                     /locus_tag="TV191_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bro-N domain-containing protein"
                     /protein_id="HEL1508431.1"
                     /translation="MDEIKLYENKEIRSIWDEEKEEWYFSVVDVVGVLTEQENVRGAS
                     TYWAVLKKRLKEEGNELLTICKQLKMKATDGKMRLTDVADMQGIFRIIQSIPSPKAEP
                     FKLWLAEVGKERIDEIIDPELTIDRALETYLKKGYTREWINQRLQAIQVRKELTDAWD
                     DHGIQKGKEYAILTDEITKAWSGMTTRGYKNLKGLKKENLRDNMTTLEIVLNMLAEAT
                     TT"
BASE COUNT          304 a          101 c          165 g          180 t
ORIGIN      
        1 aaattataaa tttaaggtat aatataaggt attaaaaagg gaaaagacct gtttaacagg
       61 ataagatata aaagaggcag gtgtcagaat ggacgaaata aaattgtatg aaaataaaga
      121 gatacgctcc atttgggacg aagaaaaaga agagtggtat ttttcagtag tcgatgtagt
      181 tggagttttg acagaacaag aaaacgtaag aggtgctagt acctattggg ctgtactaaa
      241 aaagagatta aaagaagaag gaaatgaact gcttacaatt tgtaagcagt tgaaaatgaa
      301 agcaacagat ggaaaaatgc gtttaactga tgtagcagat atgcaaggaa tattccgtat
      361 tatccagtcc atcccatccc ctaaagcaga accttttaag ttatggcttg ctgaggttgg
      421 aaaagaacga attgatgaaa ttatcgatcc tgaacttacg attgacagag ccttagaaac
      481 ttatctaaag aagggatata cacgtgagtg gataaatcaa agacttcaag ccattcaggt
      541 aagaaaagaa ctgactgatg cttgggatga ccatgggata caaaaaggca aagaatacgc
      601 aattcttact gatgaaatca ccaaagcatg gtccggaatg acaacaagag gttataaaaa
      661 tctgaagggt ttgaaaaagg aaaatctaag ggataatatg accactcttg aaatagttct
      721 taatatgctt gcagaagcca caacaacaaa
//
LOCUS       DARYXW010000201          750 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.202, whole genome shotgun sequence.
ACCESSION   DARYXW010000201 DARYXW010000000
VERSION     DARYXW010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..750
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.202"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
BASE COUNT          220 a          113 c          137 g          280 t
ORIGIN      
        1 tattgtttaa agaagtttga aaccacatta gtgcctgcaa ataaatctaa aaaaaacttc
       61 ttcatcacca gttttatgtt tgtctagcat ggtcttaatt tctgtcaaca ataatttttt
      121 agaaccaata tatctcattc tacatcctta atcatccttt agttgtttca ttatagcata
      181 ttcatgttga agttccaata ttttatttga aaaattatct tttgctgtat ttctttattg
      241 tagtttttaa gcttagttta tatgttgttg attaaaggga agaagaactt aggttatcta
      301 aattgaggaa ttcgtctgta ggtaacaatg tattatgtgg ccgagagatt tattttatat
      361 attaatgaga tataagaccc ctatcccgtc cagcgtgaca gacttgctat ggaaaagctt
      421 attttgaggc tgtctgaggc ttgcttatgt gtgacaagca tttaggctag aacgctcacc
      481 ttttttactg caagcaaagc tttagaagct attgcaagat acttttaggc ttgttactaa
      541 gcgggtcatc tctatcatct cctagagagt agtggaggct atgacagttt agcatatatg
      601 gtttctctaa tgatttgacg atgtaaaacc ataactactg ttattgtagg gattatgtat
      661 aatatgtata aaaagagaag ggcttgtttc tcagcgttat cattttacct ataatgtcgc
      721 tgccagtttg caaggctgct gagattagta
//
LOCUS       DARYXW010000202          748 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.203, whole genome shotgun sequence.
ACCESSION   DARYXW010000202 DARYXW010000000
VERSION     DARYXW010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 748)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 748)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..748
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.203"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            11..>748
                     /locus_tag="TV191_001975"
     CDS             11..>748
                     /locus_tag="TV191_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HEL1508432.1"
                     /translation="MFIIKGEVSRKDLIREIEKAIKSDELGAFIGAGLSIPAGFCSWK
                     ELLREPAEEIGLDVEKESDLVNLAQYYSNSKKRTSIDDLIKGQFSQLVKPTENHKLLS
                     QLPISTFWTTNYDKLIEKALENNMKKPYVKTKDEQLRGTNHNFDAIVYKLHGDVETPE
                     DAVITRSDYEEFGYNKRKLFREVLEGDLLTKTFLFLGFSFEDPNFNYVIGRLRVLLDE
                     KNTRKHYCIMKRVQDADEDYEYKKARQE"
BASE COUNT          301 a           76 c          152 g          219 t
ORIGIN      
        1 aagggaggag gtgtttatta ttaaaggtga agtatccaga aaagatttga ttagagaaat
       61 tgaaaaagct attaaaagtg atgaattagg agcatttatt ggagcaggat tatcaattcc
      121 tgccggattt tgtagttgga aagaacttct aagagaacct gcagaagaaa ttggattaga
      181 tgttgaaaaa gaaagtgatt tggttaactt ggctcagtat tattctaatt caaaaaagag
      241 aacatcaata gatgacttga tcaaaggtca attttctcaa ttagtaaagc ctactgaaaa
      301 tcataaatta ttgtcgcagc tgcccatttc aactttttgg acaacaaatt atgataagtt
      361 aatagaaaaa gctttagaaa ataatatgaa aaagccttat gtaaaaacaa aggatgaaca
      421 attaagaggt acaaatcata attttgatgc gatagtatat aagctgcatg gtgatgtaga
      481 aactcccgaa gatgcagtaa taacaagaag tgattatgaa gagtttggat ataacaaaag
      541 aaaattattt agagaggttt tagaaggaga tttgcttact aaaacatttc tatttttggg
      601 atttagtttt gaagatccaa attttaacta tgtaattgga aggttaaggg tcttactcga
      661 tgaaaaaaat acaagaaaac attattgtat tatgaaaaga gtccaagatg ctgatgagga
      721 ttatgaatac aaaaaagcaa gacaggag
//
LOCUS       DARYXW010000203          747 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.204, whole genome shotgun sequence.
ACCESSION   DARYXW010000203 DARYXW010000000
VERSION     DARYXW010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..747
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.204"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            1..747
                     /locus_tag="TV191_001976"
                     /pseudo
     CDS             1..747
                     /locus_tag="TV191_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000371017.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
BASE COUNT          270 a           87 c          147 g          243 t
ORIGIN      
        1 aaatcgaaat ttattggaaa tattggataa tccaataaat caattacagg attataaatc
       61 aattgagtcg ttagaaacat attatgctag tgaaggaatt ggtgggatta aactattaaa
      121 aatgttaggg aatctaaaga tttctattct gggatgtggt ggtggtggat ctcatattgc
      181 attacaatta gctcaattag gagtgggaag aattcatttg gtggattacg atattgttga
      241 agaaaacaat atcaacagac aatccatgtt cacatttaac gatgtcggaa attacaaagt
      301 tgattgtgta gccaaaaata ttcagcaaag aaattctaaa tgtttggtta ccaaaagcac
      361 ttctaaaatg attaatgtac ctgatgtaaa aaaaagaaat atctgaaagc gattgggtat
      421 tctgttgcat ggatgaacct ccttatatag cacagaggat tgtaaataga gcatgttatt
      481 tattaaaaat tccaagtata tactgtttta gccaacgtag tgcggggaaa cttttgtttt
      541 gtaatcctaa tattgaagat tctggctgta ttgattgttt gttatctgaa caagataatg
      601 aaaactttca aaagctggtg acaacgttca ctacctataa taggaaattg gtaactgcaa
      661 atatcttacc aaatatttta ttattgacat cgtgggtggt taaacgatgg ttagattgtg
      721 taacagataa aaatagtaat gtatgga
//
LOCUS       DARYXW010000204          729 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.205, whole genome shotgun sequence.
ACCESSION   DARYXW010000204 DARYXW010000000
VERSION     DARYXW010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 729)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 729)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..729
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.205"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(<1..702)
                     /locus_tag="TV191_001977"
     CDS             complement(<1..702)
                     /locus_tag="TV191_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HEL1508433.1"
                     /translation="MGMWFEYVNKEMENTKASLFVFPFAGGGVSSFRRWGNQFKDINL
                     FVAQYPGRENRFSEKAISNIEELVKGLFEDLKMTFDFNSPYYFFGHSMGTKIAYELAL
                     KIKENGLPNPNGIIISAGRAPCYKEPNPIYHLDDEGFIEGLRRYDGTPNEILDNKDLI
                     GIFLPTLRADFIIDEDYQDTKGEKLNSKILGLMGDIDEEMELEELLKWQDYTTKEFSY
                     RYINGKHMFVNTSPES"
BASE COUNT          222 a          158 c           87 g          262 t
ORIGIN      
        1 actttcagga gatgtattta caaacatatg cttgccatta atatatctgt aagagaattc
       61 tttcgtcgta taatcttgcc attttaaaag ttcttcaagt tccatttctt catcaatatc
      121 acccatcaga cctaaaatct tgctattcaa tttttcccct tttgtatcct ggtagtcctc
      181 atcgataata aaatcggctc ttagtgttgg taaaaaaatc ccaatcaaat ctttattgtc
      241 taatatctca tttggagtac catcatatct tcttaaccct tcaataaatc cttcatcatc
      301 taaatgataa atcggattcg gttccttata gcaaggggct cgcccagctg atatgataat
      361 tccattcgga tttggtaacc cattttcttt aattttcaga gccaattcat aagcaatctt
      421 agttcccata ctatgcccga aaaaataata aggtgagtta aaatcaaaag tcatttttaa
      481 gtcttcaaac aatcctttta caagttcttc tatgttgcta attgcttttt cagaaaacct
      541 gttttctctc cctggatact gtgcaacgaa gagatttata tctttaaatt gattacccca
      601 tcttctgaat gatgatactc caccacctgc aaatggaaac acaaataaac tagctttcgt
      661 gttttccatt tctttattaa cgtattcgaa ccacattccc atcaaaacac cttccatctg
      721 attattaat
//
LOCUS       DARYXW010000205          720 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.206, whole genome shotgun sequence.
ACCESSION   DARYXW010000205 DARYXW010000000
VERSION     DARYXW010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..720
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.206"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(92..562)
                     /locus_tag="TV191_001978"
     CDS             complement(92..562)
                     /locus_tag="TV191_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEL1508434.1"
                     /translation="MLEVIKNWVNICVKEGDKILLLNRQHDDFPGWIQPGGKVNTSES
                     FFEAAVRELKEETGLTALNLQLKGISGFTNPDKPERYVYYDFLCEDFEGKLLTKSREG
                     LPQWHAIADLDKLDMQEDIRQRLPLYWRQGSFERLHYWSDKEKKVVKTITHLYD"
BASE COUNT          211 a          135 c          144 g          230 t
ORIGIN      
        1 tcaaggcttt tgcaggagat ttatgaaaaa gaaaaattta ggatagtgta agtataagct
       61 agtttcctta agaaaagctt aactgaagca attaatcgta gagatgggtg attgttttga
      121 cgactttttt ctccttgtca gaccaataat gaaggcgttc aaaagatcct tgtcgccagt
      181 agagtggtag cctttgtcga atatcctctt gcatgtctag cttatctaga tcagcaatag
      241 catgccattg tggtaggccc tctcgtgatt tagttagcag cttgccttca aaatcttcgc
      301 aaagaaagtc ataataaaca tagcgctcag gcttatcagg attggtaaag cctgagattc
      361 cctttaattg cagatttaag gcggttaagc cggtctcctc ctttagctca cgcactgccg
      421 cttcaaaaaa ggattctgag gtgttaacct tgccacccgg ttggatccag ccaggaaaat
      481 cgtcatgctg gcggttgaga agtaggatct tgtcgccctc cttgacacag atattaaccc
      541 aatttttgat gacttcaagc attagttacc tcgtttttag ttttatttta tcaaaaaaag
      601 atcagtatga atagctgaga gatttattga tatggtcata atggcttcag atagttttac
      661 tgctgcttta gccatctgca taaataatat aaaaatacca tttcacatca ttatttaata
//
LOCUS       DARYXW010000206          695 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.207, whole genome shotgun sequence.
ACCESSION   DARYXW010000206 DARYXW010000000
VERSION     DARYXW010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..695
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.207"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(1..674)
                     /locus_tag="TV191_001979"
                     /pseudo
     CDS             complement(1..674)
                     /locus_tag="TV191_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622164.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
BASE COUNT          228 a          148 c          100 g          219 t
ORIGIN      
        1 atagataatc aactcctcca gctttttaat aaaaaaatca acataaaaag ctgccttgtc
       61 atgataatat ttaagagagt gatgtgagct gcctttctat gttgtggaag agaaaggaaa
      121 atcttatctc gttcgataaa tgcttttccc aaaaaaatca tatcctcatc agataaaata
      181 gccaaacaac cgccaaaaat gtatagctca tactccgtcc actcttcaat actataaagg
      241 tattctgtca acaattgctt gtctgattct tcaattttaa catttggatc aagtgagtag
      301 atagcacttt taatgattaa ttcatttaat ctattataaa cagaaaaaat gtcatcaccc
      361 ttatattggc tcagaagctc cttcaatcca tctatatctg atgctgtttg tagctcggca
      421 accttggtgc ctaactgaaa aaaatcgctg actttatacc catttacagc atgaccaaat
      481 tcagcgaatg tcatatggat tcctgaaata gctaatagta gtttgtcagc tgccagcatg
      541 ctctggccat tttcaaactt agatagctgt gaaactgata aattgtctct agcaacgtcc
      601 tttagcctaa gtccacgagc aatacgaagc tccttataaa gctctcccag tctcatcaaa
      661 tctgtactat tcattatact ctctctacac atagt
//
LOCUS       DARYXW010000207          672 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.208, whole genome shotgun sequence.
ACCESSION   DARYXW010000207 DARYXW010000000
VERSION     DARYXW010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..672
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.208"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(<1..>672)
                     /locus_tag="TV191_001980"
     CDS             complement(<1..>672)
                     /locus_tag="TV191_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEL1508435.1"
                     /translation="AGKGTRMKSGLPKVLHKVSGLSMLEHVLNSVSALAPQKQLTVIG
                     HQAEQVRAVLGDQSLTVVQEEQLGTGHAVMMAEEELSGLEGQTLVIAGDTPLIRGESL
                     KALLDYHIREKNVATILTANAKDPFGYGRIIRNVAGEVVNIVEQKDANEAEQEVKEIN
                     TGTYIFDNKRLFEALKHLTTDNAQGEYYLTDVISIFKAGQERVGAYLLKDFDESLGVN
                     DRLALA"
BASE COUNT          140 a          183 c          152 g          197 t
ORIGIN      
        1 gctagggcta ggcgatcatt aacccctagg ctctcatcaa aatccttcag caggtaagcg
       61 ccaacccttt cttggccagc cttgaaaata ctgatcacat cggttaggta gtactcccct
      121 tgggcattat cagtcgtgag atgctttaga gcctcaaaga ggcgcttatt gtcaaagata
      181 taagtccctg tgttgatctc cttgacctct tgctctgcct cattagcgtc cttttgctca
      241 acgatattga ccacctctcc tgctacattg cgaatgattc gtccatagcc aaagggatcc
      301 ttggcattgg ctgtgagaat ggttgccaca ttcttttctc tgatatgata gtctagcaga
      361 gccttgagac tttctcctct gatcaagggg gtgtcacctg caatcactag ggtttgtccc
      421 tctaagccag atagctcctc ttctgccatc atgactgcat ggcctgttcc tagctgctcc
      481 tcttgcacca ctgtcagtga ttgatcacct aggacggcac gtacctgctc tgcctgatga
      541 ccgatcactg tgagttgctt ttgaggagct agggctgaga cgctattgag gacatgctcc
      601 agcatgctta agcctgatac cttgtgcagc accttgggaa gccctgattt catgcgggtt
      661 ccctttccag ct
//
LOCUS       DARYXW010000208          619 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.209, whole genome shotgun sequence.
ACCESSION   DARYXW010000208 DARYXW010000000
VERSION     DARYXW010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 619)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 619)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..619
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.209"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(68..583)
                     /gene="lepB"
                     /locus_tag="TV191_001981"
     CDS             complement(68..583)
                     /gene="lepB"
                     /locus_tag="TV191_001981"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEL1508436.1"
                     /translation="MLIVGAVLLRIFVFSTYRVTSEASNAYLNKGDLITIKKNIEPKY
                     KDFVVYTVDKKDYVSRVVAVAGDRVTYMDDIFYLNNMVESQSYLESMKAKYLNHAPIG
                     TLYTEDFTISTVTSGKYDSIPKGKYLLLNDNRKNHHDSRQFGLIDVSQIKGLVTFRVL
                     PLKDFGFVEVE"
BASE COUNT          212 a          128 c           94 g          185 t
ORIGIN      
        1 aaaaatcttg tcaacaagaa aattggtata gtcatatttt gagaaacaaa atagagcagc
       61 cttaaagcta ctctacctct acaaatccaa agtctttcaa aggaagcact ctaaatgtta
      121 ctaatccctt aatttgtgac acgtcaatta agccaaactg acggctatca tgatggtttt
      181 ttctgttatc atttagcaaa aggtatttcc ccttgggaat gctatcgtat tttccagaag
      241 taaccgtcga aatcgtaaaa tcctccgtat aaagcgtacc aataggggca tgattgagat
      301 actttgcctt catactctca aggtaggatt gggattcaac catattgttc aggtaaaaaa
      361 tatcgtccat ataggtaaca cgatcacctg ctactgctac aacccggctc acataatcct
      421 ttttgtcaac cgtataaacc acaaaatcct tatatttagg ctcaatattt ttcttaatgg
      481 tgattaaatc gcccttattc aaataggcat ttgaagcctc tgacgtgact cgataggtcg
      541 aaaaaacaaa tattctaaga aggacagctc ccacaataag aatcaataac aacaatatat
      601 ttcttataaa atctcgctt
//
LOCUS       DARYXW010000209          618 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.210, whole genome shotgun sequence.
ACCESSION   DARYXW010000209 DARYXW010000000
VERSION     DARYXW010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 618)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 618)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..618
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.210"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            185..>618
                     /locus_tag="TV191_001982"
     CDS             185..>618
                     /locus_tag="TV191_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL1508437.1"
                     /translation="MRYTLNKNKRARNYGLCSAAIALAAVASLGTAGSAKAEEAKTLD
                     QLPNPEEQILYNYWDTNDQKAREYLGDLYGFLKSYLGELEKKAKEPGPAGPKGEKGEK
                     GEKGETGPMGPQGLKGEDGKDGAPGEKGEKGDPGIQGPKGEKG"
BASE COUNT          244 a          110 c          149 g          115 t
ORIGIN      
        1 caatgtcaat aacatcaatc aaaaatcaga cgattaggat tttgattaaa aaaaaaaaaa
       61 acgaaaccaa agattgaaat tgatagatag ctattcccac tctaatagtg gacatgttag
      121 aatttccttt gggaaaggaa gttacaggaa actaagactg tttctaccac aaaaggagag
      181 aaagatgaga tacacattaa acaaaaacaa gcgtgctcgt aactacgggc tatgctcagc
      241 agctatcgct ctagcagcag tagccagcct aggaacagct ggcagcgcta aagctgagga
      301 agcaaaaaca ttagaccaac tacctaatcc agaagagcaa attctatata attattggga
      361 cacaaatgat cagaaagcaa gagaatatct tggagaccta tacggtttcc taaaatctta
      421 tttaggagag ttggaaaaaa aagctaaaga gcctggacct gctggaccta aaggtgaaaa
      481 aggcgaaaaa ggcgaaaaag gcgagaccgg tccgatgggg cctcaaggcc taaagggtga
      541 ggacggaaaa gacggcgcac ctggagaaaa aggagaaaaa ggtgatccgg gtatccaagg
      601 ccctaagggg gaaaaggg
//
LOCUS       DARYXW010000210          607 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.211, whole genome shotgun sequence.
ACCESSION   DARYXW010000210 DARYXW010000000
VERSION     DARYXW010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..607
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.211"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            51..281
                     /locus_tag="TV191_001983"
     CDS             51..281
                     /locus_tag="TV191_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002846351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508438.1"
                     /translation="MKNIDEKILMTDGEIKQLQNKRKKPIIQSKQEERKKRDRRLYEK
                     GAVNQKILKIIEKREQTEENIEVQEEATDTEE"
BASE COUNT          278 a           85 c          127 g          117 t
ORIGIN      
        1 tggtttactg tttttttgtt gctcaaaaca gaaagagagg aaaatagaaa atgaaaaaca
       61 tagatgaaaa aattttaatg acagatggag aaatcaagca gttacaaaac aaaagaaaaa
      121 agcccatcat tcagtcgaaa caggaagaga gaaaaaagag agatagacgc ctttatgaaa
      181 agggagcagt caatcaaaaa atcctaaaaa tcatagagaa aagagaacaa acagaagaaa
      241 acatagaagt gcaagaggaa gcaacggaca cagaggaata gtcccttgtt tacaagagtg
      301 tacatataca cctcaacagg tgcgtgcgtt ctccgaaggc tcttgcagag ggcatatcag
      361 ctaacgttga tacagcagag attattttat ttgagagtgc caagaaatat ctaaaagagc
      421 atttgggcga aagcaagacc ttagtcatta gcaaatgaaa atcggaagtc gccaatatga
      481 agaaagaaaa aaagagctta cacaataaaa tattagagat acgagaaaaa attaaacagg
      541 cagaaaaagt taagacttgt atagagcagt tataaaaaca agaaaagcga ttaacacaga
      601 caaagaa
//
LOCUS       DARYXW010000211          582 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.212, whole genome shotgun sequence.
ACCESSION   DARYXW010000211 DARYXW010000000
VERSION     DARYXW010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 582)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 582)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..582
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.212"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            <1..>582
                     /locus_tag="TV191_001984"
     CDS             <1..>582
                     /locus_tag="TV191_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1508439.1"
                     /translation="KNWINTILDFASDCKGKLILSVVMASIGVFFSIIPYWSVYKLMA
                     VFIEQKATGEDVLYYGAIGIIAYFIRYICHGVSTILSHISAYTILRNIRENLGEKLLS
                     ISMGNASKKTIGEYKSIIVDKVETIEMPLAHIIPECVAALLLSLGIAIFMVFISWEMA
                     LAMFITVPFALMAYKKLMGNFNQLYEAQMKSNK"
BASE COUNT          201 a           73 c          109 g          199 t
ORIGIN      
        1 acaaaaactg gataaatact atattagatt ttgcttcaga ttgtaaagga aagttgattt
       61 tatcagtagt tatggctagt ataggagtgt tctttagcat tataccttat tggtcagtat
      121 ataaacttat ggcagtcttt atagaacaaa aagcaactgg agaagatgta ttgtattatg
      181 gagcgattgg tattattgca tattttatca gatatatttg ccatggagta tcaacaatat
      241 tatctcatat atccgcttac acaatcttaa gaaatataag agaaaattta ggtgaaaaat
      301 tgctcagtat ttctatggga aatgcgtcaa aaaagacaat aggagaatat aagtcaatta
      361 ttgtagacaa agttgaaaca attgagatgc ctctagcaca tatcatacca gagtgtgttg
      421 ctgcattgct tttatcacta ggtattgcaa tatttatggt cttcataagt tgggagatgg
      481 ctcttgcgat gtttattaca gtgccttttg ctttgatggc atataaaaaa ctaatgggta
      541 attttaatca gctttatgaa gctcaaatga aatctaacaa gt
//
LOCUS       DARYXW010000212          575 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.213, whole genome shotgun sequence.
ACCESSION   DARYXW010000212 DARYXW010000000
VERSION     DARYXW010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..575
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.213"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(<1..>575)
                     /locus_tag="TV191_001985"
     CDS             complement(<1..>575)
                     /locus_tag="TV191_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HEL1508440.1"
                     /translation="AGGIDAKMSAKEIISAINLNGYGVRISGERIALDGNTTVNGAFG
                     AKLGEFIKLKADQIIGGTIDAAKIRVINLNASSIVGLDANFIRAKIEHTITSLLEGKV
                     IRARNGAMMIDLNSAKMDFNSNATINFNNKDNALVRKDGTHTAFVHFSNATPKNYTGS
                     ALYASIGITSSGDGINSASSGRFCGARFFRYA"
BASE COUNT          159 a          148 c          110 g          158 t
ORIGIN      
        1 gcatacctaa aaaacctagc accgcaaaaa cgaccgctcg acgcgctgtt aatcccgtca
       61 cctgacgagg ttatcccgat cgaggcgtaa agcgcactac ctgtataatt ttttggcgtg
      121 gcattgctaa aatgcacaaa ggctgtgtgg gtaccgtctt tacgtacaag cgcattgtcc
      181 ttgttgttaa agttaatggt agcattgcta ttaaaatcca ttttagccga gtttaaatca
      241 atcatcatcg ctccgttgcg agctctgata actttaccct caagcaaact tgtaatcgta
      301 tgttcaattt tagccctgat aaagttagca tctaagccga caatgctgct agcgttaaga
      361 ttgatcactc taatcttagc agcgtcaatc gtaccaccaa tgatttgatc agctttgagc
      421 ttaataaact caccgagctt agccccaaat gccccattga cggtcgtatt accgtccaga
      481 gcaatacgct cgccagagat ccgcacgcca tagccattaa gatttatcgc tgagataatc
      541 tctttagcgc tcatcttagc gtcaatacca ccggc
//
LOCUS       DARYXW010000213          569 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.214, whole genome shotgun sequence.
ACCESSION   DARYXW010000213 DARYXW010000000
VERSION     DARYXW010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..569
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.214"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            65..>569
                     /locus_tag="TV191_001986"
     CDS             65..>569
                     /locus_tag="TV191_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003033294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEL1508441.1"
                     /translation="MNDTHLILPIKNFINDSYCRDISNKVKSSQKIKREKGDFISAFA
                     PYGYKKSDENKNKLVVDEQAAPNIKNIFDMKLLGYSSKAIADELNHLGVLTPRKYKES
                     QGFKCNGFQNIKGGNWSAKSVNRIIENEVYIGNTLQGKSVTLNYKNKKQIEREKEDWI
                     RVENTHDA"
BASE COUNT          239 a           70 c          110 g          150 t
ORIGIN      
        1 atttccggaa aacgggataa gatttatatc tgtaaatgac aactatgata gtaaaagtgc
       61 ggatatgaat gatacacatc taatactccc tataaaaaac tttatcaacg acagctattg
      121 ccgagatatt tccaataaag taaagagttc tcagaagata aaaagagaaa aaggggattt
      181 tatcagtgct tttgcacctt atggatataa aaaatctgat gagaataaaa ataagttggt
      241 ggttgatgaa caagctgctc ctaacatcaa aaatatattt gatatgaagc tcttgggata
      301 ttcctcaaag gcaatcgcag atgaattaaa tcacttaggt gttttgactc cgaggaaata
      361 taaagaaagt caaggcttta agtgtaatgg atttcaaaat ataaaaggtg gtaattggtc
      421 agcaaagtca gtaaacagaa ttatagaaaa tgaagtatat attgggaaca ccttgcaagg
      481 caaaagtgtt accttaaact ataaaaataa aaaacagata gaaagagaga aagaagattg
      541 gataagagta gaaaatactc atgatgcaa
//
LOCUS       DARYXW010000214          568 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.215, whole genome shotgun sequence.
ACCESSION   DARYXW010000214 DARYXW010000000
VERSION     DARYXW010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..568
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.215"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            16..>568
                     /locus_tag="TV191_001987"
     CDS             16..>568
                     /locus_tag="TV191_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508442.1"
                     /translation="MISVKKNLCRLGVLSSSLLLLTAATTPSVIAFADIQTSAIKNNT
                     DDADGMYFVQSYEMSVEDKELLVRNVKANHPTVSEDFIREVIERQLVGDYTLPEEETL
                     FRSAWQGVTVDQLGAALDVAIGMALTGGAGSIAAGVLRVGKREAVGRVKSILIKYGLG
                     KMIAEIPVDYMLNLLSPGYHIARY"
BASE COUNT          184 a           76 c          126 g          182 t
ORIGIN      
        1 gcatggtgaa tcaatatgat ttctgtaaag aaaaatttat gtcgcttagg tgttttgtct
       61 agtagtttat tacttttaac agctgcaacg actccatctg tcattgcttt tgcggatatt
      121 caaacaagtg ccataaaaaa taatacagat gacgcagatg gtatgtattt tgttcaaagt
      181 tatgaaatgt ctgtagaaga taaagaattg cttgttcgaa atgttaaagc aaatcatcct
      241 acagtttctg aagattttat cagagaagtt attgaaagac aattagtagg tgattataca
      301 ttacctgaag aagagactct tttccgctca gcatggcaag gggttacagt agatcaattg
      361 ggagcagctc tagatgtggc tattggtatg gcattaacag gtggagctgg atcaattgct
      421 gctggtgttt tgagagtcgg aaaaagagaa gctgttggtc gggtaaaatc aattctaatt
      481 aaatatgggc taggtaaaat gatagctgaa attccagtcg attacatgtt aaatttatta
      541 tcgccaggat atcatatagc tagatata
//
LOCUS       DARYXW010000215          562 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.216, whole genome shotgun sequence.
ACCESSION   DARYXW010000215 DARYXW010000000
VERSION     DARYXW010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 562)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 562)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..562
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.216"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            248..>562
                     /locus_tag="TV191_001988"
     CDS             248..>562
                     /locus_tag="TV191_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1508443.1"
                     /translation="MKLEKGDIVKTALSENTTVLDVKDNQAVLFSGTQFVLATGIKEN
                     KESGKFEWDNGRYANDLKSISDIQNNNFETMKETLSFLAEYNHSDFVKGILSLETGIE
                     NED"
BASE COUNT          243 a           55 c          111 g          153 t
ORIGIN      
        1 tgaattcact aaaatgaaaa ataaggtata cgaatttaat caaaaaaaat atccgggtta
       61 tgaggatatg gatataaaac taacaatatc tactattaag ggtatcgagg atttcgatac
      121 ccttaatgat ttttatgata gtttgaaaag gaagggatat ttagaagcga taaaagaaag
      181 tattaaaaat attattgata aagaattaga agaaaacata caagtaaaag tacaggaggt
      241 aaaaaatatg aaattagaaa aaggcgatat tgtaaaaaca gcattaagtg aaaacacaac
      301 agttttggat gtgaaagata atcaggcggt actgttttca ggtactcagt ttgtacttgc
      361 aacagggatt aaagaaaaca aggaaagcgg aaaatttgaa tgggataatg ggcgatatgc
      421 aaatgattta aaaagcattt ccgatataca aaacaataat tttgaaacga tgaaagagac
      481 cttatctttt ttagcagagt ataatcatag cgattttgtc aaaggaattc tgtctcttga
      541 aacaggaata gaaaatgagg at
//
LOCUS       DARYXW010000216          556 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.217, whole genome shotgun sequence.
ACCESSION   DARYXW010000216 DARYXW010000000
VERSION     DARYXW010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 556)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 556)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..556
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.217"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            <1..381
                     /locus_tag="TV191_001989"
     CDS             <1..381
                     /locus_tag="TV191_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508444.1"
                     /translation="GGFRRGETYTISFSQTCELLKKVAITLTQANNKGVKLVLTPTKA
                     KMEAQTFNLSKDKEVISVYPLSYRAALTGDWYKSKQVDLNAAEVQNLALEMAYRDVVD
                     SNNASLVLDWSENPDVIFDGNGGS"
     gene            381..>556
                     /locus_tag="TV191_001990"
     CDS             381..>556
                     /locus_tag="TV191_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL1508445.1"
                     /translation="MSETISAIVVHKSMTKNEWESSDIILPQGQLVYESDTGHSKFGD
                     GKNRYADLIYQGGPP"
BASE COUNT          175 a           95 c          140 g          146 t
ORIGIN      
        1 ggtggtttta gacgcggcga gacatacacg attagcttta gccagacctg tgagttgctc
       61 aaaaaagtgg ctatcacgct gacgcaagct aataataagg gagttaaact ggtactgaca
      121 cctaccaaag ctaagatgga ggcgcagacc tttaatctaa gtaaagataa ggaggtcatc
      181 agcgtctatc ctttgagcta cagagccgct ttaactggtg actggtataa atctaagcaa
      241 gttgacttaa atgcggcaga ggtccaaaat ttggctctgg agatggctta tagagacgta
      301 gttgatagca ataatgctag tttagttttg gattggtcag aaaatccaga tgttattttt
      361 gatggaaatg gaggtagtta atgtcagaga ctatatcagc tatagttgtg cataaaagca
      421 tgacaaaaaa cgagtgggag tctagtgaca tcattttgcc acaaggccag ctcgtctatg
      481 agtctgacac aggccatagt aaatttggcg acggtaaaaa tagatatgca gatttgatct
      541 atcaaggtgg gccacc
//
LOCUS       DARYXW010000217          546 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.218, whole genome shotgun sequence.
ACCESSION   DARYXW010000217 DARYXW010000000
VERSION     DARYXW010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 546)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 546)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..546
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.218"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            <1..287
                     /locus_tag="TV191_001991"
     CDS             <1..287
                     /locus_tag="TV191_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEL1508446.1"
                     /translation="YNENKLNRVLYGASNSLCNRLVKKIVGRPVRNHSLRHTYASFLI
                     LKGVDLISISQLLGHENLNITLKVYAHQLDKLKEKNNQAIKDIFGNLTDF"
     gene            complement(394..464)
                     /locus_tag="TV191_001992"
     tRNA            complement(394..464)
                     /locus_tag="TV191_001992"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(430..432),aa:Cys,seq:gca)
BASE COUNT          169 a          103 c           93 g          181 t
ORIGIN      
        1 attataatga aaataagcta aatagggtgc tctacggagc ttctaattca ctctgcaata
       61 gattggttaa aaaaattgtt ggtcgtcctg tacgcaatca ctctctacgt catacttacg
      121 catctttttt aatcttaaag ggtgttgacc taatatccat atctcagttg cttgggcatg
      181 agaatttgaa cattacgctt aaggtatatg cccatcagct agataagcta aaagaaaaga
      241 acaatcaggc cataaaagat atttttggaa atttgaccga cttttgaccg actttatttc
      301 tttttttctc tttttttatc ctgccacaaa aaataaaaac cttgatttaa caacgttttt
      361 acgaggttaa tcaaggattc gtttgtatat aaaaggcggt agacggattt gaaccgacga
      421 tcaagctttt gcagagccgt gccttaccac ttggctatac cgccataaca agaactattt
      481 taccctagtt gatagcattc gtcaagataa aaatagcagc tattttttag caggctgctc
      541 cttttt
//
LOCUS       DARYXW010000218          540 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.219, whole genome shotgun sequence.
ACCESSION   DARYXW010000218 DARYXW010000000
VERSION     DARYXW010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 540)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 540)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..540
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.219"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(316..>540)
                     /locus_tag="TV191_001993"
     CDS             complement(316..>540)
                     /locus_tag="TV191_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1508447.1"
                     /translation="IQGQGEHGHKGHHGKDAKPSAPKADSKSTAKAMAPAAQKGTLPA
                     TGETNHPFFTLAALGVIASAGMLTLKGKKN"
BASE COUNT          136 a           95 c          124 g          185 t
ORIGIN      
        1 tctagaaata gtatcataac tatcttgtta aagaggttga agaaattagc gcatagaaaa
       61 aacgtatcag ttacgattat agtctagttt gtctttatga aatatagata acactgtaca
      121 atccttttct tttattgtac gactttatac aaagaaaagc ccttggaaat tattttctaa
      181 ggactttttt caatttgaga ggctggtgat agcctctttt tgaacttagg tcatcttctt
      241 agggcaatgc tgcctgaaga gatgagaaaa gctgttacta gctcattgcc taaggggaaa
      301 ggtgcaatgg ctggtttagt ttttcttgcc ttttaatgtt agcatgccgg cgctagcgat
      361 aacaccaagg gctgcaaggg tgaagaatgg gtgatttgtc tcccctgtag ctggtagtgt
      421 gcccttttga gctgctggcg ccatagcttt tgctgttgat ttagaatctg ctttaggtgc
      481 tgatggctta gcatcttttc catggtgacc cttatgtcca tgctcgcctt ggccttggat
//
LOCUS       DARYXW010000219          519 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.221, whole genome shotgun sequence.
ACCESSION   DARYXW010000219 DARYXW010000000
VERSION     DARYXW010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..519
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.221"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            <1..262
                     /locus_tag="TV191_001994"
     CDS             <1..262
                     /locus_tag="TV191_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEL1508448.1"
                     /translation="YNFRVNTEMMEEAKRILEAKNISVPDALNLFVERVVEEKDLPIK
                     TAEQIRAESFLNELISELDEGYQDILAGRTKPANEVFSKYGL"
     gene            252..>519
                     /locus_tag="TV191_001995"
     CDS             252..>519
                     /locus_tag="TV191_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEL1508449.1"
                     /translation="MAYDIYISNKAEQDLDEIYNYYLTEFSHSSAQKVIESLQSAISI
                     LEISPEGYVDFDDRVGRKLFPEGQLRMIPSKHFIVFYLIRQSRVD"
BASE COUNT          180 a           70 c          102 g          167 t
ORIGIN      
        1 gtataatttt agagtaaata cggaaatgat ggaagaagca aagcgtattt tagaagctaa
       61 aaatattagt gttccagatg ctcttaatct atttgttgaa cgggtggtgg aagaaaaaga
      121 tttacctatt aaaactgcag aacaaattag agctgaatca tttttaaatg aactgatatc
      181 agagcttgat gaagggtatc aagatatttt agcaggacgt acgaagccag ctaatgaggt
      241 attttcaaaa tatggcttat gatatctata tttcaaataa ggcagaacaa gatttagatg
      301 aaatctataa ctactattta acagaatttt cgcactcaag cgctcaaaaa gttattgaat
      361 ctttgcagtc agctatttct attcttgaga tatcccctga aggttatgtt gattttgacg
      421 atcgtgtagg acgtaaacta tttcctgaag gccagctaag gatgattcct agtaagcatt
      481 tcatagtatt ttatttaatt cgtcagtcaa gggtagata
//
LOCUS       DARYXW010000220          514 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.222, whole genome shotgun sequence.
ACCESSION   DARYXW010000220 DARYXW010000000
VERSION     DARYXW010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..514
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.222"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            <1..>514
                     /locus_tag="TV191_001996"
     CDS             <1..>514
                     /locus_tag="TV191_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1508450.1"
                     /translation="LESEIQDKNSVLSDEENVKEDNNTTSEKSNENKEKANTVNINGN
                     IASDIDIKNLTSKDGRDFTVASFAVAENDKEGNVKYTNCLAYNDKVSSVENLKKGDFV
                     HVFGKEKISQGKDGKEYTSLKVYSAKLLKAKEQSKTNQNAKDVKKPSALGKLKEYKEK
                     AGEKSKEQVSV"
BASE COUNT          224 a           58 c          114 g          118 t
ORIGIN      
        1 tttagaaagc gaaatacagg ataagaatag tgttttatcc gatgaggaaa atgtaaagga
       61 ggacaataat actacgagtg agaagtcaaa tgaaaataag gaaaaagcaa atactgtaaa
      121 tatcaatggc aatattgctt cagatataga cattaaaaat ttgacatcga aagatggtag
      181 agattttact gttgcaagtt ttgcagttgc tgaaaatgac aaggagggaa atgtaaaata
      241 taccaactgt ttagcctata acgataaggt aagtagtgta gaaaatttga aaaaaggaga
      301 ttttgttcat gtattcggaa aagaaaaaat cagtcaggga aaggacggaa aggaatatac
      361 atctcttaaa gtttattctg caaagctgtt aaaagccaaa gaacagagca aaacaaatca
      421 aaatgcaaag gatgtaaaga aaccgtcagc acttggcaag ttaaaagagt ataaggaaaa
      481 ggcaggcgaa aaatcaaagg aacaggtcag tgtc
//
LOCUS       DARYXW010000221          511 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.223, whole genome shotgun sequence.
ACCESSION   DARYXW010000221 DARYXW010000000
VERSION     DARYXW010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..511
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.223"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            <1..398
                     /locus_tag="TV191_001997"
     CDS             <1..398
                     /locus_tag="TV191_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508451.1"
                     /translation="LIGGLLMVFSLNGKITEEQQKKDLETSIAKLLVHDYEGVKTIKF
                     QGWGHSRETGSWGTTVIINESNQMSFSFSSIKTLEDIGSTRYNPNTFKLVEKPETDSK
                     PRIMDRMNEINATSLAGVTVIYSNNNQED"
BASE COUNT          185 a           67 c          107 g          152 t
ORIGIN      
        1 ttctcatagg agggttgctt atggtattta gtttgaatgg taaaatcaca gaagaacaac
       61 aaaaaaagga tttggaaacc agcattgcta agctgcttgt tcatgactat gaaggggtta
      121 aaaccattaa atttcaagga tggggacatt ctcgtgaaac gggttcgtgg ggaacgacgg
      181 tgattattaa tgagagtaat caaatgagtt tttctttttc tagtataaaa actttagaag
      241 atataggaag cacaagatat aatcccaata cttttaaatt ggtagaaaaa cctgaaactg
      301 attctaaacc aagaattatg gataggatga acgagattaa tgcgacctct cttgcaggtg
      361 ttactgttat ctattcaaat aacaatcagg aggattaata tggcgatatc cgatagtagc
      421 tataatgagt tagcaagaca gacctataat atcgaactaa ggaaagctaa atttaatgat
      481 gtccctattg ttttaatgga aagattatta g
//
LOCUS       DARYXW010000222          495 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.225, whole genome shotgun sequence.
ACCESSION   DARYXW010000222 DARYXW010000000
VERSION     DARYXW010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..495
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.225"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(180..473)
                     /locus_tag="TV191_001998"
     CDS             complement(180..473)
                     /locus_tag="TV191_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
                     /protein_id="HEL1508452.1"
                     /translation="MQKELLPLGSVVYLEGATSKLMIVGRGPIFESNGQNVYSDYVGV
                     MYPEGINPEDAIFFNHEDIAKTVFEGFKDEEEQRFLEVYSDWESTLEISKIKL"
BASE COUNT          149 a          100 c           64 g          182 t
ORIGIN      
        1 tttttttacc gattctattg aaatgctacc tttatttaat gagcataaat gctattataa
       61 cactcatttt aaagcctttt ctaaactttg gaactttaga ggtatttaag ccagagaaag
      121 tcataatctt tcaatataat catgacaatc tactgacaaa tatatctgct acagttcatc
      181 tatagcttta ttttggaaat ttctaaagta ctctcccaat cagaatacac ttctaaaaag
      241 cgttgttctt cttcgtcctt gaagccttca aagactgttt ttgcaatatc ttcatggttg
      301 aaaaaaatcg cgtcttctgg attgatccct tctggataca ttactccaac ataatcactg
      361 tagacatttt ggccattaga ttcaaatata ggaccacgtc cgacaatcat tagcttgctt
      421 gttgctccct ctagatagac aacacttcct aacggtaata attctttttg catatgatta
      481 ctccttatat cgttt
//
LOCUS       DARYXW010000223          451 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.226, whole genome shotgun sequence.
ACCESSION   DARYXW010000223 DARYXW010000000
VERSION     DARYXW010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..451
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.226"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(6..79)
                     /locus_tag="TV191_001999"
     tRNA            complement(6..79)
                     /locus_tag="TV191_001999"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(43..45),aa:Ile,seq:cat)
     gene            complement(100..173)
                     /locus_tag="TV191_002000"
     tRNA            complement(100..173)
                     /locus_tag="TV191_002000"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(137..139),aa:Met,seq:cat)
     gene            complement(184..257)
                     /locus_tag="TV191_002001"
     tRNA            complement(184..257)
                     /locus_tag="TV191_002001"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(221..223),aa:Pro,seq:tgg)
     gene            complement(264..337)
                     /locus_tag="TV191_002002"
     tRNA            complement(264..337)
                     /locus_tag="TV191_002002"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(301..303),aa:Arg,seq:acg)
     gene            complement(352..436)
                     /locus_tag="TV191_002003"
     tRNA            complement(352..436)
                     /locus_tag="TV191_002003"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(400..402),aa:Leu,seq:taa)
BASE COUNT          121 a          135 c          103 g           92 t
ORIGIN      
        1 cattatggac cttgtaggac tcgaacctac gaccgctcgg ttatgagccg agtgctctaa
       61 ccagttgagc taaaggtcca aaacaatcca aaaacaaaat agcggcgaag gggatcgaac
      121 ccccgacctc ccgggtatga accggacgct ctagccagct gagctacacc gccatcaaac
      181 taatcgggaa gacaggattc gaacctgcga caccttggtc ccaaaccaag tactctacca
      241 agctgagcta cttcccgtaa ctatgcaccc tagaggagtc gaacctctaa ccgcctgatt
      301 cgtagtcagg tactctatcc agttgagcta agggtgcttt tccttatgct atgccgagga
      361 ccggaatcga accggtacga tgttaaccat cgcaggattt taagtcctgt gcgtctgcca
      421 gttccgccac cccggctccc caaaagcgaa c
//
LOCUS       DARYXW010000224          437 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.227, whole genome shotgun sequence.
ACCESSION   DARYXW010000224 DARYXW010000000
VERSION     DARYXW010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.227"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            <1..>437
                     /locus_tag="TV191_002004"
     CDS             <1..>437
                     /locus_tag="TV191_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1508453.1"
                     /translation="KIVFKNLNLSIRSGEILGIIGNNGVGKTTLLRCIAGLHKETKGE
                     ITLNGDVISGKKRQRLSAMVMQDVNYQLFADSLVEECCLGNNCDNIQIDKVLGELKLI
                     ESKKSHPMILSGGQKQRLVVANAILSDKKILIFDEPTSGLDYEG"
BASE COUNT          176 a           43 c           88 g          130 t
ORIGIN      
        1 aaaatagttt ttaaaaattt aaatctaagc ataagatctg gagaaatatt aggaattata
       61 ggaaataacg gtgttggaaa gactacactt cttcgatgta ttgcaggatt acataaagaa
      121 acaaaaggag aaattacatt aaatggtgat gttataagtg gcaaaaaaag acaaaggcta
      181 tctgcaatgg ttatgcaaga tgtgaattat cagttatttg cagatagctt agtagaagaa
      241 tgttgcttag gaaataactg tgataatata caaattgata aggttttggg tgaactaaaa
      301 ttaattgagt caaaaaaatc acatcctatg atactttccg gtggacaaaa acaaaggtta
      361 gtagttgcaa atgcgatttt atctgataag aaaatattaa tttttgatga accgacatca
      421 ggattggatt atgaagg
//
LOCUS       DARYXW010000225          421 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.229, whole genome shotgun sequence.
ACCESSION   DARYXW010000225 DARYXW010000000
VERSION     DARYXW010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.229"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            <1..418
                     /locus_tag="TV191_002005"
     CDS             <1..418
                     /locus_tag="TV191_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEL1508454.1"
                     /translation="LKKVQRFDTVGKKKLKVDEKYYLTDHGFRQARGYSNTKDIERTL
                     ENIVYIELVSRGYRVEIGKVKDLEIDFIASKDNERLYYQVSYLMETEETRKREFGVYD
                     FVRDNYPKFVLSMDKVDFSQNGIIHKNVIDFLLESK"
BASE COUNT          167 a           35 c           88 g          131 t
ORIGIN      
        1 actaaaaaaa gtacaaagat ttgatactgt aggaaaaaag aagttaaagg ttgatgaaaa
       61 atattatctt acagatcatg gatttaggca ggcaagagga tactccaata caaaggatat
      121 tgaaagaaca ttggaaaata tcgtttatat tgaacttgtt tcaagaggat atagagttga
      181 aatcggcaaa gtaaaagact tggaaattga ttttattgca agtaaggata atgaaaggtt
      241 atattatcag gtttcttatt tgatggaaac agaagaaaca agaaaacgag agtttggtgt
      301 gtatgatttt gttagagata attatcctaa atttgtctta tccatggata aagtggattt
      361 tagtcaaaat ggaattattc acaaaaatgt gattgacttt ttattggaaa gcaagtagtt
      421 g
//
LOCUS       DARYXW010000226          413 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.231, whole genome shotgun sequence.
ACCESSION   DARYXW010000226 DARYXW010000000
VERSION     DARYXW010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 413)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 413)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..413
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.231"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            <1..>413
                     /locus_tag="TV191_002006"
     CDS             <1..>413
                     /locus_tag="TV191_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508455.1"
                     /translation="FVPEDVKITELDKEKIHEDHIFQNIKKQGTIIETYVRLKDNQSV
                     FSFDSGKRIDEANLKNYVLVAVNGKELLPDHGIKLSSLVNGQLHPYVKEPSRAYESLK
                     DIIEETESEPFILYISSVYDDIVSRIDEYKMEASI"
BASE COUNT          167 a           52 c           78 g          116 t
ORIGIN      
        1 tttgttccag aagatgttaa aattactgaa cttgacaaag aaaaaattca cgaagatcat
       61 atttttcaaa atataaaaaa acaaggtaca attatagaaa catatgtaag gctgaaagat
      121 aatcaaagtg tattttcttt tgatagtggc aaaagaattg atgaagcaaa cttgaaaaat
      181 tatgttttgg tagcagtaaa tgggaaagaa ttactcccag atcacggaat caaactatca
      241 tctttagtaa atgggcagct acatccatat gttaaagagc ctagtagggc atacgagagt
      301 ttgaaggaca taattgaaga aacagaatct gagccgttta tactctatat cagctcagtt
      361 tacgatgata tagtttcaag aatagacgaa tataagatgg aggcaagtat ata
//
LOCUS       DARYXW010000227          388 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.232, whole genome shotgun sequence.
ACCESSION   DARYXW010000227 DARYXW010000000
VERSION     DARYXW010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 388)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 388)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..388
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.232"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(55..127)
                     /locus_tag="TV191_002007"
     tRNA            complement(55..127)
                     /locus_tag="TV191_002007"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(92..94),aa:Thr,seq:tgt)
     gene            complement(135..216)
                     /locus_tag="TV191_002008"
     tRNA            complement(135..216)
                     /locus_tag="TV191_002008"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(180..182),aa:Leu,seq:tag)
     gene            complement(222..294)
                     /locus_tag="TV191_002009"
     tRNA            complement(222..294)
                     /locus_tag="TV191_002009"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(259..261),aa:Lys,seq:ttt)
     gene            complement(298..370)
                     /locus_tag="TV191_002010"
     tRNA            complement(298..370)
                     /locus_tag="TV191_002010"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(335..337),aa:Asp,seq:gtc)
BASE COUNT           98 a          119 c           85 g           86 t
ORIGIN      
        1 cccaccttgg caaggtggtg ttctaccact gaactacgtt cgcaactcta tcaatgccgg
       61 ctacatgact tgaacacgcg accctctgat tacaaatcag atgctctacc aactgagcta
      121 agccggccta tctatgcggg ttaagggact tgaaccccca cgccgttaag cgccagatcc
      181 taaatctggt gcgtctgcca attccgccaa acccgccttt atgacccgta ctgggctcga
      241 accagtgacc ctttgattaa aagtcaaatg ctctaccaac tgagctaacg agtcctacgg
      301 tcccgacggg aatcgaaccc gcgatcttcg ccgtgacagg gcgacgtgat aaccgctaca
      361 ctacgggacc tattcataac ttatggga
//
LOCUS       DARYXW010000228          372 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.233, whole genome shotgun sequence.
ACCESSION   DARYXW010000228 DARYXW010000000
VERSION     DARYXW010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..372
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.233"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(101..>372)
                     /locus_tag="TV191_002011"
     CDS             complement(101..>372)
                     /locus_tag="TV191_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508456.1"
                     /translation="FTGVNKIVFTWKGYDLYLDSTNANRLSALGWGSTALSGLIPDPI
                     VSKVLAAALGVVSASISYANAAGRGVIVAFVGTFPRGVIHWVASQ"
BASE COUNT          140 a           77 c           48 g          107 t
ORIGIN      
        1 aaaactttcc aaaaaatagt attattttta aataatttat caacaaacac caataatatc
       61 aaattaattg ctaaacacag tatttttaaa tataatgcta tcattgtgaa gccacccaat
      121 gtatcacacc tcttggaaaa gttcctacaa aggcaacaat tactcctctt cctgcagcat
      181 tagcataaga tattgatgca gacacaactc ctaaagcggc tgcaagtacc ttagatacta
      241 tagggtctgg aataagacct gacaaagcag ttgatcccca gcctagtgca gataatctat
      301 tcgcattggt actatctaaa taaagatcat agcctttcca agtaaaaaca attttattta
      361 ccccagtaaa tg
//
LOCUS       DARYXW010000229          371 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.234, whole genome shotgun sequence.
ACCESSION   DARYXW010000229 DARYXW010000000
VERSION     DARYXW010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 371)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 371)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..371
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.234"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(<1..>371)
                     /locus_tag="TV191_002012"
     CDS             complement(<1..>371)
                     /locus_tag="TV191_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HEL1508457.1"
                     /translation="SEIDQKIVRFKGFEDINDRDLRVGTFYYPKNEERKHLILLVCGY
                     EESYLDFKSEIFFWLKNGYTVFCYDVRGTGRSQGRKVGGFTQFLKDCLLSIEYIEKNE
                     TFKKVSLVGHSMGGFAVATSL"
BASE COUNT          126 a           86 c           33 g          126 t
ORIGIN      
        1 gtaacgaagt cgctactgca aaacctccca tactatgccc cactaaagat acctttttaa
       61 aagtttcatt tttttcaatg tattcaatgg acaataagca atccttcaaa aactgagtaa
      121 aacctccaac ttttcttccc tgacttcttc cagttcctct aacatcatag caaaacacag
      181 tatatccatt tttcagccaa aaaaatatct cggatttaaa gtctaaatag gattcttcat
      241 atccacaaac tagtaatatc aaatgtttcc tttcttcatt cttgggataa taaaatgtcc
      301 ctactctcaa atcacgatca ttaatatctt caaatccctt aaatctaact attttttgat
      361 ctatttcaga a
//
LOCUS       DARYXW010000230          368 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.235, whole genome shotgun sequence.
ACCESSION   DARYXW010000230 DARYXW010000000
VERSION     DARYXW010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 368)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 368)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..368
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.235"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(<1..>368)
                     /locus_tag="TV191_002013"
     CDS             complement(<1..>368)
                     /locus_tag="TV191_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HEL1508458.1"
                     /translation="FKGGFLLSSVVGIDSRSTVDIDFLLRNMQLSEENIVQMLNETLK
                     PEEFDDIFYELQNIVPIKEEDQYGGFRANILCKMENIRQIVPLDIATGDVITPHPIDY
                     KYVSSFGEEEIIIKAYPIET"
BASE COUNT          113 a           71 c           46 g          138 t
ORIGIN      
        1 tagtttctat cggataagcc ttgattatta tttcttcttc tccaaaagaa ctcacatact
       61 tataatctat cggatgaggt gtaataacat ctcctgttgc aatgtcaagt ggtacaatct
      121 gtcttatatt ttccatttta cataagatat ttgcacgaaa tcctccatat tgatcttctt
      181 ctttgattgg cacaatgttt tgcaattcat aaaaaatatc gtcgaattct tccggtttta
      241 aagtttcgtt cagcatttga acaatatttt cttctgatag ttgcatattt ctcaaaagaa
      301 agtctatatc tacagtactt cttgaatcaa ttccaactac acttgataac aaaaagccgc
      361 ccttaaaa
//
LOCUS       DARYXW010000231          342 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.236, whole genome shotgun sequence.
ACCESSION   DARYXW010000231 DARYXW010000000
VERSION     DARYXW010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 342)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 342)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..342
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.236"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(<1..>342)
                     /locus_tag="TV191_002014"
     CDS             complement(<1..>342)
                     /locus_tag="TV191_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="Eco57I restriction-modification methylase
                     domain-containing protein"
                     /protein_id="HEL1508459.1"
                     /translation="EYNNMLGVSTKPEKYDVIIGNPPYLKVGKMANEALSMPDICYGS
                     PNLYFLFMEMASFNLVDNGELVFIVPRSWTSGAYFKKFREKFLNEVVLKHIHLFVSRD
                     KVFDKESVLQET"
BASE COUNT          120 a           73 c           40 g          109 t
ORIGIN      
        1 gtttcttgca aaacagactc tttatcaaag actttgtctc tgcttacaaa taaatgaatg
       61 tgcttcaaaa ccacttcatt taaaaacttc tcacgaaact ttttaaagta cgctccagaa
      121 gtccatgatc ttggaacgat aaacaccaat tcgccattat caaccaaatt gaaacttgcc
      181 atctccataa aaagaaaata taaattcggt gatccataac aaatatcagg catggataaa
      241 gcttcattag ccatttttcc aacctttaaa taaggtggat ttcctataat tacatcgtat
      301 ttttcaggtt tagtactcac ccccaacata ttgttatatt ca
//
LOCUS       DARYXW010000232          333 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.237, whole genome shotgun sequence.
ACCESSION   DARYXW010000232 DARYXW010000000
VERSION     DARYXW010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 333)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 333)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..333
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.237"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(<1..>333)
                     /locus_tag="TV191_002015"
     CDS             complement(<1..>333)
                     /locus_tag="TV191_002015"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508460.1"
                     /translation="FSLNEPIAARVTKPTYNRQQLLKNLENSRLATESSRFKSYVARE
                     KLINTLRKQNADLNLITFREKAIEIFNRDLKGNSWVSIRQADEFVETLDDYAQLSVDN
                     GAVSTKAD"
BASE COUNT           86 a           75 c           50 g          122 t
ORIGIN      
        1 aatctgcttt tgtagaaaca gcaccgttat ctactgataa ttgagcataa tcatctaatg
       61 tttctacaaa ttcatcagcc tgtcttatcg aaacccaact atttccttta agatccctat
      121 taaaaatttc tatggctttc tccctaaatg tgataagatt tagatcagca ttctgttttc
      181 ttaaagtatt aattaacttt tctcttgcta catagctctt aaaccttgag ctctctgttg
      241 ccagcctgct gttttcaagg ttcttcaaaa gctgctggcg gttgtaggtc ggtttcgtca
      301 ccctagctgc tattggctca ttcaagctaa acc
//
LOCUS       DARYXW010000233          333 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.238, whole genome shotgun sequence.
ACCESSION   DARYXW010000233 DARYXW010000000
VERSION     DARYXW010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 333)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 333)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..333
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.238"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            96..>333
                     /locus_tag="TV191_002016"
     CDS             96..>333
                     /locus_tag="TV191_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002948623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein FlaR"
                     /protein_id="HEL1508461.1"
                     /translation="MKIVIIGYSGSGKSTLANVLGQHYNCAVLHLDKIHFASNWQERT
                     VSQMVSDISTFMSQKHWIIEGNYSSCLYEERMREA"
BASE COUNT          113 a           47 c           65 g          108 t
ORIGIN      
        1 ggcttttttg cttgtctaaa gaggatttgt ccccaaaata tattctttat gctataatat
       61 aagtcaaagt acagcattga caaaggagac aaagattgaa aattgtaata attggctata
      121 gtggttctgg aaagtcgact ttagcaaatg ttttaggtca acactacaat tgtgctgtac
      181 ttcatttaga caaaattcat tttgcatcaa actggcaaga gcgaacagtt agtcaaatgg
      241 tctctgatat atcaacattt atgtcacaaa aacattggat tattgaaggt aattattcaa
      301 gctgtcttta tgaagagcgt atgagagagg ctg
//
LOCUS       DARYXW010000234          331 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.239, whole genome shotgun sequence.
ACCESSION   DARYXW010000234 DARYXW010000000
VERSION     DARYXW010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 331)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 331)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..331
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.239"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(<1..>331)
                     /locus_tag="TV191_002017"
     CDS             complement(<1..>331)
                     /locus_tag="TV191_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508462.1"
                     /translation="RRSYHRSSFFIKTGSIVMVLYLAIVSILGLTDYLSMRQYIPTWE
                     SSKYYANMACAWSWSYEKDDDKFHEIVIPKLNNLWNSLDDSGAILFNAPNVRKEGMND
                     DEEYLNQQ"
BASE COUNT          106 a           70 c           38 g          117 t
ORIGIN      
        1 ttgttgattt agatactcct catcatcatt cattccctct tttctaacgt ttggggcatt
       61 aaataatatt gctccactat cgtccaaact attccataag ttattcagct ttggaataac
      121 aatttcatgg aacttatcat catctttttc ataactccaa gaccatgcac aagccatatt
      181 tgcataatac tttgagcttt cccaagttgg aatgtattgt ctcatactca agtaatcagt
      241 gagtcctaaa atacttacaa ttgctagata aagaaccata acaatcgacc ctgtttttat
      301 aaaaaaagaa cttctatgat aacttcttct a
//
LOCUS       DARYXW010000235          316 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.240, whole genome shotgun sequence.
ACCESSION   DARYXW010000235 DARYXW010000000
VERSION     DARYXW010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..316
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.240"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            <1..>316
                     /locus_tag="TV191_002018"
     CDS             <1..>316
                     /locus_tag="TV191_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1508463.1"
                     /translation="YLKVMGNNYKYPYFNQLSIYTVNENATACAEYDYWKSIGRNVNR
                     GEKGIPVLDIEREKIKYIFDASQTVSLNHNISEVKLWEYSNNKHVAALDTLIDVFKEK
                     NSN"
BASE COUNT          131 a           39 c           60 g           86 t
ORIGIN      
        1 tatctcaaag tgatgggaaa taactataaa tatccgtact ttaaccagct tagcatatat
       61 acggtaaatg aaaatgcaac tgcttgtgca gaatatgact attggaaaag tataggaaga
      121 aatgtaaata gaggagaaaa aggaatacct gttttagaca ttgaaagaga gaagataaag
      181 tatatctttg atgcaagtca gacagtaagt ttaaatcaca acatttctga agtaaagtta
      241 tgggaatata gcaataataa gcatgtagct gccttagata ctcttatcga tgttttcaaa
      301 gaaaaaaaca gtaacc
//
LOCUS       DARYXW010000236          315 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.241, whole genome shotgun sequence.
ACCESSION   DARYXW010000236 DARYXW010000000
VERSION     DARYXW010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.241"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            <1..>315
                     /locus_tag="TV191_002019"
     CDS             <1..>315
                     /locus_tag="TV191_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1508464.1"
                     /translation="LIGYVSQNNFLFNESIMENIRMGNPDASDEEVIEVSKICACHDF
                     IMELEEGYNSNVGSLGSKLSGGQRQRISIARMMLKNAPIILLDEATAFIDPDNEEKIQ
                     GAI"
BASE COUNT          113 a           35 c           71 g           96 t
ORIGIN      
        1 ttaattggtt atgtatcgca gaataacttt ctatttaatg aaagtattat ggaaaatata
       61 cggatgggaa atcctgatgc aagtgacgaa gaagttatag aggtatcaaa gatttgcgct
      121 tgccatgatt ttattatgga acttgaagaa ggatataatt ccaatgtggg aagtcttgga
      181 agtaagcttt caggtggaca aaggcaaagg atttctatag cgagaatgat gttgaaaaat
      241 gctcctatta tattgcttga tgaagctaca gcatttatag atccagataa tgaagaaaaa
      301 atacaaggtg ctatt
//
LOCUS       DARYXW010000237          314 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.242, whole genome shotgun sequence.
ACCESSION   DARYXW010000237 DARYXW010000000
VERSION     DARYXW010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 314)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 314)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..314
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.242"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
BASE COUNT          119 a           62 c           42 g           91 t
ORIGIN      
        1 gaagataaaa tttcactcat catattgaaa tatgaaaaag aaattcaaga aaaaactcaa
       61 aaacttcttg agtttattcc cgaaaaaaca caaggaacaa taatggttac aaagtcgata
      121 ataaaagcat ttgttagtat taaaccggta ttgtatcgac acaagaaacg acaaaagttc
      181 taaacttatg ccccaatttt gccccaatgg ttctttcttg attctttggt gaactaaaat
      241 tattcagact cagaaagttc tgccataaca tcggatatcc gctcgattgt cacaacctcc
      301 caatctctta tctc
//
LOCUS       DARYXW010000238          313 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.243, whole genome shotgun sequence.
ACCESSION   DARYXW010000238 DARYXW010000000
VERSION     DARYXW010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..313
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.243"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            40..>313
                     /locus_tag="TV191_002020"
     CDS             40..>313
                     /locus_tag="TV191_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEL1508465.1"
                     /translation="MYKILVVDDDYEILKLMRTILEMKNYKVTTYQEVTFPINFRDFQ
                     GFDLILLDVMMPNVEGTQICQLIRDKVASPIIFVSAKDTEDDIIKGL"
BASE COUNT          109 a           36 c           57 g          111 t
ORIGIN      
        1 tagtgtaaaa taacagtgta actattatga ggtaagacta tgtataagat tctagttgtt
       61 gatgatgatt atgagatttt aaaacttatg cggaccattc ttgagatgaa aaattacaag
      121 gtaacaacct atcaagaagt gacttttcca atcaatttta gagattttca agggtttgac
      181 ttgattttat tagatgtcat gatgcctaat gttgaaggta cacaaatttg tcaattaatc
      241 cgagataaag ttgcttctcc tattatcttt gttagtgcta aagatactga agacgatatt
      301 attaaaggat taa
//
LOCUS       DARYXW010000239          305 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.244, whole genome shotgun sequence.
ACCESSION   DARYXW010000239 DARYXW010000000
VERSION     DARYXW010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..305
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.244"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            <1..>305
                     /locus_tag="TV191_002021"
     CDS             <1..>305
                     /locus_tag="TV191_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HEL1508466.1"
                     /translation="ADKKVHKLEAQIEADRPKVLFADAVSASKSSCLIGELAKILKQN
                     GINIGQNKLFQWLRTNGYLISRRGESWNQPTQKSMQLGLFELKKTAINHSDGHTTTNV
                     "
BASE COUNT          106 a           59 c           67 g           73 t
ORIGIN      
        1 gcggacaaga aagtgcataa attagaagct cagattgagg ctgaccgacc caaagtacta
       61 tttgctgatg ccgtaagtgc tagcaaatca tcttgtctga ttggtgagtt agctaaaatc
      121 ctgaaacaga atggaatcaa tattggtcag aataagctat ttcagtggct tagaacgaac
      181 ggttatctaa ttagcagacg cggcgagtca tggaatcagc caacgcaaaa aagtatgcag
      241 cttggattgt ttgaactcaa aaaaacagcc atcaatcact ctgacggtca cactacaaca
      301 aatgt
//
LOCUS       DARYXW010000240          295 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.denovo.245, whole genome shotgun sequence.
ACCESSION   DARYXW010000240 DARYXW010000000
VERSION     DARYXW010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 295)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 295)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..295
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.denovo.245"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(<1..>295)
                     /locus_tag="TV191_002022"
     CDS             complement(<1..>295)
                     /locus_tag="TV191_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1508467.1"
                     /translation="IEQNTTLEFEDSRQKYQYRKDLASNTGMFLSFFSQVACMVAGIF
                     FVRNNLLTVGLLVASIQLLNGVFGPLQSFLYNKNLIKSTGTILTSIQEVLDKTN"
BASE COUNT          101 a           48 c           42 g          104 t
ORIGIN      
        1 aatttgtttt atctagaact tcttgaatac ttgttaaaat agtacctgtg cttttgatca
       61 aatttttatt gtaaaggaaa gactgtagag ggccaaacac tccatttaat aactgaatac
      121 tggccactaa tagtccaact gttagtagat tattccttac aaaaaatata ccagcaacca
      181 tacaggctac ttgagaaaag aagctcaaaa acattcctgt atttgaagct aaatcttttc
      241 tgtattgata tttctgtcta gaatcttcaa attctaaagt agtattttgt tcgat
//
LOCUS       DARYXW010000241         6233 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611955-rid16720333.guided.102, whole genome shotgun sequence.
ACCESSION   DARYXW010000241 DARYXW010000000
VERSION     DARYXW010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611955
            Sequence Read Archive: SRR18311086
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574815.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574815.1
            Genome Coverage       :: 165x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/12/2023 21:55:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,026
            CDSs (total)                      :: 1,990
            Genes (coding)                    :: 1,912
            CDSs (with protein)               :: 1,912
            Genes (RNA)                       :: 36
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            CDSs (without protein)            :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 33 of 78
            Pseudo Genes (incomplete)         :: 28 of 78
            Pseudo Genes (internal stop)      :: 24 of 78
            Pseudo Genes (multiple problems)  :: 7 of 78
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6233
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611955-rid16720333.guided.102"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: TN"
                     /collection_date="2020-07-31"
                     /collected_by="Kord Animal Health Diagnostic Laboratory,
                     Nashville, TN"
     gene            complement(<1..1880)
                     /locus_tag="TV191_002023"
     CDS             complement(<1..1880)
                     /locus_tag="TV191_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HEL1508468.1"
                     /translation="MKKHFVLKSSVLGVFAGVSMLVTGVQADQVDVQFLGVNDFHGAL
                     DTTGSAYMPEGKVSNAGTAAQLAAYLDDAEADFKQTSPDGTSIRVQPGDMVGASPANS
                     GLLQDEPTVKVFNQMGFEYGTLGNHEFDEGLAEFNRIMTGTAPAEDSAINDITKQYEH
                     EASNQTLVIANVVDKETNTIPFGWKPYAVKEVPVNDKSVKVGFIGVVTTEIPNLVLKQ
                     NYEQYDYLDSAETIVKYAKELQEQQVNAIVVLAHIPATSDNGVVHDEMAAVMEKVNQL
                     YPEHSVDIVFAGHNHQYTNGTIGTTRVVQAVSQGKAYADVRGTLDTDLNDFVATPEAK
                     VIAVAPGIKTGNADIQAIVDQANDIVKTVTELKIGTAATSSTISKTENEDKESPVGNL
                     ITTAQLTIGRKTFPHVDFAMTNNGGIRADLVVKEDQTITWGAAQAVQPFGNILQVVQM
                     TGQQIYDVLNQQYDEDQKYFLQMSGLKYTYTANEANDPSTPFKVVKAYKDNGEEIDPA
                     AQYTLIINDFLYGGGDGFSVFKDAKLLGAINPDTEVFIEYIKDLEAAGKTVSAGINGV
                     KTYVTASLEGSTQSDHTGKHEIINRVFKNREGKVLATELVSDLFTPAQNANPATSIKP
                     LAA"
     gene            2329..4050
                     /locus_tag="TV191_002024"
     CDS             2329..4050
                     /locus_tag="TV191_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1508469.1"
                     /translation="MLTLIVQHIKQKKWIYILIAMTLVIYDASLVIPTRVIQDLVDLM
                     SRHQLSSGALVRHVIILLATAVVSYGVAYLWHLHLFQEAVHFKFDIQQRAFRKLVFMR
                     TPFYEKFRSGDMITRFSTDVEALMDLIGYGLMIILYAGGMIAFIIPTMFLISWKMTLI
                     GIVPILLMMVMIYGVTKKQEHLVEEAREAISSLSDEVLETVEGIRVMRAYSKKDYLAL
                     HFAQKTQNLADKWNQVAKYRALYFPLYSVMIAISTVIILMVGLQLIASSEVTLGQVIA
                     LQLYLVSLVEPFGMLSDFILVYQTGKTSFGKINELIETSDDMEPDGQLELESFDQIAF
                     IDYSFTYANSSRPSLEKINLTLKKGQTLGIVGKTGSGKTTLVRQFLRQYPLGQGQLMI
                     NHRSVLDYKRQSLERQIGYVPQEHILFSKTVAQNIAMGKKAATTEEILEAIETAAFTR
                     DVQGMAKGLDTEIGERGLSISGGQKQRISIARAFLSQPDLLILDDSLSAVDARTETDI
                     IRHIQDERKGKTTLIVSHRLSAIQHADWVIVLDQGQIVEEGQPQQLLAQKGWYYEQYQ
                     RQQAQEV"
     gene            4052..5215
                     /locus_tag="TV191_002025"
                     /pseudo
     CDS             4052..5215
                     /locus_tag="TV191_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677880.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            5367..6143
                     /locus_tag="TV191_002026"
     CDS             5367..6143
                     /locus_tag="TV191_002026"
                     /inference="COORDINATES: protein motif:HMM:NF022077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HEL1508470.1"
                     /translation="MAEVITIANRKGGVGKTTTTLNLAYSLKELGKKVLVIDLDPQAN
                     LTRCFDMGNTENIKTIGHLLMVELEEEESYLVEGYTKSYDEIDIIPSSIFLSAVETQM
                     RAETGSERILSEIIRRVKENYDYILIDTSPSLSVLTINALCASDSVLIVADTQLFAVV
                     GINELLKTVQKIKKRVNPKLKVQGILLTMCENRTNLSKTLMEQVEEMFQKKIKVFQTK
                     IPKTVKVGEAIYSGQSIKKYAKGSSVDIAYDNLAKEICYE"
BASE COUNT         1835 a         1137 c         1393 g         1868 t
ORIGIN      
        1 gctgctagag gcttgatgct tgtggcagga ttagcatttt gagcaggcgt aaataggtca
       61 gagacaagct cagtagcaag caccttgccc tcacgattct taaagacgcg gttgatgatc
      121 tcgtgcttgc cggtatgatc actttgagta gagccttcaa gactggcagt gacataggtt
      181 ttcacaccgt taataccagc acttacagtc tttccagctg cttcaaggtc cttgatgtat
      241 tcgataaaga cctcagtatc aggattaatg gctcctagta gcttagcgtc cttaaagacg
      301 gagaagccat caccaccgcc atataggaag tcgttgatga ttagggtgta ttgagctgct
      361 ggatcaattt cttcaccatt atctttataa gcctttacta ccttaaacgg tgttgaagga
      421 tcgttagcct cattagctgt ataagtgtat ttgagtccag acatttgaag gaagtatttt
      481 tggtcttcat cgtattgttg gttcaagaca tcatagattt gttggccagt catttgaacg
      541 acctgaagaa tattgccaaa tggttgaaca gcctgtgcag ctccccaggt aatggtttga
      601 tcctctttga ccaccaagtc agcgcgaata ccgccattat ttgtcatggc aaaatcaaca
      661 tgagggaagg tttttctacc aatggttaat tgggcagttg ttatcaaatt gccaacagga
      721 gattccttgt cttcgttttc tgttttagaa atcgttgaag aggtagctgc tgtaccgatc
      781 tttagctcgg taacggtttt gacaatgtca ttggcttgat caacaatggc ttgaatgtcg
      841 gcattgcctg tttttatgcc aggagcaacg gcaatgacct ttgcttcagg agtggctaca
      901 aaatcattga ggtcagtgtc tagtgttcca cgaacatctg cataggcttt cccctgtgaa
      961 acagcctgaa cgacacgtgt tgtgccaatg gtaccgttgg tgtattggtg gttgtgacca
     1021 gcaaagacaa tatccacact atgctcagga taaagctggt taaccttttc cataactgct
     1081 gccatctcat catgaactac cccgttatca cttgttgctg ggatatgagc taggacaaca
     1141 atcgcattga cctgctgctc ttggagctct ttagcatatt taacgatggt ttctgcagag
     1201 tctaggtaat catattgttc ataattttgt tttaggacaa ggtttggaat ttctgttgtc
     1261 acaacaccga taaagcccac cttgactgac ttatcattaa ctgggacttc tttgacagca
     1321 taaggcttcc agccaaaagg aatcgtgttg gtctccttgt caacgacatt tgcaatgaca
     1381 agggtttgat ttgaagcttc atgctcgtat tgcttagtaa tgtcgttgat agctgagtct
     1441 tcagcaggtg cagtgcctgt catgatacgg ttgaattcag ctaagccctc atcgaattcg
     1501 tgattcccaa gggttccgta ttcaaagccc atctggttga ataccttaac cgttggctcg
     1561 tcctgtaata gtccagaatt agcaggacta gctccgacca tatctcctgg ttgaacacga
     1621 atgcttgtcc catctgggct tgtttgctta aagtcagcct ctgcatcgtc cagataagca
     1681 gctaattgtg ctgcggtacc agcgttagat acctttcctt ctggcatgta ggcagagccg
     1741 gttgtgtcta aggcaccatg aaagtcattg acaccaagaa attgcacgtc tacctgatcg
     1801 gcctgcacgc cggttactag catagaaact ccggcaaaga caccaagaac actacttttt
     1861 aaaacaaaat gctttttcat aaacgctcct aaaagtttaa agtattgtca caagttaagt
     1921 gtactattat ttaaatgaga attcaacaaa aattaataaa aaagctaaca aaaattcaac
     1981 gatagcgttt gctaatcact gaaaacgttt aaaatgcaaa cattggaagc gttttttgta
     2041 aaaaaataga agaactatcc aaaaaaggct ttacaagccc agtattctat gataagatgt
     2101 taggcagatt aaaagaaagg agaaattaat aatgatccgt ttcattcaac tatttaacca
     2161 ttattacgat agtctccttt ctaaccaaaa cagttagttt cttttagttt cactaaatag
     2221 aaatagtaga gcccgcggta ggaaggatat cttattgcgg gctttttgtg tgcaaaaatc
     2281 ctattttaag acagcttgaa ataggttagt tcagaaatgg aggatatgat gctgacctta
     2341 attgttcaac atattaagca aaagaaatgg atttatatcc ttattgcaat gactttagtg
     2401 atatatgatg cctcacttgt gataccaaca agggttattc aagacttggt tgatttgatg
     2461 tcaaggcatc agctaagctc aggggcattg gtgaggcatg ttatcattct tttggctacg
     2521 gcagtagtgt cttatggggt tgcttatttg tggcatcttc atttatttca ggaggcagtt
     2581 cattttaagt ttgatattca gcagcgtgcc tttcgaaagc ttgtttttat gagaacgcct
     2641 ttttatgaga aatttcgctc aggtgacatg atcacgcgtt tttcaacaga tgtcgaagca
     2701 cttatggacc ttatcggcta tggcttgatg attatcctat atgctggtgg tatgattgct
     2761 tttattattc cgaccatgtt tttgatttct tggaaaatga ccttgatagg aatagtaccg
     2821 attttgctta tgatggtgat gatctatggt gtgacgaaaa agcaagagca tttggttgaa
     2881 gaggcgcgtg aggcgatttc aagccttagt gatgaggtac tagaaaccgt tgagggcatt
     2941 agagtgatgc gtgcttacag taaaaaagat tatttggcac ttcattttgc tcaaaagact
     3001 cagaatttgg cagataaatg gaatcaggtg gccaagtatc gtgccttgta ctttcctctt
     3061 tacagcgtca tgattgccat tagtacagta atcattttaa tggtaggcct acagctcata
     3121 gcaagctcag aggtaacact tggtcaagtc attgcgctgc agctttatct ggtgtctttg
     3181 gtggagccct ttggcatgct gtcagacttt attttggttt atcagacagg aaagacctct
     3241 tttggtaaga ttaatgaact catcgaaaca agtgatgata tggagcctga tggccagctt
     3301 gagttagaga gctttgatca gattgctttt atagactata gctttaccta tgccaatagt
     3361 tctaggccta gcttagaaaa gatcaattta accctgaaaa agggacaaac cttagggatt
     3421 gttggtaaaa caggctctgg taaaacaacc cttgtcaggc agtttttgag acaataccct
     3481 cttgggcagg ggcagctgat gattaatcat cgtagtgtct tggattataa gcgtcaatca
     3541 cttgagcgtc aaattggcta tgtgccacag gagcatatcc tgttttcaaa aacggttgct
     3601 caaaacattg cgatggggaa aaaggcagct acaactgagg aaatcttgga ggcgattgaa
     3661 actgcggcct ttacgcgtga tgttcaagga atggcaaagg gcttggatac tgagattgga
     3721 gagcgtggtc tgtctatttc aggaggtcaa aagcagcgta tttcgattgc cagagccttt
     3781 ttgtcccagc cagatttgct gattttagat gattccctgt cggcagttga tgctagaaca
     3841 gagactgata ttattcgaca cattcaagac gaaagaaagg gaaagacaac acttattgtt
     3901 agccatcgct tgtctgcgat tcagcatgcc gattgggtta ttgttctgga tcaggggcag
     3961 atagtagagg aaggtcagcc ccaacaactt ttagctcaga agggctggta ttatgaacag
     4021 taccagcgtc agcaggctca ggaggtttaa gatgacccta tttataaaat taataaaaga
     4081 aattaaagct gtgaccttgg ctttttccct ggcaataggc tttttgctag tggcaacagc
     4141 tggaggtcag atggctccct tattgttgca acaaacgatt gatcattact tgactccgat
     4201 agctagagga aaagaggtac cgattgaagg ctttcagcgc ttgctcctgc tgtatttgct
     4261 gttaattgtg ataacagcag ttttgcgtta tatctcttat cgaatgctgg tttattcctc
     4321 taataggatc gttgctaatc ttcgtaatcg agcctttgat gtcatgcaga ggctgccgat
     4381 agcttatttt gatcatcagc ctgcaggaaa gattgcaact aggattgtta atgatactga
     4441 aaccctgaag aatcaatttt atgataacct tttgtctcaa attattgtca gtctttcaca
     4501 aattattttt atttatgtgg tgatgattta ccttgatgtg aagtcaggct tgctgttgct
     4561 gcttattatg ccactctttt atggcatgca atggctgtat aaaagcttga ctgaccagcc
     4621 aatgaaggat ttttatcagg ctaggagcgc tgtcaacaca caagtcaacg aaaccatgaa
     4681 tggtgtttct attattcagc tttatcatca agaggatacg atcttagagg aatttgaaga
     4741 gcagatccac cagatgaaaa cagctgatga taggattatt tttgcagagt cagttgcttc
     4801 atggaccctg acggaattgg taaagtatgg catgattgcc gctattttgg ctgttattgg
     4861 ttaccagttc ttgcagggga gatcaggcat cacagttggt aagctcttta tttacgtcaa
     4921 ttatttgctg cgcttgtttg atttattaag tatgctggtt aggcagctac ctaatattca
     4981 gcgctcaaca gcgacaggaa cgcgcctaat gaagctgctt gaggcgcaga cagagccgga
     5041 taaagcacga gcaattgagc taacagatgg tactgtggat tttaccaagg tgtattttgc
     5101 ttacgaaaat ggcaagacag ttttatctga tattaccatt catgctgata aaggggagac
     5161 ggttgcccta gtagggcata ctggctctgg ggacaatgct ataatgatga tagtacaata
     5221 aatccaagta aaatcaatgg ttaaaggctt ccgcaaaact tttaaacttg atgatggatt
     5281 gaggctatca tcttttttta tatctaaaat tatataaaag tatagcataa aatgaaatct
     5341 ctgtatagag aagaaggagg gactttatgg cagaagtgat aaccatagcc aatcgaaaag
     5401 gcggagttgg aaaaacaact acaactctaa accttgccta ttcactaaaa gaactgggga
     5461 aaaaagtatt agtcattgac cttgatccac aagctaatct tacaagatgt tttgatatgg
     5521 gaaatacaga aaatataaaa accatagggc atttgttaat ggtagaactg gaggaagaag
     5581 aaagctattt ggtagagggc tataccaaat cttatgatga gatagatatt atcccctcaa
     5641 gcattttctt atccgccgtt gaaacacaaa tgagagcaga aacaggaagt gaacgtatat
     5701 tatcggaaat tattaggagg gtaaaagaga attatgacta tattctcata gatacatcac
     5761 catcacttag tgttttgact ataaatgctc tttgtgcctc agacagtgtc cttatagtag
     5821 cggatacaca gctgttcgca gttgttggaa tcaatgaact tttaaaaact gttcaaaaaa
     5881 taaaaaagag agtgaatccg aaactgaaag tgcaggggat tttactaacc atgtgtgaga
     5941 atagaaccaa tctgtccaaa acactgatgg agcaagtaga agaaatgttc caaaagaaaa
     6001 tcaaggtctt tcaaaccaaa attccgaaaa cagttaaagt tggggaagcc atctatagcg
     6061 ggcaaagcat aaaaaaatat gcaaaaggca gtagtgtaga cattgcctat gacaatctgg
     6121 caaaggagat ctgctatgag taaaaaactt ctaaagagag aaatcaccga tgccgtagat
     6181 tttttgcttg atgatggaaa tgccttggaa caaggaaata tacagaatat aga
//
